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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:KIAA1217-RPA2 (FusionGDB2 ID:42093)

Fusion Gene Summary for KIAA1217-RPA2

check button Fusion gene summary
Fusion gene informationFusion gene name: KIAA1217-RPA2
Fusion gene ID: 42093
HgeneTgene
Gene symbol

KIAA1217

RPA2

Gene ID

56243

84172

Gene nameKIAA1217RNA polymerase I subunit B
SynonymsETL4|SKTA135|RPA135|RPA2|Rpo1-2
Cytomap

10p12.2-p12.1

2q14.1

Type of geneprotein-codingprotein-coding
Descriptionsickle tail protein homologlikely orthologue of Mus musculus enhancer trap locus 4DNA-directed RNA polymerase I subunit RPA2DNA-directed RNA polymerase I 135 kDa polypeptideDNA-directed RNA polymerase I 135kDa polypeptideRNA polymerase I subunit 2polymerase (RNA) I polypeptide B, 128kDapolymerase (RNA) I subunit B
Modification date2020031320200313
UniProtAcc

Q5T5P2

.
Ensembl transtripts involved in fusion geneENST00000376462, ENST00000481700, 
ENST00000458595, ENST00000376454, 
ENST00000376452, ENST00000430453, 
ENST00000307544, ENST00000396446, 
ENST00000396445, ENST00000376451, 
ENST00000373912, ENST00000373909, 
ENST00000313433, 
Fusion gene scores* DoF score22 X 21 X 11=50823 X 3 X 2=18
# samples 243
** MAII scorelog2(24/5082*10)=-4.40429006444484
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(3/18*10)=0.736965594166206
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: KIAA1217 [Title/Abstract] AND RPA2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointKIAA1217(24508838)-RPA2(28220617), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across KIAA1217 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across RPA2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4Non-CancerTCGA-HU-A4GC-11AKIAA1217chr10

24508838

+RPA2chr1

28220617

-


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Fusion Gene ORF analysis for KIAA1217-RPA2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000376462ENST00000373912KIAA1217chr10

24508838

+RPA2chr1

28220617

-
In-frameENST00000376462ENST00000373909KIAA1217chr10

24508838

+RPA2chr1

28220617

-
In-frameENST00000376462ENST00000313433KIAA1217chr10

24508838

+RPA2chr1

28220617

-
intron-3CDSENST00000481700ENST00000373912KIAA1217chr10

24508838

+RPA2chr1

28220617

-
intron-3CDSENST00000481700ENST00000373909KIAA1217chr10

24508838

+RPA2chr1

28220617

-
intron-3CDSENST00000481700ENST00000313433KIAA1217chr10

24508838

+RPA2chr1

28220617

-
In-frameENST00000458595ENST00000373912KIAA1217chr10

24508838

+RPA2chr1

28220617

-
In-frameENST00000458595ENST00000373909KIAA1217chr10

24508838

+RPA2chr1

28220617

-
In-frameENST00000458595ENST00000313433KIAA1217chr10

24508838

+RPA2chr1

28220617

-
In-frameENST00000376454ENST00000373912KIAA1217chr10

24508838

+RPA2chr1

28220617

-
In-frameENST00000376454ENST00000373909KIAA1217chr10

24508838

+RPA2chr1

28220617

-
In-frameENST00000376454ENST00000313433KIAA1217chr10

24508838

+RPA2chr1

28220617

-
In-frameENST00000376452ENST00000373912KIAA1217chr10

24508838

+RPA2chr1

28220617

-
In-frameENST00000376452ENST00000373909KIAA1217chr10

24508838

+RPA2chr1

28220617

-
In-frameENST00000376452ENST00000313433KIAA1217chr10

24508838

+RPA2chr1

28220617

-
intron-3CDSENST00000430453ENST00000373912KIAA1217chr10

24508838

+RPA2chr1

28220617

-
intron-3CDSENST00000430453ENST00000373909KIAA1217chr10

24508838

+RPA2chr1

28220617

-
intron-3CDSENST00000430453ENST00000313433KIAA1217chr10

24508838

+RPA2chr1

28220617

-
intron-3CDSENST00000307544ENST00000373912KIAA1217chr10

24508838

+RPA2chr1

28220617

-
intron-3CDSENST00000307544ENST00000373909KIAA1217chr10

24508838

+RPA2chr1

28220617

-
intron-3CDSENST00000307544ENST00000313433KIAA1217chr10

24508838

+RPA2chr1

28220617

-
intron-3CDSENST00000396446ENST00000373912KIAA1217chr10

24508838

+RPA2chr1

28220617

-
intron-3CDSENST00000396446ENST00000373909KIAA1217chr10

24508838

+RPA2chr1

28220617

-
intron-3CDSENST00000396446ENST00000313433KIAA1217chr10

24508838

+RPA2chr1

28220617

-
intron-3CDSENST00000396445ENST00000373912KIAA1217chr10

24508838

+RPA2chr1

28220617

-
intron-3CDSENST00000396445ENST00000373909KIAA1217chr10

24508838

+RPA2chr1

28220617

-
intron-3CDSENST00000396445ENST00000313433KIAA1217chr10

24508838

+RPA2chr1

28220617

-
intron-3CDSENST00000376451ENST00000373912KIAA1217chr10

24508838

+RPA2chr1

28220617

-
intron-3CDSENST00000376451ENST00000373909KIAA1217chr10

24508838

+RPA2chr1

28220617

-
intron-3CDSENST00000376451ENST00000313433KIAA1217chr10

24508838

+RPA2chr1

28220617

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000376462KIAA1217chr1024508838+ENST00000373912RPA2chr128220617-17429236201102160
ENST00000376462KIAA1217chr1024508838+ENST00000373909RPA2chr128220617-134292359396165
ENST00000376462KIAA1217chr1024508838+ENST00000313433RPA2chr128220617-11939236201102160
ENST00000458595KIAA1217chr1024508838+ENST00000373912RPA2chr128220617-1576757358936192
ENST00000458595KIAA1217chr1024508838+ENST00000373909RPA2chr128220617-1176757358936192
ENST00000458595KIAA1217chr1024508838+ENST00000313433RPA2chr128220617-1027757358936192
ENST00000376454KIAA1217chr1024508838+ENST00000373912RPA2chr128220617-120338412563183
ENST00000376454KIAA1217chr1024508838+ENST00000373909RPA2chr128220617-80338412563183
ENST00000376454KIAA1217chr1024508838+ENST00000313433RPA2chr128220617-65438412563183
ENST00000376452KIAA1217chr1024508838+ENST00000373912RPA2chr128220617-11943753554183
ENST00000376452KIAA1217chr1024508838+ENST00000373909RPA2chr128220617-7943753554183
ENST00000376452KIAA1217chr1024508838+ENST00000313433RPA2chr128220617-6453753554183

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000376462ENST00000373912KIAA1217chr1024508838+RPA2chr128220617-0.043908140.9560918
ENST00000376462ENST00000373909KIAA1217chr1024508838+RPA2chr128220617-0.0291925720.97080743
ENST00000376462ENST00000313433KIAA1217chr1024508838+RPA2chr128220617-0.03720920.96279085
ENST00000458595ENST00000373912KIAA1217chr1024508838+RPA2chr128220617-0.003284350.99671566
ENST00000458595ENST00000373909KIAA1217chr1024508838+RPA2chr128220617-0.0049928670.99500716
ENST00000458595ENST00000313433KIAA1217chr1024508838+RPA2chr128220617-0.0068886790.9931114
ENST00000376454ENST00000373912KIAA1217chr1024508838+RPA2chr128220617-0.0015353610.9984647
ENST00000376454ENST00000373909KIAA1217chr1024508838+RPA2chr128220617-0.0019903790.9980096
ENST00000376454ENST00000313433KIAA1217chr1024508838+RPA2chr128220617-0.0024921520.9975078
ENST00000376452ENST00000373912KIAA1217chr1024508838+RPA2chr128220617-0.0016978370.9983021
ENST00000376452ENST00000373909KIAA1217chr1024508838+RPA2chr128220617-0.0019422180.9980578
ENST00000376452ENST00000313433KIAA1217chr1024508838+RPA2chr128220617-0.0024153820.9975846

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Fusion Genomic Features for KIAA1217-RPA2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for KIAA1217-RPA2


check button Go to

FGviewer for the breakpoints of chr10:24508838-chr1:28220617

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
KIAA1217

Q5T5P2

.
FUNCTION: Required for normal development of intervertebral disks. {ECO:0000250|UniProtKB:A2AQ25}.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneRPA2chr10:24508838chr1:28220617ENST0000037390969247_270219.0279.0Compositional biasNote=Asp/Glu-rich (acidic)
TgeneRPA2chr10:24508838chr1:28220617ENST0000037391269247_270211.0271.0Compositional biasNote=Asp/Glu-rich (acidic)

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneKIAA1217chr10:24508838chr1:28220617ENST00000307544+1141464_14900933.0Coiled coilOntology_term=ECO:0000255
HgeneKIAA1217chr10:24508838chr1:28220617ENST00000307544+1141656_16860933.0Coiled coilOntology_term=ECO:0000255
HgeneKIAA1217chr10:24508838chr1:28220617ENST00000307544+114557_5810933.0Coiled coilOntology_term=ECO:0000255
HgeneKIAA1217chr10:24508838chr1:28220617ENST00000307544+114644_6850933.0Coiled coilOntology_term=ECO:0000255
HgeneKIAA1217chr10:24508838chr1:28220617ENST00000307544+114957_9850933.0Coiled coilOntology_term=ECO:0000255
HgeneKIAA1217chr10:24508838chr1:28220617ENST00000376451+1151464_149001466.0Coiled coilOntology_term=ECO:0000255
HgeneKIAA1217chr10:24508838chr1:28220617ENST00000376451+1151656_168601466.0Coiled coilOntology_term=ECO:0000255
HgeneKIAA1217chr10:24508838chr1:28220617ENST00000376451+115557_58101466.0Coiled coilOntology_term=ECO:0000255
HgeneKIAA1217chr10:24508838chr1:28220617ENST00000376451+115644_68501466.0Coiled coilOntology_term=ECO:0000255
HgeneKIAA1217chr10:24508838chr1:28220617ENST00000376451+115957_98501466.0Coiled coilOntology_term=ECO:0000255
HgeneKIAA1217chr10:24508838chr1:28220617ENST00000376454+2211464_1490118.01944.0Coiled coilOntology_term=ECO:0000255
HgeneKIAA1217chr10:24508838chr1:28220617ENST00000376454+2211656_1686118.01944.0Coiled coilOntology_term=ECO:0000255
HgeneKIAA1217chr10:24508838chr1:28220617ENST00000376454+221557_581118.01944.0Coiled coilOntology_term=ECO:0000255
HgeneKIAA1217chr10:24508838chr1:28220617ENST00000376454+221644_685118.01944.0Coiled coilOntology_term=ECO:0000255
HgeneKIAA1217chr10:24508838chr1:28220617ENST00000376454+221957_985118.01944.0Coiled coilOntology_term=ECO:0000255
HgeneKIAA1217chr10:24508838chr1:28220617ENST00000396445+1131464_14900907.0Coiled coilOntology_term=ECO:0000255
HgeneKIAA1217chr10:24508838chr1:28220617ENST00000396445+1131656_16860907.0Coiled coilOntology_term=ECO:0000255
HgeneKIAA1217chr10:24508838chr1:28220617ENST00000396445+113557_5810907.0Coiled coilOntology_term=ECO:0000255
HgeneKIAA1217chr10:24508838chr1:28220617ENST00000396445+113644_6850907.0Coiled coilOntology_term=ECO:0000255
HgeneKIAA1217chr10:24508838chr1:28220617ENST00000396445+113957_9850907.0Coiled coilOntology_term=ECO:0000255
HgeneKIAA1217chr10:24508838chr1:28220617ENST00000396446+1121464_14900867.0Coiled coilOntology_term=ECO:0000255
HgeneKIAA1217chr10:24508838chr1:28220617ENST00000396446+1121656_16860867.0Coiled coilOntology_term=ECO:0000255
HgeneKIAA1217chr10:24508838chr1:28220617ENST00000396446+112557_5810867.0Coiled coilOntology_term=ECO:0000255
HgeneKIAA1217chr10:24508838chr1:28220617ENST00000396446+112644_6850867.0Coiled coilOntology_term=ECO:0000255
HgeneKIAA1217chr10:24508838chr1:28220617ENST00000396446+112957_9850867.0Coiled coilOntology_term=ECO:0000255
HgeneKIAA1217chr10:24508838chr1:28220617ENST00000458595+2181464_1490118.01350.0Coiled coilOntology_term=ECO:0000255
HgeneKIAA1217chr10:24508838chr1:28220617ENST00000458595+2181656_1686118.01350.0Coiled coilOntology_term=ECO:0000255
HgeneKIAA1217chr10:24508838chr1:28220617ENST00000458595+218557_581118.01350.0Coiled coilOntology_term=ECO:0000255
HgeneKIAA1217chr10:24508838chr1:28220617ENST00000458595+218644_685118.01350.0Coiled coilOntology_term=ECO:0000255
HgeneKIAA1217chr10:24508838chr1:28220617ENST00000458595+218957_985118.01350.0Coiled coilOntology_term=ECO:0000255
HgeneKIAA1217chr10:24508838chr1:28220617ENST00000307544+1141794_19050933.0Compositional biasSer-rich
HgeneKIAA1217chr10:24508838chr1:28220617ENST00000307544+114295_3640933.0Compositional biasPro-rich
HgeneKIAA1217chr10:24508838chr1:28220617ENST00000376451+1151794_190501466.0Compositional biasSer-rich
HgeneKIAA1217chr10:24508838chr1:28220617ENST00000376451+115295_36401466.0Compositional biasPro-rich
HgeneKIAA1217chr10:24508838chr1:28220617ENST00000376454+2211794_1905118.01944.0Compositional biasSer-rich
HgeneKIAA1217chr10:24508838chr1:28220617ENST00000376454+221295_364118.01944.0Compositional biasPro-rich
HgeneKIAA1217chr10:24508838chr1:28220617ENST00000396445+1131794_19050907.0Compositional biasSer-rich
HgeneKIAA1217chr10:24508838chr1:28220617ENST00000396445+113295_3640907.0Compositional biasPro-rich
HgeneKIAA1217chr10:24508838chr1:28220617ENST00000396446+1121794_19050867.0Compositional biasSer-rich
HgeneKIAA1217chr10:24508838chr1:28220617ENST00000396446+112295_3640867.0Compositional biasPro-rich
HgeneKIAA1217chr10:24508838chr1:28220617ENST00000458595+2181794_1905118.01350.0Compositional biasSer-rich
HgeneKIAA1217chr10:24508838chr1:28220617ENST00000458595+218295_364118.01350.0Compositional biasPro-rich
TgeneRPA2chr10:24508838chr1:28220617ENST0000031343358127_145299.0359.0Compositional biasNote=Arg/Lys-rich (basic)
TgeneRPA2chr10:24508838chr1:28220617ENST00000313433581_29299.0359.0Compositional biasNote=Gly/Ser-rich
TgeneRPA2chr10:24508838chr1:28220617ENST0000031343358247_270299.0359.0Compositional biasNote=Asp/Glu-rich (acidic)
TgeneRPA2chr10:24508838chr1:28220617ENST000003134335837_45299.0359.0Compositional biasNote=Arg/Lys-rich (basic)
TgeneRPA2chr10:24508838chr1:28220617ENST000003134335895_123299.0359.0Compositional biasNote=Asp/Glu-rich (acidic)
TgeneRPA2chr10:24508838chr1:28220617ENST0000037390969127_145219.0279.0Compositional biasNote=Arg/Lys-rich (basic)
TgeneRPA2chr10:24508838chr1:28220617ENST00000373909691_29219.0279.0Compositional biasNote=Gly/Ser-rich
TgeneRPA2chr10:24508838chr1:28220617ENST000003739096937_45219.0279.0Compositional biasNote=Arg/Lys-rich (basic)
TgeneRPA2chr10:24508838chr1:28220617ENST000003739096995_123219.0279.0Compositional biasNote=Asp/Glu-rich (acidic)
TgeneRPA2chr10:24508838chr1:28220617ENST0000037391269127_145211.0271.0Compositional biasNote=Arg/Lys-rich (basic)
TgeneRPA2chr10:24508838chr1:28220617ENST00000373912691_29211.0271.0Compositional biasNote=Gly/Ser-rich
TgeneRPA2chr10:24508838chr1:28220617ENST000003739126937_45211.0271.0Compositional biasNote=Arg/Lys-rich (basic)
TgeneRPA2chr10:24508838chr1:28220617ENST000003739126995_123211.0271.0Compositional biasNote=Asp/Glu-rich (acidic)
TgeneRPA2chr10:24508838chr1:28220617ENST000003134335874_148299.0359.0DNA bindingNote=OB
TgeneRPA2chr10:24508838chr1:28220617ENST000003739096974_148219.0279.0DNA bindingNote=OB
TgeneRPA2chr10:24508838chr1:28220617ENST000003739126974_148211.0271.0DNA bindingNote=OB


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Fusion Gene Sequence for KIAA1217-RPA2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000376462_ENST00000373912_TCGA-HU-A4GC-11A_KIAA1217_chr10_24508838_+_RPA2_chr1_28220617_length(transcript)=1742nt_BP=923nt
GGAGAGGGCTGCGCGCTTCTCGCCAAGCAAGCGGGAGGCGCACTGGGGCCGCCGCCGTTCCCGCGCTCCTCCCTCTCCTCTGCACCCACT
GTCACGCTACCCGCCCGCGGGGGAGCCTCGAGAGCCTCCAGGTGAATTGAAAGTCGTTTCCGGGGGAGGACGGAGAGGGTGCTGCAGTCC
TGGCATGCCCTGAAACTGCAAGTCGGGCAGAAACGACCCGGCGGAGGAGCAGGGCGCGCAGCGCCCTGCGCAGCATCCCCGGGCTGCCAG
AAGAGGCCACCACTCGGCTGGCAGCCGCGAGCGGCGGCCGAACCTCGGCCCCAGACTCGGGCCCCCGGCACGCTCGCCCGGGAGATACCC
CTTCCCCCTCTTGCGCATTTCGCAGCTGCGCTGGTGTGGGGCATGAGAGCGAGGTGGCTCCAGGTCTCCGCGGAGCAGCTGCCAGTGGGA
GAGCGAGGAGAGGCGAGGGGGCGGCAGCCTCGGCCCGAAACGGAGATCCTGGGGTCCTAAATTTGTGGCCGATTGCACTGTGTCCTGGAG
ACGGAGTGGAACCACAGCCCAGAGCCCCTGGGAATCATCCCTGAAAGACTGCATTACTTCTCCATGGAGTCTTCCTCCTCCTGCTTATTT
TCTTTTTGGAACAAGGCAAAGGCAATCTGCATGTAACATCACCAGAAGATGCAGAATGCCGCAGAACCAAGGAACGCCTTTCTAATGGAA
ACAGTCGTGGTTCAGTTTCCAAGTCTTCCCGCAATATCCCAAGGAGACACACCCTAGGGGGGCCCCGAAGTTCCAAGGAAATACTGGGAA
TGCAAACATCTGAGATGGATCGGAAGAGAGAAGCGTTCCTAGAACATCTGAAGCAGAAGTACCCCCACCACGCCTCTGCAATCATGGGTC
ACCAAGAGAGGCTGAGAGACCAGGTGTTGAATTTGATTAAGGCTTGTCCAAGACCTGAAGGGTTGAACTTTCAGGATCTCAAGAACCAGC
TGAAACACATGTCTGTATCCTCAATCAAGCAAGCTGTGGATTTTCTGAGCAATGAGGGGCACATCTATTCTACTGTGGATGATGACCATT
TTAAATCCACAGATGCAGAATAACTGGATCTAACTGGGTACCTGAGATATTTTACAGCTGGACCTAGTTTCACAATCTGTTGTCTCCAGC
TCTGCATATGTCTGGCCAGGGGGCTTCTAGGAAGTAGGTTTCATCTATCAAATGTCTCCTCTGACTTCCTTTTGAAACTTACTGCTCTTC
TGTTTTATTTTGTTTTGTTTGAAGCTCAGAGGGAGATGGGCAATTGACAGGGATGCAATCCAGGGTGGGATTTCTTGAGGAAGTTACAAA
TAAGCTTGTTACAACATCAAGATAGATGGAATTGGAAGGATGCTACCAGGAGAGTACTTACATAGTGCTCAGGAGTTTCTCTTCTTAAAA
TGTTTACTGCTGAAAGATGAGCAGGACCAGGGCGTTATAGGCAGAGCCCTAGCCGAGAAACCTGCTGGCCTCTGCCTGTTTTCATTTCCC
ACTTTGGTTGTGTGGCATTACTTTCAGAATTGCACTTTCCTGCTTGTCATGACTTTTTGACACACTTGCCATGACGTGTGTTTCTGTGAA
CATGAAGTTCTGCGGTAGTGCCTCCAGGGGCAGAGGAAAAGAAGAAGTGTTACTGCATTTTGTACAAAATAAATACAGTCATATGTTTAA

>In-frame_ENST00000376462_ENST00000373912_TCGA-HU-A4GC-11A_KIAA1217_chr10_24508838_+_RPA2_chr1_28220617_length(amino acids)=160AA_start in transcript=620_stop in transcript=1102
MLIFFLEQGKGNLHVTSPEDAECRRTKERLSNGNSRGSVSKSSRNIPRRHTLGGPRSSKEILGMQTSEMDRKREAFLEHLKQKYPHHASA

--------------------------------------------------------------
>In-frame_ENST00000376462_ENST00000373909_TCGA-HU-A4GC-11A_KIAA1217_chr10_24508838_+_RPA2_chr1_28220617_length(transcript)=1342nt_BP=923nt
GGAGAGGGCTGCGCGCTTCTCGCCAAGCAAGCGGGAGGCGCACTGGGGCCGCCGCCGTTCCCGCGCTCCTCCCTCTCCTCTGCACCCACT
GTCACGCTACCCGCCCGCGGGGGAGCCTCGAGAGCCTCCAGGTGAATTGAAAGTCGTTTCCGGGGGAGGACGGAGAGGGTGCTGCAGTCC
TGGCATGCCCTGAAACTGCAAGTCGGGCAGAAACGACCCGGCGGAGGAGCAGGGCGCGCAGCGCCCTGCGCAGCATCCCCGGGCTGCCAG
AAGAGGCCACCACTCGGCTGGCAGCCGCGAGCGGCGGCCGAACCTCGGCCCCAGACTCGGGCCCCCGGCACGCTCGCCCGGGAGATACCC
CTTCCCCCTCTTGCGCATTTCGCAGCTGCGCTGGTGTGGGGCATGAGAGCGAGGTGGCTCCAGGTCTCCGCGGAGCAGCTGCCAGTGGGA
GAGCGAGGAGAGGCGAGGGGGCGGCAGCCTCGGCCCGAAACGGAGATCCTGGGGTCCTAAATTTGTGGCCGATTGCACTGTGTCCTGGAG
ACGGAGTGGAACCACAGCCCAGAGCCCCTGGGAATCATCCCTGAAAGACTGCATTACTTCTCCATGGAGTCTTCCTCCTCCTGCTTATTT
TCTTTTTGGAACAAGGCAAAGGCAATCTGCATGTAACATCACCAGAAGATGCAGAATGCCGCAGAACCAAGGAACGCCTTTCTAATGGAA
ACAGTCGTGGTTCAGTTTCCAAGTCTTCCCGCAATATCCCAAGGAGACACACCCTAGGGGGGCCCCGAAGTTCCAAGGAAATACTGGGAA
TGCAAACATCTGAGATGGATCGGAAGAGAGAAGCGTTCCTAGAACATCTGAAGCAGAAGTACCCCCACCACGCCTCTGCAATCATGGGTC
ACCAAGAGAGGCTGAGAGACCAGGTGTTGAATTTGATTAAGGCTTGTCCAAGACCTGAAGGGTTGAACTTTCAGGATCTCAAGAACCAGC
TGAAACACATGTCTGTATCCTCAATCAAGCAAGCTGTGGATTTTCTGAGCAATGAGGGGCACATCTATTCTACTGTGGATGATGACCATT
TTAAATCCACAGATGCAGAATAACTGGATCTAACTGGGTACCTGAGATATTTTACAGCTGGACCTAGTTTCACAATCTGTTGTCTCCAGC
TCTGCATATGTCTGGCCAGGGGGCTTCTAGGAAGTAGGTTTCATCTATCAAATGTCTCCTCTGACTTCCTTTTGAAACTTACTGCTCTTC

>In-frame_ENST00000376462_ENST00000373909_TCGA-HU-A4GC-11A_KIAA1217_chr10_24508838_+_RPA2_chr1_28220617_length(amino acids)=165AA_start in transcript=593_stop in transcript=96
MQSFRDDSQGLWAVVPLRLQDTVQSATNLGPQDLRFGPRLPPPRLSSLSHWQLLRGDLEPPRSHAPHQRSCEMRKRGKGYLPGERAGGPS

--------------------------------------------------------------
>In-frame_ENST00000376462_ENST00000313433_TCGA-HU-A4GC-11A_KIAA1217_chr10_24508838_+_RPA2_chr1_28220617_length(transcript)=1193nt_BP=923nt
GGAGAGGGCTGCGCGCTTCTCGCCAAGCAAGCGGGAGGCGCACTGGGGCCGCCGCCGTTCCCGCGCTCCTCCCTCTCCTCTGCACCCACT
GTCACGCTACCCGCCCGCGGGGGAGCCTCGAGAGCCTCCAGGTGAATTGAAAGTCGTTTCCGGGGGAGGACGGAGAGGGTGCTGCAGTCC
TGGCATGCCCTGAAACTGCAAGTCGGGCAGAAACGACCCGGCGGAGGAGCAGGGCGCGCAGCGCCCTGCGCAGCATCCCCGGGCTGCCAG
AAGAGGCCACCACTCGGCTGGCAGCCGCGAGCGGCGGCCGAACCTCGGCCCCAGACTCGGGCCCCCGGCACGCTCGCCCGGGAGATACCC
CTTCCCCCTCTTGCGCATTTCGCAGCTGCGCTGGTGTGGGGCATGAGAGCGAGGTGGCTCCAGGTCTCCGCGGAGCAGCTGCCAGTGGGA
GAGCGAGGAGAGGCGAGGGGGCGGCAGCCTCGGCCCGAAACGGAGATCCTGGGGTCCTAAATTTGTGGCCGATTGCACTGTGTCCTGGAG
ACGGAGTGGAACCACAGCCCAGAGCCCCTGGGAATCATCCCTGAAAGACTGCATTACTTCTCCATGGAGTCTTCCTCCTCCTGCTTATTT
TCTTTTTGGAACAAGGCAAAGGCAATCTGCATGTAACATCACCAGAAGATGCAGAATGCCGCAGAACCAAGGAACGCCTTTCTAATGGAA
ACAGTCGTGGTTCAGTTTCCAAGTCTTCCCGCAATATCCCAAGGAGACACACCCTAGGGGGGCCCCGAAGTTCCAAGGAAATACTGGGAA
TGCAAACATCTGAGATGGATCGGAAGAGAGAAGCGTTCCTAGAACATCTGAAGCAGAAGTACCCCCACCACGCCTCTGCAATCATGGGTC
ACCAAGAGAGGCTGAGAGACCAGGTGTTGAATTTGATTAAGGCTTGTCCAAGACCTGAAGGGTTGAACTTTCAGGATCTCAAGAACCAGC
TGAAACACATGTCTGTATCCTCAATCAAGCAAGCTGTGGATTTTCTGAGCAATGAGGGGCACATCTATTCTACTGTGGATGATGACCATT
TTAAATCCACAGATGCAGAATAACTGGATCTAACTGGGTACCTGAGATATTTTACAGCTGGACCTAGTTTCACAATCTGTTGTCTCCAGC

>In-frame_ENST00000376462_ENST00000313433_TCGA-HU-A4GC-11A_KIAA1217_chr10_24508838_+_RPA2_chr1_28220617_length(amino acids)=160AA_start in transcript=620_stop in transcript=1102
MLIFFLEQGKGNLHVTSPEDAECRRTKERLSNGNSRGSVSKSSRNIPRRHTLGGPRSSKEILGMQTSEMDRKREAFLEHLKQKYPHHASA

--------------------------------------------------------------
>In-frame_ENST00000458595_ENST00000373912_TCGA-HU-A4GC-11A_KIAA1217_chr10_24508838_+_RPA2_chr1_28220617_length(transcript)=1576nt_BP=757nt
AGAGCCTCGGTGGTTTGCAGCAGTGGAACCAGGCAGGCCCAGTTGTGGGTAGGAGAGGCCGTCACCTGTTGAGGCCTCCCCCCCACACCC
CCGCATCGCCCTGCCCTGGCAGAGCCCAGCCCCCAGTCCCCGGAGAGCGCGCCTGAGGACGGACGGACGGACGGACGGACAGACCTAGGG
ACGGAGGGCCAGGGGCAGGGGAGATCCAAGAGGCCCCGCGCTGGAATGCAGTTTTCTCGGGCGAGGGAGACTTTGCACCGGAGTGGAAAA
TAGTTTGGGGTGGGGTTTCGCACCGTCCCCTCCTCCCCAGCCCCGGGCCCCCTCCCAGGCGCTTTCTGGGAGCTTTTAGAACTGCGCTCT
GAAGTTTCCAGAGAGCGAGGAGCTTTTGCGGCAGGCAGAGACAATGGAAGAAAATGAAAGCCAGAAATGTGAGCCGTGCCTTCCTTACTC
AGCAGACAGAAGACAGATGCAGGAACAAGGCAAAGGCAATCTGCATGTAACATCACCAGAAGATGCAGAATGCCGCAGAACCAAGGAACG
CCTTTCTAATGGAAACAGTCGTGGTTCAGTTTCCAAGTCTTCCCGCAATATCCCAAGGAGACACACCCTAGGGGGGCCCCGAAGTTCCAA
GGAAATACTGGGAATGCAAACATCTGAGATGGATCGGAAGAGAGAAGCGTTCCTAGAACATCTGAAGCAGAAGTACCCCCACCACGCCTC
TGCAATCATGGGTCACCAAGAGAGGCTGAGAGACCAGGTGTTGAATTTGATTAAGGCTTGTCCAAGACCTGAAGGGTTGAACTTTCAGGA
TCTCAAGAACCAGCTGAAACACATGTCTGTATCCTCAATCAAGCAAGCTGTGGATTTTCTGAGCAATGAGGGGCACATCTATTCTACTGT
GGATGATGACCATTTTAAATCCACAGATGCAGAATAACTGGATCTAACTGGGTACCTGAGATATTTTACAGCTGGACCTAGTTTCACAAT
CTGTTGTCTCCAGCTCTGCATATGTCTGGCCAGGGGGCTTCTAGGAAGTAGGTTTCATCTATCAAATGTCTCCTCTGACTTCCTTTTGAA
ACTTACTGCTCTTCTGTTTTATTTTGTTTTGTTTGAAGCTCAGAGGGAGATGGGCAATTGACAGGGATGCAATCCAGGGTGGGATTTCTT
GAGGAAGTTACAAATAAGCTTGTTACAACATCAAGATAGATGGAATTGGAAGGATGCTACCAGGAGAGTACTTACATAGTGCTCAGGAGT
TTCTCTTCTTAAAATGTTTACTGCTGAAAGATGAGCAGGACCAGGGCGTTATAGGCAGAGCCCTAGCCGAGAAACCTGCTGGCCTCTGCC
TGTTTTCATTTCCCACTTTGGTTGTGTGGCATTACTTTCAGAATTGCACTTTCCTGCTTGTCATGACTTTTTGACACACTTGCCATGACG
TGTGTTTCTGTGAACATGAAGTTCTGCGGTAGTGCCTCCAGGGGCAGAGGAAAAGAAGAAGTGTTACTGCATTTTGTACAAAATAAATAC

>In-frame_ENST00000458595_ENST00000373912_TCGA-HU-A4GC-11A_KIAA1217_chr10_24508838_+_RPA2_chr1_28220617_length(amino acids)=192AA_start in transcript=358_stop in transcript=936
MKFPESEELLRQAETMEENESQKCEPCLPYSADRRQMQEQGKGNLHVTSPEDAECRRTKERLSNGNSRGSVSKSSRNIPRRHTLGGPRSS
KEILGMQTSEMDRKREAFLEHLKQKYPHHASAIMGHQERLRDQVLNLIKACPRPEGLNFQDLKNQLKHMSVSSIKQAVDFLSNEGHIYST

--------------------------------------------------------------
>In-frame_ENST00000458595_ENST00000373909_TCGA-HU-A4GC-11A_KIAA1217_chr10_24508838_+_RPA2_chr1_28220617_length(transcript)=1176nt_BP=757nt
AGAGCCTCGGTGGTTTGCAGCAGTGGAACCAGGCAGGCCCAGTTGTGGGTAGGAGAGGCCGTCACCTGTTGAGGCCTCCCCCCCACACCC
CCGCATCGCCCTGCCCTGGCAGAGCCCAGCCCCCAGTCCCCGGAGAGCGCGCCTGAGGACGGACGGACGGACGGACGGACAGACCTAGGG
ACGGAGGGCCAGGGGCAGGGGAGATCCAAGAGGCCCCGCGCTGGAATGCAGTTTTCTCGGGCGAGGGAGACTTTGCACCGGAGTGGAAAA
TAGTTTGGGGTGGGGTTTCGCACCGTCCCCTCCTCCCCAGCCCCGGGCCCCCTCCCAGGCGCTTTCTGGGAGCTTTTAGAACTGCGCTCT
GAAGTTTCCAGAGAGCGAGGAGCTTTTGCGGCAGGCAGAGACAATGGAAGAAAATGAAAGCCAGAAATGTGAGCCGTGCCTTCCTTACTC
AGCAGACAGAAGACAGATGCAGGAACAAGGCAAAGGCAATCTGCATGTAACATCACCAGAAGATGCAGAATGCCGCAGAACCAAGGAACG
CCTTTCTAATGGAAACAGTCGTGGTTCAGTTTCCAAGTCTTCCCGCAATATCCCAAGGAGACACACCCTAGGGGGGCCCCGAAGTTCCAA
GGAAATACTGGGAATGCAAACATCTGAGATGGATCGGAAGAGAGAAGCGTTCCTAGAACATCTGAAGCAGAAGTACCCCCACCACGCCTC
TGCAATCATGGGTCACCAAGAGAGGCTGAGAGACCAGGTGTTGAATTTGATTAAGGCTTGTCCAAGACCTGAAGGGTTGAACTTTCAGGA
TCTCAAGAACCAGCTGAAACACATGTCTGTATCCTCAATCAAGCAAGCTGTGGATTTTCTGAGCAATGAGGGGCACATCTATTCTACTGT
GGATGATGACCATTTTAAATCCACAGATGCAGAATAACTGGATCTAACTGGGTACCTGAGATATTTTACAGCTGGACCTAGTTTCACAAT
CTGTTGTCTCCAGCTCTGCATATGTCTGGCCAGGGGGCTTCTAGGAAGTAGGTTTCATCTATCAAATGTCTCCTCTGACTTCCTTTTGAA
ACTTACTGCTCTTCTGTTTTATTTTGTTTTGTTTGAAGCTCAGAGGGAGATGGGCAATTGACAGGGATGCAATCCAGGGTGGGATTTCTT

>In-frame_ENST00000458595_ENST00000373909_TCGA-HU-A4GC-11A_KIAA1217_chr10_24508838_+_RPA2_chr1_28220617_length(amino acids)=192AA_start in transcript=358_stop in transcript=936
MKFPESEELLRQAETMEENESQKCEPCLPYSADRRQMQEQGKGNLHVTSPEDAECRRTKERLSNGNSRGSVSKSSRNIPRRHTLGGPRSS
KEILGMQTSEMDRKREAFLEHLKQKYPHHASAIMGHQERLRDQVLNLIKACPRPEGLNFQDLKNQLKHMSVSSIKQAVDFLSNEGHIYST

--------------------------------------------------------------
>In-frame_ENST00000458595_ENST00000313433_TCGA-HU-A4GC-11A_KIAA1217_chr10_24508838_+_RPA2_chr1_28220617_length(transcript)=1027nt_BP=757nt
AGAGCCTCGGTGGTTTGCAGCAGTGGAACCAGGCAGGCCCAGTTGTGGGTAGGAGAGGCCGTCACCTGTTGAGGCCTCCCCCCCACACCC
CCGCATCGCCCTGCCCTGGCAGAGCCCAGCCCCCAGTCCCCGGAGAGCGCGCCTGAGGACGGACGGACGGACGGACGGACAGACCTAGGG
ACGGAGGGCCAGGGGCAGGGGAGATCCAAGAGGCCCCGCGCTGGAATGCAGTTTTCTCGGGCGAGGGAGACTTTGCACCGGAGTGGAAAA
TAGTTTGGGGTGGGGTTTCGCACCGTCCCCTCCTCCCCAGCCCCGGGCCCCCTCCCAGGCGCTTTCTGGGAGCTTTTAGAACTGCGCTCT
GAAGTTTCCAGAGAGCGAGGAGCTTTTGCGGCAGGCAGAGACAATGGAAGAAAATGAAAGCCAGAAATGTGAGCCGTGCCTTCCTTACTC
AGCAGACAGAAGACAGATGCAGGAACAAGGCAAAGGCAATCTGCATGTAACATCACCAGAAGATGCAGAATGCCGCAGAACCAAGGAACG
CCTTTCTAATGGAAACAGTCGTGGTTCAGTTTCCAAGTCTTCCCGCAATATCCCAAGGAGACACACCCTAGGGGGGCCCCGAAGTTCCAA
GGAAATACTGGGAATGCAAACATCTGAGATGGATCGGAAGAGAGAAGCGTTCCTAGAACATCTGAAGCAGAAGTACCCCCACCACGCCTC
TGCAATCATGGGTCACCAAGAGAGGCTGAGAGACCAGGTGTTGAATTTGATTAAGGCTTGTCCAAGACCTGAAGGGTTGAACTTTCAGGA
TCTCAAGAACCAGCTGAAACACATGTCTGTATCCTCAATCAAGCAAGCTGTGGATTTTCTGAGCAATGAGGGGCACATCTATTCTACTGT
GGATGATGACCATTTTAAATCCACAGATGCAGAATAACTGGATCTAACTGGGTACCTGAGATATTTTACAGCTGGACCTAGTTTCACAAT

>In-frame_ENST00000458595_ENST00000313433_TCGA-HU-A4GC-11A_KIAA1217_chr10_24508838_+_RPA2_chr1_28220617_length(amino acids)=192AA_start in transcript=358_stop in transcript=936
MKFPESEELLRQAETMEENESQKCEPCLPYSADRRQMQEQGKGNLHVTSPEDAECRRTKERLSNGNSRGSVSKSSRNIPRRHTLGGPRSS
KEILGMQTSEMDRKREAFLEHLKQKYPHHASAIMGHQERLRDQVLNLIKACPRPEGLNFQDLKNQLKHMSVSSIKQAVDFLSNEGHIYST

--------------------------------------------------------------
>In-frame_ENST00000376454_ENST00000373912_TCGA-HU-A4GC-11A_KIAA1217_chr10_24508838_+_RPA2_chr1_28220617_length(transcript)=1203nt_BP=384nt
AGCGAGGAGCTTTTGCGGCAGGCAGAGACAATGGAAGAAAATGAAAGCCAGAAATGTGAGCCGTGCCTTCCTTACTCAGCAGACAGAAGA
CAGATGCAGGAACAAGGCAAAGGCAATCTGCATGTAACATCACCAGAAGATGCAGAATGCCGCAGAACCAAGGAACGCCTTTCTAATGGA
AACAGTCGTGGTTCAGTTTCCAAGTCTTCCCGCAATATCCCAAGGAGACACACCCTAGGGGGGCCCCGAAGTTCCAAGGAAATACTGGGA
ATGCAAACATCTGAGATGGATCGGAAGAGAGAAGCGTTCCTAGAACATCTGAAGCAGAAGTACCCCCACCACGCCTCTGCAATCATGGGT
CACCAAGAGAGGCTGAGAGACCAGGTGTTGAATTTGATTAAGGCTTGTCCAAGACCTGAAGGGTTGAACTTTCAGGATCTCAAGAACCAG
CTGAAACACATGTCTGTATCCTCAATCAAGCAAGCTGTGGATTTTCTGAGCAATGAGGGGCACATCTATTCTACTGTGGATGATGACCAT
TTTAAATCCACAGATGCAGAATAACTGGATCTAACTGGGTACCTGAGATATTTTACAGCTGGACCTAGTTTCACAATCTGTTGTCTCCAG
CTCTGCATATGTCTGGCCAGGGGGCTTCTAGGAAGTAGGTTTCATCTATCAAATGTCTCCTCTGACTTCCTTTTGAAACTTACTGCTCTT
CTGTTTTATTTTGTTTTGTTTGAAGCTCAGAGGGAGATGGGCAATTGACAGGGATGCAATCCAGGGTGGGATTTCTTGAGGAAGTTACAA
ATAAGCTTGTTACAACATCAAGATAGATGGAATTGGAAGGATGCTACCAGGAGAGTACTTACATAGTGCTCAGGAGTTTCTCTTCTTAAA
ATGTTTACTGCTGAAAGATGAGCAGGACCAGGGCGTTATAGGCAGAGCCCTAGCCGAGAAACCTGCTGGCCTCTGCCTGTTTTCATTTCC
CACTTTGGTTGTGTGGCATTACTTTCAGAATTGCACTTTCCTGCTTGTCATGACTTTTTGACACACTTGCCATGACGTGTGTTTCTGTGA
ACATGAAGTTCTGCGGTAGTGCCTCCAGGGGCAGAGGAAAAGAAGAAGTGTTACTGCATTTTGTACAAAATAAATACAGTCATATGTTTA

>In-frame_ENST00000376454_ENST00000373912_TCGA-HU-A4GC-11A_KIAA1217_chr10_24508838_+_RPA2_chr1_28220617_length(amino acids)=183AA_start in transcript=12_stop in transcript=563
MRQAETMEENESQKCEPCLPYSADRRQMQEQGKGNLHVTSPEDAECRRTKERLSNGNSRGSVSKSSRNIPRRHTLGGPRSSKEILGMQTS
EMDRKREAFLEHLKQKYPHHASAIMGHQERLRDQVLNLIKACPRPEGLNFQDLKNQLKHMSVSSIKQAVDFLSNEGHIYSTVDDDHFKST

--------------------------------------------------------------
>In-frame_ENST00000376454_ENST00000373909_TCGA-HU-A4GC-11A_KIAA1217_chr10_24508838_+_RPA2_chr1_28220617_length(transcript)=803nt_BP=384nt
AGCGAGGAGCTTTTGCGGCAGGCAGAGACAATGGAAGAAAATGAAAGCCAGAAATGTGAGCCGTGCCTTCCTTACTCAGCAGACAGAAGA
CAGATGCAGGAACAAGGCAAAGGCAATCTGCATGTAACATCACCAGAAGATGCAGAATGCCGCAGAACCAAGGAACGCCTTTCTAATGGA
AACAGTCGTGGTTCAGTTTCCAAGTCTTCCCGCAATATCCCAAGGAGACACACCCTAGGGGGGCCCCGAAGTTCCAAGGAAATACTGGGA
ATGCAAACATCTGAGATGGATCGGAAGAGAGAAGCGTTCCTAGAACATCTGAAGCAGAAGTACCCCCACCACGCCTCTGCAATCATGGGT
CACCAAGAGAGGCTGAGAGACCAGGTGTTGAATTTGATTAAGGCTTGTCCAAGACCTGAAGGGTTGAACTTTCAGGATCTCAAGAACCAG
CTGAAACACATGTCTGTATCCTCAATCAAGCAAGCTGTGGATTTTCTGAGCAATGAGGGGCACATCTATTCTACTGTGGATGATGACCAT
TTTAAATCCACAGATGCAGAATAACTGGATCTAACTGGGTACCTGAGATATTTTACAGCTGGACCTAGTTTCACAATCTGTTGTCTCCAG
CTCTGCATATGTCTGGCCAGGGGGCTTCTAGGAAGTAGGTTTCATCTATCAAATGTCTCCTCTGACTTCCTTTTGAAACTTACTGCTCTT

>In-frame_ENST00000376454_ENST00000373909_TCGA-HU-A4GC-11A_KIAA1217_chr10_24508838_+_RPA2_chr1_28220617_length(amino acids)=183AA_start in transcript=12_stop in transcript=563
MRQAETMEENESQKCEPCLPYSADRRQMQEQGKGNLHVTSPEDAECRRTKERLSNGNSRGSVSKSSRNIPRRHTLGGPRSSKEILGMQTS
EMDRKREAFLEHLKQKYPHHASAIMGHQERLRDQVLNLIKACPRPEGLNFQDLKNQLKHMSVSSIKQAVDFLSNEGHIYSTVDDDHFKST

--------------------------------------------------------------
>In-frame_ENST00000376454_ENST00000313433_TCGA-HU-A4GC-11A_KIAA1217_chr10_24508838_+_RPA2_chr1_28220617_length(transcript)=654nt_BP=384nt
AGCGAGGAGCTTTTGCGGCAGGCAGAGACAATGGAAGAAAATGAAAGCCAGAAATGTGAGCCGTGCCTTCCTTACTCAGCAGACAGAAGA
CAGATGCAGGAACAAGGCAAAGGCAATCTGCATGTAACATCACCAGAAGATGCAGAATGCCGCAGAACCAAGGAACGCCTTTCTAATGGA
AACAGTCGTGGTTCAGTTTCCAAGTCTTCCCGCAATATCCCAAGGAGACACACCCTAGGGGGGCCCCGAAGTTCCAAGGAAATACTGGGA
ATGCAAACATCTGAGATGGATCGGAAGAGAGAAGCGTTCCTAGAACATCTGAAGCAGAAGTACCCCCACCACGCCTCTGCAATCATGGGT
CACCAAGAGAGGCTGAGAGACCAGGTGTTGAATTTGATTAAGGCTTGTCCAAGACCTGAAGGGTTGAACTTTCAGGATCTCAAGAACCAG
CTGAAACACATGTCTGTATCCTCAATCAAGCAAGCTGTGGATTTTCTGAGCAATGAGGGGCACATCTATTCTACTGTGGATGATGACCAT
TTTAAATCCACAGATGCAGAATAACTGGATCTAACTGGGTACCTGAGATATTTTACAGCTGGACCTAGTTTCACAATCTGTTGTCTCCAG

>In-frame_ENST00000376454_ENST00000313433_TCGA-HU-A4GC-11A_KIAA1217_chr10_24508838_+_RPA2_chr1_28220617_length(amino acids)=183AA_start in transcript=12_stop in transcript=563
MRQAETMEENESQKCEPCLPYSADRRQMQEQGKGNLHVTSPEDAECRRTKERLSNGNSRGSVSKSSRNIPRRHTLGGPRSSKEILGMQTS
EMDRKREAFLEHLKQKYPHHASAIMGHQERLRDQVLNLIKACPRPEGLNFQDLKNQLKHMSVSSIKQAVDFLSNEGHIYSTVDDDHFKST

--------------------------------------------------------------
>In-frame_ENST00000376452_ENST00000373912_TCGA-HU-A4GC-11A_KIAA1217_chr10_24508838_+_RPA2_chr1_28220617_length(transcript)=1194nt_BP=375nt
CTTTTGCGGCAGGCAGAGACAATGGAAGAAAATGAAAGCCAGAAATGTGAGCCGTGCCTTCCTTACTCAGCAGACAGAAGACAGATGCAG
GAACAAGGCAAAGGCAATCTGCATGTAACATCACCAGAAGATGCAGAATGCCGCAGAACCAAGGAACGCCTTTCTAATGGAAACAGTCGT
GGTTCAGTTTCCAAGTCTTCCCGCAATATCCCAAGGAGACACACCCTAGGGGGGCCCCGAAGTTCCAAGGAAATACTGGGAATGCAAACA
TCTGAGATGGATCGGAAGAGAGAAGCGTTCCTAGAACATCTGAAGCAGAAGTACCCCCACCACGCCTCTGCAATCATGGGTCACCAAGAG
AGGCTGAGAGACCAGGTGTTGAATTTGATTAAGGCTTGTCCAAGACCTGAAGGGTTGAACTTTCAGGATCTCAAGAACCAGCTGAAACAC
ATGTCTGTATCCTCAATCAAGCAAGCTGTGGATTTTCTGAGCAATGAGGGGCACATCTATTCTACTGTGGATGATGACCATTTTAAATCC
ACAGATGCAGAATAACTGGATCTAACTGGGTACCTGAGATATTTTACAGCTGGACCTAGTTTCACAATCTGTTGTCTCCAGCTCTGCATA
TGTCTGGCCAGGGGGCTTCTAGGAAGTAGGTTTCATCTATCAAATGTCTCCTCTGACTTCCTTTTGAAACTTACTGCTCTTCTGTTTTAT
TTTGTTTTGTTTGAAGCTCAGAGGGAGATGGGCAATTGACAGGGATGCAATCCAGGGTGGGATTTCTTGAGGAAGTTACAAATAAGCTTG
TTACAACATCAAGATAGATGGAATTGGAAGGATGCTACCAGGAGAGTACTTACATAGTGCTCAGGAGTTTCTCTTCTTAAAATGTTTACT
GCTGAAAGATGAGCAGGACCAGGGCGTTATAGGCAGAGCCCTAGCCGAGAAACCTGCTGGCCTCTGCCTGTTTTCATTTCCCACTTTGGT
TGTGTGGCATTACTTTCAGAATTGCACTTTCCTGCTTGTCATGACTTTTTGACACACTTGCCATGACGTGTGTTTCTGTGAACATGAAGT
TCTGCGGTAGTGCCTCCAGGGGCAGAGGAAAAGAAGAAGTGTTACTGCATTTTGTACAAAATAAATACAGTCATATGTTTAATAAAACAG

>In-frame_ENST00000376452_ENST00000373912_TCGA-HU-A4GC-11A_KIAA1217_chr10_24508838_+_RPA2_chr1_28220617_length(amino acids)=183AA_start in transcript=3_stop in transcript=554
MRQAETMEENESQKCEPCLPYSADRRQMQEQGKGNLHVTSPEDAECRRTKERLSNGNSRGSVSKSSRNIPRRHTLGGPRSSKEILGMQTS
EMDRKREAFLEHLKQKYPHHASAIMGHQERLRDQVLNLIKACPRPEGLNFQDLKNQLKHMSVSSIKQAVDFLSNEGHIYSTVDDDHFKST

--------------------------------------------------------------
>In-frame_ENST00000376452_ENST00000373909_TCGA-HU-A4GC-11A_KIAA1217_chr10_24508838_+_RPA2_chr1_28220617_length(transcript)=794nt_BP=375nt
CTTTTGCGGCAGGCAGAGACAATGGAAGAAAATGAAAGCCAGAAATGTGAGCCGTGCCTTCCTTACTCAGCAGACAGAAGACAGATGCAG
GAACAAGGCAAAGGCAATCTGCATGTAACATCACCAGAAGATGCAGAATGCCGCAGAACCAAGGAACGCCTTTCTAATGGAAACAGTCGT
GGTTCAGTTTCCAAGTCTTCCCGCAATATCCCAAGGAGACACACCCTAGGGGGGCCCCGAAGTTCCAAGGAAATACTGGGAATGCAAACA
TCTGAGATGGATCGGAAGAGAGAAGCGTTCCTAGAACATCTGAAGCAGAAGTACCCCCACCACGCCTCTGCAATCATGGGTCACCAAGAG
AGGCTGAGAGACCAGGTGTTGAATTTGATTAAGGCTTGTCCAAGACCTGAAGGGTTGAACTTTCAGGATCTCAAGAACCAGCTGAAACAC
ATGTCTGTATCCTCAATCAAGCAAGCTGTGGATTTTCTGAGCAATGAGGGGCACATCTATTCTACTGTGGATGATGACCATTTTAAATCC
ACAGATGCAGAATAACTGGATCTAACTGGGTACCTGAGATATTTTACAGCTGGACCTAGTTTCACAATCTGTTGTCTCCAGCTCTGCATA
TGTCTGGCCAGGGGGCTTCTAGGAAGTAGGTTTCATCTATCAAATGTCTCCTCTGACTTCCTTTTGAAACTTACTGCTCTTCTGTTTTAT

>In-frame_ENST00000376452_ENST00000373909_TCGA-HU-A4GC-11A_KIAA1217_chr10_24508838_+_RPA2_chr1_28220617_length(amino acids)=183AA_start in transcript=3_stop in transcript=554
MRQAETMEENESQKCEPCLPYSADRRQMQEQGKGNLHVTSPEDAECRRTKERLSNGNSRGSVSKSSRNIPRRHTLGGPRSSKEILGMQTS
EMDRKREAFLEHLKQKYPHHASAIMGHQERLRDQVLNLIKACPRPEGLNFQDLKNQLKHMSVSSIKQAVDFLSNEGHIYSTVDDDHFKST

--------------------------------------------------------------
>In-frame_ENST00000376452_ENST00000313433_TCGA-HU-A4GC-11A_KIAA1217_chr10_24508838_+_RPA2_chr1_28220617_length(transcript)=645nt_BP=375nt
CTTTTGCGGCAGGCAGAGACAATGGAAGAAAATGAAAGCCAGAAATGTGAGCCGTGCCTTCCTTACTCAGCAGACAGAAGACAGATGCAG
GAACAAGGCAAAGGCAATCTGCATGTAACATCACCAGAAGATGCAGAATGCCGCAGAACCAAGGAACGCCTTTCTAATGGAAACAGTCGT
GGTTCAGTTTCCAAGTCTTCCCGCAATATCCCAAGGAGACACACCCTAGGGGGGCCCCGAAGTTCCAAGGAAATACTGGGAATGCAAACA
TCTGAGATGGATCGGAAGAGAGAAGCGTTCCTAGAACATCTGAAGCAGAAGTACCCCCACCACGCCTCTGCAATCATGGGTCACCAAGAG
AGGCTGAGAGACCAGGTGTTGAATTTGATTAAGGCTTGTCCAAGACCTGAAGGGTTGAACTTTCAGGATCTCAAGAACCAGCTGAAACAC
ATGTCTGTATCCTCAATCAAGCAAGCTGTGGATTTTCTGAGCAATGAGGGGCACATCTATTCTACTGTGGATGATGACCATTTTAAATCC
ACAGATGCAGAATAACTGGATCTAACTGGGTACCTGAGATATTTTACAGCTGGACCTAGTTTCACAATCTGTTGTCTCCAGCTCTGCATA

>In-frame_ENST00000376452_ENST00000313433_TCGA-HU-A4GC-11A_KIAA1217_chr10_24508838_+_RPA2_chr1_28220617_length(amino acids)=183AA_start in transcript=3_stop in transcript=554
MRQAETMEENESQKCEPCLPYSADRRQMQEQGKGNLHVTSPEDAECRRTKERLSNGNSRGSVSKSSRNIPRRHTLGGPRSSKEILGMQTS
EMDRKREAFLEHLKQKYPHHASAIMGHQERLRDQVLNLIKACPRPEGLNFQDLKNQLKHMSVSSIKQAVDFLSNEGHIYSTVDDDHFKST

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Fusion Gene PPI Analysis for KIAA1217-RPA2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
TgeneRPA2chr10:24508838chr1:28220617ENST0000031343358187_270299.0359.0RAD52%2C TIPIN%2C UNG and XPA
TgeneRPA2chr10:24508838chr1:28220617ENST0000037390969187_270219.0279.0RAD52%2C TIPIN%2C UNG and XPA
TgeneRPA2chr10:24508838chr1:28220617ENST0000037391269187_270211.0271.0RAD52%2C TIPIN%2C UNG and XPA


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for KIAA1217-RPA2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for KIAA1217-RPA2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource