Home

Download

Statistics

Examples

Help

Contact

	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:MGST1-TUBB (FusionGDB2 ID:53129)

Fusion Gene Summary for MGST1-TUBB

Fusion gene summary

Fusion gene information	Fusion gene name: MGST1-TUBB
	Fusion gene ID: 53129
		Hgene	Tgene
	Gene symbol	MGST1	TUBB
	Gene ID	4257	203068
	Gene name	microsomal glutathione S-transferase 1	tubulin beta class I
	Synonyms	GST12\|MGST\|MGST-I	CDCBM6\|CSCSC1\|M40\|OK/SW-cl.56\|TUBB1\|TUBB5
	Cytomap	12p12.3	6p21.33
	Type of gene	protein-coding	protein-coding
	Description	microsomal glutathione S-transferase 1glutathione S-transferase 12microsomal GST-1microsomal GST-I	tubulin beta chainbeta Ib tubulinepididymis secretory sperm binding proteintubulin beta-1 chaintubulin beta-5 chaintubulin, beta polypeptide
	Modification date	20200320	20200327
	UniProtAcc	P10620	TULP4
	Ensembl transtripts involved in fusion gene	ENST00000010404, ENST00000396210, ENST00000535309, ENST00000540056, ENST00000396209, ENST00000396207, ENST00000359720,	ENST00000327892, ENST00000435534, ENST00000330914, ENST00000396389, ENST00000396384, ENST00000421473, ENST00000549614, ENST00000413547, ENST00000419551, ENST00000454620, ENST00000422674, ENST00000548023, ENST00000435546, ENST00000420400, ENST00000453350, ENST00000419792, ENST00000547690, ENST00000436335, ENST00000425136, ENST00000444441, ENST00000422650, ENST00000547695, ENST00000454454, ENST00000412136, ENST00000446385, ENST00000383564, ENST00000551208, ENST00000400531, ENST00000400534, ENST00000400530, ENST00000436628, ENST00000549902, ENST00000437490, ENST00000426754, ENST00000425102, ENST00000432462, ENST00000549654, ENST00000427480, ENST00000424734, ENST00000420618,
Fusion gene scores	* DoF score	13 X 8 X 6=624	12 X 12 X 3=432
	# samples	13	12
	** MAII score	log2(13/624*10)=-2.26303440583379 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(12/432*10)=-1.84799690655495 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: MGST1 [Title/Abstract] AND TUBB [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	MGST1(16507204)-TUBB(30691716), # samples:1
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	MGST1	GO:0055114	oxidation-reduction process	20727966
Hgene	MGST1	GO:0071449	cellular response to lipid hydroperoxide	20727966
Tgene	TUBB	GO:0009987	cellular process	19567321

Fusion gene breakpoints across MGST1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across TUBB (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	STAD	TCGA-BR-A4QI-01A	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+

Top

Fusion Gene ORF analysis for MGST1-TUBB

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
In-frame	ENST00000010404	ENST00000327892	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000010404	ENST00000435534	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000010404	ENST00000330914	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000010404	ENST00000396389	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000010404	ENST00000396384	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000010404	ENST00000421473	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000010404	ENST00000549614	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000010404	ENST00000413547	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000010404	ENST00000419551	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000010404	ENST00000454620	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000010404	ENST00000422674	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000010404	ENST00000548023	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000010404	ENST00000435546	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000010404	ENST00000420400	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000010404	ENST00000453350	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000010404	ENST00000419792	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000010404	ENST00000547690	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000010404	ENST00000436335	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000010404	ENST00000425136	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000010404	ENST00000444441	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000010404	ENST00000422650	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000010404	ENST00000547695	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000010404	ENST00000454454	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000010404	ENST00000412136	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000010404	ENST00000446385	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000010404	ENST00000383564	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000010404	ENST00000551208	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000010404	ENST00000400531	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000010404	ENST00000400534	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000010404	ENST00000400530	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000010404	ENST00000436628	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000010404	ENST00000549902	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000010404	ENST00000437490	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000010404	ENST00000426754	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000010404	ENST00000425102	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000010404	ENST00000432462	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000010404	ENST00000549654	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000010404	ENST00000427480	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000010404	ENST00000424734	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000010404	ENST00000420618	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
In-frame	ENST00000396210	ENST00000327892	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396210	ENST00000435534	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396210	ENST00000330914	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396210	ENST00000396389	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396210	ENST00000396384	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396210	ENST00000421473	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396210	ENST00000549614	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396210	ENST00000413547	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396210	ENST00000419551	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396210	ENST00000454620	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396210	ENST00000422674	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396210	ENST00000548023	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396210	ENST00000435546	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396210	ENST00000420400	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396210	ENST00000453350	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396210	ENST00000419792	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396210	ENST00000547690	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396210	ENST00000436335	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396210	ENST00000425136	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396210	ENST00000444441	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396210	ENST00000422650	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396210	ENST00000547695	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396210	ENST00000454454	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396210	ENST00000412136	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396210	ENST00000446385	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396210	ENST00000383564	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396210	ENST00000551208	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396210	ENST00000400531	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396210	ENST00000400534	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396210	ENST00000400530	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396210	ENST00000436628	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396210	ENST00000549902	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396210	ENST00000437490	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396210	ENST00000426754	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396210	ENST00000425102	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396210	ENST00000432462	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396210	ENST00000549654	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396210	ENST00000427480	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396210	ENST00000424734	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396210	ENST00000420618	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
In-frame	ENST00000535309	ENST00000327892	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000535309	ENST00000435534	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000535309	ENST00000330914	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000535309	ENST00000396389	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000535309	ENST00000396384	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000535309	ENST00000421473	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000535309	ENST00000549614	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000535309	ENST00000413547	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000535309	ENST00000419551	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000535309	ENST00000454620	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000535309	ENST00000422674	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000535309	ENST00000548023	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000535309	ENST00000435546	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000535309	ENST00000420400	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000535309	ENST00000453350	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000535309	ENST00000419792	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000535309	ENST00000547690	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000535309	ENST00000436335	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000535309	ENST00000425136	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000535309	ENST00000444441	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000535309	ENST00000422650	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000535309	ENST00000547695	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000535309	ENST00000454454	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000535309	ENST00000412136	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000535309	ENST00000446385	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000535309	ENST00000383564	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000535309	ENST00000551208	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000535309	ENST00000400531	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000535309	ENST00000400534	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000535309	ENST00000400530	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000535309	ENST00000436628	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000535309	ENST00000549902	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000535309	ENST00000437490	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000535309	ENST00000426754	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000535309	ENST00000425102	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000535309	ENST00000432462	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000535309	ENST00000549654	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000535309	ENST00000427480	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000535309	ENST00000424734	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000535309	ENST00000420618	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
In-frame	ENST00000540056	ENST00000327892	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000540056	ENST00000435534	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000540056	ENST00000330914	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000540056	ENST00000396389	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000540056	ENST00000396384	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000540056	ENST00000421473	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000540056	ENST00000549614	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000540056	ENST00000413547	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000540056	ENST00000419551	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000540056	ENST00000454620	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000540056	ENST00000422674	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000540056	ENST00000548023	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000540056	ENST00000435546	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000540056	ENST00000420400	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000540056	ENST00000453350	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000540056	ENST00000419792	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000540056	ENST00000547690	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000540056	ENST00000436335	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000540056	ENST00000425136	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000540056	ENST00000444441	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000540056	ENST00000422650	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000540056	ENST00000547695	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000540056	ENST00000454454	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000540056	ENST00000412136	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000540056	ENST00000446385	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000540056	ENST00000383564	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000540056	ENST00000551208	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000540056	ENST00000400531	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000540056	ENST00000400534	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000540056	ENST00000400530	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000540056	ENST00000436628	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000540056	ENST00000549902	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000540056	ENST00000437490	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000540056	ENST00000426754	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000540056	ENST00000425102	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000540056	ENST00000432462	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000540056	ENST00000549654	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000540056	ENST00000427480	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000540056	ENST00000424734	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000540056	ENST00000420618	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
In-frame	ENST00000396209	ENST00000327892	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396209	ENST00000435534	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396209	ENST00000330914	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396209	ENST00000396389	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396209	ENST00000396384	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396209	ENST00000421473	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396209	ENST00000549614	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396209	ENST00000413547	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396209	ENST00000419551	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396209	ENST00000454620	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396209	ENST00000422674	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396209	ENST00000548023	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396209	ENST00000435546	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396209	ENST00000420400	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396209	ENST00000453350	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396209	ENST00000419792	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396209	ENST00000547690	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396209	ENST00000436335	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396209	ENST00000425136	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396209	ENST00000444441	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396209	ENST00000422650	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396209	ENST00000547695	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396209	ENST00000454454	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396209	ENST00000412136	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396209	ENST00000446385	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396209	ENST00000383564	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396209	ENST00000551208	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396209	ENST00000400531	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396209	ENST00000400534	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396209	ENST00000400530	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396209	ENST00000436628	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396209	ENST00000549902	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396209	ENST00000437490	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396209	ENST00000426754	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396209	ENST00000425102	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396209	ENST00000432462	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396209	ENST00000549654	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396209	ENST00000427480	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396209	ENST00000424734	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396209	ENST00000420618	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
In-frame	ENST00000396207	ENST00000327892	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396207	ENST00000435534	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396207	ENST00000330914	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396207	ENST00000396389	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396207	ENST00000396384	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396207	ENST00000421473	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396207	ENST00000549614	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396207	ENST00000413547	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396207	ENST00000419551	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396207	ENST00000454620	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396207	ENST00000422674	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396207	ENST00000548023	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396207	ENST00000435546	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396207	ENST00000420400	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396207	ENST00000453350	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396207	ENST00000419792	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396207	ENST00000547690	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396207	ENST00000436335	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396207	ENST00000425136	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396207	ENST00000444441	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396207	ENST00000422650	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396207	ENST00000547695	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396207	ENST00000454454	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396207	ENST00000412136	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396207	ENST00000446385	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396207	ENST00000383564	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396207	ENST00000551208	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396207	ENST00000400531	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396207	ENST00000400534	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396207	ENST00000400530	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396207	ENST00000436628	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396207	ENST00000549902	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396207	ENST00000437490	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396207	ENST00000426754	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396207	ENST00000425102	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396207	ENST00000432462	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396207	ENST00000549654	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396207	ENST00000427480	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396207	ENST00000424734	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
5CDS-intron	ENST00000396207	ENST00000420618	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
intron-3CDS	ENST00000359720	ENST00000327892	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
intron-intron	ENST00000359720	ENST00000435534	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
intron-intron	ENST00000359720	ENST00000330914	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
intron-intron	ENST00000359720	ENST00000396389	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
intron-intron	ENST00000359720	ENST00000396384	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
intron-intron	ENST00000359720	ENST00000421473	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
intron-intron	ENST00000359720	ENST00000549614	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
intron-intron	ENST00000359720	ENST00000413547	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
intron-intron	ENST00000359720	ENST00000419551	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
intron-intron	ENST00000359720	ENST00000454620	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
intron-intron	ENST00000359720	ENST00000422674	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
intron-intron	ENST00000359720	ENST00000548023	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
intron-intron	ENST00000359720	ENST00000435546	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
intron-intron	ENST00000359720	ENST00000420400	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
intron-intron	ENST00000359720	ENST00000453350	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
intron-intron	ENST00000359720	ENST00000419792	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
intron-intron	ENST00000359720	ENST00000547690	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
intron-intron	ENST00000359720	ENST00000436335	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
intron-intron	ENST00000359720	ENST00000425136	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
intron-intron	ENST00000359720	ENST00000444441	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
intron-intron	ENST00000359720	ENST00000422650	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
intron-intron	ENST00000359720	ENST00000547695	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
intron-intron	ENST00000359720	ENST00000454454	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
intron-intron	ENST00000359720	ENST00000412136	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
intron-intron	ENST00000359720	ENST00000446385	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
intron-intron	ENST00000359720	ENST00000383564	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
intron-intron	ENST00000359720	ENST00000551208	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
intron-intron	ENST00000359720	ENST00000400531	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
intron-intron	ENST00000359720	ENST00000400534	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
intron-intron	ENST00000359720	ENST00000400530	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
intron-intron	ENST00000359720	ENST00000436628	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
intron-intron	ENST00000359720	ENST00000549902	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
intron-intron	ENST00000359720	ENST00000437490	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
intron-intron	ENST00000359720	ENST00000426754	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
intron-intron	ENST00000359720	ENST00000425102	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
intron-intron	ENST00000359720	ENST00000432462	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
intron-intron	ENST00000359720	ENST00000549654	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
intron-intron	ENST00000359720	ENST00000427480	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
intron-intron	ENST00000359720	ENST00000424734	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+
intron-intron	ENST00000359720	ENST00000420618	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000010404	MGST1	chr12	16507204	+	ENST00000327892	TUBB	chr6	30691716	+	1638	151	168	608	146
ENST00000396210	MGST1	chr12	16507204	+	ENST00000327892	TUBB	chr6	30691716	+	1657	170	187	627	146
ENST00000535309	MGST1	chr12	16507204	+	ENST00000327892	TUBB	chr6	30691716	+	1612	125	142	582	146
ENST00000540056	MGST1	chr12	16507204	+	ENST00000327892	TUBB	chr6	30691716	+	1716	229	246	686	146
ENST00000396209	MGST1	chr12	16507204	+	ENST00000327892	TUBB	chr6	30691716	+	1716	229	246	686	146
ENST00000396207	MGST1	chr12	16507204	+	ENST00000327892	TUBB	chr6	30691716	+	1646	159	176	616	146

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000010404	ENST00000327892	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+	0.002586082	0.9974139
ENST00000396210	ENST00000327892	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+	0.002496846	0.9975032
ENST00000535309	ENST00000327892	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+	0.002471751	0.99752825
ENST00000540056	ENST00000327892	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+	0.002027045	0.9979729
ENST00000396209	ENST00000327892	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+	0.002027045	0.9979729
ENST00000396207	ENST00000327892	MGST1	chr12	16507204	+	TUBB	chr6	30691716	+	0.00414219	0.9958578

Top

Fusion Genomic Features for MGST1-TUBB

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

Top

Fusion Protein Features for MGST1-TUBB

Go to
FGviewer for the breakpoints of chr12:16507204-chr6:30691716
.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
MGST1 P10620	TUBB TULP4
FUNCTION: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has a wide substrate specificity.	1543

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Tgene

TUBB

chr12:16507204

chr6:30691716

ENST00000327892

140_146

445.0

Nucleotide binding

GTP

Tgene

TUBB

chr12:16507204

chr6:30691716

ENST00000383564

140_146

445.0

Nucleotide binding

GTP

Tgene

TUBB

chr12:16507204

chr6:30691716

ENST00000419792

140_146

445.0

Nucleotide binding

GTP

Tgene

TUBB

chr12:16507204

chr6:30691716

ENST00000421473

140_146

445.0

Nucleotide binding

GTP

Tgene

TUBB

chr12:16507204

chr6:30691716

ENST00000422650

140_146

445.0

Nucleotide binding

GTP

Tgene

TUBB

chr12:16507204

chr6:30691716

ENST00000422674

140_146

445.0

Nucleotide binding

GTP

Tgene

TUBB

chr12:16507204

chr6:30691716

ENST00000432462

140_146

445.0

Nucleotide binding

GTP

Tgene

TUBB

chr12:16507204

chr6:30691716

ENST00000436628

140_146

445.0

Nucleotide binding

GTP

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

MGST1

chr12:16507204

chr6:30691716

ENST00000010404

124_128

156.0

Topological domain

Cytoplasmic

Hgene

MGST1

chr12:16507204

chr6:30691716

ENST00000010404

149_155

156.0

Topological domain

Lumenal

Hgene

MGST1

chr12:16507204

chr6:30691716

ENST00000010404

34_62

156.0

Topological domain

Cytoplasmic

Hgene

MGST1

chr12:16507204

chr6:30691716

ENST00000010404

3_9

156.0

Topological domain

Lumenal

Hgene

MGST1

chr12:16507204

chr6:30691716

ENST00000010404

97_99

156.0

Topological domain

Lumenal

Hgene

MGST1

chr12:16507204

chr6:30691716

ENST00000396207

124_128

156.0

Topological domain

Cytoplasmic

Hgene

MGST1

chr12:16507204

chr6:30691716

ENST00000396207

149_155

156.0

Topological domain

Lumenal

Hgene

MGST1

chr12:16507204

chr6:30691716

ENST00000396207

34_62

156.0

Topological domain

Cytoplasmic

Hgene

MGST1

chr12:16507204

chr6:30691716

ENST00000396207

3_9

156.0

Topological domain

Lumenal

Hgene

MGST1

chr12:16507204

chr6:30691716

ENST00000396207

97_99

156.0

Topological domain

Lumenal

Hgene

MGST1

chr12:16507204

chr6:30691716

ENST00000396209

124_128

156.0

Topological domain

Cytoplasmic

Hgene

MGST1

chr12:16507204

chr6:30691716

ENST00000396209

149_155

156.0

Topological domain

Lumenal

Hgene

MGST1

chr12:16507204

chr6:30691716

ENST00000396209

34_62

156.0

Topological domain

Cytoplasmic

Hgene

MGST1

chr12:16507204

chr6:30691716

ENST00000396209

3_9

156.0

Topological domain

Lumenal

Hgene

MGST1

chr12:16507204

chr6:30691716

ENST00000396209

97_99

156.0

Topological domain

Lumenal

Hgene

MGST1

chr12:16507204

chr6:30691716

ENST00000396210

124_128

156.0

Topological domain

Cytoplasmic

Hgene

MGST1

chr12:16507204

chr6:30691716

ENST00000396210

149_155

156.0

Topological domain

Lumenal

Hgene

MGST1

chr12:16507204

chr6:30691716

ENST00000396210

34_62

156.0

Topological domain

Cytoplasmic

Hgene

MGST1

chr12:16507204

chr6:30691716

ENST00000396210

3_9

156.0

Topological domain

Lumenal

Hgene

MGST1

chr12:16507204

chr6:30691716

ENST00000396210

97_99

156.0

Topological domain

Lumenal

Hgene

MGST1

chr12:16507204

chr6:30691716

ENST00000535309

124_128

88.0

Topological domain

Cytoplasmic

Hgene

MGST1

chr12:16507204

chr6:30691716

ENST00000535309

149_155

88.0

Topological domain

Lumenal

Hgene

MGST1

chr12:16507204

chr6:30691716

ENST00000535309

34_62

88.0

Topological domain

Cytoplasmic

Hgene

MGST1

chr12:16507204

chr6:30691716

ENST00000535309

3_9

88.0

Topological domain

Lumenal

Hgene

MGST1

chr12:16507204

chr6:30691716

ENST00000535309

97_99

88.0

Topological domain

Lumenal

Hgene

MGST1

chr12:16507204

chr6:30691716

ENST00000010404

100_123

156.0

Transmembrane

Helical

Hgene

MGST1

chr12:16507204

chr6:30691716

ENST00000010404

10_33

156.0

Transmembrane

Helical

Hgene

MGST1

chr12:16507204

chr6:30691716

ENST00000010404

129_148

156.0

Transmembrane

Helical

Hgene

MGST1

chr12:16507204

chr6:30691716

ENST00000010404

63_96

156.0

Transmembrane

Helical

Hgene

MGST1

chr12:16507204

chr6:30691716

ENST00000396207

100_123

156.0

Transmembrane

Helical

Hgene

MGST1

chr12:16507204

chr6:30691716

ENST00000396207

10_33

156.0

Transmembrane

Helical

Hgene

MGST1

chr12:16507204

chr6:30691716

ENST00000396207

129_148

156.0

Transmembrane

Helical

Hgene

MGST1

chr12:16507204

chr6:30691716

ENST00000396207

63_96

156.0

Transmembrane

Helical

Hgene

MGST1

chr12:16507204

chr6:30691716

ENST00000396209

100_123

156.0

Transmembrane

Helical

Hgene

MGST1

chr12:16507204

chr6:30691716

ENST00000396209

10_33

156.0

Transmembrane

Helical

Hgene

MGST1

chr12:16507204

chr6:30691716

ENST00000396209

129_148

156.0

Transmembrane

Helical

Hgene

MGST1

chr12:16507204

chr6:30691716

ENST00000396209

63_96

156.0

Transmembrane

Helical

Hgene

MGST1

chr12:16507204

chr6:30691716

ENST00000396210

100_123

156.0

Transmembrane

Helical

Hgene

MGST1

chr12:16507204

chr6:30691716

ENST00000396210

10_33

156.0

Transmembrane

Helical

Hgene

MGST1

chr12:16507204

chr6:30691716

ENST00000396210

129_148

156.0

Transmembrane

Helical

Hgene

MGST1

chr12:16507204

chr6:30691716

ENST00000396210

63_96

156.0

Transmembrane

Helical

Hgene

MGST1

chr12:16507204

chr6:30691716

ENST00000535309

100_123

88.0

Transmembrane

Helical

Hgene

MGST1

chr12:16507204

chr6:30691716

ENST00000535309

10_33

88.0

Transmembrane

Helical

Hgene

MGST1

chr12:16507204

chr6:30691716

ENST00000535309

129_148

88.0

Transmembrane

Helical

Hgene

MGST1

chr12:16507204

chr6:30691716

ENST00000535309

63_96

88.0

Transmembrane

Helical

Top

Fusion Gene Sequence for MGST1-TUBB

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>In-frame_ENST00000010404_ENST00000327892_TCGA-BR-A4QI-01A_MGST1_chr12_16507204_+_TUBB_chr6_30691716_length(transcript)=1638nt_BP=151nt
TCGTGACAAAGCAAATTGTCTGGTATCATGAATTTGGAACACCGTAATGGATGATGAAGTATTCATGGCTTTTGCATCCTATGCAACAAT
TATTCTTTCAAAAATGATGCTTATGAGTACTGCAACTGCATTCTATAGATTGACAAGAAAGTCTTCGATGCCAAGAACATGATGGCTGCC
TGTGACCCCCGCCACGGCCGATACCTCACCGTGGCTGCTGTCTTCCGTGGTCGGATGTCCATGAAGGAGGTCGATGAGCAGATGCTTAAC
GTGCAGAACAAGAACAGCAGCTACTTTGTGGAATGGATCCCCAACAATGTCAAGACAGCCGTCTGTGACATCCCACCTCGTGGCCTCAAG
ATGGCAGTCACCTTCATTGGCAATAGCACAGCCATCCAGGAGCTCTTCAAGCGCATCTCGGAGCAGTTCACTGCCATGTTCCGCCGGAAG
GCCTTCCTCCACTGGTACACAGGCGAGGGCATGGACGAGATGGAGTTCACCGAGGCTGAGAGCAACATGAACGACCTCGTCTCTGAGTAT
CAGCAGTACCAGGATGCCACCGCAGAAGAGGAGGAGGATTTCGGTGAGGAGGCCGAAGAGGAGGCCTAAGGCAGAGCCCCCATCACCTCA
GGCTTCTCAGTTCCCTTAGCCGTCTTACTCAACTGCCCCTTTCCTCTCCCTCAGAATTTGTGTTTGCTGCCTCTATCTTGTTTTTTGTTT
TTTCTTCTGGGGGGGGTCTAGAACAGTGCCTGGCACATAGTAGGCGCTCAATAAATACTTGTTTGTTGAATGTCTCCTCTCTCTTTCCAC
TCTGGGAAACCTAGGTTTCTGCCATTCTGGGTGACCCTGTATTTCTTTCTGGTGCCCATTCCATTTGTCCAGTTAATACTTCCTCTTAAA
AATCTCCAAGAAGCTGGGTCTCCAGATCCCATTTAGAACCAACCAGGTGCTGAAAACACATGTAGATAATGGCCATCATCCTAAGCCCAA
AGTAGAAAATGGTAGAAGGTAGTGGGTAGAAGTCACTATATAAGGAAGGGGATGGGATTTTCCATTCTAAAAGTTTTGGAGAGGGAAATC
CAGGCTATTAAAGTCACTAAATTTCTAAGTATGTCCATTTCCCATCTCAGCTTCAAGGGAGGTGTCAGCAGTATTATCTCCACTTTCAAT
CTCCCTCCAAGCTCTACTCTGGAGGAGTCTGTCCCACTCTGTCAAGTGGAATCCTTCCCTTTCCAACTCTACCTCCCTCACTCAGCTCCT
TTCCCCTGATCAGAGAAAGGGATCAAGGGGGTTGGGAGGGGGGAAAGAGACCAGCCTTGGTCCCTAAGCCTCCAGAAACGTCTTCTTAAT
CCCCACCTTTTCTTACTCCCAAAAAAGAATGAACACCCCTGACTCTGGAGTGGTGTATACTGCCACATCAGTGTTTGAGTCAGTCCCCAG
AGGAGAGGGGAACCCTCCTCCATCTTTTTTGCAACATCTCATTTCTTCCTTTTGCTGTTGCTTCCCCCCTCACACACTTGGTTTTGTTCT
ATCCTACATTTGAGATTTCTATTTTATGTTGAACTTGCTGCTTTTTTTCATATTGAAAAGATGACATCGCCCCAAGAGCCAAAAATAAAT

>In-frame_ENST00000010404_ENST00000327892_TCGA-BR-A4QI-01A_MGST1_chr12_16507204_+_TUBB_chr6_30691716_length(amino acids)=146AA_start in transcript=168_stop in transcript=608
MMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMAVTFIGNSTAIQELFKRISEQFTAM

--------------------------------------------------------------
>In-frame_ENST00000396210_ENST00000327892_TCGA-BR-A4QI-01A_MGST1_chr12_16507204_+_TUBB_chr6_30691716_length(transcript)=1657nt_BP=170nt
CCTGCATTGCGCGCGACCCGGCGGCGGGACAGGCTTGCTGCTTCCTCCTCCTCGGCCTCACCGTAATGGATGATGAAGTATTCATGGCTT
TTGCATCCTATGCAACAATTATTCTTTCAAAAATGATGCTTATGAGTACTGCAACTGCATTCTATAGATTGACAAGAAAGTCTTCGATGC
CAAGAACATGATGGCTGCCTGTGACCCCCGCCACGGCCGATACCTCACCGTGGCTGCTGTCTTCCGTGGTCGGATGTCCATGAAGGAGGT
CGATGAGCAGATGCTTAACGTGCAGAACAAGAACAGCAGCTACTTTGTGGAATGGATCCCCAACAATGTCAAGACAGCCGTCTGTGACAT
CCCACCTCGTGGCCTCAAGATGGCAGTCACCTTCATTGGCAATAGCACAGCCATCCAGGAGCTCTTCAAGCGCATCTCGGAGCAGTTCAC
TGCCATGTTCCGCCGGAAGGCCTTCCTCCACTGGTACACAGGCGAGGGCATGGACGAGATGGAGTTCACCGAGGCTGAGAGCAACATGAA
CGACCTCGTCTCTGAGTATCAGCAGTACCAGGATGCCACCGCAGAAGAGGAGGAGGATTTCGGTGAGGAGGCCGAAGAGGAGGCCTAAGG
CAGAGCCCCCATCACCTCAGGCTTCTCAGTTCCCTTAGCCGTCTTACTCAACTGCCCCTTTCCTCTCCCTCAGAATTTGTGTTTGCTGCC
TCTATCTTGTTTTTTGTTTTTTCTTCTGGGGGGGGTCTAGAACAGTGCCTGGCACATAGTAGGCGCTCAATAAATACTTGTTTGTTGAAT
GTCTCCTCTCTCTTTCCACTCTGGGAAACCTAGGTTTCTGCCATTCTGGGTGACCCTGTATTTCTTTCTGGTGCCCATTCCATTTGTCCA
GTTAATACTTCCTCTTAAAAATCTCCAAGAAGCTGGGTCTCCAGATCCCATTTAGAACCAACCAGGTGCTGAAAACACATGTAGATAATG
GCCATCATCCTAAGCCCAAAGTAGAAAATGGTAGAAGGTAGTGGGTAGAAGTCACTATATAAGGAAGGGGATGGGATTTTCCATTCTAAA
AGTTTTGGAGAGGGAAATCCAGGCTATTAAAGTCACTAAATTTCTAAGTATGTCCATTTCCCATCTCAGCTTCAAGGGAGGTGTCAGCAG
TATTATCTCCACTTTCAATCTCCCTCCAAGCTCTACTCTGGAGGAGTCTGTCCCACTCTGTCAAGTGGAATCCTTCCCTTTCCAACTCTA
CCTCCCTCACTCAGCTCCTTTCCCCTGATCAGAGAAAGGGATCAAGGGGGTTGGGAGGGGGGAAAGAGACCAGCCTTGGTCCCTAAGCCT
CCAGAAACGTCTTCTTAATCCCCACCTTTTCTTACTCCCAAAAAAGAATGAACACCCCTGACTCTGGAGTGGTGTATACTGCCACATCAG
TGTTTGAGTCAGTCCCCAGAGGAGAGGGGAACCCTCCTCCATCTTTTTTGCAACATCTCATTTCTTCCTTTTGCTGTTGCTTCCCCCCTC
ACACACTTGGTTTTGTTCTATCCTACATTTGAGATTTCTATTTTATGTTGAACTTGCTGCTTTTTTTCATATTGAAAAGATGACATCGCC

>In-frame_ENST00000396210_ENST00000327892_TCGA-BR-A4QI-01A_MGST1_chr12_16507204_+_TUBB_chr6_30691716_length(amino acids)=146AA_start in transcript=187_stop in transcript=627
MMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMAVTFIGNSTAIQELFKRISEQFTAM

--------------------------------------------------------------
>In-frame_ENST00000535309_ENST00000327892_TCGA-BR-A4QI-01A_MGST1_chr12_16507204_+_TUBB_chr6_30691716_length(transcript)=1612nt_BP=125nt
TCCTCCTCGGCCTCACCGTAATGGATGATGAAGTATTCATGGCTTTTGCATCCTATGCAACAATTATTCTTTCAAAAATGATGCTTATGA
GTACTGCAACTGCATTCTATAGATTGACAAGAAAGTCTTCGATGCCAAGAACATGATGGCTGCCTGTGACCCCCGCCACGGCCGATACCT
CACCGTGGCTGCTGTCTTCCGTGGTCGGATGTCCATGAAGGAGGTCGATGAGCAGATGCTTAACGTGCAGAACAAGAACAGCAGCTACTT
TGTGGAATGGATCCCCAACAATGTCAAGACAGCCGTCTGTGACATCCCACCTCGTGGCCTCAAGATGGCAGTCACCTTCATTGGCAATAG
CACAGCCATCCAGGAGCTCTTCAAGCGCATCTCGGAGCAGTTCACTGCCATGTTCCGCCGGAAGGCCTTCCTCCACTGGTACACAGGCGA
GGGCATGGACGAGATGGAGTTCACCGAGGCTGAGAGCAACATGAACGACCTCGTCTCTGAGTATCAGCAGTACCAGGATGCCACCGCAGA
AGAGGAGGAGGATTTCGGTGAGGAGGCCGAAGAGGAGGCCTAAGGCAGAGCCCCCATCACCTCAGGCTTCTCAGTTCCCTTAGCCGTCTT
ACTCAACTGCCCCTTTCCTCTCCCTCAGAATTTGTGTTTGCTGCCTCTATCTTGTTTTTTGTTTTTTCTTCTGGGGGGGGTCTAGAACAG
TGCCTGGCACATAGTAGGCGCTCAATAAATACTTGTTTGTTGAATGTCTCCTCTCTCTTTCCACTCTGGGAAACCTAGGTTTCTGCCATT
CTGGGTGACCCTGTATTTCTTTCTGGTGCCCATTCCATTTGTCCAGTTAATACTTCCTCTTAAAAATCTCCAAGAAGCTGGGTCTCCAGA
TCCCATTTAGAACCAACCAGGTGCTGAAAACACATGTAGATAATGGCCATCATCCTAAGCCCAAAGTAGAAAATGGTAGAAGGTAGTGGG
TAGAAGTCACTATATAAGGAAGGGGATGGGATTTTCCATTCTAAAAGTTTTGGAGAGGGAAATCCAGGCTATTAAAGTCACTAAATTTCT
AAGTATGTCCATTTCCCATCTCAGCTTCAAGGGAGGTGTCAGCAGTATTATCTCCACTTTCAATCTCCCTCCAAGCTCTACTCTGGAGGA
GTCTGTCCCACTCTGTCAAGTGGAATCCTTCCCTTTCCAACTCTACCTCCCTCACTCAGCTCCTTTCCCCTGATCAGAGAAAGGGATCAA
GGGGGTTGGGAGGGGGGAAAGAGACCAGCCTTGGTCCCTAAGCCTCCAGAAACGTCTTCTTAATCCCCACCTTTTCTTACTCCCAAAAAA
GAATGAACACCCCTGACTCTGGAGTGGTGTATACTGCCACATCAGTGTTTGAGTCAGTCCCCAGAGGAGAGGGGAACCCTCCTCCATCTT
TTTTGCAACATCTCATTTCTTCCTTTTGCTGTTGCTTCCCCCCTCACACACTTGGTTTTGTTCTATCCTACATTTGAGATTTCTATTTTA

>In-frame_ENST00000535309_ENST00000327892_TCGA-BR-A4QI-01A_MGST1_chr12_16507204_+_TUBB_chr6_30691716_length(amino acids)=146AA_start in transcript=142_stop in transcript=582
MMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMAVTFIGNSTAIQELFKRISEQFTAM

--------------------------------------------------------------
>In-frame_ENST00000540056_ENST00000327892_TCGA-BR-A4QI-01A_MGST1_chr12_16507204_+_TUBB_chr6_30691716_length(transcript)=1716nt_BP=229nt
GGCAGATGGAAGACTTGGGGGGGTCTCTGCCAGCTGGAAGTGCTTGGCTCCACTTAGCAGCTAAACTTAGCTTTTCAATCGATCGCTTTT
GAAAGGGAATTGTATTTCTGTCCCCGTGCGGGTAATGGATGATGAAGTATTCATGGCTTTTGCATCCTATGCAACAATTATTCTTTCAAA
AATGATGCTTATGAGTACTGCAACTGCATTCTATAGATTGACAAGAAAGTCTTCGATGCCAAGAACATGATGGCTGCCTGTGACCCCCGC
CACGGCCGATACCTCACCGTGGCTGCTGTCTTCCGTGGTCGGATGTCCATGAAGGAGGTCGATGAGCAGATGCTTAACGTGCAGAACAAG
AACAGCAGCTACTTTGTGGAATGGATCCCCAACAATGTCAAGACAGCCGTCTGTGACATCCCACCTCGTGGCCTCAAGATGGCAGTCACC
TTCATTGGCAATAGCACAGCCATCCAGGAGCTCTTCAAGCGCATCTCGGAGCAGTTCACTGCCATGTTCCGCCGGAAGGCCTTCCTCCAC
TGGTACACAGGCGAGGGCATGGACGAGATGGAGTTCACCGAGGCTGAGAGCAACATGAACGACCTCGTCTCTGAGTATCAGCAGTACCAG
GATGCCACCGCAGAAGAGGAGGAGGATTTCGGTGAGGAGGCCGAAGAGGAGGCCTAAGGCAGAGCCCCCATCACCTCAGGCTTCTCAGTT
CCCTTAGCCGTCTTACTCAACTGCCCCTTTCCTCTCCCTCAGAATTTGTGTTTGCTGCCTCTATCTTGTTTTTTGTTTTTTCTTCTGGGG
GGGGTCTAGAACAGTGCCTGGCACATAGTAGGCGCTCAATAAATACTTGTTTGTTGAATGTCTCCTCTCTCTTTCCACTCTGGGAAACCT
AGGTTTCTGCCATTCTGGGTGACCCTGTATTTCTTTCTGGTGCCCATTCCATTTGTCCAGTTAATACTTCCTCTTAAAAATCTCCAAGAA
GCTGGGTCTCCAGATCCCATTTAGAACCAACCAGGTGCTGAAAACACATGTAGATAATGGCCATCATCCTAAGCCCAAAGTAGAAAATGG
TAGAAGGTAGTGGGTAGAAGTCACTATATAAGGAAGGGGATGGGATTTTCCATTCTAAAAGTTTTGGAGAGGGAAATCCAGGCTATTAAA
GTCACTAAATTTCTAAGTATGTCCATTTCCCATCTCAGCTTCAAGGGAGGTGTCAGCAGTATTATCTCCACTTTCAATCTCCCTCCAAGC
TCTACTCTGGAGGAGTCTGTCCCACTCTGTCAAGTGGAATCCTTCCCTTTCCAACTCTACCTCCCTCACTCAGCTCCTTTCCCCTGATCA
GAGAAAGGGATCAAGGGGGTTGGGAGGGGGGAAAGAGACCAGCCTTGGTCCCTAAGCCTCCAGAAACGTCTTCTTAATCCCCACCTTTTC
TTACTCCCAAAAAAGAATGAACACCCCTGACTCTGGAGTGGTGTATACTGCCACATCAGTGTTTGAGTCAGTCCCCAGAGGAGAGGGGAA
CCCTCCTCCATCTTTTTTGCAACATCTCATTTCTTCCTTTTGCTGTTGCTTCCCCCCTCACACACTTGGTTTTGTTCTATCCTACATTTG
AGATTTCTATTTTATGTTGAACTTGCTGCTTTTTTTCATATTGAAAAGATGACATCGCCCCAAGAGCCAAAAATAAATGGGAATTGAAAA

>In-frame_ENST00000540056_ENST00000327892_TCGA-BR-A4QI-01A_MGST1_chr12_16507204_+_TUBB_chr6_30691716_length(amino acids)=146AA_start in transcript=246_stop in transcript=686
MMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMAVTFIGNSTAIQELFKRISEQFTAM

--------------------------------------------------------------
>In-frame_ENST00000396209_ENST00000327892_TCGA-BR-A4QI-01A_MGST1_chr12_16507204_+_TUBB_chr6_30691716_length(transcript)=1716nt_BP=229nt
GGCAGATGGAAGACTTGGGGGGGTCTCTGCCAGCTGGAAGTGCTTGGCTCCACTTAGCAGCTAAACTTAGCTTTTCAATCGATCGCTTTT
GAAAGGGAATTGTATTTCTGTCCCCGTGCGGGTAATGGATGATGAAGTATTCATGGCTTTTGCATCCTATGCAACAATTATTCTTTCAAA
AATGATGCTTATGAGTACTGCAACTGCATTCTATAGATTGACAAGAAAGTCTTCGATGCCAAGAACATGATGGCTGCCTGTGACCCCCGC
CACGGCCGATACCTCACCGTGGCTGCTGTCTTCCGTGGTCGGATGTCCATGAAGGAGGTCGATGAGCAGATGCTTAACGTGCAGAACAAG
AACAGCAGCTACTTTGTGGAATGGATCCCCAACAATGTCAAGACAGCCGTCTGTGACATCCCACCTCGTGGCCTCAAGATGGCAGTCACC
TTCATTGGCAATAGCACAGCCATCCAGGAGCTCTTCAAGCGCATCTCGGAGCAGTTCACTGCCATGTTCCGCCGGAAGGCCTTCCTCCAC
TGGTACACAGGCGAGGGCATGGACGAGATGGAGTTCACCGAGGCTGAGAGCAACATGAACGACCTCGTCTCTGAGTATCAGCAGTACCAG
GATGCCACCGCAGAAGAGGAGGAGGATTTCGGTGAGGAGGCCGAAGAGGAGGCCTAAGGCAGAGCCCCCATCACCTCAGGCTTCTCAGTT
CCCTTAGCCGTCTTACTCAACTGCCCCTTTCCTCTCCCTCAGAATTTGTGTTTGCTGCCTCTATCTTGTTTTTTGTTTTTTCTTCTGGGG
GGGGTCTAGAACAGTGCCTGGCACATAGTAGGCGCTCAATAAATACTTGTTTGTTGAATGTCTCCTCTCTCTTTCCACTCTGGGAAACCT
AGGTTTCTGCCATTCTGGGTGACCCTGTATTTCTTTCTGGTGCCCATTCCATTTGTCCAGTTAATACTTCCTCTTAAAAATCTCCAAGAA
GCTGGGTCTCCAGATCCCATTTAGAACCAACCAGGTGCTGAAAACACATGTAGATAATGGCCATCATCCTAAGCCCAAAGTAGAAAATGG
TAGAAGGTAGTGGGTAGAAGTCACTATATAAGGAAGGGGATGGGATTTTCCATTCTAAAAGTTTTGGAGAGGGAAATCCAGGCTATTAAA
GTCACTAAATTTCTAAGTATGTCCATTTCCCATCTCAGCTTCAAGGGAGGTGTCAGCAGTATTATCTCCACTTTCAATCTCCCTCCAAGC
TCTACTCTGGAGGAGTCTGTCCCACTCTGTCAAGTGGAATCCTTCCCTTTCCAACTCTACCTCCCTCACTCAGCTCCTTTCCCCTGATCA
GAGAAAGGGATCAAGGGGGTTGGGAGGGGGGAAAGAGACCAGCCTTGGTCCCTAAGCCTCCAGAAACGTCTTCTTAATCCCCACCTTTTC
TTACTCCCAAAAAAGAATGAACACCCCTGACTCTGGAGTGGTGTATACTGCCACATCAGTGTTTGAGTCAGTCCCCAGAGGAGAGGGGAA
CCCTCCTCCATCTTTTTTGCAACATCTCATTTCTTCCTTTTGCTGTTGCTTCCCCCCTCACACACTTGGTTTTGTTCTATCCTACATTTG
AGATTTCTATTTTATGTTGAACTTGCTGCTTTTTTTCATATTGAAAAGATGACATCGCCCCAAGAGCCAAAAATAAATGGGAATTGAAAA

>In-frame_ENST00000396209_ENST00000327892_TCGA-BR-A4QI-01A_MGST1_chr12_16507204_+_TUBB_chr6_30691716_length(amino acids)=146AA_start in transcript=246_stop in transcript=686
MMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMAVTFIGNSTAIQELFKRISEQFTAM

--------------------------------------------------------------
>In-frame_ENST00000396207_ENST00000327892_TCGA-BR-A4QI-01A_MGST1_chr12_16507204_+_TUBB_chr6_30691716_length(transcript)=1646nt_BP=159nt
GAATTCAAGTCCTAAAGCCTACAGTTTTGAATACTACTGAAATGACAAGTTGTAATGGATGATGAAGTATTCATGGCTTTTGCATCCTAT
GCAACAATTATTCTTTCAAAAATGATGCTTATGAGTACTGCAACTGCATTCTATAGATTGACAAGAAAGTCTTCGATGCCAAGAACATGA
TGGCTGCCTGTGACCCCCGCCACGGCCGATACCTCACCGTGGCTGCTGTCTTCCGTGGTCGGATGTCCATGAAGGAGGTCGATGAGCAGA
TGCTTAACGTGCAGAACAAGAACAGCAGCTACTTTGTGGAATGGATCCCCAACAATGTCAAGACAGCCGTCTGTGACATCCCACCTCGTG
GCCTCAAGATGGCAGTCACCTTCATTGGCAATAGCACAGCCATCCAGGAGCTCTTCAAGCGCATCTCGGAGCAGTTCACTGCCATGTTCC
GCCGGAAGGCCTTCCTCCACTGGTACACAGGCGAGGGCATGGACGAGATGGAGTTCACCGAGGCTGAGAGCAACATGAACGACCTCGTCT
CTGAGTATCAGCAGTACCAGGATGCCACCGCAGAAGAGGAGGAGGATTTCGGTGAGGAGGCCGAAGAGGAGGCCTAAGGCAGAGCCCCCA
TCACCTCAGGCTTCTCAGTTCCCTTAGCCGTCTTACTCAACTGCCCCTTTCCTCTCCCTCAGAATTTGTGTTTGCTGCCTCTATCTTGTT
TTTTGTTTTTTCTTCTGGGGGGGGTCTAGAACAGTGCCTGGCACATAGTAGGCGCTCAATAAATACTTGTTTGTTGAATGTCTCCTCTCT
CTTTCCACTCTGGGAAACCTAGGTTTCTGCCATTCTGGGTGACCCTGTATTTCTTTCTGGTGCCCATTCCATTTGTCCAGTTAATACTTC
CTCTTAAAAATCTCCAAGAAGCTGGGTCTCCAGATCCCATTTAGAACCAACCAGGTGCTGAAAACACATGTAGATAATGGCCATCATCCT
AAGCCCAAAGTAGAAAATGGTAGAAGGTAGTGGGTAGAAGTCACTATATAAGGAAGGGGATGGGATTTTCCATTCTAAAAGTTTTGGAGA
GGGAAATCCAGGCTATTAAAGTCACTAAATTTCTAAGTATGTCCATTTCCCATCTCAGCTTCAAGGGAGGTGTCAGCAGTATTATCTCCA
CTTTCAATCTCCCTCCAAGCTCTACTCTGGAGGAGTCTGTCCCACTCTGTCAAGTGGAATCCTTCCCTTTCCAACTCTACCTCCCTCACT
CAGCTCCTTTCCCCTGATCAGAGAAAGGGATCAAGGGGGTTGGGAGGGGGGAAAGAGACCAGCCTTGGTCCCTAAGCCTCCAGAAACGTC
TTCTTAATCCCCACCTTTTCTTACTCCCAAAAAAGAATGAACACCCCTGACTCTGGAGTGGTGTATACTGCCACATCAGTGTTTGAGTCA
GTCCCCAGAGGAGAGGGGAACCCTCCTCCATCTTTTTTGCAACATCTCATTTCTTCCTTTTGCTGTTGCTTCCCCCCTCACACACTTGGT
TTTGTTCTATCCTACATTTGAGATTTCTATTTTATGTTGAACTTGCTGCTTTTTTTCATATTGAAAAGATGACATCGCCCCAAGAGCCAA

>In-frame_ENST00000396207_ENST00000327892_TCGA-BR-A4QI-01A_MGST1_chr12_16507204_+_TUBB_chr6_30691716_length(amino acids)=146AA_start in transcript=176_stop in transcript=616
MMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMAVTFIGNSTAIQELFKRISEQFTAM

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for MGST1-TUBB

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for MGST1-TUBB

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner	Gene	UniProtAcc	DrugBank ID	Drug name	Drug activity	Drug type	Drug status
Hgene	MGST1	P10620	DB03310	Glutathione disulfide	Activator	Small molecule	Approved\|Experimental\|Investigational
Hgene	MGST1	P10620	DB03310	Glutathione disulfide	Activator	Small molecule	Approved\|Experimental\|Investigational
Hgene	MGST1	P10620	DB03310	Glutathione disulfide	Activator	Small molecule	Approved\|Experimental\|Investigational
Hgene	MGST1	P10620	DB00143	Glutathione		Small molecule	Approved\|Investigational\|Nutraceutical
Hgene	MGST1	P10620	DB00143	Glutathione		Small molecule	Approved\|Investigational\|Nutraceutical
Hgene	MGST1	P10620	DB00143	Glutathione		Small molecule	Approved\|Investigational\|Nutraceutical

Top

Related Diseases for MGST1-TUBB

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner	Gene	Disease ID	Disease name	# pubmeds	Source
Hgene	MGST1	C0270715	Degenerative Diseases, Central Nervous System	1	CTD_human
Hgene	MGST1	C0524851	Neurodegenerative Disorders	1	CTD_human
Hgene	MGST1	C0751733	Degenerative Diseases, Spinal Cord	1	CTD_human
Tgene	TUBB	C4014283	CORTICAL DYSPLASIA, COMPLEX, WITH OTHER BRAIN MALFORMATIONS 6	3	CTD_human;GENOMICS_ENGLAND;UNIPROT
Tgene	TUBB	C0473586	Michelin tire baby syndrome	1	ORPHANET
Tgene	TUBB	C4551592	SKIN CREASES, CONGENITAL SYMMETRIC CIRCUMFERENTIAL, 1	1	GENOMICS_ENGLAND;UNIPROT