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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:MAP3K7-DCTN4 (FusionGDB2 ID:51083) |
Fusion Gene Summary for MAP3K7-DCTN4 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: MAP3K7-DCTN4 | Fusion gene ID: 51083 | Hgene | Tgene | Gene symbol | MAP3K7 | DCTN4 | Gene ID | 6885 | 51164 |
| Gene name | mitogen-activated protein kinase kinase kinase 7 | dynactin subunit 4 | |
| Synonyms | CSCF|FMD2|MEKK7|TAK1|TGF1a | DYN4|P62 | |
| Cytomap | 6q15 | 5q33.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | mitogen-activated protein kinase kinase kinase 7TGF-beta activated kinase 1transforming growth factor-beta-activated kinase 1 | dynactin subunit 4dynactin 4 (p62)dynactin p62 subunitdynactin subunit p62 | |
| Modification date | 20200313 | 20200313 | |
| UniProtAcc | O43318 | Q9UJW0 | |
| Ensembl transtripts involved in fusion gene | ENST00000369325, ENST00000369327, ENST00000369332, ENST00000369329, ENST00000479630, ENST00000369320, | ENST00000447998, ENST00000424236, ENST00000446090, ENST00000521093, | |
| Fusion gene scores | * DoF score | 9 X 8 X 6=432 | 5 X 7 X 4=140 |
| # samples | 10 | 7 | |
| ** MAII score | log2(10/432*10)=-2.11103131238874 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(7/140*10)=-1 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: MAP3K7 [Title/Abstract] AND DCTN4 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | MAP3K7(91256976)-DCTN4(150110302), # samples:1 | ||
| Anticipated loss of major functional domain due to fusion event. | MAP3K7-DCTN4 seems lost the major protein functional domain in Hgene partner, which is a kinase due to the frame-shifted ORF. MAP3K7-DCTN4 seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF. MAP3K7-DCTN4 seems lost the major protein functional domain in Hgene partner, which is a epigenetic factor due to the frame-shifted ORF. MAP3K7-DCTN4 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | MAP3K7 | GO:0000186 | activation of MAPKK activity | 8663074|9079627 |
| Hgene | MAP3K7 | GO:0000187 | activation of MAPK activity | 9079627 |
| Hgene | MAP3K7 | GO:0007252 | I-kappaB phosphorylation | 11460167 |
| Hgene | MAP3K7 | GO:0007254 | JNK cascade | 9079627 |
| Hgene | MAP3K7 | GO:0043507 | positive regulation of JUN kinase activity | 11460167 |
| Hgene | MAP3K7 | GO:0043966 | histone H3 acetylation | 18838386 |
| Hgene | MAP3K7 | GO:0051403 | stress-activated MAPK cascade | 9079627 |
| Fusion gene breakpoints across MAP3K7 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
| Fusion gene breakpoints across DCTN4 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | BRCA | TCGA-B6-A401 | MAP3K7 | chr6 | 91256976 | - | DCTN4 | chr5 | 150110302 | - |
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Fusion Gene ORF analysis for MAP3K7-DCTN4 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000369325 | ENST00000447998 | MAP3K7 | chr6 | 91256976 | - | DCTN4 | chr5 | 150110302 | - |
| In-frame | ENST00000369325 | ENST00000424236 | MAP3K7 | chr6 | 91256976 | - | DCTN4 | chr5 | 150110302 | - |
| In-frame | ENST00000369325 | ENST00000446090 | MAP3K7 | chr6 | 91256976 | - | DCTN4 | chr5 | 150110302 | - |
| 5CDS-intron | ENST00000369325 | ENST00000521093 | MAP3K7 | chr6 | 91256976 | - | DCTN4 | chr5 | 150110302 | - |
| In-frame | ENST00000369327 | ENST00000447998 | MAP3K7 | chr6 | 91256976 | - | DCTN4 | chr5 | 150110302 | - |
| In-frame | ENST00000369327 | ENST00000424236 | MAP3K7 | chr6 | 91256976 | - | DCTN4 | chr5 | 150110302 | - |
| In-frame | ENST00000369327 | ENST00000446090 | MAP3K7 | chr6 | 91256976 | - | DCTN4 | chr5 | 150110302 | - |
| 5CDS-intron | ENST00000369327 | ENST00000521093 | MAP3K7 | chr6 | 91256976 | - | DCTN4 | chr5 | 150110302 | - |
| In-frame | ENST00000369332 | ENST00000447998 | MAP3K7 | chr6 | 91256976 | - | DCTN4 | chr5 | 150110302 | - |
| In-frame | ENST00000369332 | ENST00000424236 | MAP3K7 | chr6 | 91256976 | - | DCTN4 | chr5 | 150110302 | - |
| In-frame | ENST00000369332 | ENST00000446090 | MAP3K7 | chr6 | 91256976 | - | DCTN4 | chr5 | 150110302 | - |
| 5CDS-intron | ENST00000369332 | ENST00000521093 | MAP3K7 | chr6 | 91256976 | - | DCTN4 | chr5 | 150110302 | - |
| In-frame | ENST00000369329 | ENST00000447998 | MAP3K7 | chr6 | 91256976 | - | DCTN4 | chr5 | 150110302 | - |
| In-frame | ENST00000369329 | ENST00000424236 | MAP3K7 | chr6 | 91256976 | - | DCTN4 | chr5 | 150110302 | - |
| In-frame | ENST00000369329 | ENST00000446090 | MAP3K7 | chr6 | 91256976 | - | DCTN4 | chr5 | 150110302 | - |
| 5CDS-intron | ENST00000369329 | ENST00000521093 | MAP3K7 | chr6 | 91256976 | - | DCTN4 | chr5 | 150110302 | - |
| intron-3CDS | ENST00000479630 | ENST00000447998 | MAP3K7 | chr6 | 91256976 | - | DCTN4 | chr5 | 150110302 | - |
| intron-3CDS | ENST00000479630 | ENST00000424236 | MAP3K7 | chr6 | 91256976 | - | DCTN4 | chr5 | 150110302 | - |
| intron-3CDS | ENST00000479630 | ENST00000446090 | MAP3K7 | chr6 | 91256976 | - | DCTN4 | chr5 | 150110302 | - |
| intron-intron | ENST00000479630 | ENST00000521093 | MAP3K7 | chr6 | 91256976 | - | DCTN4 | chr5 | 150110302 | - |
| Frame-shift | ENST00000369320 | ENST00000447998 | MAP3K7 | chr6 | 91256976 | - | DCTN4 | chr5 | 150110302 | - |
| Frame-shift | ENST00000369320 | ENST00000424236 | MAP3K7 | chr6 | 91256976 | - | DCTN4 | chr5 | 150110302 | - |
| Frame-shift | ENST00000369320 | ENST00000446090 | MAP3K7 | chr6 | 91256976 | - | DCTN4 | chr5 | 150110302 | - |
| 5CDS-intron | ENST00000369320 | ENST00000521093 | MAP3K7 | chr6 | 91256976 | - | DCTN4 | chr5 | 150110302 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000369325 | MAP3K7 | chr6 | 91256976 | - | ENST00000447998 | DCTN4 | chr5 | 150110302 | - | 4578 | 1210 | 0 | 1868 | 622 |
| ENST00000369325 | MAP3K7 | chr6 | 91256976 | - | ENST00000424236 | DCTN4 | chr5 | 150110302 | - | 4270 | 1210 | 0 | 1868 | 622 |
| ENST00000369325 | MAP3K7 | chr6 | 91256976 | - | ENST00000446090 | DCTN4 | chr5 | 150110302 | - | 2160 | 1210 | 0 | 1868 | 622 |
| ENST00000369327 | MAP3K7 | chr6 | 91256976 | - | ENST00000447998 | DCTN4 | chr5 | 150110302 | - | 4584 | 1216 | 6 | 1874 | 622 |
| ENST00000369327 | MAP3K7 | chr6 | 91256976 | - | ENST00000424236 | DCTN4 | chr5 | 150110302 | - | 4276 | 1216 | 6 | 1874 | 622 |
| ENST00000369327 | MAP3K7 | chr6 | 91256976 | - | ENST00000446090 | DCTN4 | chr5 | 150110302 | - | 2166 | 1216 | 6 | 1874 | 622 |
| ENST00000369332 | MAP3K7 | chr6 | 91256976 | - | ENST00000447998 | DCTN4 | chr5 | 150110302 | - | 4740 | 1372 | 114 | 2030 | 638 |
| ENST00000369332 | MAP3K7 | chr6 | 91256976 | - | ENST00000424236 | DCTN4 | chr5 | 150110302 | - | 4432 | 1372 | 114 | 2030 | 638 |
| ENST00000369332 | MAP3K7 | chr6 | 91256976 | - | ENST00000446090 | DCTN4 | chr5 | 150110302 | - | 2322 | 1372 | 114 | 2030 | 638 |
| ENST00000369329 | MAP3K7 | chr6 | 91256976 | - | ENST00000447998 | DCTN4 | chr5 | 150110302 | - | 4740 | 1372 | 114 | 2030 | 638 |
| ENST00000369329 | MAP3K7 | chr6 | 91256976 | - | ENST00000424236 | DCTN4 | chr5 | 150110302 | - | 4432 | 1372 | 114 | 2030 | 638 |
| ENST00000369329 | MAP3K7 | chr6 | 91256976 | - | ENST00000446090 | DCTN4 | chr5 | 150110302 | - | 2322 | 1372 | 114 | 2030 | 638 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000369325 | ENST00000447998 | MAP3K7 | chr6 | 91256976 | - | DCTN4 | chr5 | 150110302 | - | 0.000197853 | 0.9998022 |
| ENST00000369325 | ENST00000424236 | MAP3K7 | chr6 | 91256976 | - | DCTN4 | chr5 | 150110302 | - | 0.000196079 | 0.99980396 |
| ENST00000369325 | ENST00000446090 | MAP3K7 | chr6 | 91256976 | - | DCTN4 | chr5 | 150110302 | - | 0.000710487 | 0.9992895 |
| ENST00000369327 | ENST00000447998 | MAP3K7 | chr6 | 91256976 | - | DCTN4 | chr5 | 150110302 | - | 0.000199569 | 0.9998005 |
| ENST00000369327 | ENST00000424236 | MAP3K7 | chr6 | 91256976 | - | DCTN4 | chr5 | 150110302 | - | 0.000197377 | 0.99980265 |
| ENST00000369327 | ENST00000446090 | MAP3K7 | chr6 | 91256976 | - | DCTN4 | chr5 | 150110302 | - | 0.00071239 | 0.99928766 |
| ENST00000369332 | ENST00000447998 | MAP3K7 | chr6 | 91256976 | - | DCTN4 | chr5 | 150110302 | - | 0.000203163 | 0.9997968 |
| ENST00000369332 | ENST00000424236 | MAP3K7 | chr6 | 91256976 | - | DCTN4 | chr5 | 150110302 | - | 0.000204818 | 0.99979526 |
| ENST00000369332 | ENST00000446090 | MAP3K7 | chr6 | 91256976 | - | DCTN4 | chr5 | 150110302 | - | 0.000682414 | 0.99931765 |
| ENST00000369329 | ENST00000447998 | MAP3K7 | chr6 | 91256976 | - | DCTN4 | chr5 | 150110302 | - | 0.000203163 | 0.9997968 |
| ENST00000369329 | ENST00000424236 | MAP3K7 | chr6 | 91256976 | - | DCTN4 | chr5 | 150110302 | - | 0.000204818 | 0.99979526 |
| ENST00000369329 | ENST00000446090 | MAP3K7 | chr6 | 91256976 | - | DCTN4 | chr5 | 150110302 | - | 0.000682414 | 0.99931765 |
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Fusion Genomic Features for MAP3K7-DCTN4 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for MAP3K7-DCTN4 |
| Go to FGviewer for the breakpoints of chr6:91256976-chr5:150110302 - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| MAP3K7 | DCTN4 |
| FUNCTION: Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Mediates signal transduction of TRAF6, various cytokines including interleukin-1 (IL-1), transforming growth factor-beta (TGFB), TGFB-related factors like BMP2 and BMP4, toll-like receptors (TLR), tumor necrosis factor receptor CD40 and B-cell receptor (BCR). Ceramides are also able to activate MAP3K7/TAK1. Once activated, acts as an upstream activator of the MKK/JNK signal transduction cascade and the p38 MAPK signal transduction cascade through the phosphorylation and activation of several MAP kinase kinases like MAP2K1/MEK1, MAP2K3/MKK3, MAP2K6/MKK6 and MAP2K7/MKK7. These MAP2Ks in turn activate p38 MAPKs, c-jun N-terminal kinases (JNKs) and I-kappa-B kinase complex (IKK). Both p38 MAPK and JNK pathways control the transcription factors activator protein-1 (AP-1), while nuclear factor-kappa B is activated by IKK. MAP3K7 activates also IKBKB and MAPK8/JNK1 in response to TRAF6 signaling and mediates BMP2-induced apoptosis. In osmotic stress signaling, plays a major role in the activation of MAPK8/JNK1, but not that of NF-kappa-B. Promotes TRIM5 capsid-specific restriction activity. Phosphorylates RIPK1 at 'Ser-321' which positively regulates RIPK1 interaction with RIPK3 to promote necroptosis but negatively regulates RIPK1 kinase activity and its interaction with FADD to mediate apoptosis (By similarity). {ECO:0000250|UniProtKB:Q62073, ECO:0000269|PubMed:10094049, ECO:0000269|PubMed:11460167, ECO:0000269|PubMed:12589052, ECO:0000269|PubMed:16845370, ECO:0000269|PubMed:16893890, ECO:0000269|PubMed:21512573, ECO:0000269|PubMed:8663074, ECO:0000269|PubMed:9079627}. | FUNCTION: Could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. Could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | MAP3K7 | chr6:91256976 | chr5:150110302 | ENST00000369325 | - | 11 | 16 | 8_14 | 403.3333333333333 | 519.0 | Compositional bias | Note=Poly-Ser |
| Hgene | MAP3K7 | chr6:91256976 | chr5:150110302 | ENST00000369327 | - | 11 | 15 | 8_14 | 403.3333333333333 | 492.0 | Compositional bias | Note=Poly-Ser |
| Hgene | MAP3K7 | chr6:91256976 | chr5:150110302 | ENST00000369329 | - | 11 | 17 | 8_14 | 403.3333333333333 | 607.0 | Compositional bias | Note=Poly-Ser |
| Hgene | MAP3K7 | chr6:91256976 | chr5:150110302 | ENST00000369332 | - | 11 | 16 | 8_14 | 403.3333333333333 | 580.0 | Compositional bias | Note=Poly-Ser |
| Hgene | MAP3K7 | chr6:91256976 | chr5:150110302 | ENST00000369325 | - | 11 | 16 | 36_291 | 403.3333333333333 | 519.0 | Domain | Protein kinase |
| Hgene | MAP3K7 | chr6:91256976 | chr5:150110302 | ENST00000369327 | - | 11 | 15 | 36_291 | 403.3333333333333 | 492.0 | Domain | Protein kinase |
| Hgene | MAP3K7 | chr6:91256976 | chr5:150110302 | ENST00000369329 | - | 11 | 17 | 36_291 | 403.3333333333333 | 607.0 | Domain | Protein kinase |
| Hgene | MAP3K7 | chr6:91256976 | chr5:150110302 | ENST00000369332 | - | 11 | 16 | 36_291 | 403.3333333333333 | 580.0 | Domain | Protein kinase |
| Hgene | MAP3K7 | chr6:91256976 | chr5:150110302 | ENST00000369325 | - | 11 | 16 | 42_50 | 403.3333333333333 | 519.0 | Nucleotide binding | ATP |
| Hgene | MAP3K7 | chr6:91256976 | chr5:150110302 | ENST00000369327 | - | 11 | 15 | 42_50 | 403.3333333333333 | 492.0 | Nucleotide binding | ATP |
| Hgene | MAP3K7 | chr6:91256976 | chr5:150110302 | ENST00000369329 | - | 11 | 17 | 42_50 | 403.3333333333333 | 607.0 | Nucleotide binding | ATP |
| Hgene | MAP3K7 | chr6:91256976 | chr5:150110302 | ENST00000369332 | - | 11 | 16 | 42_50 | 403.3333333333333 | 580.0 | Nucleotide binding | ATP |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | DCTN4 | chr6:91256976 | chr5:150110302 | ENST00000424236 | 6 | 13 | 152_172 | 184.33333333333334 | 404.0 | Coiled coil | Ontology_term=ECO:0000255 | |
| Tgene | DCTN4 | chr6:91256976 | chr5:150110302 | ENST00000446090 | 7 | 14 | 152_172 | 248.33333333333334 | 468.0 | Coiled coil | Ontology_term=ECO:0000255 | |
| Tgene | DCTN4 | chr6:91256976 | chr5:150110302 | ENST00000447998 | 6 | 13 | 152_172 | 241.33333333333334 | 461.0 | Coiled coil | Ontology_term=ECO:0000255 |
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Fusion Gene Sequence for MAP3K7-DCTN4 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >In-frame_ENST00000369325_ENST00000447998_TCGA-B6-A401_MAP3K7_chr6_91256976_-_DCTN4_chr5_150110302_length(transcript)=4578nt_BP=1210nt ATGTCTACAGCCTCTGCCGCCTCCTCCTCCTCCTCGTCTTCGGCCGGTGAGATGATCGAAGCCCCTTCCCAGGTCCTCAACTTTGAAGAG ATCGACTACAAGGAGATCGAGGTGGAAGAGGTTGTTGGAAGAGGAGCCTTTGGAGTTGTTTGCAAAGCTAAGTGGAGAGCAAAAGATGTT GCTATTAAACAAATAGAAAGTGAATCTGAGAGGAAAGCGTTTATTGTAGAGCTTCGGCAGTTATCCCGTGTGAACCATCCTAATATTGTA AAGCTTTATGGAGCCTGCTTGAATCCAGTGTGTCTTGTGATGGAATATGCTGAAGGGGGCTCTTTATATAATGTGCTGCATGGTGCTGAA CCATTGCCATATTATACTGCTGCCCACGCAATGAGTTGGTGTTTACAGTGTTCCCAAGGAGTGGCTTATCTTCACAGCATGCAACCCAAA GCGCTAATTCACAGGGACCTGAAACCACCAAACTTACTGCTGGTTGCAGGGGGGACAGTTCTAAAAATTTGTGATTTTGGTACAGCCTGT GACATTCAGACACACATGACCAATAACAAGGGGAGTGCTGCTTGGATGGCACCTGAAGTTTTTGAAGGTAGTAATTACAGTGAAAAATGT GACGTCTTCAGCTGGGGTATTATTCTTTGGGAAGTGATAACGCGTCGGAAACCCTTTGATGAGATTGGTGGCCCAGCTTTCCGAATCATG TGGGCTGTTCATAATGGTACTCGACCACCACTGATAAAAAATTTACCTAAGCCCATTGAGAGCCTGATGACTCGTTGTTGGTCTAAAGAT CCTTCCCAGCGCCCTTCAATGGAGGAAATTGTGAAAATAATGACTCACTTGATGCGGTACTTTCCAGGAGCAGATGAGCCATTACAGTAT CCTTGTCAGTATTCAGATGAAGGACAGAGCAACTCTGCCACCAGTACAGGCTCATTCATGGACATTGCTTCTACAAATACGAGTAACAAA AGTGACACTAATATGGAGCAAGTTCCTGCCACAAATGATACTATTAAGCGCTTAGAATCAAAATTGTTGAAAAATCAGGCAAAGCAACAG AGTGAATCTGGACGTTTAAGCTTGGGAGCCTCCCGTGGGAGCAGTGTGGAGAGCTTGCCCCCAACCTCTGAGGGCAAGAGGATGAGTGCT GACATGTCTGAAATAGAAGCTAGGATCGCCGCAACCACAGTAACAACCCTTCAGCAGCGTCTGTTACAGCCTGACTTCCAGCCAGTCTGT GCTTCACAGCTCTATCCTCGCCACAAACATCTTCTGATCAAACGGTCCCTGCGCTGCCGTAAATGTGAACATAATTTGAGCAAGCCAGAA TTTAACCCAACGTCAATCAAATTCAAAATCCAGCTGGTCGCTGTCAATTATATTCCAGAAGTGAGAATCATGTCAATTCCCAACCTTCGC TACATGAAGGAGAGCCAGGTCCTCCTGACTCTTACAAATCCAGTTGAGAACCTCACCCATGTGACTCTCTTCGAGTGTGAGGAGGGGGAC CCTGATGATATCAACAGCACTGCTAAGGTGGTGGTGCCTCCCAAAGAGCTCGTTTTAGCTGGCAAGGATGCAGCAGCAGAGTACGATGAG TTGGCAGAACCTCAAGACTTTCAGGACGATCCTGACATTATAGCCTTCAGAAAGGCCAACAAAGTGGGTATTTTCATCAAAGTTACACCA CAGCGTGAGGAGGGTGAAGTGACCGTGTGCTTCAAGATGAAGCATGATTTTAAAAACCTGGCAGCCCCCATTCGCCCCATTGAAGAAAGT GACCAGGGAACAGAAGTCATCTGGCTCACCCAGCATGTGGAACTTAGCTTGGGCCCACTTCTTCCTTAAAAGGTTCCACTGGAGGGCAGA TCCCAAAGGACAGTATCACCGTAAACCTGCGTTAAAATGTGGAAGCTGCTGCTTCATTAGGCCTTGTTTATAACGATGTACCCATGCACT ACGGAATTCTATTGCTAAGAAAGTGGGAGCATAGGCAAGGCATTGGGAACACAGGGTAGCTGCTGTTGCTCTTGCTCTCACCCCTGTTGA CACCAGTAAGTCTGTGTCTCCCTCACTGAACCCTGCACGTTGAGTAACAGCAGCATAATTCCATCCTAGGAAAGGGGATGGGTGTTCCTT GGAATGGCATTGTATTTACCACCTGAGAAACTCTGTACTGTCTCTTGATCTGATCTCACTAAGGATCACAATGTCACAGATGAAACTTAA ATGATAACCCAAAGGTAGACCTGCTGTTAATGATCCAGCATTGGTCACAATGTACCAACTGCTTTCTGCATTCCGTTAAATATCATCTAA CAGTCTAAAACATATCCCTTCATTGCCATAATGGCTGCCATTTTGCCATAGATTTCCATATAACTGAAAAACTGAATTGTCACTTTATCT TTAGTATCATGATGATTGGAAAAACCTGTGAAGTTGTTAAGGCACTCTCATTTGCCCTCTTTTTCTAAGTGAATACAGGACACGTATTAG TTGTTCTTAATTTTTTTCCCAGTAAAATATGGATCTTTTAAGAAGAATTTGAGAAGCAAACAATTACATGTCATGTCAAGGGGGTAGCAG ATTCCATTCGTTTTCAATATTGCCACAATACCCAGGGATTAATGCTGCCACAGGGGGGCAATCTTTATTTGTCTTACTTCCTACCCCTTC CCTGTTCTGCCTCTTTAACTCAGTTAAGTTGTTCTGTTTGGGACCTGGAAAAGAACCCAAAGAAAACCTGAGTGGACAGGTTCATTTCTG GAATGCAGAAAACATTTTAAAGGCTAGATTTTTAGAATATTCTCAACTAGCATTCTTTCCATTGATTTGAAGGGGAAATTAACTATTATA ATCTCTTGAATCCAAAACTGGATATTAAGAACTTTCCCCCTTACTAAGTTTAAGACTTTTGTCATGTGGTGAGTCAAATAAGACCATTTT GATTGTAAACCATAAAATAGTTCAGCAAGTAGCCCACAGTTCTGGCCTAACAGCAGACTTGCTGTTTTCACTTGGTATCCTGGAGTTGGG TTGCTAACCTTAATTTCTATGATGTTTTCTAAAATGAAACTTGATAAAGTAGACCACCAGCTGCACCGTGTTTTCTGTAAAAGTATTGTT AGTAAGTGGCCAAGAGACTTGAGGAAAATACAGATTTTTTGTTTACCTTGGTCTTGTTTTAAGTCTTAAAAAATTAAAGATAACATTATA ATGTAGAATACAGATGGGACATAGTCCTTGTAAGCTTCCCTTGAAAATGTTTTAAATATTTAGGAAGCTTTTAAAAGACACTAAATTGTA CTCTAAAAGACACTAAATTGTACTAATTGTACAAAGGTCAAGCCAATTTTATGAAACAGTCCTACAGAGTAATATATGTGATGCAGTGTA AGAAGGAAAATACTCATCTCTAACATTATGGTAATAACATTTAGCCTCTTAGGAGTTGGAGCAGGGGGATGGGTAATTACAGATTTGCAG ACTATAGAAAGAGTTTCATTTTTTTGTGACCCCACAGAGTCTCAAATTTTTATTTCACTACCTGCTAGAGCCTACTGTGAAATCACTGCT CCATATTTGCCAGTGGAGGAAATGGGCATAGAGTAGAGAATAGCTTCATATGTTTACACGTTTGCATAGACTACACACATGTCATGCGTT TATGGCAGGTAGCTGGTATTTATTCCCCAAAGTAATAATGTTGAAGTATGGGTCTCATCATTCCCATACACAGAAACACAAAACACTTTG ATCATAAACTTTTTTCTTCAGAAGCCAAACTAACTTGCAGAATAATAGAGCCACTGGTTTAATGTTTCCTCAAGATAGGTTTTAGTGTAA GCTAGTATTCTGTGTGTTCGTAGAAATGATTCAATACCTGCAGCTGGTGAATTAGGAATTGTATTTGTTGCCTTTTTTATATTAGATGAG GTGCAAAAATTTTAATGCTAGTCAGTATGCACCACCACAGGAAAGTTAGATCCCATTAGCACTTGAAACTACAGCTTTGGAAACTTAGGC TAAGTTAATTTGGATTTGTTACTTGATTCACCTACTGACCTTTTCTTTTGTTTGAAGTGCTTATCAGCATAATGAGCTAAGTGTCATGCA TATTTGTGAAGAAACACCCTTTTTGGTCCCTTTTGGGACAGAGAGGTACTCCTTGATCTTTATGAATGACAGGTTACTGTTTTGCCTTAT TGCTTAACTTAATGTAGTGAAATAAAGCAGACAAAGCTTGAGCGTGTCTTTTGTTTGCTCTCATGTAGATACTAAGTAGCATGGCTCAGA GCCAAAAGACAAGCGTGAAGTTAAGAGAGTTGGCTAAGAGAGTTGGTGGGGCATGCTCCCTTCCATTCCTTAAATGAAGTAATCTAAAAT CTCTTAGCAGGTTAGTTCACCATAATATATAAGTAGATGTTGCTTTGAGCTTCTTATATACATATTCACAGAACCATTATATAAATGTTG >In-frame_ENST00000369325_ENST00000447998_TCGA-B6-A401_MAP3K7_chr6_91256976_-_DCTN4_chr5_150110302_length(amino acids)=622AA_start in transcript=0_stop in transcript=1868 MSTASAASSSSSSSAGEMIEAPSQVLNFEEIDYKEIEVEEVVGRGAFGVVCKAKWRAKDVAIKQIESESERKAFIVELRQLSRVNHPNIV KLYGACLNPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDFGTAC DIQTHMTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFRIMWAVHNGTRPPLIKNLPKPIESLMTRCWSKD PSQRPSMEEIVKIMTHLMRYFPGADEPLQYPCQYSDEGQSNSATSTGSFMDIASTNTSNKSDTNMEQVPATNDTIKRLESKLLKNQAKQQ SESGRLSLGASRGSSVESLPPTSEGKRMSADMSEIEARIAATTVTTLQQRLLQPDFQPVCASQLYPRHKHLLIKRSLRCRKCEHNLSKPE FNPTSIKFKIQLVAVNYIPEVRIMSIPNLRYMKESQVLLTLTNPVENLTHVTLFECEEGDPDDINSTAKVVVPPKELVLAGKDAAAEYDE -------------------------------------------------------------- >In-frame_ENST00000369325_ENST00000424236_TCGA-B6-A401_MAP3K7_chr6_91256976_-_DCTN4_chr5_150110302_length(transcript)=4270nt_BP=1210nt ATGTCTACAGCCTCTGCCGCCTCCTCCTCCTCCTCGTCTTCGGCCGGTGAGATGATCGAAGCCCCTTCCCAGGTCCTCAACTTTGAAGAG ATCGACTACAAGGAGATCGAGGTGGAAGAGGTTGTTGGAAGAGGAGCCTTTGGAGTTGTTTGCAAAGCTAAGTGGAGAGCAAAAGATGTT GCTATTAAACAAATAGAAAGTGAATCTGAGAGGAAAGCGTTTATTGTAGAGCTTCGGCAGTTATCCCGTGTGAACCATCCTAATATTGTA AAGCTTTATGGAGCCTGCTTGAATCCAGTGTGTCTTGTGATGGAATATGCTGAAGGGGGCTCTTTATATAATGTGCTGCATGGTGCTGAA CCATTGCCATATTATACTGCTGCCCACGCAATGAGTTGGTGTTTACAGTGTTCCCAAGGAGTGGCTTATCTTCACAGCATGCAACCCAAA GCGCTAATTCACAGGGACCTGAAACCACCAAACTTACTGCTGGTTGCAGGGGGGACAGTTCTAAAAATTTGTGATTTTGGTACAGCCTGT GACATTCAGACACACATGACCAATAACAAGGGGAGTGCTGCTTGGATGGCACCTGAAGTTTTTGAAGGTAGTAATTACAGTGAAAAATGT GACGTCTTCAGCTGGGGTATTATTCTTTGGGAAGTGATAACGCGTCGGAAACCCTTTGATGAGATTGGTGGCCCAGCTTTCCGAATCATG TGGGCTGTTCATAATGGTACTCGACCACCACTGATAAAAAATTTACCTAAGCCCATTGAGAGCCTGATGACTCGTTGTTGGTCTAAAGAT CCTTCCCAGCGCCCTTCAATGGAGGAAATTGTGAAAATAATGACTCACTTGATGCGGTACTTTCCAGGAGCAGATGAGCCATTACAGTAT CCTTGTCAGTATTCAGATGAAGGACAGAGCAACTCTGCCACCAGTACAGGCTCATTCATGGACATTGCTTCTACAAATACGAGTAACAAA AGTGACACTAATATGGAGCAAGTTCCTGCCACAAATGATACTATTAAGCGCTTAGAATCAAAATTGTTGAAAAATCAGGCAAAGCAACAG AGTGAATCTGGACGTTTAAGCTTGGGAGCCTCCCGTGGGAGCAGTGTGGAGAGCTTGCCCCCAACCTCTGAGGGCAAGAGGATGAGTGCT GACATGTCTGAAATAGAAGCTAGGATCGCCGCAACCACAGTAACAACCCTTCAGCAGCGTCTGTTACAGCCTGACTTCCAGCCAGTCTGT GCTTCACAGCTCTATCCTCGCCACAAACATCTTCTGATCAAACGGTCCCTGCGCTGCCGTAAATGTGAACATAATTTGAGCAAGCCAGAA TTTAACCCAACGTCAATCAAATTCAAAATCCAGCTGGTCGCTGTCAATTATATTCCAGAAGTGAGAATCATGTCAATTCCCAACCTTCGC TACATGAAGGAGAGCCAGGTCCTCCTGACTCTTACAAATCCAGTTGAGAACCTCACCCATGTGACTCTCTTCGAGTGTGAGGAGGGGGAC CCTGATGATATCAACAGCACTGCTAAGGTGGTGGTGCCTCCCAAAGAGCTCGTTTTAGCTGGCAAGGATGCAGCAGCAGAGTACGATGAG TTGGCAGAACCTCAAGACTTTCAGGACGATCCTGACATTATAGCCTTCAGAAAGGCCAACAAAGTGGGTATTTTCATCAAAGTTACACCA CAGCGTGAGGAGGGTGAAGTGACCGTGTGCTTCAAGATGAAGCATGATTTTAAAAACCTGGCAGCCCCCATTCGCCCCATTGAAGAAAGT GACCAGGGAACAGAAGTCATCTGGCTCACCCAGCATGTGGAACTTAGCTTGGGCCCACTTCTTCCTTAAAAGGTTCCACTGGAGGGCAGA TCCCAAAGGACAGTATCACCGTAAACCTGCGTTAAAATGTGGAAGCTGCTGCTTCATTAGGCCTTGTTTATAACGATGTACCCATGCACT ACGGAATTCTATTGCTAAGAAAGTGGGAGCATAGGCAAGGCATTGGGAACACAGGGTAGCTGCTGTTGCTCTTGCTCTCACCCCTGTTGA CACCAGTAAGTCTGTGTCTCCCTCACTGAACCCTGCACGTTGAGTAACAGCAGCATAATTCCATCCTAGGAAAGGGGATGGGTGTTCCTT GGAATGGCATTGTATTTACCACCTGAGAAACTCTGTACTGTCTCTTGATCTGATCTCACTAAGGATCACAATGTCACAGATGAAACTTAA ATGATAACCCAAAGGTAGACCTGCTGTTAATGATCCAGCATTGGTCACAATGTACCAACTGCTTTCTGCATTCCGTTAAATATCATCTAA CAGTCTAAAACATATCCCTTCATTGCCATAATGGCTGCCATTTTGCCATAGATTTCCATATAACTGAAAAACTGAATTGTCACTTTATCT TTAGTATCATGATGATTGGAAAAACCTGTGAAGTTGTTAAGGCACTCTCATTTGCCCTCTTTTTCTAAGTGAATACAGGACACGTATTAG TTGTTCTTAATTTTTTTCCCAGTAAAATATGGATCTTTTAAGAAGAATTTGAGAAGCAAACAATTACATGTCATGTCAAGGGGGTAGCAG ATTCCATTCGTTTTCAATATTGCCACAATACCCAGGGATTAATGCTGCCACAGGGGGGCAATCTTTATTTGTCTTACTTCCTACCCCTTC CCTGTTCTGCCTCTTTAACTCAGTTAAGTTGTTCTGTTTGGGACCTGGAAAAGAACCCAAAGAAAACCTGAGTGGACAGGTTCATTTCTG GAATGCAGAAAACATTTTAAAGGCTAGATTTTTAGAATATTCTCAACTAGCATTCTTTCCATTGATTTGAAGGGGAAATTAACTATTATA ATCTCTTGAATCCAAAACTGGATATTAAGAACTTTCCCCCTTACTAAGTTTAAGACTTTTGTCATGTGGTGAGTCAAATAAGACCATTTT GATTGTAAACCATAAAATAGTTCAGCAAGTAGCCCACAGTTCTGGCCTAACAGCAGACTTGCTGTTTTCACTTGGTATCCTGGAGTTGGG TTGCTAACCTTAATTTCTATGATGTTTTCTAAAATGAAACTTGATAAAGTAGACCACCAGCTGCACCGTGTTTTCTGTAAAAGTATTGTT AGTAAGTGGCCAAGAGACTTGAGGAAAATACAGATTTTTTGTTTACCTTGGTCTTGTTTTAAGTCTTAAAAAATTAAAGATAACATTATA ATGTAGAATACAGATGGGACATAGTCCTTGTAAGCTTCCCTTGAAAATGTTTTAAATATTTAGGAAGCTTTTAAAAGACACTAAATTGTA CTCTAAAAGACACTAAATTGTACTAATTGTACAAAGGTCAAGCCAATTTTATGAAACAGTCCTACAGAGTAATATATGTGATGCAGTGTA AGAAGGAAAATACTCATCTCTAACATTATGGTAATAACATTTAGCCTCTTAGGAGTTGGAGCAGGGGGATGGGTAATTACAGATTTGCAG ACTATAGAAAGAGTTTCATTTTTTTGTGACCCCACAGAGTCTCAAATTTTTATTTCACTACCTGCTAGAGCCTACTGTGAAATCACTGCT CCATATTTGCCAGTGGAGGAAATGGGCATAGAGTAGAGAATAGCTTCATATGTTTACACGTTTGCATAGACTACACACATGTCATGCGTT TATGGCAGGTAGCTGGTATTTATTCCCCAAAGTAATAATGTTGAAGTATGGGTCTCATCATTCCCATACACAGAAACACAAAACACTTTG ATCATAAACTTTTTTCTTCAGAAGCCAAACTAACTTGCAGAATAATAGAGCCACTGGTTTAATGTTTCCTCAAGATAGGTTTTAGTGTAA GCTAGTATTCTGTGTGTTCGTAGAAATGATTCAATACCTGCAGCTGGTGAATTAGGAATTGTATTTGTTGCCTTTTTTATATTAGATGAG GTGCAAAAATTTTAATGCTAGTCAGTATGCACCACCACAGGAAAGTTAGATCCCATTAGCACTTGAAACTACAGCTTTGGAAACTTAGGC TAAGTTAATTTGGATTTGTTACTTGATTCACCTACTGACCTTTTCTTTTGTTTGAAGTGCTTATCAGCATAATGAGCTAAGTGTCATGCA TATTTGTGAAGAAACACCCTTTTTGGTCCCTTTTGGGACAGAGAGGTACTCCTTGATCTTTATGAATGACAGGTTACTGTTTTGCCTTAT >In-frame_ENST00000369325_ENST00000424236_TCGA-B6-A401_MAP3K7_chr6_91256976_-_DCTN4_chr5_150110302_length(amino acids)=622AA_start in transcript=0_stop in transcript=1868 MSTASAASSSSSSSAGEMIEAPSQVLNFEEIDYKEIEVEEVVGRGAFGVVCKAKWRAKDVAIKQIESESERKAFIVELRQLSRVNHPNIV KLYGACLNPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDFGTAC DIQTHMTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFRIMWAVHNGTRPPLIKNLPKPIESLMTRCWSKD PSQRPSMEEIVKIMTHLMRYFPGADEPLQYPCQYSDEGQSNSATSTGSFMDIASTNTSNKSDTNMEQVPATNDTIKRLESKLLKNQAKQQ SESGRLSLGASRGSSVESLPPTSEGKRMSADMSEIEARIAATTVTTLQQRLLQPDFQPVCASQLYPRHKHLLIKRSLRCRKCEHNLSKPE FNPTSIKFKIQLVAVNYIPEVRIMSIPNLRYMKESQVLLTLTNPVENLTHVTLFECEEGDPDDINSTAKVVVPPKELVLAGKDAAAEYDE -------------------------------------------------------------- >In-frame_ENST00000369325_ENST00000446090_TCGA-B6-A401_MAP3K7_chr6_91256976_-_DCTN4_chr5_150110302_length(transcript)=2160nt_BP=1210nt ATGTCTACAGCCTCTGCCGCCTCCTCCTCCTCCTCGTCTTCGGCCGGTGAGATGATCGAAGCCCCTTCCCAGGTCCTCAACTTTGAAGAG ATCGACTACAAGGAGATCGAGGTGGAAGAGGTTGTTGGAAGAGGAGCCTTTGGAGTTGTTTGCAAAGCTAAGTGGAGAGCAAAAGATGTT GCTATTAAACAAATAGAAAGTGAATCTGAGAGGAAAGCGTTTATTGTAGAGCTTCGGCAGTTATCCCGTGTGAACCATCCTAATATTGTA AAGCTTTATGGAGCCTGCTTGAATCCAGTGTGTCTTGTGATGGAATATGCTGAAGGGGGCTCTTTATATAATGTGCTGCATGGTGCTGAA CCATTGCCATATTATACTGCTGCCCACGCAATGAGTTGGTGTTTACAGTGTTCCCAAGGAGTGGCTTATCTTCACAGCATGCAACCCAAA GCGCTAATTCACAGGGACCTGAAACCACCAAACTTACTGCTGGTTGCAGGGGGGACAGTTCTAAAAATTTGTGATTTTGGTACAGCCTGT GACATTCAGACACACATGACCAATAACAAGGGGAGTGCTGCTTGGATGGCACCTGAAGTTTTTGAAGGTAGTAATTACAGTGAAAAATGT GACGTCTTCAGCTGGGGTATTATTCTTTGGGAAGTGATAACGCGTCGGAAACCCTTTGATGAGATTGGTGGCCCAGCTTTCCGAATCATG TGGGCTGTTCATAATGGTACTCGACCACCACTGATAAAAAATTTACCTAAGCCCATTGAGAGCCTGATGACTCGTTGTTGGTCTAAAGAT CCTTCCCAGCGCCCTTCAATGGAGGAAATTGTGAAAATAATGACTCACTTGATGCGGTACTTTCCAGGAGCAGATGAGCCATTACAGTAT CCTTGTCAGTATTCAGATGAAGGACAGAGCAACTCTGCCACCAGTACAGGCTCATTCATGGACATTGCTTCTACAAATACGAGTAACAAA AGTGACACTAATATGGAGCAAGTTCCTGCCACAAATGATACTATTAAGCGCTTAGAATCAAAATTGTTGAAAAATCAGGCAAAGCAACAG AGTGAATCTGGACGTTTAAGCTTGGGAGCCTCCCGTGGGAGCAGTGTGGAGAGCTTGCCCCCAACCTCTGAGGGCAAGAGGATGAGTGCT GACATGTCTGAAATAGAAGCTAGGATCGCCGCAACCACAGTAACAACCCTTCAGCAGCGTCTGTTACAGCCTGACTTCCAGCCAGTCTGT GCTTCACAGCTCTATCCTCGCCACAAACATCTTCTGATCAAACGGTCCCTGCGCTGCCGTAAATGTGAACATAATTTGAGCAAGCCAGAA TTTAACCCAACGTCAATCAAATTCAAAATCCAGCTGGTCGCTGTCAATTATATTCCAGAAGTGAGAATCATGTCAATTCCCAACCTTCGC TACATGAAGGAGAGCCAGGTCCTCCTGACTCTTACAAATCCAGTTGAGAACCTCACCCATGTGACTCTCTTCGAGTGTGAGGAGGGGGAC CCTGATGATATCAACAGCACTGCTAAGGTGGTGGTGCCTCCCAAAGAGCTCGTTTTAGCTGGCAAGGATGCAGCAGCAGAGTACGATGAG TTGGCAGAACCTCAAGACTTTCAGGACGATCCTGACATTATAGCCTTCAGAAAGGCCAACAAAGTGGGTATTTTCATCAAAGTTACACCA CAGCGTGAGGAGGGTGAAGTGACCGTGTGCTTCAAGATGAAGCATGATTTTAAAAACCTGGCAGCCCCCATTCGCCCCATTGAAGAAAGT GACCAGGGAACAGAAGTCATCTGGCTCACCCAGCATGTGGAACTTAGCTTGGGCCCACTTCTTCCTTAAAAGGTTCCACTGGAGGGCAGA TCCCAAAGGACAGTATCACCGTAAACCTGCGTTAAAATGTGGAAGCTGCTGCTTCATTAGGCCTTGTTTATAACGATGTACCCATGCACT ACGGAATTCTATTGCTAAGAAAGTGGGAGCATAGGCAAGGCATTGGGAACACAGGGTAGCTGCTGTTGCTCTTGCTCTCACCCCTGTTGA CACCAGTAAGTCTGTGTCTCCCTCACTGAACCCTGCACGTTGAGTAACAGCAGCATAATTCCATCCTAGGAAAGGGGATGGGTGTTCCTT >In-frame_ENST00000369325_ENST00000446090_TCGA-B6-A401_MAP3K7_chr6_91256976_-_DCTN4_chr5_150110302_length(amino acids)=622AA_start in transcript=0_stop in transcript=1868 MSTASAASSSSSSSAGEMIEAPSQVLNFEEIDYKEIEVEEVVGRGAFGVVCKAKWRAKDVAIKQIESESERKAFIVELRQLSRVNHPNIV KLYGACLNPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDFGTAC DIQTHMTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFRIMWAVHNGTRPPLIKNLPKPIESLMTRCWSKD PSQRPSMEEIVKIMTHLMRYFPGADEPLQYPCQYSDEGQSNSATSTGSFMDIASTNTSNKSDTNMEQVPATNDTIKRLESKLLKNQAKQQ SESGRLSLGASRGSSVESLPPTSEGKRMSADMSEIEARIAATTVTTLQQRLLQPDFQPVCASQLYPRHKHLLIKRSLRCRKCEHNLSKPE FNPTSIKFKIQLVAVNYIPEVRIMSIPNLRYMKESQVLLTLTNPVENLTHVTLFECEEGDPDDINSTAKVVVPPKELVLAGKDAAAEYDE -------------------------------------------------------------- >In-frame_ENST00000369327_ENST00000447998_TCGA-B6-A401_MAP3K7_chr6_91256976_-_DCTN4_chr5_150110302_length(transcript)=4584nt_BP=1216nt GGGATCATGTCTACAGCCTCTGCCGCCTCCTCCTCCTCCTCGTCTTCGGCCGGTGAGATGATCGAAGCCCCTTCCCAGGTCCTCAACTTT GAAGAGATCGACTACAAGGAGATCGAGGTGGAAGAGGTTGTTGGAAGAGGAGCCTTTGGAGTTGTTTGCAAAGCTAAGTGGAGAGCAAAA GATGTTGCTATTAAACAAATAGAAAGTGAATCTGAGAGGAAAGCGTTTATTGTAGAGCTTCGGCAGTTATCCCGTGTGAACCATCCTAAT ATTGTAAAGCTTTATGGAGCCTGCTTGAATCCAGTGTGTCTTGTGATGGAATATGCTGAAGGGGGCTCTTTATATAATGTGCTGCATGGT GCTGAACCATTGCCATATTATACTGCTGCCCACGCAATGAGTTGGTGTTTACAGTGTTCCCAAGGAGTGGCTTATCTTCACAGCATGCAA CCCAAAGCGCTAATTCACAGGGACCTGAAACCACCAAACTTACTGCTGGTTGCAGGGGGGACAGTTCTAAAAATTTGTGATTTTGGTACA GCCTGTGACATTCAGACACACATGACCAATAACAAGGGGAGTGCTGCTTGGATGGCACCTGAAGTTTTTGAAGGTAGTAATTACAGTGAA AAATGTGACGTCTTCAGCTGGGGTATTATTCTTTGGGAAGTGATAACGCGTCGGAAACCCTTTGATGAGATTGGTGGCCCAGCTTTCCGA ATCATGTGGGCTGTTCATAATGGTACTCGACCACCACTGATAAAAAATTTACCTAAGCCCATTGAGAGCCTGATGACTCGTTGTTGGTCT AAAGATCCTTCCCAGCGCCCTTCAATGGAGGAAATTGTGAAAATAATGACTCACTTGATGCGGTACTTTCCAGGAGCAGATGAGCCATTA CAGTATCCTTGTCAGTATTCAGATGAAGGACAGAGCAACTCTGCCACCAGTACAGGCTCATTCATGGACATTGCTTCTACAAATACGAGT AACAAAAGTGACACTAATATGGAGCAAGTTCCTGCCACAAATGATACTATTAAGCGCTTAGAATCAAAATTGTTGAAAAATCAGGCAAAG CAACAGAGTGAATCTGGACGTTTAAGCTTGGGAGCCTCCCGTGGGAGCAGTGTGGAGAGCTTGCCCCCAACCTCTGAGGGCAAGAGGATG AGTGCTGACATGTCTGAAATAGAAGCTAGGATCGCCGCAACCACAGTAACAACCCTTCAGCAGCGTCTGTTACAGCCTGACTTCCAGCCA GTCTGTGCTTCACAGCTCTATCCTCGCCACAAACATCTTCTGATCAAACGGTCCCTGCGCTGCCGTAAATGTGAACATAATTTGAGCAAG CCAGAATTTAACCCAACGTCAATCAAATTCAAAATCCAGCTGGTCGCTGTCAATTATATTCCAGAAGTGAGAATCATGTCAATTCCCAAC CTTCGCTACATGAAGGAGAGCCAGGTCCTCCTGACTCTTACAAATCCAGTTGAGAACCTCACCCATGTGACTCTCTTCGAGTGTGAGGAG GGGGACCCTGATGATATCAACAGCACTGCTAAGGTGGTGGTGCCTCCCAAAGAGCTCGTTTTAGCTGGCAAGGATGCAGCAGCAGAGTAC GATGAGTTGGCAGAACCTCAAGACTTTCAGGACGATCCTGACATTATAGCCTTCAGAAAGGCCAACAAAGTGGGTATTTTCATCAAAGTT ACACCACAGCGTGAGGAGGGTGAAGTGACCGTGTGCTTCAAGATGAAGCATGATTTTAAAAACCTGGCAGCCCCCATTCGCCCCATTGAA GAAAGTGACCAGGGAACAGAAGTCATCTGGCTCACCCAGCATGTGGAACTTAGCTTGGGCCCACTTCTTCCTTAAAAGGTTCCACTGGAG GGCAGATCCCAAAGGACAGTATCACCGTAAACCTGCGTTAAAATGTGGAAGCTGCTGCTTCATTAGGCCTTGTTTATAACGATGTACCCA TGCACTACGGAATTCTATTGCTAAGAAAGTGGGAGCATAGGCAAGGCATTGGGAACACAGGGTAGCTGCTGTTGCTCTTGCTCTCACCCC TGTTGACACCAGTAAGTCTGTGTCTCCCTCACTGAACCCTGCACGTTGAGTAACAGCAGCATAATTCCATCCTAGGAAAGGGGATGGGTG TTCCTTGGAATGGCATTGTATTTACCACCTGAGAAACTCTGTACTGTCTCTTGATCTGATCTCACTAAGGATCACAATGTCACAGATGAA ACTTAAATGATAACCCAAAGGTAGACCTGCTGTTAATGATCCAGCATTGGTCACAATGTACCAACTGCTTTCTGCATTCCGTTAAATATC ATCTAACAGTCTAAAACATATCCCTTCATTGCCATAATGGCTGCCATTTTGCCATAGATTTCCATATAACTGAAAAACTGAATTGTCACT TTATCTTTAGTATCATGATGATTGGAAAAACCTGTGAAGTTGTTAAGGCACTCTCATTTGCCCTCTTTTTCTAAGTGAATACAGGACACG TATTAGTTGTTCTTAATTTTTTTCCCAGTAAAATATGGATCTTTTAAGAAGAATTTGAGAAGCAAACAATTACATGTCATGTCAAGGGGG TAGCAGATTCCATTCGTTTTCAATATTGCCACAATACCCAGGGATTAATGCTGCCACAGGGGGGCAATCTTTATTTGTCTTACTTCCTAC CCCTTCCCTGTTCTGCCTCTTTAACTCAGTTAAGTTGTTCTGTTTGGGACCTGGAAAAGAACCCAAAGAAAACCTGAGTGGACAGGTTCA TTTCTGGAATGCAGAAAACATTTTAAAGGCTAGATTTTTAGAATATTCTCAACTAGCATTCTTTCCATTGATTTGAAGGGGAAATTAACT ATTATAATCTCTTGAATCCAAAACTGGATATTAAGAACTTTCCCCCTTACTAAGTTTAAGACTTTTGTCATGTGGTGAGTCAAATAAGAC CATTTTGATTGTAAACCATAAAATAGTTCAGCAAGTAGCCCACAGTTCTGGCCTAACAGCAGACTTGCTGTTTTCACTTGGTATCCTGGA GTTGGGTTGCTAACCTTAATTTCTATGATGTTTTCTAAAATGAAACTTGATAAAGTAGACCACCAGCTGCACCGTGTTTTCTGTAAAAGT ATTGTTAGTAAGTGGCCAAGAGACTTGAGGAAAATACAGATTTTTTGTTTACCTTGGTCTTGTTTTAAGTCTTAAAAAATTAAAGATAAC ATTATAATGTAGAATACAGATGGGACATAGTCCTTGTAAGCTTCCCTTGAAAATGTTTTAAATATTTAGGAAGCTTTTAAAAGACACTAA ATTGTACTCTAAAAGACACTAAATTGTACTAATTGTACAAAGGTCAAGCCAATTTTATGAAACAGTCCTACAGAGTAATATATGTGATGC AGTGTAAGAAGGAAAATACTCATCTCTAACATTATGGTAATAACATTTAGCCTCTTAGGAGTTGGAGCAGGGGGATGGGTAATTACAGAT TTGCAGACTATAGAAAGAGTTTCATTTTTTTGTGACCCCACAGAGTCTCAAATTTTTATTTCACTACCTGCTAGAGCCTACTGTGAAATC ACTGCTCCATATTTGCCAGTGGAGGAAATGGGCATAGAGTAGAGAATAGCTTCATATGTTTACACGTTTGCATAGACTACACACATGTCA TGCGTTTATGGCAGGTAGCTGGTATTTATTCCCCAAAGTAATAATGTTGAAGTATGGGTCTCATCATTCCCATACACAGAAACACAAAAC ACTTTGATCATAAACTTTTTTCTTCAGAAGCCAAACTAACTTGCAGAATAATAGAGCCACTGGTTTAATGTTTCCTCAAGATAGGTTTTA GTGTAAGCTAGTATTCTGTGTGTTCGTAGAAATGATTCAATACCTGCAGCTGGTGAATTAGGAATTGTATTTGTTGCCTTTTTTATATTA GATGAGGTGCAAAAATTTTAATGCTAGTCAGTATGCACCACCACAGGAAAGTTAGATCCCATTAGCACTTGAAACTACAGCTTTGGAAAC TTAGGCTAAGTTAATTTGGATTTGTTACTTGATTCACCTACTGACCTTTTCTTTTGTTTGAAGTGCTTATCAGCATAATGAGCTAAGTGT CATGCATATTTGTGAAGAAACACCCTTTTTGGTCCCTTTTGGGACAGAGAGGTACTCCTTGATCTTTATGAATGACAGGTTACTGTTTTG CCTTATTGCTTAACTTAATGTAGTGAAATAAAGCAGACAAAGCTTGAGCGTGTCTTTTGTTTGCTCTCATGTAGATACTAAGTAGCATGG CTCAGAGCCAAAAGACAAGCGTGAAGTTAAGAGAGTTGGCTAAGAGAGTTGGTGGGGCATGCTCCCTTCCATTCCTTAAATGAAGTAATC TAAAATCTCTTAGCAGGTTAGTTCACCATAATATATAAGTAGATGTTGCTTTGAGCTTCTTATATACATATTCACAGAACCATTATATAA >In-frame_ENST00000369327_ENST00000447998_TCGA-B6-A401_MAP3K7_chr6_91256976_-_DCTN4_chr5_150110302_length(amino acids)=622AA_start in transcript=6_stop in transcript=1874 MSTASAASSSSSSSAGEMIEAPSQVLNFEEIDYKEIEVEEVVGRGAFGVVCKAKWRAKDVAIKQIESESERKAFIVELRQLSRVNHPNIV KLYGACLNPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDFGTAC DIQTHMTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFRIMWAVHNGTRPPLIKNLPKPIESLMTRCWSKD PSQRPSMEEIVKIMTHLMRYFPGADEPLQYPCQYSDEGQSNSATSTGSFMDIASTNTSNKSDTNMEQVPATNDTIKRLESKLLKNQAKQQ SESGRLSLGASRGSSVESLPPTSEGKRMSADMSEIEARIAATTVTTLQQRLLQPDFQPVCASQLYPRHKHLLIKRSLRCRKCEHNLSKPE FNPTSIKFKIQLVAVNYIPEVRIMSIPNLRYMKESQVLLTLTNPVENLTHVTLFECEEGDPDDINSTAKVVVPPKELVLAGKDAAAEYDE -------------------------------------------------------------- >In-frame_ENST00000369327_ENST00000424236_TCGA-B6-A401_MAP3K7_chr6_91256976_-_DCTN4_chr5_150110302_length(transcript)=4276nt_BP=1216nt GGGATCATGTCTACAGCCTCTGCCGCCTCCTCCTCCTCCTCGTCTTCGGCCGGTGAGATGATCGAAGCCCCTTCCCAGGTCCTCAACTTT GAAGAGATCGACTACAAGGAGATCGAGGTGGAAGAGGTTGTTGGAAGAGGAGCCTTTGGAGTTGTTTGCAAAGCTAAGTGGAGAGCAAAA GATGTTGCTATTAAACAAATAGAAAGTGAATCTGAGAGGAAAGCGTTTATTGTAGAGCTTCGGCAGTTATCCCGTGTGAACCATCCTAAT ATTGTAAAGCTTTATGGAGCCTGCTTGAATCCAGTGTGTCTTGTGATGGAATATGCTGAAGGGGGCTCTTTATATAATGTGCTGCATGGT GCTGAACCATTGCCATATTATACTGCTGCCCACGCAATGAGTTGGTGTTTACAGTGTTCCCAAGGAGTGGCTTATCTTCACAGCATGCAA CCCAAAGCGCTAATTCACAGGGACCTGAAACCACCAAACTTACTGCTGGTTGCAGGGGGGACAGTTCTAAAAATTTGTGATTTTGGTACA GCCTGTGACATTCAGACACACATGACCAATAACAAGGGGAGTGCTGCTTGGATGGCACCTGAAGTTTTTGAAGGTAGTAATTACAGTGAA AAATGTGACGTCTTCAGCTGGGGTATTATTCTTTGGGAAGTGATAACGCGTCGGAAACCCTTTGATGAGATTGGTGGCCCAGCTTTCCGA ATCATGTGGGCTGTTCATAATGGTACTCGACCACCACTGATAAAAAATTTACCTAAGCCCATTGAGAGCCTGATGACTCGTTGTTGGTCT AAAGATCCTTCCCAGCGCCCTTCAATGGAGGAAATTGTGAAAATAATGACTCACTTGATGCGGTACTTTCCAGGAGCAGATGAGCCATTA CAGTATCCTTGTCAGTATTCAGATGAAGGACAGAGCAACTCTGCCACCAGTACAGGCTCATTCATGGACATTGCTTCTACAAATACGAGT AACAAAAGTGACACTAATATGGAGCAAGTTCCTGCCACAAATGATACTATTAAGCGCTTAGAATCAAAATTGTTGAAAAATCAGGCAAAG CAACAGAGTGAATCTGGACGTTTAAGCTTGGGAGCCTCCCGTGGGAGCAGTGTGGAGAGCTTGCCCCCAACCTCTGAGGGCAAGAGGATG AGTGCTGACATGTCTGAAATAGAAGCTAGGATCGCCGCAACCACAGTAACAACCCTTCAGCAGCGTCTGTTACAGCCTGACTTCCAGCCA GTCTGTGCTTCACAGCTCTATCCTCGCCACAAACATCTTCTGATCAAACGGTCCCTGCGCTGCCGTAAATGTGAACATAATTTGAGCAAG CCAGAATTTAACCCAACGTCAATCAAATTCAAAATCCAGCTGGTCGCTGTCAATTATATTCCAGAAGTGAGAATCATGTCAATTCCCAAC CTTCGCTACATGAAGGAGAGCCAGGTCCTCCTGACTCTTACAAATCCAGTTGAGAACCTCACCCATGTGACTCTCTTCGAGTGTGAGGAG GGGGACCCTGATGATATCAACAGCACTGCTAAGGTGGTGGTGCCTCCCAAAGAGCTCGTTTTAGCTGGCAAGGATGCAGCAGCAGAGTAC GATGAGTTGGCAGAACCTCAAGACTTTCAGGACGATCCTGACATTATAGCCTTCAGAAAGGCCAACAAAGTGGGTATTTTCATCAAAGTT ACACCACAGCGTGAGGAGGGTGAAGTGACCGTGTGCTTCAAGATGAAGCATGATTTTAAAAACCTGGCAGCCCCCATTCGCCCCATTGAA GAAAGTGACCAGGGAACAGAAGTCATCTGGCTCACCCAGCATGTGGAACTTAGCTTGGGCCCACTTCTTCCTTAAAAGGTTCCACTGGAG GGCAGATCCCAAAGGACAGTATCACCGTAAACCTGCGTTAAAATGTGGAAGCTGCTGCTTCATTAGGCCTTGTTTATAACGATGTACCCA TGCACTACGGAATTCTATTGCTAAGAAAGTGGGAGCATAGGCAAGGCATTGGGAACACAGGGTAGCTGCTGTTGCTCTTGCTCTCACCCC TGTTGACACCAGTAAGTCTGTGTCTCCCTCACTGAACCCTGCACGTTGAGTAACAGCAGCATAATTCCATCCTAGGAAAGGGGATGGGTG TTCCTTGGAATGGCATTGTATTTACCACCTGAGAAACTCTGTACTGTCTCTTGATCTGATCTCACTAAGGATCACAATGTCACAGATGAA ACTTAAATGATAACCCAAAGGTAGACCTGCTGTTAATGATCCAGCATTGGTCACAATGTACCAACTGCTTTCTGCATTCCGTTAAATATC ATCTAACAGTCTAAAACATATCCCTTCATTGCCATAATGGCTGCCATTTTGCCATAGATTTCCATATAACTGAAAAACTGAATTGTCACT TTATCTTTAGTATCATGATGATTGGAAAAACCTGTGAAGTTGTTAAGGCACTCTCATTTGCCCTCTTTTTCTAAGTGAATACAGGACACG TATTAGTTGTTCTTAATTTTTTTCCCAGTAAAATATGGATCTTTTAAGAAGAATTTGAGAAGCAAACAATTACATGTCATGTCAAGGGGG TAGCAGATTCCATTCGTTTTCAATATTGCCACAATACCCAGGGATTAATGCTGCCACAGGGGGGCAATCTTTATTTGTCTTACTTCCTAC CCCTTCCCTGTTCTGCCTCTTTAACTCAGTTAAGTTGTTCTGTTTGGGACCTGGAAAAGAACCCAAAGAAAACCTGAGTGGACAGGTTCA TTTCTGGAATGCAGAAAACATTTTAAAGGCTAGATTTTTAGAATATTCTCAACTAGCATTCTTTCCATTGATTTGAAGGGGAAATTAACT ATTATAATCTCTTGAATCCAAAACTGGATATTAAGAACTTTCCCCCTTACTAAGTTTAAGACTTTTGTCATGTGGTGAGTCAAATAAGAC CATTTTGATTGTAAACCATAAAATAGTTCAGCAAGTAGCCCACAGTTCTGGCCTAACAGCAGACTTGCTGTTTTCACTTGGTATCCTGGA GTTGGGTTGCTAACCTTAATTTCTATGATGTTTTCTAAAATGAAACTTGATAAAGTAGACCACCAGCTGCACCGTGTTTTCTGTAAAAGT ATTGTTAGTAAGTGGCCAAGAGACTTGAGGAAAATACAGATTTTTTGTTTACCTTGGTCTTGTTTTAAGTCTTAAAAAATTAAAGATAAC ATTATAATGTAGAATACAGATGGGACATAGTCCTTGTAAGCTTCCCTTGAAAATGTTTTAAATATTTAGGAAGCTTTTAAAAGACACTAA ATTGTACTCTAAAAGACACTAAATTGTACTAATTGTACAAAGGTCAAGCCAATTTTATGAAACAGTCCTACAGAGTAATATATGTGATGC AGTGTAAGAAGGAAAATACTCATCTCTAACATTATGGTAATAACATTTAGCCTCTTAGGAGTTGGAGCAGGGGGATGGGTAATTACAGAT TTGCAGACTATAGAAAGAGTTTCATTTTTTTGTGACCCCACAGAGTCTCAAATTTTTATTTCACTACCTGCTAGAGCCTACTGTGAAATC ACTGCTCCATATTTGCCAGTGGAGGAAATGGGCATAGAGTAGAGAATAGCTTCATATGTTTACACGTTTGCATAGACTACACACATGTCA TGCGTTTATGGCAGGTAGCTGGTATTTATTCCCCAAAGTAATAATGTTGAAGTATGGGTCTCATCATTCCCATACACAGAAACACAAAAC ACTTTGATCATAAACTTTTTTCTTCAGAAGCCAAACTAACTTGCAGAATAATAGAGCCACTGGTTTAATGTTTCCTCAAGATAGGTTTTA GTGTAAGCTAGTATTCTGTGTGTTCGTAGAAATGATTCAATACCTGCAGCTGGTGAATTAGGAATTGTATTTGTTGCCTTTTTTATATTA GATGAGGTGCAAAAATTTTAATGCTAGTCAGTATGCACCACCACAGGAAAGTTAGATCCCATTAGCACTTGAAACTACAGCTTTGGAAAC TTAGGCTAAGTTAATTTGGATTTGTTACTTGATTCACCTACTGACCTTTTCTTTTGTTTGAAGTGCTTATCAGCATAATGAGCTAAGTGT CATGCATATTTGTGAAGAAACACCCTTTTTGGTCCCTTTTGGGACAGAGAGGTACTCCTTGATCTTTATGAATGACAGGTTACTGTTTTG >In-frame_ENST00000369327_ENST00000424236_TCGA-B6-A401_MAP3K7_chr6_91256976_-_DCTN4_chr5_150110302_length(amino acids)=622AA_start in transcript=6_stop in transcript=1874 MSTASAASSSSSSSAGEMIEAPSQVLNFEEIDYKEIEVEEVVGRGAFGVVCKAKWRAKDVAIKQIESESERKAFIVELRQLSRVNHPNIV KLYGACLNPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDFGTAC DIQTHMTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFRIMWAVHNGTRPPLIKNLPKPIESLMTRCWSKD PSQRPSMEEIVKIMTHLMRYFPGADEPLQYPCQYSDEGQSNSATSTGSFMDIASTNTSNKSDTNMEQVPATNDTIKRLESKLLKNQAKQQ SESGRLSLGASRGSSVESLPPTSEGKRMSADMSEIEARIAATTVTTLQQRLLQPDFQPVCASQLYPRHKHLLIKRSLRCRKCEHNLSKPE FNPTSIKFKIQLVAVNYIPEVRIMSIPNLRYMKESQVLLTLTNPVENLTHVTLFECEEGDPDDINSTAKVVVPPKELVLAGKDAAAEYDE -------------------------------------------------------------- >In-frame_ENST00000369327_ENST00000446090_TCGA-B6-A401_MAP3K7_chr6_91256976_-_DCTN4_chr5_150110302_length(transcript)=2166nt_BP=1216nt GGGATCATGTCTACAGCCTCTGCCGCCTCCTCCTCCTCCTCGTCTTCGGCCGGTGAGATGATCGAAGCCCCTTCCCAGGTCCTCAACTTT GAAGAGATCGACTACAAGGAGATCGAGGTGGAAGAGGTTGTTGGAAGAGGAGCCTTTGGAGTTGTTTGCAAAGCTAAGTGGAGAGCAAAA GATGTTGCTATTAAACAAATAGAAAGTGAATCTGAGAGGAAAGCGTTTATTGTAGAGCTTCGGCAGTTATCCCGTGTGAACCATCCTAAT ATTGTAAAGCTTTATGGAGCCTGCTTGAATCCAGTGTGTCTTGTGATGGAATATGCTGAAGGGGGCTCTTTATATAATGTGCTGCATGGT GCTGAACCATTGCCATATTATACTGCTGCCCACGCAATGAGTTGGTGTTTACAGTGTTCCCAAGGAGTGGCTTATCTTCACAGCATGCAA CCCAAAGCGCTAATTCACAGGGACCTGAAACCACCAAACTTACTGCTGGTTGCAGGGGGGACAGTTCTAAAAATTTGTGATTTTGGTACA GCCTGTGACATTCAGACACACATGACCAATAACAAGGGGAGTGCTGCTTGGATGGCACCTGAAGTTTTTGAAGGTAGTAATTACAGTGAA AAATGTGACGTCTTCAGCTGGGGTATTATTCTTTGGGAAGTGATAACGCGTCGGAAACCCTTTGATGAGATTGGTGGCCCAGCTTTCCGA ATCATGTGGGCTGTTCATAATGGTACTCGACCACCACTGATAAAAAATTTACCTAAGCCCATTGAGAGCCTGATGACTCGTTGTTGGTCT AAAGATCCTTCCCAGCGCCCTTCAATGGAGGAAATTGTGAAAATAATGACTCACTTGATGCGGTACTTTCCAGGAGCAGATGAGCCATTA CAGTATCCTTGTCAGTATTCAGATGAAGGACAGAGCAACTCTGCCACCAGTACAGGCTCATTCATGGACATTGCTTCTACAAATACGAGT AACAAAAGTGACACTAATATGGAGCAAGTTCCTGCCACAAATGATACTATTAAGCGCTTAGAATCAAAATTGTTGAAAAATCAGGCAAAG CAACAGAGTGAATCTGGACGTTTAAGCTTGGGAGCCTCCCGTGGGAGCAGTGTGGAGAGCTTGCCCCCAACCTCTGAGGGCAAGAGGATG AGTGCTGACATGTCTGAAATAGAAGCTAGGATCGCCGCAACCACAGTAACAACCCTTCAGCAGCGTCTGTTACAGCCTGACTTCCAGCCA GTCTGTGCTTCACAGCTCTATCCTCGCCACAAACATCTTCTGATCAAACGGTCCCTGCGCTGCCGTAAATGTGAACATAATTTGAGCAAG CCAGAATTTAACCCAACGTCAATCAAATTCAAAATCCAGCTGGTCGCTGTCAATTATATTCCAGAAGTGAGAATCATGTCAATTCCCAAC CTTCGCTACATGAAGGAGAGCCAGGTCCTCCTGACTCTTACAAATCCAGTTGAGAACCTCACCCATGTGACTCTCTTCGAGTGTGAGGAG GGGGACCCTGATGATATCAACAGCACTGCTAAGGTGGTGGTGCCTCCCAAAGAGCTCGTTTTAGCTGGCAAGGATGCAGCAGCAGAGTAC GATGAGTTGGCAGAACCTCAAGACTTTCAGGACGATCCTGACATTATAGCCTTCAGAAAGGCCAACAAAGTGGGTATTTTCATCAAAGTT ACACCACAGCGTGAGGAGGGTGAAGTGACCGTGTGCTTCAAGATGAAGCATGATTTTAAAAACCTGGCAGCCCCCATTCGCCCCATTGAA GAAAGTGACCAGGGAACAGAAGTCATCTGGCTCACCCAGCATGTGGAACTTAGCTTGGGCCCACTTCTTCCTTAAAAGGTTCCACTGGAG GGCAGATCCCAAAGGACAGTATCACCGTAAACCTGCGTTAAAATGTGGAAGCTGCTGCTTCATTAGGCCTTGTTTATAACGATGTACCCA TGCACTACGGAATTCTATTGCTAAGAAAGTGGGAGCATAGGCAAGGCATTGGGAACACAGGGTAGCTGCTGTTGCTCTTGCTCTCACCCC TGTTGACACCAGTAAGTCTGTGTCTCCCTCACTGAACCCTGCACGTTGAGTAACAGCAGCATAATTCCATCCTAGGAAAGGGGATGGGTG >In-frame_ENST00000369327_ENST00000446090_TCGA-B6-A401_MAP3K7_chr6_91256976_-_DCTN4_chr5_150110302_length(amino acids)=622AA_start in transcript=6_stop in transcript=1874 MSTASAASSSSSSSAGEMIEAPSQVLNFEEIDYKEIEVEEVVGRGAFGVVCKAKWRAKDVAIKQIESESERKAFIVELRQLSRVNHPNIV KLYGACLNPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDFGTAC DIQTHMTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFRIMWAVHNGTRPPLIKNLPKPIESLMTRCWSKD PSQRPSMEEIVKIMTHLMRYFPGADEPLQYPCQYSDEGQSNSATSTGSFMDIASTNTSNKSDTNMEQVPATNDTIKRLESKLLKNQAKQQ SESGRLSLGASRGSSVESLPPTSEGKRMSADMSEIEARIAATTVTTLQQRLLQPDFQPVCASQLYPRHKHLLIKRSLRCRKCEHNLSKPE FNPTSIKFKIQLVAVNYIPEVRIMSIPNLRYMKESQVLLTLTNPVENLTHVTLFECEEGDPDDINSTAKVVVPPKELVLAGKDAAAEYDE -------------------------------------------------------------- >In-frame_ENST00000369332_ENST00000447998_TCGA-B6-A401_MAP3K7_chr6_91256976_-_DCTN4_chr5_150110302_length(transcript)=4740nt_BP=1372nt GGACACGGCTGTGGCCGCTGCCTCTACCCCCGCCACGGATCGCCGGGTAGTAGGACTGCGCGGCTCCAGGCTGAGGGTCGGTCCGGAGGC GGGTGGGCGCGGGTCTCACCCGGATTGTCCGGGTGGCACCGTTCCCGGCCCCACCGGGCGCCGCGAGGGATCATGTCTACAGCCTCTGCC GCCTCCTCCTCCTCCTCGTCTTCGGCCGGTGAGATGATCGAAGCCCCTTCCCAGGTCCTCAACTTTGAAGAGATCGACTACAAGGAGATC GAGGTGGAAGAGGTTGTTGGAAGAGGAGCCTTTGGAGTTGTTTGCAAAGCTAAGTGGAGAGCAAAAGATGTTGCTATTAAACAAATAGAA AGTGAATCTGAGAGGAAAGCGTTTATTGTAGAGCTTCGGCAGTTATCCCGTGTGAACCATCCTAATATTGTAAAGCTTTATGGAGCCTGC TTGAATCCAGTGTGTCTTGTGATGGAATATGCTGAAGGGGGCTCTTTATATAATGTGCTGCATGGTGCTGAACCATTGCCATATTATACT GCTGCCCACGCAATGAGTTGGTGTTTACAGTGTTCCCAAGGAGTGGCTTATCTTCACAGCATGCAACCCAAAGCGCTAATTCACAGGGAC CTGAAACCACCAAACTTACTGCTGGTTGCAGGGGGGACAGTTCTAAAAATTTGTGATTTTGGTACAGCCTGTGACATTCAGACACACATG ACCAATAACAAGGGGAGTGCTGCTTGGATGGCACCTGAAGTTTTTGAAGGTAGTAATTACAGTGAAAAATGTGACGTCTTCAGCTGGGGT ATTATTCTTTGGGAAGTGATAACGCGTCGGAAACCCTTTGATGAGATTGGTGGCCCAGCTTTCCGAATCATGTGGGCTGTTCATAATGGT ACTCGACCACCACTGATAAAAAATTTACCTAAGCCCATTGAGAGCCTGATGACTCGTTGTTGGTCTAAAGATCCTTCCCAGCGCCCTTCA ATGGAGGAAATTGTGAAAATAATGACTCACTTGATGCGGTACTTTCCAGGAGCAGATGAGCCATTACAGTATCCTTGTCAGTATTCAGAT GAAGGACAGAGCAACTCTGCCACCAGTACAGGCTCATTCATGGACATTGCTTCTACAAATACGAGTAACAAAAGTGACACTAATATGGAG CAAGTTCCTGCCACAAATGATACTATTAAGCGCTTAGAATCAAAATTGTTGAAAAATCAGGCAAAGCAACAGAGTGAATCTGGACGTTTA AGCTTGGGAGCCTCCCGTGGGAGCAGTGTGGAGAGCTTGCCCCCAACCTCTGAGGGCAAGAGGATGAGTGCTGACATGTCTGAAATAGAA GCTAGGATCGCCGCAACCACAGTAACAACCCTTCAGCAGCGTCTGTTACAGCCTGACTTCCAGCCAGTCTGTGCTTCACAGCTCTATCCT CGCCACAAACATCTTCTGATCAAACGGTCCCTGCGCTGCCGTAAATGTGAACATAATTTGAGCAAGCCAGAATTTAACCCAACGTCAATC AAATTCAAAATCCAGCTGGTCGCTGTCAATTATATTCCAGAAGTGAGAATCATGTCAATTCCCAACCTTCGCTACATGAAGGAGAGCCAG GTCCTCCTGACTCTTACAAATCCAGTTGAGAACCTCACCCATGTGACTCTCTTCGAGTGTGAGGAGGGGGACCCTGATGATATCAACAGC ACTGCTAAGGTGGTGGTGCCTCCCAAAGAGCTCGTTTTAGCTGGCAAGGATGCAGCAGCAGAGTACGATGAGTTGGCAGAACCTCAAGAC TTTCAGGACGATCCTGACATTATAGCCTTCAGAAAGGCCAACAAAGTGGGTATTTTCATCAAAGTTACACCACAGCGTGAGGAGGGTGAA GTGACCGTGTGCTTCAAGATGAAGCATGATTTTAAAAACCTGGCAGCCCCCATTCGCCCCATTGAAGAAAGTGACCAGGGAACAGAAGTC ATCTGGCTCACCCAGCATGTGGAACTTAGCTTGGGCCCACTTCTTCCTTAAAAGGTTCCACTGGAGGGCAGATCCCAAAGGACAGTATCA CCGTAAACCTGCGTTAAAATGTGGAAGCTGCTGCTTCATTAGGCCTTGTTTATAACGATGTACCCATGCACTACGGAATTCTATTGCTAA GAAAGTGGGAGCATAGGCAAGGCATTGGGAACACAGGGTAGCTGCTGTTGCTCTTGCTCTCACCCCTGTTGACACCAGTAAGTCTGTGTC TCCCTCACTGAACCCTGCACGTTGAGTAACAGCAGCATAATTCCATCCTAGGAAAGGGGATGGGTGTTCCTTGGAATGGCATTGTATTTA CCACCTGAGAAACTCTGTACTGTCTCTTGATCTGATCTCACTAAGGATCACAATGTCACAGATGAAACTTAAATGATAACCCAAAGGTAG ACCTGCTGTTAATGATCCAGCATTGGTCACAATGTACCAACTGCTTTCTGCATTCCGTTAAATATCATCTAACAGTCTAAAACATATCCC TTCATTGCCATAATGGCTGCCATTTTGCCATAGATTTCCATATAACTGAAAAACTGAATTGTCACTTTATCTTTAGTATCATGATGATTG GAAAAACCTGTGAAGTTGTTAAGGCACTCTCATTTGCCCTCTTTTTCTAAGTGAATACAGGACACGTATTAGTTGTTCTTAATTTTTTTC CCAGTAAAATATGGATCTTTTAAGAAGAATTTGAGAAGCAAACAATTACATGTCATGTCAAGGGGGTAGCAGATTCCATTCGTTTTCAAT ATTGCCACAATACCCAGGGATTAATGCTGCCACAGGGGGGCAATCTTTATTTGTCTTACTTCCTACCCCTTCCCTGTTCTGCCTCTTTAA CTCAGTTAAGTTGTTCTGTTTGGGACCTGGAAAAGAACCCAAAGAAAACCTGAGTGGACAGGTTCATTTCTGGAATGCAGAAAACATTTT AAAGGCTAGATTTTTAGAATATTCTCAACTAGCATTCTTTCCATTGATTTGAAGGGGAAATTAACTATTATAATCTCTTGAATCCAAAAC TGGATATTAAGAACTTTCCCCCTTACTAAGTTTAAGACTTTTGTCATGTGGTGAGTCAAATAAGACCATTTTGATTGTAAACCATAAAAT AGTTCAGCAAGTAGCCCACAGTTCTGGCCTAACAGCAGACTTGCTGTTTTCACTTGGTATCCTGGAGTTGGGTTGCTAACCTTAATTTCT ATGATGTTTTCTAAAATGAAACTTGATAAAGTAGACCACCAGCTGCACCGTGTTTTCTGTAAAAGTATTGTTAGTAAGTGGCCAAGAGAC TTGAGGAAAATACAGATTTTTTGTTTACCTTGGTCTTGTTTTAAGTCTTAAAAAATTAAAGATAACATTATAATGTAGAATACAGATGGG ACATAGTCCTTGTAAGCTTCCCTTGAAAATGTTTTAAATATTTAGGAAGCTTTTAAAAGACACTAAATTGTACTCTAAAAGACACTAAAT TGTACTAATTGTACAAAGGTCAAGCCAATTTTATGAAACAGTCCTACAGAGTAATATATGTGATGCAGTGTAAGAAGGAAAATACTCATC TCTAACATTATGGTAATAACATTTAGCCTCTTAGGAGTTGGAGCAGGGGGATGGGTAATTACAGATTTGCAGACTATAGAAAGAGTTTCA TTTTTTTGTGACCCCACAGAGTCTCAAATTTTTATTTCACTACCTGCTAGAGCCTACTGTGAAATCACTGCTCCATATTTGCCAGTGGAG GAAATGGGCATAGAGTAGAGAATAGCTTCATATGTTTACACGTTTGCATAGACTACACACATGTCATGCGTTTATGGCAGGTAGCTGGTA TTTATTCCCCAAAGTAATAATGTTGAAGTATGGGTCTCATCATTCCCATACACAGAAACACAAAACACTTTGATCATAAACTTTTTTCTT CAGAAGCCAAACTAACTTGCAGAATAATAGAGCCACTGGTTTAATGTTTCCTCAAGATAGGTTTTAGTGTAAGCTAGTATTCTGTGTGTT CGTAGAAATGATTCAATACCTGCAGCTGGTGAATTAGGAATTGTATTTGTTGCCTTTTTTATATTAGATGAGGTGCAAAAATTTTAATGC TAGTCAGTATGCACCACCACAGGAAAGTTAGATCCCATTAGCACTTGAAACTACAGCTTTGGAAACTTAGGCTAAGTTAATTTGGATTTG TTACTTGATTCACCTACTGACCTTTTCTTTTGTTTGAAGTGCTTATCAGCATAATGAGCTAAGTGTCATGCATATTTGTGAAGAAACACC CTTTTTGGTCCCTTTTGGGACAGAGAGGTACTCCTTGATCTTTATGAATGACAGGTTACTGTTTTGCCTTATTGCTTAACTTAATGTAGT GAAATAAAGCAGACAAAGCTTGAGCGTGTCTTTTGTTTGCTCTCATGTAGATACTAAGTAGCATGGCTCAGAGCCAAAAGACAAGCGTGA AGTTAAGAGAGTTGGCTAAGAGAGTTGGTGGGGCATGCTCCCTTCCATTCCTTAAATGAAGTAATCTAAAATCTCTTAGCAGGTTAGTTC ACCATAATATATAAGTAGATGTTGCTTTGAGCTTCTTATATACATATTCACAGAACCATTATATAAATGTTGTTAGACCTCTACCAGTTT >In-frame_ENST00000369332_ENST00000447998_TCGA-B6-A401_MAP3K7_chr6_91256976_-_DCTN4_chr5_150110302_length(amino acids)=638AA_start in transcript=114_stop in transcript=2030 MSGWHRSRPHRAPRGIMSTASAASSSSSSSAGEMIEAPSQVLNFEEIDYKEIEVEEVVGRGAFGVVCKAKWRAKDVAIKQIESESERKAF IVELRQLSRVNHPNIVKLYGACLNPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLL VAGGTVLKICDFGTACDIQTHMTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFRIMWAVHNGTRPPLIKN LPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHLMRYFPGADEPLQYPCQYSDEGQSNSATSTGSFMDIASTNTSNKSDTNMEQVPATNDT IKRLESKLLKNQAKQQSESGRLSLGASRGSSVESLPPTSEGKRMSADMSEIEARIAATTVTTLQQRLLQPDFQPVCASQLYPRHKHLLIK RSLRCRKCEHNLSKPEFNPTSIKFKIQLVAVNYIPEVRIMSIPNLRYMKESQVLLTLTNPVENLTHVTLFECEEGDPDDINSTAKVVVPP KELVLAGKDAAAEYDELAEPQDFQDDPDIIAFRKANKVGIFIKVTPQREEGEVTVCFKMKHDFKNLAAPIRPIEESDQGTEVIWLTQHVE -------------------------------------------------------------- >In-frame_ENST00000369332_ENST00000424236_TCGA-B6-A401_MAP3K7_chr6_91256976_-_DCTN4_chr5_150110302_length(transcript)=4432nt_BP=1372nt GGACACGGCTGTGGCCGCTGCCTCTACCCCCGCCACGGATCGCCGGGTAGTAGGACTGCGCGGCTCCAGGCTGAGGGTCGGTCCGGAGGC GGGTGGGCGCGGGTCTCACCCGGATTGTCCGGGTGGCACCGTTCCCGGCCCCACCGGGCGCCGCGAGGGATCATGTCTACAGCCTCTGCC GCCTCCTCCTCCTCCTCGTCTTCGGCCGGTGAGATGATCGAAGCCCCTTCCCAGGTCCTCAACTTTGAAGAGATCGACTACAAGGAGATC GAGGTGGAAGAGGTTGTTGGAAGAGGAGCCTTTGGAGTTGTTTGCAAAGCTAAGTGGAGAGCAAAAGATGTTGCTATTAAACAAATAGAA AGTGAATCTGAGAGGAAAGCGTTTATTGTAGAGCTTCGGCAGTTATCCCGTGTGAACCATCCTAATATTGTAAAGCTTTATGGAGCCTGC TTGAATCCAGTGTGTCTTGTGATGGAATATGCTGAAGGGGGCTCTTTATATAATGTGCTGCATGGTGCTGAACCATTGCCATATTATACT GCTGCCCACGCAATGAGTTGGTGTTTACAGTGTTCCCAAGGAGTGGCTTATCTTCACAGCATGCAACCCAAAGCGCTAATTCACAGGGAC CTGAAACCACCAAACTTACTGCTGGTTGCAGGGGGGACAGTTCTAAAAATTTGTGATTTTGGTACAGCCTGTGACATTCAGACACACATG ACCAATAACAAGGGGAGTGCTGCTTGGATGGCACCTGAAGTTTTTGAAGGTAGTAATTACAGTGAAAAATGTGACGTCTTCAGCTGGGGT ATTATTCTTTGGGAAGTGATAACGCGTCGGAAACCCTTTGATGAGATTGGTGGCCCAGCTTTCCGAATCATGTGGGCTGTTCATAATGGT ACTCGACCACCACTGATAAAAAATTTACCTAAGCCCATTGAGAGCCTGATGACTCGTTGTTGGTCTAAAGATCCTTCCCAGCGCCCTTCA ATGGAGGAAATTGTGAAAATAATGACTCACTTGATGCGGTACTTTCCAGGAGCAGATGAGCCATTACAGTATCCTTGTCAGTATTCAGAT GAAGGACAGAGCAACTCTGCCACCAGTACAGGCTCATTCATGGACATTGCTTCTACAAATACGAGTAACAAAAGTGACACTAATATGGAG CAAGTTCCTGCCACAAATGATACTATTAAGCGCTTAGAATCAAAATTGTTGAAAAATCAGGCAAAGCAACAGAGTGAATCTGGACGTTTA AGCTTGGGAGCCTCCCGTGGGAGCAGTGTGGAGAGCTTGCCCCCAACCTCTGAGGGCAAGAGGATGAGTGCTGACATGTCTGAAATAGAA GCTAGGATCGCCGCAACCACAGTAACAACCCTTCAGCAGCGTCTGTTACAGCCTGACTTCCAGCCAGTCTGTGCTTCACAGCTCTATCCT CGCCACAAACATCTTCTGATCAAACGGTCCCTGCGCTGCCGTAAATGTGAACATAATTTGAGCAAGCCAGAATTTAACCCAACGTCAATC AAATTCAAAATCCAGCTGGTCGCTGTCAATTATATTCCAGAAGTGAGAATCATGTCAATTCCCAACCTTCGCTACATGAAGGAGAGCCAG GTCCTCCTGACTCTTACAAATCCAGTTGAGAACCTCACCCATGTGACTCTCTTCGAGTGTGAGGAGGGGGACCCTGATGATATCAACAGC ACTGCTAAGGTGGTGGTGCCTCCCAAAGAGCTCGTTTTAGCTGGCAAGGATGCAGCAGCAGAGTACGATGAGTTGGCAGAACCTCAAGAC TTTCAGGACGATCCTGACATTATAGCCTTCAGAAAGGCCAACAAAGTGGGTATTTTCATCAAAGTTACACCACAGCGTGAGGAGGGTGAA GTGACCGTGTGCTTCAAGATGAAGCATGATTTTAAAAACCTGGCAGCCCCCATTCGCCCCATTGAAGAAAGTGACCAGGGAACAGAAGTC ATCTGGCTCACCCAGCATGTGGAACTTAGCTTGGGCCCACTTCTTCCTTAAAAGGTTCCACTGGAGGGCAGATCCCAAAGGACAGTATCA CCGTAAACCTGCGTTAAAATGTGGAAGCTGCTGCTTCATTAGGCCTTGTTTATAACGATGTACCCATGCACTACGGAATTCTATTGCTAA GAAAGTGGGAGCATAGGCAAGGCATTGGGAACACAGGGTAGCTGCTGTTGCTCTTGCTCTCACCCCTGTTGACACCAGTAAGTCTGTGTC TCCCTCACTGAACCCTGCACGTTGAGTAACAGCAGCATAATTCCATCCTAGGAAAGGGGATGGGTGTTCCTTGGAATGGCATTGTATTTA CCACCTGAGAAACTCTGTACTGTCTCTTGATCTGATCTCACTAAGGATCACAATGTCACAGATGAAACTTAAATGATAACCCAAAGGTAG ACCTGCTGTTAATGATCCAGCATTGGTCACAATGTACCAACTGCTTTCTGCATTCCGTTAAATATCATCTAACAGTCTAAAACATATCCC TTCATTGCCATAATGGCTGCCATTTTGCCATAGATTTCCATATAACTGAAAAACTGAATTGTCACTTTATCTTTAGTATCATGATGATTG GAAAAACCTGTGAAGTTGTTAAGGCACTCTCATTTGCCCTCTTTTTCTAAGTGAATACAGGACACGTATTAGTTGTTCTTAATTTTTTTC CCAGTAAAATATGGATCTTTTAAGAAGAATTTGAGAAGCAAACAATTACATGTCATGTCAAGGGGGTAGCAGATTCCATTCGTTTTCAAT ATTGCCACAATACCCAGGGATTAATGCTGCCACAGGGGGGCAATCTTTATTTGTCTTACTTCCTACCCCTTCCCTGTTCTGCCTCTTTAA CTCAGTTAAGTTGTTCTGTTTGGGACCTGGAAAAGAACCCAAAGAAAACCTGAGTGGACAGGTTCATTTCTGGAATGCAGAAAACATTTT AAAGGCTAGATTTTTAGAATATTCTCAACTAGCATTCTTTCCATTGATTTGAAGGGGAAATTAACTATTATAATCTCTTGAATCCAAAAC TGGATATTAAGAACTTTCCCCCTTACTAAGTTTAAGACTTTTGTCATGTGGTGAGTCAAATAAGACCATTTTGATTGTAAACCATAAAAT AGTTCAGCAAGTAGCCCACAGTTCTGGCCTAACAGCAGACTTGCTGTTTTCACTTGGTATCCTGGAGTTGGGTTGCTAACCTTAATTTCT ATGATGTTTTCTAAAATGAAACTTGATAAAGTAGACCACCAGCTGCACCGTGTTTTCTGTAAAAGTATTGTTAGTAAGTGGCCAAGAGAC TTGAGGAAAATACAGATTTTTTGTTTACCTTGGTCTTGTTTTAAGTCTTAAAAAATTAAAGATAACATTATAATGTAGAATACAGATGGG ACATAGTCCTTGTAAGCTTCCCTTGAAAATGTTTTAAATATTTAGGAAGCTTTTAAAAGACACTAAATTGTACTCTAAAAGACACTAAAT TGTACTAATTGTACAAAGGTCAAGCCAATTTTATGAAACAGTCCTACAGAGTAATATATGTGATGCAGTGTAAGAAGGAAAATACTCATC TCTAACATTATGGTAATAACATTTAGCCTCTTAGGAGTTGGAGCAGGGGGATGGGTAATTACAGATTTGCAGACTATAGAAAGAGTTTCA TTTTTTTGTGACCCCACAGAGTCTCAAATTTTTATTTCACTACCTGCTAGAGCCTACTGTGAAATCACTGCTCCATATTTGCCAGTGGAG GAAATGGGCATAGAGTAGAGAATAGCTTCATATGTTTACACGTTTGCATAGACTACACACATGTCATGCGTTTATGGCAGGTAGCTGGTA TTTATTCCCCAAAGTAATAATGTTGAAGTATGGGTCTCATCATTCCCATACACAGAAACACAAAACACTTTGATCATAAACTTTTTTCTT CAGAAGCCAAACTAACTTGCAGAATAATAGAGCCACTGGTTTAATGTTTCCTCAAGATAGGTTTTAGTGTAAGCTAGTATTCTGTGTGTT CGTAGAAATGATTCAATACCTGCAGCTGGTGAATTAGGAATTGTATTTGTTGCCTTTTTTATATTAGATGAGGTGCAAAAATTTTAATGC TAGTCAGTATGCACCACCACAGGAAAGTTAGATCCCATTAGCACTTGAAACTACAGCTTTGGAAACTTAGGCTAAGTTAATTTGGATTTG TTACTTGATTCACCTACTGACCTTTTCTTTTGTTTGAAGTGCTTATCAGCATAATGAGCTAAGTGTCATGCATATTTGTGAAGAAACACC CTTTTTGGTCCCTTTTGGGACAGAGAGGTACTCCTTGATCTTTATGAATGACAGGTTACTGTTTTGCCTTATTGCTTAACTTAATGTAGT >In-frame_ENST00000369332_ENST00000424236_TCGA-B6-A401_MAP3K7_chr6_91256976_-_DCTN4_chr5_150110302_length(amino acids)=638AA_start in transcript=114_stop in transcript=2030 MSGWHRSRPHRAPRGIMSTASAASSSSSSSAGEMIEAPSQVLNFEEIDYKEIEVEEVVGRGAFGVVCKAKWRAKDVAIKQIESESERKAF IVELRQLSRVNHPNIVKLYGACLNPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLL VAGGTVLKICDFGTACDIQTHMTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFRIMWAVHNGTRPPLIKN LPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHLMRYFPGADEPLQYPCQYSDEGQSNSATSTGSFMDIASTNTSNKSDTNMEQVPATNDT IKRLESKLLKNQAKQQSESGRLSLGASRGSSVESLPPTSEGKRMSADMSEIEARIAATTVTTLQQRLLQPDFQPVCASQLYPRHKHLLIK RSLRCRKCEHNLSKPEFNPTSIKFKIQLVAVNYIPEVRIMSIPNLRYMKESQVLLTLTNPVENLTHVTLFECEEGDPDDINSTAKVVVPP KELVLAGKDAAAEYDELAEPQDFQDDPDIIAFRKANKVGIFIKVTPQREEGEVTVCFKMKHDFKNLAAPIRPIEESDQGTEVIWLTQHVE -------------------------------------------------------------- >In-frame_ENST00000369332_ENST00000446090_TCGA-B6-A401_MAP3K7_chr6_91256976_-_DCTN4_chr5_150110302_length(transcript)=2322nt_BP=1372nt GGACACGGCTGTGGCCGCTGCCTCTACCCCCGCCACGGATCGCCGGGTAGTAGGACTGCGCGGCTCCAGGCTGAGGGTCGGTCCGGAGGC GGGTGGGCGCGGGTCTCACCCGGATTGTCCGGGTGGCACCGTTCCCGGCCCCACCGGGCGCCGCGAGGGATCATGTCTACAGCCTCTGCC GCCTCCTCCTCCTCCTCGTCTTCGGCCGGTGAGATGATCGAAGCCCCTTCCCAGGTCCTCAACTTTGAAGAGATCGACTACAAGGAGATC GAGGTGGAAGAGGTTGTTGGAAGAGGAGCCTTTGGAGTTGTTTGCAAAGCTAAGTGGAGAGCAAAAGATGTTGCTATTAAACAAATAGAA AGTGAATCTGAGAGGAAAGCGTTTATTGTAGAGCTTCGGCAGTTATCCCGTGTGAACCATCCTAATATTGTAAAGCTTTATGGAGCCTGC TTGAATCCAGTGTGTCTTGTGATGGAATATGCTGAAGGGGGCTCTTTATATAATGTGCTGCATGGTGCTGAACCATTGCCATATTATACT GCTGCCCACGCAATGAGTTGGTGTTTACAGTGTTCCCAAGGAGTGGCTTATCTTCACAGCATGCAACCCAAAGCGCTAATTCACAGGGAC CTGAAACCACCAAACTTACTGCTGGTTGCAGGGGGGACAGTTCTAAAAATTTGTGATTTTGGTACAGCCTGTGACATTCAGACACACATG ACCAATAACAAGGGGAGTGCTGCTTGGATGGCACCTGAAGTTTTTGAAGGTAGTAATTACAGTGAAAAATGTGACGTCTTCAGCTGGGGT ATTATTCTTTGGGAAGTGATAACGCGTCGGAAACCCTTTGATGAGATTGGTGGCCCAGCTTTCCGAATCATGTGGGCTGTTCATAATGGT ACTCGACCACCACTGATAAAAAATTTACCTAAGCCCATTGAGAGCCTGATGACTCGTTGTTGGTCTAAAGATCCTTCCCAGCGCCCTTCA ATGGAGGAAATTGTGAAAATAATGACTCACTTGATGCGGTACTTTCCAGGAGCAGATGAGCCATTACAGTATCCTTGTCAGTATTCAGAT GAAGGACAGAGCAACTCTGCCACCAGTACAGGCTCATTCATGGACATTGCTTCTACAAATACGAGTAACAAAAGTGACACTAATATGGAG CAAGTTCCTGCCACAAATGATACTATTAAGCGCTTAGAATCAAAATTGTTGAAAAATCAGGCAAAGCAACAGAGTGAATCTGGACGTTTA AGCTTGGGAGCCTCCCGTGGGAGCAGTGTGGAGAGCTTGCCCCCAACCTCTGAGGGCAAGAGGATGAGTGCTGACATGTCTGAAATAGAA GCTAGGATCGCCGCAACCACAGTAACAACCCTTCAGCAGCGTCTGTTACAGCCTGACTTCCAGCCAGTCTGTGCTTCACAGCTCTATCCT CGCCACAAACATCTTCTGATCAAACGGTCCCTGCGCTGCCGTAAATGTGAACATAATTTGAGCAAGCCAGAATTTAACCCAACGTCAATC AAATTCAAAATCCAGCTGGTCGCTGTCAATTATATTCCAGAAGTGAGAATCATGTCAATTCCCAACCTTCGCTACATGAAGGAGAGCCAG GTCCTCCTGACTCTTACAAATCCAGTTGAGAACCTCACCCATGTGACTCTCTTCGAGTGTGAGGAGGGGGACCCTGATGATATCAACAGC ACTGCTAAGGTGGTGGTGCCTCCCAAAGAGCTCGTTTTAGCTGGCAAGGATGCAGCAGCAGAGTACGATGAGTTGGCAGAACCTCAAGAC TTTCAGGACGATCCTGACATTATAGCCTTCAGAAAGGCCAACAAAGTGGGTATTTTCATCAAAGTTACACCACAGCGTGAGGAGGGTGAA GTGACCGTGTGCTTCAAGATGAAGCATGATTTTAAAAACCTGGCAGCCCCCATTCGCCCCATTGAAGAAAGTGACCAGGGAACAGAAGTC ATCTGGCTCACCCAGCATGTGGAACTTAGCTTGGGCCCACTTCTTCCTTAAAAGGTTCCACTGGAGGGCAGATCCCAAAGGACAGTATCA CCGTAAACCTGCGTTAAAATGTGGAAGCTGCTGCTTCATTAGGCCTTGTTTATAACGATGTACCCATGCACTACGGAATTCTATTGCTAA GAAAGTGGGAGCATAGGCAAGGCATTGGGAACACAGGGTAGCTGCTGTTGCTCTTGCTCTCACCCCTGTTGACACCAGTAAGTCTGTGTC >In-frame_ENST00000369332_ENST00000446090_TCGA-B6-A401_MAP3K7_chr6_91256976_-_DCTN4_chr5_150110302_length(amino acids)=638AA_start in transcript=114_stop in transcript=2030 MSGWHRSRPHRAPRGIMSTASAASSSSSSSAGEMIEAPSQVLNFEEIDYKEIEVEEVVGRGAFGVVCKAKWRAKDVAIKQIESESERKAF IVELRQLSRVNHPNIVKLYGACLNPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLL VAGGTVLKICDFGTACDIQTHMTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFRIMWAVHNGTRPPLIKN LPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHLMRYFPGADEPLQYPCQYSDEGQSNSATSTGSFMDIASTNTSNKSDTNMEQVPATNDT IKRLESKLLKNQAKQQSESGRLSLGASRGSSVESLPPTSEGKRMSADMSEIEARIAATTVTTLQQRLLQPDFQPVCASQLYPRHKHLLIK RSLRCRKCEHNLSKPEFNPTSIKFKIQLVAVNYIPEVRIMSIPNLRYMKESQVLLTLTNPVENLTHVTLFECEEGDPDDINSTAKVVVPP KELVLAGKDAAAEYDELAEPQDFQDDPDIIAFRKANKVGIFIKVTPQREEGEVTVCFKMKHDFKNLAAPIRPIEESDQGTEVIWLTQHVE -------------------------------------------------------------- >In-frame_ENST00000369329_ENST00000447998_TCGA-B6-A401_MAP3K7_chr6_91256976_-_DCTN4_chr5_150110302_length(transcript)=4740nt_BP=1372nt GGACACGGCTGTGGCCGCTGCCTCTACCCCCGCCACGGATCGCCGGGTAGTAGGACTGCGCGGCTCCAGGCTGAGGGTCGGTCCGGAGGC GGGTGGGCGCGGGTCTCACCCGGATTGTCCGGGTGGCACCGTTCCCGGCCCCACCGGGCGCCGCGAGGGATCATGTCTACAGCCTCTGCC GCCTCCTCCTCCTCCTCGTCTTCGGCCGGTGAGATGATCGAAGCCCCTTCCCAGGTCCTCAACTTTGAAGAGATCGACTACAAGGAGATC GAGGTGGAAGAGGTTGTTGGAAGAGGAGCCTTTGGAGTTGTTTGCAAAGCTAAGTGGAGAGCAAAAGATGTTGCTATTAAACAAATAGAA AGTGAATCTGAGAGGAAAGCGTTTATTGTAGAGCTTCGGCAGTTATCCCGTGTGAACCATCCTAATATTGTAAAGCTTTATGGAGCCTGC TTGAATCCAGTGTGTCTTGTGATGGAATATGCTGAAGGGGGCTCTTTATATAATGTGCTGCATGGTGCTGAACCATTGCCATATTATACT GCTGCCCACGCAATGAGTTGGTGTTTACAGTGTTCCCAAGGAGTGGCTTATCTTCACAGCATGCAACCCAAAGCGCTAATTCACAGGGAC CTGAAACCACCAAACTTACTGCTGGTTGCAGGGGGGACAGTTCTAAAAATTTGTGATTTTGGTACAGCCTGTGACATTCAGACACACATG ACCAATAACAAGGGGAGTGCTGCTTGGATGGCACCTGAAGTTTTTGAAGGTAGTAATTACAGTGAAAAATGTGACGTCTTCAGCTGGGGT ATTATTCTTTGGGAAGTGATAACGCGTCGGAAACCCTTTGATGAGATTGGTGGCCCAGCTTTCCGAATCATGTGGGCTGTTCATAATGGT ACTCGACCACCACTGATAAAAAATTTACCTAAGCCCATTGAGAGCCTGATGACTCGTTGTTGGTCTAAAGATCCTTCCCAGCGCCCTTCA ATGGAGGAAATTGTGAAAATAATGACTCACTTGATGCGGTACTTTCCAGGAGCAGATGAGCCATTACAGTATCCTTGTCAGTATTCAGAT GAAGGACAGAGCAACTCTGCCACCAGTACAGGCTCATTCATGGACATTGCTTCTACAAATACGAGTAACAAAAGTGACACTAATATGGAG CAAGTTCCTGCCACAAATGATACTATTAAGCGCTTAGAATCAAAATTGTTGAAAAATCAGGCAAAGCAACAGAGTGAATCTGGACGTTTA AGCTTGGGAGCCTCCCGTGGGAGCAGTGTGGAGAGCTTGCCCCCAACCTCTGAGGGCAAGAGGATGAGTGCTGACATGTCTGAAATAGAA GCTAGGATCGCCGCAACCACAGTAACAACCCTTCAGCAGCGTCTGTTACAGCCTGACTTCCAGCCAGTCTGTGCTTCACAGCTCTATCCT CGCCACAAACATCTTCTGATCAAACGGTCCCTGCGCTGCCGTAAATGTGAACATAATTTGAGCAAGCCAGAATTTAACCCAACGTCAATC AAATTCAAAATCCAGCTGGTCGCTGTCAATTATATTCCAGAAGTGAGAATCATGTCAATTCCCAACCTTCGCTACATGAAGGAGAGCCAG GTCCTCCTGACTCTTACAAATCCAGTTGAGAACCTCACCCATGTGACTCTCTTCGAGTGTGAGGAGGGGGACCCTGATGATATCAACAGC ACTGCTAAGGTGGTGGTGCCTCCCAAAGAGCTCGTTTTAGCTGGCAAGGATGCAGCAGCAGAGTACGATGAGTTGGCAGAACCTCAAGAC TTTCAGGACGATCCTGACATTATAGCCTTCAGAAAGGCCAACAAAGTGGGTATTTTCATCAAAGTTACACCACAGCGTGAGGAGGGTGAA GTGACCGTGTGCTTCAAGATGAAGCATGATTTTAAAAACCTGGCAGCCCCCATTCGCCCCATTGAAGAAAGTGACCAGGGAACAGAAGTC ATCTGGCTCACCCAGCATGTGGAACTTAGCTTGGGCCCACTTCTTCCTTAAAAGGTTCCACTGGAGGGCAGATCCCAAAGGACAGTATCA CCGTAAACCTGCGTTAAAATGTGGAAGCTGCTGCTTCATTAGGCCTTGTTTATAACGATGTACCCATGCACTACGGAATTCTATTGCTAA GAAAGTGGGAGCATAGGCAAGGCATTGGGAACACAGGGTAGCTGCTGTTGCTCTTGCTCTCACCCCTGTTGACACCAGTAAGTCTGTGTC TCCCTCACTGAACCCTGCACGTTGAGTAACAGCAGCATAATTCCATCCTAGGAAAGGGGATGGGTGTTCCTTGGAATGGCATTGTATTTA CCACCTGAGAAACTCTGTACTGTCTCTTGATCTGATCTCACTAAGGATCACAATGTCACAGATGAAACTTAAATGATAACCCAAAGGTAG ACCTGCTGTTAATGATCCAGCATTGGTCACAATGTACCAACTGCTTTCTGCATTCCGTTAAATATCATCTAACAGTCTAAAACATATCCC TTCATTGCCATAATGGCTGCCATTTTGCCATAGATTTCCATATAACTGAAAAACTGAATTGTCACTTTATCTTTAGTATCATGATGATTG GAAAAACCTGTGAAGTTGTTAAGGCACTCTCATTTGCCCTCTTTTTCTAAGTGAATACAGGACACGTATTAGTTGTTCTTAATTTTTTTC CCAGTAAAATATGGATCTTTTAAGAAGAATTTGAGAAGCAAACAATTACATGTCATGTCAAGGGGGTAGCAGATTCCATTCGTTTTCAAT ATTGCCACAATACCCAGGGATTAATGCTGCCACAGGGGGGCAATCTTTATTTGTCTTACTTCCTACCCCTTCCCTGTTCTGCCTCTTTAA CTCAGTTAAGTTGTTCTGTTTGGGACCTGGAAAAGAACCCAAAGAAAACCTGAGTGGACAGGTTCATTTCTGGAATGCAGAAAACATTTT AAAGGCTAGATTTTTAGAATATTCTCAACTAGCATTCTTTCCATTGATTTGAAGGGGAAATTAACTATTATAATCTCTTGAATCCAAAAC TGGATATTAAGAACTTTCCCCCTTACTAAGTTTAAGACTTTTGTCATGTGGTGAGTCAAATAAGACCATTTTGATTGTAAACCATAAAAT AGTTCAGCAAGTAGCCCACAGTTCTGGCCTAACAGCAGACTTGCTGTTTTCACTTGGTATCCTGGAGTTGGGTTGCTAACCTTAATTTCT ATGATGTTTTCTAAAATGAAACTTGATAAAGTAGACCACCAGCTGCACCGTGTTTTCTGTAAAAGTATTGTTAGTAAGTGGCCAAGAGAC TTGAGGAAAATACAGATTTTTTGTTTACCTTGGTCTTGTTTTAAGTCTTAAAAAATTAAAGATAACATTATAATGTAGAATACAGATGGG ACATAGTCCTTGTAAGCTTCCCTTGAAAATGTTTTAAATATTTAGGAAGCTTTTAAAAGACACTAAATTGTACTCTAAAAGACACTAAAT TGTACTAATTGTACAAAGGTCAAGCCAATTTTATGAAACAGTCCTACAGAGTAATATATGTGATGCAGTGTAAGAAGGAAAATACTCATC TCTAACATTATGGTAATAACATTTAGCCTCTTAGGAGTTGGAGCAGGGGGATGGGTAATTACAGATTTGCAGACTATAGAAAGAGTTTCA TTTTTTTGTGACCCCACAGAGTCTCAAATTTTTATTTCACTACCTGCTAGAGCCTACTGTGAAATCACTGCTCCATATTTGCCAGTGGAG GAAATGGGCATAGAGTAGAGAATAGCTTCATATGTTTACACGTTTGCATAGACTACACACATGTCATGCGTTTATGGCAGGTAGCTGGTA TTTATTCCCCAAAGTAATAATGTTGAAGTATGGGTCTCATCATTCCCATACACAGAAACACAAAACACTTTGATCATAAACTTTTTTCTT CAGAAGCCAAACTAACTTGCAGAATAATAGAGCCACTGGTTTAATGTTTCCTCAAGATAGGTTTTAGTGTAAGCTAGTATTCTGTGTGTT CGTAGAAATGATTCAATACCTGCAGCTGGTGAATTAGGAATTGTATTTGTTGCCTTTTTTATATTAGATGAGGTGCAAAAATTTTAATGC TAGTCAGTATGCACCACCACAGGAAAGTTAGATCCCATTAGCACTTGAAACTACAGCTTTGGAAACTTAGGCTAAGTTAATTTGGATTTG TTACTTGATTCACCTACTGACCTTTTCTTTTGTTTGAAGTGCTTATCAGCATAATGAGCTAAGTGTCATGCATATTTGTGAAGAAACACC CTTTTTGGTCCCTTTTGGGACAGAGAGGTACTCCTTGATCTTTATGAATGACAGGTTACTGTTTTGCCTTATTGCTTAACTTAATGTAGT GAAATAAAGCAGACAAAGCTTGAGCGTGTCTTTTGTTTGCTCTCATGTAGATACTAAGTAGCATGGCTCAGAGCCAAAAGACAAGCGTGA AGTTAAGAGAGTTGGCTAAGAGAGTTGGTGGGGCATGCTCCCTTCCATTCCTTAAATGAAGTAATCTAAAATCTCTTAGCAGGTTAGTTC ACCATAATATATAAGTAGATGTTGCTTTGAGCTTCTTATATACATATTCACAGAACCATTATATAAATGTTGTTAGACCTCTACCAGTTT >In-frame_ENST00000369329_ENST00000447998_TCGA-B6-A401_MAP3K7_chr6_91256976_-_DCTN4_chr5_150110302_length(amino acids)=638AA_start in transcript=114_stop in transcript=2030 MSGWHRSRPHRAPRGIMSTASAASSSSSSSAGEMIEAPSQVLNFEEIDYKEIEVEEVVGRGAFGVVCKAKWRAKDVAIKQIESESERKAF IVELRQLSRVNHPNIVKLYGACLNPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLL VAGGTVLKICDFGTACDIQTHMTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFRIMWAVHNGTRPPLIKN LPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHLMRYFPGADEPLQYPCQYSDEGQSNSATSTGSFMDIASTNTSNKSDTNMEQVPATNDT IKRLESKLLKNQAKQQSESGRLSLGASRGSSVESLPPTSEGKRMSADMSEIEARIAATTVTTLQQRLLQPDFQPVCASQLYPRHKHLLIK RSLRCRKCEHNLSKPEFNPTSIKFKIQLVAVNYIPEVRIMSIPNLRYMKESQVLLTLTNPVENLTHVTLFECEEGDPDDINSTAKVVVPP KELVLAGKDAAAEYDELAEPQDFQDDPDIIAFRKANKVGIFIKVTPQREEGEVTVCFKMKHDFKNLAAPIRPIEESDQGTEVIWLTQHVE -------------------------------------------------------------- >In-frame_ENST00000369329_ENST00000424236_TCGA-B6-A401_MAP3K7_chr6_91256976_-_DCTN4_chr5_150110302_length(transcript)=4432nt_BP=1372nt GGACACGGCTGTGGCCGCTGCCTCTACCCCCGCCACGGATCGCCGGGTAGTAGGACTGCGCGGCTCCAGGCTGAGGGTCGGTCCGGAGGC GGGTGGGCGCGGGTCTCACCCGGATTGTCCGGGTGGCACCGTTCCCGGCCCCACCGGGCGCCGCGAGGGATCATGTCTACAGCCTCTGCC GCCTCCTCCTCCTCCTCGTCTTCGGCCGGTGAGATGATCGAAGCCCCTTCCCAGGTCCTCAACTTTGAAGAGATCGACTACAAGGAGATC GAGGTGGAAGAGGTTGTTGGAAGAGGAGCCTTTGGAGTTGTTTGCAAAGCTAAGTGGAGAGCAAAAGATGTTGCTATTAAACAAATAGAA AGTGAATCTGAGAGGAAAGCGTTTATTGTAGAGCTTCGGCAGTTATCCCGTGTGAACCATCCTAATATTGTAAAGCTTTATGGAGCCTGC TTGAATCCAGTGTGTCTTGTGATGGAATATGCTGAAGGGGGCTCTTTATATAATGTGCTGCATGGTGCTGAACCATTGCCATATTATACT GCTGCCCACGCAATGAGTTGGTGTTTACAGTGTTCCCAAGGAGTGGCTTATCTTCACAGCATGCAACCCAAAGCGCTAATTCACAGGGAC CTGAAACCACCAAACTTACTGCTGGTTGCAGGGGGGACAGTTCTAAAAATTTGTGATTTTGGTACAGCCTGTGACATTCAGACACACATG ACCAATAACAAGGGGAGTGCTGCTTGGATGGCACCTGAAGTTTTTGAAGGTAGTAATTACAGTGAAAAATGTGACGTCTTCAGCTGGGGT ATTATTCTTTGGGAAGTGATAACGCGTCGGAAACCCTTTGATGAGATTGGTGGCCCAGCTTTCCGAATCATGTGGGCTGTTCATAATGGT ACTCGACCACCACTGATAAAAAATTTACCTAAGCCCATTGAGAGCCTGATGACTCGTTGTTGGTCTAAAGATCCTTCCCAGCGCCCTTCA ATGGAGGAAATTGTGAAAATAATGACTCACTTGATGCGGTACTTTCCAGGAGCAGATGAGCCATTACAGTATCCTTGTCAGTATTCAGAT GAAGGACAGAGCAACTCTGCCACCAGTACAGGCTCATTCATGGACATTGCTTCTACAAATACGAGTAACAAAAGTGACACTAATATGGAG CAAGTTCCTGCCACAAATGATACTATTAAGCGCTTAGAATCAAAATTGTTGAAAAATCAGGCAAAGCAACAGAGTGAATCTGGACGTTTA AGCTTGGGAGCCTCCCGTGGGAGCAGTGTGGAGAGCTTGCCCCCAACCTCTGAGGGCAAGAGGATGAGTGCTGACATGTCTGAAATAGAA GCTAGGATCGCCGCAACCACAGTAACAACCCTTCAGCAGCGTCTGTTACAGCCTGACTTCCAGCCAGTCTGTGCTTCACAGCTCTATCCT CGCCACAAACATCTTCTGATCAAACGGTCCCTGCGCTGCCGTAAATGTGAACATAATTTGAGCAAGCCAGAATTTAACCCAACGTCAATC AAATTCAAAATCCAGCTGGTCGCTGTCAATTATATTCCAGAAGTGAGAATCATGTCAATTCCCAACCTTCGCTACATGAAGGAGAGCCAG GTCCTCCTGACTCTTACAAATCCAGTTGAGAACCTCACCCATGTGACTCTCTTCGAGTGTGAGGAGGGGGACCCTGATGATATCAACAGC ACTGCTAAGGTGGTGGTGCCTCCCAAAGAGCTCGTTTTAGCTGGCAAGGATGCAGCAGCAGAGTACGATGAGTTGGCAGAACCTCAAGAC TTTCAGGACGATCCTGACATTATAGCCTTCAGAAAGGCCAACAAAGTGGGTATTTTCATCAAAGTTACACCACAGCGTGAGGAGGGTGAA GTGACCGTGTGCTTCAAGATGAAGCATGATTTTAAAAACCTGGCAGCCCCCATTCGCCCCATTGAAGAAAGTGACCAGGGAACAGAAGTC ATCTGGCTCACCCAGCATGTGGAACTTAGCTTGGGCCCACTTCTTCCTTAAAAGGTTCCACTGGAGGGCAGATCCCAAAGGACAGTATCA CCGTAAACCTGCGTTAAAATGTGGAAGCTGCTGCTTCATTAGGCCTTGTTTATAACGATGTACCCATGCACTACGGAATTCTATTGCTAA GAAAGTGGGAGCATAGGCAAGGCATTGGGAACACAGGGTAGCTGCTGTTGCTCTTGCTCTCACCCCTGTTGACACCAGTAAGTCTGTGTC TCCCTCACTGAACCCTGCACGTTGAGTAACAGCAGCATAATTCCATCCTAGGAAAGGGGATGGGTGTTCCTTGGAATGGCATTGTATTTA CCACCTGAGAAACTCTGTACTGTCTCTTGATCTGATCTCACTAAGGATCACAATGTCACAGATGAAACTTAAATGATAACCCAAAGGTAG ACCTGCTGTTAATGATCCAGCATTGGTCACAATGTACCAACTGCTTTCTGCATTCCGTTAAATATCATCTAACAGTCTAAAACATATCCC TTCATTGCCATAATGGCTGCCATTTTGCCATAGATTTCCATATAACTGAAAAACTGAATTGTCACTTTATCTTTAGTATCATGATGATTG GAAAAACCTGTGAAGTTGTTAAGGCACTCTCATTTGCCCTCTTTTTCTAAGTGAATACAGGACACGTATTAGTTGTTCTTAATTTTTTTC CCAGTAAAATATGGATCTTTTAAGAAGAATTTGAGAAGCAAACAATTACATGTCATGTCAAGGGGGTAGCAGATTCCATTCGTTTTCAAT ATTGCCACAATACCCAGGGATTAATGCTGCCACAGGGGGGCAATCTTTATTTGTCTTACTTCCTACCCCTTCCCTGTTCTGCCTCTTTAA CTCAGTTAAGTTGTTCTGTTTGGGACCTGGAAAAGAACCCAAAGAAAACCTGAGTGGACAGGTTCATTTCTGGAATGCAGAAAACATTTT AAAGGCTAGATTTTTAGAATATTCTCAACTAGCATTCTTTCCATTGATTTGAAGGGGAAATTAACTATTATAATCTCTTGAATCCAAAAC TGGATATTAAGAACTTTCCCCCTTACTAAGTTTAAGACTTTTGTCATGTGGTGAGTCAAATAAGACCATTTTGATTGTAAACCATAAAAT AGTTCAGCAAGTAGCCCACAGTTCTGGCCTAACAGCAGACTTGCTGTTTTCACTTGGTATCCTGGAGTTGGGTTGCTAACCTTAATTTCT ATGATGTTTTCTAAAATGAAACTTGATAAAGTAGACCACCAGCTGCACCGTGTTTTCTGTAAAAGTATTGTTAGTAAGTGGCCAAGAGAC TTGAGGAAAATACAGATTTTTTGTTTACCTTGGTCTTGTTTTAAGTCTTAAAAAATTAAAGATAACATTATAATGTAGAATACAGATGGG ACATAGTCCTTGTAAGCTTCCCTTGAAAATGTTTTAAATATTTAGGAAGCTTTTAAAAGACACTAAATTGTACTCTAAAAGACACTAAAT TGTACTAATTGTACAAAGGTCAAGCCAATTTTATGAAACAGTCCTACAGAGTAATATATGTGATGCAGTGTAAGAAGGAAAATACTCATC TCTAACATTATGGTAATAACATTTAGCCTCTTAGGAGTTGGAGCAGGGGGATGGGTAATTACAGATTTGCAGACTATAGAAAGAGTTTCA TTTTTTTGTGACCCCACAGAGTCTCAAATTTTTATTTCACTACCTGCTAGAGCCTACTGTGAAATCACTGCTCCATATTTGCCAGTGGAG GAAATGGGCATAGAGTAGAGAATAGCTTCATATGTTTACACGTTTGCATAGACTACACACATGTCATGCGTTTATGGCAGGTAGCTGGTA TTTATTCCCCAAAGTAATAATGTTGAAGTATGGGTCTCATCATTCCCATACACAGAAACACAAAACACTTTGATCATAAACTTTTTTCTT CAGAAGCCAAACTAACTTGCAGAATAATAGAGCCACTGGTTTAATGTTTCCTCAAGATAGGTTTTAGTGTAAGCTAGTATTCTGTGTGTT CGTAGAAATGATTCAATACCTGCAGCTGGTGAATTAGGAATTGTATTTGTTGCCTTTTTTATATTAGATGAGGTGCAAAAATTTTAATGC TAGTCAGTATGCACCACCACAGGAAAGTTAGATCCCATTAGCACTTGAAACTACAGCTTTGGAAACTTAGGCTAAGTTAATTTGGATTTG TTACTTGATTCACCTACTGACCTTTTCTTTTGTTTGAAGTGCTTATCAGCATAATGAGCTAAGTGTCATGCATATTTGTGAAGAAACACC CTTTTTGGTCCCTTTTGGGACAGAGAGGTACTCCTTGATCTTTATGAATGACAGGTTACTGTTTTGCCTTATTGCTTAACTTAATGTAGT >In-frame_ENST00000369329_ENST00000424236_TCGA-B6-A401_MAP3K7_chr6_91256976_-_DCTN4_chr5_150110302_length(amino acids)=638AA_start in transcript=114_stop in transcript=2030 MSGWHRSRPHRAPRGIMSTASAASSSSSSSAGEMIEAPSQVLNFEEIDYKEIEVEEVVGRGAFGVVCKAKWRAKDVAIKQIESESERKAF IVELRQLSRVNHPNIVKLYGACLNPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLL VAGGTVLKICDFGTACDIQTHMTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFRIMWAVHNGTRPPLIKN LPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHLMRYFPGADEPLQYPCQYSDEGQSNSATSTGSFMDIASTNTSNKSDTNMEQVPATNDT IKRLESKLLKNQAKQQSESGRLSLGASRGSSVESLPPTSEGKRMSADMSEIEARIAATTVTTLQQRLLQPDFQPVCASQLYPRHKHLLIK RSLRCRKCEHNLSKPEFNPTSIKFKIQLVAVNYIPEVRIMSIPNLRYMKESQVLLTLTNPVENLTHVTLFECEEGDPDDINSTAKVVVPP KELVLAGKDAAAEYDELAEPQDFQDDPDIIAFRKANKVGIFIKVTPQREEGEVTVCFKMKHDFKNLAAPIRPIEESDQGTEVIWLTQHVE -------------------------------------------------------------- >In-frame_ENST00000369329_ENST00000446090_TCGA-B6-A401_MAP3K7_chr6_91256976_-_DCTN4_chr5_150110302_length(transcript)=2322nt_BP=1372nt GGACACGGCTGTGGCCGCTGCCTCTACCCCCGCCACGGATCGCCGGGTAGTAGGACTGCGCGGCTCCAGGCTGAGGGTCGGTCCGGAGGC GGGTGGGCGCGGGTCTCACCCGGATTGTCCGGGTGGCACCGTTCCCGGCCCCACCGGGCGCCGCGAGGGATCATGTCTACAGCCTCTGCC GCCTCCTCCTCCTCCTCGTCTTCGGCCGGTGAGATGATCGAAGCCCCTTCCCAGGTCCTCAACTTTGAAGAGATCGACTACAAGGAGATC GAGGTGGAAGAGGTTGTTGGAAGAGGAGCCTTTGGAGTTGTTTGCAAAGCTAAGTGGAGAGCAAAAGATGTTGCTATTAAACAAATAGAA AGTGAATCTGAGAGGAAAGCGTTTATTGTAGAGCTTCGGCAGTTATCCCGTGTGAACCATCCTAATATTGTAAAGCTTTATGGAGCCTGC TTGAATCCAGTGTGTCTTGTGATGGAATATGCTGAAGGGGGCTCTTTATATAATGTGCTGCATGGTGCTGAACCATTGCCATATTATACT GCTGCCCACGCAATGAGTTGGTGTTTACAGTGTTCCCAAGGAGTGGCTTATCTTCACAGCATGCAACCCAAAGCGCTAATTCACAGGGAC CTGAAACCACCAAACTTACTGCTGGTTGCAGGGGGGACAGTTCTAAAAATTTGTGATTTTGGTACAGCCTGTGACATTCAGACACACATG ACCAATAACAAGGGGAGTGCTGCTTGGATGGCACCTGAAGTTTTTGAAGGTAGTAATTACAGTGAAAAATGTGACGTCTTCAGCTGGGGT ATTATTCTTTGGGAAGTGATAACGCGTCGGAAACCCTTTGATGAGATTGGTGGCCCAGCTTTCCGAATCATGTGGGCTGTTCATAATGGT ACTCGACCACCACTGATAAAAAATTTACCTAAGCCCATTGAGAGCCTGATGACTCGTTGTTGGTCTAAAGATCCTTCCCAGCGCCCTTCA ATGGAGGAAATTGTGAAAATAATGACTCACTTGATGCGGTACTTTCCAGGAGCAGATGAGCCATTACAGTATCCTTGTCAGTATTCAGAT GAAGGACAGAGCAACTCTGCCACCAGTACAGGCTCATTCATGGACATTGCTTCTACAAATACGAGTAACAAAAGTGACACTAATATGGAG CAAGTTCCTGCCACAAATGATACTATTAAGCGCTTAGAATCAAAATTGTTGAAAAATCAGGCAAAGCAACAGAGTGAATCTGGACGTTTA AGCTTGGGAGCCTCCCGTGGGAGCAGTGTGGAGAGCTTGCCCCCAACCTCTGAGGGCAAGAGGATGAGTGCTGACATGTCTGAAATAGAA GCTAGGATCGCCGCAACCACAGTAACAACCCTTCAGCAGCGTCTGTTACAGCCTGACTTCCAGCCAGTCTGTGCTTCACAGCTCTATCCT CGCCACAAACATCTTCTGATCAAACGGTCCCTGCGCTGCCGTAAATGTGAACATAATTTGAGCAAGCCAGAATTTAACCCAACGTCAATC AAATTCAAAATCCAGCTGGTCGCTGTCAATTATATTCCAGAAGTGAGAATCATGTCAATTCCCAACCTTCGCTACATGAAGGAGAGCCAG GTCCTCCTGACTCTTACAAATCCAGTTGAGAACCTCACCCATGTGACTCTCTTCGAGTGTGAGGAGGGGGACCCTGATGATATCAACAGC ACTGCTAAGGTGGTGGTGCCTCCCAAAGAGCTCGTTTTAGCTGGCAAGGATGCAGCAGCAGAGTACGATGAGTTGGCAGAACCTCAAGAC TTTCAGGACGATCCTGACATTATAGCCTTCAGAAAGGCCAACAAAGTGGGTATTTTCATCAAAGTTACACCACAGCGTGAGGAGGGTGAA GTGACCGTGTGCTTCAAGATGAAGCATGATTTTAAAAACCTGGCAGCCCCCATTCGCCCCATTGAAGAAAGTGACCAGGGAACAGAAGTC ATCTGGCTCACCCAGCATGTGGAACTTAGCTTGGGCCCACTTCTTCCTTAAAAGGTTCCACTGGAGGGCAGATCCCAAAGGACAGTATCA CCGTAAACCTGCGTTAAAATGTGGAAGCTGCTGCTTCATTAGGCCTTGTTTATAACGATGTACCCATGCACTACGGAATTCTATTGCTAA GAAAGTGGGAGCATAGGCAAGGCATTGGGAACACAGGGTAGCTGCTGTTGCTCTTGCTCTCACCCCTGTTGACACCAGTAAGTCTGTGTC >In-frame_ENST00000369329_ENST00000446090_TCGA-B6-A401_MAP3K7_chr6_91256976_-_DCTN4_chr5_150110302_length(amino acids)=638AA_start in transcript=114_stop in transcript=2030 MSGWHRSRPHRAPRGIMSTASAASSSSSSSAGEMIEAPSQVLNFEEIDYKEIEVEEVVGRGAFGVVCKAKWRAKDVAIKQIESESERKAF IVELRQLSRVNHPNIVKLYGACLNPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLL VAGGTVLKICDFGTACDIQTHMTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFRIMWAVHNGTRPPLIKN LPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHLMRYFPGADEPLQYPCQYSDEGQSNSATSTGSFMDIASTNTSNKSDTNMEQVPATNDT IKRLESKLLKNQAKQQSESGRLSLGASRGSSVESLPPTSEGKRMSADMSEIEARIAATTVTTLQQRLLQPDFQPVCASQLYPRHKHLLIK RSLRCRKCEHNLSKPEFNPTSIKFKIQLVAVNYIPEVRIMSIPNLRYMKESQVLLTLTNPVENLTHVTLFECEEGDPDDINSTAKVVVPP KELVLAGKDAAAEYDELAEPQDFQDDPDIIAFRKANKVGIFIKVTPQREEGEVTVCFKMKHDFKNLAAPIRPIEESDQGTEVIWLTQHVE -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for MAP3K7-DCTN4 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| Hgene | MAP3K7 | chr6:91256976 | chr5:150110302 | ENST00000369325 | - | 11 | 16 | 1_300 | 403.3333333333333 | 519.0 | MAPK8IP1 |
| Hgene | MAP3K7 | chr6:91256976 | chr5:150110302 | ENST00000369327 | - | 11 | 15 | 1_300 | 403.3333333333333 | 492.0 | MAPK8IP1 |
| Hgene | MAP3K7 | chr6:91256976 | chr5:150110302 | ENST00000369329 | - | 11 | 17 | 1_300 | 403.3333333333333 | 607.0 | MAPK8IP1 |
| Hgene | MAP3K7 | chr6:91256976 | chr5:150110302 | ENST00000369332 | - | 11 | 16 | 1_300 | 403.3333333333333 | 580.0 | MAPK8IP1 |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for MAP3K7-DCTN4 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for MAP3K7-DCTN4 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | MAP3K7 | C4310697 | FRONTOMETAPHYSEAL DYSPLASIA 2 | 3 | GENOMICS_ENGLAND;UNIPROT |
| Hgene | MAP3K7 | C2931461 | Forney Robinson Pascoe syndrome | 2 | CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT |
| Hgene | MAP3K7 | C0005398 | Cholestasis, Extrahepatic | 1 | CTD_human |
| Hgene | MAP3K7 | C0033578 | Prostatic Neoplasms | 1 | CTD_human |
| Hgene | MAP3K7 | C0265293 | Frontometaphyseal dysplasia | 1 | CTD_human;GENOMICS_ENGLAND;ORPHANET |
| Hgene | MAP3K7 | C0376358 | Malignant neoplasm of prostate | 1 | CTD_human |
| Hgene | MAP3K7 | C4281559 | FRONTOMETAPHYSEAL DYSPLASIA 1 | 1 | GENOMICS_ENGLAND |
| Tgene | DCTN4 | C0010674 | Cystic Fibrosis | 1 | CTD_human;ORPHANET |
| Tgene | DCTN4 | C0033817 | Pseudomonas Infections | 1 | CTD_human |
| Tgene | DCTN4 | C0392164 | Pulmonary Cystic Fibrosis | 1 | CTD_human |
| Tgene | DCTN4 | C0854135 | Pseudomonas aeruginosa infection | 1 | CTD_human |
| Tgene | DCTN4 | C1527396 | Fibrocystic Disease of Pancreas | 1 | CTD_human |
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