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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:MGLL-EEFSEC (FusionGDB2 ID:53078)

Fusion Gene Summary for MGLL-EEFSEC

check button Fusion gene summary
Fusion gene informationFusion gene name: MGLL-EEFSEC
Fusion gene ID: 53078
HgeneTgene
Gene symbol

MGLL

EEFSEC

Gene ID

11343

60678

Gene namemonoglyceride lipaseeukaryotic elongation factor, selenocysteine-tRNA specific
SynonymsHU-K5|HUK5|MAGL|MGLEFSEC|SELB
Cytomap

3q21.3

3q21.3

Type of geneprotein-codingprotein-coding
Descriptionmonoglyceride lipaselysophospholipase homologmonoacylglycerol lipaseselenocysteine-specific elongation factorelongation factor for selenoprotein translationelongation factor secselenocysteine (Sec)-specific eukaryotic elongation factor
Modification date2020031320200313
UniProtAcc.

P57772

Ensembl transtripts involved in fusion geneENST00000434178, ENST00000265052, 
ENST00000398104, ENST00000453507, 
ENST00000476682, ENST00000398101, 
ENST00000254730, ENST00000483457, 
ENST00000483569, 
Fusion gene scores* DoF score7 X 7 X 4=1967 X 5 X 8=280
# samples 89
** MAII scorelog2(8/196*10)=-1.29278174922785
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(9/280*10)=-1.63742992061529
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: MGLL [Title/Abstract] AND EEFSEC [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointMGLL(127500631)-EEFSEC(127965678), # samples:2
Anticipated loss of major functional domain due to fusion event.MGLL-EEFSEC seems lost the major protein functional domain in Hgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
MGLL-EEFSEC seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
MGLL-EEFSEC seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneMGLL

GO:0046464

acylglycerol catabolic process

22969151


check buttonFusion gene breakpoints across MGLL (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across EEFSEC (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4ESCATCGA-VR-A8Q7MGLLchr3

127500631

-EEFSECchr3

127965678

+
ChimerDB4ESCATCGA-VR-A8Q7MGLLchr3

127500631

-EEFSECchr3

127965678

+
ChimerDB4STADTCGA-BR-8058-01AMGLLchr3

127500632

-EEFSECchr3

127965679

+


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Fusion Gene ORF analysis for MGLL-EEFSEC

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000434178ENST00000254730MGLLchr3

127500631

-EEFSECchr3

127965678

+
Frame-shiftENST00000434178ENST00000483457MGLLchr3

127500631

-EEFSECchr3

127965678

+
5CDS-intronENST00000434178ENST00000483569MGLLchr3

127500631

-EEFSECchr3

127965678

+
In-frameENST00000265052ENST00000254730MGLLchr3

127500631

-EEFSECchr3

127965678

+
In-frameENST00000265052ENST00000483457MGLLchr3

127500631

-EEFSECchr3

127965678

+
5CDS-intronENST00000265052ENST00000483569MGLLchr3

127500631

-EEFSECchr3

127965678

+
In-frameENST00000398104ENST00000254730MGLLchr3

127500631

-EEFSECchr3

127965678

+
In-frameENST00000398104ENST00000483457MGLLchr3

127500631

-EEFSECchr3

127965678

+
5CDS-intronENST00000398104ENST00000483569MGLLchr3

127500631

-EEFSECchr3

127965678

+
In-frameENST00000453507ENST00000254730MGLLchr3

127500631

-EEFSECchr3

127965678

+
In-frameENST00000453507ENST00000483457MGLLchr3

127500631

-EEFSECchr3

127965678

+
5CDS-intronENST00000453507ENST00000483569MGLLchr3

127500631

-EEFSECchr3

127965678

+
intron-3CDSENST00000476682ENST00000254730MGLLchr3

127500631

-EEFSECchr3

127965678

+
intron-3CDSENST00000476682ENST00000483457MGLLchr3

127500631

-EEFSECchr3

127965678

+
intron-intronENST00000476682ENST00000483569MGLLchr3

127500631

-EEFSECchr3

127965678

+
intron-3CDSENST00000398101ENST00000254730MGLLchr3

127500631

-EEFSECchr3

127965678

+
intron-3CDSENST00000398101ENST00000483457MGLLchr3

127500631

-EEFSECchr3

127965678

+
intron-intronENST00000398101ENST00000483569MGLLchr3

127500631

-EEFSECchr3

127965678

+
Frame-shiftENST00000434178ENST00000254730MGLLchr3

127500632

-EEFSECchr3

127965679

+
Frame-shiftENST00000434178ENST00000483457MGLLchr3

127500632

-EEFSECchr3

127965679

+
5CDS-intronENST00000434178ENST00000483569MGLLchr3

127500632

-EEFSECchr3

127965679

+
In-frameENST00000265052ENST00000254730MGLLchr3

127500632

-EEFSECchr3

127965679

+
In-frameENST00000265052ENST00000483457MGLLchr3

127500632

-EEFSECchr3

127965679

+
5CDS-intronENST00000265052ENST00000483569MGLLchr3

127500632

-EEFSECchr3

127965679

+
In-frameENST00000398104ENST00000254730MGLLchr3

127500632

-EEFSECchr3

127965679

+
In-frameENST00000398104ENST00000483457MGLLchr3

127500632

-EEFSECchr3

127965679

+
5CDS-intronENST00000398104ENST00000483569MGLLchr3

127500632

-EEFSECchr3

127965679

+
In-frameENST00000453507ENST00000254730MGLLchr3

127500632

-EEFSECchr3

127965679

+
In-frameENST00000453507ENST00000483457MGLLchr3

127500632

-EEFSECchr3

127965679

+
5CDS-intronENST00000453507ENST00000483569MGLLchr3

127500632

-EEFSECchr3

127965679

+
intron-3CDSENST00000476682ENST00000254730MGLLchr3

127500632

-EEFSECchr3

127965679

+
intron-3CDSENST00000476682ENST00000483457MGLLchr3

127500632

-EEFSECchr3

127965679

+
intron-intronENST00000476682ENST00000483569MGLLchr3

127500632

-EEFSECchr3

127965679

+
intron-3CDSENST00000398101ENST00000254730MGLLchr3

127500632

-EEFSECchr3

127965679

+
intron-3CDSENST00000398101ENST00000483457MGLLchr3

127500632

-EEFSECchr3

127965679

+
intron-intronENST00000398101ENST00000483569MGLLchr3

127500632

-EEFSECchr3

127965679

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000265052MGLLchr3127500631-ENST00000254730EEFSECchr3127965678+26608024862276596
ENST00000265052MGLLchr3127500631-ENST00000483457EEFSECchr3127965678+23388024861796436
ENST00000398104MGLLchr3127500631-ENST00000254730EEFSECchr3127965678+2235377611851596
ENST00000398104MGLLchr3127500631-ENST00000483457EEFSECchr3127965678+1913377611371436
ENST00000453507MGLLchr3127500631-ENST00000254730EEFSECchr3127965678+2153295331769578
ENST00000453507MGLLchr3127500631-ENST00000483457EEFSECchr3127965678+1831295331289418
ENST00000265052MGLLchr3127500632-ENST00000254730EEFSECchr3127965679+26608024862276596
ENST00000265052MGLLchr3127500632-ENST00000483457EEFSECchr3127965679+23388024861796436
ENST00000398104MGLLchr3127500632-ENST00000254730EEFSECchr3127965679+2235377611851596
ENST00000398104MGLLchr3127500632-ENST00000483457EEFSECchr3127965679+1913377611371436
ENST00000453507MGLLchr3127500632-ENST00000254730EEFSECchr3127965679+2153295331769578
ENST00000453507MGLLchr3127500632-ENST00000483457EEFSECchr3127965679+1831295331289418

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000265052ENST00000254730MGLLchr3127500631-EEFSECchr3127965678+0.0091826580.9908173
ENST00000265052ENST00000483457MGLLchr3127500631-EEFSECchr3127965678+0.0068506650.99314934
ENST00000398104ENST00000254730MGLLchr3127500631-EEFSECchr3127965678+0.0111457950.98885417
ENST00000398104ENST00000483457MGLLchr3127500631-EEFSECchr3127965678+0.0092009330.99079907
ENST00000453507ENST00000254730MGLLchr3127500631-EEFSECchr3127965678+0.0098396860.9901603
ENST00000453507ENST00000483457MGLLchr3127500631-EEFSECchr3127965678+0.0058565980.9941434
ENST00000265052ENST00000254730MGLLchr3127500632-EEFSECchr3127965679+0.0091826580.9908173
ENST00000265052ENST00000483457MGLLchr3127500632-EEFSECchr3127965679+0.0068506650.99314934
ENST00000398104ENST00000254730MGLLchr3127500632-EEFSECchr3127965679+0.0111457950.98885417
ENST00000398104ENST00000483457MGLLchr3127500632-EEFSECchr3127965679+0.0092009330.99079907
ENST00000453507ENST00000254730MGLLchr3127500632-EEFSECchr3127965679+0.0098396860.9901603
ENST00000453507ENST00000483457MGLLchr3127500632-EEFSECchr3127965679+0.0058565980.9941434

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Fusion Genomic Features for MGLL-EEFSEC


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for MGLL-EEFSEC


check button Go to

FGviewer for the breakpoints of chr3:127500631-chr3:127965678

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.EEFSEC

P57772

FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneEEFSECchr3:127500631chr3:127965678ENST0000025473007547_553105.33333333333333597.0MotifNuclear localization signal
TgeneEEFSECchr3:127500632chr3:127965679ENST0000025473007547_553105.33333333333333597.0MotifNuclear localization signal
TgeneEEFSECchr3:127500631chr3:127965678ENST0000025473007146_150105.33333333333333597.0Nucleotide bindingGTP
TgeneEEFSECchr3:127500632chr3:127965679ENST0000025473007146_150105.33333333333333597.0Nucleotide bindingGTP
TgeneEEFSECchr3:127500631chr3:127965678ENST0000025473007146_149105.33333333333333597.0RegionG4
TgeneEEFSECchr3:127500632chr3:127965679ENST0000025473007146_149105.33333333333333597.0RegionG4

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneEEFSECchr3:127500631chr3:127965678ENST00000254730075_217105.33333333333333597.0Domaintr-type G
TgeneEEFSECchr3:127500632chr3:127965679ENST00000254730075_217105.33333333333333597.0Domaintr-type G
TgeneEEFSECchr3:127500631chr3:127965678ENST000002547300792_96105.33333333333333597.0Nucleotide bindingGTP
TgeneEEFSECchr3:127500632chr3:127965679ENST000002547300792_96105.33333333333333597.0Nucleotide bindingGTP
TgeneEEFSECchr3:127500631chr3:127965678ENST000002547300714_21105.33333333333333597.0RegionG1
TgeneEEFSECchr3:127500631chr3:127965678ENST000002547300746_50105.33333333333333597.0RegionG2
TgeneEEFSECchr3:127500631chr3:127965678ENST000002547300792_95105.33333333333333597.0RegionG3
TgeneEEFSECchr3:127500632chr3:127965679ENST000002547300714_21105.33333333333333597.0RegionG1
TgeneEEFSECchr3:127500632chr3:127965679ENST000002547300746_50105.33333333333333597.0RegionG2
TgeneEEFSECchr3:127500632chr3:127965679ENST000002547300792_95105.33333333333333597.0RegionG3


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Fusion Gene Sequence for MGLL-EEFSEC


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000265052_ENST00000254730_TCGA-VR-A8Q7_MGLL_chr3_127500631_-_EEFSEC_chr3_127965678_length(transcript)=2660nt_BP=802nt
CTCCATCTTTCTAGTCCCCACCTTCCCCGGTGCAGACACCCGGCGAAGCCCACCCGGTTTTCCCAGCGGCATTTCCGATGACAGCTTCGG
GGCTACGTGTCCTGTGCTGTCGGAGACGCACAGGAAGCAAAGTTTGTGAGAAGCCTTGGGGGCGACTTTGCCTTGGGCACCCGCATTTGT
GCGTCTGCGAGGTGCCTCGGTGTGCGCGGAGCTAGTTTCCCAGTTTCCCGGGCCCCTCCCTTCTCCGAGCCCCTCTAGCGATTTGTTTAG
GAAAAGTGATGACATGAACTAGTAGTGGAGAATCGCAGCGCCGCTCCCCGCCCTGGGGAGGGAGGGGAGCCCCGGAGAGCCTGCCGGTGG
GAGCTGGAAGCAGGCTCCCGGCTGAGCGCCCCAGCCCGAAAGGCAGGGTCTGGGTGCGGGAAGAGGGCTCGGAGCTGCCTTCCTGCTGCC
TTGGGGCCGCCCAGATGAGGGAACAGCCCGATTTGCCTGGTTCTGATTCTCCAGGCTGTCGTGGTTGTGGAATGCAAACGCCAGCACATA
ATGGAAACAGGACCTGAAGACCCTTCCAGCATGCCAGAGGAAAGTTCCCCCAGGCGGACCCCGCAGAGCATTCCCTACCAGGACCTCCCT
CACCTGGTCAATGCAGACGGACAGTACCTCTTCTGCAGGTACTGGAAACCCACAGGCACACCCAAGGCCCTCATCTTTGTGTCCCATGGA
GCCGGAGAGCACAGTGGCCGCTATGAAGAGCTGGCTCGGATGCTGATGGGGCTGGACCTGCTGGTGTTCGCCCACGACCATGGGGCCCAG
ATCATTGATCTGATGATGCTGGTCATCGATGTGACCAAGGGGATGCAGACCCAGTCAGCGGAATGCCTTGTGATCGGCCAGATTGCCTGC
CAGAAGCTGGTCGTGGTGCTGAACAAAATAGACCTCTTACCTGAAGGAAAGAGACAGGCAGCAATTGATAAAATGACCAAGAAAATGCAG
AAGACCCTAGAGAACACCAAGTTCCGAGGTGCACCGATTATACCCGTGGCGGCCAAGCCGGGGGGACCAGAGGCCCCCGAAACTGAAGCT
CCACAGGGCATTCCAGAGCTCATTGAGCTCCTGACGTCCCAGATTTCCATCCCAACGAGAGATCCCTCGGGACCGTTCCTCATGTCTGTG
GACCACTGTTTCTCCATCAAAGGCCAAGGCACTGTGATGACAGGGACCATCCTTTCAGGCTCCATCAGCCTCGGTGACAGTGTGGAGATC
CCTGCCCTCAAGGTGGTGAAGAAGGTGAAGTCCATGCAGATGTTCCACATGCCCATCACTTCAGCCATGCAAGGAGACCGGCTGGGCATC
TGCGTCACCCAGTTTGACCCTAAGCTGCTGGAGCGCGGGTTGGTGTGTGCCCCCGAGTCCCTGCACACTGTCCATGCGGCCCTCATCTCT
GTGGAAAAGATACCGTATTTCCGGGGGCCCCTGCAAACCAAGGCCAAGTTCCACATTACAGTGGGCCATGAAACAGTCATGGGCCGGTTG
ATGTTCTTCAGTCCTGCTCCAGATAACTTTGACCAGGAGCCTATACTGGACTCTTTCAACTTCTCTCAAGAATACCTTTTCCAGGAGCAG
TACCTGTCCAAGGATTTGACACCAGCAGTGACAGACAATGATGAGGCCGACAAGAAGGCCGGCCAGGCCACAGAGGGCCATTGTCCTCGG
CAGCAGTGGGCCCTGGTGGAGTTTGAGAAGCCCGTCACCTGCCCTCGGCTGTGCCTGGTGATTGGCTCCAGGCTAGATGCGGACATTCAC
ACCAACACGTGCCGGCTAGCCTTCCATGGCATCCTGCTCCACGGGCTAGAGGACAGGAACTACGCCGACAGCTTCCTGCCCAGGCTGAAG
GTGTACAAGCTGAAGCACAAGCATGGCCTTGTGGAGCGGGCGATGGATGACTACAGTGTGATCGGCCGCTCCCTGTTCAAAAAGGAAACC
AACATCCAGCTCTTCGTGGGGCTCAAGGTGCACTTGTCCACTGGGGAACTGGGCATCATCGACAGTGCCTTCGGCCAGAGCGGCAAGTTC
AAGATCCACATCCCAGGTGGCCTCAGCCCCGAGTCCAAGAAGATCCTGACACCCGCCCTCAAGAAGCGGGCCCGGGCTGGCCGTGGGGAG
GCCACCAGGCAGGAGGAGAGCGCCGAGCGGAGCGAGCCCTCACAGCATGTGGTGCTCAGCCTGACTTTCAAGCGTTATGTCTTCGACACC
CACAAGCGCATGGTTCAGTCTCCCTGAGTGTCCGGTGACCTCCCCCAGGGCCTCCTTGCCCAGCCCAGTCCAGGCTGCTGTGCCAAATCC
CAACCAGCCACGCCTCAGCCTCTCCCAGTCTCTCCCTGCAGTCCTGCAGCAGCAGCCCCCACCCCCAAGCTTGGTGCTGAGCCCTGGTGA
GGAGCTGAGGGGGATGGGTTGCTGGGGCCAGGAGGGTCTCTCCTCCAGCCCCTGCACACTCCCACCCAGGACAGCCCCCAGCCCAACTAG
GAAAGGGCCATGGGCAGAGGGCTGGTAGCCAGTATCTTCCACTGCCCCATCTGTTGGCCACCTGCAGGCCAGTCTCAACCCTCCCCCAGG

>In-frame_ENST00000265052_ENST00000254730_TCGA-VR-A8Q7_MGLL_chr3_127500631_-_EEFSEC_chr3_127965678_length(amino acids)=596AA_start in transcript=486_stop in transcript=2276
MVLILQAVVVVECKRQHIMETGPEDPSSMPEESSPRRTPQSIPYQDLPHLVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEELA
RMLMGLDLLVFAHDHGAQIIDLMMLVIDVTKGMQTQSAECLVIGQIACQKLVVVLNKIDLLPEGKRQAAIDKMTKKMQKTLENTKFRGAP
IIPVAAKPGGPEAPETEAPQGIPELIELLTSQISIPTRDPSGPFLMSVDHCFSIKGQGTVMTGTILSGSISLGDSVEIPALKVVKKVKSM
QMFHMPITSAMQGDRLGICVTQFDPKLLERGLVCAPESLHTVHAALISVEKIPYFRGPLQTKAKFHITVGHETVMGRLMFFSPAPDNFDQ
EPILDSFNFSQEYLFQEQYLSKDLTPAVTDNDEADKKAGQATEGHCPRQQWALVEFEKPVTCPRLCLVIGSRLDADIHTNTCRLAFHGIL
LHGLEDRNYADSFLPRLKVYKLKHKHGLVERAMDDYSVIGRSLFKKETNIQLFVGLKVHLSTGELGIIDSAFGQSGKFKIHIPGGLSPES

--------------------------------------------------------------
>In-frame_ENST00000265052_ENST00000483457_TCGA-VR-A8Q7_MGLL_chr3_127500631_-_EEFSEC_chr3_127965678_length(transcript)=2338nt_BP=802nt
CTCCATCTTTCTAGTCCCCACCTTCCCCGGTGCAGACACCCGGCGAAGCCCACCCGGTTTTCCCAGCGGCATTTCCGATGACAGCTTCGG
GGCTACGTGTCCTGTGCTGTCGGAGACGCACAGGAAGCAAAGTTTGTGAGAAGCCTTGGGGGCGACTTTGCCTTGGGCACCCGCATTTGT
GCGTCTGCGAGGTGCCTCGGTGTGCGCGGAGCTAGTTTCCCAGTTTCCCGGGCCCCTCCCTTCTCCGAGCCCCTCTAGCGATTTGTTTAG
GAAAAGTGATGACATGAACTAGTAGTGGAGAATCGCAGCGCCGCTCCCCGCCCTGGGGAGGGAGGGGAGCCCCGGAGAGCCTGCCGGTGG
GAGCTGGAAGCAGGCTCCCGGCTGAGCGCCCCAGCCCGAAAGGCAGGGTCTGGGTGCGGGAAGAGGGCTCGGAGCTGCCTTCCTGCTGCC
TTGGGGCCGCCCAGATGAGGGAACAGCCCGATTTGCCTGGTTCTGATTCTCCAGGCTGTCGTGGTTGTGGAATGCAAACGCCAGCACATA
ATGGAAACAGGACCTGAAGACCCTTCCAGCATGCCAGAGGAAAGTTCCCCCAGGCGGACCCCGCAGAGCATTCCCTACCAGGACCTCCCT
CACCTGGTCAATGCAGACGGACAGTACCTCTTCTGCAGGTACTGGAAACCCACAGGCACACCCAAGGCCCTCATCTTTGTGTCCCATGGA
GCCGGAGAGCACAGTGGCCGCTATGAAGAGCTGGCTCGGATGCTGATGGGGCTGGACCTGCTGGTGTTCGCCCACGACCATGGGGCCCAG
ATCATTGATCTGATGATGCTGGTCATCGATGTGACCAAGGGGATGCAGACCCAGTCAGCGGAATGCCTTGTGATCGGCCAGATTGCCTGC
CAGAAGCTGGTCGTGGTGCTGAACAAAATAGACCTCTTACCTGAAGGAAAGAGACAGGCAGCAATTGATAAAATGACCAAGAAAATGCAG
AAGACCCTAGAGAACACCAAGTTCCGAGGTGCACCGATTATACCCGTGGCGGCCAAGCCGGGGGGACCAGAGGCCCCCGAAACTGAAGCT
CCACAGGGCATTCCAGAGCTCATTGAGGTGGTGAAGAAGGTGAAGTCCATGCAGATGTTCCACATGCCCATCACTTCAGCCATGCAAGGA
GACCGGCTGGGCATCTGCGTCACCCAGTTTGACCCTAAGCTGCTGGAGCGCGGGTTGGTGTGTGCCCCCGAGTCCCTGCACACTGTCCAT
GCGGCCCTCATCTCTGTGGAAAAGATACCGTATTTCCGGGGGCCCCTGCAAACCAAGGCCAAGTTCCACATTACAGTGGGCCATGAAACA
GTCATGGGCCGGTTGATGTTCTTCAGTCCTGCTCCAGATAACTTTGACCAGGAGCCTATACTGGACTCTTTCAACTTCTCTCAAGAATAC
CTTTTCCAGGAGCAGTACCTGTCCAAGGATTTGACACCAGCAGTGACAGACAATGATGAGGCCGACAAGAAGGCCGGCCAGGCCACAGAG
GGCCATTGTCCTCGGCAGCAGTGGGCCCTGGTGGAGTTTGAGAAGCCCGTCACCTGCCCTCGGCTGTGCCTGGTGATTGGCTCCAGGCTA
GATGCGGACATTCACACCAACACGTGCCGGCTAGCCTTCCATGGCATCCTGCTCCACGGGCTAGAGGACAGGAACTACGCCGACAGCTTC
CTGCCCAGGCTGAAGGTGTACAAGCTGAAGCACAAGCATGGCCTTGTGGAGCGGGTGGCCTCAGCCCCGAGTCCAAGAAGATCCTGACAC
CCGCCCTCAAGAAGCGGGCCCGGGCTGGCCGTGGGGAGGCCACCAGGCAGGAGGAGAGCGCCGAGCGGAGCGAGCCCTCACAGCATGTGG
TGCTCAGCCTGACTTTCAAGCGTTATGTCTTCGACACCCACAAGCGCATGGTTCAGTCTCCCTGAGTGTCCGGTGACCTCCCCCAGGGCC
TCCTTGCCCAGCCCAGTCCAGGCTGCTGTGCCAAATCCCAACCAGCCACGCCTCAGCCTCTCCCAGTCTCTCCCTGCAGTCCTGCAGCAG
CAGCCCCCACCCCCAAGCTTGGTGCTGAGCCCTGGTGAGGAGCTGAGGGGGATGGGTTGCTGGGGCCAGGAGGGTCTCTCCTCCAGCCCC
TGCACACTCCCACCCAGGACAGCCCCCAGCCCAACTAGGAAAGGGCCATGGGCAGAGGGCTGGTAGCCAGTATCTTCCACTGCCCCATCT

>In-frame_ENST00000265052_ENST00000483457_TCGA-VR-A8Q7_MGLL_chr3_127500631_-_EEFSEC_chr3_127965678_length(amino acids)=436AA_start in transcript=486_stop in transcript=1796
MVLILQAVVVVECKRQHIMETGPEDPSSMPEESSPRRTPQSIPYQDLPHLVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEELA
RMLMGLDLLVFAHDHGAQIIDLMMLVIDVTKGMQTQSAECLVIGQIACQKLVVVLNKIDLLPEGKRQAAIDKMTKKMQKTLENTKFRGAP
IIPVAAKPGGPEAPETEAPQGIPELIEVVKKVKSMQMFHMPITSAMQGDRLGICVTQFDPKLLERGLVCAPESLHTVHAALISVEKIPYF
RGPLQTKAKFHITVGHETVMGRLMFFSPAPDNFDQEPILDSFNFSQEYLFQEQYLSKDLTPAVTDNDEADKKAGQATEGHCPRQQWALVE

--------------------------------------------------------------
>In-frame_ENST00000398104_ENST00000254730_TCGA-VR-A8Q7_MGLL_chr3_127500631_-_EEFSEC_chr3_127965678_length(transcript)=2235nt_BP=377nt
TGGCGGCGCAGACGCCGCACCCTGTCGCCGCGAAGCCGGTCGCGCGCAGCTCGTCCCGGCCCTGGCCCGCCGCAAACGAGGATCCGCTGC
GCTCGGGGAACGCGACAGCGGCGCTCGTGGCCCCGGACCTGAAGACCCTTCCAGCATGCCAGAGGAAAGTTCCCCCAGGCGGACCCCGCA
GAGCATTCCCTACCAGGACCTCCCTCACCTGGTCAATGCAGACGGACAGTACCTCTTCTGCAGGTACTGGAAACCCACAGGCACACCCAA
GGCCCTCATCTTTGTGTCCCATGGAGCCGGAGAGCACAGTGGCCGCTATGAAGAGCTGGCTCGGATGCTGATGGGGCTGGACCTGCTGGT
GTTCGCCCACGACCATGGGGCCCAGATCATTGATCTGATGATGCTGGTCATCGATGTGACCAAGGGGATGCAGACCCAGTCAGCGGAATG
CCTTGTGATCGGCCAGATTGCCTGCCAGAAGCTGGTCGTGGTGCTGAACAAAATAGACCTCTTACCTGAAGGAAAGAGACAGGCAGCAAT
TGATAAAATGACCAAGAAAATGCAGAAGACCCTAGAGAACACCAAGTTCCGAGGTGCACCGATTATACCCGTGGCGGCCAAGCCGGGGGG
ACCAGAGGCCCCCGAAACTGAAGCTCCACAGGGCATTCCAGAGCTCATTGAGCTCCTGACGTCCCAGATTTCCATCCCAACGAGAGATCC
CTCGGGACCGTTCCTCATGTCTGTGGACCACTGTTTCTCCATCAAAGGCCAAGGCACTGTGATGACAGGGACCATCCTTTCAGGCTCCAT
CAGCCTCGGTGACAGTGTGGAGATCCCTGCCCTCAAGGTGGTGAAGAAGGTGAAGTCCATGCAGATGTTCCACATGCCCATCACTTCAGC
CATGCAAGGAGACCGGCTGGGCATCTGCGTCACCCAGTTTGACCCTAAGCTGCTGGAGCGCGGGTTGGTGTGTGCCCCCGAGTCCCTGCA
CACTGTCCATGCGGCCCTCATCTCTGTGGAAAAGATACCGTATTTCCGGGGGCCCCTGCAAACCAAGGCCAAGTTCCACATTACAGTGGG
CCATGAAACAGTCATGGGCCGGTTGATGTTCTTCAGTCCTGCTCCAGATAACTTTGACCAGGAGCCTATACTGGACTCTTTCAACTTCTC
TCAAGAATACCTTTTCCAGGAGCAGTACCTGTCCAAGGATTTGACACCAGCAGTGACAGACAATGATGAGGCCGACAAGAAGGCCGGCCA
GGCCACAGAGGGCCATTGTCCTCGGCAGCAGTGGGCCCTGGTGGAGTTTGAGAAGCCCGTCACCTGCCCTCGGCTGTGCCTGGTGATTGG
CTCCAGGCTAGATGCGGACATTCACACCAACACGTGCCGGCTAGCCTTCCATGGCATCCTGCTCCACGGGCTAGAGGACAGGAACTACGC
CGACAGCTTCCTGCCCAGGCTGAAGGTGTACAAGCTGAAGCACAAGCATGGCCTTGTGGAGCGGGCGATGGATGACTACAGTGTGATCGG
CCGCTCCCTGTTCAAAAAGGAAACCAACATCCAGCTCTTCGTGGGGCTCAAGGTGCACTTGTCCACTGGGGAACTGGGCATCATCGACAG
TGCCTTCGGCCAGAGCGGCAAGTTCAAGATCCACATCCCAGGTGGCCTCAGCCCCGAGTCCAAGAAGATCCTGACACCCGCCCTCAAGAA
GCGGGCCCGGGCTGGCCGTGGGGAGGCCACCAGGCAGGAGGAGAGCGCCGAGCGGAGCGAGCCCTCACAGCATGTGGTGCTCAGCCTGAC
TTTCAAGCGTTATGTCTTCGACACCCACAAGCGCATGGTTCAGTCTCCCTGAGTGTCCGGTGACCTCCCCCAGGGCCTCCTTGCCCAGCC
CAGTCCAGGCTGCTGTGCCAAATCCCAACCAGCCACGCCTCAGCCTCTCCCAGTCTCTCCCTGCAGTCCTGCAGCAGCAGCCCCCACCCC
CAAGCTTGGTGCTGAGCCCTGGTGAGGAGCTGAGGGGGATGGGTTGCTGGGGCCAGGAGGGTCTCTCCTCCAGCCCCTGCACACTCCCAC
CCAGGACAGCCCCCAGCCCAACTAGGAAAGGGCCATGGGCAGAGGGCTGGTAGCCAGTATCTTCCACTGCCCCATCTGTTGGCCACCTGC

>In-frame_ENST00000398104_ENST00000254730_TCGA-VR-A8Q7_MGLL_chr3_127500631_-_EEFSEC_chr3_127965678_length(amino acids)=596AA_start in transcript=61_stop in transcript=1851
MARRKRGSAALGERDSGARGPGPEDPSSMPEESSPRRTPQSIPYQDLPHLVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEELA
RMLMGLDLLVFAHDHGAQIIDLMMLVIDVTKGMQTQSAECLVIGQIACQKLVVVLNKIDLLPEGKRQAAIDKMTKKMQKTLENTKFRGAP
IIPVAAKPGGPEAPETEAPQGIPELIELLTSQISIPTRDPSGPFLMSVDHCFSIKGQGTVMTGTILSGSISLGDSVEIPALKVVKKVKSM
QMFHMPITSAMQGDRLGICVTQFDPKLLERGLVCAPESLHTVHAALISVEKIPYFRGPLQTKAKFHITVGHETVMGRLMFFSPAPDNFDQ
EPILDSFNFSQEYLFQEQYLSKDLTPAVTDNDEADKKAGQATEGHCPRQQWALVEFEKPVTCPRLCLVIGSRLDADIHTNTCRLAFHGIL
LHGLEDRNYADSFLPRLKVYKLKHKHGLVERAMDDYSVIGRSLFKKETNIQLFVGLKVHLSTGELGIIDSAFGQSGKFKIHIPGGLSPES

--------------------------------------------------------------
>In-frame_ENST00000398104_ENST00000483457_TCGA-VR-A8Q7_MGLL_chr3_127500631_-_EEFSEC_chr3_127965678_length(transcript)=1913nt_BP=377nt
TGGCGGCGCAGACGCCGCACCCTGTCGCCGCGAAGCCGGTCGCGCGCAGCTCGTCCCGGCCCTGGCCCGCCGCAAACGAGGATCCGCTGC
GCTCGGGGAACGCGACAGCGGCGCTCGTGGCCCCGGACCTGAAGACCCTTCCAGCATGCCAGAGGAAAGTTCCCCCAGGCGGACCCCGCA
GAGCATTCCCTACCAGGACCTCCCTCACCTGGTCAATGCAGACGGACAGTACCTCTTCTGCAGGTACTGGAAACCCACAGGCACACCCAA
GGCCCTCATCTTTGTGTCCCATGGAGCCGGAGAGCACAGTGGCCGCTATGAAGAGCTGGCTCGGATGCTGATGGGGCTGGACCTGCTGGT
GTTCGCCCACGACCATGGGGCCCAGATCATTGATCTGATGATGCTGGTCATCGATGTGACCAAGGGGATGCAGACCCAGTCAGCGGAATG
CCTTGTGATCGGCCAGATTGCCTGCCAGAAGCTGGTCGTGGTGCTGAACAAAATAGACCTCTTACCTGAAGGAAAGAGACAGGCAGCAAT
TGATAAAATGACCAAGAAAATGCAGAAGACCCTAGAGAACACCAAGTTCCGAGGTGCACCGATTATACCCGTGGCGGCCAAGCCGGGGGG
ACCAGAGGCCCCCGAAACTGAAGCTCCACAGGGCATTCCAGAGCTCATTGAGGTGGTGAAGAAGGTGAAGTCCATGCAGATGTTCCACAT
GCCCATCACTTCAGCCATGCAAGGAGACCGGCTGGGCATCTGCGTCACCCAGTTTGACCCTAAGCTGCTGGAGCGCGGGTTGGTGTGTGC
CCCCGAGTCCCTGCACACTGTCCATGCGGCCCTCATCTCTGTGGAAAAGATACCGTATTTCCGGGGGCCCCTGCAAACCAAGGCCAAGTT
CCACATTACAGTGGGCCATGAAACAGTCATGGGCCGGTTGATGTTCTTCAGTCCTGCTCCAGATAACTTTGACCAGGAGCCTATACTGGA
CTCTTTCAACTTCTCTCAAGAATACCTTTTCCAGGAGCAGTACCTGTCCAAGGATTTGACACCAGCAGTGACAGACAATGATGAGGCCGA
CAAGAAGGCCGGCCAGGCCACAGAGGGCCATTGTCCTCGGCAGCAGTGGGCCCTGGTGGAGTTTGAGAAGCCCGTCACCTGCCCTCGGCT
GTGCCTGGTGATTGGCTCCAGGCTAGATGCGGACATTCACACCAACACGTGCCGGCTAGCCTTCCATGGCATCCTGCTCCACGGGCTAGA
GGACAGGAACTACGCCGACAGCTTCCTGCCCAGGCTGAAGGTGTACAAGCTGAAGCACAAGCATGGCCTTGTGGAGCGGGTGGCCTCAGC
CCCGAGTCCAAGAAGATCCTGACACCCGCCCTCAAGAAGCGGGCCCGGGCTGGCCGTGGGGAGGCCACCAGGCAGGAGGAGAGCGCCGAG
CGGAGCGAGCCCTCACAGCATGTGGTGCTCAGCCTGACTTTCAAGCGTTATGTCTTCGACACCCACAAGCGCATGGTTCAGTCTCCCTGA
GTGTCCGGTGACCTCCCCCAGGGCCTCCTTGCCCAGCCCAGTCCAGGCTGCTGTGCCAAATCCCAACCAGCCACGCCTCAGCCTCTCCCA
GTCTCTCCCTGCAGTCCTGCAGCAGCAGCCCCCACCCCCAAGCTTGGTGCTGAGCCCTGGTGAGGAGCTGAGGGGGATGGGTTGCTGGGG
CCAGGAGGGTCTCTCCTCCAGCCCCTGCACACTCCCACCCAGGACAGCCCCCAGCCCAACTAGGAAAGGGCCATGGGCAGAGGGCTGGTA
GCCAGTATCTTCCACTGCCCCATCTGTTGGCCACCTGCAGGCCAGTCTCAACCCTCCCCCAGGTGGGCAGGCACTTGATGGCTACAAATA

>In-frame_ENST00000398104_ENST00000483457_TCGA-VR-A8Q7_MGLL_chr3_127500631_-_EEFSEC_chr3_127965678_length(amino acids)=436AA_start in transcript=61_stop in transcript=1371
MARRKRGSAALGERDSGARGPGPEDPSSMPEESSPRRTPQSIPYQDLPHLVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEELA
RMLMGLDLLVFAHDHGAQIIDLMMLVIDVTKGMQTQSAECLVIGQIACQKLVVVLNKIDLLPEGKRQAAIDKMTKKMQKTLENTKFRGAP
IIPVAAKPGGPEAPETEAPQGIPELIEVVKKVKSMQMFHMPITSAMQGDRLGICVTQFDPKLLERGLVCAPESLHTVHAALISVEKIPYF
RGPLQTKAKFHITVGHETVMGRLMFFSPAPDNFDQEPILDSFNFSQEYLFQEQYLSKDLTPAVTDNDEADKKAGQATEGHCPRQQWALVE

--------------------------------------------------------------
>In-frame_ENST00000453507_ENST00000254730_TCGA-VR-A8Q7_MGLL_chr3_127500631_-_EEFSEC_chr3_127965678_length(transcript)=2153nt_BP=295nt
GTCGTGGTTGTGGAATGCAAACGCCAGCACATAATGGAAACAGGACCTGAAGACCCTTCCAGCATGCCAGAGGAAAGTTCCCCCAGGCGG
ACCCCGCAGAGCATTCCCTACCAGGACCTCCCTCACCTGGTCAATGCAGACGGACAGTACCTCTTCTGCAGGTACTGGAAACCCACAGGC
ACACCCAAGGCCCTCATCTTTGTGTCCCATGGAGCCGGAGAGCACAGTGGCCGCTATGAAGAGCTGGCTCGGATGCTGATGGGGCTGGAC
CTGCTGGTGTTCGCCCACGACCATGGGGCCCAGATCATTGATCTGATGATGCTGGTCATCGATGTGACCAAGGGGATGCAGACCCAGTCA
GCGGAATGCCTTGTGATCGGCCAGATTGCCTGCCAGAAGCTGGTCGTGGTGCTGAACAAAATAGACCTCTTACCTGAAGGAAAGAGACAG
GCAGCAATTGATAAAATGACCAAGAAAATGCAGAAGACCCTAGAGAACACCAAGTTCCGAGGTGCACCGATTATACCCGTGGCGGCCAAG
CCGGGGGGACCAGAGGCCCCCGAAACTGAAGCTCCACAGGGCATTCCAGAGCTCATTGAGCTCCTGACGTCCCAGATTTCCATCCCAACG
AGAGATCCCTCGGGACCGTTCCTCATGTCTGTGGACCACTGTTTCTCCATCAAAGGCCAAGGCACTGTGATGACAGGGACCATCCTTTCA
GGCTCCATCAGCCTCGGTGACAGTGTGGAGATCCCTGCCCTCAAGGTGGTGAAGAAGGTGAAGTCCATGCAGATGTTCCACATGCCCATC
ACTTCAGCCATGCAAGGAGACCGGCTGGGCATCTGCGTCACCCAGTTTGACCCTAAGCTGCTGGAGCGCGGGTTGGTGTGTGCCCCCGAG
TCCCTGCACACTGTCCATGCGGCCCTCATCTCTGTGGAAAAGATACCGTATTTCCGGGGGCCCCTGCAAACCAAGGCCAAGTTCCACATT
ACAGTGGGCCATGAAACAGTCATGGGCCGGTTGATGTTCTTCAGTCCTGCTCCAGATAACTTTGACCAGGAGCCTATACTGGACTCTTTC
AACTTCTCTCAAGAATACCTTTTCCAGGAGCAGTACCTGTCCAAGGATTTGACACCAGCAGTGACAGACAATGATGAGGCCGACAAGAAG
GCCGGCCAGGCCACAGAGGGCCATTGTCCTCGGCAGCAGTGGGCCCTGGTGGAGTTTGAGAAGCCCGTCACCTGCCCTCGGCTGTGCCTG
GTGATTGGCTCCAGGCTAGATGCGGACATTCACACCAACACGTGCCGGCTAGCCTTCCATGGCATCCTGCTCCACGGGCTAGAGGACAGG
AACTACGCCGACAGCTTCCTGCCCAGGCTGAAGGTGTACAAGCTGAAGCACAAGCATGGCCTTGTGGAGCGGGCGATGGATGACTACAGT
GTGATCGGCCGCTCCCTGTTCAAAAAGGAAACCAACATCCAGCTCTTCGTGGGGCTCAAGGTGCACTTGTCCACTGGGGAACTGGGCATC
ATCGACAGTGCCTTCGGCCAGAGCGGCAAGTTCAAGATCCACATCCCAGGTGGCCTCAGCCCCGAGTCCAAGAAGATCCTGACACCCGCC
CTCAAGAAGCGGGCCCGGGCTGGCCGTGGGGAGGCCACCAGGCAGGAGGAGAGCGCCGAGCGGAGCGAGCCCTCACAGCATGTGGTGCTC
AGCCTGACTTTCAAGCGTTATGTCTTCGACACCCACAAGCGCATGGTTCAGTCTCCCTGAGTGTCCGGTGACCTCCCCCAGGGCCTCCTT
GCCCAGCCCAGTCCAGGCTGCTGTGCCAAATCCCAACCAGCCACGCCTCAGCCTCTCCCAGTCTCTCCCTGCAGTCCTGCAGCAGCAGCC
CCCACCCCCAAGCTTGGTGCTGAGCCCTGGTGAGGAGCTGAGGGGGATGGGTTGCTGGGGCCAGGAGGGTCTCTCCTCCAGCCCCTGCAC
ACTCCCACCCAGGACAGCCCCCAGCCCAACTAGGAAAGGGCCATGGGCAGAGGGCTGGTAGCCAGTATCTTCCACTGCCCCATCTGTTGG

>In-frame_ENST00000453507_ENST00000254730_TCGA-VR-A8Q7_MGLL_chr3_127500631_-_EEFSEC_chr3_127965678_length(amino acids)=578AA_start in transcript=33_stop in transcript=1769
METGPEDPSSMPEESSPRRTPQSIPYQDLPHLVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHGAQ
IIDLMMLVIDVTKGMQTQSAECLVIGQIACQKLVVVLNKIDLLPEGKRQAAIDKMTKKMQKTLENTKFRGAPIIPVAAKPGGPEAPETEA
PQGIPELIELLTSQISIPTRDPSGPFLMSVDHCFSIKGQGTVMTGTILSGSISLGDSVEIPALKVVKKVKSMQMFHMPITSAMQGDRLGI
CVTQFDPKLLERGLVCAPESLHTVHAALISVEKIPYFRGPLQTKAKFHITVGHETVMGRLMFFSPAPDNFDQEPILDSFNFSQEYLFQEQ
YLSKDLTPAVTDNDEADKKAGQATEGHCPRQQWALVEFEKPVTCPRLCLVIGSRLDADIHTNTCRLAFHGILLHGLEDRNYADSFLPRLK
VYKLKHKHGLVERAMDDYSVIGRSLFKKETNIQLFVGLKVHLSTGELGIIDSAFGQSGKFKIHIPGGLSPESKKILTPALKKRARAGRGE

--------------------------------------------------------------
>In-frame_ENST00000453507_ENST00000483457_TCGA-VR-A8Q7_MGLL_chr3_127500631_-_EEFSEC_chr3_127965678_length(transcript)=1831nt_BP=295nt
GTCGTGGTTGTGGAATGCAAACGCCAGCACATAATGGAAACAGGACCTGAAGACCCTTCCAGCATGCCAGAGGAAAGTTCCCCCAGGCGG
ACCCCGCAGAGCATTCCCTACCAGGACCTCCCTCACCTGGTCAATGCAGACGGACAGTACCTCTTCTGCAGGTACTGGAAACCCACAGGC
ACACCCAAGGCCCTCATCTTTGTGTCCCATGGAGCCGGAGAGCACAGTGGCCGCTATGAAGAGCTGGCTCGGATGCTGATGGGGCTGGAC
CTGCTGGTGTTCGCCCACGACCATGGGGCCCAGATCATTGATCTGATGATGCTGGTCATCGATGTGACCAAGGGGATGCAGACCCAGTCA
GCGGAATGCCTTGTGATCGGCCAGATTGCCTGCCAGAAGCTGGTCGTGGTGCTGAACAAAATAGACCTCTTACCTGAAGGAAAGAGACAG
GCAGCAATTGATAAAATGACCAAGAAAATGCAGAAGACCCTAGAGAACACCAAGTTCCGAGGTGCACCGATTATACCCGTGGCGGCCAAG
CCGGGGGGACCAGAGGCCCCCGAAACTGAAGCTCCACAGGGCATTCCAGAGCTCATTGAGGTGGTGAAGAAGGTGAAGTCCATGCAGATG
TTCCACATGCCCATCACTTCAGCCATGCAAGGAGACCGGCTGGGCATCTGCGTCACCCAGTTTGACCCTAAGCTGCTGGAGCGCGGGTTG
GTGTGTGCCCCCGAGTCCCTGCACACTGTCCATGCGGCCCTCATCTCTGTGGAAAAGATACCGTATTTCCGGGGGCCCCTGCAAACCAAG
GCCAAGTTCCACATTACAGTGGGCCATGAAACAGTCATGGGCCGGTTGATGTTCTTCAGTCCTGCTCCAGATAACTTTGACCAGGAGCCT
ATACTGGACTCTTTCAACTTCTCTCAAGAATACCTTTTCCAGGAGCAGTACCTGTCCAAGGATTTGACACCAGCAGTGACAGACAATGAT
GAGGCCGACAAGAAGGCCGGCCAGGCCACAGAGGGCCATTGTCCTCGGCAGCAGTGGGCCCTGGTGGAGTTTGAGAAGCCCGTCACCTGC
CCTCGGCTGTGCCTGGTGATTGGCTCCAGGCTAGATGCGGACATTCACACCAACACGTGCCGGCTAGCCTTCCATGGCATCCTGCTCCAC
GGGCTAGAGGACAGGAACTACGCCGACAGCTTCCTGCCCAGGCTGAAGGTGTACAAGCTGAAGCACAAGCATGGCCTTGTGGAGCGGGTG
GCCTCAGCCCCGAGTCCAAGAAGATCCTGACACCCGCCCTCAAGAAGCGGGCCCGGGCTGGCCGTGGGGAGGCCACCAGGCAGGAGGAGA
GCGCCGAGCGGAGCGAGCCCTCACAGCATGTGGTGCTCAGCCTGACTTTCAAGCGTTATGTCTTCGACACCCACAAGCGCATGGTTCAGT
CTCCCTGAGTGTCCGGTGACCTCCCCCAGGGCCTCCTTGCCCAGCCCAGTCCAGGCTGCTGTGCCAAATCCCAACCAGCCACGCCTCAGC
CTCTCCCAGTCTCTCCCTGCAGTCCTGCAGCAGCAGCCCCCACCCCCAAGCTTGGTGCTGAGCCCTGGTGAGGAGCTGAGGGGGATGGGT
TGCTGGGGCCAGGAGGGTCTCTCCTCCAGCCCCTGCACACTCCCACCCAGGACAGCCCCCAGCCCAACTAGGAAAGGGCCATGGGCAGAG
GGCTGGTAGCCAGTATCTTCCACTGCCCCATCTGTTGGCCACCTGCAGGCCAGTCTCAACCCTCCCCCAGGTGGGCAGGCACTTGATGGC

>In-frame_ENST00000453507_ENST00000483457_TCGA-VR-A8Q7_MGLL_chr3_127500631_-_EEFSEC_chr3_127965678_length(amino acids)=418AA_start in transcript=33_stop in transcript=1289
METGPEDPSSMPEESSPRRTPQSIPYQDLPHLVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHGAQ
IIDLMMLVIDVTKGMQTQSAECLVIGQIACQKLVVVLNKIDLLPEGKRQAAIDKMTKKMQKTLENTKFRGAPIIPVAAKPGGPEAPETEA
PQGIPELIEVVKKVKSMQMFHMPITSAMQGDRLGICVTQFDPKLLERGLVCAPESLHTVHAALISVEKIPYFRGPLQTKAKFHITVGHET
VMGRLMFFSPAPDNFDQEPILDSFNFSQEYLFQEQYLSKDLTPAVTDNDEADKKAGQATEGHCPRQQWALVEFEKPVTCPRLCLVIGSRL

--------------------------------------------------------------
>In-frame_ENST00000265052_ENST00000254730_TCGA-BR-8058-01A_MGLL_chr3_127500632_-_EEFSEC_chr3_127965679_length(transcript)=2660nt_BP=802nt
CTCCATCTTTCTAGTCCCCACCTTCCCCGGTGCAGACACCCGGCGAAGCCCACCCGGTTTTCCCAGCGGCATTTCCGATGACAGCTTCGG
GGCTACGTGTCCTGTGCTGTCGGAGACGCACAGGAAGCAAAGTTTGTGAGAAGCCTTGGGGGCGACTTTGCCTTGGGCACCCGCATTTGT
GCGTCTGCGAGGTGCCTCGGTGTGCGCGGAGCTAGTTTCCCAGTTTCCCGGGCCCCTCCCTTCTCCGAGCCCCTCTAGCGATTTGTTTAG
GAAAAGTGATGACATGAACTAGTAGTGGAGAATCGCAGCGCCGCTCCCCGCCCTGGGGAGGGAGGGGAGCCCCGGAGAGCCTGCCGGTGG
GAGCTGGAAGCAGGCTCCCGGCTGAGCGCCCCAGCCCGAAAGGCAGGGTCTGGGTGCGGGAAGAGGGCTCGGAGCTGCCTTCCTGCTGCC
TTGGGGCCGCCCAGATGAGGGAACAGCCCGATTTGCCTGGTTCTGATTCTCCAGGCTGTCGTGGTTGTGGAATGCAAACGCCAGCACATA
ATGGAAACAGGACCTGAAGACCCTTCCAGCATGCCAGAGGAAAGTTCCCCCAGGCGGACCCCGCAGAGCATTCCCTACCAGGACCTCCCT
CACCTGGTCAATGCAGACGGACAGTACCTCTTCTGCAGGTACTGGAAACCCACAGGCACACCCAAGGCCCTCATCTTTGTGTCCCATGGA
GCCGGAGAGCACAGTGGCCGCTATGAAGAGCTGGCTCGGATGCTGATGGGGCTGGACCTGCTGGTGTTCGCCCACGACCATGGGGCCCAG
ATCATTGATCTGATGATGCTGGTCATCGATGTGACCAAGGGGATGCAGACCCAGTCAGCGGAATGCCTTGTGATCGGCCAGATTGCCTGC
CAGAAGCTGGTCGTGGTGCTGAACAAAATAGACCTCTTACCTGAAGGAAAGAGACAGGCAGCAATTGATAAAATGACCAAGAAAATGCAG
AAGACCCTAGAGAACACCAAGTTCCGAGGTGCACCGATTATACCCGTGGCGGCCAAGCCGGGGGGACCAGAGGCCCCCGAAACTGAAGCT
CCACAGGGCATTCCAGAGCTCATTGAGCTCCTGACGTCCCAGATTTCCATCCCAACGAGAGATCCCTCGGGACCGTTCCTCATGTCTGTG
GACCACTGTTTCTCCATCAAAGGCCAAGGCACTGTGATGACAGGGACCATCCTTTCAGGCTCCATCAGCCTCGGTGACAGTGTGGAGATC
CCTGCCCTCAAGGTGGTGAAGAAGGTGAAGTCCATGCAGATGTTCCACATGCCCATCACTTCAGCCATGCAAGGAGACCGGCTGGGCATC
TGCGTCACCCAGTTTGACCCTAAGCTGCTGGAGCGCGGGTTGGTGTGTGCCCCCGAGTCCCTGCACACTGTCCATGCGGCCCTCATCTCT
GTGGAAAAGATACCGTATTTCCGGGGGCCCCTGCAAACCAAGGCCAAGTTCCACATTACAGTGGGCCATGAAACAGTCATGGGCCGGTTG
ATGTTCTTCAGTCCTGCTCCAGATAACTTTGACCAGGAGCCTATACTGGACTCTTTCAACTTCTCTCAAGAATACCTTTTCCAGGAGCAG
TACCTGTCCAAGGATTTGACACCAGCAGTGACAGACAATGATGAGGCCGACAAGAAGGCCGGCCAGGCCACAGAGGGCCATTGTCCTCGG
CAGCAGTGGGCCCTGGTGGAGTTTGAGAAGCCCGTCACCTGCCCTCGGCTGTGCCTGGTGATTGGCTCCAGGCTAGATGCGGACATTCAC
ACCAACACGTGCCGGCTAGCCTTCCATGGCATCCTGCTCCACGGGCTAGAGGACAGGAACTACGCCGACAGCTTCCTGCCCAGGCTGAAG
GTGTACAAGCTGAAGCACAAGCATGGCCTTGTGGAGCGGGCGATGGATGACTACAGTGTGATCGGCCGCTCCCTGTTCAAAAAGGAAACC
AACATCCAGCTCTTCGTGGGGCTCAAGGTGCACTTGTCCACTGGGGAACTGGGCATCATCGACAGTGCCTTCGGCCAGAGCGGCAAGTTC
AAGATCCACATCCCAGGTGGCCTCAGCCCCGAGTCCAAGAAGATCCTGACACCCGCCCTCAAGAAGCGGGCCCGGGCTGGCCGTGGGGAG
GCCACCAGGCAGGAGGAGAGCGCCGAGCGGAGCGAGCCCTCACAGCATGTGGTGCTCAGCCTGACTTTCAAGCGTTATGTCTTCGACACC
CACAAGCGCATGGTTCAGTCTCCCTGAGTGTCCGGTGACCTCCCCCAGGGCCTCCTTGCCCAGCCCAGTCCAGGCTGCTGTGCCAAATCC
CAACCAGCCACGCCTCAGCCTCTCCCAGTCTCTCCCTGCAGTCCTGCAGCAGCAGCCCCCACCCCCAAGCTTGGTGCTGAGCCCTGGTGA
GGAGCTGAGGGGGATGGGTTGCTGGGGCCAGGAGGGTCTCTCCTCCAGCCCCTGCACACTCCCACCCAGGACAGCCCCCAGCCCAACTAG
GAAAGGGCCATGGGCAGAGGGCTGGTAGCCAGTATCTTCCACTGCCCCATCTGTTGGCCACCTGCAGGCCAGTCTCAACCCTCCCCCAGG

>In-frame_ENST00000265052_ENST00000254730_TCGA-BR-8058-01A_MGLL_chr3_127500632_-_EEFSEC_chr3_127965679_length(amino acids)=596AA_start in transcript=486_stop in transcript=2276
MVLILQAVVVVECKRQHIMETGPEDPSSMPEESSPRRTPQSIPYQDLPHLVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEELA
RMLMGLDLLVFAHDHGAQIIDLMMLVIDVTKGMQTQSAECLVIGQIACQKLVVVLNKIDLLPEGKRQAAIDKMTKKMQKTLENTKFRGAP
IIPVAAKPGGPEAPETEAPQGIPELIELLTSQISIPTRDPSGPFLMSVDHCFSIKGQGTVMTGTILSGSISLGDSVEIPALKVVKKVKSM
QMFHMPITSAMQGDRLGICVTQFDPKLLERGLVCAPESLHTVHAALISVEKIPYFRGPLQTKAKFHITVGHETVMGRLMFFSPAPDNFDQ
EPILDSFNFSQEYLFQEQYLSKDLTPAVTDNDEADKKAGQATEGHCPRQQWALVEFEKPVTCPRLCLVIGSRLDADIHTNTCRLAFHGIL
LHGLEDRNYADSFLPRLKVYKLKHKHGLVERAMDDYSVIGRSLFKKETNIQLFVGLKVHLSTGELGIIDSAFGQSGKFKIHIPGGLSPES

--------------------------------------------------------------
>In-frame_ENST00000265052_ENST00000483457_TCGA-BR-8058-01A_MGLL_chr3_127500632_-_EEFSEC_chr3_127965679_length(transcript)=2338nt_BP=802nt
CTCCATCTTTCTAGTCCCCACCTTCCCCGGTGCAGACACCCGGCGAAGCCCACCCGGTTTTCCCAGCGGCATTTCCGATGACAGCTTCGG
GGCTACGTGTCCTGTGCTGTCGGAGACGCACAGGAAGCAAAGTTTGTGAGAAGCCTTGGGGGCGACTTTGCCTTGGGCACCCGCATTTGT
GCGTCTGCGAGGTGCCTCGGTGTGCGCGGAGCTAGTTTCCCAGTTTCCCGGGCCCCTCCCTTCTCCGAGCCCCTCTAGCGATTTGTTTAG
GAAAAGTGATGACATGAACTAGTAGTGGAGAATCGCAGCGCCGCTCCCCGCCCTGGGGAGGGAGGGGAGCCCCGGAGAGCCTGCCGGTGG
GAGCTGGAAGCAGGCTCCCGGCTGAGCGCCCCAGCCCGAAAGGCAGGGTCTGGGTGCGGGAAGAGGGCTCGGAGCTGCCTTCCTGCTGCC
TTGGGGCCGCCCAGATGAGGGAACAGCCCGATTTGCCTGGTTCTGATTCTCCAGGCTGTCGTGGTTGTGGAATGCAAACGCCAGCACATA
ATGGAAACAGGACCTGAAGACCCTTCCAGCATGCCAGAGGAAAGTTCCCCCAGGCGGACCCCGCAGAGCATTCCCTACCAGGACCTCCCT
CACCTGGTCAATGCAGACGGACAGTACCTCTTCTGCAGGTACTGGAAACCCACAGGCACACCCAAGGCCCTCATCTTTGTGTCCCATGGA
GCCGGAGAGCACAGTGGCCGCTATGAAGAGCTGGCTCGGATGCTGATGGGGCTGGACCTGCTGGTGTTCGCCCACGACCATGGGGCCCAG
ATCATTGATCTGATGATGCTGGTCATCGATGTGACCAAGGGGATGCAGACCCAGTCAGCGGAATGCCTTGTGATCGGCCAGATTGCCTGC
CAGAAGCTGGTCGTGGTGCTGAACAAAATAGACCTCTTACCTGAAGGAAAGAGACAGGCAGCAATTGATAAAATGACCAAGAAAATGCAG
AAGACCCTAGAGAACACCAAGTTCCGAGGTGCACCGATTATACCCGTGGCGGCCAAGCCGGGGGGACCAGAGGCCCCCGAAACTGAAGCT
CCACAGGGCATTCCAGAGCTCATTGAGGTGGTGAAGAAGGTGAAGTCCATGCAGATGTTCCACATGCCCATCACTTCAGCCATGCAAGGA
GACCGGCTGGGCATCTGCGTCACCCAGTTTGACCCTAAGCTGCTGGAGCGCGGGTTGGTGTGTGCCCCCGAGTCCCTGCACACTGTCCAT
GCGGCCCTCATCTCTGTGGAAAAGATACCGTATTTCCGGGGGCCCCTGCAAACCAAGGCCAAGTTCCACATTACAGTGGGCCATGAAACA
GTCATGGGCCGGTTGATGTTCTTCAGTCCTGCTCCAGATAACTTTGACCAGGAGCCTATACTGGACTCTTTCAACTTCTCTCAAGAATAC
CTTTTCCAGGAGCAGTACCTGTCCAAGGATTTGACACCAGCAGTGACAGACAATGATGAGGCCGACAAGAAGGCCGGCCAGGCCACAGAG
GGCCATTGTCCTCGGCAGCAGTGGGCCCTGGTGGAGTTTGAGAAGCCCGTCACCTGCCCTCGGCTGTGCCTGGTGATTGGCTCCAGGCTA
GATGCGGACATTCACACCAACACGTGCCGGCTAGCCTTCCATGGCATCCTGCTCCACGGGCTAGAGGACAGGAACTACGCCGACAGCTTC
CTGCCCAGGCTGAAGGTGTACAAGCTGAAGCACAAGCATGGCCTTGTGGAGCGGGTGGCCTCAGCCCCGAGTCCAAGAAGATCCTGACAC
CCGCCCTCAAGAAGCGGGCCCGGGCTGGCCGTGGGGAGGCCACCAGGCAGGAGGAGAGCGCCGAGCGGAGCGAGCCCTCACAGCATGTGG
TGCTCAGCCTGACTTTCAAGCGTTATGTCTTCGACACCCACAAGCGCATGGTTCAGTCTCCCTGAGTGTCCGGTGACCTCCCCCAGGGCC
TCCTTGCCCAGCCCAGTCCAGGCTGCTGTGCCAAATCCCAACCAGCCACGCCTCAGCCTCTCCCAGTCTCTCCCTGCAGTCCTGCAGCAG
CAGCCCCCACCCCCAAGCTTGGTGCTGAGCCCTGGTGAGGAGCTGAGGGGGATGGGTTGCTGGGGCCAGGAGGGTCTCTCCTCCAGCCCC
TGCACACTCCCACCCAGGACAGCCCCCAGCCCAACTAGGAAAGGGCCATGGGCAGAGGGCTGGTAGCCAGTATCTTCCACTGCCCCATCT

>In-frame_ENST00000265052_ENST00000483457_TCGA-BR-8058-01A_MGLL_chr3_127500632_-_EEFSEC_chr3_127965679_length(amino acids)=436AA_start in transcript=486_stop in transcript=1796
MVLILQAVVVVECKRQHIMETGPEDPSSMPEESSPRRTPQSIPYQDLPHLVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEELA
RMLMGLDLLVFAHDHGAQIIDLMMLVIDVTKGMQTQSAECLVIGQIACQKLVVVLNKIDLLPEGKRQAAIDKMTKKMQKTLENTKFRGAP
IIPVAAKPGGPEAPETEAPQGIPELIEVVKKVKSMQMFHMPITSAMQGDRLGICVTQFDPKLLERGLVCAPESLHTVHAALISVEKIPYF
RGPLQTKAKFHITVGHETVMGRLMFFSPAPDNFDQEPILDSFNFSQEYLFQEQYLSKDLTPAVTDNDEADKKAGQATEGHCPRQQWALVE

--------------------------------------------------------------
>In-frame_ENST00000398104_ENST00000254730_TCGA-BR-8058-01A_MGLL_chr3_127500632_-_EEFSEC_chr3_127965679_length(transcript)=2235nt_BP=377nt
TGGCGGCGCAGACGCCGCACCCTGTCGCCGCGAAGCCGGTCGCGCGCAGCTCGTCCCGGCCCTGGCCCGCCGCAAACGAGGATCCGCTGC
GCTCGGGGAACGCGACAGCGGCGCTCGTGGCCCCGGACCTGAAGACCCTTCCAGCATGCCAGAGGAAAGTTCCCCCAGGCGGACCCCGCA
GAGCATTCCCTACCAGGACCTCCCTCACCTGGTCAATGCAGACGGACAGTACCTCTTCTGCAGGTACTGGAAACCCACAGGCACACCCAA
GGCCCTCATCTTTGTGTCCCATGGAGCCGGAGAGCACAGTGGCCGCTATGAAGAGCTGGCTCGGATGCTGATGGGGCTGGACCTGCTGGT
GTTCGCCCACGACCATGGGGCCCAGATCATTGATCTGATGATGCTGGTCATCGATGTGACCAAGGGGATGCAGACCCAGTCAGCGGAATG
CCTTGTGATCGGCCAGATTGCCTGCCAGAAGCTGGTCGTGGTGCTGAACAAAATAGACCTCTTACCTGAAGGAAAGAGACAGGCAGCAAT
TGATAAAATGACCAAGAAAATGCAGAAGACCCTAGAGAACACCAAGTTCCGAGGTGCACCGATTATACCCGTGGCGGCCAAGCCGGGGGG
ACCAGAGGCCCCCGAAACTGAAGCTCCACAGGGCATTCCAGAGCTCATTGAGCTCCTGACGTCCCAGATTTCCATCCCAACGAGAGATCC
CTCGGGACCGTTCCTCATGTCTGTGGACCACTGTTTCTCCATCAAAGGCCAAGGCACTGTGATGACAGGGACCATCCTTTCAGGCTCCAT
CAGCCTCGGTGACAGTGTGGAGATCCCTGCCCTCAAGGTGGTGAAGAAGGTGAAGTCCATGCAGATGTTCCACATGCCCATCACTTCAGC
CATGCAAGGAGACCGGCTGGGCATCTGCGTCACCCAGTTTGACCCTAAGCTGCTGGAGCGCGGGTTGGTGTGTGCCCCCGAGTCCCTGCA
CACTGTCCATGCGGCCCTCATCTCTGTGGAAAAGATACCGTATTTCCGGGGGCCCCTGCAAACCAAGGCCAAGTTCCACATTACAGTGGG
CCATGAAACAGTCATGGGCCGGTTGATGTTCTTCAGTCCTGCTCCAGATAACTTTGACCAGGAGCCTATACTGGACTCTTTCAACTTCTC
TCAAGAATACCTTTTCCAGGAGCAGTACCTGTCCAAGGATTTGACACCAGCAGTGACAGACAATGATGAGGCCGACAAGAAGGCCGGCCA
GGCCACAGAGGGCCATTGTCCTCGGCAGCAGTGGGCCCTGGTGGAGTTTGAGAAGCCCGTCACCTGCCCTCGGCTGTGCCTGGTGATTGG
CTCCAGGCTAGATGCGGACATTCACACCAACACGTGCCGGCTAGCCTTCCATGGCATCCTGCTCCACGGGCTAGAGGACAGGAACTACGC
CGACAGCTTCCTGCCCAGGCTGAAGGTGTACAAGCTGAAGCACAAGCATGGCCTTGTGGAGCGGGCGATGGATGACTACAGTGTGATCGG
CCGCTCCCTGTTCAAAAAGGAAACCAACATCCAGCTCTTCGTGGGGCTCAAGGTGCACTTGTCCACTGGGGAACTGGGCATCATCGACAG
TGCCTTCGGCCAGAGCGGCAAGTTCAAGATCCACATCCCAGGTGGCCTCAGCCCCGAGTCCAAGAAGATCCTGACACCCGCCCTCAAGAA
GCGGGCCCGGGCTGGCCGTGGGGAGGCCACCAGGCAGGAGGAGAGCGCCGAGCGGAGCGAGCCCTCACAGCATGTGGTGCTCAGCCTGAC
TTTCAAGCGTTATGTCTTCGACACCCACAAGCGCATGGTTCAGTCTCCCTGAGTGTCCGGTGACCTCCCCCAGGGCCTCCTTGCCCAGCC
CAGTCCAGGCTGCTGTGCCAAATCCCAACCAGCCACGCCTCAGCCTCTCCCAGTCTCTCCCTGCAGTCCTGCAGCAGCAGCCCCCACCCC
CAAGCTTGGTGCTGAGCCCTGGTGAGGAGCTGAGGGGGATGGGTTGCTGGGGCCAGGAGGGTCTCTCCTCCAGCCCCTGCACACTCCCAC
CCAGGACAGCCCCCAGCCCAACTAGGAAAGGGCCATGGGCAGAGGGCTGGTAGCCAGTATCTTCCACTGCCCCATCTGTTGGCCACCTGC

>In-frame_ENST00000398104_ENST00000254730_TCGA-BR-8058-01A_MGLL_chr3_127500632_-_EEFSEC_chr3_127965679_length(amino acids)=596AA_start in transcript=61_stop in transcript=1851
MARRKRGSAALGERDSGARGPGPEDPSSMPEESSPRRTPQSIPYQDLPHLVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEELA
RMLMGLDLLVFAHDHGAQIIDLMMLVIDVTKGMQTQSAECLVIGQIACQKLVVVLNKIDLLPEGKRQAAIDKMTKKMQKTLENTKFRGAP
IIPVAAKPGGPEAPETEAPQGIPELIELLTSQISIPTRDPSGPFLMSVDHCFSIKGQGTVMTGTILSGSISLGDSVEIPALKVVKKVKSM
QMFHMPITSAMQGDRLGICVTQFDPKLLERGLVCAPESLHTVHAALISVEKIPYFRGPLQTKAKFHITVGHETVMGRLMFFSPAPDNFDQ
EPILDSFNFSQEYLFQEQYLSKDLTPAVTDNDEADKKAGQATEGHCPRQQWALVEFEKPVTCPRLCLVIGSRLDADIHTNTCRLAFHGIL
LHGLEDRNYADSFLPRLKVYKLKHKHGLVERAMDDYSVIGRSLFKKETNIQLFVGLKVHLSTGELGIIDSAFGQSGKFKIHIPGGLSPES

--------------------------------------------------------------
>In-frame_ENST00000398104_ENST00000483457_TCGA-BR-8058-01A_MGLL_chr3_127500632_-_EEFSEC_chr3_127965679_length(transcript)=1913nt_BP=377nt
TGGCGGCGCAGACGCCGCACCCTGTCGCCGCGAAGCCGGTCGCGCGCAGCTCGTCCCGGCCCTGGCCCGCCGCAAACGAGGATCCGCTGC
GCTCGGGGAACGCGACAGCGGCGCTCGTGGCCCCGGACCTGAAGACCCTTCCAGCATGCCAGAGGAAAGTTCCCCCAGGCGGACCCCGCA
GAGCATTCCCTACCAGGACCTCCCTCACCTGGTCAATGCAGACGGACAGTACCTCTTCTGCAGGTACTGGAAACCCACAGGCACACCCAA
GGCCCTCATCTTTGTGTCCCATGGAGCCGGAGAGCACAGTGGCCGCTATGAAGAGCTGGCTCGGATGCTGATGGGGCTGGACCTGCTGGT
GTTCGCCCACGACCATGGGGCCCAGATCATTGATCTGATGATGCTGGTCATCGATGTGACCAAGGGGATGCAGACCCAGTCAGCGGAATG
CCTTGTGATCGGCCAGATTGCCTGCCAGAAGCTGGTCGTGGTGCTGAACAAAATAGACCTCTTACCTGAAGGAAAGAGACAGGCAGCAAT
TGATAAAATGACCAAGAAAATGCAGAAGACCCTAGAGAACACCAAGTTCCGAGGTGCACCGATTATACCCGTGGCGGCCAAGCCGGGGGG
ACCAGAGGCCCCCGAAACTGAAGCTCCACAGGGCATTCCAGAGCTCATTGAGGTGGTGAAGAAGGTGAAGTCCATGCAGATGTTCCACAT
GCCCATCACTTCAGCCATGCAAGGAGACCGGCTGGGCATCTGCGTCACCCAGTTTGACCCTAAGCTGCTGGAGCGCGGGTTGGTGTGTGC
CCCCGAGTCCCTGCACACTGTCCATGCGGCCCTCATCTCTGTGGAAAAGATACCGTATTTCCGGGGGCCCCTGCAAACCAAGGCCAAGTT
CCACATTACAGTGGGCCATGAAACAGTCATGGGCCGGTTGATGTTCTTCAGTCCTGCTCCAGATAACTTTGACCAGGAGCCTATACTGGA
CTCTTTCAACTTCTCTCAAGAATACCTTTTCCAGGAGCAGTACCTGTCCAAGGATTTGACACCAGCAGTGACAGACAATGATGAGGCCGA
CAAGAAGGCCGGCCAGGCCACAGAGGGCCATTGTCCTCGGCAGCAGTGGGCCCTGGTGGAGTTTGAGAAGCCCGTCACCTGCCCTCGGCT
GTGCCTGGTGATTGGCTCCAGGCTAGATGCGGACATTCACACCAACACGTGCCGGCTAGCCTTCCATGGCATCCTGCTCCACGGGCTAGA
GGACAGGAACTACGCCGACAGCTTCCTGCCCAGGCTGAAGGTGTACAAGCTGAAGCACAAGCATGGCCTTGTGGAGCGGGTGGCCTCAGC
CCCGAGTCCAAGAAGATCCTGACACCCGCCCTCAAGAAGCGGGCCCGGGCTGGCCGTGGGGAGGCCACCAGGCAGGAGGAGAGCGCCGAG
CGGAGCGAGCCCTCACAGCATGTGGTGCTCAGCCTGACTTTCAAGCGTTATGTCTTCGACACCCACAAGCGCATGGTTCAGTCTCCCTGA
GTGTCCGGTGACCTCCCCCAGGGCCTCCTTGCCCAGCCCAGTCCAGGCTGCTGTGCCAAATCCCAACCAGCCACGCCTCAGCCTCTCCCA
GTCTCTCCCTGCAGTCCTGCAGCAGCAGCCCCCACCCCCAAGCTTGGTGCTGAGCCCTGGTGAGGAGCTGAGGGGGATGGGTTGCTGGGG
CCAGGAGGGTCTCTCCTCCAGCCCCTGCACACTCCCACCCAGGACAGCCCCCAGCCCAACTAGGAAAGGGCCATGGGCAGAGGGCTGGTA
GCCAGTATCTTCCACTGCCCCATCTGTTGGCCACCTGCAGGCCAGTCTCAACCCTCCCCCAGGTGGGCAGGCACTTGATGGCTACAAATA

>In-frame_ENST00000398104_ENST00000483457_TCGA-BR-8058-01A_MGLL_chr3_127500632_-_EEFSEC_chr3_127965679_length(amino acids)=436AA_start in transcript=61_stop in transcript=1371
MARRKRGSAALGERDSGARGPGPEDPSSMPEESSPRRTPQSIPYQDLPHLVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEELA
RMLMGLDLLVFAHDHGAQIIDLMMLVIDVTKGMQTQSAECLVIGQIACQKLVVVLNKIDLLPEGKRQAAIDKMTKKMQKTLENTKFRGAP
IIPVAAKPGGPEAPETEAPQGIPELIEVVKKVKSMQMFHMPITSAMQGDRLGICVTQFDPKLLERGLVCAPESLHTVHAALISVEKIPYF
RGPLQTKAKFHITVGHETVMGRLMFFSPAPDNFDQEPILDSFNFSQEYLFQEQYLSKDLTPAVTDNDEADKKAGQATEGHCPRQQWALVE

--------------------------------------------------------------
>In-frame_ENST00000453507_ENST00000254730_TCGA-BR-8058-01A_MGLL_chr3_127500632_-_EEFSEC_chr3_127965679_length(transcript)=2153nt_BP=295nt
GTCGTGGTTGTGGAATGCAAACGCCAGCACATAATGGAAACAGGACCTGAAGACCCTTCCAGCATGCCAGAGGAAAGTTCCCCCAGGCGG
ACCCCGCAGAGCATTCCCTACCAGGACCTCCCTCACCTGGTCAATGCAGACGGACAGTACCTCTTCTGCAGGTACTGGAAACCCACAGGC
ACACCCAAGGCCCTCATCTTTGTGTCCCATGGAGCCGGAGAGCACAGTGGCCGCTATGAAGAGCTGGCTCGGATGCTGATGGGGCTGGAC
CTGCTGGTGTTCGCCCACGACCATGGGGCCCAGATCATTGATCTGATGATGCTGGTCATCGATGTGACCAAGGGGATGCAGACCCAGTCA
GCGGAATGCCTTGTGATCGGCCAGATTGCCTGCCAGAAGCTGGTCGTGGTGCTGAACAAAATAGACCTCTTACCTGAAGGAAAGAGACAG
GCAGCAATTGATAAAATGACCAAGAAAATGCAGAAGACCCTAGAGAACACCAAGTTCCGAGGTGCACCGATTATACCCGTGGCGGCCAAG
CCGGGGGGACCAGAGGCCCCCGAAACTGAAGCTCCACAGGGCATTCCAGAGCTCATTGAGCTCCTGACGTCCCAGATTTCCATCCCAACG
AGAGATCCCTCGGGACCGTTCCTCATGTCTGTGGACCACTGTTTCTCCATCAAAGGCCAAGGCACTGTGATGACAGGGACCATCCTTTCA
GGCTCCATCAGCCTCGGTGACAGTGTGGAGATCCCTGCCCTCAAGGTGGTGAAGAAGGTGAAGTCCATGCAGATGTTCCACATGCCCATC
ACTTCAGCCATGCAAGGAGACCGGCTGGGCATCTGCGTCACCCAGTTTGACCCTAAGCTGCTGGAGCGCGGGTTGGTGTGTGCCCCCGAG
TCCCTGCACACTGTCCATGCGGCCCTCATCTCTGTGGAAAAGATACCGTATTTCCGGGGGCCCCTGCAAACCAAGGCCAAGTTCCACATT
ACAGTGGGCCATGAAACAGTCATGGGCCGGTTGATGTTCTTCAGTCCTGCTCCAGATAACTTTGACCAGGAGCCTATACTGGACTCTTTC
AACTTCTCTCAAGAATACCTTTTCCAGGAGCAGTACCTGTCCAAGGATTTGACACCAGCAGTGACAGACAATGATGAGGCCGACAAGAAG
GCCGGCCAGGCCACAGAGGGCCATTGTCCTCGGCAGCAGTGGGCCCTGGTGGAGTTTGAGAAGCCCGTCACCTGCCCTCGGCTGTGCCTG
GTGATTGGCTCCAGGCTAGATGCGGACATTCACACCAACACGTGCCGGCTAGCCTTCCATGGCATCCTGCTCCACGGGCTAGAGGACAGG
AACTACGCCGACAGCTTCCTGCCCAGGCTGAAGGTGTACAAGCTGAAGCACAAGCATGGCCTTGTGGAGCGGGCGATGGATGACTACAGT
GTGATCGGCCGCTCCCTGTTCAAAAAGGAAACCAACATCCAGCTCTTCGTGGGGCTCAAGGTGCACTTGTCCACTGGGGAACTGGGCATC
ATCGACAGTGCCTTCGGCCAGAGCGGCAAGTTCAAGATCCACATCCCAGGTGGCCTCAGCCCCGAGTCCAAGAAGATCCTGACACCCGCC
CTCAAGAAGCGGGCCCGGGCTGGCCGTGGGGAGGCCACCAGGCAGGAGGAGAGCGCCGAGCGGAGCGAGCCCTCACAGCATGTGGTGCTC
AGCCTGACTTTCAAGCGTTATGTCTTCGACACCCACAAGCGCATGGTTCAGTCTCCCTGAGTGTCCGGTGACCTCCCCCAGGGCCTCCTT
GCCCAGCCCAGTCCAGGCTGCTGTGCCAAATCCCAACCAGCCACGCCTCAGCCTCTCCCAGTCTCTCCCTGCAGTCCTGCAGCAGCAGCC
CCCACCCCCAAGCTTGGTGCTGAGCCCTGGTGAGGAGCTGAGGGGGATGGGTTGCTGGGGCCAGGAGGGTCTCTCCTCCAGCCCCTGCAC
ACTCCCACCCAGGACAGCCCCCAGCCCAACTAGGAAAGGGCCATGGGCAGAGGGCTGGTAGCCAGTATCTTCCACTGCCCCATCTGTTGG

>In-frame_ENST00000453507_ENST00000254730_TCGA-BR-8058-01A_MGLL_chr3_127500632_-_EEFSEC_chr3_127965679_length(amino acids)=578AA_start in transcript=33_stop in transcript=1769
METGPEDPSSMPEESSPRRTPQSIPYQDLPHLVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHGAQ
IIDLMMLVIDVTKGMQTQSAECLVIGQIACQKLVVVLNKIDLLPEGKRQAAIDKMTKKMQKTLENTKFRGAPIIPVAAKPGGPEAPETEA
PQGIPELIELLTSQISIPTRDPSGPFLMSVDHCFSIKGQGTVMTGTILSGSISLGDSVEIPALKVVKKVKSMQMFHMPITSAMQGDRLGI
CVTQFDPKLLERGLVCAPESLHTVHAALISVEKIPYFRGPLQTKAKFHITVGHETVMGRLMFFSPAPDNFDQEPILDSFNFSQEYLFQEQ
YLSKDLTPAVTDNDEADKKAGQATEGHCPRQQWALVEFEKPVTCPRLCLVIGSRLDADIHTNTCRLAFHGILLHGLEDRNYADSFLPRLK
VYKLKHKHGLVERAMDDYSVIGRSLFKKETNIQLFVGLKVHLSTGELGIIDSAFGQSGKFKIHIPGGLSPESKKILTPALKKRARAGRGE

--------------------------------------------------------------
>In-frame_ENST00000453507_ENST00000483457_TCGA-BR-8058-01A_MGLL_chr3_127500632_-_EEFSEC_chr3_127965679_length(transcript)=1831nt_BP=295nt
GTCGTGGTTGTGGAATGCAAACGCCAGCACATAATGGAAACAGGACCTGAAGACCCTTCCAGCATGCCAGAGGAAAGTTCCCCCAGGCGG
ACCCCGCAGAGCATTCCCTACCAGGACCTCCCTCACCTGGTCAATGCAGACGGACAGTACCTCTTCTGCAGGTACTGGAAACCCACAGGC
ACACCCAAGGCCCTCATCTTTGTGTCCCATGGAGCCGGAGAGCACAGTGGCCGCTATGAAGAGCTGGCTCGGATGCTGATGGGGCTGGAC
CTGCTGGTGTTCGCCCACGACCATGGGGCCCAGATCATTGATCTGATGATGCTGGTCATCGATGTGACCAAGGGGATGCAGACCCAGTCA
GCGGAATGCCTTGTGATCGGCCAGATTGCCTGCCAGAAGCTGGTCGTGGTGCTGAACAAAATAGACCTCTTACCTGAAGGAAAGAGACAG
GCAGCAATTGATAAAATGACCAAGAAAATGCAGAAGACCCTAGAGAACACCAAGTTCCGAGGTGCACCGATTATACCCGTGGCGGCCAAG
CCGGGGGGACCAGAGGCCCCCGAAACTGAAGCTCCACAGGGCATTCCAGAGCTCATTGAGGTGGTGAAGAAGGTGAAGTCCATGCAGATG
TTCCACATGCCCATCACTTCAGCCATGCAAGGAGACCGGCTGGGCATCTGCGTCACCCAGTTTGACCCTAAGCTGCTGGAGCGCGGGTTG
GTGTGTGCCCCCGAGTCCCTGCACACTGTCCATGCGGCCCTCATCTCTGTGGAAAAGATACCGTATTTCCGGGGGCCCCTGCAAACCAAG
GCCAAGTTCCACATTACAGTGGGCCATGAAACAGTCATGGGCCGGTTGATGTTCTTCAGTCCTGCTCCAGATAACTTTGACCAGGAGCCT
ATACTGGACTCTTTCAACTTCTCTCAAGAATACCTTTTCCAGGAGCAGTACCTGTCCAAGGATTTGACACCAGCAGTGACAGACAATGAT
GAGGCCGACAAGAAGGCCGGCCAGGCCACAGAGGGCCATTGTCCTCGGCAGCAGTGGGCCCTGGTGGAGTTTGAGAAGCCCGTCACCTGC
CCTCGGCTGTGCCTGGTGATTGGCTCCAGGCTAGATGCGGACATTCACACCAACACGTGCCGGCTAGCCTTCCATGGCATCCTGCTCCAC
GGGCTAGAGGACAGGAACTACGCCGACAGCTTCCTGCCCAGGCTGAAGGTGTACAAGCTGAAGCACAAGCATGGCCTTGTGGAGCGGGTG
GCCTCAGCCCCGAGTCCAAGAAGATCCTGACACCCGCCCTCAAGAAGCGGGCCCGGGCTGGCCGTGGGGAGGCCACCAGGCAGGAGGAGA
GCGCCGAGCGGAGCGAGCCCTCACAGCATGTGGTGCTCAGCCTGACTTTCAAGCGTTATGTCTTCGACACCCACAAGCGCATGGTTCAGT
CTCCCTGAGTGTCCGGTGACCTCCCCCAGGGCCTCCTTGCCCAGCCCAGTCCAGGCTGCTGTGCCAAATCCCAACCAGCCACGCCTCAGC
CTCTCCCAGTCTCTCCCTGCAGTCCTGCAGCAGCAGCCCCCACCCCCAAGCTTGGTGCTGAGCCCTGGTGAGGAGCTGAGGGGGATGGGT
TGCTGGGGCCAGGAGGGTCTCTCCTCCAGCCCCTGCACACTCCCACCCAGGACAGCCCCCAGCCCAACTAGGAAAGGGCCATGGGCAGAG
GGCTGGTAGCCAGTATCTTCCACTGCCCCATCTGTTGGCCACCTGCAGGCCAGTCTCAACCCTCCCCCAGGTGGGCAGGCACTTGATGGC

>In-frame_ENST00000453507_ENST00000483457_TCGA-BR-8058-01A_MGLL_chr3_127500632_-_EEFSEC_chr3_127965679_length(amino acids)=418AA_start in transcript=33_stop in transcript=1289
METGPEDPSSMPEESSPRRTPQSIPYQDLPHLVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHGAQ
IIDLMMLVIDVTKGMQTQSAECLVIGQIACQKLVVVLNKIDLLPEGKRQAAIDKMTKKMQKTLENTKFRGAPIIPVAAKPGGPEAPETEA
PQGIPELIEVVKKVKSMQMFHMPITSAMQGDRLGICVTQFDPKLLERGLVCAPESLHTVHAALISVEKIPYFRGPLQTKAKFHITVGHET
VMGRLMFFSPAPDNFDQEPILDSFNFSQEYLFQEQYLSKDLTPAVTDNDEADKKAGQATEGHCPRQQWALVEFEKPVTCPRLCLVIGSRL

--------------------------------------------------------------

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Fusion Gene PPI Analysis for MGLL-EEFSEC


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for MGLL-EEFSEC


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for MGLL-EEFSEC


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneMGLLC0001787Osteoporosis, Age-Related1CTD_human
HgeneMGLLC0029456Osteoporosis1CTD_human
HgeneMGLLC0029459Osteoporosis, Senile1CTD_human
HgeneMGLLC0751406Post-Traumatic Osteoporosis1CTD_human
TgeneEEFSECC0024117Chronic Obstructive Airway Disease1CTD_human
TgeneEEFSECC1527303Chronic Airflow Obstruction1CTD_human