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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Fusion gene:KMT2A-AFF3 (FusionGDB2 ID:42941)

Fusion Gene Summary for KMT2A-AFF3

check button Fusion gene summary
Fusion gene informationFusion gene name: KMT2A-AFF3
Fusion gene ID: 42941
HgeneTgene
Gene symbol

KMT2A

AFF3

Gene ID

4297

3899

Gene namelysine methyltransferase 2AAF4/FMR2 family member 3
SynonymsALL-1|CXXC7|HRX|HTRX1|MLL|MLL1|MLL1A|TRX1|WDSTSLAF4|MLLT2-like
Cytomap

11q23.3

2q11.2

Type of geneprotein-codingprotein-coding
Descriptionhistone-lysine N-methyltransferase 2ACXXC-type zinc finger protein 7lysine (K)-specific methyltransferase 2Alysine N-methyltransferase 2Amixed lineage leukemia 1myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)trithorax-likeAF4/FMR2 family member 3MLLT2-related proteinlymphoid nuclear protein 4lymphoid nuclear protein related to AF4protein LAF-4
Modification date2020031920200313
UniProtAcc

Q03164

P51826

Ensembl transtripts involved in fusion geneENST00000534358, ENST00000389506, 
ENST00000354520, ENST00000420751, 
ENST00000409236, ENST00000356421, 
ENST00000317233, ENST00000409579, 
ENST00000483600, 
Fusion gene scores* DoF score79 X 196 X 13=20129214 X 19 X 6=1596
# samples 24116
** MAII scorelog2(241/201292*10)=-6.38411287931608
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(16/1596*10)=-3.31831684133498
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: KMT2A [Title/Abstract] AND AFF3 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointKMT2A(118353211)-AFF3(100368765), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneKMT2A

GO:0044648

histone H3-K4 dimethylation

25561738

HgeneKMT2A

GO:0045944

positive regulation of transcription by RNA polymerase II

20861184

HgeneKMT2A

GO:0051568

histone H3-K4 methylation

19556245

HgeneKMT2A

GO:0065003

protein-containing complex assembly

15199122

HgeneKMT2A

GO:0080182

histone H3-K4 trimethylation

20861184

HgeneKMT2A

GO:0097692

histone H3-K4 monomethylation

25561738|26324722


check buttonFusion gene breakpoints across KMT2A (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across AFF3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChiTaRS5.0N/AAF422798KMT2Achr11

118353211

+AFF3chr2

100368765

-


Top

Fusion Gene ORF analysis for KMT2A-AFF3

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000534358ENST00000409236KMT2Achr11

118353211

+AFF3chr2

100368765

-
In-frameENST00000534358ENST00000356421KMT2Achr11

118353211

+AFF3chr2

100368765

-
In-frameENST00000534358ENST00000317233KMT2Achr11

118353211

+AFF3chr2

100368765

-
In-frameENST00000534358ENST00000409579KMT2Achr11

118353211

+AFF3chr2

100368765

-
5CDS-intronENST00000534358ENST00000483600KMT2Achr11

118353211

+AFF3chr2

100368765

-
In-frameENST00000389506ENST00000409236KMT2Achr11

118353211

+AFF3chr2

100368765

-
In-frameENST00000389506ENST00000356421KMT2Achr11

118353211

+AFF3chr2

100368765

-
In-frameENST00000389506ENST00000317233KMT2Achr11

118353211

+AFF3chr2

100368765

-
In-frameENST00000389506ENST00000409579KMT2Achr11

118353211

+AFF3chr2

100368765

-
5CDS-intronENST00000389506ENST00000483600KMT2Achr11

118353211

+AFF3chr2

100368765

-
In-frameENST00000354520ENST00000409236KMT2Achr11

118353211

+AFF3chr2

100368765

-
In-frameENST00000354520ENST00000356421KMT2Achr11

118353211

+AFF3chr2

100368765

-
In-frameENST00000354520ENST00000317233KMT2Achr11

118353211

+AFF3chr2

100368765

-
In-frameENST00000354520ENST00000409579KMT2Achr11

118353211

+AFF3chr2

100368765

-
5CDS-intronENST00000354520ENST00000483600KMT2Achr11

118353211

+AFF3chr2

100368765

-
intron-3CDSENST00000420751ENST00000409236KMT2Achr11

118353211

+AFF3chr2

100368765

-
intron-3CDSENST00000420751ENST00000356421KMT2Achr11

118353211

+AFF3chr2

100368765

-
intron-3CDSENST00000420751ENST00000317233KMT2Achr11

118353211

+AFF3chr2

100368765

-
intron-3CDSENST00000420751ENST00000409579KMT2Achr11

118353211

+AFF3chr2

100368765

-
intron-intronENST00000420751ENST00000483600KMT2Achr11

118353211

+AFF3chr2

100368765

-
3UTR-3CDSENST00000420751ENST00000317233KMT2Achr11

118352807

+AFF3chr2

100343590

-
3UTR-3CDSENST00000420751ENST00000317233KMT2Achr11

118355029

+AFF3chr2

100360602

-
3UTR-3CDSENST00000420751ENST00000356421KMT2Achr11

118352807

+AFF3chr2

100343590

-
3UTR-3CDSENST00000420751ENST00000356421KMT2Achr11

118355029

+AFF3chr2

100360602

-
3UTR-3CDSENST00000420751ENST00000409236KMT2Achr11

118352807

+AFF3chr2

100343590

-
3UTR-3CDSENST00000420751ENST00000409236KMT2Achr11

118355029

+AFF3chr2

100360602

-
3UTR-3CDSENST00000420751ENST00000409579KMT2Achr11

118352807

+AFF3chr2

100343590

-
3UTR-3CDSENST00000420751ENST00000409579KMT2Achr11

118355029

+AFF3chr2

100360602

-
3UTR-intronENST00000420751ENST00000483600KMT2Achr11

118352807

+AFF3chr2

100343590

-
3UTR-intronENST00000420751ENST00000483600KMT2Achr11

118355029

+AFF3chr2

100360602

-
5CDS-intronENST00000354520ENST00000483600KMT2Achr11

118352807

+AFF3chr2

100343590

-
5CDS-intronENST00000354520ENST00000483600KMT2Achr11

118353210

+AFF3chr2

100360602

-
5CDS-intronENST00000354520ENST00000483600KMT2Achr11

118353210

+AFF3chr2

100623479

-
5CDS-intronENST00000354520ENST00000483600KMT2Achr11

118355029

+AFF3chr2

100360602

-
5CDS-intronENST00000354520ENST00000483600KMT2Achr11

118353210

+AFF3chr2

100360602

5CDS-intronENST00000389506ENST00000483600KMT2Achr11

118352807

+AFF3chr2

100343590

-
5CDS-intronENST00000389506ENST00000483600KMT2Achr11

118353210

+AFF3chr2

100360602

-
5CDS-intronENST00000389506ENST00000483600KMT2Achr11

118353210

+AFF3chr2

100623479

-
5CDS-intronENST00000389506ENST00000483600KMT2Achr11

118355029

+AFF3chr2

100360602

-
5CDS-intronENST00000389506ENST00000483600KMT2Achr11

118353210

+AFF3chr2

100360602

5CDS-intronENST00000534358ENST00000483600KMT2Achr11

118352807

+AFF3chr2

100343590

-
5CDS-intronENST00000534358ENST00000483600KMT2Achr11

118353210

+AFF3chr2

100360602

-
5CDS-intronENST00000534358ENST00000483600KMT2Achr11

118353210

+AFF3chr2

100623479

-
5CDS-intronENST00000534358ENST00000483600KMT2Achr11

118355029

+AFF3chr2

100360602

-
5CDS-intronENST00000534358ENST00000483600KMT2Achr11

118353210

+AFF3chr2

100360602

Frame-shiftENST00000354520ENST00000317233KMT2Achr11

118353210

+AFF3chr2

100623479

-
Frame-shiftENST00000354520ENST00000356421KMT2Achr11

118353210

+AFF3chr2

100623479

-
Frame-shiftENST00000354520ENST00000409236KMT2Achr11

118353210

+AFF3chr2

100623479

-
Frame-shiftENST00000354520ENST00000409579KMT2Achr11

118353210

+AFF3chr2

100623479

-
Frame-shiftENST00000389506ENST00000317233KMT2Achr11

118353210

+AFF3chr2

100623479

-
Frame-shiftENST00000389506ENST00000356421KMT2Achr11

118353210

+AFF3chr2

100623479

-
Frame-shiftENST00000389506ENST00000409236KMT2Achr11

118353210

+AFF3chr2

100623479

-
Frame-shiftENST00000389506ENST00000409579KMT2Achr11

118353210

+AFF3chr2

100623479

-
Frame-shiftENST00000534358ENST00000317233KMT2Achr11

118353210

+AFF3chr2

100623479

-
Frame-shiftENST00000534358ENST00000356421KMT2Achr11

118353210

+AFF3chr2

100623479

-
Frame-shiftENST00000534358ENST00000409236KMT2Achr11

118353210

+AFF3chr2

100623479

-
Frame-shiftENST00000534358ENST00000409579KMT2Achr11

118353210

+AFF3chr2

100623479

-
In-frameENST00000354520ENST00000317233KMT2Achr11

118352807

+AFF3chr2

100343590

-
In-frameENST00000354520ENST00000317233KMT2Achr11

118353210

+AFF3chr2

100360602

-
In-frameENST00000354520ENST00000317233KMT2Achr11

118355029

+AFF3chr2

100360602

-
In-frameENST00000354520ENST00000317233KMT2Achr11

118353210

+AFF3chr2

100360602

In-frameENST00000354520ENST00000356421KMT2Achr11

118352807

+AFF3chr2

100343590

-
In-frameENST00000354520ENST00000356421KMT2Achr11

118353210

+AFF3chr2

100360602

-
In-frameENST00000354520ENST00000356421KMT2Achr11

118355029

+AFF3chr2

100360602

-
In-frameENST00000354520ENST00000356421KMT2Achr11

118353210

+AFF3chr2

100360602

In-frameENST00000354520ENST00000409236KMT2Achr11

118352807

+AFF3chr2

100343590

-
In-frameENST00000354520ENST00000409236KMT2Achr11

118353210

+AFF3chr2

100360602

-
In-frameENST00000354520ENST00000409236KMT2Achr11

118355029

+AFF3chr2

100360602

-
In-frameENST00000354520ENST00000409236KMT2Achr11

118353210

+AFF3chr2

100360602

In-frameENST00000354520ENST00000409579KMT2Achr11

118352807

+AFF3chr2

100343590

-
In-frameENST00000354520ENST00000409579KMT2Achr11

118353210

+AFF3chr2

100360602

-
In-frameENST00000354520ENST00000409579KMT2Achr11

118355029

+AFF3chr2

100360602

-
In-frameENST00000354520ENST00000409579KMT2Achr11

118353210

+AFF3chr2

100360602

In-frameENST00000389506ENST00000317233KMT2Achr11

118352807

+AFF3chr2

100343590

-
In-frameENST00000389506ENST00000317233KMT2Achr11

118353210

+AFF3chr2

100360602

-
In-frameENST00000389506ENST00000317233KMT2Achr11

118355029

+AFF3chr2

100360602

-
In-frameENST00000389506ENST00000317233KMT2Achr11

118353210

+AFF3chr2

100360602

In-frameENST00000389506ENST00000356421KMT2Achr11

118352807

+AFF3chr2

100343590

-
In-frameENST00000389506ENST00000356421KMT2Achr11

118353210

+AFF3chr2

100360602

-
In-frameENST00000389506ENST00000356421KMT2Achr11

118355029

+AFF3chr2

100360602

-
In-frameENST00000389506ENST00000356421KMT2Achr11

118353210

+AFF3chr2

100360602

In-frameENST00000389506ENST00000409236KMT2Achr11

118352807

+AFF3chr2

100343590

-
In-frameENST00000389506ENST00000409236KMT2Achr11

118353210

+AFF3chr2

100360602

-
In-frameENST00000389506ENST00000409236KMT2Achr11

118355029

+AFF3chr2

100360602

-
In-frameENST00000389506ENST00000409236KMT2Achr11

118353210

+AFF3chr2

100360602

In-frameENST00000389506ENST00000409579KMT2Achr11

118352807

+AFF3chr2

100343590

-
In-frameENST00000389506ENST00000409579KMT2Achr11

118353210

+AFF3chr2

100360602

-
In-frameENST00000389506ENST00000409579KMT2Achr11

118355029

+AFF3chr2

100360602

-
In-frameENST00000389506ENST00000409579KMT2Achr11

118353210

+AFF3chr2

100360602

In-frameENST00000534358ENST00000317233KMT2Achr11

118352807

+AFF3chr2

100343590

-
In-frameENST00000534358ENST00000317233KMT2Achr11

118353210

+AFF3chr2

100360602

-
In-frameENST00000534358ENST00000317233KMT2Achr11

118355029

+AFF3chr2

100360602

-
In-frameENST00000534358ENST00000317233KMT2Achr11

118353210

+AFF3chr2

100360602

In-frameENST00000534358ENST00000356421KMT2Achr11

118352807

+AFF3chr2

100343590

-
In-frameENST00000534358ENST00000356421KMT2Achr11

118353210

+AFF3chr2

100360602

-
In-frameENST00000534358ENST00000356421KMT2Achr11

118355029

+AFF3chr2

100360602

-
In-frameENST00000534358ENST00000356421KMT2Achr11

118353210

+AFF3chr2

100360602

In-frameENST00000534358ENST00000409236KMT2Achr11

118352807

+AFF3chr2

100343590

-
In-frameENST00000534358ENST00000409236KMT2Achr11

118353210

+AFF3chr2

100360602

-
In-frameENST00000534358ENST00000409236KMT2Achr11

118355029

+AFF3chr2

100360602

-
In-frameENST00000534358ENST00000409236KMT2Achr11

118353210

+AFF3chr2

100360602

In-frameENST00000534358ENST00000409579KMT2Achr11

118352807

+AFF3chr2

100343590

-
In-frameENST00000534358ENST00000409579KMT2Achr11

118353210

+AFF3chr2

100360602

-
In-frameENST00000534358ENST00000409579KMT2Achr11

118355029

+AFF3chr2

100360602

-
In-frameENST00000534358ENST00000409579KMT2Achr11

118353210

+AFF3chr2

100360602

intron-3CDSENST00000420751ENST00000317233KMT2Achr11

118353210

+AFF3chr2

100360602

-
intron-3CDSENST00000420751ENST00000317233KMT2Achr11

118353210

+AFF3chr2

100623479

-
intron-3CDSENST00000420751ENST00000317233KMT2Achr11

118353210

+AFF3chr2

100360602

intron-3CDSENST00000420751ENST00000356421KMT2Achr11

118353210

+AFF3chr2

100360602

-
intron-3CDSENST00000420751ENST00000356421KMT2Achr11

118353210

+AFF3chr2

100623479

-
intron-3CDSENST00000420751ENST00000356421KMT2Achr11

118353210

+AFF3chr2

100360602

intron-3CDSENST00000420751ENST00000409236KMT2Achr11

118353210

+AFF3chr2

100360602

-
intron-3CDSENST00000420751ENST00000409236KMT2Achr11

118353210

+AFF3chr2

100623479

-
intron-3CDSENST00000420751ENST00000409236KMT2Achr11

118353210

+AFF3chr2

100360602

intron-3CDSENST00000420751ENST00000409579KMT2Achr11

118353210

+AFF3chr2

100360602

-
intron-3CDSENST00000420751ENST00000409579KMT2Achr11

118353210

+AFF3chr2

100623479

-
intron-3CDSENST00000420751ENST00000409579KMT2Achr11

118353210

+AFF3chr2

100360602

intron-intronENST00000420751ENST00000483600KMT2Achr11

118353210

+AFF3chr2

100360602

-
intron-intronENST00000420751ENST00000483600KMT2Achr11

118353210

+AFF3chr2

100623479

-
intron-intronENST00000420751ENST00000483600KMT2Achr11

118353210

+AFF3chr2

100360602


check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000534358KMT2Achr11118353211+ENST00000409236AFF3chr2100368765-1248241092368682281
ENST00000534358KMT2Achr11118353211+ENST00000356421AFF3chr2100368765-1108741092368682281
ENST00000534358KMT2Achr11118353211+ENST00000317233AFF3chr2100368765-1108741092368682281
ENST00000534358KMT2Achr11118353211+ENST00000409579AFF3chr2100368765-722241092368682281
ENST00000389506KMT2Achr11118353211+ENST00000409236AFF3chr2100368765-124594086068452281
ENST00000389506KMT2Achr11118353211+ENST00000356421AFF3chr2100368765-110644086068452281
ENST00000389506KMT2Achr11118353211+ENST00000317233AFF3chr2100368765-110644086068452281
ENST00000389506KMT2Achr11118353211+ENST00000409579AFF3chr2100368765-71994086068452281
ENST00000354520KMT2Achr11118353211+ENST00000409236AFF3chr2100368765-124594086068452281
ENST00000354520KMT2Achr11118353211+ENST00000356421AFF3chr2100368765-110644086068452281
ENST00000354520KMT2Achr11118353211+ENST00000317233AFF3chr2100368765-110644086068452281
ENST00000354520KMT2Achr11118353211+ENST00000409579AFF3chr2100368765-71994086068452281

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000534358ENST00000409236KMT2Achr11118353211+AFF3chr2100368765-0.0004268980.99957305
ENST00000534358ENST00000356421KMT2Achr11118353211+AFF3chr2100368765-0.0005108640.99948907
ENST00000534358ENST00000317233KMT2Achr11118353211+AFF3chr2100368765-0.0005108640.99948907
ENST00000534358ENST00000409579KMT2Achr11118353211+AFF3chr2100368765-0.0014970490.99850297
ENST00000389506ENST00000409236KMT2Achr11118353211+AFF3chr2100368765-0.000414260.9995857
ENST00000389506ENST00000356421KMT2Achr11118353211+AFF3chr2100368765-0.0004956180.9995043
ENST00000389506ENST00000317233KMT2Achr11118353211+AFF3chr2100368765-0.0004956180.9995043
ENST00000389506ENST00000409579KMT2Achr11118353211+AFF3chr2100368765-0.0014633770.9985366
ENST00000354520ENST00000409236KMT2Achr11118353211+AFF3chr2100368765-0.000414260.9995857
ENST00000354520ENST00000356421KMT2Achr11118353211+AFF3chr2100368765-0.0004956180.9995043
ENST00000354520ENST00000317233KMT2Achr11118353211+AFF3chr2100368765-0.0004956180.9995043
ENST00000354520ENST00000409579KMT2Achr11118353211+AFF3chr2100368765-0.0014633770.9985366

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Fusion Genomic Features for KMT2A-AFF3


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for KMT2A-AFF3


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FGviewer for the breakpoints of chr11:118353211-chr2:100368765

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- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
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check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
KMT2A

Q03164

AFF3

P51826

FUNCTION: Histone methyltransferase that plays an essential role in early development and hematopoiesis (PubMed:15960975, PubMed:12453419, PubMed:15960975, PubMed:19556245, PubMed:19187761, PubMed:20677832, PubMed:21220120, PubMed:26886794). Catalytic subunit of the MLL1/MLL complex, a multiprotein complex that mediates both methylation of 'Lys-4' of histone H3 (H3K4me) complex and acetylation of 'Lys-16' of histone H4 (H4K16ac) (PubMed:15960975, PubMed:12453419, PubMed:15960975, PubMed:19556245, PubMed:24235145, PubMed:19187761, PubMed:20677832, PubMed:21220120, PubMed:26886794). Catalyzes methyl group transfer from S-adenosyl-L-methionine to the epsilon-amino group of 'Lys-4' of histone H3 (H3K4) via a non-processive mechanism. Part of chromatin remodeling machinery predominantly forms H3K4me1 and H3K4me2 methylation marks at active chromatin sites where transcription and DNA repair take place (PubMed:25561738, PubMed:15960975, PubMed:12453419, PubMed:15960975, PubMed:19556245, PubMed:19187761, PubMed:20677832, PubMed:21220120, PubMed:26886794). Has weak methyltransferase activity by itself, and requires other component of the MLL1/MLL complex to obtain full methyltransferase activity (PubMed:19187761, PubMed:26886794). Has no activity toward histone H3 phosphorylated on 'Thr-3', less activity toward H3 dimethylated on 'Arg-8' or 'Lys-9', while it has higher activity toward H3 acetylated on 'Lys-9' (PubMed:19187761). Binds to unmethylated CpG elements in the promoter of target genes and helps maintain them in the nonmethylated state (PubMed:20010842). Required for transcriptional activation of HOXA9 (PubMed:12453419, PubMed:20677832, PubMed:20010842). Promotes PPP1R15A-induced apoptosis (PubMed:10490642). Plays a critical role in the control of circadian gene expression and is essential for the transcriptional activation mediated by the CLOCK-ARNTL/BMAL1 heterodimer (By similarity). Establishes a permissive chromatin state for circadian transcription by mediating a rhythmic methylation of 'Lys-4' of histone H3 (H3K4me) and this histone modification directs the circadian acetylation at H3K9 and H3K14 allowing the recruitment of CLOCK-ARNTL/BMAL1 to chromatin (By similarity). Also has auto-methylation activity on Cys-3882 in absence of histone H3 substrate (PubMed:24235145). {ECO:0000250|UniProtKB:P55200, ECO:0000269|PubMed:10490642, ECO:0000269|PubMed:12453419, ECO:0000269|PubMed:15960975, ECO:0000269|PubMed:19187761, ECO:0000269|PubMed:19556245, ECO:0000269|PubMed:20010842, ECO:0000269|PubMed:21220120, ECO:0000269|PubMed:24235145, ECO:0000269|PubMed:26886794, ECO:0000305|PubMed:20677832}.FUNCTION: Putative transcription activator that may function in lymphoid development and oncogenesis. Binds, in vitro, to double-stranded DNA.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

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* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneKMT2Achr11:118353211chr2:100368765ENST00000354520+835137_1431362.03932.0Compositional biasNote=Poly-Gly
HgeneKMT2Achr11:118353211chr2:100368765ENST00000354520+83517_1021362.03932.0Compositional biasNote=Ala/Gly/Ser-rich
HgeneKMT2Achr11:118353211chr2:100368765ENST00000354520+835561_5641362.03932.0Compositional biasNote=Poly-Pro
HgeneKMT2Achr11:118353211chr2:100368765ENST00000354520+835568_5711362.03932.0Compositional biasNote=Poly-Pro
HgeneKMT2Achr11:118353211chr2:100368765ENST00000389506+836137_1431362.03970.0Compositional biasNote=Poly-Gly
HgeneKMT2Achr11:118353211chr2:100368765ENST00000389506+83617_1021362.03970.0Compositional biasNote=Ala/Gly/Ser-rich
HgeneKMT2Achr11:118353211chr2:100368765ENST00000389506+836561_5641362.03970.0Compositional biasNote=Poly-Pro
HgeneKMT2Achr11:118353211chr2:100368765ENST00000389506+836568_5711362.03970.0Compositional biasNote=Poly-Pro
HgeneKMT2Achr11:118353211chr2:100368765ENST00000534358+836137_1431362.03973.0Compositional biasNote=Poly-Gly
HgeneKMT2Achr11:118353211chr2:100368765ENST00000534358+83617_1021362.03973.0Compositional biasNote=Ala/Gly/Ser-rich
HgeneKMT2Achr11:118353211chr2:100368765ENST00000534358+836561_5641362.03973.0Compositional biasNote=Poly-Pro
HgeneKMT2Achr11:118353211chr2:100368765ENST00000534358+836568_5711362.03973.0Compositional biasNote=Poly-Pro
HgeneKMT2Achr11:118353211chr2:100368765ENST00000354520+835169_1801362.03932.0DNA bindingNote=A.T hook 1
HgeneKMT2Achr11:118353211chr2:100368765ENST00000354520+835217_2271362.03932.0DNA bindingNote=A.T hook 2
HgeneKMT2Achr11:118353211chr2:100368765ENST00000354520+835301_3091362.03932.0DNA bindingNote=A.T hook 3
HgeneKMT2Achr11:118353211chr2:100368765ENST00000389506+836169_1801362.03970.0DNA bindingNote=A.T hook 1
HgeneKMT2Achr11:118353211chr2:100368765ENST00000389506+836217_2271362.03970.0DNA bindingNote=A.T hook 2
HgeneKMT2Achr11:118353211chr2:100368765ENST00000389506+836301_3091362.03970.0DNA bindingNote=A.T hook 3
HgeneKMT2Achr11:118353211chr2:100368765ENST00000534358+836169_1801362.03973.0DNA bindingNote=A.T hook 1
HgeneKMT2Achr11:118353211chr2:100368765ENST00000534358+836217_2271362.03973.0DNA bindingNote=A.T hook 2
HgeneKMT2Achr11:118353211chr2:100368765ENST00000534358+836301_3091362.03973.0DNA bindingNote=A.T hook 3
HgeneKMT2Achr11:118353211chr2:100368765ENST00000354520+835123_1341362.03932.0MotifIntegrase domain-binding motif 1 (IBM1)
HgeneKMT2Achr11:118353211chr2:100368765ENST00000354520+835147_1521362.03932.0MotifIntegrase domain-binding motif 2 (IBM2)
HgeneKMT2Achr11:118353211chr2:100368765ENST00000354520+8356_251362.03932.0MotifMenin-binding motif (MBM)
HgeneKMT2Achr11:118353211chr2:100368765ENST00000389506+836123_1341362.03970.0MotifIntegrase domain-binding motif 1 (IBM1)
HgeneKMT2Achr11:118353211chr2:100368765ENST00000389506+836147_1521362.03970.0MotifIntegrase domain-binding motif 2 (IBM2)
HgeneKMT2Achr11:118353211chr2:100368765ENST00000389506+8366_251362.03970.0MotifMenin-binding motif (MBM)
HgeneKMT2Achr11:118353211chr2:100368765ENST00000534358+836123_1341362.03973.0MotifIntegrase domain-binding motif 1 (IBM1)
HgeneKMT2Achr11:118353211chr2:100368765ENST00000534358+836147_1521362.03973.0MotifIntegrase domain-binding motif 2 (IBM2)
HgeneKMT2Achr11:118353211chr2:100368765ENST00000534358+8366_251362.03973.0MotifMenin-binding motif (MBM)
HgeneKMT2Achr11:118353211chr2:100368765ENST00000354520+8351147_11951362.03932.0Zinc fingerCXXC-type
HgeneKMT2Achr11:118353211chr2:100368765ENST00000389506+8361147_11951362.03970.0Zinc fingerCXXC-type
HgeneKMT2Achr11:118353211chr2:100368765ENST00000534358+8361147_11951362.03973.0Zinc fingerCXXC-type
TgeneAFF3chr11:118353211chr2:100368765ENST00000317233624413_419307.01227.0Compositional biasNote=Poly-Ser
TgeneAFF3chr11:118353211chr2:100368765ENST00000317233624422_432307.01227.0Compositional biasNote=Poly-Ser
TgeneAFF3chr11:118353211chr2:100368765ENST00000317233624440_445307.01227.0Compositional biasNote=Poly-Ser
TgeneAFF3chr11:118353211chr2:100368765ENST00000317233624670_679307.01227.0Compositional biasNote=Poly-Ser
TgeneAFF3chr11:118353211chr2:100368765ENST00000356421624413_419332.01252.0Compositional biasNote=Poly-Ser
TgeneAFF3chr11:118353211chr2:100368765ENST00000356421624422_432332.01252.0Compositional biasNote=Poly-Ser
TgeneAFF3chr11:118353211chr2:100368765ENST00000356421624440_445332.01252.0Compositional biasNote=Poly-Ser
TgeneAFF3chr11:118353211chr2:100368765ENST00000356421624670_679332.01252.0Compositional biasNote=Poly-Ser
TgeneAFF3chr11:118353211chr2:100368765ENST00000409236523413_419307.01227.0Compositional biasNote=Poly-Ser
TgeneAFF3chr11:118353211chr2:100368765ENST00000409236523422_432307.01227.0Compositional biasNote=Poly-Ser
TgeneAFF3chr11:118353211chr2:100368765ENST00000409236523440_445307.01227.0Compositional biasNote=Poly-Ser
TgeneAFF3chr11:118353211chr2:100368765ENST00000409236523670_679307.01227.0Compositional biasNote=Poly-Ser
TgeneAFF3chr11:118353211chr2:100368765ENST00000409579725413_419332.01252.0Compositional biasNote=Poly-Ser
TgeneAFF3chr11:118353211chr2:100368765ENST00000409579725422_432332.01252.0Compositional biasNote=Poly-Ser
TgeneAFF3chr11:118353211chr2:100368765ENST00000409579725440_445332.01252.0Compositional biasNote=Poly-Ser
TgeneAFF3chr11:118353211chr2:100368765ENST00000409579725670_679332.01252.0Compositional biasNote=Poly-Ser

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneKMT2Achr11:118353211chr2:100368765ENST00000354520+8351703_17481362.03932.0DomainBromo%3B divergent
HgeneKMT2Achr11:118353211chr2:100368765ENST00000354520+8352018_20741362.03932.0DomainFYR N-terminal
HgeneKMT2Achr11:118353211chr2:100368765ENST00000354520+8353666_37471362.03932.0DomainFYR C-terminal
HgeneKMT2Achr11:118353211chr2:100368765ENST00000354520+8353829_39451362.03932.0DomainSET
HgeneKMT2Achr11:118353211chr2:100368765ENST00000354520+8353953_39691362.03932.0DomainPost-SET
HgeneKMT2Achr11:118353211chr2:100368765ENST00000389506+8361703_17481362.03970.0DomainBromo%3B divergent
HgeneKMT2Achr11:118353211chr2:100368765ENST00000389506+8362018_20741362.03970.0DomainFYR N-terminal
HgeneKMT2Achr11:118353211chr2:100368765ENST00000389506+8363666_37471362.03970.0DomainFYR C-terminal
HgeneKMT2Achr11:118353211chr2:100368765ENST00000389506+8363829_39451362.03970.0DomainSET
HgeneKMT2Achr11:118353211chr2:100368765ENST00000389506+8363953_39691362.03970.0DomainPost-SET
HgeneKMT2Achr11:118353211chr2:100368765ENST00000534358+8361703_17481362.03973.0DomainBromo%3B divergent
HgeneKMT2Achr11:118353211chr2:100368765ENST00000534358+8362018_20741362.03973.0DomainFYR N-terminal
HgeneKMT2Achr11:118353211chr2:100368765ENST00000534358+8363666_37471362.03973.0DomainFYR C-terminal
HgeneKMT2Achr11:118353211chr2:100368765ENST00000534358+8363829_39451362.03973.0DomainSET
HgeneKMT2Achr11:118353211chr2:100368765ENST00000534358+8363953_39691362.03973.0DomainPost-SET
HgeneKMT2Achr11:118353211chr2:100368765ENST00000354520+8353906_39071362.03932.0RegionS-adenosyl-L-methionine binding
HgeneKMT2Achr11:118353211chr2:100368765ENST00000389506+8363906_39071362.03970.0RegionS-adenosyl-L-methionine binding
HgeneKMT2Achr11:118353211chr2:100368765ENST00000534358+8363906_39071362.03973.0RegionS-adenosyl-L-methionine binding
HgeneKMT2Achr11:118353211chr2:100368765ENST00000354520+8351431_14821362.03932.0Zinc fingerPHD-type 1
HgeneKMT2Achr11:118353211chr2:100368765ENST00000354520+8351479_15331362.03932.0Zinc fingerPHD-type 2
HgeneKMT2Achr11:118353211chr2:100368765ENST00000354520+8351566_16271362.03932.0Zinc fingerPHD-type 3
HgeneKMT2Achr11:118353211chr2:100368765ENST00000354520+8351870_19101362.03932.0Zinc fingerC2HC pre-PHD-type
HgeneKMT2Achr11:118353211chr2:100368765ENST00000354520+8351931_19781362.03932.0Zinc fingerPHD-type 4
HgeneKMT2Achr11:118353211chr2:100368765ENST00000389506+8361431_14821362.03970.0Zinc fingerPHD-type 1
HgeneKMT2Achr11:118353211chr2:100368765ENST00000389506+8361479_15331362.03970.0Zinc fingerPHD-type 2
HgeneKMT2Achr11:118353211chr2:100368765ENST00000389506+8361566_16271362.03970.0Zinc fingerPHD-type 3
HgeneKMT2Achr11:118353211chr2:100368765ENST00000389506+8361870_19101362.03970.0Zinc fingerC2HC pre-PHD-type
HgeneKMT2Achr11:118353211chr2:100368765ENST00000389506+8361931_19781362.03970.0Zinc fingerPHD-type 4
HgeneKMT2Achr11:118353211chr2:100368765ENST00000534358+8361431_14821362.03973.0Zinc fingerPHD-type 1
HgeneKMT2Achr11:118353211chr2:100368765ENST00000534358+8361479_15331362.03973.0Zinc fingerPHD-type 2
HgeneKMT2Achr11:118353211chr2:100368765ENST00000534358+8361566_16271362.03973.0Zinc fingerPHD-type 3
HgeneKMT2Achr11:118353211chr2:100368765ENST00000534358+8361870_19101362.03973.0Zinc fingerC2HC pre-PHD-type
HgeneKMT2Achr11:118353211chr2:100368765ENST00000534358+8361931_19781362.03973.0Zinc fingerPHD-type 4


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Fusion Gene Sequence for KMT2A-AFF3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000534358_ENST00000409236_AF422798_KMT2A_chr11_118353211_+_AFF3_chr2_100368765_length(transcript)=12482nt_BP=4109nt
CTGCTTCACTTCACGGGGCGAACATGGCGCACAGCTGTCGGTGGCGCTTCCCCGCCCGACCCGGGACCACCGGGGGCGGCGGCGGCGGGG
GGCGCCGGGGCCTAGGGGGCGCCCCGCGGCAACGCGTCCCGGCCCTGCTGCTTCCCCCCGGGCCCCCGGTCGGCGGTGGCGGCCCCGGGG
CGCCCCCCTCCCCCCCGGCTGTGGCGGCCGCGGCGGCGGCGGCGGGAAGCAGCGGGGCTGGGGTTCCAGGGGGAGCGGCCGCCGCCTCAG
CAGCCTCCTCGTCGTCCGCCTCGTCTTCGTCTTCGTCATCGTCCTCAGCCTCTTCAGGGCCGGCCCTGCTCCGGGTGGGCCCGGGCTTCG
ACGCGGCGCTGCAGGTCTCGGCCGCCATCGGCACCAACCTGCGCCGGTTCCGGGCCGTGTTTGGGGAGAGCGGCGGGGGAGGCGGCAGCG
GAGAGGATGAGCAATTCTTAGGTTTTGGCTCAGATGAAGAAGTCAGAGTGCGAAGTCCCACAAGGTCTCCTTCAGTTAAAACTAGTCCTC
GAAAACCTCGTGGGAGACCTAGAAGTGGCTCTGACCGAAATTCAGCTATCCTCTCAGATCCATCTGTGTTTTCCCCTCTAAATAAATCAG
AGACCAAATCTGGAGATAAGATCAAGAAGAAAGATTCTAAAAGTATAGAAAAGAAGAGAGGAAGACCTCCCACCTTCCCTGGAGTAAAAA
TCAAAATAACACATGGAAAGGACATTTCAGAGTTACCAAAGGGAAACAAAGAAGATAGCCTGAAAAAAATTAAAAGGACACCTTCTGCTA
CGTTTCAGCAAGCCACAAAGATTAAAAAATTAAGAGCAGGTAAACTCTCTCCTCTCAAGTCTAAGTTTAAGACAGGGAAGCTTCAAATAG
GAAGGAAGGGGGTACAAATTGTACGACGGAGAGGAAGGCCTCCATCAACAGAAAGGATAAAGACCCCTTCGGGTCTCCTCATTAATTCTG
AACTGGAAAAGCCCCAGAAAGTCCGGAAAGACAAGGAAGGAACACCTCCACTTACAAAAGAAGATAAGACAGTTGTCAGACAAAGCCCTC
GAAGGATTAAGCCAGTTAGGATTATTCCTTCTTCAAAAAGGACAGATGCAACCATTGCTAAGCAACTCTTACAGAGGGCAAAAAAGGGGG
CTCAAAAGAAAATTGAAAAAGAAGCAGCTCAGCTGCAGGGAAGAAAGGTGAAGACACAGGTCAAAAATATTCGACAGTTCATCATGCCTG
TTGTCAGTGCTATCTCCTCGCGGATCATTAAGACCCCTCGGCGGTTTATAGAGGATGAGGATTATGACCCTCCAATTAAAATTGCCCGAT
TAGAGTCTACACCGAATAGTAGATTCAGTGCCCCGTCCTGTGGATCTTCTGAAAAATCAAGTGCAGCTTCTCAGCACTCCTCTCAAATGT
CTTCAGACTCCTCTCGATCTAGTAGCCCCAGTGTTGATACCTCCACAGACTCTCAGGCTTCTGAGGAGATTCAGGTACTTCCTGAGGAGC
GGAGCGATACCCCTGAAGTTCATCCTCCACTGCCCATTTCCCAGTCCCCAGAAAATGAGAGTAATGATAGGAGAAGCAGAAGGTATTCAG
TGTCGGAGAGAAGTTTTGGATCTAGAACGACGAAAAAATTATCAACTCTACAAAGTGCCCCCCAGCAGCAGACCTCCTCGTCTCCACCTC
CACCTCTGCTGACTCCACCGCCACCACTGCAGCCAGCCTCCAGTATCTCTGACCACACACCTTGGCTTATGCCTCCAACAATCCCCTTAG
CATCACCATTTTTGCCTGCTTCCACTGCTCCTATGCAAGGGAAGCGAAAATCTATTTTGCGAGAACCGACATTTAGGTGGACTTCTTTAA
AGCATTCTAGGTCAGAGCCACAATACTTTTCCTCAGCAAAGTATGCCAAAGAAGGTCTTATTCGCAAACCAATATTTGATAATTTCCGAC
CCCCTCCACTAACTCCCGAGGACGTTGGCTTTGCATCTGGTTTTTCTGCATCTGGTACCGCTGCTTCAGCCCGATTGTTTTCGCCACTCC
ATTCTGGAACAAGGTTTGATATGCACAAAAGGAGCCCTCTTCTGAGAGCTCCAAGATTTACTCCAAGTGAGGCTCACTCTAGAATATTTG
AGTCTGTAACCTTGCCTAGTAATCGAACTTCTGCTGGAACATCTTCTTCAGGAGTATCCAATAGAAAAAGGAAAAGAAAAGTGTTTAGTC
CTATTCGATCTGAACCAAGATCTCCTTCTCACTCCATGAGGACAAGAAGTGGAAGGCTTAGTAGTTCTGAGCTCTCACCTCTCACCCCCC
CGTCTTCTGTCTCTTCCTCGTTAAGCATTTCTGTTAGTCCTCTTGCCACTAGTGCCTTAAACCCAACTTTTACTTTTCCTTCTCATTCCC
TGACTCAGTCTGGGGAATCTGCAGAGAAAAATCAGAGACCAAGGAAGCAGACTAGTGCTCCGGCAGAGCCATTTTCATCAAGTAGTCCTA
CTCCTCTCTTCCCTTGGTTTACCCCAGGCTCTCAGACTGAAAGAGGGAGAAATAAAGACAAGGCCCCCGAGGAGCTGTCCAAAGATCGAG
ATGCTGACAAGAGCGTGGAGAAGGACAAGAGTAGAGAGAGAGACCGGGAGAGAGAAAAGGAGAATAAGCGGGAGTCAAGGAAAGAGAAAA
GGAAAAAGGGATCAGAAATTCAGAGTAGTTCTGCTTTGTATCCTGTGGGTAGGGTTTCCAAAGAGAAGGTTGTTGGTGAAGATGTTGCCA
CTTCATCTTCTGCCAAAAAAGCAACAGGGCGGAAGAAGTCTTCATCACATGATTCTGGGACTGATATTACTTCTGTGACTCTTGGGGATA
CAACAGCTGTCAAAACCAAAATACTTATAAAGAAAGGGAGAGGAAATCTGGAAAAAACCAACTTGGACCTCGGCCCAACTGCCCCATCCC
TGGAGAAGGAGAAAACCCTCTGCCTTTCCACTCCTTCATCTAGCACTGTTAAACATTCCACTTCCTCCATAGGCTCCATGTTGGCTCAGG
CAGACAAGCTTCCAATGACTGACAAGAGGGTTGCCAGCCTCCTAAAAAAGGCCAAAGCTCAGCTCTGCAAGATTGAGAAGAGTAAGAGTC
TTAAACAAACCGACCAGCCCAAAGCACAGGGTCAAGAAAGTGACTCATCAGAGACCTCTGTGCGAGGACCCCGGATTAAACATGTCTGCA
GAAGAGCAGCTGTTGCCCTTGGCCGAAAACGAGCTGTGTTTCCTGATGACATGCCCACCCTGAGTGCCTTACCATGGGAAGAACGAGAAA
AGATTTTGTCTTCCATGGGGAATGATGACAAGTCATCAATTGCTGGCTCAGAAGATGCTGAACCTCTTGCTCCACCCATCAAACCAATTA
AACCTGTCACTAGAAACAAGGCACCCCAGGAACCTCCAGTAAAGAAAGGACGTCGATCGAGGCGGTGTGGGCAGTGTCCCGGCTGCCAGG
TGCCTGAGGACTGTGGTGTTTGTACTAATTGCTTAGATAAGCCCAAGTTTGGTGGTCGCAATATAAAGAAGCAGTGCTGCAAGATGAGAA
AATGTCAGAATCTACAATGGATGCCTTCCAAAGCCTACCTGCAGAAGCAAGCTAAAGCTGTGAAAAAGAAAGAGAAAAAGTCTAAGACCA
GTGAAAAGAAAGACAGCAAAGAGAGCAGTGTTGTGAAGAACGTGGTGGACTCTAGTCAGAAACCTACCCCATCAGCAAGAGAGGATCCTG
CCCCAAAGAAAAGCAGTAGTGAGCCTCCTCCACGAAAGCCCGTCGAGGAAAAGAGTGAAGAAGGGAATGTCTCGGCCCCTGGGCCTGAAT
CCAAACAGGCCACCACTCCAGCTTCCAGGAAGTCAAGCAAGCAGGTCTCCCAGCCAGCACTGGTCATCCCGCCTCAGCCACCTACTACAG
GACCGCCAAGAAAAGAAGTTCCCAAAACCACTCCTAGTGAGCCCAAGAAAAAGCAGCCTCCACCACCAGAATCAGGTCCAGAGCAGAGCA
AACAGAAAAAAGTGGCTCCCCGCCCAAGTATCCCTGTAAAACAAAAACCAAAAGAAAAGGAGATGACCTGGCTTCCACCACTTTCTGCTA
TTCAAGCACCTGGCAAAGTGGAACCAACCAAATTTCCATTTCCAAATAAGGACTCTCAGCTTGTATCCTCTGGACACAATAATCCAAAGA
AAGGTGATGCAGAGCCAGAGAGTCCAGACAGTGGCACATCGAATACATCAATGCTGGAAGATGACCTTAAGCTAAGCAGTGATGAAGAGG
AGAATGAACAGCAGGCAGCTCAGAGAACGGCTCTCCGCGCTCTCTCTGACAGCGCCGTGGTCCAGCAGCCCAACTGCAGAACCTCGGTGC
CTTCCAGCAAGGGCAGCAGCAGCAGCAGCAGCAGCGGCAGCAGCAGCTCCTCCAGCGACTCAGAGAGCAGCTCCGGATCTGACTCGGAGA
CCGAGAGCAGCTCCAGCGAGAGTGAGGGCAGCAAGCCCCCCCACTTCTCCAGCCCCGAGGCTGAACCGGCATCCTCTAACAAGTGGCAGC
TGGATAAATGGCTAAACAAAGTTAATCCCCACAAGCCTCCTATTCTGATCCAAAATGAAAGCCACGGGTCAGAGAGCAATCAGTACTACA
ACCCGGTGAAAGAGGACGTCCAGGACTGTGGGAAAGTCCCCGACGTTTGCCAGCCCAGCCTGAGAGAGAAGGAGATCAAGAGCACTTGCA
AGGAGGAGCAAAGGCCAAGGACAGCCAACAAGGCCCCTGGGAGTAAAGGCGTGAAGCAGAAGTCCCCGCCCGCGGCCGTGGCCGTGGCGG
TGAGCGCAGCCGCCCCGCCACCCGCAGTGCCCTGTGCGCCCGCGGAGAACGCGCCCGCGCCTGCCCGGAGGTCCGCGGGCAAGAAGCCCA
CCAGGCGCACCGAGAGGACCTCAGCCGGGGACGGCGCCAACTGCCACCGGCCCGAGGAGCCCGCGGCCGCGGACGCGCTGGGGACGAGCG
TGGTGGTCCCCCCGGAGCCCACCAAAACCAGGCCCTGTGGCAACAACAGAGCGAGCCACCGCAAGGAGCTGCGCTCCTCCGTGACCTGCG
AGAAGCGCCGCACGCGGGGGCTAAGCAGGATCGTCCCCAAATCCAAGGAGTTCATTGAGACAGAGTCGTCATCTTCATCCTCCTCCTCGG
ACTCCGACCTGGAGTCCGAGCAGGAGGAGTACCCTCTGTCCAAAGCACAGACCGTGGCTGCCTCTGCCTCCTCCGGGAATGATCAGAGGC
TGAAGGAGGCCGCTGCCAACGGGGGCAGTGGTCCTAGGGCCCCTGTAGGCTCCATCAACGCCAGGACCACCAGTGACATCGCCAAGGAGC
TGGAGGAGCAGTTCTACACACTGGTCCCCTTTGGCCGGAACGAACTTCTCTCCCCTCTAAAGGACAGTGATGAGATCAGGTCTCTCTGGG
TCAAAATCGACCTGACCCTCCTGTCCAGGATCCCAGAACACCTGCCCCAGGAGCCAGGGGTATTGAGCGCCCCTGCCACCAAGGACTCTG
AGAGCGCACCGCCCAGCCACACCTCGGACACACCTGCAGAAAAGGCTTTGCCAAAATCCAAGAGGAAACGCAAGTGTGACAACGAAGACG
ACTACAGGGAGATCAAGAAGTCCCAGGGAGAGAAAGACAGCTCTTCAAGACTGGCCACCTCCACCAGTAATACTTTGTCTGCAAACCACT
GCAACATGAACATCAACAGTGTGGCAATACCAATAAATAAAAATGAAAAAATGCTTCGGTCGCCCATCTCACCCCTCTCTGATGCATCTA
AACACAAATACACCAGCGAGGACTTAACTTCTTCCAGCCGACCTAATGGCAACAGTTTGTTTACTTCAGCCTCTTCCAGCAAAAAGCCTA
AGGCCGACAGCCAGCTGCAGCCTCACGGCGGAGACCTCACGAAAGCAGCTCACAACAATTCTGAAAACATTCCCCTCCACAAGTCACGGC
CGCAGACGAAGCCGTGGTCTCCAGGCTCCAACGGCCACAGGGACTGCAAGAGGCAGAAACTTGTCTTCGATGATATGCCTCGCAGTGCCG
ATTATTTTATGCAAGAAGCTAAACGAATGAAGCATAAAGCAGATGCAATGGTGGAAAAGTTTGGAAAGGCTTTGAACTATGCTGAAGCAG
CATTGTCGTTTATCGAGTGTGGAAATGCAATGGAACAAGGCCCCATGGAATCCAAATCTCCTTATACGATGTATTCAGAAACAGTAGAGC
TCATCAGGTATGCTATGAGACTAAAAACCCACTCAGGCCCCAATGCCACACCAGAAGACAAACAACTGGCTGCATTATGTTACCGATGCC
TGGCCCTCCTGTACTGGCGGATGTTTCGACTCAAAAGGGACCACGCTGTAAAGTATTCAAAAGCACTAATCGACTATTTCAAGAACTCAT
CTAAAGCCGCCCAAGCCCCATCTCCGTGGGGGGCCAGTGGAAAGAGCACTGGAACCCCATCCCCCATGTCTCCCAACCCCTCTCCCGCCA
GCTCCGTGGGGTCTCAGGGCAGCCTCTCCAACGCCAGCGCCCTGTCCCCGTCGACCATCGTCAGCATCCCACAGCGCATCCACCAGATGG
CGGCCAACCACGTCAGCATCACCAACAGCATCCTGCACAGCTACGACTACTGGGAGATGGCCGACAACCTGGCCAAGGAAAACCGAGAAT
TCTTCAACGACCTGGATCTGCTCATGGGGCCGGTCACCCTGCACAGCAGCATGGAGCACCTGGTCCAGTACTCCCAACAGGGCCTGCACT
GGCTGCGGAACAGCGCCCACCTGTCATAGGGACCTCACCCTGGGGCCAGAGTGGGCTCTGGTCTCCACAGATGGCTCAACGTTTTTGGAC
ACTGTGCTACTGAAACTCCCAGCCACAGCATTTATCAGACTGCGGTGAACATTTCCTCAGCATTGAACAATGATCTTTTGCAGGGCATGT
GTGTTTGTATGTGTGGGTATATAAGAAGCCGCCTGTGTATGTGTGTAAGATACACAGCTCTTCAGAACACACCTTCTTTGTCTAGTTTCC
ATAATCCCAGGCTAGACAAAGTGATCAGAGGTTTCTGACTAGAGGAAGTACACACACACACACACACACACACACACACCGTACACTCAC
ACACAATCACAGACACACACTTTCTATTCCATTCCAGTGCTAAACCGTGACTTCTTAGAAAATTCAACCAAAATCTCATGGGTTAGTTAA
CCAGGTGCAATACAGCACACCAAAAGCTTGACTGCCAGTGAAGATGGACCTGCTCTTATACTGTTGATTACTTTCAGTATTAATATACTA
TTCCCCAATTATTTTTTGATTGGTATGTATTAATGGGTAATTGAATAATGAAAATAAGCCAGGTATTTTTGTGCCGGAAGTTTACTAGAT
TGCATGTTACCAAATACCCTGCTCTTCCTCTAATTCCCTTCCCCCATCTGACTCTATTATCAACTAAATGCATTCCAGGCAAACAGATGG
ACACTCACAGCCCTTCCCAGCCCCACCTCCAAGTAGTATGCAAATGGCACTGAGATTTAGCAAAAACGCGGCGTCTTTGAAAGTTAACAG
ACACTAAGGTAGCAGTGCCTGTGTGTTGGAGCTCAGTTAGGAGTTGAAGTTTTCTGCACCTGTGATAACAAGCCCACCAGCCACATGCAT
TTCTTCTTCCTGCCACTGTGACTCGGTGGCTGTAGAGCCACATGGCATTTGTCAGCCAATCTGTTTCAAGTCTTTTCTTTCCACCAATAG
CTTTCTTACAGATTTTCTTGGCTAAATGAGGCCATTACCTAGATTGTCCCTTCAGTAGGAGCCTGAATCCTTCGCTTACCAGGCTGAGAG
CTATTTGCCATGATAATGCTGATTCTCTCACTCCTCATGCAGAATGTGCACCTGCAGCCCTTTGATGCGTTTTGATTTGGGGGCGATTTT
TCAGGCTTTGATTAGCAGGCTGCTTGCAATGCAGAAGATCACAGTTCCTTTCTGGGGCAGCAGCAACCAGAGCCTCTTCCTGTGTCCTGT
GTGTCTGGTATGTTTACACCTTGCTCTGAGTTTTTCTCTTGTTTTCTTTTTTTAATTAAGTTTACATTTTAGTTTCTTTGACATCTTGTT
TACAGTTTTTGTCTGATGTTTTTTCTTTTGTAGTGTCTTATGCCCTAGATTTAGTCATCTTGTTAAATATATTTGGATATGAAATCTTGA
CGAAAAGAAAATAACTCCTGAAAAAGAGGGTCTATCTTGCCACACGTTAAAAACAAAAATAATGTCCTTGTGGCCTCTTACTTGATAAAG
TTGCACCAGGACGGTCTGAGAAAGGCAGGCGGTGTAATATGTGGTGCAATCCATTTTTTCAAGGTGATGACGGCACAAAATACTTAGACT
AGATGCTGATCCATAAACATTCACTGATATTCTTACAGGTTGGTTTGCAGTGTTAACATTTTTGTTAGCCTGATCTGTAGGTGGGAAGTA
AGATCATCATAATTCCTTAGCTCTGAGCACTGATTCAAAATTGTATAAATGACTGAACAACTTAGATGATTTGAAATTAATTGAAAATAA
GAAGGGCTTGTGGAATTTGCATTTGGCTTTGGCCTTCAAGCATTTGGAAATATTAAGAGAATTTCCATTTTACATGTCTCCAACTGGGGT
GCTTCTTACAACCCTTTCACTTTTTTTTTGAGACGAGTTTCGCTCTGTTGCCCAGGCTGGAGTGCAGTGGCACGATCTCGGCTCACTGCA
TCCTCTGCCTCCTGGGTTCAAGTGATTGTCCCGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGTGTGCACTACCATGCCCAGCTAATTT
TTGTGTTTTTAGTAGAGACTGGGTTTCACCATGTTGGCCAGGCTCGTCTCAAACTCCTGACCTCAGGTGATCTACCCGCCTCCACCTCCC
AAAGTGTTGTGATTACAGGCGTGAGCCACCACACCCAGCCCTTTCACTAATTTTTGGCAGAGTTCACAATCCCATCCTATGTCAGAAACT
TGAACCTAACTTAAGAAATTTTGAGTCATTTTTTTGGAGGACTGAGGCTTTGTTCTACCTACTCTTGAAGAATCCTGATGAAATATTCAA
ACACATAAAGGGATGGCCCTGGAGGTCTATCCTGCATACCTGGAGAGCTTCTCTGGTCCTGCCCACCTTGAAAGTTGCAGACTTTGTTGT
AACATCTATGTGATGAGCTTCCCTGTGAAGCCCCATTTGACAGGTGGGCCAGCAGTGTTTTATCAGCACTCTGATGGCCCACATTTCCCA
GGAAAACTTCTTGAAACTTACCGTTGTGGGCAGTGGTCAGAGCGTGTAGTTCTTATGACTGTCTTGTTTCATCTGTGGAGCACGTGTGGA
GCACGTTGGTACAGCAGTTTCTGTGGGGTTTGGCATGGGTGATTTTGGTTAGTAACCATCCTCCAATTGTTGCTTGTGAAAGTCATTCAT
AACTTGTTCCTTTTACTTAGTTTTGTTGTTACTGCTGTTGTTGTTGGTTTGGTTGGTTTTGAGACCGGGTCTGGCTCTGTAGCCCAAGCT
GGAATGCGGTGGCGCGATCATGGCTCCCTGCAGCCTCAAACTCCTGGGCTCAAGCAATCCTCCTGCCTCAGCCTCCCAAGCAGCTGGGAA
GATAGGCACGTGCCACCACACCCGGCTAATTTTTTCTTTATTTTTTTTGTAGAGATGGGGGTCTCACTATGTTGCCCAGGCTGGTCTCAA
ACTCCTGGGCTCAAGCGATCCTTTGGCCTCGGCCTCCCAAAGTGCATGAGCCACCATGCCTGGCCTGTTTAGTTTTGTTTCAAGTTGAAA
TACCTTTCTTGTGTTTTCTAATTAGAAAAGTAATATCTACTCATTGTAAAAACTCAAACAGTGCAGAAATGTAGAAAGTAGAAAGTGTAA
GTCCCTGGTTGTCCCTTCTGCCTGAGACAACCACTGCTCACAGTTTGATGTATATCCTTCCAGAGACTCTCAAATTTAAGCAAATAATTT
TTATTACCATGTCTTTTTATTTGAAGACGTACATTTGCCTCCAAAGTTCAACACAAGTTCAACTGACCATATCCTTCCATGACCTGAATA
GATGCTATCCTTTATCACGATGTTCAATTGCCTTTGAAAGAGAGTAGTCCAGGTATATTCCTGATCAAAATTTGGCATTTTTGATGATAC
TACTCTACACAGATCAGACTCATGTGCAGAATCGTGCCTGGAGAGAGAGGTTTGGTTAAGACAGAGATTTCTGGAAACATTCAAATTGCA
AATGGAAACTTGAAACCCACAATCTAATGAGGAATGTACTGGAAAAATAATCTGAAGAGTTGACAAATTGTGTACTAGATTGAACACATG
GAATGCAATGCAATGAGACTTTCTGCACTAAAACTTATCCTCATATGTACAACAATGATGTGTGTATTATATAACAGTGATGTGTACATT
TCTGACACCCCATACATAATATACACAGTTTGTATAAATGCATACATTTAAAAATATATATGTACAATACAGCTAACATAAAACTGTAGT
ACGCCTGAAGGATATTACTAGTGCCTAATATTGAGTATGAGTCACTGCGTGTTCGCATCAACTTGGAAGTGCAGTAATTGTTATAAAATT
AATCAGTGCAGCCAACATTATTTATGAATCACATCTTTGAAACTGTGCAGTAGCATATACATATATATTTTTAAATAACATTTTTCACAG
TTTTCCAGAGTTACTGTTGAAATCTGCATCACCAAAAAAAAAAAAAAGCAAGATTTTTTTAACAATGTAGACACTCTTCAGACCCAGTAA
TCTGCGTGTGATTTCCTATTTGTAGATTCCCAAGAGACTTTAGCAGTCACCAGCCTTAATGCATGTACAGGATATTATTGTGACTTAATT
TATCTGCAGTTTTTAATCCATGTGAAATTGGAATTTATAAACGGACTTGGATTAAACATGTCTGCCTTTCTAAGGTTGCAAATGTTACAT
TAAATGATTTATGTTGTAAATGAGAGAAGTTGAGTTGTACGTAAAAGACATCCACCAATTTCTGTGAATATTTTTACACGGAAACTTGAG
AATCAAAATACGTTCAAGTCAGTTGTTCTGGCTCCCAGTTTATAATCTCGAAAAGCAATCTTTTTGTTTCATAAATGGCTTAAATGTAGC
TCCCACAGATTATCAGTATGAAGTCTGACATTTTTCATGGAAAAGAAGTATGTTTTTCTTCATTATAACTATAGTTTACTATTTGTCTTT
GCTATTTCCTGATACATACACATACGCACACACGCGCGCACATGCATGCACGTATGCACATGCACGCTCCCAGTGTCCCAGTGAAGGCTC
AACAGGAAGCTTGAGAAGGTCATCTCAATGGCCACAGGGTTCCTGTTCAACCAGTAGCCCTGGGATGCCGCTTTGCTTGTCATTCTTTAG
TGTCACAAGTTAGTTCCCTGACTTGTGTGCAGTCAGGGAACTGCACACAACTGAAACCAACATGGTGGAATCATGTTTGCAATATTTGGT
TGAGTAAAATAAGATAATTTTGAACTAAAGAAGACGGAGGCATTAGACCAGTGGCTTGACATGAAGCATCCCCTATGTGGGAGGGTAAGT
TTGTTAACTTCATTTTTAGTCTTATCTCCAACCCTTTTCCTTATCCTCCTCCCCAAACTAAAGAAGCAGAAACAGCAACAAAAGCAAAAC
CATCCCTTCACCTGATCCAGCCCATGTCCTTAGATTCAAATATCCTTTGTCTTTTTCCCATTATACCATCTGACATAACTCACTCGTGTC
TAGAGAGAAAAATGCAGAAAGGGTTTGTTTGCAGATGGGCAGTTCAGTTGAGTCCTCATTAACCAGGCAGAGGGGTGCAGAAGAAGCCTG
ACTCAGGGTCACCATGGAGAACTCCTCATCCCAGAGATGGGTGGGACAGGAACTTGGCTTTGCTTCACCAACCACTGAGCTTGATACTCT
TTCAGAGGTGGTTTGTGCTAAGAAACACCCAGCAGTCTTTCAAGAACGTTCTCTTCTGTAGCTTTGCCTGCTACACAGCTGAAGTCTGTC
CCTATAAGAATTATATTTGTAAAAAGTAATACATTTTCGAAGAAACCCGGATCAAGTGGAATCTTGAAAGTTTTTTTAATGAAAGGGGAA
AAACAACCTGACCACATAAACTGCACTTCCAACCATTTGGAACCAGAGTTTATGTCCTCATTTTCCCATTCTCAGAAGAGCACAGTTTTT
CAATATTACAACTTCCTGGCAAATAGCACAAGAAATGTTCAGACTTGAGATTTGTGTTCCCTTTGTCCAGATTATTCTGTATATGTCACC

>In-frame_ENST00000534358_ENST00000409236_AF422798_KMT2A_chr11_118353211_+_AFF3_chr2_100368765_length(amino acids)=2281AA_start in transcript=23_stop in transcript=6868
MAHSCRWRFPARPGTTGGGGGGGRRGLGGAPRQRVPALLLPPGPPVGGGGPGAPPSPPAVAAAAAAAGSSGAGVPGGAAAASAASSSSAS
SSSSSSSSASSGPALLRVGPGFDAALQVSAAIGTNLRRFRAVFGESGGGGGSGEDEQFLGFGSDEEVRVRSPTRSPSVKTSPRKPRGRPR
SGSDRNSAILSDPSVFSPLNKSETKSGDKIKKKDSKSIEKKRGRPPTFPGVKIKITHGKDISELPKGNKEDSLKKIKRTPSATFQQATKI
KKLRAGKLSPLKSKFKTGKLQIGRKGVQIVRRRGRPPSTERIKTPSGLLINSELEKPQKVRKDKEGTPPLTKEDKTVVRQSPRRIKPVRI
IPSSKRTDATIAKQLLQRAKKGAQKKIEKEAAQLQGRKVKTQVKNIRQFIMPVVSAISSRIIKTPRRFIEDEDYDPPIKIARLESTPNSR
FSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGS
RTTKKLSTLQSAPQQQTSSSPPPPLLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQ
YFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSN
RTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESA
EKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQ
SSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKILIKKGRGNLEKTNLDLGPTAPSLEKEKTLC
LSTPSSSTVKHSTSSIGSMLAQADKLPMTDKRVASLLKKAKAQLCKIEKSKSLKQTDQPKAQGQESDSSETSVRGPRIKHVCRRAAVALG
RKRAVFPDDMPTLSALPWEEREKILSSMGNDDKSSIAGSEDAEPLAPPIKPIKPVTRNKAPQEPPVKKGRRSRRCGQCPGCQVPEDCGVC
TNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKSSSE
PPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPR
PSIPVKQKPKEKEMTWLPPLSAIQAPGKVEPTKFPFPNKDSQLVSSGHNNPKKGDAEPESPDSGTSNTSMLEDDLKLSSDEEENEQQAAQ
RTALRALSDSAVVQQPNCRTSVPSSKGSSSSSSSGSSSSSSDSESSSGSDSETESSSSESEGSKPPHFSSPEAEPASSNKWQLDKWLNKV
NPHKPPILIQNESHGSESNQYYNPVKEDVQDCGKVPDVCQPSLREKEIKSTCKEEQRPRTANKAPGSKGVKQKSPPAAVAVAVSAAAPPP
AVPCAPAENAPAPARRSAGKKPTRRTERTSAGDGANCHRPEEPAAADALGTSVVVPPEPTKTRPCGNNRASHRKELRSSVTCEKRRTRGL
SRIVPKSKEFIETESSSSSSSSDSDLESEQEEYPLSKAQTVAASASSGNDQRLKEAAANGGSGPRAPVGSINARTTSDIAKELEEQFYTL
VPFGRNELLSPLKDSDEIRSLWVKIDLTLLSRIPEHLPQEPGVLSAPATKDSESAPPSHTSDTPAEKALPKSKRKRKCDNEDDYREIKKS
QGEKDSSSRLATSTSNTLSANHCNMNINSVAIPINKNEKMLRSPISPLSDASKHKYTSEDLTSSSRPNGNSLFTSASSSKKPKADSQLQP
HGGDLTKAAHNNSENIPLHKSRPQTKPWSPGSNGHRDCKRQKLVFDDMPRSADYFMQEAKRMKHKADAMVEKFGKALNYAEAALSFIECG
NAMEQGPMESKSPYTMYSETVELIRYAMRLKTHSGPNATPEDKQLAALCYRCLALLYWRMFRLKRDHAVKYSKALIDYFKNSSKAAQAPS
PWGASGKSTGTPSPMSPNPSPASSVGSQGSLSNASALSPSTIVSIPQRIHQMAANHVSITNSILHSYDYWEMADNLAKENREFFNDLDLL

--------------------------------------------------------------
>In-frame_ENST00000534358_ENST00000356421_AF422798_KMT2A_chr11_118353211_+_AFF3_chr2_100368765_length(transcript)=11087nt_BP=4109nt
CTGCTTCACTTCACGGGGCGAACATGGCGCACAGCTGTCGGTGGCGCTTCCCCGCCCGACCCGGGACCACCGGGGGCGGCGGCGGCGGGG
GGCGCCGGGGCCTAGGGGGCGCCCCGCGGCAACGCGTCCCGGCCCTGCTGCTTCCCCCCGGGCCCCCGGTCGGCGGTGGCGGCCCCGGGG
CGCCCCCCTCCCCCCCGGCTGTGGCGGCCGCGGCGGCGGCGGCGGGAAGCAGCGGGGCTGGGGTTCCAGGGGGAGCGGCCGCCGCCTCAG
CAGCCTCCTCGTCGTCCGCCTCGTCTTCGTCTTCGTCATCGTCCTCAGCCTCTTCAGGGCCGGCCCTGCTCCGGGTGGGCCCGGGCTTCG
ACGCGGCGCTGCAGGTCTCGGCCGCCATCGGCACCAACCTGCGCCGGTTCCGGGCCGTGTTTGGGGAGAGCGGCGGGGGAGGCGGCAGCG
GAGAGGATGAGCAATTCTTAGGTTTTGGCTCAGATGAAGAAGTCAGAGTGCGAAGTCCCACAAGGTCTCCTTCAGTTAAAACTAGTCCTC
GAAAACCTCGTGGGAGACCTAGAAGTGGCTCTGACCGAAATTCAGCTATCCTCTCAGATCCATCTGTGTTTTCCCCTCTAAATAAATCAG
AGACCAAATCTGGAGATAAGATCAAGAAGAAAGATTCTAAAAGTATAGAAAAGAAGAGAGGAAGACCTCCCACCTTCCCTGGAGTAAAAA
TCAAAATAACACATGGAAAGGACATTTCAGAGTTACCAAAGGGAAACAAAGAAGATAGCCTGAAAAAAATTAAAAGGACACCTTCTGCTA
CGTTTCAGCAAGCCACAAAGATTAAAAAATTAAGAGCAGGTAAACTCTCTCCTCTCAAGTCTAAGTTTAAGACAGGGAAGCTTCAAATAG
GAAGGAAGGGGGTACAAATTGTACGACGGAGAGGAAGGCCTCCATCAACAGAAAGGATAAAGACCCCTTCGGGTCTCCTCATTAATTCTG
AACTGGAAAAGCCCCAGAAAGTCCGGAAAGACAAGGAAGGAACACCTCCACTTACAAAAGAAGATAAGACAGTTGTCAGACAAAGCCCTC
GAAGGATTAAGCCAGTTAGGATTATTCCTTCTTCAAAAAGGACAGATGCAACCATTGCTAAGCAACTCTTACAGAGGGCAAAAAAGGGGG
CTCAAAAGAAAATTGAAAAAGAAGCAGCTCAGCTGCAGGGAAGAAAGGTGAAGACACAGGTCAAAAATATTCGACAGTTCATCATGCCTG
TTGTCAGTGCTATCTCCTCGCGGATCATTAAGACCCCTCGGCGGTTTATAGAGGATGAGGATTATGACCCTCCAATTAAAATTGCCCGAT
TAGAGTCTACACCGAATAGTAGATTCAGTGCCCCGTCCTGTGGATCTTCTGAAAAATCAAGTGCAGCTTCTCAGCACTCCTCTCAAATGT
CTTCAGACTCCTCTCGATCTAGTAGCCCCAGTGTTGATACCTCCACAGACTCTCAGGCTTCTGAGGAGATTCAGGTACTTCCTGAGGAGC
GGAGCGATACCCCTGAAGTTCATCCTCCACTGCCCATTTCCCAGTCCCCAGAAAATGAGAGTAATGATAGGAGAAGCAGAAGGTATTCAG
TGTCGGAGAGAAGTTTTGGATCTAGAACGACGAAAAAATTATCAACTCTACAAAGTGCCCCCCAGCAGCAGACCTCCTCGTCTCCACCTC
CACCTCTGCTGACTCCACCGCCACCACTGCAGCCAGCCTCCAGTATCTCTGACCACACACCTTGGCTTATGCCTCCAACAATCCCCTTAG
CATCACCATTTTTGCCTGCTTCCACTGCTCCTATGCAAGGGAAGCGAAAATCTATTTTGCGAGAACCGACATTTAGGTGGACTTCTTTAA
AGCATTCTAGGTCAGAGCCACAATACTTTTCCTCAGCAAAGTATGCCAAAGAAGGTCTTATTCGCAAACCAATATTTGATAATTTCCGAC
CCCCTCCACTAACTCCCGAGGACGTTGGCTTTGCATCTGGTTTTTCTGCATCTGGTACCGCTGCTTCAGCCCGATTGTTTTCGCCACTCC
ATTCTGGAACAAGGTTTGATATGCACAAAAGGAGCCCTCTTCTGAGAGCTCCAAGATTTACTCCAAGTGAGGCTCACTCTAGAATATTTG
AGTCTGTAACCTTGCCTAGTAATCGAACTTCTGCTGGAACATCTTCTTCAGGAGTATCCAATAGAAAAAGGAAAAGAAAAGTGTTTAGTC
CTATTCGATCTGAACCAAGATCTCCTTCTCACTCCATGAGGACAAGAAGTGGAAGGCTTAGTAGTTCTGAGCTCTCACCTCTCACCCCCC
CGTCTTCTGTCTCTTCCTCGTTAAGCATTTCTGTTAGTCCTCTTGCCACTAGTGCCTTAAACCCAACTTTTACTTTTCCTTCTCATTCCC
TGACTCAGTCTGGGGAATCTGCAGAGAAAAATCAGAGACCAAGGAAGCAGACTAGTGCTCCGGCAGAGCCATTTTCATCAAGTAGTCCTA
CTCCTCTCTTCCCTTGGTTTACCCCAGGCTCTCAGACTGAAAGAGGGAGAAATAAAGACAAGGCCCCCGAGGAGCTGTCCAAAGATCGAG
ATGCTGACAAGAGCGTGGAGAAGGACAAGAGTAGAGAGAGAGACCGGGAGAGAGAAAAGGAGAATAAGCGGGAGTCAAGGAAAGAGAAAA
GGAAAAAGGGATCAGAAATTCAGAGTAGTTCTGCTTTGTATCCTGTGGGTAGGGTTTCCAAAGAGAAGGTTGTTGGTGAAGATGTTGCCA
CTTCATCTTCTGCCAAAAAAGCAACAGGGCGGAAGAAGTCTTCATCACATGATTCTGGGACTGATATTACTTCTGTGACTCTTGGGGATA
CAACAGCTGTCAAAACCAAAATACTTATAAAGAAAGGGAGAGGAAATCTGGAAAAAACCAACTTGGACCTCGGCCCAACTGCCCCATCCC
TGGAGAAGGAGAAAACCCTCTGCCTTTCCACTCCTTCATCTAGCACTGTTAAACATTCCACTTCCTCCATAGGCTCCATGTTGGCTCAGG
CAGACAAGCTTCCAATGACTGACAAGAGGGTTGCCAGCCTCCTAAAAAAGGCCAAAGCTCAGCTCTGCAAGATTGAGAAGAGTAAGAGTC
TTAAACAAACCGACCAGCCCAAAGCACAGGGTCAAGAAAGTGACTCATCAGAGACCTCTGTGCGAGGACCCCGGATTAAACATGTCTGCA
GAAGAGCAGCTGTTGCCCTTGGCCGAAAACGAGCTGTGTTTCCTGATGACATGCCCACCCTGAGTGCCTTACCATGGGAAGAACGAGAAA
AGATTTTGTCTTCCATGGGGAATGATGACAAGTCATCAATTGCTGGCTCAGAAGATGCTGAACCTCTTGCTCCACCCATCAAACCAATTA
AACCTGTCACTAGAAACAAGGCACCCCAGGAACCTCCAGTAAAGAAAGGACGTCGATCGAGGCGGTGTGGGCAGTGTCCCGGCTGCCAGG
TGCCTGAGGACTGTGGTGTTTGTACTAATTGCTTAGATAAGCCCAAGTTTGGTGGTCGCAATATAAAGAAGCAGTGCTGCAAGATGAGAA
AATGTCAGAATCTACAATGGATGCCTTCCAAAGCCTACCTGCAGAAGCAAGCTAAAGCTGTGAAAAAGAAAGAGAAAAAGTCTAAGACCA
GTGAAAAGAAAGACAGCAAAGAGAGCAGTGTTGTGAAGAACGTGGTGGACTCTAGTCAGAAACCTACCCCATCAGCAAGAGAGGATCCTG
CCCCAAAGAAAAGCAGTAGTGAGCCTCCTCCACGAAAGCCCGTCGAGGAAAAGAGTGAAGAAGGGAATGTCTCGGCCCCTGGGCCTGAAT
CCAAACAGGCCACCACTCCAGCTTCCAGGAAGTCAAGCAAGCAGGTCTCCCAGCCAGCACTGGTCATCCCGCCTCAGCCACCTACTACAG
GACCGCCAAGAAAAGAAGTTCCCAAAACCACTCCTAGTGAGCCCAAGAAAAAGCAGCCTCCACCACCAGAATCAGGTCCAGAGCAGAGCA
AACAGAAAAAAGTGGCTCCCCGCCCAAGTATCCCTGTAAAACAAAAACCAAAAGAAAAGGAGATGACCTGGCTTCCACCACTTTCTGCTA
TTCAAGCACCTGGCAAAGTGGAACCAACCAAATTTCCATTTCCAAATAAGGACTCTCAGCTTGTATCCTCTGGACACAATAATCCAAAGA
AAGGTGATGCAGAGCCAGAGAGTCCAGACAGTGGCACATCGAATACATCAATGCTGGAAGATGACCTTAAGCTAAGCAGTGATGAAGAGG
AGAATGAACAGCAGGCAGCTCAGAGAACGGCTCTCCGCGCTCTCTCTGACAGCGCCGTGGTCCAGCAGCCCAACTGCAGAACCTCGGTGC
CTTCCAGCAAGGGCAGCAGCAGCAGCAGCAGCAGCGGCAGCAGCAGCTCCTCCAGCGACTCAGAGAGCAGCTCCGGATCTGACTCGGAGA
CCGAGAGCAGCTCCAGCGAGAGTGAGGGCAGCAAGCCCCCCCACTTCTCCAGCCCCGAGGCTGAACCGGCATCCTCTAACAAGTGGCAGC
TGGATAAATGGCTAAACAAAGTTAATCCCCACAAGCCTCCTATTCTGATCCAAAATGAAAGCCACGGGTCAGAGAGCAATCAGTACTACA
ACCCGGTGAAAGAGGACGTCCAGGACTGTGGGAAAGTCCCCGACGTTTGCCAGCCCAGCCTGAGAGAGAAGGAGATCAAGAGCACTTGCA
AGGAGGAGCAAAGGCCAAGGACAGCCAACAAGGCCCCTGGGAGTAAAGGCGTGAAGCAGAAGTCCCCGCCCGCGGCCGTGGCCGTGGCGG
TGAGCGCAGCCGCCCCGCCACCCGCAGTGCCCTGTGCGCCCGCGGAGAACGCGCCCGCGCCTGCCCGGAGGTCCGCGGGCAAGAAGCCCA
CCAGGCGCACCGAGAGGACCTCAGCCGGGGACGGCGCCAACTGCCACCGGCCCGAGGAGCCCGCGGCCGCGGACGCGCTGGGGACGAGCG
TGGTGGTCCCCCCGGAGCCCACCAAAACCAGGCCCTGTGGCAACAACAGAGCGAGCCACCGCAAGGAGCTGCGCTCCTCCGTGACCTGCG
AGAAGCGCCGCACGCGGGGGCTAAGCAGGATCGTCCCCAAATCCAAGGAGTTCATTGAGACAGAGTCGTCATCTTCATCCTCCTCCTCGG
ACTCCGACCTGGAGTCCGAGCAGGAGGAGTACCCTCTGTCCAAAGCACAGACCGTGGCTGCCTCTGCCTCCTCCGGGAATGATCAGAGGC
TGAAGGAGGCCGCTGCCAACGGGGGCAGTGGTCCTAGGGCCCCTGTAGGCTCCATCAACGCCAGGACCACCAGTGACATCGCCAAGGAGC
TGGAGGAGCAGTTCTACACACTGGTCCCCTTTGGCCGGAACGAACTTCTCTCCCCTCTAAAGGACAGTGATGAGATCAGGTCTCTCTGGG
TCAAAATCGACCTGACCCTCCTGTCCAGGATCCCAGAACACCTGCCCCAGGAGCCAGGGGTATTGAGCGCCCCTGCCACCAAGGACTCTG
AGAGCGCACCGCCCAGCCACACCTCGGACACACCTGCAGAAAAGGCTTTGCCAAAATCCAAGAGGAAACGCAAGTGTGACAACGAAGACG
ACTACAGGGAGATCAAGAAGTCCCAGGGAGAGAAAGACAGCTCTTCAAGACTGGCCACCTCCACCAGTAATACTTTGTCTGCAAACCACT
GCAACATGAACATCAACAGTGTGGCAATACCAATAAATAAAAATGAAAAAATGCTTCGGTCGCCCATCTCACCCCTCTCTGATGCATCTA
AACACAAATACACCAGCGAGGACTTAACTTCTTCCAGCCGACCTAATGGCAACAGTTTGTTTACTTCAGCCTCTTCCAGCAAAAAGCCTA
AGGCCGACAGCCAGCTGCAGCCTCACGGCGGAGACCTCACGAAAGCAGCTCACAACAATTCTGAAAACATTCCCCTCCACAAGTCACGGC
CGCAGACGAAGCCGTGGTCTCCAGGCTCCAACGGCCACAGGGACTGCAAGAGGCAGAAACTTGTCTTCGATGATATGCCTCGCAGTGCCG
ATTATTTTATGCAAGAAGCTAAACGAATGAAGCATAAAGCAGATGCAATGGTGGAAAAGTTTGGAAAGGCTTTGAACTATGCTGAAGCAG
CATTGTCGTTTATCGAGTGTGGAAATGCAATGGAACAAGGCCCCATGGAATCCAAATCTCCTTATACGATGTATTCAGAAACAGTAGAGC
TCATCAGGTATGCTATGAGACTAAAAACCCACTCAGGCCCCAATGCCACACCAGAAGACAAACAACTGGCTGCATTATGTTACCGATGCC
TGGCCCTCCTGTACTGGCGGATGTTTCGACTCAAAAGGGACCACGCTGTAAAGTATTCAAAAGCACTAATCGACTATTTCAAGAACTCAT
CTAAAGCCGCCCAAGCCCCATCTCCGTGGGGGGCCAGTGGAAAGAGCACTGGAACCCCATCCCCCATGTCTCCCAACCCCTCTCCCGCCA
GCTCCGTGGGGTCTCAGGGCAGCCTCTCCAACGCCAGCGCCCTGTCCCCGTCGACCATCGTCAGCATCCCACAGCGCATCCACCAGATGG
CGGCCAACCACGTCAGCATCACCAACAGCATCCTGCACAGCTACGACTACTGGGAGATGGCCGACAACCTGGCCAAGGAAAACCGAGAAT
TCTTCAACGACCTGGATCTGCTCATGGGGCCGGTCACCCTGCACAGCAGCATGGAGCACCTGGTCCAGTACTCCCAACAGGGCCTGCACT
GGCTGCGGAACAGCGCCCACCTGTCATAGGGACCTCACCCTGGGGCCAGAGTGGGCTCTGGTCTCCACAGATGGCTCAACGTTTTTGGAC
ACTGTGCTACTGAAACTCCCAGCCACAGCATTTATCAGACTGCGGTGAACATTTCCTCAGCATTGAACAATGATCTTTTGCAGGGCATGT
GTGTTTGTATGTGTGGGTATATAAGAAGCCGCCTGTGTATGTGTGTAAGATACACAGCTCTTCAGAACACACCTTCTTTGTCTAGTTTCC
ATAATCCCAGGCTAGACAAAGTGATCAGAGGTTTCTGACTAGAGGAAGTACACACACACACACACACACACACACACACCGTACACTCAC
ACACAATCACAGACACACACTTTCTATTCCATTCCAGTGCTAAACCGTGACTTCTTAGAAAATTCAACCAAAATCTCATGGGTTAGTTAA
CCAGGTGCAATACAGCACACCAAAAGCTTGACTGCCAGTGAAGATGGACCTGCTCTTATACTGTTGATTACTTTCAGTATTAATATACTA
TTCCCCAATTATTTTTTGATTGGTATGTATTAATGGGTAATTGAATAATGAAAATAAGCCAGGTATTTTTGTGCCGGAAGTTTACTAGAT
TGCATGTTACCAAATACCCTGCTCTTCCTCTAATTCCCTTCCCCCATCTGACTCTATTATCAACTAAATGCATTCCAGGCAAACAGATGG
ACACTCACAGCCCTTCCCAGCCCCACCTCCAAGTAGTATGCAAATGGCACTGAGATTTAGCAAAAACGCGGCGTCTTTGAAAGTTAACAG
ACACTAAGGTAGCAGTGCCTGTGTGTTGGAGCTCAGTTAGGAGTTGAAGTTTTCTGCACCTGTGATAACAAGCCCACCAGCCACATGCAT
TTCTTCTTCCTGCCACTGTGACTCGGTGGCTGTAGAGCCACATGGCATTTGTCAGCCAATCTGTTTCAAGTCTTTTCTTTCCACCAATAG
CTTTCTTACAGATTTTCTTGGCTAAATGAGGCCATTACCTAGATTGTCCCTTCAGTAGGAGCCTGAATCCTTCGCTTACCAGGCTGAGAG
CTATTTGCCATGATAATGCTGATTCTCTCACTCCTCATGCAGAATGTGCACCTGCAGCCCTTTGATGCGTTTTGATTTGGGGGCGATTTT
TCAGGCTTTGATTAGCAGGCTGCTTGCAATGCAGAAGATCACAGTTCCTTTCTGGGGCAGCAGCAACCAGAGCCTCTTCCTGTGTCCTGT
GTGTCTGGTATGTTTACACCTTGCTCTGAGTTTTTCTCTTGTTTTCTTTTTTTAATTAAGTTTACATTTTAGTTTCTTTGACATCTTGTT
TACAGTTTTTGTCTGATGTTTTTTCTTTTGTAGTGTCTTATGCCCTAGATTTAGTCATCTTGTTAAATATATTTGGATATGAAATCTTGA
CGAAAAGAAAATAACTCCTGAAAAAGAGGGTCTATCTTGCCACACGTTAAAAACAAAAATAATGTCCTTGTGGCCTCTTACTTGATAAAG
TTGCACCAGGACGGTCTGAGAAAGGCAGGCGGTGTAATATGTGGTGCAATCCATTTTTTCAAGGTGATGACGGCACAAAATACTTAGACT
AGATGCTGATCCATAAACATTCACTGATATTCTTACAGGTTGGTTTGCAGTGTTAACATTTTTGTTAGCCTGATCTGTAGGTGGGAAGTA
AGATCATCATAATTCCTTAGCTCTGAGCACTGATTCAAAATTGTATAAATGACTGAACAACTTAGATGATTTGAAATTAATTGAAAATAA
GAAGGGCTTGTGGAATTTGCATTTGGCTTTGGCCTTCAAGCATTTGGAAATATTAAGAGAATTTCCATTTTACATGTCTCCAACTGGGGT
GCTTCTTACAACCCTTTCACTTTTTTTTTGAGACGAGTTTCGCTCTGTTGCCCAGGCTGGAGTGCAGTGGCACGATCTCGGCTCACTGCA
TCCTCTGCCTCCTGGGTTCAAGTGATTGTCCCGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGTGTGCACTACCATGCCCAGCTAATTT
TTGTGTTTTTAGTAGAGACTGGGTTTCACCATGTTGGCCAGGCTCGTCTCAAACTCCTGACCTCAGGTGATCTACCCGCCTCCACCTCCC
AAAGTGTTGTGATTACAGGCGTGAGCCACCACACCCAGCCCTTTCACTAATTTTTGGCAGAGTTCACAATCCCATCCTATGTCAGAAACT
TGAACCTAACTTAAGAAATTTTGAGTCATTTTTTTGGAGGACTGAGGCTTTGTTCTACCTACTCTTGAAGAATCCTGATGAAATATTCAA
ACACATAAAGGGATGGCCCTGGAGGTCTATCCTGCATACCTGGAGAGCTTCTCTGGTCCTGCCCACCTTGAAAGTTGCAGACTTTGTTGT
AACATCTATGTGATGAGCTTCCCTGTGAAGCCCCATTTGACAGGTGGGCCAGCAGTGTTTTATCAGCACTCTGATGGCCCACATTTCCCA
GGAAAACTTCTTGAAACTTACCGTTGTGGGCAGTGGTCAGAGCGTGTAGTTCTTATGACTGTCTTGTTTCATCTGTGGAGCACGTGTGGA
GCACGTTGGTACAGCAGTTTCTGTGGGGTTTGGCATGGGTGATTTTGGTTAGTAACCATCCTCCAATTGTTGCTTGTGAAAGTCATTCAT
AACTTGTTCCTTTTACTTAGTTTTGTTGTTACTGCTGTTGTTGTTGGTTTGGTTGGTTTTGAGACCGGGTCTGGCTCTGTAGCCCAAGCT
GGAATGCGGTGGCGCGATCATGGCTCCCTGCAGCCTCAAACTCCTGGGCTCAAGCAATCCTCCTGCCTCAGCCTCCCAAGCAGCTGGGAA
GATAGGCACGTGCCACCACACCCGGCTAATTTTTTCTTTATTTTTTTTGTAGAGATGGGGGTCTCACTATGTTGCCCAGGCTGGTCTCAA
ACTCCTGGGCTCAAGCGATCCTTTGGCCTCGGCCTCCCAAAGTGCATGAGCCACCATGCCTGGCCTGTTTAGTTTTGTTTCAAGTTGAAA
TACCTTTCTTGTGTTTTCTAATTAGAAAAGTAATATCTACTCATTGTAAAAACTCAAACAGTGCAGAAATGTAGAAAGTAGAAAGTGTAA
GTCCCTGGTTGTCCCTTCTGCCTGAGACAACCACTGCTCACAGTTTGATGTATATCCTTCCAGAGACTCTCAAATTTAAGCAAATAATTT
TTATTACCATGTCTTTTTATTTGAAGACGTACATTTGCCTCCAAAGTTCAACACAAGTTCAACTGACCATATCCTTCCATGACCTGAATA
GATGCTATCCTTTATCACGATGTTCAATTGCCTTTGAAAGAGAGTAGTCCAGGTATATTCCTGATCAAAATTTGGCATTTTTGATGATAC
TACTCTACACAGATCAGACTCATGTGCAGAATCGTGCCTGGAGAGAGAGGTTTGGTTAAGACAGAGATTTCTGGAAACATTCAAATTGCA
AATGGAAACTTGAAACCCACAATCTAATGAGGAATGTACTGGAAAAATAATCTGAAGAGTTGACAAATTGTGTACTAGATTGAACACATG
GAATGCAATGCAATGAGACTTTCTGCACTAAAACTTATCCTCATATGTACAACAATGATGTGTGTATTATATAACAGTGATGTGTACATT
TCTGACACCCCATACATAATATACACAGTTTGTATAAATGCATACATTTAAAAATATATATGTACAATACAGCTAACATAAAACTGTAGT
ACGCCTGAAGGATATTACTAGTGCCTAATATTGAGTATGAGTCACTGCGTGTTCGCATCAACTTGGAAGTGCAGTAATTGTTATAAAATT
AATCAGTGCAGCCAACATTATTTATGAATCACATCTTTGAAACTGTGCAGTAGCATATACATATATATTTTTAAATAACATTTTTCACAG
TTTTCCAGAGTTACTGTTGAAATCTGCATCACCAAAAAAAAAAAAAAGCAAGATTTTTTTAACAATGTAGACACTCTTCAGACCCAGTAA
TCTGCGTGTGATTTCCTATTTGTAGATTCCCAAGAGACTTTAGCAGTCACCAGCCTTAATGCATGTACAGGATATTATTGTGACTTAATT
TATCTGCAGTTTTTAATCCATGTGAAATTGGAATTTATAAACGGACTTGGATTAAACATGTCTGCCTTTCTAAGGTTGCAAATGTTACAT

>In-frame_ENST00000534358_ENST00000356421_AF422798_KMT2A_chr11_118353211_+_AFF3_chr2_100368765_length(amino acids)=2281AA_start in transcript=23_stop in transcript=6868
MAHSCRWRFPARPGTTGGGGGGGRRGLGGAPRQRVPALLLPPGPPVGGGGPGAPPSPPAVAAAAAAAGSSGAGVPGGAAAASAASSSSAS
SSSSSSSSASSGPALLRVGPGFDAALQVSAAIGTNLRRFRAVFGESGGGGGSGEDEQFLGFGSDEEVRVRSPTRSPSVKTSPRKPRGRPR
SGSDRNSAILSDPSVFSPLNKSETKSGDKIKKKDSKSIEKKRGRPPTFPGVKIKITHGKDISELPKGNKEDSLKKIKRTPSATFQQATKI
KKLRAGKLSPLKSKFKTGKLQIGRKGVQIVRRRGRPPSTERIKTPSGLLINSELEKPQKVRKDKEGTPPLTKEDKTVVRQSPRRIKPVRI
IPSSKRTDATIAKQLLQRAKKGAQKKIEKEAAQLQGRKVKTQVKNIRQFIMPVVSAISSRIIKTPRRFIEDEDYDPPIKIARLESTPNSR
FSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGS
RTTKKLSTLQSAPQQQTSSSPPPPLLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQ
YFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSN
RTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESA
EKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQ
SSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKILIKKGRGNLEKTNLDLGPTAPSLEKEKTLC
LSTPSSSTVKHSTSSIGSMLAQADKLPMTDKRVASLLKKAKAQLCKIEKSKSLKQTDQPKAQGQESDSSETSVRGPRIKHVCRRAAVALG
RKRAVFPDDMPTLSALPWEEREKILSSMGNDDKSSIAGSEDAEPLAPPIKPIKPVTRNKAPQEPPVKKGRRSRRCGQCPGCQVPEDCGVC
TNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKSSSE
PPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPR
PSIPVKQKPKEKEMTWLPPLSAIQAPGKVEPTKFPFPNKDSQLVSSGHNNPKKGDAEPESPDSGTSNTSMLEDDLKLSSDEEENEQQAAQ
RTALRALSDSAVVQQPNCRTSVPSSKGSSSSSSSGSSSSSSDSESSSGSDSETESSSSESEGSKPPHFSSPEAEPASSNKWQLDKWLNKV
NPHKPPILIQNESHGSESNQYYNPVKEDVQDCGKVPDVCQPSLREKEIKSTCKEEQRPRTANKAPGSKGVKQKSPPAAVAVAVSAAAPPP
AVPCAPAENAPAPARRSAGKKPTRRTERTSAGDGANCHRPEEPAAADALGTSVVVPPEPTKTRPCGNNRASHRKELRSSVTCEKRRTRGL
SRIVPKSKEFIETESSSSSSSSDSDLESEQEEYPLSKAQTVAASASSGNDQRLKEAAANGGSGPRAPVGSINARTTSDIAKELEEQFYTL
VPFGRNELLSPLKDSDEIRSLWVKIDLTLLSRIPEHLPQEPGVLSAPATKDSESAPPSHTSDTPAEKALPKSKRKRKCDNEDDYREIKKS
QGEKDSSSRLATSTSNTLSANHCNMNINSVAIPINKNEKMLRSPISPLSDASKHKYTSEDLTSSSRPNGNSLFTSASSSKKPKADSQLQP
HGGDLTKAAHNNSENIPLHKSRPQTKPWSPGSNGHRDCKRQKLVFDDMPRSADYFMQEAKRMKHKADAMVEKFGKALNYAEAALSFIECG
NAMEQGPMESKSPYTMYSETVELIRYAMRLKTHSGPNATPEDKQLAALCYRCLALLYWRMFRLKRDHAVKYSKALIDYFKNSSKAAQAPS
PWGASGKSTGTPSPMSPNPSPASSVGSQGSLSNASALSPSTIVSIPQRIHQMAANHVSITNSILHSYDYWEMADNLAKENREFFNDLDLL

--------------------------------------------------------------
>In-frame_ENST00000534358_ENST00000317233_AF422798_KMT2A_chr11_118353211_+_AFF3_chr2_100368765_length(transcript)=11087nt_BP=4109nt
CTGCTTCACTTCACGGGGCGAACATGGCGCACAGCTGTCGGTGGCGCTTCCCCGCCCGACCCGGGACCACCGGGGGCGGCGGCGGCGGGG
GGCGCCGGGGCCTAGGGGGCGCCCCGCGGCAACGCGTCCCGGCCCTGCTGCTTCCCCCCGGGCCCCCGGTCGGCGGTGGCGGCCCCGGGG
CGCCCCCCTCCCCCCCGGCTGTGGCGGCCGCGGCGGCGGCGGCGGGAAGCAGCGGGGCTGGGGTTCCAGGGGGAGCGGCCGCCGCCTCAG
CAGCCTCCTCGTCGTCCGCCTCGTCTTCGTCTTCGTCATCGTCCTCAGCCTCTTCAGGGCCGGCCCTGCTCCGGGTGGGCCCGGGCTTCG
ACGCGGCGCTGCAGGTCTCGGCCGCCATCGGCACCAACCTGCGCCGGTTCCGGGCCGTGTTTGGGGAGAGCGGCGGGGGAGGCGGCAGCG
GAGAGGATGAGCAATTCTTAGGTTTTGGCTCAGATGAAGAAGTCAGAGTGCGAAGTCCCACAAGGTCTCCTTCAGTTAAAACTAGTCCTC
GAAAACCTCGTGGGAGACCTAGAAGTGGCTCTGACCGAAATTCAGCTATCCTCTCAGATCCATCTGTGTTTTCCCCTCTAAATAAATCAG
AGACCAAATCTGGAGATAAGATCAAGAAGAAAGATTCTAAAAGTATAGAAAAGAAGAGAGGAAGACCTCCCACCTTCCCTGGAGTAAAAA
TCAAAATAACACATGGAAAGGACATTTCAGAGTTACCAAAGGGAAACAAAGAAGATAGCCTGAAAAAAATTAAAAGGACACCTTCTGCTA
CGTTTCAGCAAGCCACAAAGATTAAAAAATTAAGAGCAGGTAAACTCTCTCCTCTCAAGTCTAAGTTTAAGACAGGGAAGCTTCAAATAG
GAAGGAAGGGGGTACAAATTGTACGACGGAGAGGAAGGCCTCCATCAACAGAAAGGATAAAGACCCCTTCGGGTCTCCTCATTAATTCTG
AACTGGAAAAGCCCCAGAAAGTCCGGAAAGACAAGGAAGGAACACCTCCACTTACAAAAGAAGATAAGACAGTTGTCAGACAAAGCCCTC
GAAGGATTAAGCCAGTTAGGATTATTCCTTCTTCAAAAAGGACAGATGCAACCATTGCTAAGCAACTCTTACAGAGGGCAAAAAAGGGGG
CTCAAAAGAAAATTGAAAAAGAAGCAGCTCAGCTGCAGGGAAGAAAGGTGAAGACACAGGTCAAAAATATTCGACAGTTCATCATGCCTG
TTGTCAGTGCTATCTCCTCGCGGATCATTAAGACCCCTCGGCGGTTTATAGAGGATGAGGATTATGACCCTCCAATTAAAATTGCCCGAT
TAGAGTCTACACCGAATAGTAGATTCAGTGCCCCGTCCTGTGGATCTTCTGAAAAATCAAGTGCAGCTTCTCAGCACTCCTCTCAAATGT
CTTCAGACTCCTCTCGATCTAGTAGCCCCAGTGTTGATACCTCCACAGACTCTCAGGCTTCTGAGGAGATTCAGGTACTTCCTGAGGAGC
GGAGCGATACCCCTGAAGTTCATCCTCCACTGCCCATTTCCCAGTCCCCAGAAAATGAGAGTAATGATAGGAGAAGCAGAAGGTATTCAG
TGTCGGAGAGAAGTTTTGGATCTAGAACGACGAAAAAATTATCAACTCTACAAAGTGCCCCCCAGCAGCAGACCTCCTCGTCTCCACCTC
CACCTCTGCTGACTCCACCGCCACCACTGCAGCCAGCCTCCAGTATCTCTGACCACACACCTTGGCTTATGCCTCCAACAATCCCCTTAG
CATCACCATTTTTGCCTGCTTCCACTGCTCCTATGCAAGGGAAGCGAAAATCTATTTTGCGAGAACCGACATTTAGGTGGACTTCTTTAA
AGCATTCTAGGTCAGAGCCACAATACTTTTCCTCAGCAAAGTATGCCAAAGAAGGTCTTATTCGCAAACCAATATTTGATAATTTCCGAC
CCCCTCCACTAACTCCCGAGGACGTTGGCTTTGCATCTGGTTTTTCTGCATCTGGTACCGCTGCTTCAGCCCGATTGTTTTCGCCACTCC
ATTCTGGAACAAGGTTTGATATGCACAAAAGGAGCCCTCTTCTGAGAGCTCCAAGATTTACTCCAAGTGAGGCTCACTCTAGAATATTTG
AGTCTGTAACCTTGCCTAGTAATCGAACTTCTGCTGGAACATCTTCTTCAGGAGTATCCAATAGAAAAAGGAAAAGAAAAGTGTTTAGTC
CTATTCGATCTGAACCAAGATCTCCTTCTCACTCCATGAGGACAAGAAGTGGAAGGCTTAGTAGTTCTGAGCTCTCACCTCTCACCCCCC
CGTCTTCTGTCTCTTCCTCGTTAAGCATTTCTGTTAGTCCTCTTGCCACTAGTGCCTTAAACCCAACTTTTACTTTTCCTTCTCATTCCC
TGACTCAGTCTGGGGAATCTGCAGAGAAAAATCAGAGACCAAGGAAGCAGACTAGTGCTCCGGCAGAGCCATTTTCATCAAGTAGTCCTA
CTCCTCTCTTCCCTTGGTTTACCCCAGGCTCTCAGACTGAAAGAGGGAGAAATAAAGACAAGGCCCCCGAGGAGCTGTCCAAAGATCGAG
ATGCTGACAAGAGCGTGGAGAAGGACAAGAGTAGAGAGAGAGACCGGGAGAGAGAAAAGGAGAATAAGCGGGAGTCAAGGAAAGAGAAAA
GGAAAAAGGGATCAGAAATTCAGAGTAGTTCTGCTTTGTATCCTGTGGGTAGGGTTTCCAAAGAGAAGGTTGTTGGTGAAGATGTTGCCA
CTTCATCTTCTGCCAAAAAAGCAACAGGGCGGAAGAAGTCTTCATCACATGATTCTGGGACTGATATTACTTCTGTGACTCTTGGGGATA
CAACAGCTGTCAAAACCAAAATACTTATAAAGAAAGGGAGAGGAAATCTGGAAAAAACCAACTTGGACCTCGGCCCAACTGCCCCATCCC
TGGAGAAGGAGAAAACCCTCTGCCTTTCCACTCCTTCATCTAGCACTGTTAAACATTCCACTTCCTCCATAGGCTCCATGTTGGCTCAGG
CAGACAAGCTTCCAATGACTGACAAGAGGGTTGCCAGCCTCCTAAAAAAGGCCAAAGCTCAGCTCTGCAAGATTGAGAAGAGTAAGAGTC
TTAAACAAACCGACCAGCCCAAAGCACAGGGTCAAGAAAGTGACTCATCAGAGACCTCTGTGCGAGGACCCCGGATTAAACATGTCTGCA
GAAGAGCAGCTGTTGCCCTTGGCCGAAAACGAGCTGTGTTTCCTGATGACATGCCCACCCTGAGTGCCTTACCATGGGAAGAACGAGAAA
AGATTTTGTCTTCCATGGGGAATGATGACAAGTCATCAATTGCTGGCTCAGAAGATGCTGAACCTCTTGCTCCACCCATCAAACCAATTA
AACCTGTCACTAGAAACAAGGCACCCCAGGAACCTCCAGTAAAGAAAGGACGTCGATCGAGGCGGTGTGGGCAGTGTCCCGGCTGCCAGG
TGCCTGAGGACTGTGGTGTTTGTACTAATTGCTTAGATAAGCCCAAGTTTGGTGGTCGCAATATAAAGAAGCAGTGCTGCAAGATGAGAA
AATGTCAGAATCTACAATGGATGCCTTCCAAAGCCTACCTGCAGAAGCAAGCTAAAGCTGTGAAAAAGAAAGAGAAAAAGTCTAAGACCA
GTGAAAAGAAAGACAGCAAAGAGAGCAGTGTTGTGAAGAACGTGGTGGACTCTAGTCAGAAACCTACCCCATCAGCAAGAGAGGATCCTG
CCCCAAAGAAAAGCAGTAGTGAGCCTCCTCCACGAAAGCCCGTCGAGGAAAAGAGTGAAGAAGGGAATGTCTCGGCCCCTGGGCCTGAAT
CCAAACAGGCCACCACTCCAGCTTCCAGGAAGTCAAGCAAGCAGGTCTCCCAGCCAGCACTGGTCATCCCGCCTCAGCCACCTACTACAG
GACCGCCAAGAAAAGAAGTTCCCAAAACCACTCCTAGTGAGCCCAAGAAAAAGCAGCCTCCACCACCAGAATCAGGTCCAGAGCAGAGCA
AACAGAAAAAAGTGGCTCCCCGCCCAAGTATCCCTGTAAAACAAAAACCAAAAGAAAAGGAGATGACCTGGCTTCCACCACTTTCTGCTA
TTCAAGCACCTGGCAAAGTGGAACCAACCAAATTTCCATTTCCAAATAAGGACTCTCAGCTTGTATCCTCTGGACACAATAATCCAAAGA
AAGGTGATGCAGAGCCAGAGAGTCCAGACAGTGGCACATCGAATACATCAATGCTGGAAGATGACCTTAAGCTAAGCAGTGATGAAGAGG
AGAATGAACAGCAGGCAGCTCAGAGAACGGCTCTCCGCGCTCTCTCTGACAGCGCCGTGGTCCAGCAGCCCAACTGCAGAACCTCGGTGC
CTTCCAGCAAGGGCAGCAGCAGCAGCAGCAGCAGCGGCAGCAGCAGCTCCTCCAGCGACTCAGAGAGCAGCTCCGGATCTGACTCGGAGA
CCGAGAGCAGCTCCAGCGAGAGTGAGGGCAGCAAGCCCCCCCACTTCTCCAGCCCCGAGGCTGAACCGGCATCCTCTAACAAGTGGCAGC
TGGATAAATGGCTAAACAAAGTTAATCCCCACAAGCCTCCTATTCTGATCCAAAATGAAAGCCACGGGTCAGAGAGCAATCAGTACTACA
ACCCGGTGAAAGAGGACGTCCAGGACTGTGGGAAAGTCCCCGACGTTTGCCAGCCCAGCCTGAGAGAGAAGGAGATCAAGAGCACTTGCA
AGGAGGAGCAAAGGCCAAGGACAGCCAACAAGGCCCCTGGGAGTAAAGGCGTGAAGCAGAAGTCCCCGCCCGCGGCCGTGGCCGTGGCGG
TGAGCGCAGCCGCCCCGCCACCCGCAGTGCCCTGTGCGCCCGCGGAGAACGCGCCCGCGCCTGCCCGGAGGTCCGCGGGCAAGAAGCCCA
CCAGGCGCACCGAGAGGACCTCAGCCGGGGACGGCGCCAACTGCCACCGGCCCGAGGAGCCCGCGGCCGCGGACGCGCTGGGGACGAGCG
TGGTGGTCCCCCCGGAGCCCACCAAAACCAGGCCCTGTGGCAACAACAGAGCGAGCCACCGCAAGGAGCTGCGCTCCTCCGTGACCTGCG
AGAAGCGCCGCACGCGGGGGCTAAGCAGGATCGTCCCCAAATCCAAGGAGTTCATTGAGACAGAGTCGTCATCTTCATCCTCCTCCTCGG
ACTCCGACCTGGAGTCCGAGCAGGAGGAGTACCCTCTGTCCAAAGCACAGACCGTGGCTGCCTCTGCCTCCTCCGGGAATGATCAGAGGC
TGAAGGAGGCCGCTGCCAACGGGGGCAGTGGTCCTAGGGCCCCTGTAGGCTCCATCAACGCCAGGACCACCAGTGACATCGCCAAGGAGC
TGGAGGAGCAGTTCTACACACTGGTCCCCTTTGGCCGGAACGAACTTCTCTCCCCTCTAAAGGACAGTGATGAGATCAGGTCTCTCTGGG
TCAAAATCGACCTGACCCTCCTGTCCAGGATCCCAGAACACCTGCCCCAGGAGCCAGGGGTATTGAGCGCCCCTGCCACCAAGGACTCTG
AGAGCGCACCGCCCAGCCACACCTCGGACACACCTGCAGAAAAGGCTTTGCCAAAATCCAAGAGGAAACGCAAGTGTGACAACGAAGACG
ACTACAGGGAGATCAAGAAGTCCCAGGGAGAGAAAGACAGCTCTTCAAGACTGGCCACCTCCACCAGTAATACTTTGTCTGCAAACCACT
GCAACATGAACATCAACAGTGTGGCAATACCAATAAATAAAAATGAAAAAATGCTTCGGTCGCCCATCTCACCCCTCTCTGATGCATCTA
AACACAAATACACCAGCGAGGACTTAACTTCTTCCAGCCGACCTAATGGCAACAGTTTGTTTACTTCAGCCTCTTCCAGCAAAAAGCCTA
AGGCCGACAGCCAGCTGCAGCCTCACGGCGGAGACCTCACGAAAGCAGCTCACAACAATTCTGAAAACATTCCCCTCCACAAGTCACGGC
CGCAGACGAAGCCGTGGTCTCCAGGCTCCAACGGCCACAGGGACTGCAAGAGGCAGAAACTTGTCTTCGATGATATGCCTCGCAGTGCCG
ATTATTTTATGCAAGAAGCTAAACGAATGAAGCATAAAGCAGATGCAATGGTGGAAAAGTTTGGAAAGGCTTTGAACTATGCTGAAGCAG
CATTGTCGTTTATCGAGTGTGGAAATGCAATGGAACAAGGCCCCATGGAATCCAAATCTCCTTATACGATGTATTCAGAAACAGTAGAGC
TCATCAGGTATGCTATGAGACTAAAAACCCACTCAGGCCCCAATGCCACACCAGAAGACAAACAACTGGCTGCATTATGTTACCGATGCC
TGGCCCTCCTGTACTGGCGGATGTTTCGACTCAAAAGGGACCACGCTGTAAAGTATTCAAAAGCACTAATCGACTATTTCAAGAACTCAT
CTAAAGCCGCCCAAGCCCCATCTCCGTGGGGGGCCAGTGGAAAGAGCACTGGAACCCCATCCCCCATGTCTCCCAACCCCTCTCCCGCCA
GCTCCGTGGGGTCTCAGGGCAGCCTCTCCAACGCCAGCGCCCTGTCCCCGTCGACCATCGTCAGCATCCCACAGCGCATCCACCAGATGG
CGGCCAACCACGTCAGCATCACCAACAGCATCCTGCACAGCTACGACTACTGGGAGATGGCCGACAACCTGGCCAAGGAAAACCGAGAAT
TCTTCAACGACCTGGATCTGCTCATGGGGCCGGTCACCCTGCACAGCAGCATGGAGCACCTGGTCCAGTACTCCCAACAGGGCCTGCACT
GGCTGCGGAACAGCGCCCACCTGTCATAGGGACCTCACCCTGGGGCCAGAGTGGGCTCTGGTCTCCACAGATGGCTCAACGTTTTTGGAC
ACTGTGCTACTGAAACTCCCAGCCACAGCATTTATCAGACTGCGGTGAACATTTCCTCAGCATTGAACAATGATCTTTTGCAGGGCATGT
GTGTTTGTATGTGTGGGTATATAAGAAGCCGCCTGTGTATGTGTGTAAGATACACAGCTCTTCAGAACACACCTTCTTTGTCTAGTTTCC
ATAATCCCAGGCTAGACAAAGTGATCAGAGGTTTCTGACTAGAGGAAGTACACACACACACACACACACACACACACACCGTACACTCAC
ACACAATCACAGACACACACTTTCTATTCCATTCCAGTGCTAAACCGTGACTTCTTAGAAAATTCAACCAAAATCTCATGGGTTAGTTAA
CCAGGTGCAATACAGCACACCAAAAGCTTGACTGCCAGTGAAGATGGACCTGCTCTTATACTGTTGATTACTTTCAGTATTAATATACTA
TTCCCCAATTATTTTTTGATTGGTATGTATTAATGGGTAATTGAATAATGAAAATAAGCCAGGTATTTTTGTGCCGGAAGTTTACTAGAT
TGCATGTTACCAAATACCCTGCTCTTCCTCTAATTCCCTTCCCCCATCTGACTCTATTATCAACTAAATGCATTCCAGGCAAACAGATGG
ACACTCACAGCCCTTCCCAGCCCCACCTCCAAGTAGTATGCAAATGGCACTGAGATTTAGCAAAAACGCGGCGTCTTTGAAAGTTAACAG
ACACTAAGGTAGCAGTGCCTGTGTGTTGGAGCTCAGTTAGGAGTTGAAGTTTTCTGCACCTGTGATAACAAGCCCACCAGCCACATGCAT
TTCTTCTTCCTGCCACTGTGACTCGGTGGCTGTAGAGCCACATGGCATTTGTCAGCCAATCTGTTTCAAGTCTTTTCTTTCCACCAATAG
CTTTCTTACAGATTTTCTTGGCTAAATGAGGCCATTACCTAGATTGTCCCTTCAGTAGGAGCCTGAATCCTTCGCTTACCAGGCTGAGAG
CTATTTGCCATGATAATGCTGATTCTCTCACTCCTCATGCAGAATGTGCACCTGCAGCCCTTTGATGCGTTTTGATTTGGGGGCGATTTT
TCAGGCTTTGATTAGCAGGCTGCTTGCAATGCAGAAGATCACAGTTCCTTTCTGGGGCAGCAGCAACCAGAGCCTCTTCCTGTGTCCTGT
GTGTCTGGTATGTTTACACCTTGCTCTGAGTTTTTCTCTTGTTTTCTTTTTTTAATTAAGTTTACATTTTAGTTTCTTTGACATCTTGTT
TACAGTTTTTGTCTGATGTTTTTTCTTTTGTAGTGTCTTATGCCCTAGATTTAGTCATCTTGTTAAATATATTTGGATATGAAATCTTGA
CGAAAAGAAAATAACTCCTGAAAAAGAGGGTCTATCTTGCCACACGTTAAAAACAAAAATAATGTCCTTGTGGCCTCTTACTTGATAAAG
TTGCACCAGGACGGTCTGAGAAAGGCAGGCGGTGTAATATGTGGTGCAATCCATTTTTTCAAGGTGATGACGGCACAAAATACTTAGACT
AGATGCTGATCCATAAACATTCACTGATATTCTTACAGGTTGGTTTGCAGTGTTAACATTTTTGTTAGCCTGATCTGTAGGTGGGAAGTA
AGATCATCATAATTCCTTAGCTCTGAGCACTGATTCAAAATTGTATAAATGACTGAACAACTTAGATGATTTGAAATTAATTGAAAATAA
GAAGGGCTTGTGGAATTTGCATTTGGCTTTGGCCTTCAAGCATTTGGAAATATTAAGAGAATTTCCATTTTACATGTCTCCAACTGGGGT
GCTTCTTACAACCCTTTCACTTTTTTTTTGAGACGAGTTTCGCTCTGTTGCCCAGGCTGGAGTGCAGTGGCACGATCTCGGCTCACTGCA
TCCTCTGCCTCCTGGGTTCAAGTGATTGTCCCGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGTGTGCACTACCATGCCCAGCTAATTT
TTGTGTTTTTAGTAGAGACTGGGTTTCACCATGTTGGCCAGGCTCGTCTCAAACTCCTGACCTCAGGTGATCTACCCGCCTCCACCTCCC
AAAGTGTTGTGATTACAGGCGTGAGCCACCACACCCAGCCCTTTCACTAATTTTTGGCAGAGTTCACAATCCCATCCTATGTCAGAAACT
TGAACCTAACTTAAGAAATTTTGAGTCATTTTTTTGGAGGACTGAGGCTTTGTTCTACCTACTCTTGAAGAATCCTGATGAAATATTCAA
ACACATAAAGGGATGGCCCTGGAGGTCTATCCTGCATACCTGGAGAGCTTCTCTGGTCCTGCCCACCTTGAAAGTTGCAGACTTTGTTGT
AACATCTATGTGATGAGCTTCCCTGTGAAGCCCCATTTGACAGGTGGGCCAGCAGTGTTTTATCAGCACTCTGATGGCCCACATTTCCCA
GGAAAACTTCTTGAAACTTACCGTTGTGGGCAGTGGTCAGAGCGTGTAGTTCTTATGACTGTCTTGTTTCATCTGTGGAGCACGTGTGGA
GCACGTTGGTACAGCAGTTTCTGTGGGGTTTGGCATGGGTGATTTTGGTTAGTAACCATCCTCCAATTGTTGCTTGTGAAAGTCATTCAT
AACTTGTTCCTTTTACTTAGTTTTGTTGTTACTGCTGTTGTTGTTGGTTTGGTTGGTTTTGAGACCGGGTCTGGCTCTGTAGCCCAAGCT
GGAATGCGGTGGCGCGATCATGGCTCCCTGCAGCCTCAAACTCCTGGGCTCAAGCAATCCTCCTGCCTCAGCCTCCCAAGCAGCTGGGAA
GATAGGCACGTGCCACCACACCCGGCTAATTTTTTCTTTATTTTTTTTGTAGAGATGGGGGTCTCACTATGTTGCCCAGGCTGGTCTCAA
ACTCCTGGGCTCAAGCGATCCTTTGGCCTCGGCCTCCCAAAGTGCATGAGCCACCATGCCTGGCCTGTTTAGTTTTGTTTCAAGTTGAAA
TACCTTTCTTGTGTTTTCTAATTAGAAAAGTAATATCTACTCATTGTAAAAACTCAAACAGTGCAGAAATGTAGAAAGTAGAAAGTGTAA
GTCCCTGGTTGTCCCTTCTGCCTGAGACAACCACTGCTCACAGTTTGATGTATATCCTTCCAGAGACTCTCAAATTTAAGCAAATAATTT
TTATTACCATGTCTTTTTATTTGAAGACGTACATTTGCCTCCAAAGTTCAACACAAGTTCAACTGACCATATCCTTCCATGACCTGAATA
GATGCTATCCTTTATCACGATGTTCAATTGCCTTTGAAAGAGAGTAGTCCAGGTATATTCCTGATCAAAATTTGGCATTTTTGATGATAC
TACTCTACACAGATCAGACTCATGTGCAGAATCGTGCCTGGAGAGAGAGGTTTGGTTAAGACAGAGATTTCTGGAAACATTCAAATTGCA
AATGGAAACTTGAAACCCACAATCTAATGAGGAATGTACTGGAAAAATAATCTGAAGAGTTGACAAATTGTGTACTAGATTGAACACATG
GAATGCAATGCAATGAGACTTTCTGCACTAAAACTTATCCTCATATGTACAACAATGATGTGTGTATTATATAACAGTGATGTGTACATT
TCTGACACCCCATACATAATATACACAGTTTGTATAAATGCATACATTTAAAAATATATATGTACAATACAGCTAACATAAAACTGTAGT
ACGCCTGAAGGATATTACTAGTGCCTAATATTGAGTATGAGTCACTGCGTGTTCGCATCAACTTGGAAGTGCAGTAATTGTTATAAAATT
AATCAGTGCAGCCAACATTATTTATGAATCACATCTTTGAAACTGTGCAGTAGCATATACATATATATTTTTAAATAACATTTTTCACAG
TTTTCCAGAGTTACTGTTGAAATCTGCATCACCAAAAAAAAAAAAAAGCAAGATTTTTTTAACAATGTAGACACTCTTCAGACCCAGTAA
TCTGCGTGTGATTTCCTATTTGTAGATTCCCAAGAGACTTTAGCAGTCACCAGCCTTAATGCATGTACAGGATATTATTGTGACTTAATT
TATCTGCAGTTTTTAATCCATGTGAAATTGGAATTTATAAACGGACTTGGATTAAACATGTCTGCCTTTCTAAGGTTGCAAATGTTACAT

>In-frame_ENST00000534358_ENST00000317233_AF422798_KMT2A_chr11_118353211_+_AFF3_chr2_100368765_length(amino acids)=2281AA_start in transcript=23_stop in transcript=6868
MAHSCRWRFPARPGTTGGGGGGGRRGLGGAPRQRVPALLLPPGPPVGGGGPGAPPSPPAVAAAAAAAGSSGAGVPGGAAAASAASSSSAS
SSSSSSSSASSGPALLRVGPGFDAALQVSAAIGTNLRRFRAVFGESGGGGGSGEDEQFLGFGSDEEVRVRSPTRSPSVKTSPRKPRGRPR
SGSDRNSAILSDPSVFSPLNKSETKSGDKIKKKDSKSIEKKRGRPPTFPGVKIKITHGKDISELPKGNKEDSLKKIKRTPSATFQQATKI
KKLRAGKLSPLKSKFKTGKLQIGRKGVQIVRRRGRPPSTERIKTPSGLLINSELEKPQKVRKDKEGTPPLTKEDKTVVRQSPRRIKPVRI
IPSSKRTDATIAKQLLQRAKKGAQKKIEKEAAQLQGRKVKTQVKNIRQFIMPVVSAISSRIIKTPRRFIEDEDYDPPIKIARLESTPNSR
FSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGS
RTTKKLSTLQSAPQQQTSSSPPPPLLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQ
YFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSN
RTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESA
EKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQ
SSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKILIKKGRGNLEKTNLDLGPTAPSLEKEKTLC
LSTPSSSTVKHSTSSIGSMLAQADKLPMTDKRVASLLKKAKAQLCKIEKSKSLKQTDQPKAQGQESDSSETSVRGPRIKHVCRRAAVALG
RKRAVFPDDMPTLSALPWEEREKILSSMGNDDKSSIAGSEDAEPLAPPIKPIKPVTRNKAPQEPPVKKGRRSRRCGQCPGCQVPEDCGVC
TNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKSSSE
PPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPR
PSIPVKQKPKEKEMTWLPPLSAIQAPGKVEPTKFPFPNKDSQLVSSGHNNPKKGDAEPESPDSGTSNTSMLEDDLKLSSDEEENEQQAAQ
RTALRALSDSAVVQQPNCRTSVPSSKGSSSSSSSGSSSSSSDSESSSGSDSETESSSSESEGSKPPHFSSPEAEPASSNKWQLDKWLNKV
NPHKPPILIQNESHGSESNQYYNPVKEDVQDCGKVPDVCQPSLREKEIKSTCKEEQRPRTANKAPGSKGVKQKSPPAAVAVAVSAAAPPP
AVPCAPAENAPAPARRSAGKKPTRRTERTSAGDGANCHRPEEPAAADALGTSVVVPPEPTKTRPCGNNRASHRKELRSSVTCEKRRTRGL
SRIVPKSKEFIETESSSSSSSSDSDLESEQEEYPLSKAQTVAASASSGNDQRLKEAAANGGSGPRAPVGSINARTTSDIAKELEEQFYTL
VPFGRNELLSPLKDSDEIRSLWVKIDLTLLSRIPEHLPQEPGVLSAPATKDSESAPPSHTSDTPAEKALPKSKRKRKCDNEDDYREIKKS
QGEKDSSSRLATSTSNTLSANHCNMNINSVAIPINKNEKMLRSPISPLSDASKHKYTSEDLTSSSRPNGNSLFTSASSSKKPKADSQLQP
HGGDLTKAAHNNSENIPLHKSRPQTKPWSPGSNGHRDCKRQKLVFDDMPRSADYFMQEAKRMKHKADAMVEKFGKALNYAEAALSFIECG
NAMEQGPMESKSPYTMYSETVELIRYAMRLKTHSGPNATPEDKQLAALCYRCLALLYWRMFRLKRDHAVKYSKALIDYFKNSSKAAQAPS
PWGASGKSTGTPSPMSPNPSPASSVGSQGSLSNASALSPSTIVSIPQRIHQMAANHVSITNSILHSYDYWEMADNLAKENREFFNDLDLL

--------------------------------------------------------------
>In-frame_ENST00000534358_ENST00000409579_AF422798_KMT2A_chr11_118353211_+_AFF3_chr2_100368765_length(transcript)=7222nt_BP=4109nt
CTGCTTCACTTCACGGGGCGAACATGGCGCACAGCTGTCGGTGGCGCTTCCCCGCCCGACCCGGGACCACCGGGGGCGGCGGCGGCGGGG
GGCGCCGGGGCCTAGGGGGCGCCCCGCGGCAACGCGTCCCGGCCCTGCTGCTTCCCCCCGGGCCCCCGGTCGGCGGTGGCGGCCCCGGGG
CGCCCCCCTCCCCCCCGGCTGTGGCGGCCGCGGCGGCGGCGGCGGGAAGCAGCGGGGCTGGGGTTCCAGGGGGAGCGGCCGCCGCCTCAG
CAGCCTCCTCGTCGTCCGCCTCGTCTTCGTCTTCGTCATCGTCCTCAGCCTCTTCAGGGCCGGCCCTGCTCCGGGTGGGCCCGGGCTTCG
ACGCGGCGCTGCAGGTCTCGGCCGCCATCGGCACCAACCTGCGCCGGTTCCGGGCCGTGTTTGGGGAGAGCGGCGGGGGAGGCGGCAGCG
GAGAGGATGAGCAATTCTTAGGTTTTGGCTCAGATGAAGAAGTCAGAGTGCGAAGTCCCACAAGGTCTCCTTCAGTTAAAACTAGTCCTC
GAAAACCTCGTGGGAGACCTAGAAGTGGCTCTGACCGAAATTCAGCTATCCTCTCAGATCCATCTGTGTTTTCCCCTCTAAATAAATCAG
AGACCAAATCTGGAGATAAGATCAAGAAGAAAGATTCTAAAAGTATAGAAAAGAAGAGAGGAAGACCTCCCACCTTCCCTGGAGTAAAAA
TCAAAATAACACATGGAAAGGACATTTCAGAGTTACCAAAGGGAAACAAAGAAGATAGCCTGAAAAAAATTAAAAGGACACCTTCTGCTA
CGTTTCAGCAAGCCACAAAGATTAAAAAATTAAGAGCAGGTAAACTCTCTCCTCTCAAGTCTAAGTTTAAGACAGGGAAGCTTCAAATAG
GAAGGAAGGGGGTACAAATTGTACGACGGAGAGGAAGGCCTCCATCAACAGAAAGGATAAAGACCCCTTCGGGTCTCCTCATTAATTCTG
AACTGGAAAAGCCCCAGAAAGTCCGGAAAGACAAGGAAGGAACACCTCCACTTACAAAAGAAGATAAGACAGTTGTCAGACAAAGCCCTC
GAAGGATTAAGCCAGTTAGGATTATTCCTTCTTCAAAAAGGACAGATGCAACCATTGCTAAGCAACTCTTACAGAGGGCAAAAAAGGGGG
CTCAAAAGAAAATTGAAAAAGAAGCAGCTCAGCTGCAGGGAAGAAAGGTGAAGACACAGGTCAAAAATATTCGACAGTTCATCATGCCTG
TTGTCAGTGCTATCTCCTCGCGGATCATTAAGACCCCTCGGCGGTTTATAGAGGATGAGGATTATGACCCTCCAATTAAAATTGCCCGAT
TAGAGTCTACACCGAATAGTAGATTCAGTGCCCCGTCCTGTGGATCTTCTGAAAAATCAAGTGCAGCTTCTCAGCACTCCTCTCAAATGT
CTTCAGACTCCTCTCGATCTAGTAGCCCCAGTGTTGATACCTCCACAGACTCTCAGGCTTCTGAGGAGATTCAGGTACTTCCTGAGGAGC
GGAGCGATACCCCTGAAGTTCATCCTCCACTGCCCATTTCCCAGTCCCCAGAAAATGAGAGTAATGATAGGAGAAGCAGAAGGTATTCAG
TGTCGGAGAGAAGTTTTGGATCTAGAACGACGAAAAAATTATCAACTCTACAAAGTGCCCCCCAGCAGCAGACCTCCTCGTCTCCACCTC
CACCTCTGCTGACTCCACCGCCACCACTGCAGCCAGCCTCCAGTATCTCTGACCACACACCTTGGCTTATGCCTCCAACAATCCCCTTAG
CATCACCATTTTTGCCTGCTTCCACTGCTCCTATGCAAGGGAAGCGAAAATCTATTTTGCGAGAACCGACATTTAGGTGGACTTCTTTAA
AGCATTCTAGGTCAGAGCCACAATACTTTTCCTCAGCAAAGTATGCCAAAGAAGGTCTTATTCGCAAACCAATATTTGATAATTTCCGAC
CCCCTCCACTAACTCCCGAGGACGTTGGCTTTGCATCTGGTTTTTCTGCATCTGGTACCGCTGCTTCAGCCCGATTGTTTTCGCCACTCC
ATTCTGGAACAAGGTTTGATATGCACAAAAGGAGCCCTCTTCTGAGAGCTCCAAGATTTACTCCAAGTGAGGCTCACTCTAGAATATTTG
AGTCTGTAACCTTGCCTAGTAATCGAACTTCTGCTGGAACATCTTCTTCAGGAGTATCCAATAGAAAAAGGAAAAGAAAAGTGTTTAGTC
CTATTCGATCTGAACCAAGATCTCCTTCTCACTCCATGAGGACAAGAAGTGGAAGGCTTAGTAGTTCTGAGCTCTCACCTCTCACCCCCC
CGTCTTCTGTCTCTTCCTCGTTAAGCATTTCTGTTAGTCCTCTTGCCACTAGTGCCTTAAACCCAACTTTTACTTTTCCTTCTCATTCCC
TGACTCAGTCTGGGGAATCTGCAGAGAAAAATCAGAGACCAAGGAAGCAGACTAGTGCTCCGGCAGAGCCATTTTCATCAAGTAGTCCTA
CTCCTCTCTTCCCTTGGTTTACCCCAGGCTCTCAGACTGAAAGAGGGAGAAATAAAGACAAGGCCCCCGAGGAGCTGTCCAAAGATCGAG
ATGCTGACAAGAGCGTGGAGAAGGACAAGAGTAGAGAGAGAGACCGGGAGAGAGAAAAGGAGAATAAGCGGGAGTCAAGGAAAGAGAAAA
GGAAAAAGGGATCAGAAATTCAGAGTAGTTCTGCTTTGTATCCTGTGGGTAGGGTTTCCAAAGAGAAGGTTGTTGGTGAAGATGTTGCCA
CTTCATCTTCTGCCAAAAAAGCAACAGGGCGGAAGAAGTCTTCATCACATGATTCTGGGACTGATATTACTTCTGTGACTCTTGGGGATA
CAACAGCTGTCAAAACCAAAATACTTATAAAGAAAGGGAGAGGAAATCTGGAAAAAACCAACTTGGACCTCGGCCCAACTGCCCCATCCC
TGGAGAAGGAGAAAACCCTCTGCCTTTCCACTCCTTCATCTAGCACTGTTAAACATTCCACTTCCTCCATAGGCTCCATGTTGGCTCAGG
CAGACAAGCTTCCAATGACTGACAAGAGGGTTGCCAGCCTCCTAAAAAAGGCCAAAGCTCAGCTCTGCAAGATTGAGAAGAGTAAGAGTC
TTAAACAAACCGACCAGCCCAAAGCACAGGGTCAAGAAAGTGACTCATCAGAGACCTCTGTGCGAGGACCCCGGATTAAACATGTCTGCA
GAAGAGCAGCTGTTGCCCTTGGCCGAAAACGAGCTGTGTTTCCTGATGACATGCCCACCCTGAGTGCCTTACCATGGGAAGAACGAGAAA
AGATTTTGTCTTCCATGGGGAATGATGACAAGTCATCAATTGCTGGCTCAGAAGATGCTGAACCTCTTGCTCCACCCATCAAACCAATTA
AACCTGTCACTAGAAACAAGGCACCCCAGGAACCTCCAGTAAAGAAAGGACGTCGATCGAGGCGGTGTGGGCAGTGTCCCGGCTGCCAGG
TGCCTGAGGACTGTGGTGTTTGTACTAATTGCTTAGATAAGCCCAAGTTTGGTGGTCGCAATATAAAGAAGCAGTGCTGCAAGATGAGAA
AATGTCAGAATCTACAATGGATGCCTTCCAAAGCCTACCTGCAGAAGCAAGCTAAAGCTGTGAAAAAGAAAGAGAAAAAGTCTAAGACCA
GTGAAAAGAAAGACAGCAAAGAGAGCAGTGTTGTGAAGAACGTGGTGGACTCTAGTCAGAAACCTACCCCATCAGCAAGAGAGGATCCTG
CCCCAAAGAAAAGCAGTAGTGAGCCTCCTCCACGAAAGCCCGTCGAGGAAAAGAGTGAAGAAGGGAATGTCTCGGCCCCTGGGCCTGAAT
CCAAACAGGCCACCACTCCAGCTTCCAGGAAGTCAAGCAAGCAGGTCTCCCAGCCAGCACTGGTCATCCCGCCTCAGCCACCTACTACAG
GACCGCCAAGAAAAGAAGTTCCCAAAACCACTCCTAGTGAGCCCAAGAAAAAGCAGCCTCCACCACCAGAATCAGGTCCAGAGCAGAGCA
AACAGAAAAAAGTGGCTCCCCGCCCAAGTATCCCTGTAAAACAAAAACCAAAAGAAAAGGAGATGACCTGGCTTCCACCACTTTCTGCTA
TTCAAGCACCTGGCAAAGTGGAACCAACCAAATTTCCATTTCCAAATAAGGACTCTCAGCTTGTATCCTCTGGACACAATAATCCAAAGA
AAGGTGATGCAGAGCCAGAGAGTCCAGACAGTGGCACATCGAATACATCAATGCTGGAAGATGACCTTAAGCTAAGCAGTGATGAAGAGG
AGAATGAACAGCAGGCAGCTCAGAGAACGGCTCTCCGCGCTCTCTCTGACAGCGCCGTGGTCCAGCAGCCCAACTGCAGAACCTCGGTGC
CTTCCAGCAAGGGCAGCAGCAGCAGCAGCAGCAGCGGCAGCAGCAGCTCCTCCAGCGACTCAGAGAGCAGCTCCGGATCTGACTCGGAGA
CCGAGAGCAGCTCCAGCGAGAGTGAGGGCAGCAAGCCCCCCCACTTCTCCAGCCCCGAGGCTGAACCGGCATCCTCTAACAAGTGGCAGC
TGGATAAATGGCTAAACAAAGTTAATCCCCACAAGCCTCCTATTCTGATCCAAAATGAAAGCCACGGGTCAGAGAGCAATCAGTACTACA
ACCCGGTGAAAGAGGACGTCCAGGACTGTGGGAAAGTCCCCGACGTTTGCCAGCCCAGCCTGAGAGAGAAGGAGATCAAGAGCACTTGCA
AGGAGGAGCAAAGGCCAAGGACAGCCAACAAGGCCCCTGGGAGTAAAGGCGTGAAGCAGAAGTCCCCGCCCGCGGCCGTGGCCGTGGCGG
TGAGCGCAGCCGCCCCGCCACCCGCAGTGCCCTGTGCGCCCGCGGAGAACGCGCCCGCGCCTGCCCGGAGGTCCGCGGGCAAGAAGCCCA
CCAGGCGCACCGAGAGGACCTCAGCCGGGGACGGCGCCAACTGCCACCGGCCCGAGGAGCCCGCGGCCGCGGACGCGCTGGGGACGAGCG
TGGTGGTCCCCCCGGAGCCCACCAAAACCAGGCCCTGTGGCAACAACAGAGCGAGCCACCGCAAGGAGCTGCGCTCCTCCGTGACCTGCG
AGAAGCGCCGCACGCGGGGGCTAAGCAGGATCGTCCCCAAATCCAAGGAGTTCATTGAGACAGAGTCGTCATCTTCATCCTCCTCCTCGG
ACTCCGACCTGGAGTCCGAGCAGGAGGAGTACCCTCTGTCCAAAGCACAGACCGTGGCTGCCTCTGCCTCCTCCGGGAATGATCAGAGGC
TGAAGGAGGCCGCTGCCAACGGGGGCAGTGGTCCTAGGGCCCCTGTAGGCTCCATCAACGCCAGGACCACCAGTGACATCGCCAAGGAGC
TGGAGGAGCAGTTCTACACACTGGTCCCCTTTGGCCGGAACGAACTTCTCTCCCCTCTAAAGGACAGTGATGAGATCAGGTCTCTCTGGG
TCAAAATCGACCTGACCCTCCTGTCCAGGATCCCAGAACACCTGCCCCAGGAGCCAGGGGTATTGAGCGCCCCTGCCACCAAGGACTCTG
AGAGCGCACCGCCCAGCCACACCTCGGACACACCTGCAGAAAAGGCTTTGCCAAAATCCAAGAGGAAACGCAAGTGTGACAACGAAGACG
ACTACAGGGAGATCAAGAAGTCCCAGGGAGAGAAAGACAGCTCTTCAAGACTGGCCACCTCCACCAGTAATACTTTGTCTGCAAACCACT
GCAACATGAACATCAACAGTGTGGCAATACCAATAAATAAAAATGAAAAAATGCTTCGGTCGCCCATCTCACCCCTCTCTGATGCATCTA
AACACAAATACACCAGCGAGGACTTAACTTCTTCCAGCCGACCTAATGGCAACAGTTTGTTTACTTCAGCCTCTTCCAGCAAAAAGCCTA
AGGCCGACAGCCAGCTGCAGCCTCACGGCGGAGACCTCACGAAAGCAGCTCACAACAATTCTGAAAACATTCCCCTCCACAAGTCACGGC
CGCAGACGAAGCCGTGGTCTCCAGGCTCCAACGGCCACAGGGACTGCAAGAGGCAGAAACTTGTCTTCGATGATATGCCTCGCAGTGCCG
ATTATTTTATGCAAGAAGCTAAACGAATGAAGCATAAAGCAGATGCAATGGTGGAAAAGTTTGGAAAGGCTTTGAACTATGCTGAAGCAG
CATTGTCGTTTATCGAGTGTGGAAATGCAATGGAACAAGGCCCCATGGAATCCAAATCTCCTTATACGATGTATTCAGAAACAGTAGAGC
TCATCAGGTATGCTATGAGACTAAAAACCCACTCAGGCCCCAATGCCACACCAGAAGACAAACAACTGGCTGCATTATGTTACCGATGCC
TGGCCCTCCTGTACTGGCGGATGTTTCGACTCAAAAGGGACCACGCTGTAAAGTATTCAAAAGCACTAATCGACTATTTCAAGAACTCAT
CTAAAGCCGCCCAAGCCCCATCTCCGTGGGGGGCCAGTGGAAAGAGCACTGGAACCCCATCCCCCATGTCTCCCAACCCCTCTCCCGCCA
GCTCCGTGGGGTCTCAGGGCAGCCTCTCCAACGCCAGCGCCCTGTCCCCGTCGACCATCGTCAGCATCCCACAGCGCATCCACCAGATGG
CGGCCAACCACGTCAGCATCACCAACAGCATCCTGCACAGCTACGACTACTGGGAGATGGCCGACAACCTGGCCAAGGAAAACCGAGAAT
TCTTCAACGACCTGGATCTGCTCATGGGGCCGGTCACCCTGCACAGCAGCATGGAGCACCTGGTCCAGTACTCCCAACAGGGCCTGCACT
GGCTGCGGAACAGCGCCCACCTGTCATAGGGACCTCACCCTGGGGCCAGAGTGGGCTCTGGTCTCCACAGATGGCTCAACGTTTTTGGAC
ACTGTGCTACTGAAACTCCCAGCCACAGCATTTATCAGACTGCGGTGAACATTTCCTCAGCATTGAACAATGATCTTTTGCAGGGCATGT
GTGTTTGTATGTGTGGGTATATAAGAAGCCGCCTGTGTATGTGTGTAAGATACACAGCTCTTCAGAACACACCTTCTTTGTCTAGTTTCC
ATAATCCCAGGCTAGACAAAGTGATCAGAGGTTTCTGACTAGAGGAAGTACACACACACACACACACACACACACACACCGTACACTCAC

>In-frame_ENST00000534358_ENST00000409579_AF422798_KMT2A_chr11_118353211_+_AFF3_chr2_100368765_length(amino acids)=2281AA_start in transcript=23_stop in transcript=6868
MAHSCRWRFPARPGTTGGGGGGGRRGLGGAPRQRVPALLLPPGPPVGGGGPGAPPSPPAVAAAAAAAGSSGAGVPGGAAAASAASSSSAS
SSSSSSSSASSGPALLRVGPGFDAALQVSAAIGTNLRRFRAVFGESGGGGGSGEDEQFLGFGSDEEVRVRSPTRSPSVKTSPRKPRGRPR
SGSDRNSAILSDPSVFSPLNKSETKSGDKIKKKDSKSIEKKRGRPPTFPGVKIKITHGKDISELPKGNKEDSLKKIKRTPSATFQQATKI
KKLRAGKLSPLKSKFKTGKLQIGRKGVQIVRRRGRPPSTERIKTPSGLLINSELEKPQKVRKDKEGTPPLTKEDKTVVRQSPRRIKPVRI
IPSSKRTDATIAKQLLQRAKKGAQKKIEKEAAQLQGRKVKTQVKNIRQFIMPVVSAISSRIIKTPRRFIEDEDYDPPIKIARLESTPNSR
FSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGS
RTTKKLSTLQSAPQQQTSSSPPPPLLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQ
YFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSN
RTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESA
EKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQ
SSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKILIKKGRGNLEKTNLDLGPTAPSLEKEKTLC
LSTPSSSTVKHSTSSIGSMLAQADKLPMTDKRVASLLKKAKAQLCKIEKSKSLKQTDQPKAQGQESDSSETSVRGPRIKHVCRRAAVALG
RKRAVFPDDMPTLSALPWEEREKILSSMGNDDKSSIAGSEDAEPLAPPIKPIKPVTRNKAPQEPPVKKGRRSRRCGQCPGCQVPEDCGVC
TNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKSSSE
PPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPR
PSIPVKQKPKEKEMTWLPPLSAIQAPGKVEPTKFPFPNKDSQLVSSGHNNPKKGDAEPESPDSGTSNTSMLEDDLKLSSDEEENEQQAAQ
RTALRALSDSAVVQQPNCRTSVPSSKGSSSSSSSGSSSSSSDSESSSGSDSETESSSSESEGSKPPHFSSPEAEPASSNKWQLDKWLNKV
NPHKPPILIQNESHGSESNQYYNPVKEDVQDCGKVPDVCQPSLREKEIKSTCKEEQRPRTANKAPGSKGVKQKSPPAAVAVAVSAAAPPP
AVPCAPAENAPAPARRSAGKKPTRRTERTSAGDGANCHRPEEPAAADALGTSVVVPPEPTKTRPCGNNRASHRKELRSSVTCEKRRTRGL
SRIVPKSKEFIETESSSSSSSSDSDLESEQEEYPLSKAQTVAASASSGNDQRLKEAAANGGSGPRAPVGSINARTTSDIAKELEEQFYTL
VPFGRNELLSPLKDSDEIRSLWVKIDLTLLSRIPEHLPQEPGVLSAPATKDSESAPPSHTSDTPAEKALPKSKRKRKCDNEDDYREIKKS
QGEKDSSSRLATSTSNTLSANHCNMNINSVAIPINKNEKMLRSPISPLSDASKHKYTSEDLTSSSRPNGNSLFTSASSSKKPKADSQLQP
HGGDLTKAAHNNSENIPLHKSRPQTKPWSPGSNGHRDCKRQKLVFDDMPRSADYFMQEAKRMKHKADAMVEKFGKALNYAEAALSFIECG
NAMEQGPMESKSPYTMYSETVELIRYAMRLKTHSGPNATPEDKQLAALCYRCLALLYWRMFRLKRDHAVKYSKALIDYFKNSSKAAQAPS
PWGASGKSTGTPSPMSPNPSPASSVGSQGSLSNASALSPSTIVSIPQRIHQMAANHVSITNSILHSYDYWEMADNLAKENREFFNDLDLL

--------------------------------------------------------------
>In-frame_ENST00000389506_ENST00000409236_AF422798_KMT2A_chr11_118353211_+_AFF3_chr2_100368765_length(transcript)=12459nt_BP=4086nt
ATGGCGCACAGCTGTCGGTGGCGCTTCCCCGCCCGACCCGGGACCACCGGGGGCGGCGGCGGCGGGGGGCGCCGGGGCCTAGGGGGCGCC
CCGCGGCAACGCGTCCCGGCCCTGCTGCTTCCCCCCGGGCCCCCGGTCGGCGGTGGCGGCCCCGGGGCGCCCCCCTCCCCCCCGGCTGTG
GCGGCCGCGGCGGCGGCGGCGGGAAGCAGCGGGGCTGGGGTTCCAGGGGGAGCGGCCGCCGCCTCAGCAGCCTCCTCGTCGTCCGCCTCG
TCTTCGTCTTCGTCATCGTCCTCAGCCTCTTCAGGGCCGGCCCTGCTCCGGGTGGGCCCGGGCTTCGACGCGGCGCTGCAGGTCTCGGCC
GCCATCGGCACCAACCTGCGCCGGTTCCGGGCCGTGTTTGGGGAGAGCGGCGGGGGAGGCGGCAGCGGAGAGGATGAGCAATTCTTAGGT
TTTGGCTCAGATGAAGAAGTCAGAGTGCGAAGTCCCACAAGGTCTCCTTCAGTTAAAACTAGTCCTCGAAAACCTCGTGGGAGACCTAGA
AGTGGCTCTGACCGAAATTCAGCTATCCTCTCAGATCCATCTGTGTTTTCCCCTCTAAATAAATCAGAGACCAAATCTGGAGATAAGATC
AAGAAGAAAGATTCTAAAAGTATAGAAAAGAAGAGAGGAAGACCTCCCACCTTCCCTGGAGTAAAAATCAAAATAACACATGGAAAGGAC
ATTTCAGAGTTACCAAAGGGAAACAAAGAAGATAGCCTGAAAAAAATTAAAAGGACACCTTCTGCTACGTTTCAGCAAGCCACAAAGATT
AAAAAATTAAGAGCAGGTAAACTCTCTCCTCTCAAGTCTAAGTTTAAGACAGGGAAGCTTCAAATAGGAAGGAAGGGGGTACAAATTGTA
CGACGGAGAGGAAGGCCTCCATCAACAGAAAGGATAAAGACCCCTTCGGGTCTCCTCATTAATTCTGAACTGGAAAAGCCCCAGAAAGTC
CGGAAAGACAAGGAAGGAACACCTCCACTTACAAAAGAAGATAAGACAGTTGTCAGACAAAGCCCTCGAAGGATTAAGCCAGTTAGGATT
ATTCCTTCTTCAAAAAGGACAGATGCAACCATTGCTAAGCAACTCTTACAGAGGGCAAAAAAGGGGGCTCAAAAGAAAATTGAAAAAGAA
GCAGCTCAGCTGCAGGGAAGAAAGGTGAAGACACAGGTCAAAAATATTCGACAGTTCATCATGCCTGTTGTCAGTGCTATCTCCTCGCGG
ATCATTAAGACCCCTCGGCGGTTTATAGAGGATGAGGATTATGACCCTCCAATTAAAATTGCCCGATTAGAGTCTACACCGAATAGTAGA
TTCAGTGCCCCGTCCTGTGGATCTTCTGAAAAATCAAGTGCAGCTTCTCAGCACTCCTCTCAAATGTCTTCAGACTCCTCTCGATCTAGT
AGCCCCAGTGTTGATACCTCCACAGACTCTCAGGCTTCTGAGGAGATTCAGGTACTTCCTGAGGAGCGGAGCGATACCCCTGAAGTTCAT
CCTCCACTGCCCATTTCCCAGTCCCCAGAAAATGAGAGTAATGATAGGAGAAGCAGAAGGTATTCAGTGTCGGAGAGAAGTTTTGGATCT
AGAACGACGAAAAAATTATCAACTCTACAAAGTGCCCCCCAGCAGCAGACCTCCTCGTCTCCACCTCCACCTCTGCTGACTCCACCGCCA
CCACTGCAGCCAGCCTCCAGTATCTCTGACCACACACCTTGGCTTATGCCTCCAACAATCCCCTTAGCATCACCATTTTTGCCTGCTTCC
ACTGCTCCTATGCAAGGGAAGCGAAAATCTATTTTGCGAGAACCGACATTTAGGTGGACTTCTTTAAAGCATTCTAGGTCAGAGCCACAA
TACTTTTCCTCAGCAAAGTATGCCAAAGAAGGTCTTATTCGCAAACCAATATTTGATAATTTCCGACCCCCTCCACTAACTCCCGAGGAC
GTTGGCTTTGCATCTGGTTTTTCTGCATCTGGTACCGCTGCTTCAGCCCGATTGTTTTCGCCACTCCATTCTGGAACAAGGTTTGATATG
CACAAAAGGAGCCCTCTTCTGAGAGCTCCAAGATTTACTCCAAGTGAGGCTCACTCTAGAATATTTGAGTCTGTAACCTTGCCTAGTAAT
CGAACTTCTGCTGGAACATCTTCTTCAGGAGTATCCAATAGAAAAAGGAAAAGAAAAGTGTTTAGTCCTATTCGATCTGAACCAAGATCT
CCTTCTCACTCCATGAGGACAAGAAGTGGAAGGCTTAGTAGTTCTGAGCTCTCACCTCTCACCCCCCCGTCTTCTGTCTCTTCCTCGTTA
AGCATTTCTGTTAGTCCTCTTGCCACTAGTGCCTTAAACCCAACTTTTACTTTTCCTTCTCATTCCCTGACTCAGTCTGGGGAATCTGCA
GAGAAAAATCAGAGACCAAGGAAGCAGACTAGTGCTCCGGCAGAGCCATTTTCATCAAGTAGTCCTACTCCTCTCTTCCCTTGGTTTACC
CCAGGCTCTCAGACTGAAAGAGGGAGAAATAAAGACAAGGCCCCCGAGGAGCTGTCCAAAGATCGAGATGCTGACAAGAGCGTGGAGAAG
GACAAGAGTAGAGAGAGAGACCGGGAGAGAGAAAAGGAGAATAAGCGGGAGTCAAGGAAAGAGAAAAGGAAAAAGGGATCAGAAATTCAG
AGTAGTTCTGCTTTGTATCCTGTGGGTAGGGTTTCCAAAGAGAAGGTTGTTGGTGAAGATGTTGCCACTTCATCTTCTGCCAAAAAAGCA
ACAGGGCGGAAGAAGTCTTCATCACATGATTCTGGGACTGATATTACTTCTGTGACTCTTGGGGATACAACAGCTGTCAAAACCAAAATA
CTTATAAAGAAAGGGAGAGGAAATCTGGAAAAAACCAACTTGGACCTCGGCCCAACTGCCCCATCCCTGGAGAAGGAGAAAACCCTCTGC
CTTTCCACTCCTTCATCTAGCACTGTTAAACATTCCACTTCCTCCATAGGCTCCATGTTGGCTCAGGCAGACAAGCTTCCAATGACTGAC
AAGAGGGTTGCCAGCCTCCTAAAAAAGGCCAAAGCTCAGCTCTGCAAGATTGAGAAGAGTAAGAGTCTTAAACAAACCGACCAGCCCAAA
GCACAGGGTCAAGAAAGTGACTCATCAGAGACCTCTGTGCGAGGACCCCGGATTAAACATGTCTGCAGAAGAGCAGCTGTTGCCCTTGGC
CGAAAACGAGCTGTGTTTCCTGATGACATGCCCACCCTGAGTGCCTTACCATGGGAAGAACGAGAAAAGATTTTGTCTTCCATGGGGAAT
GATGACAAGTCATCAATTGCTGGCTCAGAAGATGCTGAACCTCTTGCTCCACCCATCAAACCAATTAAACCTGTCACTAGAAACAAGGCA
CCCCAGGAACCTCCAGTAAAGAAAGGACGTCGATCGAGGCGGTGTGGGCAGTGTCCCGGCTGCCAGGTGCCTGAGGACTGTGGTGTTTGT
ACTAATTGCTTAGATAAGCCCAAGTTTGGTGGTCGCAATATAAAGAAGCAGTGCTGCAAGATGAGAAAATGTCAGAATCTACAATGGATG
CCTTCCAAAGCCTACCTGCAGAAGCAAGCTAAAGCTGTGAAAAAGAAAGAGAAAAAGTCTAAGACCAGTGAAAAGAAAGACAGCAAAGAG
AGCAGTGTTGTGAAGAACGTGGTGGACTCTAGTCAGAAACCTACCCCATCAGCAAGAGAGGATCCTGCCCCAAAGAAAAGCAGTAGTGAG
CCTCCTCCACGAAAGCCCGTCGAGGAAAAGAGTGAAGAAGGGAATGTCTCGGCCCCTGGGCCTGAATCCAAACAGGCCACCACTCCAGCT
TCCAGGAAGTCAAGCAAGCAGGTCTCCCAGCCAGCACTGGTCATCCCGCCTCAGCCACCTACTACAGGACCGCCAAGAAAAGAAGTTCCC
AAAACCACTCCTAGTGAGCCCAAGAAAAAGCAGCCTCCACCACCAGAATCAGGTCCAGAGCAGAGCAAACAGAAAAAAGTGGCTCCCCGC
CCAAGTATCCCTGTAAAACAAAAACCAAAAGAAAAGGAGATGACCTGGCTTCCACCACTTTCTGCTATTCAAGCACCTGGCAAAGTGGAA
CCAACCAAATTTCCATTTCCAAATAAGGACTCTCAGCTTGTATCCTCTGGACACAATAATCCAAAGAAAGGTGATGCAGAGCCAGAGAGT
CCAGACAGTGGCACATCGAATACATCAATGCTGGAAGATGACCTTAAGCTAAGCAGTGATGAAGAGGAGAATGAACAGCAGGCAGCTCAG
AGAACGGCTCTCCGCGCTCTCTCTGACAGCGCCGTGGTCCAGCAGCCCAACTGCAGAACCTCGGTGCCTTCCAGCAAGGGCAGCAGCAGC
AGCAGCAGCAGCGGCAGCAGCAGCTCCTCCAGCGACTCAGAGAGCAGCTCCGGATCTGACTCGGAGACCGAGAGCAGCTCCAGCGAGAGT
GAGGGCAGCAAGCCCCCCCACTTCTCCAGCCCCGAGGCTGAACCGGCATCCTCTAACAAGTGGCAGCTGGATAAATGGCTAAACAAAGTT
AATCCCCACAAGCCTCCTATTCTGATCCAAAATGAAAGCCACGGGTCAGAGAGCAATCAGTACTACAACCCGGTGAAAGAGGACGTCCAG
GACTGTGGGAAAGTCCCCGACGTTTGCCAGCCCAGCCTGAGAGAGAAGGAGATCAAGAGCACTTGCAAGGAGGAGCAAAGGCCAAGGACA
GCCAACAAGGCCCCTGGGAGTAAAGGCGTGAAGCAGAAGTCCCCGCCCGCGGCCGTGGCCGTGGCGGTGAGCGCAGCCGCCCCGCCACCC
GCAGTGCCCTGTGCGCCCGCGGAGAACGCGCCCGCGCCTGCCCGGAGGTCCGCGGGCAAGAAGCCCACCAGGCGCACCGAGAGGACCTCA
GCCGGGGACGGCGCCAACTGCCACCGGCCCGAGGAGCCCGCGGCCGCGGACGCGCTGGGGACGAGCGTGGTGGTCCCCCCGGAGCCCACC
AAAACCAGGCCCTGTGGCAACAACAGAGCGAGCCACCGCAAGGAGCTGCGCTCCTCCGTGACCTGCGAGAAGCGCCGCACGCGGGGGCTA
AGCAGGATCGTCCCCAAATCCAAGGAGTTCATTGAGACAGAGTCGTCATCTTCATCCTCCTCCTCGGACTCCGACCTGGAGTCCGAGCAG
GAGGAGTACCCTCTGTCCAAAGCACAGACCGTGGCTGCCTCTGCCTCCTCCGGGAATGATCAGAGGCTGAAGGAGGCCGCTGCCAACGGG
GGCAGTGGTCCTAGGGCCCCTGTAGGCTCCATCAACGCCAGGACCACCAGTGACATCGCCAAGGAGCTGGAGGAGCAGTTCTACACACTG
GTCCCCTTTGGCCGGAACGAACTTCTCTCCCCTCTAAAGGACAGTGATGAGATCAGGTCTCTCTGGGTCAAAATCGACCTGACCCTCCTG
TCCAGGATCCCAGAACACCTGCCCCAGGAGCCAGGGGTATTGAGCGCCCCTGCCACCAAGGACTCTGAGAGCGCACCGCCCAGCCACACC
TCGGACACACCTGCAGAAAAGGCTTTGCCAAAATCCAAGAGGAAACGCAAGTGTGACAACGAAGACGACTACAGGGAGATCAAGAAGTCC
CAGGGAGAGAAAGACAGCTCTTCAAGACTGGCCACCTCCACCAGTAATACTTTGTCTGCAAACCACTGCAACATGAACATCAACAGTGTG
GCAATACCAATAAATAAAAATGAAAAAATGCTTCGGTCGCCCATCTCACCCCTCTCTGATGCATCTAAACACAAATACACCAGCGAGGAC
TTAACTTCTTCCAGCCGACCTAATGGCAACAGTTTGTTTACTTCAGCCTCTTCCAGCAAAAAGCCTAAGGCCGACAGCCAGCTGCAGCCT
CACGGCGGAGACCTCACGAAAGCAGCTCACAACAATTCTGAAAACATTCCCCTCCACAAGTCACGGCCGCAGACGAAGCCGTGGTCTCCA
GGCTCCAACGGCCACAGGGACTGCAAGAGGCAGAAACTTGTCTTCGATGATATGCCTCGCAGTGCCGATTATTTTATGCAAGAAGCTAAA
CGAATGAAGCATAAAGCAGATGCAATGGTGGAAAAGTTTGGAAAGGCTTTGAACTATGCTGAAGCAGCATTGTCGTTTATCGAGTGTGGA
AATGCAATGGAACAAGGCCCCATGGAATCCAAATCTCCTTATACGATGTATTCAGAAACAGTAGAGCTCATCAGGTATGCTATGAGACTA
AAAACCCACTCAGGCCCCAATGCCACACCAGAAGACAAACAACTGGCTGCATTATGTTACCGATGCCTGGCCCTCCTGTACTGGCGGATG
TTTCGACTCAAAAGGGACCACGCTGTAAAGTATTCAAAAGCACTAATCGACTATTTCAAGAACTCATCTAAAGCCGCCCAAGCCCCATCT
CCGTGGGGGGCCAGTGGAAAGAGCACTGGAACCCCATCCCCCATGTCTCCCAACCCCTCTCCCGCCAGCTCCGTGGGGTCTCAGGGCAGC
CTCTCCAACGCCAGCGCCCTGTCCCCGTCGACCATCGTCAGCATCCCACAGCGCATCCACCAGATGGCGGCCAACCACGTCAGCATCACC
AACAGCATCCTGCACAGCTACGACTACTGGGAGATGGCCGACAACCTGGCCAAGGAAAACCGAGAATTCTTCAACGACCTGGATCTGCTC
ATGGGGCCGGTCACCCTGCACAGCAGCATGGAGCACCTGGTCCAGTACTCCCAACAGGGCCTGCACTGGCTGCGGAACAGCGCCCACCTG
TCATAGGGACCTCACCCTGGGGCCAGAGTGGGCTCTGGTCTCCACAGATGGCTCAACGTTTTTGGACACTGTGCTACTGAAACTCCCAGC
CACAGCATTTATCAGACTGCGGTGAACATTTCCTCAGCATTGAACAATGATCTTTTGCAGGGCATGTGTGTTTGTATGTGTGGGTATATA
AGAAGCCGCCTGTGTATGTGTGTAAGATACACAGCTCTTCAGAACACACCTTCTTTGTCTAGTTTCCATAATCCCAGGCTAGACAAAGTG
ATCAGAGGTTTCTGACTAGAGGAAGTACACACACACACACACACACACACACACACCGTACACTCACACACAATCACAGACACACACTTT
CTATTCCATTCCAGTGCTAAACCGTGACTTCTTAGAAAATTCAACCAAAATCTCATGGGTTAGTTAACCAGGTGCAATACAGCACACCAA
AAGCTTGACTGCCAGTGAAGATGGACCTGCTCTTATACTGTTGATTACTTTCAGTATTAATATACTATTCCCCAATTATTTTTTGATTGG
TATGTATTAATGGGTAATTGAATAATGAAAATAAGCCAGGTATTTTTGTGCCGGAAGTTTACTAGATTGCATGTTACCAAATACCCTGCT
CTTCCTCTAATTCCCTTCCCCCATCTGACTCTATTATCAACTAAATGCATTCCAGGCAAACAGATGGACACTCACAGCCCTTCCCAGCCC
CACCTCCAAGTAGTATGCAAATGGCACTGAGATTTAGCAAAAACGCGGCGTCTTTGAAAGTTAACAGACACTAAGGTAGCAGTGCCTGTG
TGTTGGAGCTCAGTTAGGAGTTGAAGTTTTCTGCACCTGTGATAACAAGCCCACCAGCCACATGCATTTCTTCTTCCTGCCACTGTGACT
CGGTGGCTGTAGAGCCACATGGCATTTGTCAGCCAATCTGTTTCAAGTCTTTTCTTTCCACCAATAGCTTTCTTACAGATTTTCTTGGCT
AAATGAGGCCATTACCTAGATTGTCCCTTCAGTAGGAGCCTGAATCCTTCGCTTACCAGGCTGAGAGCTATTTGCCATGATAATGCTGAT
TCTCTCACTCCTCATGCAGAATGTGCACCTGCAGCCCTTTGATGCGTTTTGATTTGGGGGCGATTTTTCAGGCTTTGATTAGCAGGCTGC
TTGCAATGCAGAAGATCACAGTTCCTTTCTGGGGCAGCAGCAACCAGAGCCTCTTCCTGTGTCCTGTGTGTCTGGTATGTTTACACCTTG
CTCTGAGTTTTTCTCTTGTTTTCTTTTTTTAATTAAGTTTACATTTTAGTTTCTTTGACATCTTGTTTACAGTTTTTGTCTGATGTTTTT
TCTTTTGTAGTGTCTTATGCCCTAGATTTAGTCATCTTGTTAAATATATTTGGATATGAAATCTTGACGAAAAGAAAATAACTCCTGAAA
AAGAGGGTCTATCTTGCCACACGTTAAAAACAAAAATAATGTCCTTGTGGCCTCTTACTTGATAAAGTTGCACCAGGACGGTCTGAGAAA
GGCAGGCGGTGTAATATGTGGTGCAATCCATTTTTTCAAGGTGATGACGGCACAAAATACTTAGACTAGATGCTGATCCATAAACATTCA
CTGATATTCTTACAGGTTGGTTTGCAGTGTTAACATTTTTGTTAGCCTGATCTGTAGGTGGGAAGTAAGATCATCATAATTCCTTAGCTC
TGAGCACTGATTCAAAATTGTATAAATGACTGAACAACTTAGATGATTTGAAATTAATTGAAAATAAGAAGGGCTTGTGGAATTTGCATT
TGGCTTTGGCCTTCAAGCATTTGGAAATATTAAGAGAATTTCCATTTTACATGTCTCCAACTGGGGTGCTTCTTACAACCCTTTCACTTT
TTTTTTGAGACGAGTTTCGCTCTGTTGCCCAGGCTGGAGTGCAGTGGCACGATCTCGGCTCACTGCATCCTCTGCCTCCTGGGTTCAAGT
GATTGTCCCGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGTGTGCACTACCATGCCCAGCTAATTTTTGTGTTTTTAGTAGAGACTGGG
TTTCACCATGTTGGCCAGGCTCGTCTCAAACTCCTGACCTCAGGTGATCTACCCGCCTCCACCTCCCAAAGTGTTGTGATTACAGGCGTG
AGCCACCACACCCAGCCCTTTCACTAATTTTTGGCAGAGTTCACAATCCCATCCTATGTCAGAAACTTGAACCTAACTTAAGAAATTTTG
AGTCATTTTTTTGGAGGACTGAGGCTTTGTTCTACCTACTCTTGAAGAATCCTGATGAAATATTCAAACACATAAAGGGATGGCCCTGGA
GGTCTATCCTGCATACCTGGAGAGCTTCTCTGGTCCTGCCCACCTTGAAAGTTGCAGACTTTGTTGTAACATCTATGTGATGAGCTTCCC
TGTGAAGCCCCATTTGACAGGTGGGCCAGCAGTGTTTTATCAGCACTCTGATGGCCCACATTTCCCAGGAAAACTTCTTGAAACTTACCG
TTGTGGGCAGTGGTCAGAGCGTGTAGTTCTTATGACTGTCTTGTTTCATCTGTGGAGCACGTGTGGAGCACGTTGGTACAGCAGTTTCTG
TGGGGTTTGGCATGGGTGATTTTGGTTAGTAACCATCCTCCAATTGTTGCTTGTGAAAGTCATTCATAACTTGTTCCTTTTACTTAGTTT
TGTTGTTACTGCTGTTGTTGTTGGTTTGGTTGGTTTTGAGACCGGGTCTGGCTCTGTAGCCCAAGCTGGAATGCGGTGGCGCGATCATGG
CTCCCTGCAGCCTCAAACTCCTGGGCTCAAGCAATCCTCCTGCCTCAGCCTCCCAAGCAGCTGGGAAGATAGGCACGTGCCACCACACCC
GGCTAATTTTTTCTTTATTTTTTTTGTAGAGATGGGGGTCTCACTATGTTGCCCAGGCTGGTCTCAAACTCCTGGGCTCAAGCGATCCTT
TGGCCTCGGCCTCCCAAAGTGCATGAGCCACCATGCCTGGCCTGTTTAGTTTTGTTTCAAGTTGAAATACCTTTCTTGTGTTTTCTAATT
AGAAAAGTAATATCTACTCATTGTAAAAACTCAAACAGTGCAGAAATGTAGAAAGTAGAAAGTGTAAGTCCCTGGTTGTCCCTTCTGCCT
GAGACAACCACTGCTCACAGTTTGATGTATATCCTTCCAGAGACTCTCAAATTTAAGCAAATAATTTTTATTACCATGTCTTTTTATTTG
AAGACGTACATTTGCCTCCAAAGTTCAACACAAGTTCAACTGACCATATCCTTCCATGACCTGAATAGATGCTATCCTTTATCACGATGT
TCAATTGCCTTTGAAAGAGAGTAGTCCAGGTATATTCCTGATCAAAATTTGGCATTTTTGATGATACTACTCTACACAGATCAGACTCAT
GTGCAGAATCGTGCCTGGAGAGAGAGGTTTGGTTAAGACAGAGATTTCTGGAAACATTCAAATTGCAAATGGAAACTTGAAACCCACAAT
CTAATGAGGAATGTACTGGAAAAATAATCTGAAGAGTTGACAAATTGTGTACTAGATTGAACACATGGAATGCAATGCAATGAGACTTTC
TGCACTAAAACTTATCCTCATATGTACAACAATGATGTGTGTATTATATAACAGTGATGTGTACATTTCTGACACCCCATACATAATATA
CACAGTTTGTATAAATGCATACATTTAAAAATATATATGTACAATACAGCTAACATAAAACTGTAGTACGCCTGAAGGATATTACTAGTG
CCTAATATTGAGTATGAGTCACTGCGTGTTCGCATCAACTTGGAAGTGCAGTAATTGTTATAAAATTAATCAGTGCAGCCAACATTATTT
ATGAATCACATCTTTGAAACTGTGCAGTAGCATATACATATATATTTTTAAATAACATTTTTCACAGTTTTCCAGAGTTACTGTTGAAAT
CTGCATCACCAAAAAAAAAAAAAAGCAAGATTTTTTTAACAATGTAGACACTCTTCAGACCCAGTAATCTGCGTGTGATTTCCTATTTGT
AGATTCCCAAGAGACTTTAGCAGTCACCAGCCTTAATGCATGTACAGGATATTATTGTGACTTAATTTATCTGCAGTTTTTAATCCATGT
GAAATTGGAATTTATAAACGGACTTGGATTAAACATGTCTGCCTTTCTAAGGTTGCAAATGTTACATTAAATGATTTATGTTGTAAATGA
GAGAAGTTGAGTTGTACGTAAAAGACATCCACCAATTTCTGTGAATATTTTTACACGGAAACTTGAGAATCAAAATACGTTCAAGTCAGT
TGTTCTGGCTCCCAGTTTATAATCTCGAAAAGCAATCTTTTTGTTTCATAAATGGCTTAAATGTAGCTCCCACAGATTATCAGTATGAAG
TCTGACATTTTTCATGGAAAAGAAGTATGTTTTTCTTCATTATAACTATAGTTTACTATTTGTCTTTGCTATTTCCTGATACATACACAT
ACGCACACACGCGCGCACATGCATGCACGTATGCACATGCACGCTCCCAGTGTCCCAGTGAAGGCTCAACAGGAAGCTTGAGAAGGTCAT
CTCAATGGCCACAGGGTTCCTGTTCAACCAGTAGCCCTGGGATGCCGCTTTGCTTGTCATTCTTTAGTGTCACAAGTTAGTTCCCTGACT
TGTGTGCAGTCAGGGAACTGCACACAACTGAAACCAACATGGTGGAATCATGTTTGCAATATTTGGTTGAGTAAAATAAGATAATTTTGA
ACTAAAGAAGACGGAGGCATTAGACCAGTGGCTTGACATGAAGCATCCCCTATGTGGGAGGGTAAGTTTGTTAACTTCATTTTTAGTCTT
ATCTCCAACCCTTTTCCTTATCCTCCTCCCCAAACTAAAGAAGCAGAAACAGCAACAAAAGCAAAACCATCCCTTCACCTGATCCAGCCC
ATGTCCTTAGATTCAAATATCCTTTGTCTTTTTCCCATTATACCATCTGACATAACTCACTCGTGTCTAGAGAGAAAAATGCAGAAAGGG
TTTGTTTGCAGATGGGCAGTTCAGTTGAGTCCTCATTAACCAGGCAGAGGGGTGCAGAAGAAGCCTGACTCAGGGTCACCATGGAGAACT
CCTCATCCCAGAGATGGGTGGGACAGGAACTTGGCTTTGCTTCACCAACCACTGAGCTTGATACTCTTTCAGAGGTGGTTTGTGCTAAGA
AACACCCAGCAGTCTTTCAAGAACGTTCTCTTCTGTAGCTTTGCCTGCTACACAGCTGAAGTCTGTCCCTATAAGAATTATATTTGTAAA
AAGTAATACATTTTCGAAGAAACCCGGATCAAGTGGAATCTTGAAAGTTTTTTTAATGAAAGGGGAAAAACAACCTGACCACATAAACTG
CACTTCCAACCATTTGGAACCAGAGTTTATGTCCTCATTTTCCCATTCTCAGAAGAGCACAGTTTTTCAATATTACAACTTCCTGGCAAA
TAGCACAAGAAATGTTCAGACTTGAGATTTGTGTTCCCTTTGTCCAGATTATTCTGTATATGTCACCAAAGGGGTTAACTTGTTTGCTTG

>In-frame_ENST00000389506_ENST00000409236_AF422798_KMT2A_chr11_118353211_+_AFF3_chr2_100368765_length(amino acids)=2281AA_start in transcript=0_stop in transcript=6845
MAHSCRWRFPARPGTTGGGGGGGRRGLGGAPRQRVPALLLPPGPPVGGGGPGAPPSPPAVAAAAAAAGSSGAGVPGGAAAASAASSSSAS
SSSSSSSSASSGPALLRVGPGFDAALQVSAAIGTNLRRFRAVFGESGGGGGSGEDEQFLGFGSDEEVRVRSPTRSPSVKTSPRKPRGRPR
SGSDRNSAILSDPSVFSPLNKSETKSGDKIKKKDSKSIEKKRGRPPTFPGVKIKITHGKDISELPKGNKEDSLKKIKRTPSATFQQATKI
KKLRAGKLSPLKSKFKTGKLQIGRKGVQIVRRRGRPPSTERIKTPSGLLINSELEKPQKVRKDKEGTPPLTKEDKTVVRQSPRRIKPVRI
IPSSKRTDATIAKQLLQRAKKGAQKKIEKEAAQLQGRKVKTQVKNIRQFIMPVVSAISSRIIKTPRRFIEDEDYDPPIKIARLESTPNSR
FSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGS
RTTKKLSTLQSAPQQQTSSSPPPPLLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQ
YFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSN
RTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESA
EKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQ
SSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKILIKKGRGNLEKTNLDLGPTAPSLEKEKTLC
LSTPSSSTVKHSTSSIGSMLAQADKLPMTDKRVASLLKKAKAQLCKIEKSKSLKQTDQPKAQGQESDSSETSVRGPRIKHVCRRAAVALG
RKRAVFPDDMPTLSALPWEEREKILSSMGNDDKSSIAGSEDAEPLAPPIKPIKPVTRNKAPQEPPVKKGRRSRRCGQCPGCQVPEDCGVC
TNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKSSSE
PPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPR
PSIPVKQKPKEKEMTWLPPLSAIQAPGKVEPTKFPFPNKDSQLVSSGHNNPKKGDAEPESPDSGTSNTSMLEDDLKLSSDEEENEQQAAQ
RTALRALSDSAVVQQPNCRTSVPSSKGSSSSSSSGSSSSSSDSESSSGSDSETESSSSESEGSKPPHFSSPEAEPASSNKWQLDKWLNKV
NPHKPPILIQNESHGSESNQYYNPVKEDVQDCGKVPDVCQPSLREKEIKSTCKEEQRPRTANKAPGSKGVKQKSPPAAVAVAVSAAAPPP
AVPCAPAENAPAPARRSAGKKPTRRTERTSAGDGANCHRPEEPAAADALGTSVVVPPEPTKTRPCGNNRASHRKELRSSVTCEKRRTRGL
SRIVPKSKEFIETESSSSSSSSDSDLESEQEEYPLSKAQTVAASASSGNDQRLKEAAANGGSGPRAPVGSINARTTSDIAKELEEQFYTL
VPFGRNELLSPLKDSDEIRSLWVKIDLTLLSRIPEHLPQEPGVLSAPATKDSESAPPSHTSDTPAEKALPKSKRKRKCDNEDDYREIKKS
QGEKDSSSRLATSTSNTLSANHCNMNINSVAIPINKNEKMLRSPISPLSDASKHKYTSEDLTSSSRPNGNSLFTSASSSKKPKADSQLQP
HGGDLTKAAHNNSENIPLHKSRPQTKPWSPGSNGHRDCKRQKLVFDDMPRSADYFMQEAKRMKHKADAMVEKFGKALNYAEAALSFIECG
NAMEQGPMESKSPYTMYSETVELIRYAMRLKTHSGPNATPEDKQLAALCYRCLALLYWRMFRLKRDHAVKYSKALIDYFKNSSKAAQAPS
PWGASGKSTGTPSPMSPNPSPASSVGSQGSLSNASALSPSTIVSIPQRIHQMAANHVSITNSILHSYDYWEMADNLAKENREFFNDLDLL

--------------------------------------------------------------
>In-frame_ENST00000389506_ENST00000356421_AF422798_KMT2A_chr11_118353211_+_AFF3_chr2_100368765_length(transcript)=11064nt_BP=4086nt
ATGGCGCACAGCTGTCGGTGGCGCTTCCCCGCCCGACCCGGGACCACCGGGGGCGGCGGCGGCGGGGGGCGCCGGGGCCTAGGGGGCGCC
CCGCGGCAACGCGTCCCGGCCCTGCTGCTTCCCCCCGGGCCCCCGGTCGGCGGTGGCGGCCCCGGGGCGCCCCCCTCCCCCCCGGCTGTG
GCGGCCGCGGCGGCGGCGGCGGGAAGCAGCGGGGCTGGGGTTCCAGGGGGAGCGGCCGCCGCCTCAGCAGCCTCCTCGTCGTCCGCCTCG
TCTTCGTCTTCGTCATCGTCCTCAGCCTCTTCAGGGCCGGCCCTGCTCCGGGTGGGCCCGGGCTTCGACGCGGCGCTGCAGGTCTCGGCC
GCCATCGGCACCAACCTGCGCCGGTTCCGGGCCGTGTTTGGGGAGAGCGGCGGGGGAGGCGGCAGCGGAGAGGATGAGCAATTCTTAGGT
TTTGGCTCAGATGAAGAAGTCAGAGTGCGAAGTCCCACAAGGTCTCCTTCAGTTAAAACTAGTCCTCGAAAACCTCGTGGGAGACCTAGA
AGTGGCTCTGACCGAAATTCAGCTATCCTCTCAGATCCATCTGTGTTTTCCCCTCTAAATAAATCAGAGACCAAATCTGGAGATAAGATC
AAGAAGAAAGATTCTAAAAGTATAGAAAAGAAGAGAGGAAGACCTCCCACCTTCCCTGGAGTAAAAATCAAAATAACACATGGAAAGGAC
ATTTCAGAGTTACCAAAGGGAAACAAAGAAGATAGCCTGAAAAAAATTAAAAGGACACCTTCTGCTACGTTTCAGCAAGCCACAAAGATT
AAAAAATTAAGAGCAGGTAAACTCTCTCCTCTCAAGTCTAAGTTTAAGACAGGGAAGCTTCAAATAGGAAGGAAGGGGGTACAAATTGTA
CGACGGAGAGGAAGGCCTCCATCAACAGAAAGGATAAAGACCCCTTCGGGTCTCCTCATTAATTCTGAACTGGAAAAGCCCCAGAAAGTC
CGGAAAGACAAGGAAGGAACACCTCCACTTACAAAAGAAGATAAGACAGTTGTCAGACAAAGCCCTCGAAGGATTAAGCCAGTTAGGATT
ATTCCTTCTTCAAAAAGGACAGATGCAACCATTGCTAAGCAACTCTTACAGAGGGCAAAAAAGGGGGCTCAAAAGAAAATTGAAAAAGAA
GCAGCTCAGCTGCAGGGAAGAAAGGTGAAGACACAGGTCAAAAATATTCGACAGTTCATCATGCCTGTTGTCAGTGCTATCTCCTCGCGG
ATCATTAAGACCCCTCGGCGGTTTATAGAGGATGAGGATTATGACCCTCCAATTAAAATTGCCCGATTAGAGTCTACACCGAATAGTAGA
TTCAGTGCCCCGTCCTGTGGATCTTCTGAAAAATCAAGTGCAGCTTCTCAGCACTCCTCTCAAATGTCTTCAGACTCCTCTCGATCTAGT
AGCCCCAGTGTTGATACCTCCACAGACTCTCAGGCTTCTGAGGAGATTCAGGTACTTCCTGAGGAGCGGAGCGATACCCCTGAAGTTCAT
CCTCCACTGCCCATTTCCCAGTCCCCAGAAAATGAGAGTAATGATAGGAGAAGCAGAAGGTATTCAGTGTCGGAGAGAAGTTTTGGATCT
AGAACGACGAAAAAATTATCAACTCTACAAAGTGCCCCCCAGCAGCAGACCTCCTCGTCTCCACCTCCACCTCTGCTGACTCCACCGCCA
CCACTGCAGCCAGCCTCCAGTATCTCTGACCACACACCTTGGCTTATGCCTCCAACAATCCCCTTAGCATCACCATTTTTGCCTGCTTCC
ACTGCTCCTATGCAAGGGAAGCGAAAATCTATTTTGCGAGAACCGACATTTAGGTGGACTTCTTTAAAGCATTCTAGGTCAGAGCCACAA
TACTTTTCCTCAGCAAAGTATGCCAAAGAAGGTCTTATTCGCAAACCAATATTTGATAATTTCCGACCCCCTCCACTAACTCCCGAGGAC
GTTGGCTTTGCATCTGGTTTTTCTGCATCTGGTACCGCTGCTTCAGCCCGATTGTTTTCGCCACTCCATTCTGGAACAAGGTTTGATATG
CACAAAAGGAGCCCTCTTCTGAGAGCTCCAAGATTTACTCCAAGTGAGGCTCACTCTAGAATATTTGAGTCTGTAACCTTGCCTAGTAAT
CGAACTTCTGCTGGAACATCTTCTTCAGGAGTATCCAATAGAAAAAGGAAAAGAAAAGTGTTTAGTCCTATTCGATCTGAACCAAGATCT
CCTTCTCACTCCATGAGGACAAGAAGTGGAAGGCTTAGTAGTTCTGAGCTCTCACCTCTCACCCCCCCGTCTTCTGTCTCTTCCTCGTTA
AGCATTTCTGTTAGTCCTCTTGCCACTAGTGCCTTAAACCCAACTTTTACTTTTCCTTCTCATTCCCTGACTCAGTCTGGGGAATCTGCA
GAGAAAAATCAGAGACCAAGGAAGCAGACTAGTGCTCCGGCAGAGCCATTTTCATCAAGTAGTCCTACTCCTCTCTTCCCTTGGTTTACC
CCAGGCTCTCAGACTGAAAGAGGGAGAAATAAAGACAAGGCCCCCGAGGAGCTGTCCAAAGATCGAGATGCTGACAAGAGCGTGGAGAAG
GACAAGAGTAGAGAGAGAGACCGGGAGAGAGAAAAGGAGAATAAGCGGGAGTCAAGGAAAGAGAAAAGGAAAAAGGGATCAGAAATTCAG
AGTAGTTCTGCTTTGTATCCTGTGGGTAGGGTTTCCAAAGAGAAGGTTGTTGGTGAAGATGTTGCCACTTCATCTTCTGCCAAAAAAGCA
ACAGGGCGGAAGAAGTCTTCATCACATGATTCTGGGACTGATATTACTTCTGTGACTCTTGGGGATACAACAGCTGTCAAAACCAAAATA
CTTATAAAGAAAGGGAGAGGAAATCTGGAAAAAACCAACTTGGACCTCGGCCCAACTGCCCCATCCCTGGAGAAGGAGAAAACCCTCTGC
CTTTCCACTCCTTCATCTAGCACTGTTAAACATTCCACTTCCTCCATAGGCTCCATGTTGGCTCAGGCAGACAAGCTTCCAATGACTGAC
AAGAGGGTTGCCAGCCTCCTAAAAAAGGCCAAAGCTCAGCTCTGCAAGATTGAGAAGAGTAAGAGTCTTAAACAAACCGACCAGCCCAAA
GCACAGGGTCAAGAAAGTGACTCATCAGAGACCTCTGTGCGAGGACCCCGGATTAAACATGTCTGCAGAAGAGCAGCTGTTGCCCTTGGC
CGAAAACGAGCTGTGTTTCCTGATGACATGCCCACCCTGAGTGCCTTACCATGGGAAGAACGAGAAAAGATTTTGTCTTCCATGGGGAAT
GATGACAAGTCATCAATTGCTGGCTCAGAAGATGCTGAACCTCTTGCTCCACCCATCAAACCAATTAAACCTGTCACTAGAAACAAGGCA
CCCCAGGAACCTCCAGTAAAGAAAGGACGTCGATCGAGGCGGTGTGGGCAGTGTCCCGGCTGCCAGGTGCCTGAGGACTGTGGTGTTTGT
ACTAATTGCTTAGATAAGCCCAAGTTTGGTGGTCGCAATATAAAGAAGCAGTGCTGCAAGATGAGAAAATGTCAGAATCTACAATGGATG
CCTTCCAAAGCCTACCTGCAGAAGCAAGCTAAAGCTGTGAAAAAGAAAGAGAAAAAGTCTAAGACCAGTGAAAAGAAAGACAGCAAAGAG
AGCAGTGTTGTGAAGAACGTGGTGGACTCTAGTCAGAAACCTACCCCATCAGCAAGAGAGGATCCTGCCCCAAAGAAAAGCAGTAGTGAG
CCTCCTCCACGAAAGCCCGTCGAGGAAAAGAGTGAAGAAGGGAATGTCTCGGCCCCTGGGCCTGAATCCAAACAGGCCACCACTCCAGCT
TCCAGGAAGTCAAGCAAGCAGGTCTCCCAGCCAGCACTGGTCATCCCGCCTCAGCCACCTACTACAGGACCGCCAAGAAAAGAAGTTCCC
AAAACCACTCCTAGTGAGCCCAAGAAAAAGCAGCCTCCACCACCAGAATCAGGTCCAGAGCAGAGCAAACAGAAAAAAGTGGCTCCCCGC
CCAAGTATCCCTGTAAAACAAAAACCAAAAGAAAAGGAGATGACCTGGCTTCCACCACTTTCTGCTATTCAAGCACCTGGCAAAGTGGAA
CCAACCAAATTTCCATTTCCAAATAAGGACTCTCAGCTTGTATCCTCTGGACACAATAATCCAAAGAAAGGTGATGCAGAGCCAGAGAGT
CCAGACAGTGGCACATCGAATACATCAATGCTGGAAGATGACCTTAAGCTAAGCAGTGATGAAGAGGAGAATGAACAGCAGGCAGCTCAG
AGAACGGCTCTCCGCGCTCTCTCTGACAGCGCCGTGGTCCAGCAGCCCAACTGCAGAACCTCGGTGCCTTCCAGCAAGGGCAGCAGCAGC
AGCAGCAGCAGCGGCAGCAGCAGCTCCTCCAGCGACTCAGAGAGCAGCTCCGGATCTGACTCGGAGACCGAGAGCAGCTCCAGCGAGAGT
GAGGGCAGCAAGCCCCCCCACTTCTCCAGCCCCGAGGCTGAACCGGCATCCTCTAACAAGTGGCAGCTGGATAAATGGCTAAACAAAGTT
AATCCCCACAAGCCTCCTATTCTGATCCAAAATGAAAGCCACGGGTCAGAGAGCAATCAGTACTACAACCCGGTGAAAGAGGACGTCCAG
GACTGTGGGAAAGTCCCCGACGTTTGCCAGCCCAGCCTGAGAGAGAAGGAGATCAAGAGCACTTGCAAGGAGGAGCAAAGGCCAAGGACA
GCCAACAAGGCCCCTGGGAGTAAAGGCGTGAAGCAGAAGTCCCCGCCCGCGGCCGTGGCCGTGGCGGTGAGCGCAGCCGCCCCGCCACCC
GCAGTGCCCTGTGCGCCCGCGGAGAACGCGCCCGCGCCTGCCCGGAGGTCCGCGGGCAAGAAGCCCACCAGGCGCACCGAGAGGACCTCA
GCCGGGGACGGCGCCAACTGCCACCGGCCCGAGGAGCCCGCGGCCGCGGACGCGCTGGGGACGAGCGTGGTGGTCCCCCCGGAGCCCACC
AAAACCAGGCCCTGTGGCAACAACAGAGCGAGCCACCGCAAGGAGCTGCGCTCCTCCGTGACCTGCGAGAAGCGCCGCACGCGGGGGCTA
AGCAGGATCGTCCCCAAATCCAAGGAGTTCATTGAGACAGAGTCGTCATCTTCATCCTCCTCCTCGGACTCCGACCTGGAGTCCGAGCAG
GAGGAGTACCCTCTGTCCAAAGCACAGACCGTGGCTGCCTCTGCCTCCTCCGGGAATGATCAGAGGCTGAAGGAGGCCGCTGCCAACGGG
GGCAGTGGTCCTAGGGCCCCTGTAGGCTCCATCAACGCCAGGACCACCAGTGACATCGCCAAGGAGCTGGAGGAGCAGTTCTACACACTG
GTCCCCTTTGGCCGGAACGAACTTCTCTCCCCTCTAAAGGACAGTGATGAGATCAGGTCTCTCTGGGTCAAAATCGACCTGACCCTCCTG
TCCAGGATCCCAGAACACCTGCCCCAGGAGCCAGGGGTATTGAGCGCCCCTGCCACCAAGGACTCTGAGAGCGCACCGCCCAGCCACACC
TCGGACACACCTGCAGAAAAGGCTTTGCCAAAATCCAAGAGGAAACGCAAGTGTGACAACGAAGACGACTACAGGGAGATCAAGAAGTCC
CAGGGAGAGAAAGACAGCTCTTCAAGACTGGCCACCTCCACCAGTAATACTTTGTCTGCAAACCACTGCAACATGAACATCAACAGTGTG
GCAATACCAATAAATAAAAATGAAAAAATGCTTCGGTCGCCCATCTCACCCCTCTCTGATGCATCTAAACACAAATACACCAGCGAGGAC
TTAACTTCTTCCAGCCGACCTAATGGCAACAGTTTGTTTACTTCAGCCTCTTCCAGCAAAAAGCCTAAGGCCGACAGCCAGCTGCAGCCT
CACGGCGGAGACCTCACGAAAGCAGCTCACAACAATTCTGAAAACATTCCCCTCCACAAGTCACGGCCGCAGACGAAGCCGTGGTCTCCA
GGCTCCAACGGCCACAGGGACTGCAAGAGGCAGAAACTTGTCTTCGATGATATGCCTCGCAGTGCCGATTATTTTATGCAAGAAGCTAAA
CGAATGAAGCATAAAGCAGATGCAATGGTGGAAAAGTTTGGAAAGGCTTTGAACTATGCTGAAGCAGCATTGTCGTTTATCGAGTGTGGA
AATGCAATGGAACAAGGCCCCATGGAATCCAAATCTCCTTATACGATGTATTCAGAAACAGTAGAGCTCATCAGGTATGCTATGAGACTA
AAAACCCACTCAGGCCCCAATGCCACACCAGAAGACAAACAACTGGCTGCATTATGTTACCGATGCCTGGCCCTCCTGTACTGGCGGATG
TTTCGACTCAAAAGGGACCACGCTGTAAAGTATTCAAAAGCACTAATCGACTATTTCAAGAACTCATCTAAAGCCGCCCAAGCCCCATCT
CCGTGGGGGGCCAGTGGAAAGAGCACTGGAACCCCATCCCCCATGTCTCCCAACCCCTCTCCCGCCAGCTCCGTGGGGTCTCAGGGCAGC
CTCTCCAACGCCAGCGCCCTGTCCCCGTCGACCATCGTCAGCATCCCACAGCGCATCCACCAGATGGCGGCCAACCACGTCAGCATCACC
AACAGCATCCTGCACAGCTACGACTACTGGGAGATGGCCGACAACCTGGCCAAGGAAAACCGAGAATTCTTCAACGACCTGGATCTGCTC
ATGGGGCCGGTCACCCTGCACAGCAGCATGGAGCACCTGGTCCAGTACTCCCAACAGGGCCTGCACTGGCTGCGGAACAGCGCCCACCTG
TCATAGGGACCTCACCCTGGGGCCAGAGTGGGCTCTGGTCTCCACAGATGGCTCAACGTTTTTGGACACTGTGCTACTGAAACTCCCAGC
CACAGCATTTATCAGACTGCGGTGAACATTTCCTCAGCATTGAACAATGATCTTTTGCAGGGCATGTGTGTTTGTATGTGTGGGTATATA
AGAAGCCGCCTGTGTATGTGTGTAAGATACACAGCTCTTCAGAACACACCTTCTTTGTCTAGTTTCCATAATCCCAGGCTAGACAAAGTG
ATCAGAGGTTTCTGACTAGAGGAAGTACACACACACACACACACACACACACACACCGTACACTCACACACAATCACAGACACACACTTT
CTATTCCATTCCAGTGCTAAACCGTGACTTCTTAGAAAATTCAACCAAAATCTCATGGGTTAGTTAACCAGGTGCAATACAGCACACCAA
AAGCTTGACTGCCAGTGAAGATGGACCTGCTCTTATACTGTTGATTACTTTCAGTATTAATATACTATTCCCCAATTATTTTTTGATTGG
TATGTATTAATGGGTAATTGAATAATGAAAATAAGCCAGGTATTTTTGTGCCGGAAGTTTACTAGATTGCATGTTACCAAATACCCTGCT
CTTCCTCTAATTCCCTTCCCCCATCTGACTCTATTATCAACTAAATGCATTCCAGGCAAACAGATGGACACTCACAGCCCTTCCCAGCCC
CACCTCCAAGTAGTATGCAAATGGCACTGAGATTTAGCAAAAACGCGGCGTCTTTGAAAGTTAACAGACACTAAGGTAGCAGTGCCTGTG
TGTTGGAGCTCAGTTAGGAGTTGAAGTTTTCTGCACCTGTGATAACAAGCCCACCAGCCACATGCATTTCTTCTTCCTGCCACTGTGACT
CGGTGGCTGTAGAGCCACATGGCATTTGTCAGCCAATCTGTTTCAAGTCTTTTCTTTCCACCAATAGCTTTCTTACAGATTTTCTTGGCT
AAATGAGGCCATTACCTAGATTGTCCCTTCAGTAGGAGCCTGAATCCTTCGCTTACCAGGCTGAGAGCTATTTGCCATGATAATGCTGAT
TCTCTCACTCCTCATGCAGAATGTGCACCTGCAGCCCTTTGATGCGTTTTGATTTGGGGGCGATTTTTCAGGCTTTGATTAGCAGGCTGC
TTGCAATGCAGAAGATCACAGTTCCTTTCTGGGGCAGCAGCAACCAGAGCCTCTTCCTGTGTCCTGTGTGTCTGGTATGTTTACACCTTG
CTCTGAGTTTTTCTCTTGTTTTCTTTTTTTAATTAAGTTTACATTTTAGTTTCTTTGACATCTTGTTTACAGTTTTTGTCTGATGTTTTT
TCTTTTGTAGTGTCTTATGCCCTAGATTTAGTCATCTTGTTAAATATATTTGGATATGAAATCTTGACGAAAAGAAAATAACTCCTGAAA
AAGAGGGTCTATCTTGCCACACGTTAAAAACAAAAATAATGTCCTTGTGGCCTCTTACTTGATAAAGTTGCACCAGGACGGTCTGAGAAA
GGCAGGCGGTGTAATATGTGGTGCAATCCATTTTTTCAAGGTGATGACGGCACAAAATACTTAGACTAGATGCTGATCCATAAACATTCA
CTGATATTCTTACAGGTTGGTTTGCAGTGTTAACATTTTTGTTAGCCTGATCTGTAGGTGGGAAGTAAGATCATCATAATTCCTTAGCTC
TGAGCACTGATTCAAAATTGTATAAATGACTGAACAACTTAGATGATTTGAAATTAATTGAAAATAAGAAGGGCTTGTGGAATTTGCATT
TGGCTTTGGCCTTCAAGCATTTGGAAATATTAAGAGAATTTCCATTTTACATGTCTCCAACTGGGGTGCTTCTTACAACCCTTTCACTTT
TTTTTTGAGACGAGTTTCGCTCTGTTGCCCAGGCTGGAGTGCAGTGGCACGATCTCGGCTCACTGCATCCTCTGCCTCCTGGGTTCAAGT
GATTGTCCCGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGTGTGCACTACCATGCCCAGCTAATTTTTGTGTTTTTAGTAGAGACTGGG
TTTCACCATGTTGGCCAGGCTCGTCTCAAACTCCTGACCTCAGGTGATCTACCCGCCTCCACCTCCCAAAGTGTTGTGATTACAGGCGTG
AGCCACCACACCCAGCCCTTTCACTAATTTTTGGCAGAGTTCACAATCCCATCCTATGTCAGAAACTTGAACCTAACTTAAGAAATTTTG
AGTCATTTTTTTGGAGGACTGAGGCTTTGTTCTACCTACTCTTGAAGAATCCTGATGAAATATTCAAACACATAAAGGGATGGCCCTGGA
GGTCTATCCTGCATACCTGGAGAGCTTCTCTGGTCCTGCCCACCTTGAAAGTTGCAGACTTTGTTGTAACATCTATGTGATGAGCTTCCC
TGTGAAGCCCCATTTGACAGGTGGGCCAGCAGTGTTTTATCAGCACTCTGATGGCCCACATTTCCCAGGAAAACTTCTTGAAACTTACCG
TTGTGGGCAGTGGTCAGAGCGTGTAGTTCTTATGACTGTCTTGTTTCATCTGTGGAGCACGTGTGGAGCACGTTGGTACAGCAGTTTCTG
TGGGGTTTGGCATGGGTGATTTTGGTTAGTAACCATCCTCCAATTGTTGCTTGTGAAAGTCATTCATAACTTGTTCCTTTTACTTAGTTT
TGTTGTTACTGCTGTTGTTGTTGGTTTGGTTGGTTTTGAGACCGGGTCTGGCTCTGTAGCCCAAGCTGGAATGCGGTGGCGCGATCATGG
CTCCCTGCAGCCTCAAACTCCTGGGCTCAAGCAATCCTCCTGCCTCAGCCTCCCAAGCAGCTGGGAAGATAGGCACGTGCCACCACACCC
GGCTAATTTTTTCTTTATTTTTTTTGTAGAGATGGGGGTCTCACTATGTTGCCCAGGCTGGTCTCAAACTCCTGGGCTCAAGCGATCCTT
TGGCCTCGGCCTCCCAAAGTGCATGAGCCACCATGCCTGGCCTGTTTAGTTTTGTTTCAAGTTGAAATACCTTTCTTGTGTTTTCTAATT
AGAAAAGTAATATCTACTCATTGTAAAAACTCAAACAGTGCAGAAATGTAGAAAGTAGAAAGTGTAAGTCCCTGGTTGTCCCTTCTGCCT
GAGACAACCACTGCTCACAGTTTGATGTATATCCTTCCAGAGACTCTCAAATTTAAGCAAATAATTTTTATTACCATGTCTTTTTATTTG
AAGACGTACATTTGCCTCCAAAGTTCAACACAAGTTCAACTGACCATATCCTTCCATGACCTGAATAGATGCTATCCTTTATCACGATGT
TCAATTGCCTTTGAAAGAGAGTAGTCCAGGTATATTCCTGATCAAAATTTGGCATTTTTGATGATACTACTCTACACAGATCAGACTCAT
GTGCAGAATCGTGCCTGGAGAGAGAGGTTTGGTTAAGACAGAGATTTCTGGAAACATTCAAATTGCAAATGGAAACTTGAAACCCACAAT
CTAATGAGGAATGTACTGGAAAAATAATCTGAAGAGTTGACAAATTGTGTACTAGATTGAACACATGGAATGCAATGCAATGAGACTTTC
TGCACTAAAACTTATCCTCATATGTACAACAATGATGTGTGTATTATATAACAGTGATGTGTACATTTCTGACACCCCATACATAATATA
CACAGTTTGTATAAATGCATACATTTAAAAATATATATGTACAATACAGCTAACATAAAACTGTAGTACGCCTGAAGGATATTACTAGTG
CCTAATATTGAGTATGAGTCACTGCGTGTTCGCATCAACTTGGAAGTGCAGTAATTGTTATAAAATTAATCAGTGCAGCCAACATTATTT
ATGAATCACATCTTTGAAACTGTGCAGTAGCATATACATATATATTTTTAAATAACATTTTTCACAGTTTTCCAGAGTTACTGTTGAAAT
CTGCATCACCAAAAAAAAAAAAAAGCAAGATTTTTTTAACAATGTAGACACTCTTCAGACCCAGTAATCTGCGTGTGATTTCCTATTTGT
AGATTCCCAAGAGACTTTAGCAGTCACCAGCCTTAATGCATGTACAGGATATTATTGTGACTTAATTTATCTGCAGTTTTTAATCCATGT

>In-frame_ENST00000389506_ENST00000356421_AF422798_KMT2A_chr11_118353211_+_AFF3_chr2_100368765_length(amino acids)=2281AA_start in transcript=0_stop in transcript=6845
MAHSCRWRFPARPGTTGGGGGGGRRGLGGAPRQRVPALLLPPGPPVGGGGPGAPPSPPAVAAAAAAAGSSGAGVPGGAAAASAASSSSAS
SSSSSSSSASSGPALLRVGPGFDAALQVSAAIGTNLRRFRAVFGESGGGGGSGEDEQFLGFGSDEEVRVRSPTRSPSVKTSPRKPRGRPR
SGSDRNSAILSDPSVFSPLNKSETKSGDKIKKKDSKSIEKKRGRPPTFPGVKIKITHGKDISELPKGNKEDSLKKIKRTPSATFQQATKI
KKLRAGKLSPLKSKFKTGKLQIGRKGVQIVRRRGRPPSTERIKTPSGLLINSELEKPQKVRKDKEGTPPLTKEDKTVVRQSPRRIKPVRI
IPSSKRTDATIAKQLLQRAKKGAQKKIEKEAAQLQGRKVKTQVKNIRQFIMPVVSAISSRIIKTPRRFIEDEDYDPPIKIARLESTPNSR
FSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGS
RTTKKLSTLQSAPQQQTSSSPPPPLLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQ
YFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSN
RTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESA
EKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQ
SSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKILIKKGRGNLEKTNLDLGPTAPSLEKEKTLC
LSTPSSSTVKHSTSSIGSMLAQADKLPMTDKRVASLLKKAKAQLCKIEKSKSLKQTDQPKAQGQESDSSETSVRGPRIKHVCRRAAVALG
RKRAVFPDDMPTLSALPWEEREKILSSMGNDDKSSIAGSEDAEPLAPPIKPIKPVTRNKAPQEPPVKKGRRSRRCGQCPGCQVPEDCGVC
TNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKSSSE
PPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPR
PSIPVKQKPKEKEMTWLPPLSAIQAPGKVEPTKFPFPNKDSQLVSSGHNNPKKGDAEPESPDSGTSNTSMLEDDLKLSSDEEENEQQAAQ
RTALRALSDSAVVQQPNCRTSVPSSKGSSSSSSSGSSSSSSDSESSSGSDSETESSSSESEGSKPPHFSSPEAEPASSNKWQLDKWLNKV
NPHKPPILIQNESHGSESNQYYNPVKEDVQDCGKVPDVCQPSLREKEIKSTCKEEQRPRTANKAPGSKGVKQKSPPAAVAVAVSAAAPPP
AVPCAPAENAPAPARRSAGKKPTRRTERTSAGDGANCHRPEEPAAADALGTSVVVPPEPTKTRPCGNNRASHRKELRSSVTCEKRRTRGL
SRIVPKSKEFIETESSSSSSSSDSDLESEQEEYPLSKAQTVAASASSGNDQRLKEAAANGGSGPRAPVGSINARTTSDIAKELEEQFYTL
VPFGRNELLSPLKDSDEIRSLWVKIDLTLLSRIPEHLPQEPGVLSAPATKDSESAPPSHTSDTPAEKALPKSKRKRKCDNEDDYREIKKS
QGEKDSSSRLATSTSNTLSANHCNMNINSVAIPINKNEKMLRSPISPLSDASKHKYTSEDLTSSSRPNGNSLFTSASSSKKPKADSQLQP
HGGDLTKAAHNNSENIPLHKSRPQTKPWSPGSNGHRDCKRQKLVFDDMPRSADYFMQEAKRMKHKADAMVEKFGKALNYAEAALSFIECG
NAMEQGPMESKSPYTMYSETVELIRYAMRLKTHSGPNATPEDKQLAALCYRCLALLYWRMFRLKRDHAVKYSKALIDYFKNSSKAAQAPS
PWGASGKSTGTPSPMSPNPSPASSVGSQGSLSNASALSPSTIVSIPQRIHQMAANHVSITNSILHSYDYWEMADNLAKENREFFNDLDLL

--------------------------------------------------------------
>In-frame_ENST00000389506_ENST00000317233_AF422798_KMT2A_chr11_118353211_+_AFF3_chr2_100368765_length(transcript)=11064nt_BP=4086nt
ATGGCGCACAGCTGTCGGTGGCGCTTCCCCGCCCGACCCGGGACCACCGGGGGCGGCGGCGGCGGGGGGCGCCGGGGCCTAGGGGGCGCC
CCGCGGCAACGCGTCCCGGCCCTGCTGCTTCCCCCCGGGCCCCCGGTCGGCGGTGGCGGCCCCGGGGCGCCCCCCTCCCCCCCGGCTGTG
GCGGCCGCGGCGGCGGCGGCGGGAAGCAGCGGGGCTGGGGTTCCAGGGGGAGCGGCCGCCGCCTCAGCAGCCTCCTCGTCGTCCGCCTCG
TCTTCGTCTTCGTCATCGTCCTCAGCCTCTTCAGGGCCGGCCCTGCTCCGGGTGGGCCCGGGCTTCGACGCGGCGCTGCAGGTCTCGGCC
GCCATCGGCACCAACCTGCGCCGGTTCCGGGCCGTGTTTGGGGAGAGCGGCGGGGGAGGCGGCAGCGGAGAGGATGAGCAATTCTTAGGT
TTTGGCTCAGATGAAGAAGTCAGAGTGCGAAGTCCCACAAGGTCTCCTTCAGTTAAAACTAGTCCTCGAAAACCTCGTGGGAGACCTAGA
AGTGGCTCTGACCGAAATTCAGCTATCCTCTCAGATCCATCTGTGTTTTCCCCTCTAAATAAATCAGAGACCAAATCTGGAGATAAGATC
AAGAAGAAAGATTCTAAAAGTATAGAAAAGAAGAGAGGAAGACCTCCCACCTTCCCTGGAGTAAAAATCAAAATAACACATGGAAAGGAC
ATTTCAGAGTTACCAAAGGGAAACAAAGAAGATAGCCTGAAAAAAATTAAAAGGACACCTTCTGCTACGTTTCAGCAAGCCACAAAGATT
AAAAAATTAAGAGCAGGTAAACTCTCTCCTCTCAAGTCTAAGTTTAAGACAGGGAAGCTTCAAATAGGAAGGAAGGGGGTACAAATTGTA
CGACGGAGAGGAAGGCCTCCATCAACAGAAAGGATAAAGACCCCTTCGGGTCTCCTCATTAATTCTGAACTGGAAAAGCCCCAGAAAGTC
CGGAAAGACAAGGAAGGAACACCTCCACTTACAAAAGAAGATAAGACAGTTGTCAGACAAAGCCCTCGAAGGATTAAGCCAGTTAGGATT
ATTCCTTCTTCAAAAAGGACAGATGCAACCATTGCTAAGCAACTCTTACAGAGGGCAAAAAAGGGGGCTCAAAAGAAAATTGAAAAAGAA
GCAGCTCAGCTGCAGGGAAGAAAGGTGAAGACACAGGTCAAAAATATTCGACAGTTCATCATGCCTGTTGTCAGTGCTATCTCCTCGCGG
ATCATTAAGACCCCTCGGCGGTTTATAGAGGATGAGGATTATGACCCTCCAATTAAAATTGCCCGATTAGAGTCTACACCGAATAGTAGA
TTCAGTGCCCCGTCCTGTGGATCTTCTGAAAAATCAAGTGCAGCTTCTCAGCACTCCTCTCAAATGTCTTCAGACTCCTCTCGATCTAGT
AGCCCCAGTGTTGATACCTCCACAGACTCTCAGGCTTCTGAGGAGATTCAGGTACTTCCTGAGGAGCGGAGCGATACCCCTGAAGTTCAT
CCTCCACTGCCCATTTCCCAGTCCCCAGAAAATGAGAGTAATGATAGGAGAAGCAGAAGGTATTCAGTGTCGGAGAGAAGTTTTGGATCT
AGAACGACGAAAAAATTATCAACTCTACAAAGTGCCCCCCAGCAGCAGACCTCCTCGTCTCCACCTCCACCTCTGCTGACTCCACCGCCA
CCACTGCAGCCAGCCTCCAGTATCTCTGACCACACACCTTGGCTTATGCCTCCAACAATCCCCTTAGCATCACCATTTTTGCCTGCTTCC
ACTGCTCCTATGCAAGGGAAGCGAAAATCTATTTTGCGAGAACCGACATTTAGGTGGACTTCTTTAAAGCATTCTAGGTCAGAGCCACAA
TACTTTTCCTCAGCAAAGTATGCCAAAGAAGGTCTTATTCGCAAACCAATATTTGATAATTTCCGACCCCCTCCACTAACTCCCGAGGAC
GTTGGCTTTGCATCTGGTTTTTCTGCATCTGGTACCGCTGCTTCAGCCCGATTGTTTTCGCCACTCCATTCTGGAACAAGGTTTGATATG
CACAAAAGGAGCCCTCTTCTGAGAGCTCCAAGATTTACTCCAAGTGAGGCTCACTCTAGAATATTTGAGTCTGTAACCTTGCCTAGTAAT
CGAACTTCTGCTGGAACATCTTCTTCAGGAGTATCCAATAGAAAAAGGAAAAGAAAAGTGTTTAGTCCTATTCGATCTGAACCAAGATCT
CCTTCTCACTCCATGAGGACAAGAAGTGGAAGGCTTAGTAGTTCTGAGCTCTCACCTCTCACCCCCCCGTCTTCTGTCTCTTCCTCGTTA
AGCATTTCTGTTAGTCCTCTTGCCACTAGTGCCTTAAACCCAACTTTTACTTTTCCTTCTCATTCCCTGACTCAGTCTGGGGAATCTGCA
GAGAAAAATCAGAGACCAAGGAAGCAGACTAGTGCTCCGGCAGAGCCATTTTCATCAAGTAGTCCTACTCCTCTCTTCCCTTGGTTTACC
CCAGGCTCTCAGACTGAAAGAGGGAGAAATAAAGACAAGGCCCCCGAGGAGCTGTCCAAAGATCGAGATGCTGACAAGAGCGTGGAGAAG
GACAAGAGTAGAGAGAGAGACCGGGAGAGAGAAAAGGAGAATAAGCGGGAGTCAAGGAAAGAGAAAAGGAAAAAGGGATCAGAAATTCAG
AGTAGTTCTGCTTTGTATCCTGTGGGTAGGGTTTCCAAAGAGAAGGTTGTTGGTGAAGATGTTGCCACTTCATCTTCTGCCAAAAAAGCA
ACAGGGCGGAAGAAGTCTTCATCACATGATTCTGGGACTGATATTACTTCTGTGACTCTTGGGGATACAACAGCTGTCAAAACCAAAATA
CTTATAAAGAAAGGGAGAGGAAATCTGGAAAAAACCAACTTGGACCTCGGCCCAACTGCCCCATCCCTGGAGAAGGAGAAAACCCTCTGC
CTTTCCACTCCTTCATCTAGCACTGTTAAACATTCCACTTCCTCCATAGGCTCCATGTTGGCTCAGGCAGACAAGCTTCCAATGACTGAC
AAGAGGGTTGCCAGCCTCCTAAAAAAGGCCAAAGCTCAGCTCTGCAAGATTGAGAAGAGTAAGAGTCTTAAACAAACCGACCAGCCCAAA
GCACAGGGTCAAGAAAGTGACTCATCAGAGACCTCTGTGCGAGGACCCCGGATTAAACATGTCTGCAGAAGAGCAGCTGTTGCCCTTGGC
CGAAAACGAGCTGTGTTTCCTGATGACATGCCCACCCTGAGTGCCTTACCATGGGAAGAACGAGAAAAGATTTTGTCTTCCATGGGGAAT
GATGACAAGTCATCAATTGCTGGCTCAGAAGATGCTGAACCTCTTGCTCCACCCATCAAACCAATTAAACCTGTCACTAGAAACAAGGCA
CCCCAGGAACCTCCAGTAAAGAAAGGACGTCGATCGAGGCGGTGTGGGCAGTGTCCCGGCTGCCAGGTGCCTGAGGACTGTGGTGTTTGT
ACTAATTGCTTAGATAAGCCCAAGTTTGGTGGTCGCAATATAAAGAAGCAGTGCTGCAAGATGAGAAAATGTCAGAATCTACAATGGATG
CCTTCCAAAGCCTACCTGCAGAAGCAAGCTAAAGCTGTGAAAAAGAAAGAGAAAAAGTCTAAGACCAGTGAAAAGAAAGACAGCAAAGAG
AGCAGTGTTGTGAAGAACGTGGTGGACTCTAGTCAGAAACCTACCCCATCAGCAAGAGAGGATCCTGCCCCAAAGAAAAGCAGTAGTGAG
CCTCCTCCACGAAAGCCCGTCGAGGAAAAGAGTGAAGAAGGGAATGTCTCGGCCCCTGGGCCTGAATCCAAACAGGCCACCACTCCAGCT
TCCAGGAAGTCAAGCAAGCAGGTCTCCCAGCCAGCACTGGTCATCCCGCCTCAGCCACCTACTACAGGACCGCCAAGAAAAGAAGTTCCC
AAAACCACTCCTAGTGAGCCCAAGAAAAAGCAGCCTCCACCACCAGAATCAGGTCCAGAGCAGAGCAAACAGAAAAAAGTGGCTCCCCGC
CCAAGTATCCCTGTAAAACAAAAACCAAAAGAAAAGGAGATGACCTGGCTTCCACCACTTTCTGCTATTCAAGCACCTGGCAAAGTGGAA
CCAACCAAATTTCCATTTCCAAATAAGGACTCTCAGCTTGTATCCTCTGGACACAATAATCCAAAGAAAGGTGATGCAGAGCCAGAGAGT
CCAGACAGTGGCACATCGAATACATCAATGCTGGAAGATGACCTTAAGCTAAGCAGTGATGAAGAGGAGAATGAACAGCAGGCAGCTCAG
AGAACGGCTCTCCGCGCTCTCTCTGACAGCGCCGTGGTCCAGCAGCCCAACTGCAGAACCTCGGTGCCTTCCAGCAAGGGCAGCAGCAGC
AGCAGCAGCAGCGGCAGCAGCAGCTCCTCCAGCGACTCAGAGAGCAGCTCCGGATCTGACTCGGAGACCGAGAGCAGCTCCAGCGAGAGT
GAGGGCAGCAAGCCCCCCCACTTCTCCAGCCCCGAGGCTGAACCGGCATCCTCTAACAAGTGGCAGCTGGATAAATGGCTAAACAAAGTT
AATCCCCACAAGCCTCCTATTCTGATCCAAAATGAAAGCCACGGGTCAGAGAGCAATCAGTACTACAACCCGGTGAAAGAGGACGTCCAG
GACTGTGGGAAAGTCCCCGACGTTTGCCAGCCCAGCCTGAGAGAGAAGGAGATCAAGAGCACTTGCAAGGAGGAGCAAAGGCCAAGGACA
GCCAACAAGGCCCCTGGGAGTAAAGGCGTGAAGCAGAAGTCCCCGCCCGCGGCCGTGGCCGTGGCGGTGAGCGCAGCCGCCCCGCCACCC
GCAGTGCCCTGTGCGCCCGCGGAGAACGCGCCCGCGCCTGCCCGGAGGTCCGCGGGCAAGAAGCCCACCAGGCGCACCGAGAGGACCTCA
GCCGGGGACGGCGCCAACTGCCACCGGCCCGAGGAGCCCGCGGCCGCGGACGCGCTGGGGACGAGCGTGGTGGTCCCCCCGGAGCCCACC
AAAACCAGGCCCTGTGGCAACAACAGAGCGAGCCACCGCAAGGAGCTGCGCTCCTCCGTGACCTGCGAGAAGCGCCGCACGCGGGGGCTA
AGCAGGATCGTCCCCAAATCCAAGGAGTTCATTGAGACAGAGTCGTCATCTTCATCCTCCTCCTCGGACTCCGACCTGGAGTCCGAGCAG
GAGGAGTACCCTCTGTCCAAAGCACAGACCGTGGCTGCCTCTGCCTCCTCCGGGAATGATCAGAGGCTGAAGGAGGCCGCTGCCAACGGG
GGCAGTGGTCCTAGGGCCCCTGTAGGCTCCATCAACGCCAGGACCACCAGTGACATCGCCAAGGAGCTGGAGGAGCAGTTCTACACACTG
GTCCCCTTTGGCCGGAACGAACTTCTCTCCCCTCTAAAGGACAGTGATGAGATCAGGTCTCTCTGGGTCAAAATCGACCTGACCCTCCTG
TCCAGGATCCCAGAACACCTGCCCCAGGAGCCAGGGGTATTGAGCGCCCCTGCCACCAAGGACTCTGAGAGCGCACCGCCCAGCCACACC
TCGGACACACCTGCAGAAAAGGCTTTGCCAAAATCCAAGAGGAAACGCAAGTGTGACAACGAAGACGACTACAGGGAGATCAAGAAGTCC
CAGGGAGAGAAAGACAGCTCTTCAAGACTGGCCACCTCCACCAGTAATACTTTGTCTGCAAACCACTGCAACATGAACATCAACAGTGTG
GCAATACCAATAAATAAAAATGAAAAAATGCTTCGGTCGCCCATCTCACCCCTCTCTGATGCATCTAAACACAAATACACCAGCGAGGAC
TTAACTTCTTCCAGCCGACCTAATGGCAACAGTTTGTTTACTTCAGCCTCTTCCAGCAAAAAGCCTAAGGCCGACAGCCAGCTGCAGCCT
CACGGCGGAGACCTCACGAAAGCAGCTCACAACAATTCTGAAAACATTCCCCTCCACAAGTCACGGCCGCAGACGAAGCCGTGGTCTCCA
GGCTCCAACGGCCACAGGGACTGCAAGAGGCAGAAACTTGTCTTCGATGATATGCCTCGCAGTGCCGATTATTTTATGCAAGAAGCTAAA
CGAATGAAGCATAAAGCAGATGCAATGGTGGAAAAGTTTGGAAAGGCTTTGAACTATGCTGAAGCAGCATTGTCGTTTATCGAGTGTGGA
AATGCAATGGAACAAGGCCCCATGGAATCCAAATCTCCTTATACGATGTATTCAGAAACAGTAGAGCTCATCAGGTATGCTATGAGACTA
AAAACCCACTCAGGCCCCAATGCCACACCAGAAGACAAACAACTGGCTGCATTATGTTACCGATGCCTGGCCCTCCTGTACTGGCGGATG
TTTCGACTCAAAAGGGACCACGCTGTAAAGTATTCAAAAGCACTAATCGACTATTTCAAGAACTCATCTAAAGCCGCCCAAGCCCCATCT
CCGTGGGGGGCCAGTGGAAAGAGCACTGGAACCCCATCCCCCATGTCTCCCAACCCCTCTCCCGCCAGCTCCGTGGGGTCTCAGGGCAGC
CTCTCCAACGCCAGCGCCCTGTCCCCGTCGACCATCGTCAGCATCCCACAGCGCATCCACCAGATGGCGGCCAACCACGTCAGCATCACC
AACAGCATCCTGCACAGCTACGACTACTGGGAGATGGCCGACAACCTGGCCAAGGAAAACCGAGAATTCTTCAACGACCTGGATCTGCTC
ATGGGGCCGGTCACCCTGCACAGCAGCATGGAGCACCTGGTCCAGTACTCCCAACAGGGCCTGCACTGGCTGCGGAACAGCGCCCACCTG
TCATAGGGACCTCACCCTGGGGCCAGAGTGGGCTCTGGTCTCCACAGATGGCTCAACGTTTTTGGACACTGTGCTACTGAAACTCCCAGC
CACAGCATTTATCAGACTGCGGTGAACATTTCCTCAGCATTGAACAATGATCTTTTGCAGGGCATGTGTGTTTGTATGTGTGGGTATATA
AGAAGCCGCCTGTGTATGTGTGTAAGATACACAGCTCTTCAGAACACACCTTCTTTGTCTAGTTTCCATAATCCCAGGCTAGACAAAGTG
ATCAGAGGTTTCTGACTAGAGGAAGTACACACACACACACACACACACACACACACCGTACACTCACACACAATCACAGACACACACTTT
CTATTCCATTCCAGTGCTAAACCGTGACTTCTTAGAAAATTCAACCAAAATCTCATGGGTTAGTTAACCAGGTGCAATACAGCACACCAA
AAGCTTGACTGCCAGTGAAGATGGACCTGCTCTTATACTGTTGATTACTTTCAGTATTAATATACTATTCCCCAATTATTTTTTGATTGG
TATGTATTAATGGGTAATTGAATAATGAAAATAAGCCAGGTATTTTTGTGCCGGAAGTTTACTAGATTGCATGTTACCAAATACCCTGCT
CTTCCTCTAATTCCCTTCCCCCATCTGACTCTATTATCAACTAAATGCATTCCAGGCAAACAGATGGACACTCACAGCCCTTCCCAGCCC
CACCTCCAAGTAGTATGCAAATGGCACTGAGATTTAGCAAAAACGCGGCGTCTTTGAAAGTTAACAGACACTAAGGTAGCAGTGCCTGTG
TGTTGGAGCTCAGTTAGGAGTTGAAGTTTTCTGCACCTGTGATAACAAGCCCACCAGCCACATGCATTTCTTCTTCCTGCCACTGTGACT
CGGTGGCTGTAGAGCCACATGGCATTTGTCAGCCAATCTGTTTCAAGTCTTTTCTTTCCACCAATAGCTTTCTTACAGATTTTCTTGGCT
AAATGAGGCCATTACCTAGATTGTCCCTTCAGTAGGAGCCTGAATCCTTCGCTTACCAGGCTGAGAGCTATTTGCCATGATAATGCTGAT
TCTCTCACTCCTCATGCAGAATGTGCACCTGCAGCCCTTTGATGCGTTTTGATTTGGGGGCGATTTTTCAGGCTTTGATTAGCAGGCTGC
TTGCAATGCAGAAGATCACAGTTCCTTTCTGGGGCAGCAGCAACCAGAGCCTCTTCCTGTGTCCTGTGTGTCTGGTATGTTTACACCTTG
CTCTGAGTTTTTCTCTTGTTTTCTTTTTTTAATTAAGTTTACATTTTAGTTTCTTTGACATCTTGTTTACAGTTTTTGTCTGATGTTTTT
TCTTTTGTAGTGTCTTATGCCCTAGATTTAGTCATCTTGTTAAATATATTTGGATATGAAATCTTGACGAAAAGAAAATAACTCCTGAAA
AAGAGGGTCTATCTTGCCACACGTTAAAAACAAAAATAATGTCCTTGTGGCCTCTTACTTGATAAAGTTGCACCAGGACGGTCTGAGAAA
GGCAGGCGGTGTAATATGTGGTGCAATCCATTTTTTCAAGGTGATGACGGCACAAAATACTTAGACTAGATGCTGATCCATAAACATTCA
CTGATATTCTTACAGGTTGGTTTGCAGTGTTAACATTTTTGTTAGCCTGATCTGTAGGTGGGAAGTAAGATCATCATAATTCCTTAGCTC
TGAGCACTGATTCAAAATTGTATAAATGACTGAACAACTTAGATGATTTGAAATTAATTGAAAATAAGAAGGGCTTGTGGAATTTGCATT
TGGCTTTGGCCTTCAAGCATTTGGAAATATTAAGAGAATTTCCATTTTACATGTCTCCAACTGGGGTGCTTCTTACAACCCTTTCACTTT
TTTTTTGAGACGAGTTTCGCTCTGTTGCCCAGGCTGGAGTGCAGTGGCACGATCTCGGCTCACTGCATCCTCTGCCTCCTGGGTTCAAGT
GATTGTCCCGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGTGTGCACTACCATGCCCAGCTAATTTTTGTGTTTTTAGTAGAGACTGGG
TTTCACCATGTTGGCCAGGCTCGTCTCAAACTCCTGACCTCAGGTGATCTACCCGCCTCCACCTCCCAAAGTGTTGTGATTACAGGCGTG
AGCCACCACACCCAGCCCTTTCACTAATTTTTGGCAGAGTTCACAATCCCATCCTATGTCAGAAACTTGAACCTAACTTAAGAAATTTTG
AGTCATTTTTTTGGAGGACTGAGGCTTTGTTCTACCTACTCTTGAAGAATCCTGATGAAATATTCAAACACATAAAGGGATGGCCCTGGA
GGTCTATCCTGCATACCTGGAGAGCTTCTCTGGTCCTGCCCACCTTGAAAGTTGCAGACTTTGTTGTAACATCTATGTGATGAGCTTCCC
TGTGAAGCCCCATTTGACAGGTGGGCCAGCAGTGTTTTATCAGCACTCTGATGGCCCACATTTCCCAGGAAAACTTCTTGAAACTTACCG
TTGTGGGCAGTGGTCAGAGCGTGTAGTTCTTATGACTGTCTTGTTTCATCTGTGGAGCACGTGTGGAGCACGTTGGTACAGCAGTTTCTG
TGGGGTTTGGCATGGGTGATTTTGGTTAGTAACCATCCTCCAATTGTTGCTTGTGAAAGTCATTCATAACTTGTTCCTTTTACTTAGTTT
TGTTGTTACTGCTGTTGTTGTTGGTTTGGTTGGTTTTGAGACCGGGTCTGGCTCTGTAGCCCAAGCTGGAATGCGGTGGCGCGATCATGG
CTCCCTGCAGCCTCAAACTCCTGGGCTCAAGCAATCCTCCTGCCTCAGCCTCCCAAGCAGCTGGGAAGATAGGCACGTGCCACCACACCC
GGCTAATTTTTTCTTTATTTTTTTTGTAGAGATGGGGGTCTCACTATGTTGCCCAGGCTGGTCTCAAACTCCTGGGCTCAAGCGATCCTT
TGGCCTCGGCCTCCCAAAGTGCATGAGCCACCATGCCTGGCCTGTTTAGTTTTGTTTCAAGTTGAAATACCTTTCTTGTGTTTTCTAATT
AGAAAAGTAATATCTACTCATTGTAAAAACTCAAACAGTGCAGAAATGTAGAAAGTAGAAAGTGTAAGTCCCTGGTTGTCCCTTCTGCCT
GAGACAACCACTGCTCACAGTTTGATGTATATCCTTCCAGAGACTCTCAAATTTAAGCAAATAATTTTTATTACCATGTCTTTTTATTTG
AAGACGTACATTTGCCTCCAAAGTTCAACACAAGTTCAACTGACCATATCCTTCCATGACCTGAATAGATGCTATCCTTTATCACGATGT
TCAATTGCCTTTGAAAGAGAGTAGTCCAGGTATATTCCTGATCAAAATTTGGCATTTTTGATGATACTACTCTACACAGATCAGACTCAT
GTGCAGAATCGTGCCTGGAGAGAGAGGTTTGGTTAAGACAGAGATTTCTGGAAACATTCAAATTGCAAATGGAAACTTGAAACCCACAAT
CTAATGAGGAATGTACTGGAAAAATAATCTGAAGAGTTGACAAATTGTGTACTAGATTGAACACATGGAATGCAATGCAATGAGACTTTC
TGCACTAAAACTTATCCTCATATGTACAACAATGATGTGTGTATTATATAACAGTGATGTGTACATTTCTGACACCCCATACATAATATA
CACAGTTTGTATAAATGCATACATTTAAAAATATATATGTACAATACAGCTAACATAAAACTGTAGTACGCCTGAAGGATATTACTAGTG
CCTAATATTGAGTATGAGTCACTGCGTGTTCGCATCAACTTGGAAGTGCAGTAATTGTTATAAAATTAATCAGTGCAGCCAACATTATTT
ATGAATCACATCTTTGAAACTGTGCAGTAGCATATACATATATATTTTTAAATAACATTTTTCACAGTTTTCCAGAGTTACTGTTGAAAT
CTGCATCACCAAAAAAAAAAAAAAGCAAGATTTTTTTAACAATGTAGACACTCTTCAGACCCAGTAATCTGCGTGTGATTTCCTATTTGT
AGATTCCCAAGAGACTTTAGCAGTCACCAGCCTTAATGCATGTACAGGATATTATTGTGACTTAATTTATCTGCAGTTTTTAATCCATGT

>In-frame_ENST00000389506_ENST00000317233_AF422798_KMT2A_chr11_118353211_+_AFF3_chr2_100368765_length(amino acids)=2281AA_start in transcript=0_stop in transcript=6845
MAHSCRWRFPARPGTTGGGGGGGRRGLGGAPRQRVPALLLPPGPPVGGGGPGAPPSPPAVAAAAAAAGSSGAGVPGGAAAASAASSSSAS
SSSSSSSSASSGPALLRVGPGFDAALQVSAAIGTNLRRFRAVFGESGGGGGSGEDEQFLGFGSDEEVRVRSPTRSPSVKTSPRKPRGRPR
SGSDRNSAILSDPSVFSPLNKSETKSGDKIKKKDSKSIEKKRGRPPTFPGVKIKITHGKDISELPKGNKEDSLKKIKRTPSATFQQATKI
KKLRAGKLSPLKSKFKTGKLQIGRKGVQIVRRRGRPPSTERIKTPSGLLINSELEKPQKVRKDKEGTPPLTKEDKTVVRQSPRRIKPVRI
IPSSKRTDATIAKQLLQRAKKGAQKKIEKEAAQLQGRKVKTQVKNIRQFIMPVVSAISSRIIKTPRRFIEDEDYDPPIKIARLESTPNSR
FSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGS
RTTKKLSTLQSAPQQQTSSSPPPPLLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQ
YFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSN
RTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESA
EKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQ
SSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKILIKKGRGNLEKTNLDLGPTAPSLEKEKTLC
LSTPSSSTVKHSTSSIGSMLAQADKLPMTDKRVASLLKKAKAQLCKIEKSKSLKQTDQPKAQGQESDSSETSVRGPRIKHVCRRAAVALG
RKRAVFPDDMPTLSALPWEEREKILSSMGNDDKSSIAGSEDAEPLAPPIKPIKPVTRNKAPQEPPVKKGRRSRRCGQCPGCQVPEDCGVC
TNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKSSSE
PPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPR
PSIPVKQKPKEKEMTWLPPLSAIQAPGKVEPTKFPFPNKDSQLVSSGHNNPKKGDAEPESPDSGTSNTSMLEDDLKLSSDEEENEQQAAQ
RTALRALSDSAVVQQPNCRTSVPSSKGSSSSSSSGSSSSSSDSESSSGSDSETESSSSESEGSKPPHFSSPEAEPASSNKWQLDKWLNKV
NPHKPPILIQNESHGSESNQYYNPVKEDVQDCGKVPDVCQPSLREKEIKSTCKEEQRPRTANKAPGSKGVKQKSPPAAVAVAVSAAAPPP
AVPCAPAENAPAPARRSAGKKPTRRTERTSAGDGANCHRPEEPAAADALGTSVVVPPEPTKTRPCGNNRASHRKELRSSVTCEKRRTRGL
SRIVPKSKEFIETESSSSSSSSDSDLESEQEEYPLSKAQTVAASASSGNDQRLKEAAANGGSGPRAPVGSINARTTSDIAKELEEQFYTL
VPFGRNELLSPLKDSDEIRSLWVKIDLTLLSRIPEHLPQEPGVLSAPATKDSESAPPSHTSDTPAEKALPKSKRKRKCDNEDDYREIKKS
QGEKDSSSRLATSTSNTLSANHCNMNINSVAIPINKNEKMLRSPISPLSDASKHKYTSEDLTSSSRPNGNSLFTSASSSKKPKADSQLQP
HGGDLTKAAHNNSENIPLHKSRPQTKPWSPGSNGHRDCKRQKLVFDDMPRSADYFMQEAKRMKHKADAMVEKFGKALNYAEAALSFIECG
NAMEQGPMESKSPYTMYSETVELIRYAMRLKTHSGPNATPEDKQLAALCYRCLALLYWRMFRLKRDHAVKYSKALIDYFKNSSKAAQAPS
PWGASGKSTGTPSPMSPNPSPASSVGSQGSLSNASALSPSTIVSIPQRIHQMAANHVSITNSILHSYDYWEMADNLAKENREFFNDLDLL

--------------------------------------------------------------
>In-frame_ENST00000389506_ENST00000409579_AF422798_KMT2A_chr11_118353211_+_AFF3_chr2_100368765_length(transcript)=7199nt_BP=4086nt
ATGGCGCACAGCTGTCGGTGGCGCTTCCCCGCCCGACCCGGGACCACCGGGGGCGGCGGCGGCGGGGGGCGCCGGGGCCTAGGGGGCGCC
CCGCGGCAACGCGTCCCGGCCCTGCTGCTTCCCCCCGGGCCCCCGGTCGGCGGTGGCGGCCCCGGGGCGCCCCCCTCCCCCCCGGCTGTG
GCGGCCGCGGCGGCGGCGGCGGGAAGCAGCGGGGCTGGGGTTCCAGGGGGAGCGGCCGCCGCCTCAGCAGCCTCCTCGTCGTCCGCCTCG
TCTTCGTCTTCGTCATCGTCCTCAGCCTCTTCAGGGCCGGCCCTGCTCCGGGTGGGCCCGGGCTTCGACGCGGCGCTGCAGGTCTCGGCC
GCCATCGGCACCAACCTGCGCCGGTTCCGGGCCGTGTTTGGGGAGAGCGGCGGGGGAGGCGGCAGCGGAGAGGATGAGCAATTCTTAGGT
TTTGGCTCAGATGAAGAAGTCAGAGTGCGAAGTCCCACAAGGTCTCCTTCAGTTAAAACTAGTCCTCGAAAACCTCGTGGGAGACCTAGA
AGTGGCTCTGACCGAAATTCAGCTATCCTCTCAGATCCATCTGTGTTTTCCCCTCTAAATAAATCAGAGACCAAATCTGGAGATAAGATC
AAGAAGAAAGATTCTAAAAGTATAGAAAAGAAGAGAGGAAGACCTCCCACCTTCCCTGGAGTAAAAATCAAAATAACACATGGAAAGGAC
ATTTCAGAGTTACCAAAGGGAAACAAAGAAGATAGCCTGAAAAAAATTAAAAGGACACCTTCTGCTACGTTTCAGCAAGCCACAAAGATT
AAAAAATTAAGAGCAGGTAAACTCTCTCCTCTCAAGTCTAAGTTTAAGACAGGGAAGCTTCAAATAGGAAGGAAGGGGGTACAAATTGTA
CGACGGAGAGGAAGGCCTCCATCAACAGAAAGGATAAAGACCCCTTCGGGTCTCCTCATTAATTCTGAACTGGAAAAGCCCCAGAAAGTC
CGGAAAGACAAGGAAGGAACACCTCCACTTACAAAAGAAGATAAGACAGTTGTCAGACAAAGCCCTCGAAGGATTAAGCCAGTTAGGATT
ATTCCTTCTTCAAAAAGGACAGATGCAACCATTGCTAAGCAACTCTTACAGAGGGCAAAAAAGGGGGCTCAAAAGAAAATTGAAAAAGAA
GCAGCTCAGCTGCAGGGAAGAAAGGTGAAGACACAGGTCAAAAATATTCGACAGTTCATCATGCCTGTTGTCAGTGCTATCTCCTCGCGG
ATCATTAAGACCCCTCGGCGGTTTATAGAGGATGAGGATTATGACCCTCCAATTAAAATTGCCCGATTAGAGTCTACACCGAATAGTAGA
TTCAGTGCCCCGTCCTGTGGATCTTCTGAAAAATCAAGTGCAGCTTCTCAGCACTCCTCTCAAATGTCTTCAGACTCCTCTCGATCTAGT
AGCCCCAGTGTTGATACCTCCACAGACTCTCAGGCTTCTGAGGAGATTCAGGTACTTCCTGAGGAGCGGAGCGATACCCCTGAAGTTCAT
CCTCCACTGCCCATTTCCCAGTCCCCAGAAAATGAGAGTAATGATAGGAGAAGCAGAAGGTATTCAGTGTCGGAGAGAAGTTTTGGATCT
AGAACGACGAAAAAATTATCAACTCTACAAAGTGCCCCCCAGCAGCAGACCTCCTCGTCTCCACCTCCACCTCTGCTGACTCCACCGCCA
CCACTGCAGCCAGCCTCCAGTATCTCTGACCACACACCTTGGCTTATGCCTCCAACAATCCCCTTAGCATCACCATTTTTGCCTGCTTCC
ACTGCTCCTATGCAAGGGAAGCGAAAATCTATTTTGCGAGAACCGACATTTAGGTGGACTTCTTTAAAGCATTCTAGGTCAGAGCCACAA
TACTTTTCCTCAGCAAAGTATGCCAAAGAAGGTCTTATTCGCAAACCAATATTTGATAATTTCCGACCCCCTCCACTAACTCCCGAGGAC
GTTGGCTTTGCATCTGGTTTTTCTGCATCTGGTACCGCTGCTTCAGCCCGATTGTTTTCGCCACTCCATTCTGGAACAAGGTTTGATATG
CACAAAAGGAGCCCTCTTCTGAGAGCTCCAAGATTTACTCCAAGTGAGGCTCACTCTAGAATATTTGAGTCTGTAACCTTGCCTAGTAAT
CGAACTTCTGCTGGAACATCTTCTTCAGGAGTATCCAATAGAAAAAGGAAAAGAAAAGTGTTTAGTCCTATTCGATCTGAACCAAGATCT
CCTTCTCACTCCATGAGGACAAGAAGTGGAAGGCTTAGTAGTTCTGAGCTCTCACCTCTCACCCCCCCGTCTTCTGTCTCTTCCTCGTTA
AGCATTTCTGTTAGTCCTCTTGCCACTAGTGCCTTAAACCCAACTTTTACTTTTCCTTCTCATTCCCTGACTCAGTCTGGGGAATCTGCA
GAGAAAAATCAGAGACCAAGGAAGCAGACTAGTGCTCCGGCAGAGCCATTTTCATCAAGTAGTCCTACTCCTCTCTTCCCTTGGTTTACC
CCAGGCTCTCAGACTGAAAGAGGGAGAAATAAAGACAAGGCCCCCGAGGAGCTGTCCAAAGATCGAGATGCTGACAAGAGCGTGGAGAAG
GACAAGAGTAGAGAGAGAGACCGGGAGAGAGAAAAGGAGAATAAGCGGGAGTCAAGGAAAGAGAAAAGGAAAAAGGGATCAGAAATTCAG
AGTAGTTCTGCTTTGTATCCTGTGGGTAGGGTTTCCAAAGAGAAGGTTGTTGGTGAAGATGTTGCCACTTCATCTTCTGCCAAAAAAGCA
ACAGGGCGGAAGAAGTCTTCATCACATGATTCTGGGACTGATATTACTTCTGTGACTCTTGGGGATACAACAGCTGTCAAAACCAAAATA
CTTATAAAGAAAGGGAGAGGAAATCTGGAAAAAACCAACTTGGACCTCGGCCCAACTGCCCCATCCCTGGAGAAGGAGAAAACCCTCTGC
CTTTCCACTCCTTCATCTAGCACTGTTAAACATTCCACTTCCTCCATAGGCTCCATGTTGGCTCAGGCAGACAAGCTTCCAATGACTGAC
AAGAGGGTTGCCAGCCTCCTAAAAAAGGCCAAAGCTCAGCTCTGCAAGATTGAGAAGAGTAAGAGTCTTAAACAAACCGACCAGCCCAAA
GCACAGGGTCAAGAAAGTGACTCATCAGAGACCTCTGTGCGAGGACCCCGGATTAAACATGTCTGCAGAAGAGCAGCTGTTGCCCTTGGC
CGAAAACGAGCTGTGTTTCCTGATGACATGCCCACCCTGAGTGCCTTACCATGGGAAGAACGAGAAAAGATTTTGTCTTCCATGGGGAAT
GATGACAAGTCATCAATTGCTGGCTCAGAAGATGCTGAACCTCTTGCTCCACCCATCAAACCAATTAAACCTGTCACTAGAAACAAGGCA
CCCCAGGAACCTCCAGTAAAGAAAGGACGTCGATCGAGGCGGTGTGGGCAGTGTCCCGGCTGCCAGGTGCCTGAGGACTGTGGTGTTTGT
ACTAATTGCTTAGATAAGCCCAAGTTTGGTGGTCGCAATATAAAGAAGCAGTGCTGCAAGATGAGAAAATGTCAGAATCTACAATGGATG
CCTTCCAAAGCCTACCTGCAGAAGCAAGCTAAAGCTGTGAAAAAGAAAGAGAAAAAGTCTAAGACCAGTGAAAAGAAAGACAGCAAAGAG
AGCAGTGTTGTGAAGAACGTGGTGGACTCTAGTCAGAAACCTACCCCATCAGCAAGAGAGGATCCTGCCCCAAAGAAAAGCAGTAGTGAG
CCTCCTCCACGAAAGCCCGTCGAGGAAAAGAGTGAAGAAGGGAATGTCTCGGCCCCTGGGCCTGAATCCAAACAGGCCACCACTCCAGCT
TCCAGGAAGTCAAGCAAGCAGGTCTCCCAGCCAGCACTGGTCATCCCGCCTCAGCCACCTACTACAGGACCGCCAAGAAAAGAAGTTCCC
AAAACCACTCCTAGTGAGCCCAAGAAAAAGCAGCCTCCACCACCAGAATCAGGTCCAGAGCAGAGCAAACAGAAAAAAGTGGCTCCCCGC
CCAAGTATCCCTGTAAAACAAAAACCAAAAGAAAAGGAGATGACCTGGCTTCCACCACTTTCTGCTATTCAAGCACCTGGCAAAGTGGAA
CCAACCAAATTTCCATTTCCAAATAAGGACTCTCAGCTTGTATCCTCTGGACACAATAATCCAAAGAAAGGTGATGCAGAGCCAGAGAGT
CCAGACAGTGGCACATCGAATACATCAATGCTGGAAGATGACCTTAAGCTAAGCAGTGATGAAGAGGAGAATGAACAGCAGGCAGCTCAG
AGAACGGCTCTCCGCGCTCTCTCTGACAGCGCCGTGGTCCAGCAGCCCAACTGCAGAACCTCGGTGCCTTCCAGCAAGGGCAGCAGCAGC
AGCAGCAGCAGCGGCAGCAGCAGCTCCTCCAGCGACTCAGAGAGCAGCTCCGGATCTGACTCGGAGACCGAGAGCAGCTCCAGCGAGAGT
GAGGGCAGCAAGCCCCCCCACTTCTCCAGCCCCGAGGCTGAACCGGCATCCTCTAACAAGTGGCAGCTGGATAAATGGCTAAACAAAGTT
AATCCCCACAAGCCTCCTATTCTGATCCAAAATGAAAGCCACGGGTCAGAGAGCAATCAGTACTACAACCCGGTGAAAGAGGACGTCCAG
GACTGTGGGAAAGTCCCCGACGTTTGCCAGCCCAGCCTGAGAGAGAAGGAGATCAAGAGCACTTGCAAGGAGGAGCAAAGGCCAAGGACA
GCCAACAAGGCCCCTGGGAGTAAAGGCGTGAAGCAGAAGTCCCCGCCCGCGGCCGTGGCCGTGGCGGTGAGCGCAGCCGCCCCGCCACCC
GCAGTGCCCTGTGCGCCCGCGGAGAACGCGCCCGCGCCTGCCCGGAGGTCCGCGGGCAAGAAGCCCACCAGGCGCACCGAGAGGACCTCA
GCCGGGGACGGCGCCAACTGCCACCGGCCCGAGGAGCCCGCGGCCGCGGACGCGCTGGGGACGAGCGTGGTGGTCCCCCCGGAGCCCACC
AAAACCAGGCCCTGTGGCAACAACAGAGCGAGCCACCGCAAGGAGCTGCGCTCCTCCGTGACCTGCGAGAAGCGCCGCACGCGGGGGCTA
AGCAGGATCGTCCCCAAATCCAAGGAGTTCATTGAGACAGAGTCGTCATCTTCATCCTCCTCCTCGGACTCCGACCTGGAGTCCGAGCAG
GAGGAGTACCCTCTGTCCAAAGCACAGACCGTGGCTGCCTCTGCCTCCTCCGGGAATGATCAGAGGCTGAAGGAGGCCGCTGCCAACGGG
GGCAGTGGTCCTAGGGCCCCTGTAGGCTCCATCAACGCCAGGACCACCAGTGACATCGCCAAGGAGCTGGAGGAGCAGTTCTACACACTG
GTCCCCTTTGGCCGGAACGAACTTCTCTCCCCTCTAAAGGACAGTGATGAGATCAGGTCTCTCTGGGTCAAAATCGACCTGACCCTCCTG
TCCAGGATCCCAGAACACCTGCCCCAGGAGCCAGGGGTATTGAGCGCCCCTGCCACCAAGGACTCTGAGAGCGCACCGCCCAGCCACACC
TCGGACACACCTGCAGAAAAGGCTTTGCCAAAATCCAAGAGGAAACGCAAGTGTGACAACGAAGACGACTACAGGGAGATCAAGAAGTCC
CAGGGAGAGAAAGACAGCTCTTCAAGACTGGCCACCTCCACCAGTAATACTTTGTCTGCAAACCACTGCAACATGAACATCAACAGTGTG
GCAATACCAATAAATAAAAATGAAAAAATGCTTCGGTCGCCCATCTCACCCCTCTCTGATGCATCTAAACACAAATACACCAGCGAGGAC
TTAACTTCTTCCAGCCGACCTAATGGCAACAGTTTGTTTACTTCAGCCTCTTCCAGCAAAAAGCCTAAGGCCGACAGCCAGCTGCAGCCT
CACGGCGGAGACCTCACGAAAGCAGCTCACAACAATTCTGAAAACATTCCCCTCCACAAGTCACGGCCGCAGACGAAGCCGTGGTCTCCA
GGCTCCAACGGCCACAGGGACTGCAAGAGGCAGAAACTTGTCTTCGATGATATGCCTCGCAGTGCCGATTATTTTATGCAAGAAGCTAAA
CGAATGAAGCATAAAGCAGATGCAATGGTGGAAAAGTTTGGAAAGGCTTTGAACTATGCTGAAGCAGCATTGTCGTTTATCGAGTGTGGA
AATGCAATGGAACAAGGCCCCATGGAATCCAAATCTCCTTATACGATGTATTCAGAAACAGTAGAGCTCATCAGGTATGCTATGAGACTA
AAAACCCACTCAGGCCCCAATGCCACACCAGAAGACAAACAACTGGCTGCATTATGTTACCGATGCCTGGCCCTCCTGTACTGGCGGATG
TTTCGACTCAAAAGGGACCACGCTGTAAAGTATTCAAAAGCACTAATCGACTATTTCAAGAACTCATCTAAAGCCGCCCAAGCCCCATCT
CCGTGGGGGGCCAGTGGAAAGAGCACTGGAACCCCATCCCCCATGTCTCCCAACCCCTCTCCCGCCAGCTCCGTGGGGTCTCAGGGCAGC
CTCTCCAACGCCAGCGCCCTGTCCCCGTCGACCATCGTCAGCATCCCACAGCGCATCCACCAGATGGCGGCCAACCACGTCAGCATCACC
AACAGCATCCTGCACAGCTACGACTACTGGGAGATGGCCGACAACCTGGCCAAGGAAAACCGAGAATTCTTCAACGACCTGGATCTGCTC
ATGGGGCCGGTCACCCTGCACAGCAGCATGGAGCACCTGGTCCAGTACTCCCAACAGGGCCTGCACTGGCTGCGGAACAGCGCCCACCTG
TCATAGGGACCTCACCCTGGGGCCAGAGTGGGCTCTGGTCTCCACAGATGGCTCAACGTTTTTGGACACTGTGCTACTGAAACTCCCAGC
CACAGCATTTATCAGACTGCGGTGAACATTTCCTCAGCATTGAACAATGATCTTTTGCAGGGCATGTGTGTTTGTATGTGTGGGTATATA
AGAAGCCGCCTGTGTATGTGTGTAAGATACACAGCTCTTCAGAACACACCTTCTTTGTCTAGTTTCCATAATCCCAGGCTAGACAAAGTG

>In-frame_ENST00000389506_ENST00000409579_AF422798_KMT2A_chr11_118353211_+_AFF3_chr2_100368765_length(amino acids)=2281AA_start in transcript=0_stop in transcript=6845
MAHSCRWRFPARPGTTGGGGGGGRRGLGGAPRQRVPALLLPPGPPVGGGGPGAPPSPPAVAAAAAAAGSSGAGVPGGAAAASAASSSSAS
SSSSSSSSASSGPALLRVGPGFDAALQVSAAIGTNLRRFRAVFGESGGGGGSGEDEQFLGFGSDEEVRVRSPTRSPSVKTSPRKPRGRPR
SGSDRNSAILSDPSVFSPLNKSETKSGDKIKKKDSKSIEKKRGRPPTFPGVKIKITHGKDISELPKGNKEDSLKKIKRTPSATFQQATKI
KKLRAGKLSPLKSKFKTGKLQIGRKGVQIVRRRGRPPSTERIKTPSGLLINSELEKPQKVRKDKEGTPPLTKEDKTVVRQSPRRIKPVRI
IPSSKRTDATIAKQLLQRAKKGAQKKIEKEAAQLQGRKVKTQVKNIRQFIMPVVSAISSRIIKTPRRFIEDEDYDPPIKIARLESTPNSR
FSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGS
RTTKKLSTLQSAPQQQTSSSPPPPLLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQ
YFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSN
RTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESA
EKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQ
SSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKILIKKGRGNLEKTNLDLGPTAPSLEKEKTLC
LSTPSSSTVKHSTSSIGSMLAQADKLPMTDKRVASLLKKAKAQLCKIEKSKSLKQTDQPKAQGQESDSSETSVRGPRIKHVCRRAAVALG
RKRAVFPDDMPTLSALPWEEREKILSSMGNDDKSSIAGSEDAEPLAPPIKPIKPVTRNKAPQEPPVKKGRRSRRCGQCPGCQVPEDCGVC
TNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKSSSE
PPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPR
PSIPVKQKPKEKEMTWLPPLSAIQAPGKVEPTKFPFPNKDSQLVSSGHNNPKKGDAEPESPDSGTSNTSMLEDDLKLSSDEEENEQQAAQ
RTALRALSDSAVVQQPNCRTSVPSSKGSSSSSSSGSSSSSSDSESSSGSDSETESSSSESEGSKPPHFSSPEAEPASSNKWQLDKWLNKV
NPHKPPILIQNESHGSESNQYYNPVKEDVQDCGKVPDVCQPSLREKEIKSTCKEEQRPRTANKAPGSKGVKQKSPPAAVAVAVSAAAPPP
AVPCAPAENAPAPARRSAGKKPTRRTERTSAGDGANCHRPEEPAAADALGTSVVVPPEPTKTRPCGNNRASHRKELRSSVTCEKRRTRGL
SRIVPKSKEFIETESSSSSSSSDSDLESEQEEYPLSKAQTVAASASSGNDQRLKEAAANGGSGPRAPVGSINARTTSDIAKELEEQFYTL
VPFGRNELLSPLKDSDEIRSLWVKIDLTLLSRIPEHLPQEPGVLSAPATKDSESAPPSHTSDTPAEKALPKSKRKRKCDNEDDYREIKKS
QGEKDSSSRLATSTSNTLSANHCNMNINSVAIPINKNEKMLRSPISPLSDASKHKYTSEDLTSSSRPNGNSLFTSASSSKKPKADSQLQP
HGGDLTKAAHNNSENIPLHKSRPQTKPWSPGSNGHRDCKRQKLVFDDMPRSADYFMQEAKRMKHKADAMVEKFGKALNYAEAALSFIECG
NAMEQGPMESKSPYTMYSETVELIRYAMRLKTHSGPNATPEDKQLAALCYRCLALLYWRMFRLKRDHAVKYSKALIDYFKNSSKAAQAPS
PWGASGKSTGTPSPMSPNPSPASSVGSQGSLSNASALSPSTIVSIPQRIHQMAANHVSITNSILHSYDYWEMADNLAKENREFFNDLDLL

--------------------------------------------------------------
>In-frame_ENST00000354520_ENST00000409236_AF422798_KMT2A_chr11_118353211_+_AFF3_chr2_100368765_length(transcript)=12459nt_BP=4086nt
ATGGCGCACAGCTGTCGGTGGCGCTTCCCCGCCCGACCCGGGACCACCGGGGGCGGCGGCGGCGGGGGGCGCCGGGGCCTAGGGGGCGCC
CCGCGGCAACGCGTCCCGGCCCTGCTGCTTCCCCCCGGGCCCCCGGTCGGCGGTGGCGGCCCCGGGGCGCCCCCCTCCCCCCCGGCTGTG
GCGGCCGCGGCGGCGGCGGCGGGAAGCAGCGGGGCTGGGGTTCCAGGGGGAGCGGCCGCCGCCTCAGCAGCCTCCTCGTCGTCCGCCTCG
TCTTCGTCTTCGTCATCGTCCTCAGCCTCTTCAGGGCCGGCCCTGCTCCGGGTGGGCCCGGGCTTCGACGCGGCGCTGCAGGTCTCGGCC
GCCATCGGCACCAACCTGCGCCGGTTCCGGGCCGTGTTTGGGGAGAGCGGCGGGGGAGGCGGCAGCGGAGAGGATGAGCAATTCTTAGGT
TTTGGCTCAGATGAAGAAGTCAGAGTGCGAAGTCCCACAAGGTCTCCTTCAGTTAAAACTAGTCCTCGAAAACCTCGTGGGAGACCTAGA
AGTGGCTCTGACCGAAATTCAGCTATCCTCTCAGATCCATCTGTGTTTTCCCCTCTAAATAAATCAGAGACCAAATCTGGAGATAAGATC
AAGAAGAAAGATTCTAAAAGTATAGAAAAGAAGAGAGGAAGACCTCCCACCTTCCCTGGAGTAAAAATCAAAATAACACATGGAAAGGAC
ATTTCAGAGTTACCAAAGGGAAACAAAGAAGATAGCCTGAAAAAAATTAAAAGGACACCTTCTGCTACGTTTCAGCAAGCCACAAAGATT
AAAAAATTAAGAGCAGGTAAACTCTCTCCTCTCAAGTCTAAGTTTAAGACAGGGAAGCTTCAAATAGGAAGGAAGGGGGTACAAATTGTA
CGACGGAGAGGAAGGCCTCCATCAACAGAAAGGATAAAGACCCCTTCGGGTCTCCTCATTAATTCTGAACTGGAAAAGCCCCAGAAAGTC
CGGAAAGACAAGGAAGGAACACCTCCACTTACAAAAGAAGATAAGACAGTTGTCAGACAAAGCCCTCGAAGGATTAAGCCAGTTAGGATT
ATTCCTTCTTCAAAAAGGACAGATGCAACCATTGCTAAGCAACTCTTACAGAGGGCAAAAAAGGGGGCTCAAAAGAAAATTGAAAAAGAA
GCAGCTCAGCTGCAGGGAAGAAAGGTGAAGACACAGGTCAAAAATATTCGACAGTTCATCATGCCTGTTGTCAGTGCTATCTCCTCGCGG
ATCATTAAGACCCCTCGGCGGTTTATAGAGGATGAGGATTATGACCCTCCAATTAAAATTGCCCGATTAGAGTCTACACCGAATAGTAGA
TTCAGTGCCCCGTCCTGTGGATCTTCTGAAAAATCAAGTGCAGCTTCTCAGCACTCCTCTCAAATGTCTTCAGACTCCTCTCGATCTAGT
AGCCCCAGTGTTGATACCTCCACAGACTCTCAGGCTTCTGAGGAGATTCAGGTACTTCCTGAGGAGCGGAGCGATACCCCTGAAGTTCAT
CCTCCACTGCCCATTTCCCAGTCCCCAGAAAATGAGAGTAATGATAGGAGAAGCAGAAGGTATTCAGTGTCGGAGAGAAGTTTTGGATCT
AGAACGACGAAAAAATTATCAACTCTACAAAGTGCCCCCCAGCAGCAGACCTCCTCGTCTCCACCTCCACCTCTGCTGACTCCACCGCCA
CCACTGCAGCCAGCCTCCAGTATCTCTGACCACACACCTTGGCTTATGCCTCCAACAATCCCCTTAGCATCACCATTTTTGCCTGCTTCC
ACTGCTCCTATGCAAGGGAAGCGAAAATCTATTTTGCGAGAACCGACATTTAGGTGGACTTCTTTAAAGCATTCTAGGTCAGAGCCACAA
TACTTTTCCTCAGCAAAGTATGCCAAAGAAGGTCTTATTCGCAAACCAATATTTGATAATTTCCGACCCCCTCCACTAACTCCCGAGGAC
GTTGGCTTTGCATCTGGTTTTTCTGCATCTGGTACCGCTGCTTCAGCCCGATTGTTTTCGCCACTCCATTCTGGAACAAGGTTTGATATG
CACAAAAGGAGCCCTCTTCTGAGAGCTCCAAGATTTACTCCAAGTGAGGCTCACTCTAGAATATTTGAGTCTGTAACCTTGCCTAGTAAT
CGAACTTCTGCTGGAACATCTTCTTCAGGAGTATCCAATAGAAAAAGGAAAAGAAAAGTGTTTAGTCCTATTCGATCTGAACCAAGATCT
CCTTCTCACTCCATGAGGACAAGAAGTGGAAGGCTTAGTAGTTCTGAGCTCTCACCTCTCACCCCCCCGTCTTCTGTCTCTTCCTCGTTA
AGCATTTCTGTTAGTCCTCTTGCCACTAGTGCCTTAAACCCAACTTTTACTTTTCCTTCTCATTCCCTGACTCAGTCTGGGGAATCTGCA
GAGAAAAATCAGAGACCAAGGAAGCAGACTAGTGCTCCGGCAGAGCCATTTTCATCAAGTAGTCCTACTCCTCTCTTCCCTTGGTTTACC
CCAGGCTCTCAGACTGAAAGAGGGAGAAATAAAGACAAGGCCCCCGAGGAGCTGTCCAAAGATCGAGATGCTGACAAGAGCGTGGAGAAG
GACAAGAGTAGAGAGAGAGACCGGGAGAGAGAAAAGGAGAATAAGCGGGAGTCAAGGAAAGAGAAAAGGAAAAAGGGATCAGAAATTCAG
AGTAGTTCTGCTTTGTATCCTGTGGGTAGGGTTTCCAAAGAGAAGGTTGTTGGTGAAGATGTTGCCACTTCATCTTCTGCCAAAAAAGCA
ACAGGGCGGAAGAAGTCTTCATCACATGATTCTGGGACTGATATTACTTCTGTGACTCTTGGGGATACAACAGCTGTCAAAACCAAAATA
CTTATAAAGAAAGGGAGAGGAAATCTGGAAAAAACCAACTTGGACCTCGGCCCAACTGCCCCATCCCTGGAGAAGGAGAAAACCCTCTGC
CTTTCCACTCCTTCATCTAGCACTGTTAAACATTCCACTTCCTCCATAGGCTCCATGTTGGCTCAGGCAGACAAGCTTCCAATGACTGAC
AAGAGGGTTGCCAGCCTCCTAAAAAAGGCCAAAGCTCAGCTCTGCAAGATTGAGAAGAGTAAGAGTCTTAAACAAACCGACCAGCCCAAA
GCACAGGGTCAAGAAAGTGACTCATCAGAGACCTCTGTGCGAGGACCCCGGATTAAACATGTCTGCAGAAGAGCAGCTGTTGCCCTTGGC
CGAAAACGAGCTGTGTTTCCTGATGACATGCCCACCCTGAGTGCCTTACCATGGGAAGAACGAGAAAAGATTTTGTCTTCCATGGGGAAT
GATGACAAGTCATCAATTGCTGGCTCAGAAGATGCTGAACCTCTTGCTCCACCCATCAAACCAATTAAACCTGTCACTAGAAACAAGGCA
CCCCAGGAACCTCCAGTAAAGAAAGGACGTCGATCGAGGCGGTGTGGGCAGTGTCCCGGCTGCCAGGTGCCTGAGGACTGTGGTGTTTGT
ACTAATTGCTTAGATAAGCCCAAGTTTGGTGGTCGCAATATAAAGAAGCAGTGCTGCAAGATGAGAAAATGTCAGAATCTACAATGGATG
CCTTCCAAAGCCTACCTGCAGAAGCAAGCTAAAGCTGTGAAAAAGAAAGAGAAAAAGTCTAAGACCAGTGAAAAGAAAGACAGCAAAGAG
AGCAGTGTTGTGAAGAACGTGGTGGACTCTAGTCAGAAACCTACCCCATCAGCAAGAGAGGATCCTGCCCCAAAGAAAAGCAGTAGTGAG
CCTCCTCCACGAAAGCCCGTCGAGGAAAAGAGTGAAGAAGGGAATGTCTCGGCCCCTGGGCCTGAATCCAAACAGGCCACCACTCCAGCT
TCCAGGAAGTCAAGCAAGCAGGTCTCCCAGCCAGCACTGGTCATCCCGCCTCAGCCACCTACTACAGGACCGCCAAGAAAAGAAGTTCCC
AAAACCACTCCTAGTGAGCCCAAGAAAAAGCAGCCTCCACCACCAGAATCAGGTCCAGAGCAGAGCAAACAGAAAAAAGTGGCTCCCCGC
CCAAGTATCCCTGTAAAACAAAAACCAAAAGAAAAGGAGATGACCTGGCTTCCACCACTTTCTGCTATTCAAGCACCTGGCAAAGTGGAA
CCAACCAAATTTCCATTTCCAAATAAGGACTCTCAGCTTGTATCCTCTGGACACAATAATCCAAAGAAAGGTGATGCAGAGCCAGAGAGT
CCAGACAGTGGCACATCGAATACATCAATGCTGGAAGATGACCTTAAGCTAAGCAGTGATGAAGAGGAGAATGAACAGCAGGCAGCTCAG
AGAACGGCTCTCCGCGCTCTCTCTGACAGCGCCGTGGTCCAGCAGCCCAACTGCAGAACCTCGGTGCCTTCCAGCAAGGGCAGCAGCAGC
AGCAGCAGCAGCGGCAGCAGCAGCTCCTCCAGCGACTCAGAGAGCAGCTCCGGATCTGACTCGGAGACCGAGAGCAGCTCCAGCGAGAGT
GAGGGCAGCAAGCCCCCCCACTTCTCCAGCCCCGAGGCTGAACCGGCATCCTCTAACAAGTGGCAGCTGGATAAATGGCTAAACAAAGTT
AATCCCCACAAGCCTCCTATTCTGATCCAAAATGAAAGCCACGGGTCAGAGAGCAATCAGTACTACAACCCGGTGAAAGAGGACGTCCAG
GACTGTGGGAAAGTCCCCGACGTTTGCCAGCCCAGCCTGAGAGAGAAGGAGATCAAGAGCACTTGCAAGGAGGAGCAAAGGCCAAGGACA
GCCAACAAGGCCCCTGGGAGTAAAGGCGTGAAGCAGAAGTCCCCGCCCGCGGCCGTGGCCGTGGCGGTGAGCGCAGCCGCCCCGCCACCC
GCAGTGCCCTGTGCGCCCGCGGAGAACGCGCCCGCGCCTGCCCGGAGGTCCGCGGGCAAGAAGCCCACCAGGCGCACCGAGAGGACCTCA
GCCGGGGACGGCGCCAACTGCCACCGGCCCGAGGAGCCCGCGGCCGCGGACGCGCTGGGGACGAGCGTGGTGGTCCCCCCGGAGCCCACC
AAAACCAGGCCCTGTGGCAACAACAGAGCGAGCCACCGCAAGGAGCTGCGCTCCTCCGTGACCTGCGAGAAGCGCCGCACGCGGGGGCTA
AGCAGGATCGTCCCCAAATCCAAGGAGTTCATTGAGACAGAGTCGTCATCTTCATCCTCCTCCTCGGACTCCGACCTGGAGTCCGAGCAG
GAGGAGTACCCTCTGTCCAAAGCACAGACCGTGGCTGCCTCTGCCTCCTCCGGGAATGATCAGAGGCTGAAGGAGGCCGCTGCCAACGGG
GGCAGTGGTCCTAGGGCCCCTGTAGGCTCCATCAACGCCAGGACCACCAGTGACATCGCCAAGGAGCTGGAGGAGCAGTTCTACACACTG
GTCCCCTTTGGCCGGAACGAACTTCTCTCCCCTCTAAAGGACAGTGATGAGATCAGGTCTCTCTGGGTCAAAATCGACCTGACCCTCCTG
TCCAGGATCCCAGAACACCTGCCCCAGGAGCCAGGGGTATTGAGCGCCCCTGCCACCAAGGACTCTGAGAGCGCACCGCCCAGCCACACC
TCGGACACACCTGCAGAAAAGGCTTTGCCAAAATCCAAGAGGAAACGCAAGTGTGACAACGAAGACGACTACAGGGAGATCAAGAAGTCC
CAGGGAGAGAAAGACAGCTCTTCAAGACTGGCCACCTCCACCAGTAATACTTTGTCTGCAAACCACTGCAACATGAACATCAACAGTGTG
GCAATACCAATAAATAAAAATGAAAAAATGCTTCGGTCGCCCATCTCACCCCTCTCTGATGCATCTAAACACAAATACACCAGCGAGGAC
TTAACTTCTTCCAGCCGACCTAATGGCAACAGTTTGTTTACTTCAGCCTCTTCCAGCAAAAAGCCTAAGGCCGACAGCCAGCTGCAGCCT
CACGGCGGAGACCTCACGAAAGCAGCTCACAACAATTCTGAAAACATTCCCCTCCACAAGTCACGGCCGCAGACGAAGCCGTGGTCTCCA
GGCTCCAACGGCCACAGGGACTGCAAGAGGCAGAAACTTGTCTTCGATGATATGCCTCGCAGTGCCGATTATTTTATGCAAGAAGCTAAA
CGAATGAAGCATAAAGCAGATGCAATGGTGGAAAAGTTTGGAAAGGCTTTGAACTATGCTGAAGCAGCATTGTCGTTTATCGAGTGTGGA
AATGCAATGGAACAAGGCCCCATGGAATCCAAATCTCCTTATACGATGTATTCAGAAACAGTAGAGCTCATCAGGTATGCTATGAGACTA
AAAACCCACTCAGGCCCCAATGCCACACCAGAAGACAAACAACTGGCTGCATTATGTTACCGATGCCTGGCCCTCCTGTACTGGCGGATG
TTTCGACTCAAAAGGGACCACGCTGTAAAGTATTCAAAAGCACTAATCGACTATTTCAAGAACTCATCTAAAGCCGCCCAAGCCCCATCT
CCGTGGGGGGCCAGTGGAAAGAGCACTGGAACCCCATCCCCCATGTCTCCCAACCCCTCTCCCGCCAGCTCCGTGGGGTCTCAGGGCAGC
CTCTCCAACGCCAGCGCCCTGTCCCCGTCGACCATCGTCAGCATCCCACAGCGCATCCACCAGATGGCGGCCAACCACGTCAGCATCACC
AACAGCATCCTGCACAGCTACGACTACTGGGAGATGGCCGACAACCTGGCCAAGGAAAACCGAGAATTCTTCAACGACCTGGATCTGCTC
ATGGGGCCGGTCACCCTGCACAGCAGCATGGAGCACCTGGTCCAGTACTCCCAACAGGGCCTGCACTGGCTGCGGAACAGCGCCCACCTG
TCATAGGGACCTCACCCTGGGGCCAGAGTGGGCTCTGGTCTCCACAGATGGCTCAACGTTTTTGGACACTGTGCTACTGAAACTCCCAGC
CACAGCATTTATCAGACTGCGGTGAACATTTCCTCAGCATTGAACAATGATCTTTTGCAGGGCATGTGTGTTTGTATGTGTGGGTATATA
AGAAGCCGCCTGTGTATGTGTGTAAGATACACAGCTCTTCAGAACACACCTTCTTTGTCTAGTTTCCATAATCCCAGGCTAGACAAAGTG
ATCAGAGGTTTCTGACTAGAGGAAGTACACACACACACACACACACACACACACACCGTACACTCACACACAATCACAGACACACACTTT
CTATTCCATTCCAGTGCTAAACCGTGACTTCTTAGAAAATTCAACCAAAATCTCATGGGTTAGTTAACCAGGTGCAATACAGCACACCAA
AAGCTTGACTGCCAGTGAAGATGGACCTGCTCTTATACTGTTGATTACTTTCAGTATTAATATACTATTCCCCAATTATTTTTTGATTGG
TATGTATTAATGGGTAATTGAATAATGAAAATAAGCCAGGTATTTTTGTGCCGGAAGTTTACTAGATTGCATGTTACCAAATACCCTGCT
CTTCCTCTAATTCCCTTCCCCCATCTGACTCTATTATCAACTAAATGCATTCCAGGCAAACAGATGGACACTCACAGCCCTTCCCAGCCC
CACCTCCAAGTAGTATGCAAATGGCACTGAGATTTAGCAAAAACGCGGCGTCTTTGAAAGTTAACAGACACTAAGGTAGCAGTGCCTGTG
TGTTGGAGCTCAGTTAGGAGTTGAAGTTTTCTGCACCTGTGATAACAAGCCCACCAGCCACATGCATTTCTTCTTCCTGCCACTGTGACT
CGGTGGCTGTAGAGCCACATGGCATTTGTCAGCCAATCTGTTTCAAGTCTTTTCTTTCCACCAATAGCTTTCTTACAGATTTTCTTGGCT
AAATGAGGCCATTACCTAGATTGTCCCTTCAGTAGGAGCCTGAATCCTTCGCTTACCAGGCTGAGAGCTATTTGCCATGATAATGCTGAT
TCTCTCACTCCTCATGCAGAATGTGCACCTGCAGCCCTTTGATGCGTTTTGATTTGGGGGCGATTTTTCAGGCTTTGATTAGCAGGCTGC
TTGCAATGCAGAAGATCACAGTTCCTTTCTGGGGCAGCAGCAACCAGAGCCTCTTCCTGTGTCCTGTGTGTCTGGTATGTTTACACCTTG
CTCTGAGTTTTTCTCTTGTTTTCTTTTTTTAATTAAGTTTACATTTTAGTTTCTTTGACATCTTGTTTACAGTTTTTGTCTGATGTTTTT
TCTTTTGTAGTGTCTTATGCCCTAGATTTAGTCATCTTGTTAAATATATTTGGATATGAAATCTTGACGAAAAGAAAATAACTCCTGAAA
AAGAGGGTCTATCTTGCCACACGTTAAAAACAAAAATAATGTCCTTGTGGCCTCTTACTTGATAAAGTTGCACCAGGACGGTCTGAGAAA
GGCAGGCGGTGTAATATGTGGTGCAATCCATTTTTTCAAGGTGATGACGGCACAAAATACTTAGACTAGATGCTGATCCATAAACATTCA
CTGATATTCTTACAGGTTGGTTTGCAGTGTTAACATTTTTGTTAGCCTGATCTGTAGGTGGGAAGTAAGATCATCATAATTCCTTAGCTC
TGAGCACTGATTCAAAATTGTATAAATGACTGAACAACTTAGATGATTTGAAATTAATTGAAAATAAGAAGGGCTTGTGGAATTTGCATT
TGGCTTTGGCCTTCAAGCATTTGGAAATATTAAGAGAATTTCCATTTTACATGTCTCCAACTGGGGTGCTTCTTACAACCCTTTCACTTT
TTTTTTGAGACGAGTTTCGCTCTGTTGCCCAGGCTGGAGTGCAGTGGCACGATCTCGGCTCACTGCATCCTCTGCCTCCTGGGTTCAAGT
GATTGTCCCGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGTGTGCACTACCATGCCCAGCTAATTTTTGTGTTTTTAGTAGAGACTGGG
TTTCACCATGTTGGCCAGGCTCGTCTCAAACTCCTGACCTCAGGTGATCTACCCGCCTCCACCTCCCAAAGTGTTGTGATTACAGGCGTG
AGCCACCACACCCAGCCCTTTCACTAATTTTTGGCAGAGTTCACAATCCCATCCTATGTCAGAAACTTGAACCTAACTTAAGAAATTTTG
AGTCATTTTTTTGGAGGACTGAGGCTTTGTTCTACCTACTCTTGAAGAATCCTGATGAAATATTCAAACACATAAAGGGATGGCCCTGGA
GGTCTATCCTGCATACCTGGAGAGCTTCTCTGGTCCTGCCCACCTTGAAAGTTGCAGACTTTGTTGTAACATCTATGTGATGAGCTTCCC
TGTGAAGCCCCATTTGACAGGTGGGCCAGCAGTGTTTTATCAGCACTCTGATGGCCCACATTTCCCAGGAAAACTTCTTGAAACTTACCG
TTGTGGGCAGTGGTCAGAGCGTGTAGTTCTTATGACTGTCTTGTTTCATCTGTGGAGCACGTGTGGAGCACGTTGGTACAGCAGTTTCTG
TGGGGTTTGGCATGGGTGATTTTGGTTAGTAACCATCCTCCAATTGTTGCTTGTGAAAGTCATTCATAACTTGTTCCTTTTACTTAGTTT
TGTTGTTACTGCTGTTGTTGTTGGTTTGGTTGGTTTTGAGACCGGGTCTGGCTCTGTAGCCCAAGCTGGAATGCGGTGGCGCGATCATGG
CTCCCTGCAGCCTCAAACTCCTGGGCTCAAGCAATCCTCCTGCCTCAGCCTCCCAAGCAGCTGGGAAGATAGGCACGTGCCACCACACCC
GGCTAATTTTTTCTTTATTTTTTTTGTAGAGATGGGGGTCTCACTATGTTGCCCAGGCTGGTCTCAAACTCCTGGGCTCAAGCGATCCTT
TGGCCTCGGCCTCCCAAAGTGCATGAGCCACCATGCCTGGCCTGTTTAGTTTTGTTTCAAGTTGAAATACCTTTCTTGTGTTTTCTAATT
AGAAAAGTAATATCTACTCATTGTAAAAACTCAAACAGTGCAGAAATGTAGAAAGTAGAAAGTGTAAGTCCCTGGTTGTCCCTTCTGCCT
GAGACAACCACTGCTCACAGTTTGATGTATATCCTTCCAGAGACTCTCAAATTTAAGCAAATAATTTTTATTACCATGTCTTTTTATTTG
AAGACGTACATTTGCCTCCAAAGTTCAACACAAGTTCAACTGACCATATCCTTCCATGACCTGAATAGATGCTATCCTTTATCACGATGT
TCAATTGCCTTTGAAAGAGAGTAGTCCAGGTATATTCCTGATCAAAATTTGGCATTTTTGATGATACTACTCTACACAGATCAGACTCAT
GTGCAGAATCGTGCCTGGAGAGAGAGGTTTGGTTAAGACAGAGATTTCTGGAAACATTCAAATTGCAAATGGAAACTTGAAACCCACAAT
CTAATGAGGAATGTACTGGAAAAATAATCTGAAGAGTTGACAAATTGTGTACTAGATTGAACACATGGAATGCAATGCAATGAGACTTTC
TGCACTAAAACTTATCCTCATATGTACAACAATGATGTGTGTATTATATAACAGTGATGTGTACATTTCTGACACCCCATACATAATATA
CACAGTTTGTATAAATGCATACATTTAAAAATATATATGTACAATACAGCTAACATAAAACTGTAGTACGCCTGAAGGATATTACTAGTG
CCTAATATTGAGTATGAGTCACTGCGTGTTCGCATCAACTTGGAAGTGCAGTAATTGTTATAAAATTAATCAGTGCAGCCAACATTATTT
ATGAATCACATCTTTGAAACTGTGCAGTAGCATATACATATATATTTTTAAATAACATTTTTCACAGTTTTCCAGAGTTACTGTTGAAAT
CTGCATCACCAAAAAAAAAAAAAAGCAAGATTTTTTTAACAATGTAGACACTCTTCAGACCCAGTAATCTGCGTGTGATTTCCTATTTGT
AGATTCCCAAGAGACTTTAGCAGTCACCAGCCTTAATGCATGTACAGGATATTATTGTGACTTAATTTATCTGCAGTTTTTAATCCATGT
GAAATTGGAATTTATAAACGGACTTGGATTAAACATGTCTGCCTTTCTAAGGTTGCAAATGTTACATTAAATGATTTATGTTGTAAATGA
GAGAAGTTGAGTTGTACGTAAAAGACATCCACCAATTTCTGTGAATATTTTTACACGGAAACTTGAGAATCAAAATACGTTCAAGTCAGT
TGTTCTGGCTCCCAGTTTATAATCTCGAAAAGCAATCTTTTTGTTTCATAAATGGCTTAAATGTAGCTCCCACAGATTATCAGTATGAAG
TCTGACATTTTTCATGGAAAAGAAGTATGTTTTTCTTCATTATAACTATAGTTTACTATTTGTCTTTGCTATTTCCTGATACATACACAT
ACGCACACACGCGCGCACATGCATGCACGTATGCACATGCACGCTCCCAGTGTCCCAGTGAAGGCTCAACAGGAAGCTTGAGAAGGTCAT
CTCAATGGCCACAGGGTTCCTGTTCAACCAGTAGCCCTGGGATGCCGCTTTGCTTGTCATTCTTTAGTGTCACAAGTTAGTTCCCTGACT
TGTGTGCAGTCAGGGAACTGCACACAACTGAAACCAACATGGTGGAATCATGTTTGCAATATTTGGTTGAGTAAAATAAGATAATTTTGA
ACTAAAGAAGACGGAGGCATTAGACCAGTGGCTTGACATGAAGCATCCCCTATGTGGGAGGGTAAGTTTGTTAACTTCATTTTTAGTCTT
ATCTCCAACCCTTTTCCTTATCCTCCTCCCCAAACTAAAGAAGCAGAAACAGCAACAAAAGCAAAACCATCCCTTCACCTGATCCAGCCC
ATGTCCTTAGATTCAAATATCCTTTGTCTTTTTCCCATTATACCATCTGACATAACTCACTCGTGTCTAGAGAGAAAAATGCAGAAAGGG
TTTGTTTGCAGATGGGCAGTTCAGTTGAGTCCTCATTAACCAGGCAGAGGGGTGCAGAAGAAGCCTGACTCAGGGTCACCATGGAGAACT
CCTCATCCCAGAGATGGGTGGGACAGGAACTTGGCTTTGCTTCACCAACCACTGAGCTTGATACTCTTTCAGAGGTGGTTTGTGCTAAGA
AACACCCAGCAGTCTTTCAAGAACGTTCTCTTCTGTAGCTTTGCCTGCTACACAGCTGAAGTCTGTCCCTATAAGAATTATATTTGTAAA
AAGTAATACATTTTCGAAGAAACCCGGATCAAGTGGAATCTTGAAAGTTTTTTTAATGAAAGGGGAAAAACAACCTGACCACATAAACTG
CACTTCCAACCATTTGGAACCAGAGTTTATGTCCTCATTTTCCCATTCTCAGAAGAGCACAGTTTTTCAATATTACAACTTCCTGGCAAA
TAGCACAAGAAATGTTCAGACTTGAGATTTGTGTTCCCTTTGTCCAGATTATTCTGTATATGTCACCAAAGGGGTTAACTTGTTTGCTTG

>In-frame_ENST00000354520_ENST00000409236_AF422798_KMT2A_chr11_118353211_+_AFF3_chr2_100368765_length(amino acids)=2281AA_start in transcript=0_stop in transcript=6845
MAHSCRWRFPARPGTTGGGGGGGRRGLGGAPRQRVPALLLPPGPPVGGGGPGAPPSPPAVAAAAAAAGSSGAGVPGGAAAASAASSSSAS
SSSSSSSSASSGPALLRVGPGFDAALQVSAAIGTNLRRFRAVFGESGGGGGSGEDEQFLGFGSDEEVRVRSPTRSPSVKTSPRKPRGRPR
SGSDRNSAILSDPSVFSPLNKSETKSGDKIKKKDSKSIEKKRGRPPTFPGVKIKITHGKDISELPKGNKEDSLKKIKRTPSATFQQATKI
KKLRAGKLSPLKSKFKTGKLQIGRKGVQIVRRRGRPPSTERIKTPSGLLINSELEKPQKVRKDKEGTPPLTKEDKTVVRQSPRRIKPVRI
IPSSKRTDATIAKQLLQRAKKGAQKKIEKEAAQLQGRKVKTQVKNIRQFIMPVVSAISSRIIKTPRRFIEDEDYDPPIKIARLESTPNSR
FSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGS
RTTKKLSTLQSAPQQQTSSSPPPPLLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQ
YFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSN
RTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESA
EKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQ
SSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKILIKKGRGNLEKTNLDLGPTAPSLEKEKTLC
LSTPSSSTVKHSTSSIGSMLAQADKLPMTDKRVASLLKKAKAQLCKIEKSKSLKQTDQPKAQGQESDSSETSVRGPRIKHVCRRAAVALG
RKRAVFPDDMPTLSALPWEEREKILSSMGNDDKSSIAGSEDAEPLAPPIKPIKPVTRNKAPQEPPVKKGRRSRRCGQCPGCQVPEDCGVC
TNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKSSSE
PPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPR
PSIPVKQKPKEKEMTWLPPLSAIQAPGKVEPTKFPFPNKDSQLVSSGHNNPKKGDAEPESPDSGTSNTSMLEDDLKLSSDEEENEQQAAQ
RTALRALSDSAVVQQPNCRTSVPSSKGSSSSSSSGSSSSSSDSESSSGSDSETESSSSESEGSKPPHFSSPEAEPASSNKWQLDKWLNKV
NPHKPPILIQNESHGSESNQYYNPVKEDVQDCGKVPDVCQPSLREKEIKSTCKEEQRPRTANKAPGSKGVKQKSPPAAVAVAVSAAAPPP
AVPCAPAENAPAPARRSAGKKPTRRTERTSAGDGANCHRPEEPAAADALGTSVVVPPEPTKTRPCGNNRASHRKELRSSVTCEKRRTRGL
SRIVPKSKEFIETESSSSSSSSDSDLESEQEEYPLSKAQTVAASASSGNDQRLKEAAANGGSGPRAPVGSINARTTSDIAKELEEQFYTL
VPFGRNELLSPLKDSDEIRSLWVKIDLTLLSRIPEHLPQEPGVLSAPATKDSESAPPSHTSDTPAEKALPKSKRKRKCDNEDDYREIKKS
QGEKDSSSRLATSTSNTLSANHCNMNINSVAIPINKNEKMLRSPISPLSDASKHKYTSEDLTSSSRPNGNSLFTSASSSKKPKADSQLQP
HGGDLTKAAHNNSENIPLHKSRPQTKPWSPGSNGHRDCKRQKLVFDDMPRSADYFMQEAKRMKHKADAMVEKFGKALNYAEAALSFIECG
NAMEQGPMESKSPYTMYSETVELIRYAMRLKTHSGPNATPEDKQLAALCYRCLALLYWRMFRLKRDHAVKYSKALIDYFKNSSKAAQAPS
PWGASGKSTGTPSPMSPNPSPASSVGSQGSLSNASALSPSTIVSIPQRIHQMAANHVSITNSILHSYDYWEMADNLAKENREFFNDLDLL

--------------------------------------------------------------
>In-frame_ENST00000354520_ENST00000356421_AF422798_KMT2A_chr11_118353211_+_AFF3_chr2_100368765_length(transcript)=11064nt_BP=4086nt
ATGGCGCACAGCTGTCGGTGGCGCTTCCCCGCCCGACCCGGGACCACCGGGGGCGGCGGCGGCGGGGGGCGCCGGGGCCTAGGGGGCGCC
CCGCGGCAACGCGTCCCGGCCCTGCTGCTTCCCCCCGGGCCCCCGGTCGGCGGTGGCGGCCCCGGGGCGCCCCCCTCCCCCCCGGCTGTG
GCGGCCGCGGCGGCGGCGGCGGGAAGCAGCGGGGCTGGGGTTCCAGGGGGAGCGGCCGCCGCCTCAGCAGCCTCCTCGTCGTCCGCCTCG
TCTTCGTCTTCGTCATCGTCCTCAGCCTCTTCAGGGCCGGCCCTGCTCCGGGTGGGCCCGGGCTTCGACGCGGCGCTGCAGGTCTCGGCC
GCCATCGGCACCAACCTGCGCCGGTTCCGGGCCGTGTTTGGGGAGAGCGGCGGGGGAGGCGGCAGCGGAGAGGATGAGCAATTCTTAGGT
TTTGGCTCAGATGAAGAAGTCAGAGTGCGAAGTCCCACAAGGTCTCCTTCAGTTAAAACTAGTCCTCGAAAACCTCGTGGGAGACCTAGA
AGTGGCTCTGACCGAAATTCAGCTATCCTCTCAGATCCATCTGTGTTTTCCCCTCTAAATAAATCAGAGACCAAATCTGGAGATAAGATC
AAGAAGAAAGATTCTAAAAGTATAGAAAAGAAGAGAGGAAGACCTCCCACCTTCCCTGGAGTAAAAATCAAAATAACACATGGAAAGGAC
ATTTCAGAGTTACCAAAGGGAAACAAAGAAGATAGCCTGAAAAAAATTAAAAGGACACCTTCTGCTACGTTTCAGCAAGCCACAAAGATT
AAAAAATTAAGAGCAGGTAAACTCTCTCCTCTCAAGTCTAAGTTTAAGACAGGGAAGCTTCAAATAGGAAGGAAGGGGGTACAAATTGTA
CGACGGAGAGGAAGGCCTCCATCAACAGAAAGGATAAAGACCCCTTCGGGTCTCCTCATTAATTCTGAACTGGAAAAGCCCCAGAAAGTC
CGGAAAGACAAGGAAGGAACACCTCCACTTACAAAAGAAGATAAGACAGTTGTCAGACAAAGCCCTCGAAGGATTAAGCCAGTTAGGATT
ATTCCTTCTTCAAAAAGGACAGATGCAACCATTGCTAAGCAACTCTTACAGAGGGCAAAAAAGGGGGCTCAAAAGAAAATTGAAAAAGAA
GCAGCTCAGCTGCAGGGAAGAAAGGTGAAGACACAGGTCAAAAATATTCGACAGTTCATCATGCCTGTTGTCAGTGCTATCTCCTCGCGG
ATCATTAAGACCCCTCGGCGGTTTATAGAGGATGAGGATTATGACCCTCCAATTAAAATTGCCCGATTAGAGTCTACACCGAATAGTAGA
TTCAGTGCCCCGTCCTGTGGATCTTCTGAAAAATCAAGTGCAGCTTCTCAGCACTCCTCTCAAATGTCTTCAGACTCCTCTCGATCTAGT
AGCCCCAGTGTTGATACCTCCACAGACTCTCAGGCTTCTGAGGAGATTCAGGTACTTCCTGAGGAGCGGAGCGATACCCCTGAAGTTCAT
CCTCCACTGCCCATTTCCCAGTCCCCAGAAAATGAGAGTAATGATAGGAGAAGCAGAAGGTATTCAGTGTCGGAGAGAAGTTTTGGATCT
AGAACGACGAAAAAATTATCAACTCTACAAAGTGCCCCCCAGCAGCAGACCTCCTCGTCTCCACCTCCACCTCTGCTGACTCCACCGCCA
CCACTGCAGCCAGCCTCCAGTATCTCTGACCACACACCTTGGCTTATGCCTCCAACAATCCCCTTAGCATCACCATTTTTGCCTGCTTCC
ACTGCTCCTATGCAAGGGAAGCGAAAATCTATTTTGCGAGAACCGACATTTAGGTGGACTTCTTTAAAGCATTCTAGGTCAGAGCCACAA
TACTTTTCCTCAGCAAAGTATGCCAAAGAAGGTCTTATTCGCAAACCAATATTTGATAATTTCCGACCCCCTCCACTAACTCCCGAGGAC
GTTGGCTTTGCATCTGGTTTTTCTGCATCTGGTACCGCTGCTTCAGCCCGATTGTTTTCGCCACTCCATTCTGGAACAAGGTTTGATATG
CACAAAAGGAGCCCTCTTCTGAGAGCTCCAAGATTTACTCCAAGTGAGGCTCACTCTAGAATATTTGAGTCTGTAACCTTGCCTAGTAAT
CGAACTTCTGCTGGAACATCTTCTTCAGGAGTATCCAATAGAAAAAGGAAAAGAAAAGTGTTTAGTCCTATTCGATCTGAACCAAGATCT
CCTTCTCACTCCATGAGGACAAGAAGTGGAAGGCTTAGTAGTTCTGAGCTCTCACCTCTCACCCCCCCGTCTTCTGTCTCTTCCTCGTTA
AGCATTTCTGTTAGTCCTCTTGCCACTAGTGCCTTAAACCCAACTTTTACTTTTCCTTCTCATTCCCTGACTCAGTCTGGGGAATCTGCA
GAGAAAAATCAGAGACCAAGGAAGCAGACTAGTGCTCCGGCAGAGCCATTTTCATCAAGTAGTCCTACTCCTCTCTTCCCTTGGTTTACC
CCAGGCTCTCAGACTGAAAGAGGGAGAAATAAAGACAAGGCCCCCGAGGAGCTGTCCAAAGATCGAGATGCTGACAAGAGCGTGGAGAAG
GACAAGAGTAGAGAGAGAGACCGGGAGAGAGAAAAGGAGAATAAGCGGGAGTCAAGGAAAGAGAAAAGGAAAAAGGGATCAGAAATTCAG
AGTAGTTCTGCTTTGTATCCTGTGGGTAGGGTTTCCAAAGAGAAGGTTGTTGGTGAAGATGTTGCCACTTCATCTTCTGCCAAAAAAGCA
ACAGGGCGGAAGAAGTCTTCATCACATGATTCTGGGACTGATATTACTTCTGTGACTCTTGGGGATACAACAGCTGTCAAAACCAAAATA
CTTATAAAGAAAGGGAGAGGAAATCTGGAAAAAACCAACTTGGACCTCGGCCCAACTGCCCCATCCCTGGAGAAGGAGAAAACCCTCTGC
CTTTCCACTCCTTCATCTAGCACTGTTAAACATTCCACTTCCTCCATAGGCTCCATGTTGGCTCAGGCAGACAAGCTTCCAATGACTGAC
AAGAGGGTTGCCAGCCTCCTAAAAAAGGCCAAAGCTCAGCTCTGCAAGATTGAGAAGAGTAAGAGTCTTAAACAAACCGACCAGCCCAAA
GCACAGGGTCAAGAAAGTGACTCATCAGAGACCTCTGTGCGAGGACCCCGGATTAAACATGTCTGCAGAAGAGCAGCTGTTGCCCTTGGC
CGAAAACGAGCTGTGTTTCCTGATGACATGCCCACCCTGAGTGCCTTACCATGGGAAGAACGAGAAAAGATTTTGTCTTCCATGGGGAAT
GATGACAAGTCATCAATTGCTGGCTCAGAAGATGCTGAACCTCTTGCTCCACCCATCAAACCAATTAAACCTGTCACTAGAAACAAGGCA
CCCCAGGAACCTCCAGTAAAGAAAGGACGTCGATCGAGGCGGTGTGGGCAGTGTCCCGGCTGCCAGGTGCCTGAGGACTGTGGTGTTTGT
ACTAATTGCTTAGATAAGCCCAAGTTTGGTGGTCGCAATATAAAGAAGCAGTGCTGCAAGATGAGAAAATGTCAGAATCTACAATGGATG
CCTTCCAAAGCCTACCTGCAGAAGCAAGCTAAAGCTGTGAAAAAGAAAGAGAAAAAGTCTAAGACCAGTGAAAAGAAAGACAGCAAAGAG
AGCAGTGTTGTGAAGAACGTGGTGGACTCTAGTCAGAAACCTACCCCATCAGCAAGAGAGGATCCTGCCCCAAAGAAAAGCAGTAGTGAG
CCTCCTCCACGAAAGCCCGTCGAGGAAAAGAGTGAAGAAGGGAATGTCTCGGCCCCTGGGCCTGAATCCAAACAGGCCACCACTCCAGCT
TCCAGGAAGTCAAGCAAGCAGGTCTCCCAGCCAGCACTGGTCATCCCGCCTCAGCCACCTACTACAGGACCGCCAAGAAAAGAAGTTCCC
AAAACCACTCCTAGTGAGCCCAAGAAAAAGCAGCCTCCACCACCAGAATCAGGTCCAGAGCAGAGCAAACAGAAAAAAGTGGCTCCCCGC
CCAAGTATCCCTGTAAAACAAAAACCAAAAGAAAAGGAGATGACCTGGCTTCCACCACTTTCTGCTATTCAAGCACCTGGCAAAGTGGAA
CCAACCAAATTTCCATTTCCAAATAAGGACTCTCAGCTTGTATCCTCTGGACACAATAATCCAAAGAAAGGTGATGCAGAGCCAGAGAGT
CCAGACAGTGGCACATCGAATACATCAATGCTGGAAGATGACCTTAAGCTAAGCAGTGATGAAGAGGAGAATGAACAGCAGGCAGCTCAG
AGAACGGCTCTCCGCGCTCTCTCTGACAGCGCCGTGGTCCAGCAGCCCAACTGCAGAACCTCGGTGCCTTCCAGCAAGGGCAGCAGCAGC
AGCAGCAGCAGCGGCAGCAGCAGCTCCTCCAGCGACTCAGAGAGCAGCTCCGGATCTGACTCGGAGACCGAGAGCAGCTCCAGCGAGAGT
GAGGGCAGCAAGCCCCCCCACTTCTCCAGCCCCGAGGCTGAACCGGCATCCTCTAACAAGTGGCAGCTGGATAAATGGCTAAACAAAGTT
AATCCCCACAAGCCTCCTATTCTGATCCAAAATGAAAGCCACGGGTCAGAGAGCAATCAGTACTACAACCCGGTGAAAGAGGACGTCCAG
GACTGTGGGAAAGTCCCCGACGTTTGCCAGCCCAGCCTGAGAGAGAAGGAGATCAAGAGCACTTGCAAGGAGGAGCAAAGGCCAAGGACA
GCCAACAAGGCCCCTGGGAGTAAAGGCGTGAAGCAGAAGTCCCCGCCCGCGGCCGTGGCCGTGGCGGTGAGCGCAGCCGCCCCGCCACCC
GCAGTGCCCTGTGCGCCCGCGGAGAACGCGCCCGCGCCTGCCCGGAGGTCCGCGGGCAAGAAGCCCACCAGGCGCACCGAGAGGACCTCA
GCCGGGGACGGCGCCAACTGCCACCGGCCCGAGGAGCCCGCGGCCGCGGACGCGCTGGGGACGAGCGTGGTGGTCCCCCCGGAGCCCACC
AAAACCAGGCCCTGTGGCAACAACAGAGCGAGCCACCGCAAGGAGCTGCGCTCCTCCGTGACCTGCGAGAAGCGCCGCACGCGGGGGCTA
AGCAGGATCGTCCCCAAATCCAAGGAGTTCATTGAGACAGAGTCGTCATCTTCATCCTCCTCCTCGGACTCCGACCTGGAGTCCGAGCAG
GAGGAGTACCCTCTGTCCAAAGCACAGACCGTGGCTGCCTCTGCCTCCTCCGGGAATGATCAGAGGCTGAAGGAGGCCGCTGCCAACGGG
GGCAGTGGTCCTAGGGCCCCTGTAGGCTCCATCAACGCCAGGACCACCAGTGACATCGCCAAGGAGCTGGAGGAGCAGTTCTACACACTG
GTCCCCTTTGGCCGGAACGAACTTCTCTCCCCTCTAAAGGACAGTGATGAGATCAGGTCTCTCTGGGTCAAAATCGACCTGACCCTCCTG
TCCAGGATCCCAGAACACCTGCCCCAGGAGCCAGGGGTATTGAGCGCCCCTGCCACCAAGGACTCTGAGAGCGCACCGCCCAGCCACACC
TCGGACACACCTGCAGAAAAGGCTTTGCCAAAATCCAAGAGGAAACGCAAGTGTGACAACGAAGACGACTACAGGGAGATCAAGAAGTCC
CAGGGAGAGAAAGACAGCTCTTCAAGACTGGCCACCTCCACCAGTAATACTTTGTCTGCAAACCACTGCAACATGAACATCAACAGTGTG
GCAATACCAATAAATAAAAATGAAAAAATGCTTCGGTCGCCCATCTCACCCCTCTCTGATGCATCTAAACACAAATACACCAGCGAGGAC
TTAACTTCTTCCAGCCGACCTAATGGCAACAGTTTGTTTACTTCAGCCTCTTCCAGCAAAAAGCCTAAGGCCGACAGCCAGCTGCAGCCT
CACGGCGGAGACCTCACGAAAGCAGCTCACAACAATTCTGAAAACATTCCCCTCCACAAGTCACGGCCGCAGACGAAGCCGTGGTCTCCA
GGCTCCAACGGCCACAGGGACTGCAAGAGGCAGAAACTTGTCTTCGATGATATGCCTCGCAGTGCCGATTATTTTATGCAAGAAGCTAAA
CGAATGAAGCATAAAGCAGATGCAATGGTGGAAAAGTTTGGAAAGGCTTTGAACTATGCTGAAGCAGCATTGTCGTTTATCGAGTGTGGA
AATGCAATGGAACAAGGCCCCATGGAATCCAAATCTCCTTATACGATGTATTCAGAAACAGTAGAGCTCATCAGGTATGCTATGAGACTA
AAAACCCACTCAGGCCCCAATGCCACACCAGAAGACAAACAACTGGCTGCATTATGTTACCGATGCCTGGCCCTCCTGTACTGGCGGATG
TTTCGACTCAAAAGGGACCACGCTGTAAAGTATTCAAAAGCACTAATCGACTATTTCAAGAACTCATCTAAAGCCGCCCAAGCCCCATCT
CCGTGGGGGGCCAGTGGAAAGAGCACTGGAACCCCATCCCCCATGTCTCCCAACCCCTCTCCCGCCAGCTCCGTGGGGTCTCAGGGCAGC
CTCTCCAACGCCAGCGCCCTGTCCCCGTCGACCATCGTCAGCATCCCACAGCGCATCCACCAGATGGCGGCCAACCACGTCAGCATCACC
AACAGCATCCTGCACAGCTACGACTACTGGGAGATGGCCGACAACCTGGCCAAGGAAAACCGAGAATTCTTCAACGACCTGGATCTGCTC
ATGGGGCCGGTCACCCTGCACAGCAGCATGGAGCACCTGGTCCAGTACTCCCAACAGGGCCTGCACTGGCTGCGGAACAGCGCCCACCTG
TCATAGGGACCTCACCCTGGGGCCAGAGTGGGCTCTGGTCTCCACAGATGGCTCAACGTTTTTGGACACTGTGCTACTGAAACTCCCAGC
CACAGCATTTATCAGACTGCGGTGAACATTTCCTCAGCATTGAACAATGATCTTTTGCAGGGCATGTGTGTTTGTATGTGTGGGTATATA
AGAAGCCGCCTGTGTATGTGTGTAAGATACACAGCTCTTCAGAACACACCTTCTTTGTCTAGTTTCCATAATCCCAGGCTAGACAAAGTG
ATCAGAGGTTTCTGACTAGAGGAAGTACACACACACACACACACACACACACACACCGTACACTCACACACAATCACAGACACACACTTT
CTATTCCATTCCAGTGCTAAACCGTGACTTCTTAGAAAATTCAACCAAAATCTCATGGGTTAGTTAACCAGGTGCAATACAGCACACCAA
AAGCTTGACTGCCAGTGAAGATGGACCTGCTCTTATACTGTTGATTACTTTCAGTATTAATATACTATTCCCCAATTATTTTTTGATTGG
TATGTATTAATGGGTAATTGAATAATGAAAATAAGCCAGGTATTTTTGTGCCGGAAGTTTACTAGATTGCATGTTACCAAATACCCTGCT
CTTCCTCTAATTCCCTTCCCCCATCTGACTCTATTATCAACTAAATGCATTCCAGGCAAACAGATGGACACTCACAGCCCTTCCCAGCCC
CACCTCCAAGTAGTATGCAAATGGCACTGAGATTTAGCAAAAACGCGGCGTCTTTGAAAGTTAACAGACACTAAGGTAGCAGTGCCTGTG
TGTTGGAGCTCAGTTAGGAGTTGAAGTTTTCTGCACCTGTGATAACAAGCCCACCAGCCACATGCATTTCTTCTTCCTGCCACTGTGACT
CGGTGGCTGTAGAGCCACATGGCATTTGTCAGCCAATCTGTTTCAAGTCTTTTCTTTCCACCAATAGCTTTCTTACAGATTTTCTTGGCT
AAATGAGGCCATTACCTAGATTGTCCCTTCAGTAGGAGCCTGAATCCTTCGCTTACCAGGCTGAGAGCTATTTGCCATGATAATGCTGAT
TCTCTCACTCCTCATGCAGAATGTGCACCTGCAGCCCTTTGATGCGTTTTGATTTGGGGGCGATTTTTCAGGCTTTGATTAGCAGGCTGC
TTGCAATGCAGAAGATCACAGTTCCTTTCTGGGGCAGCAGCAACCAGAGCCTCTTCCTGTGTCCTGTGTGTCTGGTATGTTTACACCTTG
CTCTGAGTTTTTCTCTTGTTTTCTTTTTTTAATTAAGTTTACATTTTAGTTTCTTTGACATCTTGTTTACAGTTTTTGTCTGATGTTTTT
TCTTTTGTAGTGTCTTATGCCCTAGATTTAGTCATCTTGTTAAATATATTTGGATATGAAATCTTGACGAAAAGAAAATAACTCCTGAAA
AAGAGGGTCTATCTTGCCACACGTTAAAAACAAAAATAATGTCCTTGTGGCCTCTTACTTGATAAAGTTGCACCAGGACGGTCTGAGAAA
GGCAGGCGGTGTAATATGTGGTGCAATCCATTTTTTCAAGGTGATGACGGCACAAAATACTTAGACTAGATGCTGATCCATAAACATTCA
CTGATATTCTTACAGGTTGGTTTGCAGTGTTAACATTTTTGTTAGCCTGATCTGTAGGTGGGAAGTAAGATCATCATAATTCCTTAGCTC
TGAGCACTGATTCAAAATTGTATAAATGACTGAACAACTTAGATGATTTGAAATTAATTGAAAATAAGAAGGGCTTGTGGAATTTGCATT
TGGCTTTGGCCTTCAAGCATTTGGAAATATTAAGAGAATTTCCATTTTACATGTCTCCAACTGGGGTGCTTCTTACAACCCTTTCACTTT
TTTTTTGAGACGAGTTTCGCTCTGTTGCCCAGGCTGGAGTGCAGTGGCACGATCTCGGCTCACTGCATCCTCTGCCTCCTGGGTTCAAGT
GATTGTCCCGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGTGTGCACTACCATGCCCAGCTAATTTTTGTGTTTTTAGTAGAGACTGGG
TTTCACCATGTTGGCCAGGCTCGTCTCAAACTCCTGACCTCAGGTGATCTACCCGCCTCCACCTCCCAAAGTGTTGTGATTACAGGCGTG
AGCCACCACACCCAGCCCTTTCACTAATTTTTGGCAGAGTTCACAATCCCATCCTATGTCAGAAACTTGAACCTAACTTAAGAAATTTTG
AGTCATTTTTTTGGAGGACTGAGGCTTTGTTCTACCTACTCTTGAAGAATCCTGATGAAATATTCAAACACATAAAGGGATGGCCCTGGA
GGTCTATCCTGCATACCTGGAGAGCTTCTCTGGTCCTGCCCACCTTGAAAGTTGCAGACTTTGTTGTAACATCTATGTGATGAGCTTCCC
TGTGAAGCCCCATTTGACAGGTGGGCCAGCAGTGTTTTATCAGCACTCTGATGGCCCACATTTCCCAGGAAAACTTCTTGAAACTTACCG
TTGTGGGCAGTGGTCAGAGCGTGTAGTTCTTATGACTGTCTTGTTTCATCTGTGGAGCACGTGTGGAGCACGTTGGTACAGCAGTTTCTG
TGGGGTTTGGCATGGGTGATTTTGGTTAGTAACCATCCTCCAATTGTTGCTTGTGAAAGTCATTCATAACTTGTTCCTTTTACTTAGTTT
TGTTGTTACTGCTGTTGTTGTTGGTTTGGTTGGTTTTGAGACCGGGTCTGGCTCTGTAGCCCAAGCTGGAATGCGGTGGCGCGATCATGG
CTCCCTGCAGCCTCAAACTCCTGGGCTCAAGCAATCCTCCTGCCTCAGCCTCCCAAGCAGCTGGGAAGATAGGCACGTGCCACCACACCC
GGCTAATTTTTTCTTTATTTTTTTTGTAGAGATGGGGGTCTCACTATGTTGCCCAGGCTGGTCTCAAACTCCTGGGCTCAAGCGATCCTT
TGGCCTCGGCCTCCCAAAGTGCATGAGCCACCATGCCTGGCCTGTTTAGTTTTGTTTCAAGTTGAAATACCTTTCTTGTGTTTTCTAATT
AGAAAAGTAATATCTACTCATTGTAAAAACTCAAACAGTGCAGAAATGTAGAAAGTAGAAAGTGTAAGTCCCTGGTTGTCCCTTCTGCCT
GAGACAACCACTGCTCACAGTTTGATGTATATCCTTCCAGAGACTCTCAAATTTAAGCAAATAATTTTTATTACCATGTCTTTTTATTTG
AAGACGTACATTTGCCTCCAAAGTTCAACACAAGTTCAACTGACCATATCCTTCCATGACCTGAATAGATGCTATCCTTTATCACGATGT
TCAATTGCCTTTGAAAGAGAGTAGTCCAGGTATATTCCTGATCAAAATTTGGCATTTTTGATGATACTACTCTACACAGATCAGACTCAT
GTGCAGAATCGTGCCTGGAGAGAGAGGTTTGGTTAAGACAGAGATTTCTGGAAACATTCAAATTGCAAATGGAAACTTGAAACCCACAAT
CTAATGAGGAATGTACTGGAAAAATAATCTGAAGAGTTGACAAATTGTGTACTAGATTGAACACATGGAATGCAATGCAATGAGACTTTC
TGCACTAAAACTTATCCTCATATGTACAACAATGATGTGTGTATTATATAACAGTGATGTGTACATTTCTGACACCCCATACATAATATA
CACAGTTTGTATAAATGCATACATTTAAAAATATATATGTACAATACAGCTAACATAAAACTGTAGTACGCCTGAAGGATATTACTAGTG
CCTAATATTGAGTATGAGTCACTGCGTGTTCGCATCAACTTGGAAGTGCAGTAATTGTTATAAAATTAATCAGTGCAGCCAACATTATTT
ATGAATCACATCTTTGAAACTGTGCAGTAGCATATACATATATATTTTTAAATAACATTTTTCACAGTTTTCCAGAGTTACTGTTGAAAT
CTGCATCACCAAAAAAAAAAAAAAGCAAGATTTTTTTAACAATGTAGACACTCTTCAGACCCAGTAATCTGCGTGTGATTTCCTATTTGT
AGATTCCCAAGAGACTTTAGCAGTCACCAGCCTTAATGCATGTACAGGATATTATTGTGACTTAATTTATCTGCAGTTTTTAATCCATGT

>In-frame_ENST00000354520_ENST00000356421_AF422798_KMT2A_chr11_118353211_+_AFF3_chr2_100368765_length(amino acids)=2281AA_start in transcript=0_stop in transcript=6845
MAHSCRWRFPARPGTTGGGGGGGRRGLGGAPRQRVPALLLPPGPPVGGGGPGAPPSPPAVAAAAAAAGSSGAGVPGGAAAASAASSSSAS
SSSSSSSSASSGPALLRVGPGFDAALQVSAAIGTNLRRFRAVFGESGGGGGSGEDEQFLGFGSDEEVRVRSPTRSPSVKTSPRKPRGRPR
SGSDRNSAILSDPSVFSPLNKSETKSGDKIKKKDSKSIEKKRGRPPTFPGVKIKITHGKDISELPKGNKEDSLKKIKRTPSATFQQATKI
KKLRAGKLSPLKSKFKTGKLQIGRKGVQIVRRRGRPPSTERIKTPSGLLINSELEKPQKVRKDKEGTPPLTKEDKTVVRQSPRRIKPVRI
IPSSKRTDATIAKQLLQRAKKGAQKKIEKEAAQLQGRKVKTQVKNIRQFIMPVVSAISSRIIKTPRRFIEDEDYDPPIKIARLESTPNSR
FSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGS
RTTKKLSTLQSAPQQQTSSSPPPPLLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQ
YFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSN
RTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESA
EKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQ
SSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKILIKKGRGNLEKTNLDLGPTAPSLEKEKTLC
LSTPSSSTVKHSTSSIGSMLAQADKLPMTDKRVASLLKKAKAQLCKIEKSKSLKQTDQPKAQGQESDSSETSVRGPRIKHVCRRAAVALG
RKRAVFPDDMPTLSALPWEEREKILSSMGNDDKSSIAGSEDAEPLAPPIKPIKPVTRNKAPQEPPVKKGRRSRRCGQCPGCQVPEDCGVC
TNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKSSSE
PPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPR
PSIPVKQKPKEKEMTWLPPLSAIQAPGKVEPTKFPFPNKDSQLVSSGHNNPKKGDAEPESPDSGTSNTSMLEDDLKLSSDEEENEQQAAQ
RTALRALSDSAVVQQPNCRTSVPSSKGSSSSSSSGSSSSSSDSESSSGSDSETESSSSESEGSKPPHFSSPEAEPASSNKWQLDKWLNKV
NPHKPPILIQNESHGSESNQYYNPVKEDVQDCGKVPDVCQPSLREKEIKSTCKEEQRPRTANKAPGSKGVKQKSPPAAVAVAVSAAAPPP
AVPCAPAENAPAPARRSAGKKPTRRTERTSAGDGANCHRPEEPAAADALGTSVVVPPEPTKTRPCGNNRASHRKELRSSVTCEKRRTRGL
SRIVPKSKEFIETESSSSSSSSDSDLESEQEEYPLSKAQTVAASASSGNDQRLKEAAANGGSGPRAPVGSINARTTSDIAKELEEQFYTL
VPFGRNELLSPLKDSDEIRSLWVKIDLTLLSRIPEHLPQEPGVLSAPATKDSESAPPSHTSDTPAEKALPKSKRKRKCDNEDDYREIKKS
QGEKDSSSRLATSTSNTLSANHCNMNINSVAIPINKNEKMLRSPISPLSDASKHKYTSEDLTSSSRPNGNSLFTSASSSKKPKADSQLQP
HGGDLTKAAHNNSENIPLHKSRPQTKPWSPGSNGHRDCKRQKLVFDDMPRSADYFMQEAKRMKHKADAMVEKFGKALNYAEAALSFIECG
NAMEQGPMESKSPYTMYSETVELIRYAMRLKTHSGPNATPEDKQLAALCYRCLALLYWRMFRLKRDHAVKYSKALIDYFKNSSKAAQAPS
PWGASGKSTGTPSPMSPNPSPASSVGSQGSLSNASALSPSTIVSIPQRIHQMAANHVSITNSILHSYDYWEMADNLAKENREFFNDLDLL

--------------------------------------------------------------
>In-frame_ENST00000354520_ENST00000317233_AF422798_KMT2A_chr11_118353211_+_AFF3_chr2_100368765_length(transcript)=11064nt_BP=4086nt
ATGGCGCACAGCTGTCGGTGGCGCTTCCCCGCCCGACCCGGGACCACCGGGGGCGGCGGCGGCGGGGGGCGCCGGGGCCTAGGGGGCGCC
CCGCGGCAACGCGTCCCGGCCCTGCTGCTTCCCCCCGGGCCCCCGGTCGGCGGTGGCGGCCCCGGGGCGCCCCCCTCCCCCCCGGCTGTG
GCGGCCGCGGCGGCGGCGGCGGGAAGCAGCGGGGCTGGGGTTCCAGGGGGAGCGGCCGCCGCCTCAGCAGCCTCCTCGTCGTCCGCCTCG
TCTTCGTCTTCGTCATCGTCCTCAGCCTCTTCAGGGCCGGCCCTGCTCCGGGTGGGCCCGGGCTTCGACGCGGCGCTGCAGGTCTCGGCC
GCCATCGGCACCAACCTGCGCCGGTTCCGGGCCGTGTTTGGGGAGAGCGGCGGGGGAGGCGGCAGCGGAGAGGATGAGCAATTCTTAGGT
TTTGGCTCAGATGAAGAAGTCAGAGTGCGAAGTCCCACAAGGTCTCCTTCAGTTAAAACTAGTCCTCGAAAACCTCGTGGGAGACCTAGA
AGTGGCTCTGACCGAAATTCAGCTATCCTCTCAGATCCATCTGTGTTTTCCCCTCTAAATAAATCAGAGACCAAATCTGGAGATAAGATC
AAGAAGAAAGATTCTAAAAGTATAGAAAAGAAGAGAGGAAGACCTCCCACCTTCCCTGGAGTAAAAATCAAAATAACACATGGAAAGGAC
ATTTCAGAGTTACCAAAGGGAAACAAAGAAGATAGCCTGAAAAAAATTAAAAGGACACCTTCTGCTACGTTTCAGCAAGCCACAAAGATT
AAAAAATTAAGAGCAGGTAAACTCTCTCCTCTCAAGTCTAAGTTTAAGACAGGGAAGCTTCAAATAGGAAGGAAGGGGGTACAAATTGTA
CGACGGAGAGGAAGGCCTCCATCAACAGAAAGGATAAAGACCCCTTCGGGTCTCCTCATTAATTCTGAACTGGAAAAGCCCCAGAAAGTC
CGGAAAGACAAGGAAGGAACACCTCCACTTACAAAAGAAGATAAGACAGTTGTCAGACAAAGCCCTCGAAGGATTAAGCCAGTTAGGATT
ATTCCTTCTTCAAAAAGGACAGATGCAACCATTGCTAAGCAACTCTTACAGAGGGCAAAAAAGGGGGCTCAAAAGAAAATTGAAAAAGAA
GCAGCTCAGCTGCAGGGAAGAAAGGTGAAGACACAGGTCAAAAATATTCGACAGTTCATCATGCCTGTTGTCAGTGCTATCTCCTCGCGG
ATCATTAAGACCCCTCGGCGGTTTATAGAGGATGAGGATTATGACCCTCCAATTAAAATTGCCCGATTAGAGTCTACACCGAATAGTAGA
TTCAGTGCCCCGTCCTGTGGATCTTCTGAAAAATCAAGTGCAGCTTCTCAGCACTCCTCTCAAATGTCTTCAGACTCCTCTCGATCTAGT
AGCCCCAGTGTTGATACCTCCACAGACTCTCAGGCTTCTGAGGAGATTCAGGTACTTCCTGAGGAGCGGAGCGATACCCCTGAAGTTCAT
CCTCCACTGCCCATTTCCCAGTCCCCAGAAAATGAGAGTAATGATAGGAGAAGCAGAAGGTATTCAGTGTCGGAGAGAAGTTTTGGATCT
AGAACGACGAAAAAATTATCAACTCTACAAAGTGCCCCCCAGCAGCAGACCTCCTCGTCTCCACCTCCACCTCTGCTGACTCCACCGCCA
CCACTGCAGCCAGCCTCCAGTATCTCTGACCACACACCTTGGCTTATGCCTCCAACAATCCCCTTAGCATCACCATTTTTGCCTGCTTCC
ACTGCTCCTATGCAAGGGAAGCGAAAATCTATTTTGCGAGAACCGACATTTAGGTGGACTTCTTTAAAGCATTCTAGGTCAGAGCCACAA
TACTTTTCCTCAGCAAAGTATGCCAAAGAAGGTCTTATTCGCAAACCAATATTTGATAATTTCCGACCCCCTCCACTAACTCCCGAGGAC
GTTGGCTTTGCATCTGGTTTTTCTGCATCTGGTACCGCTGCTTCAGCCCGATTGTTTTCGCCACTCCATTCTGGAACAAGGTTTGATATG
CACAAAAGGAGCCCTCTTCTGAGAGCTCCAAGATTTACTCCAAGTGAGGCTCACTCTAGAATATTTGAGTCTGTAACCTTGCCTAGTAAT
CGAACTTCTGCTGGAACATCTTCTTCAGGAGTATCCAATAGAAAAAGGAAAAGAAAAGTGTTTAGTCCTATTCGATCTGAACCAAGATCT
CCTTCTCACTCCATGAGGACAAGAAGTGGAAGGCTTAGTAGTTCTGAGCTCTCACCTCTCACCCCCCCGTCTTCTGTCTCTTCCTCGTTA
AGCATTTCTGTTAGTCCTCTTGCCACTAGTGCCTTAAACCCAACTTTTACTTTTCCTTCTCATTCCCTGACTCAGTCTGGGGAATCTGCA
GAGAAAAATCAGAGACCAAGGAAGCAGACTAGTGCTCCGGCAGAGCCATTTTCATCAAGTAGTCCTACTCCTCTCTTCCCTTGGTTTACC
CCAGGCTCTCAGACTGAAAGAGGGAGAAATAAAGACAAGGCCCCCGAGGAGCTGTCCAAAGATCGAGATGCTGACAAGAGCGTGGAGAAG
GACAAGAGTAGAGAGAGAGACCGGGAGAGAGAAAAGGAGAATAAGCGGGAGTCAAGGAAAGAGAAAAGGAAAAAGGGATCAGAAATTCAG
AGTAGTTCTGCTTTGTATCCTGTGGGTAGGGTTTCCAAAGAGAAGGTTGTTGGTGAAGATGTTGCCACTTCATCTTCTGCCAAAAAAGCA
ACAGGGCGGAAGAAGTCTTCATCACATGATTCTGGGACTGATATTACTTCTGTGACTCTTGGGGATACAACAGCTGTCAAAACCAAAATA
CTTATAAAGAAAGGGAGAGGAAATCTGGAAAAAACCAACTTGGACCTCGGCCCAACTGCCCCATCCCTGGAGAAGGAGAAAACCCTCTGC
CTTTCCACTCCTTCATCTAGCACTGTTAAACATTCCACTTCCTCCATAGGCTCCATGTTGGCTCAGGCAGACAAGCTTCCAATGACTGAC
AAGAGGGTTGCCAGCCTCCTAAAAAAGGCCAAAGCTCAGCTCTGCAAGATTGAGAAGAGTAAGAGTCTTAAACAAACCGACCAGCCCAAA
GCACAGGGTCAAGAAAGTGACTCATCAGAGACCTCTGTGCGAGGACCCCGGATTAAACATGTCTGCAGAAGAGCAGCTGTTGCCCTTGGC
CGAAAACGAGCTGTGTTTCCTGATGACATGCCCACCCTGAGTGCCTTACCATGGGAAGAACGAGAAAAGATTTTGTCTTCCATGGGGAAT
GATGACAAGTCATCAATTGCTGGCTCAGAAGATGCTGAACCTCTTGCTCCACCCATCAAACCAATTAAACCTGTCACTAGAAACAAGGCA
CCCCAGGAACCTCCAGTAAAGAAAGGACGTCGATCGAGGCGGTGTGGGCAGTGTCCCGGCTGCCAGGTGCCTGAGGACTGTGGTGTTTGT
ACTAATTGCTTAGATAAGCCCAAGTTTGGTGGTCGCAATATAAAGAAGCAGTGCTGCAAGATGAGAAAATGTCAGAATCTACAATGGATG
CCTTCCAAAGCCTACCTGCAGAAGCAAGCTAAAGCTGTGAAAAAGAAAGAGAAAAAGTCTAAGACCAGTGAAAAGAAAGACAGCAAAGAG
AGCAGTGTTGTGAAGAACGTGGTGGACTCTAGTCAGAAACCTACCCCATCAGCAAGAGAGGATCCTGCCCCAAAGAAAAGCAGTAGTGAG
CCTCCTCCACGAAAGCCCGTCGAGGAAAAGAGTGAAGAAGGGAATGTCTCGGCCCCTGGGCCTGAATCCAAACAGGCCACCACTCCAGCT
TCCAGGAAGTCAAGCAAGCAGGTCTCCCAGCCAGCACTGGTCATCCCGCCTCAGCCACCTACTACAGGACCGCCAAGAAAAGAAGTTCCC
AAAACCACTCCTAGTGAGCCCAAGAAAAAGCAGCCTCCACCACCAGAATCAGGTCCAGAGCAGAGCAAACAGAAAAAAGTGGCTCCCCGC
CCAAGTATCCCTGTAAAACAAAAACCAAAAGAAAAGGAGATGACCTGGCTTCCACCACTTTCTGCTATTCAAGCACCTGGCAAAGTGGAA
CCAACCAAATTTCCATTTCCAAATAAGGACTCTCAGCTTGTATCCTCTGGACACAATAATCCAAAGAAAGGTGATGCAGAGCCAGAGAGT
CCAGACAGTGGCACATCGAATACATCAATGCTGGAAGATGACCTTAAGCTAAGCAGTGATGAAGAGGAGAATGAACAGCAGGCAGCTCAG
AGAACGGCTCTCCGCGCTCTCTCTGACAGCGCCGTGGTCCAGCAGCCCAACTGCAGAACCTCGGTGCCTTCCAGCAAGGGCAGCAGCAGC
AGCAGCAGCAGCGGCAGCAGCAGCTCCTCCAGCGACTCAGAGAGCAGCTCCGGATCTGACTCGGAGACCGAGAGCAGCTCCAGCGAGAGT
GAGGGCAGCAAGCCCCCCCACTTCTCCAGCCCCGAGGCTGAACCGGCATCCTCTAACAAGTGGCAGCTGGATAAATGGCTAAACAAAGTT
AATCCCCACAAGCCTCCTATTCTGATCCAAAATGAAAGCCACGGGTCAGAGAGCAATCAGTACTACAACCCGGTGAAAGAGGACGTCCAG
GACTGTGGGAAAGTCCCCGACGTTTGCCAGCCCAGCCTGAGAGAGAAGGAGATCAAGAGCACTTGCAAGGAGGAGCAAAGGCCAAGGACA
GCCAACAAGGCCCCTGGGAGTAAAGGCGTGAAGCAGAAGTCCCCGCCCGCGGCCGTGGCCGTGGCGGTGAGCGCAGCCGCCCCGCCACCC
GCAGTGCCCTGTGCGCCCGCGGAGAACGCGCCCGCGCCTGCCCGGAGGTCCGCGGGCAAGAAGCCCACCAGGCGCACCGAGAGGACCTCA
GCCGGGGACGGCGCCAACTGCCACCGGCCCGAGGAGCCCGCGGCCGCGGACGCGCTGGGGACGAGCGTGGTGGTCCCCCCGGAGCCCACC
AAAACCAGGCCCTGTGGCAACAACAGAGCGAGCCACCGCAAGGAGCTGCGCTCCTCCGTGACCTGCGAGAAGCGCCGCACGCGGGGGCTA
AGCAGGATCGTCCCCAAATCCAAGGAGTTCATTGAGACAGAGTCGTCATCTTCATCCTCCTCCTCGGACTCCGACCTGGAGTCCGAGCAG
GAGGAGTACCCTCTGTCCAAAGCACAGACCGTGGCTGCCTCTGCCTCCTCCGGGAATGATCAGAGGCTGAAGGAGGCCGCTGCCAACGGG
GGCAGTGGTCCTAGGGCCCCTGTAGGCTCCATCAACGCCAGGACCACCAGTGACATCGCCAAGGAGCTGGAGGAGCAGTTCTACACACTG
GTCCCCTTTGGCCGGAACGAACTTCTCTCCCCTCTAAAGGACAGTGATGAGATCAGGTCTCTCTGGGTCAAAATCGACCTGACCCTCCTG
TCCAGGATCCCAGAACACCTGCCCCAGGAGCCAGGGGTATTGAGCGCCCCTGCCACCAAGGACTCTGAGAGCGCACCGCCCAGCCACACC
TCGGACACACCTGCAGAAAAGGCTTTGCCAAAATCCAAGAGGAAACGCAAGTGTGACAACGAAGACGACTACAGGGAGATCAAGAAGTCC
CAGGGAGAGAAAGACAGCTCTTCAAGACTGGCCACCTCCACCAGTAATACTTTGTCTGCAAACCACTGCAACATGAACATCAACAGTGTG
GCAATACCAATAAATAAAAATGAAAAAATGCTTCGGTCGCCCATCTCACCCCTCTCTGATGCATCTAAACACAAATACACCAGCGAGGAC
TTAACTTCTTCCAGCCGACCTAATGGCAACAGTTTGTTTACTTCAGCCTCTTCCAGCAAAAAGCCTAAGGCCGACAGCCAGCTGCAGCCT
CACGGCGGAGACCTCACGAAAGCAGCTCACAACAATTCTGAAAACATTCCCCTCCACAAGTCACGGCCGCAGACGAAGCCGTGGTCTCCA
GGCTCCAACGGCCACAGGGACTGCAAGAGGCAGAAACTTGTCTTCGATGATATGCCTCGCAGTGCCGATTATTTTATGCAAGAAGCTAAA
CGAATGAAGCATAAAGCAGATGCAATGGTGGAAAAGTTTGGAAAGGCTTTGAACTATGCTGAAGCAGCATTGTCGTTTATCGAGTGTGGA
AATGCAATGGAACAAGGCCCCATGGAATCCAAATCTCCTTATACGATGTATTCAGAAACAGTAGAGCTCATCAGGTATGCTATGAGACTA
AAAACCCACTCAGGCCCCAATGCCACACCAGAAGACAAACAACTGGCTGCATTATGTTACCGATGCCTGGCCCTCCTGTACTGGCGGATG
TTTCGACTCAAAAGGGACCACGCTGTAAAGTATTCAAAAGCACTAATCGACTATTTCAAGAACTCATCTAAAGCCGCCCAAGCCCCATCT
CCGTGGGGGGCCAGTGGAAAGAGCACTGGAACCCCATCCCCCATGTCTCCCAACCCCTCTCCCGCCAGCTCCGTGGGGTCTCAGGGCAGC
CTCTCCAACGCCAGCGCCCTGTCCCCGTCGACCATCGTCAGCATCCCACAGCGCATCCACCAGATGGCGGCCAACCACGTCAGCATCACC
AACAGCATCCTGCACAGCTACGACTACTGGGAGATGGCCGACAACCTGGCCAAGGAAAACCGAGAATTCTTCAACGACCTGGATCTGCTC
ATGGGGCCGGTCACCCTGCACAGCAGCATGGAGCACCTGGTCCAGTACTCCCAACAGGGCCTGCACTGGCTGCGGAACAGCGCCCACCTG
TCATAGGGACCTCACCCTGGGGCCAGAGTGGGCTCTGGTCTCCACAGATGGCTCAACGTTTTTGGACACTGTGCTACTGAAACTCCCAGC
CACAGCATTTATCAGACTGCGGTGAACATTTCCTCAGCATTGAACAATGATCTTTTGCAGGGCATGTGTGTTTGTATGTGTGGGTATATA
AGAAGCCGCCTGTGTATGTGTGTAAGATACACAGCTCTTCAGAACACACCTTCTTTGTCTAGTTTCCATAATCCCAGGCTAGACAAAGTG
ATCAGAGGTTTCTGACTAGAGGAAGTACACACACACACACACACACACACACACACCGTACACTCACACACAATCACAGACACACACTTT
CTATTCCATTCCAGTGCTAAACCGTGACTTCTTAGAAAATTCAACCAAAATCTCATGGGTTAGTTAACCAGGTGCAATACAGCACACCAA
AAGCTTGACTGCCAGTGAAGATGGACCTGCTCTTATACTGTTGATTACTTTCAGTATTAATATACTATTCCCCAATTATTTTTTGATTGG
TATGTATTAATGGGTAATTGAATAATGAAAATAAGCCAGGTATTTTTGTGCCGGAAGTTTACTAGATTGCATGTTACCAAATACCCTGCT
CTTCCTCTAATTCCCTTCCCCCATCTGACTCTATTATCAACTAAATGCATTCCAGGCAAACAGATGGACACTCACAGCCCTTCCCAGCCC
CACCTCCAAGTAGTATGCAAATGGCACTGAGATTTAGCAAAAACGCGGCGTCTTTGAAAGTTAACAGACACTAAGGTAGCAGTGCCTGTG
TGTTGGAGCTCAGTTAGGAGTTGAAGTTTTCTGCACCTGTGATAACAAGCCCACCAGCCACATGCATTTCTTCTTCCTGCCACTGTGACT
CGGTGGCTGTAGAGCCACATGGCATTTGTCAGCCAATCTGTTTCAAGTCTTTTCTTTCCACCAATAGCTTTCTTACAGATTTTCTTGGCT
AAATGAGGCCATTACCTAGATTGTCCCTTCAGTAGGAGCCTGAATCCTTCGCTTACCAGGCTGAGAGCTATTTGCCATGATAATGCTGAT
TCTCTCACTCCTCATGCAGAATGTGCACCTGCAGCCCTTTGATGCGTTTTGATTTGGGGGCGATTTTTCAGGCTTTGATTAGCAGGCTGC
TTGCAATGCAGAAGATCACAGTTCCTTTCTGGGGCAGCAGCAACCAGAGCCTCTTCCTGTGTCCTGTGTGTCTGGTATGTTTACACCTTG
CTCTGAGTTTTTCTCTTGTTTTCTTTTTTTAATTAAGTTTACATTTTAGTTTCTTTGACATCTTGTTTACAGTTTTTGTCTGATGTTTTT
TCTTTTGTAGTGTCTTATGCCCTAGATTTAGTCATCTTGTTAAATATATTTGGATATGAAATCTTGACGAAAAGAAAATAACTCCTGAAA
AAGAGGGTCTATCTTGCCACACGTTAAAAACAAAAATAATGTCCTTGTGGCCTCTTACTTGATAAAGTTGCACCAGGACGGTCTGAGAAA
GGCAGGCGGTGTAATATGTGGTGCAATCCATTTTTTCAAGGTGATGACGGCACAAAATACTTAGACTAGATGCTGATCCATAAACATTCA
CTGATATTCTTACAGGTTGGTTTGCAGTGTTAACATTTTTGTTAGCCTGATCTGTAGGTGGGAAGTAAGATCATCATAATTCCTTAGCTC
TGAGCACTGATTCAAAATTGTATAAATGACTGAACAACTTAGATGATTTGAAATTAATTGAAAATAAGAAGGGCTTGTGGAATTTGCATT
TGGCTTTGGCCTTCAAGCATTTGGAAATATTAAGAGAATTTCCATTTTACATGTCTCCAACTGGGGTGCTTCTTACAACCCTTTCACTTT
TTTTTTGAGACGAGTTTCGCTCTGTTGCCCAGGCTGGAGTGCAGTGGCACGATCTCGGCTCACTGCATCCTCTGCCTCCTGGGTTCAAGT
GATTGTCCCGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGTGTGCACTACCATGCCCAGCTAATTTTTGTGTTTTTAGTAGAGACTGGG
TTTCACCATGTTGGCCAGGCTCGTCTCAAACTCCTGACCTCAGGTGATCTACCCGCCTCCACCTCCCAAAGTGTTGTGATTACAGGCGTG
AGCCACCACACCCAGCCCTTTCACTAATTTTTGGCAGAGTTCACAATCCCATCCTATGTCAGAAACTTGAACCTAACTTAAGAAATTTTG
AGTCATTTTTTTGGAGGACTGAGGCTTTGTTCTACCTACTCTTGAAGAATCCTGATGAAATATTCAAACACATAAAGGGATGGCCCTGGA
GGTCTATCCTGCATACCTGGAGAGCTTCTCTGGTCCTGCCCACCTTGAAAGTTGCAGACTTTGTTGTAACATCTATGTGATGAGCTTCCC
TGTGAAGCCCCATTTGACAGGTGGGCCAGCAGTGTTTTATCAGCACTCTGATGGCCCACATTTCCCAGGAAAACTTCTTGAAACTTACCG
TTGTGGGCAGTGGTCAGAGCGTGTAGTTCTTATGACTGTCTTGTTTCATCTGTGGAGCACGTGTGGAGCACGTTGGTACAGCAGTTTCTG
TGGGGTTTGGCATGGGTGATTTTGGTTAGTAACCATCCTCCAATTGTTGCTTGTGAAAGTCATTCATAACTTGTTCCTTTTACTTAGTTT
TGTTGTTACTGCTGTTGTTGTTGGTTTGGTTGGTTTTGAGACCGGGTCTGGCTCTGTAGCCCAAGCTGGAATGCGGTGGCGCGATCATGG
CTCCCTGCAGCCTCAAACTCCTGGGCTCAAGCAATCCTCCTGCCTCAGCCTCCCAAGCAGCTGGGAAGATAGGCACGTGCCACCACACCC
GGCTAATTTTTTCTTTATTTTTTTTGTAGAGATGGGGGTCTCACTATGTTGCCCAGGCTGGTCTCAAACTCCTGGGCTCAAGCGATCCTT
TGGCCTCGGCCTCCCAAAGTGCATGAGCCACCATGCCTGGCCTGTTTAGTTTTGTTTCAAGTTGAAATACCTTTCTTGTGTTTTCTAATT
AGAAAAGTAATATCTACTCATTGTAAAAACTCAAACAGTGCAGAAATGTAGAAAGTAGAAAGTGTAAGTCCCTGGTTGTCCCTTCTGCCT
GAGACAACCACTGCTCACAGTTTGATGTATATCCTTCCAGAGACTCTCAAATTTAAGCAAATAATTTTTATTACCATGTCTTTTTATTTG
AAGACGTACATTTGCCTCCAAAGTTCAACACAAGTTCAACTGACCATATCCTTCCATGACCTGAATAGATGCTATCCTTTATCACGATGT
TCAATTGCCTTTGAAAGAGAGTAGTCCAGGTATATTCCTGATCAAAATTTGGCATTTTTGATGATACTACTCTACACAGATCAGACTCAT
GTGCAGAATCGTGCCTGGAGAGAGAGGTTTGGTTAAGACAGAGATTTCTGGAAACATTCAAATTGCAAATGGAAACTTGAAACCCACAAT
CTAATGAGGAATGTACTGGAAAAATAATCTGAAGAGTTGACAAATTGTGTACTAGATTGAACACATGGAATGCAATGCAATGAGACTTTC
TGCACTAAAACTTATCCTCATATGTACAACAATGATGTGTGTATTATATAACAGTGATGTGTACATTTCTGACACCCCATACATAATATA
CACAGTTTGTATAAATGCATACATTTAAAAATATATATGTACAATACAGCTAACATAAAACTGTAGTACGCCTGAAGGATATTACTAGTG
CCTAATATTGAGTATGAGTCACTGCGTGTTCGCATCAACTTGGAAGTGCAGTAATTGTTATAAAATTAATCAGTGCAGCCAACATTATTT
ATGAATCACATCTTTGAAACTGTGCAGTAGCATATACATATATATTTTTAAATAACATTTTTCACAGTTTTCCAGAGTTACTGTTGAAAT
CTGCATCACCAAAAAAAAAAAAAAGCAAGATTTTTTTAACAATGTAGACACTCTTCAGACCCAGTAATCTGCGTGTGATTTCCTATTTGT
AGATTCCCAAGAGACTTTAGCAGTCACCAGCCTTAATGCATGTACAGGATATTATTGTGACTTAATTTATCTGCAGTTTTTAATCCATGT

>In-frame_ENST00000354520_ENST00000317233_AF422798_KMT2A_chr11_118353211_+_AFF3_chr2_100368765_length(amino acids)=2281AA_start in transcript=0_stop in transcript=6845
MAHSCRWRFPARPGTTGGGGGGGRRGLGGAPRQRVPALLLPPGPPVGGGGPGAPPSPPAVAAAAAAAGSSGAGVPGGAAAASAASSSSAS
SSSSSSSSASSGPALLRVGPGFDAALQVSAAIGTNLRRFRAVFGESGGGGGSGEDEQFLGFGSDEEVRVRSPTRSPSVKTSPRKPRGRPR
SGSDRNSAILSDPSVFSPLNKSETKSGDKIKKKDSKSIEKKRGRPPTFPGVKIKITHGKDISELPKGNKEDSLKKIKRTPSATFQQATKI
KKLRAGKLSPLKSKFKTGKLQIGRKGVQIVRRRGRPPSTERIKTPSGLLINSELEKPQKVRKDKEGTPPLTKEDKTVVRQSPRRIKPVRI
IPSSKRTDATIAKQLLQRAKKGAQKKIEKEAAQLQGRKVKTQVKNIRQFIMPVVSAISSRIIKTPRRFIEDEDYDPPIKIARLESTPNSR
FSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGS
RTTKKLSTLQSAPQQQTSSSPPPPLLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQ
YFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSN
RTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESA
EKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQ
SSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKILIKKGRGNLEKTNLDLGPTAPSLEKEKTLC
LSTPSSSTVKHSTSSIGSMLAQADKLPMTDKRVASLLKKAKAQLCKIEKSKSLKQTDQPKAQGQESDSSETSVRGPRIKHVCRRAAVALG
RKRAVFPDDMPTLSALPWEEREKILSSMGNDDKSSIAGSEDAEPLAPPIKPIKPVTRNKAPQEPPVKKGRRSRRCGQCPGCQVPEDCGVC
TNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKSSSE
PPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPR
PSIPVKQKPKEKEMTWLPPLSAIQAPGKVEPTKFPFPNKDSQLVSSGHNNPKKGDAEPESPDSGTSNTSMLEDDLKLSSDEEENEQQAAQ
RTALRALSDSAVVQQPNCRTSVPSSKGSSSSSSSGSSSSSSDSESSSGSDSETESSSSESEGSKPPHFSSPEAEPASSNKWQLDKWLNKV
NPHKPPILIQNESHGSESNQYYNPVKEDVQDCGKVPDVCQPSLREKEIKSTCKEEQRPRTANKAPGSKGVKQKSPPAAVAVAVSAAAPPP
AVPCAPAENAPAPARRSAGKKPTRRTERTSAGDGANCHRPEEPAAADALGTSVVVPPEPTKTRPCGNNRASHRKELRSSVTCEKRRTRGL
SRIVPKSKEFIETESSSSSSSSDSDLESEQEEYPLSKAQTVAASASSGNDQRLKEAAANGGSGPRAPVGSINARTTSDIAKELEEQFYTL
VPFGRNELLSPLKDSDEIRSLWVKIDLTLLSRIPEHLPQEPGVLSAPATKDSESAPPSHTSDTPAEKALPKSKRKRKCDNEDDYREIKKS
QGEKDSSSRLATSTSNTLSANHCNMNINSVAIPINKNEKMLRSPISPLSDASKHKYTSEDLTSSSRPNGNSLFTSASSSKKPKADSQLQP
HGGDLTKAAHNNSENIPLHKSRPQTKPWSPGSNGHRDCKRQKLVFDDMPRSADYFMQEAKRMKHKADAMVEKFGKALNYAEAALSFIECG
NAMEQGPMESKSPYTMYSETVELIRYAMRLKTHSGPNATPEDKQLAALCYRCLALLYWRMFRLKRDHAVKYSKALIDYFKNSSKAAQAPS
PWGASGKSTGTPSPMSPNPSPASSVGSQGSLSNASALSPSTIVSIPQRIHQMAANHVSITNSILHSYDYWEMADNLAKENREFFNDLDLL

--------------------------------------------------------------
>In-frame_ENST00000354520_ENST00000409579_AF422798_KMT2A_chr11_118353211_+_AFF3_chr2_100368765_length(transcript)=7199nt_BP=4086nt
ATGGCGCACAGCTGTCGGTGGCGCTTCCCCGCCCGACCCGGGACCACCGGGGGCGGCGGCGGCGGGGGGCGCCGGGGCCTAGGGGGCGCC
CCGCGGCAACGCGTCCCGGCCCTGCTGCTTCCCCCCGGGCCCCCGGTCGGCGGTGGCGGCCCCGGGGCGCCCCCCTCCCCCCCGGCTGTG
GCGGCCGCGGCGGCGGCGGCGGGAAGCAGCGGGGCTGGGGTTCCAGGGGGAGCGGCCGCCGCCTCAGCAGCCTCCTCGTCGTCCGCCTCG
TCTTCGTCTTCGTCATCGTCCTCAGCCTCTTCAGGGCCGGCCCTGCTCCGGGTGGGCCCGGGCTTCGACGCGGCGCTGCAGGTCTCGGCC
GCCATCGGCACCAACCTGCGCCGGTTCCGGGCCGTGTTTGGGGAGAGCGGCGGGGGAGGCGGCAGCGGAGAGGATGAGCAATTCTTAGGT
TTTGGCTCAGATGAAGAAGTCAGAGTGCGAAGTCCCACAAGGTCTCCTTCAGTTAAAACTAGTCCTCGAAAACCTCGTGGGAGACCTAGA
AGTGGCTCTGACCGAAATTCAGCTATCCTCTCAGATCCATCTGTGTTTTCCCCTCTAAATAAATCAGAGACCAAATCTGGAGATAAGATC
AAGAAGAAAGATTCTAAAAGTATAGAAAAGAAGAGAGGAAGACCTCCCACCTTCCCTGGAGTAAAAATCAAAATAACACATGGAAAGGAC
ATTTCAGAGTTACCAAAGGGAAACAAAGAAGATAGCCTGAAAAAAATTAAAAGGACACCTTCTGCTACGTTTCAGCAAGCCACAAAGATT
AAAAAATTAAGAGCAGGTAAACTCTCTCCTCTCAAGTCTAAGTTTAAGACAGGGAAGCTTCAAATAGGAAGGAAGGGGGTACAAATTGTA
CGACGGAGAGGAAGGCCTCCATCAACAGAAAGGATAAAGACCCCTTCGGGTCTCCTCATTAATTCTGAACTGGAAAAGCCCCAGAAAGTC
CGGAAAGACAAGGAAGGAACACCTCCACTTACAAAAGAAGATAAGACAGTTGTCAGACAAAGCCCTCGAAGGATTAAGCCAGTTAGGATT
ATTCCTTCTTCAAAAAGGACAGATGCAACCATTGCTAAGCAACTCTTACAGAGGGCAAAAAAGGGGGCTCAAAAGAAAATTGAAAAAGAA
GCAGCTCAGCTGCAGGGAAGAAAGGTGAAGACACAGGTCAAAAATATTCGACAGTTCATCATGCCTGTTGTCAGTGCTATCTCCTCGCGG
ATCATTAAGACCCCTCGGCGGTTTATAGAGGATGAGGATTATGACCCTCCAATTAAAATTGCCCGATTAGAGTCTACACCGAATAGTAGA
TTCAGTGCCCCGTCCTGTGGATCTTCTGAAAAATCAAGTGCAGCTTCTCAGCACTCCTCTCAAATGTCTTCAGACTCCTCTCGATCTAGT
AGCCCCAGTGTTGATACCTCCACAGACTCTCAGGCTTCTGAGGAGATTCAGGTACTTCCTGAGGAGCGGAGCGATACCCCTGAAGTTCAT
CCTCCACTGCCCATTTCCCAGTCCCCAGAAAATGAGAGTAATGATAGGAGAAGCAGAAGGTATTCAGTGTCGGAGAGAAGTTTTGGATCT
AGAACGACGAAAAAATTATCAACTCTACAAAGTGCCCCCCAGCAGCAGACCTCCTCGTCTCCACCTCCACCTCTGCTGACTCCACCGCCA
CCACTGCAGCCAGCCTCCAGTATCTCTGACCACACACCTTGGCTTATGCCTCCAACAATCCCCTTAGCATCACCATTTTTGCCTGCTTCC
ACTGCTCCTATGCAAGGGAAGCGAAAATCTATTTTGCGAGAACCGACATTTAGGTGGACTTCTTTAAAGCATTCTAGGTCAGAGCCACAA
TACTTTTCCTCAGCAAAGTATGCCAAAGAAGGTCTTATTCGCAAACCAATATTTGATAATTTCCGACCCCCTCCACTAACTCCCGAGGAC
GTTGGCTTTGCATCTGGTTTTTCTGCATCTGGTACCGCTGCTTCAGCCCGATTGTTTTCGCCACTCCATTCTGGAACAAGGTTTGATATG
CACAAAAGGAGCCCTCTTCTGAGAGCTCCAAGATTTACTCCAAGTGAGGCTCACTCTAGAATATTTGAGTCTGTAACCTTGCCTAGTAAT
CGAACTTCTGCTGGAACATCTTCTTCAGGAGTATCCAATAGAAAAAGGAAAAGAAAAGTGTTTAGTCCTATTCGATCTGAACCAAGATCT
CCTTCTCACTCCATGAGGACAAGAAGTGGAAGGCTTAGTAGTTCTGAGCTCTCACCTCTCACCCCCCCGTCTTCTGTCTCTTCCTCGTTA
AGCATTTCTGTTAGTCCTCTTGCCACTAGTGCCTTAAACCCAACTTTTACTTTTCCTTCTCATTCCCTGACTCAGTCTGGGGAATCTGCA
GAGAAAAATCAGAGACCAAGGAAGCAGACTAGTGCTCCGGCAGAGCCATTTTCATCAAGTAGTCCTACTCCTCTCTTCCCTTGGTTTACC
CCAGGCTCTCAGACTGAAAGAGGGAGAAATAAAGACAAGGCCCCCGAGGAGCTGTCCAAAGATCGAGATGCTGACAAGAGCGTGGAGAAG
GACAAGAGTAGAGAGAGAGACCGGGAGAGAGAAAAGGAGAATAAGCGGGAGTCAAGGAAAGAGAAAAGGAAAAAGGGATCAGAAATTCAG
AGTAGTTCTGCTTTGTATCCTGTGGGTAGGGTTTCCAAAGAGAAGGTTGTTGGTGAAGATGTTGCCACTTCATCTTCTGCCAAAAAAGCA
ACAGGGCGGAAGAAGTCTTCATCACATGATTCTGGGACTGATATTACTTCTGTGACTCTTGGGGATACAACAGCTGTCAAAACCAAAATA
CTTATAAAGAAAGGGAGAGGAAATCTGGAAAAAACCAACTTGGACCTCGGCCCAACTGCCCCATCCCTGGAGAAGGAGAAAACCCTCTGC
CTTTCCACTCCTTCATCTAGCACTGTTAAACATTCCACTTCCTCCATAGGCTCCATGTTGGCTCAGGCAGACAAGCTTCCAATGACTGAC
AAGAGGGTTGCCAGCCTCCTAAAAAAGGCCAAAGCTCAGCTCTGCAAGATTGAGAAGAGTAAGAGTCTTAAACAAACCGACCAGCCCAAA
GCACAGGGTCAAGAAAGTGACTCATCAGAGACCTCTGTGCGAGGACCCCGGATTAAACATGTCTGCAGAAGAGCAGCTGTTGCCCTTGGC
CGAAAACGAGCTGTGTTTCCTGATGACATGCCCACCCTGAGTGCCTTACCATGGGAAGAACGAGAAAAGATTTTGTCTTCCATGGGGAAT
GATGACAAGTCATCAATTGCTGGCTCAGAAGATGCTGAACCTCTTGCTCCACCCATCAAACCAATTAAACCTGTCACTAGAAACAAGGCA
CCCCAGGAACCTCCAGTAAAGAAAGGACGTCGATCGAGGCGGTGTGGGCAGTGTCCCGGCTGCCAGGTGCCTGAGGACTGTGGTGTTTGT
ACTAATTGCTTAGATAAGCCCAAGTTTGGTGGTCGCAATATAAAGAAGCAGTGCTGCAAGATGAGAAAATGTCAGAATCTACAATGGATG
CCTTCCAAAGCCTACCTGCAGAAGCAAGCTAAAGCTGTGAAAAAGAAAGAGAAAAAGTCTAAGACCAGTGAAAAGAAAGACAGCAAAGAG
AGCAGTGTTGTGAAGAACGTGGTGGACTCTAGTCAGAAACCTACCCCATCAGCAAGAGAGGATCCTGCCCCAAAGAAAAGCAGTAGTGAG
CCTCCTCCACGAAAGCCCGTCGAGGAAAAGAGTGAAGAAGGGAATGTCTCGGCCCCTGGGCCTGAATCCAAACAGGCCACCACTCCAGCT
TCCAGGAAGTCAAGCAAGCAGGTCTCCCAGCCAGCACTGGTCATCCCGCCTCAGCCACCTACTACAGGACCGCCAAGAAAAGAAGTTCCC
AAAACCACTCCTAGTGAGCCCAAGAAAAAGCAGCCTCCACCACCAGAATCAGGTCCAGAGCAGAGCAAACAGAAAAAAGTGGCTCCCCGC
CCAAGTATCCCTGTAAAACAAAAACCAAAAGAAAAGGAGATGACCTGGCTTCCACCACTTTCTGCTATTCAAGCACCTGGCAAAGTGGAA
CCAACCAAATTTCCATTTCCAAATAAGGACTCTCAGCTTGTATCCTCTGGACACAATAATCCAAAGAAAGGTGATGCAGAGCCAGAGAGT
CCAGACAGTGGCACATCGAATACATCAATGCTGGAAGATGACCTTAAGCTAAGCAGTGATGAAGAGGAGAATGAACAGCAGGCAGCTCAG
AGAACGGCTCTCCGCGCTCTCTCTGACAGCGCCGTGGTCCAGCAGCCCAACTGCAGAACCTCGGTGCCTTCCAGCAAGGGCAGCAGCAGC
AGCAGCAGCAGCGGCAGCAGCAGCTCCTCCAGCGACTCAGAGAGCAGCTCCGGATCTGACTCGGAGACCGAGAGCAGCTCCAGCGAGAGT
GAGGGCAGCAAGCCCCCCCACTTCTCCAGCCCCGAGGCTGAACCGGCATCCTCTAACAAGTGGCAGCTGGATAAATGGCTAAACAAAGTT
AATCCCCACAAGCCTCCTATTCTGATCCAAAATGAAAGCCACGGGTCAGAGAGCAATCAGTACTACAACCCGGTGAAAGAGGACGTCCAG
GACTGTGGGAAAGTCCCCGACGTTTGCCAGCCCAGCCTGAGAGAGAAGGAGATCAAGAGCACTTGCAAGGAGGAGCAAAGGCCAAGGACA
GCCAACAAGGCCCCTGGGAGTAAAGGCGTGAAGCAGAAGTCCCCGCCCGCGGCCGTGGCCGTGGCGGTGAGCGCAGCCGCCCCGCCACCC
GCAGTGCCCTGTGCGCCCGCGGAGAACGCGCCCGCGCCTGCCCGGAGGTCCGCGGGCAAGAAGCCCACCAGGCGCACCGAGAGGACCTCA
GCCGGGGACGGCGCCAACTGCCACCGGCCCGAGGAGCCCGCGGCCGCGGACGCGCTGGGGACGAGCGTGGTGGTCCCCCCGGAGCCCACC
AAAACCAGGCCCTGTGGCAACAACAGAGCGAGCCACCGCAAGGAGCTGCGCTCCTCCGTGACCTGCGAGAAGCGCCGCACGCGGGGGCTA
AGCAGGATCGTCCCCAAATCCAAGGAGTTCATTGAGACAGAGTCGTCATCTTCATCCTCCTCCTCGGACTCCGACCTGGAGTCCGAGCAG
GAGGAGTACCCTCTGTCCAAAGCACAGACCGTGGCTGCCTCTGCCTCCTCCGGGAATGATCAGAGGCTGAAGGAGGCCGCTGCCAACGGG
GGCAGTGGTCCTAGGGCCCCTGTAGGCTCCATCAACGCCAGGACCACCAGTGACATCGCCAAGGAGCTGGAGGAGCAGTTCTACACACTG
GTCCCCTTTGGCCGGAACGAACTTCTCTCCCCTCTAAAGGACAGTGATGAGATCAGGTCTCTCTGGGTCAAAATCGACCTGACCCTCCTG
TCCAGGATCCCAGAACACCTGCCCCAGGAGCCAGGGGTATTGAGCGCCCCTGCCACCAAGGACTCTGAGAGCGCACCGCCCAGCCACACC
TCGGACACACCTGCAGAAAAGGCTTTGCCAAAATCCAAGAGGAAACGCAAGTGTGACAACGAAGACGACTACAGGGAGATCAAGAAGTCC
CAGGGAGAGAAAGACAGCTCTTCAAGACTGGCCACCTCCACCAGTAATACTTTGTCTGCAAACCACTGCAACATGAACATCAACAGTGTG
GCAATACCAATAAATAAAAATGAAAAAATGCTTCGGTCGCCCATCTCACCCCTCTCTGATGCATCTAAACACAAATACACCAGCGAGGAC
TTAACTTCTTCCAGCCGACCTAATGGCAACAGTTTGTTTACTTCAGCCTCTTCCAGCAAAAAGCCTAAGGCCGACAGCCAGCTGCAGCCT
CACGGCGGAGACCTCACGAAAGCAGCTCACAACAATTCTGAAAACATTCCCCTCCACAAGTCACGGCCGCAGACGAAGCCGTGGTCTCCA
GGCTCCAACGGCCACAGGGACTGCAAGAGGCAGAAACTTGTCTTCGATGATATGCCTCGCAGTGCCGATTATTTTATGCAAGAAGCTAAA
CGAATGAAGCATAAAGCAGATGCAATGGTGGAAAAGTTTGGAAAGGCTTTGAACTATGCTGAAGCAGCATTGTCGTTTATCGAGTGTGGA
AATGCAATGGAACAAGGCCCCATGGAATCCAAATCTCCTTATACGATGTATTCAGAAACAGTAGAGCTCATCAGGTATGCTATGAGACTA
AAAACCCACTCAGGCCCCAATGCCACACCAGAAGACAAACAACTGGCTGCATTATGTTACCGATGCCTGGCCCTCCTGTACTGGCGGATG
TTTCGACTCAAAAGGGACCACGCTGTAAAGTATTCAAAAGCACTAATCGACTATTTCAAGAACTCATCTAAAGCCGCCCAAGCCCCATCT
CCGTGGGGGGCCAGTGGAAAGAGCACTGGAACCCCATCCCCCATGTCTCCCAACCCCTCTCCCGCCAGCTCCGTGGGGTCTCAGGGCAGC
CTCTCCAACGCCAGCGCCCTGTCCCCGTCGACCATCGTCAGCATCCCACAGCGCATCCACCAGATGGCGGCCAACCACGTCAGCATCACC
AACAGCATCCTGCACAGCTACGACTACTGGGAGATGGCCGACAACCTGGCCAAGGAAAACCGAGAATTCTTCAACGACCTGGATCTGCTC
ATGGGGCCGGTCACCCTGCACAGCAGCATGGAGCACCTGGTCCAGTACTCCCAACAGGGCCTGCACTGGCTGCGGAACAGCGCCCACCTG
TCATAGGGACCTCACCCTGGGGCCAGAGTGGGCTCTGGTCTCCACAGATGGCTCAACGTTTTTGGACACTGTGCTACTGAAACTCCCAGC
CACAGCATTTATCAGACTGCGGTGAACATTTCCTCAGCATTGAACAATGATCTTTTGCAGGGCATGTGTGTTTGTATGTGTGGGTATATA
AGAAGCCGCCTGTGTATGTGTGTAAGATACACAGCTCTTCAGAACACACCTTCTTTGTCTAGTTTCCATAATCCCAGGCTAGACAAAGTG

>In-frame_ENST00000354520_ENST00000409579_AF422798_KMT2A_chr11_118353211_+_AFF3_chr2_100368765_length(amino acids)=2281AA_start in transcript=0_stop in transcript=6845
MAHSCRWRFPARPGTTGGGGGGGRRGLGGAPRQRVPALLLPPGPPVGGGGPGAPPSPPAVAAAAAAAGSSGAGVPGGAAAASAASSSSAS
SSSSSSSSASSGPALLRVGPGFDAALQVSAAIGTNLRRFRAVFGESGGGGGSGEDEQFLGFGSDEEVRVRSPTRSPSVKTSPRKPRGRPR
SGSDRNSAILSDPSVFSPLNKSETKSGDKIKKKDSKSIEKKRGRPPTFPGVKIKITHGKDISELPKGNKEDSLKKIKRTPSATFQQATKI
KKLRAGKLSPLKSKFKTGKLQIGRKGVQIVRRRGRPPSTERIKTPSGLLINSELEKPQKVRKDKEGTPPLTKEDKTVVRQSPRRIKPVRI
IPSSKRTDATIAKQLLQRAKKGAQKKIEKEAAQLQGRKVKTQVKNIRQFIMPVVSAISSRIIKTPRRFIEDEDYDPPIKIARLESTPNSR
FSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGS
RTTKKLSTLQSAPQQQTSSSPPPPLLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQ
YFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSN
RTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESA
EKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQ
SSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKILIKKGRGNLEKTNLDLGPTAPSLEKEKTLC
LSTPSSSTVKHSTSSIGSMLAQADKLPMTDKRVASLLKKAKAQLCKIEKSKSLKQTDQPKAQGQESDSSETSVRGPRIKHVCRRAAVALG
RKRAVFPDDMPTLSALPWEEREKILSSMGNDDKSSIAGSEDAEPLAPPIKPIKPVTRNKAPQEPPVKKGRRSRRCGQCPGCQVPEDCGVC
TNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKSSSE
PPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPR
PSIPVKQKPKEKEMTWLPPLSAIQAPGKVEPTKFPFPNKDSQLVSSGHNNPKKGDAEPESPDSGTSNTSMLEDDLKLSSDEEENEQQAAQ
RTALRALSDSAVVQQPNCRTSVPSSKGSSSSSSSGSSSSSSDSESSSGSDSETESSSSESEGSKPPHFSSPEAEPASSNKWQLDKWLNKV
NPHKPPILIQNESHGSESNQYYNPVKEDVQDCGKVPDVCQPSLREKEIKSTCKEEQRPRTANKAPGSKGVKQKSPPAAVAVAVSAAAPPP
AVPCAPAENAPAPARRSAGKKPTRRTERTSAGDGANCHRPEEPAAADALGTSVVVPPEPTKTRPCGNNRASHRKELRSSVTCEKRRTRGL
SRIVPKSKEFIETESSSSSSSSDSDLESEQEEYPLSKAQTVAASASSGNDQRLKEAAANGGSGPRAPVGSINARTTSDIAKELEEQFYTL
VPFGRNELLSPLKDSDEIRSLWVKIDLTLLSRIPEHLPQEPGVLSAPATKDSESAPPSHTSDTPAEKALPKSKRKRKCDNEDDYREIKKS
QGEKDSSSRLATSTSNTLSANHCNMNINSVAIPINKNEKMLRSPISPLSDASKHKYTSEDLTSSSRPNGNSLFTSASSSKKPKADSQLQP
HGGDLTKAAHNNSENIPLHKSRPQTKPWSPGSNGHRDCKRQKLVFDDMPRSADYFMQEAKRMKHKADAMVEKFGKALNYAEAALSFIECG
NAMEQGPMESKSPYTMYSETVELIRYAMRLKTHSGPNATPEDKQLAALCYRCLALLYWRMFRLKRDHAVKYSKALIDYFKNSSKAAQAPS
PWGASGKSTGTPSPMSPNPSPASSVGSQGSLSNASALSPSTIVSIPQRIHQMAANHVSITNSILHSYDYWEMADNLAKENREFFNDLDLL

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Fusion Gene PPI Analysis for KMT2A-AFF3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneKMT2Achr11:118353211chr2:100368765ENST00000354520+8351584_16001362.03932.0histone H3K4me3
HgeneKMT2Achr11:118353211chr2:100368765ENST00000389506+8361584_16001362.03970.0histone H3K4me3
HgeneKMT2Achr11:118353211chr2:100368765ENST00000534358+8361584_16001362.03973.0histone H3K4me3


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for KMT2A-AFF3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for KMT2A-AFF3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneKMT2AC2826025Mixed phenotype acute leukemia3ORPHANET
HgeneKMT2AC0023418leukemia2CTD_human
HgeneKMT2AC0023452Childhood Acute Lymphoblastic Leukemia2CTD_human
HgeneKMT2AC0023453L2 Acute Lymphoblastic Leukemia2CTD_human
HgeneKMT2AC0023466Leukemia, Monocytic, Chronic2CTD_human
HgeneKMT2AC0023467Leukemia, Myelocytic, Acute2CTD_human
HgeneKMT2AC0023470Myeloid Leukemia2CTD_human
HgeneKMT2AC0026998Acute Myeloid Leukemia, M12CTD_human
HgeneKMT2AC1854630Growth Deficiency and Mental Retardation with Facial Dysmorphism2CTD_human;GENOMICS_ENGLAND;ORPHANET
HgeneKMT2AC1879321Acute Myeloid Leukemia (AML-M2)2CTD_human
HgeneKMT2AC1961102Precursor Cell Lymphoblastic Leukemia Lymphoma2CTD_human
HgeneKMT2AC0001418Adenocarcinoma1CTD_human
HgeneKMT2AC0004403Autosome Abnormalities1CTD_human
HgeneKMT2AC0005684Malignant neoplasm of urinary bladder1CTD_human
HgeneKMT2AC0005695Bladder Neoplasm1CTD_human
HgeneKMT2AC0007138Carcinoma, Transitional Cell1CTD_human
HgeneKMT2AC0008625Chromosome Aberrations1CTD_human
HgeneKMT2AC0023448Lymphoid leukemia1CTD_human
HgeneKMT2AC0023465Acute monocytic leukemia1CTD_human
HgeneKMT2AC0023479Acute myelomonocytic leukemia1CTD_human
HgeneKMT2AC0024623Malignant neoplasm of stomach1CTD_human
HgeneKMT2AC0033578Prostatic Neoplasms1CTD_human
HgeneKMT2AC0036341Schizophrenia1PSYGENET
HgeneKMT2AC0038356Stomach Neoplasms1CTD_human
HgeneKMT2AC0149925Small cell carcinoma of lung1CTD_human
HgeneKMT2AC0205641Adenocarcinoma, Basal Cell1CTD_human
HgeneKMT2AC0205642Adenocarcinoma, Oxyphilic1CTD_human
HgeneKMT2AC0205643Carcinoma, Cribriform1CTD_human
HgeneKMT2AC0205644Carcinoma, Granular Cell1CTD_human
HgeneKMT2AC0205645Adenocarcinoma, Tubular1CTD_human
HgeneKMT2AC0270972Cornelia De Lange Syndrome1ORPHANET
HgeneKMT2AC0280141Acute Undifferentiated Leukemia1ORPHANET
HgeneKMT2AC0376358Malignant neoplasm of prostate1CTD_human
HgeneKMT2AC0856823Undifferentiated type acute leukemia1ORPHANET
HgeneKMT2AC1535926Neurodevelopmental Disorders1CTD_human
HgeneKMT2AC1708349Hereditary Diffuse Gastric Cancer1CTD_human
HgeneKMT2AC2239176Liver carcinoma1CTD_human
HgeneKMT2AC2930974Acute erythroleukemia1CTD_human
HgeneKMT2AC2930975Acute erythroleukemia - M6a subtype1CTD_human
HgeneKMT2AC2930976Acute myeloid leukemia FAB-M61CTD_human
HgeneKMT2AC2930977Acute erythroleukemia - M6b subtype1CTD_human
TgeneAFF3C0003873Rheumatoid Arthritis2CTD_human
TgeneAFF3C0013146Drug abuse1CTD_human
TgeneAFF3C0013170Drug habituation1CTD_human
TgeneAFF3C0013222Drug Use Disorders1CTD_human
TgeneAFF3C0029231Organic Mental Disorders, Substance-Induced1CTD_human
TgeneAFF3C0036572Seizures1GENOMICS_ENGLAND
TgeneAFF3C0038580Substance Dependence1CTD_human
TgeneAFF3C0038586Substance Use Disorders1CTD_human
TgeneAFF3C0236969Substance-Related Disorders1CTD_human
TgeneAFF3C0740858Substance abuse problem1CTD_human
TgeneAFF3C1510472Drug Dependence1CTD_human
TgeneAFF3C3714756Intellectual Disability1GENOMICS_ENGLAND
TgeneAFF3C4316881Prescription Drug Abuse1CTD_human