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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:KMT2A-MLLT1 (FusionGDB2 ID:42973)

Fusion Gene Summary for KMT2A-MLLT1

check button Fusion gene summary
Fusion gene informationFusion gene name: KMT2A-MLLT1
Fusion gene ID: 42973
HgeneTgene
Gene symbol

KMT2A

MLLT1

Gene ID

4297

4298

Gene namelysine methyltransferase 2AMLLT1 super elongation complex subunit
SynonymsALL-1|CXXC7|HRX|HTRX1|MLL|MLL1|MLL1A|TRX1|WDSTSENL|LTG19|YEATS1
Cytomap

11q23.3

19p13.3

Type of geneprotein-codingprotein-coding
Descriptionhistone-lysine N-methyltransferase 2ACXXC-type zinc finger protein 7lysine (K)-specific methyltransferase 2Alysine N-methyltransferase 2Amixed lineage leukemia 1myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)trithorax-likeprotein ENLCTC-503J8.6ENL/MLL fusionMLL/ENL fusion proteinMLLT1/MLL fusionYEATS domain-containing protein 1myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog); translocated to, 1myeloid/lymphoid or mixed-lineage leukemia (trithorax homol
Modification date2020031920200313
UniProtAcc

Q03164

Q13015

Ensembl transtripts involved in fusion geneENST00000534358, ENST00000389506, 
ENST00000354520, ENST00000420751, 
ENST00000252674, ENST00000585588, 
Fusion gene scores* DoF score79 X 196 X 13=20129212 X 23 X 7=1932
# samples 24130
** MAII scorelog2(241/201292*10)=-6.38411287931608
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(30/1932*10)=-2.68706068833989
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: KMT2A [Title/Abstract] AND MLLT1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointKMT2A(118355676)-MLLT1(6244694), # samples:1
KMT2A(118353562)-MLLT1(6271560), # samples:1
KMT2A(118359327)-MLLT1(6274154), # samples:1
KMT2A(118355096)-MLLT1(6273879), # samples:1
KMT2A(118355863)-MLLT1(6277299), # samples:1
KMT2A(118354246)-MLLT1(6272203), # samples:1
KMT2A(118359131)-MLLT1(6279120), # samples:1
KMT2A(118355030)-MLLT1(6230726), # samples:1
KMT2A(118355690)-MLLT1(6270772), # samples:1
KMT2A(118358677)-MLLT1(6273633), # samples:1
KMT2A(118357875)-MLLT1(6278587), # samples:1
KMT2A(118354553)-MLLT1(6275811), # samples:1
KMT2A(118353218)-MLLT1(6230726), # samples:1
KMT2A(118355030)-MLLT1(6222697), # samples:1
KMT2A(118355691)-MLLT1(6222697), # samples:1
MLLT1(6244692)-KMT2A(118355674), # samples:1
MLLT1(6262241)-KMT2A(118359329), # samples:1
MLLT1(6205645)-KMT2A(118359324), # samples:1
MLLT1(6276645)-KMT2A(118355687), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneKMT2A

GO:0044648

histone H3-K4 dimethylation

25561738

HgeneKMT2A

GO:0045944

positive regulation of transcription by RNA polymerase II

20861184

HgeneKMT2A

GO:0051568

histone H3-K4 methylation

19556245

HgeneKMT2A

GO:0065003

protein-containing complex assembly

15199122

HgeneKMT2A

GO:0080182

histone H3-K4 trimethylation

20861184

HgeneKMT2A

GO:0097692

histone H3-K4 monomethylation

25561738|26324722


check buttonFusion gene breakpoints across KMT2A (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across MLLT1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChiTaRS5.0N/AAF373585KMT2Achr11

118355676

+MLLT1chr19

6244694

-
ChiTaRS5.0N/AAM050746KMT2Achr11

118353562

+MLLT1chr19

6271560

-
ChiTaRS5.0N/AAM050801KMT2Achr11

118359327

+MLLT1chr19

6274154

-
ChiTaRS5.0N/AAM949721KMT2Achr11

118355096

+MLLT1chr19

6273879

-
ChiTaRS5.0N/AAM949722KMT2Achr11

118355863

+MLLT1chr19

6277299

-
ChiTaRS5.0N/AAM949723KMT2Achr11

118354246

+MLLT1chr19

6272203

-
ChiTaRS5.0N/AAM949724KMT2Achr11

118359131

+MLLT1chr19

6279120

-
ChiTaRS5.0N/AAY040555KMT2Achr11

118355030

+MLLT1chr19

6230726

-
ChiTaRS5.0N/AAY187921KMT2Achr11

118355690

+MLLT1chr19

6270772

-
ChiTaRS5.0N/AAY839729KMT2Achr11

118358677

+MLLT1chr19

6273633

-
ChiTaRS5.0N/AAY839733KMT2Achr11

118357875

+MLLT1chr19

6278587

-
ChiTaRS5.0N/AAY839735KMT2Achr11

118354553

+MLLT1chr19

6275811

-
ChiTaRS5.0N/ADQ224340KMT2Achr11

118353218

+MLLT1chr19

6230726

-
ChiTaRS5.0N/ADQ224341KMT2Achr11

118355030

+MLLT1chr19

6222697

-
ChiTaRS5.0N/ADQ224342KMT2Achr11

118355691

+MLLT1chr19

6222697

-


Top

Fusion Gene ORF analysis for KMT2A-MLLT1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000534358ENST00000252674KMT2Achr11

118355676

+MLLT1chr19

6244694

-
5CDS-intronENST00000534358ENST00000585588KMT2Achr11

118355676

+MLLT1chr19

6244694

-
5CDS-intronENST00000389506ENST00000252674KMT2Achr11

118355676

+MLLT1chr19

6244694

-
5CDS-intronENST00000389506ENST00000585588KMT2Achr11

118355676

+MLLT1chr19

6244694

-
intron-intronENST00000354520ENST00000252674KMT2Achr11

118355676

+MLLT1chr19

6244694

-
intron-intronENST00000354520ENST00000585588KMT2Achr11

118355676

+MLLT1chr19

6244694

-
intron-intronENST00000420751ENST00000252674KMT2Achr11

118355676

+MLLT1chr19

6244694

-
intron-intronENST00000420751ENST00000585588KMT2Achr11

118355676

+MLLT1chr19

6244694

-
intron-intronENST00000534358ENST00000252674KMT2Achr11

118353562

+MLLT1chr19

6271560

-
intron-intronENST00000534358ENST00000585588KMT2Achr11

118353562

+MLLT1chr19

6271560

-
intron-intronENST00000389506ENST00000252674KMT2Achr11

118353562

+MLLT1chr19

6271560

-
intron-intronENST00000389506ENST00000585588KMT2Achr11

118353562

+MLLT1chr19

6271560

-
intron-intronENST00000354520ENST00000252674KMT2Achr11

118353562

+MLLT1chr19

6271560

-
intron-intronENST00000354520ENST00000585588KMT2Achr11

118353562

+MLLT1chr19

6271560

-
intron-intronENST00000420751ENST00000252674KMT2Achr11

118353562

+MLLT1chr19

6271560

-
intron-intronENST00000420751ENST00000585588KMT2Achr11

118353562

+MLLT1chr19

6271560

-
intron-intronENST00000534358ENST00000252674KMT2Achr11

118359327

+MLLT1chr19

6274154

-
intron-intronENST00000534358ENST00000585588KMT2Achr11

118359327

+MLLT1chr19

6274154

-
intron-intronENST00000389506ENST00000252674KMT2Achr11

118359327

+MLLT1chr19

6274154

-
intron-intronENST00000389506ENST00000585588KMT2Achr11

118359327

+MLLT1chr19

6274154

-
intron-intronENST00000354520ENST00000252674KMT2Achr11

118359327

+MLLT1chr19

6274154

-
intron-intronENST00000354520ENST00000585588KMT2Achr11

118359327

+MLLT1chr19

6274154

-
intron-intronENST00000420751ENST00000252674KMT2Achr11

118359327

+MLLT1chr19

6274154

-
intron-intronENST00000420751ENST00000585588KMT2Achr11

118359327

+MLLT1chr19

6274154

-
intron-intronENST00000534358ENST00000252674KMT2Achr11

118355096

+MLLT1chr19

6273879

-
intron-intronENST00000534358ENST00000585588KMT2Achr11

118355096

+MLLT1chr19

6273879

-
intron-intronENST00000389506ENST00000252674KMT2Achr11

118355096

+MLLT1chr19

6273879

-
intron-intronENST00000389506ENST00000585588KMT2Achr11

118355096

+MLLT1chr19

6273879

-
intron-intronENST00000354520ENST00000252674KMT2Achr11

118355096

+MLLT1chr19

6273879

-
intron-intronENST00000354520ENST00000585588KMT2Achr11

118355096

+MLLT1chr19

6273879

-
intron-intronENST00000420751ENST00000252674KMT2Achr11

118355096

+MLLT1chr19

6273879

-
intron-intronENST00000420751ENST00000585588KMT2Achr11

118355096

+MLLT1chr19

6273879

-
intron-intronENST00000534358ENST00000252674KMT2Achr11

118355863

+MLLT1chr19

6277299

-
intron-intronENST00000534358ENST00000585588KMT2Achr11

118355863

+MLLT1chr19

6277299

-
intron-intronENST00000389506ENST00000252674KMT2Achr11

118355863

+MLLT1chr19

6277299

-
intron-intronENST00000389506ENST00000585588KMT2Achr11

118355863

+MLLT1chr19

6277299

-
intron-intronENST00000354520ENST00000252674KMT2Achr11

118355863

+MLLT1chr19

6277299

-
intron-intronENST00000354520ENST00000585588KMT2Achr11

118355863

+MLLT1chr19

6277299

-
intron-intronENST00000420751ENST00000252674KMT2Achr11

118355863

+MLLT1chr19

6277299

-
intron-intronENST00000420751ENST00000585588KMT2Achr11

118355863

+MLLT1chr19

6277299

-
intron-intronENST00000534358ENST00000252674KMT2Achr11

118354246

+MLLT1chr19

6272203

-
intron-intronENST00000534358ENST00000585588KMT2Achr11

118354246

+MLLT1chr19

6272203

-
intron-intronENST00000389506ENST00000252674KMT2Achr11

118354246

+MLLT1chr19

6272203

-
intron-intronENST00000389506ENST00000585588KMT2Achr11

118354246

+MLLT1chr19

6272203

-
intron-intronENST00000354520ENST00000252674KMT2Achr11

118354246

+MLLT1chr19

6272203

-
intron-intronENST00000354520ENST00000585588KMT2Achr11

118354246

+MLLT1chr19

6272203

-
intron-intronENST00000420751ENST00000252674KMT2Achr11

118354246

+MLLT1chr19

6272203

-
intron-intronENST00000420751ENST00000585588KMT2Achr11

118354246

+MLLT1chr19

6272203

-
intron-intronENST00000534358ENST00000252674KMT2Achr11

118359131

+MLLT1chr19

6279120

-
intron-intronENST00000534358ENST00000585588KMT2Achr11

118359131

+MLLT1chr19

6279120

-
intron-intronENST00000389506ENST00000252674KMT2Achr11

118359131

+MLLT1chr19

6279120

-
intron-intronENST00000389506ENST00000585588KMT2Achr11

118359131

+MLLT1chr19

6279120

-
intron-intronENST00000354520ENST00000252674KMT2Achr11

118359131

+MLLT1chr19

6279120

-
intron-intronENST00000354520ENST00000585588KMT2Achr11

118359131

+MLLT1chr19

6279120

-
intron-intronENST00000420751ENST00000252674KMT2Achr11

118359131

+MLLT1chr19

6279120

-
intron-intronENST00000420751ENST00000585588KMT2Achr11

118359131

+MLLT1chr19

6279120

-
In-frameENST00000534358ENST00000252674KMT2Achr11

118355030

+MLLT1chr19

6230726

-
5CDS-intronENST00000534358ENST00000585588KMT2Achr11

118355030

+MLLT1chr19

6230726

-
In-frameENST00000389506ENST00000252674KMT2Achr11

118355030

+MLLT1chr19

6230726

-
5CDS-intronENST00000389506ENST00000585588KMT2Achr11

118355030

+MLLT1chr19

6230726

-
In-frameENST00000354520ENST00000252674KMT2Achr11

118355030

+MLLT1chr19

6230726

-
5CDS-intronENST00000354520ENST00000585588KMT2Achr11

118355030

+MLLT1chr19

6230726

-
3UTR-3CDSENST00000420751ENST00000252674KMT2Achr11

118355030

+MLLT1chr19

6230726

-
3UTR-intronENST00000420751ENST00000585588KMT2Achr11

118355030

+MLLT1chr19

6230726

-
In-frameENST00000534358ENST00000252674KMT2Achr11

118355690

+MLLT1chr19

6270772

-
5CDS-intronENST00000534358ENST00000585588KMT2Achr11

118355690

+MLLT1chr19

6270772

-
In-frameENST00000389506ENST00000252674KMT2Achr11

118355690

+MLLT1chr19

6270772

-
5CDS-intronENST00000389506ENST00000585588KMT2Achr11

118355690

+MLLT1chr19

6270772

-
intron-3CDSENST00000354520ENST00000252674KMT2Achr11

118355690

+MLLT1chr19

6270772

-
intron-intronENST00000354520ENST00000585588KMT2Achr11

118355690

+MLLT1chr19

6270772

-
intron-3CDSENST00000420751ENST00000252674KMT2Achr11

118355690

+MLLT1chr19

6270772

-
intron-intronENST00000420751ENST00000585588KMT2Achr11

118355690

+MLLT1chr19

6270772

-
intron-intronENST00000534358ENST00000252674KMT2Achr11

118358677

+MLLT1chr19

6273633

-
intron-intronENST00000534358ENST00000585588KMT2Achr11

118358677

+MLLT1chr19

6273633

-
intron-intronENST00000389506ENST00000252674KMT2Achr11

118358677

+MLLT1chr19

6273633

-
intron-intronENST00000389506ENST00000585588KMT2Achr11

118358677

+MLLT1chr19

6273633

-
intron-intronENST00000354520ENST00000252674KMT2Achr11

118358677

+MLLT1chr19

6273633

-
intron-intronENST00000354520ENST00000585588KMT2Achr11

118358677

+MLLT1chr19

6273633

-
intron-intronENST00000420751ENST00000252674KMT2Achr11

118358677

+MLLT1chr19

6273633

-
intron-intronENST00000420751ENST00000585588KMT2Achr11

118358677

+MLLT1chr19

6273633

-
intron-intronENST00000534358ENST00000252674KMT2Achr11

118357875

+MLLT1chr19

6278587

-
intron-intronENST00000534358ENST00000585588KMT2Achr11

118357875

+MLLT1chr19

6278587

-
intron-intronENST00000389506ENST00000252674KMT2Achr11

118357875

+MLLT1chr19

6278587

-
intron-intronENST00000389506ENST00000585588KMT2Achr11

118357875

+MLLT1chr19

6278587

-
intron-intronENST00000354520ENST00000252674KMT2Achr11

118357875

+MLLT1chr19

6278587

-
intron-intronENST00000354520ENST00000585588KMT2Achr11

118357875

+MLLT1chr19

6278587

-
intron-intronENST00000420751ENST00000252674KMT2Achr11

118357875

+MLLT1chr19

6278587

-
intron-intronENST00000420751ENST00000585588KMT2Achr11

118357875

+MLLT1chr19

6278587

-
intron-intronENST00000534358ENST00000252674KMT2Achr11

118354553

+MLLT1chr19

6275811

-
intron-intronENST00000534358ENST00000585588KMT2Achr11

118354553

+MLLT1chr19

6275811

-
intron-intronENST00000389506ENST00000252674KMT2Achr11

118354553

+MLLT1chr19

6275811

-
intron-intronENST00000389506ENST00000585588KMT2Achr11

118354553

+MLLT1chr19

6275811

-
intron-intronENST00000354520ENST00000252674KMT2Achr11

118354553

+MLLT1chr19

6275811

-
intron-intronENST00000354520ENST00000585588KMT2Achr11

118354553

+MLLT1chr19

6275811

-
intron-intronENST00000420751ENST00000252674KMT2Achr11

118354553

+MLLT1chr19

6275811

-
intron-intronENST00000420751ENST00000585588KMT2Achr11

118354553

+MLLT1chr19

6275811

-
intron-3CDSENST00000534358ENST00000252674KMT2Achr11

118353218

+MLLT1chr19

6230726

-
intron-intronENST00000534358ENST00000585588KMT2Achr11

118353218

+MLLT1chr19

6230726

-
intron-3CDSENST00000389506ENST00000252674KMT2Achr11

118353218

+MLLT1chr19

6230726

-
intron-intronENST00000389506ENST00000585588KMT2Achr11

118353218

+MLLT1chr19

6230726

-
intron-3CDSENST00000354520ENST00000252674KMT2Achr11

118353218

+MLLT1chr19

6230726

-
intron-intronENST00000354520ENST00000585588KMT2Achr11

118353218

+MLLT1chr19

6230726

-
intron-3CDSENST00000420751ENST00000252674KMT2Achr11

118353218

+MLLT1chr19

6230726

-
intron-intronENST00000420751ENST00000585588KMT2Achr11

118353218

+MLLT1chr19

6230726

-
In-frameENST00000534358ENST00000252674KMT2Achr11

118355030

+MLLT1chr19

6222697

-
5CDS-intronENST00000534358ENST00000585588KMT2Achr11

118355030

+MLLT1chr19

6222697

-
In-frameENST00000389506ENST00000252674KMT2Achr11

118355030

+MLLT1chr19

6222697

-
5CDS-intronENST00000389506ENST00000585588KMT2Achr11

118355030

+MLLT1chr19

6222697

-
In-frameENST00000354520ENST00000252674KMT2Achr11

118355030

+MLLT1chr19

6222697

-
5CDS-intronENST00000354520ENST00000585588KMT2Achr11

118355030

+MLLT1chr19

6222697

-
3UTR-3CDSENST00000420751ENST00000252674KMT2Achr11

118355030

+MLLT1chr19

6222697

-
3UTR-intronENST00000420751ENST00000585588KMT2Achr11

118355030

+MLLT1chr19

6222697

-
In-frameENST00000534358ENST00000252674KMT2Achr11

118355691

+MLLT1chr19

6222697

-
5CDS-intronENST00000534358ENST00000585588KMT2Achr11

118355691

+MLLT1chr19

6222697

-
In-frameENST00000389506ENST00000252674KMT2Achr11

118355691

+MLLT1chr19

6222697

-
5CDS-intronENST00000389506ENST00000585588KMT2Achr11

118355691

+MLLT1chr19

6222697

-
intron-3CDSENST00000354520ENST00000252674KMT2Achr11

118355691

+MLLT1chr19

6222697

-
intron-intronENST00000354520ENST00000585588KMT2Achr11

118355691

+MLLT1chr19

6222697

-
intron-3CDSENST00000420751ENST00000252674KMT2Achr11

118355691

+MLLT1chr19

6222697

-
intron-intronENST00000420751ENST00000585588KMT2Achr11

118355691

+MLLT1chr19

6222697

-
3UTR-3CDSENST00000420751ENST00000252674KMT2Achr11

118355029

+MLLT1chr19

6222695

-
3UTR-3CDSENST00000420751ENST00000252674KMT2Achr11

118355029

+MLLT1chr19

6270770

-
3UTR-intronENST00000420751ENST00000585588KMT2Achr11

118355029

+MLLT1chr19

6222695

-
3UTR-intronENST00000420751ENST00000585588KMT2Achr11

118355029

+MLLT1chr19

6270770

-
5CDS-intronENST00000354520ENST00000585588KMT2Achr11

118350953

+MLLT1chr19

6222695

-
5CDS-intronENST00000354520ENST00000585588KMT2Achr11

118353210

+MLLT1chr19

6218052

-
5CDS-intronENST00000354520ENST00000585588KMT2Achr11

118353210

+MLLT1chr19

6222695

-
5CDS-intronENST00000354520ENST00000585588KMT2Achr11

118353210

+MLLT1chr19

6230724

-
5CDS-intronENST00000354520ENST00000585588KMT2Achr11

118355029

+MLLT1chr19

6222695

-
5CDS-intronENST00000354520ENST00000585588KMT2Achr11

118355029

+MLLT1chr19

6270770

-
5CDS-intronENST00000389506ENST00000585588KMT2Achr11

118350953

+MLLT1chr19

6222695

-
5CDS-intronENST00000389506ENST00000585588KMT2Achr11

118353210

+MLLT1chr19

6218052

-
5CDS-intronENST00000389506ENST00000585588KMT2Achr11

118353210

+MLLT1chr19

6222695

-
5CDS-intronENST00000389506ENST00000585588KMT2Achr11

118353210

+MLLT1chr19

6230724

-
5CDS-intronENST00000389506ENST00000585588KMT2Achr11

118355029

+MLLT1chr19

6222695

-
5CDS-intronENST00000389506ENST00000585588KMT2Achr11

118355029

+MLLT1chr19

6270770

-
5CDS-intronENST00000389506ENST00000585588KMT2Achr11

118355690

+MLLT1chr19

6218052

-
5CDS-intronENST00000389506ENST00000585588KMT2Achr11

118355690

+MLLT1chr19

6222695

-
5CDS-intronENST00000389506ENST00000585588KMT2Achr11

118355690

+MLLT1chr19

6230724

-
5CDS-intronENST00000389506ENST00000585588KMT2Achr11

118355690

+MLLT1chr19

6270770

-
5CDS-intronENST00000534358ENST00000585588KMT2Achr11

118350953

+MLLT1chr19

6222695

-
5CDS-intronENST00000534358ENST00000585588KMT2Achr11

118353210

+MLLT1chr19

6218052

-
5CDS-intronENST00000534358ENST00000585588KMT2Achr11

118353210

+MLLT1chr19

6222695

-
5CDS-intronENST00000534358ENST00000585588KMT2Achr11

118353210

+MLLT1chr19

6230724

-
5CDS-intronENST00000534358ENST00000585588KMT2Achr11

118355029

+MLLT1chr19

6222695

-
5CDS-intronENST00000534358ENST00000585588KMT2Achr11

118355029

+MLLT1chr19

6270770

-
5CDS-intronENST00000534358ENST00000585588KMT2Achr11

118355690

+MLLT1chr19

6218052

-
5CDS-intronENST00000534358ENST00000585588KMT2Achr11

118355690

+MLLT1chr19

6222695

-
5CDS-intronENST00000534358ENST00000585588KMT2Achr11

118355690

+MLLT1chr19

6230724

-
5CDS-intronENST00000534358ENST00000585588KMT2Achr11

118355690

+MLLT1chr19

6270770

-
Frame-shiftENST00000354520ENST00000252674KMT2Achr11

118350953

+MLLT1chr19

6222695

-
Frame-shiftENST00000389506ENST00000252674KMT2Achr11

118350953

+MLLT1chr19

6222695

-
Frame-shiftENST00000534358ENST00000252674KMT2Achr11

118350953

+MLLT1chr19

6222695

-
In-frameENST00000354520ENST00000252674KMT2Achr11

118353210

+MLLT1chr19

6218052

-
In-frameENST00000354520ENST00000252674KMT2Achr11

118353210

+MLLT1chr19

6222695

-
In-frameENST00000354520ENST00000252674KMT2Achr11

118353210

+MLLT1chr19

6230724

-
In-frameENST00000354520ENST00000252674KMT2Achr11

118355029

+MLLT1chr19

6222695

-
In-frameENST00000354520ENST00000252674KMT2Achr11

118355029

+MLLT1chr19

6270770

-
In-frameENST00000389506ENST00000252674KMT2Achr11

118353210

+MLLT1chr19

6218052

-
In-frameENST00000389506ENST00000252674KMT2Achr11

118353210

+MLLT1chr19

6222695

-
In-frameENST00000389506ENST00000252674KMT2Achr11

118353210

+MLLT1chr19

6230724

-
In-frameENST00000389506ENST00000252674KMT2Achr11

118355029

+MLLT1chr19

6222695

-
In-frameENST00000389506ENST00000252674KMT2Achr11

118355029

+MLLT1chr19

6270770

-
In-frameENST00000389506ENST00000252674KMT2Achr11

118355690

+MLLT1chr19

6218052

-
In-frameENST00000389506ENST00000252674KMT2Achr11

118355690

+MLLT1chr19

6222695

-
In-frameENST00000389506ENST00000252674KMT2Achr11

118355690

+MLLT1chr19

6230724

-
In-frameENST00000389506ENST00000252674KMT2Achr11

118355690

+MLLT1chr19

6270770

-
In-frameENST00000534358ENST00000252674KMT2Achr11

118353210

+MLLT1chr19

6218052

-
In-frameENST00000534358ENST00000252674KMT2Achr11

118353210

+MLLT1chr19

6222695

-
In-frameENST00000534358ENST00000252674KMT2Achr11

118353210

+MLLT1chr19

6230724

-
In-frameENST00000534358ENST00000252674KMT2Achr11

118355029

+MLLT1chr19

6222695

-
In-frameENST00000534358ENST00000252674KMT2Achr11

118355029

+MLLT1chr19

6270770

-
In-frameENST00000534358ENST00000252674KMT2Achr11

118355690

+MLLT1chr19

6218052

-
In-frameENST00000534358ENST00000252674KMT2Achr11

118355690

+MLLT1chr19

6222695

-
In-frameENST00000534358ENST00000252674KMT2Achr11

118355690

+MLLT1chr19

6230724

-
In-frameENST00000534358ENST00000252674KMT2Achr11

118355690

+MLLT1chr19

6270770

-
intron-3CDSENST00000354520ENST00000252674KMT2Achr11

118355690

+MLLT1chr19

6218052

-
intron-3CDSENST00000354520ENST00000252674KMT2Achr11

118355690

+MLLT1chr19

6222695

-
intron-3CDSENST00000354520ENST00000252674KMT2Achr11

118355690

+MLLT1chr19

6230724

-
intron-3CDSENST00000354520ENST00000252674KMT2Achr11

118355690

+MLLT1chr19

6270770

-
intron-3CDSENST00000420751ENST00000252674KMT2Achr11

118350953

+MLLT1chr19

6222695

-
intron-3CDSENST00000420751ENST00000252674KMT2Achr11

118353210

+MLLT1chr19

6218052

-
intron-3CDSENST00000420751ENST00000252674KMT2Achr11

118353210

+MLLT1chr19

6222695

-
intron-3CDSENST00000420751ENST00000252674KMT2Achr11

118353210

+MLLT1chr19

6230724

-
intron-3CDSENST00000420751ENST00000252674KMT2Achr11

118355690

+MLLT1chr19

6218052

-
intron-3CDSENST00000420751ENST00000252674KMT2Achr11

118355690

+MLLT1chr19

6222695

-
intron-3CDSENST00000420751ENST00000252674KMT2Achr11

118355690

+MLLT1chr19

6230724

-
intron-3CDSENST00000420751ENST00000252674KMT2Achr11

118355690

+MLLT1chr19

6270770

-
intron-intronENST00000354520ENST00000585588KMT2Achr11

118355690

+MLLT1chr19

6218052

-
intron-intronENST00000354520ENST00000585588KMT2Achr11

118355690

+MLLT1chr19

6222695

-
intron-intronENST00000354520ENST00000585588KMT2Achr11

118355690

+MLLT1chr19

6230724

-
intron-intronENST00000354520ENST00000585588KMT2Achr11

118355690

+MLLT1chr19

6270770

-
intron-intronENST00000420751ENST00000585588KMT2Achr11

118350953

+MLLT1chr19

6222695

-
intron-intronENST00000420751ENST00000585588KMT2Achr11

118353210

+MLLT1chr19

6218052

-
intron-intronENST00000420751ENST00000585588KMT2Achr11

118353210

+MLLT1chr19

6222695

-
intron-intronENST00000420751ENST00000585588KMT2Achr11

118353210

+MLLT1chr19

6230724

-
intron-intronENST00000420751ENST00000585588KMT2Achr11

118355690

+MLLT1chr19

6218052

-
intron-intronENST00000420751ENST00000585588KMT2Achr11

118355690

+MLLT1chr19

6222695

-
intron-intronENST00000420751ENST00000585588KMT2Achr11

118355690

+MLLT1chr19

6230724

-
intron-intronENST00000420751ENST00000585588KMT2Achr11

118355690

+MLLT1chr19

6270770

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000534358KMT2Achr11118355030+ENST00000252674MLLT1chr196230726-573242412356441873
ENST00000389506KMT2Achr11118355030+ENST00000252674MLLT1chr196230726-57094218056211873
ENST00000354520KMT2Achr11118355030+ENST00000252674MLLT1chr196230726-57094218056211873
ENST00000534358KMT2Achr11118355690+ENST00000252674MLLT1chr196270772-611043552360221999
ENST00000389506KMT2Achr11118355690+ENST00000252674MLLT1chr196270772-60874332059991999
ENST00000534358KMT2Achr11118355030+ENST00000252674MLLT1chr196222697-546242412353741783
ENST00000389506KMT2Achr11118355030+ENST00000252674MLLT1chr196222697-54394218053511783
ENST00000354520KMT2Achr11118355030+ENST00000252674MLLT1chr196222697-54394218053511783
ENST00000534358KMT2Achr11118355691+ENST00000252674MLLT1chr196222697-557643552354881821
ENST00000389506KMT2Achr11118355691+ENST00000252674MLLT1chr196222697-55534332054651821

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000534358ENST00000252674KMT2Achr11118355030+MLLT1chr196230726-0.0020094880.9979905
ENST00000389506ENST00000252674KMT2Achr11118355030+MLLT1chr196230726-0.0019711270.9980288
ENST00000354520ENST00000252674KMT2Achr11118355030+MLLT1chr196230726-0.0019711270.9980288
ENST00000534358ENST00000252674KMT2Achr11118355690+MLLT1chr196270772-0.0026394580.9973605
ENST00000389506ENST00000252674KMT2Achr11118355690+MLLT1chr196270772-0.0025876670.9974124
ENST00000534358ENST00000252674KMT2Achr11118355030+MLLT1chr196222697-0.0018062170.9981938
ENST00000389506ENST00000252674KMT2Achr11118355030+MLLT1chr196222697-0.0017686040.9982315
ENST00000354520ENST00000252674KMT2Achr11118355030+MLLT1chr196222697-0.0017686040.9982315
ENST00000534358ENST00000252674KMT2Achr11118355691+MLLT1chr196222697-0.0009111970.99908876
ENST00000389506ENST00000252674KMT2Achr11118355691+MLLT1chr196222697-0.0008913960.9991086

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Fusion Genomic Features for KMT2A-MLLT1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for KMT2A-MLLT1


check button Go to

FGviewer for the breakpoints of chr11:118355030-chr19:6230726

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
KMT2A

Q03164

MLLT1

Q13015

FUNCTION: Histone methyltransferase that plays an essential role in early development and hematopoiesis (PubMed:15960975, PubMed:12453419, PubMed:15960975, PubMed:19556245, PubMed:19187761, PubMed:20677832, PubMed:21220120, PubMed:26886794). Catalytic subunit of the MLL1/MLL complex, a multiprotein complex that mediates both methylation of 'Lys-4' of histone H3 (H3K4me) complex and acetylation of 'Lys-16' of histone H4 (H4K16ac) (PubMed:15960975, PubMed:12453419, PubMed:15960975, PubMed:19556245, PubMed:24235145, PubMed:19187761, PubMed:20677832, PubMed:21220120, PubMed:26886794). Catalyzes methyl group transfer from S-adenosyl-L-methionine to the epsilon-amino group of 'Lys-4' of histone H3 (H3K4) via a non-processive mechanism. Part of chromatin remodeling machinery predominantly forms H3K4me1 and H3K4me2 methylation marks at active chromatin sites where transcription and DNA repair take place (PubMed:25561738, PubMed:15960975, PubMed:12453419, PubMed:15960975, PubMed:19556245, PubMed:19187761, PubMed:20677832, PubMed:21220120, PubMed:26886794). Has weak methyltransferase activity by itself, and requires other component of the MLL1/MLL complex to obtain full methyltransferase activity (PubMed:19187761, PubMed:26886794). Has no activity toward histone H3 phosphorylated on 'Thr-3', less activity toward H3 dimethylated on 'Arg-8' or 'Lys-9', while it has higher activity toward H3 acetylated on 'Lys-9' (PubMed:19187761). Binds to unmethylated CpG elements in the promoter of target genes and helps maintain them in the nonmethylated state (PubMed:20010842). Required for transcriptional activation of HOXA9 (PubMed:12453419, PubMed:20677832, PubMed:20010842). Promotes PPP1R15A-induced apoptosis (PubMed:10490642). Plays a critical role in the control of circadian gene expression and is essential for the transcriptional activation mediated by the CLOCK-ARNTL/BMAL1 heterodimer (By similarity). Establishes a permissive chromatin state for circadian transcription by mediating a rhythmic methylation of 'Lys-4' of histone H3 (H3K4me) and this histone modification directs the circadian acetylation at H3K9 and H3K14 allowing the recruitment of CLOCK-ARNTL/BMAL1 to chromatin (By similarity). Also has auto-methylation activity on Cys-3882 in absence of histone H3 substrate (PubMed:24235145). {ECO:0000250|UniProtKB:P55200, ECO:0000269|PubMed:10490642, ECO:0000269|PubMed:12453419, ECO:0000269|PubMed:15960975, ECO:0000269|PubMed:19187761, ECO:0000269|PubMed:19556245, ECO:0000269|PubMed:20010842, ECO:0000269|PubMed:21220120, ECO:0000269|PubMed:24235145, ECO:0000269|PubMed:26886794, ECO:0000305|PubMed:20677832}.FUNCTION: Cofactor for the transcription factor TCF7 (PubMed:26079538). Involved in regulation of lymphoid development by driving multipotent hematopoietic progenitor cells towards a T cell fate (PubMed:21715312). {ECO:0000269|PubMed:21715312, ECO:0000269|PubMed:26079538}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneKMT2Achr11:118355030chr19:6222697ENST00000354520+935137_1431406.03932.0Compositional biasNote=Poly-Gly
HgeneKMT2Achr11:118355030chr19:6222697ENST00000354520+93517_1021406.03932.0Compositional biasNote=Ala/Gly/Ser-rich
HgeneKMT2Achr11:118355030chr19:6222697ENST00000354520+935561_5641406.03932.0Compositional biasNote=Poly-Pro
HgeneKMT2Achr11:118355030chr19:6222697ENST00000354520+935568_5711406.03932.0Compositional biasNote=Poly-Pro
HgeneKMT2Achr11:118355030chr19:6222697ENST00000389506+936137_1431406.03970.0Compositional biasNote=Poly-Gly
HgeneKMT2Achr11:118355030chr19:6222697ENST00000389506+93617_1021406.03970.0Compositional biasNote=Ala/Gly/Ser-rich
HgeneKMT2Achr11:118355030chr19:6222697ENST00000389506+936561_5641406.03970.0Compositional biasNote=Poly-Pro
HgeneKMT2Achr11:118355030chr19:6222697ENST00000389506+936568_5711406.03970.0Compositional biasNote=Poly-Pro
HgeneKMT2Achr11:118355030chr19:6222697ENST00000534358+936137_1431406.03973.0Compositional biasNote=Poly-Gly
HgeneKMT2Achr11:118355030chr19:6222697ENST00000534358+93617_1021406.03973.0Compositional biasNote=Ala/Gly/Ser-rich
HgeneKMT2Achr11:118355030chr19:6222697ENST00000534358+936561_5641406.03973.0Compositional biasNote=Poly-Pro
HgeneKMT2Achr11:118355030chr19:6222697ENST00000534358+936568_5711406.03973.0Compositional biasNote=Poly-Pro
HgeneKMT2Achr11:118355030chr19:6230726ENST00000354520+935137_1431406.03932.0Compositional biasNote=Poly-Gly
HgeneKMT2Achr11:118355030chr19:6230726ENST00000354520+93517_1021406.03932.0Compositional biasNote=Ala/Gly/Ser-rich
HgeneKMT2Achr11:118355030chr19:6230726ENST00000354520+935561_5641406.03932.0Compositional biasNote=Poly-Pro
HgeneKMT2Achr11:118355030chr19:6230726ENST00000354520+935568_5711406.03932.0Compositional biasNote=Poly-Pro
HgeneKMT2Achr11:118355030chr19:6230726ENST00000389506+936137_1431406.03970.0Compositional biasNote=Poly-Gly
HgeneKMT2Achr11:118355030chr19:6230726ENST00000389506+93617_1021406.03970.0Compositional biasNote=Ala/Gly/Ser-rich
HgeneKMT2Achr11:118355030chr19:6230726ENST00000389506+936561_5641406.03970.0Compositional biasNote=Poly-Pro
HgeneKMT2Achr11:118355030chr19:6230726ENST00000389506+936568_5711406.03970.0Compositional biasNote=Poly-Pro
HgeneKMT2Achr11:118355030chr19:6230726ENST00000534358+936137_1431406.03973.0Compositional biasNote=Poly-Gly
HgeneKMT2Achr11:118355030chr19:6230726ENST00000534358+93617_1021406.03973.0Compositional biasNote=Ala/Gly/Ser-rich
HgeneKMT2Achr11:118355030chr19:6230726ENST00000534358+936561_5641406.03973.0Compositional biasNote=Poly-Pro
HgeneKMT2Achr11:118355030chr19:6230726ENST00000534358+936568_5711406.03973.0Compositional biasNote=Poly-Pro
HgeneKMT2Achr11:118355690chr19:6270772ENST00000389506+1036137_1431444.03970.0Compositional biasNote=Poly-Gly
HgeneKMT2Achr11:118355690chr19:6270772ENST00000389506+103617_1021444.03970.0Compositional biasNote=Ala/Gly/Ser-rich
HgeneKMT2Achr11:118355690chr19:6270772ENST00000389506+1036561_5641444.03970.0Compositional biasNote=Poly-Pro
HgeneKMT2Achr11:118355690chr19:6270772ENST00000389506+1036568_5711444.03970.0Compositional biasNote=Poly-Pro
HgeneKMT2Achr11:118355690chr19:6270772ENST00000534358+1036137_1431444.03973.0Compositional biasNote=Poly-Gly
HgeneKMT2Achr11:118355690chr19:6270772ENST00000534358+103617_1021444.03973.0Compositional biasNote=Ala/Gly/Ser-rich
HgeneKMT2Achr11:118355690chr19:6270772ENST00000534358+1036561_5641444.03973.0Compositional biasNote=Poly-Pro
HgeneKMT2Achr11:118355690chr19:6270772ENST00000534358+1036568_5711444.03973.0Compositional biasNote=Poly-Pro
HgeneKMT2Achr11:118355691chr19:6222697ENST00000389506+1036137_1431444.03970.0Compositional biasNote=Poly-Gly
HgeneKMT2Achr11:118355691chr19:6222697ENST00000389506+103617_1021444.03970.0Compositional biasNote=Ala/Gly/Ser-rich
HgeneKMT2Achr11:118355691chr19:6222697ENST00000389506+1036561_5641444.03970.0Compositional biasNote=Poly-Pro
HgeneKMT2Achr11:118355691chr19:6222697ENST00000389506+1036568_5711444.03970.0Compositional biasNote=Poly-Pro
HgeneKMT2Achr11:118355691chr19:6222697ENST00000534358+1036137_1431444.03973.0Compositional biasNote=Poly-Gly
HgeneKMT2Achr11:118355691chr19:6222697ENST00000534358+103617_1021444.03973.0Compositional biasNote=Ala/Gly/Ser-rich
HgeneKMT2Achr11:118355691chr19:6222697ENST00000534358+1036561_5641444.03973.0Compositional biasNote=Poly-Pro
HgeneKMT2Achr11:118355691chr19:6222697ENST00000534358+1036568_5711444.03973.0Compositional biasNote=Poly-Pro
HgeneKMT2Achr11:118355030chr19:6222697ENST00000354520+935169_1801406.03932.0DNA bindingNote=A.T hook 1
HgeneKMT2Achr11:118355030chr19:6222697ENST00000354520+935217_2271406.03932.0DNA bindingNote=A.T hook 2
HgeneKMT2Achr11:118355030chr19:6222697ENST00000354520+935301_3091406.03932.0DNA bindingNote=A.T hook 3
HgeneKMT2Achr11:118355030chr19:6222697ENST00000389506+936169_1801406.03970.0DNA bindingNote=A.T hook 1
HgeneKMT2Achr11:118355030chr19:6222697ENST00000389506+936217_2271406.03970.0DNA bindingNote=A.T hook 2
HgeneKMT2Achr11:118355030chr19:6222697ENST00000389506+936301_3091406.03970.0DNA bindingNote=A.T hook 3
HgeneKMT2Achr11:118355030chr19:6222697ENST00000534358+936169_1801406.03973.0DNA bindingNote=A.T hook 1
HgeneKMT2Achr11:118355030chr19:6222697ENST00000534358+936217_2271406.03973.0DNA bindingNote=A.T hook 2
HgeneKMT2Achr11:118355030chr19:6222697ENST00000534358+936301_3091406.03973.0DNA bindingNote=A.T hook 3
HgeneKMT2Achr11:118355030chr19:6230726ENST00000354520+935169_1801406.03932.0DNA bindingNote=A.T hook 1
HgeneKMT2Achr11:118355030chr19:6230726ENST00000354520+935217_2271406.03932.0DNA bindingNote=A.T hook 2
HgeneKMT2Achr11:118355030chr19:6230726ENST00000354520+935301_3091406.03932.0DNA bindingNote=A.T hook 3
HgeneKMT2Achr11:118355030chr19:6230726ENST00000389506+936169_1801406.03970.0DNA bindingNote=A.T hook 1
HgeneKMT2Achr11:118355030chr19:6230726ENST00000389506+936217_2271406.03970.0DNA bindingNote=A.T hook 2
HgeneKMT2Achr11:118355030chr19:6230726ENST00000389506+936301_3091406.03970.0DNA bindingNote=A.T hook 3
HgeneKMT2Achr11:118355030chr19:6230726ENST00000534358+936169_1801406.03973.0DNA bindingNote=A.T hook 1
HgeneKMT2Achr11:118355030chr19:6230726ENST00000534358+936217_2271406.03973.0DNA bindingNote=A.T hook 2
HgeneKMT2Achr11:118355030chr19:6230726ENST00000534358+936301_3091406.03973.0DNA bindingNote=A.T hook 3
HgeneKMT2Achr11:118355690chr19:6270772ENST00000389506+1036169_1801444.03970.0DNA bindingNote=A.T hook 1
HgeneKMT2Achr11:118355690chr19:6270772ENST00000389506+1036217_2271444.03970.0DNA bindingNote=A.T hook 2
HgeneKMT2Achr11:118355690chr19:6270772ENST00000389506+1036301_3091444.03970.0DNA bindingNote=A.T hook 3
HgeneKMT2Achr11:118355690chr19:6270772ENST00000534358+1036169_1801444.03973.0DNA bindingNote=A.T hook 1
HgeneKMT2Achr11:118355690chr19:6270772ENST00000534358+1036217_2271444.03973.0DNA bindingNote=A.T hook 2
HgeneKMT2Achr11:118355690chr19:6270772ENST00000534358+1036301_3091444.03973.0DNA bindingNote=A.T hook 3
HgeneKMT2Achr11:118355691chr19:6222697ENST00000389506+1036169_1801444.03970.0DNA bindingNote=A.T hook 1
HgeneKMT2Achr11:118355691chr19:6222697ENST00000389506+1036217_2271444.03970.0DNA bindingNote=A.T hook 2
HgeneKMT2Achr11:118355691chr19:6222697ENST00000389506+1036301_3091444.03970.0DNA bindingNote=A.T hook 3
HgeneKMT2Achr11:118355691chr19:6222697ENST00000534358+1036169_1801444.03973.0DNA bindingNote=A.T hook 1
HgeneKMT2Achr11:118355691chr19:6222697ENST00000534358+1036217_2271444.03973.0DNA bindingNote=A.T hook 2
HgeneKMT2Achr11:118355691chr19:6222697ENST00000534358+1036301_3091444.03973.0DNA bindingNote=A.T hook 3
HgeneKMT2Achr11:118355030chr19:6222697ENST00000354520+935123_1341406.03932.0MotifIntegrase domain-binding motif 1 (IBM1)
HgeneKMT2Achr11:118355030chr19:6222697ENST00000354520+935147_1521406.03932.0MotifIntegrase domain-binding motif 2 (IBM2)
HgeneKMT2Achr11:118355030chr19:6222697ENST00000354520+9356_251406.03932.0MotifMenin-binding motif (MBM)
HgeneKMT2Achr11:118355030chr19:6222697ENST00000389506+936123_1341406.03970.0MotifIntegrase domain-binding motif 1 (IBM1)
HgeneKMT2Achr11:118355030chr19:6222697ENST00000389506+936147_1521406.03970.0MotifIntegrase domain-binding motif 2 (IBM2)
HgeneKMT2Achr11:118355030chr19:6222697ENST00000389506+9366_251406.03970.0MotifMenin-binding motif (MBM)
HgeneKMT2Achr11:118355030chr19:6222697ENST00000534358+936123_1341406.03973.0MotifIntegrase domain-binding motif 1 (IBM1)
HgeneKMT2Achr11:118355030chr19:6222697ENST00000534358+936147_1521406.03973.0MotifIntegrase domain-binding motif 2 (IBM2)
HgeneKMT2Achr11:118355030chr19:6222697ENST00000534358+9366_251406.03973.0MotifMenin-binding motif (MBM)
HgeneKMT2Achr11:118355030chr19:6230726ENST00000354520+935123_1341406.03932.0MotifIntegrase domain-binding motif 1 (IBM1)
HgeneKMT2Achr11:118355030chr19:6230726ENST00000354520+935147_1521406.03932.0MotifIntegrase domain-binding motif 2 (IBM2)
HgeneKMT2Achr11:118355030chr19:6230726ENST00000354520+9356_251406.03932.0MotifMenin-binding motif (MBM)
HgeneKMT2Achr11:118355030chr19:6230726ENST00000389506+936123_1341406.03970.0MotifIntegrase domain-binding motif 1 (IBM1)
HgeneKMT2Achr11:118355030chr19:6230726ENST00000389506+936147_1521406.03970.0MotifIntegrase domain-binding motif 2 (IBM2)
HgeneKMT2Achr11:118355030chr19:6230726ENST00000389506+9366_251406.03970.0MotifMenin-binding motif (MBM)
HgeneKMT2Achr11:118355030chr19:6230726ENST00000534358+936123_1341406.03973.0MotifIntegrase domain-binding motif 1 (IBM1)
HgeneKMT2Achr11:118355030chr19:6230726ENST00000534358+936147_1521406.03973.0MotifIntegrase domain-binding motif 2 (IBM2)
HgeneKMT2Achr11:118355030chr19:6230726ENST00000534358+9366_251406.03973.0MotifMenin-binding motif (MBM)
HgeneKMT2Achr11:118355690chr19:6270772ENST00000389506+1036123_1341444.03970.0MotifIntegrase domain-binding motif 1 (IBM1)
HgeneKMT2Achr11:118355690chr19:6270772ENST00000389506+1036147_1521444.03970.0MotifIntegrase domain-binding motif 2 (IBM2)
HgeneKMT2Achr11:118355690chr19:6270772ENST00000389506+10366_251444.03970.0MotifMenin-binding motif (MBM)
HgeneKMT2Achr11:118355690chr19:6270772ENST00000534358+1036123_1341444.03973.0MotifIntegrase domain-binding motif 1 (IBM1)
HgeneKMT2Achr11:118355690chr19:6270772ENST00000534358+1036147_1521444.03973.0MotifIntegrase domain-binding motif 2 (IBM2)
HgeneKMT2Achr11:118355690chr19:6270772ENST00000534358+10366_251444.03973.0MotifMenin-binding motif (MBM)
HgeneKMT2Achr11:118355691chr19:6222697ENST00000389506+1036123_1341444.03970.0MotifIntegrase domain-binding motif 1 (IBM1)
HgeneKMT2Achr11:118355691chr19:6222697ENST00000389506+1036147_1521444.03970.0MotifIntegrase domain-binding motif 2 (IBM2)
HgeneKMT2Achr11:118355691chr19:6222697ENST00000389506+10366_251444.03970.0MotifMenin-binding motif (MBM)
HgeneKMT2Achr11:118355691chr19:6222697ENST00000534358+1036123_1341444.03973.0MotifIntegrase domain-binding motif 1 (IBM1)
HgeneKMT2Achr11:118355691chr19:6222697ENST00000534358+1036147_1521444.03973.0MotifIntegrase domain-binding motif 2 (IBM2)
HgeneKMT2Achr11:118355691chr19:6222697ENST00000534358+10366_251444.03973.0MotifMenin-binding motif (MBM)
HgeneKMT2Achr11:118355030chr19:6222697ENST00000354520+9351147_11951406.03932.0Zinc fingerCXXC-type
HgeneKMT2Achr11:118355030chr19:6222697ENST00000389506+9361147_11951406.03970.0Zinc fingerCXXC-type
HgeneKMT2Achr11:118355030chr19:6222697ENST00000534358+9361147_11951406.03973.0Zinc fingerCXXC-type
HgeneKMT2Achr11:118355030chr19:6230726ENST00000354520+9351147_11951406.03932.0Zinc fingerCXXC-type
HgeneKMT2Achr11:118355030chr19:6230726ENST00000389506+9361147_11951406.03970.0Zinc fingerCXXC-type
HgeneKMT2Achr11:118355030chr19:6230726ENST00000534358+9361147_11951406.03973.0Zinc fingerCXXC-type
HgeneKMT2Achr11:118355690chr19:6270772ENST00000389506+10361147_11951444.03970.0Zinc fingerCXXC-type
HgeneKMT2Achr11:118355690chr19:6270772ENST00000534358+10361147_11951444.03973.0Zinc fingerCXXC-type
HgeneKMT2Achr11:118355691chr19:6222697ENST00000389506+10361147_11951444.03970.0Zinc fingerCXXC-type
HgeneKMT2Achr11:118355691chr19:6222697ENST00000534358+10361147_11951444.03973.0Zinc fingerCXXC-type
TgeneMLLT1chr11:118355030chr19:6222697ENST00000252674412272_280182.0560.0Compositional biasNote=Poly-Pro
TgeneMLLT1chr11:118355030chr19:6222697ENST00000252674412319_325182.0560.0Compositional biasNote=Poly-Ser
TgeneMLLT1chr11:118355030chr19:6222697ENST00000252674412374_389182.0560.0Compositional biasNote=Poly-Ser
TgeneMLLT1chr11:118355030chr19:6222697ENST00000252674412457_460182.0560.0Compositional biasNote=Poly-Pro
TgeneMLLT1chr11:118355030chr19:6222697ENST00000252674412463_466182.0560.0Compositional biasNote=Poly-Pro
TgeneMLLT1chr11:118355030chr19:6230726ENST00000252674212272_28092.0560.0Compositional biasNote=Poly-Pro
TgeneMLLT1chr11:118355030chr19:6230726ENST00000252674212319_32592.0560.0Compositional biasNote=Poly-Ser
TgeneMLLT1chr11:118355030chr19:6230726ENST00000252674212374_38992.0560.0Compositional biasNote=Poly-Ser
TgeneMLLT1chr11:118355030chr19:6230726ENST00000252674212457_46092.0560.0Compositional biasNote=Poly-Pro
TgeneMLLT1chr11:118355030chr19:6230726ENST00000252674212463_46692.0560.0Compositional biasNote=Poly-Pro
TgeneMLLT1chr11:118355690chr19:6270772ENST00000252674012272_2804.0560.0Compositional biasNote=Poly-Pro
TgeneMLLT1chr11:118355690chr19:6270772ENST00000252674012319_3254.0560.0Compositional biasNote=Poly-Ser
TgeneMLLT1chr11:118355690chr19:6270772ENST00000252674012374_3894.0560.0Compositional biasNote=Poly-Ser
TgeneMLLT1chr11:118355690chr19:6270772ENST00000252674012457_4604.0560.0Compositional biasNote=Poly-Pro
TgeneMLLT1chr11:118355690chr19:6270772ENST00000252674012463_4664.0560.0Compositional biasNote=Poly-Pro
TgeneMLLT1chr11:118355691chr19:6222697ENST00000252674412272_280182.0560.0Compositional biasNote=Poly-Pro
TgeneMLLT1chr11:118355691chr19:6222697ENST00000252674412319_325182.0560.0Compositional biasNote=Poly-Ser
TgeneMLLT1chr11:118355691chr19:6222697ENST00000252674412374_389182.0560.0Compositional biasNote=Poly-Ser
TgeneMLLT1chr11:118355691chr19:6222697ENST00000252674412457_460182.0560.0Compositional biasNote=Poly-Pro
TgeneMLLT1chr11:118355691chr19:6222697ENST00000252674412463_466182.0560.0Compositional biasNote=Poly-Pro
TgeneMLLT1chr11:118355690chr19:6270772ENST000002526740121_1384.0560.0DomainYEATS
TgeneMLLT1chr11:118355690chr19:6270772ENST0000025267401256_584.0560.0RegionAcylated histone binding
TgeneMLLT1chr11:118355690chr19:6270772ENST0000025267401278_804.0560.0RegionAcylated histone binding

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneKMT2Achr11:118355690chr19:6270772ENST00000354520+135137_1430.03932.0Compositional biasNote=Poly-Gly
HgeneKMT2Achr11:118355690chr19:6270772ENST00000354520+13517_1020.03932.0Compositional biasNote=Ala/Gly/Ser-rich
HgeneKMT2Achr11:118355690chr19:6270772ENST00000354520+135561_5640.03932.0Compositional biasNote=Poly-Pro
HgeneKMT2Achr11:118355690chr19:6270772ENST00000354520+135568_5710.03932.0Compositional biasNote=Poly-Pro
HgeneKMT2Achr11:118355691chr19:6222697ENST00000354520+135137_1430.03932.0Compositional biasNote=Poly-Gly
HgeneKMT2Achr11:118355691chr19:6222697ENST00000354520+13517_1020.03932.0Compositional biasNote=Ala/Gly/Ser-rich
HgeneKMT2Achr11:118355691chr19:6222697ENST00000354520+135561_5640.03932.0Compositional biasNote=Poly-Pro
HgeneKMT2Achr11:118355691chr19:6222697ENST00000354520+135568_5710.03932.0Compositional biasNote=Poly-Pro
HgeneKMT2Achr11:118355690chr19:6270772ENST00000354520+135169_1800.03932.0DNA bindingNote=A.T hook 1
HgeneKMT2Achr11:118355690chr19:6270772ENST00000354520+135217_2270.03932.0DNA bindingNote=A.T hook 2
HgeneKMT2Achr11:118355690chr19:6270772ENST00000354520+135301_3090.03932.0DNA bindingNote=A.T hook 3
HgeneKMT2Achr11:118355691chr19:6222697ENST00000354520+135169_1800.03932.0DNA bindingNote=A.T hook 1
HgeneKMT2Achr11:118355691chr19:6222697ENST00000354520+135217_2270.03932.0DNA bindingNote=A.T hook 2
HgeneKMT2Achr11:118355691chr19:6222697ENST00000354520+135301_3090.03932.0DNA bindingNote=A.T hook 3
HgeneKMT2Achr11:118355030chr19:6222697ENST00000354520+9351703_17481406.03932.0DomainBromo%3B divergent
HgeneKMT2Achr11:118355030chr19:6222697ENST00000354520+9352018_20741406.03932.0DomainFYR N-terminal
HgeneKMT2Achr11:118355030chr19:6222697ENST00000354520+9353666_37471406.03932.0DomainFYR C-terminal
HgeneKMT2Achr11:118355030chr19:6222697ENST00000354520+9353829_39451406.03932.0DomainSET
HgeneKMT2Achr11:118355030chr19:6222697ENST00000354520+9353953_39691406.03932.0DomainPost-SET
HgeneKMT2Achr11:118355030chr19:6222697ENST00000389506+9361703_17481406.03970.0DomainBromo%3B divergent
HgeneKMT2Achr11:118355030chr19:6222697ENST00000389506+9362018_20741406.03970.0DomainFYR N-terminal
HgeneKMT2Achr11:118355030chr19:6222697ENST00000389506+9363666_37471406.03970.0DomainFYR C-terminal
HgeneKMT2Achr11:118355030chr19:6222697ENST00000389506+9363829_39451406.03970.0DomainSET
HgeneKMT2Achr11:118355030chr19:6222697ENST00000389506+9363953_39691406.03970.0DomainPost-SET
HgeneKMT2Achr11:118355030chr19:6222697ENST00000534358+9361703_17481406.03973.0DomainBromo%3B divergent
HgeneKMT2Achr11:118355030chr19:6222697ENST00000534358+9362018_20741406.03973.0DomainFYR N-terminal
HgeneKMT2Achr11:118355030chr19:6222697ENST00000534358+9363666_37471406.03973.0DomainFYR C-terminal
HgeneKMT2Achr11:118355030chr19:6222697ENST00000534358+9363829_39451406.03973.0DomainSET
HgeneKMT2Achr11:118355030chr19:6222697ENST00000534358+9363953_39691406.03973.0DomainPost-SET
HgeneKMT2Achr11:118355030chr19:6230726ENST00000354520+9351703_17481406.03932.0DomainBromo%3B divergent
HgeneKMT2Achr11:118355030chr19:6230726ENST00000354520+9352018_20741406.03932.0DomainFYR N-terminal
HgeneKMT2Achr11:118355030chr19:6230726ENST00000354520+9353666_37471406.03932.0DomainFYR C-terminal
HgeneKMT2Achr11:118355030chr19:6230726ENST00000354520+9353829_39451406.03932.0DomainSET
HgeneKMT2Achr11:118355030chr19:6230726ENST00000354520+9353953_39691406.03932.0DomainPost-SET
HgeneKMT2Achr11:118355030chr19:6230726ENST00000389506+9361703_17481406.03970.0DomainBromo%3B divergent
HgeneKMT2Achr11:118355030chr19:6230726ENST00000389506+9362018_20741406.03970.0DomainFYR N-terminal
HgeneKMT2Achr11:118355030chr19:6230726ENST00000389506+9363666_37471406.03970.0DomainFYR C-terminal
HgeneKMT2Achr11:118355030chr19:6230726ENST00000389506+9363829_39451406.03970.0DomainSET
HgeneKMT2Achr11:118355030chr19:6230726ENST00000389506+9363953_39691406.03970.0DomainPost-SET
HgeneKMT2Achr11:118355030chr19:6230726ENST00000534358+9361703_17481406.03973.0DomainBromo%3B divergent
HgeneKMT2Achr11:118355030chr19:6230726ENST00000534358+9362018_20741406.03973.0DomainFYR N-terminal
HgeneKMT2Achr11:118355030chr19:6230726ENST00000534358+9363666_37471406.03973.0DomainFYR C-terminal
HgeneKMT2Achr11:118355030chr19:6230726ENST00000534358+9363829_39451406.03973.0DomainSET
HgeneKMT2Achr11:118355030chr19:6230726ENST00000534358+9363953_39691406.03973.0DomainPost-SET
HgeneKMT2Achr11:118355690chr19:6270772ENST00000354520+1351703_17480.03932.0DomainBromo%3B divergent
HgeneKMT2Achr11:118355690chr19:6270772ENST00000354520+1352018_20740.03932.0DomainFYR N-terminal
HgeneKMT2Achr11:118355690chr19:6270772ENST00000354520+1353666_37470.03932.0DomainFYR C-terminal
HgeneKMT2Achr11:118355690chr19:6270772ENST00000354520+1353829_39450.03932.0DomainSET
HgeneKMT2Achr11:118355690chr19:6270772ENST00000354520+1353953_39690.03932.0DomainPost-SET
HgeneKMT2Achr11:118355690chr19:6270772ENST00000389506+10361703_17481444.03970.0DomainBromo%3B divergent
HgeneKMT2Achr11:118355690chr19:6270772ENST00000389506+10362018_20741444.03970.0DomainFYR N-terminal
HgeneKMT2Achr11:118355690chr19:6270772ENST00000389506+10363666_37471444.03970.0DomainFYR C-terminal
HgeneKMT2Achr11:118355690chr19:6270772ENST00000389506+10363829_39451444.03970.0DomainSET
HgeneKMT2Achr11:118355690chr19:6270772ENST00000389506+10363953_39691444.03970.0DomainPost-SET
HgeneKMT2Achr11:118355690chr19:6270772ENST00000534358+10361703_17481444.03973.0DomainBromo%3B divergent
HgeneKMT2Achr11:118355690chr19:6270772ENST00000534358+10362018_20741444.03973.0DomainFYR N-terminal
HgeneKMT2Achr11:118355690chr19:6270772ENST00000534358+10363666_37471444.03973.0DomainFYR C-terminal
HgeneKMT2Achr11:118355690chr19:6270772ENST00000534358+10363829_39451444.03973.0DomainSET
HgeneKMT2Achr11:118355690chr19:6270772ENST00000534358+10363953_39691444.03973.0DomainPost-SET
HgeneKMT2Achr11:118355691chr19:6222697ENST00000354520+1351703_17480.03932.0DomainBromo%3B divergent
HgeneKMT2Achr11:118355691chr19:6222697ENST00000354520+1352018_20740.03932.0DomainFYR N-terminal
HgeneKMT2Achr11:118355691chr19:6222697ENST00000354520+1353666_37470.03932.0DomainFYR C-terminal
HgeneKMT2Achr11:118355691chr19:6222697ENST00000354520+1353829_39450.03932.0DomainSET
HgeneKMT2Achr11:118355691chr19:6222697ENST00000354520+1353953_39690.03932.0DomainPost-SET
HgeneKMT2Achr11:118355691chr19:6222697ENST00000389506+10361703_17481444.03970.0DomainBromo%3B divergent
HgeneKMT2Achr11:118355691chr19:6222697ENST00000389506+10362018_20741444.03970.0DomainFYR N-terminal
HgeneKMT2Achr11:118355691chr19:6222697ENST00000389506+10363666_37471444.03970.0DomainFYR C-terminal
HgeneKMT2Achr11:118355691chr19:6222697ENST00000389506+10363829_39451444.03970.0DomainSET
HgeneKMT2Achr11:118355691chr19:6222697ENST00000389506+10363953_39691444.03970.0DomainPost-SET
HgeneKMT2Achr11:118355691chr19:6222697ENST00000534358+10361703_17481444.03973.0DomainBromo%3B divergent
HgeneKMT2Achr11:118355691chr19:6222697ENST00000534358+10362018_20741444.03973.0DomainFYR N-terminal
HgeneKMT2Achr11:118355691chr19:6222697ENST00000534358+10363666_37471444.03973.0DomainFYR C-terminal
HgeneKMT2Achr11:118355691chr19:6222697ENST00000534358+10363829_39451444.03973.0DomainSET
HgeneKMT2Achr11:118355691chr19:6222697ENST00000534358+10363953_39691444.03973.0DomainPost-SET
HgeneKMT2Achr11:118355690chr19:6270772ENST00000354520+135123_1340.03932.0MotifIntegrase domain-binding motif 1 (IBM1)
HgeneKMT2Achr11:118355690chr19:6270772ENST00000354520+135147_1520.03932.0MotifIntegrase domain-binding motif 2 (IBM2)
HgeneKMT2Achr11:118355690chr19:6270772ENST00000354520+1356_250.03932.0MotifMenin-binding motif (MBM)
HgeneKMT2Achr11:118355691chr19:6222697ENST00000354520+135123_1340.03932.0MotifIntegrase domain-binding motif 1 (IBM1)
HgeneKMT2Achr11:118355691chr19:6222697ENST00000354520+135147_1520.03932.0MotifIntegrase domain-binding motif 2 (IBM2)
HgeneKMT2Achr11:118355691chr19:6222697ENST00000354520+1356_250.03932.0MotifMenin-binding motif (MBM)
HgeneKMT2Achr11:118355030chr19:6222697ENST00000354520+9353906_39071406.03932.0RegionS-adenosyl-L-methionine binding
HgeneKMT2Achr11:118355030chr19:6222697ENST00000389506+9363906_39071406.03970.0RegionS-adenosyl-L-methionine binding
HgeneKMT2Achr11:118355030chr19:6222697ENST00000534358+9363906_39071406.03973.0RegionS-adenosyl-L-methionine binding
HgeneKMT2Achr11:118355030chr19:6230726ENST00000354520+9353906_39071406.03932.0RegionS-adenosyl-L-methionine binding
HgeneKMT2Achr11:118355030chr19:6230726ENST00000389506+9363906_39071406.03970.0RegionS-adenosyl-L-methionine binding
HgeneKMT2Achr11:118355030chr19:6230726ENST00000534358+9363906_39071406.03973.0RegionS-adenosyl-L-methionine binding
HgeneKMT2Achr11:118355690chr19:6270772ENST00000354520+1353906_39070.03932.0RegionS-adenosyl-L-methionine binding
HgeneKMT2Achr11:118355690chr19:6270772ENST00000389506+10363906_39071444.03970.0RegionS-adenosyl-L-methionine binding
HgeneKMT2Achr11:118355690chr19:6270772ENST00000534358+10363906_39071444.03973.0RegionS-adenosyl-L-methionine binding
HgeneKMT2Achr11:118355691chr19:6222697ENST00000354520+1353906_39070.03932.0RegionS-adenosyl-L-methionine binding
HgeneKMT2Achr11:118355691chr19:6222697ENST00000389506+10363906_39071444.03970.0RegionS-adenosyl-L-methionine binding
HgeneKMT2Achr11:118355691chr19:6222697ENST00000534358+10363906_39071444.03973.0RegionS-adenosyl-L-methionine binding
HgeneKMT2Achr11:118355030chr19:6222697ENST00000354520+9351431_14821406.03932.0Zinc fingerPHD-type 1
HgeneKMT2Achr11:118355030chr19:6222697ENST00000354520+9351479_15331406.03932.0Zinc fingerPHD-type 2
HgeneKMT2Achr11:118355030chr19:6222697ENST00000354520+9351566_16271406.03932.0Zinc fingerPHD-type 3
HgeneKMT2Achr11:118355030chr19:6222697ENST00000354520+9351870_19101406.03932.0Zinc fingerC2HC pre-PHD-type
HgeneKMT2Achr11:118355030chr19:6222697ENST00000354520+9351931_19781406.03932.0Zinc fingerPHD-type 4
HgeneKMT2Achr11:118355030chr19:6222697ENST00000389506+9361431_14821406.03970.0Zinc fingerPHD-type 1
HgeneKMT2Achr11:118355030chr19:6222697ENST00000389506+9361479_15331406.03970.0Zinc fingerPHD-type 2
HgeneKMT2Achr11:118355030chr19:6222697ENST00000389506+9361566_16271406.03970.0Zinc fingerPHD-type 3
HgeneKMT2Achr11:118355030chr19:6222697ENST00000389506+9361870_19101406.03970.0Zinc fingerC2HC pre-PHD-type
HgeneKMT2Achr11:118355030chr19:6222697ENST00000389506+9361931_19781406.03970.0Zinc fingerPHD-type 4
HgeneKMT2Achr11:118355030chr19:6222697ENST00000534358+9361431_14821406.03973.0Zinc fingerPHD-type 1
HgeneKMT2Achr11:118355030chr19:6222697ENST00000534358+9361479_15331406.03973.0Zinc fingerPHD-type 2
HgeneKMT2Achr11:118355030chr19:6222697ENST00000534358+9361566_16271406.03973.0Zinc fingerPHD-type 3
HgeneKMT2Achr11:118355030chr19:6222697ENST00000534358+9361870_19101406.03973.0Zinc fingerC2HC pre-PHD-type
HgeneKMT2Achr11:118355030chr19:6222697ENST00000534358+9361931_19781406.03973.0Zinc fingerPHD-type 4
HgeneKMT2Achr11:118355030chr19:6230726ENST00000354520+9351431_14821406.03932.0Zinc fingerPHD-type 1
HgeneKMT2Achr11:118355030chr19:6230726ENST00000354520+9351479_15331406.03932.0Zinc fingerPHD-type 2
HgeneKMT2Achr11:118355030chr19:6230726ENST00000354520+9351566_16271406.03932.0Zinc fingerPHD-type 3
HgeneKMT2Achr11:118355030chr19:6230726ENST00000354520+9351870_19101406.03932.0Zinc fingerC2HC pre-PHD-type
HgeneKMT2Achr11:118355030chr19:6230726ENST00000354520+9351931_19781406.03932.0Zinc fingerPHD-type 4
HgeneKMT2Achr11:118355030chr19:6230726ENST00000389506+9361431_14821406.03970.0Zinc fingerPHD-type 1
HgeneKMT2Achr11:118355030chr19:6230726ENST00000389506+9361479_15331406.03970.0Zinc fingerPHD-type 2
HgeneKMT2Achr11:118355030chr19:6230726ENST00000389506+9361566_16271406.03970.0Zinc fingerPHD-type 3
HgeneKMT2Achr11:118355030chr19:6230726ENST00000389506+9361870_19101406.03970.0Zinc fingerC2HC pre-PHD-type
HgeneKMT2Achr11:118355030chr19:6230726ENST00000389506+9361931_19781406.03970.0Zinc fingerPHD-type 4
HgeneKMT2Achr11:118355030chr19:6230726ENST00000534358+9361431_14821406.03973.0Zinc fingerPHD-type 1
HgeneKMT2Achr11:118355030chr19:6230726ENST00000534358+9361479_15331406.03973.0Zinc fingerPHD-type 2
HgeneKMT2Achr11:118355030chr19:6230726ENST00000534358+9361566_16271406.03973.0Zinc fingerPHD-type 3
HgeneKMT2Achr11:118355030chr19:6230726ENST00000534358+9361870_19101406.03973.0Zinc fingerC2HC pre-PHD-type
HgeneKMT2Achr11:118355030chr19:6230726ENST00000534358+9361931_19781406.03973.0Zinc fingerPHD-type 4
HgeneKMT2Achr11:118355690chr19:6270772ENST00000354520+1351147_11950.03932.0Zinc fingerCXXC-type
HgeneKMT2Achr11:118355690chr19:6270772ENST00000354520+1351431_14820.03932.0Zinc fingerPHD-type 1
HgeneKMT2Achr11:118355690chr19:6270772ENST00000354520+1351479_15330.03932.0Zinc fingerPHD-type 2
HgeneKMT2Achr11:118355690chr19:6270772ENST00000354520+1351566_16270.03932.0Zinc fingerPHD-type 3
HgeneKMT2Achr11:118355690chr19:6270772ENST00000354520+1351870_19100.03932.0Zinc fingerC2HC pre-PHD-type
HgeneKMT2Achr11:118355690chr19:6270772ENST00000354520+1351931_19780.03932.0Zinc fingerPHD-type 4
HgeneKMT2Achr11:118355690chr19:6270772ENST00000389506+10361431_14821444.03970.0Zinc fingerPHD-type 1
HgeneKMT2Achr11:118355690chr19:6270772ENST00000389506+10361479_15331444.03970.0Zinc fingerPHD-type 2
HgeneKMT2Achr11:118355690chr19:6270772ENST00000389506+10361566_16271444.03970.0Zinc fingerPHD-type 3
HgeneKMT2Achr11:118355690chr19:6270772ENST00000389506+10361870_19101444.03970.0Zinc fingerC2HC pre-PHD-type
HgeneKMT2Achr11:118355690chr19:6270772ENST00000389506+10361931_19781444.03970.0Zinc fingerPHD-type 4
HgeneKMT2Achr11:118355690chr19:6270772ENST00000534358+10361431_14821444.03973.0Zinc fingerPHD-type 1
HgeneKMT2Achr11:118355690chr19:6270772ENST00000534358+10361479_15331444.03973.0Zinc fingerPHD-type 2
HgeneKMT2Achr11:118355690chr19:6270772ENST00000534358+10361566_16271444.03973.0Zinc fingerPHD-type 3
HgeneKMT2Achr11:118355690chr19:6270772ENST00000534358+10361870_19101444.03973.0Zinc fingerC2HC pre-PHD-type
HgeneKMT2Achr11:118355690chr19:6270772ENST00000534358+10361931_19781444.03973.0Zinc fingerPHD-type 4
HgeneKMT2Achr11:118355691chr19:6222697ENST00000354520+1351147_11950.03932.0Zinc fingerCXXC-type
HgeneKMT2Achr11:118355691chr19:6222697ENST00000354520+1351431_14820.03932.0Zinc fingerPHD-type 1
HgeneKMT2Achr11:118355691chr19:6222697ENST00000354520+1351479_15330.03932.0Zinc fingerPHD-type 2
HgeneKMT2Achr11:118355691chr19:6222697ENST00000354520+1351566_16270.03932.0Zinc fingerPHD-type 3
HgeneKMT2Achr11:118355691chr19:6222697ENST00000354520+1351870_19100.03932.0Zinc fingerC2HC pre-PHD-type
HgeneKMT2Achr11:118355691chr19:6222697ENST00000354520+1351931_19780.03932.0Zinc fingerPHD-type 4
HgeneKMT2Achr11:118355691chr19:6222697ENST00000389506+10361431_14821444.03970.0Zinc fingerPHD-type 1
HgeneKMT2Achr11:118355691chr19:6222697ENST00000389506+10361479_15331444.03970.0Zinc fingerPHD-type 2
HgeneKMT2Achr11:118355691chr19:6222697ENST00000389506+10361566_16271444.03970.0Zinc fingerPHD-type 3
HgeneKMT2Achr11:118355691chr19:6222697ENST00000389506+10361870_19101444.03970.0Zinc fingerC2HC pre-PHD-type
HgeneKMT2Achr11:118355691chr19:6222697ENST00000389506+10361931_19781444.03970.0Zinc fingerPHD-type 4
HgeneKMT2Achr11:118355691chr19:6222697ENST00000534358+10361431_14821444.03973.0Zinc fingerPHD-type 1
HgeneKMT2Achr11:118355691chr19:6222697ENST00000534358+10361479_15331444.03973.0Zinc fingerPHD-type 2
HgeneKMT2Achr11:118355691chr19:6222697ENST00000534358+10361566_16271444.03973.0Zinc fingerPHD-type 3
HgeneKMT2Achr11:118355691chr19:6222697ENST00000534358+10361870_19101444.03973.0Zinc fingerC2HC pre-PHD-type
HgeneKMT2Achr11:118355691chr19:6222697ENST00000534358+10361931_19781444.03973.0Zinc fingerPHD-type 4
TgeneMLLT1chr11:118355030chr19:6222697ENST000002526744121_138182.0560.0DomainYEATS
TgeneMLLT1chr11:118355030chr19:6230726ENST000002526742121_13892.0560.0DomainYEATS
TgeneMLLT1chr11:118355691chr19:6222697ENST000002526744121_138182.0560.0DomainYEATS
TgeneMLLT1chr11:118355030chr19:6222697ENST0000025267441256_58182.0560.0RegionAcylated histone binding
TgeneMLLT1chr11:118355030chr19:6222697ENST0000025267441278_80182.0560.0RegionAcylated histone binding
TgeneMLLT1chr11:118355030chr19:6230726ENST0000025267421256_5892.0560.0RegionAcylated histone binding
TgeneMLLT1chr11:118355030chr19:6230726ENST0000025267421278_8092.0560.0RegionAcylated histone binding
TgeneMLLT1chr11:118355691chr19:6222697ENST0000025267441256_58182.0560.0RegionAcylated histone binding
TgeneMLLT1chr11:118355691chr19:6222697ENST0000025267441278_80182.0560.0RegionAcylated histone binding


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Fusion Gene Sequence for KMT2A-MLLT1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000534358_ENST00000252674_AY040555_KMT2A_chr11_118355030_+_MLLT1_chr19_6230726_length(transcript)=5732nt_BP=4241nt
CTGCTTCACTTCACGGGGCGAACATGGCGCACAGCTGTCGGTGGCGCTTCCCCGCCCGACCCGGGACCACCGGGGGCGGCGGCGGCGGGG
GGCGCCGGGGCCTAGGGGGCGCCCCGCGGCAACGCGTCCCGGCCCTGCTGCTTCCCCCCGGGCCCCCGGTCGGCGGTGGCGGCCCCGGGG
CGCCCCCCTCCCCCCCGGCTGTGGCGGCCGCGGCGGCGGCGGCGGGAAGCAGCGGGGCTGGGGTTCCAGGGGGAGCGGCCGCCGCCTCAG
CAGCCTCCTCGTCGTCCGCCTCGTCTTCGTCTTCGTCATCGTCCTCAGCCTCTTCAGGGCCGGCCCTGCTCCGGGTGGGCCCGGGCTTCG
ACGCGGCGCTGCAGGTCTCGGCCGCCATCGGCACCAACCTGCGCCGGTTCCGGGCCGTGTTTGGGGAGAGCGGCGGGGGAGGCGGCAGCG
GAGAGGATGAGCAATTCTTAGGTTTTGGCTCAGATGAAGAAGTCAGAGTGCGAAGTCCCACAAGGTCTCCTTCAGTTAAAACTAGTCCTC
GAAAACCTCGTGGGAGACCTAGAAGTGGCTCTGACCGAAATTCAGCTATCCTCTCAGATCCATCTGTGTTTTCCCCTCTAAATAAATCAG
AGACCAAATCTGGAGATAAGATCAAGAAGAAAGATTCTAAAAGTATAGAAAAGAAGAGAGGAAGACCTCCCACCTTCCCTGGAGTAAAAA
TCAAAATAACACATGGAAAGGACATTTCAGAGTTACCAAAGGGAAACAAAGAAGATAGCCTGAAAAAAATTAAAAGGACACCTTCTGCTA
CGTTTCAGCAAGCCACAAAGATTAAAAAATTAAGAGCAGGTAAACTCTCTCCTCTCAAGTCTAAGTTTAAGACAGGGAAGCTTCAAATAG
GAAGGAAGGGGGTACAAATTGTACGACGGAGAGGAAGGCCTCCATCAACAGAAAGGATAAAGACCCCTTCGGGTCTCCTCATTAATTCTG
AACTGGAAAAGCCCCAGAAAGTCCGGAAAGACAAGGAAGGAACACCTCCACTTACAAAAGAAGATAAGACAGTTGTCAGACAAAGCCCTC
GAAGGATTAAGCCAGTTAGGATTATTCCTTCTTCAAAAAGGACAGATGCAACCATTGCTAAGCAACTCTTACAGAGGGCAAAAAAGGGGG
CTCAAAAGAAAATTGAAAAAGAAGCAGCTCAGCTGCAGGGAAGAAAGGTGAAGACACAGGTCAAAAATATTCGACAGTTCATCATGCCTG
TTGTCAGTGCTATCTCCTCGCGGATCATTAAGACCCCTCGGCGGTTTATAGAGGATGAGGATTATGACCCTCCAATTAAAATTGCCCGAT
TAGAGTCTACACCGAATAGTAGATTCAGTGCCCCGTCCTGTGGATCTTCTGAAAAATCAAGTGCAGCTTCTCAGCACTCCTCTCAAATGT
CTTCAGACTCCTCTCGATCTAGTAGCCCCAGTGTTGATACCTCCACAGACTCTCAGGCTTCTGAGGAGATTCAGGTACTTCCTGAGGAGC
GGAGCGATACCCCTGAAGTTCATCCTCCACTGCCCATTTCCCAGTCCCCAGAAAATGAGAGTAATGATAGGAGAAGCAGAAGGTATTCAG
TGTCGGAGAGAAGTTTTGGATCTAGAACGACGAAAAAATTATCAACTCTACAAAGTGCCCCCCAGCAGCAGACCTCCTCGTCTCCACCTC
CACCTCTGCTGACTCCACCGCCACCACTGCAGCCAGCCTCCAGTATCTCTGACCACACACCTTGGCTTATGCCTCCAACAATCCCCTTAG
CATCACCATTTTTGCCTGCTTCCACTGCTCCTATGCAAGGGAAGCGAAAATCTATTTTGCGAGAACCGACATTTAGGTGGACTTCTTTAA
AGCATTCTAGGTCAGAGCCACAATACTTTTCCTCAGCAAAGTATGCCAAAGAAGGTCTTATTCGCAAACCAATATTTGATAATTTCCGAC
CCCCTCCACTAACTCCCGAGGACGTTGGCTTTGCATCTGGTTTTTCTGCATCTGGTACCGCTGCTTCAGCCCGATTGTTTTCGCCACTCC
ATTCTGGAACAAGGTTTGATATGCACAAAAGGAGCCCTCTTCTGAGAGCTCCAAGATTTACTCCAAGTGAGGCTCACTCTAGAATATTTG
AGTCTGTAACCTTGCCTAGTAATCGAACTTCTGCTGGAACATCTTCTTCAGGAGTATCCAATAGAAAAAGGAAAAGAAAAGTGTTTAGTC
CTATTCGATCTGAACCAAGATCTCCTTCTCACTCCATGAGGACAAGAAGTGGAAGGCTTAGTAGTTCTGAGCTCTCACCTCTCACCCCCC
CGTCTTCTGTCTCTTCCTCGTTAAGCATTTCTGTTAGTCCTCTTGCCACTAGTGCCTTAAACCCAACTTTTACTTTTCCTTCTCATTCCC
TGACTCAGTCTGGGGAATCTGCAGAGAAAAATCAGAGACCAAGGAAGCAGACTAGTGCTCCGGCAGAGCCATTTTCATCAAGTAGTCCTA
CTCCTCTCTTCCCTTGGTTTACCCCAGGCTCTCAGACTGAAAGAGGGAGAAATAAAGACAAGGCCCCCGAGGAGCTGTCCAAAGATCGAG
ATGCTGACAAGAGCGTGGAGAAGGACAAGAGTAGAGAGAGAGACCGGGAGAGAGAAAAGGAGAATAAGCGGGAGTCAAGGAAAGAGAAAA
GGAAAAAGGGATCAGAAATTCAGAGTAGTTCTGCTTTGTATCCTGTGGGTAGGGTTTCCAAAGAGAAGGTTGTTGGTGAAGATGTTGCCA
CTTCATCTTCTGCCAAAAAAGCAACAGGGCGGAAGAAGTCTTCATCACATGATTCTGGGACTGATATTACTTCTGTGACTCTTGGGGATA
CAACAGCTGTCAAAACCAAAATACTTATAAAGAAAGGGAGAGGAAATCTGGAAAAAACCAACTTGGACCTCGGCCCAACTGCCCCATCCC
TGGAGAAGGAGAAAACCCTCTGCCTTTCCACTCCTTCATCTAGCACTGTTAAACATTCCACTTCCTCCATAGGCTCCATGTTGGCTCAGG
CAGACAAGCTTCCAATGACTGACAAGAGGGTTGCCAGCCTCCTAAAAAAGGCCAAAGCTCAGCTCTGCAAGATTGAGAAGAGTAAGAGTC
TTAAACAAACCGACCAGCCCAAAGCACAGGGTCAAGAAAGTGACTCATCAGAGACCTCTGTGCGAGGACCCCGGATTAAACATGTCTGCA
GAAGAGCAGCTGTTGCCCTTGGCCGAAAACGAGCTGTGTTTCCTGATGACATGCCCACCCTGAGTGCCTTACCATGGGAAGAACGAGAAA
AGATTTTGTCTTCCATGGGGAATGATGACAAGTCATCAATTGCTGGCTCAGAAGATGCTGAACCTCTTGCTCCACCCATCAAACCAATTA
AACCTGTCACTAGAAACAAGGCACCCCAGGAACCTCCAGTAAAGAAAGGACGTCGATCGAGGCGGTGTGGGCAGTGTCCCGGCTGCCAGG
TGCCTGAGGACTGTGGTGTTTGTACTAATTGCTTAGATAAGCCCAAGTTTGGTGGTCGCAATATAAAGAAGCAGTGCTGCAAGATGAGAA
AATGTCAGAATCTACAATGGATGCCTTCCAAAGCCTACCTGCAGAAGCAAGCTAAAGCTGTGAAAAAGAAAGAGAAAAAGTCTAAGACCA
GTGAAAAGAAAGACAGCAAAGAGAGCAGTGTTGTGAAGAACGTGGTGGACTCTAGTCAGAAACCTACCCCATCAGCAAGAGAGGATCCTG
CCCCAAAGAAAAGCAGTAGTGAGCCTCCTCCACGAAAGCCCGTCGAGGAAAAGAGTGAAGAAGGGAATGTCTCGGCCCCTGGGCCTGAAT
CCAAACAGGCCACCACTCCAGCTTCCAGGAAGTCAAGCAAGCAGGTCTCCCAGCCAGCACTGGTCATCCCGCCTCAGCCACCTACTACAG
GACCGCCAAGAAAAGAAGTTCCCAAAACCACTCCTAGTGAGCCCAAGAAAAAGCAGCCTCCACCACCAGAATCAGGTCCAGAGCAGAGCA
AACAGAAAAAAGTGGCTCCCCGCCCAAGTATCCCTGTAAAACAAAAACCAAAAGAAAAGGAAAAACCACCTCCGGTCAATAAGCAGGAGA
ATGCAGGCACTTTGAACATCCTCAGCACTCTCTCCAATGGCAATAGTTCTAAGCAAAAAATTCCAGCAGATGGAGTCCACAGGATCAGAG
TGGACTTTAAGGAGGAGCCGAGGAAGGTCTGCTTCACCTACGACCTGTTCCTGAACCTGGAAGGCAACCCGCCCGTGAACCACCTGCGCT
GCGAGAAGCTCACCTTCAACAACCCCACCACGGAGTTCCGGTACAAGCTCCTGCGGGCCGGCGGGGTGATGGTAATGCCCGAAGGAGCAG
ACACGGTGTCCAGGCCCAGTCCCGACTACCCCATGTTACCCACAATTCCACTCTCTGCCTTCTCTGACCCCAAGAAGACCAAACCATCCC
ACGGCTCCAAGGACGCCAACAAGGAGAGCAGCAAGACCTCCAAGCCACACAAGGTGACCAAGGAGCACCGGGAGCGGCCCCGCAAAGACT
CCGAGAGCAAGAGCTCCTCCAAGGAGCTGGAGCGTGAGCAGGCCAAAAGCTCCAAGGACACCTCGCGGAAGCTGGGCGAGGGCCGGCTGC
CCAAGGAGGAGAAGGCGCCACCGCCCAAGGCTGCCTTCAAGGAACCCAAGATGGCCCTGAAAGAGACCAAGCTGGAAAGCACGTCCCCCA
AGGGTGGGCCCCCACCCCCACCCCCACCCCCACCCCGGGCTTCCAGCAAGCGGCCGGCCACCGCCGACTCGCCAAAGCCCAGCGCCAAGA
AGCAGAAGAAGAGCAGCTCGAAGGGGTCCCGGAGTGCTCCAGGCACCTCGCCCCGCACCTCCTCCTCCTCCTCCTTCTCGGACAAGAAGC
CGGCCAAGGACAAGAGCAGCACCAGAGGGGAGAAGGTGAAGGCCGAGAGTGAGCCCCGGGAGGCCAAAAAGGCCCTGGAGGTGGAGGAGT
CCAACTCAGAGGACGAGGCCTCCTTCAAGTCCGAGTCTGCCCAGTCAAGCCCGTCCAACTCCAGCTCCAGCTCAGACTCCAGCTCAGACT
CAGACTTCGAGCCATCCCAGAACCACAGCCAAGGACCCCTGCGCTCCATGGTGGAGGACCTGCAGTCCGAGGAGTCCGACGAGGACGACT
CTTCGTCAGGCGAGGAGGCTGCCGGCAAGACCAACCCGGGGAGGGACTCCAGGTTGAGCTTCAGCGACAGCGAGAGTGACAACAGCGCCG
ACTCCTCCCTGCCCAGCCGTGAGCCCCCACCCCCCCAGAAGCCACCCCCGCCCAACAGCAAGGTGTCAGGCCGGAGGAGCCCCGAGTCCT
GCAGCAAGCCTGAGAAGATCCTCAAGAAGGGCACCTACGACAAGGCCTACACGGATGAGCTGGTGGAGCTACACCGGAGGCTGATGGCGC
TGCGGGAGCGCAACGTGCTGCAGCAGATTGTGAATCTGATCGAGGAGACTGGCCACTTCAATGTCACCAACACCACCTTCGACTTCGACC
TCTTCTCCCTGGACGAGACCACCGTGCGCAAACTGCAGAGCTGCCTGGAGGCCGTGGCCACATGACCCTGGGCCGCGTGCCGGGCCCCCA

>In-frame_ENST00000534358_ENST00000252674_AY040555_KMT2A_chr11_118355030_+_MLLT1_chr19_6230726_length(amino acids)=1873AA_start in transcript=23_stop in transcript=5644
MAHSCRWRFPARPGTTGGGGGGGRRGLGGAPRQRVPALLLPPGPPVGGGGPGAPPSPPAVAAAAAAAGSSGAGVPGGAAAASAASSSSAS
SSSSSSSSASSGPALLRVGPGFDAALQVSAAIGTNLRRFRAVFGESGGGGGSGEDEQFLGFGSDEEVRVRSPTRSPSVKTSPRKPRGRPR
SGSDRNSAILSDPSVFSPLNKSETKSGDKIKKKDSKSIEKKRGRPPTFPGVKIKITHGKDISELPKGNKEDSLKKIKRTPSATFQQATKI
KKLRAGKLSPLKSKFKTGKLQIGRKGVQIVRRRGRPPSTERIKTPSGLLINSELEKPQKVRKDKEGTPPLTKEDKTVVRQSPRRIKPVRI
IPSSKRTDATIAKQLLQRAKKGAQKKIEKEAAQLQGRKVKTQVKNIRQFIMPVVSAISSRIIKTPRRFIEDEDYDPPIKIARLESTPNSR
FSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGS
RTTKKLSTLQSAPQQQTSSSPPPPLLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQ
YFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSN
RTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESA
EKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQ
SSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKILIKKGRGNLEKTNLDLGPTAPSLEKEKTLC
LSTPSSSTVKHSTSSIGSMLAQADKLPMTDKRVASLLKKAKAQLCKIEKSKSLKQTDQPKAQGQESDSSETSVRGPRIKHVCRRAAVALG
RKRAVFPDDMPTLSALPWEEREKILSSMGNDDKSSIAGSEDAEPLAPPIKPIKPVTRNKAPQEPPVKKGRRSRRCGQCPGCQVPEDCGVC
TNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKSSSE
PPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPR
PSIPVKQKPKEKEKPPPVNKQENAGTLNILSTLSNGNSSKQKIPADGVHRIRVDFKEEPRKVCFTYDLFLNLEGNPPVNHLRCEKLTFNN
PTTEFRYKLLRAGGVMVMPEGADTVSRPSPDYPMLPTIPLSAFSDPKKTKPSHGSKDANKESSKTSKPHKVTKEHRERPRKDSESKSSSK
ELEREQAKSSKDTSRKLGEGRLPKEEKAPPPKAAFKEPKMALKETKLESTSPKGGPPPPPPPPPRASSKRPATADSPKPSAKKQKKSSSK
GSRSAPGTSPRTSSSSSFSDKKPAKDKSSTRGEKVKAESEPREAKKALEVEESNSEDEASFKSESAQSSPSNSSSSSDSSSDSDFEPSQN
HSQGPLRSMVEDLQSEESDEDDSSSGEEAAGKTNPGRDSRLSFSDSESDNSADSSLPSREPPPPQKPPPPNSKVSGRRSPESCSKPEKIL

--------------------------------------------------------------
>In-frame_ENST00000389506_ENST00000252674_AY040555_KMT2A_chr11_118355030_+_MLLT1_chr19_6230726_length(transcript)=5709nt_BP=4218nt
ATGGCGCACAGCTGTCGGTGGCGCTTCCCCGCCCGACCCGGGACCACCGGGGGCGGCGGCGGCGGGGGGCGCCGGGGCCTAGGGGGCGCC
CCGCGGCAACGCGTCCCGGCCCTGCTGCTTCCCCCCGGGCCCCCGGTCGGCGGTGGCGGCCCCGGGGCGCCCCCCTCCCCCCCGGCTGTG
GCGGCCGCGGCGGCGGCGGCGGGAAGCAGCGGGGCTGGGGTTCCAGGGGGAGCGGCCGCCGCCTCAGCAGCCTCCTCGTCGTCCGCCTCG
TCTTCGTCTTCGTCATCGTCCTCAGCCTCTTCAGGGCCGGCCCTGCTCCGGGTGGGCCCGGGCTTCGACGCGGCGCTGCAGGTCTCGGCC
GCCATCGGCACCAACCTGCGCCGGTTCCGGGCCGTGTTTGGGGAGAGCGGCGGGGGAGGCGGCAGCGGAGAGGATGAGCAATTCTTAGGT
TTTGGCTCAGATGAAGAAGTCAGAGTGCGAAGTCCCACAAGGTCTCCTTCAGTTAAAACTAGTCCTCGAAAACCTCGTGGGAGACCTAGA
AGTGGCTCTGACCGAAATTCAGCTATCCTCTCAGATCCATCTGTGTTTTCCCCTCTAAATAAATCAGAGACCAAATCTGGAGATAAGATC
AAGAAGAAAGATTCTAAAAGTATAGAAAAGAAGAGAGGAAGACCTCCCACCTTCCCTGGAGTAAAAATCAAAATAACACATGGAAAGGAC
ATTTCAGAGTTACCAAAGGGAAACAAAGAAGATAGCCTGAAAAAAATTAAAAGGACACCTTCTGCTACGTTTCAGCAAGCCACAAAGATT
AAAAAATTAAGAGCAGGTAAACTCTCTCCTCTCAAGTCTAAGTTTAAGACAGGGAAGCTTCAAATAGGAAGGAAGGGGGTACAAATTGTA
CGACGGAGAGGAAGGCCTCCATCAACAGAAAGGATAAAGACCCCTTCGGGTCTCCTCATTAATTCTGAACTGGAAAAGCCCCAGAAAGTC
CGGAAAGACAAGGAAGGAACACCTCCACTTACAAAAGAAGATAAGACAGTTGTCAGACAAAGCCCTCGAAGGATTAAGCCAGTTAGGATT
ATTCCTTCTTCAAAAAGGACAGATGCAACCATTGCTAAGCAACTCTTACAGAGGGCAAAAAAGGGGGCTCAAAAGAAAATTGAAAAAGAA
GCAGCTCAGCTGCAGGGAAGAAAGGTGAAGACACAGGTCAAAAATATTCGACAGTTCATCATGCCTGTTGTCAGTGCTATCTCCTCGCGG
ATCATTAAGACCCCTCGGCGGTTTATAGAGGATGAGGATTATGACCCTCCAATTAAAATTGCCCGATTAGAGTCTACACCGAATAGTAGA
TTCAGTGCCCCGTCCTGTGGATCTTCTGAAAAATCAAGTGCAGCTTCTCAGCACTCCTCTCAAATGTCTTCAGACTCCTCTCGATCTAGT
AGCCCCAGTGTTGATACCTCCACAGACTCTCAGGCTTCTGAGGAGATTCAGGTACTTCCTGAGGAGCGGAGCGATACCCCTGAAGTTCAT
CCTCCACTGCCCATTTCCCAGTCCCCAGAAAATGAGAGTAATGATAGGAGAAGCAGAAGGTATTCAGTGTCGGAGAGAAGTTTTGGATCT
AGAACGACGAAAAAATTATCAACTCTACAAAGTGCCCCCCAGCAGCAGACCTCCTCGTCTCCACCTCCACCTCTGCTGACTCCACCGCCA
CCACTGCAGCCAGCCTCCAGTATCTCTGACCACACACCTTGGCTTATGCCTCCAACAATCCCCTTAGCATCACCATTTTTGCCTGCTTCC
ACTGCTCCTATGCAAGGGAAGCGAAAATCTATTTTGCGAGAACCGACATTTAGGTGGACTTCTTTAAAGCATTCTAGGTCAGAGCCACAA
TACTTTTCCTCAGCAAAGTATGCCAAAGAAGGTCTTATTCGCAAACCAATATTTGATAATTTCCGACCCCCTCCACTAACTCCCGAGGAC
GTTGGCTTTGCATCTGGTTTTTCTGCATCTGGTACCGCTGCTTCAGCCCGATTGTTTTCGCCACTCCATTCTGGAACAAGGTTTGATATG
CACAAAAGGAGCCCTCTTCTGAGAGCTCCAAGATTTACTCCAAGTGAGGCTCACTCTAGAATATTTGAGTCTGTAACCTTGCCTAGTAAT
CGAACTTCTGCTGGAACATCTTCTTCAGGAGTATCCAATAGAAAAAGGAAAAGAAAAGTGTTTAGTCCTATTCGATCTGAACCAAGATCT
CCTTCTCACTCCATGAGGACAAGAAGTGGAAGGCTTAGTAGTTCTGAGCTCTCACCTCTCACCCCCCCGTCTTCTGTCTCTTCCTCGTTA
AGCATTTCTGTTAGTCCTCTTGCCACTAGTGCCTTAAACCCAACTTTTACTTTTCCTTCTCATTCCCTGACTCAGTCTGGGGAATCTGCA
GAGAAAAATCAGAGACCAAGGAAGCAGACTAGTGCTCCGGCAGAGCCATTTTCATCAAGTAGTCCTACTCCTCTCTTCCCTTGGTTTACC
CCAGGCTCTCAGACTGAAAGAGGGAGAAATAAAGACAAGGCCCCCGAGGAGCTGTCCAAAGATCGAGATGCTGACAAGAGCGTGGAGAAG
GACAAGAGTAGAGAGAGAGACCGGGAGAGAGAAAAGGAGAATAAGCGGGAGTCAAGGAAAGAGAAAAGGAAAAAGGGATCAGAAATTCAG
AGTAGTTCTGCTTTGTATCCTGTGGGTAGGGTTTCCAAAGAGAAGGTTGTTGGTGAAGATGTTGCCACTTCATCTTCTGCCAAAAAAGCA
ACAGGGCGGAAGAAGTCTTCATCACATGATTCTGGGACTGATATTACTTCTGTGACTCTTGGGGATACAACAGCTGTCAAAACCAAAATA
CTTATAAAGAAAGGGAGAGGAAATCTGGAAAAAACCAACTTGGACCTCGGCCCAACTGCCCCATCCCTGGAGAAGGAGAAAACCCTCTGC
CTTTCCACTCCTTCATCTAGCACTGTTAAACATTCCACTTCCTCCATAGGCTCCATGTTGGCTCAGGCAGACAAGCTTCCAATGACTGAC
AAGAGGGTTGCCAGCCTCCTAAAAAAGGCCAAAGCTCAGCTCTGCAAGATTGAGAAGAGTAAGAGTCTTAAACAAACCGACCAGCCCAAA
GCACAGGGTCAAGAAAGTGACTCATCAGAGACCTCTGTGCGAGGACCCCGGATTAAACATGTCTGCAGAAGAGCAGCTGTTGCCCTTGGC
CGAAAACGAGCTGTGTTTCCTGATGACATGCCCACCCTGAGTGCCTTACCATGGGAAGAACGAGAAAAGATTTTGTCTTCCATGGGGAAT
GATGACAAGTCATCAATTGCTGGCTCAGAAGATGCTGAACCTCTTGCTCCACCCATCAAACCAATTAAACCTGTCACTAGAAACAAGGCA
CCCCAGGAACCTCCAGTAAAGAAAGGACGTCGATCGAGGCGGTGTGGGCAGTGTCCCGGCTGCCAGGTGCCTGAGGACTGTGGTGTTTGT
ACTAATTGCTTAGATAAGCCCAAGTTTGGTGGTCGCAATATAAAGAAGCAGTGCTGCAAGATGAGAAAATGTCAGAATCTACAATGGATG
CCTTCCAAAGCCTACCTGCAGAAGCAAGCTAAAGCTGTGAAAAAGAAAGAGAAAAAGTCTAAGACCAGTGAAAAGAAAGACAGCAAAGAG
AGCAGTGTTGTGAAGAACGTGGTGGACTCTAGTCAGAAACCTACCCCATCAGCAAGAGAGGATCCTGCCCCAAAGAAAAGCAGTAGTGAG
CCTCCTCCACGAAAGCCCGTCGAGGAAAAGAGTGAAGAAGGGAATGTCTCGGCCCCTGGGCCTGAATCCAAACAGGCCACCACTCCAGCT
TCCAGGAAGTCAAGCAAGCAGGTCTCCCAGCCAGCACTGGTCATCCCGCCTCAGCCACCTACTACAGGACCGCCAAGAAAAGAAGTTCCC
AAAACCACTCCTAGTGAGCCCAAGAAAAAGCAGCCTCCACCACCAGAATCAGGTCCAGAGCAGAGCAAACAGAAAAAAGTGGCTCCCCGC
CCAAGTATCCCTGTAAAACAAAAACCAAAAGAAAAGGAAAAACCACCTCCGGTCAATAAGCAGGAGAATGCAGGCACTTTGAACATCCTC
AGCACTCTCTCCAATGGCAATAGTTCTAAGCAAAAAATTCCAGCAGATGGAGTCCACAGGATCAGAGTGGACTTTAAGGAGGAGCCGAGG
AAGGTCTGCTTCACCTACGACCTGTTCCTGAACCTGGAAGGCAACCCGCCCGTGAACCACCTGCGCTGCGAGAAGCTCACCTTCAACAAC
CCCACCACGGAGTTCCGGTACAAGCTCCTGCGGGCCGGCGGGGTGATGGTAATGCCCGAAGGAGCAGACACGGTGTCCAGGCCCAGTCCC
GACTACCCCATGTTACCCACAATTCCACTCTCTGCCTTCTCTGACCCCAAGAAGACCAAACCATCCCACGGCTCCAAGGACGCCAACAAG
GAGAGCAGCAAGACCTCCAAGCCACACAAGGTGACCAAGGAGCACCGGGAGCGGCCCCGCAAAGACTCCGAGAGCAAGAGCTCCTCCAAG
GAGCTGGAGCGTGAGCAGGCCAAAAGCTCCAAGGACACCTCGCGGAAGCTGGGCGAGGGCCGGCTGCCCAAGGAGGAGAAGGCGCCACCG
CCCAAGGCTGCCTTCAAGGAACCCAAGATGGCCCTGAAAGAGACCAAGCTGGAAAGCACGTCCCCCAAGGGTGGGCCCCCACCCCCACCC
CCACCCCCACCCCGGGCTTCCAGCAAGCGGCCGGCCACCGCCGACTCGCCAAAGCCCAGCGCCAAGAAGCAGAAGAAGAGCAGCTCGAAG
GGGTCCCGGAGTGCTCCAGGCACCTCGCCCCGCACCTCCTCCTCCTCCTCCTTCTCGGACAAGAAGCCGGCCAAGGACAAGAGCAGCACC
AGAGGGGAGAAGGTGAAGGCCGAGAGTGAGCCCCGGGAGGCCAAAAAGGCCCTGGAGGTGGAGGAGTCCAACTCAGAGGACGAGGCCTCC
TTCAAGTCCGAGTCTGCCCAGTCAAGCCCGTCCAACTCCAGCTCCAGCTCAGACTCCAGCTCAGACTCAGACTTCGAGCCATCCCAGAAC
CACAGCCAAGGACCCCTGCGCTCCATGGTGGAGGACCTGCAGTCCGAGGAGTCCGACGAGGACGACTCTTCGTCAGGCGAGGAGGCTGCC
GGCAAGACCAACCCGGGGAGGGACTCCAGGTTGAGCTTCAGCGACAGCGAGAGTGACAACAGCGCCGACTCCTCCCTGCCCAGCCGTGAG
CCCCCACCCCCCCAGAAGCCACCCCCGCCCAACAGCAAGGTGTCAGGCCGGAGGAGCCCCGAGTCCTGCAGCAAGCCTGAGAAGATCCTC
AAGAAGGGCACCTACGACAAGGCCTACACGGATGAGCTGGTGGAGCTACACCGGAGGCTGATGGCGCTGCGGGAGCGCAACGTGCTGCAG
CAGATTGTGAATCTGATCGAGGAGACTGGCCACTTCAATGTCACCAACACCACCTTCGACTTCGACCTCTTCTCCCTGGACGAGACCACC
GTGCGCAAACTGCAGAGCTGCCTGGAGGCCGTGGCCACATGACCCTGGGCCGCGTGCCGGGCCCCCACCGCCGGGGTCCTGGGAGGCTGC

>In-frame_ENST00000389506_ENST00000252674_AY040555_KMT2A_chr11_118355030_+_MLLT1_chr19_6230726_length(amino acids)=1873AA_start in transcript=0_stop in transcript=5621
MAHSCRWRFPARPGTTGGGGGGGRRGLGGAPRQRVPALLLPPGPPVGGGGPGAPPSPPAVAAAAAAAGSSGAGVPGGAAAASAASSSSAS
SSSSSSSSASSGPALLRVGPGFDAALQVSAAIGTNLRRFRAVFGESGGGGGSGEDEQFLGFGSDEEVRVRSPTRSPSVKTSPRKPRGRPR
SGSDRNSAILSDPSVFSPLNKSETKSGDKIKKKDSKSIEKKRGRPPTFPGVKIKITHGKDISELPKGNKEDSLKKIKRTPSATFQQATKI
KKLRAGKLSPLKSKFKTGKLQIGRKGVQIVRRRGRPPSTERIKTPSGLLINSELEKPQKVRKDKEGTPPLTKEDKTVVRQSPRRIKPVRI
IPSSKRTDATIAKQLLQRAKKGAQKKIEKEAAQLQGRKVKTQVKNIRQFIMPVVSAISSRIIKTPRRFIEDEDYDPPIKIARLESTPNSR
FSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGS
RTTKKLSTLQSAPQQQTSSSPPPPLLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQ
YFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSN
RTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESA
EKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQ
SSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKILIKKGRGNLEKTNLDLGPTAPSLEKEKTLC
LSTPSSSTVKHSTSSIGSMLAQADKLPMTDKRVASLLKKAKAQLCKIEKSKSLKQTDQPKAQGQESDSSETSVRGPRIKHVCRRAAVALG
RKRAVFPDDMPTLSALPWEEREKILSSMGNDDKSSIAGSEDAEPLAPPIKPIKPVTRNKAPQEPPVKKGRRSRRCGQCPGCQVPEDCGVC
TNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKSSSE
PPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPR
PSIPVKQKPKEKEKPPPVNKQENAGTLNILSTLSNGNSSKQKIPADGVHRIRVDFKEEPRKVCFTYDLFLNLEGNPPVNHLRCEKLTFNN
PTTEFRYKLLRAGGVMVMPEGADTVSRPSPDYPMLPTIPLSAFSDPKKTKPSHGSKDANKESSKTSKPHKVTKEHRERPRKDSESKSSSK
ELEREQAKSSKDTSRKLGEGRLPKEEKAPPPKAAFKEPKMALKETKLESTSPKGGPPPPPPPPPRASSKRPATADSPKPSAKKQKKSSSK
GSRSAPGTSPRTSSSSSFSDKKPAKDKSSTRGEKVKAESEPREAKKALEVEESNSEDEASFKSESAQSSPSNSSSSSDSSSDSDFEPSQN
HSQGPLRSMVEDLQSEESDEDDSSSGEEAAGKTNPGRDSRLSFSDSESDNSADSSLPSREPPPPQKPPPPNSKVSGRRSPESCSKPEKIL

--------------------------------------------------------------
>In-frame_ENST00000354520_ENST00000252674_AY040555_KMT2A_chr11_118355030_+_MLLT1_chr19_6230726_length(transcript)=5709nt_BP=4218nt
ATGGCGCACAGCTGTCGGTGGCGCTTCCCCGCCCGACCCGGGACCACCGGGGGCGGCGGCGGCGGGGGGCGCCGGGGCCTAGGGGGCGCC
CCGCGGCAACGCGTCCCGGCCCTGCTGCTTCCCCCCGGGCCCCCGGTCGGCGGTGGCGGCCCCGGGGCGCCCCCCTCCCCCCCGGCTGTG
GCGGCCGCGGCGGCGGCGGCGGGAAGCAGCGGGGCTGGGGTTCCAGGGGGAGCGGCCGCCGCCTCAGCAGCCTCCTCGTCGTCCGCCTCG
TCTTCGTCTTCGTCATCGTCCTCAGCCTCTTCAGGGCCGGCCCTGCTCCGGGTGGGCCCGGGCTTCGACGCGGCGCTGCAGGTCTCGGCC
GCCATCGGCACCAACCTGCGCCGGTTCCGGGCCGTGTTTGGGGAGAGCGGCGGGGGAGGCGGCAGCGGAGAGGATGAGCAATTCTTAGGT
TTTGGCTCAGATGAAGAAGTCAGAGTGCGAAGTCCCACAAGGTCTCCTTCAGTTAAAACTAGTCCTCGAAAACCTCGTGGGAGACCTAGA
AGTGGCTCTGACCGAAATTCAGCTATCCTCTCAGATCCATCTGTGTTTTCCCCTCTAAATAAATCAGAGACCAAATCTGGAGATAAGATC
AAGAAGAAAGATTCTAAAAGTATAGAAAAGAAGAGAGGAAGACCTCCCACCTTCCCTGGAGTAAAAATCAAAATAACACATGGAAAGGAC
ATTTCAGAGTTACCAAAGGGAAACAAAGAAGATAGCCTGAAAAAAATTAAAAGGACACCTTCTGCTACGTTTCAGCAAGCCACAAAGATT
AAAAAATTAAGAGCAGGTAAACTCTCTCCTCTCAAGTCTAAGTTTAAGACAGGGAAGCTTCAAATAGGAAGGAAGGGGGTACAAATTGTA
CGACGGAGAGGAAGGCCTCCATCAACAGAAAGGATAAAGACCCCTTCGGGTCTCCTCATTAATTCTGAACTGGAAAAGCCCCAGAAAGTC
CGGAAAGACAAGGAAGGAACACCTCCACTTACAAAAGAAGATAAGACAGTTGTCAGACAAAGCCCTCGAAGGATTAAGCCAGTTAGGATT
ATTCCTTCTTCAAAAAGGACAGATGCAACCATTGCTAAGCAACTCTTACAGAGGGCAAAAAAGGGGGCTCAAAAGAAAATTGAAAAAGAA
GCAGCTCAGCTGCAGGGAAGAAAGGTGAAGACACAGGTCAAAAATATTCGACAGTTCATCATGCCTGTTGTCAGTGCTATCTCCTCGCGG
ATCATTAAGACCCCTCGGCGGTTTATAGAGGATGAGGATTATGACCCTCCAATTAAAATTGCCCGATTAGAGTCTACACCGAATAGTAGA
TTCAGTGCCCCGTCCTGTGGATCTTCTGAAAAATCAAGTGCAGCTTCTCAGCACTCCTCTCAAATGTCTTCAGACTCCTCTCGATCTAGT
AGCCCCAGTGTTGATACCTCCACAGACTCTCAGGCTTCTGAGGAGATTCAGGTACTTCCTGAGGAGCGGAGCGATACCCCTGAAGTTCAT
CCTCCACTGCCCATTTCCCAGTCCCCAGAAAATGAGAGTAATGATAGGAGAAGCAGAAGGTATTCAGTGTCGGAGAGAAGTTTTGGATCT
AGAACGACGAAAAAATTATCAACTCTACAAAGTGCCCCCCAGCAGCAGACCTCCTCGTCTCCACCTCCACCTCTGCTGACTCCACCGCCA
CCACTGCAGCCAGCCTCCAGTATCTCTGACCACACACCTTGGCTTATGCCTCCAACAATCCCCTTAGCATCACCATTTTTGCCTGCTTCC
ACTGCTCCTATGCAAGGGAAGCGAAAATCTATTTTGCGAGAACCGACATTTAGGTGGACTTCTTTAAAGCATTCTAGGTCAGAGCCACAA
TACTTTTCCTCAGCAAAGTATGCCAAAGAAGGTCTTATTCGCAAACCAATATTTGATAATTTCCGACCCCCTCCACTAACTCCCGAGGAC
GTTGGCTTTGCATCTGGTTTTTCTGCATCTGGTACCGCTGCTTCAGCCCGATTGTTTTCGCCACTCCATTCTGGAACAAGGTTTGATATG
CACAAAAGGAGCCCTCTTCTGAGAGCTCCAAGATTTACTCCAAGTGAGGCTCACTCTAGAATATTTGAGTCTGTAACCTTGCCTAGTAAT
CGAACTTCTGCTGGAACATCTTCTTCAGGAGTATCCAATAGAAAAAGGAAAAGAAAAGTGTTTAGTCCTATTCGATCTGAACCAAGATCT
CCTTCTCACTCCATGAGGACAAGAAGTGGAAGGCTTAGTAGTTCTGAGCTCTCACCTCTCACCCCCCCGTCTTCTGTCTCTTCCTCGTTA
AGCATTTCTGTTAGTCCTCTTGCCACTAGTGCCTTAAACCCAACTTTTACTTTTCCTTCTCATTCCCTGACTCAGTCTGGGGAATCTGCA
GAGAAAAATCAGAGACCAAGGAAGCAGACTAGTGCTCCGGCAGAGCCATTTTCATCAAGTAGTCCTACTCCTCTCTTCCCTTGGTTTACC
CCAGGCTCTCAGACTGAAAGAGGGAGAAATAAAGACAAGGCCCCCGAGGAGCTGTCCAAAGATCGAGATGCTGACAAGAGCGTGGAGAAG
GACAAGAGTAGAGAGAGAGACCGGGAGAGAGAAAAGGAGAATAAGCGGGAGTCAAGGAAAGAGAAAAGGAAAAAGGGATCAGAAATTCAG
AGTAGTTCTGCTTTGTATCCTGTGGGTAGGGTTTCCAAAGAGAAGGTTGTTGGTGAAGATGTTGCCACTTCATCTTCTGCCAAAAAAGCA
ACAGGGCGGAAGAAGTCTTCATCACATGATTCTGGGACTGATATTACTTCTGTGACTCTTGGGGATACAACAGCTGTCAAAACCAAAATA
CTTATAAAGAAAGGGAGAGGAAATCTGGAAAAAACCAACTTGGACCTCGGCCCAACTGCCCCATCCCTGGAGAAGGAGAAAACCCTCTGC
CTTTCCACTCCTTCATCTAGCACTGTTAAACATTCCACTTCCTCCATAGGCTCCATGTTGGCTCAGGCAGACAAGCTTCCAATGACTGAC
AAGAGGGTTGCCAGCCTCCTAAAAAAGGCCAAAGCTCAGCTCTGCAAGATTGAGAAGAGTAAGAGTCTTAAACAAACCGACCAGCCCAAA
GCACAGGGTCAAGAAAGTGACTCATCAGAGACCTCTGTGCGAGGACCCCGGATTAAACATGTCTGCAGAAGAGCAGCTGTTGCCCTTGGC
CGAAAACGAGCTGTGTTTCCTGATGACATGCCCACCCTGAGTGCCTTACCATGGGAAGAACGAGAAAAGATTTTGTCTTCCATGGGGAAT
GATGACAAGTCATCAATTGCTGGCTCAGAAGATGCTGAACCTCTTGCTCCACCCATCAAACCAATTAAACCTGTCACTAGAAACAAGGCA
CCCCAGGAACCTCCAGTAAAGAAAGGACGTCGATCGAGGCGGTGTGGGCAGTGTCCCGGCTGCCAGGTGCCTGAGGACTGTGGTGTTTGT
ACTAATTGCTTAGATAAGCCCAAGTTTGGTGGTCGCAATATAAAGAAGCAGTGCTGCAAGATGAGAAAATGTCAGAATCTACAATGGATG
CCTTCCAAAGCCTACCTGCAGAAGCAAGCTAAAGCTGTGAAAAAGAAAGAGAAAAAGTCTAAGACCAGTGAAAAGAAAGACAGCAAAGAG
AGCAGTGTTGTGAAGAACGTGGTGGACTCTAGTCAGAAACCTACCCCATCAGCAAGAGAGGATCCTGCCCCAAAGAAAAGCAGTAGTGAG
CCTCCTCCACGAAAGCCCGTCGAGGAAAAGAGTGAAGAAGGGAATGTCTCGGCCCCTGGGCCTGAATCCAAACAGGCCACCACTCCAGCT
TCCAGGAAGTCAAGCAAGCAGGTCTCCCAGCCAGCACTGGTCATCCCGCCTCAGCCACCTACTACAGGACCGCCAAGAAAAGAAGTTCCC
AAAACCACTCCTAGTGAGCCCAAGAAAAAGCAGCCTCCACCACCAGAATCAGGTCCAGAGCAGAGCAAACAGAAAAAAGTGGCTCCCCGC
CCAAGTATCCCTGTAAAACAAAAACCAAAAGAAAAGGAAAAACCACCTCCGGTCAATAAGCAGGAGAATGCAGGCACTTTGAACATCCTC
AGCACTCTCTCCAATGGCAATAGTTCTAAGCAAAAAATTCCAGCAGATGGAGTCCACAGGATCAGAGTGGACTTTAAGGAGGAGCCGAGG
AAGGTCTGCTTCACCTACGACCTGTTCCTGAACCTGGAAGGCAACCCGCCCGTGAACCACCTGCGCTGCGAGAAGCTCACCTTCAACAAC
CCCACCACGGAGTTCCGGTACAAGCTCCTGCGGGCCGGCGGGGTGATGGTAATGCCCGAAGGAGCAGACACGGTGTCCAGGCCCAGTCCC
GACTACCCCATGTTACCCACAATTCCACTCTCTGCCTTCTCTGACCCCAAGAAGACCAAACCATCCCACGGCTCCAAGGACGCCAACAAG
GAGAGCAGCAAGACCTCCAAGCCACACAAGGTGACCAAGGAGCACCGGGAGCGGCCCCGCAAAGACTCCGAGAGCAAGAGCTCCTCCAAG
GAGCTGGAGCGTGAGCAGGCCAAAAGCTCCAAGGACACCTCGCGGAAGCTGGGCGAGGGCCGGCTGCCCAAGGAGGAGAAGGCGCCACCG
CCCAAGGCTGCCTTCAAGGAACCCAAGATGGCCCTGAAAGAGACCAAGCTGGAAAGCACGTCCCCCAAGGGTGGGCCCCCACCCCCACCC
CCACCCCCACCCCGGGCTTCCAGCAAGCGGCCGGCCACCGCCGACTCGCCAAAGCCCAGCGCCAAGAAGCAGAAGAAGAGCAGCTCGAAG
GGGTCCCGGAGTGCTCCAGGCACCTCGCCCCGCACCTCCTCCTCCTCCTCCTTCTCGGACAAGAAGCCGGCCAAGGACAAGAGCAGCACC
AGAGGGGAGAAGGTGAAGGCCGAGAGTGAGCCCCGGGAGGCCAAAAAGGCCCTGGAGGTGGAGGAGTCCAACTCAGAGGACGAGGCCTCC
TTCAAGTCCGAGTCTGCCCAGTCAAGCCCGTCCAACTCCAGCTCCAGCTCAGACTCCAGCTCAGACTCAGACTTCGAGCCATCCCAGAAC
CACAGCCAAGGACCCCTGCGCTCCATGGTGGAGGACCTGCAGTCCGAGGAGTCCGACGAGGACGACTCTTCGTCAGGCGAGGAGGCTGCC
GGCAAGACCAACCCGGGGAGGGACTCCAGGTTGAGCTTCAGCGACAGCGAGAGTGACAACAGCGCCGACTCCTCCCTGCCCAGCCGTGAG
CCCCCACCCCCCCAGAAGCCACCCCCGCCCAACAGCAAGGTGTCAGGCCGGAGGAGCCCCGAGTCCTGCAGCAAGCCTGAGAAGATCCTC
AAGAAGGGCACCTACGACAAGGCCTACACGGATGAGCTGGTGGAGCTACACCGGAGGCTGATGGCGCTGCGGGAGCGCAACGTGCTGCAG
CAGATTGTGAATCTGATCGAGGAGACTGGCCACTTCAATGTCACCAACACCACCTTCGACTTCGACCTCTTCTCCCTGGACGAGACCACC
GTGCGCAAACTGCAGAGCTGCCTGGAGGCCGTGGCCACATGACCCTGGGCCGCGTGCCGGGCCCCCACCGCCGGGGTCCTGGGAGGCTGC

>In-frame_ENST00000354520_ENST00000252674_AY040555_KMT2A_chr11_118355030_+_MLLT1_chr19_6230726_length(amino acids)=1873AA_start in transcript=0_stop in transcript=5621
MAHSCRWRFPARPGTTGGGGGGGRRGLGGAPRQRVPALLLPPGPPVGGGGPGAPPSPPAVAAAAAAAGSSGAGVPGGAAAASAASSSSAS
SSSSSSSSASSGPALLRVGPGFDAALQVSAAIGTNLRRFRAVFGESGGGGGSGEDEQFLGFGSDEEVRVRSPTRSPSVKTSPRKPRGRPR
SGSDRNSAILSDPSVFSPLNKSETKSGDKIKKKDSKSIEKKRGRPPTFPGVKIKITHGKDISELPKGNKEDSLKKIKRTPSATFQQATKI
KKLRAGKLSPLKSKFKTGKLQIGRKGVQIVRRRGRPPSTERIKTPSGLLINSELEKPQKVRKDKEGTPPLTKEDKTVVRQSPRRIKPVRI
IPSSKRTDATIAKQLLQRAKKGAQKKIEKEAAQLQGRKVKTQVKNIRQFIMPVVSAISSRIIKTPRRFIEDEDYDPPIKIARLESTPNSR
FSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGS
RTTKKLSTLQSAPQQQTSSSPPPPLLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQ
YFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSN
RTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESA
EKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQ
SSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKILIKKGRGNLEKTNLDLGPTAPSLEKEKTLC
LSTPSSSTVKHSTSSIGSMLAQADKLPMTDKRVASLLKKAKAQLCKIEKSKSLKQTDQPKAQGQESDSSETSVRGPRIKHVCRRAAVALG
RKRAVFPDDMPTLSALPWEEREKILSSMGNDDKSSIAGSEDAEPLAPPIKPIKPVTRNKAPQEPPVKKGRRSRRCGQCPGCQVPEDCGVC
TNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKSSSE
PPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPR
PSIPVKQKPKEKEKPPPVNKQENAGTLNILSTLSNGNSSKQKIPADGVHRIRVDFKEEPRKVCFTYDLFLNLEGNPPVNHLRCEKLTFNN
PTTEFRYKLLRAGGVMVMPEGADTVSRPSPDYPMLPTIPLSAFSDPKKTKPSHGSKDANKESSKTSKPHKVTKEHRERPRKDSESKSSSK
ELEREQAKSSKDTSRKLGEGRLPKEEKAPPPKAAFKEPKMALKETKLESTSPKGGPPPPPPPPPRASSKRPATADSPKPSAKKQKKSSSK
GSRSAPGTSPRTSSSSSFSDKKPAKDKSSTRGEKVKAESEPREAKKALEVEESNSEDEASFKSESAQSSPSNSSSSSDSSSDSDFEPSQN
HSQGPLRSMVEDLQSEESDEDDSSSGEEAAGKTNPGRDSRLSFSDSESDNSADSSLPSREPPPPQKPPPPNSKVSGRRSPESCSKPEKIL

--------------------------------------------------------------
>In-frame_ENST00000534358_ENST00000252674_AY187921_KMT2A_chr11_118355690_+_MLLT1_chr19_6270772_length(transcript)=6110nt_BP=4355nt
CTGCTTCACTTCACGGGGCGAACATGGCGCACAGCTGTCGGTGGCGCTTCCCCGCCCGACCCGGGACCACCGGGGGCGGCGGCGGCGGGG
GGCGCCGGGGCCTAGGGGGCGCCCCGCGGCAACGCGTCCCGGCCCTGCTGCTTCCCCCCGGGCCCCCGGTCGGCGGTGGCGGCCCCGGGG
CGCCCCCCTCCCCCCCGGCTGTGGCGGCCGCGGCGGCGGCGGCGGGAAGCAGCGGGGCTGGGGTTCCAGGGGGAGCGGCCGCCGCCTCAG
CAGCCTCCTCGTCGTCCGCCTCGTCTTCGTCTTCGTCATCGTCCTCAGCCTCTTCAGGGCCGGCCCTGCTCCGGGTGGGCCCGGGCTTCG
ACGCGGCGCTGCAGGTCTCGGCCGCCATCGGCACCAACCTGCGCCGGTTCCGGGCCGTGTTTGGGGAGAGCGGCGGGGGAGGCGGCAGCG
GAGAGGATGAGCAATTCTTAGGTTTTGGCTCAGATGAAGAAGTCAGAGTGCGAAGTCCCACAAGGTCTCCTTCAGTTAAAACTAGTCCTC
GAAAACCTCGTGGGAGACCTAGAAGTGGCTCTGACCGAAATTCAGCTATCCTCTCAGATCCATCTGTGTTTTCCCCTCTAAATAAATCAG
AGACCAAATCTGGAGATAAGATCAAGAAGAAAGATTCTAAAAGTATAGAAAAGAAGAGAGGAAGACCTCCCACCTTCCCTGGAGTAAAAA
TCAAAATAACACATGGAAAGGACATTTCAGAGTTACCAAAGGGAAACAAAGAAGATAGCCTGAAAAAAATTAAAAGGACACCTTCTGCTA
CGTTTCAGCAAGCCACAAAGATTAAAAAATTAAGAGCAGGTAAACTCTCTCCTCTCAAGTCTAAGTTTAAGACAGGGAAGCTTCAAATAG
GAAGGAAGGGGGTACAAATTGTACGACGGAGAGGAAGGCCTCCATCAACAGAAAGGATAAAGACCCCTTCGGGTCTCCTCATTAATTCTG
AACTGGAAAAGCCCCAGAAAGTCCGGAAAGACAAGGAAGGAACACCTCCACTTACAAAAGAAGATAAGACAGTTGTCAGACAAAGCCCTC
GAAGGATTAAGCCAGTTAGGATTATTCCTTCTTCAAAAAGGACAGATGCAACCATTGCTAAGCAACTCTTACAGAGGGCAAAAAAGGGGG
CTCAAAAGAAAATTGAAAAAGAAGCAGCTCAGCTGCAGGGAAGAAAGGTGAAGACACAGGTCAAAAATATTCGACAGTTCATCATGCCTG
TTGTCAGTGCTATCTCCTCGCGGATCATTAAGACCCCTCGGCGGTTTATAGAGGATGAGGATTATGACCCTCCAATTAAAATTGCCCGAT
TAGAGTCTACACCGAATAGTAGATTCAGTGCCCCGTCCTGTGGATCTTCTGAAAAATCAAGTGCAGCTTCTCAGCACTCCTCTCAAATGT
CTTCAGACTCCTCTCGATCTAGTAGCCCCAGTGTTGATACCTCCACAGACTCTCAGGCTTCTGAGGAGATTCAGGTACTTCCTGAGGAGC
GGAGCGATACCCCTGAAGTTCATCCTCCACTGCCCATTTCCCAGTCCCCAGAAAATGAGAGTAATGATAGGAGAAGCAGAAGGTATTCAG
TGTCGGAGAGAAGTTTTGGATCTAGAACGACGAAAAAATTATCAACTCTACAAAGTGCCCCCCAGCAGCAGACCTCCTCGTCTCCACCTC
CACCTCTGCTGACTCCACCGCCACCACTGCAGCCAGCCTCCAGTATCTCTGACCACACACCTTGGCTTATGCCTCCAACAATCCCCTTAG
CATCACCATTTTTGCCTGCTTCCACTGCTCCTATGCAAGGGAAGCGAAAATCTATTTTGCGAGAACCGACATTTAGGTGGACTTCTTTAA
AGCATTCTAGGTCAGAGCCACAATACTTTTCCTCAGCAAAGTATGCCAAAGAAGGTCTTATTCGCAAACCAATATTTGATAATTTCCGAC
CCCCTCCACTAACTCCCGAGGACGTTGGCTTTGCATCTGGTTTTTCTGCATCTGGTACCGCTGCTTCAGCCCGATTGTTTTCGCCACTCC
ATTCTGGAACAAGGTTTGATATGCACAAAAGGAGCCCTCTTCTGAGAGCTCCAAGATTTACTCCAAGTGAGGCTCACTCTAGAATATTTG
AGTCTGTAACCTTGCCTAGTAATCGAACTTCTGCTGGAACATCTTCTTCAGGAGTATCCAATAGAAAAAGGAAAAGAAAAGTGTTTAGTC
CTATTCGATCTGAACCAAGATCTCCTTCTCACTCCATGAGGACAAGAAGTGGAAGGCTTAGTAGTTCTGAGCTCTCACCTCTCACCCCCC
CGTCTTCTGTCTCTTCCTCGTTAAGCATTTCTGTTAGTCCTCTTGCCACTAGTGCCTTAAACCCAACTTTTACTTTTCCTTCTCATTCCC
TGACTCAGTCTGGGGAATCTGCAGAGAAAAATCAGAGACCAAGGAAGCAGACTAGTGCTCCGGCAGAGCCATTTTCATCAAGTAGTCCTA
CTCCTCTCTTCCCTTGGTTTACCCCAGGCTCTCAGACTGAAAGAGGGAGAAATAAAGACAAGGCCCCCGAGGAGCTGTCCAAAGATCGAG
ATGCTGACAAGAGCGTGGAGAAGGACAAGAGTAGAGAGAGAGACCGGGAGAGAGAAAAGGAGAATAAGCGGGAGTCAAGGAAAGAGAAAA
GGAAAAAGGGATCAGAAATTCAGAGTAGTTCTGCTTTGTATCCTGTGGGTAGGGTTTCCAAAGAGAAGGTTGTTGGTGAAGATGTTGCCA
CTTCATCTTCTGCCAAAAAAGCAACAGGGCGGAAGAAGTCTTCATCACATGATTCTGGGACTGATATTACTTCTGTGACTCTTGGGGATA
CAACAGCTGTCAAAACCAAAATACTTATAAAGAAAGGGAGAGGAAATCTGGAAAAAACCAACTTGGACCTCGGCCCAACTGCCCCATCCC
TGGAGAAGGAGAAAACCCTCTGCCTTTCCACTCCTTCATCTAGCACTGTTAAACATTCCACTTCCTCCATAGGCTCCATGTTGGCTCAGG
CAGACAAGCTTCCAATGACTGACAAGAGGGTTGCCAGCCTCCTAAAAAAGGCCAAAGCTCAGCTCTGCAAGATTGAGAAGAGTAAGAGTC
TTAAACAAACCGACCAGCCCAAAGCACAGGGTCAAGAAAGTGACTCATCAGAGACCTCTGTGCGAGGACCCCGGATTAAACATGTCTGCA
GAAGAGCAGCTGTTGCCCTTGGCCGAAAACGAGCTGTGTTTCCTGATGACATGCCCACCCTGAGTGCCTTACCATGGGAAGAACGAGAAA
AGATTTTGTCTTCCATGGGGAATGATGACAAGTCATCAATTGCTGGCTCAGAAGATGCTGAACCTCTTGCTCCACCCATCAAACCAATTA
AACCTGTCACTAGAAACAAGGCACCCCAGGAACCTCCAGTAAAGAAAGGACGTCGATCGAGGCGGTGTGGGCAGTGTCCCGGCTGCCAGG
TGCCTGAGGACTGTGGTGTTTGTACTAATTGCTTAGATAAGCCCAAGTTTGGTGGTCGCAATATAAAGAAGCAGTGCTGCAAGATGAGAA
AATGTCAGAATCTACAATGGATGCCTTCCAAAGCCTACCTGCAGAAGCAAGCTAAAGCTGTGAAAAAGAAAGAGAAAAAGTCTAAGACCA
GTGAAAAGAAAGACAGCAAAGAGAGCAGTGTTGTGAAGAACGTGGTGGACTCTAGTCAGAAACCTACCCCATCAGCAAGAGAGGATCCTG
CCCCAAAGAAAAGCAGTAGTGAGCCTCCTCCACGAAAGCCCGTCGAGGAAAAGAGTGAAGAAGGGAATGTCTCGGCCCCTGGGCCTGAAT
CCAAACAGGCCACCACTCCAGCTTCCAGGAAGTCAAGCAAGCAGGTCTCCCAGCCAGCACTGGTCATCCCGCCTCAGCCACCTACTACAG
GACCGCCAAGAAAAGAAGTTCCCAAAACCACTCCTAGTGAGCCCAAGAAAAAGCAGCCTCCACCACCAGAATCAGGTCCAGAGCAGAGCA
AACAGAAAAAAGTGGCTCCCCGCCCAAGTATCCCTGTAAAACAAAAACCAAAAGAAAAGGAAAAACCACCTCCGGTCAATAAGCAGGAGA
ATGCAGGCACTTTGAACATCCTCAGCACTCTCTCCAATGGCAATAGTTCTAAGCAAAAAATTCCAGCAGATGGAGTCCACAGGATCAGAG
TGGACTTTAAGGAGGATTGTGAAGCAGAAAATGTGTGGGAGATGGGAGGCTTAGGAATCTTGACTTCTGTTCCTATAACACCCAGGGTGG
TTTGCTTTCTCTGTGCCAGTAGTGGGCATGTAGAGTGCACCGTCCAGGTGAGGTTAGAGCTGGGGCATCGCGCCCAACTGCGCAAGAAGC
CCACCACGGAGGGGTTCACTCACGACTGGATGGTGTTTGTCCGCGGCCCCGAGCAATGTGACATCCAGCACTTCGTGGAGAAGGTGGTCT
TCTGGCTGCACGACAGCTTCCCCAAGCCCAGACGCGTGTGCAAGGAGCCCCCCTACAAAGTAGAGGAGTCGGGGTACGCTGGCTTCATCA
TGCCCATCGAGGTGCACTTCAAAAACAAGGAGGAGCCGAGGAAGGTCTGCTTCACCTACGACCTGTTCCTGAACCTGGAAGGCAACCCGC
CCGTGAACCACCTGCGCTGCGAGAAGCTCACCTTCAACAACCCCACCACGGAGTTCCGGTACAAGCTCCTGCGGGCCGGCGGGGTGATGG
TAATGCCCGAAGGAGCAGACACGGTGTCCAGGCCCAGTCCCGACTACCCCATGTTACCCACAATTCCACTCTCTGCCTTCTCTGACCCCA
AGAAGACCAAACCATCCCACGGCTCCAAGGACGCCAACAAGGAGAGCAGCAAGACCTCCAAGCCACACAAGGTGACCAAGGAGCACCGGG
AGCGGCCCCGCAAAGACTCCGAGAGCAAGAGCTCCTCCAAGGAGCTGGAGCGTGAGCAGGCCAAAAGCTCCAAGGACACCTCGCGGAAGC
TGGGCGAGGGCCGGCTGCCCAAGGAGGAGAAGGCGCCACCGCCCAAGGCTGCCTTCAAGGAACCCAAGATGGCCCTGAAAGAGACCAAGC
TGGAAAGCACGTCCCCCAAGGGTGGGCCCCCACCCCCACCCCCACCCCCACCCCGGGCTTCCAGCAAGCGGCCGGCCACCGCCGACTCGC
CAAAGCCCAGCGCCAAGAAGCAGAAGAAGAGCAGCTCGAAGGGGTCCCGGAGTGCTCCAGGCACCTCGCCCCGCACCTCCTCCTCCTCCT
CCTTCTCGGACAAGAAGCCGGCCAAGGACAAGAGCAGCACCAGAGGGGAGAAGGTGAAGGCCGAGAGTGAGCCCCGGGAGGCCAAAAAGG
CCCTGGAGGTGGAGGAGTCCAACTCAGAGGACGAGGCCTCCTTCAAGTCCGAGTCTGCCCAGTCAAGCCCGTCCAACTCCAGCTCCAGCT
CAGACTCCAGCTCAGACTCAGACTTCGAGCCATCCCAGAACCACAGCCAAGGACCCCTGCGCTCCATGGTGGAGGACCTGCAGTCCGAGG
AGTCCGACGAGGACGACTCTTCGTCAGGCGAGGAGGCTGCCGGCAAGACCAACCCGGGGAGGGACTCCAGGTTGAGCTTCAGCGACAGCG
AGAGTGACAACAGCGCCGACTCCTCCCTGCCCAGCCGTGAGCCCCCACCCCCCCAGAAGCCACCCCCGCCCAACAGCAAGGTGTCAGGCC
GGAGGAGCCCCGAGTCCTGCAGCAAGCCTGAGAAGATCCTCAAGAAGGGCACCTACGACAAGGCCTACACGGATGAGCTGGTGGAGCTAC
ACCGGAGGCTGATGGCGCTGCGGGAGCGCAACGTGCTGCAGCAGATTGTGAATCTGATCGAGGAGACTGGCCACTTCAATGTCACCAACA
CCACCTTCGACTTCGACCTCTTCTCCCTGGACGAGACCACCGTGCGCAAACTGCAGAGCTGCCTGGAGGCCGTGGCCACATGACCCTGGG

>In-frame_ENST00000534358_ENST00000252674_AY187921_KMT2A_chr11_118355690_+_MLLT1_chr19_6270772_length(amino acids)=1999AA_start in transcript=23_stop in transcript=6022
MAHSCRWRFPARPGTTGGGGGGGRRGLGGAPRQRVPALLLPPGPPVGGGGPGAPPSPPAVAAAAAAAGSSGAGVPGGAAAASAASSSSAS
SSSSSSSSASSGPALLRVGPGFDAALQVSAAIGTNLRRFRAVFGESGGGGGSGEDEQFLGFGSDEEVRVRSPTRSPSVKTSPRKPRGRPR
SGSDRNSAILSDPSVFSPLNKSETKSGDKIKKKDSKSIEKKRGRPPTFPGVKIKITHGKDISELPKGNKEDSLKKIKRTPSATFQQATKI
KKLRAGKLSPLKSKFKTGKLQIGRKGVQIVRRRGRPPSTERIKTPSGLLINSELEKPQKVRKDKEGTPPLTKEDKTVVRQSPRRIKPVRI
IPSSKRTDATIAKQLLQRAKKGAQKKIEKEAAQLQGRKVKTQVKNIRQFIMPVVSAISSRIIKTPRRFIEDEDYDPPIKIARLESTPNSR
FSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGS
RTTKKLSTLQSAPQQQTSSSPPPPLLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQ
YFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSN
RTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESA
EKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQ
SSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKILIKKGRGNLEKTNLDLGPTAPSLEKEKTLC
LSTPSSSTVKHSTSSIGSMLAQADKLPMTDKRVASLLKKAKAQLCKIEKSKSLKQTDQPKAQGQESDSSETSVRGPRIKHVCRRAAVALG
RKRAVFPDDMPTLSALPWEEREKILSSMGNDDKSSIAGSEDAEPLAPPIKPIKPVTRNKAPQEPPVKKGRRSRRCGQCPGCQVPEDCGVC
TNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKSSSE
PPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPR
PSIPVKQKPKEKEKPPPVNKQENAGTLNILSTLSNGNSSKQKIPADGVHRIRVDFKEDCEAENVWEMGGLGILTSVPITPRVVCFLCASS
GHVECTVQVRLELGHRAQLRKKPTTEGFTHDWMVFVRGPEQCDIQHFVEKVVFWLHDSFPKPRRVCKEPPYKVEESGYAGFIMPIEVHFK
NKEEPRKVCFTYDLFLNLEGNPPVNHLRCEKLTFNNPTTEFRYKLLRAGGVMVMPEGADTVSRPSPDYPMLPTIPLSAFSDPKKTKPSHG
SKDANKESSKTSKPHKVTKEHRERPRKDSESKSSSKELEREQAKSSKDTSRKLGEGRLPKEEKAPPPKAAFKEPKMALKETKLESTSPKG
GPPPPPPPPPRASSKRPATADSPKPSAKKQKKSSSKGSRSAPGTSPRTSSSSSFSDKKPAKDKSSTRGEKVKAESEPREAKKALEVEESN
SEDEASFKSESAQSSPSNSSSSSDSSSDSDFEPSQNHSQGPLRSMVEDLQSEESDEDDSSSGEEAAGKTNPGRDSRLSFSDSESDNSADS
SLPSREPPPPQKPPPPNSKVSGRRSPESCSKPEKILKKGTYDKAYTDELVELHRRLMALRERNVLQQIVNLIEETGHFNVTNTTFDFDLF

--------------------------------------------------------------
>In-frame_ENST00000389506_ENST00000252674_AY187921_KMT2A_chr11_118355690_+_MLLT1_chr19_6270772_length(transcript)=6087nt_BP=4332nt
ATGGCGCACAGCTGTCGGTGGCGCTTCCCCGCCCGACCCGGGACCACCGGGGGCGGCGGCGGCGGGGGGCGCCGGGGCCTAGGGGGCGCC
CCGCGGCAACGCGTCCCGGCCCTGCTGCTTCCCCCCGGGCCCCCGGTCGGCGGTGGCGGCCCCGGGGCGCCCCCCTCCCCCCCGGCTGTG
GCGGCCGCGGCGGCGGCGGCGGGAAGCAGCGGGGCTGGGGTTCCAGGGGGAGCGGCCGCCGCCTCAGCAGCCTCCTCGTCGTCCGCCTCG
TCTTCGTCTTCGTCATCGTCCTCAGCCTCTTCAGGGCCGGCCCTGCTCCGGGTGGGCCCGGGCTTCGACGCGGCGCTGCAGGTCTCGGCC
GCCATCGGCACCAACCTGCGCCGGTTCCGGGCCGTGTTTGGGGAGAGCGGCGGGGGAGGCGGCAGCGGAGAGGATGAGCAATTCTTAGGT
TTTGGCTCAGATGAAGAAGTCAGAGTGCGAAGTCCCACAAGGTCTCCTTCAGTTAAAACTAGTCCTCGAAAACCTCGTGGGAGACCTAGA
AGTGGCTCTGACCGAAATTCAGCTATCCTCTCAGATCCATCTGTGTTTTCCCCTCTAAATAAATCAGAGACCAAATCTGGAGATAAGATC
AAGAAGAAAGATTCTAAAAGTATAGAAAAGAAGAGAGGAAGACCTCCCACCTTCCCTGGAGTAAAAATCAAAATAACACATGGAAAGGAC
ATTTCAGAGTTACCAAAGGGAAACAAAGAAGATAGCCTGAAAAAAATTAAAAGGACACCTTCTGCTACGTTTCAGCAAGCCACAAAGATT
AAAAAATTAAGAGCAGGTAAACTCTCTCCTCTCAAGTCTAAGTTTAAGACAGGGAAGCTTCAAATAGGAAGGAAGGGGGTACAAATTGTA
CGACGGAGAGGAAGGCCTCCATCAACAGAAAGGATAAAGACCCCTTCGGGTCTCCTCATTAATTCTGAACTGGAAAAGCCCCAGAAAGTC
CGGAAAGACAAGGAAGGAACACCTCCACTTACAAAAGAAGATAAGACAGTTGTCAGACAAAGCCCTCGAAGGATTAAGCCAGTTAGGATT
ATTCCTTCTTCAAAAAGGACAGATGCAACCATTGCTAAGCAACTCTTACAGAGGGCAAAAAAGGGGGCTCAAAAGAAAATTGAAAAAGAA
GCAGCTCAGCTGCAGGGAAGAAAGGTGAAGACACAGGTCAAAAATATTCGACAGTTCATCATGCCTGTTGTCAGTGCTATCTCCTCGCGG
ATCATTAAGACCCCTCGGCGGTTTATAGAGGATGAGGATTATGACCCTCCAATTAAAATTGCCCGATTAGAGTCTACACCGAATAGTAGA
TTCAGTGCCCCGTCCTGTGGATCTTCTGAAAAATCAAGTGCAGCTTCTCAGCACTCCTCTCAAATGTCTTCAGACTCCTCTCGATCTAGT
AGCCCCAGTGTTGATACCTCCACAGACTCTCAGGCTTCTGAGGAGATTCAGGTACTTCCTGAGGAGCGGAGCGATACCCCTGAAGTTCAT
CCTCCACTGCCCATTTCCCAGTCCCCAGAAAATGAGAGTAATGATAGGAGAAGCAGAAGGTATTCAGTGTCGGAGAGAAGTTTTGGATCT
AGAACGACGAAAAAATTATCAACTCTACAAAGTGCCCCCCAGCAGCAGACCTCCTCGTCTCCACCTCCACCTCTGCTGACTCCACCGCCA
CCACTGCAGCCAGCCTCCAGTATCTCTGACCACACACCTTGGCTTATGCCTCCAACAATCCCCTTAGCATCACCATTTTTGCCTGCTTCC
ACTGCTCCTATGCAAGGGAAGCGAAAATCTATTTTGCGAGAACCGACATTTAGGTGGACTTCTTTAAAGCATTCTAGGTCAGAGCCACAA
TACTTTTCCTCAGCAAAGTATGCCAAAGAAGGTCTTATTCGCAAACCAATATTTGATAATTTCCGACCCCCTCCACTAACTCCCGAGGAC
GTTGGCTTTGCATCTGGTTTTTCTGCATCTGGTACCGCTGCTTCAGCCCGATTGTTTTCGCCACTCCATTCTGGAACAAGGTTTGATATG
CACAAAAGGAGCCCTCTTCTGAGAGCTCCAAGATTTACTCCAAGTGAGGCTCACTCTAGAATATTTGAGTCTGTAACCTTGCCTAGTAAT
CGAACTTCTGCTGGAACATCTTCTTCAGGAGTATCCAATAGAAAAAGGAAAAGAAAAGTGTTTAGTCCTATTCGATCTGAACCAAGATCT
CCTTCTCACTCCATGAGGACAAGAAGTGGAAGGCTTAGTAGTTCTGAGCTCTCACCTCTCACCCCCCCGTCTTCTGTCTCTTCCTCGTTA
AGCATTTCTGTTAGTCCTCTTGCCACTAGTGCCTTAAACCCAACTTTTACTTTTCCTTCTCATTCCCTGACTCAGTCTGGGGAATCTGCA
GAGAAAAATCAGAGACCAAGGAAGCAGACTAGTGCTCCGGCAGAGCCATTTTCATCAAGTAGTCCTACTCCTCTCTTCCCTTGGTTTACC
CCAGGCTCTCAGACTGAAAGAGGGAGAAATAAAGACAAGGCCCCCGAGGAGCTGTCCAAAGATCGAGATGCTGACAAGAGCGTGGAGAAG
GACAAGAGTAGAGAGAGAGACCGGGAGAGAGAAAAGGAGAATAAGCGGGAGTCAAGGAAAGAGAAAAGGAAAAAGGGATCAGAAATTCAG
AGTAGTTCTGCTTTGTATCCTGTGGGTAGGGTTTCCAAAGAGAAGGTTGTTGGTGAAGATGTTGCCACTTCATCTTCTGCCAAAAAAGCA
ACAGGGCGGAAGAAGTCTTCATCACATGATTCTGGGACTGATATTACTTCTGTGACTCTTGGGGATACAACAGCTGTCAAAACCAAAATA
CTTATAAAGAAAGGGAGAGGAAATCTGGAAAAAACCAACTTGGACCTCGGCCCAACTGCCCCATCCCTGGAGAAGGAGAAAACCCTCTGC
CTTTCCACTCCTTCATCTAGCACTGTTAAACATTCCACTTCCTCCATAGGCTCCATGTTGGCTCAGGCAGACAAGCTTCCAATGACTGAC
AAGAGGGTTGCCAGCCTCCTAAAAAAGGCCAAAGCTCAGCTCTGCAAGATTGAGAAGAGTAAGAGTCTTAAACAAACCGACCAGCCCAAA
GCACAGGGTCAAGAAAGTGACTCATCAGAGACCTCTGTGCGAGGACCCCGGATTAAACATGTCTGCAGAAGAGCAGCTGTTGCCCTTGGC
CGAAAACGAGCTGTGTTTCCTGATGACATGCCCACCCTGAGTGCCTTACCATGGGAAGAACGAGAAAAGATTTTGTCTTCCATGGGGAAT
GATGACAAGTCATCAATTGCTGGCTCAGAAGATGCTGAACCTCTTGCTCCACCCATCAAACCAATTAAACCTGTCACTAGAAACAAGGCA
CCCCAGGAACCTCCAGTAAAGAAAGGACGTCGATCGAGGCGGTGTGGGCAGTGTCCCGGCTGCCAGGTGCCTGAGGACTGTGGTGTTTGT
ACTAATTGCTTAGATAAGCCCAAGTTTGGTGGTCGCAATATAAAGAAGCAGTGCTGCAAGATGAGAAAATGTCAGAATCTACAATGGATG
CCTTCCAAAGCCTACCTGCAGAAGCAAGCTAAAGCTGTGAAAAAGAAAGAGAAAAAGTCTAAGACCAGTGAAAAGAAAGACAGCAAAGAG
AGCAGTGTTGTGAAGAACGTGGTGGACTCTAGTCAGAAACCTACCCCATCAGCAAGAGAGGATCCTGCCCCAAAGAAAAGCAGTAGTGAG
CCTCCTCCACGAAAGCCCGTCGAGGAAAAGAGTGAAGAAGGGAATGTCTCGGCCCCTGGGCCTGAATCCAAACAGGCCACCACTCCAGCT
TCCAGGAAGTCAAGCAAGCAGGTCTCCCAGCCAGCACTGGTCATCCCGCCTCAGCCACCTACTACAGGACCGCCAAGAAAAGAAGTTCCC
AAAACCACTCCTAGTGAGCCCAAGAAAAAGCAGCCTCCACCACCAGAATCAGGTCCAGAGCAGAGCAAACAGAAAAAAGTGGCTCCCCGC
CCAAGTATCCCTGTAAAACAAAAACCAAAAGAAAAGGAAAAACCACCTCCGGTCAATAAGCAGGAGAATGCAGGCACTTTGAACATCCTC
AGCACTCTCTCCAATGGCAATAGTTCTAAGCAAAAAATTCCAGCAGATGGAGTCCACAGGATCAGAGTGGACTTTAAGGAGGATTGTGAA
GCAGAAAATGTGTGGGAGATGGGAGGCTTAGGAATCTTGACTTCTGTTCCTATAACACCCAGGGTGGTTTGCTTTCTCTGTGCCAGTAGT
GGGCATGTAGAGTGCACCGTCCAGGTGAGGTTAGAGCTGGGGCATCGCGCCCAACTGCGCAAGAAGCCCACCACGGAGGGGTTCACTCAC
GACTGGATGGTGTTTGTCCGCGGCCCCGAGCAATGTGACATCCAGCACTTCGTGGAGAAGGTGGTCTTCTGGCTGCACGACAGCTTCCCC
AAGCCCAGACGCGTGTGCAAGGAGCCCCCCTACAAAGTAGAGGAGTCGGGGTACGCTGGCTTCATCATGCCCATCGAGGTGCACTTCAAA
AACAAGGAGGAGCCGAGGAAGGTCTGCTTCACCTACGACCTGTTCCTGAACCTGGAAGGCAACCCGCCCGTGAACCACCTGCGCTGCGAG
AAGCTCACCTTCAACAACCCCACCACGGAGTTCCGGTACAAGCTCCTGCGGGCCGGCGGGGTGATGGTAATGCCCGAAGGAGCAGACACG
GTGTCCAGGCCCAGTCCCGACTACCCCATGTTACCCACAATTCCACTCTCTGCCTTCTCTGACCCCAAGAAGACCAAACCATCCCACGGC
TCCAAGGACGCCAACAAGGAGAGCAGCAAGACCTCCAAGCCACACAAGGTGACCAAGGAGCACCGGGAGCGGCCCCGCAAAGACTCCGAG
AGCAAGAGCTCCTCCAAGGAGCTGGAGCGTGAGCAGGCCAAAAGCTCCAAGGACACCTCGCGGAAGCTGGGCGAGGGCCGGCTGCCCAAG
GAGGAGAAGGCGCCACCGCCCAAGGCTGCCTTCAAGGAACCCAAGATGGCCCTGAAAGAGACCAAGCTGGAAAGCACGTCCCCCAAGGGT
GGGCCCCCACCCCCACCCCCACCCCCACCCCGGGCTTCCAGCAAGCGGCCGGCCACCGCCGACTCGCCAAAGCCCAGCGCCAAGAAGCAG
AAGAAGAGCAGCTCGAAGGGGTCCCGGAGTGCTCCAGGCACCTCGCCCCGCACCTCCTCCTCCTCCTCCTTCTCGGACAAGAAGCCGGCC
AAGGACAAGAGCAGCACCAGAGGGGAGAAGGTGAAGGCCGAGAGTGAGCCCCGGGAGGCCAAAAAGGCCCTGGAGGTGGAGGAGTCCAAC
TCAGAGGACGAGGCCTCCTTCAAGTCCGAGTCTGCCCAGTCAAGCCCGTCCAACTCCAGCTCCAGCTCAGACTCCAGCTCAGACTCAGAC
TTCGAGCCATCCCAGAACCACAGCCAAGGACCCCTGCGCTCCATGGTGGAGGACCTGCAGTCCGAGGAGTCCGACGAGGACGACTCTTCG
TCAGGCGAGGAGGCTGCCGGCAAGACCAACCCGGGGAGGGACTCCAGGTTGAGCTTCAGCGACAGCGAGAGTGACAACAGCGCCGACTCC
TCCCTGCCCAGCCGTGAGCCCCCACCCCCCCAGAAGCCACCCCCGCCCAACAGCAAGGTGTCAGGCCGGAGGAGCCCCGAGTCCTGCAGC
AAGCCTGAGAAGATCCTCAAGAAGGGCACCTACGACAAGGCCTACACGGATGAGCTGGTGGAGCTACACCGGAGGCTGATGGCGCTGCGG
GAGCGCAACGTGCTGCAGCAGATTGTGAATCTGATCGAGGAGACTGGCCACTTCAATGTCACCAACACCACCTTCGACTTCGACCTCTTC
TCCCTGGACGAGACCACCGTGCGCAAACTGCAGAGCTGCCTGGAGGCCGTGGCCACATGACCCTGGGCCGCGTGCCGGGCCCCCACCGCC

>In-frame_ENST00000389506_ENST00000252674_AY187921_KMT2A_chr11_118355690_+_MLLT1_chr19_6270772_length(amino acids)=1999AA_start in transcript=0_stop in transcript=5999
MAHSCRWRFPARPGTTGGGGGGGRRGLGGAPRQRVPALLLPPGPPVGGGGPGAPPSPPAVAAAAAAAGSSGAGVPGGAAAASAASSSSAS
SSSSSSSSASSGPALLRVGPGFDAALQVSAAIGTNLRRFRAVFGESGGGGGSGEDEQFLGFGSDEEVRVRSPTRSPSVKTSPRKPRGRPR
SGSDRNSAILSDPSVFSPLNKSETKSGDKIKKKDSKSIEKKRGRPPTFPGVKIKITHGKDISELPKGNKEDSLKKIKRTPSATFQQATKI
KKLRAGKLSPLKSKFKTGKLQIGRKGVQIVRRRGRPPSTERIKTPSGLLINSELEKPQKVRKDKEGTPPLTKEDKTVVRQSPRRIKPVRI
IPSSKRTDATIAKQLLQRAKKGAQKKIEKEAAQLQGRKVKTQVKNIRQFIMPVVSAISSRIIKTPRRFIEDEDYDPPIKIARLESTPNSR
FSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGS
RTTKKLSTLQSAPQQQTSSSPPPPLLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQ
YFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSN
RTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESA
EKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQ
SSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKILIKKGRGNLEKTNLDLGPTAPSLEKEKTLC
LSTPSSSTVKHSTSSIGSMLAQADKLPMTDKRVASLLKKAKAQLCKIEKSKSLKQTDQPKAQGQESDSSETSVRGPRIKHVCRRAAVALG
RKRAVFPDDMPTLSALPWEEREKILSSMGNDDKSSIAGSEDAEPLAPPIKPIKPVTRNKAPQEPPVKKGRRSRRCGQCPGCQVPEDCGVC
TNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKSSSE
PPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPR
PSIPVKQKPKEKEKPPPVNKQENAGTLNILSTLSNGNSSKQKIPADGVHRIRVDFKEDCEAENVWEMGGLGILTSVPITPRVVCFLCASS
GHVECTVQVRLELGHRAQLRKKPTTEGFTHDWMVFVRGPEQCDIQHFVEKVVFWLHDSFPKPRRVCKEPPYKVEESGYAGFIMPIEVHFK
NKEEPRKVCFTYDLFLNLEGNPPVNHLRCEKLTFNNPTTEFRYKLLRAGGVMVMPEGADTVSRPSPDYPMLPTIPLSAFSDPKKTKPSHG
SKDANKESSKTSKPHKVTKEHRERPRKDSESKSSSKELEREQAKSSKDTSRKLGEGRLPKEEKAPPPKAAFKEPKMALKETKLESTSPKG
GPPPPPPPPPRASSKRPATADSPKPSAKKQKKSSSKGSRSAPGTSPRTSSSSSFSDKKPAKDKSSTRGEKVKAESEPREAKKALEVEESN
SEDEASFKSESAQSSPSNSSSSSDSSSDSDFEPSQNHSQGPLRSMVEDLQSEESDEDDSSSGEEAAGKTNPGRDSRLSFSDSESDNSADS
SLPSREPPPPQKPPPPNSKVSGRRSPESCSKPEKILKKGTYDKAYTDELVELHRRLMALRERNVLQQIVNLIEETGHFNVTNTTFDFDLF

--------------------------------------------------------------
>In-frame_ENST00000534358_ENST00000252674_DQ224341_KMT2A_chr11_118355030_+_MLLT1_chr19_6222697_length(transcript)=5462nt_BP=4241nt
CTGCTTCACTTCACGGGGCGAACATGGCGCACAGCTGTCGGTGGCGCTTCCCCGCCCGACCCGGGACCACCGGGGGCGGCGGCGGCGGGG
GGCGCCGGGGCCTAGGGGGCGCCCCGCGGCAACGCGTCCCGGCCCTGCTGCTTCCCCCCGGGCCCCCGGTCGGCGGTGGCGGCCCCGGGG
CGCCCCCCTCCCCCCCGGCTGTGGCGGCCGCGGCGGCGGCGGCGGGAAGCAGCGGGGCTGGGGTTCCAGGGGGAGCGGCCGCCGCCTCAG
CAGCCTCCTCGTCGTCCGCCTCGTCTTCGTCTTCGTCATCGTCCTCAGCCTCTTCAGGGCCGGCCCTGCTCCGGGTGGGCCCGGGCTTCG
ACGCGGCGCTGCAGGTCTCGGCCGCCATCGGCACCAACCTGCGCCGGTTCCGGGCCGTGTTTGGGGAGAGCGGCGGGGGAGGCGGCAGCG
GAGAGGATGAGCAATTCTTAGGTTTTGGCTCAGATGAAGAAGTCAGAGTGCGAAGTCCCACAAGGTCTCCTTCAGTTAAAACTAGTCCTC
GAAAACCTCGTGGGAGACCTAGAAGTGGCTCTGACCGAAATTCAGCTATCCTCTCAGATCCATCTGTGTTTTCCCCTCTAAATAAATCAG
AGACCAAATCTGGAGATAAGATCAAGAAGAAAGATTCTAAAAGTATAGAAAAGAAGAGAGGAAGACCTCCCACCTTCCCTGGAGTAAAAA
TCAAAATAACACATGGAAAGGACATTTCAGAGTTACCAAAGGGAAACAAAGAAGATAGCCTGAAAAAAATTAAAAGGACACCTTCTGCTA
CGTTTCAGCAAGCCACAAAGATTAAAAAATTAAGAGCAGGTAAACTCTCTCCTCTCAAGTCTAAGTTTAAGACAGGGAAGCTTCAAATAG
GAAGGAAGGGGGTACAAATTGTACGACGGAGAGGAAGGCCTCCATCAACAGAAAGGATAAAGACCCCTTCGGGTCTCCTCATTAATTCTG
AACTGGAAAAGCCCCAGAAAGTCCGGAAAGACAAGGAAGGAACACCTCCACTTACAAAAGAAGATAAGACAGTTGTCAGACAAAGCCCTC
GAAGGATTAAGCCAGTTAGGATTATTCCTTCTTCAAAAAGGACAGATGCAACCATTGCTAAGCAACTCTTACAGAGGGCAAAAAAGGGGG
CTCAAAAGAAAATTGAAAAAGAAGCAGCTCAGCTGCAGGGAAGAAAGGTGAAGACACAGGTCAAAAATATTCGACAGTTCATCATGCCTG
TTGTCAGTGCTATCTCCTCGCGGATCATTAAGACCCCTCGGCGGTTTATAGAGGATGAGGATTATGACCCTCCAATTAAAATTGCCCGAT
TAGAGTCTACACCGAATAGTAGATTCAGTGCCCCGTCCTGTGGATCTTCTGAAAAATCAAGTGCAGCTTCTCAGCACTCCTCTCAAATGT
CTTCAGACTCCTCTCGATCTAGTAGCCCCAGTGTTGATACCTCCACAGACTCTCAGGCTTCTGAGGAGATTCAGGTACTTCCTGAGGAGC
GGAGCGATACCCCTGAAGTTCATCCTCCACTGCCCATTTCCCAGTCCCCAGAAAATGAGAGTAATGATAGGAGAAGCAGAAGGTATTCAG
TGTCGGAGAGAAGTTTTGGATCTAGAACGACGAAAAAATTATCAACTCTACAAAGTGCCCCCCAGCAGCAGACCTCCTCGTCTCCACCTC
CACCTCTGCTGACTCCACCGCCACCACTGCAGCCAGCCTCCAGTATCTCTGACCACACACCTTGGCTTATGCCTCCAACAATCCCCTTAG
CATCACCATTTTTGCCTGCTTCCACTGCTCCTATGCAAGGGAAGCGAAAATCTATTTTGCGAGAACCGACATTTAGGTGGACTTCTTTAA
AGCATTCTAGGTCAGAGCCACAATACTTTTCCTCAGCAAAGTATGCCAAAGAAGGTCTTATTCGCAAACCAATATTTGATAATTTCCGAC
CCCCTCCACTAACTCCCGAGGACGTTGGCTTTGCATCTGGTTTTTCTGCATCTGGTACCGCTGCTTCAGCCCGATTGTTTTCGCCACTCC
ATTCTGGAACAAGGTTTGATATGCACAAAAGGAGCCCTCTTCTGAGAGCTCCAAGATTTACTCCAAGTGAGGCTCACTCTAGAATATTTG
AGTCTGTAACCTTGCCTAGTAATCGAACTTCTGCTGGAACATCTTCTTCAGGAGTATCCAATAGAAAAAGGAAAAGAAAAGTGTTTAGTC
CTATTCGATCTGAACCAAGATCTCCTTCTCACTCCATGAGGACAAGAAGTGGAAGGCTTAGTAGTTCTGAGCTCTCACCTCTCACCCCCC
CGTCTTCTGTCTCTTCCTCGTTAAGCATTTCTGTTAGTCCTCTTGCCACTAGTGCCTTAAACCCAACTTTTACTTTTCCTTCTCATTCCC
TGACTCAGTCTGGGGAATCTGCAGAGAAAAATCAGAGACCAAGGAAGCAGACTAGTGCTCCGGCAGAGCCATTTTCATCAAGTAGTCCTA
CTCCTCTCTTCCCTTGGTTTACCCCAGGCTCTCAGACTGAAAGAGGGAGAAATAAAGACAAGGCCCCCGAGGAGCTGTCCAAAGATCGAG
ATGCTGACAAGAGCGTGGAGAAGGACAAGAGTAGAGAGAGAGACCGGGAGAGAGAAAAGGAGAATAAGCGGGAGTCAAGGAAAGAGAAAA
GGAAAAAGGGATCAGAAATTCAGAGTAGTTCTGCTTTGTATCCTGTGGGTAGGGTTTCCAAAGAGAAGGTTGTTGGTGAAGATGTTGCCA
CTTCATCTTCTGCCAAAAAAGCAACAGGGCGGAAGAAGTCTTCATCACATGATTCTGGGACTGATATTACTTCTGTGACTCTTGGGGATA
CAACAGCTGTCAAAACCAAAATACTTATAAAGAAAGGGAGAGGAAATCTGGAAAAAACCAACTTGGACCTCGGCCCAACTGCCCCATCCC
TGGAGAAGGAGAAAACCCTCTGCCTTTCCACTCCTTCATCTAGCACTGTTAAACATTCCACTTCCTCCATAGGCTCCATGTTGGCTCAGG
CAGACAAGCTTCCAATGACTGACAAGAGGGTTGCCAGCCTCCTAAAAAAGGCCAAAGCTCAGCTCTGCAAGATTGAGAAGAGTAAGAGTC
TTAAACAAACCGACCAGCCCAAAGCACAGGGTCAAGAAAGTGACTCATCAGAGACCTCTGTGCGAGGACCCCGGATTAAACATGTCTGCA
GAAGAGCAGCTGTTGCCCTTGGCCGAAAACGAGCTGTGTTTCCTGATGACATGCCCACCCTGAGTGCCTTACCATGGGAAGAACGAGAAA
AGATTTTGTCTTCCATGGGGAATGATGACAAGTCATCAATTGCTGGCTCAGAAGATGCTGAACCTCTTGCTCCACCCATCAAACCAATTA
AACCTGTCACTAGAAACAAGGCACCCCAGGAACCTCCAGTAAAGAAAGGACGTCGATCGAGGCGGTGTGGGCAGTGTCCCGGCTGCCAGG
TGCCTGAGGACTGTGGTGTTTGTACTAATTGCTTAGATAAGCCCAAGTTTGGTGGTCGCAATATAAAGAAGCAGTGCTGCAAGATGAGAA
AATGTCAGAATCTACAATGGATGCCTTCCAAAGCCTACCTGCAGAAGCAAGCTAAAGCTGTGAAAAAGAAAGAGAAAAAGTCTAAGACCA
GTGAAAAGAAAGACAGCAAAGAGAGCAGTGTTGTGAAGAACGTGGTGGACTCTAGTCAGAAACCTACCCCATCAGCAAGAGAGGATCCTG
CCCCAAAGAAAAGCAGTAGTGAGCCTCCTCCACGAAAGCCCGTCGAGGAAAAGAGTGAAGAAGGGAATGTCTCGGCCCCTGGGCCTGAAT
CCAAACAGGCCACCACTCCAGCTTCCAGGAAGTCAAGCAAGCAGGTCTCCCAGCCAGCACTGGTCATCCCGCCTCAGCCACCTACTACAG
GACCGCCAAGAAAAGAAGTTCCCAAAACCACTCCTAGTGAGCCCAAGAAAAAGCAGCCTCCACCACCAGAATCAGGTCCAGAGCAGAGCA
AACAGAAAAAAGTGGCTCCCCGCCCAAGTATCCCTGTAAAACAAAAACCAAAAGAAAAGGAAAAACCACCTCCGGTCAATAAGCAGGAGA
ATGCAGGCACTTTGAACATCCTCAGCACTCTCTCCAATGGCAATAGTTCTAAGCAAAAAATTCCAGCAGATGGAGTCCACAGGATCAGAG
TGGACTTTAAGGACGCCAACAAGGAGAGCAGCAAGACCTCCAAGCCACACAAGGTGACCAAGGAGCACCGGGAGCGGCCCCGCAAAGACT
CCGAGAGCAAGAGCTCCTCCAAGGAGCTGGAGCGTGAGCAGGCCAAAAGCTCCAAGGACACCTCGCGGAAGCTGGGCGAGGGCCGGCTGC
CCAAGGAGGAGAAGGCGCCACCGCCCAAGGCTGCCTTCAAGGAACCCAAGATGGCCCTGAAAGAGACCAAGCTGGAAAGCACGTCCCCCA
AGGGTGGGCCCCCACCCCCACCCCCACCCCCACCCCGGGCTTCCAGCAAGCGGCCGGCCACCGCCGACTCGCCAAAGCCCAGCGCCAAGA
AGCAGAAGAAGAGCAGCTCGAAGGGGTCCCGGAGTGCTCCAGGCACCTCGCCCCGCACCTCCTCCTCCTCCTCCTTCTCGGACAAGAAGC
CGGCCAAGGACAAGAGCAGCACCAGAGGGGAGAAGGTGAAGGCCGAGAGTGAGCCCCGGGAGGCCAAAAAGGCCCTGGAGGTGGAGGAGT
CCAACTCAGAGGACGAGGCCTCCTTCAAGTCCGAGTCTGCCCAGTCAAGCCCGTCCAACTCCAGCTCCAGCTCAGACTCCAGCTCAGACT
CAGACTTCGAGCCATCCCAGAACCACAGCCAAGGACCCCTGCGCTCCATGGTGGAGGACCTGCAGTCCGAGGAGTCCGACGAGGACGACT
CTTCGTCAGGCGAGGAGGCTGCCGGCAAGACCAACCCGGGGAGGGACTCCAGGTTGAGCTTCAGCGACAGCGAGAGTGACAACAGCGCCG
ACTCCTCCCTGCCCAGCCGTGAGCCCCCACCCCCCCAGAAGCCACCCCCGCCCAACAGCAAGGTGTCAGGCCGGAGGAGCCCCGAGTCCT
GCAGCAAGCCTGAGAAGATCCTCAAGAAGGGCACCTACGACAAGGCCTACACGGATGAGCTGGTGGAGCTACACCGGAGGCTGATGGCGC
TGCGGGAGCGCAACGTGCTGCAGCAGATTGTGAATCTGATCGAGGAGACTGGCCACTTCAATGTCACCAACACCACCTTCGACTTCGACC
TCTTCTCCCTGGACGAGACCACCGTGCGCAAACTGCAGAGCTGCCTGGAGGCCGTGGCCACATGACCCTGGGCCGCGTGCCGGGCCCCCA

>In-frame_ENST00000534358_ENST00000252674_DQ224341_KMT2A_chr11_118355030_+_MLLT1_chr19_6222697_length(amino acids)=1783AA_start in transcript=23_stop in transcript=5374
MAHSCRWRFPARPGTTGGGGGGGRRGLGGAPRQRVPALLLPPGPPVGGGGPGAPPSPPAVAAAAAAAGSSGAGVPGGAAAASAASSSSAS
SSSSSSSSASSGPALLRVGPGFDAALQVSAAIGTNLRRFRAVFGESGGGGGSGEDEQFLGFGSDEEVRVRSPTRSPSVKTSPRKPRGRPR
SGSDRNSAILSDPSVFSPLNKSETKSGDKIKKKDSKSIEKKRGRPPTFPGVKIKITHGKDISELPKGNKEDSLKKIKRTPSATFQQATKI
KKLRAGKLSPLKSKFKTGKLQIGRKGVQIVRRRGRPPSTERIKTPSGLLINSELEKPQKVRKDKEGTPPLTKEDKTVVRQSPRRIKPVRI
IPSSKRTDATIAKQLLQRAKKGAQKKIEKEAAQLQGRKVKTQVKNIRQFIMPVVSAISSRIIKTPRRFIEDEDYDPPIKIARLESTPNSR
FSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGS
RTTKKLSTLQSAPQQQTSSSPPPPLLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQ
YFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSN
RTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESA
EKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQ
SSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKILIKKGRGNLEKTNLDLGPTAPSLEKEKTLC
LSTPSSSTVKHSTSSIGSMLAQADKLPMTDKRVASLLKKAKAQLCKIEKSKSLKQTDQPKAQGQESDSSETSVRGPRIKHVCRRAAVALG
RKRAVFPDDMPTLSALPWEEREKILSSMGNDDKSSIAGSEDAEPLAPPIKPIKPVTRNKAPQEPPVKKGRRSRRCGQCPGCQVPEDCGVC
TNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKSSSE
PPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPR
PSIPVKQKPKEKEKPPPVNKQENAGTLNILSTLSNGNSSKQKIPADGVHRIRVDFKDANKESSKTSKPHKVTKEHRERPRKDSESKSSSK
ELEREQAKSSKDTSRKLGEGRLPKEEKAPPPKAAFKEPKMALKETKLESTSPKGGPPPPPPPPPRASSKRPATADSPKPSAKKQKKSSSK
GSRSAPGTSPRTSSSSSFSDKKPAKDKSSTRGEKVKAESEPREAKKALEVEESNSEDEASFKSESAQSSPSNSSSSSDSSSDSDFEPSQN
HSQGPLRSMVEDLQSEESDEDDSSSGEEAAGKTNPGRDSRLSFSDSESDNSADSSLPSREPPPPQKPPPPNSKVSGRRSPESCSKPEKIL

--------------------------------------------------------------
>In-frame_ENST00000389506_ENST00000252674_DQ224341_KMT2A_chr11_118355030_+_MLLT1_chr19_6222697_length(transcript)=5439nt_BP=4218nt
ATGGCGCACAGCTGTCGGTGGCGCTTCCCCGCCCGACCCGGGACCACCGGGGGCGGCGGCGGCGGGGGGCGCCGGGGCCTAGGGGGCGCC
CCGCGGCAACGCGTCCCGGCCCTGCTGCTTCCCCCCGGGCCCCCGGTCGGCGGTGGCGGCCCCGGGGCGCCCCCCTCCCCCCCGGCTGTG
GCGGCCGCGGCGGCGGCGGCGGGAAGCAGCGGGGCTGGGGTTCCAGGGGGAGCGGCCGCCGCCTCAGCAGCCTCCTCGTCGTCCGCCTCG
TCTTCGTCTTCGTCATCGTCCTCAGCCTCTTCAGGGCCGGCCCTGCTCCGGGTGGGCCCGGGCTTCGACGCGGCGCTGCAGGTCTCGGCC
GCCATCGGCACCAACCTGCGCCGGTTCCGGGCCGTGTTTGGGGAGAGCGGCGGGGGAGGCGGCAGCGGAGAGGATGAGCAATTCTTAGGT
TTTGGCTCAGATGAAGAAGTCAGAGTGCGAAGTCCCACAAGGTCTCCTTCAGTTAAAACTAGTCCTCGAAAACCTCGTGGGAGACCTAGA
AGTGGCTCTGACCGAAATTCAGCTATCCTCTCAGATCCATCTGTGTTTTCCCCTCTAAATAAATCAGAGACCAAATCTGGAGATAAGATC
AAGAAGAAAGATTCTAAAAGTATAGAAAAGAAGAGAGGAAGACCTCCCACCTTCCCTGGAGTAAAAATCAAAATAACACATGGAAAGGAC
ATTTCAGAGTTACCAAAGGGAAACAAAGAAGATAGCCTGAAAAAAATTAAAAGGACACCTTCTGCTACGTTTCAGCAAGCCACAAAGATT
AAAAAATTAAGAGCAGGTAAACTCTCTCCTCTCAAGTCTAAGTTTAAGACAGGGAAGCTTCAAATAGGAAGGAAGGGGGTACAAATTGTA
CGACGGAGAGGAAGGCCTCCATCAACAGAAAGGATAAAGACCCCTTCGGGTCTCCTCATTAATTCTGAACTGGAAAAGCCCCAGAAAGTC
CGGAAAGACAAGGAAGGAACACCTCCACTTACAAAAGAAGATAAGACAGTTGTCAGACAAAGCCCTCGAAGGATTAAGCCAGTTAGGATT
ATTCCTTCTTCAAAAAGGACAGATGCAACCATTGCTAAGCAACTCTTACAGAGGGCAAAAAAGGGGGCTCAAAAGAAAATTGAAAAAGAA
GCAGCTCAGCTGCAGGGAAGAAAGGTGAAGACACAGGTCAAAAATATTCGACAGTTCATCATGCCTGTTGTCAGTGCTATCTCCTCGCGG
ATCATTAAGACCCCTCGGCGGTTTATAGAGGATGAGGATTATGACCCTCCAATTAAAATTGCCCGATTAGAGTCTACACCGAATAGTAGA
TTCAGTGCCCCGTCCTGTGGATCTTCTGAAAAATCAAGTGCAGCTTCTCAGCACTCCTCTCAAATGTCTTCAGACTCCTCTCGATCTAGT
AGCCCCAGTGTTGATACCTCCACAGACTCTCAGGCTTCTGAGGAGATTCAGGTACTTCCTGAGGAGCGGAGCGATACCCCTGAAGTTCAT
CCTCCACTGCCCATTTCCCAGTCCCCAGAAAATGAGAGTAATGATAGGAGAAGCAGAAGGTATTCAGTGTCGGAGAGAAGTTTTGGATCT
AGAACGACGAAAAAATTATCAACTCTACAAAGTGCCCCCCAGCAGCAGACCTCCTCGTCTCCACCTCCACCTCTGCTGACTCCACCGCCA
CCACTGCAGCCAGCCTCCAGTATCTCTGACCACACACCTTGGCTTATGCCTCCAACAATCCCCTTAGCATCACCATTTTTGCCTGCTTCC
ACTGCTCCTATGCAAGGGAAGCGAAAATCTATTTTGCGAGAACCGACATTTAGGTGGACTTCTTTAAAGCATTCTAGGTCAGAGCCACAA
TACTTTTCCTCAGCAAAGTATGCCAAAGAAGGTCTTATTCGCAAACCAATATTTGATAATTTCCGACCCCCTCCACTAACTCCCGAGGAC
GTTGGCTTTGCATCTGGTTTTTCTGCATCTGGTACCGCTGCTTCAGCCCGATTGTTTTCGCCACTCCATTCTGGAACAAGGTTTGATATG
CACAAAAGGAGCCCTCTTCTGAGAGCTCCAAGATTTACTCCAAGTGAGGCTCACTCTAGAATATTTGAGTCTGTAACCTTGCCTAGTAAT
CGAACTTCTGCTGGAACATCTTCTTCAGGAGTATCCAATAGAAAAAGGAAAAGAAAAGTGTTTAGTCCTATTCGATCTGAACCAAGATCT
CCTTCTCACTCCATGAGGACAAGAAGTGGAAGGCTTAGTAGTTCTGAGCTCTCACCTCTCACCCCCCCGTCTTCTGTCTCTTCCTCGTTA
AGCATTTCTGTTAGTCCTCTTGCCACTAGTGCCTTAAACCCAACTTTTACTTTTCCTTCTCATTCCCTGACTCAGTCTGGGGAATCTGCA
GAGAAAAATCAGAGACCAAGGAAGCAGACTAGTGCTCCGGCAGAGCCATTTTCATCAAGTAGTCCTACTCCTCTCTTCCCTTGGTTTACC
CCAGGCTCTCAGACTGAAAGAGGGAGAAATAAAGACAAGGCCCCCGAGGAGCTGTCCAAAGATCGAGATGCTGACAAGAGCGTGGAGAAG
GACAAGAGTAGAGAGAGAGACCGGGAGAGAGAAAAGGAGAATAAGCGGGAGTCAAGGAAAGAGAAAAGGAAAAAGGGATCAGAAATTCAG
AGTAGTTCTGCTTTGTATCCTGTGGGTAGGGTTTCCAAAGAGAAGGTTGTTGGTGAAGATGTTGCCACTTCATCTTCTGCCAAAAAAGCA
ACAGGGCGGAAGAAGTCTTCATCACATGATTCTGGGACTGATATTACTTCTGTGACTCTTGGGGATACAACAGCTGTCAAAACCAAAATA
CTTATAAAGAAAGGGAGAGGAAATCTGGAAAAAACCAACTTGGACCTCGGCCCAACTGCCCCATCCCTGGAGAAGGAGAAAACCCTCTGC
CTTTCCACTCCTTCATCTAGCACTGTTAAACATTCCACTTCCTCCATAGGCTCCATGTTGGCTCAGGCAGACAAGCTTCCAATGACTGAC
AAGAGGGTTGCCAGCCTCCTAAAAAAGGCCAAAGCTCAGCTCTGCAAGATTGAGAAGAGTAAGAGTCTTAAACAAACCGACCAGCCCAAA
GCACAGGGTCAAGAAAGTGACTCATCAGAGACCTCTGTGCGAGGACCCCGGATTAAACATGTCTGCAGAAGAGCAGCTGTTGCCCTTGGC
CGAAAACGAGCTGTGTTTCCTGATGACATGCCCACCCTGAGTGCCTTACCATGGGAAGAACGAGAAAAGATTTTGTCTTCCATGGGGAAT
GATGACAAGTCATCAATTGCTGGCTCAGAAGATGCTGAACCTCTTGCTCCACCCATCAAACCAATTAAACCTGTCACTAGAAACAAGGCA
CCCCAGGAACCTCCAGTAAAGAAAGGACGTCGATCGAGGCGGTGTGGGCAGTGTCCCGGCTGCCAGGTGCCTGAGGACTGTGGTGTTTGT
ACTAATTGCTTAGATAAGCCCAAGTTTGGTGGTCGCAATATAAAGAAGCAGTGCTGCAAGATGAGAAAATGTCAGAATCTACAATGGATG
CCTTCCAAAGCCTACCTGCAGAAGCAAGCTAAAGCTGTGAAAAAGAAAGAGAAAAAGTCTAAGACCAGTGAAAAGAAAGACAGCAAAGAG
AGCAGTGTTGTGAAGAACGTGGTGGACTCTAGTCAGAAACCTACCCCATCAGCAAGAGAGGATCCTGCCCCAAAGAAAAGCAGTAGTGAG
CCTCCTCCACGAAAGCCCGTCGAGGAAAAGAGTGAAGAAGGGAATGTCTCGGCCCCTGGGCCTGAATCCAAACAGGCCACCACTCCAGCT
TCCAGGAAGTCAAGCAAGCAGGTCTCCCAGCCAGCACTGGTCATCCCGCCTCAGCCACCTACTACAGGACCGCCAAGAAAAGAAGTTCCC
AAAACCACTCCTAGTGAGCCCAAGAAAAAGCAGCCTCCACCACCAGAATCAGGTCCAGAGCAGAGCAAACAGAAAAAAGTGGCTCCCCGC
CCAAGTATCCCTGTAAAACAAAAACCAAAAGAAAAGGAAAAACCACCTCCGGTCAATAAGCAGGAGAATGCAGGCACTTTGAACATCCTC
AGCACTCTCTCCAATGGCAATAGTTCTAAGCAAAAAATTCCAGCAGATGGAGTCCACAGGATCAGAGTGGACTTTAAGGACGCCAACAAG
GAGAGCAGCAAGACCTCCAAGCCACACAAGGTGACCAAGGAGCACCGGGAGCGGCCCCGCAAAGACTCCGAGAGCAAGAGCTCCTCCAAG
GAGCTGGAGCGTGAGCAGGCCAAAAGCTCCAAGGACACCTCGCGGAAGCTGGGCGAGGGCCGGCTGCCCAAGGAGGAGAAGGCGCCACCG
CCCAAGGCTGCCTTCAAGGAACCCAAGATGGCCCTGAAAGAGACCAAGCTGGAAAGCACGTCCCCCAAGGGTGGGCCCCCACCCCCACCC
CCACCCCCACCCCGGGCTTCCAGCAAGCGGCCGGCCACCGCCGACTCGCCAAAGCCCAGCGCCAAGAAGCAGAAGAAGAGCAGCTCGAAG
GGGTCCCGGAGTGCTCCAGGCACCTCGCCCCGCACCTCCTCCTCCTCCTCCTTCTCGGACAAGAAGCCGGCCAAGGACAAGAGCAGCACC
AGAGGGGAGAAGGTGAAGGCCGAGAGTGAGCCCCGGGAGGCCAAAAAGGCCCTGGAGGTGGAGGAGTCCAACTCAGAGGACGAGGCCTCC
TTCAAGTCCGAGTCTGCCCAGTCAAGCCCGTCCAACTCCAGCTCCAGCTCAGACTCCAGCTCAGACTCAGACTTCGAGCCATCCCAGAAC
CACAGCCAAGGACCCCTGCGCTCCATGGTGGAGGACCTGCAGTCCGAGGAGTCCGACGAGGACGACTCTTCGTCAGGCGAGGAGGCTGCC
GGCAAGACCAACCCGGGGAGGGACTCCAGGTTGAGCTTCAGCGACAGCGAGAGTGACAACAGCGCCGACTCCTCCCTGCCCAGCCGTGAG
CCCCCACCCCCCCAGAAGCCACCCCCGCCCAACAGCAAGGTGTCAGGCCGGAGGAGCCCCGAGTCCTGCAGCAAGCCTGAGAAGATCCTC
AAGAAGGGCACCTACGACAAGGCCTACACGGATGAGCTGGTGGAGCTACACCGGAGGCTGATGGCGCTGCGGGAGCGCAACGTGCTGCAG
CAGATTGTGAATCTGATCGAGGAGACTGGCCACTTCAATGTCACCAACACCACCTTCGACTTCGACCTCTTCTCCCTGGACGAGACCACC
GTGCGCAAACTGCAGAGCTGCCTGGAGGCCGTGGCCACATGACCCTGGGCCGCGTGCCGGGCCCCCACCGCCGGGGTCCTGGGAGGCTGC

>In-frame_ENST00000389506_ENST00000252674_DQ224341_KMT2A_chr11_118355030_+_MLLT1_chr19_6222697_length(amino acids)=1783AA_start in transcript=0_stop in transcript=5351
MAHSCRWRFPARPGTTGGGGGGGRRGLGGAPRQRVPALLLPPGPPVGGGGPGAPPSPPAVAAAAAAAGSSGAGVPGGAAAASAASSSSAS
SSSSSSSSASSGPALLRVGPGFDAALQVSAAIGTNLRRFRAVFGESGGGGGSGEDEQFLGFGSDEEVRVRSPTRSPSVKTSPRKPRGRPR
SGSDRNSAILSDPSVFSPLNKSETKSGDKIKKKDSKSIEKKRGRPPTFPGVKIKITHGKDISELPKGNKEDSLKKIKRTPSATFQQATKI
KKLRAGKLSPLKSKFKTGKLQIGRKGVQIVRRRGRPPSTERIKTPSGLLINSELEKPQKVRKDKEGTPPLTKEDKTVVRQSPRRIKPVRI
IPSSKRTDATIAKQLLQRAKKGAQKKIEKEAAQLQGRKVKTQVKNIRQFIMPVVSAISSRIIKTPRRFIEDEDYDPPIKIARLESTPNSR
FSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGS
RTTKKLSTLQSAPQQQTSSSPPPPLLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQ
YFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSN
RTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESA
EKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQ
SSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKILIKKGRGNLEKTNLDLGPTAPSLEKEKTLC
LSTPSSSTVKHSTSSIGSMLAQADKLPMTDKRVASLLKKAKAQLCKIEKSKSLKQTDQPKAQGQESDSSETSVRGPRIKHVCRRAAVALG
RKRAVFPDDMPTLSALPWEEREKILSSMGNDDKSSIAGSEDAEPLAPPIKPIKPVTRNKAPQEPPVKKGRRSRRCGQCPGCQVPEDCGVC
TNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKSSSE
PPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPR
PSIPVKQKPKEKEKPPPVNKQENAGTLNILSTLSNGNSSKQKIPADGVHRIRVDFKDANKESSKTSKPHKVTKEHRERPRKDSESKSSSK
ELEREQAKSSKDTSRKLGEGRLPKEEKAPPPKAAFKEPKMALKETKLESTSPKGGPPPPPPPPPRASSKRPATADSPKPSAKKQKKSSSK
GSRSAPGTSPRTSSSSSFSDKKPAKDKSSTRGEKVKAESEPREAKKALEVEESNSEDEASFKSESAQSSPSNSSSSSDSSSDSDFEPSQN
HSQGPLRSMVEDLQSEESDEDDSSSGEEAAGKTNPGRDSRLSFSDSESDNSADSSLPSREPPPPQKPPPPNSKVSGRRSPESCSKPEKIL

--------------------------------------------------------------
>In-frame_ENST00000354520_ENST00000252674_DQ224341_KMT2A_chr11_118355030_+_MLLT1_chr19_6222697_length(transcript)=5439nt_BP=4218nt
ATGGCGCACAGCTGTCGGTGGCGCTTCCCCGCCCGACCCGGGACCACCGGGGGCGGCGGCGGCGGGGGGCGCCGGGGCCTAGGGGGCGCC
CCGCGGCAACGCGTCCCGGCCCTGCTGCTTCCCCCCGGGCCCCCGGTCGGCGGTGGCGGCCCCGGGGCGCCCCCCTCCCCCCCGGCTGTG
GCGGCCGCGGCGGCGGCGGCGGGAAGCAGCGGGGCTGGGGTTCCAGGGGGAGCGGCCGCCGCCTCAGCAGCCTCCTCGTCGTCCGCCTCG
TCTTCGTCTTCGTCATCGTCCTCAGCCTCTTCAGGGCCGGCCCTGCTCCGGGTGGGCCCGGGCTTCGACGCGGCGCTGCAGGTCTCGGCC
GCCATCGGCACCAACCTGCGCCGGTTCCGGGCCGTGTTTGGGGAGAGCGGCGGGGGAGGCGGCAGCGGAGAGGATGAGCAATTCTTAGGT
TTTGGCTCAGATGAAGAAGTCAGAGTGCGAAGTCCCACAAGGTCTCCTTCAGTTAAAACTAGTCCTCGAAAACCTCGTGGGAGACCTAGA
AGTGGCTCTGACCGAAATTCAGCTATCCTCTCAGATCCATCTGTGTTTTCCCCTCTAAATAAATCAGAGACCAAATCTGGAGATAAGATC
AAGAAGAAAGATTCTAAAAGTATAGAAAAGAAGAGAGGAAGACCTCCCACCTTCCCTGGAGTAAAAATCAAAATAACACATGGAAAGGAC
ATTTCAGAGTTACCAAAGGGAAACAAAGAAGATAGCCTGAAAAAAATTAAAAGGACACCTTCTGCTACGTTTCAGCAAGCCACAAAGATT
AAAAAATTAAGAGCAGGTAAACTCTCTCCTCTCAAGTCTAAGTTTAAGACAGGGAAGCTTCAAATAGGAAGGAAGGGGGTACAAATTGTA
CGACGGAGAGGAAGGCCTCCATCAACAGAAAGGATAAAGACCCCTTCGGGTCTCCTCATTAATTCTGAACTGGAAAAGCCCCAGAAAGTC
CGGAAAGACAAGGAAGGAACACCTCCACTTACAAAAGAAGATAAGACAGTTGTCAGACAAAGCCCTCGAAGGATTAAGCCAGTTAGGATT
ATTCCTTCTTCAAAAAGGACAGATGCAACCATTGCTAAGCAACTCTTACAGAGGGCAAAAAAGGGGGCTCAAAAGAAAATTGAAAAAGAA
GCAGCTCAGCTGCAGGGAAGAAAGGTGAAGACACAGGTCAAAAATATTCGACAGTTCATCATGCCTGTTGTCAGTGCTATCTCCTCGCGG
ATCATTAAGACCCCTCGGCGGTTTATAGAGGATGAGGATTATGACCCTCCAATTAAAATTGCCCGATTAGAGTCTACACCGAATAGTAGA
TTCAGTGCCCCGTCCTGTGGATCTTCTGAAAAATCAAGTGCAGCTTCTCAGCACTCCTCTCAAATGTCTTCAGACTCCTCTCGATCTAGT
AGCCCCAGTGTTGATACCTCCACAGACTCTCAGGCTTCTGAGGAGATTCAGGTACTTCCTGAGGAGCGGAGCGATACCCCTGAAGTTCAT
CCTCCACTGCCCATTTCCCAGTCCCCAGAAAATGAGAGTAATGATAGGAGAAGCAGAAGGTATTCAGTGTCGGAGAGAAGTTTTGGATCT
AGAACGACGAAAAAATTATCAACTCTACAAAGTGCCCCCCAGCAGCAGACCTCCTCGTCTCCACCTCCACCTCTGCTGACTCCACCGCCA
CCACTGCAGCCAGCCTCCAGTATCTCTGACCACACACCTTGGCTTATGCCTCCAACAATCCCCTTAGCATCACCATTTTTGCCTGCTTCC
ACTGCTCCTATGCAAGGGAAGCGAAAATCTATTTTGCGAGAACCGACATTTAGGTGGACTTCTTTAAAGCATTCTAGGTCAGAGCCACAA
TACTTTTCCTCAGCAAAGTATGCCAAAGAAGGTCTTATTCGCAAACCAATATTTGATAATTTCCGACCCCCTCCACTAACTCCCGAGGAC
GTTGGCTTTGCATCTGGTTTTTCTGCATCTGGTACCGCTGCTTCAGCCCGATTGTTTTCGCCACTCCATTCTGGAACAAGGTTTGATATG
CACAAAAGGAGCCCTCTTCTGAGAGCTCCAAGATTTACTCCAAGTGAGGCTCACTCTAGAATATTTGAGTCTGTAACCTTGCCTAGTAAT
CGAACTTCTGCTGGAACATCTTCTTCAGGAGTATCCAATAGAAAAAGGAAAAGAAAAGTGTTTAGTCCTATTCGATCTGAACCAAGATCT
CCTTCTCACTCCATGAGGACAAGAAGTGGAAGGCTTAGTAGTTCTGAGCTCTCACCTCTCACCCCCCCGTCTTCTGTCTCTTCCTCGTTA
AGCATTTCTGTTAGTCCTCTTGCCACTAGTGCCTTAAACCCAACTTTTACTTTTCCTTCTCATTCCCTGACTCAGTCTGGGGAATCTGCA
GAGAAAAATCAGAGACCAAGGAAGCAGACTAGTGCTCCGGCAGAGCCATTTTCATCAAGTAGTCCTACTCCTCTCTTCCCTTGGTTTACC
CCAGGCTCTCAGACTGAAAGAGGGAGAAATAAAGACAAGGCCCCCGAGGAGCTGTCCAAAGATCGAGATGCTGACAAGAGCGTGGAGAAG
GACAAGAGTAGAGAGAGAGACCGGGAGAGAGAAAAGGAGAATAAGCGGGAGTCAAGGAAAGAGAAAAGGAAAAAGGGATCAGAAATTCAG
AGTAGTTCTGCTTTGTATCCTGTGGGTAGGGTTTCCAAAGAGAAGGTTGTTGGTGAAGATGTTGCCACTTCATCTTCTGCCAAAAAAGCA
ACAGGGCGGAAGAAGTCTTCATCACATGATTCTGGGACTGATATTACTTCTGTGACTCTTGGGGATACAACAGCTGTCAAAACCAAAATA
CTTATAAAGAAAGGGAGAGGAAATCTGGAAAAAACCAACTTGGACCTCGGCCCAACTGCCCCATCCCTGGAGAAGGAGAAAACCCTCTGC
CTTTCCACTCCTTCATCTAGCACTGTTAAACATTCCACTTCCTCCATAGGCTCCATGTTGGCTCAGGCAGACAAGCTTCCAATGACTGAC
AAGAGGGTTGCCAGCCTCCTAAAAAAGGCCAAAGCTCAGCTCTGCAAGATTGAGAAGAGTAAGAGTCTTAAACAAACCGACCAGCCCAAA
GCACAGGGTCAAGAAAGTGACTCATCAGAGACCTCTGTGCGAGGACCCCGGATTAAACATGTCTGCAGAAGAGCAGCTGTTGCCCTTGGC
CGAAAACGAGCTGTGTTTCCTGATGACATGCCCACCCTGAGTGCCTTACCATGGGAAGAACGAGAAAAGATTTTGTCTTCCATGGGGAAT
GATGACAAGTCATCAATTGCTGGCTCAGAAGATGCTGAACCTCTTGCTCCACCCATCAAACCAATTAAACCTGTCACTAGAAACAAGGCA
CCCCAGGAACCTCCAGTAAAGAAAGGACGTCGATCGAGGCGGTGTGGGCAGTGTCCCGGCTGCCAGGTGCCTGAGGACTGTGGTGTTTGT
ACTAATTGCTTAGATAAGCCCAAGTTTGGTGGTCGCAATATAAAGAAGCAGTGCTGCAAGATGAGAAAATGTCAGAATCTACAATGGATG
CCTTCCAAAGCCTACCTGCAGAAGCAAGCTAAAGCTGTGAAAAAGAAAGAGAAAAAGTCTAAGACCAGTGAAAAGAAAGACAGCAAAGAG
AGCAGTGTTGTGAAGAACGTGGTGGACTCTAGTCAGAAACCTACCCCATCAGCAAGAGAGGATCCTGCCCCAAAGAAAAGCAGTAGTGAG
CCTCCTCCACGAAAGCCCGTCGAGGAAAAGAGTGAAGAAGGGAATGTCTCGGCCCCTGGGCCTGAATCCAAACAGGCCACCACTCCAGCT
TCCAGGAAGTCAAGCAAGCAGGTCTCCCAGCCAGCACTGGTCATCCCGCCTCAGCCACCTACTACAGGACCGCCAAGAAAAGAAGTTCCC
AAAACCACTCCTAGTGAGCCCAAGAAAAAGCAGCCTCCACCACCAGAATCAGGTCCAGAGCAGAGCAAACAGAAAAAAGTGGCTCCCCGC
CCAAGTATCCCTGTAAAACAAAAACCAAAAGAAAAGGAAAAACCACCTCCGGTCAATAAGCAGGAGAATGCAGGCACTTTGAACATCCTC
AGCACTCTCTCCAATGGCAATAGTTCTAAGCAAAAAATTCCAGCAGATGGAGTCCACAGGATCAGAGTGGACTTTAAGGACGCCAACAAG
GAGAGCAGCAAGACCTCCAAGCCACACAAGGTGACCAAGGAGCACCGGGAGCGGCCCCGCAAAGACTCCGAGAGCAAGAGCTCCTCCAAG
GAGCTGGAGCGTGAGCAGGCCAAAAGCTCCAAGGACACCTCGCGGAAGCTGGGCGAGGGCCGGCTGCCCAAGGAGGAGAAGGCGCCACCG
CCCAAGGCTGCCTTCAAGGAACCCAAGATGGCCCTGAAAGAGACCAAGCTGGAAAGCACGTCCCCCAAGGGTGGGCCCCCACCCCCACCC
CCACCCCCACCCCGGGCTTCCAGCAAGCGGCCGGCCACCGCCGACTCGCCAAAGCCCAGCGCCAAGAAGCAGAAGAAGAGCAGCTCGAAG
GGGTCCCGGAGTGCTCCAGGCACCTCGCCCCGCACCTCCTCCTCCTCCTCCTTCTCGGACAAGAAGCCGGCCAAGGACAAGAGCAGCACC
AGAGGGGAGAAGGTGAAGGCCGAGAGTGAGCCCCGGGAGGCCAAAAAGGCCCTGGAGGTGGAGGAGTCCAACTCAGAGGACGAGGCCTCC
TTCAAGTCCGAGTCTGCCCAGTCAAGCCCGTCCAACTCCAGCTCCAGCTCAGACTCCAGCTCAGACTCAGACTTCGAGCCATCCCAGAAC
CACAGCCAAGGACCCCTGCGCTCCATGGTGGAGGACCTGCAGTCCGAGGAGTCCGACGAGGACGACTCTTCGTCAGGCGAGGAGGCTGCC
GGCAAGACCAACCCGGGGAGGGACTCCAGGTTGAGCTTCAGCGACAGCGAGAGTGACAACAGCGCCGACTCCTCCCTGCCCAGCCGTGAG
CCCCCACCCCCCCAGAAGCCACCCCCGCCCAACAGCAAGGTGTCAGGCCGGAGGAGCCCCGAGTCCTGCAGCAAGCCTGAGAAGATCCTC
AAGAAGGGCACCTACGACAAGGCCTACACGGATGAGCTGGTGGAGCTACACCGGAGGCTGATGGCGCTGCGGGAGCGCAACGTGCTGCAG
CAGATTGTGAATCTGATCGAGGAGACTGGCCACTTCAATGTCACCAACACCACCTTCGACTTCGACCTCTTCTCCCTGGACGAGACCACC
GTGCGCAAACTGCAGAGCTGCCTGGAGGCCGTGGCCACATGACCCTGGGCCGCGTGCCGGGCCCCCACCGCCGGGGTCCTGGGAGGCTGC

>In-frame_ENST00000354520_ENST00000252674_DQ224341_KMT2A_chr11_118355030_+_MLLT1_chr19_6222697_length(amino acids)=1783AA_start in transcript=0_stop in transcript=5351
MAHSCRWRFPARPGTTGGGGGGGRRGLGGAPRQRVPALLLPPGPPVGGGGPGAPPSPPAVAAAAAAAGSSGAGVPGGAAAASAASSSSAS
SSSSSSSSASSGPALLRVGPGFDAALQVSAAIGTNLRRFRAVFGESGGGGGSGEDEQFLGFGSDEEVRVRSPTRSPSVKTSPRKPRGRPR
SGSDRNSAILSDPSVFSPLNKSETKSGDKIKKKDSKSIEKKRGRPPTFPGVKIKITHGKDISELPKGNKEDSLKKIKRTPSATFQQATKI
KKLRAGKLSPLKSKFKTGKLQIGRKGVQIVRRRGRPPSTERIKTPSGLLINSELEKPQKVRKDKEGTPPLTKEDKTVVRQSPRRIKPVRI
IPSSKRTDATIAKQLLQRAKKGAQKKIEKEAAQLQGRKVKTQVKNIRQFIMPVVSAISSRIIKTPRRFIEDEDYDPPIKIARLESTPNSR
FSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGS
RTTKKLSTLQSAPQQQTSSSPPPPLLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQ
YFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSN
RTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESA
EKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQ
SSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKILIKKGRGNLEKTNLDLGPTAPSLEKEKTLC
LSTPSSSTVKHSTSSIGSMLAQADKLPMTDKRVASLLKKAKAQLCKIEKSKSLKQTDQPKAQGQESDSSETSVRGPRIKHVCRRAAVALG
RKRAVFPDDMPTLSALPWEEREKILSSMGNDDKSSIAGSEDAEPLAPPIKPIKPVTRNKAPQEPPVKKGRRSRRCGQCPGCQVPEDCGVC
TNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKSSSE
PPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPR
PSIPVKQKPKEKEKPPPVNKQENAGTLNILSTLSNGNSSKQKIPADGVHRIRVDFKDANKESSKTSKPHKVTKEHRERPRKDSESKSSSK
ELEREQAKSSKDTSRKLGEGRLPKEEKAPPPKAAFKEPKMALKETKLESTSPKGGPPPPPPPPPRASSKRPATADSPKPSAKKQKKSSSK
GSRSAPGTSPRTSSSSSFSDKKPAKDKSSTRGEKVKAESEPREAKKALEVEESNSEDEASFKSESAQSSPSNSSSSSDSSSDSDFEPSQN
HSQGPLRSMVEDLQSEESDEDDSSSGEEAAGKTNPGRDSRLSFSDSESDNSADSSLPSREPPPPQKPPPPNSKVSGRRSPESCSKPEKIL

--------------------------------------------------------------
>In-frame_ENST00000534358_ENST00000252674_DQ224342_KMT2A_chr11_118355691_+_MLLT1_chr19_6222697_length(transcript)=5576nt_BP=4355nt
CTGCTTCACTTCACGGGGCGAACATGGCGCACAGCTGTCGGTGGCGCTTCCCCGCCCGACCCGGGACCACCGGGGGCGGCGGCGGCGGGG
GGCGCCGGGGCCTAGGGGGCGCCCCGCGGCAACGCGTCCCGGCCCTGCTGCTTCCCCCCGGGCCCCCGGTCGGCGGTGGCGGCCCCGGGG
CGCCCCCCTCCCCCCCGGCTGTGGCGGCCGCGGCGGCGGCGGCGGGAAGCAGCGGGGCTGGGGTTCCAGGGGGAGCGGCCGCCGCCTCAG
CAGCCTCCTCGTCGTCCGCCTCGTCTTCGTCTTCGTCATCGTCCTCAGCCTCTTCAGGGCCGGCCCTGCTCCGGGTGGGCCCGGGCTTCG
ACGCGGCGCTGCAGGTCTCGGCCGCCATCGGCACCAACCTGCGCCGGTTCCGGGCCGTGTTTGGGGAGAGCGGCGGGGGAGGCGGCAGCG
GAGAGGATGAGCAATTCTTAGGTTTTGGCTCAGATGAAGAAGTCAGAGTGCGAAGTCCCACAAGGTCTCCTTCAGTTAAAACTAGTCCTC
GAAAACCTCGTGGGAGACCTAGAAGTGGCTCTGACCGAAATTCAGCTATCCTCTCAGATCCATCTGTGTTTTCCCCTCTAAATAAATCAG
AGACCAAATCTGGAGATAAGATCAAGAAGAAAGATTCTAAAAGTATAGAAAAGAAGAGAGGAAGACCTCCCACCTTCCCTGGAGTAAAAA
TCAAAATAACACATGGAAAGGACATTTCAGAGTTACCAAAGGGAAACAAAGAAGATAGCCTGAAAAAAATTAAAAGGACACCTTCTGCTA
CGTTTCAGCAAGCCACAAAGATTAAAAAATTAAGAGCAGGTAAACTCTCTCCTCTCAAGTCTAAGTTTAAGACAGGGAAGCTTCAAATAG
GAAGGAAGGGGGTACAAATTGTACGACGGAGAGGAAGGCCTCCATCAACAGAAAGGATAAAGACCCCTTCGGGTCTCCTCATTAATTCTG
AACTGGAAAAGCCCCAGAAAGTCCGGAAAGACAAGGAAGGAACACCTCCACTTACAAAAGAAGATAAGACAGTTGTCAGACAAAGCCCTC
GAAGGATTAAGCCAGTTAGGATTATTCCTTCTTCAAAAAGGACAGATGCAACCATTGCTAAGCAACTCTTACAGAGGGCAAAAAAGGGGG
CTCAAAAGAAAATTGAAAAAGAAGCAGCTCAGCTGCAGGGAAGAAAGGTGAAGACACAGGTCAAAAATATTCGACAGTTCATCATGCCTG
TTGTCAGTGCTATCTCCTCGCGGATCATTAAGACCCCTCGGCGGTTTATAGAGGATGAGGATTATGACCCTCCAATTAAAATTGCCCGAT
TAGAGTCTACACCGAATAGTAGATTCAGTGCCCCGTCCTGTGGATCTTCTGAAAAATCAAGTGCAGCTTCTCAGCACTCCTCTCAAATGT
CTTCAGACTCCTCTCGATCTAGTAGCCCCAGTGTTGATACCTCCACAGACTCTCAGGCTTCTGAGGAGATTCAGGTACTTCCTGAGGAGC
GGAGCGATACCCCTGAAGTTCATCCTCCACTGCCCATTTCCCAGTCCCCAGAAAATGAGAGTAATGATAGGAGAAGCAGAAGGTATTCAG
TGTCGGAGAGAAGTTTTGGATCTAGAACGACGAAAAAATTATCAACTCTACAAAGTGCCCCCCAGCAGCAGACCTCCTCGTCTCCACCTC
CACCTCTGCTGACTCCACCGCCACCACTGCAGCCAGCCTCCAGTATCTCTGACCACACACCTTGGCTTATGCCTCCAACAATCCCCTTAG
CATCACCATTTTTGCCTGCTTCCACTGCTCCTATGCAAGGGAAGCGAAAATCTATTTTGCGAGAACCGACATTTAGGTGGACTTCTTTAA
AGCATTCTAGGTCAGAGCCACAATACTTTTCCTCAGCAAAGTATGCCAAAGAAGGTCTTATTCGCAAACCAATATTTGATAATTTCCGAC
CCCCTCCACTAACTCCCGAGGACGTTGGCTTTGCATCTGGTTTTTCTGCATCTGGTACCGCTGCTTCAGCCCGATTGTTTTCGCCACTCC
ATTCTGGAACAAGGTTTGATATGCACAAAAGGAGCCCTCTTCTGAGAGCTCCAAGATTTACTCCAAGTGAGGCTCACTCTAGAATATTTG
AGTCTGTAACCTTGCCTAGTAATCGAACTTCTGCTGGAACATCTTCTTCAGGAGTATCCAATAGAAAAAGGAAAAGAAAAGTGTTTAGTC
CTATTCGATCTGAACCAAGATCTCCTTCTCACTCCATGAGGACAAGAAGTGGAAGGCTTAGTAGTTCTGAGCTCTCACCTCTCACCCCCC
CGTCTTCTGTCTCTTCCTCGTTAAGCATTTCTGTTAGTCCTCTTGCCACTAGTGCCTTAAACCCAACTTTTACTTTTCCTTCTCATTCCC
TGACTCAGTCTGGGGAATCTGCAGAGAAAAATCAGAGACCAAGGAAGCAGACTAGTGCTCCGGCAGAGCCATTTTCATCAAGTAGTCCTA
CTCCTCTCTTCCCTTGGTTTACCCCAGGCTCTCAGACTGAAAGAGGGAGAAATAAAGACAAGGCCCCCGAGGAGCTGTCCAAAGATCGAG
ATGCTGACAAGAGCGTGGAGAAGGACAAGAGTAGAGAGAGAGACCGGGAGAGAGAAAAGGAGAATAAGCGGGAGTCAAGGAAAGAGAAAA
GGAAAAAGGGATCAGAAATTCAGAGTAGTTCTGCTTTGTATCCTGTGGGTAGGGTTTCCAAAGAGAAGGTTGTTGGTGAAGATGTTGCCA
CTTCATCTTCTGCCAAAAAAGCAACAGGGCGGAAGAAGTCTTCATCACATGATTCTGGGACTGATATTACTTCTGTGACTCTTGGGGATA
CAACAGCTGTCAAAACCAAAATACTTATAAAGAAAGGGAGAGGAAATCTGGAAAAAACCAACTTGGACCTCGGCCCAACTGCCCCATCCC
TGGAGAAGGAGAAAACCCTCTGCCTTTCCACTCCTTCATCTAGCACTGTTAAACATTCCACTTCCTCCATAGGCTCCATGTTGGCTCAGG
CAGACAAGCTTCCAATGACTGACAAGAGGGTTGCCAGCCTCCTAAAAAAGGCCAAAGCTCAGCTCTGCAAGATTGAGAAGAGTAAGAGTC
TTAAACAAACCGACCAGCCCAAAGCACAGGGTCAAGAAAGTGACTCATCAGAGACCTCTGTGCGAGGACCCCGGATTAAACATGTCTGCA
GAAGAGCAGCTGTTGCCCTTGGCCGAAAACGAGCTGTGTTTCCTGATGACATGCCCACCCTGAGTGCCTTACCATGGGAAGAACGAGAAA
AGATTTTGTCTTCCATGGGGAATGATGACAAGTCATCAATTGCTGGCTCAGAAGATGCTGAACCTCTTGCTCCACCCATCAAACCAATTA
AACCTGTCACTAGAAACAAGGCACCCCAGGAACCTCCAGTAAAGAAAGGACGTCGATCGAGGCGGTGTGGGCAGTGTCCCGGCTGCCAGG
TGCCTGAGGACTGTGGTGTTTGTACTAATTGCTTAGATAAGCCCAAGTTTGGTGGTCGCAATATAAAGAAGCAGTGCTGCAAGATGAGAA
AATGTCAGAATCTACAATGGATGCCTTCCAAAGCCTACCTGCAGAAGCAAGCTAAAGCTGTGAAAAAGAAAGAGAAAAAGTCTAAGACCA
GTGAAAAGAAAGACAGCAAAGAGAGCAGTGTTGTGAAGAACGTGGTGGACTCTAGTCAGAAACCTACCCCATCAGCAAGAGAGGATCCTG
CCCCAAAGAAAAGCAGTAGTGAGCCTCCTCCACGAAAGCCCGTCGAGGAAAAGAGTGAAGAAGGGAATGTCTCGGCCCCTGGGCCTGAAT
CCAAACAGGCCACCACTCCAGCTTCCAGGAAGTCAAGCAAGCAGGTCTCCCAGCCAGCACTGGTCATCCCGCCTCAGCCACCTACTACAG
GACCGCCAAGAAAAGAAGTTCCCAAAACCACTCCTAGTGAGCCCAAGAAAAAGCAGCCTCCACCACCAGAATCAGGTCCAGAGCAGAGCA
AACAGAAAAAAGTGGCTCCCCGCCCAAGTATCCCTGTAAAACAAAAACCAAAAGAAAAGGAAAAACCACCTCCGGTCAATAAGCAGGAGA
ATGCAGGCACTTTGAACATCCTCAGCACTCTCTCCAATGGCAATAGTTCTAAGCAAAAAATTCCAGCAGATGGAGTCCACAGGATCAGAG
TGGACTTTAAGGAGGATTGTGAAGCAGAAAATGTGTGGGAGATGGGAGGCTTAGGAATCTTGACTTCTGTTCCTATAACACCCAGGGTGG
TTTGCTTTCTCTGTGCCAGTAGTGGGCATGTAGAGGACGCCAACAAGGAGAGCAGCAAGACCTCCAAGCCACACAAGGTGACCAAGGAGC
ACCGGGAGCGGCCCCGCAAAGACTCCGAGAGCAAGAGCTCCTCCAAGGAGCTGGAGCGTGAGCAGGCCAAAAGCTCCAAGGACACCTCGC
GGAAGCTGGGCGAGGGCCGGCTGCCCAAGGAGGAGAAGGCGCCACCGCCCAAGGCTGCCTTCAAGGAACCCAAGATGGCCCTGAAAGAGA
CCAAGCTGGAAAGCACGTCCCCCAAGGGTGGGCCCCCACCCCCACCCCCACCCCCACCCCGGGCTTCCAGCAAGCGGCCGGCCACCGCCG
ACTCGCCAAAGCCCAGCGCCAAGAAGCAGAAGAAGAGCAGCTCGAAGGGGTCCCGGAGTGCTCCAGGCACCTCGCCCCGCACCTCCTCCT
CCTCCTCCTTCTCGGACAAGAAGCCGGCCAAGGACAAGAGCAGCACCAGAGGGGAGAAGGTGAAGGCCGAGAGTGAGCCCCGGGAGGCCA
AAAAGGCCCTGGAGGTGGAGGAGTCCAACTCAGAGGACGAGGCCTCCTTCAAGTCCGAGTCTGCCCAGTCAAGCCCGTCCAACTCCAGCT
CCAGCTCAGACTCCAGCTCAGACTCAGACTTCGAGCCATCCCAGAACCACAGCCAAGGACCCCTGCGCTCCATGGTGGAGGACCTGCAGT
CCGAGGAGTCCGACGAGGACGACTCTTCGTCAGGCGAGGAGGCTGCCGGCAAGACCAACCCGGGGAGGGACTCCAGGTTGAGCTTCAGCG
ACAGCGAGAGTGACAACAGCGCCGACTCCTCCCTGCCCAGCCGTGAGCCCCCACCCCCCCAGAAGCCACCCCCGCCCAACAGCAAGGTGT
CAGGCCGGAGGAGCCCCGAGTCCTGCAGCAAGCCTGAGAAGATCCTCAAGAAGGGCACCTACGACAAGGCCTACACGGATGAGCTGGTGG
AGCTACACCGGAGGCTGATGGCGCTGCGGGAGCGCAACGTGCTGCAGCAGATTGTGAATCTGATCGAGGAGACTGGCCACTTCAATGTCA
CCAACACCACCTTCGACTTCGACCTCTTCTCCCTGGACGAGACCACCGTGCGCAAACTGCAGAGCTGCCTGGAGGCCGTGGCCACATGAC

>In-frame_ENST00000534358_ENST00000252674_DQ224342_KMT2A_chr11_118355691_+_MLLT1_chr19_6222697_length(amino acids)=1821AA_start in transcript=23_stop in transcript=5488
MAHSCRWRFPARPGTTGGGGGGGRRGLGGAPRQRVPALLLPPGPPVGGGGPGAPPSPPAVAAAAAAAGSSGAGVPGGAAAASAASSSSAS
SSSSSSSSASSGPALLRVGPGFDAALQVSAAIGTNLRRFRAVFGESGGGGGSGEDEQFLGFGSDEEVRVRSPTRSPSVKTSPRKPRGRPR
SGSDRNSAILSDPSVFSPLNKSETKSGDKIKKKDSKSIEKKRGRPPTFPGVKIKITHGKDISELPKGNKEDSLKKIKRTPSATFQQATKI
KKLRAGKLSPLKSKFKTGKLQIGRKGVQIVRRRGRPPSTERIKTPSGLLINSELEKPQKVRKDKEGTPPLTKEDKTVVRQSPRRIKPVRI
IPSSKRTDATIAKQLLQRAKKGAQKKIEKEAAQLQGRKVKTQVKNIRQFIMPVVSAISSRIIKTPRRFIEDEDYDPPIKIARLESTPNSR
FSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGS
RTTKKLSTLQSAPQQQTSSSPPPPLLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQ
YFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSN
RTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESA
EKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQ
SSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKILIKKGRGNLEKTNLDLGPTAPSLEKEKTLC
LSTPSSSTVKHSTSSIGSMLAQADKLPMTDKRVASLLKKAKAQLCKIEKSKSLKQTDQPKAQGQESDSSETSVRGPRIKHVCRRAAVALG
RKRAVFPDDMPTLSALPWEEREKILSSMGNDDKSSIAGSEDAEPLAPPIKPIKPVTRNKAPQEPPVKKGRRSRRCGQCPGCQVPEDCGVC
TNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKSSSE
PPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPR
PSIPVKQKPKEKEKPPPVNKQENAGTLNILSTLSNGNSSKQKIPADGVHRIRVDFKEDCEAENVWEMGGLGILTSVPITPRVVCFLCASS
GHVEDANKESSKTSKPHKVTKEHRERPRKDSESKSSSKELEREQAKSSKDTSRKLGEGRLPKEEKAPPPKAAFKEPKMALKETKLESTSP
KGGPPPPPPPPPRASSKRPATADSPKPSAKKQKKSSSKGSRSAPGTSPRTSSSSSFSDKKPAKDKSSTRGEKVKAESEPREAKKALEVEE
SNSEDEASFKSESAQSSPSNSSSSSDSSSDSDFEPSQNHSQGPLRSMVEDLQSEESDEDDSSSGEEAAGKTNPGRDSRLSFSDSESDNSA
DSSLPSREPPPPQKPPPPNSKVSGRRSPESCSKPEKILKKGTYDKAYTDELVELHRRLMALRERNVLQQIVNLIEETGHFNVTNTTFDFD

--------------------------------------------------------------
>In-frame_ENST00000389506_ENST00000252674_DQ224342_KMT2A_chr11_118355691_+_MLLT1_chr19_6222697_length(transcript)=5553nt_BP=4332nt
ATGGCGCACAGCTGTCGGTGGCGCTTCCCCGCCCGACCCGGGACCACCGGGGGCGGCGGCGGCGGGGGGCGCCGGGGCCTAGGGGGCGCC
CCGCGGCAACGCGTCCCGGCCCTGCTGCTTCCCCCCGGGCCCCCGGTCGGCGGTGGCGGCCCCGGGGCGCCCCCCTCCCCCCCGGCTGTG
GCGGCCGCGGCGGCGGCGGCGGGAAGCAGCGGGGCTGGGGTTCCAGGGGGAGCGGCCGCCGCCTCAGCAGCCTCCTCGTCGTCCGCCTCG
TCTTCGTCTTCGTCATCGTCCTCAGCCTCTTCAGGGCCGGCCCTGCTCCGGGTGGGCCCGGGCTTCGACGCGGCGCTGCAGGTCTCGGCC
GCCATCGGCACCAACCTGCGCCGGTTCCGGGCCGTGTTTGGGGAGAGCGGCGGGGGAGGCGGCAGCGGAGAGGATGAGCAATTCTTAGGT
TTTGGCTCAGATGAAGAAGTCAGAGTGCGAAGTCCCACAAGGTCTCCTTCAGTTAAAACTAGTCCTCGAAAACCTCGTGGGAGACCTAGA
AGTGGCTCTGACCGAAATTCAGCTATCCTCTCAGATCCATCTGTGTTTTCCCCTCTAAATAAATCAGAGACCAAATCTGGAGATAAGATC
AAGAAGAAAGATTCTAAAAGTATAGAAAAGAAGAGAGGAAGACCTCCCACCTTCCCTGGAGTAAAAATCAAAATAACACATGGAAAGGAC
ATTTCAGAGTTACCAAAGGGAAACAAAGAAGATAGCCTGAAAAAAATTAAAAGGACACCTTCTGCTACGTTTCAGCAAGCCACAAAGATT
AAAAAATTAAGAGCAGGTAAACTCTCTCCTCTCAAGTCTAAGTTTAAGACAGGGAAGCTTCAAATAGGAAGGAAGGGGGTACAAATTGTA
CGACGGAGAGGAAGGCCTCCATCAACAGAAAGGATAAAGACCCCTTCGGGTCTCCTCATTAATTCTGAACTGGAAAAGCCCCAGAAAGTC
CGGAAAGACAAGGAAGGAACACCTCCACTTACAAAAGAAGATAAGACAGTTGTCAGACAAAGCCCTCGAAGGATTAAGCCAGTTAGGATT
ATTCCTTCTTCAAAAAGGACAGATGCAACCATTGCTAAGCAACTCTTACAGAGGGCAAAAAAGGGGGCTCAAAAGAAAATTGAAAAAGAA
GCAGCTCAGCTGCAGGGAAGAAAGGTGAAGACACAGGTCAAAAATATTCGACAGTTCATCATGCCTGTTGTCAGTGCTATCTCCTCGCGG
ATCATTAAGACCCCTCGGCGGTTTATAGAGGATGAGGATTATGACCCTCCAATTAAAATTGCCCGATTAGAGTCTACACCGAATAGTAGA
TTCAGTGCCCCGTCCTGTGGATCTTCTGAAAAATCAAGTGCAGCTTCTCAGCACTCCTCTCAAATGTCTTCAGACTCCTCTCGATCTAGT
AGCCCCAGTGTTGATACCTCCACAGACTCTCAGGCTTCTGAGGAGATTCAGGTACTTCCTGAGGAGCGGAGCGATACCCCTGAAGTTCAT
CCTCCACTGCCCATTTCCCAGTCCCCAGAAAATGAGAGTAATGATAGGAGAAGCAGAAGGTATTCAGTGTCGGAGAGAAGTTTTGGATCT
AGAACGACGAAAAAATTATCAACTCTACAAAGTGCCCCCCAGCAGCAGACCTCCTCGTCTCCACCTCCACCTCTGCTGACTCCACCGCCA
CCACTGCAGCCAGCCTCCAGTATCTCTGACCACACACCTTGGCTTATGCCTCCAACAATCCCCTTAGCATCACCATTTTTGCCTGCTTCC
ACTGCTCCTATGCAAGGGAAGCGAAAATCTATTTTGCGAGAACCGACATTTAGGTGGACTTCTTTAAAGCATTCTAGGTCAGAGCCACAA
TACTTTTCCTCAGCAAAGTATGCCAAAGAAGGTCTTATTCGCAAACCAATATTTGATAATTTCCGACCCCCTCCACTAACTCCCGAGGAC
GTTGGCTTTGCATCTGGTTTTTCTGCATCTGGTACCGCTGCTTCAGCCCGATTGTTTTCGCCACTCCATTCTGGAACAAGGTTTGATATG
CACAAAAGGAGCCCTCTTCTGAGAGCTCCAAGATTTACTCCAAGTGAGGCTCACTCTAGAATATTTGAGTCTGTAACCTTGCCTAGTAAT
CGAACTTCTGCTGGAACATCTTCTTCAGGAGTATCCAATAGAAAAAGGAAAAGAAAAGTGTTTAGTCCTATTCGATCTGAACCAAGATCT
CCTTCTCACTCCATGAGGACAAGAAGTGGAAGGCTTAGTAGTTCTGAGCTCTCACCTCTCACCCCCCCGTCTTCTGTCTCTTCCTCGTTA
AGCATTTCTGTTAGTCCTCTTGCCACTAGTGCCTTAAACCCAACTTTTACTTTTCCTTCTCATTCCCTGACTCAGTCTGGGGAATCTGCA
GAGAAAAATCAGAGACCAAGGAAGCAGACTAGTGCTCCGGCAGAGCCATTTTCATCAAGTAGTCCTACTCCTCTCTTCCCTTGGTTTACC
CCAGGCTCTCAGACTGAAAGAGGGAGAAATAAAGACAAGGCCCCCGAGGAGCTGTCCAAAGATCGAGATGCTGACAAGAGCGTGGAGAAG
GACAAGAGTAGAGAGAGAGACCGGGAGAGAGAAAAGGAGAATAAGCGGGAGTCAAGGAAAGAGAAAAGGAAAAAGGGATCAGAAATTCAG
AGTAGTTCTGCTTTGTATCCTGTGGGTAGGGTTTCCAAAGAGAAGGTTGTTGGTGAAGATGTTGCCACTTCATCTTCTGCCAAAAAAGCA
ACAGGGCGGAAGAAGTCTTCATCACATGATTCTGGGACTGATATTACTTCTGTGACTCTTGGGGATACAACAGCTGTCAAAACCAAAATA
CTTATAAAGAAAGGGAGAGGAAATCTGGAAAAAACCAACTTGGACCTCGGCCCAACTGCCCCATCCCTGGAGAAGGAGAAAACCCTCTGC
CTTTCCACTCCTTCATCTAGCACTGTTAAACATTCCACTTCCTCCATAGGCTCCATGTTGGCTCAGGCAGACAAGCTTCCAATGACTGAC
AAGAGGGTTGCCAGCCTCCTAAAAAAGGCCAAAGCTCAGCTCTGCAAGATTGAGAAGAGTAAGAGTCTTAAACAAACCGACCAGCCCAAA
GCACAGGGTCAAGAAAGTGACTCATCAGAGACCTCTGTGCGAGGACCCCGGATTAAACATGTCTGCAGAAGAGCAGCTGTTGCCCTTGGC
CGAAAACGAGCTGTGTTTCCTGATGACATGCCCACCCTGAGTGCCTTACCATGGGAAGAACGAGAAAAGATTTTGTCTTCCATGGGGAAT
GATGACAAGTCATCAATTGCTGGCTCAGAAGATGCTGAACCTCTTGCTCCACCCATCAAACCAATTAAACCTGTCACTAGAAACAAGGCA
CCCCAGGAACCTCCAGTAAAGAAAGGACGTCGATCGAGGCGGTGTGGGCAGTGTCCCGGCTGCCAGGTGCCTGAGGACTGTGGTGTTTGT
ACTAATTGCTTAGATAAGCCCAAGTTTGGTGGTCGCAATATAAAGAAGCAGTGCTGCAAGATGAGAAAATGTCAGAATCTACAATGGATG
CCTTCCAAAGCCTACCTGCAGAAGCAAGCTAAAGCTGTGAAAAAGAAAGAGAAAAAGTCTAAGACCAGTGAAAAGAAAGACAGCAAAGAG
AGCAGTGTTGTGAAGAACGTGGTGGACTCTAGTCAGAAACCTACCCCATCAGCAAGAGAGGATCCTGCCCCAAAGAAAAGCAGTAGTGAG
CCTCCTCCACGAAAGCCCGTCGAGGAAAAGAGTGAAGAAGGGAATGTCTCGGCCCCTGGGCCTGAATCCAAACAGGCCACCACTCCAGCT
TCCAGGAAGTCAAGCAAGCAGGTCTCCCAGCCAGCACTGGTCATCCCGCCTCAGCCACCTACTACAGGACCGCCAAGAAAAGAAGTTCCC
AAAACCACTCCTAGTGAGCCCAAGAAAAAGCAGCCTCCACCACCAGAATCAGGTCCAGAGCAGAGCAAACAGAAAAAAGTGGCTCCCCGC
CCAAGTATCCCTGTAAAACAAAAACCAAAAGAAAAGGAAAAACCACCTCCGGTCAATAAGCAGGAGAATGCAGGCACTTTGAACATCCTC
AGCACTCTCTCCAATGGCAATAGTTCTAAGCAAAAAATTCCAGCAGATGGAGTCCACAGGATCAGAGTGGACTTTAAGGAGGATTGTGAA
GCAGAAAATGTGTGGGAGATGGGAGGCTTAGGAATCTTGACTTCTGTTCCTATAACACCCAGGGTGGTTTGCTTTCTCTGTGCCAGTAGT
GGGCATGTAGAGGACGCCAACAAGGAGAGCAGCAAGACCTCCAAGCCACACAAGGTGACCAAGGAGCACCGGGAGCGGCCCCGCAAAGAC
TCCGAGAGCAAGAGCTCCTCCAAGGAGCTGGAGCGTGAGCAGGCCAAAAGCTCCAAGGACACCTCGCGGAAGCTGGGCGAGGGCCGGCTG
CCCAAGGAGGAGAAGGCGCCACCGCCCAAGGCTGCCTTCAAGGAACCCAAGATGGCCCTGAAAGAGACCAAGCTGGAAAGCACGTCCCCC
AAGGGTGGGCCCCCACCCCCACCCCCACCCCCACCCCGGGCTTCCAGCAAGCGGCCGGCCACCGCCGACTCGCCAAAGCCCAGCGCCAAG
AAGCAGAAGAAGAGCAGCTCGAAGGGGTCCCGGAGTGCTCCAGGCACCTCGCCCCGCACCTCCTCCTCCTCCTCCTTCTCGGACAAGAAG
CCGGCCAAGGACAAGAGCAGCACCAGAGGGGAGAAGGTGAAGGCCGAGAGTGAGCCCCGGGAGGCCAAAAAGGCCCTGGAGGTGGAGGAG
TCCAACTCAGAGGACGAGGCCTCCTTCAAGTCCGAGTCTGCCCAGTCAAGCCCGTCCAACTCCAGCTCCAGCTCAGACTCCAGCTCAGAC
TCAGACTTCGAGCCATCCCAGAACCACAGCCAAGGACCCCTGCGCTCCATGGTGGAGGACCTGCAGTCCGAGGAGTCCGACGAGGACGAC
TCTTCGTCAGGCGAGGAGGCTGCCGGCAAGACCAACCCGGGGAGGGACTCCAGGTTGAGCTTCAGCGACAGCGAGAGTGACAACAGCGCC
GACTCCTCCCTGCCCAGCCGTGAGCCCCCACCCCCCCAGAAGCCACCCCCGCCCAACAGCAAGGTGTCAGGCCGGAGGAGCCCCGAGTCC
TGCAGCAAGCCTGAGAAGATCCTCAAGAAGGGCACCTACGACAAGGCCTACACGGATGAGCTGGTGGAGCTACACCGGAGGCTGATGGCG
CTGCGGGAGCGCAACGTGCTGCAGCAGATTGTGAATCTGATCGAGGAGACTGGCCACTTCAATGTCACCAACACCACCTTCGACTTCGAC
CTCTTCTCCCTGGACGAGACCACCGTGCGCAAACTGCAGAGCTGCCTGGAGGCCGTGGCCACATGACCCTGGGCCGCGTGCCGGGCCCCC

>In-frame_ENST00000389506_ENST00000252674_DQ224342_KMT2A_chr11_118355691_+_MLLT1_chr19_6222697_length(amino acids)=1821AA_start in transcript=0_stop in transcript=5465
MAHSCRWRFPARPGTTGGGGGGGRRGLGGAPRQRVPALLLPPGPPVGGGGPGAPPSPPAVAAAAAAAGSSGAGVPGGAAAASAASSSSAS
SSSSSSSSASSGPALLRVGPGFDAALQVSAAIGTNLRRFRAVFGESGGGGGSGEDEQFLGFGSDEEVRVRSPTRSPSVKTSPRKPRGRPR
SGSDRNSAILSDPSVFSPLNKSETKSGDKIKKKDSKSIEKKRGRPPTFPGVKIKITHGKDISELPKGNKEDSLKKIKRTPSATFQQATKI
KKLRAGKLSPLKSKFKTGKLQIGRKGVQIVRRRGRPPSTERIKTPSGLLINSELEKPQKVRKDKEGTPPLTKEDKTVVRQSPRRIKPVRI
IPSSKRTDATIAKQLLQRAKKGAQKKIEKEAAQLQGRKVKTQVKNIRQFIMPVVSAISSRIIKTPRRFIEDEDYDPPIKIARLESTPNSR
FSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGS
RTTKKLSTLQSAPQQQTSSSPPPPLLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQ
YFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSN
RTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESA
EKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQ
SSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKILIKKGRGNLEKTNLDLGPTAPSLEKEKTLC
LSTPSSSTVKHSTSSIGSMLAQADKLPMTDKRVASLLKKAKAQLCKIEKSKSLKQTDQPKAQGQESDSSETSVRGPRIKHVCRRAAVALG
RKRAVFPDDMPTLSALPWEEREKILSSMGNDDKSSIAGSEDAEPLAPPIKPIKPVTRNKAPQEPPVKKGRRSRRCGQCPGCQVPEDCGVC
TNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKSSSE
PPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPR
PSIPVKQKPKEKEKPPPVNKQENAGTLNILSTLSNGNSSKQKIPADGVHRIRVDFKEDCEAENVWEMGGLGILTSVPITPRVVCFLCASS
GHVEDANKESSKTSKPHKVTKEHRERPRKDSESKSSSKELEREQAKSSKDTSRKLGEGRLPKEEKAPPPKAAFKEPKMALKETKLESTSP
KGGPPPPPPPPPRASSKRPATADSPKPSAKKQKKSSSKGSRSAPGTSPRTSSSSSFSDKKPAKDKSSTRGEKVKAESEPREAKKALEVEE
SNSEDEASFKSESAQSSPSNSSSSSDSSSDSDFEPSQNHSQGPLRSMVEDLQSEESDEDDSSSGEEAAGKTNPGRDSRLSFSDSESDNSA
DSSLPSREPPPPQKPPPPNSKVSGRRSPESCSKPEKILKKGTYDKAYTDELVELHRRLMALRERNVLQQIVNLIEETGHFNVTNTTFDFD

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Fusion Gene PPI Analysis for KMT2A-MLLT1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneKMT2Achr11:118355030chr19:6222697ENST00000354520+9351584_16001406.03932.0histone H3K4me3
HgeneKMT2Achr11:118355030chr19:6222697ENST00000389506+9361584_16001406.03970.0histone H3K4me3
HgeneKMT2Achr11:118355030chr19:6222697ENST00000534358+9361584_16001406.03973.0histone H3K4me3
HgeneKMT2Achr11:118355030chr19:6230726ENST00000354520+9351584_16001406.03932.0histone H3K4me3
HgeneKMT2Achr11:118355030chr19:6230726ENST00000389506+9361584_16001406.03970.0histone H3K4me3
HgeneKMT2Achr11:118355030chr19:6230726ENST00000534358+9361584_16001406.03973.0histone H3K4me3
HgeneKMT2Achr11:118355690chr19:6270772ENST00000354520+1351584_16000.03932.0histone H3K4me3
HgeneKMT2Achr11:118355690chr19:6270772ENST00000389506+10361584_16001444.03970.0histone H3K4me3
HgeneKMT2Achr11:118355690chr19:6270772ENST00000534358+10361584_16001444.03973.0histone H3K4me3
HgeneKMT2Achr11:118355691chr19:6222697ENST00000354520+1351584_16000.03932.0histone H3K4me3
HgeneKMT2Achr11:118355691chr19:6222697ENST00000389506+10361584_16001444.03970.0histone H3K4me3
HgeneKMT2Achr11:118355691chr19:6222697ENST00000534358+10361584_16001444.03973.0histone H3K4me3


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for KMT2A-MLLT1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for KMT2A-MLLT1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneKMT2AC2826025Mixed phenotype acute leukemia3ORPHANET
HgeneKMT2AC0023418leukemia2CTD_human
HgeneKMT2AC0023452Childhood Acute Lymphoblastic Leukemia2CTD_human
HgeneKMT2AC0023453L2 Acute Lymphoblastic Leukemia2CTD_human
HgeneKMT2AC0023466Leukemia, Monocytic, Chronic2CTD_human
HgeneKMT2AC0023467Leukemia, Myelocytic, Acute2CTD_human
HgeneKMT2AC0023470Myeloid Leukemia2CTD_human
HgeneKMT2AC0026998Acute Myeloid Leukemia, M12CTD_human
HgeneKMT2AC1854630Growth Deficiency and Mental Retardation with Facial Dysmorphism2CTD_human;GENOMICS_ENGLAND;ORPHANET
HgeneKMT2AC1879321Acute Myeloid Leukemia (AML-M2)2CTD_human
HgeneKMT2AC1961102Precursor Cell Lymphoblastic Leukemia Lymphoma2CTD_human
HgeneKMT2AC0001418Adenocarcinoma1CTD_human
HgeneKMT2AC0004403Autosome Abnormalities1CTD_human
HgeneKMT2AC0005684Malignant neoplasm of urinary bladder1CTD_human
HgeneKMT2AC0005695Bladder Neoplasm1CTD_human
HgeneKMT2AC0007138Carcinoma, Transitional Cell1CTD_human
HgeneKMT2AC0008625Chromosome Aberrations1CTD_human
HgeneKMT2AC0023448Lymphoid leukemia1CTD_human
HgeneKMT2AC0023465Acute monocytic leukemia1CTD_human
HgeneKMT2AC0023479Acute myelomonocytic leukemia1CTD_human
HgeneKMT2AC0024623Malignant neoplasm of stomach1CTD_human
HgeneKMT2AC0033578Prostatic Neoplasms1CTD_human
HgeneKMT2AC0036341Schizophrenia1PSYGENET
HgeneKMT2AC0038356Stomach Neoplasms1CTD_human
HgeneKMT2AC0149925Small cell carcinoma of lung1CTD_human
HgeneKMT2AC0205641Adenocarcinoma, Basal Cell1CTD_human
HgeneKMT2AC0205642Adenocarcinoma, Oxyphilic1CTD_human
HgeneKMT2AC0205643Carcinoma, Cribriform1CTD_human
HgeneKMT2AC0205644Carcinoma, Granular Cell1CTD_human
HgeneKMT2AC0205645Adenocarcinoma, Tubular1CTD_human
HgeneKMT2AC0270972Cornelia De Lange Syndrome1ORPHANET
HgeneKMT2AC0280141Acute Undifferentiated Leukemia1ORPHANET
HgeneKMT2AC0376358Malignant neoplasm of prostate1CTD_human
HgeneKMT2AC0856823Undifferentiated type acute leukemia1ORPHANET
HgeneKMT2AC1535926Neurodevelopmental Disorders1CTD_human
HgeneKMT2AC1708349Hereditary Diffuse Gastric Cancer1CTD_human
HgeneKMT2AC2239176Liver carcinoma1CTD_human
HgeneKMT2AC2930974Acute erythroleukemia1CTD_human
HgeneKMT2AC2930975Acute erythroleukemia - M6a subtype1CTD_human
HgeneKMT2AC2930976Acute myeloid leukemia FAB-M61CTD_human
HgeneKMT2AC2930977Acute erythroleukemia - M6b subtype1CTD_human
TgeneMLLT1C0027708Nephroblastoma1CTD_human
TgeneMLLT1C2930471Bilateral Wilms Tumor1CTD_human