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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:MAN1A2-TTF2 (FusionGDB2 ID:50815)

Fusion Gene Summary for MAN1A2-TTF2

check button Fusion gene summary
Fusion gene informationFusion gene name: MAN1A2-TTF2
Fusion gene ID: 50815
HgeneTgene
Gene symbol

MAN1A2

TTF2

Gene ID

10905

8458

Gene namemannosidase alpha class 1A member 2transcription termination factor 2
SynonymsMAN1BHuF2|ZGRF6
Cytomap

1p12

1p13.1

Type of geneprotein-codingprotein-coding
Descriptionmannosyl-oligosaccharide 1,2-alpha-mannosidase IBalpha-1,2-mannosidase IBalpha1,2-mannosidaseprocessing alpha-1,2-mannosidase IBtranscription termination factor 2F2RNA polymerase II termination factorhuman factor 2lodestar homologlodestar proteintranscription release factor 2transcription termination factor, RNA polymerase IIzinc finger, GRF-type containing 6
Modification date2020031320200313
UniProtAcc

O60476

.
Ensembl transtripts involved in fusion geneENST00000356554, ENST00000482811, 
ENST00000369466, ENST00000480701, 
Fusion gene scores* DoF score12 X 11 X 7=9245 X 8 X 6=240
# samples 2110
** MAII scorelog2(21/924*10)=-2.13750352374993
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(10/240*10)=-1.26303440583379
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: MAN1A2 [Title/Abstract] AND TTF2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointMAN1A2(117963271)-TTF2(117639973), # samples:2
MAN1A2(118003234)-TTF2(117641455), # samples:2
Anticipated loss of major functional domain due to fusion event.MAN1A2-TTF2 seems lost the major protein functional domain in Hgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
MAN1A2-TTF2 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
MAN1A2-TTF2 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across MAN1A2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across TTF2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4OVTCGA-13-0760MAN1A2chr1

117963271

+TTF2chr1

117622189

+
ChimerDB4BRCATCGA-BH-A18Q-01AMAN1A2chr1

117984947

+TTF2chr1

117616283

+
ChimerDB4BRCATCGA-B6-A0I1-01AMAN1A2chr1

117963271

+TTF2chr1

117639973

+
ChimerDB4OVTCGA-13-0760-01AMAN1A2chr1

117963271

+TTF2chr1

117622190

+
ChimerDB4UCECTCGA-AJ-A3QS-01AMAN1A2chr1

118003234

+TTF2chr1

117641455

+
ChimerDB4UCECTCGA-A5-A2K4-01AMAN1A2chr1

117957453

-TTF2chr1

117629039

+
ChimerDB4UCECTCGA-AJ-A3QS-01AMAN1A2chr1

118003234

-TTF2chr1

117641455

+
ChimerDB4BRCATCGA-B6-A0I1-01AMAN1A2chr1

117963271

-TTF2chr1

117639973

+


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Fusion Gene ORF analysis for MAN1A2-TTF2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000356554ENST00000369466MAN1A2chr1

117963271

+TTF2chr1

117622189

+
5CDS-intronENST00000356554ENST00000480701MAN1A2chr1

117963271

+TTF2chr1

117622189

+
intron-3CDSENST00000482811ENST00000369466MAN1A2chr1

117963271

+TTF2chr1

117622189

+
intron-intronENST00000482811ENST00000480701MAN1A2chr1

117963271

+TTF2chr1

117622189

+
In-frameENST00000356554ENST00000369466MAN1A2chr1

117984947

+TTF2chr1

117616283

+
5CDS-intronENST00000356554ENST00000480701MAN1A2chr1

117984947

+TTF2chr1

117616283

+
intron-3CDSENST00000482811ENST00000369466MAN1A2chr1

117984947

+TTF2chr1

117616283

+
intron-intronENST00000482811ENST00000480701MAN1A2chr1

117984947

+TTF2chr1

117616283

+
In-frameENST00000356554ENST00000369466MAN1A2chr1

117963271

+TTF2chr1

117639973

+
5CDS-intronENST00000356554ENST00000480701MAN1A2chr1

117963271

+TTF2chr1

117639973

+
intron-3CDSENST00000482811ENST00000369466MAN1A2chr1

117963271

+TTF2chr1

117639973

+
intron-intronENST00000482811ENST00000480701MAN1A2chr1

117963271

+TTF2chr1

117639973

+
In-frameENST00000356554ENST00000369466MAN1A2chr1

117963271

+TTF2chr1

117622190

+
5CDS-intronENST00000356554ENST00000480701MAN1A2chr1

117963271

+TTF2chr1

117622190

+
intron-3CDSENST00000482811ENST00000369466MAN1A2chr1

117963271

+TTF2chr1

117622190

+
intron-intronENST00000482811ENST00000480701MAN1A2chr1

117963271

+TTF2chr1

117622190

+
Frame-shiftENST00000356554ENST00000369466MAN1A2chr1

118003234

+TTF2chr1

117641455

+
5CDS-3UTRENST00000356554ENST00000480701MAN1A2chr1

118003234

+TTF2chr1

117641455

+
intron-3CDSENST00000482811ENST00000369466MAN1A2chr1

118003234

+TTF2chr1

117641455

+
intron-3UTRENST00000482811ENST00000480701MAN1A2chr1

118003234

+TTF2chr1

117641455

+
Frame-shiftENST00000356554ENST00000369466MAN1A2chr1

117957453

-TTF2chr1

117629039

+
5CDS-intronENST00000356554ENST00000480701MAN1A2chr1

117957453

-TTF2chr1

117629039

+
3UTR-3CDSENST00000482811ENST00000369466MAN1A2chr1

117957453

-TTF2chr1

117629039

+
3UTR-intronENST00000482811ENST00000480701MAN1A2chr1

117957453

-TTF2chr1

117629039

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000356554MAN1A2chr1117963271+ENST00000369466TTF2chr1117622189+930715907353377880
ENST00000356554MAN1A2chr1117984947+ENST00000369466TTF2chr1117616283+10885168573549551406
ENST00000356554MAN1A2chr1117963271+ENST00000369466TTF2chr1117639973+782215907351892385
ENST00000356554MAN1A2chr1117963271+ENST00000369466TTF2chr1117622190+930715907353377880

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000356554ENST00000369466MAN1A2chr1117963271+TTF2chr1117622189+0.0008607840.9991392
ENST00000356554ENST00000369466MAN1A2chr1117984947+TTF2chr1117616283+0.0012450740.998755
ENST00000356554ENST00000369466MAN1A2chr1117963271+TTF2chr1117639973+0.0008010650.999199
ENST00000356554ENST00000369466MAN1A2chr1117963271+TTF2chr1117622190+0.0008607840.9991392

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Fusion Genomic Features for MAN1A2-TTF2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for MAN1A2-TTF2


check button Go to

FGviewer for the breakpoints of chr1:117963271-chr1:117622189

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
MAN1A2

O60476

.
FUNCTION: Involved in the maturation of Asn-linked oligosaccharides. Progressively trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2).FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneMAN1A2chr1:117963271chr1:117622189ENST00000356554+5132_36285.0642.0Topological domainCytoplasmic
HgeneMAN1A2chr1:117963271chr1:117622190ENST00000356554+5132_36285.0642.0Topological domainCytoplasmic
HgeneMAN1A2chr1:117963271chr1:117639973ENST00000356554+5132_36285.0642.0Topological domainCytoplasmic
HgeneMAN1A2chr1:117984947chr1:117616283ENST00000356554+6132_36316.6666666666667642.0Topological domainCytoplasmic
HgeneMAN1A2chr1:117963271chr1:117622189ENST00000356554+51337_57285.0642.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
HgeneMAN1A2chr1:117963271chr1:117622190ENST00000356554+51337_57285.0642.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
HgeneMAN1A2chr1:117963271chr1:117639973ENST00000356554+51337_57285.0642.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
HgeneMAN1A2chr1:117984947chr1:117616283ENST00000356554+61337_57316.6666666666667642.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
TgeneTTF2chr1:117963271chr1:117622189ENST00000369466723583_786567.01163.0DomainHelicase ATP-binding
TgeneTTF2chr1:117963271chr1:117622189ENST00000369466723995_1157567.01163.0DomainHelicase C-terminal
TgeneTTF2chr1:117963271chr1:117622190ENST00000369466723583_786567.01163.0DomainHelicase ATP-binding
TgeneTTF2chr1:117963271chr1:117622190ENST00000369466723995_1157567.01163.0DomainHelicase C-terminal
TgeneTTF2chr1:117984947chr1:117616283ENST00000369466223583_78672.666666666666671163.0DomainHelicase ATP-binding
TgeneTTF2chr1:117984947chr1:117616283ENST00000369466223995_115772.666666666666671163.0DomainHelicase C-terminal
TgeneTTF2chr1:117963271chr1:117622189ENST00000369466723737_740567.01163.0MotifNote=DEAH box
TgeneTTF2chr1:117963271chr1:117622190ENST00000369466723737_740567.01163.0MotifNote=DEAH box
TgeneTTF2chr1:117984947chr1:117616283ENST00000369466223737_74072.666666666666671163.0MotifNote=DEAH box
TgeneTTF2chr1:117963271chr1:117622189ENST00000369466723596_603567.01163.0Nucleotide bindingATP
TgeneTTF2chr1:117963271chr1:117622190ENST00000369466723596_603567.01163.0Nucleotide bindingATP
TgeneTTF2chr1:117984947chr1:117616283ENST00000369466223596_60372.666666666666671163.0Nucleotide bindingATP

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneMAN1A2chr1:117963271chr1:117622189ENST00000356554+51358_641285.0642.0Topological domainLumenal
HgeneMAN1A2chr1:117963271chr1:117622190ENST00000356554+51358_641285.0642.0Topological domainLumenal
HgeneMAN1A2chr1:117963271chr1:117639973ENST00000356554+51358_641285.0642.0Topological domainLumenal
HgeneMAN1A2chr1:117984947chr1:117616283ENST00000356554+61358_641316.6666666666667642.0Topological domainLumenal
TgeneTTF2chr1:117963271chr1:117639973ENST000003694661923583_7861062.01163.0DomainHelicase ATP-binding
TgeneTTF2chr1:117963271chr1:117639973ENST000003694661923995_11571062.01163.0DomainHelicase C-terminal
TgeneTTF2chr1:117963271chr1:117639973ENST000003694661923737_7401062.01163.0MotifNote=DEAH box
TgeneTTF2chr1:117963271chr1:117639973ENST000003694661923596_6031062.01163.0Nucleotide bindingATP
TgeneTTF2chr1:117963271chr1:117622189ENST000003694667235_39567.01163.0Zinc fingerNote=GRF-type
TgeneTTF2chr1:117963271chr1:117622190ENST000003694667235_39567.01163.0Zinc fingerNote=GRF-type
TgeneTTF2chr1:117963271chr1:117639973ENST0000036946619235_391062.01163.0Zinc fingerNote=GRF-type
TgeneTTF2chr1:117984947chr1:117616283ENST000003694662235_3972.666666666666671163.0Zinc fingerNote=GRF-type


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Fusion Gene Sequence for MAN1A2-TTF2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000356554_ENST00000369466_TCGA-13-0760_MAN1A2_chr1_117963271_+_TTF2_chr1_117622189_length(transcript)=9307nt_BP=1590nt
AGACCCGTGCGGTAGCAACAGCGGCGGCGGCCGCGGCGGCTGGCCGGACTCAGGTGTTTCGGACGCTATTGCCCTTCGCGCCAGCCGTCG
AGTGGGCAGCAGCGGGACTCAGCCGGGCGCCAGGTTCCTGCCAGGCAGCGCCGGGAAGCGCGGGCGGCCGAGAACTCCTTCCTGCTACTT
CGCCCAGCGCCGCTGCTTCGGCTTCCCAGCGAAGTGGGAGACCTTCCTCCCTGTTTGCAGACGTCCGTGGGAGACCCTTATTTTTTCCAC
CGCTAAGGTTAAGAGATTCTGGAATAGAAGCGTCGAAGGAGATCAAGTGAACCTTCTACAACTCCTCGGATGTCGCCAGTCTCCCTTTCG
GGGCGGAAGACTACGTTTGAGCATCTCACTGAGGTGCAGGAATGGAAGAACCCACCTTGCAGCTTTTCTGCAGTGTGGCTTGCCTGATCT
ACCCCTAGGAATGAAGAGGAGGCTTGTAATAATCCGATGAAGTACAGATGTTGAAGAGGATATCGCAGGACCTAAACTTGTGATCGTTTG
GGGGAGGTCACACACGTTTCTGAGTGGGAATGGATGGGCGTGAATGACGTGCCCTCTTAAAAAGCACAACAGTCCTTTAAGAGGAGCAAA
ATTGAGTTTTCCCATTTTGGCCAAGATTTTGAAGACAGTTCAATGTATTCTACATTTGACATAAGATGAGAACTTTCTAAAGTATTCTCT
CCAAGAGCGTAAACGATGACTACCCCAGCCCTGCTGCCCCTCTCTGGACGTAGGATACCACCTCTGAACCTGGGGCCGCCTTCCTTCCCA
CATCACAGGGCTACCTTGAGACTTTCTGAGAAGTTTATTCTTCTCCTTATTCTTAGTGCCTTCATCACTCTGTGTTTTGGGGCATTCTTT
TTCCTTCCAGACTCTTCAAAACACAAACGCTTTGATTTGGGTTTAGAAGATGTGTTAATTCCACATGTAGATGCCGGTAAAGGGGCTAAA
AACCCCGGAGTCTTCCTGATCCATGGACCCGATGAACATAGACACAGGGAAGAGGAAGAACGTCTGAGAAATAAAATTCGAGCTGATCAT
GAGAAGGCCTTGGAAGAAGCAAAAGAAAAATTAAGAAAGTCAAGAGAGGAAATTCGAGCAGAAATTCAGACAGAGAAAAATAAGGTAGTC
CAAGAAATGAAGATAAAAGAGAACAAGCCACTGCCACCAGTCCCTATTCCCAACCTTGTAGGAATACGTGGTGGAGACCCAGAAGATAAT
GACATAAGAGAGAAAAGGGAAAAAATTAAAGAGATGATGAAACATGCTTGGGATAACTATAGGACATATGGGTGGGGACATAATGAACTC
AGACCTATTGCAAGGAAAGGACACTCCCCTAACATATTTGGAAGTTCACAAATGGGTGCTACCATAGTAGATGCTTTGGATACCCTTTAT
ATCATGGGACTTCATGATGAATTCCTAGATGGGCAAAGATGGATTGAAGACAACCTTGATTTCAGTGTGAATTCAGAGGTGTCTGTGTTT
GAAGTCAACATTCGATTTATTGGAGGCCTACTTGCAGCATATTACCTATCAGGAGAGGAGGTCCCTTTGCTACTACACCAGAAGCAGGCA
TTGGCTTGGTTACTATGGCGAGAAAGTCAGAAGCCACAAGGAGGAATTCTGGCAGATGATATGGGCTTAGGAAAAACCCTGACAATGATT
GCGCTCATCCTGACCCAGAAGAATCAAGAGAAAAAGGAAGAAAAGGAGAAAAGCACAGCTTTGACGTGGCTCTCCAAAGATGACTCTTGT
GACTTTACTTCCCATGGAACACTAATCATCTGTCCTGCCTCCCTGATCCATCATTGGAAAAATGAGGTGGAGAAACGGGTGAACAGCAAC
AAACTAAGAGTCTATCTCTACCATGGGCCAAACCGGGATTCACGTGCCAGAGTCCTCTCTACATATGACATCGTGATCACTACCTATAGC
CTCGTGGCCAAGGAGATTCCCACAAACAAGCAAGAGGCAGAGATCCCAGGTGCAAACCTCAATGTGGAGGGCACCTCAACACCTTTGCTT
CGAATAGCCTGGGCTCGAATCATATTGGATGAAGCTCACAATGTTAAGAATCCCCGAGTGCAGACTTCCATAGCTGTGTGTAAGCTACAA
GCCTGTGCCCGTTGGGCTGTCACTGGAACCCCCATTCAAAACAACTTATTGGATATGTATTCGCTGCTGAAGTTTCTCCGTTGCTCTCCA
TTTGATGAGTTCAATCTGTGGAGGAGTCAGGTTGACAATGGCTCAAAGAAAGGAGGAGAACGGTTAAGTATTTTAACCAAGAGCCTTTTG
CTGAGGAGAACAAAAGACCAGCTGGACTCTACTGGCAGACCTTTGGTGATACTGCCCCAGCGTAAATTTCAGTTGCACCATTTAAAGCTT
TCTGAAGATGAAGAGACTGTTTACAATGTGTTTTTTGCAAGATCAAGGTCAGCTCTGCAATCCTATCTAAAAAGACATGAAAGTAGAGGC
AACCAATCTGGAAGAAGCCCTAATAATCCATTCAGTAGAGTGGCACTGGAGTTTGGGTCTGAGGAGCCTAGACACTCGGAGGCAGCAGAC
TCACCGAGATCCAGCACCGTCCACATACTGTCCCAGTTGCTGAGACTCCGCCAGTGTTGCTGTCATCTTTCTTTACTGAAGTCGGCCCTG
GATCCAATGGAACTGAAGGGTGAAGGTCTTGTCCTTTCCCTGGAAGAACAGCTCAGTGCTTTGACCTTGTCAGAACTCCGTGACTCAGAG
CCATCTTCCACTGTTTCCCTTAACGGCACCTTCTTCAAGATGGAGCTTTTTGAAGGCATGCGAGAGAGCACCAAGATTTCATCTCTGTTG
GCAGAATTGGAGGCAATTCAAAGAAATTCAGCATCCCAAAAGAGTGTCATTGTCTCTCAGTGGACCAACATGCTGAAAGTTGTAGCATTG
CACCTGAAGAAGCATGGACTGACTTATGCCACCATCGATGGCTCTGTCAATCCCAAGCAGAGAATGGACTTGGTAGAGGCATTTAACCAC
TCCAGAGGCCCTCAGGTAATGCTAATCTCTCTCTTGGCCGGAGGTGTTGGTCTAAACCTGACTGGAGGAAATCACCTCTTTCTTTTGGAC
ATGCACTGGAATCCATCACTTGAAGATCAAGCTTGTGACCGAATTTACCGAGTAGGGCAGCAGAAAGATGTTGTCATACACAGATTTGTT
TGTGAGGGAACAGTAGAAGAAAAGATCTTACAGCTCCAAGAAAAAAAGAAAGATTTGGCCAAACAAGTTCTATCAGGGTCTGGAGAATCT
GTCACCAAGCTCACCTTGGCTGACCTCAGAGTCCTTTTTGGCATCTAACCTCCTGTGGATAAGGGCTCAGAATAGCACCATTGCTGGTTT
GTATTAGGATCTGGGAATAACAACCTAACCATGAGCCTTGAACTCTGTTCTTTGCATTTCAATTTCACCGTCAAGCCTTTCACCTTCCTC
AAAATGAGGCATAATCTTATCCCCAGAATTGAGGAGGGGTTGTGTTAACCAATTAGTTAACCAATTATGTTAATAATTTATTTAATGAGT
GGTATGGAAACCAATTGATTTTTTTAGATAAAAGAATATGTTTTAGAGTTGGATGATTTTGGAAAACAACTCTGGCAGAATTGTATATAA
GCTTCAGTAAAGTTCAAAAAGCGGGCCAGGTGTGGTGGCTCATGCCTGTAATCCCGACACTTTGGGAGGCCAAGGCAGGAGGATGGCTTG
AAGCCAGTAGTTCAAGACCAGCCTGGGCAACATAGTAAGACCCCATCTCTATGAAGAATAAAAAAATGAGCTAGGCGTGGTAGTGCACAC
CTGTAGTCCTAGCTACTTGGGAGGCTGAGGCAGGAGGATCCCTTGAGTCCAGGAGGTTGAGGCTGCAGTGAGCTGTGATTGTGCCACTGT
TTTCCAGCCTGGGCAATACAGTGAGACCCTGTCTCAAAAAAAGGAAAAAAAAGCTCAAAAAGTTCTGTGTTGCCTTTCTCTTCTTAGCTG
ATGATGGGAGAACCAGTTACTACCTTCTCTAACACAGGCTCCATCCTATCTCTTCATCTCTTCTTGCCAGTGATGTTGCACCTGTAACCA
TCTTTTTATGGGTGGAGCAGAGAGTCAATCCCTGCAGCCACCCTGCAGCCAGCCATCTCTGCAGTTCTCTCAGTGCAGGCAGTTCTTCCT
CTCAGGCTGAAGATCAAGGAGATGCTTTGTACATGAACAGATGCTGAGTATCTGTTATCATTGTATTGTTTAGTGTCAGTGTATCATTTA
GTATTTGTATCACTGTACCATTTAGTGTTGTATATCACTCAGTCATTTAATATTGGTTATCACCATACAGTTTAATATTTGTATCATTTG
GTTCATTGTATCGTTTAGTATTTCTATTATAACATTTCTATTTGTAGTATTTGTATAATATTTGTGTCATTTTTAATAGTATTTGTATTT
TTACAAATTTGCAGTATTTGTAGCATTTAGTATCATTGTTTCATTTAGTATTTGGTACAATCTAATAAATACTAATCCAGTCCAATACTA
ATCCAATCCAATACTAATAATACTATTGGTACAATCCAATACTAATAATACTATTGGTACAATCCAATACTAATAATACTAACAGTAGTA
TTGATACAATCTAATAAATAATGTGTTTGACAGTGTAGCAGAAATAATGCTATGTGTTCACCAAACCCACTTCCTTTTCCTCCCGGGCAC
CCAGAGAGACTGTATTTCCCAGTTTTTGCTGCAGTTTGACGGGGTCCATATCAATGGACTGTGGAGAGAAGCGATTGATGTAAGTCACTT
CTAGGTGGCCCTCTACCACTTTCCAAAAGATCATTCATGCTGTTTCTTCCCTCCTCAGCCTATGGGATGCAAAGGAACTGATGGAAGATT
ACAAGGCCCTAGGGAAGGTGAAGCCACTAGCTCAGCAGTTCTTAGCCTAGTTTTTGGCCATCAGCCCTTCTATTAGACTAGTGAAGCCTC
AGTCCCAGGATGGCTCCCCATGTACACTTCCCTCCTCGCCCCAGCTCACCTACACTGGACTATGACATGATCAAGGAATCTTTTTTTTTA
AGCTACTGAGATTTCTGTGTTGTTTACATAGCAGTTTGTACCCTAAACAAACACTTGAGATTTTATACTTCAGGAAACTATTCAGATTTC
CTTCTCATTAGCAATTGTTCCAAAAACACTTACTCTGCTAATTTCTGCTAGAAAGAATCACAGTTCTTCTAACACAGAAACATTTCTGTC
CCTTGAGTTGGGAAACAAGACCCTATGTTAACCCAGTCAGAGTGTGGACTGAGGCATTCGGAGCCTATTTAAGCAGAAGTTTTCTATAAG
GACAAGATTTAAAGGCTTACAAAGGTAAAGACAATGGCCTGGTGGGAAGAATTCTAGTCTAGAACGTTTGAGATTTGACTCTAGTTCTAG
GTTCATCTTAGCTGGGTGTGTAACGTTGAAAAAATTGGCCGGGTGCAGTGGCTCAGGCCTGTCATCCCAGCACTTTGGGAGGCCGAGGCA
GACGGATCACGAGGTCAAGAGATCAAGACCATCTTGGCCAACATGGTGAAACCCCGTCTCTACTAAAAATACAAAAATTAGCTGAGCGTG
GTGGCGTGCGCCTGTAGTCCCAGCTACTGGGGAGGATAAGGCAGGAGAATCGCTTGAACCTGGGAGGTGGAGGTTGCAGTGAGCTGAGAT
CGCGCCATTGCACTCCAGCCTGGTGACAGAGCGAGACTCCGTCTCAAAAAAAAAAAAAAAAAAAAAGAGAGAGAAAAAAATCCTTACTTT
CTCTACACTCTGATTTCCTCATTTGTAAGGTGGGCAGTTTTCAGAACTTAGCAGCAATAAGGTTTCTGATAAAATCAAGAAGCAAAGGAA
GTAACATTGCCTTTTTGAAGTTTTGCTATAAGATTGACATACCAAGGTAAAGATTGAGTCACCTGAGAAGCAGTGGCTCCCAGGCCAGCA
AGAATGTACAAACCTGGCTCTGCCATTTGCTGATTGATATTAGGCAAGTTGCAGATTCCTTGGACATCTCAATCCTTTCATCTGTAAAAT
GTGTGGATTAGCATGTATCTCATGCTCCACTGGGAATTTCATAGCAAATATATATACTACAACATGGTTGACCAGATAGATCAGTAATGT
CAACTAGAAGGTATTAGATGAACATTGTCAGTCTCCAATCAAGCATTGTTTAGGGGAGAGGAATTCTTTCAGGTTCAAGCATTCTGGCTT
TTAGTTTGGAGAGGGATGCAGGGATTGTAACTTAAAATCTTCAGATATTGAGGCCATTGACAAGTAATCTACTGTAAGGTAGATGCCTCC
TGGTATTTTAAAACAGCTTTTCTAATTTCTCATGTTATTGTACATAAGCAAAGCAACCTAGTTATGTCTTGGGTAGGTGTTCTTATAGCC
GTGAGATGCTACTGACTTGAGGTGGATGCAGAAAAAAATGGAACCACTGCCTTAATGGGATGGAATATACTAAACATGCATTCTTAAATC
CTAGTGCTGGGATGGATTACATGAATTACATTGTGGAGCTGCATATGTGTCTCCCCTCTTCCCTCCCTGGGGGTTAGGCTGGGTTTGTTT
GGTTTTTTTTGTTTTGTCCTCATGAGGCTTAGCATCTAAGGGAGACAGGCATGAATTAACAGAAGTGGCATTCTGGTATCTGTCTCAGCC
TCATATTCATTTTAGTGTAAATCAGTTTCGTCAAGTCTAGGTATGACAAGGTGGGTCTTTGCACCTTCTAGCGATGGGCAGCATCCCACA
ACACAGTGGTCTAATTGAGGTGCTGCACTATGAGTCCTGCCTGTGTTAACCAGCCTTCCTTCATGTCACAATACTGCTGCTGGATTTGCT
TTTTACATCTGCCTATTGCACCTGACTTGGGCATGGATGATATGAGGTAATAAATGCTTTGAAAACCATGAAGGGCCACACAAGTGCTAG
TGTTATTGCTGTGGGACAAGGTCTGGGAATATGAGAACCAGCAGCAGCATGGGTGCAGCTGAGAACCAGATGGTGAACATCTGTCTCCAA
AGTGCAACATTCCTGAGCACCGGATTTATAAGGCATTTCTTACTCGACAGAATTGACTTCATGGAAGGTATGTAGTTTGACTTTGCCTTA
GCCATGTTGATCAAATAGGAGTATTGTGCATGCCGCAGCTAGACAGAGTCCTGGGCCCTTTAAAAACCTTGTCAGTGACTCCCATTGCAG
GCCCAGCGCAGTGGTTCACACCTGTAATCCCAGCATTTGGGAGGCTGAGGCAGGCAGATCACTTGAGGCCAAGAGTTCGAGACCAGACTG
GCCAACATGGCAAAACCTCCTCTCTACTAAAAATACAAAAGTTAGCCAGGCGTGATGTTGGGTGCCTGTAATTGCAGCTACTCGGGAGGC
TGAGGCAGGAGAATCACTTGAATCCAGGAGGCGGAGGTTACAGTGAGCTGAGATCATACCACTGCACTCCAGCCTGGGCCACAGAGAAAG
AACGGTGATTCTTTCTAGCAGAAATTAGCAGAGTAAGTGTTTTTGGAACAATTGCTAATGAAAAGAAGGAAAAACAGAAAAAAAAAATTT
TCTGTTTATGGGAGGTGACTTATTTCTCTATCAATCCTGTGAGTGATTTAGCATGGCAATTCATGAACACTGAGTTGTTTCCTTGCTCTG
ATTGTCTGTTGCTCAATGAAATGGCTTTTAGCAGGGCTCAAAGGTGAAGCCAGATTCTCCTGCACTAATAGGATAAGCATGGAGACACCA
GTGTTCAGTGTGGCCTCTGGTTGTCTGAAATTTTGCTGTCAACTCTAATACCTTGAAAGAATTAGGTTTCCAAAGTGGGATATTGTGCTG
CTGTTTGTGATATAGCATCTAGACTTAGGAAAGGGCAGGAACAATTTAAAAGCACATCTGTAGGCACAAAGAGAATTATAATAGAAATTC
AGAATTCCTAGGCATATGACCTAGACTAAAATGTCTTCATAACTACAAATGAAATCAGGGTCATTTATAGTACAAACTACCACAGAAGTC
AGTAGTTAGGGGATGGAGATAGATATGAAAAAAAAAAAAAGCAAACCCAGCCTAACTCCCAGGGAGGGAAGAGGGGCGACAGATATGCAG
CTACACAATGTTTTTACTATCTTGAGTTCTTTTTACCCAGATTCCATAGCTAAATCCAGATGTATTAATAGGTAGAGACTACTTCAGAAA
GGATGAGACTATTTTCTTGCTTAATTATCCACACAGTAATTCAGAAATGTATATTGAACACTTTTTATATGCCAGGCACTGCTGGGCACT
GGAAATATAAAAGTAAGCAAAAATGAAAAACTATCCTGTCCTCCTGAGGCTTAGCATCTAAGGGAGACAGGCATTAGTCAACCCCGTGTG
GCTGTGAATCAGCCATGATGCTGAGTGCTACAAGAGAGGACTGTGCGGCTGGGAGGGCTTATAACAGGATTTGACCTAGTTAGGGAAGAT
CTGAGGAAGTGATGAAAGAATGGAAATCAATATGTAAGAGCTCACAAGTCAGAGTGAGATGTTTCTTCCTATACTGCCTGCTTCTAATGA
GCATCCACTTCATTGAACCACCTCTTCATTGAGCCAAACCTACCATACAGGGATACATTCTCTGGAGGAAAGTTGAGCAACTATTGCATT
TGGGACATTAGAGTATGGGTGGGCTGACAGGTATGTGTATGTTTATTATCCAAGACAGCCAAGGTGTTTATCCTGTTACAACATCCCAGA
GGACAGAGGCTCTTATTTGTGACTCTTTTTTCTTACCTGTAACACCAGAGGCATAACGTACATCATAATGCTGCATCTTGTTGACGCTTC
AATGCTCACAATTCAAAGGTGATTTCTGAAGCACTTTGTTACACTGGGGACAGCTCCTAAATCCTCCCACTCTTTTTTTGCCTCACCTTG
GAGTCTTGGGCTCTGTTGATCACTGACTCTGCCAGGTCTTTCAGCAGGCAAGACAGCTCAGTTAAATTGAGTTTGGACTCCACTGTAGTG
CATGCATGAGACAGCACCCCCAATCCCCAACACCCACACACAAACTTTAAATATTTGTAACAGAATTGTTACCATTAATATTGCTTAAAG
GCTAACACATTAGCCAGAACCTAGATGTCTTCTGGAAATTTTTTATTGCAATGTTACTTCATCTACATAAAGTTGTCCAATCACTGAAAC

>In-frame_ENST00000356554_ENST00000369466_TCGA-13-0760_MAN1A2_chr1_117963271_+_TTF2_chr1_117622189_length(amino acids)=880AA_start in transcript=735_stop in transcript=3377
MTTPALLPLSGRRIPPLNLGPPSFPHHRATLRLSEKFILLLILSAFITLCFGAFFFLPDSSKHKRFDLGLEDVLIPHVDAGKGAKNPGVF
LIHGPDEHRHREEEERLRNKIRADHEKALEEAKEKLRKSREEIRAEIQTEKNKVVQEMKIKENKPLPPVPIPNLVGIRGGDPEDNDIREK
REKIKEMMKHAWDNYRTYGWGHNELRPIARKGHSPNIFGSSQMGATIVDALDTLYIMGLHDEFLDGQRWIEDNLDFSVNSEVSVFEVNIR
FIGGLLAAYYLSGEEVPLLLHQKQALAWLLWRESQKPQGGILADDMGLGKTLTMIALILTQKNQEKKEEKEKSTALTWLSKDDSCDFTSH
GTLIICPASLIHHWKNEVEKRVNSNKLRVYLYHGPNRDSRARVLSTYDIVITTYSLVAKEIPTNKQEAEIPGANLNVEGTSTPLLRIAWA
RIILDEAHNVKNPRVQTSIAVCKLQACARWAVTGTPIQNNLLDMYSLLKFLRCSPFDEFNLWRSQVDNGSKKGGERLSILTKSLLLRRTK
DQLDSTGRPLVILPQRKFQLHHLKLSEDEETVYNVFFARSRSALQSYLKRHESRGNQSGRSPNNPFSRVALEFGSEEPRHSEAADSPRSS
TVHILSQLLRLRQCCCHLSLLKSALDPMELKGEGLVLSLEEQLSALTLSELRDSEPSSTVSLNGTFFKMELFEGMRESTKISSLLAELEA
IQRNSASQKSVIVSQWTNMLKVVALHLKKHGLTYATIDGSVNPKQRMDLVEAFNHSRGPQVMLISLLAGGVGLNLTGGNHLFLLDMHWNP

--------------------------------------------------------------
>In-frame_ENST00000356554_ENST00000369466_TCGA-BH-A18Q-01A_MAN1A2_chr1_117984947_+_TTF2_chr1_117616283_length(transcript)=10885nt_BP=1685nt
AGACCCGTGCGGTAGCAACAGCGGCGGCGGCCGCGGCGGCTGGCCGGACTCAGGTGTTTCGGACGCTATTGCCCTTCGCGCCAGCCGTCG
AGTGGGCAGCAGCGGGACTCAGCCGGGCGCCAGGTTCCTGCCAGGCAGCGCCGGGAAGCGCGGGCGGCCGAGAACTCCTTCCTGCTACTT
CGCCCAGCGCCGCTGCTTCGGCTTCCCAGCGAAGTGGGAGACCTTCCTCCCTGTTTGCAGACGTCCGTGGGAGACCCTTATTTTTTCCAC
CGCTAAGGTTAAGAGATTCTGGAATAGAAGCGTCGAAGGAGATCAAGTGAACCTTCTACAACTCCTCGGATGTCGCCAGTCTCCCTTTCG
GGGCGGAAGACTACGTTTGAGCATCTCACTGAGGTGCAGGAATGGAAGAACCCACCTTGCAGCTTTTCTGCAGTGTGGCTTGCCTGATCT
ACCCCTAGGAATGAAGAGGAGGCTTGTAATAATCCGATGAAGTACAGATGTTGAAGAGGATATCGCAGGACCTAAACTTGTGATCGTTTG
GGGGAGGTCACACACGTTTCTGAGTGGGAATGGATGGGCGTGAATGACGTGCCCTCTTAAAAAGCACAACAGTCCTTTAAGAGGAGCAAA
ATTGAGTTTTCCCATTTTGGCCAAGATTTTGAAGACAGTTCAATGTATTCTACATTTGACATAAGATGAGAACTTTCTAAAGTATTCTCT
CCAAGAGCGTAAACGATGACTACCCCAGCCCTGCTGCCCCTCTCTGGACGTAGGATACCACCTCTGAACCTGGGGCCGCCTTCCTTCCCA
CATCACAGGGCTACCTTGAGACTTTCTGAGAAGTTTATTCTTCTCCTTATTCTTAGTGCCTTCATCACTCTGTGTTTTGGGGCATTCTTT
TTCCTTCCAGACTCTTCAAAACACAAACGCTTTGATTTGGGTTTAGAAGATGTGTTAATTCCACATGTAGATGCCGGTAAAGGGGCTAAA
AACCCCGGAGTCTTCCTGATCCATGGACCCGATGAACATAGACACAGGGAAGAGGAAGAACGTCTGAGAAATAAAATTCGAGCTGATCAT
GAGAAGGCCTTGGAAGAAGCAAAAGAAAAATTAAGAAAGTCAAGAGAGGAAATTCGAGCAGAAATTCAGACAGAGAAAAATAAGGTAGTC
CAAGAAATGAAGATAAAAGAGAACAAGCCACTGCCACCAGTCCCTATTCCCAACCTTGTAGGAATACGTGGTGGAGACCCAGAAGATAAT
GACATAAGAGAGAAAAGGGAAAAAATTAAAGAGATGATGAAACATGCTTGGGATAACTATAGGACATATGGGTGGGGACATAATGAACTC
AGACCTATTGCAAGGAAAGGACACTCCCCTAACATATTTGGAAGTTCACAAATGGGTGCTACCATAGTAGATGCTTTGGATACCCTTTAT
ATCATGGGACTTCATGATGAATTCCTAGATGGGCAAAGATGGATTGAAGACAACCTTGATTTCAGTGTGAATTCAGAGGTGTCTGTGTTT
GAAGTCAACATTCGATTTATTGGAGGCCTACTTGCAGCATATTACCTATCAGGAGAGGAGATATTCAAGATTAAAGCAGTGCAATTGGCT
GAGAAACTCCTTCCTGCCTTTAACACACCTACTGGGATTCCTTGGGCAATGGTGAATTTGAAAAGATTGTTCTTCCGATGCATTAGAAGT
AAGGCAGAGGGGAAACGCTGGTGTGGAAGTATTCCATGGCAGGATCCTGATTCCAAAGAACATTCTGTATCCAATAAGTCTCAGCATGCA
TCTGAGACATTTCATCATTCTTCCAACTGGCTGAGAAATCCATTCAAGGTACTTGACAAGAATCAAGAACCAGCTCTCTGGAAACAGCTC
ATCAAAGGTGAAGGTGAGGAAAAGAAGGCTGATAAGAAGCAAAGAGAAAAGGGAGATCAGCTTTTCGATCAAAAGAAAGAACAGAAGCCT
GAAATGATGGAGAAAGACCTCTCATCTGGCCTGGTACCAAAGAAAAAACAATCTGTAGTTCAAGAGAAGAAGCAAGAAGAGGGAGCAGAG
ATTCAGTGTGAGGCAGAGACTGGAGGCACACACAAAAGAGACTTTTCTGAAATTAAATCTCAACAGTGCCAAGGTAATGAGCTTACAAGA
CCATCTGCATCTTCTCAGGAGAAATCAAGTGGTAAGAGTCAAGATGTCCAAAGAGAATCAGAACCTCTGAGAGAAAAGGTTACCCAGCTT
TTGCCTCAAAATGTTCACAGTCACAACTCAATAAGCAAGCCCCAGAAAGGGGGACCCCTCAACAAGGAGTACACGAACTGGGAGGCTAAA
GAAACAAAGGCAAAGGATGGCCCTAGCATACAGGCCACCCAGAAAAGCCTGCCTCAGGGGCATTTCCAAGAGCGGCCGGAGACCCACAGT
GTGCCTGCTCCTGGAGGACCAGCGGCTCAGGCTGCACCAGCAGCACCAGGGCTTTCCCTGGGTGAGGGCCGTGAAGCTGCCACAAGCAGT
GACGACGAGGAGGAAGATGATGTTGTTTTTGTTTCCTCTAAGCCTGGGAGCCCCCTACTCTTTGACTCGACTCTGGACTTAGAGACGAAG
GAAAACCTCCAATTCCCTGATCGAAGTGTGCAAAGAAAGGTGTCTCCTGCCTCAGGTGTTTCCAAGAAGGTAGAACCCTCAGACCCAGTA
GCCCGGCGTGTCTACCTTACAACACAACTGAAACAAAAGAAGAGCACACTGGCATCAGTGAACATCCAGGCTCTTCCAGACAAGGGTCAG
AAGTTGATCAAACAAATCCAGGAGCTGGAGGAAGTACTCAGTGGTCTTACCCTTTCCCCAGAGCAAGGAACTAATGAGAAGAGTAACAGT
CAAGTACCACAGCAGAGTCACTTCACCAAAACTACCACTGGCCCTCCCCACCTGGTGCCTCCCCAACCCCTTCCTCGTCGTGGTACCCAA
CCTGTGGGTTCTCTAGAACTAAAGTCTGCCTGCCAGGTGACTGCTGGAGGATCCAGTCAGTGCTATCGAGGCCATACAAACCAAGATCAC
GTTCATGCAGTGTGGAAAATCACAAGTGAAGCCATCGGTCAACTGCATCGCTCACTTGAGTCATGTCCTGGTGAGACGGTTGTGGCAGAA
GATCCCGCCGGGCTGAAGGTCCCTTTGCTACTACACCAGAAGCAGGCATTGGCTTGGTTACTATGGCGAGAAAGTCAGAAGCCACAAGGA
GGAATTCTGGCAGATGATATGGGCTTAGGAAAAACCCTGACAATGATTGCGCTCATCCTGACCCAGAAGAATCAAGAGAAAAAGGAAGAA
AAGGAGAAAAGCACAGCTTTGACGTGGCTCTCCAAAGATGACTCTTGTGACTTTACTTCCCATGGAACACTAATCATCTGTCCTGCCTCC
CTGATCCATCATTGGAAAAATGAGGTGGAGAAACGGGTGAACAGCAACAAACTAAGAGTCTATCTCTACCATGGGCCAAACCGGGATTCA
CGTGCCAGAGTCCTCTCTACATATGACATCGTGATCACTACCTATAGCCTCGTGGCCAAGGAGATTCCCACAAACAAGCAAGAGGCAGAG
ATCCCAGGTGCAAACCTCAATGTGGAGGGCACCTCAACACCTTTGCTTCGAATAGCCTGGGCTCGAATCATATTGGATGAAGCTCACAAT
GTTAAGAATCCCCGAGTGCAGACTTCCATAGCTGTGTGTAAGCTACAAGCCTGTGCCCGTTGGGCTGTCACTGGAACCCCCATTCAAAAC
AACTTATTGGATATGTATTCGCTGCTGAAGTTTCTCCGTTGCTCTCCATTTGATGAGTTCAATCTGTGGAGGAGTCAGGTTGACAATGGC
TCAAAGAAAGGAGGAGAACGGTTAAGTATTTTAACCAAGAGCCTTTTGCTGAGGAGAACAAAAGACCAGCTGGACTCTACTGGCAGACCT
TTGGTGATACTGCCCCAGCGTAAATTTCAGTTGCACCATTTAAAGCTTTCTGAAGATGAAGAGACTGTTTACAATGTGTTTTTTGCAAGA
TCAAGGTCAGCTCTGCAATCCTATCTAAAAAGACATGAAAGTAGAGGCAACCAATCTGGAAGAAGCCCTAATAATCCATTCAGTAGAGTG
GCACTGGAGTTTGGGTCTGAGGAGCCTAGACACTCGGAGGCAGCAGACTCACCGAGATCCAGCACCGTCCACATACTGTCCCAGTTGCTG
AGACTCCGCCAGTGTTGCTGTCATCTTTCTTTACTGAAGTCGGCCCTGGATCCAATGGAACTGAAGGGTGAAGGTCTTGTCCTTTCCCTG
GAAGAACAGCTCAGTGCTTTGACCTTGTCAGAACTCCGTGACTCAGAGCCATCTTCCACTGTTTCCCTTAACGGCACCTTCTTCAAGATG
GAGCTTTTTGAAGGCATGCGAGAGAGCACCAAGATTTCATCTCTGTTGGCAGAATTGGAGGCAATTCAAAGAAATTCAGCATCCCAAAAG
AGTGTCATTGTCTCTCAGTGGACCAACATGCTGAAAGTTGTAGCATTGCACCTGAAGAAGCATGGACTGACTTATGCCACCATCGATGGC
TCTGTCAATCCCAAGCAGAGAATGGACTTGGTAGAGGCATTTAACCACTCCAGAGGCCCTCAGGTAATGCTAATCTCTCTCTTGGCCGGA
GGTGTTGGTCTAAACCTGACTGGAGGAAATCACCTCTTTCTTTTGGACATGCACTGGAATCCATCACTTGAAGATCAAGCTTGTGACCGA
ATTTACCGAGTAGGGCAGCAGAAAGATGTTGTCATACACAGATTTGTTTGTGAGGGAACAGTAGAAGAAAAGATCTTACAGCTCCAAGAA
AAAAAGAAAGATTTGGCCAAACAAGTTCTATCAGGGTCTGGAGAATCTGTCACCAAGCTCACCTTGGCTGACCTCAGAGTCCTTTTTGGC
ATCTAACCTCCTGTGGATAAGGGCTCAGAATAGCACCATTGCTGGTTTGTATTAGGATCTGGGAATAACAACCTAACCATGAGCCTTGAA
CTCTGTTCTTTGCATTTCAATTTCACCGTCAAGCCTTTCACCTTCCTCAAAATGAGGCATAATCTTATCCCCAGAATTGAGGAGGGGTTG
TGTTAACCAATTAGTTAACCAATTATGTTAATAATTTATTTAATGAGTGGTATGGAAACCAATTGATTTTTTTAGATAAAAGAATATGTT
TTAGAGTTGGATGATTTTGGAAAACAACTCTGGCAGAATTGTATATAAGCTTCAGTAAAGTTCAAAAAGCGGGCCAGGTGTGGTGGCTCA
TGCCTGTAATCCCGACACTTTGGGAGGCCAAGGCAGGAGGATGGCTTGAAGCCAGTAGTTCAAGACCAGCCTGGGCAACATAGTAAGACC
CCATCTCTATGAAGAATAAAAAAATGAGCTAGGCGTGGTAGTGCACACCTGTAGTCCTAGCTACTTGGGAGGCTGAGGCAGGAGGATCCC
TTGAGTCCAGGAGGTTGAGGCTGCAGTGAGCTGTGATTGTGCCACTGTTTTCCAGCCTGGGCAATACAGTGAGACCCTGTCTCAAAAAAA
GGAAAAAAAAGCTCAAAAAGTTCTGTGTTGCCTTTCTCTTCTTAGCTGATGATGGGAGAACCAGTTACTACCTTCTCTAACACAGGCTCC
ATCCTATCTCTTCATCTCTTCTTGCCAGTGATGTTGCACCTGTAACCATCTTTTTATGGGTGGAGCAGAGAGTCAATCCCTGCAGCCACC
CTGCAGCCAGCCATCTCTGCAGTTCTCTCAGTGCAGGCAGTTCTTCCTCTCAGGCTGAAGATCAAGGAGATGCTTTGTACATGAACAGAT
GCTGAGTATCTGTTATCATTGTATTGTTTAGTGTCAGTGTATCATTTAGTATTTGTATCACTGTACCATTTAGTGTTGTATATCACTCAG
TCATTTAATATTGGTTATCACCATACAGTTTAATATTTGTATCATTTGGTTCATTGTATCGTTTAGTATTTCTATTATAACATTTCTATT
TGTAGTATTTGTATAATATTTGTGTCATTTTTAATAGTATTTGTATTTTTACAAATTTGCAGTATTTGTAGCATTTAGTATCATTGTTTC
ATTTAGTATTTGGTACAATCTAATAAATACTAATCCAGTCCAATACTAATCCAATCCAATACTAATAATACTATTGGTACAATCCAATAC
TAATAATACTATTGGTACAATCCAATACTAATAATACTAACAGTAGTATTGATACAATCTAATAAATAATGTGTTTGACAGTGTAGCAGA
AATAATGCTATGTGTTCACCAAACCCACTTCCTTTTCCTCCCGGGCACCCAGAGAGACTGTATTTCCCAGTTTTTGCTGCAGTTTGACGG
GGTCCATATCAATGGACTGTGGAGAGAAGCGATTGATGTAAGTCACTTCTAGGTGGCCCTCTACCACTTTCCAAAAGATCATTCATGCTG
TTTCTTCCCTCCTCAGCCTATGGGATGCAAAGGAACTGATGGAAGATTACAAGGCCCTAGGGAAGGTGAAGCCACTAGCTCAGCAGTTCT
TAGCCTAGTTTTTGGCCATCAGCCCTTCTATTAGACTAGTGAAGCCTCAGTCCCAGGATGGCTCCCCATGTACACTTCCCTCCTCGCCCC
AGCTCACCTACACTGGACTATGACATGATCAAGGAATCTTTTTTTTTAAGCTACTGAGATTTCTGTGTTGTTTACATAGCAGTTTGTACC
CTAAACAAACACTTGAGATTTTATACTTCAGGAAACTATTCAGATTTCCTTCTCATTAGCAATTGTTCCAAAAACACTTACTCTGCTAAT
TTCTGCTAGAAAGAATCACAGTTCTTCTAACACAGAAACATTTCTGTCCCTTGAGTTGGGAAACAAGACCCTATGTTAACCCAGTCAGAG
TGTGGACTGAGGCATTCGGAGCCTATTTAAGCAGAAGTTTTCTATAAGGACAAGATTTAAAGGCTTACAAAGGTAAAGACAATGGCCTGG
TGGGAAGAATTCTAGTCTAGAACGTTTGAGATTTGACTCTAGTTCTAGGTTCATCTTAGCTGGGTGTGTAACGTTGAAAAAATTGGCCGG
GTGCAGTGGCTCAGGCCTGTCATCCCAGCACTTTGGGAGGCCGAGGCAGACGGATCACGAGGTCAAGAGATCAAGACCATCTTGGCCAAC
ATGGTGAAACCCCGTCTCTACTAAAAATACAAAAATTAGCTGAGCGTGGTGGCGTGCGCCTGTAGTCCCAGCTACTGGGGAGGATAAGGC
AGGAGAATCGCTTGAACCTGGGAGGTGGAGGTTGCAGTGAGCTGAGATCGCGCCATTGCACTCCAGCCTGGTGACAGAGCGAGACTCCGT
CTCAAAAAAAAAAAAAAAAAAAAAGAGAGAGAAAAAAATCCTTACTTTCTCTACACTCTGATTTCCTCATTTGTAAGGTGGGCAGTTTTC
AGAACTTAGCAGCAATAAGGTTTCTGATAAAATCAAGAAGCAAAGGAAGTAACATTGCCTTTTTGAAGTTTTGCTATAAGATTGACATAC
CAAGGTAAAGATTGAGTCACCTGAGAAGCAGTGGCTCCCAGGCCAGCAAGAATGTACAAACCTGGCTCTGCCATTTGCTGATTGATATTA
GGCAAGTTGCAGATTCCTTGGACATCTCAATCCTTTCATCTGTAAAATGTGTGGATTAGCATGTATCTCATGCTCCACTGGGAATTTCAT
AGCAAATATATATACTACAACATGGTTGACCAGATAGATCAGTAATGTCAACTAGAAGGTATTAGATGAACATTGTCAGTCTCCAATCAA
GCATTGTTTAGGGGAGAGGAATTCTTTCAGGTTCAAGCATTCTGGCTTTTAGTTTGGAGAGGGATGCAGGGATTGTAACTTAAAATCTTC
AGATATTGAGGCCATTGACAAGTAATCTACTGTAAGGTAGATGCCTCCTGGTATTTTAAAACAGCTTTTCTAATTTCTCATGTTATTGTA
CATAAGCAAAGCAACCTAGTTATGTCTTGGGTAGGTGTTCTTATAGCCGTGAGATGCTACTGACTTGAGGTGGATGCAGAAAAAAATGGA
ACCACTGCCTTAATGGGATGGAATATACTAAACATGCATTCTTAAATCCTAGTGCTGGGATGGATTACATGAATTACATTGTGGAGCTGC
ATATGTGTCTCCCCTCTTCCCTCCCTGGGGGTTAGGCTGGGTTTGTTTGGTTTTTTTTGTTTTGTCCTCATGAGGCTTAGCATCTAAGGG
AGACAGGCATGAATTAACAGAAGTGGCATTCTGGTATCTGTCTCAGCCTCATATTCATTTTAGTGTAAATCAGTTTCGTCAAGTCTAGGT
ATGACAAGGTGGGTCTTTGCACCTTCTAGCGATGGGCAGCATCCCACAACACAGTGGTCTAATTGAGGTGCTGCACTATGAGTCCTGCCT
GTGTTAACCAGCCTTCCTTCATGTCACAATACTGCTGCTGGATTTGCTTTTTACATCTGCCTATTGCACCTGACTTGGGCATGGATGATA
TGAGGTAATAAATGCTTTGAAAACCATGAAGGGCCACACAAGTGCTAGTGTTATTGCTGTGGGACAAGGTCTGGGAATATGAGAACCAGC
AGCAGCATGGGTGCAGCTGAGAACCAGATGGTGAACATCTGTCTCCAAAGTGCAACATTCCTGAGCACCGGATTTATAAGGCATTTCTTA
CTCGACAGAATTGACTTCATGGAAGGTATGTAGTTTGACTTTGCCTTAGCCATGTTGATCAAATAGGAGTATTGTGCATGCCGCAGCTAG
ACAGAGTCCTGGGCCCTTTAAAAACCTTGTCAGTGACTCCCATTGCAGGCCCAGCGCAGTGGTTCACACCTGTAATCCCAGCATTTGGGA
GGCTGAGGCAGGCAGATCACTTGAGGCCAAGAGTTCGAGACCAGACTGGCCAACATGGCAAAACCTCCTCTCTACTAAAAATACAAAAGT
TAGCCAGGCGTGATGTTGGGTGCCTGTAATTGCAGCTACTCGGGAGGCTGAGGCAGGAGAATCACTTGAATCCAGGAGGCGGAGGTTACA
GTGAGCTGAGATCATACCACTGCACTCCAGCCTGGGCCACAGAGAAAGAACGGTGATTCTTTCTAGCAGAAATTAGCAGAGTAAGTGTTT
TTGGAACAATTGCTAATGAAAAGAAGGAAAAACAGAAAAAAAAAATTTTCTGTTTATGGGAGGTGACTTATTTCTCTATCAATCCTGTGA
GTGATTTAGCATGGCAATTCATGAACACTGAGTTGTTTCCTTGCTCTGATTGTCTGTTGCTCAATGAAATGGCTTTTAGCAGGGCTCAAA
GGTGAAGCCAGATTCTCCTGCACTAATAGGATAAGCATGGAGACACCAGTGTTCAGTGTGGCCTCTGGTTGTCTGAAATTTTGCTGTCAA
CTCTAATACCTTGAAAGAATTAGGTTTCCAAAGTGGGATATTGTGCTGCTGTTTGTGATATAGCATCTAGACTTAGGAAAGGGCAGGAAC
AATTTAAAAGCACATCTGTAGGCACAAAGAGAATTATAATAGAAATTCAGAATTCCTAGGCATATGACCTAGACTAAAATGTCTTCATAA
CTACAAATGAAATCAGGGTCATTTATAGTACAAACTACCACAGAAGTCAGTAGTTAGGGGATGGAGATAGATATGAAAAAAAAAAAAAGC
AAACCCAGCCTAACTCCCAGGGAGGGAAGAGGGGCGACAGATATGCAGCTACACAATGTTTTTACTATCTTGAGTTCTTTTTACCCAGAT
TCCATAGCTAAATCCAGATGTATTAATAGGTAGAGACTACTTCAGAAAGGATGAGACTATTTTCTTGCTTAATTATCCACACAGTAATTC
AGAAATGTATATTGAACACTTTTTATATGCCAGGCACTGCTGGGCACTGGAAATATAAAAGTAAGCAAAAATGAAAAACTATCCTGTCCT
CCTGAGGCTTAGCATCTAAGGGAGACAGGCATTAGTCAACCCCGTGTGGCTGTGAATCAGCCATGATGCTGAGTGCTACAAGAGAGGACT
GTGCGGCTGGGAGGGCTTATAACAGGATTTGACCTAGTTAGGGAAGATCTGAGGAAGTGATGAAAGAATGGAAATCAATATGTAAGAGCT
CACAAGTCAGAGTGAGATGTTTCTTCCTATACTGCCTGCTTCTAATGAGCATCCACTTCATTGAACCACCTCTTCATTGAGCCAAACCTA
CCATACAGGGATACATTCTCTGGAGGAAAGTTGAGCAACTATTGCATTTGGGACATTAGAGTATGGGTGGGCTGACAGGTATGTGTATGT
TTATTATCCAAGACAGCCAAGGTGTTTATCCTGTTACAACATCCCAGAGGACAGAGGCTCTTATTTGTGACTCTTTTTTCTTACCTGTAA
CACCAGAGGCATAACGTACATCATAATGCTGCATCTTGTTGACGCTTCAATGCTCACAATTCAAAGGTGATTTCTGAAGCACTTTGTTAC
ACTGGGGACAGCTCCTAAATCCTCCCACTCTTTTTTTGCCTCACCTTGGAGTCTTGGGCTCTGTTGATCACTGACTCTGCCAGGTCTTTC
AGCAGGCAAGACAGCTCAGTTAAATTGAGTTTGGACTCCACTGTAGTGCATGCATGAGACAGCACCCCCAATCCCCAACACCCACACACA
AACTTTAAATATTTGTAACAGAATTGTTACCATTAATATTGCTTAAAGGCTAACACATTAGCCAGAACCTAGATGTCTTCTGGAAATTTT

>In-frame_ENST00000356554_ENST00000369466_TCGA-BH-A18Q-01A_MAN1A2_chr1_117984947_+_TTF2_chr1_117616283_length(amino acids)=1406AA_start in transcript=735_stop in transcript=4955
MTTPALLPLSGRRIPPLNLGPPSFPHHRATLRLSEKFILLLILSAFITLCFGAFFFLPDSSKHKRFDLGLEDVLIPHVDAGKGAKNPGVF
LIHGPDEHRHREEEERLRNKIRADHEKALEEAKEKLRKSREEIRAEIQTEKNKVVQEMKIKENKPLPPVPIPNLVGIRGGDPEDNDIREK
REKIKEMMKHAWDNYRTYGWGHNELRPIARKGHSPNIFGSSQMGATIVDALDTLYIMGLHDEFLDGQRWIEDNLDFSVNSEVSVFEVNIR
FIGGLLAAYYLSGEEIFKIKAVQLAEKLLPAFNTPTGIPWAMVNLKRLFFRCIRSKAEGKRWCGSIPWQDPDSKEHSVSNKSQHASETFH
HSSNWLRNPFKVLDKNQEPALWKQLIKGEGEEKKADKKQREKGDQLFDQKKEQKPEMMEKDLSSGLVPKKKQSVVQEKKQEEGAEIQCEA
ETGGTHKRDFSEIKSQQCQGNELTRPSASSQEKSSGKSQDVQRESEPLREKVTQLLPQNVHSHNSISKPQKGGPLNKEYTNWEAKETKAK
DGPSIQATQKSLPQGHFQERPETHSVPAPGGPAAQAAPAAPGLSLGEGREAATSSDDEEEDDVVFVSSKPGSPLLFDSTLDLETKENLQF
PDRSVQRKVSPASGVSKKVEPSDPVARRVYLTTQLKQKKSTLASVNIQALPDKGQKLIKQIQELEEVLSGLTLSPEQGTNEKSNSQVPQQ
SHFTKTTTGPPHLVPPQPLPRRGTQPVGSLELKSACQVTAGGSSQCYRGHTNQDHVHAVWKITSEAIGQLHRSLESCPGETVVAEDPAGL
KVPLLLHQKQALAWLLWRESQKPQGGILADDMGLGKTLTMIALILTQKNQEKKEEKEKSTALTWLSKDDSCDFTSHGTLIICPASLIHHW
KNEVEKRVNSNKLRVYLYHGPNRDSRARVLSTYDIVITTYSLVAKEIPTNKQEAEIPGANLNVEGTSTPLLRIAWARIILDEAHNVKNPR
VQTSIAVCKLQACARWAVTGTPIQNNLLDMYSLLKFLRCSPFDEFNLWRSQVDNGSKKGGERLSILTKSLLLRRTKDQLDSTGRPLVILP
QRKFQLHHLKLSEDEETVYNVFFARSRSALQSYLKRHESRGNQSGRSPNNPFSRVALEFGSEEPRHSEAADSPRSSTVHILSQLLRLRQC
CCHLSLLKSALDPMELKGEGLVLSLEEQLSALTLSELRDSEPSSTVSLNGTFFKMELFEGMRESTKISSLLAELEAIQRNSASQKSVIVS
QWTNMLKVVALHLKKHGLTYATIDGSVNPKQRMDLVEAFNHSRGPQVMLISLLAGGVGLNLTGGNHLFLLDMHWNPSLEDQACDRIYRVG

--------------------------------------------------------------
>In-frame_ENST00000356554_ENST00000369466_TCGA-B6-A0I1-01A_MAN1A2_chr1_117963271_+_TTF2_chr1_117639973_length(transcript)=7822nt_BP=1590nt
AGACCCGTGCGGTAGCAACAGCGGCGGCGGCCGCGGCGGCTGGCCGGACTCAGGTGTTTCGGACGCTATTGCCCTTCGCGCCAGCCGTCG
AGTGGGCAGCAGCGGGACTCAGCCGGGCGCCAGGTTCCTGCCAGGCAGCGCCGGGAAGCGCGGGCGGCCGAGAACTCCTTCCTGCTACTT
CGCCCAGCGCCGCTGCTTCGGCTTCCCAGCGAAGTGGGAGACCTTCCTCCCTGTTTGCAGACGTCCGTGGGAGACCCTTATTTTTTCCAC
CGCTAAGGTTAAGAGATTCTGGAATAGAAGCGTCGAAGGAGATCAAGTGAACCTTCTACAACTCCTCGGATGTCGCCAGTCTCCCTTTCG
GGGCGGAAGACTACGTTTGAGCATCTCACTGAGGTGCAGGAATGGAAGAACCCACCTTGCAGCTTTTCTGCAGTGTGGCTTGCCTGATCT
ACCCCTAGGAATGAAGAGGAGGCTTGTAATAATCCGATGAAGTACAGATGTTGAAGAGGATATCGCAGGACCTAAACTTGTGATCGTTTG
GGGGAGGTCACACACGTTTCTGAGTGGGAATGGATGGGCGTGAATGACGTGCCCTCTTAAAAAGCACAACAGTCCTTTAAGAGGAGCAAA
ATTGAGTTTTCCCATTTTGGCCAAGATTTTGAAGACAGTTCAATGTATTCTACATTTGACATAAGATGAGAACTTTCTAAAGTATTCTCT
CCAAGAGCGTAAACGATGACTACCCCAGCCCTGCTGCCCCTCTCTGGACGTAGGATACCACCTCTGAACCTGGGGCCGCCTTCCTTCCCA
CATCACAGGGCTACCTTGAGACTTTCTGAGAAGTTTATTCTTCTCCTTATTCTTAGTGCCTTCATCACTCTGTGTTTTGGGGCATTCTTT
TTCCTTCCAGACTCTTCAAAACACAAACGCTTTGATTTGGGTTTAGAAGATGTGTTAATTCCACATGTAGATGCCGGTAAAGGGGCTAAA
AACCCCGGAGTCTTCCTGATCCATGGACCCGATGAACATAGACACAGGGAAGAGGAAGAACGTCTGAGAAATAAAATTCGAGCTGATCAT
GAGAAGGCCTTGGAAGAAGCAAAAGAAAAATTAAGAAAGTCAAGAGAGGAAATTCGAGCAGAAATTCAGACAGAGAAAAATAAGGTAGTC
CAAGAAATGAAGATAAAAGAGAACAAGCCACTGCCACCAGTCCCTATTCCCAACCTTGTAGGAATACGTGGTGGAGACCCAGAAGATAAT
GACATAAGAGAGAAAAGGGAAAAAATTAAAGAGATGATGAAACATGCTTGGGATAACTATAGGACATATGGGTGGGGACATAATGAACTC
AGACCTATTGCAAGGAAAGGACACTCCCCTAACATATTTGGAAGTTCACAAATGGGTGCTACCATAGTAGATGCTTTGGATACCCTTTAT
ATCATGGGACTTCATGATGAATTCCTAGATGGGCAAAGATGGATTGAAGACAACCTTGATTTCAGTGTGAATTCAGAGGTGTCTGTGTTT
GAAGTCAACATTCGATTTATTGGAGGCCTACTTGCAGCATATTACCTATCAGGAGAGGAGGTAATGCTAATCTCTCTCTTGGCCGGAGGT
GTTGGTCTAAACCTGACTGGAGGAAATCACCTCTTTCTTTTGGACATGCACTGGAATCCATCACTTGAAGATCAAGCTTGTGACCGAATT
TACCGAGTAGGGCAGCAGAAAGATGTTGTCATACACAGATTTGTTTGTGAGGGAACAGTAGAAGAAAAGATCTTACAGCTCCAAGAAAAA
AAGAAAGATTTGGCCAAACAAGTTCTATCAGGGTCTGGAGAATCTGTCACCAAGCTCACCTTGGCTGACCTCAGAGTCCTTTTTGGCATC
TAACCTCCTGTGGATAAGGGCTCAGAATAGCACCATTGCTGGTTTGTATTAGGATCTGGGAATAACAACCTAACCATGAGCCTTGAACTC
TGTTCTTTGCATTTCAATTTCACCGTCAAGCCTTTCACCTTCCTCAAAATGAGGCATAATCTTATCCCCAGAATTGAGGAGGGGTTGTGT
TAACCAATTAGTTAACCAATTATGTTAATAATTTATTTAATGAGTGGTATGGAAACCAATTGATTTTTTTAGATAAAAGAATATGTTTTA
GAGTTGGATGATTTTGGAAAACAACTCTGGCAGAATTGTATATAAGCTTCAGTAAAGTTCAAAAAGCGGGCCAGGTGTGGTGGCTCATGC
CTGTAATCCCGACACTTTGGGAGGCCAAGGCAGGAGGATGGCTTGAAGCCAGTAGTTCAAGACCAGCCTGGGCAACATAGTAAGACCCCA
TCTCTATGAAGAATAAAAAAATGAGCTAGGCGTGGTAGTGCACACCTGTAGTCCTAGCTACTTGGGAGGCTGAGGCAGGAGGATCCCTTG
AGTCCAGGAGGTTGAGGCTGCAGTGAGCTGTGATTGTGCCACTGTTTTCCAGCCTGGGCAATACAGTGAGACCCTGTCTCAAAAAAAGGA
AAAAAAAGCTCAAAAAGTTCTGTGTTGCCTTTCTCTTCTTAGCTGATGATGGGAGAACCAGTTACTACCTTCTCTAACACAGGCTCCATC
CTATCTCTTCATCTCTTCTTGCCAGTGATGTTGCACCTGTAACCATCTTTTTATGGGTGGAGCAGAGAGTCAATCCCTGCAGCCACCCTG
CAGCCAGCCATCTCTGCAGTTCTCTCAGTGCAGGCAGTTCTTCCTCTCAGGCTGAAGATCAAGGAGATGCTTTGTACATGAACAGATGCT
GAGTATCTGTTATCATTGTATTGTTTAGTGTCAGTGTATCATTTAGTATTTGTATCACTGTACCATTTAGTGTTGTATATCACTCAGTCA
TTTAATATTGGTTATCACCATACAGTTTAATATTTGTATCATTTGGTTCATTGTATCGTTTAGTATTTCTATTATAACATTTCTATTTGT
AGTATTTGTATAATATTTGTGTCATTTTTAATAGTATTTGTATTTTTACAAATTTGCAGTATTTGTAGCATTTAGTATCATTGTTTCATT
TAGTATTTGGTACAATCTAATAAATACTAATCCAGTCCAATACTAATCCAATCCAATACTAATAATACTATTGGTACAATCCAATACTAA
TAATACTATTGGTACAATCCAATACTAATAATACTAACAGTAGTATTGATACAATCTAATAAATAATGTGTTTGACAGTGTAGCAGAAAT
AATGCTATGTGTTCACCAAACCCACTTCCTTTTCCTCCCGGGCACCCAGAGAGACTGTATTTCCCAGTTTTTGCTGCAGTTTGACGGGGT
CCATATCAATGGACTGTGGAGAGAAGCGATTGATGTAAGTCACTTCTAGGTGGCCCTCTACCACTTTCCAAAAGATCATTCATGCTGTTT
CTTCCCTCCTCAGCCTATGGGATGCAAAGGAACTGATGGAAGATTACAAGGCCCTAGGGAAGGTGAAGCCACTAGCTCAGCAGTTCTTAG
CCTAGTTTTTGGCCATCAGCCCTTCTATTAGACTAGTGAAGCCTCAGTCCCAGGATGGCTCCCCATGTACACTTCCCTCCTCGCCCCAGC
TCACCTACACTGGACTATGACATGATCAAGGAATCTTTTTTTTTAAGCTACTGAGATTTCTGTGTTGTTTACATAGCAGTTTGTACCCTA
AACAAACACTTGAGATTTTATACTTCAGGAAACTATTCAGATTTCCTTCTCATTAGCAATTGTTCCAAAAACACTTACTCTGCTAATTTC
TGCTAGAAAGAATCACAGTTCTTCTAACACAGAAACATTTCTGTCCCTTGAGTTGGGAAACAAGACCCTATGTTAACCCAGTCAGAGTGT
GGACTGAGGCATTCGGAGCCTATTTAAGCAGAAGTTTTCTATAAGGACAAGATTTAAAGGCTTACAAAGGTAAAGACAATGGCCTGGTGG
GAAGAATTCTAGTCTAGAACGTTTGAGATTTGACTCTAGTTCTAGGTTCATCTTAGCTGGGTGTGTAACGTTGAAAAAATTGGCCGGGTG
CAGTGGCTCAGGCCTGTCATCCCAGCACTTTGGGAGGCCGAGGCAGACGGATCACGAGGTCAAGAGATCAAGACCATCTTGGCCAACATG
GTGAAACCCCGTCTCTACTAAAAATACAAAAATTAGCTGAGCGTGGTGGCGTGCGCCTGTAGTCCCAGCTACTGGGGAGGATAAGGCAGG
AGAATCGCTTGAACCTGGGAGGTGGAGGTTGCAGTGAGCTGAGATCGCGCCATTGCACTCCAGCCTGGTGACAGAGCGAGACTCCGTCTC
AAAAAAAAAAAAAAAAAAAAAGAGAGAGAAAAAAATCCTTACTTTCTCTACACTCTGATTTCCTCATTTGTAAGGTGGGCAGTTTTCAGA
ACTTAGCAGCAATAAGGTTTCTGATAAAATCAAGAAGCAAAGGAAGTAACATTGCCTTTTTGAAGTTTTGCTATAAGATTGACATACCAA
GGTAAAGATTGAGTCACCTGAGAAGCAGTGGCTCCCAGGCCAGCAAGAATGTACAAACCTGGCTCTGCCATTTGCTGATTGATATTAGGC
AAGTTGCAGATTCCTTGGACATCTCAATCCTTTCATCTGTAAAATGTGTGGATTAGCATGTATCTCATGCTCCACTGGGAATTTCATAGC
AAATATATATACTACAACATGGTTGACCAGATAGATCAGTAATGTCAACTAGAAGGTATTAGATGAACATTGTCAGTCTCCAATCAAGCA
TTGTTTAGGGGAGAGGAATTCTTTCAGGTTCAAGCATTCTGGCTTTTAGTTTGGAGAGGGATGCAGGGATTGTAACTTAAAATCTTCAGA
TATTGAGGCCATTGACAAGTAATCTACTGTAAGGTAGATGCCTCCTGGTATTTTAAAACAGCTTTTCTAATTTCTCATGTTATTGTACAT
AAGCAAAGCAACCTAGTTATGTCTTGGGTAGGTGTTCTTATAGCCGTGAGATGCTACTGACTTGAGGTGGATGCAGAAAAAAATGGAACC
ACTGCCTTAATGGGATGGAATATACTAAACATGCATTCTTAAATCCTAGTGCTGGGATGGATTACATGAATTACATTGTGGAGCTGCATA
TGTGTCTCCCCTCTTCCCTCCCTGGGGGTTAGGCTGGGTTTGTTTGGTTTTTTTTGTTTTGTCCTCATGAGGCTTAGCATCTAAGGGAGA
CAGGCATGAATTAACAGAAGTGGCATTCTGGTATCTGTCTCAGCCTCATATTCATTTTAGTGTAAATCAGTTTCGTCAAGTCTAGGTATG
ACAAGGTGGGTCTTTGCACCTTCTAGCGATGGGCAGCATCCCACAACACAGTGGTCTAATTGAGGTGCTGCACTATGAGTCCTGCCTGTG
TTAACCAGCCTTCCTTCATGTCACAATACTGCTGCTGGATTTGCTTTTTACATCTGCCTATTGCACCTGACTTGGGCATGGATGATATGA
GGTAATAAATGCTTTGAAAACCATGAAGGGCCACACAAGTGCTAGTGTTATTGCTGTGGGACAAGGTCTGGGAATATGAGAACCAGCAGC
AGCATGGGTGCAGCTGAGAACCAGATGGTGAACATCTGTCTCCAAAGTGCAACATTCCTGAGCACCGGATTTATAAGGCATTTCTTACTC
GACAGAATTGACTTCATGGAAGGTATGTAGTTTGACTTTGCCTTAGCCATGTTGATCAAATAGGAGTATTGTGCATGCCGCAGCTAGACA
GAGTCCTGGGCCCTTTAAAAACCTTGTCAGTGACTCCCATTGCAGGCCCAGCGCAGTGGTTCACACCTGTAATCCCAGCATTTGGGAGGC
TGAGGCAGGCAGATCACTTGAGGCCAAGAGTTCGAGACCAGACTGGCCAACATGGCAAAACCTCCTCTCTACTAAAAATACAAAAGTTAG
CCAGGCGTGATGTTGGGTGCCTGTAATTGCAGCTACTCGGGAGGCTGAGGCAGGAGAATCACTTGAATCCAGGAGGCGGAGGTTACAGTG
AGCTGAGATCATACCACTGCACTCCAGCCTGGGCCACAGAGAAAGAACGGTGATTCTTTCTAGCAGAAATTAGCAGAGTAAGTGTTTTTG
GAACAATTGCTAATGAAAAGAAGGAAAAACAGAAAAAAAAAATTTTCTGTTTATGGGAGGTGACTTATTTCTCTATCAATCCTGTGAGTG
ATTTAGCATGGCAATTCATGAACACTGAGTTGTTTCCTTGCTCTGATTGTCTGTTGCTCAATGAAATGGCTTTTAGCAGGGCTCAAAGGT
GAAGCCAGATTCTCCTGCACTAATAGGATAAGCATGGAGACACCAGTGTTCAGTGTGGCCTCTGGTTGTCTGAAATTTTGCTGTCAACTC
TAATACCTTGAAAGAATTAGGTTTCCAAAGTGGGATATTGTGCTGCTGTTTGTGATATAGCATCTAGACTTAGGAAAGGGCAGGAACAAT
TTAAAAGCACATCTGTAGGCACAAAGAGAATTATAATAGAAATTCAGAATTCCTAGGCATATGACCTAGACTAAAATGTCTTCATAACTA
CAAATGAAATCAGGGTCATTTATAGTACAAACTACCACAGAAGTCAGTAGTTAGGGGATGGAGATAGATATGAAAAAAAAAAAAAGCAAA
CCCAGCCTAACTCCCAGGGAGGGAAGAGGGGCGACAGATATGCAGCTACACAATGTTTTTACTATCTTGAGTTCTTTTTACCCAGATTCC
ATAGCTAAATCCAGATGTATTAATAGGTAGAGACTACTTCAGAAAGGATGAGACTATTTTCTTGCTTAATTATCCACACAGTAATTCAGA
AATGTATATTGAACACTTTTTATATGCCAGGCACTGCTGGGCACTGGAAATATAAAAGTAAGCAAAAATGAAAAACTATCCTGTCCTCCT
GAGGCTTAGCATCTAAGGGAGACAGGCATTAGTCAACCCCGTGTGGCTGTGAATCAGCCATGATGCTGAGTGCTACAAGAGAGGACTGTG
CGGCTGGGAGGGCTTATAACAGGATTTGACCTAGTTAGGGAAGATCTGAGGAAGTGATGAAAGAATGGAAATCAATATGTAAGAGCTCAC
AAGTCAGAGTGAGATGTTTCTTCCTATACTGCCTGCTTCTAATGAGCATCCACTTCATTGAACCACCTCTTCATTGAGCCAAACCTACCA
TACAGGGATACATTCTCTGGAGGAAAGTTGAGCAACTATTGCATTTGGGACATTAGAGTATGGGTGGGCTGACAGGTATGTGTATGTTTA
TTATCCAAGACAGCCAAGGTGTTTATCCTGTTACAACATCCCAGAGGACAGAGGCTCTTATTTGTGACTCTTTTTTCTTACCTGTAACAC
CAGAGGCATAACGTACATCATAATGCTGCATCTTGTTGACGCTTCAATGCTCACAATTCAAAGGTGATTTCTGAAGCACTTTGTTACACT
GGGGACAGCTCCTAAATCCTCCCACTCTTTTTTTGCCTCACCTTGGAGTCTTGGGCTCTGTTGATCACTGACTCTGCCAGGTCTTTCAGC
AGGCAAGACAGCTCAGTTAAATTGAGTTTGGACTCCACTGTAGTGCATGCATGAGACAGCACCCCCAATCCCCAACACCCACACACAAAC
TTTAAATATTTGTAACAGAATTGTTACCATTAATATTGCTTAAAGGCTAACACATTAGCCAGAACCTAGATGTCTTCTGGAAATTTTTTA

>In-frame_ENST00000356554_ENST00000369466_TCGA-B6-A0I1-01A_MAN1A2_chr1_117963271_+_TTF2_chr1_117639973_length(amino acids)=385AA_start in transcript=735_stop in transcript=1892
MTTPALLPLSGRRIPPLNLGPPSFPHHRATLRLSEKFILLLILSAFITLCFGAFFFLPDSSKHKRFDLGLEDVLIPHVDAGKGAKNPGVF
LIHGPDEHRHREEEERLRNKIRADHEKALEEAKEKLRKSREEIRAEIQTEKNKVVQEMKIKENKPLPPVPIPNLVGIRGGDPEDNDIREK
REKIKEMMKHAWDNYRTYGWGHNELRPIARKGHSPNIFGSSQMGATIVDALDTLYIMGLHDEFLDGQRWIEDNLDFSVNSEVSVFEVNIR
FIGGLLAAYYLSGEEVMLISLLAGGVGLNLTGGNHLFLLDMHWNPSLEDQACDRIYRVGQQKDVVIHRFVCEGTVEEKILQLQEKKKDLA

--------------------------------------------------------------
>In-frame_ENST00000356554_ENST00000369466_TCGA-13-0760-01A_MAN1A2_chr1_117963271_+_TTF2_chr1_117622190_length(transcript)=9307nt_BP=1590nt
AGACCCGTGCGGTAGCAACAGCGGCGGCGGCCGCGGCGGCTGGCCGGACTCAGGTGTTTCGGACGCTATTGCCCTTCGCGCCAGCCGTCG
AGTGGGCAGCAGCGGGACTCAGCCGGGCGCCAGGTTCCTGCCAGGCAGCGCCGGGAAGCGCGGGCGGCCGAGAACTCCTTCCTGCTACTT
CGCCCAGCGCCGCTGCTTCGGCTTCCCAGCGAAGTGGGAGACCTTCCTCCCTGTTTGCAGACGTCCGTGGGAGACCCTTATTTTTTCCAC
CGCTAAGGTTAAGAGATTCTGGAATAGAAGCGTCGAAGGAGATCAAGTGAACCTTCTACAACTCCTCGGATGTCGCCAGTCTCCCTTTCG
GGGCGGAAGACTACGTTTGAGCATCTCACTGAGGTGCAGGAATGGAAGAACCCACCTTGCAGCTTTTCTGCAGTGTGGCTTGCCTGATCT
ACCCCTAGGAATGAAGAGGAGGCTTGTAATAATCCGATGAAGTACAGATGTTGAAGAGGATATCGCAGGACCTAAACTTGTGATCGTTTG
GGGGAGGTCACACACGTTTCTGAGTGGGAATGGATGGGCGTGAATGACGTGCCCTCTTAAAAAGCACAACAGTCCTTTAAGAGGAGCAAA
ATTGAGTTTTCCCATTTTGGCCAAGATTTTGAAGACAGTTCAATGTATTCTACATTTGACATAAGATGAGAACTTTCTAAAGTATTCTCT
CCAAGAGCGTAAACGATGACTACCCCAGCCCTGCTGCCCCTCTCTGGACGTAGGATACCACCTCTGAACCTGGGGCCGCCTTCCTTCCCA
CATCACAGGGCTACCTTGAGACTTTCTGAGAAGTTTATTCTTCTCCTTATTCTTAGTGCCTTCATCACTCTGTGTTTTGGGGCATTCTTT
TTCCTTCCAGACTCTTCAAAACACAAACGCTTTGATTTGGGTTTAGAAGATGTGTTAATTCCACATGTAGATGCCGGTAAAGGGGCTAAA
AACCCCGGAGTCTTCCTGATCCATGGACCCGATGAACATAGACACAGGGAAGAGGAAGAACGTCTGAGAAATAAAATTCGAGCTGATCAT
GAGAAGGCCTTGGAAGAAGCAAAAGAAAAATTAAGAAAGTCAAGAGAGGAAATTCGAGCAGAAATTCAGACAGAGAAAAATAAGGTAGTC
CAAGAAATGAAGATAAAAGAGAACAAGCCACTGCCACCAGTCCCTATTCCCAACCTTGTAGGAATACGTGGTGGAGACCCAGAAGATAAT
GACATAAGAGAGAAAAGGGAAAAAATTAAAGAGATGATGAAACATGCTTGGGATAACTATAGGACATATGGGTGGGGACATAATGAACTC
AGACCTATTGCAAGGAAAGGACACTCCCCTAACATATTTGGAAGTTCACAAATGGGTGCTACCATAGTAGATGCTTTGGATACCCTTTAT
ATCATGGGACTTCATGATGAATTCCTAGATGGGCAAAGATGGATTGAAGACAACCTTGATTTCAGTGTGAATTCAGAGGTGTCTGTGTTT
GAAGTCAACATTCGATTTATTGGAGGCCTACTTGCAGCATATTACCTATCAGGAGAGGAGGTCCCTTTGCTACTACACCAGAAGCAGGCA
TTGGCTTGGTTACTATGGCGAGAAAGTCAGAAGCCACAAGGAGGAATTCTGGCAGATGATATGGGCTTAGGAAAAACCCTGACAATGATT
GCGCTCATCCTGACCCAGAAGAATCAAGAGAAAAAGGAAGAAAAGGAGAAAAGCACAGCTTTGACGTGGCTCTCCAAAGATGACTCTTGT
GACTTTACTTCCCATGGAACACTAATCATCTGTCCTGCCTCCCTGATCCATCATTGGAAAAATGAGGTGGAGAAACGGGTGAACAGCAAC
AAACTAAGAGTCTATCTCTACCATGGGCCAAACCGGGATTCACGTGCCAGAGTCCTCTCTACATATGACATCGTGATCACTACCTATAGC
CTCGTGGCCAAGGAGATTCCCACAAACAAGCAAGAGGCAGAGATCCCAGGTGCAAACCTCAATGTGGAGGGCACCTCAACACCTTTGCTT
CGAATAGCCTGGGCTCGAATCATATTGGATGAAGCTCACAATGTTAAGAATCCCCGAGTGCAGACTTCCATAGCTGTGTGTAAGCTACAA
GCCTGTGCCCGTTGGGCTGTCACTGGAACCCCCATTCAAAACAACTTATTGGATATGTATTCGCTGCTGAAGTTTCTCCGTTGCTCTCCA
TTTGATGAGTTCAATCTGTGGAGGAGTCAGGTTGACAATGGCTCAAAGAAAGGAGGAGAACGGTTAAGTATTTTAACCAAGAGCCTTTTG
CTGAGGAGAACAAAAGACCAGCTGGACTCTACTGGCAGACCTTTGGTGATACTGCCCCAGCGTAAATTTCAGTTGCACCATTTAAAGCTT
TCTGAAGATGAAGAGACTGTTTACAATGTGTTTTTTGCAAGATCAAGGTCAGCTCTGCAATCCTATCTAAAAAGACATGAAAGTAGAGGC
AACCAATCTGGAAGAAGCCCTAATAATCCATTCAGTAGAGTGGCACTGGAGTTTGGGTCTGAGGAGCCTAGACACTCGGAGGCAGCAGAC
TCACCGAGATCCAGCACCGTCCACATACTGTCCCAGTTGCTGAGACTCCGCCAGTGTTGCTGTCATCTTTCTTTACTGAAGTCGGCCCTG
GATCCAATGGAACTGAAGGGTGAAGGTCTTGTCCTTTCCCTGGAAGAACAGCTCAGTGCTTTGACCTTGTCAGAACTCCGTGACTCAGAG
CCATCTTCCACTGTTTCCCTTAACGGCACCTTCTTCAAGATGGAGCTTTTTGAAGGCATGCGAGAGAGCACCAAGATTTCATCTCTGTTG
GCAGAATTGGAGGCAATTCAAAGAAATTCAGCATCCCAAAAGAGTGTCATTGTCTCTCAGTGGACCAACATGCTGAAAGTTGTAGCATTG
CACCTGAAGAAGCATGGACTGACTTATGCCACCATCGATGGCTCTGTCAATCCCAAGCAGAGAATGGACTTGGTAGAGGCATTTAACCAC
TCCAGAGGCCCTCAGGTAATGCTAATCTCTCTCTTGGCCGGAGGTGTTGGTCTAAACCTGACTGGAGGAAATCACCTCTTTCTTTTGGAC
ATGCACTGGAATCCATCACTTGAAGATCAAGCTTGTGACCGAATTTACCGAGTAGGGCAGCAGAAAGATGTTGTCATACACAGATTTGTT
TGTGAGGGAACAGTAGAAGAAAAGATCTTACAGCTCCAAGAAAAAAAGAAAGATTTGGCCAAACAAGTTCTATCAGGGTCTGGAGAATCT
GTCACCAAGCTCACCTTGGCTGACCTCAGAGTCCTTTTTGGCATCTAACCTCCTGTGGATAAGGGCTCAGAATAGCACCATTGCTGGTTT
GTATTAGGATCTGGGAATAACAACCTAACCATGAGCCTTGAACTCTGTTCTTTGCATTTCAATTTCACCGTCAAGCCTTTCACCTTCCTC
AAAATGAGGCATAATCTTATCCCCAGAATTGAGGAGGGGTTGTGTTAACCAATTAGTTAACCAATTATGTTAATAATTTATTTAATGAGT
GGTATGGAAACCAATTGATTTTTTTAGATAAAAGAATATGTTTTAGAGTTGGATGATTTTGGAAAACAACTCTGGCAGAATTGTATATAA
GCTTCAGTAAAGTTCAAAAAGCGGGCCAGGTGTGGTGGCTCATGCCTGTAATCCCGACACTTTGGGAGGCCAAGGCAGGAGGATGGCTTG
AAGCCAGTAGTTCAAGACCAGCCTGGGCAACATAGTAAGACCCCATCTCTATGAAGAATAAAAAAATGAGCTAGGCGTGGTAGTGCACAC
CTGTAGTCCTAGCTACTTGGGAGGCTGAGGCAGGAGGATCCCTTGAGTCCAGGAGGTTGAGGCTGCAGTGAGCTGTGATTGTGCCACTGT
TTTCCAGCCTGGGCAATACAGTGAGACCCTGTCTCAAAAAAAGGAAAAAAAAGCTCAAAAAGTTCTGTGTTGCCTTTCTCTTCTTAGCTG
ATGATGGGAGAACCAGTTACTACCTTCTCTAACACAGGCTCCATCCTATCTCTTCATCTCTTCTTGCCAGTGATGTTGCACCTGTAACCA
TCTTTTTATGGGTGGAGCAGAGAGTCAATCCCTGCAGCCACCCTGCAGCCAGCCATCTCTGCAGTTCTCTCAGTGCAGGCAGTTCTTCCT
CTCAGGCTGAAGATCAAGGAGATGCTTTGTACATGAACAGATGCTGAGTATCTGTTATCATTGTATTGTTTAGTGTCAGTGTATCATTTA
GTATTTGTATCACTGTACCATTTAGTGTTGTATATCACTCAGTCATTTAATATTGGTTATCACCATACAGTTTAATATTTGTATCATTTG
GTTCATTGTATCGTTTAGTATTTCTATTATAACATTTCTATTTGTAGTATTTGTATAATATTTGTGTCATTTTTAATAGTATTTGTATTT
TTACAAATTTGCAGTATTTGTAGCATTTAGTATCATTGTTTCATTTAGTATTTGGTACAATCTAATAAATACTAATCCAGTCCAATACTA
ATCCAATCCAATACTAATAATACTATTGGTACAATCCAATACTAATAATACTATTGGTACAATCCAATACTAATAATACTAACAGTAGTA
TTGATACAATCTAATAAATAATGTGTTTGACAGTGTAGCAGAAATAATGCTATGTGTTCACCAAACCCACTTCCTTTTCCTCCCGGGCAC
CCAGAGAGACTGTATTTCCCAGTTTTTGCTGCAGTTTGACGGGGTCCATATCAATGGACTGTGGAGAGAAGCGATTGATGTAAGTCACTT
CTAGGTGGCCCTCTACCACTTTCCAAAAGATCATTCATGCTGTTTCTTCCCTCCTCAGCCTATGGGATGCAAAGGAACTGATGGAAGATT
ACAAGGCCCTAGGGAAGGTGAAGCCACTAGCTCAGCAGTTCTTAGCCTAGTTTTTGGCCATCAGCCCTTCTATTAGACTAGTGAAGCCTC
AGTCCCAGGATGGCTCCCCATGTACACTTCCCTCCTCGCCCCAGCTCACCTACACTGGACTATGACATGATCAAGGAATCTTTTTTTTTA
AGCTACTGAGATTTCTGTGTTGTTTACATAGCAGTTTGTACCCTAAACAAACACTTGAGATTTTATACTTCAGGAAACTATTCAGATTTC
CTTCTCATTAGCAATTGTTCCAAAAACACTTACTCTGCTAATTTCTGCTAGAAAGAATCACAGTTCTTCTAACACAGAAACATTTCTGTC
CCTTGAGTTGGGAAACAAGACCCTATGTTAACCCAGTCAGAGTGTGGACTGAGGCATTCGGAGCCTATTTAAGCAGAAGTTTTCTATAAG
GACAAGATTTAAAGGCTTACAAAGGTAAAGACAATGGCCTGGTGGGAAGAATTCTAGTCTAGAACGTTTGAGATTTGACTCTAGTTCTAG
GTTCATCTTAGCTGGGTGTGTAACGTTGAAAAAATTGGCCGGGTGCAGTGGCTCAGGCCTGTCATCCCAGCACTTTGGGAGGCCGAGGCA
GACGGATCACGAGGTCAAGAGATCAAGACCATCTTGGCCAACATGGTGAAACCCCGTCTCTACTAAAAATACAAAAATTAGCTGAGCGTG
GTGGCGTGCGCCTGTAGTCCCAGCTACTGGGGAGGATAAGGCAGGAGAATCGCTTGAACCTGGGAGGTGGAGGTTGCAGTGAGCTGAGAT
CGCGCCATTGCACTCCAGCCTGGTGACAGAGCGAGACTCCGTCTCAAAAAAAAAAAAAAAAAAAAAGAGAGAGAAAAAAATCCTTACTTT
CTCTACACTCTGATTTCCTCATTTGTAAGGTGGGCAGTTTTCAGAACTTAGCAGCAATAAGGTTTCTGATAAAATCAAGAAGCAAAGGAA
GTAACATTGCCTTTTTGAAGTTTTGCTATAAGATTGACATACCAAGGTAAAGATTGAGTCACCTGAGAAGCAGTGGCTCCCAGGCCAGCA
AGAATGTACAAACCTGGCTCTGCCATTTGCTGATTGATATTAGGCAAGTTGCAGATTCCTTGGACATCTCAATCCTTTCATCTGTAAAAT
GTGTGGATTAGCATGTATCTCATGCTCCACTGGGAATTTCATAGCAAATATATATACTACAACATGGTTGACCAGATAGATCAGTAATGT
CAACTAGAAGGTATTAGATGAACATTGTCAGTCTCCAATCAAGCATTGTTTAGGGGAGAGGAATTCTTTCAGGTTCAAGCATTCTGGCTT
TTAGTTTGGAGAGGGATGCAGGGATTGTAACTTAAAATCTTCAGATATTGAGGCCATTGACAAGTAATCTACTGTAAGGTAGATGCCTCC
TGGTATTTTAAAACAGCTTTTCTAATTTCTCATGTTATTGTACATAAGCAAAGCAACCTAGTTATGTCTTGGGTAGGTGTTCTTATAGCC
GTGAGATGCTACTGACTTGAGGTGGATGCAGAAAAAAATGGAACCACTGCCTTAATGGGATGGAATATACTAAACATGCATTCTTAAATC
CTAGTGCTGGGATGGATTACATGAATTACATTGTGGAGCTGCATATGTGTCTCCCCTCTTCCCTCCCTGGGGGTTAGGCTGGGTTTGTTT
GGTTTTTTTTGTTTTGTCCTCATGAGGCTTAGCATCTAAGGGAGACAGGCATGAATTAACAGAAGTGGCATTCTGGTATCTGTCTCAGCC
TCATATTCATTTTAGTGTAAATCAGTTTCGTCAAGTCTAGGTATGACAAGGTGGGTCTTTGCACCTTCTAGCGATGGGCAGCATCCCACA
ACACAGTGGTCTAATTGAGGTGCTGCACTATGAGTCCTGCCTGTGTTAACCAGCCTTCCTTCATGTCACAATACTGCTGCTGGATTTGCT
TTTTACATCTGCCTATTGCACCTGACTTGGGCATGGATGATATGAGGTAATAAATGCTTTGAAAACCATGAAGGGCCACACAAGTGCTAG
TGTTATTGCTGTGGGACAAGGTCTGGGAATATGAGAACCAGCAGCAGCATGGGTGCAGCTGAGAACCAGATGGTGAACATCTGTCTCCAA
AGTGCAACATTCCTGAGCACCGGATTTATAAGGCATTTCTTACTCGACAGAATTGACTTCATGGAAGGTATGTAGTTTGACTTTGCCTTA
GCCATGTTGATCAAATAGGAGTATTGTGCATGCCGCAGCTAGACAGAGTCCTGGGCCCTTTAAAAACCTTGTCAGTGACTCCCATTGCAG
GCCCAGCGCAGTGGTTCACACCTGTAATCCCAGCATTTGGGAGGCTGAGGCAGGCAGATCACTTGAGGCCAAGAGTTCGAGACCAGACTG
GCCAACATGGCAAAACCTCCTCTCTACTAAAAATACAAAAGTTAGCCAGGCGTGATGTTGGGTGCCTGTAATTGCAGCTACTCGGGAGGC
TGAGGCAGGAGAATCACTTGAATCCAGGAGGCGGAGGTTACAGTGAGCTGAGATCATACCACTGCACTCCAGCCTGGGCCACAGAGAAAG
AACGGTGATTCTTTCTAGCAGAAATTAGCAGAGTAAGTGTTTTTGGAACAATTGCTAATGAAAAGAAGGAAAAACAGAAAAAAAAAATTT
TCTGTTTATGGGAGGTGACTTATTTCTCTATCAATCCTGTGAGTGATTTAGCATGGCAATTCATGAACACTGAGTTGTTTCCTTGCTCTG
ATTGTCTGTTGCTCAATGAAATGGCTTTTAGCAGGGCTCAAAGGTGAAGCCAGATTCTCCTGCACTAATAGGATAAGCATGGAGACACCA
GTGTTCAGTGTGGCCTCTGGTTGTCTGAAATTTTGCTGTCAACTCTAATACCTTGAAAGAATTAGGTTTCCAAAGTGGGATATTGTGCTG
CTGTTTGTGATATAGCATCTAGACTTAGGAAAGGGCAGGAACAATTTAAAAGCACATCTGTAGGCACAAAGAGAATTATAATAGAAATTC
AGAATTCCTAGGCATATGACCTAGACTAAAATGTCTTCATAACTACAAATGAAATCAGGGTCATTTATAGTACAAACTACCACAGAAGTC
AGTAGTTAGGGGATGGAGATAGATATGAAAAAAAAAAAAAGCAAACCCAGCCTAACTCCCAGGGAGGGAAGAGGGGCGACAGATATGCAG
CTACACAATGTTTTTACTATCTTGAGTTCTTTTTACCCAGATTCCATAGCTAAATCCAGATGTATTAATAGGTAGAGACTACTTCAGAAA
GGATGAGACTATTTTCTTGCTTAATTATCCACACAGTAATTCAGAAATGTATATTGAACACTTTTTATATGCCAGGCACTGCTGGGCACT
GGAAATATAAAAGTAAGCAAAAATGAAAAACTATCCTGTCCTCCTGAGGCTTAGCATCTAAGGGAGACAGGCATTAGTCAACCCCGTGTG
GCTGTGAATCAGCCATGATGCTGAGTGCTACAAGAGAGGACTGTGCGGCTGGGAGGGCTTATAACAGGATTTGACCTAGTTAGGGAAGAT
CTGAGGAAGTGATGAAAGAATGGAAATCAATATGTAAGAGCTCACAAGTCAGAGTGAGATGTTTCTTCCTATACTGCCTGCTTCTAATGA
GCATCCACTTCATTGAACCACCTCTTCATTGAGCCAAACCTACCATACAGGGATACATTCTCTGGAGGAAAGTTGAGCAACTATTGCATT
TGGGACATTAGAGTATGGGTGGGCTGACAGGTATGTGTATGTTTATTATCCAAGACAGCCAAGGTGTTTATCCTGTTACAACATCCCAGA
GGACAGAGGCTCTTATTTGTGACTCTTTTTTCTTACCTGTAACACCAGAGGCATAACGTACATCATAATGCTGCATCTTGTTGACGCTTC
AATGCTCACAATTCAAAGGTGATTTCTGAAGCACTTTGTTACACTGGGGACAGCTCCTAAATCCTCCCACTCTTTTTTTGCCTCACCTTG
GAGTCTTGGGCTCTGTTGATCACTGACTCTGCCAGGTCTTTCAGCAGGCAAGACAGCTCAGTTAAATTGAGTTTGGACTCCACTGTAGTG
CATGCATGAGACAGCACCCCCAATCCCCAACACCCACACACAAACTTTAAATATTTGTAACAGAATTGTTACCATTAATATTGCTTAAAG
GCTAACACATTAGCCAGAACCTAGATGTCTTCTGGAAATTTTTTATTGCAATGTTACTTCATCTACATAAAGTTGTCCAATCACTGAAAC

>In-frame_ENST00000356554_ENST00000369466_TCGA-13-0760-01A_MAN1A2_chr1_117963271_+_TTF2_chr1_117622190_length(amino acids)=880AA_start in transcript=735_stop in transcript=3377
MTTPALLPLSGRRIPPLNLGPPSFPHHRATLRLSEKFILLLILSAFITLCFGAFFFLPDSSKHKRFDLGLEDVLIPHVDAGKGAKNPGVF
LIHGPDEHRHREEEERLRNKIRADHEKALEEAKEKLRKSREEIRAEIQTEKNKVVQEMKIKENKPLPPVPIPNLVGIRGGDPEDNDIREK
REKIKEMMKHAWDNYRTYGWGHNELRPIARKGHSPNIFGSSQMGATIVDALDTLYIMGLHDEFLDGQRWIEDNLDFSVNSEVSVFEVNIR
FIGGLLAAYYLSGEEVPLLLHQKQALAWLLWRESQKPQGGILADDMGLGKTLTMIALILTQKNQEKKEEKEKSTALTWLSKDDSCDFTSH
GTLIICPASLIHHWKNEVEKRVNSNKLRVYLYHGPNRDSRARVLSTYDIVITTYSLVAKEIPTNKQEAEIPGANLNVEGTSTPLLRIAWA
RIILDEAHNVKNPRVQTSIAVCKLQACARWAVTGTPIQNNLLDMYSLLKFLRCSPFDEFNLWRSQVDNGSKKGGERLSILTKSLLLRRTK
DQLDSTGRPLVILPQRKFQLHHLKLSEDEETVYNVFFARSRSALQSYLKRHESRGNQSGRSPNNPFSRVALEFGSEEPRHSEAADSPRSS
TVHILSQLLRLRQCCCHLSLLKSALDPMELKGEGLVLSLEEQLSALTLSELRDSEPSSTVSLNGTFFKMELFEGMRESTKISSLLAELEA
IQRNSASQKSVIVSQWTNMLKVVALHLKKHGLTYATIDGSVNPKQRMDLVEAFNHSRGPQVMLISLLAGGVGLNLTGGNHLFLLDMHWNP

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Fusion Gene PPI Analysis for MAN1A2-TTF2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for MAN1A2-TTF2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for MAN1A2-TTF2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource