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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:LGALS8-COPG1 (FusionGDB2 ID:44318)

Fusion Gene Summary for LGALS8-COPG1

check button Fusion gene summary
Fusion gene informationFusion gene name: LGALS8-COPG1
Fusion gene ID: 44318
HgeneTgene
Gene symbol

LGALS8

COPG1

Gene ID

3964

22820

Gene namegalectin 8COPI coat complex subunit gamma 1
SynonymsGal-8|PCTA-1|PCTA1|Po66-CBPCOPG
Cytomap

1q43

3q21.3

Type of geneprotein-codingprotein-coding
Descriptiongalectin-8Po66 carbohydrate binding proteingalectin-8glectin, galactoside-binding, soluble, 8po66 carbohydrate-binding proteinprostate carcinoma tumor antigen 1coatomer subunit gamma-1coat protein gamma-copcoatomer protein complex subunit gamma 1coatomer protein complex, subunit gammacoatomer subunit gammagamma-1-COPgamma-1-coat proteingamma-COPgamma-coat protein
Modification date2020032720200320
UniProtAcc.

Q9Y678

Ensembl transtripts involved in fusion geneENST00000526589, ENST00000527974, 
ENST00000352231, ENST00000341872, 
ENST00000450372, ENST00000366584, 
ENST00000416919, ENST00000323938, 
ENST00000526634, ENST00000525042, 
ENST00000314797, 
Fusion gene scores* DoF score5 X 5 X 4=1004 X 4 X 3=48
# samples 74
** MAII scorelog2(7/100*10)=-0.514573172829758
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/48*10)=-0.263034405833794
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: LGALS8 [Title/Abstract] AND COPG1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointLGALS8(236705010)-COPG1(128993680), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneLGALS8

GO:1904977

lymphatic endothelial cell migration

19268462


check buttonFusion gene breakpoints across LGALS8 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across COPG1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4ESCATCGA-VR-AA7DLGALS8chr1

236705010

+COPG1chr3

128993680

+


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Fusion Gene ORF analysis for LGALS8-COPG1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000526589ENST00000314797LGALS8chr1

236705010

+COPG1chr3

128993680

+
In-frameENST00000527974ENST00000314797LGALS8chr1

236705010

+COPG1chr3

128993680

+
In-frameENST00000352231ENST00000314797LGALS8chr1

236705010

+COPG1chr3

128993680

+
In-frameENST00000341872ENST00000314797LGALS8chr1

236705010

+COPG1chr3

128993680

+
In-frameENST00000450372ENST00000314797LGALS8chr1

236705010

+COPG1chr3

128993680

+
In-frameENST00000366584ENST00000314797LGALS8chr1

236705010

+COPG1chr3

128993680

+
intron-3CDSENST00000416919ENST00000314797LGALS8chr1

236705010

+COPG1chr3

128993680

+
In-frameENST00000323938ENST00000314797LGALS8chr1

236705010

+COPG1chr3

128993680

+
In-frameENST00000526634ENST00000314797LGALS8chr1

236705010

+COPG1chr3

128993680

+
intron-3CDSENST00000525042ENST00000314797LGALS8chr1

236705010

+COPG1chr3

128993680

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000526589LGALS8chr1236705010+ENST00000314797COPG1chr3128993680+175810424601410316
ENST00000527974LGALS8chr1236705010+ENST00000314797COPG1chr3128993680+1387671891039316
ENST00000352231LGALS8chr1236705010+ENST00000314797COPG1chr3128993680+14387221401090316
ENST00000341872LGALS8chr1236705010+ENST00000314797COPG1chr3128993680+16199033211271316
ENST00000450372LGALS8chr1236705010+ENST00000314797COPG1chr3128993680+16199033211271316
ENST00000366584LGALS8chr1236705010+ENST00000314797COPG1chr3128993680+180410885061456316
ENST00000323938LGALS8chr1236705010+ENST00000314797COPG1chr3128993680+129858281950289
ENST00000526634LGALS8chr1236705010+ENST00000314797COPG1chr3128993680+15017852031153316

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000526589ENST00000314797LGALS8chr1236705010+COPG1chr3128993680+0.0022305450.9977695
ENST00000527974ENST00000314797LGALS8chr1236705010+COPG1chr3128993680+0.0016751790.9983248
ENST00000352231ENST00000314797LGALS8chr1236705010+COPG1chr3128993680+0.0017105040.9982895
ENST00000341872ENST00000314797LGALS8chr1236705010+COPG1chr3128993680+0.0021582820.9978417
ENST00000450372ENST00000314797LGALS8chr1236705010+COPG1chr3128993680+0.0021582820.9978417
ENST00000366584ENST00000314797LGALS8chr1236705010+COPG1chr3128993680+0.0024957930.9975042
ENST00000323938ENST00000314797LGALS8chr1236705010+COPG1chr3128993680+0.0005126760.9994873
ENST00000526634ENST00000314797LGALS8chr1236705010+COPG1chr3128993680+0.0014416110.99855834

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Fusion Genomic Features for LGALS8-COPG1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
LGALS8chr1236705010+COPG1chr3128993680+0.0008115350.9991885
LGALS8chr1236705010+COPG1chr3128993680+0.0008115350.9991885

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for LGALS8-COPG1


check button Go to

FGviewer for the breakpoints of chr1:236705010-chr3:128993680

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.COPG1

Q9Y678

FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors. Required for limiting lipid storage in lipid droplets. Involved in lipid homeostasis by regulating the presence of perilipin family members PLIN2 and PLIN3 at the lipid droplet surface and promoting the association of adipocyte triglyceride lipase (PNPLA2) with the lipid droplet surface to mediate lipolysis (By similarity). {ECO:0000250, ECO:0000269|PubMed:20674546}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneLGALS8chr1:236705010chr3:128993680ENST00000341872+71119_152174.0318.0DomainGalectin 1
HgeneLGALS8chr1:236705010chr3:128993680ENST00000352231+71219_152174.0360.0DomainGalectin 1
HgeneLGALS8chr1:236705010chr3:128993680ENST00000366584+61019_152174.0318.0DomainGalectin 1
HgeneLGALS8chr1:236705010chr3:128993680ENST00000450372+71219_152174.0360.0DomainGalectin 1
HgeneLGALS8chr1:236705010chr3:128993680ENST00000526589+91419_152174.0360.0DomainGalectin 1
HgeneLGALS8chr1:236705010chr3:128993680ENST00000526634+61019_152174.0318.0DomainGalectin 1
HgeneLGALS8chr1:236705010chr3:128993680ENST00000527974+61119_152174.0360.0DomainGalectin 1

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneLGALS8chr1:236705010chr3:128993680ENST00000341872+711187_317174.0318.0DomainGalectin 2
HgeneLGALS8chr1:236705010chr3:128993680ENST00000352231+712187_317174.0360.0DomainGalectin 2
HgeneLGALS8chr1:236705010chr3:128993680ENST00000366584+610187_317174.0318.0DomainGalectin 2
HgeneLGALS8chr1:236705010chr3:128993680ENST00000450372+712187_317174.0360.0DomainGalectin 2
HgeneLGALS8chr1:236705010chr3:128993680ENST00000526589+914187_317174.0360.0DomainGalectin 2
HgeneLGALS8chr1:236705010chr3:128993680ENST00000526634+610187_317174.0318.0DomainGalectin 2
HgeneLGALS8chr1:236705010chr3:128993680ENST00000527974+611187_317174.0360.0DomainGalectin 2
HgeneLGALS8chr1:236705010chr3:128993680ENST00000341872+711249_255174.0318.0RegionBeta-galactoside binding
HgeneLGALS8chr1:236705010chr3:128993680ENST00000352231+712249_255174.0360.0RegionBeta-galactoside binding
HgeneLGALS8chr1:236705010chr3:128993680ENST00000366584+610249_255174.0318.0RegionBeta-galactoside binding
HgeneLGALS8chr1:236705010chr3:128993680ENST00000450372+712249_255174.0360.0RegionBeta-galactoside binding
HgeneLGALS8chr1:236705010chr3:128993680ENST00000526589+914249_255174.0360.0RegionBeta-galactoside binding
HgeneLGALS8chr1:236705010chr3:128993680ENST00000526634+610249_255174.0318.0RegionBeta-galactoside binding
HgeneLGALS8chr1:236705010chr3:128993680ENST00000527974+611249_255174.0360.0RegionBeta-galactoside binding
TgeneCOPG1chr1:236705010chr3:128993680ENST000003147972024283_320752.0875.0RepeatNote=HEAT 2
TgeneCOPG1chr1:236705010chr3:128993680ENST000003147972024322_355752.0875.0RepeatNote=HEAT 3
TgeneCOPG1chr1:236705010chr3:128993680ENST000003147972024356_392752.0875.0RepeatNote=HEAT 4
TgeneCOPG1chr1:236705010chr3:128993680ENST00000314797202464_101752.0875.0RepeatNote=HEAT 1


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Fusion Gene Sequence for LGALS8-COPG1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000526589_ENST00000314797_TCGA-VR-AA7D_LGALS8_chr1_236705010_+_COPG1_chr3_128993680_length(transcript)=1758nt_BP=1042nt
AGAACTTCGGAGATTGGGGAAGATAATCGGAAGAGGTAGAAGACACCGTCCATGACACTTCCTGGGGAAGCAGATGTATGTATAAGGATA
GGTGTGTACTGTCAAAAAGCAGCGCCTCCAAGTCTCTTCTGGCACTGTCTGGACTTGGATCCGAGGCAGACGAGGAAGCTGAGAAAACCC
TGGCGTTGACCCCGTGGACCTGGGCGCCCCGGGAAGGCCAGCGCTTGGTCCAGGCAGGCGGGGCCTGTGCGGTGACCACCCTGGTCCTGA
AAAGTCCCAGCCCCGAGCGCCCTCCCTCCTAGACCTGGAGGCCTGGAACAGCCAGCCGCCCACGGACGCCAGAGCCGGGAACCCTGACGG
CACTTAGCTGCTGACAAACAACCTGCTCCGTGGAGCGCCTGAAACACCAGTCTTTGGGGCCAGTGCCTCAGTTTCAATCCAGGTAACCTT
TAAATGAAACTTGCCTAAAATCTTAGGTCATACACAGAAGAGACTCCAATCGACAAGAAGCTGGAAAAGAATGATGTTGTCCTTAAACAA
CCTACAGAATATCATCTATAACCCGGTAATCCCGTTTGTTGGCACCATTCCTGATCAGCTGGATCCTGGAACTTTGATTGTGATACGTGG
GCATGTTCCTAGTGACGCAGACAGATTCCAGGTGGATCTGCAGAATGGCAGCAGCATGAAACCTCGAGCCGATGTGGCCTTTCATTTCAA
TCCTCGTTTCAAAAGGGCCGGCTGCATTGTTTGCAATACTTTGATAAATGAAAAATGGGGACGGGAAGAGATCACCTATGACACGCCTTT
CAAAAGAGAAAAGTCTTTTGAGATCGTGATTATGGTGCTGAAGGACAAATTCCAGGTGGCTGTAAATGGAAAACATACTCTGCTCTATGG
CCACAGGATCGGCCCAGAGAAAATAGACACTCTGGGCATTTATGGCAAAGTGAATATTCACTCAATTGGTTTTAGCTTCAGCTCGGACTT
ACAAAGTACCCAAGCATCTAGTCTGGAACTGACAGAGATAAGTAGAGAAAATCTGGAAGATCTGGAAGTTACTGTAGCTGATCACATTCA
AAAGGTCATGAAACTGAACTTCGAAGCAGCCTGGGATGAGGTAGGGGATGAATTTGAGAAGGAGGAAACGTTCACCTTGTCTACCATCAA
GACACTTGAAGAGGCTGTGGGTAATATTGTGAAGTTCTTGGGAATGCACCCTTGTGAGAGGTCAGACAAAGTGCCGGATAACAAGAACAC
CCACACGTTGCTCCTGGCTGGTGTGTTCCGGGGTGGTCATGACATCCTGGTGCGCTCCCGGCTGCTGCTTTTGGACACAGTGACAATGCA
GGTGACAGCCAGAAGTTTGGAGGAGCTGCCAGTAGACATCATCTTGGCATCTGTGGGATAAGAGGCCAGCCTGCATAGGACCTCATACCC
TTCCCCAACACTACCTGGAAGTTGTGCCTTCCTCATGAAACTGGCAGAAACCCCTTCCCAAGCTTCTGTATTGAAAAACAATTAGGAATC
ATTGCAGATTTTTTTTTATTCTGCTCCCACCTCCCACCCGGGACTACTTGCTGGTGACTTTTTTTTTTTTTTTTTTTAAATAGGGGATGA
TTTTAGCTTGTCCTAAATCTTGCTGTCCACCCTTCCAGGAAAGGGACATTGTAAATGAATAAAACATTCTCAACTCCTCTTGAATCTATC

>In-frame_ENST00000526589_ENST00000314797_TCGA-VR-AA7D_LGALS8_chr1_236705010_+_COPG1_chr3_128993680_length(amino acids)=316AA_start in transcript=460_stop in transcript=1410
MPKILGHTQKRLQSTRSWKRMMLSLNNLQNIIYNPVIPFVGTIPDQLDPGTLIVIRGHVPSDADRFQVDLQNGSSMKPRADVAFHFNPRF
KRAGCIVCNTLINEKWGREEITYDTPFKREKSFEIVIMVLKDKFQVAVNGKHTLLYGHRIGPEKIDTLGIYGKVNIHSIGFSFSSDLQST
QASSLELTEISRENLEDLEVTVADHIQKVMKLNFEAAWDEVGDEFEKEETFTLSTIKTLEEAVGNIVKFLGMHPCERSDKVPDNKNTHTL

--------------------------------------------------------------
>In-frame_ENST00000527974_ENST00000314797_TCGA-VR-AA7D_LGALS8_chr1_236705010_+_COPG1_chr3_128993680_length(transcript)=1387nt_BP=671nt
ACCTGAAAAGACTGGATTTGGGACATGATCCTGTAGAACTTCGGAGGGCCAGTGCCTCAGTTTCAATCCAGGTAACCTTTAAATGAAACT
TGCCTAAAATCTTAGGTCATACACAGAAGAGACTCCAATCGACAAGAAGCTGGAAAAGAATGATGTTGTCCTTAAACAACCTACAGAATA
TCATCTATAACCCGGTAATCCCGTTTGTTGGCACCATTCCTGATCAGCTGGATCCTGGAACTTTGATTGTGATACGTGGGCATGTTCCTA
GTGACGCAGACAGATTCCAGGTGGATCTGCAGAATGGCAGCAGCATGAAACCTCGAGCCGATGTGGCCTTTCATTTCAATCCTCGTTTCA
AAAGGGCCGGCTGCATTGTTTGCAATACTTTGATAAATGAAAAATGGGGACGGGAAGAGATCACCTATGACACGCCTTTCAAAAGAGAAA
AGTCTTTTGAGATCGTGATTATGGTGCTGAAGGACAAATTCCAGGTGGCTGTAAATGGAAAACATACTCTGCTCTATGGCCACAGGATCG
GCCCAGAGAAAATAGACACTCTGGGCATTTATGGCAAAGTGAATATTCACTCAATTGGTTTTAGCTTCAGCTCGGACTTACAAAGTACCC
AAGCATCTAGTCTGGAACTGACAGAGATAAGTAGAGAAAATCTGGAAGATCTGGAAGTTACTGTAGCTGATCACATTCAAAAGGTCATGA
AACTGAACTTCGAAGCAGCCTGGGATGAGGTAGGGGATGAATTTGAGAAGGAGGAAACGTTCACCTTGTCTACCATCAAGACACTTGAAG
AGGCTGTGGGTAATATTGTGAAGTTCTTGGGAATGCACCCTTGTGAGAGGTCAGACAAAGTGCCGGATAACAAGAACACCCACACGTTGC
TCCTGGCTGGTGTGTTCCGGGGTGGTCATGACATCCTGGTGCGCTCCCGGCTGCTGCTTTTGGACACAGTGACAATGCAGGTGACAGCCA
GAAGTTTGGAGGAGCTGCCAGTAGACATCATCTTGGCATCTGTGGGATAAGAGGCCAGCCTGCATAGGACCTCATACCCTTCCCCAACAC
TACCTGGAAGTTGTGCCTTCCTCATGAAACTGGCAGAAACCCCTTCCCAAGCTTCTGTATTGAAAAACAATTAGGAATCATTGCAGATTT
TTTTTTATTCTGCTCCCACCTCCCACCCGGGACTACTTGCTGGTGACTTTTTTTTTTTTTTTTTTTAAATAGGGGATGATTTTAGCTTGT
CCTAAATCTTGCTGTCCACCCTTCCAGGAAAGGGACATTGTAAATGAATAAAACATTCTCAACTCCTCTTGAATCTATCCCCCAAGAAAC

>In-frame_ENST00000527974_ENST00000314797_TCGA-VR-AA7D_LGALS8_chr1_236705010_+_COPG1_chr3_128993680_length(amino acids)=316AA_start in transcript=89_stop in transcript=1039
MPKILGHTQKRLQSTRSWKRMMLSLNNLQNIIYNPVIPFVGTIPDQLDPGTLIVIRGHVPSDADRFQVDLQNGSSMKPRADVAFHFNPRF
KRAGCIVCNTLINEKWGREEITYDTPFKREKSFEIVIMVLKDKFQVAVNGKHTLLYGHRIGPEKIDTLGIYGKVNIHSIGFSFSSDLQST
QASSLELTEISRENLEDLEVTVADHIQKVMKLNFEAAWDEVGDEFEKEETFTLSTIKTLEEAVGNIVKFLGMHPCERSDKVPDNKNTHTL

--------------------------------------------------------------
>In-frame_ENST00000352231_ENST00000314797_TCGA-VR-AA7D_LGALS8_chr1_236705010_+_COPG1_chr3_128993680_length(transcript)=1438nt_BP=722nt
GATCCTGTAGAACTTCGGAGATTGGGGAAGATAATCGGAAGAGGTAGAAGACACCGTCCATGACACTTCCTGGGGAAGCAGATGTATGTA
TAAGGATGGCCAGTGCCTCAGTTTCAATCCAGGTAACCTTTAAATGAAACTTGCCTAAAATCTTAGGTCATACACAGAAGAGACTCCAAT
CGACAAGAAGCTGGAAAAGAATGATGTTGTCCTTAAACAACCTACAGAATATCATCTATAACCCGGTAATCCCGTTTGTTGGCACCATTC
CTGATCAGCTGGATCCTGGAACTTTGATTGTGATACGTGGGCATGTTCCTAGTGACGCAGACAGATTCCAGGTGGATCTGCAGAATGGCA
GCAGCATGAAACCTCGAGCCGATGTGGCCTTTCATTTCAATCCTCGTTTCAAAAGGGCCGGCTGCATTGTTTGCAATACTTTGATAAATG
AAAAATGGGGACGGGAAGAGATCACCTATGACACGCCTTTCAAAAGAGAAAAGTCTTTTGAGATCGTGATTATGGTGCTGAAGGACAAAT
TCCAGGTGGCTGTAAATGGAAAACATACTCTGCTCTATGGCCACAGGATCGGCCCAGAGAAAATAGACACTCTGGGCATTTATGGCAAAG
TGAATATTCACTCAATTGGTTTTAGCTTCAGCTCGGACTTACAAAGTACCCAAGCATCTAGTCTGGAACTGACAGAGATAAGTAGAGAAA
ATCTGGAAGATCTGGAAGTTACTGTAGCTGATCACATTCAAAAGGTCATGAAACTGAACTTCGAAGCAGCCTGGGATGAGGTAGGGGATG
AATTTGAGAAGGAGGAAACGTTCACCTTGTCTACCATCAAGACACTTGAAGAGGCTGTGGGTAATATTGTGAAGTTCTTGGGAATGCACC
CTTGTGAGAGGTCAGACAAAGTGCCGGATAACAAGAACACCCACACGTTGCTCCTGGCTGGTGTGTTCCGGGGTGGTCATGACATCCTGG
TGCGCTCCCGGCTGCTGCTTTTGGACACAGTGACAATGCAGGTGACAGCCAGAAGTTTGGAGGAGCTGCCAGTAGACATCATCTTGGCAT
CTGTGGGATAAGAGGCCAGCCTGCATAGGACCTCATACCCTTCCCCAACACTACCTGGAAGTTGTGCCTTCCTCATGAAACTGGCAGAAA
CCCCTTCCCAAGCTTCTGTATTGAAAAACAATTAGGAATCATTGCAGATTTTTTTTTATTCTGCTCCCACCTCCCACCCGGGACTACTTG
CTGGTGACTTTTTTTTTTTTTTTTTTTAAATAGGGGATGATTTTAGCTTGTCCTAAATCTTGCTGTCCACCCTTCCAGGAAAGGGACATT

>In-frame_ENST00000352231_ENST00000314797_TCGA-VR-AA7D_LGALS8_chr1_236705010_+_COPG1_chr3_128993680_length(amino acids)=316AA_start in transcript=140_stop in transcript=1090
MPKILGHTQKRLQSTRSWKRMMLSLNNLQNIIYNPVIPFVGTIPDQLDPGTLIVIRGHVPSDADRFQVDLQNGSSMKPRADVAFHFNPRF
KRAGCIVCNTLINEKWGREEITYDTPFKREKSFEIVIMVLKDKFQVAVNGKHTLLYGHRIGPEKIDTLGIYGKVNIHSIGFSFSSDLQST
QASSLELTEISRENLEDLEVTVADHIQKVMKLNFEAAWDEVGDEFEKEETFTLSTIKTLEEAVGNIVKFLGMHPCERSDKVPDNKNTHTL

--------------------------------------------------------------
>In-frame_ENST00000341872_ENST00000314797_TCGA-VR-AA7D_LGALS8_chr1_236705010_+_COPG1_chr3_128993680_length(transcript)=1619nt_BP=903nt
TGGACTTGGATCCGAGGCAGACGAGGAAGCTGAGAAAACCCTGGCGTTGACCCCGTGGACCTGGGCGCCCCGGGAAGGCCAGCGCTTGGT
CCAGGCAGGCGGGGCCTGTGCGGTGACCACCCTGGTCCTGAAAAGTCCCAGCCCCGAGCGCCCTCCCTCCTAGACCTGGAGGCCTGGAAC
AGCCAGCCGCCCACGGACGCCAGAGCCGGGAACCCTGACGGCACTTAGCTGCTGACAAACAACCTGCTCCGTGGAGCGCCTGAAACACCA
GTCTTTGGGGCCAGTGCCTCAGTTTCAATCCAGGTAACCTTTAAATGAAACTTGCCTAAAATCTTAGGTCATACACAGAAGAGACTCCAA
TCGACAAGAAGCTGGAAAAGAATGATGTTGTCCTTAAACAACCTACAGAATATCATCTATAACCCGGTAATCCCGTTTGTTGGCACCATT
CCTGATCAGCTGGATCCTGGAACTTTGATTGTGATACGTGGGCATGTTCCTAGTGACGCAGACAGATTCCAGGTGGATCTGCAGAATGGC
AGCAGCATGAAACCTCGAGCCGATGTGGCCTTTCATTTCAATCCTCGTTTCAAAAGGGCCGGCTGCATTGTTTGCAATACTTTGATAAAT
GAAAAATGGGGACGGGAAGAGATCACCTATGACACGCCTTTCAAAAGAGAAAAGTCTTTTGAGATCGTGATTATGGTGCTGAAGGACAAA
TTCCAGGTGGCTGTAAATGGAAAACATACTCTGCTCTATGGCCACAGGATCGGCCCAGAGAAAATAGACACTCTGGGCATTTATGGCAAA
GTGAATATTCACTCAATTGGTTTTAGCTTCAGCTCGGACTTACAAAGTACCCAAGCATCTAGTCTGGAACTGACAGAGATAAGTAGAGAA
AATCTGGAAGATCTGGAAGTTACTGTAGCTGATCACATTCAAAAGGTCATGAAACTGAACTTCGAAGCAGCCTGGGATGAGGTAGGGGAT
GAATTTGAGAAGGAGGAAACGTTCACCTTGTCTACCATCAAGACACTTGAAGAGGCTGTGGGTAATATTGTGAAGTTCTTGGGAATGCAC
CCTTGTGAGAGGTCAGACAAAGTGCCGGATAACAAGAACACCCACACGTTGCTCCTGGCTGGTGTGTTCCGGGGTGGTCATGACATCCTG
GTGCGCTCCCGGCTGCTGCTTTTGGACACAGTGACAATGCAGGTGACAGCCAGAAGTTTGGAGGAGCTGCCAGTAGACATCATCTTGGCA
TCTGTGGGATAAGAGGCCAGCCTGCATAGGACCTCATACCCTTCCCCAACACTACCTGGAAGTTGTGCCTTCCTCATGAAACTGGCAGAA
ACCCCTTCCCAAGCTTCTGTATTGAAAAACAATTAGGAATCATTGCAGATTTTTTTTTATTCTGCTCCCACCTCCCACCCGGGACTACTT
GCTGGTGACTTTTTTTTTTTTTTTTTTTAAATAGGGGATGATTTTAGCTTGTCCTAAATCTTGCTGTCCACCCTTCCAGGAAAGGGACAT

>In-frame_ENST00000341872_ENST00000314797_TCGA-VR-AA7D_LGALS8_chr1_236705010_+_COPG1_chr3_128993680_length(amino acids)=316AA_start in transcript=321_stop in transcript=1271
MPKILGHTQKRLQSTRSWKRMMLSLNNLQNIIYNPVIPFVGTIPDQLDPGTLIVIRGHVPSDADRFQVDLQNGSSMKPRADVAFHFNPRF
KRAGCIVCNTLINEKWGREEITYDTPFKREKSFEIVIMVLKDKFQVAVNGKHTLLYGHRIGPEKIDTLGIYGKVNIHSIGFSFSSDLQST
QASSLELTEISRENLEDLEVTVADHIQKVMKLNFEAAWDEVGDEFEKEETFTLSTIKTLEEAVGNIVKFLGMHPCERSDKVPDNKNTHTL

--------------------------------------------------------------
>In-frame_ENST00000450372_ENST00000314797_TCGA-VR-AA7D_LGALS8_chr1_236705010_+_COPG1_chr3_128993680_length(transcript)=1619nt_BP=903nt
TGGACTTGGATCCGAGGCAGACGAGGAAGCTGAGAAAACCCTGGCGTTGACCCCGTGGACCTGGGCGCCCCGGGAAGGCCAGCGCTTGGT
CCAGGCAGGCGGGGCCTGTGCGGTGACCACCCTGGTCCTGAAAAGTCCCAGCCCCGAGCGCCCTCCCTCCTAGACCTGGAGGCCTGGAAC
AGCCAGCCGCCCACGGACGCCAGAGCCGGGAACCCTGACGGCACTTAGCTGCTGACAAACAACCTGCTCCGTGGAGCGCCTGAAACACCA
GTCTTTGGGGCCAGTGCCTCAGTTTCAATCCAGGTAACCTTTAAATGAAACTTGCCTAAAATCTTAGGTCATACACAGAAGAGACTCCAA
TCGACAAGAAGCTGGAAAAGAATGATGTTGTCCTTAAACAACCTACAGAATATCATCTATAACCCGGTAATCCCGTTTGTTGGCACCATT
CCTGATCAGCTGGATCCTGGAACTTTGATTGTGATACGTGGGCATGTTCCTAGTGACGCAGACAGATTCCAGGTGGATCTGCAGAATGGC
AGCAGCATGAAACCTCGAGCCGATGTGGCCTTTCATTTCAATCCTCGTTTCAAAAGGGCCGGCTGCATTGTTTGCAATACTTTGATAAAT
GAAAAATGGGGACGGGAAGAGATCACCTATGACACGCCTTTCAAAAGAGAAAAGTCTTTTGAGATCGTGATTATGGTGCTGAAGGACAAA
TTCCAGGTGGCTGTAAATGGAAAACATACTCTGCTCTATGGCCACAGGATCGGCCCAGAGAAAATAGACACTCTGGGCATTTATGGCAAA
GTGAATATTCACTCAATTGGTTTTAGCTTCAGCTCGGACTTACAAAGTACCCAAGCATCTAGTCTGGAACTGACAGAGATAAGTAGAGAA
AATCTGGAAGATCTGGAAGTTACTGTAGCTGATCACATTCAAAAGGTCATGAAACTGAACTTCGAAGCAGCCTGGGATGAGGTAGGGGAT
GAATTTGAGAAGGAGGAAACGTTCACCTTGTCTACCATCAAGACACTTGAAGAGGCTGTGGGTAATATTGTGAAGTTCTTGGGAATGCAC
CCTTGTGAGAGGTCAGACAAAGTGCCGGATAACAAGAACACCCACACGTTGCTCCTGGCTGGTGTGTTCCGGGGTGGTCATGACATCCTG
GTGCGCTCCCGGCTGCTGCTTTTGGACACAGTGACAATGCAGGTGACAGCCAGAAGTTTGGAGGAGCTGCCAGTAGACATCATCTTGGCA
TCTGTGGGATAAGAGGCCAGCCTGCATAGGACCTCATACCCTTCCCCAACACTACCTGGAAGTTGTGCCTTCCTCATGAAACTGGCAGAA
ACCCCTTCCCAAGCTTCTGTATTGAAAAACAATTAGGAATCATTGCAGATTTTTTTTTATTCTGCTCCCACCTCCCACCCGGGACTACTT
GCTGGTGACTTTTTTTTTTTTTTTTTTTAAATAGGGGATGATTTTAGCTTGTCCTAAATCTTGCTGTCCACCCTTCCAGGAAAGGGACAT

>In-frame_ENST00000450372_ENST00000314797_TCGA-VR-AA7D_LGALS8_chr1_236705010_+_COPG1_chr3_128993680_length(amino acids)=316AA_start in transcript=321_stop in transcript=1271
MPKILGHTQKRLQSTRSWKRMMLSLNNLQNIIYNPVIPFVGTIPDQLDPGTLIVIRGHVPSDADRFQVDLQNGSSMKPRADVAFHFNPRF
KRAGCIVCNTLINEKWGREEITYDTPFKREKSFEIVIMVLKDKFQVAVNGKHTLLYGHRIGPEKIDTLGIYGKVNIHSIGFSFSSDLQST
QASSLELTEISRENLEDLEVTVADHIQKVMKLNFEAAWDEVGDEFEKEETFTLSTIKTLEEAVGNIVKFLGMHPCERSDKVPDNKNTHTL

--------------------------------------------------------------
>In-frame_ENST00000366584_ENST00000314797_TCGA-VR-AA7D_LGALS8_chr1_236705010_+_COPG1_chr3_128993680_length(transcript)=1804nt_BP=1088nt
TAGACCTGGAGGCCTGGAACAGCCAGGTGGACGTCGGCCCACCTTTCTTTTCTTTCCTTCCCATTTTCCTACCACCTCCCACCCCACTCC
GCCTTCCGGGCAAAGGCAGCCAGATCCACCCAGGACACATTCTTTGTCCTTATCCCTCTGTGCTCGTCCCACAGCAAGCCAGTCGCGGTC
CAAGGCTCCAGAGGCTGTGCAGGAGGCCGAGCTGGGTGGCGATCAGCGGCGGGTCCCTGTCCAAAACCCAGCAGAGCCGCCAGGGACGCC
CCAGACACAGAAGGCGGGGCGCGGGGAGGGTGGGGAGACCACAGCAGTGAGGCGCGCGAGCCGGGAAGTGAACGAGGACTGACTCCTGTC
GCTTCCCGTAGCCGCCCACGGACGCCAGAGCCGGGAACCCTGACGGCACTTAGCTGCTGACAAACAACCTGCTCCGTGGAGCGCCTGAAA
CACCAGTCTTTGGGGCCAGTGCCTCAGTTTCAATCCAGGTAACCTTTAAATGAAACTTGCCTAAAATCTTAGGTCATACACAGAAGAGAC
TCCAATCGACAAGAAGCTGGAAAAGAATGATGTTGTCCTTAAACAACCTACAGAATATCATCTATAACCCGGTAATCCCGTTTGTTGGCA
CCATTCCTGATCAGCTGGATCCTGGAACTTTGATTGTGATACGTGGGCATGTTCCTAGTGACGCAGACAGATTCCAGGTGGATCTGCAGA
ATGGCAGCAGCATGAAACCTCGAGCCGATGTGGCCTTTCATTTCAATCCTCGTTTCAAAAGGGCCGGCTGCATTGTTTGCAATACTTTGA
TAAATGAAAAATGGGGACGGGAAGAGATCACCTATGACACGCCTTTCAAAAGAGAAAAGTCTTTTGAGATCGTGATTATGGTGCTGAAGG
ACAAATTCCAGGTGGCTGTAAATGGAAAACATACTCTGCTCTATGGCCACAGGATCGGCCCAGAGAAAATAGACACTCTGGGCATTTATG
GCAAAGTGAATATTCACTCAATTGGTTTTAGCTTCAGCTCGGACTTACAAAGTACCCAAGCATCTAGTCTGGAACTGACAGAGATAAGTA
GAGAAAATCTGGAAGATCTGGAAGTTACTGTAGCTGATCACATTCAAAAGGTCATGAAACTGAACTTCGAAGCAGCCTGGGATGAGGTAG
GGGATGAATTTGAGAAGGAGGAAACGTTCACCTTGTCTACCATCAAGACACTTGAAGAGGCTGTGGGTAATATTGTGAAGTTCTTGGGAA
TGCACCCTTGTGAGAGGTCAGACAAAGTGCCGGATAACAAGAACACCCACACGTTGCTCCTGGCTGGTGTGTTCCGGGGTGGTCATGACA
TCCTGGTGCGCTCCCGGCTGCTGCTTTTGGACACAGTGACAATGCAGGTGACAGCCAGAAGTTTGGAGGAGCTGCCAGTAGACATCATCT
TGGCATCTGTGGGATAAGAGGCCAGCCTGCATAGGACCTCATACCCTTCCCCAACACTACCTGGAAGTTGTGCCTTCCTCATGAAACTGG
CAGAAACCCCTTCCCAAGCTTCTGTATTGAAAAACAATTAGGAATCATTGCAGATTTTTTTTTATTCTGCTCCCACCTCCCACCCGGGAC
TACTTGCTGGTGACTTTTTTTTTTTTTTTTTTTAAATAGGGGATGATTTTAGCTTGTCCTAAATCTTGCTGTCCACCCTTCCAGGAAAGG
GACATTGTAAATGAATAAAACATTCTCAACTCCTCTTGAATCTATCCCCCAAGAAACCATCTTATCCCTGTAATAAATCAGCATGTATTT

>In-frame_ENST00000366584_ENST00000314797_TCGA-VR-AA7D_LGALS8_chr1_236705010_+_COPG1_chr3_128993680_length(amino acids)=316AA_start in transcript=506_stop in transcript=1456
MPKILGHTQKRLQSTRSWKRMMLSLNNLQNIIYNPVIPFVGTIPDQLDPGTLIVIRGHVPSDADRFQVDLQNGSSMKPRADVAFHFNPRF
KRAGCIVCNTLINEKWGREEITYDTPFKREKSFEIVIMVLKDKFQVAVNGKHTLLYGHRIGPEKIDTLGIYGKVNIHSIGFSFSSDLQST
QASSLELTEISRENLEDLEVTVADHIQKVMKLNFEAAWDEVGDEFEKEETFTLSTIKTLEEAVGNIVKFLGMHPCERSDKVPDNKNTHTL

--------------------------------------------------------------
>In-frame_ENST00000323938_ENST00000314797_TCGA-VR-AA7D_LGALS8_chr1_236705010_+_COPG1_chr3_128993680_length(transcript)=1298nt_BP=582nt
AACCTGCTCCGTGGAGCGCCTGAAACACCAGTCTTTGGGGCCAGTGCCTCAGTTTCAATCCAGGTAACCTTTAAATGAAACTTGCCTAAA
ATCTTAGGTCATACACAGAAGAGACTCCAATCGACAAGAAGCTGGAAAAGAATGATGTTGTCCTTAAACAACCTACAGAATATCATCTAT
AACCCGGTAATCCCGTTTGTTGGCACCATTCCTGATCAGCTGGATCCTGGAACTTTGATTGTGATACGTGGGCATGTTCCTAGTGACGCA
GACAGGGCCGGCTGCATTGTTTGCAATACTTTGATAAATGAAAAATGGGGACGGGAAGAGATCACCTATGACACGCCTTTCAAAAGAGAA
AAGTCTTTTGAGATCGTGATTATGGTGCTGAAGGACAAATTCCAGGTGGCTGTAAATGGAAAACATACTCTGCTCTATGGCCACAGGATC
GGCCCAGAGAAAATAGACACTCTGGGCATTTATGGCAAAGTGAATATTCACTCAATTGGTTTTAGCTTCAGCTCGGACTTACAAAGTACC
CAAGCATCTAGTCTGGAACTGACAGAGATAAGTAGAGAAAATCTGGAAGATCTGGAAGTTACTGTAGCTGATCACATTCAAAAGGTCATG
AAACTGAACTTCGAAGCAGCCTGGGATGAGGTAGGGGATGAATTTGAGAAGGAGGAAACGTTCACCTTGTCTACCATCAAGACACTTGAA
GAGGCTGTGGGTAATATTGTGAAGTTCTTGGGAATGCACCCTTGTGAGAGGTCAGACAAAGTGCCGGATAACAAGAACACCCACACGTTG
CTCCTGGCTGGTGTGTTCCGGGGTGGTCATGACATCCTGGTGCGCTCCCGGCTGCTGCTTTTGGACACAGTGACAATGCAGGTGACAGCC
AGAAGTTTGGAGGAGCTGCCAGTAGACATCATCTTGGCATCTGTGGGATAAGAGGCCAGCCTGCATAGGACCTCATACCCTTCCCCAACA
CTACCTGGAAGTTGTGCCTTCCTCATGAAACTGGCAGAAACCCCTTCCCAAGCTTCTGTATTGAAAAACAATTAGGAATCATTGCAGATT
TTTTTTTATTCTGCTCCCACCTCCCACCCGGGACTACTTGCTGGTGACTTTTTTTTTTTTTTTTTTTAAATAGGGGATGATTTTAGCTTG
TCCTAAATCTTGCTGTCCACCCTTCCAGGAAAGGGACATTGTAAATGAATAAAACATTCTCAACTCCTCTTGAATCTATCCCCCAAGAAA

>In-frame_ENST00000323938_ENST00000314797_TCGA-VR-AA7D_LGALS8_chr1_236705010_+_COPG1_chr3_128993680_length(amino acids)=289AA_start in transcript=81_stop in transcript=950
MPKILGHTQKRLQSTRSWKRMMLSLNNLQNIIYNPVIPFVGTIPDQLDPGTLIVIRGHVPSDADRAGCIVCNTLINEKWGREEITYDTPF
KREKSFEIVIMVLKDKFQVAVNGKHTLLYGHRIGPEKIDTLGIYGKVNIHSIGFSFSSDLQSTQASSLELTEISRENLEDLEVTVADHIQ
KVMKLNFEAAWDEVGDEFEKEETFTLSTIKTLEEAVGNIVKFLGMHPCERSDKVPDNKNTHTLLLAGVFRGGHDILVRSRLLLLDTVTMQ

--------------------------------------------------------------
>In-frame_ENST00000526634_ENST00000314797_TCGA-VR-AA7D_LGALS8_chr1_236705010_+_COPG1_chr3_128993680_length(transcript)=1501nt_BP=785nt
GACTTCCTTTGACCGTACGTGAAACTTAAGTGATGGCTGCTTGTGATGCATACGAAGTGTTCATGCTGGCGGGACCTGTCCCTGGGGATA
CTTCGGGGGTTGCGTGATTTAATGCAAGCAGATGGCTTAAATTGGGTCACTGGCTTGTTATTATACATGTGGCCAGTGCCTCAGTTTCAA
TCCAGGTAACCTTTAAATGAAACTTGCCTAAAATCTTAGGTCATACACAGAAGAGACTCCAATCGACAAGAAGCTGGAAAAGAATGATGT
TGTCCTTAAACAACCTACAGAATATCATCTATAACCCGGTAATCCCGTTTGTTGGCACCATTCCTGATCAGCTGGATCCTGGAACTTTGA
TTGTGATACGTGGGCATGTTCCTAGTGACGCAGACAGATTCCAGGTGGATCTGCAGAATGGCAGCAGCATGAAACCTCGAGCCGATGTGG
CCTTTCATTTCAATCCTCGTTTCAAAAGGGCCGGCTGCATTGTTTGCAATACTTTGATAAATGAAAAATGGGGACGGGAAGAGATCACCT
ATGACACGCCTTTCAAAAGAGAAAAGTCTTTTGAGATCGTGATTATGGTGCTGAAGGACAAATTCCAGGTGGCTGTAAATGGAAAACATA
CTCTGCTCTATGGCCACAGGATCGGCCCAGAGAAAATAGACACTCTGGGCATTTATGGCAAAGTGAATATTCACTCAATTGGTTTTAGCT
TCAGCTCGGACTTACAAAGTACCCAAGCATCTAGTCTGGAACTGACAGAGATAAGTAGAGAAAATCTGGAAGATCTGGAAGTTACTGTAG
CTGATCACATTCAAAAGGTCATGAAACTGAACTTCGAAGCAGCCTGGGATGAGGTAGGGGATGAATTTGAGAAGGAGGAAACGTTCACCT
TGTCTACCATCAAGACACTTGAAGAGGCTGTGGGTAATATTGTGAAGTTCTTGGGAATGCACCCTTGTGAGAGGTCAGACAAAGTGCCGG
ATAACAAGAACACCCACACGTTGCTCCTGGCTGGTGTGTTCCGGGGTGGTCATGACATCCTGGTGCGCTCCCGGCTGCTGCTTTTGGACA
CAGTGACAATGCAGGTGACAGCCAGAAGTTTGGAGGAGCTGCCAGTAGACATCATCTTGGCATCTGTGGGATAAGAGGCCAGCCTGCATA
GGACCTCATACCCTTCCCCAACACTACCTGGAAGTTGTGCCTTCCTCATGAAACTGGCAGAAACCCCTTCCCAAGCTTCTGTATTGAAAA
ACAATTAGGAATCATTGCAGATTTTTTTTTATTCTGCTCCCACCTCCCACCCGGGACTACTTGCTGGTGACTTTTTTTTTTTTTTTTTTT
AAATAGGGGATGATTTTAGCTTGTCCTAAATCTTGCTGTCCACCCTTCCAGGAAAGGGACATTGTAAATGAATAAAACATTCTCAACTCC

>In-frame_ENST00000526634_ENST00000314797_TCGA-VR-AA7D_LGALS8_chr1_236705010_+_COPG1_chr3_128993680_length(amino acids)=316AA_start in transcript=203_stop in transcript=1153
MPKILGHTQKRLQSTRSWKRMMLSLNNLQNIIYNPVIPFVGTIPDQLDPGTLIVIRGHVPSDADRFQVDLQNGSSMKPRADVAFHFNPRF
KRAGCIVCNTLINEKWGREEITYDTPFKREKSFEIVIMVLKDKFQVAVNGKHTLLYGHRIGPEKIDTLGIYGKVNIHSIGFSFSSDLQST
QASSLELTEISRENLEDLEVTVADHIQKVMKLNFEAAWDEVGDEFEKEETFTLSTIKTLEEAVGNIVKFLGMHPCERSDKVPDNKNTHTL

--------------------------------------------------------------

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Fusion Gene PPI Analysis for LGALS8-COPG1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
TgeneCOPG1chr1:236705010chr3:128993680ENST000003147972024609_874752.0875.0ZNF289/ARFGAP2


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for LGALS8-COPG1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for LGALS8-COPG1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneCOPG1C0345967Malignant mesothelioma1CTD_human