FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:LAMA3-C18orf8 (FusionGDB2 ID:43624)

Fusion Gene Summary for LAMA3-C18orf8

check button Fusion gene summary
Fusion gene informationFusion gene name: LAMA3-C18orf8
Fusion gene ID: 43624
HgeneTgene
Gene symbol

LAMA3

C18orf8

Gene ID

3910

29919

Gene namelaminin subunit alpha 4regulator of MON1-CCZ1
SynonymsCMD1JJ|LAMA3|LAMA4*-1C18orf8|HsT2591|MIC1|Mic-1|WDR98
Cytomap

6q21

18q11.2

Type of geneprotein-codingprotein-coding
Descriptionlaminin subunit alpha-4laminin alpha 4 chainlaminin, alpha 4regulator of MON1-CCZ1 complexWD repeat domain 98WD repeat-containing protein 98colon cancer-associated protein Mic1macrophage inhibitory cytokine 1uncharacterized protein C18orf8
Modification date2020031320200313
UniProtAcc

Q16787

.
Ensembl transtripts involved in fusion geneENST00000313654, ENST00000399516, 
ENST00000269217, ENST00000587184, 
ENST00000588770, 		ENST00000269221, 
ENST00000590868, ENST00000591367, 
Fusion gene scores* DoF score28 X 24 X 10=67202 X 3 X 3=18
# samples 333
** MAII scorelog2(33/6720*10)=-4.34792330342031
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(3/18*10)=0.736965594166206
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: LAMA3 [Title/Abstract] AND C18orf8 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointLAMA3(21294036)-C18orf8(21095820), # samples:2
C18orf8(21085961)-LAMA3(21321917), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across LAMA3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across C18orf8 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUADTCGA-55-A493-01ALAMA3chr18

21294036

+C18orf8chr18

21109143

+
ChimerDB4LUSCTCGA-43-8115-01ALAMA3chr18

21294036

+C18orf8chr18

21095820

+
ChimerDB4LUSCTCGA-43-8115-01ALAMA3chr18

21294036

-C18orf8chr18

21095820

+


Top

Fusion Gene ORF analysis for LAMA3-C18orf8

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000313654ENST00000269221LAMA3chr18

21294036

+C18orf8chr18

21109143

+
In-frameENST00000313654ENST00000590868LAMA3chr18

21294036

+C18orf8chr18

21109143

+
5CDS-intronENST00000313654ENST00000591367LAMA3chr18

21294036

+C18orf8chr18

21109143

+
In-frameENST00000399516ENST00000269221LAMA3chr18

21294036

+C18orf8chr18

21109143

+
In-frameENST00000399516ENST00000590868LAMA3chr18

21294036

+C18orf8chr18

21109143

+
5CDS-intronENST00000399516ENST00000591367LAMA3chr18

21294036

+C18orf8chr18

21109143

+
intron-3CDSENST00000269217ENST00000269221LAMA3chr18

21294036

+C18orf8chr18

21109143

+
intron-3CDSENST00000269217ENST00000590868LAMA3chr18

21294036

+C18orf8chr18

21109143

+
intron-intronENST00000269217ENST00000591367LAMA3chr18

21294036

+C18orf8chr18

21109143

+
intron-3CDSENST00000587184ENST00000269221LAMA3chr18

21294036

+C18orf8chr18

21109143

+
intron-3CDSENST00000587184ENST00000590868LAMA3chr18

21294036

+C18orf8chr18

21109143

+
intron-intronENST00000587184ENST00000591367LAMA3chr18

21294036

+C18orf8chr18

21109143

+
intron-3CDSENST00000588770ENST00000269221LAMA3chr18

21294036

+C18orf8chr18

21109143

+
intron-3CDSENST00000588770ENST00000590868LAMA3chr18

21294036

+C18orf8chr18

21109143

+
intron-intronENST00000588770ENST00000591367LAMA3chr18

21294036

+C18orf8chr18

21109143

+
In-frameENST00000313654ENST00000269221LAMA3chr18

21294036

+C18orf8chr18

21095820

+
In-frameENST00000313654ENST00000590868LAMA3chr18

21294036

+C18orf8chr18

21095820

+
5CDS-intronENST00000313654ENST00000591367LAMA3chr18

21294036

+C18orf8chr18

21095820

+
In-frameENST00000399516ENST00000269221LAMA3chr18

21294036

+C18orf8chr18

21095820

+
In-frameENST00000399516ENST00000590868LAMA3chr18

21294036

+C18orf8chr18

21095820

+
5CDS-intronENST00000399516ENST00000591367LAMA3chr18

21294036

+C18orf8chr18

21095820

+
intron-3CDSENST00000269217ENST00000269221LAMA3chr18

21294036

+C18orf8chr18

21095820

+
intron-3CDSENST00000269217ENST00000590868LAMA3chr18

21294036

+C18orf8chr18

21095820

+
intron-intronENST00000269217ENST00000591367LAMA3chr18

21294036

+C18orf8chr18

21095820

+
intron-3CDSENST00000587184ENST00000269221LAMA3chr18

21294036

+C18orf8chr18

21095820

+
intron-3CDSENST00000587184ENST00000590868LAMA3chr18

21294036

+C18orf8chr18

21095820

+
intron-intronENST00000587184ENST00000591367LAMA3chr18

21294036

+C18orf8chr18

21095820

+
intron-3CDSENST00000588770ENST00000269221LAMA3chr18

21294036

+C18orf8chr18

21095820

+
intron-3CDSENST00000588770ENST00000590868LAMA3chr18

21294036

+C18orf8chr18

21095820

+
intron-intronENST00000588770ENST00000591367LAMA3chr18

21294036

+C18orf8chr18

21095820

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000313654LAMA3chr1821294036+ENST00000269221C18orf8chr1821109143+14446882411365374
ENST00000313654LAMA3chr1821294036+ENST00000590868C18orf8chr1821109143+14386882411365374
ENST00000399516LAMA3chr1821294036+ENST00000269221C18orf8chr1821109143+120344701124374
ENST00000399516LAMA3chr1821294036+ENST00000590868C18orf8chr1821109143+119744701124374
ENST00000313654LAMA3chr1821294036+ENST00000269221C18orf8chr1821095820+23326882412253670
ENST00000313654LAMA3chr1821294036+ENST00000590868C18orf8chr1821095820+23266882412253670
ENST00000399516LAMA3chr1821294036+ENST00000269221C18orf8chr1821095820+209144702012670
ENST00000399516LAMA3chr1821294036+ENST00000590868C18orf8chr1821095820+208544702012670

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000313654ENST00000269221LAMA3chr1821294036+C18orf8chr1821109143+0.0062768850.9937231
ENST00000313654ENST00000590868LAMA3chr1821294036+C18orf8chr1821109143+0.0066746230.99332535
ENST00000399516ENST00000269221LAMA3chr1821294036+C18orf8chr1821109143+0.0020823390.9979177
ENST00000399516ENST00000590868LAMA3chr1821294036+C18orf8chr1821109143+0.0022394330.99776053
ENST00000313654ENST00000269221LAMA3chr1821294036+C18orf8chr1821095820+0.0051588440.99484116
ENST00000313654ENST00000590868LAMA3chr1821294036+C18orf8chr1821095820+0.0052698080.9947301
ENST00000399516ENST00000269221LAMA3chr1821294036+C18orf8chr1821095820+0.0033851180.9966149
ENST00000399516ENST00000590868LAMA3chr1821294036+C18orf8chr1821095820+0.0034875120.9965125

Top

Fusion Genomic Features for LAMA3-C18orf8


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
LAMA3chr1821294036+C18orf8chr1821109142+4.71E-091
LAMA3chr1821294036+C18orf8chr1821095819+6.46E-091
LAMA3chr1821294036+C18orf8chr1821109142+4.71E-091
LAMA3chr1821294036+C18orf8chr1821095819+6.46E-091

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

Top

Fusion Protein Features for LAMA3-C18orf8


check button Go to

FGviewer for the breakpoints of chr18:21294036-chr18:21109143

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
LAMA3

Q16787

.
FUNCTION: Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.; FUNCTION: Laminin-5 is thought to be involved in (1) cell adhesion via integrin alpha-3/beta-1 in focal adhesion and integrin alpha-6/beta-4 in hemidesmosomes, (2) signal transduction via tyrosine phosphorylation of pp125-FAK and p80, (3) differentiation of keratinocytes.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneC18orf8chr18:21294036chr18:21095820ENST00000269221420471_637136.0658.0DomainNote=Mic1
TgeneC18orf8chr18:21294036chr18:21109143ENST000002692211320471_637432.0658.0DomainNote=Mic1

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneLAMA3chr18:21294036chr18:21095820ENST00000313654+2751852_1941149.03334.0Coiled coilOntology_term=ECO:0000255
HgeneLAMA3chr18:21294036chr18:21095820ENST00000313654+2751987_2169149.03334.0Coiled coilOntology_term=ECO:0000255
HgeneLAMA3chr18:21294036chr18:21095820ENST00000313654+2752322_2388149.03334.0Coiled coilOntology_term=ECO:0000255
HgeneLAMA3chr18:21294036chr18:21095820ENST00000399516+2741852_1941149.03278.0Coiled coilOntology_term=ECO:0000255
HgeneLAMA3chr18:21294036chr18:21095820ENST00000399516+2741987_2169149.03278.0Coiled coilOntology_term=ECO:0000255
HgeneLAMA3chr18:21294036chr18:21095820ENST00000399516+2742322_2388149.03278.0Coiled coilOntology_term=ECO:0000255
HgeneLAMA3chr18:21294036chr18:21095820ENST00000587184+1371852_19410.01669.0Coiled coilOntology_term=ECO:0000255
HgeneLAMA3chr18:21294036chr18:21095820ENST00000587184+1371987_21690.01669.0Coiled coilOntology_term=ECO:0000255
HgeneLAMA3chr18:21294036chr18:21095820ENST00000587184+1372322_23880.01669.0Coiled coilOntology_term=ECO:0000255
HgeneLAMA3chr18:21294036chr18:21109143ENST00000313654+2751852_1941149.03334.0Coiled coilOntology_term=ECO:0000255
HgeneLAMA3chr18:21294036chr18:21109143ENST00000313654+2751987_2169149.03334.0Coiled coilOntology_term=ECO:0000255
HgeneLAMA3chr18:21294036chr18:21109143ENST00000313654+2752322_2388149.03334.0Coiled coilOntology_term=ECO:0000255
HgeneLAMA3chr18:21294036chr18:21109143ENST00000399516+2741852_1941149.03278.0Coiled coilOntology_term=ECO:0000255
HgeneLAMA3chr18:21294036chr18:21109143ENST00000399516+2741987_2169149.03278.0Coiled coilOntology_term=ECO:0000255
HgeneLAMA3chr18:21294036chr18:21109143ENST00000399516+2742322_2388149.03278.0Coiled coilOntology_term=ECO:0000255
HgeneLAMA3chr18:21294036chr18:21109143ENST00000587184+1371852_19410.01669.0Coiled coilOntology_term=ECO:0000255
HgeneLAMA3chr18:21294036chr18:21109143ENST00000587184+1371987_21690.01669.0Coiled coilOntology_term=ECO:0000255
HgeneLAMA3chr18:21294036chr18:21109143ENST00000587184+1372322_23880.01669.0Coiled coilOntology_term=ECO:0000255
HgeneLAMA3chr18:21294036chr18:21095820ENST00000313654+2751266_1311149.03334.0DomainLaminin EGF-like 9
HgeneLAMA3chr18:21294036chr18:21095820ENST00000313654+2751312_1355149.03334.0DomainLaminin EGF-like 10
HgeneLAMA3chr18:21294036chr18:21095820ENST00000313654+2751356_1404149.03334.0DomainLaminin EGF-like 11
HgeneLAMA3chr18:21294036chr18:21095820ENST00000313654+2751405_1455149.03334.0DomainLaminin EGF-like 12
HgeneLAMA3chr18:21294036chr18:21095820ENST00000313654+2751476_1653149.03334.0DomainLaminin IV type A
HgeneLAMA3chr18:21294036chr18:21095820ENST00000313654+2751687_1733149.03334.0DomainLaminin EGF-like 13
HgeneLAMA3chr18:21294036chr18:21095820ENST00000313654+2751734_1786149.03334.0DomainLaminin EGF-like 14
HgeneLAMA3chr18:21294036chr18:21095820ENST00000313654+2751787_1821149.03334.0DomainLaminin EGF-like 15%3B truncated
HgeneLAMA3chr18:21294036chr18:21095820ENST00000313654+2752390_2591149.03334.0DomainLaminin G-like 1
HgeneLAMA3chr18:21294036chr18:21095820ENST00000313654+2752598_2760149.03334.0DomainLaminin G-like 2
HgeneLAMA3chr18:21294036chr18:21095820ENST00000313654+2752767_2927149.03334.0DomainLaminin G-like 3
HgeneLAMA3chr18:21294036chr18:21095820ENST00000313654+2752986_3150149.03334.0DomainLaminin G-like 4
HgeneLAMA3chr18:21294036chr18:21095820ENST00000313654+275299_355149.03334.0DomainLaminin EGF-like 1
HgeneLAMA3chr18:21294036chr18:21095820ENST00000313654+2753157_3330149.03334.0DomainLaminin G-like 5
HgeneLAMA3chr18:21294036chr18:21095820ENST00000313654+275356_425149.03334.0DomainLaminin EGF-like 2
HgeneLAMA3chr18:21294036chr18:21095820ENST00000313654+275426_469149.03334.0DomainLaminin EGF-like 3
HgeneLAMA3chr18:21294036chr18:21095820ENST00000313654+27543_298149.03334.0DomainLaminin N-terminal
HgeneLAMA3chr18:21294036chr18:21095820ENST00000313654+275491_535149.03334.0DomainLaminin EGF-like 4
HgeneLAMA3chr18:21294036chr18:21095820ENST00000313654+275536_588149.03334.0DomainLaminin EGF-like 5
HgeneLAMA3chr18:21294036chr18:21095820ENST00000313654+275590_630149.03334.0DomainLaminin EGF-like 6
HgeneLAMA3chr18:21294036chr18:21095820ENST00000313654+275631_683149.03334.0DomainLaminin EGF-like 7
HgeneLAMA3chr18:21294036chr18:21095820ENST00000313654+275684_728149.03334.0DomainLaminin EGF-like 8
HgeneLAMA3chr18:21294036chr18:21095820ENST00000399516+2741266_1311149.03278.0DomainLaminin EGF-like 9
HgeneLAMA3chr18:21294036chr18:21095820ENST00000399516+2741312_1355149.03278.0DomainLaminin EGF-like 10
HgeneLAMA3chr18:21294036chr18:21095820ENST00000399516+2741356_1404149.03278.0DomainLaminin EGF-like 11
HgeneLAMA3chr18:21294036chr18:21095820ENST00000399516+2741405_1455149.03278.0DomainLaminin EGF-like 12
HgeneLAMA3chr18:21294036chr18:21095820ENST00000399516+2741476_1653149.03278.0DomainLaminin IV type A
HgeneLAMA3chr18:21294036chr18:21095820ENST00000399516+2741687_1733149.03278.0DomainLaminin EGF-like 13
HgeneLAMA3chr18:21294036chr18:21095820ENST00000399516+2741734_1786149.03278.0DomainLaminin EGF-like 14
HgeneLAMA3chr18:21294036chr18:21095820ENST00000399516+2741787_1821149.03278.0DomainLaminin EGF-like 15%3B truncated
HgeneLAMA3chr18:21294036chr18:21095820ENST00000399516+2742390_2591149.03278.0DomainLaminin G-like 1
HgeneLAMA3chr18:21294036chr18:21095820ENST00000399516+2742598_2760149.03278.0DomainLaminin G-like 2
HgeneLAMA3chr18:21294036chr18:21095820ENST00000399516+2742767_2927149.03278.0DomainLaminin G-like 3
HgeneLAMA3chr18:21294036chr18:21095820ENST00000399516+2742986_3150149.03278.0DomainLaminin G-like 4
HgeneLAMA3chr18:21294036chr18:21095820ENST00000399516+274299_355149.03278.0DomainLaminin EGF-like 1
HgeneLAMA3chr18:21294036chr18:21095820ENST00000399516+2743157_3330149.03278.0DomainLaminin G-like 5
HgeneLAMA3chr18:21294036chr18:21095820ENST00000399516+274356_425149.03278.0DomainLaminin EGF-like 2
HgeneLAMA3chr18:21294036chr18:21095820ENST00000399516+274426_469149.03278.0DomainLaminin EGF-like 3
HgeneLAMA3chr18:21294036chr18:21095820ENST00000399516+27443_298149.03278.0DomainLaminin N-terminal
HgeneLAMA3chr18:21294036chr18:21095820ENST00000399516+274491_535149.03278.0DomainLaminin EGF-like 4
HgeneLAMA3chr18:21294036chr18:21095820ENST00000399516+274536_588149.03278.0DomainLaminin EGF-like 5
HgeneLAMA3chr18:21294036chr18:21095820ENST00000399516+274590_630149.03278.0DomainLaminin EGF-like 6
HgeneLAMA3chr18:21294036chr18:21095820ENST00000399516+274631_683149.03278.0DomainLaminin EGF-like 7
HgeneLAMA3chr18:21294036chr18:21095820ENST00000399516+274684_728149.03278.0DomainLaminin EGF-like 8
HgeneLAMA3chr18:21294036chr18:21095820ENST00000587184+1371266_13110.01669.0DomainLaminin EGF-like 9
HgeneLAMA3chr18:21294036chr18:21095820ENST00000587184+1371312_13550.01669.0DomainLaminin EGF-like 10
HgeneLAMA3chr18:21294036chr18:21095820ENST00000587184+1371356_14040.01669.0DomainLaminin EGF-like 11
HgeneLAMA3chr18:21294036chr18:21095820ENST00000587184+1371405_14550.01669.0DomainLaminin EGF-like 12
HgeneLAMA3chr18:21294036chr18:21095820ENST00000587184+1371476_16530.01669.0DomainLaminin IV type A
HgeneLAMA3chr18:21294036chr18:21095820ENST00000587184+1371687_17330.01669.0DomainLaminin EGF-like 13
HgeneLAMA3chr18:21294036chr18:21095820ENST00000587184+1371734_17860.01669.0DomainLaminin EGF-like 14
HgeneLAMA3chr18:21294036chr18:21095820ENST00000587184+1371787_18210.01669.0DomainLaminin EGF-like 15%3B truncated
HgeneLAMA3chr18:21294036chr18:21095820ENST00000587184+1372390_25910.01669.0DomainLaminin G-like 1
HgeneLAMA3chr18:21294036chr18:21095820ENST00000587184+1372598_27600.01669.0DomainLaminin G-like 2
HgeneLAMA3chr18:21294036chr18:21095820ENST00000587184+1372767_29270.01669.0DomainLaminin G-like 3
HgeneLAMA3chr18:21294036chr18:21095820ENST00000587184+1372986_31500.01669.0DomainLaminin G-like 4
HgeneLAMA3chr18:21294036chr18:21095820ENST00000587184+137299_3550.01669.0DomainLaminin EGF-like 1
HgeneLAMA3chr18:21294036chr18:21095820ENST00000587184+1373157_33300.01669.0DomainLaminin G-like 5
HgeneLAMA3chr18:21294036chr18:21095820ENST00000587184+137356_4250.01669.0DomainLaminin EGF-like 2
HgeneLAMA3chr18:21294036chr18:21095820ENST00000587184+137426_4690.01669.0DomainLaminin EGF-like 3
HgeneLAMA3chr18:21294036chr18:21095820ENST00000587184+13743_2980.01669.0DomainLaminin N-terminal
HgeneLAMA3chr18:21294036chr18:21095820ENST00000587184+137491_5350.01669.0DomainLaminin EGF-like 4
HgeneLAMA3chr18:21294036chr18:21095820ENST00000587184+137536_5880.01669.0DomainLaminin EGF-like 5
HgeneLAMA3chr18:21294036chr18:21095820ENST00000587184+137590_6300.01669.0DomainLaminin EGF-like 6
HgeneLAMA3chr18:21294036chr18:21095820ENST00000587184+137631_6830.01669.0DomainLaminin EGF-like 7
HgeneLAMA3chr18:21294036chr18:21095820ENST00000587184+137684_7280.01669.0DomainLaminin EGF-like 8
HgeneLAMA3chr18:21294036chr18:21109143ENST00000313654+2751266_1311149.03334.0DomainLaminin EGF-like 9
HgeneLAMA3chr18:21294036chr18:21109143ENST00000313654+2751312_1355149.03334.0DomainLaminin EGF-like 10
HgeneLAMA3chr18:21294036chr18:21109143ENST00000313654+2751356_1404149.03334.0DomainLaminin EGF-like 11
HgeneLAMA3chr18:21294036chr18:21109143ENST00000313654+2751405_1455149.03334.0DomainLaminin EGF-like 12
HgeneLAMA3chr18:21294036chr18:21109143ENST00000313654+2751476_1653149.03334.0DomainLaminin IV type A
HgeneLAMA3chr18:21294036chr18:21109143ENST00000313654+2751687_1733149.03334.0DomainLaminin EGF-like 13
HgeneLAMA3chr18:21294036chr18:21109143ENST00000313654+2751734_1786149.03334.0DomainLaminin EGF-like 14
HgeneLAMA3chr18:21294036chr18:21109143ENST00000313654+2751787_1821149.03334.0DomainLaminin EGF-like 15%3B truncated
HgeneLAMA3chr18:21294036chr18:21109143ENST00000313654+2752390_2591149.03334.0DomainLaminin G-like 1
HgeneLAMA3chr18:21294036chr18:21109143ENST00000313654+2752598_2760149.03334.0DomainLaminin G-like 2
HgeneLAMA3chr18:21294036chr18:21109143ENST00000313654+2752767_2927149.03334.0DomainLaminin G-like 3
HgeneLAMA3chr18:21294036chr18:21109143ENST00000313654+2752986_3150149.03334.0DomainLaminin G-like 4
HgeneLAMA3chr18:21294036chr18:21109143ENST00000313654+275299_355149.03334.0DomainLaminin EGF-like 1
HgeneLAMA3chr18:21294036chr18:21109143ENST00000313654+2753157_3330149.03334.0DomainLaminin G-like 5
HgeneLAMA3chr18:21294036chr18:21109143ENST00000313654+275356_425149.03334.0DomainLaminin EGF-like 2
HgeneLAMA3chr18:21294036chr18:21109143ENST00000313654+275426_469149.03334.0DomainLaminin EGF-like 3
HgeneLAMA3chr18:21294036chr18:21109143ENST00000313654+27543_298149.03334.0DomainLaminin N-terminal
HgeneLAMA3chr18:21294036chr18:21109143ENST00000313654+275491_535149.03334.0DomainLaminin EGF-like 4
HgeneLAMA3chr18:21294036chr18:21109143ENST00000313654+275536_588149.03334.0DomainLaminin EGF-like 5
HgeneLAMA3chr18:21294036chr18:21109143ENST00000313654+275590_630149.03334.0DomainLaminin EGF-like 6
HgeneLAMA3chr18:21294036chr18:21109143ENST00000313654+275631_683149.03334.0DomainLaminin EGF-like 7
HgeneLAMA3chr18:21294036chr18:21109143ENST00000313654+275684_728149.03334.0DomainLaminin EGF-like 8
HgeneLAMA3chr18:21294036chr18:21109143ENST00000399516+2741266_1311149.03278.0DomainLaminin EGF-like 9
HgeneLAMA3chr18:21294036chr18:21109143ENST00000399516+2741312_1355149.03278.0DomainLaminin EGF-like 10
HgeneLAMA3chr18:21294036chr18:21109143ENST00000399516+2741356_1404149.03278.0DomainLaminin EGF-like 11
HgeneLAMA3chr18:21294036chr18:21109143ENST00000399516+2741405_1455149.03278.0DomainLaminin EGF-like 12
HgeneLAMA3chr18:21294036chr18:21109143ENST00000399516+2741476_1653149.03278.0DomainLaminin IV type A
HgeneLAMA3chr18:21294036chr18:21109143ENST00000399516+2741687_1733149.03278.0DomainLaminin EGF-like 13
HgeneLAMA3chr18:21294036chr18:21109143ENST00000399516+2741734_1786149.03278.0DomainLaminin EGF-like 14
HgeneLAMA3chr18:21294036chr18:21109143ENST00000399516+2741787_1821149.03278.0DomainLaminin EGF-like 15%3B truncated
HgeneLAMA3chr18:21294036chr18:21109143ENST00000399516+2742390_2591149.03278.0DomainLaminin G-like 1
HgeneLAMA3chr18:21294036chr18:21109143ENST00000399516+2742598_2760149.03278.0DomainLaminin G-like 2
HgeneLAMA3chr18:21294036chr18:21109143ENST00000399516+2742767_2927149.03278.0DomainLaminin G-like 3
HgeneLAMA3chr18:21294036chr18:21109143ENST00000399516+2742986_3150149.03278.0DomainLaminin G-like 4
HgeneLAMA3chr18:21294036chr18:21109143ENST00000399516+274299_355149.03278.0DomainLaminin EGF-like 1
HgeneLAMA3chr18:21294036chr18:21109143ENST00000399516+2743157_3330149.03278.0DomainLaminin G-like 5
HgeneLAMA3chr18:21294036chr18:21109143ENST00000399516+274356_425149.03278.0DomainLaminin EGF-like 2
HgeneLAMA3chr18:21294036chr18:21109143ENST00000399516+274426_469149.03278.0DomainLaminin EGF-like 3
HgeneLAMA3chr18:21294036chr18:21109143ENST00000399516+27443_298149.03278.0DomainLaminin N-terminal
HgeneLAMA3chr18:21294036chr18:21109143ENST00000399516+274491_535149.03278.0DomainLaminin EGF-like 4
HgeneLAMA3chr18:21294036chr18:21109143ENST00000399516+274536_588149.03278.0DomainLaminin EGF-like 5
HgeneLAMA3chr18:21294036chr18:21109143ENST00000399516+274590_630149.03278.0DomainLaminin EGF-like 6
HgeneLAMA3chr18:21294036chr18:21109143ENST00000399516+274631_683149.03278.0DomainLaminin EGF-like 7
HgeneLAMA3chr18:21294036chr18:21109143ENST00000399516+274684_728149.03278.0DomainLaminin EGF-like 8
HgeneLAMA3chr18:21294036chr18:21109143ENST00000587184+1371266_13110.01669.0DomainLaminin EGF-like 9
HgeneLAMA3chr18:21294036chr18:21109143ENST00000587184+1371312_13550.01669.0DomainLaminin EGF-like 10
HgeneLAMA3chr18:21294036chr18:21109143ENST00000587184+1371356_14040.01669.0DomainLaminin EGF-like 11
HgeneLAMA3chr18:21294036chr18:21109143ENST00000587184+1371405_14550.01669.0DomainLaminin EGF-like 12
HgeneLAMA3chr18:21294036chr18:21109143ENST00000587184+1371476_16530.01669.0DomainLaminin IV type A
HgeneLAMA3chr18:21294036chr18:21109143ENST00000587184+1371687_17330.01669.0DomainLaminin EGF-like 13
HgeneLAMA3chr18:21294036chr18:21109143ENST00000587184+1371734_17860.01669.0DomainLaminin EGF-like 14
HgeneLAMA3chr18:21294036chr18:21109143ENST00000587184+1371787_18210.01669.0DomainLaminin EGF-like 15%3B truncated
HgeneLAMA3chr18:21294036chr18:21109143ENST00000587184+1372390_25910.01669.0DomainLaminin G-like 1
HgeneLAMA3chr18:21294036chr18:21109143ENST00000587184+1372598_27600.01669.0DomainLaminin G-like 2
HgeneLAMA3chr18:21294036chr18:21109143ENST00000587184+1372767_29270.01669.0DomainLaminin G-like 3
HgeneLAMA3chr18:21294036chr18:21109143ENST00000587184+1372986_31500.01669.0DomainLaminin G-like 4
HgeneLAMA3chr18:21294036chr18:21109143ENST00000587184+137299_3550.01669.0DomainLaminin EGF-like 1
HgeneLAMA3chr18:21294036chr18:21109143ENST00000587184+1373157_33300.01669.0DomainLaminin G-like 5
HgeneLAMA3chr18:21294036chr18:21109143ENST00000587184+137356_4250.01669.0DomainLaminin EGF-like 2
HgeneLAMA3chr18:21294036chr18:21109143ENST00000587184+137426_4690.01669.0DomainLaminin EGF-like 3
HgeneLAMA3chr18:21294036chr18:21109143ENST00000587184+13743_2980.01669.0DomainLaminin N-terminal
HgeneLAMA3chr18:21294036chr18:21109143ENST00000587184+137491_5350.01669.0DomainLaminin EGF-like 4
HgeneLAMA3chr18:21294036chr18:21109143ENST00000587184+137536_5880.01669.0DomainLaminin EGF-like 5
HgeneLAMA3chr18:21294036chr18:21109143ENST00000587184+137590_6300.01669.0DomainLaminin EGF-like 6
HgeneLAMA3chr18:21294036chr18:21109143ENST00000587184+137631_6830.01669.0DomainLaminin EGF-like 7
HgeneLAMA3chr18:21294036chr18:21109143ENST00000587184+137684_7280.01669.0DomainLaminin EGF-like 8
HgeneLAMA3chr18:21294036chr18:21095820ENST00000313654+2752278_2280149.03334.0MotifCell attachment site
HgeneLAMA3chr18:21294036chr18:21095820ENST00000399516+2742278_2280149.03278.0MotifCell attachment site
HgeneLAMA3chr18:21294036chr18:21095820ENST00000587184+1372278_22800.01669.0MotifCell attachment site
HgeneLAMA3chr18:21294036chr18:21109143ENST00000313654+2752278_2280149.03334.0MotifCell attachment site
HgeneLAMA3chr18:21294036chr18:21109143ENST00000399516+2742278_2280149.03278.0MotifCell attachment site
HgeneLAMA3chr18:21294036chr18:21109143ENST00000587184+1372278_22800.01669.0MotifCell attachment site
HgeneLAMA3chr18:21294036chr18:21095820ENST00000313654+2751266_1465149.03334.0RegionNote=Domain III B
HgeneLAMA3chr18:21294036chr18:21095820ENST00000313654+2751654_1821149.03334.0RegionNote=Domain III A
HgeneLAMA3chr18:21294036chr18:21095820ENST00000313654+2751822_2389149.03334.0RegionNote=Domain II and I
HgeneLAMA3chr18:21294036chr18:21095820ENST00000313654+275298_728149.03334.0RegionNote=Domain V
HgeneLAMA3chr18:21294036chr18:21095820ENST00000313654+275796_1265149.03334.0RegionNote=Domain IV 1 (domain IV B)
HgeneLAMA3chr18:21294036chr18:21095820ENST00000399516+2741266_1465149.03278.0RegionNote=Domain III B
HgeneLAMA3chr18:21294036chr18:21095820ENST00000399516+2741654_1821149.03278.0RegionNote=Domain III A
HgeneLAMA3chr18:21294036chr18:21095820ENST00000399516+2741822_2389149.03278.0RegionNote=Domain II and I
HgeneLAMA3chr18:21294036chr18:21095820ENST00000399516+274298_728149.03278.0RegionNote=Domain V
HgeneLAMA3chr18:21294036chr18:21095820ENST00000399516+274796_1265149.03278.0RegionNote=Domain IV 1 (domain IV B)
HgeneLAMA3chr18:21294036chr18:21095820ENST00000587184+1371266_14650.01669.0RegionNote=Domain III B
HgeneLAMA3chr18:21294036chr18:21095820ENST00000587184+1371654_18210.01669.0RegionNote=Domain III A
HgeneLAMA3chr18:21294036chr18:21095820ENST00000587184+1371822_23890.01669.0RegionNote=Domain II and I
HgeneLAMA3chr18:21294036chr18:21095820ENST00000587184+137298_7280.01669.0RegionNote=Domain V
HgeneLAMA3chr18:21294036chr18:21095820ENST00000587184+137796_12650.01669.0RegionNote=Domain IV 1 (domain IV B)
HgeneLAMA3chr18:21294036chr18:21109143ENST00000313654+2751266_1465149.03334.0RegionNote=Domain III B
HgeneLAMA3chr18:21294036chr18:21109143ENST00000313654+2751654_1821149.03334.0RegionNote=Domain III A
HgeneLAMA3chr18:21294036chr18:21109143ENST00000313654+2751822_2389149.03334.0RegionNote=Domain II and I
HgeneLAMA3chr18:21294036chr18:21109143ENST00000313654+275298_728149.03334.0RegionNote=Domain V
HgeneLAMA3chr18:21294036chr18:21109143ENST00000313654+275796_1265149.03334.0RegionNote=Domain IV 1 (domain IV B)
HgeneLAMA3chr18:21294036chr18:21109143ENST00000399516+2741266_1465149.03278.0RegionNote=Domain III B
HgeneLAMA3chr18:21294036chr18:21109143ENST00000399516+2741654_1821149.03278.0RegionNote=Domain III A
HgeneLAMA3chr18:21294036chr18:21109143ENST00000399516+2741822_2389149.03278.0RegionNote=Domain II and I
HgeneLAMA3chr18:21294036chr18:21109143ENST00000399516+274298_728149.03278.0RegionNote=Domain V
HgeneLAMA3chr18:21294036chr18:21109143ENST00000399516+274796_1265149.03278.0RegionNote=Domain IV 1 (domain IV B)
HgeneLAMA3chr18:21294036chr18:21109143ENST00000587184+1371266_14650.01669.0RegionNote=Domain III B
HgeneLAMA3chr18:21294036chr18:21109143ENST00000587184+1371654_18210.01669.0RegionNote=Domain III A
HgeneLAMA3chr18:21294036chr18:21109143ENST00000587184+1371822_23890.01669.0RegionNote=Domain II and I
HgeneLAMA3chr18:21294036chr18:21109143ENST00000587184+137298_7280.01669.0RegionNote=Domain V
HgeneLAMA3chr18:21294036chr18:21109143ENST00000587184+137796_12650.01669.0RegionNote=Domain IV 1 (domain IV B)


Top

Fusion Gene Sequence for LAMA3-C18orf8


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000313654_ENST00000269221_TCGA-55-A493-01A_LAMA3_chr18_21294036_+_C18orf8_chr18_21109143_length(transcript)=1444nt_BP=688nt
GAGCGCTGTCAGTTCCTGATCCGGCTGGTGCCCGCTCCAGCCGCGGCAGGTTCCAGAGCTGAGAGGCCACCCCCACGCCGCGGGCTTCCA
GCGCGTGGAGCAAGGGGAGCGGCCCCGGCGCCGCCCATATCCCCGGCTGCGCTAGTCCTGGCGCTGCAGGTCCGGGAGGCGCAGGCGGAG
AGCGGCGGTGCCCCCGAGCCCCTCTGCGGACGGCTCAGGCGGGAGGACCCCGCGCGGCTGGATGGCGGCGGCCGCGCGGCCTCGGGGTCG
GGCACTGGGGCCAGTACTGCCGCCGACGCCGCTGCTCCTGCTGGTACTGCGGGTGCTGCCAGCCTGCGGGGCGACCGCTCGGGATCCCGG
GGCCGCGGCCGGGCTCAGCCTTCACCCGACTTACTTCAACCTGGCCGAGGCGGCGAGGATTTGGGCCACCGCCACCTGCGGGGAGAGGGG
ACCCGGCGAGGGGAGGCCCCAGCCCGAGCTCTACTGCAAGTTGGTCGGGGGCCCCACCGCCCCAGGCAGCGGCCACACCATCCAGGGCCA
GTTCTGTGACTATTGCAATTCTGAAGACCCCAGGAAAGCACATCCTGTCACCAATGCCATCGATGGATCTGAACGTTGGTGGCAAAGCCC
TCCCCTGTCCTCAGGCACACAGTACAACAGAGTCAACCTCACCTTGGATCTGGGGCAGGCGGTGGAAGCAGGGCAGAGCCGAAGCAGCCC
GCTCCTCAAGAGGCCGGTGCGGACCCAGGCGGTGCTGGACCAGTCAGATGTGTACACCCATGTCCTGTCAGCCTTTGTGGAAAAGAAGGA
GATGCCTCATAAATTTGTGATAGCCGTGCTGATGGAATACATTCGTTCTCTTAACCAGTTTCAGATTGCAGTACAGCATTACCTACATGA
ACTTGTTATCAAAACCCTTGTCCAGCACAACCTCTTTTATATGCTGCATCAGTTCCTGCAGTACCACGTCCTCAGCGACTCCAAACCTTT
GGCTTGTCTGCTGTTATCCCTAGAGAGTTTCTATCCTCCTGCTCATCAGCTATCTCTGGACATGCTGAAGCGACTTTCAACAGCAAATGA
TGAAATAGTAGAAGTTCTCCTTTCCAAACACCAAGTGTTAGCTGCCTTAAGGTTTATCCGGGGCATTGGTGGCCATGACAACATTTCTGC
ACGAAAATTTTTAGATGCTGCAAAGCAGACTGAAGACAACATGCTTTTCTATACAATATTCCGCTTTTTTGAACAGCGAAACCAGCGTTT
GCGAGGGAGCCCCAATTTCACACCAGGGGAACACTGTGAAGAACATGTTGCTTTTTTCAAACAGATTTTTGGAGACCAAGCTCTAATGAG
GCCTACAACATTCTGAAATCACTTGCTGTTTTTTTATATAAAAATGTGTACAAAGTTAATTTATTGCATTAATAAAGCTCTTTAAACTAT

>In-frame_ENST00000313654_ENST00000269221_TCGA-55-A493-01A_LAMA3_chr18_21294036_+_C18orf8_chr18_21109143_length(amino acids)=374AA_start in transcript=241_stop in transcript=1365
MAAAARPRGRALGPVLPPTPLLLLVLRVLPACGATARDPGAAAGLSLHPTYFNLAEAARIWATATCGERGPGEGRPQPELYCKLVGGPTA
PGSGHTIQGQFCDYCNSEDPRKAHPVTNAIDGSERWWQSPPLSSGTQYNRVNLTLDLGQAVEAGQSRSSPLLKRPVRTQAVLDQSDVYTH
VLSAFVEKKEMPHKFVIAVLMEYIRSLNQFQIAVQHYLHELVIKTLVQHNLFYMLHQFLQYHVLSDSKPLACLLLSLESFYPPAHQLSLD
MLKRLSTANDEIVEVLLSKHQVLAALRFIRGIGGHDNISARKFLDAAKQTEDNMLFYTIFRFFEQRNQRLRGSPNFTPGEHCEEHVAFFK

--------------------------------------------------------------
>In-frame_ENST00000313654_ENST00000590868_TCGA-55-A493-01A_LAMA3_chr18_21294036_+_C18orf8_chr18_21109143_length(transcript)=1438nt_BP=688nt
GAGCGCTGTCAGTTCCTGATCCGGCTGGTGCCCGCTCCAGCCGCGGCAGGTTCCAGAGCTGAGAGGCCACCCCCACGCCGCGGGCTTCCA
GCGCGTGGAGCAAGGGGAGCGGCCCCGGCGCCGCCCATATCCCCGGCTGCGCTAGTCCTGGCGCTGCAGGTCCGGGAGGCGCAGGCGGAG
AGCGGCGGTGCCCCCGAGCCCCTCTGCGGACGGCTCAGGCGGGAGGACCCCGCGCGGCTGGATGGCGGCGGCCGCGCGGCCTCGGGGTCG
GGCACTGGGGCCAGTACTGCCGCCGACGCCGCTGCTCCTGCTGGTACTGCGGGTGCTGCCAGCCTGCGGGGCGACCGCTCGGGATCCCGG
GGCCGCGGCCGGGCTCAGCCTTCACCCGACTTACTTCAACCTGGCCGAGGCGGCGAGGATTTGGGCCACCGCCACCTGCGGGGAGAGGGG
ACCCGGCGAGGGGAGGCCCCAGCCCGAGCTCTACTGCAAGTTGGTCGGGGGCCCCACCGCCCCAGGCAGCGGCCACACCATCCAGGGCCA
GTTCTGTGACTATTGCAATTCTGAAGACCCCAGGAAAGCACATCCTGTCACCAATGCCATCGATGGATCTGAACGTTGGTGGCAAAGCCC
TCCCCTGTCCTCAGGCACACAGTACAACAGAGTCAACCTCACCTTGGATCTGGGGCAGGCGGTGGAAGCAGGGCAGAGCCGAAGCAGCCC
GCTCCTCAAGAGGCCGGTGCGGACCCAGGCGGTGCTGGACCAGTCAGATGTGTACACCCATGTCCTGTCAGCCTTTGTGGAAAAGAAGGA
GATGCCTCATAAATTTGTGATAGCCGTGCTGATGGAATACATTCGTTCTCTTAACCAGTTTCAGATTGCAGTACAGCATTACCTACATGA
ACTTGTTATCAAAACCCTTGTCCAGCACAACCTCTTTTATATGCTGCATCAGTTCCTGCAGTACCACGTCCTCAGCGACTCCAAACCTTT
GGCTTGTCTGCTGTTATCCCTAGAGAGTTTCTATCCTCCTGCTCATCAGCTATCTCTGGACATGCTGAAGCGACTTTCAACAGCAAATGA
TGAAATAGTAGAAGTTCTCCTTTCCAAACACCAAGTGTTAGCTGCCTTAAGGTTTATCCGGGGCATTGGTGGCCATGACAACATTTCTGC
ACGAAAATTTTTAGATGCTGCAAAGCAGACTGAAGACAACATGCTTTTCTATACAATATTCCGCTTTTTTGAACAGCGAAACCAGCGTTT
GCGAGGGAGCCCCAATTTCACACCAGGGGAACACTGTGAAGAACATGTTGCTTTTTTCAAACAGATTTTTGGAGACCAAGCTCTAATGAG

>In-frame_ENST00000313654_ENST00000590868_TCGA-55-A493-01A_LAMA3_chr18_21294036_+_C18orf8_chr18_21109143_length(amino acids)=374AA_start in transcript=241_stop in transcript=1365
MAAAARPRGRALGPVLPPTPLLLLVLRVLPACGATARDPGAAAGLSLHPTYFNLAEAARIWATATCGERGPGEGRPQPELYCKLVGGPTA
PGSGHTIQGQFCDYCNSEDPRKAHPVTNAIDGSERWWQSPPLSSGTQYNRVNLTLDLGQAVEAGQSRSSPLLKRPVRTQAVLDQSDVYTH
VLSAFVEKKEMPHKFVIAVLMEYIRSLNQFQIAVQHYLHELVIKTLVQHNLFYMLHQFLQYHVLSDSKPLACLLLSLESFYPPAHQLSLD
MLKRLSTANDEIVEVLLSKHQVLAALRFIRGIGGHDNISARKFLDAAKQTEDNMLFYTIFRFFEQRNQRLRGSPNFTPGEHCEEHVAFFK

--------------------------------------------------------------
>In-frame_ENST00000399516_ENST00000269221_TCGA-55-A493-01A_LAMA3_chr18_21294036_+_C18orf8_chr18_21109143_length(transcript)=1203nt_BP=447nt
ATGGCGGCGGCCGCGCGGCCTCGGGGTCGGGCACTGGGGCCAGTACTGCCGCCGACGCCGCTGCTCCTGCTGGTACTGCGGGTGCTGCCA
GCCTGCGGGGCGACCGCTCGGGATCCCGGGGCCGCGGCCGGGCTCAGCCTTCACCCGACTTACTTCAACCTGGCCGAGGCGGCGAGGATT
TGGGCCACCGCCACCTGCGGGGAGAGGGGACCCGGCGAGGGGAGGCCCCAGCCCGAGCTCTACTGCAAGTTGGTCGGGGGCCCCACCGCC
CCAGGCAGCGGCCACACCATCCAGGGCCAGTTCTGTGACTATTGCAATTCTGAAGACCCCAGGAAAGCACATCCTGTCACCAATGCCATC
GATGGATCTGAACGTTGGTGGCAAAGCCCTCCCCTGTCCTCAGGCACACAGTACAACAGAGTCAACCTCACCTTGGATCTGGGGCAGGCG
GTGGAAGCAGGGCAGAGCCGAAGCAGCCCGCTCCTCAAGAGGCCGGTGCGGACCCAGGCGGTGCTGGACCAGTCAGATGTGTACACCCAT
GTCCTGTCAGCCTTTGTGGAAAAGAAGGAGATGCCTCATAAATTTGTGATAGCCGTGCTGATGGAATACATTCGTTCTCTTAACCAGTTT
CAGATTGCAGTACAGCATTACCTACATGAACTTGTTATCAAAACCCTTGTCCAGCACAACCTCTTTTATATGCTGCATCAGTTCCTGCAG
TACCACGTCCTCAGCGACTCCAAACCTTTGGCTTGTCTGCTGTTATCCCTAGAGAGTTTCTATCCTCCTGCTCATCAGCTATCTCTGGAC
ATGCTGAAGCGACTTTCAACAGCAAATGATGAAATAGTAGAAGTTCTCCTTTCCAAACACCAAGTGTTAGCTGCCTTAAGGTTTATCCGG
GGCATTGGTGGCCATGACAACATTTCTGCACGAAAATTTTTAGATGCTGCAAAGCAGACTGAAGACAACATGCTTTTCTATACAATATTC
CGCTTTTTTGAACAGCGAAACCAGCGTTTGCGAGGGAGCCCCAATTTCACACCAGGGGAACACTGTGAAGAACATGTTGCTTTTTTCAAA
CAGATTTTTGGAGACCAAGCTCTAATGAGGCCTACAACATTCTGAAATCACTTGCTGTTTTTTTATATAAAAATGTGTACAAAGTTAATT

>In-frame_ENST00000399516_ENST00000269221_TCGA-55-A493-01A_LAMA3_chr18_21294036_+_C18orf8_chr18_21109143_length(amino acids)=374AA_start in transcript=0_stop in transcript=1124
MAAAARPRGRALGPVLPPTPLLLLVLRVLPACGATARDPGAAAGLSLHPTYFNLAEAARIWATATCGERGPGEGRPQPELYCKLVGGPTA
PGSGHTIQGQFCDYCNSEDPRKAHPVTNAIDGSERWWQSPPLSSGTQYNRVNLTLDLGQAVEAGQSRSSPLLKRPVRTQAVLDQSDVYTH
VLSAFVEKKEMPHKFVIAVLMEYIRSLNQFQIAVQHYLHELVIKTLVQHNLFYMLHQFLQYHVLSDSKPLACLLLSLESFYPPAHQLSLD
MLKRLSTANDEIVEVLLSKHQVLAALRFIRGIGGHDNISARKFLDAAKQTEDNMLFYTIFRFFEQRNQRLRGSPNFTPGEHCEEHVAFFK

--------------------------------------------------------------
>In-frame_ENST00000399516_ENST00000590868_TCGA-55-A493-01A_LAMA3_chr18_21294036_+_C18orf8_chr18_21109143_length(transcript)=1197nt_BP=447nt
ATGGCGGCGGCCGCGCGGCCTCGGGGTCGGGCACTGGGGCCAGTACTGCCGCCGACGCCGCTGCTCCTGCTGGTACTGCGGGTGCTGCCA
GCCTGCGGGGCGACCGCTCGGGATCCCGGGGCCGCGGCCGGGCTCAGCCTTCACCCGACTTACTTCAACCTGGCCGAGGCGGCGAGGATT
TGGGCCACCGCCACCTGCGGGGAGAGGGGACCCGGCGAGGGGAGGCCCCAGCCCGAGCTCTACTGCAAGTTGGTCGGGGGCCCCACCGCC
CCAGGCAGCGGCCACACCATCCAGGGCCAGTTCTGTGACTATTGCAATTCTGAAGACCCCAGGAAAGCACATCCTGTCACCAATGCCATC
GATGGATCTGAACGTTGGTGGCAAAGCCCTCCCCTGTCCTCAGGCACACAGTACAACAGAGTCAACCTCACCTTGGATCTGGGGCAGGCG
GTGGAAGCAGGGCAGAGCCGAAGCAGCCCGCTCCTCAAGAGGCCGGTGCGGACCCAGGCGGTGCTGGACCAGTCAGATGTGTACACCCAT
GTCCTGTCAGCCTTTGTGGAAAAGAAGGAGATGCCTCATAAATTTGTGATAGCCGTGCTGATGGAATACATTCGTTCTCTTAACCAGTTT
CAGATTGCAGTACAGCATTACCTACATGAACTTGTTATCAAAACCCTTGTCCAGCACAACCTCTTTTATATGCTGCATCAGTTCCTGCAG
TACCACGTCCTCAGCGACTCCAAACCTTTGGCTTGTCTGCTGTTATCCCTAGAGAGTTTCTATCCTCCTGCTCATCAGCTATCTCTGGAC
ATGCTGAAGCGACTTTCAACAGCAAATGATGAAATAGTAGAAGTTCTCCTTTCCAAACACCAAGTGTTAGCTGCCTTAAGGTTTATCCGG
GGCATTGGTGGCCATGACAACATTTCTGCACGAAAATTTTTAGATGCTGCAAAGCAGACTGAAGACAACATGCTTTTCTATACAATATTC
CGCTTTTTTGAACAGCGAAACCAGCGTTTGCGAGGGAGCCCCAATTTCACACCAGGGGAACACTGTGAAGAACATGTTGCTTTTTTCAAA
CAGATTTTTGGAGACCAAGCTCTAATGAGGCCTACAACATTCTGAAATCACTTGCTGTTTTTTTATATAAAAATGTGTACAAAGTTAATT

>In-frame_ENST00000399516_ENST00000590868_TCGA-55-A493-01A_LAMA3_chr18_21294036_+_C18orf8_chr18_21109143_length(amino acids)=374AA_start in transcript=0_stop in transcript=1124
MAAAARPRGRALGPVLPPTPLLLLVLRVLPACGATARDPGAAAGLSLHPTYFNLAEAARIWATATCGERGPGEGRPQPELYCKLVGGPTA
PGSGHTIQGQFCDYCNSEDPRKAHPVTNAIDGSERWWQSPPLSSGTQYNRVNLTLDLGQAVEAGQSRSSPLLKRPVRTQAVLDQSDVYTH
VLSAFVEKKEMPHKFVIAVLMEYIRSLNQFQIAVQHYLHELVIKTLVQHNLFYMLHQFLQYHVLSDSKPLACLLLSLESFYPPAHQLSLD
MLKRLSTANDEIVEVLLSKHQVLAALRFIRGIGGHDNISARKFLDAAKQTEDNMLFYTIFRFFEQRNQRLRGSPNFTPGEHCEEHVAFFK

--------------------------------------------------------------
>In-frame_ENST00000313654_ENST00000269221_TCGA-43-8115-01A_LAMA3_chr18_21294036_+_C18orf8_chr18_21095820_length(transcript)=2332nt_BP=688nt
GAGCGCTGTCAGTTCCTGATCCGGCTGGTGCCCGCTCCAGCCGCGGCAGGTTCCAGAGCTGAGAGGCCACCCCCACGCCGCGGGCTTCCA
GCGCGTGGAGCAAGGGGAGCGGCCCCGGCGCCGCCCATATCCCCGGCTGCGCTAGTCCTGGCGCTGCAGGTCCGGGAGGCGCAGGCGGAG
AGCGGCGGTGCCCCCGAGCCCCTCTGCGGACGGCTCAGGCGGGAGGACCCCGCGCGGCTGGATGGCGGCGGCCGCGCGGCCTCGGGGTCG
GGCACTGGGGCCAGTACTGCCGCCGACGCCGCTGCTCCTGCTGGTACTGCGGGTGCTGCCAGCCTGCGGGGCGACCGCTCGGGATCCCGG
GGCCGCGGCCGGGCTCAGCCTTCACCCGACTTACTTCAACCTGGCCGAGGCGGCGAGGATTTGGGCCACCGCCACCTGCGGGGAGAGGGG
ACCCGGCGAGGGGAGGCCCCAGCCCGAGCTCTACTGCAAGTTGGTCGGGGGCCCCACCGCCCCAGGCAGCGGCCACACCATCCAGGGCCA
GTTCTGTGACTATTGCAATTCTGAAGACCCCAGGAAAGCACATCCTGTCACCAATGCCATCGATGGATCTGAACGTTGGTGGCAAAGCCC
TCCCCTGTCCTCAGGCACACAGTACAACAGAGTCAACCTCACCTTGGATCTGGGGCAGGTATTACCAGAGAAACGGAGTCTGAAACTCTT
GAAGAGCCACAATCTCAATGTGAATTGGTACATGTACTGCCCCGAGAGCGCCGTGATCTTGCTGTCTACCACGGTCCTGGAGAATGTCCT
GCAGCCTTTTCACTTTAGGGCTGGCACTATGTCGAAGCTGCCCAAATTTGAGATTGAATTACCAGCTGCGCCTAAGTCAACTAAACCCAG
CCTTTCCGAAAGAGACATCGCAATGGCTACCATATACGGGCAGCTGTATGTTCTCTTCTTGAGGCATCATTCTCGGACCTCCAACAGCAC
AGGAGCGGAGGTGGTCCTCTATCATCTACCACGAGAAGGTGCCTGTAAAAAGATGCACATATTGAAGTTAAATAGGACGGGAAAGTTTGC
CCTGAACGTGGTGGACAACCTGGTAGTCGTGCATCATCAGGATACAGAGACATCGGTAATATTCGATATCAAGTTACGGGGAGAGTTTGA
CGGCTCCGTTACCTTCCACCACCCCGTGCTTCCCGCTCGATCGATCCAGCCCTATCAGATCCCCATCACAGGTCCTGCTGCCGTGACCAG
CCAGTCTCCTGTTCCATGTAAACTCTATTCTTCATCTTGGATTGTCTTTCAACCTGACATCATTATCAGCGCAAGCCAAGGTTACCTCTG
GAACCTCCAAGTGAAACTTGAGCCCATAGTAAATCTCTTACCAGACAAAGGAAGACTCATGGACTTTCTCCTCCAGAGAAAGGAATGCAA
GATGGTCATCCTGTCTGTCTGTTCACAGATGTTAAGTGAGTCAGACAGAGCATCGCTGCCCGTGATAGCCACTGTTTTTGATAAACTCAA
CCATGAGTATAAAAAGTACCTGGATGCCGAGCAGAGTTATGCGATGGCGGTGGAAGCAGGGCAGAGCCGAAGCAGCCCGCTCCTCAAGAG
GCCGGTGCGGACCCAGGCGGTGCTGGACCAGTCAGATGTGTACACCCATGTCCTGTCAGCCTTTGTGGAAAAGAAGGAGATGCCTCATAA
ATTTGTGATAGCCGTGCTGATGGAATACATTCGTTCTCTTAACCAGTTTCAGATTGCAGTACAGCATTACCTACATGAACTTGTTATCAA
AACCCTTGTCCAGCACAACCTCTTTTATATGCTGCATCAGTTCCTGCAGTACCACGTCCTCAGCGACTCCAAACCTTTGGCTTGTCTGCT
GTTATCCCTAGAGAGTTTCTATCCTCCTGCTCATCAGCTATCTCTGGACATGCTGAAGCGACTTTCAACAGCAAATGATGAAATAGTAGA
AGTTCTCCTTTCCAAACACCAAGTGTTAGCTGCCTTAAGGTTTATCCGGGGCATTGGTGGCCATGACAACATTTCTGCACGAAAATTTTT
AGATGCTGCAAAGCAGACTGAAGACAACATGCTTTTCTATACAATATTCCGCTTTTTTGAACAGCGAAACCAGCGTTTGCGAGGGAGCCC
CAATTTCACACCAGGGGAACACTGTGAAGAACATGTTGCTTTTTTCAAACAGATTTTTGGAGACCAAGCTCTAATGAGGCCTACAACATT

>In-frame_ENST00000313654_ENST00000269221_TCGA-43-8115-01A_LAMA3_chr18_21294036_+_C18orf8_chr18_21095820_length(amino acids)=670AA_start in transcript=241_stop in transcript=2253
MAAAARPRGRALGPVLPPTPLLLLVLRVLPACGATARDPGAAAGLSLHPTYFNLAEAARIWATATCGERGPGEGRPQPELYCKLVGGPTA
PGSGHTIQGQFCDYCNSEDPRKAHPVTNAIDGSERWWQSPPLSSGTQYNRVNLTLDLGQVLPEKRSLKLLKSHNLNVNWYMYCPESAVIL
LSTTVLENVLQPFHFRAGTMSKLPKFEIELPAAPKSTKPSLSERDIAMATIYGQLYVLFLRHHSRTSNSTGAEVVLYHLPREGACKKMHI
LKLNRTGKFALNVVDNLVVVHHQDTETSVIFDIKLRGEFDGSVTFHHPVLPARSIQPYQIPITGPAAVTSQSPVPCKLYSSSWIVFQPDI
IISASQGYLWNLQVKLEPIVNLLPDKGRLMDFLLQRKECKMVILSVCSQMLSESDRASLPVIATVFDKLNHEYKKYLDAEQSYAMAVEAG
QSRSSPLLKRPVRTQAVLDQSDVYTHVLSAFVEKKEMPHKFVIAVLMEYIRSLNQFQIAVQHYLHELVIKTLVQHNLFYMLHQFLQYHVL
SDSKPLACLLLSLESFYPPAHQLSLDMLKRLSTANDEIVEVLLSKHQVLAALRFIRGIGGHDNISARKFLDAAKQTEDNMLFYTIFRFFE

--------------------------------------------------------------
>In-frame_ENST00000313654_ENST00000590868_TCGA-43-8115-01A_LAMA3_chr18_21294036_+_C18orf8_chr18_21095820_length(transcript)=2326nt_BP=688nt
GAGCGCTGTCAGTTCCTGATCCGGCTGGTGCCCGCTCCAGCCGCGGCAGGTTCCAGAGCTGAGAGGCCACCCCCACGCCGCGGGCTTCCA
GCGCGTGGAGCAAGGGGAGCGGCCCCGGCGCCGCCCATATCCCCGGCTGCGCTAGTCCTGGCGCTGCAGGTCCGGGAGGCGCAGGCGGAG
AGCGGCGGTGCCCCCGAGCCCCTCTGCGGACGGCTCAGGCGGGAGGACCCCGCGCGGCTGGATGGCGGCGGCCGCGCGGCCTCGGGGTCG
GGCACTGGGGCCAGTACTGCCGCCGACGCCGCTGCTCCTGCTGGTACTGCGGGTGCTGCCAGCCTGCGGGGCGACCGCTCGGGATCCCGG
GGCCGCGGCCGGGCTCAGCCTTCACCCGACTTACTTCAACCTGGCCGAGGCGGCGAGGATTTGGGCCACCGCCACCTGCGGGGAGAGGGG
ACCCGGCGAGGGGAGGCCCCAGCCCGAGCTCTACTGCAAGTTGGTCGGGGGCCCCACCGCCCCAGGCAGCGGCCACACCATCCAGGGCCA
GTTCTGTGACTATTGCAATTCTGAAGACCCCAGGAAAGCACATCCTGTCACCAATGCCATCGATGGATCTGAACGTTGGTGGCAAAGCCC
TCCCCTGTCCTCAGGCACACAGTACAACAGAGTCAACCTCACCTTGGATCTGGGGCAGGTATTACCAGAGAAACGGAGTCTGAAACTCTT
GAAGAGCCACAATCTCAATGTGAATTGGTACATGTACTGCCCCGAGAGCGCCGTGATCTTGCTGTCTACCACGGTCCTGGAGAATGTCCT
GCAGCCTTTTCACTTTAGGGCTGGCACTATGTCGAAGCTGCCCAAATTTGAGATTGAATTACCAGCTGCGCCTAAGTCAACTAAACCCAG
CCTTTCCGAAAGAGACATCGCAATGGCTACCATATACGGGCAGCTGTATGTTCTCTTCTTGAGGCATCATTCTCGGACCTCCAACAGCAC
AGGAGCGGAGGTGGTCCTCTATCATCTACCACGAGAAGGTGCCTGTAAAAAGATGCACATATTGAAGTTAAATAGGACGGGAAAGTTTGC
CCTGAACGTGGTGGACAACCTGGTAGTCGTGCATCATCAGGATACAGAGACATCGGTAATATTCGATATCAAGTTACGGGGAGAGTTTGA
CGGCTCCGTTACCTTCCACCACCCCGTGCTTCCCGCTCGATCGATCCAGCCCTATCAGATCCCCATCACAGGTCCTGCTGCCGTGACCAG
CCAGTCTCCTGTTCCATGTAAACTCTATTCTTCATCTTGGATTGTCTTTCAACCTGACATCATTATCAGCGCAAGCCAAGGTTACCTCTG
GAACCTCCAAGTGAAACTTGAGCCCATAGTAAATCTCTTACCAGACAAAGGAAGACTCATGGACTTTCTCCTCCAGAGAAAGGAATGCAA
GATGGTCATCCTGTCTGTCTGTTCACAGATGTTAAGTGAGTCAGACAGAGCATCGCTGCCCGTGATAGCCACTGTTTTTGATAAACTCAA
CCATGAGTATAAAAAGTACCTGGATGCCGAGCAGAGTTATGCGATGGCGGTGGAAGCAGGGCAGAGCCGAAGCAGCCCGCTCCTCAAGAG
GCCGGTGCGGACCCAGGCGGTGCTGGACCAGTCAGATGTGTACACCCATGTCCTGTCAGCCTTTGTGGAAAAGAAGGAGATGCCTCATAA
ATTTGTGATAGCCGTGCTGATGGAATACATTCGTTCTCTTAACCAGTTTCAGATTGCAGTACAGCATTACCTACATGAACTTGTTATCAA
AACCCTTGTCCAGCACAACCTCTTTTATATGCTGCATCAGTTCCTGCAGTACCACGTCCTCAGCGACTCCAAACCTTTGGCTTGTCTGCT
GTTATCCCTAGAGAGTTTCTATCCTCCTGCTCATCAGCTATCTCTGGACATGCTGAAGCGACTTTCAACAGCAAATGATGAAATAGTAGA
AGTTCTCCTTTCCAAACACCAAGTGTTAGCTGCCTTAAGGTTTATCCGGGGCATTGGTGGCCATGACAACATTTCTGCACGAAAATTTTT
AGATGCTGCAAAGCAGACTGAAGACAACATGCTTTTCTATACAATATTCCGCTTTTTTGAACAGCGAAACCAGCGTTTGCGAGGGAGCCC
CAATTTCACACCAGGGGAACACTGTGAAGAACATGTTGCTTTTTTCAAACAGATTTTTGGAGACCAAGCTCTAATGAGGCCTACAACATT

>In-frame_ENST00000313654_ENST00000590868_TCGA-43-8115-01A_LAMA3_chr18_21294036_+_C18orf8_chr18_21095820_length(amino acids)=670AA_start in transcript=241_stop in transcript=2253
MAAAARPRGRALGPVLPPTPLLLLVLRVLPACGATARDPGAAAGLSLHPTYFNLAEAARIWATATCGERGPGEGRPQPELYCKLVGGPTA
PGSGHTIQGQFCDYCNSEDPRKAHPVTNAIDGSERWWQSPPLSSGTQYNRVNLTLDLGQVLPEKRSLKLLKSHNLNVNWYMYCPESAVIL
LSTTVLENVLQPFHFRAGTMSKLPKFEIELPAAPKSTKPSLSERDIAMATIYGQLYVLFLRHHSRTSNSTGAEVVLYHLPREGACKKMHI
LKLNRTGKFALNVVDNLVVVHHQDTETSVIFDIKLRGEFDGSVTFHHPVLPARSIQPYQIPITGPAAVTSQSPVPCKLYSSSWIVFQPDI
IISASQGYLWNLQVKLEPIVNLLPDKGRLMDFLLQRKECKMVILSVCSQMLSESDRASLPVIATVFDKLNHEYKKYLDAEQSYAMAVEAG
QSRSSPLLKRPVRTQAVLDQSDVYTHVLSAFVEKKEMPHKFVIAVLMEYIRSLNQFQIAVQHYLHELVIKTLVQHNLFYMLHQFLQYHVL
SDSKPLACLLLSLESFYPPAHQLSLDMLKRLSTANDEIVEVLLSKHQVLAALRFIRGIGGHDNISARKFLDAAKQTEDNMLFYTIFRFFE

--------------------------------------------------------------
>In-frame_ENST00000399516_ENST00000269221_TCGA-43-8115-01A_LAMA3_chr18_21294036_+_C18orf8_chr18_21095820_length(transcript)=2091nt_BP=447nt
ATGGCGGCGGCCGCGCGGCCTCGGGGTCGGGCACTGGGGCCAGTACTGCCGCCGACGCCGCTGCTCCTGCTGGTACTGCGGGTGCTGCCA
GCCTGCGGGGCGACCGCTCGGGATCCCGGGGCCGCGGCCGGGCTCAGCCTTCACCCGACTTACTTCAACCTGGCCGAGGCGGCGAGGATT
TGGGCCACCGCCACCTGCGGGGAGAGGGGACCCGGCGAGGGGAGGCCCCAGCCCGAGCTCTACTGCAAGTTGGTCGGGGGCCCCACCGCC
CCAGGCAGCGGCCACACCATCCAGGGCCAGTTCTGTGACTATTGCAATTCTGAAGACCCCAGGAAAGCACATCCTGTCACCAATGCCATC
GATGGATCTGAACGTTGGTGGCAAAGCCCTCCCCTGTCCTCAGGCACACAGTACAACAGAGTCAACCTCACCTTGGATCTGGGGCAGGTA
TTACCAGAGAAACGGAGTCTGAAACTCTTGAAGAGCCACAATCTCAATGTGAATTGGTACATGTACTGCCCCGAGAGCGCCGTGATCTTG
CTGTCTACCACGGTCCTGGAGAATGTCCTGCAGCCTTTTCACTTTAGGGCTGGCACTATGTCGAAGCTGCCCAAATTTGAGATTGAATTA
CCAGCTGCGCCTAAGTCAACTAAACCCAGCCTTTCCGAAAGAGACATCGCAATGGCTACCATATACGGGCAGCTGTATGTTCTCTTCTTG
AGGCATCATTCTCGGACCTCCAACAGCACAGGAGCGGAGGTGGTCCTCTATCATCTACCACGAGAAGGTGCCTGTAAAAAGATGCACATA
TTGAAGTTAAATAGGACGGGAAAGTTTGCCCTGAACGTGGTGGACAACCTGGTAGTCGTGCATCATCAGGATACAGAGACATCGGTAATA
TTCGATATCAAGTTACGGGGAGAGTTTGACGGCTCCGTTACCTTCCACCACCCCGTGCTTCCCGCTCGATCGATCCAGCCCTATCAGATC
CCCATCACAGGTCCTGCTGCCGTGACCAGCCAGTCTCCTGTTCCATGTAAACTCTATTCTTCATCTTGGATTGTCTTTCAACCTGACATC
ATTATCAGCGCAAGCCAAGGTTACCTCTGGAACCTCCAAGTGAAACTTGAGCCCATAGTAAATCTCTTACCAGACAAAGGAAGACTCATG
GACTTTCTCCTCCAGAGAAAGGAATGCAAGATGGTCATCCTGTCTGTCTGTTCACAGATGTTAAGTGAGTCAGACAGAGCATCGCTGCCC
GTGATAGCCACTGTTTTTGATAAACTCAACCATGAGTATAAAAAGTACCTGGATGCCGAGCAGAGTTATGCGATGGCGGTGGAAGCAGGG
CAGAGCCGAAGCAGCCCGCTCCTCAAGAGGCCGGTGCGGACCCAGGCGGTGCTGGACCAGTCAGATGTGTACACCCATGTCCTGTCAGCC
TTTGTGGAAAAGAAGGAGATGCCTCATAAATTTGTGATAGCCGTGCTGATGGAATACATTCGTTCTCTTAACCAGTTTCAGATTGCAGTA
CAGCATTACCTACATGAACTTGTTATCAAAACCCTTGTCCAGCACAACCTCTTTTATATGCTGCATCAGTTCCTGCAGTACCACGTCCTC
AGCGACTCCAAACCTTTGGCTTGTCTGCTGTTATCCCTAGAGAGTTTCTATCCTCCTGCTCATCAGCTATCTCTGGACATGCTGAAGCGA
CTTTCAACAGCAAATGATGAAATAGTAGAAGTTCTCCTTTCCAAACACCAAGTGTTAGCTGCCTTAAGGTTTATCCGGGGCATTGGTGGC
CATGACAACATTTCTGCACGAAAATTTTTAGATGCTGCAAAGCAGACTGAAGACAACATGCTTTTCTATACAATATTCCGCTTTTTTGAA
CAGCGAAACCAGCGTTTGCGAGGGAGCCCCAATTTCACACCAGGGGAACACTGTGAAGAACATGTTGCTTTTTTCAAACAGATTTTTGGA
GACCAAGCTCTAATGAGGCCTACAACATTCTGAAATCACTTGCTGTTTTTTTATATAAAAATGTGTACAAAGTTAATTTATTGCATTAAT

>In-frame_ENST00000399516_ENST00000269221_TCGA-43-8115-01A_LAMA3_chr18_21294036_+_C18orf8_chr18_21095820_length(amino acids)=670AA_start in transcript=0_stop in transcript=2012
MAAAARPRGRALGPVLPPTPLLLLVLRVLPACGATARDPGAAAGLSLHPTYFNLAEAARIWATATCGERGPGEGRPQPELYCKLVGGPTA
PGSGHTIQGQFCDYCNSEDPRKAHPVTNAIDGSERWWQSPPLSSGTQYNRVNLTLDLGQVLPEKRSLKLLKSHNLNVNWYMYCPESAVIL
LSTTVLENVLQPFHFRAGTMSKLPKFEIELPAAPKSTKPSLSERDIAMATIYGQLYVLFLRHHSRTSNSTGAEVVLYHLPREGACKKMHI
LKLNRTGKFALNVVDNLVVVHHQDTETSVIFDIKLRGEFDGSVTFHHPVLPARSIQPYQIPITGPAAVTSQSPVPCKLYSSSWIVFQPDI
IISASQGYLWNLQVKLEPIVNLLPDKGRLMDFLLQRKECKMVILSVCSQMLSESDRASLPVIATVFDKLNHEYKKYLDAEQSYAMAVEAG
QSRSSPLLKRPVRTQAVLDQSDVYTHVLSAFVEKKEMPHKFVIAVLMEYIRSLNQFQIAVQHYLHELVIKTLVQHNLFYMLHQFLQYHVL
SDSKPLACLLLSLESFYPPAHQLSLDMLKRLSTANDEIVEVLLSKHQVLAALRFIRGIGGHDNISARKFLDAAKQTEDNMLFYTIFRFFE

--------------------------------------------------------------
>In-frame_ENST00000399516_ENST00000590868_TCGA-43-8115-01A_LAMA3_chr18_21294036_+_C18orf8_chr18_21095820_length(transcript)=2085nt_BP=447nt
ATGGCGGCGGCCGCGCGGCCTCGGGGTCGGGCACTGGGGCCAGTACTGCCGCCGACGCCGCTGCTCCTGCTGGTACTGCGGGTGCTGCCA
GCCTGCGGGGCGACCGCTCGGGATCCCGGGGCCGCGGCCGGGCTCAGCCTTCACCCGACTTACTTCAACCTGGCCGAGGCGGCGAGGATT
TGGGCCACCGCCACCTGCGGGGAGAGGGGACCCGGCGAGGGGAGGCCCCAGCCCGAGCTCTACTGCAAGTTGGTCGGGGGCCCCACCGCC
CCAGGCAGCGGCCACACCATCCAGGGCCAGTTCTGTGACTATTGCAATTCTGAAGACCCCAGGAAAGCACATCCTGTCACCAATGCCATC
GATGGATCTGAACGTTGGTGGCAAAGCCCTCCCCTGTCCTCAGGCACACAGTACAACAGAGTCAACCTCACCTTGGATCTGGGGCAGGTA
TTACCAGAGAAACGGAGTCTGAAACTCTTGAAGAGCCACAATCTCAATGTGAATTGGTACATGTACTGCCCCGAGAGCGCCGTGATCTTG
CTGTCTACCACGGTCCTGGAGAATGTCCTGCAGCCTTTTCACTTTAGGGCTGGCACTATGTCGAAGCTGCCCAAATTTGAGATTGAATTA
CCAGCTGCGCCTAAGTCAACTAAACCCAGCCTTTCCGAAAGAGACATCGCAATGGCTACCATATACGGGCAGCTGTATGTTCTCTTCTTG
AGGCATCATTCTCGGACCTCCAACAGCACAGGAGCGGAGGTGGTCCTCTATCATCTACCACGAGAAGGTGCCTGTAAAAAGATGCACATA
TTGAAGTTAAATAGGACGGGAAAGTTTGCCCTGAACGTGGTGGACAACCTGGTAGTCGTGCATCATCAGGATACAGAGACATCGGTAATA
TTCGATATCAAGTTACGGGGAGAGTTTGACGGCTCCGTTACCTTCCACCACCCCGTGCTTCCCGCTCGATCGATCCAGCCCTATCAGATC
CCCATCACAGGTCCTGCTGCCGTGACCAGCCAGTCTCCTGTTCCATGTAAACTCTATTCTTCATCTTGGATTGTCTTTCAACCTGACATC
ATTATCAGCGCAAGCCAAGGTTACCTCTGGAACCTCCAAGTGAAACTTGAGCCCATAGTAAATCTCTTACCAGACAAAGGAAGACTCATG
GACTTTCTCCTCCAGAGAAAGGAATGCAAGATGGTCATCCTGTCTGTCTGTTCACAGATGTTAAGTGAGTCAGACAGAGCATCGCTGCCC
GTGATAGCCACTGTTTTTGATAAACTCAACCATGAGTATAAAAAGTACCTGGATGCCGAGCAGAGTTATGCGATGGCGGTGGAAGCAGGG
CAGAGCCGAAGCAGCCCGCTCCTCAAGAGGCCGGTGCGGACCCAGGCGGTGCTGGACCAGTCAGATGTGTACACCCATGTCCTGTCAGCC
TTTGTGGAAAAGAAGGAGATGCCTCATAAATTTGTGATAGCCGTGCTGATGGAATACATTCGTTCTCTTAACCAGTTTCAGATTGCAGTA
CAGCATTACCTACATGAACTTGTTATCAAAACCCTTGTCCAGCACAACCTCTTTTATATGCTGCATCAGTTCCTGCAGTACCACGTCCTC
AGCGACTCCAAACCTTTGGCTTGTCTGCTGTTATCCCTAGAGAGTTTCTATCCTCCTGCTCATCAGCTATCTCTGGACATGCTGAAGCGA
CTTTCAACAGCAAATGATGAAATAGTAGAAGTTCTCCTTTCCAAACACCAAGTGTTAGCTGCCTTAAGGTTTATCCGGGGCATTGGTGGC
CATGACAACATTTCTGCACGAAAATTTTTAGATGCTGCAAAGCAGACTGAAGACAACATGCTTTTCTATACAATATTCCGCTTTTTTGAA
CAGCGAAACCAGCGTTTGCGAGGGAGCCCCAATTTCACACCAGGGGAACACTGTGAAGAACATGTTGCTTTTTTCAAACAGATTTTTGGA
GACCAAGCTCTAATGAGGCCTACAACATTCTGAAATCACTTGCTGTTTTTTTATATAAAAATGTGTACAAAGTTAATTTATTGCATTAAT

>In-frame_ENST00000399516_ENST00000590868_TCGA-43-8115-01A_LAMA3_chr18_21294036_+_C18orf8_chr18_21095820_length(amino acids)=670AA_start in transcript=0_stop in transcript=2012
MAAAARPRGRALGPVLPPTPLLLLVLRVLPACGATARDPGAAAGLSLHPTYFNLAEAARIWATATCGERGPGEGRPQPELYCKLVGGPTA
PGSGHTIQGQFCDYCNSEDPRKAHPVTNAIDGSERWWQSPPLSSGTQYNRVNLTLDLGQVLPEKRSLKLLKSHNLNVNWYMYCPESAVIL
LSTTVLENVLQPFHFRAGTMSKLPKFEIELPAAPKSTKPSLSERDIAMATIYGQLYVLFLRHHSRTSNSTGAEVVLYHLPREGACKKMHI
LKLNRTGKFALNVVDNLVVVHHQDTETSVIFDIKLRGEFDGSVTFHHPVLPARSIQPYQIPITGPAAVTSQSPVPCKLYSSSWIVFQPDI
IISASQGYLWNLQVKLEPIVNLLPDKGRLMDFLLQRKECKMVILSVCSQMLSESDRASLPVIATVFDKLNHEYKKYLDAEQSYAMAVEAG
QSRSSPLLKRPVRTQAVLDQSDVYTHVLSAFVEKKEMPHKFVIAVLMEYIRSLNQFQIAVQHYLHELVIKTLVQHNLFYMLHQFLQYHVL
SDSKPLACLLLSLESFYPPAHQLSLDMLKRLSTANDEIVEVLLSKHQVLAALRFIRGIGGHDNISARKFLDAAKQTEDNMLFYTIFRFFE

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for LAMA3-C18orf8


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for LAMA3-C18orf8


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for LAMA3-C18orf8


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneLAMA3C1328355Laryngoonychocutaneous syndrome5CTD_human;GENOMICS_ENGLAND;ORPHANET
HgeneLAMA3C0079683Herlitz Disease4CTD_human;GENOMICS_ENGLAND
HgeneLAMA3C0079301Junctional Epidermolysis Bullosa3CTD_human;GENOMICS_ENGLAND
HgeneLAMA3C0268374Adult junctional epidermolysis bullosa (disorder)3CTD_human;GENOMICS_ENGLAND
HgeneLAMA3C0027339Nail Diseases1CTD_human
HgeneLAMA3C0037299Skin Ulcer1CTD_human
HgeneLAMA3C0079297Epidermolysis Bullosa Progressiva1CTD_human
HgeneLAMA3C0399367Amelogenesis imperfecta local hypoplastic form1GENOMICS_ENGLAND