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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:MIEN1-TEX2 (FusionGDB2 ID:53305)

Fusion Gene Summary for MIEN1-TEX2

check button Fusion gene summary
Fusion gene informationFusion gene name: MIEN1-TEX2
Fusion gene ID: 53305
HgeneTgene
Gene symbol

MIEN1

TEX2

Gene ID

84299

55852

Gene namemigration and invasion enhancer 1testis expressed 2
SynonymsC17orf37|C35|ORB3|RDX12|XTP4HT008|TMEM96
Cytomap

17q12

17q23.3

Type of geneprotein-codingprotein-coding
Descriptionmigration and invasion enhancer 1HBV X-transactivated gene 4 proteinHBV XAg-transactivated protein 4protein C17orf37testis-expressed protein 2testis expressed sequence 2testis-expressed sequence 2 proteintransmembrane protein 96
Modification date2020031320200313
UniProtAcc

Q9BRT3

.
Ensembl transtripts involved in fusion geneENST00000474210, ENST00000394231, 
ENST00000577810, 		ENST00000258991, 
ENST00000583097, ENST00000584379, 
ENST00000581812, 
Fusion gene scores* DoF score10 X 6 X 7=42012 X 12 X 5=720
# samples 1418
** MAII scorelog2(14/420*10)=-1.58496250072116
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(18/720*10)=-2
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: MIEN1 [Title/Abstract] AND TEX2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointMIEN1(37886447)-TEX2(62238293), # samples:1
MIEN1(37886446)-TEX2(62238293), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneMIEN1

GO:0030335

positive regulation of cell migration

21628459

HgeneMIEN1

GO:0043066

negative regulation of apoptotic process

21068479

HgeneMIEN1

GO:0051491

positive regulation of filopodium assembly

21628459


check buttonFusion gene breakpoints across MIEN1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across TEX2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4READTCGA-AG-3902-01AMIEN1chr17

37886447

-TEX2chr17

62238293

-
ChimerDB4READTCGA-AG-3902MIEN1chr17

37886446

-TEX2chr17

62238293

-


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Fusion Gene ORF analysis for MIEN1-TEX2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
intron-3CDSENST00000474210ENST00000258991MIEN1chr17

37886447

-TEX2chr17

62238293

-
intron-3CDSENST00000474210ENST00000583097MIEN1chr17

37886447

-TEX2chr17

62238293

-
intron-3CDSENST00000474210ENST00000584379MIEN1chr17

37886447

-TEX2chr17

62238293

-
intron-intronENST00000474210ENST00000581812MIEN1chr17

37886447

-TEX2chr17

62238293

-
In-frameENST00000394231ENST00000258991MIEN1chr17

37886447

-TEX2chr17

62238293

-
In-frameENST00000394231ENST00000583097MIEN1chr17

37886447

-TEX2chr17

62238293

-
In-frameENST00000394231ENST00000584379MIEN1chr17

37886447

-TEX2chr17

62238293

-
5CDS-intronENST00000394231ENST00000581812MIEN1chr17

37886447

-TEX2chr17

62238293

-
In-frameENST00000577810ENST00000258991MIEN1chr17

37886447

-TEX2chr17

62238293

-
In-frameENST00000577810ENST00000583097MIEN1chr17

37886447

-TEX2chr17

62238293

-
In-frameENST00000577810ENST00000584379MIEN1chr17

37886447

-TEX2chr17

62238293

-
5CDS-intronENST00000577810ENST00000581812MIEN1chr17

37886447

-TEX2chr17

62238293

-
intron-3CDSENST00000474210ENST00000258991MIEN1chr17

37886446

-TEX2chr17

62238293

-
intron-3CDSENST00000474210ENST00000583097MIEN1chr17

37886446

-TEX2chr17

62238293

-
intron-3CDSENST00000474210ENST00000584379MIEN1chr17

37886446

-TEX2chr17

62238293

-
intron-intronENST00000474210ENST00000581812MIEN1chr17

37886446

-TEX2chr17

62238293

-
In-frameENST00000394231ENST00000258991MIEN1chr17

37886446

-TEX2chr17

62238293

-
In-frameENST00000394231ENST00000583097MIEN1chr17

37886446

-TEX2chr17

62238293

-
In-frameENST00000394231ENST00000584379MIEN1chr17

37886446

-TEX2chr17

62238293

-
5CDS-intronENST00000394231ENST00000581812MIEN1chr17

37886446

-TEX2chr17

62238293

-
In-frameENST00000577810ENST00000258991MIEN1chr17

37886446

-TEX2chr17

62238293

-
In-frameENST00000577810ENST00000583097MIEN1chr17

37886446

-TEX2chr17

62238293

-
In-frameENST00000577810ENST00000584379MIEN1chr17

37886446

-TEX2chr17

62238293

-
5CDS-intronENST00000577810ENST00000581812MIEN1chr17

37886446

-TEX2chr17

62238293

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000394231MIEN1chr1737886447-ENST00000258991TEX2chr1762238293-2934479191191390
ENST00000394231MIEN1chr1737886447-ENST00000583097TEX2chr1762238293-2487479191191390
ENST00000394231MIEN1chr1737886447-ENST00000584379TEX2chr1762238293-2474479191191390
ENST00000577810MIEN1chr1737886447-ENST00000258991TEX2chr1762238293-265720215914299
ENST00000577810MIEN1chr1737886447-ENST00000583097TEX2chr1762238293-221020215914299
ENST00000577810MIEN1chr1737886447-ENST00000584379TEX2chr1762238293-219720215914299
ENST00000394231MIEN1chr1737886446-ENST00000258991TEX2chr1762238293-2934479191191390
ENST00000394231MIEN1chr1737886446-ENST00000583097TEX2chr1762238293-2487479191191390
ENST00000394231MIEN1chr1737886446-ENST00000584379TEX2chr1762238293-2474479191191390
ENST00000577810MIEN1chr1737886446-ENST00000258991TEX2chr1762238293-265720215914299
ENST00000577810MIEN1chr1737886446-ENST00000583097TEX2chr1762238293-221020215914299
ENST00000577810MIEN1chr1737886446-ENST00000584379TEX2chr1762238293-219720215914299

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000394231ENST00000258991MIEN1chr1737886447-TEX2chr1762238293-0.0011608440.9988392
ENST00000394231ENST00000583097MIEN1chr1737886447-TEX2chr1762238293-0.0019983990.99800164
ENST00000394231ENST00000584379MIEN1chr1737886447-TEX2chr1762238293-0.0020243040.99797565
ENST00000577810ENST00000258991MIEN1chr1737886447-TEX2chr1762238293-0.0010118420.9989881
ENST00000577810ENST00000583097MIEN1chr1737886447-TEX2chr1762238293-0.0013516990.99864835
ENST00000577810ENST00000584379MIEN1chr1737886447-TEX2chr1762238293-0.0013660030.9986339
ENST00000394231ENST00000258991MIEN1chr1737886446-TEX2chr1762238293-0.0011608440.9988392
ENST00000394231ENST00000583097MIEN1chr1737886446-TEX2chr1762238293-0.0019983990.99800164
ENST00000394231ENST00000584379MIEN1chr1737886446-TEX2chr1762238293-0.0020243040.99797565
ENST00000577810ENST00000258991MIEN1chr1737886446-TEX2chr1762238293-0.0010118420.9989881
ENST00000577810ENST00000583097MIEN1chr1737886446-TEX2chr1762238293-0.0013516990.99864835
ENST00000577810ENST00000584379MIEN1chr1737886446-TEX2chr1762238293-0.0013660030.9986339

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Fusion Genomic Features for MIEN1-TEX2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for MIEN1-TEX2


check button Go to

FGviewer for the breakpoints of chr17:37886447-chr17:62238293

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
MIEN1

Q9BRT3

.
FUNCTION: Increases cell migration by inducing filopodia formation at the leading edge of migrating cells. Plays a role in regulation of apoptosis, possibly through control of CASP3. May be involved in a redox-related process. {ECO:0000269|PubMed:19503095, ECO:0000269|PubMed:21628459}.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneTEX2chr17:37886446chr17:62238293ENST000002589916121039_1042897.33333333333341135.0Compositional biasNote=Poly-Pro
TgeneTEX2chr17:37886446chr17:62238293ENST000005830976121039_1042890.33333333333341128.0Compositional biasNote=Poly-Pro
TgeneTEX2chr17:37886446chr17:62238293ENST000005843796121039_1042890.33333333333341128.0Compositional biasNote=Poly-Pro
TgeneTEX2chr17:37886447chr17:62238293ENST000002589916121039_1042897.33333333333341135.0Compositional biasNote=Poly-Pro
TgeneTEX2chr17:37886447chr17:62238293ENST000005830976121039_1042890.33333333333341128.0Compositional biasNote=Poly-Pro
TgeneTEX2chr17:37886447chr17:62238293ENST000005843796121039_1042890.33333333333341128.0Compositional biasNote=Poly-Pro

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneTEX2chr17:37886446chr17:62238293ENST00000258991612138_141897.33333333333341135.0Compositional biasNote=Poly-Ser
TgeneTEX2chr17:37886446chr17:62238293ENST00000258991612159_162897.33333333333341135.0Compositional biasNote=Poly-Ser
TgeneTEX2chr17:37886446chr17:62238293ENST0000025899161243_51897.33333333333341135.0Compositional biasNote=Poly-Glu
TgeneTEX2chr17:37886446chr17:62238293ENST00000258991612816_821897.33333333333341135.0Compositional biasNote=Poly-Glu
TgeneTEX2chr17:37886446chr17:62238293ENST00000583097612138_141890.33333333333341128.0Compositional biasNote=Poly-Ser
TgeneTEX2chr17:37886446chr17:62238293ENST00000583097612159_162890.33333333333341128.0Compositional biasNote=Poly-Ser
TgeneTEX2chr17:37886446chr17:62238293ENST0000058309761243_51890.33333333333341128.0Compositional biasNote=Poly-Glu
TgeneTEX2chr17:37886446chr17:62238293ENST00000583097612816_821890.33333333333341128.0Compositional biasNote=Poly-Glu
TgeneTEX2chr17:37886446chr17:62238293ENST00000584379612138_141890.33333333333341128.0Compositional biasNote=Poly-Ser
TgeneTEX2chr17:37886446chr17:62238293ENST00000584379612159_162890.33333333333341128.0Compositional biasNote=Poly-Ser
TgeneTEX2chr17:37886446chr17:62238293ENST0000058437961243_51890.33333333333341128.0Compositional biasNote=Poly-Glu
TgeneTEX2chr17:37886446chr17:62238293ENST00000584379612816_821890.33333333333341128.0Compositional biasNote=Poly-Glu
TgeneTEX2chr17:37886447chr17:62238293ENST00000258991612138_141897.33333333333341135.0Compositional biasNote=Poly-Ser
TgeneTEX2chr17:37886447chr17:62238293ENST00000258991612159_162897.33333333333341135.0Compositional biasNote=Poly-Ser
TgeneTEX2chr17:37886447chr17:62238293ENST0000025899161243_51897.33333333333341135.0Compositional biasNote=Poly-Glu
TgeneTEX2chr17:37886447chr17:62238293ENST00000258991612816_821897.33333333333341135.0Compositional biasNote=Poly-Glu
TgeneTEX2chr17:37886447chr17:62238293ENST00000583097612138_141890.33333333333341128.0Compositional biasNote=Poly-Ser
TgeneTEX2chr17:37886447chr17:62238293ENST00000583097612159_162890.33333333333341128.0Compositional biasNote=Poly-Ser
TgeneTEX2chr17:37886447chr17:62238293ENST0000058309761243_51890.33333333333341128.0Compositional biasNote=Poly-Glu
TgeneTEX2chr17:37886447chr17:62238293ENST00000583097612816_821890.33333333333341128.0Compositional biasNote=Poly-Glu
TgeneTEX2chr17:37886447chr17:62238293ENST00000584379612138_141890.33333333333341128.0Compositional biasNote=Poly-Ser
TgeneTEX2chr17:37886447chr17:62238293ENST00000584379612159_162890.33333333333341128.0Compositional biasNote=Poly-Ser
TgeneTEX2chr17:37886447chr17:62238293ENST0000058437961243_51890.33333333333341128.0Compositional biasNote=Poly-Glu
TgeneTEX2chr17:37886447chr17:62238293ENST00000584379612816_821890.33333333333341128.0Compositional biasNote=Poly-Glu
TgeneTEX2chr17:37886446chr17:62238293ENST00000258991612816_1101897.33333333333341135.0DomainSMP-LTD
TgeneTEX2chr17:37886446chr17:62238293ENST00000583097612816_1101890.33333333333341128.0DomainSMP-LTD
TgeneTEX2chr17:37886446chr17:62238293ENST00000584379612816_1101890.33333333333341128.0DomainSMP-LTD
TgeneTEX2chr17:37886447chr17:62238293ENST00000258991612816_1101897.33333333333341135.0DomainSMP-LTD
TgeneTEX2chr17:37886447chr17:62238293ENST00000583097612816_1101890.33333333333341128.0DomainSMP-LTD
TgeneTEX2chr17:37886447chr17:62238293ENST00000584379612816_1101890.33333333333341128.0DomainSMP-LTD
TgeneTEX2chr17:37886446chr17:62238293ENST00000258991612475_495897.33333333333341135.0TransmembraneHelical
TgeneTEX2chr17:37886446chr17:62238293ENST00000258991612497_517897.33333333333341135.0TransmembraneHelical
TgeneTEX2chr17:37886446chr17:62238293ENST00000583097612475_495890.33333333333341128.0TransmembraneHelical
TgeneTEX2chr17:37886446chr17:62238293ENST00000583097612497_517890.33333333333341128.0TransmembraneHelical
TgeneTEX2chr17:37886446chr17:62238293ENST00000584379612475_495890.33333333333341128.0TransmembraneHelical
TgeneTEX2chr17:37886446chr17:62238293ENST00000584379612497_517890.33333333333341128.0TransmembraneHelical
TgeneTEX2chr17:37886447chr17:62238293ENST00000258991612475_495897.33333333333341135.0TransmembraneHelical
TgeneTEX2chr17:37886447chr17:62238293ENST00000258991612497_517897.33333333333341135.0TransmembraneHelical
TgeneTEX2chr17:37886447chr17:62238293ENST00000583097612475_495890.33333333333341128.0TransmembraneHelical
TgeneTEX2chr17:37886447chr17:62238293ENST00000583097612497_517890.33333333333341128.0TransmembraneHelical
TgeneTEX2chr17:37886447chr17:62238293ENST00000584379612475_495890.33333333333341128.0TransmembraneHelical
TgeneTEX2chr17:37886447chr17:62238293ENST00000584379612497_517890.33333333333341128.0TransmembraneHelical


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Fusion Gene Sequence for MIEN1-TEX2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000394231_ENST00000258991_TCGA-AG-3902-01A_MIEN1_chr17_37886447_-_TEX2_chr17_62238293_length(transcript)=2934nt_BP=479nt
CATTAGAGTAAATGAAGCCATGAAGTCCAGCGGACACCGGGAGTGGGGAGTGGGGAAGCCCGGCACTCCGGGAGACCGGGCCAGGGAAGG
AGGGTCTGGACCGGACCCAGCCCCTGCCCGGGGAGCGAGCTCCGGAGCTGCCCTACGAGGTCAAAACGTAGCAGTGGCGGAGACCCGCAG
GGGGCGCCCGAACGCCACCCTCGGCCCCTCCCCGCTCCAGAGGCCCCGCCCCGTCACGTGCCCGCGGTTCGCGTCACACCCGGAAGCAGG
GGCCCGAGCGGAGCCGGCCGCGATGAGCGGGGAGCCGGGGCAGACGTCCGTAGCGCCCCCTCCCGAGGAGGTCGAGCCGGGCAGTGGGGT
CCGCATCGTGGTGGAGTACTGTGAACCCTGCGGCTTCGAGGCGACCTACCTGGAGCTGGCCAGTGCTGTGAAGGAGCAGTATCCGGGCAT
CGAGATCGAGTCGCGCCTCGGGGGCACAGGACTCTGGATTGATTTGGAAATGTCCTACAATGGGTCCTTTCTGATGACTCTCGAGACCAA
AATGAATTTGACCAAACTAGGTAAAGAGCCTCTTGTTGAAGCCCTGAAGGTTGGAGAAATTGGCAAAGAAGGTTGCAGGCCCCGGGCATT
CTGTCTGGCGGACAGCGATGAGGAATCCTCCAGCGCTGGCTCCTCCGAGGAAGACGATGCCCCAGAGCCCAGCGGGGGAGACAAACAGCT
CCTCCCAGGGGCTGAAGGGTACGTTGGAGGTCATCGAACAAGTAAGATTATGAGGTTTGTTGATAAAATTACCAAGTCAAAATATTTCCA
AAAAGCAACAGAGACAGAGTTTATTAAAAAGAAGATCGAAGAAGTCTCCAACACACCCCTGCTGCTCACTGTTGAAGTACAAGAATGTAG
AGGAACCTTGGCGGTCAACATTCCACCACCCCCGACTGACCGAGTATGGTATGGTTTCCGAAAGCCACCACATGTGGAGCTGAAAGCTCG
GCCAAAACTTGGAGAGAGAGAAGTGACTTTAGTTCATGTGACAGACTGGATAGAGAAGAAACTGGAGCAAGAGTTTCAGAAAGTTTTTGT
CATGCCAAACATGGATGATGTTTATATCACTATAATGCACTCAGCCATGGACCCTCGCTCTACTTCCTGCCTCCTGAAAGACCCACCTGT
GGAGGCTGCTGATCAGCCATGATGGGTGATGTCAGATGTTCCCCATATTGTGACATCGAGCTGGATGTGTGGGGTTCTTGGCCGCCATCT
GTACTGTAGCACTGGCCTCTGTGCCACAGCTACTGTTTCTTAAAGGACTGCTTCTGCCCTCTGCCTGCCAGTGCCCATTCCACTGTGAGG
TGTCATTCCCTGCATCTAGTGACAACTGTCTGGATTGCCTGCTGCAAAGCTTTGATTTGGCAAAGGAGACCATGGAAGAATCATGGTGGA
TCCAGAAGTTATACGTGACCCACACCATGGCTTTTAAAAGTCTACCCATGTTTGTGGCAGCAAATGAGCACAGTAAGAGCAAAGCTGAAC
AACTTGCCTCCTCTACTCCTCCAAAGCTTTTCTTCAGGCAGCCGGTGCACAGTGGACTTTTTCACTTCTATACTTTGTATGCGGCCTTCC
ACACTTCCAGAGAATGTCAGTGTGCAATGTGTCTGGAGGGTGGGGAGAGGAATTCTGTGAGCCTTTTCATTTCGGTGACAGAAGAGATGG
GCAGAGCAACTTATTTTCCACATTAAATTGTGCATTTGGGAAGCAAGTAGCCATAGTACACACACAACACGCTATCAGCTTGGGTAAGGA
CAGTGGGATTTATGTGAACATCAGGCAAAGCCATGAGATCAAACCATCCCAAGCCTTTCACCAATGAGGTACAACCACCTGGGGGCTAGC
TAATCTTGAATGTTTTCCTGAGACAGGAGCGTATGTGAAAACATCAAACACTGCACATGACAGGATGGGTCCTCTCATACAGATGGGATG
GGGTTAGAAAGCCAGAGCCAGTTTTTCCATCTGGCGTTTCCTGTGTCCTCCAGGTTTATATGGGAATCGAAACAGTTTGTTAATCTGATT
GGGAGAGTTCCATGGGCAGATTTCCCTTCCTGAAGGCCAAAACGGAGAACTGCTCTCTTTAATTATTTCAAGAGTCAAGACCAAAAGTTT
GCTCAGCATCACACTACATCTCAAAATTAATGTTGCCAACTTAATTTTGTGCATTTGTGTCAGAATGTTTAGTTTACAAGGTTGGGGGCT
CTCTTTGCTTCGAGAAGTAAACCTAATACCATTTTTTTATTGTTTAAAGCTGCATTCAACGTCAAAATTACCTTGGGTAACTTTTGATAA
CTTACATGTGTGGACAAAGCTAATAGTGGTTTTTTAAACAGCACCTTGCCTGAACATGACTTTAAAGAAATTAATATATTGAAAACATGT
TTGAACCCTTATTTTAATTGCACCATTAAAACATTTGACTTAAATTGTTTGACCATTCCAGTTGGTGTACTGTTCTGATTTTTCGTTGTG
TAGGCCGATCTGCCTGTCAGAGTCCACGTGTCCTGGTCACTGGTCTTTATAATTGTTGTGCAATAACTAAAGGCTAAGGACTAGATGCAC
TATCGTGTAAAGAGATTACACATGACTGTACCATGTTGCACTTAATCAAATAGTATGTGGGGATTTAAAATCGCTTGCATTGTTTCACAA
AATAAATATCTCAATGTCAAATACTAGATAAGCATCTAAGTCATTTCTACGGAATCCTGTTCAGATAGGGGCACAATAAAATGAGTACAG
AGCACCGGGGCCCTCACCTGGCAATCGCAGCTTTCATTTACTGCGTTGATCACTGCCCAGTCCTAAGGCTACAAAGCCATCCTCACTACA

>In-frame_ENST00000394231_ENST00000258991_TCGA-AG-3902-01A_MIEN1_chr17_37886447_-_TEX2_chr17_62238293_length(amino acids)=390AA_start in transcript=19_stop in transcript=1191
MKSSGHREWGVGKPGTPGDRAREGGSGPDPAPARGASSGAALRGQNVAVAETRRGRPNATLGPSPLQRPRPVTCPRFASHPEAGARAEPA
AMSGEPGQTSVAPPPEEVEPGSGVRIVVEYCEPCGFEATYLELASAVKEQYPGIEIESRLGGTGLWIDLEMSYNGSFLMTLETKMNLTKL
GKEPLVEALKVGEIGKEGCRPRAFCLADSDEESSSAGSSEEDDAPEPSGGDKQLLPGAEGYVGGHRTSKIMRFVDKITKSKYFQKATETE
FIKKKIEEVSNTPLLLTVEVQECRGTLAVNIPPPPTDRVWYGFRKPPHVELKARPKLGEREVTLVHVTDWIEKKLEQEFQKVFVMPNMDD

--------------------------------------------------------------
>In-frame_ENST00000394231_ENST00000583097_TCGA-AG-3902-01A_MIEN1_chr17_37886447_-_TEX2_chr17_62238293_length(transcript)=2487nt_BP=479nt
CATTAGAGTAAATGAAGCCATGAAGTCCAGCGGACACCGGGAGTGGGGAGTGGGGAAGCCCGGCACTCCGGGAGACCGGGCCAGGGAAGG
AGGGTCTGGACCGGACCCAGCCCCTGCCCGGGGAGCGAGCTCCGGAGCTGCCCTACGAGGTCAAAACGTAGCAGTGGCGGAGACCCGCAG
GGGGCGCCCGAACGCCACCCTCGGCCCCTCCCCGCTCCAGAGGCCCCGCCCCGTCACGTGCCCGCGGTTCGCGTCACACCCGGAAGCAGG
GGCCCGAGCGGAGCCGGCCGCGATGAGCGGGGAGCCGGGGCAGACGTCCGTAGCGCCCCCTCCCGAGGAGGTCGAGCCGGGCAGTGGGGT
CCGCATCGTGGTGGAGTACTGTGAACCCTGCGGCTTCGAGGCGACCTACCTGGAGCTGGCCAGTGCTGTGAAGGAGCAGTATCCGGGCAT
CGAGATCGAGTCGCGCCTCGGGGGCACAGGACTCTGGATTGATTTGGAAATGTCCTACAATGGGTCCTTTCTGATGACTCTCGAGACCAA
AATGAATTTGACCAAACTAGGTAAAGAGCCTCTTGTTGAAGCCCTGAAGGTTGGAGAAATTGGCAAAGAAGGTTGCAGGCCCCGGGCATT
CTGTCTGGCGGACAGCGATGAGGAATCCTCCAGCGCTGGCTCCTCCGAGGAAGACGATGCCCCAGAGCCCAGCGGGGGAGACAAACAGCT
CCTCCCAGGGGCTGAAGGGTACGTTGGAGGTCATCGAACAAGTAAGATTATGAGGTTTGTTGATAAAATTACCAAGTCAAAATATTTCCA
AAAAGCAACAGAGACAGAGTTTATTAAAAAGAAGATCGAAGAAGTCTCCAACACACCCCTGCTGCTCACTGTTGAAGTACAAGAATGTAG
AGGAACCTTGGCGGTCAACATTCCACCACCCCCGACTGACCGAGTATGGTATGGTTTCCGAAAGCCACCACATGTGGAGCTGAAAGCTCG
GCCAAAACTTGGAGAGAGAGAAGTGACTTTAGTTCATGTGACAGACTGGATAGAGAAGAAACTGGAGCAAGAGTTTCAGAAAGTTTTTGT
CATGCCAAACATGGATGATGTTTATATCACTATAATGCACTCAGCCATGGACCCTCGCTCTACTTCCTGCCTCCTGAAAGACCCACCTGT
GGAGGCTGCTGATCAGCCATGATGGGTGATGTCAGATGTTCCCCATATTGTGACATCGAGCTGGATGTGTGGGGTTCTTGGCCGCCATCT
GTACTGTAGCACTGGCCTCTGTGCCACAGCTACTGTTTCTTAAAGGACTGCTTCTGCCCTCTGCCTGCCAGTGCCCATTCCACTGTGAGG
TGTCATTCCCTGCATCTAGTGACAACTGTCTGGATTGCCTGCTGCAAAGCTTTGATTTGGCAAAGGAGACCATGGAAGAATCATGGTGGA
TCCAGAAGTTATACGTGACCCACACCATGGCTTTTAAAAGTCTACCCATGTTTGTGGCAGCAAATGAGCACAGTAAGAGCAAAGCTGAAC
AACTTGCCTCCTCTACTCCTCCAAAGCTTTTCTTCAGGCAGCCGGTGCACAGTGGACTTTTTCACTTCTATACTTTGTATGCGGCCTTCC
ACACTTCCAGAGAATGTCAGTGTGCAATGTGTCTGGAGGGTGGGGAGAGGAATTCTGTGAGCCTTTTCATTTCGGTGACAGAAGAGATGG
GCAGAGCAACTTATTTTCCACATTAAATTGTGCATTTGGGAAGCAAGTAGCCATAGTACACACACAACACGCTATCAGCTTGGGTAAGGA
CAGTGGGATTTATGTGAACATCAGGCAAAGCCATGAGATCAAACCATCCCAAGCCTTTCACCAATGAGGTACAACCACCTGGGGGCTAGC
TAATCTTGAATGTTTTCCTGAGACAGGAGCGTATGTGAAAACATCAAACACTGCACATGACAGGATGGGTCCTCTCATACAGATGGGATG
GGGTTAGAAAGCCAGAGCCAGTTTTTCCATCTGGCGTTTCCTGTGTCCTCCAGGTTTATATGGGAATCGAAACAGTTTGTTAATCTGATT
GGGAGAGTTCCATGGGCAGATTTCCCTTCCTGAAGGCCAAAACGGAGAACTGCTCTCTTTAATTATTTCAAGAGTCAAGACCAAAAGTTT
GCTCAGCATCACACTACATCTCAAAATTAATGTTGCCAACTTAATTTTGTGCATTTGTGTCAGAATGTTTAGTTTACAAGGTTGGGGGCT
CTCTTTGCTTCGAGAAGTAAACCTAATACCATTTTTTTATTGTTTAAAGCTGCATTCAACGTCAAAATTACCTTGGGTAACTTTTGATAA
CTTACATGTGTGGACAAAGCTAATAGTGGTTTTTTAAACAGCACCTTGCCTGAACATGACTTTAAAGAAATTAATATATTGAAAACATGT

>In-frame_ENST00000394231_ENST00000583097_TCGA-AG-3902-01A_MIEN1_chr17_37886447_-_TEX2_chr17_62238293_length(amino acids)=390AA_start in transcript=19_stop in transcript=1191
MKSSGHREWGVGKPGTPGDRAREGGSGPDPAPARGASSGAALRGQNVAVAETRRGRPNATLGPSPLQRPRPVTCPRFASHPEAGARAEPA
AMSGEPGQTSVAPPPEEVEPGSGVRIVVEYCEPCGFEATYLELASAVKEQYPGIEIESRLGGTGLWIDLEMSYNGSFLMTLETKMNLTKL
GKEPLVEALKVGEIGKEGCRPRAFCLADSDEESSSAGSSEEDDAPEPSGGDKQLLPGAEGYVGGHRTSKIMRFVDKITKSKYFQKATETE
FIKKKIEEVSNTPLLLTVEVQECRGTLAVNIPPPPTDRVWYGFRKPPHVELKARPKLGEREVTLVHVTDWIEKKLEQEFQKVFVMPNMDD

--------------------------------------------------------------
>In-frame_ENST00000394231_ENST00000584379_TCGA-AG-3902-01A_MIEN1_chr17_37886447_-_TEX2_chr17_62238293_length(transcript)=2474nt_BP=479nt
CATTAGAGTAAATGAAGCCATGAAGTCCAGCGGACACCGGGAGTGGGGAGTGGGGAAGCCCGGCACTCCGGGAGACCGGGCCAGGGAAGG
AGGGTCTGGACCGGACCCAGCCCCTGCCCGGGGAGCGAGCTCCGGAGCTGCCCTACGAGGTCAAAACGTAGCAGTGGCGGAGACCCGCAG
GGGGCGCCCGAACGCCACCCTCGGCCCCTCCCCGCTCCAGAGGCCCCGCCCCGTCACGTGCCCGCGGTTCGCGTCACACCCGGAAGCAGG
GGCCCGAGCGGAGCCGGCCGCGATGAGCGGGGAGCCGGGGCAGACGTCCGTAGCGCCCCCTCCCGAGGAGGTCGAGCCGGGCAGTGGGGT
CCGCATCGTGGTGGAGTACTGTGAACCCTGCGGCTTCGAGGCGACCTACCTGGAGCTGGCCAGTGCTGTGAAGGAGCAGTATCCGGGCAT
CGAGATCGAGTCGCGCCTCGGGGGCACAGGACTCTGGATTGATTTGGAAATGTCCTACAATGGGTCCTTTCTGATGACTCTCGAGACCAA
AATGAATTTGACCAAACTAGGTAAAGAGCCTCTTGTTGAAGCCCTGAAGGTTGGAGAAATTGGCAAAGAAGGTTGCAGGCCCCGGGCATT
CTGTCTGGCGGACAGCGATGAGGAATCCTCCAGCGCTGGCTCCTCCGAGGAAGACGATGCCCCAGAGCCCAGCGGGGGAGACAAACAGCT
CCTCCCAGGGGCTGAAGGGTACGTTGGAGGTCATCGAACAAGTAAGATTATGAGGTTTGTTGATAAAATTACCAAGTCAAAATATTTCCA
AAAAGCAACAGAGACAGAGTTTATTAAAAAGAAGATCGAAGAAGTCTCCAACACACCCCTGCTGCTCACTGTTGAAGTACAAGAATGTAG
AGGAACCTTGGCGGTCAACATTCCACCACCCCCGACTGACCGAGTATGGTATGGTTTCCGAAAGCCACCACATGTGGAGCTGAAAGCTCG
GCCAAAACTTGGAGAGAGAGAAGTGACTTTAGTTCATGTGACAGACTGGATAGAGAAGAAACTGGAGCAAGAGTTTCAGAAAGTTTTTGT
CATGCCAAACATGGATGATGTTTATATCACTATAATGCACTCAGCCATGGACCCTCGCTCTACTTCCTGCCTCCTGAAAGACCCACCTGT
GGAGGCTGCTGATCAGCCATGATGGGTGATGTCAGATGTTCCCCATATTGTGACATCGAGCTGGATGTGTGGGGTTCTTGGCCGCCATCT
GTACTGTAGCACTGGCCTCTGTGCCACAGCTACTGTTTCTTAAAGGACTGCTTCTGCCCTCTGCCTGCCAGTGCCCATTCCACTGTGAGG
TGTCATTCCCTGCATCTAGTGACAACTGTCTGGATTGCCTGCTGCAAAGCTTTGATTTGGCAAAGGAGACCATGGAAGAATCATGGTGGA
TCCAGAAGTTATACGTGACCCACACCATGGCTTTTAAAAGTCTACCCATGTTTGTGGCAGCAAATGAGCACAGTAAGAGCAAAGCTGAAC
AACTTGCCTCCTCTACTCCTCCAAAGCTTTTCTTCAGGCAGCCGGTGCACAGTGGACTTTTTCACTTCTATACTTTGTATGCGGCCTTCC
ACACTTCCAGAGAATGTCAGTGTGCAATGTGTCTGGAGGGTGGGGAGAGGAATTCTGTGAGCCTTTTCATTTCGGTGACAGAAGAGATGG
GCAGAGCAACTTATTTTCCACATTAAATTGTGCATTTGGGAAGCAAGTAGCCATAGTACACACACAACACGCTATCAGCTTGGGTAAGGA
CAGTGGGATTTATGTGAACATCAGGCAAAGCCATGAGATCAAACCATCCCAAGCCTTTCACCAATGAGGTACAACCACCTGGGGGCTAGC
TAATCTTGAATGTTTTCCTGAGACAGGAGCGTATGTGAAAACATCAAACACTGCACATGACAGGATGGGTCCTCTCATACAGATGGGATG
GGGTTAGAAAGCCAGAGCCAGTTTTTCCATCTGGCGTTTCCTGTGTCCTCCAGGTTTATATGGGAATCGAAACAGTTTGTTAATCTGATT
GGGAGAGTTCCATGGGCAGATTTCCCTTCCTGAAGGCCAAAACGGAGAACTGCTCTCTTTAATTATTTCAAGAGTCAAGACCAAAAGTTT
GCTCAGCATCACACTACATCTCAAAATTAATGTTGCCAACTTAATTTTGTGCATTTGTGTCAGAATGTTTAGTTTACAAGGTTGGGGGCT
CTCTTTGCTTCGAGAAGTAAACCTAATACCATTTTTTTATTGTTTAAAGCTGCATTCAACGTCAAAATTACCTTGGGTAACTTTTGATAA
CTTACATGTGTGGACAAAGCTAATAGTGGTTTTTTAAACAGCACCTTGCCTGAACATGACTTTAAAGAAATTAATATATTGAAAACATGT

>In-frame_ENST00000394231_ENST00000584379_TCGA-AG-3902-01A_MIEN1_chr17_37886447_-_TEX2_chr17_62238293_length(amino acids)=390AA_start in transcript=19_stop in transcript=1191
MKSSGHREWGVGKPGTPGDRAREGGSGPDPAPARGASSGAALRGQNVAVAETRRGRPNATLGPSPLQRPRPVTCPRFASHPEAGARAEPA
AMSGEPGQTSVAPPPEEVEPGSGVRIVVEYCEPCGFEATYLELASAVKEQYPGIEIESRLGGTGLWIDLEMSYNGSFLMTLETKMNLTKL
GKEPLVEALKVGEIGKEGCRPRAFCLADSDEESSSAGSSEEDDAPEPSGGDKQLLPGAEGYVGGHRTSKIMRFVDKITKSKYFQKATETE
FIKKKIEEVSNTPLLLTVEVQECRGTLAVNIPPPPTDRVWYGFRKPPHVELKARPKLGEREVTLVHVTDWIEKKLEQEFQKVFVMPNMDD

--------------------------------------------------------------
>In-frame_ENST00000577810_ENST00000258991_TCGA-AG-3902-01A_MIEN1_chr17_37886447_-_TEX2_chr17_62238293_length(transcript)=2657nt_BP=202nt
GCGGAGCCGGCCGCGATGAGCGGGGAGCCGGGGCAGACGTCCGTAGCGCCCCCTCCCGAGGAGGTCGAGCCGGGCAGTGGGGTCCGCATC
GTGGTGGAGTACTGTGAACCCTGCGGCTTCGAGGCGACCTACCTGGAGCTGGCCAGTGCTGTGAAGGAGCAGTATCCGGGCATCGAGATC
GAGTCGCGCCTCGGGGGCACAGGACTCTGGATTGATTTGGAAATGTCCTACAATGGGTCCTTTCTGATGACTCTCGAGACCAAAATGAAT
TTGACCAAACTAGGTAAAGAGCCTCTTGTTGAAGCCCTGAAGGTTGGAGAAATTGGCAAAGAAGGTTGCAGGCCCCGGGCATTCTGTCTG
GCGGACAGCGATGAGGAATCCTCCAGCGCTGGCTCCTCCGAGGAAGACGATGCCCCAGAGCCCAGCGGGGGAGACAAACAGCTCCTCCCA
GGGGCTGAAGGGTACGTTGGAGGTCATCGAACAAGTAAGATTATGAGGTTTGTTGATAAAATTACCAAGTCAAAATATTTCCAAAAAGCA
ACAGAGACAGAGTTTATTAAAAAGAAGATCGAAGAAGTCTCCAACACACCCCTGCTGCTCACTGTTGAAGTACAAGAATGTAGAGGAACC
TTGGCGGTCAACATTCCACCACCCCCGACTGACCGAGTATGGTATGGTTTCCGAAAGCCACCACATGTGGAGCTGAAAGCTCGGCCAAAA
CTTGGAGAGAGAGAAGTGACTTTAGTTCATGTGACAGACTGGATAGAGAAGAAACTGGAGCAAGAGTTTCAGAAAGTTTTTGTCATGCCA
AACATGGATGATGTTTATATCACTATAATGCACTCAGCCATGGACCCTCGCTCTACTTCCTGCCTCCTGAAAGACCCACCTGTGGAGGCT
GCTGATCAGCCATGATGGGTGATGTCAGATGTTCCCCATATTGTGACATCGAGCTGGATGTGTGGGGTTCTTGGCCGCCATCTGTACTGT
AGCACTGGCCTCTGTGCCACAGCTACTGTTTCTTAAAGGACTGCTTCTGCCCTCTGCCTGCCAGTGCCCATTCCACTGTGAGGTGTCATT
CCCTGCATCTAGTGACAACTGTCTGGATTGCCTGCTGCAAAGCTTTGATTTGGCAAAGGAGACCATGGAAGAATCATGGTGGATCCAGAA
GTTATACGTGACCCACACCATGGCTTTTAAAAGTCTACCCATGTTTGTGGCAGCAAATGAGCACAGTAAGAGCAAAGCTGAACAACTTGC
CTCCTCTACTCCTCCAAAGCTTTTCTTCAGGCAGCCGGTGCACAGTGGACTTTTTCACTTCTATACTTTGTATGCGGCCTTCCACACTTC
CAGAGAATGTCAGTGTGCAATGTGTCTGGAGGGTGGGGAGAGGAATTCTGTGAGCCTTTTCATTTCGGTGACAGAAGAGATGGGCAGAGC
AACTTATTTTCCACATTAAATTGTGCATTTGGGAAGCAAGTAGCCATAGTACACACACAACACGCTATCAGCTTGGGTAAGGACAGTGGG
ATTTATGTGAACATCAGGCAAAGCCATGAGATCAAACCATCCCAAGCCTTTCACCAATGAGGTACAACCACCTGGGGGCTAGCTAATCTT
GAATGTTTTCCTGAGACAGGAGCGTATGTGAAAACATCAAACACTGCACATGACAGGATGGGTCCTCTCATACAGATGGGATGGGGTTAG
AAAGCCAGAGCCAGTTTTTCCATCTGGCGTTTCCTGTGTCCTCCAGGTTTATATGGGAATCGAAACAGTTTGTTAATCTGATTGGGAGAG
TTCCATGGGCAGATTTCCCTTCCTGAAGGCCAAAACGGAGAACTGCTCTCTTTAATTATTTCAAGAGTCAAGACCAAAAGTTTGCTCAGC
ATCACACTACATCTCAAAATTAATGTTGCCAACTTAATTTTGTGCATTTGTGTCAGAATGTTTAGTTTACAAGGTTGGGGGCTCTCTTTG
CTTCGAGAAGTAAACCTAATACCATTTTTTTATTGTTTAAAGCTGCATTCAACGTCAAAATTACCTTGGGTAACTTTTGATAACTTACAT
GTGTGGACAAAGCTAATAGTGGTTTTTTAAACAGCACCTTGCCTGAACATGACTTTAAAGAAATTAATATATTGAAAACATGTTTGAACC
CTTATTTTAATTGCACCATTAAAACATTTGACTTAAATTGTTTGACCATTCCAGTTGGTGTACTGTTCTGATTTTTCGTTGTGTAGGCCG
ATCTGCCTGTCAGAGTCCACGTGTCCTGGTCACTGGTCTTTATAATTGTTGTGCAATAACTAAAGGCTAAGGACTAGATGCACTATCGTG
TAAAGAGATTACACATGACTGTACCATGTTGCACTTAATCAAATAGTATGTGGGGATTTAAAATCGCTTGCATTGTTTCACAAAATAAAT
ATCTCAATGTCAAATACTAGATAAGCATCTAAGTCATTTCTACGGAATCCTGTTCAGATAGGGGCACAATAAAATGAGTACAGAGCACCG
GGGCCCTCACCTGGCAATCGCAGCTTTCATTTACTGCGTTGATCACTGCCCAGTCCTAAGGCTACAAAGCCATCCTCACTACATCCTTCA

>In-frame_ENST00000577810_ENST00000258991_TCGA-AG-3902-01A_MIEN1_chr17_37886447_-_TEX2_chr17_62238293_length(amino acids)=299AA_start in transcript=15_stop in transcript=914
MSGEPGQTSVAPPPEEVEPGSGVRIVVEYCEPCGFEATYLELASAVKEQYPGIEIESRLGGTGLWIDLEMSYNGSFLMTLETKMNLTKLG
KEPLVEALKVGEIGKEGCRPRAFCLADSDEESSSAGSSEEDDAPEPSGGDKQLLPGAEGYVGGHRTSKIMRFVDKITKSKYFQKATETEF
IKKKIEEVSNTPLLLTVEVQECRGTLAVNIPPPPTDRVWYGFRKPPHVELKARPKLGEREVTLVHVTDWIEKKLEQEFQKVFVMPNMDDV

--------------------------------------------------------------
>In-frame_ENST00000577810_ENST00000583097_TCGA-AG-3902-01A_MIEN1_chr17_37886447_-_TEX2_chr17_62238293_length(transcript)=2210nt_BP=202nt
GCGGAGCCGGCCGCGATGAGCGGGGAGCCGGGGCAGACGTCCGTAGCGCCCCCTCCCGAGGAGGTCGAGCCGGGCAGTGGGGTCCGCATC
GTGGTGGAGTACTGTGAACCCTGCGGCTTCGAGGCGACCTACCTGGAGCTGGCCAGTGCTGTGAAGGAGCAGTATCCGGGCATCGAGATC
GAGTCGCGCCTCGGGGGCACAGGACTCTGGATTGATTTGGAAATGTCCTACAATGGGTCCTTTCTGATGACTCTCGAGACCAAAATGAAT
TTGACCAAACTAGGTAAAGAGCCTCTTGTTGAAGCCCTGAAGGTTGGAGAAATTGGCAAAGAAGGTTGCAGGCCCCGGGCATTCTGTCTG
GCGGACAGCGATGAGGAATCCTCCAGCGCTGGCTCCTCCGAGGAAGACGATGCCCCAGAGCCCAGCGGGGGAGACAAACAGCTCCTCCCA
GGGGCTGAAGGGTACGTTGGAGGTCATCGAACAAGTAAGATTATGAGGTTTGTTGATAAAATTACCAAGTCAAAATATTTCCAAAAAGCA
ACAGAGACAGAGTTTATTAAAAAGAAGATCGAAGAAGTCTCCAACACACCCCTGCTGCTCACTGTTGAAGTACAAGAATGTAGAGGAACC
TTGGCGGTCAACATTCCACCACCCCCGACTGACCGAGTATGGTATGGTTTCCGAAAGCCACCACATGTGGAGCTGAAAGCTCGGCCAAAA
CTTGGAGAGAGAGAAGTGACTTTAGTTCATGTGACAGACTGGATAGAGAAGAAACTGGAGCAAGAGTTTCAGAAAGTTTTTGTCATGCCA
AACATGGATGATGTTTATATCACTATAATGCACTCAGCCATGGACCCTCGCTCTACTTCCTGCCTCCTGAAAGACCCACCTGTGGAGGCT
GCTGATCAGCCATGATGGGTGATGTCAGATGTTCCCCATATTGTGACATCGAGCTGGATGTGTGGGGTTCTTGGCCGCCATCTGTACTGT
AGCACTGGCCTCTGTGCCACAGCTACTGTTTCTTAAAGGACTGCTTCTGCCCTCTGCCTGCCAGTGCCCATTCCACTGTGAGGTGTCATT
CCCTGCATCTAGTGACAACTGTCTGGATTGCCTGCTGCAAAGCTTTGATTTGGCAAAGGAGACCATGGAAGAATCATGGTGGATCCAGAA
GTTATACGTGACCCACACCATGGCTTTTAAAAGTCTACCCATGTTTGTGGCAGCAAATGAGCACAGTAAGAGCAAAGCTGAACAACTTGC
CTCCTCTACTCCTCCAAAGCTTTTCTTCAGGCAGCCGGTGCACAGTGGACTTTTTCACTTCTATACTTTGTATGCGGCCTTCCACACTTC
CAGAGAATGTCAGTGTGCAATGTGTCTGGAGGGTGGGGAGAGGAATTCTGTGAGCCTTTTCATTTCGGTGACAGAAGAGATGGGCAGAGC
AACTTATTTTCCACATTAAATTGTGCATTTGGGAAGCAAGTAGCCATAGTACACACACAACACGCTATCAGCTTGGGTAAGGACAGTGGG
ATTTATGTGAACATCAGGCAAAGCCATGAGATCAAACCATCCCAAGCCTTTCACCAATGAGGTACAACCACCTGGGGGCTAGCTAATCTT
GAATGTTTTCCTGAGACAGGAGCGTATGTGAAAACATCAAACACTGCACATGACAGGATGGGTCCTCTCATACAGATGGGATGGGGTTAG
AAAGCCAGAGCCAGTTTTTCCATCTGGCGTTTCCTGTGTCCTCCAGGTTTATATGGGAATCGAAACAGTTTGTTAATCTGATTGGGAGAG
TTCCATGGGCAGATTTCCCTTCCTGAAGGCCAAAACGGAGAACTGCTCTCTTTAATTATTTCAAGAGTCAAGACCAAAAGTTTGCTCAGC
ATCACACTACATCTCAAAATTAATGTTGCCAACTTAATTTTGTGCATTTGTGTCAGAATGTTTAGTTTACAAGGTTGGGGGCTCTCTTTG
CTTCGAGAAGTAAACCTAATACCATTTTTTTATTGTTTAAAGCTGCATTCAACGTCAAAATTACCTTGGGTAACTTTTGATAACTTACAT
GTGTGGACAAAGCTAATAGTGGTTTTTTAAACAGCACCTTGCCTGAACATGACTTTAAAGAAATTAATATATTGAAAACATGTTTGAACC

>In-frame_ENST00000577810_ENST00000583097_TCGA-AG-3902-01A_MIEN1_chr17_37886447_-_TEX2_chr17_62238293_length(amino acids)=299AA_start in transcript=15_stop in transcript=914
MSGEPGQTSVAPPPEEVEPGSGVRIVVEYCEPCGFEATYLELASAVKEQYPGIEIESRLGGTGLWIDLEMSYNGSFLMTLETKMNLTKLG
KEPLVEALKVGEIGKEGCRPRAFCLADSDEESSSAGSSEEDDAPEPSGGDKQLLPGAEGYVGGHRTSKIMRFVDKITKSKYFQKATETEF
IKKKIEEVSNTPLLLTVEVQECRGTLAVNIPPPPTDRVWYGFRKPPHVELKARPKLGEREVTLVHVTDWIEKKLEQEFQKVFVMPNMDDV

--------------------------------------------------------------
>In-frame_ENST00000577810_ENST00000584379_TCGA-AG-3902-01A_MIEN1_chr17_37886447_-_TEX2_chr17_62238293_length(transcript)=2197nt_BP=202nt
GCGGAGCCGGCCGCGATGAGCGGGGAGCCGGGGCAGACGTCCGTAGCGCCCCCTCCCGAGGAGGTCGAGCCGGGCAGTGGGGTCCGCATC
GTGGTGGAGTACTGTGAACCCTGCGGCTTCGAGGCGACCTACCTGGAGCTGGCCAGTGCTGTGAAGGAGCAGTATCCGGGCATCGAGATC
GAGTCGCGCCTCGGGGGCACAGGACTCTGGATTGATTTGGAAATGTCCTACAATGGGTCCTTTCTGATGACTCTCGAGACCAAAATGAAT
TTGACCAAACTAGGTAAAGAGCCTCTTGTTGAAGCCCTGAAGGTTGGAGAAATTGGCAAAGAAGGTTGCAGGCCCCGGGCATTCTGTCTG
GCGGACAGCGATGAGGAATCCTCCAGCGCTGGCTCCTCCGAGGAAGACGATGCCCCAGAGCCCAGCGGGGGAGACAAACAGCTCCTCCCA
GGGGCTGAAGGGTACGTTGGAGGTCATCGAACAAGTAAGATTATGAGGTTTGTTGATAAAATTACCAAGTCAAAATATTTCCAAAAAGCA
ACAGAGACAGAGTTTATTAAAAAGAAGATCGAAGAAGTCTCCAACACACCCCTGCTGCTCACTGTTGAAGTACAAGAATGTAGAGGAACC
TTGGCGGTCAACATTCCACCACCCCCGACTGACCGAGTATGGTATGGTTTCCGAAAGCCACCACATGTGGAGCTGAAAGCTCGGCCAAAA
CTTGGAGAGAGAGAAGTGACTTTAGTTCATGTGACAGACTGGATAGAGAAGAAACTGGAGCAAGAGTTTCAGAAAGTTTTTGTCATGCCA
AACATGGATGATGTTTATATCACTATAATGCACTCAGCCATGGACCCTCGCTCTACTTCCTGCCTCCTGAAAGACCCACCTGTGGAGGCT
GCTGATCAGCCATGATGGGTGATGTCAGATGTTCCCCATATTGTGACATCGAGCTGGATGTGTGGGGTTCTTGGCCGCCATCTGTACTGT
AGCACTGGCCTCTGTGCCACAGCTACTGTTTCTTAAAGGACTGCTTCTGCCCTCTGCCTGCCAGTGCCCATTCCACTGTGAGGTGTCATT
CCCTGCATCTAGTGACAACTGTCTGGATTGCCTGCTGCAAAGCTTTGATTTGGCAAAGGAGACCATGGAAGAATCATGGTGGATCCAGAA
GTTATACGTGACCCACACCATGGCTTTTAAAAGTCTACCCATGTTTGTGGCAGCAAATGAGCACAGTAAGAGCAAAGCTGAACAACTTGC
CTCCTCTACTCCTCCAAAGCTTTTCTTCAGGCAGCCGGTGCACAGTGGACTTTTTCACTTCTATACTTTGTATGCGGCCTTCCACACTTC
CAGAGAATGTCAGTGTGCAATGTGTCTGGAGGGTGGGGAGAGGAATTCTGTGAGCCTTTTCATTTCGGTGACAGAAGAGATGGGCAGAGC
AACTTATTTTCCACATTAAATTGTGCATTTGGGAAGCAAGTAGCCATAGTACACACACAACACGCTATCAGCTTGGGTAAGGACAGTGGG
ATTTATGTGAACATCAGGCAAAGCCATGAGATCAAACCATCCCAAGCCTTTCACCAATGAGGTACAACCACCTGGGGGCTAGCTAATCTT
GAATGTTTTCCTGAGACAGGAGCGTATGTGAAAACATCAAACACTGCACATGACAGGATGGGTCCTCTCATACAGATGGGATGGGGTTAG
AAAGCCAGAGCCAGTTTTTCCATCTGGCGTTTCCTGTGTCCTCCAGGTTTATATGGGAATCGAAACAGTTTGTTAATCTGATTGGGAGAG
TTCCATGGGCAGATTTCCCTTCCTGAAGGCCAAAACGGAGAACTGCTCTCTTTAATTATTTCAAGAGTCAAGACCAAAAGTTTGCTCAGC
ATCACACTACATCTCAAAATTAATGTTGCCAACTTAATTTTGTGCATTTGTGTCAGAATGTTTAGTTTACAAGGTTGGGGGCTCTCTTTG
CTTCGAGAAGTAAACCTAATACCATTTTTTTATTGTTTAAAGCTGCATTCAACGTCAAAATTACCTTGGGTAACTTTTGATAACTTACAT
GTGTGGACAAAGCTAATAGTGGTTTTTTAAACAGCACCTTGCCTGAACATGACTTTAAAGAAATTAATATATTGAAAACATGTTTGAACC

>In-frame_ENST00000577810_ENST00000584379_TCGA-AG-3902-01A_MIEN1_chr17_37886447_-_TEX2_chr17_62238293_length(amino acids)=299AA_start in transcript=15_stop in transcript=914
MSGEPGQTSVAPPPEEVEPGSGVRIVVEYCEPCGFEATYLELASAVKEQYPGIEIESRLGGTGLWIDLEMSYNGSFLMTLETKMNLTKLG
KEPLVEALKVGEIGKEGCRPRAFCLADSDEESSSAGSSEEDDAPEPSGGDKQLLPGAEGYVGGHRTSKIMRFVDKITKSKYFQKATETEF
IKKKIEEVSNTPLLLTVEVQECRGTLAVNIPPPPTDRVWYGFRKPPHVELKARPKLGEREVTLVHVTDWIEKKLEQEFQKVFVMPNMDDV

--------------------------------------------------------------
>In-frame_ENST00000394231_ENST00000258991_TCGA-AG-3902_MIEN1_chr17_37886446_-_TEX2_chr17_62238293_length(transcript)=2934nt_BP=479nt
CATTAGAGTAAATGAAGCCATGAAGTCCAGCGGACACCGGGAGTGGGGAGTGGGGAAGCCCGGCACTCCGGGAGACCGGGCCAGGGAAGG
AGGGTCTGGACCGGACCCAGCCCCTGCCCGGGGAGCGAGCTCCGGAGCTGCCCTACGAGGTCAAAACGTAGCAGTGGCGGAGACCCGCAG
GGGGCGCCCGAACGCCACCCTCGGCCCCTCCCCGCTCCAGAGGCCCCGCCCCGTCACGTGCCCGCGGTTCGCGTCACACCCGGAAGCAGG
GGCCCGAGCGGAGCCGGCCGCGATGAGCGGGGAGCCGGGGCAGACGTCCGTAGCGCCCCCTCCCGAGGAGGTCGAGCCGGGCAGTGGGGT
CCGCATCGTGGTGGAGTACTGTGAACCCTGCGGCTTCGAGGCGACCTACCTGGAGCTGGCCAGTGCTGTGAAGGAGCAGTATCCGGGCAT
CGAGATCGAGTCGCGCCTCGGGGGCACAGGACTCTGGATTGATTTGGAAATGTCCTACAATGGGTCCTTTCTGATGACTCTCGAGACCAA
AATGAATTTGACCAAACTAGGTAAAGAGCCTCTTGTTGAAGCCCTGAAGGTTGGAGAAATTGGCAAAGAAGGTTGCAGGCCCCGGGCATT
CTGTCTGGCGGACAGCGATGAGGAATCCTCCAGCGCTGGCTCCTCCGAGGAAGACGATGCCCCAGAGCCCAGCGGGGGAGACAAACAGCT
CCTCCCAGGGGCTGAAGGGTACGTTGGAGGTCATCGAACAAGTAAGATTATGAGGTTTGTTGATAAAATTACCAAGTCAAAATATTTCCA
AAAAGCAACAGAGACAGAGTTTATTAAAAAGAAGATCGAAGAAGTCTCCAACACACCCCTGCTGCTCACTGTTGAAGTACAAGAATGTAG
AGGAACCTTGGCGGTCAACATTCCACCACCCCCGACTGACCGAGTATGGTATGGTTTCCGAAAGCCACCACATGTGGAGCTGAAAGCTCG
GCCAAAACTTGGAGAGAGAGAAGTGACTTTAGTTCATGTGACAGACTGGATAGAGAAGAAACTGGAGCAAGAGTTTCAGAAAGTTTTTGT
CATGCCAAACATGGATGATGTTTATATCACTATAATGCACTCAGCCATGGACCCTCGCTCTACTTCCTGCCTCCTGAAAGACCCACCTGT
GGAGGCTGCTGATCAGCCATGATGGGTGATGTCAGATGTTCCCCATATTGTGACATCGAGCTGGATGTGTGGGGTTCTTGGCCGCCATCT
GTACTGTAGCACTGGCCTCTGTGCCACAGCTACTGTTTCTTAAAGGACTGCTTCTGCCCTCTGCCTGCCAGTGCCCATTCCACTGTGAGG
TGTCATTCCCTGCATCTAGTGACAACTGTCTGGATTGCCTGCTGCAAAGCTTTGATTTGGCAAAGGAGACCATGGAAGAATCATGGTGGA
TCCAGAAGTTATACGTGACCCACACCATGGCTTTTAAAAGTCTACCCATGTTTGTGGCAGCAAATGAGCACAGTAAGAGCAAAGCTGAAC
AACTTGCCTCCTCTACTCCTCCAAAGCTTTTCTTCAGGCAGCCGGTGCACAGTGGACTTTTTCACTTCTATACTTTGTATGCGGCCTTCC
ACACTTCCAGAGAATGTCAGTGTGCAATGTGTCTGGAGGGTGGGGAGAGGAATTCTGTGAGCCTTTTCATTTCGGTGACAGAAGAGATGG
GCAGAGCAACTTATTTTCCACATTAAATTGTGCATTTGGGAAGCAAGTAGCCATAGTACACACACAACACGCTATCAGCTTGGGTAAGGA
CAGTGGGATTTATGTGAACATCAGGCAAAGCCATGAGATCAAACCATCCCAAGCCTTTCACCAATGAGGTACAACCACCTGGGGGCTAGC
TAATCTTGAATGTTTTCCTGAGACAGGAGCGTATGTGAAAACATCAAACACTGCACATGACAGGATGGGTCCTCTCATACAGATGGGATG
GGGTTAGAAAGCCAGAGCCAGTTTTTCCATCTGGCGTTTCCTGTGTCCTCCAGGTTTATATGGGAATCGAAACAGTTTGTTAATCTGATT
GGGAGAGTTCCATGGGCAGATTTCCCTTCCTGAAGGCCAAAACGGAGAACTGCTCTCTTTAATTATTTCAAGAGTCAAGACCAAAAGTTT
GCTCAGCATCACACTACATCTCAAAATTAATGTTGCCAACTTAATTTTGTGCATTTGTGTCAGAATGTTTAGTTTACAAGGTTGGGGGCT
CTCTTTGCTTCGAGAAGTAAACCTAATACCATTTTTTTATTGTTTAAAGCTGCATTCAACGTCAAAATTACCTTGGGTAACTTTTGATAA
CTTACATGTGTGGACAAAGCTAATAGTGGTTTTTTAAACAGCACCTTGCCTGAACATGACTTTAAAGAAATTAATATATTGAAAACATGT
TTGAACCCTTATTTTAATTGCACCATTAAAACATTTGACTTAAATTGTTTGACCATTCCAGTTGGTGTACTGTTCTGATTTTTCGTTGTG
TAGGCCGATCTGCCTGTCAGAGTCCACGTGTCCTGGTCACTGGTCTTTATAATTGTTGTGCAATAACTAAAGGCTAAGGACTAGATGCAC
TATCGTGTAAAGAGATTACACATGACTGTACCATGTTGCACTTAATCAAATAGTATGTGGGGATTTAAAATCGCTTGCATTGTTTCACAA
AATAAATATCTCAATGTCAAATACTAGATAAGCATCTAAGTCATTTCTACGGAATCCTGTTCAGATAGGGGCACAATAAAATGAGTACAG
AGCACCGGGGCCCTCACCTGGCAATCGCAGCTTTCATTTACTGCGTTGATCACTGCCCAGTCCTAAGGCTACAAAGCCATCCTCACTACA

>In-frame_ENST00000394231_ENST00000258991_TCGA-AG-3902_MIEN1_chr17_37886446_-_TEX2_chr17_62238293_length(amino acids)=390AA_start in transcript=19_stop in transcript=1191
MKSSGHREWGVGKPGTPGDRAREGGSGPDPAPARGASSGAALRGQNVAVAETRRGRPNATLGPSPLQRPRPVTCPRFASHPEAGARAEPA
AMSGEPGQTSVAPPPEEVEPGSGVRIVVEYCEPCGFEATYLELASAVKEQYPGIEIESRLGGTGLWIDLEMSYNGSFLMTLETKMNLTKL
GKEPLVEALKVGEIGKEGCRPRAFCLADSDEESSSAGSSEEDDAPEPSGGDKQLLPGAEGYVGGHRTSKIMRFVDKITKSKYFQKATETE
FIKKKIEEVSNTPLLLTVEVQECRGTLAVNIPPPPTDRVWYGFRKPPHVELKARPKLGEREVTLVHVTDWIEKKLEQEFQKVFVMPNMDD

--------------------------------------------------------------
>In-frame_ENST00000394231_ENST00000583097_TCGA-AG-3902_MIEN1_chr17_37886446_-_TEX2_chr17_62238293_length(transcript)=2487nt_BP=479nt
CATTAGAGTAAATGAAGCCATGAAGTCCAGCGGACACCGGGAGTGGGGAGTGGGGAAGCCCGGCACTCCGGGAGACCGGGCCAGGGAAGG
AGGGTCTGGACCGGACCCAGCCCCTGCCCGGGGAGCGAGCTCCGGAGCTGCCCTACGAGGTCAAAACGTAGCAGTGGCGGAGACCCGCAG
GGGGCGCCCGAACGCCACCCTCGGCCCCTCCCCGCTCCAGAGGCCCCGCCCCGTCACGTGCCCGCGGTTCGCGTCACACCCGGAAGCAGG
GGCCCGAGCGGAGCCGGCCGCGATGAGCGGGGAGCCGGGGCAGACGTCCGTAGCGCCCCCTCCCGAGGAGGTCGAGCCGGGCAGTGGGGT
CCGCATCGTGGTGGAGTACTGTGAACCCTGCGGCTTCGAGGCGACCTACCTGGAGCTGGCCAGTGCTGTGAAGGAGCAGTATCCGGGCAT
CGAGATCGAGTCGCGCCTCGGGGGCACAGGACTCTGGATTGATTTGGAAATGTCCTACAATGGGTCCTTTCTGATGACTCTCGAGACCAA
AATGAATTTGACCAAACTAGGTAAAGAGCCTCTTGTTGAAGCCCTGAAGGTTGGAGAAATTGGCAAAGAAGGTTGCAGGCCCCGGGCATT
CTGTCTGGCGGACAGCGATGAGGAATCCTCCAGCGCTGGCTCCTCCGAGGAAGACGATGCCCCAGAGCCCAGCGGGGGAGACAAACAGCT
CCTCCCAGGGGCTGAAGGGTACGTTGGAGGTCATCGAACAAGTAAGATTATGAGGTTTGTTGATAAAATTACCAAGTCAAAATATTTCCA
AAAAGCAACAGAGACAGAGTTTATTAAAAAGAAGATCGAAGAAGTCTCCAACACACCCCTGCTGCTCACTGTTGAAGTACAAGAATGTAG
AGGAACCTTGGCGGTCAACATTCCACCACCCCCGACTGACCGAGTATGGTATGGTTTCCGAAAGCCACCACATGTGGAGCTGAAAGCTCG
GCCAAAACTTGGAGAGAGAGAAGTGACTTTAGTTCATGTGACAGACTGGATAGAGAAGAAACTGGAGCAAGAGTTTCAGAAAGTTTTTGT
CATGCCAAACATGGATGATGTTTATATCACTATAATGCACTCAGCCATGGACCCTCGCTCTACTTCCTGCCTCCTGAAAGACCCACCTGT
GGAGGCTGCTGATCAGCCATGATGGGTGATGTCAGATGTTCCCCATATTGTGACATCGAGCTGGATGTGTGGGGTTCTTGGCCGCCATCT
GTACTGTAGCACTGGCCTCTGTGCCACAGCTACTGTTTCTTAAAGGACTGCTTCTGCCCTCTGCCTGCCAGTGCCCATTCCACTGTGAGG
TGTCATTCCCTGCATCTAGTGACAACTGTCTGGATTGCCTGCTGCAAAGCTTTGATTTGGCAAAGGAGACCATGGAAGAATCATGGTGGA
TCCAGAAGTTATACGTGACCCACACCATGGCTTTTAAAAGTCTACCCATGTTTGTGGCAGCAAATGAGCACAGTAAGAGCAAAGCTGAAC
AACTTGCCTCCTCTACTCCTCCAAAGCTTTTCTTCAGGCAGCCGGTGCACAGTGGACTTTTTCACTTCTATACTTTGTATGCGGCCTTCC
ACACTTCCAGAGAATGTCAGTGTGCAATGTGTCTGGAGGGTGGGGAGAGGAATTCTGTGAGCCTTTTCATTTCGGTGACAGAAGAGATGG
GCAGAGCAACTTATTTTCCACATTAAATTGTGCATTTGGGAAGCAAGTAGCCATAGTACACACACAACACGCTATCAGCTTGGGTAAGGA
CAGTGGGATTTATGTGAACATCAGGCAAAGCCATGAGATCAAACCATCCCAAGCCTTTCACCAATGAGGTACAACCACCTGGGGGCTAGC
TAATCTTGAATGTTTTCCTGAGACAGGAGCGTATGTGAAAACATCAAACACTGCACATGACAGGATGGGTCCTCTCATACAGATGGGATG
GGGTTAGAAAGCCAGAGCCAGTTTTTCCATCTGGCGTTTCCTGTGTCCTCCAGGTTTATATGGGAATCGAAACAGTTTGTTAATCTGATT
GGGAGAGTTCCATGGGCAGATTTCCCTTCCTGAAGGCCAAAACGGAGAACTGCTCTCTTTAATTATTTCAAGAGTCAAGACCAAAAGTTT
GCTCAGCATCACACTACATCTCAAAATTAATGTTGCCAACTTAATTTTGTGCATTTGTGTCAGAATGTTTAGTTTACAAGGTTGGGGGCT
CTCTTTGCTTCGAGAAGTAAACCTAATACCATTTTTTTATTGTTTAAAGCTGCATTCAACGTCAAAATTACCTTGGGTAACTTTTGATAA
CTTACATGTGTGGACAAAGCTAATAGTGGTTTTTTAAACAGCACCTTGCCTGAACATGACTTTAAAGAAATTAATATATTGAAAACATGT

>In-frame_ENST00000394231_ENST00000583097_TCGA-AG-3902_MIEN1_chr17_37886446_-_TEX2_chr17_62238293_length(amino acids)=390AA_start in transcript=19_stop in transcript=1191
MKSSGHREWGVGKPGTPGDRAREGGSGPDPAPARGASSGAALRGQNVAVAETRRGRPNATLGPSPLQRPRPVTCPRFASHPEAGARAEPA
AMSGEPGQTSVAPPPEEVEPGSGVRIVVEYCEPCGFEATYLELASAVKEQYPGIEIESRLGGTGLWIDLEMSYNGSFLMTLETKMNLTKL
GKEPLVEALKVGEIGKEGCRPRAFCLADSDEESSSAGSSEEDDAPEPSGGDKQLLPGAEGYVGGHRTSKIMRFVDKITKSKYFQKATETE
FIKKKIEEVSNTPLLLTVEVQECRGTLAVNIPPPPTDRVWYGFRKPPHVELKARPKLGEREVTLVHVTDWIEKKLEQEFQKVFVMPNMDD

--------------------------------------------------------------
>In-frame_ENST00000394231_ENST00000584379_TCGA-AG-3902_MIEN1_chr17_37886446_-_TEX2_chr17_62238293_length(transcript)=2474nt_BP=479nt
CATTAGAGTAAATGAAGCCATGAAGTCCAGCGGACACCGGGAGTGGGGAGTGGGGAAGCCCGGCACTCCGGGAGACCGGGCCAGGGAAGG
AGGGTCTGGACCGGACCCAGCCCCTGCCCGGGGAGCGAGCTCCGGAGCTGCCCTACGAGGTCAAAACGTAGCAGTGGCGGAGACCCGCAG
GGGGCGCCCGAACGCCACCCTCGGCCCCTCCCCGCTCCAGAGGCCCCGCCCCGTCACGTGCCCGCGGTTCGCGTCACACCCGGAAGCAGG
GGCCCGAGCGGAGCCGGCCGCGATGAGCGGGGAGCCGGGGCAGACGTCCGTAGCGCCCCCTCCCGAGGAGGTCGAGCCGGGCAGTGGGGT
CCGCATCGTGGTGGAGTACTGTGAACCCTGCGGCTTCGAGGCGACCTACCTGGAGCTGGCCAGTGCTGTGAAGGAGCAGTATCCGGGCAT
CGAGATCGAGTCGCGCCTCGGGGGCACAGGACTCTGGATTGATTTGGAAATGTCCTACAATGGGTCCTTTCTGATGACTCTCGAGACCAA
AATGAATTTGACCAAACTAGGTAAAGAGCCTCTTGTTGAAGCCCTGAAGGTTGGAGAAATTGGCAAAGAAGGTTGCAGGCCCCGGGCATT
CTGTCTGGCGGACAGCGATGAGGAATCCTCCAGCGCTGGCTCCTCCGAGGAAGACGATGCCCCAGAGCCCAGCGGGGGAGACAAACAGCT
CCTCCCAGGGGCTGAAGGGTACGTTGGAGGTCATCGAACAAGTAAGATTATGAGGTTTGTTGATAAAATTACCAAGTCAAAATATTTCCA
AAAAGCAACAGAGACAGAGTTTATTAAAAAGAAGATCGAAGAAGTCTCCAACACACCCCTGCTGCTCACTGTTGAAGTACAAGAATGTAG
AGGAACCTTGGCGGTCAACATTCCACCACCCCCGACTGACCGAGTATGGTATGGTTTCCGAAAGCCACCACATGTGGAGCTGAAAGCTCG
GCCAAAACTTGGAGAGAGAGAAGTGACTTTAGTTCATGTGACAGACTGGATAGAGAAGAAACTGGAGCAAGAGTTTCAGAAAGTTTTTGT
CATGCCAAACATGGATGATGTTTATATCACTATAATGCACTCAGCCATGGACCCTCGCTCTACTTCCTGCCTCCTGAAAGACCCACCTGT
GGAGGCTGCTGATCAGCCATGATGGGTGATGTCAGATGTTCCCCATATTGTGACATCGAGCTGGATGTGTGGGGTTCTTGGCCGCCATCT
GTACTGTAGCACTGGCCTCTGTGCCACAGCTACTGTTTCTTAAAGGACTGCTTCTGCCCTCTGCCTGCCAGTGCCCATTCCACTGTGAGG
TGTCATTCCCTGCATCTAGTGACAACTGTCTGGATTGCCTGCTGCAAAGCTTTGATTTGGCAAAGGAGACCATGGAAGAATCATGGTGGA
TCCAGAAGTTATACGTGACCCACACCATGGCTTTTAAAAGTCTACCCATGTTTGTGGCAGCAAATGAGCACAGTAAGAGCAAAGCTGAAC
AACTTGCCTCCTCTACTCCTCCAAAGCTTTTCTTCAGGCAGCCGGTGCACAGTGGACTTTTTCACTTCTATACTTTGTATGCGGCCTTCC
ACACTTCCAGAGAATGTCAGTGTGCAATGTGTCTGGAGGGTGGGGAGAGGAATTCTGTGAGCCTTTTCATTTCGGTGACAGAAGAGATGG
GCAGAGCAACTTATTTTCCACATTAAATTGTGCATTTGGGAAGCAAGTAGCCATAGTACACACACAACACGCTATCAGCTTGGGTAAGGA
CAGTGGGATTTATGTGAACATCAGGCAAAGCCATGAGATCAAACCATCCCAAGCCTTTCACCAATGAGGTACAACCACCTGGGGGCTAGC
TAATCTTGAATGTTTTCCTGAGACAGGAGCGTATGTGAAAACATCAAACACTGCACATGACAGGATGGGTCCTCTCATACAGATGGGATG
GGGTTAGAAAGCCAGAGCCAGTTTTTCCATCTGGCGTTTCCTGTGTCCTCCAGGTTTATATGGGAATCGAAACAGTTTGTTAATCTGATT
GGGAGAGTTCCATGGGCAGATTTCCCTTCCTGAAGGCCAAAACGGAGAACTGCTCTCTTTAATTATTTCAAGAGTCAAGACCAAAAGTTT
GCTCAGCATCACACTACATCTCAAAATTAATGTTGCCAACTTAATTTTGTGCATTTGTGTCAGAATGTTTAGTTTACAAGGTTGGGGGCT
CTCTTTGCTTCGAGAAGTAAACCTAATACCATTTTTTTATTGTTTAAAGCTGCATTCAACGTCAAAATTACCTTGGGTAACTTTTGATAA
CTTACATGTGTGGACAAAGCTAATAGTGGTTTTTTAAACAGCACCTTGCCTGAACATGACTTTAAAGAAATTAATATATTGAAAACATGT

>In-frame_ENST00000394231_ENST00000584379_TCGA-AG-3902_MIEN1_chr17_37886446_-_TEX2_chr17_62238293_length(amino acids)=390AA_start in transcript=19_stop in transcript=1191
MKSSGHREWGVGKPGTPGDRAREGGSGPDPAPARGASSGAALRGQNVAVAETRRGRPNATLGPSPLQRPRPVTCPRFASHPEAGARAEPA
AMSGEPGQTSVAPPPEEVEPGSGVRIVVEYCEPCGFEATYLELASAVKEQYPGIEIESRLGGTGLWIDLEMSYNGSFLMTLETKMNLTKL
GKEPLVEALKVGEIGKEGCRPRAFCLADSDEESSSAGSSEEDDAPEPSGGDKQLLPGAEGYVGGHRTSKIMRFVDKITKSKYFQKATETE
FIKKKIEEVSNTPLLLTVEVQECRGTLAVNIPPPPTDRVWYGFRKPPHVELKARPKLGEREVTLVHVTDWIEKKLEQEFQKVFVMPNMDD

--------------------------------------------------------------
>In-frame_ENST00000577810_ENST00000258991_TCGA-AG-3902_MIEN1_chr17_37886446_-_TEX2_chr17_62238293_length(transcript)=2657nt_BP=202nt
GCGGAGCCGGCCGCGATGAGCGGGGAGCCGGGGCAGACGTCCGTAGCGCCCCCTCCCGAGGAGGTCGAGCCGGGCAGTGGGGTCCGCATC
GTGGTGGAGTACTGTGAACCCTGCGGCTTCGAGGCGACCTACCTGGAGCTGGCCAGTGCTGTGAAGGAGCAGTATCCGGGCATCGAGATC
GAGTCGCGCCTCGGGGGCACAGGACTCTGGATTGATTTGGAAATGTCCTACAATGGGTCCTTTCTGATGACTCTCGAGACCAAAATGAAT
TTGACCAAACTAGGTAAAGAGCCTCTTGTTGAAGCCCTGAAGGTTGGAGAAATTGGCAAAGAAGGTTGCAGGCCCCGGGCATTCTGTCTG
GCGGACAGCGATGAGGAATCCTCCAGCGCTGGCTCCTCCGAGGAAGACGATGCCCCAGAGCCCAGCGGGGGAGACAAACAGCTCCTCCCA
GGGGCTGAAGGGTACGTTGGAGGTCATCGAACAAGTAAGATTATGAGGTTTGTTGATAAAATTACCAAGTCAAAATATTTCCAAAAAGCA
ACAGAGACAGAGTTTATTAAAAAGAAGATCGAAGAAGTCTCCAACACACCCCTGCTGCTCACTGTTGAAGTACAAGAATGTAGAGGAACC
TTGGCGGTCAACATTCCACCACCCCCGACTGACCGAGTATGGTATGGTTTCCGAAAGCCACCACATGTGGAGCTGAAAGCTCGGCCAAAA
CTTGGAGAGAGAGAAGTGACTTTAGTTCATGTGACAGACTGGATAGAGAAGAAACTGGAGCAAGAGTTTCAGAAAGTTTTTGTCATGCCA
AACATGGATGATGTTTATATCACTATAATGCACTCAGCCATGGACCCTCGCTCTACTTCCTGCCTCCTGAAAGACCCACCTGTGGAGGCT
GCTGATCAGCCATGATGGGTGATGTCAGATGTTCCCCATATTGTGACATCGAGCTGGATGTGTGGGGTTCTTGGCCGCCATCTGTACTGT
AGCACTGGCCTCTGTGCCACAGCTACTGTTTCTTAAAGGACTGCTTCTGCCCTCTGCCTGCCAGTGCCCATTCCACTGTGAGGTGTCATT
CCCTGCATCTAGTGACAACTGTCTGGATTGCCTGCTGCAAAGCTTTGATTTGGCAAAGGAGACCATGGAAGAATCATGGTGGATCCAGAA
GTTATACGTGACCCACACCATGGCTTTTAAAAGTCTACCCATGTTTGTGGCAGCAAATGAGCACAGTAAGAGCAAAGCTGAACAACTTGC
CTCCTCTACTCCTCCAAAGCTTTTCTTCAGGCAGCCGGTGCACAGTGGACTTTTTCACTTCTATACTTTGTATGCGGCCTTCCACACTTC
CAGAGAATGTCAGTGTGCAATGTGTCTGGAGGGTGGGGAGAGGAATTCTGTGAGCCTTTTCATTTCGGTGACAGAAGAGATGGGCAGAGC
AACTTATTTTCCACATTAAATTGTGCATTTGGGAAGCAAGTAGCCATAGTACACACACAACACGCTATCAGCTTGGGTAAGGACAGTGGG
ATTTATGTGAACATCAGGCAAAGCCATGAGATCAAACCATCCCAAGCCTTTCACCAATGAGGTACAACCACCTGGGGGCTAGCTAATCTT
GAATGTTTTCCTGAGACAGGAGCGTATGTGAAAACATCAAACACTGCACATGACAGGATGGGTCCTCTCATACAGATGGGATGGGGTTAG
AAAGCCAGAGCCAGTTTTTCCATCTGGCGTTTCCTGTGTCCTCCAGGTTTATATGGGAATCGAAACAGTTTGTTAATCTGATTGGGAGAG
TTCCATGGGCAGATTTCCCTTCCTGAAGGCCAAAACGGAGAACTGCTCTCTTTAATTATTTCAAGAGTCAAGACCAAAAGTTTGCTCAGC
ATCACACTACATCTCAAAATTAATGTTGCCAACTTAATTTTGTGCATTTGTGTCAGAATGTTTAGTTTACAAGGTTGGGGGCTCTCTTTG
CTTCGAGAAGTAAACCTAATACCATTTTTTTATTGTTTAAAGCTGCATTCAACGTCAAAATTACCTTGGGTAACTTTTGATAACTTACAT
GTGTGGACAAAGCTAATAGTGGTTTTTTAAACAGCACCTTGCCTGAACATGACTTTAAAGAAATTAATATATTGAAAACATGTTTGAACC
CTTATTTTAATTGCACCATTAAAACATTTGACTTAAATTGTTTGACCATTCCAGTTGGTGTACTGTTCTGATTTTTCGTTGTGTAGGCCG
ATCTGCCTGTCAGAGTCCACGTGTCCTGGTCACTGGTCTTTATAATTGTTGTGCAATAACTAAAGGCTAAGGACTAGATGCACTATCGTG
TAAAGAGATTACACATGACTGTACCATGTTGCACTTAATCAAATAGTATGTGGGGATTTAAAATCGCTTGCATTGTTTCACAAAATAAAT
ATCTCAATGTCAAATACTAGATAAGCATCTAAGTCATTTCTACGGAATCCTGTTCAGATAGGGGCACAATAAAATGAGTACAGAGCACCG
GGGCCCTCACCTGGCAATCGCAGCTTTCATTTACTGCGTTGATCACTGCCCAGTCCTAAGGCTACAAAGCCATCCTCACTACATCCTTCA

>In-frame_ENST00000577810_ENST00000258991_TCGA-AG-3902_MIEN1_chr17_37886446_-_TEX2_chr17_62238293_length(amino acids)=299AA_start in transcript=15_stop in transcript=914
MSGEPGQTSVAPPPEEVEPGSGVRIVVEYCEPCGFEATYLELASAVKEQYPGIEIESRLGGTGLWIDLEMSYNGSFLMTLETKMNLTKLG
KEPLVEALKVGEIGKEGCRPRAFCLADSDEESSSAGSSEEDDAPEPSGGDKQLLPGAEGYVGGHRTSKIMRFVDKITKSKYFQKATETEF
IKKKIEEVSNTPLLLTVEVQECRGTLAVNIPPPPTDRVWYGFRKPPHVELKARPKLGEREVTLVHVTDWIEKKLEQEFQKVFVMPNMDDV

--------------------------------------------------------------
>In-frame_ENST00000577810_ENST00000583097_TCGA-AG-3902_MIEN1_chr17_37886446_-_TEX2_chr17_62238293_length(transcript)=2210nt_BP=202nt
GCGGAGCCGGCCGCGATGAGCGGGGAGCCGGGGCAGACGTCCGTAGCGCCCCCTCCCGAGGAGGTCGAGCCGGGCAGTGGGGTCCGCATC
GTGGTGGAGTACTGTGAACCCTGCGGCTTCGAGGCGACCTACCTGGAGCTGGCCAGTGCTGTGAAGGAGCAGTATCCGGGCATCGAGATC
GAGTCGCGCCTCGGGGGCACAGGACTCTGGATTGATTTGGAAATGTCCTACAATGGGTCCTTTCTGATGACTCTCGAGACCAAAATGAAT
TTGACCAAACTAGGTAAAGAGCCTCTTGTTGAAGCCCTGAAGGTTGGAGAAATTGGCAAAGAAGGTTGCAGGCCCCGGGCATTCTGTCTG
GCGGACAGCGATGAGGAATCCTCCAGCGCTGGCTCCTCCGAGGAAGACGATGCCCCAGAGCCCAGCGGGGGAGACAAACAGCTCCTCCCA
GGGGCTGAAGGGTACGTTGGAGGTCATCGAACAAGTAAGATTATGAGGTTTGTTGATAAAATTACCAAGTCAAAATATTTCCAAAAAGCA
ACAGAGACAGAGTTTATTAAAAAGAAGATCGAAGAAGTCTCCAACACACCCCTGCTGCTCACTGTTGAAGTACAAGAATGTAGAGGAACC
TTGGCGGTCAACATTCCACCACCCCCGACTGACCGAGTATGGTATGGTTTCCGAAAGCCACCACATGTGGAGCTGAAAGCTCGGCCAAAA
CTTGGAGAGAGAGAAGTGACTTTAGTTCATGTGACAGACTGGATAGAGAAGAAACTGGAGCAAGAGTTTCAGAAAGTTTTTGTCATGCCA
AACATGGATGATGTTTATATCACTATAATGCACTCAGCCATGGACCCTCGCTCTACTTCCTGCCTCCTGAAAGACCCACCTGTGGAGGCT
GCTGATCAGCCATGATGGGTGATGTCAGATGTTCCCCATATTGTGACATCGAGCTGGATGTGTGGGGTTCTTGGCCGCCATCTGTACTGT
AGCACTGGCCTCTGTGCCACAGCTACTGTTTCTTAAAGGACTGCTTCTGCCCTCTGCCTGCCAGTGCCCATTCCACTGTGAGGTGTCATT
CCCTGCATCTAGTGACAACTGTCTGGATTGCCTGCTGCAAAGCTTTGATTTGGCAAAGGAGACCATGGAAGAATCATGGTGGATCCAGAA
GTTATACGTGACCCACACCATGGCTTTTAAAAGTCTACCCATGTTTGTGGCAGCAAATGAGCACAGTAAGAGCAAAGCTGAACAACTTGC
CTCCTCTACTCCTCCAAAGCTTTTCTTCAGGCAGCCGGTGCACAGTGGACTTTTTCACTTCTATACTTTGTATGCGGCCTTCCACACTTC
CAGAGAATGTCAGTGTGCAATGTGTCTGGAGGGTGGGGAGAGGAATTCTGTGAGCCTTTTCATTTCGGTGACAGAAGAGATGGGCAGAGC
AACTTATTTTCCACATTAAATTGTGCATTTGGGAAGCAAGTAGCCATAGTACACACACAACACGCTATCAGCTTGGGTAAGGACAGTGGG
ATTTATGTGAACATCAGGCAAAGCCATGAGATCAAACCATCCCAAGCCTTTCACCAATGAGGTACAACCACCTGGGGGCTAGCTAATCTT
GAATGTTTTCCTGAGACAGGAGCGTATGTGAAAACATCAAACACTGCACATGACAGGATGGGTCCTCTCATACAGATGGGATGGGGTTAG
AAAGCCAGAGCCAGTTTTTCCATCTGGCGTTTCCTGTGTCCTCCAGGTTTATATGGGAATCGAAACAGTTTGTTAATCTGATTGGGAGAG
TTCCATGGGCAGATTTCCCTTCCTGAAGGCCAAAACGGAGAACTGCTCTCTTTAATTATTTCAAGAGTCAAGACCAAAAGTTTGCTCAGC
ATCACACTACATCTCAAAATTAATGTTGCCAACTTAATTTTGTGCATTTGTGTCAGAATGTTTAGTTTACAAGGTTGGGGGCTCTCTTTG
CTTCGAGAAGTAAACCTAATACCATTTTTTTATTGTTTAAAGCTGCATTCAACGTCAAAATTACCTTGGGTAACTTTTGATAACTTACAT
GTGTGGACAAAGCTAATAGTGGTTTTTTAAACAGCACCTTGCCTGAACATGACTTTAAAGAAATTAATATATTGAAAACATGTTTGAACC

>In-frame_ENST00000577810_ENST00000583097_TCGA-AG-3902_MIEN1_chr17_37886446_-_TEX2_chr17_62238293_length(amino acids)=299AA_start in transcript=15_stop in transcript=914
MSGEPGQTSVAPPPEEVEPGSGVRIVVEYCEPCGFEATYLELASAVKEQYPGIEIESRLGGTGLWIDLEMSYNGSFLMTLETKMNLTKLG
KEPLVEALKVGEIGKEGCRPRAFCLADSDEESSSAGSSEEDDAPEPSGGDKQLLPGAEGYVGGHRTSKIMRFVDKITKSKYFQKATETEF
IKKKIEEVSNTPLLLTVEVQECRGTLAVNIPPPPTDRVWYGFRKPPHVELKARPKLGEREVTLVHVTDWIEKKLEQEFQKVFVMPNMDDV

--------------------------------------------------------------
>In-frame_ENST00000577810_ENST00000584379_TCGA-AG-3902_MIEN1_chr17_37886446_-_TEX2_chr17_62238293_length(transcript)=2197nt_BP=202nt
GCGGAGCCGGCCGCGATGAGCGGGGAGCCGGGGCAGACGTCCGTAGCGCCCCCTCCCGAGGAGGTCGAGCCGGGCAGTGGGGTCCGCATC
GTGGTGGAGTACTGTGAACCCTGCGGCTTCGAGGCGACCTACCTGGAGCTGGCCAGTGCTGTGAAGGAGCAGTATCCGGGCATCGAGATC
GAGTCGCGCCTCGGGGGCACAGGACTCTGGATTGATTTGGAAATGTCCTACAATGGGTCCTTTCTGATGACTCTCGAGACCAAAATGAAT
TTGACCAAACTAGGTAAAGAGCCTCTTGTTGAAGCCCTGAAGGTTGGAGAAATTGGCAAAGAAGGTTGCAGGCCCCGGGCATTCTGTCTG
GCGGACAGCGATGAGGAATCCTCCAGCGCTGGCTCCTCCGAGGAAGACGATGCCCCAGAGCCCAGCGGGGGAGACAAACAGCTCCTCCCA
GGGGCTGAAGGGTACGTTGGAGGTCATCGAACAAGTAAGATTATGAGGTTTGTTGATAAAATTACCAAGTCAAAATATTTCCAAAAAGCA
ACAGAGACAGAGTTTATTAAAAAGAAGATCGAAGAAGTCTCCAACACACCCCTGCTGCTCACTGTTGAAGTACAAGAATGTAGAGGAACC
TTGGCGGTCAACATTCCACCACCCCCGACTGACCGAGTATGGTATGGTTTCCGAAAGCCACCACATGTGGAGCTGAAAGCTCGGCCAAAA
CTTGGAGAGAGAGAAGTGACTTTAGTTCATGTGACAGACTGGATAGAGAAGAAACTGGAGCAAGAGTTTCAGAAAGTTTTTGTCATGCCA
AACATGGATGATGTTTATATCACTATAATGCACTCAGCCATGGACCCTCGCTCTACTTCCTGCCTCCTGAAAGACCCACCTGTGGAGGCT
GCTGATCAGCCATGATGGGTGATGTCAGATGTTCCCCATATTGTGACATCGAGCTGGATGTGTGGGGTTCTTGGCCGCCATCTGTACTGT
AGCACTGGCCTCTGTGCCACAGCTACTGTTTCTTAAAGGACTGCTTCTGCCCTCTGCCTGCCAGTGCCCATTCCACTGTGAGGTGTCATT
CCCTGCATCTAGTGACAACTGTCTGGATTGCCTGCTGCAAAGCTTTGATTTGGCAAAGGAGACCATGGAAGAATCATGGTGGATCCAGAA
GTTATACGTGACCCACACCATGGCTTTTAAAAGTCTACCCATGTTTGTGGCAGCAAATGAGCACAGTAAGAGCAAAGCTGAACAACTTGC
CTCCTCTACTCCTCCAAAGCTTTTCTTCAGGCAGCCGGTGCACAGTGGACTTTTTCACTTCTATACTTTGTATGCGGCCTTCCACACTTC
CAGAGAATGTCAGTGTGCAATGTGTCTGGAGGGTGGGGAGAGGAATTCTGTGAGCCTTTTCATTTCGGTGACAGAAGAGATGGGCAGAGC
AACTTATTTTCCACATTAAATTGTGCATTTGGGAAGCAAGTAGCCATAGTACACACACAACACGCTATCAGCTTGGGTAAGGACAGTGGG
ATTTATGTGAACATCAGGCAAAGCCATGAGATCAAACCATCCCAAGCCTTTCACCAATGAGGTACAACCACCTGGGGGCTAGCTAATCTT
GAATGTTTTCCTGAGACAGGAGCGTATGTGAAAACATCAAACACTGCACATGACAGGATGGGTCCTCTCATACAGATGGGATGGGGTTAG
AAAGCCAGAGCCAGTTTTTCCATCTGGCGTTTCCTGTGTCCTCCAGGTTTATATGGGAATCGAAACAGTTTGTTAATCTGATTGGGAGAG
TTCCATGGGCAGATTTCCCTTCCTGAAGGCCAAAACGGAGAACTGCTCTCTTTAATTATTTCAAGAGTCAAGACCAAAAGTTTGCTCAGC
ATCACACTACATCTCAAAATTAATGTTGCCAACTTAATTTTGTGCATTTGTGTCAGAATGTTTAGTTTACAAGGTTGGGGGCTCTCTTTG
CTTCGAGAAGTAAACCTAATACCATTTTTTTATTGTTTAAAGCTGCATTCAACGTCAAAATTACCTTGGGTAACTTTTGATAACTTACAT
GTGTGGACAAAGCTAATAGTGGTTTTTTAAACAGCACCTTGCCTGAACATGACTTTAAAGAAATTAATATATTGAAAACATGTTTGAACC

>In-frame_ENST00000577810_ENST00000584379_TCGA-AG-3902_MIEN1_chr17_37886446_-_TEX2_chr17_62238293_length(amino acids)=299AA_start in transcript=15_stop in transcript=914
MSGEPGQTSVAPPPEEVEPGSGVRIVVEYCEPCGFEATYLELASAVKEQYPGIEIESRLGGTGLWIDLEMSYNGSFLMTLETKMNLTKLG
KEPLVEALKVGEIGKEGCRPRAFCLADSDEESSSAGSSEEDDAPEPSGGDKQLLPGAEGYVGGHRTSKIMRFVDKITKSKYFQKATETEF
IKKKIEEVSNTPLLLTVEVQECRGTLAVNIPPPPTDRVWYGFRKPPHVELKARPKLGEREVTLVHVTDWIEKKLEQEFQKVFVMPNMDDV

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Fusion Gene PPI Analysis for MIEN1-TEX2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for MIEN1-TEX2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for MIEN1-TEX2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource