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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:KIFAP3-DUSP27 (FusionGDB2 ID:42571)

Fusion Gene Summary for KIFAP3-DUSP27

check button Fusion gene summary
Fusion gene informationFusion gene name: KIFAP3-DUSP27
Fusion gene ID: 42571
HgeneTgene
Gene symbol

KIFAP3

DUSP27

Gene ID

22920

338599

Gene namekinesin associated protein 3dual specificity phosphatase and pro isomerase domain containing 1
SynonymsFLA3|KAP-1|KAP-3|KAP3|SMAP|Smg-GDS|dJ190I16.1DUSP27|FMDSP
Cytomap

1q24.2

10q22.2

Type of geneprotein-codingprotein-coding
Descriptionkinesin-associated protein 3small G protein GDP dissociation stimulatorsmg GDS-associated proteindual specificity phosphatase DUPD1atypical dual-specific protein phosphatasedual specificity phosphatase 27
Modification date2020031320200313
UniProtAcc

Q92845

.
Ensembl transtripts involved in fusion geneENST00000367765, ENST00000367767, 
ENST00000361580, ENST00000538366, 
ENST00000540905, ENST00000490550, 
ENST00000361200, ENST00000271385, 
ENST00000443333, ENST00000485151, 
Fusion gene scores* DoF score6 X 5 X 5=1501 X 1 X 1=1
# samples 61
** MAII scorelog2(6/150*10)=-1.32192809488736
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(1/1*10)=3.32192809488736
Context

PubMed: KIFAP3 [Title/Abstract] AND DUSP27 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointKIFAP3(169993559)-DUSP27(167095024), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneDUSP27

GO:0006470

protein dephosphorylation

17498703


check buttonFusion gene breakpoints across KIFAP3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across DUSP27 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-OL-A5D8-01AKIFAP3chr1

169993559

-DUSP27chr1

167095024

+


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Fusion Gene ORF analysis for KIFAP3-DUSP27

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000367765ENST00000361200KIFAP3chr1

169993559

-DUSP27chr1

167095024

+
Frame-shiftENST00000367765ENST00000271385KIFAP3chr1

169993559

-DUSP27chr1

167095024

+
Frame-shiftENST00000367765ENST00000443333KIFAP3chr1

169993559

-DUSP27chr1

167095024

+
5CDS-intronENST00000367765ENST00000485151KIFAP3chr1

169993559

-DUSP27chr1

167095024

+
Frame-shiftENST00000367767ENST00000361200KIFAP3chr1

169993559

-DUSP27chr1

167095024

+
In-frameENST00000367767ENST00000271385KIFAP3chr1

169993559

-DUSP27chr1

167095024

+
Frame-shiftENST00000367767ENST00000443333KIFAP3chr1

169993559

-DUSP27chr1

167095024

+
5CDS-intronENST00000367767ENST00000485151KIFAP3chr1

169993559

-DUSP27chr1

167095024

+
Frame-shiftENST00000361580ENST00000361200KIFAP3chr1

169993559

-DUSP27chr1

167095024

+
In-frameENST00000361580ENST00000271385KIFAP3chr1

169993559

-DUSP27chr1

167095024

+
Frame-shiftENST00000361580ENST00000443333KIFAP3chr1

169993559

-DUSP27chr1

167095024

+
5CDS-intronENST00000361580ENST00000485151KIFAP3chr1

169993559

-DUSP27chr1

167095024

+
Frame-shiftENST00000538366ENST00000361200KIFAP3chr1

169993559

-DUSP27chr1

167095024

+
Frame-shiftENST00000538366ENST00000271385KIFAP3chr1

169993559

-DUSP27chr1

167095024

+
Frame-shiftENST00000538366ENST00000443333KIFAP3chr1

169993559

-DUSP27chr1

167095024

+
5CDS-intronENST00000538366ENST00000485151KIFAP3chr1

169993559

-DUSP27chr1

167095024

+
In-frameENST00000540905ENST00000361200KIFAP3chr1

169993559

-DUSP27chr1

167095024

+
Frame-shiftENST00000540905ENST00000271385KIFAP3chr1

169993559

-DUSP27chr1

167095024

+
In-frameENST00000540905ENST00000443333KIFAP3chr1

169993559

-DUSP27chr1

167095024

+
5CDS-intronENST00000540905ENST00000485151KIFAP3chr1

169993559

-DUSP27chr1

167095024

+
intron-3CDSENST00000490550ENST00000361200KIFAP3chr1

169993559

-DUSP27chr1

167095024

+
intron-3CDSENST00000490550ENST00000271385KIFAP3chr1

169993559

-DUSP27chr1

167095024

+
intron-3CDSENST00000490550ENST00000443333KIFAP3chr1

169993559

-DUSP27chr1

167095024

+
intron-intronENST00000490550ENST00000485151KIFAP3chr1

169993559

-DUSP27chr1

167095024

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000367767KIFAP3chr1169993559-ENST00000271385DUSP27chr1167095024+3831100910173830937
ENST00000361580KIFAP3chr1169993559-ENST00000271385DUSP27chr1167095024+4070124812564069938
ENST00000540905KIFAP3chr1169993559-ENST00000361200DUSP27chr1167095024+36012582663079937
ENST00000540905KIFAP3chr1169993559-ENST00000443333DUSP27chr1167095024+36372582663079937

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000367767ENST00000271385KIFAP3chr1169993559-DUSP27chr1167095024+0.009559470.9904405
ENST00000361580ENST00000271385KIFAP3chr1169993559-DUSP27chr1167095024+0.0085600340.99143994
ENST00000540905ENST00000361200KIFAP3chr1169993559-DUSP27chr1167095024+0.0076178670.9923821
ENST00000540905ENST00000443333KIFAP3chr1169993559-DUSP27chr1167095024+0.0067056380.9932943

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Fusion Genomic Features for KIFAP3-DUSP27


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
KIFAP3chr1169993558-DUSP27chr1167095023+1.16E-101
KIFAP3chr1169993558-DUSP27chr1167095023+1.16E-101

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for KIFAP3-DUSP27


check button Go to

FGviewer for the breakpoints of chr1:169993559-chr1:167095024

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
KIFAP3

Q92845

.
FUNCTION: Involved in tethering the chromosomes to the spindle pole and in chromosome movement. Binds to the tail domain of the KIF3A/KIF3B heterodimer to form a heterotrimeric KIF3 complex and may regulate the membrane binding of this complex (By similarity). {ECO:0000250}.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneDUSP27chr1:169993559chr1:167095024ENST0000027138546891_1036218.333333333333341159.0Compositional biasNote=Ser-rich
TgeneDUSP27chr1:169993559chr1:167095024ENST0000036120046891_1036218.333333333333341159.0Compositional biasNote=Ser-rich
TgeneDUSP27chr1:169993559chr1:167095024ENST0000044333335891_1036218.333333333333341159.0Compositional biasNote=Ser-rich

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneKIFAP3chr1:169993559chr1:167095024ENST00000361580-920333_373340.0793.0RepeatNote=ARM 1
HgeneKIFAP3chr1:169993559chr1:167095024ENST00000361580-920374_412340.0793.0RepeatNote=ARM 2
HgeneKIFAP3chr1:169993559chr1:167095024ENST00000361580-920494_533340.0793.0RepeatNote=ARM 3
HgeneKIFAP3chr1:169993559chr1:167095024ENST00000361580-920578_620340.0793.0RepeatNote=ARM 4
HgeneKIFAP3chr1:169993559chr1:167095024ENST00000361580-920621_662340.0793.0RepeatNote=ARM 5
HgeneKIFAP3chr1:169993559chr1:167095024ENST00000367765-920333_373300.0753.0RepeatNote=ARM 1
HgeneKIFAP3chr1:169993559chr1:167095024ENST00000367765-920374_412300.0753.0RepeatNote=ARM 2
HgeneKIFAP3chr1:169993559chr1:167095024ENST00000367765-920494_533300.0753.0RepeatNote=ARM 3
HgeneKIFAP3chr1:169993559chr1:167095024ENST00000367765-920578_620300.0753.0RepeatNote=ARM 4
HgeneKIFAP3chr1:169993559chr1:167095024ENST00000367765-920621_662300.0753.0RepeatNote=ARM 5
HgeneKIFAP3chr1:169993559chr1:167095024ENST00000367767-819333_373296.0749.0RepeatNote=ARM 1
HgeneKIFAP3chr1:169993559chr1:167095024ENST00000367767-819374_412296.0749.0RepeatNote=ARM 2
HgeneKIFAP3chr1:169993559chr1:167095024ENST00000367767-819494_533296.0749.0RepeatNote=ARM 3
HgeneKIFAP3chr1:169993559chr1:167095024ENST00000367767-819578_620296.0749.0RepeatNote=ARM 4
HgeneKIFAP3chr1:169993559chr1:167095024ENST00000367767-819621_662296.0749.0RepeatNote=ARM 5
HgeneKIFAP3chr1:169993559chr1:167095024ENST00000538366-1021333_373262.0715.0RepeatNote=ARM 1
HgeneKIFAP3chr1:169993559chr1:167095024ENST00000538366-1021374_412262.0715.0RepeatNote=ARM 2
HgeneKIFAP3chr1:169993559chr1:167095024ENST00000538366-1021494_533262.0715.0RepeatNote=ARM 3
HgeneKIFAP3chr1:169993559chr1:167095024ENST00000538366-1021578_620262.0715.0RepeatNote=ARM 4
HgeneKIFAP3chr1:169993559chr1:167095024ENST00000538366-1021621_662262.0715.0RepeatNote=ARM 5
TgeneDUSP27chr1:169993559chr1:167095024ENST0000027138546132_280218.333333333333341159.0DomainTyrosine-protein phosphatase
TgeneDUSP27chr1:169993559chr1:167095024ENST0000036120046132_280218.333333333333341159.0DomainTyrosine-protein phosphatase
TgeneDUSP27chr1:169993559chr1:167095024ENST0000044333335132_280218.333333333333341159.0DomainTyrosine-protein phosphatase


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Fusion Gene Sequence for KIFAP3-DUSP27


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000367767_ENST00000271385_TCGA-OL-A5D8-01A_KIFAP3_chr1_169993559_-_DUSP27_chr1_167095024_length(transcript)=3831nt_BP=1009nt
TTGCAGGCCTCAGGACTGTCATCGCCTCTGGGTGTGAGGGTACTTTGGCCACCGTCCCCGGAAATAACCGCGCCTGCCTCTCAAGATACC
CCATCCTCTCCACGCCGCTGCCGCTGCCGCCATGCAAGGGGAGGACGCCAGATACCTCAAAAGCATTCGACTTAAGAGTCTCAATGCCAA
CACAGATATAACTTCCCTGGCAAGGAAGGTGGTTGAAGAATGTAAACTCATTCATCCTTCAAAACTAAATGAGGTAGAACAGCTGTTGTA
CTATCTACAGAACCGCCGTGATTCATTGTCAGGAAAAGAGAAAAAAGAAAAATCAAGCAAGCCTAAAGATCCACCTCCTTTTGAAGGAAT
GGAGATTGATGAAGTTGCTAACATTAATGACATGGATGAATATATTGAGTTATTATATGAAGATATTCCTGACAAAGTTCGGGGTTCTGC
TTTGATCCTGCAGCTTGCTCGAAATCCTGATAACTTGGAAGAACTACTATTGAATGAAACTGCCCTTGGTGCATTAGCAAGGGTCCTGAG
AGAAGACTGGAAGCAAAGTGTCGAGTTAGCTACAAACATAATTTACATCTTTTTTTGTTTCTCCAGCTTTTCTCAATTTCATGGACTTAT
TACTCACTATAAAATTGGAGCTCTGTGTATGAATATTATTGATCATGAGTTAAAAAGACATGAGCTTTGGCAAGAAGAACTCTCAAAGAA
GAAGAAAGCTGTTGATGAAGACCCTGAAAACCAAACCTTGAGAAAGGATTATGAAAAAACCTTTAAAAAGTACCAGGGGCTTGTGGTAAA
ACAGGAACAGCTATTACGAGTTGCTCTTTATTTGCTTCTGAATCTTGCTGAGGATACTCGTACCGAACTGAAAATGAGGAACAAGAACAT
AGTTCACATGTTGGTGAAAGCCCTTGATCGGGACAATTTTGAGCTGCTAATTTTAGTTGTGTCATTCTTGAAGAAACTCAGCATTTTTAT
GGAGAATAAAAATGATATGGGAAAGTCCTGGTCAGCAGCGAAATGGGCATCAGCCGGTCAGCAGTGCTGGTGGTCGCCTACCTGATGATC
TTCCACAACATGGCCATCCTGGAGGCTTTGATGACCGTGCGTAAGAAGCGGGCCATCTACCCCAATGAGGGCTTCCTGAAGCAGCTGCGG
GAGCTCAATGAGAAGTTGATGGAGGAGAGAGAAGAGGACTATGGCCGGGAGGGGGGATCAGCTGAGGCTGAGGAGGGCGAGGGCACTGGG
AGCATGCTCGGGGCCAGAGTGCACGCCCTGACGGTGGAAGAGGAGGACGACAGCGCCAGCCACCTGAGTGGCTCCTCCCTGGGGAAGGCC
ACCCAGGCCTCCAAGCCCCTCACCCTCATAGACGAGGAGGAGGAGGAGAAACTGTACGAGCAGTGGAAGAAGGGGCAGGGCCTCCTCTCA
GACAAGGTCCCCCAGGATGGAGGTGGCTGGCGCTCAGCCTCCTCTGGCCAGGGTGGGGAGGAGCTCGAGGACGAGGACGTGGAGAGGATC
ATCCAGGAGTGGCAGAGCCGAAACGAGAGGTACCAAGCAGAAGGGTACCGGAGGTGGGGAAGGGAGGAGGAGAAGGAGGAGGAGAGCGAC
GCTGGCTCCTCGGTGGGGAGGCGGCGGCGCACCCTGAGCGAGAGCAGCGCCTGGGAGAGCGTGAGCAGCCACGACATCTGGGTCCTGAAG
CAGCAGCTGGAGCTGAACCGCCCGGACCACGGCAGGAGGCGCCGCGCAGACTCGATGTCCTCGGAGAGCACCTGGGACGCATGGAACGAG
AGGCTGCTGGAGATTGAGAAGGAGGCTTCCCGGAGGTACCACGCCAAGAGCAAGAGAGAGGAGGCGGCAGACAGGAGCTCAGAAGCAGGG
AGCAGGGTGCGGGAGGATGATGAGGACAGCGTGGGCTCTGAGGCCAGTTCCTTCTACAACTTCTGCAGCAGGAACAAGGACAAGCTCACT
GCCCTGGAAAGATGGAAGATCAAGAGAATCCAATTTGGATTTCACAAGAAAGACTTGGGAGCGGGAGACAGCAGCGGTGAGCCCGGTGCA
GAGGAGGCAGTAGGGGAGAAGAACCCCTCCGACGTCAGCCTGACAGCCTACCAGGCCTGGAAGCTGAAACACCAGAAGAAGGTGGGCAGT
GAGAACAAGGAGGAGGTGGTGGAGCTCAGCAAGGGGGAGGACTCGGCCTTGGCTAAGAAGAGACAACGGAGGCTGGAGCTGCTGGAGAGA
AGCCGGCAGACGCTGGAGGAGAGCCAGTCTATGGCAAGCTGGGAGGCGGACAGCTCCACGGCCAGCGGGAGCATTCCCCTGTCTGCGTTC
TGGTCTGCAGACCCCTCAGTCAGCGCTGATGGGGACACGACGTCAGTACTGAGCACCCAGAGCCACCGCTCCCACCTGTCTCAGGCTGCA
AGCAACATAGCGGGGTGTTCAACCTCCAACCCCACCACACCCCTGCCTAACCTGCCAGTGGGGCCTGGAGACACCATTTCCATTGCCAGT
ATCCAGAACTGGATTGCCAATGTAGTCAGTGAGACCCTTGCTCAGAAGCAAAATGAAATGCTGCTGTTGTCCCGCTCACCGTCTGTTGCA
AGCATGAAGGCAGTACCAGCGGCTAGCTGCCTGGGGGATGACCAAGTCTCCATGCTTAGTGGACACAGCAGCTCCTCCTTGGGTGGCTGC
CTGTTGCCTCAGAGCCAGGCAAGACCCAGCTCTGACATGCAGTCTGTGCTGTCCTGCAACACCACACTGAGCTCACCCGCGGAAAGTTGC
AGAAGCAAAGTGAGGGGGACCAGCAAGCCCATCTTCAGCCTCTTTGCTGACAATGTGGACCTAAAGGAACTTGGCCGGAAGGAGAAGGAG
ATGCAGATGGAGCTTAGGGAGAAGATGTCTGAGTACAAAATGGAAAAGCTGGCCTCAGACAACAAACGCAGCTCCCTCTTCAAGAAGAAG
AAGGTCAAGGAAGATGAGGATGATGGTGTGGGTGATGGGGATGAGGACACTGACAGTGCCATAGGGAGCTTCCGATATTCTTCCCGCAGT
AATTCCCAGAAACCTGAAACAGACACATGCTCCTCCCTGGCTGTCTGTGATCACTATGCAAGTGGCAGCAGAGTTGGCAAAGAGATGGAT
AGCAGTATTAATAAGTGGCTCAGTGGCCTCAGGACGGAGGAAAAACCTCCTTTCCAAAGTGACTGGTCTGGAAGTTCCAGAGGGAAGTAC
ACCAGATCGTCCCTGCTCAGGGAGACAGAGTCTAAATCCTCCAGTTACAAGTTTTCCAAATCCCAGTCAGAGGAACAGGACACCTCCTCC
TACCACGAGGCAAATGGCAACTCTGTAAGAAGCACTTCACGGTTCTCATCTTCCTCCACCAGGGAGGGCAGAGAGATGCACAAGTTCTCC
AGGTCCACGTACAACGAGACCTCAAGTTCCCGAGAGGAGAGCCCAGAGCCCTACTTCTTCCGCCGGACCCCAGAGTCCTCAGAAAGGGAA
GAGTCCCCAGAACCACAGCGCCCAAATTGGGCCAGGTCCAGGGACTGGGAAGATGTGGAAGAGTCATCCAAGTCAGACTTCTCTGAATTT
GGAGCCAAGAGGAAGTTCACCCAGAGCTTTATGAGGTCTGAAGAAGAGGGAGAGAAAGAGAGGACAGAAAACAGAGAAGAAGGGAGGTTT
GCATCTGGACGGCGGTCCCAGTATCGGAGAAGCACTGACAGGGAGGAAGAGGAAGAAATGGACGATGAAGCCATCATTGCTGCTTGGAGA

>In-frame_ENST00000367767_ENST00000271385_TCGA-OL-A5D8-01A_KIFAP3_chr1_169993559_-_DUSP27_chr1_167095024_length(amino acids)=937AA_start in transcript=1017_stop in transcript=3830
MVSSEMGISRSAVLVVAYLMIFHNMAILEALMTVRKKRAIYPNEGFLKQLRELNEKLMEEREEDYGREGGSAEAEEGEGTGSMLGARVHA
LTVEEEDDSASHLSGSSLGKATQASKPLTLIDEEEEEKLYEQWKKGQGLLSDKVPQDGGGWRSASSGQGGEELEDEDVERIIQEWQSRNE
RYQAEGYRRWGREEEKEEESDAGSSVGRRRRTLSESSAWESVSSHDIWVLKQQLELNRPDHGRRRRADSMSSESTWDAWNERLLEIEKEA
SRRYHAKSKREEAADRSSEAGSRVREDDEDSVGSEASSFYNFCSRNKDKLTALERWKIKRIQFGFHKKDLGAGDSSGEPGAEEAVGEKNP
SDVSLTAYQAWKLKHQKKVGSENKEEVVELSKGEDSALAKKRQRRLELLERSRQTLEESQSMASWEADSSTASGSIPLSAFWSADPSVSA
DGDTTSVLSTQSHRSHLSQAASNIAGCSTSNPTTPLPNLPVGPGDTISIASIQNWIANVVSETLAQKQNEMLLLSRSPSVASMKAVPAAS
CLGDDQVSMLSGHSSSSLGGCLLPQSQARPSSDMQSVLSCNTTLSSPAESCRSKVRGTSKPIFSLFADNVDLKELGRKEKEMQMELREKM
SEYKMEKLASDNKRSSLFKKKKVKEDEDDGVGDGDEDTDSAIGSFRYSSRSNSQKPETDTCSSLAVCDHYASGSRVGKEMDSSINKWLSG
LRTEEKPPFQSDWSGSSRGKYTRSSLLRETESKSSSYKFSKSQSEEQDTSSYHEANGNSVRSTSRFSSSSTREGREMHKFSRSTYNETSS
SREESPEPYFFRRTPESSEREESPEPQRPNWARSRDWEDVEESSKSDFSEFGAKRKFTQSFMRSEEEGEKERTENREEGRFASGRRSQYR

--------------------------------------------------------------
>In-frame_ENST00000361580_ENST00000271385_TCGA-OL-A5D8-01A_KIFAP3_chr1_169993559_-_DUSP27_chr1_167095024_length(transcript)=4070nt_BP=1248nt
AGGCGACTCTGGGCGGGTCTGGGCCGCTCCAGTGTTTTGGGGCACAGAAGCTGTGGGAGGAGCTGGAGGCTTCACCGTGGTAACCACAGC
GCCGCTGCTGCCCCGCCTTGCAGGCCTCAGGACTGTCATCGCCTCTGGGTGTGAGGGTACTTTGGCCACCGTCCCCGGAAATAACCGCGC
CTGCCTCTCAAGATACCCCATCCTCTCCACGCCGCTGCCGCTGCCGCCATGCAAGGGGAGGACGCCAGATACCTCAAAAGGAAAGTTAAA
GGAGGGAATATAGATGTACATCCATCAGAAAAAGCACTCATTGTTCACTATGAAGTGGAAGCTACCATTCTTGGAGAAATGGGGGACCCC
ATGTTGGGAGAACGAAAAGAATGTCAAAAAATCATTCGACTTAAGAGTCTCAATGCCAACACAGATATAACTTCCCTGGCAAGGAAGGTG
GTTGAAGAATGTAAACTCATTCATCCTTCAAAACTAAATGAGGTAGAACAGCTGTTGTACTATCTACAGAACCGCCGTGATTCATTGTCA
GGAAAAGAGAAAAAAGAAAAATCAAGCAAGCCTAAAGATCCACCTCCTTTTGAAGGAATGGAGATTGATGAAGTTGCTAACATTAATGAC
ATGGATGAATATATTGAGTTATTATATGAAGATATTCCTGACAAAGTTCGGGGTTCTGCTTTGATCCTGCAGCTTGCTCGAAATCCTGAT
AACTTGGAAGAACTACTATTGAATGAAACTGCCCTTGGTGCATTAGCAAGGGTCCTGAGAGAAGACTGGAAGCAAAGTGTCGAGTTAGCT
ACAAACATAATTTACATCTTTTTTTGTTTCTCCAGCTTTTCTCAATTTCATGGACTTATTACTCACTATAAAATTGGAGCTCTGTGTATG
AATATTATTGATCATGAGTTAAAAAGACATGAGCTTTGGCAAGAAGAACTCTCAAAGAAGAAGAAAGCTGTTGATGAAGACCCTGAAAAC
CAAACCTTGAGAAAGGATTATGAAAAAACCTTTAAAAAGTACCAGGGGCTTGTGGTAAAACAGGAACAGCTATTACGAGTTGCTCTTTAT
TTGCTTCTGAATCTTGCTGAGGATACTCGTACCGAACTGAAAATGAGGAACAAGAACATAGTTCACATGTTGGTGAAAGCCCTTGATCGG
GACAATTTTGAGCTGCTAATTTTAGTTGTGTCATTCTTGAAGAAACTCAGCATTTTTATGGAGAATAAAAATGATATGGGAAAGTCCTGG
TCAGCAGCGAAATGGGCATCAGCCGGTCAGCAGTGCTGGTGGTCGCCTACCTGATGATCTTCCACAACATGGCCATCCTGGAGGCTTTGA
TGACCGTGCGTAAGAAGCGGGCCATCTACCCCAATGAGGGCTTCCTGAAGCAGCTGCGGGAGCTCAATGAGAAGTTGATGGAGGAGAGAG
AAGAGGACTATGGCCGGGAGGGGGGATCAGCTGAGGCTGAGGAGGGCGAGGGCACTGGGAGCATGCTCGGGGCCAGAGTGCACGCCCTGA
CGGTGGAAGAGGAGGACGACAGCGCCAGCCACCTGAGTGGCTCCTCCCTGGGGAAGGCCACCCAGGCCTCCAAGCCCCTCACCCTCATAG
ACGAGGAGGAGGAGGAGAAACTGTACGAGCAGTGGAAGAAGGGGCAGGGCCTCCTCTCAGACAAGGTCCCCCAGGATGGAGGTGGCTGGC
GCTCAGCCTCCTCTGGCCAGGGTGGGGAGGAGCTCGAGGACGAGGACGTGGAGAGGATCATCCAGGAGTGGCAGAGCCGAAACGAGAGGT
ACCAAGCAGAAGGGTACCGGAGGTGGGGAAGGGAGGAGGAGAAGGAGGAGGAGAGCGACGCTGGCTCCTCGGTGGGGAGGCGGCGGCGCA
CCCTGAGCGAGAGCAGCGCCTGGGAGAGCGTGAGCAGCCACGACATCTGGGTCCTGAAGCAGCAGCTGGAGCTGAACCGCCCGGACCACG
GCAGGAGGCGCCGCGCAGACTCGATGTCCTCGGAGAGCACCTGGGACGCATGGAACGAGAGGCTGCTGGAGATTGAGAAGGAGGCTTCCC
GGAGGTACCACGCCAAGAGCAAGAGAGAGGAGGCGGCAGACAGGAGCTCAGAAGCAGGGAGCAGGGTGCGGGAGGATGATGAGGACAGCG
TGGGCTCTGAGGCCAGTTCCTTCTACAACTTCTGCAGCAGGAACAAGGACAAGCTCACTGCCCTGGAAAGATGGAAGATCAAGAGAATCC
AATTTGGATTTCACAAGAAAGACTTGGGAGCGGGAGACAGCAGCGGTGAGCCCGGTGCAGAGGAGGCAGTAGGGGAGAAGAACCCCTCCG
ACGTCAGCCTGACAGCCTACCAGGCCTGGAAGCTGAAACACCAGAAGAAGGTGGGCAGTGAGAACAAGGAGGAGGTGGTGGAGCTCAGCA
AGGGGGAGGACTCGGCCTTGGCTAAGAAGAGACAACGGAGGCTGGAGCTGCTGGAGAGAAGCCGGCAGACGCTGGAGGAGAGCCAGTCTA
TGGCAAGCTGGGAGGCGGACAGCTCCACGGCCAGCGGGAGCATTCCCCTGTCTGCGTTCTGGTCTGCAGACCCCTCAGTCAGCGCTGATG
GGGACACGACGTCAGTACTGAGCACCCAGAGCCACCGCTCCCACCTGTCTCAGGCTGCAAGCAACATAGCGGGGTGTTCAACCTCCAACC
CCACCACACCCCTGCCTAACCTGCCAGTGGGGCCTGGAGACACCATTTCCATTGCCAGTATCCAGAACTGGATTGCCAATGTAGTCAGTG
AGACCCTTGCTCAGAAGCAAAATGAAATGCTGCTGTTGTCCCGCTCACCGTCTGTTGCAAGCATGAAGGCAGTACCAGCGGCTAGCTGCC
TGGGGGATGACCAAGTCTCCATGCTTAGTGGACACAGCAGCTCCTCCTTGGGTGGCTGCCTGTTGCCTCAGAGCCAGGCAAGACCCAGCT
CTGACATGCAGTCTGTGCTGTCCTGCAACACCACACTGAGCTCACCCGCGGAAAGTTGCAGAAGCAAAGTGAGGGGGACCAGCAAGCCCA
TCTTCAGCCTCTTTGCTGACAATGTGGACCTAAAGGAACTTGGCCGGAAGGAGAAGGAGATGCAGATGGAGCTTAGGGAGAAGATGTCTG
AGTACAAAATGGAAAAGCTGGCCTCAGACAACAAACGCAGCTCCCTCTTCAAGAAGAAGAAGGTCAAGGAAGATGAGGATGATGGTGTGG
GTGATGGGGATGAGGACACTGACAGTGCCATAGGGAGCTTCCGATATTCTTCCCGCAGTAATTCCCAGAAACCTGAAACAGACACATGCT
CCTCCCTGGCTGTCTGTGATCACTATGCAAGTGGCAGCAGAGTTGGCAAAGAGATGGATAGCAGTATTAATAAGTGGCTCAGTGGCCTCA
GGACGGAGGAAAAACCTCCTTTCCAAAGTGACTGGTCTGGAAGTTCCAGAGGGAAGTACACCAGATCGTCCCTGCTCAGGGAGACAGAGT
CTAAATCCTCCAGTTACAAGTTTTCCAAATCCCAGTCAGAGGAACAGGACACCTCCTCCTACCACGAGGCAAATGGCAACTCTGTAAGAA
GCACTTCACGGTTCTCATCTTCCTCCACCAGGGAGGGCAGAGAGATGCACAAGTTCTCCAGGTCCACGTACAACGAGACCTCAAGTTCCC
GAGAGGAGAGCCCAGAGCCCTACTTCTTCCGCCGGACCCCAGAGTCCTCAGAAAGGGAAGAGTCCCCAGAACCACAGCGCCCAAATTGGG
CCAGGTCCAGGGACTGGGAAGATGTGGAAGAGTCATCCAAGTCAGACTTCTCTGAATTTGGAGCCAAGAGGAAGTTCACCCAGAGCTTTA
TGAGGTCTGAAGAAGAGGGAGAGAAAGAGAGGACAGAAAACAGAGAAGAAGGGAGGTTTGCATCTGGACGGCGGTCCCAGTATCGGAGAA
GCACTGACAGGGAGGAAGAGGAAGAAATGGACGATGAAGCCATCATTGCTGCTTGGAGACGCCGGCAAGAAGAAACCAGGACCAAGCTGC

>In-frame_ENST00000361580_ENST00000271385_TCGA-OL-A5D8-01A_KIFAP3_chr1_169993559_-_DUSP27_chr1_167095024_length(amino acids)=938AA_start in transcript=1256_stop in transcript=4069
MVSSEMGISRSAVLVVAYLMIFHNMAILEALMTVRKKRAIYPNEGFLKQLRELNEKLMEEREEDYGREGGSAEAEEGEGTGSMLGARVHA
LTVEEEDDSASHLSGSSLGKATQASKPLTLIDEEEEEKLYEQWKKGQGLLSDKVPQDGGGWRSASSGQGGEELEDEDVERIIQEWQSRNE
RYQAEGYRRWGREEEKEEESDAGSSVGRRRRTLSESSAWESVSSHDIWVLKQQLELNRPDHGRRRRADSMSSESTWDAWNERLLEIEKEA
SRRYHAKSKREEAADRSSEAGSRVREDDEDSVGSEASSFYNFCSRNKDKLTALERWKIKRIQFGFHKKDLGAGDSSGEPGAEEAVGEKNP
SDVSLTAYQAWKLKHQKKVGSENKEEVVELSKGEDSALAKKRQRRLELLERSRQTLEESQSMASWEADSSTASGSIPLSAFWSADPSVSA
DGDTTSVLSTQSHRSHLSQAASNIAGCSTSNPTTPLPNLPVGPGDTISIASIQNWIANVVSETLAQKQNEMLLLSRSPSVASMKAVPAAS
CLGDDQVSMLSGHSSSSLGGCLLPQSQARPSSDMQSVLSCNTTLSSPAESCRSKVRGTSKPIFSLFADNVDLKELGRKEKEMQMELREKM
SEYKMEKLASDNKRSSLFKKKKVKEDEDDGVGDGDEDTDSAIGSFRYSSRSNSQKPETDTCSSLAVCDHYASGSRVGKEMDSSINKWLSG
LRTEEKPPFQSDWSGSSRGKYTRSSLLRETESKSSSYKFSKSQSEEQDTSSYHEANGNSVRSTSRFSSSSTREGREMHKFSRSTYNETSS
SREESPEPYFFRRTPESSEREESPEPQRPNWARSRDWEDVEESSKSDFSEFGAKRKFTQSFMRSEEEGEKERTENREEGRFASGRRSQYR

--------------------------------------------------------------
>In-frame_ENST00000540905_ENST00000361200_TCGA-OL-A5D8-01A_KIFAP3_chr1_169993559_-_DUSP27_chr1_167095024_length(transcript)=3601nt_BP=258nt
AACATAAATTTTAGAAGGACAGTATTCAACCGGCTACCTCTATCTTGGCTGTAAAGAGAAGTCTGTTTGTTTTTTCAATTTGCTCTTTAT
TTGCTTCTGAATCTTGCTGAGGATACTCGTACCGAACTGAAAATGAGGAACAAGAACATAGTTCACATGTTGGTGAAAGCCCTTGATCGG
GACAATTTTGAGCTGCTAATTTTAGTTGTGTCATTCTTGAAGAAACTCAGCATTTTTATGGAGAATAAAAATGATATGGGAAAGTCCTGG
TCAGCAGCGAAATGGGCATCAGCCGGTCAGCAGTGCTGGTGGTCGCCTACCTGATGATCTTCCACAACATGGCCATCCTGGAGGCTTTGA
TGACCGTGCGTAAGAAGCGGGCCATCTACCCCAATGAGGGCTTCCTGAAGCAGCTGCGGGAGCTCAATGAGAAGTTGATGGAGGAGAGAG
AAGAGGACTATGGCCGGGAGGGGGGATCAGCTGAGGCTGAGGAGGGCGAGGGCACTGGGAGCATGCTCGGGGCCAGAGTGCACGCCCTGA
CGGTGGAAGAGGAGGACGACAGCGCCAGCCACCTGAGTGGCTCCTCCCTGGGGAAGGCCACCCAGGCCTCCAAGCCCCTCACCCTCATAG
ACGAGGAGGAGGAGGAGAAACTGTACGAGCAGTGGAAGAAGGGGCAGGGCCTCCTCTCAGACAAGGTCCCCCAGGATGGAGGTGGCTGGC
GCTCAGCCTCCTCTGGCCAGGGTGGGGAGGAGCTCGAGGACGAGGACGTGGAGAGGATCATCCAGGAGTGGCAGAGCCGAAACGAGAGGT
ACCAAGCAGAAGGGTACCGGAGGTGGGGAAGGGAGGAGGAGAAGGAGGAGGAGAGCGACGCTGGCTCCTCGGTGGGGAGGCGGCGGCGCA
CCCTGAGCGAGAGCAGCGCCTGGGAGAGCGTGAGCAGCCACGACATCTGGGTCCTGAAGCAGCAGCTGGAGCTGAACCGCCCGGACCACG
GCAGGAGGCGCCGCGCAGACTCGATGTCCTCGGAGAGCACCTGGGACGCATGGAACGAGAGGCTGCTGGAGATTGAGAAGGAGGCTTCCC
GGAGGTACCACGCCAAGAGCAAGAGAGAGGAGGCGGCAGACAGGAGCTCAGAAGCAGGGAGCAGGGTGCGGGAGGATGATGAGGACAGCG
TGGGCTCTGAGGCCAGTTCCTTCTACAACTTCTGCAGCAGGAACAAGGACAAGCTCACTGCCCTGGAAAGATGGAAGATCAAGAGAATCC
AATTTGGATTTCACAAGAAAGACTTGGGAGCGGGAGACAGCAGCGGTGAGCCCGGTGCAGAGGAGGCAGTAGGGGAGAAGAACCCCTCCG
ACGTCAGCCTGACAGCCTACCAGGCCTGGAAGCTGAAACACCAGAAGAAGGTGGGCAGTGAGAACAAGGAGGAGGTGGTGGAGCTCAGCA
AGGGGGAGGACTCGGCCTTGGCTAAGAAGAGACAACGGAGGCTGGAGCTGCTGGAGAGAAGCCGGCAGACGCTGGAGGAGAGCCAGTCTA
TGGCAAGCTGGGAGGCGGACAGCTCCACGGCCAGCGGGAGCATTCCCCTGTCTGCGTTCTGGTCTGCAGACCCCTCAGTCAGCGCTGATG
GGGACACGACGTCAGTACTGAGCACCCAGAGCCACCGCTCCCACCTGTCTCAGGCTGCAAGCAACATAGCGGGGTGTTCAACCTCCAACC
CCACCACACCCCTGCCTAACCTGCCAGTGGGGCCTGGAGACACCATTTCCATTGCCAGTATCCAGAACTGGATTGCCAATGTAGTCAGTG
AGACCCTTGCTCAGAAGCAAAATGAAATGCTGCTGTTGTCCCGCTCACCGTCTGTTGCAAGCATGAAGGCAGTACCAGCGGCTAGCTGCC
TGGGGGATGACCAAGTCTCCATGCTTAGTGGACACAGCAGCTCCTCCTTGGGTGGCTGCCTGTTGCCTCAGAGCCAGGCAAGACCCAGCT
CTGACATGCAGTCTGTGCTGTCCTGCAACACCACACTGAGCTCACCCGCGGAAAGTTGCAGAAGCAAAGTGAGGGGGACCAGCAAGCCCA
TCTTCAGCCTCTTTGCTGACAATGTGGACCTAAAGGAACTTGGCCGGAAGGAGAAGGAGATGCAGATGGAGCTTAGGGAGAAGATGTCTG
AGTACAAAATGGAAAAGCTGGCCTCAGACAACAAACGCAGCTCCCTCTTCAAGAAGAAGAAGGTCAAGGAAGATGAGGATGATGGTGTGG
GTGATGGGGATGAGGACACTGACAGTGCCATAGGGAGCTTCCGATATTCTTCCCGCAGTAATTCCCAGAAACCTGAAACAGACACATGCT
CCTCCCTGGCTGTCTGTGATCACTATGCAAGTGGCAGCAGAGTTGGCAAAGAGATGGATAGCAGTATTAATAAGTGGCTCAGTGGCCTCA
GGACGGAGGAAAAACCTCCTTTCCAAAGTGACTGGTCTGGAAGTTCCAGAGGGAAGTACACCAGATCGTCCCTGCTCAGGGAGACAGAGT
CTAAATCCTCCAGTTACAAGTTTTCCAAATCCCAGTCAGAGGAACAGGACACCTCCTCCTACCACGAGGCAAATGGCAACTCTGTAAGAA
GCACTTCACGGTTCTCATCTTCCTCCACCAGGGAGGGCAGAGAGATGCACAAGTTCTCCAGGTCCACGTACAACGAGACCTCAAGTTCCC
GAGAGGAGAGCCCAGAGCCCTACTTCTTCCGCCGGACCCCAGAGTCCTCAGAAAGGGAAGAGTCCCCAGAACCACAGCGCCCAAATTGGG
CCAGGTCCAGGGACTGGGAAGATGTGGAAGAGTCATCCAAGTCAGACTTCTCTGAATTTGGAGCCAAGAGGAAGTTCACCCAGAGCTTTA
TGAGGTCTGAAGAAGAGGGAGAGAAAGAGAGGACAGAAAACAGAGAAGAAGGGAGGTTTGCATCTGGACGGCGGTCCCAGTATCGGAGAA
GCACTGACAGGGAGGAAGAGGAAGAAATGGACGATGAAGCCATCATTGCTGCTTGGAGACGCCGGCAAGAAGAAACCAGGACCAAGCTGC
AGAAAAGGAGGGAGGACTGAGCTGGGGAAAATCTGAGAACACTGAAAGAAACCACTCACGTTAGCATAGGGCTCAGGGCACACGTTGCCA
CCACTCATCGCAGGATGAGGATACAGAGAGGATCTTCCAGAGGGGCAGAGCCAAAATGAGAGGTACCAAGCATAAGGGCAGCAGAGGTGG
AGTAGGGAGGAGGCAAGGAGGGGGAGAACCATCAATACGAATACGAGGTCCGAATGCGGACCAACTGATACCATTTTCTGTTGCTCAGCG
CCCTCTAAGCTTTGGTGTTTCACTTAATGTATTTGGCAGTGTTCATCACAGGCTAGAGAGGTGAGCTTGGAAAAGCACTGTAGTTTGTCA
GAGACTCCAGTTTACATCCAGAAAGGCCATGAACATAGGACACGCTTCTGTCTGTAGAGGCTTCATATGAGACCCAGAAAGTCTATCCTA
TGGCAAGTCTGACCTCTCCTGGCAATGCTCAGTTCTGATTTTTTTTTTTTTAATGTTTTGAGTCTCCATTAAAAATGGTATGTTGGCAAA

>In-frame_ENST00000540905_ENST00000361200_TCGA-OL-A5D8-01A_KIFAP3_chr1_169993559_-_DUSP27_chr1_167095024_length(amino acids)=937AA_start in transcript=266_stop in transcript=3079
MVSSEMGISRSAVLVVAYLMIFHNMAILEALMTVRKKRAIYPNEGFLKQLRELNEKLMEEREEDYGREGGSAEAEEGEGTGSMLGARVHA
LTVEEEDDSASHLSGSSLGKATQASKPLTLIDEEEEEKLYEQWKKGQGLLSDKVPQDGGGWRSASSGQGGEELEDEDVERIIQEWQSRNE
RYQAEGYRRWGREEEKEEESDAGSSVGRRRRTLSESSAWESVSSHDIWVLKQQLELNRPDHGRRRRADSMSSESTWDAWNERLLEIEKEA
SRRYHAKSKREEAADRSSEAGSRVREDDEDSVGSEASSFYNFCSRNKDKLTALERWKIKRIQFGFHKKDLGAGDSSGEPGAEEAVGEKNP
SDVSLTAYQAWKLKHQKKVGSENKEEVVELSKGEDSALAKKRQRRLELLERSRQTLEESQSMASWEADSSTASGSIPLSAFWSADPSVSA
DGDTTSVLSTQSHRSHLSQAASNIAGCSTSNPTTPLPNLPVGPGDTISIASIQNWIANVVSETLAQKQNEMLLLSRSPSVASMKAVPAAS
CLGDDQVSMLSGHSSSSLGGCLLPQSQARPSSDMQSVLSCNTTLSSPAESCRSKVRGTSKPIFSLFADNVDLKELGRKEKEMQMELREKM
SEYKMEKLASDNKRSSLFKKKKVKEDEDDGVGDGDEDTDSAIGSFRYSSRSNSQKPETDTCSSLAVCDHYASGSRVGKEMDSSINKWLSG
LRTEEKPPFQSDWSGSSRGKYTRSSLLRETESKSSSYKFSKSQSEEQDTSSYHEANGNSVRSTSRFSSSSTREGREMHKFSRSTYNETSS
SREESPEPYFFRRTPESSEREESPEPQRPNWARSRDWEDVEESSKSDFSEFGAKRKFTQSFMRSEEEGEKERTENREEGRFASGRRSQYR

--------------------------------------------------------------
>In-frame_ENST00000540905_ENST00000443333_TCGA-OL-A5D8-01A_KIFAP3_chr1_169993559_-_DUSP27_chr1_167095024_length(transcript)=3637nt_BP=258nt
AACATAAATTTTAGAAGGACAGTATTCAACCGGCTACCTCTATCTTGGCTGTAAAGAGAAGTCTGTTTGTTTTTTCAATTTGCTCTTTAT
TTGCTTCTGAATCTTGCTGAGGATACTCGTACCGAACTGAAAATGAGGAACAAGAACATAGTTCACATGTTGGTGAAAGCCCTTGATCGG
GACAATTTTGAGCTGCTAATTTTAGTTGTGTCATTCTTGAAGAAACTCAGCATTTTTATGGAGAATAAAAATGATATGGGAAAGTCCTGG
TCAGCAGCGAAATGGGCATCAGCCGGTCAGCAGTGCTGGTGGTCGCCTACCTGATGATCTTCCACAACATGGCCATCCTGGAGGCTTTGA
TGACCGTGCGTAAGAAGCGGGCCATCTACCCCAATGAGGGCTTCCTGAAGCAGCTGCGGGAGCTCAATGAGAAGTTGATGGAGGAGAGAG
AAGAGGACTATGGCCGGGAGGGGGGATCAGCTGAGGCTGAGGAGGGCGAGGGCACTGGGAGCATGCTCGGGGCCAGAGTGCACGCCCTGA
CGGTGGAAGAGGAGGACGACAGCGCCAGCCACCTGAGTGGCTCCTCCCTGGGGAAGGCCACCCAGGCCTCCAAGCCCCTCACCCTCATAG
ACGAGGAGGAGGAGGAGAAACTGTACGAGCAGTGGAAGAAGGGGCAGGGCCTCCTCTCAGACAAGGTCCCCCAGGATGGAGGTGGCTGGC
GCTCAGCCTCCTCTGGCCAGGGTGGGGAGGAGCTCGAGGACGAGGACGTGGAGAGGATCATCCAGGAGTGGCAGAGCCGAAACGAGAGGT
ACCAAGCAGAAGGGTACCGGAGGTGGGGAAGGGAGGAGGAGAAGGAGGAGGAGAGCGACGCTGGCTCCTCGGTGGGGAGGCGGCGGCGCA
CCCTGAGCGAGAGCAGCGCCTGGGAGAGCGTGAGCAGCCACGACATCTGGGTCCTGAAGCAGCAGCTGGAGCTGAACCGCCCGGACCACG
GCAGGAGGCGCCGCGCAGACTCGATGTCCTCGGAGAGCACCTGGGACGCATGGAACGAGAGGCTGCTGGAGATTGAGAAGGAGGCTTCCC
GGAGGTACCACGCCAAGAGCAAGAGAGAGGAGGCGGCAGACAGGAGCTCAGAAGCAGGGAGCAGGGTGCGGGAGGATGATGAGGACAGCG
TGGGCTCTGAGGCCAGTTCCTTCTACAACTTCTGCAGCAGGAACAAGGACAAGCTCACTGCCCTGGAAAGATGGAAGATCAAGAGAATCC
AATTTGGATTTCACAAGAAAGACTTGGGAGCGGGAGACAGCAGCGGTGAGCCCGGTGCAGAGGAGGCAGTAGGGGAGAAGAACCCCTCCG
ACGTCAGCCTGACAGCCTACCAGGCCTGGAAGCTGAAACACCAGAAGAAGGTGGGCAGTGAGAACAAGGAGGAGGTGGTGGAGCTCAGCA
AGGGGGAGGACTCGGCCTTGGCTAAGAAGAGACAACGGAGGCTGGAGCTGCTGGAGAGAAGCCGGCAGACGCTGGAGGAGAGCCAGTCTA
TGGCAAGCTGGGAGGCGGACAGCTCCACGGCCAGCGGGAGCATTCCCCTGTCTGCGTTCTGGTCTGCAGACCCCTCAGTCAGCGCTGATG
GGGACACGACGTCAGTACTGAGCACCCAGAGCCACCGCTCCCACCTGTCTCAGGCTGCAAGCAACATAGCGGGGTGTTCAACCTCCAACC
CCACCACACCCCTGCCTAACCTGCCAGTGGGGCCTGGAGACACCATTTCCATTGCCAGTATCCAGAACTGGATTGCCAATGTAGTCAGTG
AGACCCTTGCTCAGAAGCAAAATGAAATGCTGCTGTTGTCCCGCTCACCGTCTGTTGCAAGCATGAAGGCAGTACCAGCGGCTAGCTGCC
TGGGGGATGACCAAGTCTCCATGCTTAGTGGACACAGCAGCTCCTCCTTGGGTGGCTGCCTGTTGCCTCAGAGCCAGGCAAGACCCAGCT
CTGACATGCAGTCTGTGCTGTCCTGCAACACCACACTGAGCTCACCCGCGGAAAGTTGCAGAAGCAAAGTGAGGGGGACCAGCAAGCCCA
TCTTCAGCCTCTTTGCTGACAATGTGGACCTAAAGGAACTTGGCCGGAAGGAGAAGGAGATGCAGATGGAGCTTAGGGAGAAGATGTCTG
AGTACAAAATGGAAAAGCTGGCCTCAGACAACAAACGCAGCTCCCTCTTCAAGAAGAAGAAGGTCAAGGAAGATGAGGATGATGGTGTGG
GTGATGGGGATGAGGACACTGACAGTGCCATAGGGAGCTTCCGATATTCTTCCCGCAGTAATTCCCAGAAACCTGAAACAGACACATGCT
CCTCCCTGGCTGTCTGTGATCACTATGCAAGTGGCAGCAGAGTTGGCAAAGAGATGGATAGCAGTATTAATAAGTGGCTCAGTGGCCTCA
GGACGGAGGAAAAACCTCCTTTCCAAAGTGACTGGTCTGGAAGTTCCAGAGGGAAGTACACCAGATCGTCCCTGCTCAGGGAGACAGAGT
CTAAATCCTCCAGTTACAAGTTTTCCAAATCCCAGTCAGAGGAACAGGACACCTCCTCCTACCACGAGGCAAATGGCAACTCTGTAAGAA
GCACTTCACGGTTCTCATCTTCCTCCACCAGGGAGGGCAGAGAGATGCACAAGTTCTCCAGGTCCACGTACAACGAGACCTCAAGTTCCC
GAGAGGAGAGCCCAGAGCCCTACTTCTTCCGCCGGACCCCAGAGTCCTCAGAAAGGGAAGAGTCCCCAGAACCACAGCGCCCAAATTGGG
CCAGGTCCAGGGACTGGGAAGATGTGGAAGAGTCATCCAAGTCAGACTTCTCTGAATTTGGAGCCAAGAGGAAGTTCACCCAGAGCTTTA
TGAGGTCTGAAGAAGAGGGAGAGAAAGAGAGGACAGAAAACAGAGAAGAAGGGAGGTTTGCATCTGGACGGCGGTCCCAGTATCGGAGAA
GCACTGACAGGGAGGAAGAGGAAGAAATGGACGATGAAGCCATCATTGCTGCTTGGAGACGCCGGCAAGAAGAAACCAGGACCAAGCTGC
AGAAAAGGAGGGAGGACTGAGCTGGGGAAAATCTGAGAACACTGAAAGAAACCACTCACGTTAGCATAGGGCTCAGGGCACACGTTGCCA
CCACTCATCGCAGGATGAGGATACAGAGAGGATCTTCCAGAGGGGCAGAGCCAAAATGAGAGGTACCAAGCATAAGGGCAGCAGAGGTGG
AGTAGGGAGGAGGCAAGGAGGGGGAGAACCATCAATACGAATACGAGGTCCGAATGCGGACCAACTGATACCATTTTCTGTTGCTCAGCG
CCCTCTAAGCTTTGGTGTTTCACTTAATGTATTTGGCAGTGTTCATCACAGGCTAGAGAGGTGAGCTTGGAAAAGCACTGTAGTTTGTCA
GAGACTCCAGTTTACATCCAGAAAGGCCATGAACATAGGACACGCTTCTGTCTGTAGAGGCTTCATATGAGACCCAGAAAGTCTATCCTA
TGGCAAGTCTGACCTCTCCTGGCAATGCTCAGTTCTGATTTTTTTTTTTTTAATGTTTTGAGTCTCCATTAAAAATGGTATGTTGGCAAA

>In-frame_ENST00000540905_ENST00000443333_TCGA-OL-A5D8-01A_KIFAP3_chr1_169993559_-_DUSP27_chr1_167095024_length(amino acids)=937AA_start in transcript=266_stop in transcript=3079
MVSSEMGISRSAVLVVAYLMIFHNMAILEALMTVRKKRAIYPNEGFLKQLRELNEKLMEEREEDYGREGGSAEAEEGEGTGSMLGARVHA
LTVEEEDDSASHLSGSSLGKATQASKPLTLIDEEEEEKLYEQWKKGQGLLSDKVPQDGGGWRSASSGQGGEELEDEDVERIIQEWQSRNE
RYQAEGYRRWGREEEKEEESDAGSSVGRRRRTLSESSAWESVSSHDIWVLKQQLELNRPDHGRRRRADSMSSESTWDAWNERLLEIEKEA
SRRYHAKSKREEAADRSSEAGSRVREDDEDSVGSEASSFYNFCSRNKDKLTALERWKIKRIQFGFHKKDLGAGDSSGEPGAEEAVGEKNP
SDVSLTAYQAWKLKHQKKVGSENKEEVVELSKGEDSALAKKRQRRLELLERSRQTLEESQSMASWEADSSTASGSIPLSAFWSADPSVSA
DGDTTSVLSTQSHRSHLSQAASNIAGCSTSNPTTPLPNLPVGPGDTISIASIQNWIANVVSETLAQKQNEMLLLSRSPSVASMKAVPAAS
CLGDDQVSMLSGHSSSSLGGCLLPQSQARPSSDMQSVLSCNTTLSSPAESCRSKVRGTSKPIFSLFADNVDLKELGRKEKEMQMELREKM
SEYKMEKLASDNKRSSLFKKKKVKEDEDDGVGDGDEDTDSAIGSFRYSSRSNSQKPETDTCSSLAVCDHYASGSRVGKEMDSSINKWLSG
LRTEEKPPFQSDWSGSSRGKYTRSSLLRETESKSSSYKFSKSQSEEQDTSSYHEANGNSVRSTSRFSSSSTREGREMHKFSRSTYNETSS
SREESPEPYFFRRTPESSEREESPEPQRPNWARSRDWEDVEESSKSDFSEFGAKRKFTQSFMRSEEEGEKERTENREEGRFASGRRSQYR

--------------------------------------------------------------

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Fusion Gene PPI Analysis for KIFAP3-DUSP27


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for KIFAP3-DUSP27


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for KIFAP3-DUSP27


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource