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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:LRRC27-BIVM (FusionGDB2 ID:49649)

Fusion Gene Summary for LRRC27-BIVM

check button Fusion gene summary
Fusion gene informationFusion gene name: LRRC27-BIVM
Fusion gene ID: 49649
HgeneTgene
Gene symbol

LRRC27

BIVM

Gene ID

80313

54841

Gene nameleucine rich repeat containing 27basic, immunoglobulin-like variable motif containing
Synonyms--
Cytomap

10q26.3

13q33.1

Type of geneprotein-codingprotein-coding
Descriptionleucine-rich repeat-containing protein 27testicular tissue protein Li 108basic immunoglobulin-like variable motif-containing protein
Modification date2020031320200313
UniProtAcc

Q9C0I9

Q86UB2

Ensembl transtripts involved in fusion geneENST00000368615, ENST00000392638, 
ENST00000344079, ENST00000356571, 
ENST00000368614, ENST00000368613, 
ENST00000368612, ENST00000368610, 
ENST00000432555, ENST00000475747, 
ENST00000257336, ENST00000448849, 
ENST00000419638, ENST00000491929, 
Fusion gene scores* DoF score2 X 2 X 2=83 X 3 X 3=27
# samples 23
** MAII scorelog2(2/8*10)=1.32192809488736log2(3/27*10)=0.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: LRRC27 [Title/Abstract] AND BIVM [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointLRRC27(134158154)-BIVM(103473387), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across LRRC27 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across BIVM (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-CD-A486-01ALRRC27chr10

134158154

+BIVMchr13

103473387

+


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Fusion Gene ORF analysis for LRRC27-BIVM

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000368615ENST00000257336LRRC27chr10

134158154

+BIVMchr13

103473387

+
5CDS-5UTRENST00000368615ENST00000448849LRRC27chr10

134158154

+BIVMchr13

103473387

+
5CDS-5UTRENST00000368615ENST00000419638LRRC27chr10

134158154

+BIVMchr13

103473387

+
5CDS-intronENST00000368615ENST00000491929LRRC27chr10

134158154

+BIVMchr13

103473387

+
Frame-shiftENST00000392638ENST00000257336LRRC27chr10

134158154

+BIVMchr13

103473387

+
5CDS-5UTRENST00000392638ENST00000448849LRRC27chr10

134158154

+BIVMchr13

103473387

+
5CDS-5UTRENST00000392638ENST00000419638LRRC27chr10

134158154

+BIVMchr13

103473387

+
5CDS-intronENST00000392638ENST00000491929LRRC27chr10

134158154

+BIVMchr13

103473387

+
Frame-shiftENST00000344079ENST00000257336LRRC27chr10

134158154

+BIVMchr13

103473387

+
5CDS-5UTRENST00000344079ENST00000448849LRRC27chr10

134158154

+BIVMchr13

103473387

+
5CDS-5UTRENST00000344079ENST00000419638LRRC27chr10

134158154

+BIVMchr13

103473387

+
5CDS-intronENST00000344079ENST00000491929LRRC27chr10

134158154

+BIVMchr13

103473387

+
In-frameENST00000356571ENST00000257336LRRC27chr10

134158154

+BIVMchr13

103473387

+
5CDS-5UTRENST00000356571ENST00000448849LRRC27chr10

134158154

+BIVMchr13

103473387

+
5CDS-5UTRENST00000356571ENST00000419638LRRC27chr10

134158154

+BIVMchr13

103473387

+
5CDS-intronENST00000356571ENST00000491929LRRC27chr10

134158154

+BIVMchr13

103473387

+
Frame-shiftENST00000368614ENST00000257336LRRC27chr10

134158154

+BIVMchr13

103473387

+
5CDS-5UTRENST00000368614ENST00000448849LRRC27chr10

134158154

+BIVMchr13

103473387

+
5CDS-5UTRENST00000368614ENST00000419638LRRC27chr10

134158154

+BIVMchr13

103473387

+
5CDS-intronENST00000368614ENST00000491929LRRC27chr10

134158154

+BIVMchr13

103473387

+
Frame-shiftENST00000368613ENST00000257336LRRC27chr10

134158154

+BIVMchr13

103473387

+
5CDS-5UTRENST00000368613ENST00000448849LRRC27chr10

134158154

+BIVMchr13

103473387

+
5CDS-5UTRENST00000368613ENST00000419638LRRC27chr10

134158154

+BIVMchr13

103473387

+
5CDS-intronENST00000368613ENST00000491929LRRC27chr10

134158154

+BIVMchr13

103473387

+
Frame-shiftENST00000368612ENST00000257336LRRC27chr10

134158154

+BIVMchr13

103473387

+
5CDS-5UTRENST00000368612ENST00000448849LRRC27chr10

134158154

+BIVMchr13

103473387

+
5CDS-5UTRENST00000368612ENST00000419638LRRC27chr10

134158154

+BIVMchr13

103473387

+
5CDS-intronENST00000368612ENST00000491929LRRC27chr10

134158154

+BIVMchr13

103473387

+
Frame-shiftENST00000368610ENST00000257336LRRC27chr10

134158154

+BIVMchr13

103473387

+
5CDS-5UTRENST00000368610ENST00000448849LRRC27chr10

134158154

+BIVMchr13

103473387

+
5CDS-5UTRENST00000368610ENST00000419638LRRC27chr10

134158154

+BIVMchr13

103473387

+
5CDS-intronENST00000368610ENST00000491929LRRC27chr10

134158154

+BIVMchr13

103473387

+
Frame-shiftENST00000432555ENST00000257336LRRC27chr10

134158154

+BIVMchr13

103473387

+
5CDS-5UTRENST00000432555ENST00000448849LRRC27chr10

134158154

+BIVMchr13

103473387

+
5CDS-5UTRENST00000432555ENST00000419638LRRC27chr10

134158154

+BIVMchr13

103473387

+
5CDS-intronENST00000432555ENST00000491929LRRC27chr10

134158154

+BIVMchr13

103473387

+
intron-3CDSENST00000475747ENST00000257336LRRC27chr10

134158154

+BIVMchr13

103473387

+
intron-5UTRENST00000475747ENST00000448849LRRC27chr10

134158154

+BIVMchr13

103473387

+
intron-5UTRENST00000475747ENST00000419638LRRC27chr10

134158154

+BIVMchr13

103473387

+
intron-intronENST00000475747ENST00000491929LRRC27chr10

134158154

+BIVMchr13

103473387

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000356571LRRC27chr10134158154+ENST00000257336BIVMchr13103473387+31796061121512466

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000356571ENST00000257336LRRC27chr10134158154+BIVMchr13103473387+0.0044507560.9955492

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Fusion Genomic Features for LRRC27-BIVM


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
LRRC27chr10134158154+BIVMchr13103473386+0.047106240.9528938
LRRC27chr10134158154+BIVMchr13103473386+0.047106240.9528938

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for LRRC27-BIVM


check button Go to

FGviewer for the breakpoints of chr10:134158154-chr13:103473387

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
LRRC27

Q9C0I9

BIVM

Q86UB2


check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneLRRC27chr10:134158154chr13:103473387ENST00000344079+59115_136184.33333333333334513.0RepeatNote=LRR 4
HgeneLRRC27chr10:134158154chr13:103473387ENST00000344079+59138_159184.33333333333334513.0RepeatNote=LRR 5
HgeneLRRC27chr10:134158154chr13:103473387ENST00000344079+5946_67184.33333333333334513.0RepeatNote=LRR 1
HgeneLRRC27chr10:134158154chr13:103473387ENST00000344079+5968_89184.33333333333334513.0RepeatNote=LRR 2
HgeneLRRC27chr10:134158154chr13:103473387ENST00000344079+5992_113184.33333333333334513.0RepeatNote=LRR 3
HgeneLRRC27chr10:134158154chr13:103473387ENST00000368610+41046_67122.33333333333333469.0RepeatNote=LRR 1
HgeneLRRC27chr10:134158154chr13:103473387ENST00000368610+41068_89122.33333333333333469.0RepeatNote=LRR 2
HgeneLRRC27chr10:134158154chr13:103473387ENST00000368610+41092_113122.33333333333333469.0RepeatNote=LRR 3
HgeneLRRC27chr10:134158154chr13:103473387ENST00000368612+51146_67122.33333333333333469.0RepeatNote=LRR 1
HgeneLRRC27chr10:134158154chr13:103473387ENST00000368612+51168_89122.33333333333333469.0RepeatNote=LRR 2
HgeneLRRC27chr10:134158154chr13:103473387ENST00000368612+51192_113122.33333333333333469.0RepeatNote=LRR 3
HgeneLRRC27chr10:134158154chr13:103473387ENST00000368613+511115_136184.33333333333334531.0RepeatNote=LRR 4
HgeneLRRC27chr10:134158154chr13:103473387ENST00000368613+511138_159184.33333333333334531.0RepeatNote=LRR 5
HgeneLRRC27chr10:134158154chr13:103473387ENST00000368613+51146_67184.33333333333334531.0RepeatNote=LRR 1
HgeneLRRC27chr10:134158154chr13:103473387ENST00000368613+51168_89184.33333333333334531.0RepeatNote=LRR 2
HgeneLRRC27chr10:134158154chr13:103473387ENST00000368613+51192_113184.33333333333334531.0RepeatNote=LRR 3
HgeneLRRC27chr10:134158154chr13:103473387ENST00000368614+511115_136184.33333333333334531.0RepeatNote=LRR 4
HgeneLRRC27chr10:134158154chr13:103473387ENST00000368614+511138_159184.33333333333334531.0RepeatNote=LRR 5
HgeneLRRC27chr10:134158154chr13:103473387ENST00000368614+51146_67184.33333333333334531.0RepeatNote=LRR 1
HgeneLRRC27chr10:134158154chr13:103473387ENST00000368614+51168_89184.33333333333334531.0RepeatNote=LRR 2
HgeneLRRC27chr10:134158154chr13:103473387ENST00000368614+51192_113184.33333333333334531.0RepeatNote=LRR 3
HgeneLRRC27chr10:134158154chr13:103473387ENST00000368615+58115_136184.33333333333334384.0RepeatNote=LRR 4
HgeneLRRC27chr10:134158154chr13:103473387ENST00000368615+58138_159184.33333333333334384.0RepeatNote=LRR 5
HgeneLRRC27chr10:134158154chr13:103473387ENST00000368615+5846_67184.33333333333334384.0RepeatNote=LRR 1
HgeneLRRC27chr10:134158154chr13:103473387ENST00000368615+5868_89184.33333333333334384.0RepeatNote=LRR 2
HgeneLRRC27chr10:134158154chr13:103473387ENST00000368615+5892_113184.33333333333334384.0RepeatNote=LRR 3
HgeneLRRC27chr10:134158154chr13:103473387ENST00000392638+512115_136184.333333333333342447.0RepeatNote=LRR 4
HgeneLRRC27chr10:134158154chr13:103473387ENST00000392638+512138_159184.333333333333342447.0RepeatNote=LRR 5
HgeneLRRC27chr10:134158154chr13:103473387ENST00000392638+51246_67184.333333333333342447.0RepeatNote=LRR 1
HgeneLRRC27chr10:134158154chr13:103473387ENST00000392638+51268_89184.333333333333342447.0RepeatNote=LRR 2
HgeneLRRC27chr10:134158154chr13:103473387ENST00000392638+51292_113184.333333333333342447.0RepeatNote=LRR 3

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneLRRC27chr10:134158154chr13:103473387ENST00000344079+59327_385184.33333333333334513.0Coiled coilOntology_term=ECO:0000255
HgeneLRRC27chr10:134158154chr13:103473387ENST00000368610+410327_385122.33333333333333469.0Coiled coilOntology_term=ECO:0000255
HgeneLRRC27chr10:134158154chr13:103473387ENST00000368612+511327_385122.33333333333333469.0Coiled coilOntology_term=ECO:0000255
HgeneLRRC27chr10:134158154chr13:103473387ENST00000368613+511327_385184.33333333333334531.0Coiled coilOntology_term=ECO:0000255
HgeneLRRC27chr10:134158154chr13:103473387ENST00000368614+511327_385184.33333333333334531.0Coiled coilOntology_term=ECO:0000255
HgeneLRRC27chr10:134158154chr13:103473387ENST00000368615+58327_385184.33333333333334384.0Coiled coilOntology_term=ECO:0000255
HgeneLRRC27chr10:134158154chr13:103473387ENST00000392638+512327_385184.333333333333342447.0Coiled coilOntology_term=ECO:0000255
HgeneLRRC27chr10:134158154chr13:103473387ENST00000368610+410115_136122.33333333333333469.0RepeatNote=LRR 4
HgeneLRRC27chr10:134158154chr13:103473387ENST00000368610+410138_159122.33333333333333469.0RepeatNote=LRR 5
HgeneLRRC27chr10:134158154chr13:103473387ENST00000368612+511115_136122.33333333333333469.0RepeatNote=LRR 4
HgeneLRRC27chr10:134158154chr13:103473387ENST00000368612+511138_159122.33333333333333469.0RepeatNote=LRR 5


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Fusion Gene Sequence for LRRC27-BIVM


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000356571_ENST00000257336_TCGA-CD-A486-01A_LRRC27_chr10_134158154_+_BIVM_chr13_103473387_length(transcript)=3179nt_BP=606nt
ATTGTCGGGCTGCTGCTCTCAGCGGCGGGGCTCGCCAGCGCTTCAGTGGGCGGGGACGCGGCAGGTGACTCCAGACCAAGGAGGATGAGC
TGCTGTCCCTGGAAGAGAACGGATGGAGGGAAGCAGCTCCTACGAAGTTCCCTCTGTGGCTGCTGCTGATCTGGAGGAGGGTGCTGGTCA
GACTAGGAGCTTGCCTGCCACCCCCTCCAAAGATGTTCACAAGGGTGTTGGAGGCATCATCTTTTCCTCCTCACCGATTTTAGACTTGAG
TGAAAGTGGTCTGTGCCGTTTGGAGGAGGTCTTTAGAATCCCCAGCCTTCAACAATTGCATCTGCAAAGGAATGCCCTGTGTGTGATTCC
TCAAGATTTCTTTCAGTTGCTTCCGAACCTGACTTGGCTGGACCTCCGGTACAATAGAATTAAAGCGCTTCCTTCTGGGATTGGAGCTCA
CCAGGAGCGTAACCACGCTGAAAGCACTGAACCTAAGACACTGCCCTCTGGAATTCCCTCCTCAGCTCGTTGTGCAGAAGGGATTGGTGG
CTATCCAGCGCTTCCTGCGGATGTGGGCAGTAGAACACTCTCTCCCCAGAAATCCAACTTCTCAAGGTACTGCATAAGCCGACCACAGTA
TAAGACTTCTTGTGGCATCTCTTCATTAATTTCTTGTTGGAATTTCTTATACAGCACAATGGGAGCTGGAAACCTTCCACCTATTACCCA
AGAAGAAGCTTTACATATTCTGGGCTTTCAACCTCCATTTGAAGATATTAGGTTTGGTCCTTTCACGGGGAATACAACACTTATGAGGTG
GTTTAGACAAATTAATGACCACTTCCATGTAAAAGGATGCTCTTATGTTCTATATAAGCCTCATGGGAAGAATAAAACAGCAGGAGAAAC
TGCTTCAGGGGCCCTGTCAAAGTTAACCCGTGGATTGAAAGATGAATCGCTGGCTTATATCTATCATTGCCAAAATCATTATTTTTGTCC
AATTGGCTTCGAAGCAACCCCTGTTAAAGCTAATAAAGCATTCAGCAGGGGACCTCTCTCACCACAGGAAGTTGAATATTGGATCTTAAT
TGGAGAATCAAGTAGAAAACATCCTGCCATTCACTGTAAAAAATGGGCAGATATTGTTACTGATCTAAACACTCAAAATCCAGAATACCT
GGATATCCGGCACTTAGAGAGGGGACTGCAGTATAGAAAAACAAAGAAGGTTGGGGGAAATTTGCATTGCATCATAGCATTCCAGAGACT
TAACTGGCAAAGATTTGGCCTTTGGAACTTTCCATTTGGAACCATTAGACAAGAATCACAACCTCCAACACATGCCCAGGGAATTGCCAA
ATCTGAGAGTGAAGACAATATTTCCAAGAAGCAGCATGGGCGTCTGGGCCGGTCTTTCAGTGCTAGTTTCCATCAGGACTCGGCATGGAA
AAAGATGTCTAGTATCCATGAGAGAAGGAACAGTGGTTACCAGGGTTACAGTGATTACGATGGGAATGATTGACTATGCTTGCTACTGAA
CAGCTGGCATTATATATGAAACTGCTATATACAGGACTGTATAAAGACAGTAGAAGATTTTAGTAAGCCTACATTAAATAGGAGCAGATC
TTGTGGTATAAAAAATAACCTTGTAGTTCTCCAGATACTAAGCTTGTATATGATTATGGTGGGTGATTTCAGATATATAAGCAGATAAGC
ACAGATTATTGTCCTTTCAAGTTAAGAGTATATAATCTGGACAGAAAATTTCACAAAATTCAATAAAATTACAACTGTTGTCTAAATAAG
TGAAACACAAATTCACTTAATAGCATCAAGATTTGAAATACTTAAGCATGAAGTGACTTTTATAATGACTCGATCCCTAGACATTTGTTA
CAGATAGTTTTATGCCTAAGACCAAGATGTAAAGTACCATCTGCCCTTAAAAAAAATTGGGGCTGTCAATTTCTAGTTTTCACTCATGGT
TAACACGCATTTAAAATTATTTCATGAGTCTAGTAGTTCTTTGATTTATAGCAGGATCTTGCTTGCCTCATTTGTTTCCTGGTTATGTTC
TTAGGATTCTGACTAAGAGGCAAAAGAGAAAAGACTCAAGAAACTGATCCTGGAGATCGAGACCATCCTGGCTAACATGGTGAAACCCCG
TCTCTACTAAACATACAAAAAATTAGCCGGGTGTAGTGGTGGGCACCTGTAGTCCTAGCTACTCGAGAGGCTGAGGCAGGAGAATGGCGT
GAACCCGGGAGGTGGAGCTTGCAGTGAGCGGAGATCGCGCCACTGCACTCCAGCCTGGGCGACAGGGCAAGACTCTGTCTCAAAAAAAAA
AAAAAAAAAAAAGACGGATCCTTTTTTTTGGTGCAAATGGGTGACTTAGTGCATTGATTCAGATTTTTAAAATTTCTTGATGTGGTTTGT
AATAATCAAATATTGACAAGAACCTTAGGTCTCGAAAGACTTTTATAAGTCTAGATGACGTTTGCCTTAGGGGTAAAGTAAAAGAACAAT
TGGCACCTTAAGTTTCTATACCCAAGGTTATCTGTGAAATGAGATCTCCTGATATTTGATTGCTTTCTCAGTATGGAGTCATATGTTGAT
AACAGTACTGAAGATGCATAAGAAATGCCCAAGTCACTCAGAGGACAACTACCCATATTCCAGACTCTGAGCTGTTTCCTTTTTAAAAAT
CATATAGACAATTAGCTGTTTGAAGTGAGTATTAAATATTTCAGAAGTGTGAATTTCATGTATTTGAGCTCCTCTAGTTGCTGTTGGTTT
TTCTTCTGCTGCCAACCTGTGACTCACAAATGACTAGGATCTCTTGTTCTTTAATTTTAGGGTCTTGTTCCAGGACTCAAATCAGTAACT
TGGTGATTACAAGGTGCTGAATGTGTTGGTAACCATATCGCAATACACCTCAAGGAAAAGGTTCAGATTTTTATTTTTAAAATATTTTCA
TTTTTTTCTTGAATTTTATATCCGTTTGTTCACTCGTACATGCCTAGCCTACAGAAGGGGATATATATTATGAAATGGTCATTTTTCTGA
AGAGAATATTTTGCTTGAAATGCAAAGGACTGAAAGAGATTTGTAGGTTGTTGATTTTGTTACTTCATACTGGAACTTTTAAAAAGATTT

>In-frame_ENST00000356571_ENST00000257336_TCGA-CD-A486-01A_LRRC27_chr10_134158154_+_BIVM_chr13_103473387_length(amino acids)=466AA_start in transcript=112_stop in transcript=1512
MEGSSSYEVPSVAAADLEEGAGQTRSLPATPSKDVHKGVGGIIFSSSPILDLSESGLCRLEEVFRIPSLQQLHLQRNALCVIPQDFFQLL
PNLTWLDLRYNRIKALPSGIGAHQERNHAESTEPKTLPSGIPSSARCAEGIGGYPALPADVGSRTLSPQKSNFSRYCISRPQYKTSCGIS
SLISCWNFLYSTMGAGNLPPITQEEALHILGFQPPFEDIRFGPFTGNTTLMRWFRQINDHFHVKGCSYVLYKPHGKNKTAGETASGALSK
LTRGLKDESLAYIYHCQNHYFCPIGFEATPVKANKAFSRGPLSPQEVEYWILIGESSRKHPAIHCKKWADIVTDLNTQNPEYLDIRHLER
GLQYRKTKKVGGNLHCIIAFQRLNWQRFGLWNFPFGTIRQESQPPTHAQGIAKSESEDNISKKQHGRLGRSFSASFHQDSAWKKMSSIHE

--------------------------------------------------------------

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Fusion Gene PPI Analysis for LRRC27-BIVM


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for LRRC27-BIVM


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for LRRC27-BIVM


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource