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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:MPRIP-RAF1 (FusionGDB2 ID:54462) |
Fusion Gene Summary for MPRIP-RAF1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: MPRIP-RAF1 | Fusion gene ID: 54462 | Hgene | Tgene | Gene symbol | MPRIP | RAF1 | Gene ID | 23164 | 6037 |
| Gene name | myosin phosphatase Rho interacting protein | ribonuclease A family member 3 | |
| Synonyms | M-RIP|MRIP|RHOIP3|RIP3|p116Rip | ECP|RAF1|RNS3 | |
| Cytomap | 17p11.2 | 14q11.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | myosin phosphatase Rho-interacting proteinRho interacting protein 3 | eosinophil cationic proteinRNase 3cytotoxic ribonucleaseribonuclease 3ribonuclease, RNase A family, 3 | |
| Modification date | 20200313 | 20200313 | |
| UniProtAcc | Q6WCQ1 | P04049 | |
| Ensembl transtripts involved in fusion gene | ENST00000395811, ENST00000444976, ENST00000395804, ENST00000341712, ENST00000395806, ENST00000395807, | ENST00000251849, ENST00000442415, ENST00000534997, ENST00000542177, | |
| Fusion gene scores | * DoF score | 24 X 12 X 11=3168 | 19 X 16 X 7=2128 |
| # samples | 23 | 18 | |
| ** MAII score | log2(23/3168*10)=-3.78386656913523 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(18/2128*10)=-3.56342933917152 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: MPRIP [Title/Abstract] AND RAF1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | MPRIP(17083402)-RAF1(12641914), # samples:1 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | RAF1 | GO:0002227 | innate immune response in mucosa | 12860195 |
| Tgene | RAF1 | GO:0019731 | antibacterial humoral response | 12860195 |
| Tgene | RAF1 | GO:0043152 | induction of bacterial agglutination | 23992292 |
| Tgene | RAF1 | GO:0045087 | innate immune response | 23992292 |
| Tgene | RAF1 | GO:0050829 | defense response to Gram-negative bacterium | 23992292 |
| Tgene | RAF1 | GO:0050830 | defense response to Gram-positive bacterium | 12860195|23992292 |
| Tgene | RAF1 | GO:0061844 | antimicrobial humoral immune response mediated by antimicrobial peptide | 12860195 |
| Fusion gene breakpoints across MPRIP (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
| Fusion gene breakpoints across RAF1 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | SKCM | TCGA-D9-A4Z6-06A | MPRIP | chr17 | 17083402 | + | RAF1 | chr3 | 12641914 | - |
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Fusion Gene ORF analysis for MPRIP-RAF1 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000395811 | ENST00000251849 | MPRIP | chr17 | 17083402 | + | RAF1 | chr3 | 12641914 | - |
| In-frame | ENST00000395811 | ENST00000442415 | MPRIP | chr17 | 17083402 | + | RAF1 | chr3 | 12641914 | - |
| In-frame | ENST00000395811 | ENST00000534997 | MPRIP | chr17 | 17083402 | + | RAF1 | chr3 | 12641914 | - |
| In-frame | ENST00000395811 | ENST00000542177 | MPRIP | chr17 | 17083402 | + | RAF1 | chr3 | 12641914 | - |
| In-frame | ENST00000444976 | ENST00000251849 | MPRIP | chr17 | 17083402 | + | RAF1 | chr3 | 12641914 | - |
| In-frame | ENST00000444976 | ENST00000442415 | MPRIP | chr17 | 17083402 | + | RAF1 | chr3 | 12641914 | - |
| In-frame | ENST00000444976 | ENST00000534997 | MPRIP | chr17 | 17083402 | + | RAF1 | chr3 | 12641914 | - |
| In-frame | ENST00000444976 | ENST00000542177 | MPRIP | chr17 | 17083402 | + | RAF1 | chr3 | 12641914 | - |
| In-frame | ENST00000395804 | ENST00000251849 | MPRIP | chr17 | 17083402 | + | RAF1 | chr3 | 12641914 | - |
| In-frame | ENST00000395804 | ENST00000442415 | MPRIP | chr17 | 17083402 | + | RAF1 | chr3 | 12641914 | - |
| In-frame | ENST00000395804 | ENST00000534997 | MPRIP | chr17 | 17083402 | + | RAF1 | chr3 | 12641914 | - |
| In-frame | ENST00000395804 | ENST00000542177 | MPRIP | chr17 | 17083402 | + | RAF1 | chr3 | 12641914 | - |
| In-frame | ENST00000341712 | ENST00000251849 | MPRIP | chr17 | 17083402 | + | RAF1 | chr3 | 12641914 | - |
| In-frame | ENST00000341712 | ENST00000442415 | MPRIP | chr17 | 17083402 | + | RAF1 | chr3 | 12641914 | - |
| In-frame | ENST00000341712 | ENST00000534997 | MPRIP | chr17 | 17083402 | + | RAF1 | chr3 | 12641914 | - |
| In-frame | ENST00000341712 | ENST00000542177 | MPRIP | chr17 | 17083402 | + | RAF1 | chr3 | 12641914 | - |
| intron-3CDS | ENST00000395806 | ENST00000251849 | MPRIP | chr17 | 17083402 | + | RAF1 | chr3 | 12641914 | - |
| intron-3CDS | ENST00000395806 | ENST00000442415 | MPRIP | chr17 | 17083402 | + | RAF1 | chr3 | 12641914 | - |
| intron-3CDS | ENST00000395806 | ENST00000534997 | MPRIP | chr17 | 17083402 | + | RAF1 | chr3 | 12641914 | - |
| intron-3CDS | ENST00000395806 | ENST00000542177 | MPRIP | chr17 | 17083402 | + | RAF1 | chr3 | 12641914 | - |
| intron-3CDS | ENST00000395807 | ENST00000251849 | MPRIP | chr17 | 17083402 | + | RAF1 | chr3 | 12641914 | - |
| intron-3CDS | ENST00000395807 | ENST00000442415 | MPRIP | chr17 | 17083402 | + | RAF1 | chr3 | 12641914 | - |
| intron-3CDS | ENST00000395807 | ENST00000534997 | MPRIP | chr17 | 17083402 | + | RAF1 | chr3 | 12641914 | - |
| intron-3CDS | ENST00000395807 | ENST00000542177 | MPRIP | chr17 | 17083402 | + | RAF1 | chr3 | 12641914 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000395811 | MPRIP | chr17 | 17083402 | + | ENST00000251849 | RAF1 | chr3 | 12641914 | - | 5160 | 3134 | 89 | 4246 | 1385 |
| ENST00000395811 | MPRIP | chr17 | 17083402 | + | ENST00000442415 | RAF1 | chr3 | 12641914 | - | 4963 | 3134 | 89 | 4246 | 1385 |
| ENST00000395811 | MPRIP | chr17 | 17083402 | + | ENST00000534997 | RAF1 | chr3 | 12641914 | - | 4494 | 3134 | 89 | 4246 | 1385 |
| ENST00000395811 | MPRIP | chr17 | 17083402 | + | ENST00000542177 | RAF1 | chr3 | 12641914 | - | 4428 | 3134 | 89 | 4246 | 1385 |
| ENST00000444976 | MPRIP | chr17 | 17083402 | + | ENST00000251849 | RAF1 | chr3 | 12641914 | - | 5037 | 3011 | 80 | 4123 | 1347 |
| ENST00000444976 | MPRIP | chr17 | 17083402 | + | ENST00000442415 | RAF1 | chr3 | 12641914 | - | 4840 | 3011 | 80 | 4123 | 1347 |
| ENST00000444976 | MPRIP | chr17 | 17083402 | + | ENST00000534997 | RAF1 | chr3 | 12641914 | - | 4371 | 3011 | 80 | 4123 | 1347 |
| ENST00000444976 | MPRIP | chr17 | 17083402 | + | ENST00000542177 | RAF1 | chr3 | 12641914 | - | 4305 | 3011 | 80 | 4123 | 1347 |
| ENST00000395804 | MPRIP | chr17 | 17083402 | + | ENST00000251849 | RAF1 | chr3 | 12641914 | - | 5127 | 3101 | 56 | 4213 | 1385 |
| ENST00000395804 | MPRIP | chr17 | 17083402 | + | ENST00000442415 | RAF1 | chr3 | 12641914 | - | 4930 | 3101 | 56 | 4213 | 1385 |
| ENST00000395804 | MPRIP | chr17 | 17083402 | + | ENST00000534997 | RAF1 | chr3 | 12641914 | - | 4461 | 3101 | 56 | 4213 | 1385 |
| ENST00000395804 | MPRIP | chr17 | 17083402 | + | ENST00000542177 | RAF1 | chr3 | 12641914 | - | 4395 | 3101 | 56 | 4213 | 1385 |
| ENST00000341712 | MPRIP | chr17 | 17083402 | + | ENST00000251849 | RAF1 | chr3 | 12641914 | - | 5071 | 3045 | 0 | 4157 | 1385 |
| ENST00000341712 | MPRIP | chr17 | 17083402 | + | ENST00000442415 | RAF1 | chr3 | 12641914 | - | 4874 | 3045 | 0 | 4157 | 1385 |
| ENST00000341712 | MPRIP | chr17 | 17083402 | + | ENST00000534997 | RAF1 | chr3 | 12641914 | - | 4405 | 3045 | 0 | 4157 | 1385 |
| ENST00000341712 | MPRIP | chr17 | 17083402 | + | ENST00000542177 | RAF1 | chr3 | 12641914 | - | 4339 | 3045 | 0 | 4157 | 1385 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000395811 | ENST00000251849 | MPRIP | chr17 | 17083402 | + | RAF1 | chr3 | 12641914 | - | 0.009076027 | 0.99092394 |
| ENST00000395811 | ENST00000442415 | MPRIP | chr17 | 17083402 | + | RAF1 | chr3 | 12641914 | - | 0.011562008 | 0.98843795 |
| ENST00000395811 | ENST00000534997 | MPRIP | chr17 | 17083402 | + | RAF1 | chr3 | 12641914 | - | 0.012484508 | 0.98751545 |
| ENST00000395811 | ENST00000542177 | MPRIP | chr17 | 17083402 | + | RAF1 | chr3 | 12641914 | - | 0.013044324 | 0.98695564 |
| ENST00000444976 | ENST00000251849 | MPRIP | chr17 | 17083402 | + | RAF1 | chr3 | 12641914 | - | 0.009624095 | 0.99037594 |
| ENST00000444976 | ENST00000442415 | MPRIP | chr17 | 17083402 | + | RAF1 | chr3 | 12641914 | - | 0.012270322 | 0.9877296 |
| ENST00000444976 | ENST00000534997 | MPRIP | chr17 | 17083402 | + | RAF1 | chr3 | 12641914 | - | 0.013205302 | 0.98679477 |
| ENST00000444976 | ENST00000542177 | MPRIP | chr17 | 17083402 | + | RAF1 | chr3 | 12641914 | - | 0.013655108 | 0.98634493 |
| ENST00000395804 | ENST00000251849 | MPRIP | chr17 | 17083402 | + | RAF1 | chr3 | 12641914 | - | 0.008949223 | 0.99105084 |
| ENST00000395804 | ENST00000442415 | MPRIP | chr17 | 17083402 | + | RAF1 | chr3 | 12641914 | - | 0.011433771 | 0.9885662 |
| ENST00000395804 | ENST00000534997 | MPRIP | chr17 | 17083402 | + | RAF1 | chr3 | 12641914 | - | 0.012312668 | 0.9876873 |
| ENST00000395804 | ENST00000542177 | MPRIP | chr17 | 17083402 | + | RAF1 | chr3 | 12641914 | - | 0.01283897 | 0.98716104 |
| ENST00000341712 | ENST00000251849 | MPRIP | chr17 | 17083402 | + | RAF1 | chr3 | 12641914 | - | 0.008102889 | 0.99189717 |
| ENST00000341712 | ENST00000442415 | MPRIP | chr17 | 17083402 | + | RAF1 | chr3 | 12641914 | - | 0.010638906 | 0.9893611 |
| ENST00000341712 | ENST00000534997 | MPRIP | chr17 | 17083402 | + | RAF1 | chr3 | 12641914 | - | 0.01131096 | 0.988689 |
| ENST00000341712 | ENST00000542177 | MPRIP | chr17 | 17083402 | + | RAF1 | chr3 | 12641914 | - | 0.011771889 | 0.98822814 |
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Fusion Genomic Features for MPRIP-RAF1 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for MPRIP-RAF1 |
| Go to FGviewer for the breakpoints of chr17:17083402-chr3:12641914 - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| MPRIP | RAF1 |
| FUNCTION: Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells. {ECO:0000250|UniProtKB:P97434, ECO:0000269|PubMed:15545284, ECO:0000269|PubMed:16257966}. | FUNCTION: Serine/threonine-protein kinase that acts as a regulatory link between the membrane-associated Ras GTPases and the MAPK/ERK cascade, and this critical regulatory link functions as a switch determining cell fate decisions including proliferation, differentiation, apoptosis, survival and oncogenic transformation. RAF1 activation initiates a mitogen-activated protein kinase (MAPK) cascade that comprises a sequential phosphorylation of the dual-specific MAPK kinases (MAP2K1/MEK1 and MAP2K2/MEK2) and the extracellular signal-regulated kinases (MAPK3/ERK1 and MAPK1/ERK2). The phosphorylated form of RAF1 (on residues Ser-338 and Ser-339, by PAK1) phosphorylates BAD/Bcl2-antagonist of cell death at 'Ser-75'. Phosphorylates adenylyl cyclases: ADCY2, ADCY5 and ADCY6, resulting in their activation. Phosphorylates PPP1R12A resulting in inhibition of the phosphatase activity. Phosphorylates TNNT2/cardiac muscle troponin T. Can promote NF-kB activation and inhibit signal transducers involved in motility (ROCK2), apoptosis (MAP3K5/ASK1 and STK3/MST2), proliferation and angiogenesis (RB1). Can protect cells from apoptosis also by translocating to the mitochondria where it binds BCL2 and displaces BAD/Bcl2-antagonist of cell death. Regulates Rho signaling and migration, and is required for normal wound healing. Plays a role in the oncogenic transformation of epithelial cells via repression of the TJ protein, occludin (OCLN) by inducing the up-regulation of a transcriptional repressor SNAI2/SLUG, which induces down-regulation of OCLN. Restricts caspase activation in response to selected stimuli, notably Fas stimulation, pathogen-mediated macrophage apoptosis, and erythroid differentiation. {ECO:0000269|PubMed:11427728, ECO:0000269|PubMed:11719507, ECO:0000269|PubMed:15385642, ECO:0000269|PubMed:15618521, ECO:0000269|PubMed:15849194, ECO:0000269|PubMed:16892053, ECO:0000269|PubMed:16924233, ECO:0000269|PubMed:9360956}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | MPRIP | chr17:17083402 | chr3:12641914 | ENST00000341712 | + | 22 | 24 | 673_977 | 1015.0 | 1231.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | MPRIP | chr17:17083402 | chr3:12641914 | ENST00000395804 | + | 22 | 23 | 673_977 | 1015.0 | 1026.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | MPRIP | chr17:17083402 | chr3:12641914 | ENST00000395811 | + | 22 | 23 | 673_977 | 1015.0 | 1039.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | MPRIP | chr17:17083402 | chr3:12641914 | ENST00000444976 | + | 21 | 22 | 673_977 | 977.0 | 1001.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | MPRIP | chr17:17083402 | chr3:12641914 | ENST00000341712 | + | 22 | 24 | 179_252 | 1015.0 | 1231.0 | Compositional bias | Note=Ser-rich |
| Hgene | MPRIP | chr17:17083402 | chr3:12641914 | ENST00000395804 | + | 22 | 23 | 179_252 | 1015.0 | 1026.0 | Compositional bias | Note=Ser-rich |
| Hgene | MPRIP | chr17:17083402 | chr3:12641914 | ENST00000395811 | + | 22 | 23 | 179_252 | 1015.0 | 1039.0 | Compositional bias | Note=Ser-rich |
| Hgene | MPRIP | chr17:17083402 | chr3:12641914 | ENST00000444976 | + | 21 | 22 | 179_252 | 977.0 | 1001.0 | Compositional bias | Note=Ser-rich |
| Hgene | MPRIP | chr17:17083402 | chr3:12641914 | ENST00000341712 | + | 22 | 24 | 387_483 | 1015.0 | 1231.0 | Domain | PH 2 |
| Hgene | MPRIP | chr17:17083402 | chr3:12641914 | ENST00000341712 | + | 22 | 24 | 43_150 | 1015.0 | 1231.0 | Domain | PH 1 |
| Hgene | MPRIP | chr17:17083402 | chr3:12641914 | ENST00000395804 | + | 22 | 23 | 387_483 | 1015.0 | 1026.0 | Domain | PH 2 |
| Hgene | MPRIP | chr17:17083402 | chr3:12641914 | ENST00000395804 | + | 22 | 23 | 43_150 | 1015.0 | 1026.0 | Domain | PH 1 |
| Hgene | MPRIP | chr17:17083402 | chr3:12641914 | ENST00000395811 | + | 22 | 23 | 387_483 | 1015.0 | 1039.0 | Domain | PH 2 |
| Hgene | MPRIP | chr17:17083402 | chr3:12641914 | ENST00000395811 | + | 22 | 23 | 43_150 | 1015.0 | 1039.0 | Domain | PH 1 |
| Hgene | MPRIP | chr17:17083402 | chr3:12641914 | ENST00000444976 | + | 21 | 22 | 387_483 | 977.0 | 1001.0 | Domain | PH 2 |
| Hgene | MPRIP | chr17:17083402 | chr3:12641914 | ENST00000444976 | + | 21 | 22 | 43_150 | 977.0 | 1001.0 | Domain | PH 1 |
| Tgene | RAF1 | chr17:17083402 | chr3:12641914 | ENST00000251849 | 6 | 17 | 349_609 | 278.0 | 649.0 | Domain | Protein kinase | |
| Tgene | RAF1 | chr17:17083402 | chr3:12641914 | ENST00000442415 | 7 | 18 | 349_609 | 298.0 | 669.0 | Domain | Protein kinase | |
| Tgene | RAF1 | chr17:17083402 | chr3:12641914 | ENST00000251849 | 6 | 17 | 355_363 | 278.0 | 649.0 | Nucleotide binding | ATP | |
| Tgene | RAF1 | chr17:17083402 | chr3:12641914 | ENST00000442415 | 7 | 18 | 355_363 | 298.0 | 669.0 | Nucleotide binding | ATP |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | RAF1 | chr17:17083402 | chr3:12641914 | ENST00000251849 | 6 | 17 | 56_131 | 278.0 | 649.0 | Domain | RBD | |
| Tgene | RAF1 | chr17:17083402 | chr3:12641914 | ENST00000442415 | 7 | 18 | 56_131 | 298.0 | 669.0 | Domain | RBD | |
| Tgene | RAF1 | chr17:17083402 | chr3:12641914 | ENST00000251849 | 6 | 17 | 138_184 | 278.0 | 649.0 | Zinc finger | Phorbol-ester/DAG-type | |
| Tgene | RAF1 | chr17:17083402 | chr3:12641914 | ENST00000442415 | 7 | 18 | 138_184 | 298.0 | 669.0 | Zinc finger | Phorbol-ester/DAG-type |
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Fusion Gene Sequence for MPRIP-RAF1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >In-frame_ENST00000395811_ENST00000251849_TCGA-D9-A4Z6-06A_MPRIP_chr17_17083402_+_RAF1_chr3_12641914_length(transcript)=5160nt_BP=3134nt GCGGCCGCGCTGAGCCCCTAGCCCGCCGGGAGCGCCAGGCCGGCCAGGCCTGCGCCGCCGCCGCCGCCGCCGTCGCCGCCGCGCCGACCA TGTCGGCAGCCAAGGAGAACCCGTGCAGGAAATTCCAGGCCAACATCTTCAACAAGAGCAAGTGTCAGAACTGCTTCAAGCCCCGCGAGT CGCATCTGCTCAACGACGAGGACCTGACGCAGGCAAAACCCATTTATGGCGGTTGGCTGCTCCTGGCTCCAGATGGGACCGACTTTGACA ACCCAGTGCACCGGTCTCGGAAATGGCAGCGACGGTTCTTCATCCTTTACGAGCACGGCCTCTTGCGCTACGCCCTGGATGAGATGCCCA CGACCCTTCCTCAGGGCACCATCAACATGAACCAGTGCACAGATGTGGTGGATGGGGAGGGCCGCACGGGCCAGAAGTTCTCCCTGTGTA TTCTGACGCCTGAGAAGGAGCATTTCATCCGGGCGGAGACCAAGGAGATCGTCAGTGGGTGGCTGGAGATGCTCATGGTCTATCCCCGGA CCAACAAGCAGAATCAGAAGAAGAAACGGAAAGTGGAGCCCCCCACACCACAGGAGCCTGGGCCTGCCAAGGTGGCTGTTACCAGCAGCA GCAGCAGCAGCAGCAGCAGCAGCAGCATCCCCAGTGCTGAGAAAGTCCCCACCACCAAGTCCACACTCTGGCAGGAAGAAATGAGGACCA AGGACCAGCCAGATGGCAGCAGCCTGAGTCCAGCTCAGAGTCCCAGCCAGAGCCAGCCTCCTGCTGCCAGCTCCCTGCGGGAACCTGGGC TAGAGAGCAAAGAAGAGGAGAGCGCCATGAGTAGCGACCGCATGGACTGTGGCCGCAAAGTCCGGGTGGAGAGCGGCTACTTCTCTCTGG AGAAGACCAAACAGGACTTGAAGGCTGAAGAACAGCAGCTGCCCCCGCCGCTCTCCCCTCCCAGCCCCAGCACCCCCAACCACAGGAGGT CCCAGGTGATTGAAAAGTTTGAGGCCTTGGACATTGAGAAGGCAGAGCACATGGAGACCAATGCAGTGGGGCCCTCACCATCCAGCGACA CACGCCAGGGCCGCAGCGAGAAGAGGGCGTTCCCTAGGAAGCGGGACTTCACCAATGAAGCCCCCCCAGCTCCTCTCCCAGACGCCTCGG CTTCCCCCCTGTCTCCACACCGAAGAGCCAAGTCACTGGACAGGAGGTCCACGGAGCCCTCCGTGACGCCCGACCTGCTGAATTTCAAGA AAGGCTGGCTGACTAAGCAGTATGAGGACGGCCAGTGGAAGAAACACTGGTTTGTCCTCGCCGATCAAAGCCTGAGATACTACAGGGATT CAGTGGCTGAGGAGGCAGCCGACTTGGATGGAGAAATTGACTTGTCCGCATGTTACGATGTCACAGAGTATCCAGTTCAGAGAAACTATG GCTTCCAGATACATACAAAGGAGGGCGAGTTTACCCTGTCGGCCATGACATCTGGGATTCGGCGGAACTGGATCCAGACCATCATGAAGC ACGTGCACCCGACCACTGCCCCGGATGTGACCAGCTCGTTGCCAGAGGAAAAAAACAAGAGCAGCTGCTCTTTTGAGACCTGCCCGAGGC CTACTGAGAAGCAAGAGGCAGAGCTGGGGGAGCCGGACCCTGAGCAGAAGAGGAGCCGCGCACGGGAGCGGAGGCGAGAGGGCCGCTCCA AGACCTTTGACTGGGCTGAGTTCCGTCCCATCCAGCAGGCCCTGGCTCAGGAGCGGGTGGGCGGCGTGGGGCCTGCTGACACCCACGAGC CCCTGCGCCCTGAGGCGGAGCCTGGGGAGCTGGAGCGGGAGCGTGCACGGAGGCGGGAGGAGCGCCGCAAGCGCTTCGGGATGCTCGACG CCACAGACGGGCCAGGCACTGAGGATGCAGCCCTGCGCATGGAGGTGGACCGGAGCCCAGGGCTGCCTATGAGCGACCTCAAAACGCATA ACGTCCACGTGGAGATTGAGCAGCGGTGGCATCAGGTGGAGACCACACCTCTCCGGGAAGAGAAGCAGGTGCCCATCGCCCCCGTCCACC TGTCTTCTGAAGATGGGGGTGACCGGCTCTCCACACACGAGCTGACCTCTCTGCTCGAGAAGGAGCTGGAGCAGAGCCAGAAGGAGGCCT CAGACCTTCTGGAGCAGAACCGGCTCCTGCAGGACCAGCTGAGGGTGGCCCTGGGCCGGGAGCAGAGCGCCCGTGAGGGCTACGTGCTGC AGGCCACGTGCGAGCGAGGGTTTGCAGCAATGGAAGAAACGCACCAGAAGAAGATTGAAGATCTCCAGAGGCAGCACCAGCGGGAGCTAG AGAAACTTCGAGAAGAGAAAGACCGCCTCCTAGCCGAGGAGACAGCGGCCACCATCTCAGCCATCGAAGCCATGAAGAACGCCCACCGGG AGGAAATGGAGCGGGAGCTGGAGAAGAGCCAGCGGTCCCAGATCAGCAGCGTCAACTCGGATGTTGAGGCCCTGCGGCGCCAGTACCTGG AGGAGCTGCAGTCGGTGCAGCGGGAACTGGAGGTCCTCTCGGAGCAGTACTCGCAGAAGTGCCTGGAGAATGCCCATCTGGCCCAGGCGC TGGAGGCCGAGCGGCAGGCCCTGCGGCAGTGCCAGCGTGAGAACCAGGAGCTCAATGCCCACAACCAGGAGCTGAACAACCGCCTGGCTG CAGAGATCACACGGTTGCGGACGCTGCTGACTGGGGACGGCGGTGGGGAGGCCACTGGGTCACCCCTTGCACAGGGCAAGGATGCCTATG AACTAGAGGTCTTATTGCGGGTAAAGGAATCGGAAATACAGTACCTGAAACAGGAGATTAGCTCCCTCAAGGATGAGCTGCAGACGGCAC TGCGGGACAAGAAGTACGCAAGTGACAAGTACAAAGACATCTACACAGAGCTCAGCATCGCGAAGGCTAAGGCTGACTGTGACATCAGCA GGTTGAAGGAGCAGCTCAAGGCTGCAACGGAAGCACTGGGGGAGAAGTCCCCTGACAGTGCCACGGTGTCCGGATATGATATAATGAAAT CTAAAAGCAACCCTGACTTCTTGAAGAAAGACAGATCCTGTGTCACCCGGCAACTCAGAAACATCAGGTCCAAGGATGCAATTCGAAGTC ACAGCGAATCAGCCTCACCTTCAGCCCTGTCCAGTAGCCCCAACAATCTGAGCCCAACAGGCTGGTCACAGCCGAAAACCCCCGTGCCAG CACAAAGAGAGCGGGCACCAGTATCTGGGACCCAGGAGAAAAACAAAATTAGGCCTCGTGGACAGAGAGATTCAAGCTATTATTGGGAAA TAGAAGCCAGTGAAGTGATGCTGTCCACTCGGATTGGGTCAGGCTCTTTTGGAACTGTTTATAAGGGTAAATGGCACGGAGATGTTGCAG TAAAGATCCTAAAGGTTGTCGACCCAACCCCAGAGCAATTCCAGGCCTTCAGGAATGAGGTGGCTGTTCTGCGCAAAACACGGCATGTGA ACATTCTGCTTTTCATGGGGTACATGACAAAGGACAACCTGGCAATTGTGACCCAGTGGTGCGAGGGCAGCAGCCTCTACAAACACCTGC ATGTCCAGGAGACCAAGTTTCAGATGTTCCAGCTAATTGACATTGCCCGGCAGACGGCTCAGGGAATGGACTATTTGCATGCAAAGAACA TCATCCATAGAGACATGAAATCCAACAATATATTTCTCCATGAAGGCTTAACAGTGAAAATTGGAGATTTTGGTTTGGCAACAGTAAAGT CACGCTGGAGTGGTTCTCAGCAGGTTGAACAACCTACTGGCTCTGTCCTCTGGATGGCCCCAGAGGTGATCCGAATGCAGGATAACAACC CATTCAGTTTCCAGTCGGATGTCTACTCCTATGGCATCGTATTGTATGAACTGATGACGGGGGAGCTTCCTTATTCTCACATCAACAACC GAGATCAGATCATCTTCATGGTGGGCCGAGGATATGCCTCCCCAGATCTTAGTAAGCTATATAAGAACTGCCCCAAAGCAATGAAGAGGC TGGTAGCTGACTGTGTGAAGAAAGTAAAGGAAGAGAGGCCTCTTTTTCCCCAGATCCTGTCTTCCATTGAGCTGCTCCAACACTCTCTAC CGAAGATCAACCGGAGCGCTTCCGAGCCATCCTTGCATCGGGCAGCCCACACTGAGGATATCAATGCTTGCACGCTGACCACGTCCCCGA GGCTGCCTGTCTTCTAGTTGACTTTGCACCTGTCTTCAGGCTGCCAGGGGAGGAGGAGAAGCCAGCAGGCACCACTTTTCTGCTCCCTTT CTCCAGAGGCAGAACACATGTTTTCAGAGAAGCTGCTGCTAAGGACCTTCTAGACTGCTCACAGGGCCTTAACTTCATGTTGCCTTCTTT TCTATCCCTTTGGGCCCTGGGAGAAGGAAGCCATTTGCAGTGCTGGTGTGTCCTGCTCCCTCCCCACATTCCCCATGCTCAAGGCCCAGC CTTCTGTAGATGCGCAAGTGGATGTTGATGGTAGTACAAAAAGCAGGGGCCCAGCCCCAGCTGTTGGCTACATGAGTATTTAGAGGAAGT AAGGTAGCAGGCAGTCCAGCCCTGATGTGGAGACACATGGGATTTTGGAAATCAGCTTCTGGAGGAATGCATGTCACAGGCGGGACTTTC TTCAGAGAGTGGTGCAGCGCCAGACATTTTGCACATAAGGCACCAAACAGCCCAGGACTGCCGAGACTCTGGCCGCCCGAAGGAGCCTGC TTTGGTACTATGGAACTTTTCTTAGGGGACACGTCCTCCTTTCACAGCTTCTAAGGTGTCCAGTGCATTGGGATGGTTTTCCAGGCAAGG CACTCGGCCAATCCGCATCTCAGCCCTCTCAGGGAGCAGTCTTCCATCATGCTGAATTTTGTCTTCCAGGAGCTGCCCCTATGGGGCGGG GCCGCAGGGCCAGCCTTGTTTCTCTAACAAACAAACAAACAAACAGCCTTGTTTCTCTAGTCACATCATGTGTATACAAGGAAGCCAGGA ATACAGGTTTTCTTGATGATTTGGGTTTTAATTTTGTTTTTATTGCACCTGACAAAATACAGTTATCTGATGGTCCCTCAATTATGTTAT >In-frame_ENST00000395811_ENST00000251849_TCGA-D9-A4Z6-06A_MPRIP_chr17_17083402_+_RAF1_chr3_12641914_length(amino acids)=1385AA_start in transcript=89_stop in transcript=4246 MSAAKENPCRKFQANIFNKSKCQNCFKPRESHLLNDEDLTQAKPIYGGWLLLAPDGTDFDNPVHRSRKWQRRFFILYEHGLLRYALDEMP TTLPQGTINMNQCTDVVDGEGRTGQKFSLCILTPEKEHFIRAETKEIVSGWLEMLMVYPRTNKQNQKKKRKVEPPTPQEPGPAKVAVTSS SSSSSSSSSIPSAEKVPTTKSTLWQEEMRTKDQPDGSSLSPAQSPSQSQPPAASSLREPGLESKEEESAMSSDRMDCGRKVRVESGYFSL EKTKQDLKAEEQQLPPPLSPPSPSTPNHRRSQVIEKFEALDIEKAEHMETNAVGPSPSSDTRQGRSEKRAFPRKRDFTNEAPPAPLPDAS ASPLSPHRRAKSLDRRSTEPSVTPDLLNFKKGWLTKQYEDGQWKKHWFVLADQSLRYYRDSVAEEAADLDGEIDLSACYDVTEYPVQRNY GFQIHTKEGEFTLSAMTSGIRRNWIQTIMKHVHPTTAPDVTSSLPEEKNKSSCSFETCPRPTEKQEAELGEPDPEQKRSRARERRREGRS KTFDWAEFRPIQQALAQERVGGVGPADTHEPLRPEAEPGELERERARRREERRKRFGMLDATDGPGTEDAALRMEVDRSPGLPMSDLKTH NVHVEIEQRWHQVETTPLREEKQVPIAPVHLSSEDGGDRLSTHELTSLLEKELEQSQKEASDLLEQNRLLQDQLRVALGREQSAREGYVL QATCERGFAAMEETHQKKIEDLQRQHQRELEKLREEKDRLLAEETAATISAIEAMKNAHREEMERELEKSQRSQISSVNSDVEALRRQYL EELQSVQRELEVLSEQYSQKCLENAHLAQALEAERQALRQCQRENQELNAHNQELNNRLAAEITRLRTLLTGDGGGEATGSPLAQGKDAY ELEVLLRVKESEIQYLKQEISSLKDELQTALRDKKYASDKYKDIYTELSIAKAKADCDISRLKEQLKAATEALGEKSPDSATVSGYDIMK SKSNPDFLKKDRSCVTRQLRNIRSKDAIRSHSESASPSALSSSPNNLSPTGWSQPKTPVPAQRERAPVSGTQEKNKIRPRGQRDSSYYWE IEASEVMLSTRIGSGSFGTVYKGKWHGDVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYMTKDNLAIVTQWCEGSSLYKHL HVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNN PFSFQSDVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCVKKVKEERPLFPQILSSIELLQHSL -------------------------------------------------------------- >In-frame_ENST00000395811_ENST00000442415_TCGA-D9-A4Z6-06A_MPRIP_chr17_17083402_+_RAF1_chr3_12641914_length(transcript)=4963nt_BP=3134nt GCGGCCGCGCTGAGCCCCTAGCCCGCCGGGAGCGCCAGGCCGGCCAGGCCTGCGCCGCCGCCGCCGCCGCCGTCGCCGCCGCGCCGACCA TGTCGGCAGCCAAGGAGAACCCGTGCAGGAAATTCCAGGCCAACATCTTCAACAAGAGCAAGTGTCAGAACTGCTTCAAGCCCCGCGAGT CGCATCTGCTCAACGACGAGGACCTGACGCAGGCAAAACCCATTTATGGCGGTTGGCTGCTCCTGGCTCCAGATGGGACCGACTTTGACA ACCCAGTGCACCGGTCTCGGAAATGGCAGCGACGGTTCTTCATCCTTTACGAGCACGGCCTCTTGCGCTACGCCCTGGATGAGATGCCCA CGACCCTTCCTCAGGGCACCATCAACATGAACCAGTGCACAGATGTGGTGGATGGGGAGGGCCGCACGGGCCAGAAGTTCTCCCTGTGTA TTCTGACGCCTGAGAAGGAGCATTTCATCCGGGCGGAGACCAAGGAGATCGTCAGTGGGTGGCTGGAGATGCTCATGGTCTATCCCCGGA CCAACAAGCAGAATCAGAAGAAGAAACGGAAAGTGGAGCCCCCCACACCACAGGAGCCTGGGCCTGCCAAGGTGGCTGTTACCAGCAGCA GCAGCAGCAGCAGCAGCAGCAGCAGCATCCCCAGTGCTGAGAAAGTCCCCACCACCAAGTCCACACTCTGGCAGGAAGAAATGAGGACCA AGGACCAGCCAGATGGCAGCAGCCTGAGTCCAGCTCAGAGTCCCAGCCAGAGCCAGCCTCCTGCTGCCAGCTCCCTGCGGGAACCTGGGC TAGAGAGCAAAGAAGAGGAGAGCGCCATGAGTAGCGACCGCATGGACTGTGGCCGCAAAGTCCGGGTGGAGAGCGGCTACTTCTCTCTGG AGAAGACCAAACAGGACTTGAAGGCTGAAGAACAGCAGCTGCCCCCGCCGCTCTCCCCTCCCAGCCCCAGCACCCCCAACCACAGGAGGT CCCAGGTGATTGAAAAGTTTGAGGCCTTGGACATTGAGAAGGCAGAGCACATGGAGACCAATGCAGTGGGGCCCTCACCATCCAGCGACA CACGCCAGGGCCGCAGCGAGAAGAGGGCGTTCCCTAGGAAGCGGGACTTCACCAATGAAGCCCCCCCAGCTCCTCTCCCAGACGCCTCGG CTTCCCCCCTGTCTCCACACCGAAGAGCCAAGTCACTGGACAGGAGGTCCACGGAGCCCTCCGTGACGCCCGACCTGCTGAATTTCAAGA AAGGCTGGCTGACTAAGCAGTATGAGGACGGCCAGTGGAAGAAACACTGGTTTGTCCTCGCCGATCAAAGCCTGAGATACTACAGGGATT CAGTGGCTGAGGAGGCAGCCGACTTGGATGGAGAAATTGACTTGTCCGCATGTTACGATGTCACAGAGTATCCAGTTCAGAGAAACTATG GCTTCCAGATACATACAAAGGAGGGCGAGTTTACCCTGTCGGCCATGACATCTGGGATTCGGCGGAACTGGATCCAGACCATCATGAAGC ACGTGCACCCGACCACTGCCCCGGATGTGACCAGCTCGTTGCCAGAGGAAAAAAACAAGAGCAGCTGCTCTTTTGAGACCTGCCCGAGGC CTACTGAGAAGCAAGAGGCAGAGCTGGGGGAGCCGGACCCTGAGCAGAAGAGGAGCCGCGCACGGGAGCGGAGGCGAGAGGGCCGCTCCA AGACCTTTGACTGGGCTGAGTTCCGTCCCATCCAGCAGGCCCTGGCTCAGGAGCGGGTGGGCGGCGTGGGGCCTGCTGACACCCACGAGC CCCTGCGCCCTGAGGCGGAGCCTGGGGAGCTGGAGCGGGAGCGTGCACGGAGGCGGGAGGAGCGCCGCAAGCGCTTCGGGATGCTCGACG CCACAGACGGGCCAGGCACTGAGGATGCAGCCCTGCGCATGGAGGTGGACCGGAGCCCAGGGCTGCCTATGAGCGACCTCAAAACGCATA ACGTCCACGTGGAGATTGAGCAGCGGTGGCATCAGGTGGAGACCACACCTCTCCGGGAAGAGAAGCAGGTGCCCATCGCCCCCGTCCACC TGTCTTCTGAAGATGGGGGTGACCGGCTCTCCACACACGAGCTGACCTCTCTGCTCGAGAAGGAGCTGGAGCAGAGCCAGAAGGAGGCCT CAGACCTTCTGGAGCAGAACCGGCTCCTGCAGGACCAGCTGAGGGTGGCCCTGGGCCGGGAGCAGAGCGCCCGTGAGGGCTACGTGCTGC AGGCCACGTGCGAGCGAGGGTTTGCAGCAATGGAAGAAACGCACCAGAAGAAGATTGAAGATCTCCAGAGGCAGCACCAGCGGGAGCTAG AGAAACTTCGAGAAGAGAAAGACCGCCTCCTAGCCGAGGAGACAGCGGCCACCATCTCAGCCATCGAAGCCATGAAGAACGCCCACCGGG AGGAAATGGAGCGGGAGCTGGAGAAGAGCCAGCGGTCCCAGATCAGCAGCGTCAACTCGGATGTTGAGGCCCTGCGGCGCCAGTACCTGG AGGAGCTGCAGTCGGTGCAGCGGGAACTGGAGGTCCTCTCGGAGCAGTACTCGCAGAAGTGCCTGGAGAATGCCCATCTGGCCCAGGCGC TGGAGGCCGAGCGGCAGGCCCTGCGGCAGTGCCAGCGTGAGAACCAGGAGCTCAATGCCCACAACCAGGAGCTGAACAACCGCCTGGCTG CAGAGATCACACGGTTGCGGACGCTGCTGACTGGGGACGGCGGTGGGGAGGCCACTGGGTCACCCCTTGCACAGGGCAAGGATGCCTATG AACTAGAGGTCTTATTGCGGGTAAAGGAATCGGAAATACAGTACCTGAAACAGGAGATTAGCTCCCTCAAGGATGAGCTGCAGACGGCAC TGCGGGACAAGAAGTACGCAAGTGACAAGTACAAAGACATCTACACAGAGCTCAGCATCGCGAAGGCTAAGGCTGACTGTGACATCAGCA GGTTGAAGGAGCAGCTCAAGGCTGCAACGGAAGCACTGGGGGAGAAGTCCCCTGACAGTGCCACGGTGTCCGGATATGATATAATGAAAT CTAAAAGCAACCCTGACTTCTTGAAGAAAGACAGATCCTGTGTCACCCGGCAACTCAGAAACATCAGGTCCAAGGATGCAATTCGAAGTC ACAGCGAATCAGCCTCACCTTCAGCCCTGTCCAGTAGCCCCAACAATCTGAGCCCAACAGGCTGGTCACAGCCGAAAACCCCCGTGCCAG CACAAAGAGAGCGGGCACCAGTATCTGGGACCCAGGAGAAAAACAAAATTAGGCCTCGTGGACAGAGAGATTCAAGCTATTATTGGGAAA TAGAAGCCAGTGAAGTGATGCTGTCCACTCGGATTGGGTCAGGCTCTTTTGGAACTGTTTATAAGGGTAAATGGCACGGAGATGTTGCAG TAAAGATCCTAAAGGTTGTCGACCCAACCCCAGAGCAATTCCAGGCCTTCAGGAATGAGGTGGCTGTTCTGCGCAAAACACGGCATGTGA ACATTCTGCTTTTCATGGGGTACATGACAAAGGACAACCTGGCAATTGTGACCCAGTGGTGCGAGGGCAGCAGCCTCTACAAACACCTGC ATGTCCAGGAGACCAAGTTTCAGATGTTCCAGCTAATTGACATTGCCCGGCAGACGGCTCAGGGAATGGACTATTTGCATGCAAAGAACA TCATCCATAGAGACATGAAATCCAACAATATATTTCTCCATGAAGGCTTAACAGTGAAAATTGGAGATTTTGGTTTGGCAACAGTAAAGT CACGCTGGAGTGGTTCTCAGCAGGTTGAACAACCTACTGGCTCTGTCCTCTGGATGGCCCCAGAGGTGATCCGAATGCAGGATAACAACC CATTCAGTTTCCAGTCGGATGTCTACTCCTATGGCATCGTATTGTATGAACTGATGACGGGGGAGCTTCCTTATTCTCACATCAACAACC GAGATCAGATCATCTTCATGGTGGGCCGAGGATATGCCTCCCCAGATCTTAGTAAGCTATATAAGAACTGCCCCAAAGCAATGAAGAGGC TGGTAGCTGACTGTGTGAAGAAAGTAAAGGAAGAGAGGCCTCTTTTTCCCCAGATCCTGTCTTCCATTGAGCTGCTCCAACACTCTCTAC CGAAGATCAACCGGAGCGCTTCCGAGCCATCCTTGCATCGGGCAGCCCACACTGAGGATATCAATGCTTGCACGCTGACCACGTCCCCGA GGCTGCCTGTCTTCTAGTTGACTTTGCACCTGTCTTCAGGCTGCCAGGGGAGGAGGAGAAGCCAGCAGGCACCACTTTTCTGCTCCCTTT CTCCAGAGGCAGAACACATGTTTTCAGAGAAGCTGCTGCTAAGGACCTTCTAGACTGCTCACAGGGCCTTAACTTCATGTTGCCTTCTTT TCTATCCCTTTGGGCCCTGGGAGAAGGAAGCCATTTGCAGTGCTGGTGTGTCCTGCTCCCTCCCCACATTCCCCATGCTCAAGGCCCAGC CTTCTGTAGATGCGCAAGTGGATGTTGATGGTAGTACAAAAAGCAGGGGCCCAGCCCCAGCTGTTGGCTACATGAGTATTTAGAGGAAGT AAGGTAGCAGGCAGTCCAGCCCTGATGTGGAGACACATGGGATTTTGGAAATCAGCTTCTGGAGGAATGCATGTCACAGGCGGGACTTTC TTCAGAGAGTGGTGCAGCGCCAGACATTTTGCACATAAGGCACCAAACAGCCCAGGACTGCCGAGACTCTGGCCGCCCGAAGGAGCCTGC TTTGGTACTATGGAACTTTTCTTAGGGGACACGTCCTCCTTTCACAGCTTCTAAGGTGTCCAGTGCATTGGGATGGTTTTCCAGGCAAGG CACTCGGCCAATCCGCATCTCAGCCCTCTCAGGGAGCAGTCTTCCATCATGCTGAATTTTGTCTTCCAGGAGCTGCCCCTATGGGGCGGG >In-frame_ENST00000395811_ENST00000442415_TCGA-D9-A4Z6-06A_MPRIP_chr17_17083402_+_RAF1_chr3_12641914_length(amino acids)=1385AA_start in transcript=89_stop in transcript=4246 MSAAKENPCRKFQANIFNKSKCQNCFKPRESHLLNDEDLTQAKPIYGGWLLLAPDGTDFDNPVHRSRKWQRRFFILYEHGLLRYALDEMP TTLPQGTINMNQCTDVVDGEGRTGQKFSLCILTPEKEHFIRAETKEIVSGWLEMLMVYPRTNKQNQKKKRKVEPPTPQEPGPAKVAVTSS SSSSSSSSSIPSAEKVPTTKSTLWQEEMRTKDQPDGSSLSPAQSPSQSQPPAASSLREPGLESKEEESAMSSDRMDCGRKVRVESGYFSL EKTKQDLKAEEQQLPPPLSPPSPSTPNHRRSQVIEKFEALDIEKAEHMETNAVGPSPSSDTRQGRSEKRAFPRKRDFTNEAPPAPLPDAS ASPLSPHRRAKSLDRRSTEPSVTPDLLNFKKGWLTKQYEDGQWKKHWFVLADQSLRYYRDSVAEEAADLDGEIDLSACYDVTEYPVQRNY GFQIHTKEGEFTLSAMTSGIRRNWIQTIMKHVHPTTAPDVTSSLPEEKNKSSCSFETCPRPTEKQEAELGEPDPEQKRSRARERRREGRS KTFDWAEFRPIQQALAQERVGGVGPADTHEPLRPEAEPGELERERARRREERRKRFGMLDATDGPGTEDAALRMEVDRSPGLPMSDLKTH NVHVEIEQRWHQVETTPLREEKQVPIAPVHLSSEDGGDRLSTHELTSLLEKELEQSQKEASDLLEQNRLLQDQLRVALGREQSAREGYVL QATCERGFAAMEETHQKKIEDLQRQHQRELEKLREEKDRLLAEETAATISAIEAMKNAHREEMERELEKSQRSQISSVNSDVEALRRQYL EELQSVQRELEVLSEQYSQKCLENAHLAQALEAERQALRQCQRENQELNAHNQELNNRLAAEITRLRTLLTGDGGGEATGSPLAQGKDAY ELEVLLRVKESEIQYLKQEISSLKDELQTALRDKKYASDKYKDIYTELSIAKAKADCDISRLKEQLKAATEALGEKSPDSATVSGYDIMK SKSNPDFLKKDRSCVTRQLRNIRSKDAIRSHSESASPSALSSSPNNLSPTGWSQPKTPVPAQRERAPVSGTQEKNKIRPRGQRDSSYYWE IEASEVMLSTRIGSGSFGTVYKGKWHGDVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYMTKDNLAIVTQWCEGSSLYKHL HVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNN PFSFQSDVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCVKKVKEERPLFPQILSSIELLQHSL -------------------------------------------------------------- >In-frame_ENST00000395811_ENST00000534997_TCGA-D9-A4Z6-06A_MPRIP_chr17_17083402_+_RAF1_chr3_12641914_length(transcript)=4494nt_BP=3134nt GCGGCCGCGCTGAGCCCCTAGCCCGCCGGGAGCGCCAGGCCGGCCAGGCCTGCGCCGCCGCCGCCGCCGCCGTCGCCGCCGCGCCGACCA TGTCGGCAGCCAAGGAGAACCCGTGCAGGAAATTCCAGGCCAACATCTTCAACAAGAGCAAGTGTCAGAACTGCTTCAAGCCCCGCGAGT CGCATCTGCTCAACGACGAGGACCTGACGCAGGCAAAACCCATTTATGGCGGTTGGCTGCTCCTGGCTCCAGATGGGACCGACTTTGACA ACCCAGTGCACCGGTCTCGGAAATGGCAGCGACGGTTCTTCATCCTTTACGAGCACGGCCTCTTGCGCTACGCCCTGGATGAGATGCCCA CGACCCTTCCTCAGGGCACCATCAACATGAACCAGTGCACAGATGTGGTGGATGGGGAGGGCCGCACGGGCCAGAAGTTCTCCCTGTGTA TTCTGACGCCTGAGAAGGAGCATTTCATCCGGGCGGAGACCAAGGAGATCGTCAGTGGGTGGCTGGAGATGCTCATGGTCTATCCCCGGA CCAACAAGCAGAATCAGAAGAAGAAACGGAAAGTGGAGCCCCCCACACCACAGGAGCCTGGGCCTGCCAAGGTGGCTGTTACCAGCAGCA GCAGCAGCAGCAGCAGCAGCAGCAGCATCCCCAGTGCTGAGAAAGTCCCCACCACCAAGTCCACACTCTGGCAGGAAGAAATGAGGACCA AGGACCAGCCAGATGGCAGCAGCCTGAGTCCAGCTCAGAGTCCCAGCCAGAGCCAGCCTCCTGCTGCCAGCTCCCTGCGGGAACCTGGGC TAGAGAGCAAAGAAGAGGAGAGCGCCATGAGTAGCGACCGCATGGACTGTGGCCGCAAAGTCCGGGTGGAGAGCGGCTACTTCTCTCTGG AGAAGACCAAACAGGACTTGAAGGCTGAAGAACAGCAGCTGCCCCCGCCGCTCTCCCCTCCCAGCCCCAGCACCCCCAACCACAGGAGGT CCCAGGTGATTGAAAAGTTTGAGGCCTTGGACATTGAGAAGGCAGAGCACATGGAGACCAATGCAGTGGGGCCCTCACCATCCAGCGACA CACGCCAGGGCCGCAGCGAGAAGAGGGCGTTCCCTAGGAAGCGGGACTTCACCAATGAAGCCCCCCCAGCTCCTCTCCCAGACGCCTCGG CTTCCCCCCTGTCTCCACACCGAAGAGCCAAGTCACTGGACAGGAGGTCCACGGAGCCCTCCGTGACGCCCGACCTGCTGAATTTCAAGA AAGGCTGGCTGACTAAGCAGTATGAGGACGGCCAGTGGAAGAAACACTGGTTTGTCCTCGCCGATCAAAGCCTGAGATACTACAGGGATT CAGTGGCTGAGGAGGCAGCCGACTTGGATGGAGAAATTGACTTGTCCGCATGTTACGATGTCACAGAGTATCCAGTTCAGAGAAACTATG GCTTCCAGATACATACAAAGGAGGGCGAGTTTACCCTGTCGGCCATGACATCTGGGATTCGGCGGAACTGGATCCAGACCATCATGAAGC ACGTGCACCCGACCACTGCCCCGGATGTGACCAGCTCGTTGCCAGAGGAAAAAAACAAGAGCAGCTGCTCTTTTGAGACCTGCCCGAGGC CTACTGAGAAGCAAGAGGCAGAGCTGGGGGAGCCGGACCCTGAGCAGAAGAGGAGCCGCGCACGGGAGCGGAGGCGAGAGGGCCGCTCCA AGACCTTTGACTGGGCTGAGTTCCGTCCCATCCAGCAGGCCCTGGCTCAGGAGCGGGTGGGCGGCGTGGGGCCTGCTGACACCCACGAGC CCCTGCGCCCTGAGGCGGAGCCTGGGGAGCTGGAGCGGGAGCGTGCACGGAGGCGGGAGGAGCGCCGCAAGCGCTTCGGGATGCTCGACG CCACAGACGGGCCAGGCACTGAGGATGCAGCCCTGCGCATGGAGGTGGACCGGAGCCCAGGGCTGCCTATGAGCGACCTCAAAACGCATA ACGTCCACGTGGAGATTGAGCAGCGGTGGCATCAGGTGGAGACCACACCTCTCCGGGAAGAGAAGCAGGTGCCCATCGCCCCCGTCCACC TGTCTTCTGAAGATGGGGGTGACCGGCTCTCCACACACGAGCTGACCTCTCTGCTCGAGAAGGAGCTGGAGCAGAGCCAGAAGGAGGCCT CAGACCTTCTGGAGCAGAACCGGCTCCTGCAGGACCAGCTGAGGGTGGCCCTGGGCCGGGAGCAGAGCGCCCGTGAGGGCTACGTGCTGC AGGCCACGTGCGAGCGAGGGTTTGCAGCAATGGAAGAAACGCACCAGAAGAAGATTGAAGATCTCCAGAGGCAGCACCAGCGGGAGCTAG AGAAACTTCGAGAAGAGAAAGACCGCCTCCTAGCCGAGGAGACAGCGGCCACCATCTCAGCCATCGAAGCCATGAAGAACGCCCACCGGG AGGAAATGGAGCGGGAGCTGGAGAAGAGCCAGCGGTCCCAGATCAGCAGCGTCAACTCGGATGTTGAGGCCCTGCGGCGCCAGTACCTGG AGGAGCTGCAGTCGGTGCAGCGGGAACTGGAGGTCCTCTCGGAGCAGTACTCGCAGAAGTGCCTGGAGAATGCCCATCTGGCCCAGGCGC TGGAGGCCGAGCGGCAGGCCCTGCGGCAGTGCCAGCGTGAGAACCAGGAGCTCAATGCCCACAACCAGGAGCTGAACAACCGCCTGGCTG CAGAGATCACACGGTTGCGGACGCTGCTGACTGGGGACGGCGGTGGGGAGGCCACTGGGTCACCCCTTGCACAGGGCAAGGATGCCTATG AACTAGAGGTCTTATTGCGGGTAAAGGAATCGGAAATACAGTACCTGAAACAGGAGATTAGCTCCCTCAAGGATGAGCTGCAGACGGCAC TGCGGGACAAGAAGTACGCAAGTGACAAGTACAAAGACATCTACACAGAGCTCAGCATCGCGAAGGCTAAGGCTGACTGTGACATCAGCA GGTTGAAGGAGCAGCTCAAGGCTGCAACGGAAGCACTGGGGGAGAAGTCCCCTGACAGTGCCACGGTGTCCGGATATGATATAATGAAAT CTAAAAGCAACCCTGACTTCTTGAAGAAAGACAGATCCTGTGTCACCCGGCAACTCAGAAACATCAGGTCCAAGGATGCAATTCGAAGTC ACAGCGAATCAGCCTCACCTTCAGCCCTGTCCAGTAGCCCCAACAATCTGAGCCCAACAGGCTGGTCACAGCCGAAAACCCCCGTGCCAG CACAAAGAGAGCGGGCACCAGTATCTGGGACCCAGGAGAAAAACAAAATTAGGCCTCGTGGACAGAGAGATTCAAGCTATTATTGGGAAA TAGAAGCCAGTGAAGTGATGCTGTCCACTCGGATTGGGTCAGGCTCTTTTGGAACTGTTTATAAGGGTAAATGGCACGGAGATGTTGCAG TAAAGATCCTAAAGGTTGTCGACCCAACCCCAGAGCAATTCCAGGCCTTCAGGAATGAGGTGGCTGTTCTGCGCAAAACACGGCATGTGA ACATTCTGCTTTTCATGGGGTACATGACAAAGGACAACCTGGCAATTGTGACCCAGTGGTGCGAGGGCAGCAGCCTCTACAAACACCTGC ATGTCCAGGAGACCAAGTTTCAGATGTTCCAGCTAATTGACATTGCCCGGCAGACGGCTCAGGGAATGGACTATTTGCATGCAAAGAACA TCATCCATAGAGACATGAAATCCAACAATATATTTCTCCATGAAGGCTTAACAGTGAAAATTGGAGATTTTGGTTTGGCAACAGTAAAGT CACGCTGGAGTGGTTCTCAGCAGGTTGAACAACCTACTGGCTCTGTCCTCTGGATGGCCCCAGAGGTGATCCGAATGCAGGATAACAACC CATTCAGTTTCCAGTCGGATGTCTACTCCTATGGCATCGTATTGTATGAACTGATGACGGGGGAGCTTCCTTATTCTCACATCAACAACC GAGATCAGATCATCTTCATGGTGGGCCGAGGATATGCCTCCCCAGATCTTAGTAAGCTATATAAGAACTGCCCCAAAGCAATGAAGAGGC TGGTAGCTGACTGTGTGAAGAAAGTAAAGGAAGAGAGGCCTCTTTTTCCCCAGATCCTGTCTTCCATTGAGCTGCTCCAACACTCTCTAC CGAAGATCAACCGGAGCGCTTCCGAGCCATCCTTGCATCGGGCAGCCCACACTGAGGATATCAATGCTTGCACGCTGACCACGTCCCCGA GGCTGCCTGTCTTCTAGTTGACTTTGCACCTGTCTTCAGGCTGCCAGGGGAGGAGGAGAAGCCAGCAGGCACCACTTTTCTGCTCCCTTT CTCCAGAGGCAGAACACATGTTTTCAGAGAAGCTGCTGCTAAGGACCTTCTAGACTGCTCACAGGGCCTTAACTTCATGTTGCCTTCTTT >In-frame_ENST00000395811_ENST00000534997_TCGA-D9-A4Z6-06A_MPRIP_chr17_17083402_+_RAF1_chr3_12641914_length(amino acids)=1385AA_start in transcript=89_stop in transcript=4246 MSAAKENPCRKFQANIFNKSKCQNCFKPRESHLLNDEDLTQAKPIYGGWLLLAPDGTDFDNPVHRSRKWQRRFFILYEHGLLRYALDEMP TTLPQGTINMNQCTDVVDGEGRTGQKFSLCILTPEKEHFIRAETKEIVSGWLEMLMVYPRTNKQNQKKKRKVEPPTPQEPGPAKVAVTSS SSSSSSSSSIPSAEKVPTTKSTLWQEEMRTKDQPDGSSLSPAQSPSQSQPPAASSLREPGLESKEEESAMSSDRMDCGRKVRVESGYFSL EKTKQDLKAEEQQLPPPLSPPSPSTPNHRRSQVIEKFEALDIEKAEHMETNAVGPSPSSDTRQGRSEKRAFPRKRDFTNEAPPAPLPDAS ASPLSPHRRAKSLDRRSTEPSVTPDLLNFKKGWLTKQYEDGQWKKHWFVLADQSLRYYRDSVAEEAADLDGEIDLSACYDVTEYPVQRNY GFQIHTKEGEFTLSAMTSGIRRNWIQTIMKHVHPTTAPDVTSSLPEEKNKSSCSFETCPRPTEKQEAELGEPDPEQKRSRARERRREGRS KTFDWAEFRPIQQALAQERVGGVGPADTHEPLRPEAEPGELERERARRREERRKRFGMLDATDGPGTEDAALRMEVDRSPGLPMSDLKTH NVHVEIEQRWHQVETTPLREEKQVPIAPVHLSSEDGGDRLSTHELTSLLEKELEQSQKEASDLLEQNRLLQDQLRVALGREQSAREGYVL QATCERGFAAMEETHQKKIEDLQRQHQRELEKLREEKDRLLAEETAATISAIEAMKNAHREEMERELEKSQRSQISSVNSDVEALRRQYL EELQSVQRELEVLSEQYSQKCLENAHLAQALEAERQALRQCQRENQELNAHNQELNNRLAAEITRLRTLLTGDGGGEATGSPLAQGKDAY ELEVLLRVKESEIQYLKQEISSLKDELQTALRDKKYASDKYKDIYTELSIAKAKADCDISRLKEQLKAATEALGEKSPDSATVSGYDIMK SKSNPDFLKKDRSCVTRQLRNIRSKDAIRSHSESASPSALSSSPNNLSPTGWSQPKTPVPAQRERAPVSGTQEKNKIRPRGQRDSSYYWE IEASEVMLSTRIGSGSFGTVYKGKWHGDVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYMTKDNLAIVTQWCEGSSLYKHL HVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNN PFSFQSDVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCVKKVKEERPLFPQILSSIELLQHSL -------------------------------------------------------------- >In-frame_ENST00000395811_ENST00000542177_TCGA-D9-A4Z6-06A_MPRIP_chr17_17083402_+_RAF1_chr3_12641914_length(transcript)=4428nt_BP=3134nt GCGGCCGCGCTGAGCCCCTAGCCCGCCGGGAGCGCCAGGCCGGCCAGGCCTGCGCCGCCGCCGCCGCCGCCGTCGCCGCCGCGCCGACCA TGTCGGCAGCCAAGGAGAACCCGTGCAGGAAATTCCAGGCCAACATCTTCAACAAGAGCAAGTGTCAGAACTGCTTCAAGCCCCGCGAGT CGCATCTGCTCAACGACGAGGACCTGACGCAGGCAAAACCCATTTATGGCGGTTGGCTGCTCCTGGCTCCAGATGGGACCGACTTTGACA ACCCAGTGCACCGGTCTCGGAAATGGCAGCGACGGTTCTTCATCCTTTACGAGCACGGCCTCTTGCGCTACGCCCTGGATGAGATGCCCA CGACCCTTCCTCAGGGCACCATCAACATGAACCAGTGCACAGATGTGGTGGATGGGGAGGGCCGCACGGGCCAGAAGTTCTCCCTGTGTA TTCTGACGCCTGAGAAGGAGCATTTCATCCGGGCGGAGACCAAGGAGATCGTCAGTGGGTGGCTGGAGATGCTCATGGTCTATCCCCGGA CCAACAAGCAGAATCAGAAGAAGAAACGGAAAGTGGAGCCCCCCACACCACAGGAGCCTGGGCCTGCCAAGGTGGCTGTTACCAGCAGCA GCAGCAGCAGCAGCAGCAGCAGCAGCATCCCCAGTGCTGAGAAAGTCCCCACCACCAAGTCCACACTCTGGCAGGAAGAAATGAGGACCA AGGACCAGCCAGATGGCAGCAGCCTGAGTCCAGCTCAGAGTCCCAGCCAGAGCCAGCCTCCTGCTGCCAGCTCCCTGCGGGAACCTGGGC TAGAGAGCAAAGAAGAGGAGAGCGCCATGAGTAGCGACCGCATGGACTGTGGCCGCAAAGTCCGGGTGGAGAGCGGCTACTTCTCTCTGG AGAAGACCAAACAGGACTTGAAGGCTGAAGAACAGCAGCTGCCCCCGCCGCTCTCCCCTCCCAGCCCCAGCACCCCCAACCACAGGAGGT CCCAGGTGATTGAAAAGTTTGAGGCCTTGGACATTGAGAAGGCAGAGCACATGGAGACCAATGCAGTGGGGCCCTCACCATCCAGCGACA CACGCCAGGGCCGCAGCGAGAAGAGGGCGTTCCCTAGGAAGCGGGACTTCACCAATGAAGCCCCCCCAGCTCCTCTCCCAGACGCCTCGG CTTCCCCCCTGTCTCCACACCGAAGAGCCAAGTCACTGGACAGGAGGTCCACGGAGCCCTCCGTGACGCCCGACCTGCTGAATTTCAAGA AAGGCTGGCTGACTAAGCAGTATGAGGACGGCCAGTGGAAGAAACACTGGTTTGTCCTCGCCGATCAAAGCCTGAGATACTACAGGGATT CAGTGGCTGAGGAGGCAGCCGACTTGGATGGAGAAATTGACTTGTCCGCATGTTACGATGTCACAGAGTATCCAGTTCAGAGAAACTATG GCTTCCAGATACATACAAAGGAGGGCGAGTTTACCCTGTCGGCCATGACATCTGGGATTCGGCGGAACTGGATCCAGACCATCATGAAGC ACGTGCACCCGACCACTGCCCCGGATGTGACCAGCTCGTTGCCAGAGGAAAAAAACAAGAGCAGCTGCTCTTTTGAGACCTGCCCGAGGC CTACTGAGAAGCAAGAGGCAGAGCTGGGGGAGCCGGACCCTGAGCAGAAGAGGAGCCGCGCACGGGAGCGGAGGCGAGAGGGCCGCTCCA AGACCTTTGACTGGGCTGAGTTCCGTCCCATCCAGCAGGCCCTGGCTCAGGAGCGGGTGGGCGGCGTGGGGCCTGCTGACACCCACGAGC CCCTGCGCCCTGAGGCGGAGCCTGGGGAGCTGGAGCGGGAGCGTGCACGGAGGCGGGAGGAGCGCCGCAAGCGCTTCGGGATGCTCGACG CCACAGACGGGCCAGGCACTGAGGATGCAGCCCTGCGCATGGAGGTGGACCGGAGCCCAGGGCTGCCTATGAGCGACCTCAAAACGCATA ACGTCCACGTGGAGATTGAGCAGCGGTGGCATCAGGTGGAGACCACACCTCTCCGGGAAGAGAAGCAGGTGCCCATCGCCCCCGTCCACC TGTCTTCTGAAGATGGGGGTGACCGGCTCTCCACACACGAGCTGACCTCTCTGCTCGAGAAGGAGCTGGAGCAGAGCCAGAAGGAGGCCT CAGACCTTCTGGAGCAGAACCGGCTCCTGCAGGACCAGCTGAGGGTGGCCCTGGGCCGGGAGCAGAGCGCCCGTGAGGGCTACGTGCTGC AGGCCACGTGCGAGCGAGGGTTTGCAGCAATGGAAGAAACGCACCAGAAGAAGATTGAAGATCTCCAGAGGCAGCACCAGCGGGAGCTAG AGAAACTTCGAGAAGAGAAAGACCGCCTCCTAGCCGAGGAGACAGCGGCCACCATCTCAGCCATCGAAGCCATGAAGAACGCCCACCGGG AGGAAATGGAGCGGGAGCTGGAGAAGAGCCAGCGGTCCCAGATCAGCAGCGTCAACTCGGATGTTGAGGCCCTGCGGCGCCAGTACCTGG AGGAGCTGCAGTCGGTGCAGCGGGAACTGGAGGTCCTCTCGGAGCAGTACTCGCAGAAGTGCCTGGAGAATGCCCATCTGGCCCAGGCGC TGGAGGCCGAGCGGCAGGCCCTGCGGCAGTGCCAGCGTGAGAACCAGGAGCTCAATGCCCACAACCAGGAGCTGAACAACCGCCTGGCTG CAGAGATCACACGGTTGCGGACGCTGCTGACTGGGGACGGCGGTGGGGAGGCCACTGGGTCACCCCTTGCACAGGGCAAGGATGCCTATG AACTAGAGGTCTTATTGCGGGTAAAGGAATCGGAAATACAGTACCTGAAACAGGAGATTAGCTCCCTCAAGGATGAGCTGCAGACGGCAC TGCGGGACAAGAAGTACGCAAGTGACAAGTACAAAGACATCTACACAGAGCTCAGCATCGCGAAGGCTAAGGCTGACTGTGACATCAGCA GGTTGAAGGAGCAGCTCAAGGCTGCAACGGAAGCACTGGGGGAGAAGTCCCCTGACAGTGCCACGGTGTCCGGATATGATATAATGAAAT CTAAAAGCAACCCTGACTTCTTGAAGAAAGACAGATCCTGTGTCACCCGGCAACTCAGAAACATCAGGTCCAAGGATGCAATTCGAAGTC ACAGCGAATCAGCCTCACCTTCAGCCCTGTCCAGTAGCCCCAACAATCTGAGCCCAACAGGCTGGTCACAGCCGAAAACCCCCGTGCCAG CACAAAGAGAGCGGGCACCAGTATCTGGGACCCAGGAGAAAAACAAAATTAGGCCTCGTGGACAGAGAGATTCAAGCTATTATTGGGAAA TAGAAGCCAGTGAAGTGATGCTGTCCACTCGGATTGGGTCAGGCTCTTTTGGAACTGTTTATAAGGGTAAATGGCACGGAGATGTTGCAG TAAAGATCCTAAAGGTTGTCGACCCAACCCCAGAGCAATTCCAGGCCTTCAGGAATGAGGTGGCTGTTCTGCGCAAAACACGGCATGTGA ACATTCTGCTTTTCATGGGGTACATGACAAAGGACAACCTGGCAATTGTGACCCAGTGGTGCGAGGGCAGCAGCCTCTACAAACACCTGC ATGTCCAGGAGACCAAGTTTCAGATGTTCCAGCTAATTGACATTGCCCGGCAGACGGCTCAGGGAATGGACTATTTGCATGCAAAGAACA TCATCCATAGAGACATGAAATCCAACAATATATTTCTCCATGAAGGCTTAACAGTGAAAATTGGAGATTTTGGTTTGGCAACAGTAAAGT CACGCTGGAGTGGTTCTCAGCAGGTTGAACAACCTACTGGCTCTGTCCTCTGGATGGCCCCAGAGGTGATCCGAATGCAGGATAACAACC CATTCAGTTTCCAGTCGGATGTCTACTCCTATGGCATCGTATTGTATGAACTGATGACGGGGGAGCTTCCTTATTCTCACATCAACAACC GAGATCAGATCATCTTCATGGTGGGCCGAGGATATGCCTCCCCAGATCTTAGTAAGCTATATAAGAACTGCCCCAAAGCAATGAAGAGGC TGGTAGCTGACTGTGTGAAGAAAGTAAAGGAAGAGAGGCCTCTTTTTCCCCAGATCCTGTCTTCCATTGAGCTGCTCCAACACTCTCTAC CGAAGATCAACCGGAGCGCTTCCGAGCCATCCTTGCATCGGGCAGCCCACACTGAGGATATCAATGCTTGCACGCTGACCACGTCCCCGA GGCTGCCTGTCTTCTAGTTGACTTTGCACCTGTCTTCAGGCTGCCAGGGGAGGAGGAGAAGCCAGCAGGCACCACTTTTCTGCTCCCTTT CTCCAGAGGCAGAACACATGTTTTCAGAGAAGCTGCTGCTAAGGACCTTCTAGACTGCTCACAGGGCCTTAACTTCATGTTGCCTTCTTT >In-frame_ENST00000395811_ENST00000542177_TCGA-D9-A4Z6-06A_MPRIP_chr17_17083402_+_RAF1_chr3_12641914_length(amino acids)=1385AA_start in transcript=89_stop in transcript=4246 MSAAKENPCRKFQANIFNKSKCQNCFKPRESHLLNDEDLTQAKPIYGGWLLLAPDGTDFDNPVHRSRKWQRRFFILYEHGLLRYALDEMP TTLPQGTINMNQCTDVVDGEGRTGQKFSLCILTPEKEHFIRAETKEIVSGWLEMLMVYPRTNKQNQKKKRKVEPPTPQEPGPAKVAVTSS SSSSSSSSSIPSAEKVPTTKSTLWQEEMRTKDQPDGSSLSPAQSPSQSQPPAASSLREPGLESKEEESAMSSDRMDCGRKVRVESGYFSL EKTKQDLKAEEQQLPPPLSPPSPSTPNHRRSQVIEKFEALDIEKAEHMETNAVGPSPSSDTRQGRSEKRAFPRKRDFTNEAPPAPLPDAS ASPLSPHRRAKSLDRRSTEPSVTPDLLNFKKGWLTKQYEDGQWKKHWFVLADQSLRYYRDSVAEEAADLDGEIDLSACYDVTEYPVQRNY GFQIHTKEGEFTLSAMTSGIRRNWIQTIMKHVHPTTAPDVTSSLPEEKNKSSCSFETCPRPTEKQEAELGEPDPEQKRSRARERRREGRS KTFDWAEFRPIQQALAQERVGGVGPADTHEPLRPEAEPGELERERARRREERRKRFGMLDATDGPGTEDAALRMEVDRSPGLPMSDLKTH NVHVEIEQRWHQVETTPLREEKQVPIAPVHLSSEDGGDRLSTHELTSLLEKELEQSQKEASDLLEQNRLLQDQLRVALGREQSAREGYVL QATCERGFAAMEETHQKKIEDLQRQHQRELEKLREEKDRLLAEETAATISAIEAMKNAHREEMERELEKSQRSQISSVNSDVEALRRQYL EELQSVQRELEVLSEQYSQKCLENAHLAQALEAERQALRQCQRENQELNAHNQELNNRLAAEITRLRTLLTGDGGGEATGSPLAQGKDAY ELEVLLRVKESEIQYLKQEISSLKDELQTALRDKKYASDKYKDIYTELSIAKAKADCDISRLKEQLKAATEALGEKSPDSATVSGYDIMK SKSNPDFLKKDRSCVTRQLRNIRSKDAIRSHSESASPSALSSSPNNLSPTGWSQPKTPVPAQRERAPVSGTQEKNKIRPRGQRDSSYYWE IEASEVMLSTRIGSGSFGTVYKGKWHGDVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYMTKDNLAIVTQWCEGSSLYKHL HVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNN PFSFQSDVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCVKKVKEERPLFPQILSSIELLQHSL -------------------------------------------------------------- >In-frame_ENST00000444976_ENST00000251849_TCGA-D9-A4Z6-06A_MPRIP_chr17_17083402_+_RAF1_chr3_12641914_length(transcript)=5037nt_BP=3011nt CTGAGCCCCTAGCCCGCCGGGAGCGCCAGGCCGGCCAGGCCTGCGCCGCCGCCGCCGCCGCCGTCGCCGCCGCGCCGACCATGTCGGCAG CCAAGGAGAACCCGTGCAGGAAATTCCAGGCCAACATCTTCAACAAGAGCAAGTGTCAGAACTGCTTCAAGCCCCGCGAGTCGCATCTGC TCAACGACGAGGACCTGACGCAGGCAAAACCCATTTATGGCGGTTGGCTGCTCCTGGCTCCAGATGGGACCGACTTTGACAACCCAGTGC ACCGGTCTCGGAAATGGCAGCGACGGTTCTTCATCCTTTACGAGCACGGCCTCTTGCGCTACGCCCTGGATGAGATGCCCACGACCCTTC CTCAGGGCACCATCAACATGAACCAGTGCACAGATGTGGTGGATGGGGAGGGCCGCACGGGCCAGAAGTTCTCCCTGTGTATTCTGACGC CTGAGAAGGAGCATTTCATCCGGGCGGAGACCAAGGAGATCGTCAGTGGGTGGCTGGAGATGCTCATGGTCTATCCCCGGACCAACAAGC AGAATCAGAAGAAGAAACGGAAAGTGGAGCCCCCCACACCACAGGAGCCTGGGCCTGCCAAGGTGGCTGTTACCAGCAGCAGCAGCAGCA GCAGCAGCAGCAGCAGCATCCCCAGTGCTGAGAAAGTCCCCACCACCAAGTCCACACTCTGGCAGGAAGAAATGAGGACCAAGGACCAGC CAGATGGCAGCAGCCTGAGTCCAGCTCAGAGTCCCAGCCAGAGCCAGCCTCCTGCTGCCAGCTCCCTGCGGGAACCTGGGCTAGAGAGCA AAGAAGAGGAGAGCGCCATGAGTAGCGACCGCATGGACTGTGGCCGCAAAGTCCGGGTGGAGAGCGGCTACTTCTCTCTGGAGAAGACCA AACAGGACTTGAAGGCTGAAGAACAGCAGCTGCCCCCGCCGCTCTCCCCTCCCAGCCCCAGCACCCCCAACCACAGGAGGTCCCAGGTGA TTGAAAAGTTTGAGGCCTTGGACATTGAGAAGGCAGAGCACATGGAGACCAATGCAGTGGGGCCCTCACCATCCAGCGACACACGCCAGG GCCGCAGCGAGAAGAGGGCGTTCCCTAGGAAGCGGCCCGACCTGCTGAATTTCAAGAAAGGCTGGCTGACTAAGCAGTATGAGGACGGCC AGTGGAAGAAACACTGGTTTGTCCTCGCCGATCAAAGCCTGAGATACTACAGGGATTCAGTGGCTGAGGAGGCAGCCGACTTGGATGGAG AAATTGACTTGTCCGCATGTTACGATGTCACAGAGTATCCAGTTCAGAGAAACTATGGCTTCCAGATACATACAAAGGAGGGCGAGTTTA CCCTGTCGGCCATGACATCTGGGATTCGGCGGAACTGGATCCAGACCATCATGAAGCACGTGCACCCGACCACTGCCCCGGATGTGACCA GCTCGTTGCCAGAGGAAAAAAACAAGAGCAGCTGCTCTTTTGAGACCTGCCCGAGGCCTACTGAGAAGCAAGAGGCAGAGCTGGGGGAGC CGGACCCTGAGCAGAAGAGGAGCCGCGCACGGGAGCGGAGGCGAGAGGGCCGCTCCAAGACCTTTGACTGGGCTGAGTTCCGTCCCATCC AGCAGGCCCTGGCTCAGGAGCGGGTGGGCGGCGTGGGGCCTGCTGACACCCACGAGCCCCTGCGCCCTGAGGCGGAGCCTGGGGAGCTGG AGCGGGAGCGTGCACGGAGGCGGGAGGAGCGCCGCAAGCGCTTCGGGATGCTCGACGCCACAGACGGGCCAGGCACTGAGGATGCAGCCC TGCGCATGGAGGTGGACCGGAGCCCAGGGCTGCCTATGAGCGACCTCAAAACGCATAACGTCCACGTGGAGATTGAGCAGCGGTGGCATC AGGTGGAGACCACACCTCTCCGGGAAGAGAAGCAGGTGCCCATCGCCCCCGTCCACCTGTCTTCTGAAGATGGGGGTGACCGGCTCTCCA CACACGAGCTGACCTCTCTGCTCGAGAAGGAGCTGGAGCAGAGCCAGAAGGAGGCCTCAGACCTTCTGGAGCAGAACCGGCTCCTGCAGG ACCAGCTGAGGGTGGCCCTGGGCCGGGAGCAGAGCGCCCGTGAGGGCTACGTGCTGCAGGCCACGTGCGAGCGAGGGTTTGCAGCAATGG AAGAAACGCACCAGAAGAAGATTGAAGATCTCCAGAGGCAGCACCAGCGGGAGCTAGAGAAACTTCGAGAAGAGAAAGACCGCCTCCTAG CCGAGGAGACAGCGGCCACCATCTCAGCCATCGAAGCCATGAAGAACGCCCACCGGGAGGAAATGGAGCGGGAGCTGGAGAAGAGCCAGC GGTCCCAGATCAGCAGCGTCAACTCGGATGTTGAGGCCCTGCGGCGCCAGTACCTGGAGGAGCTGCAGTCGGTGCAGCGGGAACTGGAGG TCCTCTCGGAGCAGTACTCGCAGAAGTGCCTGGAGAATGCCCATCTGGCCCAGGCGCTGGAGGCCGAGCGGCAGGCCCTGCGGCAGTGCC AGCGTGAGAACCAGGAGCTCAATGCCCACAACCAGGAGCTGAACAACCGCCTGGCTGCAGAGATCACACGGTTGCGGACGCTGCTGACTG GGGACGGCGGTGGGGAGGCCACTGGGTCACCCCTTGCACAGGGCAAGGATGCCTATGAACTAGAGGTCTTATTGCGGGTAAAGGAATCGG AAATACAGTACCTGAAACAGGAGATTAGCTCCCTCAAGGATGAGCTGCAGACGGCACTGCGGGACAAGAAGTACGCAAGTGACAAGTACA AAGACATCTACACAGAGCTCAGCATCGCGAAGGCTAAGGCTGACTGTGACATCAGCAGGTTGAAGGAGCAGCTCAAGGCTGCAACGGAAG CACTGGGGGAGAAGTCCCCTGACAGTGCCACGGTGTCCGGATATGATATAATGAAATCTAAAAGCAACCCTGACTTCTTGAAGAAAGACA GATCCTGTGTCACCCGGCAACTCAGAAACATCAGGTCCAAGGATGCAATTCGAAGTCACAGCGAATCAGCCTCACCTTCAGCCCTGTCCA GTAGCCCCAACAATCTGAGCCCAACAGGCTGGTCACAGCCGAAAACCCCCGTGCCAGCACAAAGAGAGCGGGCACCAGTATCTGGGACCC AGGAGAAAAACAAAATTAGGCCTCGTGGACAGAGAGATTCAAGCTATTATTGGGAAATAGAAGCCAGTGAAGTGATGCTGTCCACTCGGA TTGGGTCAGGCTCTTTTGGAACTGTTTATAAGGGTAAATGGCACGGAGATGTTGCAGTAAAGATCCTAAAGGTTGTCGACCCAACCCCAG AGCAATTCCAGGCCTTCAGGAATGAGGTGGCTGTTCTGCGCAAAACACGGCATGTGAACATTCTGCTTTTCATGGGGTACATGACAAAGG ACAACCTGGCAATTGTGACCCAGTGGTGCGAGGGCAGCAGCCTCTACAAACACCTGCATGTCCAGGAGACCAAGTTTCAGATGTTCCAGC TAATTGACATTGCCCGGCAGACGGCTCAGGGAATGGACTATTTGCATGCAAAGAACATCATCCATAGAGACATGAAATCCAACAATATAT TTCTCCATGAAGGCTTAACAGTGAAAATTGGAGATTTTGGTTTGGCAACAGTAAAGTCACGCTGGAGTGGTTCTCAGCAGGTTGAACAAC CTACTGGCTCTGTCCTCTGGATGGCCCCAGAGGTGATCCGAATGCAGGATAACAACCCATTCAGTTTCCAGTCGGATGTCTACTCCTATG GCATCGTATTGTATGAACTGATGACGGGGGAGCTTCCTTATTCTCACATCAACAACCGAGATCAGATCATCTTCATGGTGGGCCGAGGAT ATGCCTCCCCAGATCTTAGTAAGCTATATAAGAACTGCCCCAAAGCAATGAAGAGGCTGGTAGCTGACTGTGTGAAGAAAGTAAAGGAAG AGAGGCCTCTTTTTCCCCAGATCCTGTCTTCCATTGAGCTGCTCCAACACTCTCTACCGAAGATCAACCGGAGCGCTTCCGAGCCATCCT TGCATCGGGCAGCCCACACTGAGGATATCAATGCTTGCACGCTGACCACGTCCCCGAGGCTGCCTGTCTTCTAGTTGACTTTGCACCTGT CTTCAGGCTGCCAGGGGAGGAGGAGAAGCCAGCAGGCACCACTTTTCTGCTCCCTTTCTCCAGAGGCAGAACACATGTTTTCAGAGAAGC TGCTGCTAAGGACCTTCTAGACTGCTCACAGGGCCTTAACTTCATGTTGCCTTCTTTTCTATCCCTTTGGGCCCTGGGAGAAGGAAGCCA TTTGCAGTGCTGGTGTGTCCTGCTCCCTCCCCACATTCCCCATGCTCAAGGCCCAGCCTTCTGTAGATGCGCAAGTGGATGTTGATGGTA GTACAAAAAGCAGGGGCCCAGCCCCAGCTGTTGGCTACATGAGTATTTAGAGGAAGTAAGGTAGCAGGCAGTCCAGCCCTGATGTGGAGA CACATGGGATTTTGGAAATCAGCTTCTGGAGGAATGCATGTCACAGGCGGGACTTTCTTCAGAGAGTGGTGCAGCGCCAGACATTTTGCA CATAAGGCACCAAACAGCCCAGGACTGCCGAGACTCTGGCCGCCCGAAGGAGCCTGCTTTGGTACTATGGAACTTTTCTTAGGGGACACG TCCTCCTTTCACAGCTTCTAAGGTGTCCAGTGCATTGGGATGGTTTTCCAGGCAAGGCACTCGGCCAATCCGCATCTCAGCCCTCTCAGG GAGCAGTCTTCCATCATGCTGAATTTTGTCTTCCAGGAGCTGCCCCTATGGGGCGGGGCCGCAGGGCCAGCCTTGTTTCTCTAACAAACA AACAAACAAACAGCCTTGTTTCTCTAGTCACATCATGTGTATACAAGGAAGCCAGGAATACAGGTTTTCTTGATGATTTGGGTTTTAATT >In-frame_ENST00000444976_ENST00000251849_TCGA-D9-A4Z6-06A_MPRIP_chr17_17083402_+_RAF1_chr3_12641914_length(amino acids)=1347AA_start in transcript=80_stop in transcript=4123 MSAAKENPCRKFQANIFNKSKCQNCFKPRESHLLNDEDLTQAKPIYGGWLLLAPDGTDFDNPVHRSRKWQRRFFILYEHGLLRYALDEMP TTLPQGTINMNQCTDVVDGEGRTGQKFSLCILTPEKEHFIRAETKEIVSGWLEMLMVYPRTNKQNQKKKRKVEPPTPQEPGPAKVAVTSS SSSSSSSSSIPSAEKVPTTKSTLWQEEMRTKDQPDGSSLSPAQSPSQSQPPAASSLREPGLESKEEESAMSSDRMDCGRKVRVESGYFSL EKTKQDLKAEEQQLPPPLSPPSPSTPNHRRSQVIEKFEALDIEKAEHMETNAVGPSPSSDTRQGRSEKRAFPRKRPDLLNFKKGWLTKQY EDGQWKKHWFVLADQSLRYYRDSVAEEAADLDGEIDLSACYDVTEYPVQRNYGFQIHTKEGEFTLSAMTSGIRRNWIQTIMKHVHPTTAP DVTSSLPEEKNKSSCSFETCPRPTEKQEAELGEPDPEQKRSRARERRREGRSKTFDWAEFRPIQQALAQERVGGVGPADTHEPLRPEAEP GELERERARRREERRKRFGMLDATDGPGTEDAALRMEVDRSPGLPMSDLKTHNVHVEIEQRWHQVETTPLREEKQVPIAPVHLSSEDGGD RLSTHELTSLLEKELEQSQKEASDLLEQNRLLQDQLRVALGREQSAREGYVLQATCERGFAAMEETHQKKIEDLQRQHQRELEKLREEKD RLLAEETAATISAIEAMKNAHREEMERELEKSQRSQISSVNSDVEALRRQYLEELQSVQRELEVLSEQYSQKCLENAHLAQALEAERQAL RQCQRENQELNAHNQELNNRLAAEITRLRTLLTGDGGGEATGSPLAQGKDAYELEVLLRVKESEIQYLKQEISSLKDELQTALRDKKYAS DKYKDIYTELSIAKAKADCDISRLKEQLKAATEALGEKSPDSATVSGYDIMKSKSNPDFLKKDRSCVTRQLRNIRSKDAIRSHSESASPS ALSSSPNNLSPTGWSQPKTPVPAQRERAPVSGTQEKNKIRPRGQRDSSYYWEIEASEVMLSTRIGSGSFGTVYKGKWHGDVAVKILKVVD PTPEQFQAFRNEVAVLRKTRHVNILLFMGYMTKDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKS NNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSDVYSYGIVLYELMTGELPYSHINNRDQIIFMV -------------------------------------------------------------- >In-frame_ENST00000444976_ENST00000442415_TCGA-D9-A4Z6-06A_MPRIP_chr17_17083402_+_RAF1_chr3_12641914_length(transcript)=4840nt_BP=3011nt CTGAGCCCCTAGCCCGCCGGGAGCGCCAGGCCGGCCAGGCCTGCGCCGCCGCCGCCGCCGCCGTCGCCGCCGCGCCGACCATGTCGGCAG CCAAGGAGAACCCGTGCAGGAAATTCCAGGCCAACATCTTCAACAAGAGCAAGTGTCAGAACTGCTTCAAGCCCCGCGAGTCGCATCTGC TCAACGACGAGGACCTGACGCAGGCAAAACCCATTTATGGCGGTTGGCTGCTCCTGGCTCCAGATGGGACCGACTTTGACAACCCAGTGC ACCGGTCTCGGAAATGGCAGCGACGGTTCTTCATCCTTTACGAGCACGGCCTCTTGCGCTACGCCCTGGATGAGATGCCCACGACCCTTC CTCAGGGCACCATCAACATGAACCAGTGCACAGATGTGGTGGATGGGGAGGGCCGCACGGGCCAGAAGTTCTCCCTGTGTATTCTGACGC CTGAGAAGGAGCATTTCATCCGGGCGGAGACCAAGGAGATCGTCAGTGGGTGGCTGGAGATGCTCATGGTCTATCCCCGGACCAACAAGC AGAATCAGAAGAAGAAACGGAAAGTGGAGCCCCCCACACCACAGGAGCCTGGGCCTGCCAAGGTGGCTGTTACCAGCAGCAGCAGCAGCA GCAGCAGCAGCAGCAGCATCCCCAGTGCTGAGAAAGTCCCCACCACCAAGTCCACACTCTGGCAGGAAGAAATGAGGACCAAGGACCAGC CAGATGGCAGCAGCCTGAGTCCAGCTCAGAGTCCCAGCCAGAGCCAGCCTCCTGCTGCCAGCTCCCTGCGGGAACCTGGGCTAGAGAGCA AAGAAGAGGAGAGCGCCATGAGTAGCGACCGCATGGACTGTGGCCGCAAAGTCCGGGTGGAGAGCGGCTACTTCTCTCTGGAGAAGACCA AACAGGACTTGAAGGCTGAAGAACAGCAGCTGCCCCCGCCGCTCTCCCCTCCCAGCCCCAGCACCCCCAACCACAGGAGGTCCCAGGTGA TTGAAAAGTTTGAGGCCTTGGACATTGAGAAGGCAGAGCACATGGAGACCAATGCAGTGGGGCCCTCACCATCCAGCGACACACGCCAGG GCCGCAGCGAGAAGAGGGCGTTCCCTAGGAAGCGGCCCGACCTGCTGAATTTCAAGAAAGGCTGGCTGACTAAGCAGTATGAGGACGGCC AGTGGAAGAAACACTGGTTTGTCCTCGCCGATCAAAGCCTGAGATACTACAGGGATTCAGTGGCTGAGGAGGCAGCCGACTTGGATGGAG AAATTGACTTGTCCGCATGTTACGATGTCACAGAGTATCCAGTTCAGAGAAACTATGGCTTCCAGATACATACAAAGGAGGGCGAGTTTA CCCTGTCGGCCATGACATCTGGGATTCGGCGGAACTGGATCCAGACCATCATGAAGCACGTGCACCCGACCACTGCCCCGGATGTGACCA GCTCGTTGCCAGAGGAAAAAAACAAGAGCAGCTGCTCTTTTGAGACCTGCCCGAGGCCTACTGAGAAGCAAGAGGCAGAGCTGGGGGAGC CGGACCCTGAGCAGAAGAGGAGCCGCGCACGGGAGCGGAGGCGAGAGGGCCGCTCCAAGACCTTTGACTGGGCTGAGTTCCGTCCCATCC AGCAGGCCCTGGCTCAGGAGCGGGTGGGCGGCGTGGGGCCTGCTGACACCCACGAGCCCCTGCGCCCTGAGGCGGAGCCTGGGGAGCTGG AGCGGGAGCGTGCACGGAGGCGGGAGGAGCGCCGCAAGCGCTTCGGGATGCTCGACGCCACAGACGGGCCAGGCACTGAGGATGCAGCCC TGCGCATGGAGGTGGACCGGAGCCCAGGGCTGCCTATGAGCGACCTCAAAACGCATAACGTCCACGTGGAGATTGAGCAGCGGTGGCATC AGGTGGAGACCACACCTCTCCGGGAAGAGAAGCAGGTGCCCATCGCCCCCGTCCACCTGTCTTCTGAAGATGGGGGTGACCGGCTCTCCA CACACGAGCTGACCTCTCTGCTCGAGAAGGAGCTGGAGCAGAGCCAGAAGGAGGCCTCAGACCTTCTGGAGCAGAACCGGCTCCTGCAGG ACCAGCTGAGGGTGGCCCTGGGCCGGGAGCAGAGCGCCCGTGAGGGCTACGTGCTGCAGGCCACGTGCGAGCGAGGGTTTGCAGCAATGG AAGAAACGCACCAGAAGAAGATTGAAGATCTCCAGAGGCAGCACCAGCGGGAGCTAGAGAAACTTCGAGAAGAGAAAGACCGCCTCCTAG CCGAGGAGACAGCGGCCACCATCTCAGCCATCGAAGCCATGAAGAACGCCCACCGGGAGGAAATGGAGCGGGAGCTGGAGAAGAGCCAGC GGTCCCAGATCAGCAGCGTCAACTCGGATGTTGAGGCCCTGCGGCGCCAGTACCTGGAGGAGCTGCAGTCGGTGCAGCGGGAACTGGAGG TCCTCTCGGAGCAGTACTCGCAGAAGTGCCTGGAGAATGCCCATCTGGCCCAGGCGCTGGAGGCCGAGCGGCAGGCCCTGCGGCAGTGCC AGCGTGAGAACCAGGAGCTCAATGCCCACAACCAGGAGCTGAACAACCGCCTGGCTGCAGAGATCACACGGTTGCGGACGCTGCTGACTG GGGACGGCGGTGGGGAGGCCACTGGGTCACCCCTTGCACAGGGCAAGGATGCCTATGAACTAGAGGTCTTATTGCGGGTAAAGGAATCGG AAATACAGTACCTGAAACAGGAGATTAGCTCCCTCAAGGATGAGCTGCAGACGGCACTGCGGGACAAGAAGTACGCAAGTGACAAGTACA AAGACATCTACACAGAGCTCAGCATCGCGAAGGCTAAGGCTGACTGTGACATCAGCAGGTTGAAGGAGCAGCTCAAGGCTGCAACGGAAG CACTGGGGGAGAAGTCCCCTGACAGTGCCACGGTGTCCGGATATGATATAATGAAATCTAAAAGCAACCCTGACTTCTTGAAGAAAGACA GATCCTGTGTCACCCGGCAACTCAGAAACATCAGGTCCAAGGATGCAATTCGAAGTCACAGCGAATCAGCCTCACCTTCAGCCCTGTCCA GTAGCCCCAACAATCTGAGCCCAACAGGCTGGTCACAGCCGAAAACCCCCGTGCCAGCACAAAGAGAGCGGGCACCAGTATCTGGGACCC AGGAGAAAAACAAAATTAGGCCTCGTGGACAGAGAGATTCAAGCTATTATTGGGAAATAGAAGCCAGTGAAGTGATGCTGTCCACTCGGA TTGGGTCAGGCTCTTTTGGAACTGTTTATAAGGGTAAATGGCACGGAGATGTTGCAGTAAAGATCCTAAAGGTTGTCGACCCAACCCCAG AGCAATTCCAGGCCTTCAGGAATGAGGTGGCTGTTCTGCGCAAAACACGGCATGTGAACATTCTGCTTTTCATGGGGTACATGACAAAGG ACAACCTGGCAATTGTGACCCAGTGGTGCGAGGGCAGCAGCCTCTACAAACACCTGCATGTCCAGGAGACCAAGTTTCAGATGTTCCAGC TAATTGACATTGCCCGGCAGACGGCTCAGGGAATGGACTATTTGCATGCAAAGAACATCATCCATAGAGACATGAAATCCAACAATATAT TTCTCCATGAAGGCTTAACAGTGAAAATTGGAGATTTTGGTTTGGCAACAGTAAAGTCACGCTGGAGTGGTTCTCAGCAGGTTGAACAAC CTACTGGCTCTGTCCTCTGGATGGCCCCAGAGGTGATCCGAATGCAGGATAACAACCCATTCAGTTTCCAGTCGGATGTCTACTCCTATG GCATCGTATTGTATGAACTGATGACGGGGGAGCTTCCTTATTCTCACATCAACAACCGAGATCAGATCATCTTCATGGTGGGCCGAGGAT ATGCCTCCCCAGATCTTAGTAAGCTATATAAGAACTGCCCCAAAGCAATGAAGAGGCTGGTAGCTGACTGTGTGAAGAAAGTAAAGGAAG AGAGGCCTCTTTTTCCCCAGATCCTGTCTTCCATTGAGCTGCTCCAACACTCTCTACCGAAGATCAACCGGAGCGCTTCCGAGCCATCCT TGCATCGGGCAGCCCACACTGAGGATATCAATGCTTGCACGCTGACCACGTCCCCGAGGCTGCCTGTCTTCTAGTTGACTTTGCACCTGT CTTCAGGCTGCCAGGGGAGGAGGAGAAGCCAGCAGGCACCACTTTTCTGCTCCCTTTCTCCAGAGGCAGAACACATGTTTTCAGAGAAGC TGCTGCTAAGGACCTTCTAGACTGCTCACAGGGCCTTAACTTCATGTTGCCTTCTTTTCTATCCCTTTGGGCCCTGGGAGAAGGAAGCCA TTTGCAGTGCTGGTGTGTCCTGCTCCCTCCCCACATTCCCCATGCTCAAGGCCCAGCCTTCTGTAGATGCGCAAGTGGATGTTGATGGTA GTACAAAAAGCAGGGGCCCAGCCCCAGCTGTTGGCTACATGAGTATTTAGAGGAAGTAAGGTAGCAGGCAGTCCAGCCCTGATGTGGAGA CACATGGGATTTTGGAAATCAGCTTCTGGAGGAATGCATGTCACAGGCGGGACTTTCTTCAGAGAGTGGTGCAGCGCCAGACATTTTGCA CATAAGGCACCAAACAGCCCAGGACTGCCGAGACTCTGGCCGCCCGAAGGAGCCTGCTTTGGTACTATGGAACTTTTCTTAGGGGACACG TCCTCCTTTCACAGCTTCTAAGGTGTCCAGTGCATTGGGATGGTTTTCCAGGCAAGGCACTCGGCCAATCCGCATCTCAGCCCTCTCAGG >In-frame_ENST00000444976_ENST00000442415_TCGA-D9-A4Z6-06A_MPRIP_chr17_17083402_+_RAF1_chr3_12641914_length(amino acids)=1347AA_start in transcript=80_stop in transcript=4123 MSAAKENPCRKFQANIFNKSKCQNCFKPRESHLLNDEDLTQAKPIYGGWLLLAPDGTDFDNPVHRSRKWQRRFFILYEHGLLRYALDEMP TTLPQGTINMNQCTDVVDGEGRTGQKFSLCILTPEKEHFIRAETKEIVSGWLEMLMVYPRTNKQNQKKKRKVEPPTPQEPGPAKVAVTSS SSSSSSSSSIPSAEKVPTTKSTLWQEEMRTKDQPDGSSLSPAQSPSQSQPPAASSLREPGLESKEEESAMSSDRMDCGRKVRVESGYFSL EKTKQDLKAEEQQLPPPLSPPSPSTPNHRRSQVIEKFEALDIEKAEHMETNAVGPSPSSDTRQGRSEKRAFPRKRPDLLNFKKGWLTKQY EDGQWKKHWFVLADQSLRYYRDSVAEEAADLDGEIDLSACYDVTEYPVQRNYGFQIHTKEGEFTLSAMTSGIRRNWIQTIMKHVHPTTAP DVTSSLPEEKNKSSCSFETCPRPTEKQEAELGEPDPEQKRSRARERRREGRSKTFDWAEFRPIQQALAQERVGGVGPADTHEPLRPEAEP GELERERARRREERRKRFGMLDATDGPGTEDAALRMEVDRSPGLPMSDLKTHNVHVEIEQRWHQVETTPLREEKQVPIAPVHLSSEDGGD RLSTHELTSLLEKELEQSQKEASDLLEQNRLLQDQLRVALGREQSAREGYVLQATCERGFAAMEETHQKKIEDLQRQHQRELEKLREEKD RLLAEETAATISAIEAMKNAHREEMERELEKSQRSQISSVNSDVEALRRQYLEELQSVQRELEVLSEQYSQKCLENAHLAQALEAERQAL RQCQRENQELNAHNQELNNRLAAEITRLRTLLTGDGGGEATGSPLAQGKDAYELEVLLRVKESEIQYLKQEISSLKDELQTALRDKKYAS DKYKDIYTELSIAKAKADCDISRLKEQLKAATEALGEKSPDSATVSGYDIMKSKSNPDFLKKDRSCVTRQLRNIRSKDAIRSHSESASPS ALSSSPNNLSPTGWSQPKTPVPAQRERAPVSGTQEKNKIRPRGQRDSSYYWEIEASEVMLSTRIGSGSFGTVYKGKWHGDVAVKILKVVD PTPEQFQAFRNEVAVLRKTRHVNILLFMGYMTKDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKS NNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSDVYSYGIVLYELMTGELPYSHINNRDQIIFMV -------------------------------------------------------------- >In-frame_ENST00000444976_ENST00000534997_TCGA-D9-A4Z6-06A_MPRIP_chr17_17083402_+_RAF1_chr3_12641914_length(transcript)=4371nt_BP=3011nt CTGAGCCCCTAGCCCGCCGGGAGCGCCAGGCCGGCCAGGCCTGCGCCGCCGCCGCCGCCGCCGTCGCCGCCGCGCCGACCATGTCGGCAG CCAAGGAGAACCCGTGCAGGAAATTCCAGGCCAACATCTTCAACAAGAGCAAGTGTCAGAACTGCTTCAAGCCCCGCGAGTCGCATCTGC TCAACGACGAGGACCTGACGCAGGCAAAACCCATTTATGGCGGTTGGCTGCTCCTGGCTCCAGATGGGACCGACTTTGACAACCCAGTGC ACCGGTCTCGGAAATGGCAGCGACGGTTCTTCATCCTTTACGAGCACGGCCTCTTGCGCTACGCCCTGGATGAGATGCCCACGACCCTTC CTCAGGGCACCATCAACATGAACCAGTGCACAGATGTGGTGGATGGGGAGGGCCGCACGGGCCAGAAGTTCTCCCTGTGTATTCTGACGC CTGAGAAGGAGCATTTCATCCGGGCGGAGACCAAGGAGATCGTCAGTGGGTGGCTGGAGATGCTCATGGTCTATCCCCGGACCAACAAGC AGAATCAGAAGAAGAAACGGAAAGTGGAGCCCCCCACACCACAGGAGCCTGGGCCTGCCAAGGTGGCTGTTACCAGCAGCAGCAGCAGCA GCAGCAGCAGCAGCAGCATCCCCAGTGCTGAGAAAGTCCCCACCACCAAGTCCACACTCTGGCAGGAAGAAATGAGGACCAAGGACCAGC CAGATGGCAGCAGCCTGAGTCCAGCTCAGAGTCCCAGCCAGAGCCAGCCTCCTGCTGCCAGCTCCCTGCGGGAACCTGGGCTAGAGAGCA AAGAAGAGGAGAGCGCCATGAGTAGCGACCGCATGGACTGTGGCCGCAAAGTCCGGGTGGAGAGCGGCTACTTCTCTCTGGAGAAGACCA AACAGGACTTGAAGGCTGAAGAACAGCAGCTGCCCCCGCCGCTCTCCCCTCCCAGCCCCAGCACCCCCAACCACAGGAGGTCCCAGGTGA TTGAAAAGTTTGAGGCCTTGGACATTGAGAAGGCAGAGCACATGGAGACCAATGCAGTGGGGCCCTCACCATCCAGCGACACACGCCAGG GCCGCAGCGAGAAGAGGGCGTTCCCTAGGAAGCGGCCCGACCTGCTGAATTTCAAGAAAGGCTGGCTGACTAAGCAGTATGAGGACGGCC AGTGGAAGAAACACTGGTTTGTCCTCGCCGATCAAAGCCTGAGATACTACAGGGATTCAGTGGCTGAGGAGGCAGCCGACTTGGATGGAG AAATTGACTTGTCCGCATGTTACGATGTCACAGAGTATCCAGTTCAGAGAAACTATGGCTTCCAGATACATACAAAGGAGGGCGAGTTTA CCCTGTCGGCCATGACATCTGGGATTCGGCGGAACTGGATCCAGACCATCATGAAGCACGTGCACCCGACCACTGCCCCGGATGTGACCA GCTCGTTGCCAGAGGAAAAAAACAAGAGCAGCTGCTCTTTTGAGACCTGCCCGAGGCCTACTGAGAAGCAAGAGGCAGAGCTGGGGGAGC CGGACCCTGAGCAGAAGAGGAGCCGCGCACGGGAGCGGAGGCGAGAGGGCCGCTCCAAGACCTTTGACTGGGCTGAGTTCCGTCCCATCC AGCAGGCCCTGGCTCAGGAGCGGGTGGGCGGCGTGGGGCCTGCTGACACCCACGAGCCCCTGCGCCCTGAGGCGGAGCCTGGGGAGCTGG AGCGGGAGCGTGCACGGAGGCGGGAGGAGCGCCGCAAGCGCTTCGGGATGCTCGACGCCACAGACGGGCCAGGCACTGAGGATGCAGCCC TGCGCATGGAGGTGGACCGGAGCCCAGGGCTGCCTATGAGCGACCTCAAAACGCATAACGTCCACGTGGAGATTGAGCAGCGGTGGCATC AGGTGGAGACCACACCTCTCCGGGAAGAGAAGCAGGTGCCCATCGCCCCCGTCCACCTGTCTTCTGAAGATGGGGGTGACCGGCTCTCCA CACACGAGCTGACCTCTCTGCTCGAGAAGGAGCTGGAGCAGAGCCAGAAGGAGGCCTCAGACCTTCTGGAGCAGAACCGGCTCCTGCAGG ACCAGCTGAGGGTGGCCCTGGGCCGGGAGCAGAGCGCCCGTGAGGGCTACGTGCTGCAGGCCACGTGCGAGCGAGGGTTTGCAGCAATGG AAGAAACGCACCAGAAGAAGATTGAAGATCTCCAGAGGCAGCACCAGCGGGAGCTAGAGAAACTTCGAGAAGAGAAAGACCGCCTCCTAG CCGAGGAGACAGCGGCCACCATCTCAGCCATCGAAGCCATGAAGAACGCCCACCGGGAGGAAATGGAGCGGGAGCTGGAGAAGAGCCAGC GGTCCCAGATCAGCAGCGTCAACTCGGATGTTGAGGCCCTGCGGCGCCAGTACCTGGAGGAGCTGCAGTCGGTGCAGCGGGAACTGGAGG TCCTCTCGGAGCAGTACTCGCAGAAGTGCCTGGAGAATGCCCATCTGGCCCAGGCGCTGGAGGCCGAGCGGCAGGCCCTGCGGCAGTGCC AGCGTGAGAACCAGGAGCTCAATGCCCACAACCAGGAGCTGAACAACCGCCTGGCTGCAGAGATCACACGGTTGCGGACGCTGCTGACTG GGGACGGCGGTGGGGAGGCCACTGGGTCACCCCTTGCACAGGGCAAGGATGCCTATGAACTAGAGGTCTTATTGCGGGTAAAGGAATCGG AAATACAGTACCTGAAACAGGAGATTAGCTCCCTCAAGGATGAGCTGCAGACGGCACTGCGGGACAAGAAGTACGCAAGTGACAAGTACA AAGACATCTACACAGAGCTCAGCATCGCGAAGGCTAAGGCTGACTGTGACATCAGCAGGTTGAAGGAGCAGCTCAAGGCTGCAACGGAAG CACTGGGGGAGAAGTCCCCTGACAGTGCCACGGTGTCCGGATATGATATAATGAAATCTAAAAGCAACCCTGACTTCTTGAAGAAAGACA GATCCTGTGTCACCCGGCAACTCAGAAACATCAGGTCCAAGGATGCAATTCGAAGTCACAGCGAATCAGCCTCACCTTCAGCCCTGTCCA GTAGCCCCAACAATCTGAGCCCAACAGGCTGGTCACAGCCGAAAACCCCCGTGCCAGCACAAAGAGAGCGGGCACCAGTATCTGGGACCC AGGAGAAAAACAAAATTAGGCCTCGTGGACAGAGAGATTCAAGCTATTATTGGGAAATAGAAGCCAGTGAAGTGATGCTGTCCACTCGGA TTGGGTCAGGCTCTTTTGGAACTGTTTATAAGGGTAAATGGCACGGAGATGTTGCAGTAAAGATCCTAAAGGTTGTCGACCCAACCCCAG AGCAATTCCAGGCCTTCAGGAATGAGGTGGCTGTTCTGCGCAAAACACGGCATGTGAACATTCTGCTTTTCATGGGGTACATGACAAAGG ACAACCTGGCAATTGTGACCCAGTGGTGCGAGGGCAGCAGCCTCTACAAACACCTGCATGTCCAGGAGACCAAGTTTCAGATGTTCCAGC TAATTGACATTGCCCGGCAGACGGCTCAGGGAATGGACTATTTGCATGCAAAGAACATCATCCATAGAGACATGAAATCCAACAATATAT TTCTCCATGAAGGCTTAACAGTGAAAATTGGAGATTTTGGTTTGGCAACAGTAAAGTCACGCTGGAGTGGTTCTCAGCAGGTTGAACAAC CTACTGGCTCTGTCCTCTGGATGGCCCCAGAGGTGATCCGAATGCAGGATAACAACCCATTCAGTTTCCAGTCGGATGTCTACTCCTATG GCATCGTATTGTATGAACTGATGACGGGGGAGCTTCCTTATTCTCACATCAACAACCGAGATCAGATCATCTTCATGGTGGGCCGAGGAT ATGCCTCCCCAGATCTTAGTAAGCTATATAAGAACTGCCCCAAAGCAATGAAGAGGCTGGTAGCTGACTGTGTGAAGAAAGTAAAGGAAG AGAGGCCTCTTTTTCCCCAGATCCTGTCTTCCATTGAGCTGCTCCAACACTCTCTACCGAAGATCAACCGGAGCGCTTCCGAGCCATCCT TGCATCGGGCAGCCCACACTGAGGATATCAATGCTTGCACGCTGACCACGTCCCCGAGGCTGCCTGTCTTCTAGTTGACTTTGCACCTGT CTTCAGGCTGCCAGGGGAGGAGGAGAAGCCAGCAGGCACCACTTTTCTGCTCCCTTTCTCCAGAGGCAGAACACATGTTTTCAGAGAAGC TGCTGCTAAGGACCTTCTAGACTGCTCACAGGGCCTTAACTTCATGTTGCCTTCTTTTCTATCCCTTTGGGCCCTGGGAGAAGGAAGCCA >In-frame_ENST00000444976_ENST00000534997_TCGA-D9-A4Z6-06A_MPRIP_chr17_17083402_+_RAF1_chr3_12641914_length(amino acids)=1347AA_start in transcript=80_stop in transcript=4123 MSAAKENPCRKFQANIFNKSKCQNCFKPRESHLLNDEDLTQAKPIYGGWLLLAPDGTDFDNPVHRSRKWQRRFFILYEHGLLRYALDEMP TTLPQGTINMNQCTDVVDGEGRTGQKFSLCILTPEKEHFIRAETKEIVSGWLEMLMVYPRTNKQNQKKKRKVEPPTPQEPGPAKVAVTSS SSSSSSSSSIPSAEKVPTTKSTLWQEEMRTKDQPDGSSLSPAQSPSQSQPPAASSLREPGLESKEEESAMSSDRMDCGRKVRVESGYFSL EKTKQDLKAEEQQLPPPLSPPSPSTPNHRRSQVIEKFEALDIEKAEHMETNAVGPSPSSDTRQGRSEKRAFPRKRPDLLNFKKGWLTKQY EDGQWKKHWFVLADQSLRYYRDSVAEEAADLDGEIDLSACYDVTEYPVQRNYGFQIHTKEGEFTLSAMTSGIRRNWIQTIMKHVHPTTAP DVTSSLPEEKNKSSCSFETCPRPTEKQEAELGEPDPEQKRSRARERRREGRSKTFDWAEFRPIQQALAQERVGGVGPADTHEPLRPEAEP GELERERARRREERRKRFGMLDATDGPGTEDAALRMEVDRSPGLPMSDLKTHNVHVEIEQRWHQVETTPLREEKQVPIAPVHLSSEDGGD RLSTHELTSLLEKELEQSQKEASDLLEQNRLLQDQLRVALGREQSAREGYVLQATCERGFAAMEETHQKKIEDLQRQHQRELEKLREEKD RLLAEETAATISAIEAMKNAHREEMERELEKSQRSQISSVNSDVEALRRQYLEELQSVQRELEVLSEQYSQKCLENAHLAQALEAERQAL RQCQRENQELNAHNQELNNRLAAEITRLRTLLTGDGGGEATGSPLAQGKDAYELEVLLRVKESEIQYLKQEISSLKDELQTALRDKKYAS DKYKDIYTELSIAKAKADCDISRLKEQLKAATEALGEKSPDSATVSGYDIMKSKSNPDFLKKDRSCVTRQLRNIRSKDAIRSHSESASPS ALSSSPNNLSPTGWSQPKTPVPAQRERAPVSGTQEKNKIRPRGQRDSSYYWEIEASEVMLSTRIGSGSFGTVYKGKWHGDVAVKILKVVD PTPEQFQAFRNEVAVLRKTRHVNILLFMGYMTKDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKS NNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSDVYSYGIVLYELMTGELPYSHINNRDQIIFMV -------------------------------------------------------------- >In-frame_ENST00000444976_ENST00000542177_TCGA-D9-A4Z6-06A_MPRIP_chr17_17083402_+_RAF1_chr3_12641914_length(transcript)=4305nt_BP=3011nt CTGAGCCCCTAGCCCGCCGGGAGCGCCAGGCCGGCCAGGCCTGCGCCGCCGCCGCCGCCGCCGTCGCCGCCGCGCCGACCATGTCGGCAG CCAAGGAGAACCCGTGCAGGAAATTCCAGGCCAACATCTTCAACAAGAGCAAGTGTCAGAACTGCTTCAAGCCCCGCGAGTCGCATCTGC TCAACGACGAGGACCTGACGCAGGCAAAACCCATTTATGGCGGTTGGCTGCTCCTGGCTCCAGATGGGACCGACTTTGACAACCCAGTGC ACCGGTCTCGGAAATGGCAGCGACGGTTCTTCATCCTTTACGAGCACGGCCTCTTGCGCTACGCCCTGGATGAGATGCCCACGACCCTTC CTCAGGGCACCATCAACATGAACCAGTGCACAGATGTGGTGGATGGGGAGGGCCGCACGGGCCAGAAGTTCTCCCTGTGTATTCTGACGC CTGAGAAGGAGCATTTCATCCGGGCGGAGACCAAGGAGATCGTCAGTGGGTGGCTGGAGATGCTCATGGTCTATCCCCGGACCAACAAGC AGAATCAGAAGAAGAAACGGAAAGTGGAGCCCCCCACACCACAGGAGCCTGGGCCTGCCAAGGTGGCTGTTACCAGCAGCAGCAGCAGCA GCAGCAGCAGCAGCAGCATCCCCAGTGCTGAGAAAGTCCCCACCACCAAGTCCACACTCTGGCAGGAAGAAATGAGGACCAAGGACCAGC CAGATGGCAGCAGCCTGAGTCCAGCTCAGAGTCCCAGCCAGAGCCAGCCTCCTGCTGCCAGCTCCCTGCGGGAACCTGGGCTAGAGAGCA AAGAAGAGGAGAGCGCCATGAGTAGCGACCGCATGGACTGTGGCCGCAAAGTCCGGGTGGAGAGCGGCTACTTCTCTCTGGAGAAGACCA AACAGGACTTGAAGGCTGAAGAACAGCAGCTGCCCCCGCCGCTCTCCCCTCCCAGCCCCAGCACCCCCAACCACAGGAGGTCCCAGGTGA TTGAAAAGTTTGAGGCCTTGGACATTGAGAAGGCAGAGCACATGGAGACCAATGCAGTGGGGCCCTCACCATCCAGCGACACACGCCAGG GCCGCAGCGAGAAGAGGGCGTTCCCTAGGAAGCGGCCCGACCTGCTGAATTTCAAGAAAGGCTGGCTGACTAAGCAGTATGAGGACGGCC AGTGGAAGAAACACTGGTTTGTCCTCGCCGATCAAAGCCTGAGATACTACAGGGATTCAGTGGCTGAGGAGGCAGCCGACTTGGATGGAG AAATTGACTTGTCCGCATGTTACGATGTCACAGAGTATCCAGTTCAGAGAAACTATGGCTTCCAGATACATACAAAGGAGGGCGAGTTTA CCCTGTCGGCCATGACATCTGGGATTCGGCGGAACTGGATCCAGACCATCATGAAGCACGTGCACCCGACCACTGCCCCGGATGTGACCA GCTCGTTGCCAGAGGAAAAAAACAAGAGCAGCTGCTCTTTTGAGACCTGCCCGAGGCCTACTGAGAAGCAAGAGGCAGAGCTGGGGGAGC CGGACCCTGAGCAGAAGAGGAGCCGCGCACGGGAGCGGAGGCGAGAGGGCCGCTCCAAGACCTTTGACTGGGCTGAGTTCCGTCCCATCC AGCAGGCCCTGGCTCAGGAGCGGGTGGGCGGCGTGGGGCCTGCTGACACCCACGAGCCCCTGCGCCCTGAGGCGGAGCCTGGGGAGCTGG AGCGGGAGCGTGCACGGAGGCGGGAGGAGCGCCGCAAGCGCTTCGGGATGCTCGACGCCACAGACGGGCCAGGCACTGAGGATGCAGCCC TGCGCATGGAGGTGGACCGGAGCCCAGGGCTGCCTATGAGCGACCTCAAAACGCATAACGTCCACGTGGAGATTGAGCAGCGGTGGCATC AGGTGGAGACCACACCTCTCCGGGAAGAGAAGCAGGTGCCCATCGCCCCCGTCCACCTGTCTTCTGAAGATGGGGGTGACCGGCTCTCCA CACACGAGCTGACCTCTCTGCTCGAGAAGGAGCTGGAGCAGAGCCAGAAGGAGGCCTCAGACCTTCTGGAGCAGAACCGGCTCCTGCAGG ACCAGCTGAGGGTGGCCCTGGGCCGGGAGCAGAGCGCCCGTGAGGGCTACGTGCTGCAGGCCACGTGCGAGCGAGGGTTTGCAGCAATGG AAGAAACGCACCAGAAGAAGATTGAAGATCTCCAGAGGCAGCACCAGCGGGAGCTAGAGAAACTTCGAGAAGAGAAAGACCGCCTCCTAG CCGAGGAGACAGCGGCCACCATCTCAGCCATCGAAGCCATGAAGAACGCCCACCGGGAGGAAATGGAGCGGGAGCTGGAGAAGAGCCAGC GGTCCCAGATCAGCAGCGTCAACTCGGATGTTGAGGCCCTGCGGCGCCAGTACCTGGAGGAGCTGCAGTCGGTGCAGCGGGAACTGGAGG TCCTCTCGGAGCAGTACTCGCAGAAGTGCCTGGAGAATGCCCATCTGGCCCAGGCGCTGGAGGCCGAGCGGCAGGCCCTGCGGCAGTGCC AGCGTGAGAACCAGGAGCTCAATGCCCACAACCAGGAGCTGAACAACCGCCTGGCTGCAGAGATCACACGGTTGCGGACGCTGCTGACTG GGGACGGCGGTGGGGAGGCCACTGGGTCACCCCTTGCACAGGGCAAGGATGCCTATGAACTAGAGGTCTTATTGCGGGTAAAGGAATCGG AAATACAGTACCTGAAACAGGAGATTAGCTCCCTCAAGGATGAGCTGCAGACGGCACTGCGGGACAAGAAGTACGCAAGTGACAAGTACA AAGACATCTACACAGAGCTCAGCATCGCGAAGGCTAAGGCTGACTGTGACATCAGCAGGTTGAAGGAGCAGCTCAAGGCTGCAACGGAAG CACTGGGGGAGAAGTCCCCTGACAGTGCCACGGTGTCCGGATATGATATAATGAAATCTAAAAGCAACCCTGACTTCTTGAAGAAAGACA GATCCTGTGTCACCCGGCAACTCAGAAACATCAGGTCCAAGGATGCAATTCGAAGTCACAGCGAATCAGCCTCACCTTCAGCCCTGTCCA GTAGCCCCAACAATCTGAGCCCAACAGGCTGGTCACAGCCGAAAACCCCCGTGCCAGCACAAAGAGAGCGGGCACCAGTATCTGGGACCC AGGAGAAAAACAAAATTAGGCCTCGTGGACAGAGAGATTCAAGCTATTATTGGGAAATAGAAGCCAGTGAAGTGATGCTGTCCACTCGGA TTGGGTCAGGCTCTTTTGGAACTGTTTATAAGGGTAAATGGCACGGAGATGTTGCAGTAAAGATCCTAAAGGTTGTCGACCCAACCCCAG AGCAATTCCAGGCCTTCAGGAATGAGGTGGCTGTTCTGCGCAAAACACGGCATGTGAACATTCTGCTTTTCATGGGGTACATGACAAAGG ACAACCTGGCAATTGTGACCCAGTGGTGCGAGGGCAGCAGCCTCTACAAACACCTGCATGTCCAGGAGACCAAGTTTCAGATGTTCCAGC TAATTGACATTGCCCGGCAGACGGCTCAGGGAATGGACTATTTGCATGCAAAGAACATCATCCATAGAGACATGAAATCCAACAATATAT TTCTCCATGAAGGCTTAACAGTGAAAATTGGAGATTTTGGTTTGGCAACAGTAAAGTCACGCTGGAGTGGTTCTCAGCAGGTTGAACAAC CTACTGGCTCTGTCCTCTGGATGGCCCCAGAGGTGATCCGAATGCAGGATAACAACCCATTCAGTTTCCAGTCGGATGTCTACTCCTATG GCATCGTATTGTATGAACTGATGACGGGGGAGCTTCCTTATTCTCACATCAACAACCGAGATCAGATCATCTTCATGGTGGGCCGAGGAT ATGCCTCCCCAGATCTTAGTAAGCTATATAAGAACTGCCCCAAAGCAATGAAGAGGCTGGTAGCTGACTGTGTGAAGAAAGTAAAGGAAG AGAGGCCTCTTTTTCCCCAGATCCTGTCTTCCATTGAGCTGCTCCAACACTCTCTACCGAAGATCAACCGGAGCGCTTCCGAGCCATCCT TGCATCGGGCAGCCCACACTGAGGATATCAATGCTTGCACGCTGACCACGTCCCCGAGGCTGCCTGTCTTCTAGTTGACTTTGCACCTGT CTTCAGGCTGCCAGGGGAGGAGGAGAAGCCAGCAGGCACCACTTTTCTGCTCCCTTTCTCCAGAGGCAGAACACATGTTTTCAGAGAAGC >In-frame_ENST00000444976_ENST00000542177_TCGA-D9-A4Z6-06A_MPRIP_chr17_17083402_+_RAF1_chr3_12641914_length(amino acids)=1347AA_start in transcript=80_stop in transcript=4123 MSAAKENPCRKFQANIFNKSKCQNCFKPRESHLLNDEDLTQAKPIYGGWLLLAPDGTDFDNPVHRSRKWQRRFFILYEHGLLRYALDEMP TTLPQGTINMNQCTDVVDGEGRTGQKFSLCILTPEKEHFIRAETKEIVSGWLEMLMVYPRTNKQNQKKKRKVEPPTPQEPGPAKVAVTSS SSSSSSSSSIPSAEKVPTTKSTLWQEEMRTKDQPDGSSLSPAQSPSQSQPPAASSLREPGLESKEEESAMSSDRMDCGRKVRVESGYFSL EKTKQDLKAEEQQLPPPLSPPSPSTPNHRRSQVIEKFEALDIEKAEHMETNAVGPSPSSDTRQGRSEKRAFPRKRPDLLNFKKGWLTKQY EDGQWKKHWFVLADQSLRYYRDSVAEEAADLDGEIDLSACYDVTEYPVQRNYGFQIHTKEGEFTLSAMTSGIRRNWIQTIMKHVHPTTAP DVTSSLPEEKNKSSCSFETCPRPTEKQEAELGEPDPEQKRSRARERRREGRSKTFDWAEFRPIQQALAQERVGGVGPADTHEPLRPEAEP GELERERARRREERRKRFGMLDATDGPGTEDAALRMEVDRSPGLPMSDLKTHNVHVEIEQRWHQVETTPLREEKQVPIAPVHLSSEDGGD RLSTHELTSLLEKELEQSQKEASDLLEQNRLLQDQLRVALGREQSAREGYVLQATCERGFAAMEETHQKKIEDLQRQHQRELEKLREEKD RLLAEETAATISAIEAMKNAHREEMERELEKSQRSQISSVNSDVEALRRQYLEELQSVQRELEVLSEQYSQKCLENAHLAQALEAERQAL RQCQRENQELNAHNQELNNRLAAEITRLRTLLTGDGGGEATGSPLAQGKDAYELEVLLRVKESEIQYLKQEISSLKDELQTALRDKKYAS DKYKDIYTELSIAKAKADCDISRLKEQLKAATEALGEKSPDSATVSGYDIMKSKSNPDFLKKDRSCVTRQLRNIRSKDAIRSHSESASPS ALSSSPNNLSPTGWSQPKTPVPAQRERAPVSGTQEKNKIRPRGQRDSSYYWEIEASEVMLSTRIGSGSFGTVYKGKWHGDVAVKILKVVD PTPEQFQAFRNEVAVLRKTRHVNILLFMGYMTKDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKS NNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSDVYSYGIVLYELMTGELPYSHINNRDQIIFMV -------------------------------------------------------------- >In-frame_ENST00000395804_ENST00000251849_TCGA-D9-A4Z6-06A_MPRIP_chr17_17083402_+_RAF1_chr3_12641914_length(transcript)=5127nt_BP=3101nt GCCAGGCCGGCCAGGCCTGCGCCGCCGCCGCCGCCGCCGTCGCCGCCGCGCCGACCATGTCGGCAGCCAAGGAGAACCCGTGCAGGAAAT TCCAGGCCAACATCTTCAACAAGAGCAAGTGTCAGAACTGCTTCAAGCCCCGCGAGTCGCATCTGCTCAACGACGAGGACCTGACGCAGG CAAAACCCATTTATGGCGGTTGGCTGCTCCTGGCTCCAGATGGGACCGACTTTGACAACCCAGTGCACCGGTCTCGGAAATGGCAGCGAC GGTTCTTCATCCTTTACGAGCACGGCCTCTTGCGCTACGCCCTGGATGAGATGCCCACGACCCTTCCTCAGGGCACCATCAACATGAACC AGTGCACAGATGTGGTGGATGGGGAGGGCCGCACGGGCCAGAAGTTCTCCCTGTGTATTCTGACGCCTGAGAAGGAGCATTTCATCCGGG CGGAGACCAAGGAGATCGTCAGTGGGTGGCTGGAGATGCTCATGGTCTATCCCCGGACCAACAAGCAGAATCAGAAGAAGAAACGGAAAG TGGAGCCCCCCACACCACAGGAGCCTGGGCCTGCCAAGGTGGCTGTTACCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCATCCCCA GTGCTGAGAAAGTCCCCACCACCAAGTCCACACTCTGGCAGGAAGAAATGAGGACCAAGGACCAGCCAGATGGCAGCAGCCTGAGTCCAG CTCAGAGTCCCAGCCAGAGCCAGCCTCCTGCTGCCAGCTCCCTGCGGGAACCTGGGCTAGAGAGCAAAGAAGAGGAGAGCGCCATGAGTA GCGACCGCATGGACTGTGGCCGCAAAGTCCGGGTGGAGAGCGGCTACTTCTCTCTGGAGAAGACCAAACAGGACTTGAAGGCTGAAGAAC AGCAGCTGCCCCCGCCGCTCTCCCCTCCCAGCCCCAGCACCCCCAACCACAGGAGGTCCCAGGTGATTGAAAAGTTTGAGGCCTTGGACA TTGAGAAGGCAGAGCACATGGAGACCAATGCAGTGGGGCCCTCACCATCCAGCGACACACGCCAGGGCCGCAGCGAGAAGAGGGCGTTCC CTAGGAAGCGGGACTTCACCAATGAAGCCCCCCCAGCTCCTCTCCCAGACGCCTCGGCTTCCCCCCTGTCTCCACACCGAAGAGCCAAGT CACTGGACAGGAGGTCCACGGAGCCCTCCGTGACGCCCGACCTGCTGAATTTCAAGAAAGGCTGGCTGACTAAGCAGTATGAGGACGGCC AGTGGAAGAAACACTGGTTTGTCCTCGCCGATCAAAGCCTGAGATACTACAGGGATTCAGTGGCTGAGGAGGCAGCCGACTTGGATGGAG AAATTGACTTGTCCGCATGTTACGATGTCACAGAGTATCCAGTTCAGAGAAACTATGGCTTCCAGATACATACAAAGGAGGGCGAGTTTA CCCTGTCGGCCATGACATCTGGGATTCGGCGGAACTGGATCCAGACCATCATGAAGCACGTGCACCCGACCACTGCCCCGGATGTGACCA GCTCGTTGCCAGAGGAAAAAAACAAGAGCAGCTGCTCTTTTGAGACCTGCCCGAGGCCTACTGAGAAGCAAGAGGCAGAGCTGGGGGAGC CGGACCCTGAGCAGAAGAGGAGCCGCGCACGGGAGCGGAGGCGAGAGGGCCGCTCCAAGACCTTTGACTGGGCTGAGTTCCGTCCCATCC AGCAGGCCCTGGCTCAGGAGCGGGTGGGCGGCGTGGGGCCTGCTGACACCCACGAGCCCCTGCGCCCTGAGGCGGAGCCTGGGGAGCTGG AGCGGGAGCGTGCACGGAGGCGGGAGGAGCGCCGCAAGCGCTTCGGGATGCTCGACGCCACAGACGGGCCAGGCACTGAGGATGCAGCCC TGCGCATGGAGGTGGACCGGAGCCCAGGGCTGCCTATGAGCGACCTCAAAACGCATAACGTCCACGTGGAGATTGAGCAGCGGTGGCATC AGGTGGAGACCACACCTCTCCGGGAAGAGAAGCAGGTGCCCATCGCCCCCGTCCACCTGTCTTCTGAAGATGGGGGTGACCGGCTCTCCA CACACGAGCTGACCTCTCTGCTCGAGAAGGAGCTGGAGCAGAGCCAGAAGGAGGCCTCAGACCTTCTGGAGCAGAACCGGCTCCTGCAGG ACCAGCTGAGGGTGGCCCTGGGCCGGGAGCAGAGCGCCCGTGAGGGCTACGTGCTGCAGGCCACGTGCGAGCGAGGGTTTGCAGCAATGG AAGAAACGCACCAGAAGAAGATTGAAGATCTCCAGAGGCAGCACCAGCGGGAGCTAGAGAAACTTCGAGAAGAGAAAGACCGCCTCCTAG CCGAGGAGACAGCGGCCACCATCTCAGCCATCGAAGCCATGAAGAACGCCCACCGGGAGGAAATGGAGCGGGAGCTGGAGAAGAGCCAGC GGTCCCAGATCAGCAGCGTCAACTCGGATGTTGAGGCCCTGCGGCGCCAGTACCTGGAGGAGCTGCAGTCGGTGCAGCGGGAACTGGAGG TCCTCTCGGAGCAGTACTCGCAGAAGTGCCTGGAGAATGCCCATCTGGCCCAGGCGCTGGAGGCCGAGCGGCAGGCCCTGCGGCAGTGCC AGCGTGAGAACCAGGAGCTCAATGCCCACAACCAGGAGCTGAACAACCGCCTGGCTGCAGAGATCACACGGTTGCGGACGCTGCTGACTG GGGACGGCGGTGGGGAGGCCACTGGGTCACCCCTTGCACAGGGCAAGGATGCCTATGAACTAGAGGTCTTATTGCGGGTAAAGGAATCGG AAATACAGTACCTGAAACAGGAGATTAGCTCCCTCAAGGATGAGCTGCAGACGGCACTGCGGGACAAGAAGTACGCAAGTGACAAGTACA AAGACATCTACACAGAGCTCAGCATCGCGAAGGCTAAGGCTGACTGTGACATCAGCAGGTTGAAGGAGCAGCTCAAGGCTGCAACGGAAG CACTGGGGGAGAAGTCCCCTGACAGTGCCACGGTGTCCGGATATGATATAATGAAATCTAAAAGCAACCCTGACTTCTTGAAGAAAGACA GATCCTGTGTCACCCGGCAACTCAGAAACATCAGGTCCAAGGATGCAATTCGAAGTCACAGCGAATCAGCCTCACCTTCAGCCCTGTCCA GTAGCCCCAACAATCTGAGCCCAACAGGCTGGTCACAGCCGAAAACCCCCGTGCCAGCACAAAGAGAGCGGGCACCAGTATCTGGGACCC AGGAGAAAAACAAAATTAGGCCTCGTGGACAGAGAGATTCAAGCTATTATTGGGAAATAGAAGCCAGTGAAGTGATGCTGTCCACTCGGA TTGGGTCAGGCTCTTTTGGAACTGTTTATAAGGGTAAATGGCACGGAGATGTTGCAGTAAAGATCCTAAAGGTTGTCGACCCAACCCCAG AGCAATTCCAGGCCTTCAGGAATGAGGTGGCTGTTCTGCGCAAAACACGGCATGTGAACATTCTGCTTTTCATGGGGTACATGACAAAGG ACAACCTGGCAATTGTGACCCAGTGGTGCGAGGGCAGCAGCCTCTACAAACACCTGCATGTCCAGGAGACCAAGTTTCAGATGTTCCAGC TAATTGACATTGCCCGGCAGACGGCTCAGGGAATGGACTATTTGCATGCAAAGAACATCATCCATAGAGACATGAAATCCAACAATATAT TTCTCCATGAAGGCTTAACAGTGAAAATTGGAGATTTTGGTTTGGCAACAGTAAAGTCACGCTGGAGTGGTTCTCAGCAGGTTGAACAAC CTACTGGCTCTGTCCTCTGGATGGCCCCAGAGGTGATCCGAATGCAGGATAACAACCCATTCAGTTTCCAGTCGGATGTCTACTCCTATG GCATCGTATTGTATGAACTGATGACGGGGGAGCTTCCTTATTCTCACATCAACAACCGAGATCAGATCATCTTCATGGTGGGCCGAGGAT ATGCCTCCCCAGATCTTAGTAAGCTATATAAGAACTGCCCCAAAGCAATGAAGAGGCTGGTAGCTGACTGTGTGAAGAAAGTAAAGGAAG AGAGGCCTCTTTTTCCCCAGATCCTGTCTTCCATTGAGCTGCTCCAACACTCTCTACCGAAGATCAACCGGAGCGCTTCCGAGCCATCCT TGCATCGGGCAGCCCACACTGAGGATATCAATGCTTGCACGCTGACCACGTCCCCGAGGCTGCCTGTCTTCTAGTTGACTTTGCACCTGT CTTCAGGCTGCCAGGGGAGGAGGAGAAGCCAGCAGGCACCACTTTTCTGCTCCCTTTCTCCAGAGGCAGAACACATGTTTTCAGAGAAGC TGCTGCTAAGGACCTTCTAGACTGCTCACAGGGCCTTAACTTCATGTTGCCTTCTTTTCTATCCCTTTGGGCCCTGGGAGAAGGAAGCCA TTTGCAGTGCTGGTGTGTCCTGCTCCCTCCCCACATTCCCCATGCTCAAGGCCCAGCCTTCTGTAGATGCGCAAGTGGATGTTGATGGTA GTACAAAAAGCAGGGGCCCAGCCCCAGCTGTTGGCTACATGAGTATTTAGAGGAAGTAAGGTAGCAGGCAGTCCAGCCCTGATGTGGAGA CACATGGGATTTTGGAAATCAGCTTCTGGAGGAATGCATGTCACAGGCGGGACTTTCTTCAGAGAGTGGTGCAGCGCCAGACATTTTGCA CATAAGGCACCAAACAGCCCAGGACTGCCGAGACTCTGGCCGCCCGAAGGAGCCTGCTTTGGTACTATGGAACTTTTCTTAGGGGACACG TCCTCCTTTCACAGCTTCTAAGGTGTCCAGTGCATTGGGATGGTTTTCCAGGCAAGGCACTCGGCCAATCCGCATCTCAGCCCTCTCAGG GAGCAGTCTTCCATCATGCTGAATTTTGTCTTCCAGGAGCTGCCCCTATGGGGCGGGGCCGCAGGGCCAGCCTTGTTTCTCTAACAAACA AACAAACAAACAGCCTTGTTTCTCTAGTCACATCATGTGTATACAAGGAAGCCAGGAATACAGGTTTTCTTGATGATTTGGGTTTTAATT >In-frame_ENST00000395804_ENST00000251849_TCGA-D9-A4Z6-06A_MPRIP_chr17_17083402_+_RAF1_chr3_12641914_length(amino acids)=1385AA_start in transcript=56_stop in transcript=4213 MSAAKENPCRKFQANIFNKSKCQNCFKPRESHLLNDEDLTQAKPIYGGWLLLAPDGTDFDNPVHRSRKWQRRFFILYEHGLLRYALDEMP TTLPQGTINMNQCTDVVDGEGRTGQKFSLCILTPEKEHFIRAETKEIVSGWLEMLMVYPRTNKQNQKKKRKVEPPTPQEPGPAKVAVTSS SSSSSSSSSIPSAEKVPTTKSTLWQEEMRTKDQPDGSSLSPAQSPSQSQPPAASSLREPGLESKEEESAMSSDRMDCGRKVRVESGYFSL EKTKQDLKAEEQQLPPPLSPPSPSTPNHRRSQVIEKFEALDIEKAEHMETNAVGPSPSSDTRQGRSEKRAFPRKRDFTNEAPPAPLPDAS ASPLSPHRRAKSLDRRSTEPSVTPDLLNFKKGWLTKQYEDGQWKKHWFVLADQSLRYYRDSVAEEAADLDGEIDLSACYDVTEYPVQRNY GFQIHTKEGEFTLSAMTSGIRRNWIQTIMKHVHPTTAPDVTSSLPEEKNKSSCSFETCPRPTEKQEAELGEPDPEQKRSRARERRREGRS KTFDWAEFRPIQQALAQERVGGVGPADTHEPLRPEAEPGELERERARRREERRKRFGMLDATDGPGTEDAALRMEVDRSPGLPMSDLKTH NVHVEIEQRWHQVETTPLREEKQVPIAPVHLSSEDGGDRLSTHELTSLLEKELEQSQKEASDLLEQNRLLQDQLRVALGREQSAREGYVL QATCERGFAAMEETHQKKIEDLQRQHQRELEKLREEKDRLLAEETAATISAIEAMKNAHREEMERELEKSQRSQISSVNSDVEALRRQYL EELQSVQRELEVLSEQYSQKCLENAHLAQALEAERQALRQCQRENQELNAHNQELNNRLAAEITRLRTLLTGDGGGEATGSPLAQGKDAY ELEVLLRVKESEIQYLKQEISSLKDELQTALRDKKYASDKYKDIYTELSIAKAKADCDISRLKEQLKAATEALGEKSPDSATVSGYDIMK SKSNPDFLKKDRSCVTRQLRNIRSKDAIRSHSESASPSALSSSPNNLSPTGWSQPKTPVPAQRERAPVSGTQEKNKIRPRGQRDSSYYWE IEASEVMLSTRIGSGSFGTVYKGKWHGDVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYMTKDNLAIVTQWCEGSSLYKHL HVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNN PFSFQSDVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCVKKVKEERPLFPQILSSIELLQHSL -------------------------------------------------------------- >In-frame_ENST00000395804_ENST00000442415_TCGA-D9-A4Z6-06A_MPRIP_chr17_17083402_+_RAF1_chr3_12641914_length(transcript)=4930nt_BP=3101nt GCCAGGCCGGCCAGGCCTGCGCCGCCGCCGCCGCCGCCGTCGCCGCCGCGCCGACCATGTCGGCAGCCAAGGAGAACCCGTGCAGGAAAT TCCAGGCCAACATCTTCAACAAGAGCAAGTGTCAGAACTGCTTCAAGCCCCGCGAGTCGCATCTGCTCAACGACGAGGACCTGACGCAGG CAAAACCCATTTATGGCGGTTGGCTGCTCCTGGCTCCAGATGGGACCGACTTTGACAACCCAGTGCACCGGTCTCGGAAATGGCAGCGAC GGTTCTTCATCCTTTACGAGCACGGCCTCTTGCGCTACGCCCTGGATGAGATGCCCACGACCCTTCCTCAGGGCACCATCAACATGAACC AGTGCACAGATGTGGTGGATGGGGAGGGCCGCACGGGCCAGAAGTTCTCCCTGTGTATTCTGACGCCTGAGAAGGAGCATTTCATCCGGG CGGAGACCAAGGAGATCGTCAGTGGGTGGCTGGAGATGCTCATGGTCTATCCCCGGACCAACAAGCAGAATCAGAAGAAGAAACGGAAAG TGGAGCCCCCCACACCACAGGAGCCTGGGCCTGCCAAGGTGGCTGTTACCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCATCCCCA GTGCTGAGAAAGTCCCCACCACCAAGTCCACACTCTGGCAGGAAGAAATGAGGACCAAGGACCAGCCAGATGGCAGCAGCCTGAGTCCAG CTCAGAGTCCCAGCCAGAGCCAGCCTCCTGCTGCCAGCTCCCTGCGGGAACCTGGGCTAGAGAGCAAAGAAGAGGAGAGCGCCATGAGTA GCGACCGCATGGACTGTGGCCGCAAAGTCCGGGTGGAGAGCGGCTACTTCTCTCTGGAGAAGACCAAACAGGACTTGAAGGCTGAAGAAC AGCAGCTGCCCCCGCCGCTCTCCCCTCCCAGCCCCAGCACCCCCAACCACAGGAGGTCCCAGGTGATTGAAAAGTTTGAGGCCTTGGACA TTGAGAAGGCAGAGCACATGGAGACCAATGCAGTGGGGCCCTCACCATCCAGCGACACACGCCAGGGCCGCAGCGAGAAGAGGGCGTTCC CTAGGAAGCGGGACTTCACCAATGAAGCCCCCCCAGCTCCTCTCCCAGACGCCTCGGCTTCCCCCCTGTCTCCACACCGAAGAGCCAAGT CACTGGACAGGAGGTCCACGGAGCCCTCCGTGACGCCCGACCTGCTGAATTTCAAGAAAGGCTGGCTGACTAAGCAGTATGAGGACGGCC AGTGGAAGAAACACTGGTTTGTCCTCGCCGATCAAAGCCTGAGATACTACAGGGATTCAGTGGCTGAGGAGGCAGCCGACTTGGATGGAG AAATTGACTTGTCCGCATGTTACGATGTCACAGAGTATCCAGTTCAGAGAAACTATGGCTTCCAGATACATACAAAGGAGGGCGAGTTTA CCCTGTCGGCCATGACATCTGGGATTCGGCGGAACTGGATCCAGACCATCATGAAGCACGTGCACCCGACCACTGCCCCGGATGTGACCA GCTCGTTGCCAGAGGAAAAAAACAAGAGCAGCTGCTCTTTTGAGACCTGCCCGAGGCCTACTGAGAAGCAAGAGGCAGAGCTGGGGGAGC CGGACCCTGAGCAGAAGAGGAGCCGCGCACGGGAGCGGAGGCGAGAGGGCCGCTCCAAGACCTTTGACTGGGCTGAGTTCCGTCCCATCC AGCAGGCCCTGGCTCAGGAGCGGGTGGGCGGCGTGGGGCCTGCTGACACCCACGAGCCCCTGCGCCCTGAGGCGGAGCCTGGGGAGCTGG AGCGGGAGCGTGCACGGAGGCGGGAGGAGCGCCGCAAGCGCTTCGGGATGCTCGACGCCACAGACGGGCCAGGCACTGAGGATGCAGCCC TGCGCATGGAGGTGGACCGGAGCCCAGGGCTGCCTATGAGCGACCTCAAAACGCATAACGTCCACGTGGAGATTGAGCAGCGGTGGCATC AGGTGGAGACCACACCTCTCCGGGAAGAGAAGCAGGTGCCCATCGCCCCCGTCCACCTGTCTTCTGAAGATGGGGGTGACCGGCTCTCCA CACACGAGCTGACCTCTCTGCTCGAGAAGGAGCTGGAGCAGAGCCAGAAGGAGGCCTCAGACCTTCTGGAGCAGAACCGGCTCCTGCAGG ACCAGCTGAGGGTGGCCCTGGGCCGGGAGCAGAGCGCCCGTGAGGGCTACGTGCTGCAGGCCACGTGCGAGCGAGGGTTTGCAGCAATGG AAGAAACGCACCAGAAGAAGATTGAAGATCTCCAGAGGCAGCACCAGCGGGAGCTAGAGAAACTTCGAGAAGAGAAAGACCGCCTCCTAG CCGAGGAGACAGCGGCCACCATCTCAGCCATCGAAGCCATGAAGAACGCCCACCGGGAGGAAATGGAGCGGGAGCTGGAGAAGAGCCAGC GGTCCCAGATCAGCAGCGTCAACTCGGATGTTGAGGCCCTGCGGCGCCAGTACCTGGAGGAGCTGCAGTCGGTGCAGCGGGAACTGGAGG TCCTCTCGGAGCAGTACTCGCAGAAGTGCCTGGAGAATGCCCATCTGGCCCAGGCGCTGGAGGCCGAGCGGCAGGCCCTGCGGCAGTGCC AGCGTGAGAACCAGGAGCTCAATGCCCACAACCAGGAGCTGAACAACCGCCTGGCTGCAGAGATCACACGGTTGCGGACGCTGCTGACTG GGGACGGCGGTGGGGAGGCCACTGGGTCACCCCTTGCACAGGGCAAGGATGCCTATGAACTAGAGGTCTTATTGCGGGTAAAGGAATCGG AAATACAGTACCTGAAACAGGAGATTAGCTCCCTCAAGGATGAGCTGCAGACGGCACTGCGGGACAAGAAGTACGCAAGTGACAAGTACA AAGACATCTACACAGAGCTCAGCATCGCGAAGGCTAAGGCTGACTGTGACATCAGCAGGTTGAAGGAGCAGCTCAAGGCTGCAACGGAAG CACTGGGGGAGAAGTCCCCTGACAGTGCCACGGTGTCCGGATATGATATAATGAAATCTAAAAGCAACCCTGACTTCTTGAAGAAAGACA GATCCTGTGTCACCCGGCAACTCAGAAACATCAGGTCCAAGGATGCAATTCGAAGTCACAGCGAATCAGCCTCACCTTCAGCCCTGTCCA GTAGCCCCAACAATCTGAGCCCAACAGGCTGGTCACAGCCGAAAACCCCCGTGCCAGCACAAAGAGAGCGGGCACCAGTATCTGGGACCC AGGAGAAAAACAAAATTAGGCCTCGTGGACAGAGAGATTCAAGCTATTATTGGGAAATAGAAGCCAGTGAAGTGATGCTGTCCACTCGGA TTGGGTCAGGCTCTTTTGGAACTGTTTATAAGGGTAAATGGCACGGAGATGTTGCAGTAAAGATCCTAAAGGTTGTCGACCCAACCCCAG AGCAATTCCAGGCCTTCAGGAATGAGGTGGCTGTTCTGCGCAAAACACGGCATGTGAACATTCTGCTTTTCATGGGGTACATGACAAAGG ACAACCTGGCAATTGTGACCCAGTGGTGCGAGGGCAGCAGCCTCTACAAACACCTGCATGTCCAGGAGACCAAGTTTCAGATGTTCCAGC TAATTGACATTGCCCGGCAGACGGCTCAGGGAATGGACTATTTGCATGCAAAGAACATCATCCATAGAGACATGAAATCCAACAATATAT TTCTCCATGAAGGCTTAACAGTGAAAATTGGAGATTTTGGTTTGGCAACAGTAAAGTCACGCTGGAGTGGTTCTCAGCAGGTTGAACAAC CTACTGGCTCTGTCCTCTGGATGGCCCCAGAGGTGATCCGAATGCAGGATAACAACCCATTCAGTTTCCAGTCGGATGTCTACTCCTATG GCATCGTATTGTATGAACTGATGACGGGGGAGCTTCCTTATTCTCACATCAACAACCGAGATCAGATCATCTTCATGGTGGGCCGAGGAT ATGCCTCCCCAGATCTTAGTAAGCTATATAAGAACTGCCCCAAAGCAATGAAGAGGCTGGTAGCTGACTGTGTGAAGAAAGTAAAGGAAG AGAGGCCTCTTTTTCCCCAGATCCTGTCTTCCATTGAGCTGCTCCAACACTCTCTACCGAAGATCAACCGGAGCGCTTCCGAGCCATCCT TGCATCGGGCAGCCCACACTGAGGATATCAATGCTTGCACGCTGACCACGTCCCCGAGGCTGCCTGTCTTCTAGTTGACTTTGCACCTGT CTTCAGGCTGCCAGGGGAGGAGGAGAAGCCAGCAGGCACCACTTTTCTGCTCCCTTTCTCCAGAGGCAGAACACATGTTTTCAGAGAAGC TGCTGCTAAGGACCTTCTAGACTGCTCACAGGGCCTTAACTTCATGTTGCCTTCTTTTCTATCCCTTTGGGCCCTGGGAGAAGGAAGCCA TTTGCAGTGCTGGTGTGTCCTGCTCCCTCCCCACATTCCCCATGCTCAAGGCCCAGCCTTCTGTAGATGCGCAAGTGGATGTTGATGGTA GTACAAAAAGCAGGGGCCCAGCCCCAGCTGTTGGCTACATGAGTATTTAGAGGAAGTAAGGTAGCAGGCAGTCCAGCCCTGATGTGGAGA CACATGGGATTTTGGAAATCAGCTTCTGGAGGAATGCATGTCACAGGCGGGACTTTCTTCAGAGAGTGGTGCAGCGCCAGACATTTTGCA CATAAGGCACCAAACAGCCCAGGACTGCCGAGACTCTGGCCGCCCGAAGGAGCCTGCTTTGGTACTATGGAACTTTTCTTAGGGGACACG TCCTCCTTTCACAGCTTCTAAGGTGTCCAGTGCATTGGGATGGTTTTCCAGGCAAGGCACTCGGCCAATCCGCATCTCAGCCCTCTCAGG >In-frame_ENST00000395804_ENST00000442415_TCGA-D9-A4Z6-06A_MPRIP_chr17_17083402_+_RAF1_chr3_12641914_length(amino acids)=1385AA_start in transcript=56_stop in transcript=4213 MSAAKENPCRKFQANIFNKSKCQNCFKPRESHLLNDEDLTQAKPIYGGWLLLAPDGTDFDNPVHRSRKWQRRFFILYEHGLLRYALDEMP TTLPQGTINMNQCTDVVDGEGRTGQKFSLCILTPEKEHFIRAETKEIVSGWLEMLMVYPRTNKQNQKKKRKVEPPTPQEPGPAKVAVTSS SSSSSSSSSIPSAEKVPTTKSTLWQEEMRTKDQPDGSSLSPAQSPSQSQPPAASSLREPGLESKEEESAMSSDRMDCGRKVRVESGYFSL EKTKQDLKAEEQQLPPPLSPPSPSTPNHRRSQVIEKFEALDIEKAEHMETNAVGPSPSSDTRQGRSEKRAFPRKRDFTNEAPPAPLPDAS ASPLSPHRRAKSLDRRSTEPSVTPDLLNFKKGWLTKQYEDGQWKKHWFVLADQSLRYYRDSVAEEAADLDGEIDLSACYDVTEYPVQRNY GFQIHTKEGEFTLSAMTSGIRRNWIQTIMKHVHPTTAPDVTSSLPEEKNKSSCSFETCPRPTEKQEAELGEPDPEQKRSRARERRREGRS KTFDWAEFRPIQQALAQERVGGVGPADTHEPLRPEAEPGELERERARRREERRKRFGMLDATDGPGTEDAALRMEVDRSPGLPMSDLKTH NVHVEIEQRWHQVETTPLREEKQVPIAPVHLSSEDGGDRLSTHELTSLLEKELEQSQKEASDLLEQNRLLQDQLRVALGREQSAREGYVL QATCERGFAAMEETHQKKIEDLQRQHQRELEKLREEKDRLLAEETAATISAIEAMKNAHREEMERELEKSQRSQISSVNSDVEALRRQYL EELQSVQRELEVLSEQYSQKCLENAHLAQALEAERQALRQCQRENQELNAHNQELNNRLAAEITRLRTLLTGDGGGEATGSPLAQGKDAY ELEVLLRVKESEIQYLKQEISSLKDELQTALRDKKYASDKYKDIYTELSIAKAKADCDISRLKEQLKAATEALGEKSPDSATVSGYDIMK SKSNPDFLKKDRSCVTRQLRNIRSKDAIRSHSESASPSALSSSPNNLSPTGWSQPKTPVPAQRERAPVSGTQEKNKIRPRGQRDSSYYWE IEASEVMLSTRIGSGSFGTVYKGKWHGDVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYMTKDNLAIVTQWCEGSSLYKHL HVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNN PFSFQSDVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCVKKVKEERPLFPQILSSIELLQHSL -------------------------------------------------------------- >In-frame_ENST00000395804_ENST00000534997_TCGA-D9-A4Z6-06A_MPRIP_chr17_17083402_+_RAF1_chr3_12641914_length(transcript)=4461nt_BP=3101nt GCCAGGCCGGCCAGGCCTGCGCCGCCGCCGCCGCCGCCGTCGCCGCCGCGCCGACCATGTCGGCAGCCAAGGAGAACCCGTGCAGGAAAT TCCAGGCCAACATCTTCAACAAGAGCAAGTGTCAGAACTGCTTCAAGCCCCGCGAGTCGCATCTGCTCAACGACGAGGACCTGACGCAGG CAAAACCCATTTATGGCGGTTGGCTGCTCCTGGCTCCAGATGGGACCGACTTTGACAACCCAGTGCACCGGTCTCGGAAATGGCAGCGAC GGTTCTTCATCCTTTACGAGCACGGCCTCTTGCGCTACGCCCTGGATGAGATGCCCACGACCCTTCCTCAGGGCACCATCAACATGAACC AGTGCACAGATGTGGTGGATGGGGAGGGCCGCACGGGCCAGAAGTTCTCCCTGTGTATTCTGACGCCTGAGAAGGAGCATTTCATCCGGG CGGAGACCAAGGAGATCGTCAGTGGGTGGCTGGAGATGCTCATGGTCTATCCCCGGACCAACAAGCAGAATCAGAAGAAGAAACGGAAAG TGGAGCCCCCCACACCACAGGAGCCTGGGCCTGCCAAGGTGGCTGTTACCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCATCCCCA GTGCTGAGAAAGTCCCCACCACCAAGTCCACACTCTGGCAGGAAGAAATGAGGACCAAGGACCAGCCAGATGGCAGCAGCCTGAGTCCAG CTCAGAGTCCCAGCCAGAGCCAGCCTCCTGCTGCCAGCTCCCTGCGGGAACCTGGGCTAGAGAGCAAAGAAGAGGAGAGCGCCATGAGTA GCGACCGCATGGACTGTGGCCGCAAAGTCCGGGTGGAGAGCGGCTACTTCTCTCTGGAGAAGACCAAACAGGACTTGAAGGCTGAAGAAC AGCAGCTGCCCCCGCCGCTCTCCCCTCCCAGCCCCAGCACCCCCAACCACAGGAGGTCCCAGGTGATTGAAAAGTTTGAGGCCTTGGACA TTGAGAAGGCAGAGCACATGGAGACCAATGCAGTGGGGCCCTCACCATCCAGCGACACACGCCAGGGCCGCAGCGAGAAGAGGGCGTTCC CTAGGAAGCGGGACTTCACCAATGAAGCCCCCCCAGCTCCTCTCCCAGACGCCTCGGCTTCCCCCCTGTCTCCACACCGAAGAGCCAAGT CACTGGACAGGAGGTCCACGGAGCCCTCCGTGACGCCCGACCTGCTGAATTTCAAGAAAGGCTGGCTGACTAAGCAGTATGAGGACGGCC AGTGGAAGAAACACTGGTTTGTCCTCGCCGATCAAAGCCTGAGATACTACAGGGATTCAGTGGCTGAGGAGGCAGCCGACTTGGATGGAG AAATTGACTTGTCCGCATGTTACGATGTCACAGAGTATCCAGTTCAGAGAAACTATGGCTTCCAGATACATACAAAGGAGGGCGAGTTTA CCCTGTCGGCCATGACATCTGGGATTCGGCGGAACTGGATCCAGACCATCATGAAGCACGTGCACCCGACCACTGCCCCGGATGTGACCA GCTCGTTGCCAGAGGAAAAAAACAAGAGCAGCTGCTCTTTTGAGACCTGCCCGAGGCCTACTGAGAAGCAAGAGGCAGAGCTGGGGGAGC CGGACCCTGAGCAGAAGAGGAGCCGCGCACGGGAGCGGAGGCGAGAGGGCCGCTCCAAGACCTTTGACTGGGCTGAGTTCCGTCCCATCC AGCAGGCCCTGGCTCAGGAGCGGGTGGGCGGCGTGGGGCCTGCTGACACCCACGAGCCCCTGCGCCCTGAGGCGGAGCCTGGGGAGCTGG AGCGGGAGCGTGCACGGAGGCGGGAGGAGCGCCGCAAGCGCTTCGGGATGCTCGACGCCACAGACGGGCCAGGCACTGAGGATGCAGCCC TGCGCATGGAGGTGGACCGGAGCCCAGGGCTGCCTATGAGCGACCTCAAAACGCATAACGTCCACGTGGAGATTGAGCAGCGGTGGCATC AGGTGGAGACCACACCTCTCCGGGAAGAGAAGCAGGTGCCCATCGCCCCCGTCCACCTGTCTTCTGAAGATGGGGGTGACCGGCTCTCCA CACACGAGCTGACCTCTCTGCTCGAGAAGGAGCTGGAGCAGAGCCAGAAGGAGGCCTCAGACCTTCTGGAGCAGAACCGGCTCCTGCAGG ACCAGCTGAGGGTGGCCCTGGGCCGGGAGCAGAGCGCCCGTGAGGGCTACGTGCTGCAGGCCACGTGCGAGCGAGGGTTTGCAGCAATGG AAGAAACGCACCAGAAGAAGATTGAAGATCTCCAGAGGCAGCACCAGCGGGAGCTAGAGAAACTTCGAGAAGAGAAAGACCGCCTCCTAG CCGAGGAGACAGCGGCCACCATCTCAGCCATCGAAGCCATGAAGAACGCCCACCGGGAGGAAATGGAGCGGGAGCTGGAGAAGAGCCAGC GGTCCCAGATCAGCAGCGTCAACTCGGATGTTGAGGCCCTGCGGCGCCAGTACCTGGAGGAGCTGCAGTCGGTGCAGCGGGAACTGGAGG TCCTCTCGGAGCAGTACTCGCAGAAGTGCCTGGAGAATGCCCATCTGGCCCAGGCGCTGGAGGCCGAGCGGCAGGCCCTGCGGCAGTGCC AGCGTGAGAACCAGGAGCTCAATGCCCACAACCAGGAGCTGAACAACCGCCTGGCTGCAGAGATCACACGGTTGCGGACGCTGCTGACTG GGGACGGCGGTGGGGAGGCCACTGGGTCACCCCTTGCACAGGGCAAGGATGCCTATGAACTAGAGGTCTTATTGCGGGTAAAGGAATCGG AAATACAGTACCTGAAACAGGAGATTAGCTCCCTCAAGGATGAGCTGCAGACGGCACTGCGGGACAAGAAGTACGCAAGTGACAAGTACA AAGACATCTACACAGAGCTCAGCATCGCGAAGGCTAAGGCTGACTGTGACATCAGCAGGTTGAAGGAGCAGCTCAAGGCTGCAACGGAAG CACTGGGGGAGAAGTCCCCTGACAGTGCCACGGTGTCCGGATATGATATAATGAAATCTAAAAGCAACCCTGACTTCTTGAAGAAAGACA GATCCTGTGTCACCCGGCAACTCAGAAACATCAGGTCCAAGGATGCAATTCGAAGTCACAGCGAATCAGCCTCACCTTCAGCCCTGTCCA GTAGCCCCAACAATCTGAGCCCAACAGGCTGGTCACAGCCGAAAACCCCCGTGCCAGCACAAAGAGAGCGGGCACCAGTATCTGGGACCC AGGAGAAAAACAAAATTAGGCCTCGTGGACAGAGAGATTCAAGCTATTATTGGGAAATAGAAGCCAGTGAAGTGATGCTGTCCACTCGGA TTGGGTCAGGCTCTTTTGGAACTGTTTATAAGGGTAAATGGCACGGAGATGTTGCAGTAAAGATCCTAAAGGTTGTCGACCCAACCCCAG AGCAATTCCAGGCCTTCAGGAATGAGGTGGCTGTTCTGCGCAAAACACGGCATGTGAACATTCTGCTTTTCATGGGGTACATGACAAAGG ACAACCTGGCAATTGTGACCCAGTGGTGCGAGGGCAGCAGCCTCTACAAACACCTGCATGTCCAGGAGACCAAGTTTCAGATGTTCCAGC TAATTGACATTGCCCGGCAGACGGCTCAGGGAATGGACTATTTGCATGCAAAGAACATCATCCATAGAGACATGAAATCCAACAATATAT TTCTCCATGAAGGCTTAACAGTGAAAATTGGAGATTTTGGTTTGGCAACAGTAAAGTCACGCTGGAGTGGTTCTCAGCAGGTTGAACAAC CTACTGGCTCTGTCCTCTGGATGGCCCCAGAGGTGATCCGAATGCAGGATAACAACCCATTCAGTTTCCAGTCGGATGTCTACTCCTATG GCATCGTATTGTATGAACTGATGACGGGGGAGCTTCCTTATTCTCACATCAACAACCGAGATCAGATCATCTTCATGGTGGGCCGAGGAT ATGCCTCCCCAGATCTTAGTAAGCTATATAAGAACTGCCCCAAAGCAATGAAGAGGCTGGTAGCTGACTGTGTGAAGAAAGTAAAGGAAG AGAGGCCTCTTTTTCCCCAGATCCTGTCTTCCATTGAGCTGCTCCAACACTCTCTACCGAAGATCAACCGGAGCGCTTCCGAGCCATCCT TGCATCGGGCAGCCCACACTGAGGATATCAATGCTTGCACGCTGACCACGTCCCCGAGGCTGCCTGTCTTCTAGTTGACTTTGCACCTGT CTTCAGGCTGCCAGGGGAGGAGGAGAAGCCAGCAGGCACCACTTTTCTGCTCCCTTTCTCCAGAGGCAGAACACATGTTTTCAGAGAAGC TGCTGCTAAGGACCTTCTAGACTGCTCACAGGGCCTTAACTTCATGTTGCCTTCTTTTCTATCCCTTTGGGCCCTGGGAGAAGGAAGCCA >In-frame_ENST00000395804_ENST00000534997_TCGA-D9-A4Z6-06A_MPRIP_chr17_17083402_+_RAF1_chr3_12641914_length(amino acids)=1385AA_start in transcript=56_stop in transcript=4213 MSAAKENPCRKFQANIFNKSKCQNCFKPRESHLLNDEDLTQAKPIYGGWLLLAPDGTDFDNPVHRSRKWQRRFFILYEHGLLRYALDEMP TTLPQGTINMNQCTDVVDGEGRTGQKFSLCILTPEKEHFIRAETKEIVSGWLEMLMVYPRTNKQNQKKKRKVEPPTPQEPGPAKVAVTSS SSSSSSSSSIPSAEKVPTTKSTLWQEEMRTKDQPDGSSLSPAQSPSQSQPPAASSLREPGLESKEEESAMSSDRMDCGRKVRVESGYFSL EKTKQDLKAEEQQLPPPLSPPSPSTPNHRRSQVIEKFEALDIEKAEHMETNAVGPSPSSDTRQGRSEKRAFPRKRDFTNEAPPAPLPDAS ASPLSPHRRAKSLDRRSTEPSVTPDLLNFKKGWLTKQYEDGQWKKHWFVLADQSLRYYRDSVAEEAADLDGEIDLSACYDVTEYPVQRNY GFQIHTKEGEFTLSAMTSGIRRNWIQTIMKHVHPTTAPDVTSSLPEEKNKSSCSFETCPRPTEKQEAELGEPDPEQKRSRARERRREGRS KTFDWAEFRPIQQALAQERVGGVGPADTHEPLRPEAEPGELERERARRREERRKRFGMLDATDGPGTEDAALRMEVDRSPGLPMSDLKTH NVHVEIEQRWHQVETTPLREEKQVPIAPVHLSSEDGGDRLSTHELTSLLEKELEQSQKEASDLLEQNRLLQDQLRVALGREQSAREGYVL QATCERGFAAMEETHQKKIEDLQRQHQRELEKLREEKDRLLAEETAATISAIEAMKNAHREEMERELEKSQRSQISSVNSDVEALRRQYL EELQSVQRELEVLSEQYSQKCLENAHLAQALEAERQALRQCQRENQELNAHNQELNNRLAAEITRLRTLLTGDGGGEATGSPLAQGKDAY ELEVLLRVKESEIQYLKQEISSLKDELQTALRDKKYASDKYKDIYTELSIAKAKADCDISRLKEQLKAATEALGEKSPDSATVSGYDIMK SKSNPDFLKKDRSCVTRQLRNIRSKDAIRSHSESASPSALSSSPNNLSPTGWSQPKTPVPAQRERAPVSGTQEKNKIRPRGQRDSSYYWE IEASEVMLSTRIGSGSFGTVYKGKWHGDVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYMTKDNLAIVTQWCEGSSLYKHL HVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNN PFSFQSDVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCVKKVKEERPLFPQILSSIELLQHSL -------------------------------------------------------------- >In-frame_ENST00000395804_ENST00000542177_TCGA-D9-A4Z6-06A_MPRIP_chr17_17083402_+_RAF1_chr3_12641914_length(transcript)=4395nt_BP=3101nt GCCAGGCCGGCCAGGCCTGCGCCGCCGCCGCCGCCGCCGTCGCCGCCGCGCCGACCATGTCGGCAGCCAAGGAGAACCCGTGCAGGAAAT TCCAGGCCAACATCTTCAACAAGAGCAAGTGTCAGAACTGCTTCAAGCCCCGCGAGTCGCATCTGCTCAACGACGAGGACCTGACGCAGG CAAAACCCATTTATGGCGGTTGGCTGCTCCTGGCTCCAGATGGGACCGACTTTGACAACCCAGTGCACCGGTCTCGGAAATGGCAGCGAC GGTTCTTCATCCTTTACGAGCACGGCCTCTTGCGCTACGCCCTGGATGAGATGCCCACGACCCTTCCTCAGGGCACCATCAACATGAACC AGTGCACAGATGTGGTGGATGGGGAGGGCCGCACGGGCCAGAAGTTCTCCCTGTGTATTCTGACGCCTGAGAAGGAGCATTTCATCCGGG CGGAGACCAAGGAGATCGTCAGTGGGTGGCTGGAGATGCTCATGGTCTATCCCCGGACCAACAAGCAGAATCAGAAGAAGAAACGGAAAG TGGAGCCCCCCACACCACAGGAGCCTGGGCCTGCCAAGGTGGCTGTTACCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCATCCCCA GTGCTGAGAAAGTCCCCACCACCAAGTCCACACTCTGGCAGGAAGAAATGAGGACCAAGGACCAGCCAGATGGCAGCAGCCTGAGTCCAG CTCAGAGTCCCAGCCAGAGCCAGCCTCCTGCTGCCAGCTCCCTGCGGGAACCTGGGCTAGAGAGCAAAGAAGAGGAGAGCGCCATGAGTA GCGACCGCATGGACTGTGGCCGCAAAGTCCGGGTGGAGAGCGGCTACTTCTCTCTGGAGAAGACCAAACAGGACTTGAAGGCTGAAGAAC AGCAGCTGCCCCCGCCGCTCTCCCCTCCCAGCCCCAGCACCCCCAACCACAGGAGGTCCCAGGTGATTGAAAAGTTTGAGGCCTTGGACA TTGAGAAGGCAGAGCACATGGAGACCAATGCAGTGGGGCCCTCACCATCCAGCGACACACGCCAGGGCCGCAGCGAGAAGAGGGCGTTCC CTAGGAAGCGGGACTTCACCAATGAAGCCCCCCCAGCTCCTCTCCCAGACGCCTCGGCTTCCCCCCTGTCTCCACACCGAAGAGCCAAGT CACTGGACAGGAGGTCCACGGAGCCCTCCGTGACGCCCGACCTGCTGAATTTCAAGAAAGGCTGGCTGACTAAGCAGTATGAGGACGGCC AGTGGAAGAAACACTGGTTTGTCCTCGCCGATCAAAGCCTGAGATACTACAGGGATTCAGTGGCTGAGGAGGCAGCCGACTTGGATGGAG AAATTGACTTGTCCGCATGTTACGATGTCACAGAGTATCCAGTTCAGAGAAACTATGGCTTCCAGATACATACAAAGGAGGGCGAGTTTA CCCTGTCGGCCATGACATCTGGGATTCGGCGGAACTGGATCCAGACCATCATGAAGCACGTGCACCCGACCACTGCCCCGGATGTGACCA GCTCGTTGCCAGAGGAAAAAAACAAGAGCAGCTGCTCTTTTGAGACCTGCCCGAGGCCTACTGAGAAGCAAGAGGCAGAGCTGGGGGAGC CGGACCCTGAGCAGAAGAGGAGCCGCGCACGGGAGCGGAGGCGAGAGGGCCGCTCCAAGACCTTTGACTGGGCTGAGTTCCGTCCCATCC AGCAGGCCCTGGCTCAGGAGCGGGTGGGCGGCGTGGGGCCTGCTGACACCCACGAGCCCCTGCGCCCTGAGGCGGAGCCTGGGGAGCTGG AGCGGGAGCGTGCACGGAGGCGGGAGGAGCGCCGCAAGCGCTTCGGGATGCTCGACGCCACAGACGGGCCAGGCACTGAGGATGCAGCCC TGCGCATGGAGGTGGACCGGAGCCCAGGGCTGCCTATGAGCGACCTCAAAACGCATAACGTCCACGTGGAGATTGAGCAGCGGTGGCATC AGGTGGAGACCACACCTCTCCGGGAAGAGAAGCAGGTGCCCATCGCCCCCGTCCACCTGTCTTCTGAAGATGGGGGTGACCGGCTCTCCA CACACGAGCTGACCTCTCTGCTCGAGAAGGAGCTGGAGCAGAGCCAGAAGGAGGCCTCAGACCTTCTGGAGCAGAACCGGCTCCTGCAGG ACCAGCTGAGGGTGGCCCTGGGCCGGGAGCAGAGCGCCCGTGAGGGCTACGTGCTGCAGGCCACGTGCGAGCGAGGGTTTGCAGCAATGG AAGAAACGCACCAGAAGAAGATTGAAGATCTCCAGAGGCAGCACCAGCGGGAGCTAGAGAAACTTCGAGAAGAGAAAGACCGCCTCCTAG CCGAGGAGACAGCGGCCACCATCTCAGCCATCGAAGCCATGAAGAACGCCCACCGGGAGGAAATGGAGCGGGAGCTGGAGAAGAGCCAGC GGTCCCAGATCAGCAGCGTCAACTCGGATGTTGAGGCCCTGCGGCGCCAGTACCTGGAGGAGCTGCAGTCGGTGCAGCGGGAACTGGAGG TCCTCTCGGAGCAGTACTCGCAGAAGTGCCTGGAGAATGCCCATCTGGCCCAGGCGCTGGAGGCCGAGCGGCAGGCCCTGCGGCAGTGCC AGCGTGAGAACCAGGAGCTCAATGCCCACAACCAGGAGCTGAACAACCGCCTGGCTGCAGAGATCACACGGTTGCGGACGCTGCTGACTG GGGACGGCGGTGGGGAGGCCACTGGGTCACCCCTTGCACAGGGCAAGGATGCCTATGAACTAGAGGTCTTATTGCGGGTAAAGGAATCGG AAATACAGTACCTGAAACAGGAGATTAGCTCCCTCAAGGATGAGCTGCAGACGGCACTGCGGGACAAGAAGTACGCAAGTGACAAGTACA AAGACATCTACACAGAGCTCAGCATCGCGAAGGCTAAGGCTGACTGTGACATCAGCAGGTTGAAGGAGCAGCTCAAGGCTGCAACGGAAG CACTGGGGGAGAAGTCCCCTGACAGTGCCACGGTGTCCGGATATGATATAATGAAATCTAAAAGCAACCCTGACTTCTTGAAGAAAGACA GATCCTGTGTCACCCGGCAACTCAGAAACATCAGGTCCAAGGATGCAATTCGAAGTCACAGCGAATCAGCCTCACCTTCAGCCCTGTCCA GTAGCCCCAACAATCTGAGCCCAACAGGCTGGTCACAGCCGAAAACCCCCGTGCCAGCACAAAGAGAGCGGGCACCAGTATCTGGGACCC AGGAGAAAAACAAAATTAGGCCTCGTGGACAGAGAGATTCAAGCTATTATTGGGAAATAGAAGCCAGTGAAGTGATGCTGTCCACTCGGA TTGGGTCAGGCTCTTTTGGAACTGTTTATAAGGGTAAATGGCACGGAGATGTTGCAGTAAAGATCCTAAAGGTTGTCGACCCAACCCCAG AGCAATTCCAGGCCTTCAGGAATGAGGTGGCTGTTCTGCGCAAAACACGGCATGTGAACATTCTGCTTTTCATGGGGTACATGACAAAGG ACAACCTGGCAATTGTGACCCAGTGGTGCGAGGGCAGCAGCCTCTACAAACACCTGCATGTCCAGGAGACCAAGTTTCAGATGTTCCAGC TAATTGACATTGCCCGGCAGACGGCTCAGGGAATGGACTATTTGCATGCAAAGAACATCATCCATAGAGACATGAAATCCAACAATATAT TTCTCCATGAAGGCTTAACAGTGAAAATTGGAGATTTTGGTTTGGCAACAGTAAAGTCACGCTGGAGTGGTTCTCAGCAGGTTGAACAAC CTACTGGCTCTGTCCTCTGGATGGCCCCAGAGGTGATCCGAATGCAGGATAACAACCCATTCAGTTTCCAGTCGGATGTCTACTCCTATG GCATCGTATTGTATGAACTGATGACGGGGGAGCTTCCTTATTCTCACATCAACAACCGAGATCAGATCATCTTCATGGTGGGCCGAGGAT ATGCCTCCCCAGATCTTAGTAAGCTATATAAGAACTGCCCCAAAGCAATGAAGAGGCTGGTAGCTGACTGTGTGAAGAAAGTAAAGGAAG AGAGGCCTCTTTTTCCCCAGATCCTGTCTTCCATTGAGCTGCTCCAACACTCTCTACCGAAGATCAACCGGAGCGCTTCCGAGCCATCCT TGCATCGGGCAGCCCACACTGAGGATATCAATGCTTGCACGCTGACCACGTCCCCGAGGCTGCCTGTCTTCTAGTTGACTTTGCACCTGT CTTCAGGCTGCCAGGGGAGGAGGAGAAGCCAGCAGGCACCACTTTTCTGCTCCCTTTCTCCAGAGGCAGAACACATGTTTTCAGAGAAGC >In-frame_ENST00000395804_ENST00000542177_TCGA-D9-A4Z6-06A_MPRIP_chr17_17083402_+_RAF1_chr3_12641914_length(amino acids)=1385AA_start in transcript=56_stop in transcript=4213 MSAAKENPCRKFQANIFNKSKCQNCFKPRESHLLNDEDLTQAKPIYGGWLLLAPDGTDFDNPVHRSRKWQRRFFILYEHGLLRYALDEMP TTLPQGTINMNQCTDVVDGEGRTGQKFSLCILTPEKEHFIRAETKEIVSGWLEMLMVYPRTNKQNQKKKRKVEPPTPQEPGPAKVAVTSS SSSSSSSSSIPSAEKVPTTKSTLWQEEMRTKDQPDGSSLSPAQSPSQSQPPAASSLREPGLESKEEESAMSSDRMDCGRKVRVESGYFSL EKTKQDLKAEEQQLPPPLSPPSPSTPNHRRSQVIEKFEALDIEKAEHMETNAVGPSPSSDTRQGRSEKRAFPRKRDFTNEAPPAPLPDAS ASPLSPHRRAKSLDRRSTEPSVTPDLLNFKKGWLTKQYEDGQWKKHWFVLADQSLRYYRDSVAEEAADLDGEIDLSACYDVTEYPVQRNY GFQIHTKEGEFTLSAMTSGIRRNWIQTIMKHVHPTTAPDVTSSLPEEKNKSSCSFETCPRPTEKQEAELGEPDPEQKRSRARERRREGRS KTFDWAEFRPIQQALAQERVGGVGPADTHEPLRPEAEPGELERERARRREERRKRFGMLDATDGPGTEDAALRMEVDRSPGLPMSDLKTH NVHVEIEQRWHQVETTPLREEKQVPIAPVHLSSEDGGDRLSTHELTSLLEKELEQSQKEASDLLEQNRLLQDQLRVALGREQSAREGYVL QATCERGFAAMEETHQKKIEDLQRQHQRELEKLREEKDRLLAEETAATISAIEAMKNAHREEMERELEKSQRSQISSVNSDVEALRRQYL EELQSVQRELEVLSEQYSQKCLENAHLAQALEAERQALRQCQRENQELNAHNQELNNRLAAEITRLRTLLTGDGGGEATGSPLAQGKDAY ELEVLLRVKESEIQYLKQEISSLKDELQTALRDKKYASDKYKDIYTELSIAKAKADCDISRLKEQLKAATEALGEKSPDSATVSGYDIMK SKSNPDFLKKDRSCVTRQLRNIRSKDAIRSHSESASPSALSSSPNNLSPTGWSQPKTPVPAQRERAPVSGTQEKNKIRPRGQRDSSYYWE IEASEVMLSTRIGSGSFGTVYKGKWHGDVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYMTKDNLAIVTQWCEGSSLYKHL HVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNN PFSFQSDVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCVKKVKEERPLFPQILSSIELLQHSL -------------------------------------------------------------- >In-frame_ENST00000341712_ENST00000251849_TCGA-D9-A4Z6-06A_MPRIP_chr17_17083402_+_RAF1_chr3_12641914_length(transcript)=5071nt_BP=3045nt ATGTCGGCAGCCAAGGAGAACCCGTGCAGGAAATTCCAGGCCAACATCTTCAACAAGAGCAAGTGTCAGAACTGCTTCAAGCCCCGCGAG TCGCATCTGCTCAACGACGAGGACCTGACGCAGGCAAAACCCATTTATGGCGGTTGGCTGCTCCTGGCTCCAGATGGGACCGACTTTGAC AACCCAGTGCACCGGTCTCGGAAATGGCAGCGACGGTTCTTCATCCTTTACGAGCACGGCCTCTTGCGCTACGCCCTGGATGAGATGCCC ACGACCCTTCCTCAGGGCACCATCAACATGAACCAGTGCACAGATGTGGTGGATGGGGAGGGCCGCACGGGCCAGAAGTTCTCCCTGTGT ATTCTGACGCCTGAGAAGGAGCATTTCATCCGGGCGGAGACCAAGGAGATCGTCAGTGGGTGGCTGGAGATGCTCATGGTCTATCCCCGG ACCAACAAGCAGAATCAGAAGAAGAAACGGAAAGTGGAGCCCCCCACACCACAGGAGCCTGGGCCTGCCAAGGTGGCTGTTACCAGCAGC AGCAGCAGCAGCAGCAGCAGCAGCAGCATCCCCAGTGCTGAGAAAGTCCCCACCACCAAGTCCACACTCTGGCAGGAAGAAATGAGGACC AAGGACCAGCCAGATGGCAGCAGCCTGAGTCCAGCTCAGAGTCCCAGCCAGAGCCAGCCTCCTGCTGCCAGCTCCCTGCGGGAACCTGGG CTAGAGAGCAAAGAAGAGGAGAGCGCCATGAGTAGCGACCGCATGGACTGTGGCCGCAAAGTCCGGGTGGAGAGCGGCTACTTCTCTCTG GAGAAGACCAAACAGGACTTGAAGGCTGAAGAACAGCAGCTGCCCCCGCCGCTCTCCCCTCCCAGCCCCAGCACCCCCAACCACAGGAGG TCCCAGGTGATTGAAAAGTTTGAGGCCTTGGACATTGAGAAGGCAGAGCACATGGAGACCAATGCAGTGGGGCCCTCACCATCCAGCGAC ACACGCCAGGGCCGCAGCGAGAAGAGGGCGTTCCCTAGGAAGCGGGACTTCACCAATGAAGCCCCCCCAGCTCCTCTCCCAGACGCCTCG GCTTCCCCCCTGTCTCCACACCGAAGAGCCAAGTCACTGGACAGGAGGTCCACGGAGCCCTCCGTGACGCCCGACCTGCTGAATTTCAAG AAAGGCTGGCTGACTAAGCAGTATGAGGACGGCCAGTGGAAGAAACACTGGTTTGTCCTCGCCGATCAAAGCCTGAGATACTACAGGGAT TCAGTGGCTGAGGAGGCAGCCGACTTGGATGGAGAAATTGACTTGTCCGCATGTTACGATGTCACAGAGTATCCAGTTCAGAGAAACTAT GGCTTCCAGATACATACAAAGGAGGGCGAGTTTACCCTGTCGGCCATGACATCTGGGATTCGGCGGAACTGGATCCAGACCATCATGAAG CACGTGCACCCGACCACTGCCCCGGATGTGACCAGCTCGTTGCCAGAGGAAAAAAACAAGAGCAGCTGCTCTTTTGAGACCTGCCCGAGG CCTACTGAGAAGCAAGAGGCAGAGCTGGGGGAGCCGGACCCTGAGCAGAAGAGGAGCCGCGCACGGGAGCGGAGGCGAGAGGGCCGCTCC AAGACCTTTGACTGGGCTGAGTTCCGTCCCATCCAGCAGGCCCTGGCTCAGGAGCGGGTGGGCGGCGTGGGGCCTGCTGACACCCACGAG CCCCTGCGCCCTGAGGCGGAGCCTGGGGAGCTGGAGCGGGAGCGTGCACGGAGGCGGGAGGAGCGCCGCAAGCGCTTCGGGATGCTCGAC GCCACAGACGGGCCAGGCACTGAGGATGCAGCCCTGCGCATGGAGGTGGACCGGAGCCCAGGGCTGCCTATGAGCGACCTCAAAACGCAT AACGTCCACGTGGAGATTGAGCAGCGGTGGCATCAGGTGGAGACCACACCTCTCCGGGAAGAGAAGCAGGTGCCCATCGCCCCCGTCCAC CTGTCTTCTGAAGATGGGGGTGACCGGCTCTCCACACACGAGCTGACCTCTCTGCTCGAGAAGGAGCTGGAGCAGAGCCAGAAGGAGGCC TCAGACCTTCTGGAGCAGAACCGGCTCCTGCAGGACCAGCTGAGGGTGGCCCTGGGCCGGGAGCAGAGCGCCCGTGAGGGCTACGTGCTG CAGGCCACGTGCGAGCGAGGGTTTGCAGCAATGGAAGAAACGCACCAGAAGAAGATTGAAGATCTCCAGAGGCAGCACCAGCGGGAGCTA GAGAAACTTCGAGAAGAGAAAGACCGCCTCCTAGCCGAGGAGACAGCGGCCACCATCTCAGCCATCGAAGCCATGAAGAACGCCCACCGG GAGGAAATGGAGCGGGAGCTGGAGAAGAGCCAGCGGTCCCAGATCAGCAGCGTCAACTCGGATGTTGAGGCCCTGCGGCGCCAGTACCTG GAGGAGCTGCAGTCGGTGCAGCGGGAACTGGAGGTCCTCTCGGAGCAGTACTCGCAGAAGTGCCTGGAGAATGCCCATCTGGCCCAGGCG CTGGAGGCCGAGCGGCAGGCCCTGCGGCAGTGCCAGCGTGAGAACCAGGAGCTCAATGCCCACAACCAGGAGCTGAACAACCGCCTGGCT GCAGAGATCACACGGTTGCGGACGCTGCTGACTGGGGACGGCGGTGGGGAGGCCACTGGGTCACCCCTTGCACAGGGCAAGGATGCCTAT GAACTAGAGGTCTTATTGCGGGTAAAGGAATCGGAAATACAGTACCTGAAACAGGAGATTAGCTCCCTCAAGGATGAGCTGCAGACGGCA CTGCGGGACAAGAAGTACGCAAGTGACAAGTACAAAGACATCTACACAGAGCTCAGCATCGCGAAGGCTAAGGCTGACTGTGACATCAGC AGGTTGAAGGAGCAGCTCAAGGCTGCAACGGAAGCACTGGGGGAGAAGTCCCCTGACAGTGCCACGGTGTCCGGATATGATATAATGAAA TCTAAAAGCAACCCTGACTTCTTGAAGAAAGACAGATCCTGTGTCACCCGGCAACTCAGAAACATCAGGTCCAAGGATGCAATTCGAAGT CACAGCGAATCAGCCTCACCTTCAGCCCTGTCCAGTAGCCCCAACAATCTGAGCCCAACAGGCTGGTCACAGCCGAAAACCCCCGTGCCA GCACAAAGAGAGCGGGCACCAGTATCTGGGACCCAGGAGAAAAACAAAATTAGGCCTCGTGGACAGAGAGATTCAAGCTATTATTGGGAA ATAGAAGCCAGTGAAGTGATGCTGTCCACTCGGATTGGGTCAGGCTCTTTTGGAACTGTTTATAAGGGTAAATGGCACGGAGATGTTGCA GTAAAGATCCTAAAGGTTGTCGACCCAACCCCAGAGCAATTCCAGGCCTTCAGGAATGAGGTGGCTGTTCTGCGCAAAACACGGCATGTG AACATTCTGCTTTTCATGGGGTACATGACAAAGGACAACCTGGCAATTGTGACCCAGTGGTGCGAGGGCAGCAGCCTCTACAAACACCTG CATGTCCAGGAGACCAAGTTTCAGATGTTCCAGCTAATTGACATTGCCCGGCAGACGGCTCAGGGAATGGACTATTTGCATGCAAAGAAC ATCATCCATAGAGACATGAAATCCAACAATATATTTCTCCATGAAGGCTTAACAGTGAAAATTGGAGATTTTGGTTTGGCAACAGTAAAG TCACGCTGGAGTGGTTCTCAGCAGGTTGAACAACCTACTGGCTCTGTCCTCTGGATGGCCCCAGAGGTGATCCGAATGCAGGATAACAAC CCATTCAGTTTCCAGTCGGATGTCTACTCCTATGGCATCGTATTGTATGAACTGATGACGGGGGAGCTTCCTTATTCTCACATCAACAAC CGAGATCAGATCATCTTCATGGTGGGCCGAGGATATGCCTCCCCAGATCTTAGTAAGCTATATAAGAACTGCCCCAAAGCAATGAAGAGG CTGGTAGCTGACTGTGTGAAGAAAGTAAAGGAAGAGAGGCCTCTTTTTCCCCAGATCCTGTCTTCCATTGAGCTGCTCCAACACTCTCTA CCGAAGATCAACCGGAGCGCTTCCGAGCCATCCTTGCATCGGGCAGCCCACACTGAGGATATCAATGCTTGCACGCTGACCACGTCCCCG AGGCTGCCTGTCTTCTAGTTGACTTTGCACCTGTCTTCAGGCTGCCAGGGGAGGAGGAGAAGCCAGCAGGCACCACTTTTCTGCTCCCTT TCTCCAGAGGCAGAACACATGTTTTCAGAGAAGCTGCTGCTAAGGACCTTCTAGACTGCTCACAGGGCCTTAACTTCATGTTGCCTTCTT TTCTATCCCTTTGGGCCCTGGGAGAAGGAAGCCATTTGCAGTGCTGGTGTGTCCTGCTCCCTCCCCACATTCCCCATGCTCAAGGCCCAG CCTTCTGTAGATGCGCAAGTGGATGTTGATGGTAGTACAAAAAGCAGGGGCCCAGCCCCAGCTGTTGGCTACATGAGTATTTAGAGGAAG TAAGGTAGCAGGCAGTCCAGCCCTGATGTGGAGACACATGGGATTTTGGAAATCAGCTTCTGGAGGAATGCATGTCACAGGCGGGACTTT CTTCAGAGAGTGGTGCAGCGCCAGACATTTTGCACATAAGGCACCAAACAGCCCAGGACTGCCGAGACTCTGGCCGCCCGAAGGAGCCTG CTTTGGTACTATGGAACTTTTCTTAGGGGACACGTCCTCCTTTCACAGCTTCTAAGGTGTCCAGTGCATTGGGATGGTTTTCCAGGCAAG GCACTCGGCCAATCCGCATCTCAGCCCTCTCAGGGAGCAGTCTTCCATCATGCTGAATTTTGTCTTCCAGGAGCTGCCCCTATGGGGCGG GGCCGCAGGGCCAGCCTTGTTTCTCTAACAAACAAACAAACAAACAGCCTTGTTTCTCTAGTCACATCATGTGTATACAAGGAAGCCAGG AATACAGGTTTTCTTGATGATTTGGGTTTTAATTTTGTTTTTATTGCACCTGACAAAATACAGTTATCTGATGGTCCCTCAATTATGTTA >In-frame_ENST00000341712_ENST00000251849_TCGA-D9-A4Z6-06A_MPRIP_chr17_17083402_+_RAF1_chr3_12641914_length(amino acids)=1385AA_start in transcript=0_stop in transcript=4157 MSAAKENPCRKFQANIFNKSKCQNCFKPRESHLLNDEDLTQAKPIYGGWLLLAPDGTDFDNPVHRSRKWQRRFFILYEHGLLRYALDEMP TTLPQGTINMNQCTDVVDGEGRTGQKFSLCILTPEKEHFIRAETKEIVSGWLEMLMVYPRTNKQNQKKKRKVEPPTPQEPGPAKVAVTSS SSSSSSSSSIPSAEKVPTTKSTLWQEEMRTKDQPDGSSLSPAQSPSQSQPPAASSLREPGLESKEEESAMSSDRMDCGRKVRVESGYFSL EKTKQDLKAEEQQLPPPLSPPSPSTPNHRRSQVIEKFEALDIEKAEHMETNAVGPSPSSDTRQGRSEKRAFPRKRDFTNEAPPAPLPDAS ASPLSPHRRAKSLDRRSTEPSVTPDLLNFKKGWLTKQYEDGQWKKHWFVLADQSLRYYRDSVAEEAADLDGEIDLSACYDVTEYPVQRNY GFQIHTKEGEFTLSAMTSGIRRNWIQTIMKHVHPTTAPDVTSSLPEEKNKSSCSFETCPRPTEKQEAELGEPDPEQKRSRARERRREGRS KTFDWAEFRPIQQALAQERVGGVGPADTHEPLRPEAEPGELERERARRREERRKRFGMLDATDGPGTEDAALRMEVDRSPGLPMSDLKTH NVHVEIEQRWHQVETTPLREEKQVPIAPVHLSSEDGGDRLSTHELTSLLEKELEQSQKEASDLLEQNRLLQDQLRVALGREQSAREGYVL QATCERGFAAMEETHQKKIEDLQRQHQRELEKLREEKDRLLAEETAATISAIEAMKNAHREEMERELEKSQRSQISSVNSDVEALRRQYL EELQSVQRELEVLSEQYSQKCLENAHLAQALEAERQALRQCQRENQELNAHNQELNNRLAAEITRLRTLLTGDGGGEATGSPLAQGKDAY ELEVLLRVKESEIQYLKQEISSLKDELQTALRDKKYASDKYKDIYTELSIAKAKADCDISRLKEQLKAATEALGEKSPDSATVSGYDIMK SKSNPDFLKKDRSCVTRQLRNIRSKDAIRSHSESASPSALSSSPNNLSPTGWSQPKTPVPAQRERAPVSGTQEKNKIRPRGQRDSSYYWE IEASEVMLSTRIGSGSFGTVYKGKWHGDVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYMTKDNLAIVTQWCEGSSLYKHL HVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNN PFSFQSDVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCVKKVKEERPLFPQILSSIELLQHSL -------------------------------------------------------------- >In-frame_ENST00000341712_ENST00000442415_TCGA-D9-A4Z6-06A_MPRIP_chr17_17083402_+_RAF1_chr3_12641914_length(transcript)=4874nt_BP=3045nt ATGTCGGCAGCCAAGGAGAACCCGTGCAGGAAATTCCAGGCCAACATCTTCAACAAGAGCAAGTGTCAGAACTGCTTCAAGCCCCGCGAG TCGCATCTGCTCAACGACGAGGACCTGACGCAGGCAAAACCCATTTATGGCGGTTGGCTGCTCCTGGCTCCAGATGGGACCGACTTTGAC AACCCAGTGCACCGGTCTCGGAAATGGCAGCGACGGTTCTTCATCCTTTACGAGCACGGCCTCTTGCGCTACGCCCTGGATGAGATGCCC ACGACCCTTCCTCAGGGCACCATCAACATGAACCAGTGCACAGATGTGGTGGATGGGGAGGGCCGCACGGGCCAGAAGTTCTCCCTGTGT ATTCTGACGCCTGAGAAGGAGCATTTCATCCGGGCGGAGACCAAGGAGATCGTCAGTGGGTGGCTGGAGATGCTCATGGTCTATCCCCGG ACCAACAAGCAGAATCAGAAGAAGAAACGGAAAGTGGAGCCCCCCACACCACAGGAGCCTGGGCCTGCCAAGGTGGCTGTTACCAGCAGC AGCAGCAGCAGCAGCAGCAGCAGCAGCATCCCCAGTGCTGAGAAAGTCCCCACCACCAAGTCCACACTCTGGCAGGAAGAAATGAGGACC AAGGACCAGCCAGATGGCAGCAGCCTGAGTCCAGCTCAGAGTCCCAGCCAGAGCCAGCCTCCTGCTGCCAGCTCCCTGCGGGAACCTGGG CTAGAGAGCAAAGAAGAGGAGAGCGCCATGAGTAGCGACCGCATGGACTGTGGCCGCAAAGTCCGGGTGGAGAGCGGCTACTTCTCTCTG GAGAAGACCAAACAGGACTTGAAGGCTGAAGAACAGCAGCTGCCCCCGCCGCTCTCCCCTCCCAGCCCCAGCACCCCCAACCACAGGAGG TCCCAGGTGATTGAAAAGTTTGAGGCCTTGGACATTGAGAAGGCAGAGCACATGGAGACCAATGCAGTGGGGCCCTCACCATCCAGCGAC ACACGCCAGGGCCGCAGCGAGAAGAGGGCGTTCCCTAGGAAGCGGGACTTCACCAATGAAGCCCCCCCAGCTCCTCTCCCAGACGCCTCG GCTTCCCCCCTGTCTCCACACCGAAGAGCCAAGTCACTGGACAGGAGGTCCACGGAGCCCTCCGTGACGCCCGACCTGCTGAATTTCAAG AAAGGCTGGCTGACTAAGCAGTATGAGGACGGCCAGTGGAAGAAACACTGGTTTGTCCTCGCCGATCAAAGCCTGAGATACTACAGGGAT TCAGTGGCTGAGGAGGCAGCCGACTTGGATGGAGAAATTGACTTGTCCGCATGTTACGATGTCACAGAGTATCCAGTTCAGAGAAACTAT GGCTTCCAGATACATACAAAGGAGGGCGAGTTTACCCTGTCGGCCATGACATCTGGGATTCGGCGGAACTGGATCCAGACCATCATGAAG CACGTGCACCCGACCACTGCCCCGGATGTGACCAGCTCGTTGCCAGAGGAAAAAAACAAGAGCAGCTGCTCTTTTGAGACCTGCCCGAGG CCTACTGAGAAGCAAGAGGCAGAGCTGGGGGAGCCGGACCCTGAGCAGAAGAGGAGCCGCGCACGGGAGCGGAGGCGAGAGGGCCGCTCC AAGACCTTTGACTGGGCTGAGTTCCGTCCCATCCAGCAGGCCCTGGCTCAGGAGCGGGTGGGCGGCGTGGGGCCTGCTGACACCCACGAG CCCCTGCGCCCTGAGGCGGAGCCTGGGGAGCTGGAGCGGGAGCGTGCACGGAGGCGGGAGGAGCGCCGCAAGCGCTTCGGGATGCTCGAC GCCACAGACGGGCCAGGCACTGAGGATGCAGCCCTGCGCATGGAGGTGGACCGGAGCCCAGGGCTGCCTATGAGCGACCTCAAAACGCAT AACGTCCACGTGGAGATTGAGCAGCGGTGGCATCAGGTGGAGACCACACCTCTCCGGGAAGAGAAGCAGGTGCCCATCGCCCCCGTCCAC CTGTCTTCTGAAGATGGGGGTGACCGGCTCTCCACACACGAGCTGACCTCTCTGCTCGAGAAGGAGCTGGAGCAGAGCCAGAAGGAGGCC TCAGACCTTCTGGAGCAGAACCGGCTCCTGCAGGACCAGCTGAGGGTGGCCCTGGGCCGGGAGCAGAGCGCCCGTGAGGGCTACGTGCTG CAGGCCACGTGCGAGCGAGGGTTTGCAGCAATGGAAGAAACGCACCAGAAGAAGATTGAAGATCTCCAGAGGCAGCACCAGCGGGAGCTA GAGAAACTTCGAGAAGAGAAAGACCGCCTCCTAGCCGAGGAGACAGCGGCCACCATCTCAGCCATCGAAGCCATGAAGAACGCCCACCGG GAGGAAATGGAGCGGGAGCTGGAGAAGAGCCAGCGGTCCCAGATCAGCAGCGTCAACTCGGATGTTGAGGCCCTGCGGCGCCAGTACCTG GAGGAGCTGCAGTCGGTGCAGCGGGAACTGGAGGTCCTCTCGGAGCAGTACTCGCAGAAGTGCCTGGAGAATGCCCATCTGGCCCAGGCG CTGGAGGCCGAGCGGCAGGCCCTGCGGCAGTGCCAGCGTGAGAACCAGGAGCTCAATGCCCACAACCAGGAGCTGAACAACCGCCTGGCT GCAGAGATCACACGGTTGCGGACGCTGCTGACTGGGGACGGCGGTGGGGAGGCCACTGGGTCACCCCTTGCACAGGGCAAGGATGCCTAT GAACTAGAGGTCTTATTGCGGGTAAAGGAATCGGAAATACAGTACCTGAAACAGGAGATTAGCTCCCTCAAGGATGAGCTGCAGACGGCA CTGCGGGACAAGAAGTACGCAAGTGACAAGTACAAAGACATCTACACAGAGCTCAGCATCGCGAAGGCTAAGGCTGACTGTGACATCAGC AGGTTGAAGGAGCAGCTCAAGGCTGCAACGGAAGCACTGGGGGAGAAGTCCCCTGACAGTGCCACGGTGTCCGGATATGATATAATGAAA TCTAAAAGCAACCCTGACTTCTTGAAGAAAGACAGATCCTGTGTCACCCGGCAACTCAGAAACATCAGGTCCAAGGATGCAATTCGAAGT CACAGCGAATCAGCCTCACCTTCAGCCCTGTCCAGTAGCCCCAACAATCTGAGCCCAACAGGCTGGTCACAGCCGAAAACCCCCGTGCCA GCACAAAGAGAGCGGGCACCAGTATCTGGGACCCAGGAGAAAAACAAAATTAGGCCTCGTGGACAGAGAGATTCAAGCTATTATTGGGAA ATAGAAGCCAGTGAAGTGATGCTGTCCACTCGGATTGGGTCAGGCTCTTTTGGAACTGTTTATAAGGGTAAATGGCACGGAGATGTTGCA GTAAAGATCCTAAAGGTTGTCGACCCAACCCCAGAGCAATTCCAGGCCTTCAGGAATGAGGTGGCTGTTCTGCGCAAAACACGGCATGTG AACATTCTGCTTTTCATGGGGTACATGACAAAGGACAACCTGGCAATTGTGACCCAGTGGTGCGAGGGCAGCAGCCTCTACAAACACCTG CATGTCCAGGAGACCAAGTTTCAGATGTTCCAGCTAATTGACATTGCCCGGCAGACGGCTCAGGGAATGGACTATTTGCATGCAAAGAAC ATCATCCATAGAGACATGAAATCCAACAATATATTTCTCCATGAAGGCTTAACAGTGAAAATTGGAGATTTTGGTTTGGCAACAGTAAAG TCACGCTGGAGTGGTTCTCAGCAGGTTGAACAACCTACTGGCTCTGTCCTCTGGATGGCCCCAGAGGTGATCCGAATGCAGGATAACAAC CCATTCAGTTTCCAGTCGGATGTCTACTCCTATGGCATCGTATTGTATGAACTGATGACGGGGGAGCTTCCTTATTCTCACATCAACAAC CGAGATCAGATCATCTTCATGGTGGGCCGAGGATATGCCTCCCCAGATCTTAGTAAGCTATATAAGAACTGCCCCAAAGCAATGAAGAGG CTGGTAGCTGACTGTGTGAAGAAAGTAAAGGAAGAGAGGCCTCTTTTTCCCCAGATCCTGTCTTCCATTGAGCTGCTCCAACACTCTCTA CCGAAGATCAACCGGAGCGCTTCCGAGCCATCCTTGCATCGGGCAGCCCACACTGAGGATATCAATGCTTGCACGCTGACCACGTCCCCG AGGCTGCCTGTCTTCTAGTTGACTTTGCACCTGTCTTCAGGCTGCCAGGGGAGGAGGAGAAGCCAGCAGGCACCACTTTTCTGCTCCCTT TCTCCAGAGGCAGAACACATGTTTTCAGAGAAGCTGCTGCTAAGGACCTTCTAGACTGCTCACAGGGCCTTAACTTCATGTTGCCTTCTT TTCTATCCCTTTGGGCCCTGGGAGAAGGAAGCCATTTGCAGTGCTGGTGTGTCCTGCTCCCTCCCCACATTCCCCATGCTCAAGGCCCAG CCTTCTGTAGATGCGCAAGTGGATGTTGATGGTAGTACAAAAAGCAGGGGCCCAGCCCCAGCTGTTGGCTACATGAGTATTTAGAGGAAG TAAGGTAGCAGGCAGTCCAGCCCTGATGTGGAGACACATGGGATTTTGGAAATCAGCTTCTGGAGGAATGCATGTCACAGGCGGGACTTT CTTCAGAGAGTGGTGCAGCGCCAGACATTTTGCACATAAGGCACCAAACAGCCCAGGACTGCCGAGACTCTGGCCGCCCGAAGGAGCCTG CTTTGGTACTATGGAACTTTTCTTAGGGGACACGTCCTCCTTTCACAGCTTCTAAGGTGTCCAGTGCATTGGGATGGTTTTCCAGGCAAG GCACTCGGCCAATCCGCATCTCAGCCCTCTCAGGGAGCAGTCTTCCATCATGCTGAATTTTGTCTTCCAGGAGCTGCCCCTATGGGGCGG >In-frame_ENST00000341712_ENST00000442415_TCGA-D9-A4Z6-06A_MPRIP_chr17_17083402_+_RAF1_chr3_12641914_length(amino acids)=1385AA_start in transcript=0_stop in transcript=4157 MSAAKENPCRKFQANIFNKSKCQNCFKPRESHLLNDEDLTQAKPIYGGWLLLAPDGTDFDNPVHRSRKWQRRFFILYEHGLLRYALDEMP TTLPQGTINMNQCTDVVDGEGRTGQKFSLCILTPEKEHFIRAETKEIVSGWLEMLMVYPRTNKQNQKKKRKVEPPTPQEPGPAKVAVTSS SSSSSSSSSIPSAEKVPTTKSTLWQEEMRTKDQPDGSSLSPAQSPSQSQPPAASSLREPGLESKEEESAMSSDRMDCGRKVRVESGYFSL EKTKQDLKAEEQQLPPPLSPPSPSTPNHRRSQVIEKFEALDIEKAEHMETNAVGPSPSSDTRQGRSEKRAFPRKRDFTNEAPPAPLPDAS ASPLSPHRRAKSLDRRSTEPSVTPDLLNFKKGWLTKQYEDGQWKKHWFVLADQSLRYYRDSVAEEAADLDGEIDLSACYDVTEYPVQRNY GFQIHTKEGEFTLSAMTSGIRRNWIQTIMKHVHPTTAPDVTSSLPEEKNKSSCSFETCPRPTEKQEAELGEPDPEQKRSRARERRREGRS KTFDWAEFRPIQQALAQERVGGVGPADTHEPLRPEAEPGELERERARRREERRKRFGMLDATDGPGTEDAALRMEVDRSPGLPMSDLKTH NVHVEIEQRWHQVETTPLREEKQVPIAPVHLSSEDGGDRLSTHELTSLLEKELEQSQKEASDLLEQNRLLQDQLRVALGREQSAREGYVL QATCERGFAAMEETHQKKIEDLQRQHQRELEKLREEKDRLLAEETAATISAIEAMKNAHREEMERELEKSQRSQISSVNSDVEALRRQYL EELQSVQRELEVLSEQYSQKCLENAHLAQALEAERQALRQCQRENQELNAHNQELNNRLAAEITRLRTLLTGDGGGEATGSPLAQGKDAY ELEVLLRVKESEIQYLKQEISSLKDELQTALRDKKYASDKYKDIYTELSIAKAKADCDISRLKEQLKAATEALGEKSPDSATVSGYDIMK SKSNPDFLKKDRSCVTRQLRNIRSKDAIRSHSESASPSALSSSPNNLSPTGWSQPKTPVPAQRERAPVSGTQEKNKIRPRGQRDSSYYWE IEASEVMLSTRIGSGSFGTVYKGKWHGDVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYMTKDNLAIVTQWCEGSSLYKHL HVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNN PFSFQSDVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCVKKVKEERPLFPQILSSIELLQHSL -------------------------------------------------------------- >In-frame_ENST00000341712_ENST00000534997_TCGA-D9-A4Z6-06A_MPRIP_chr17_17083402_+_RAF1_chr3_12641914_length(transcript)=4405nt_BP=3045nt ATGTCGGCAGCCAAGGAGAACCCGTGCAGGAAATTCCAGGCCAACATCTTCAACAAGAGCAAGTGTCAGAACTGCTTCAAGCCCCGCGAG TCGCATCTGCTCAACGACGAGGACCTGACGCAGGCAAAACCCATTTATGGCGGTTGGCTGCTCCTGGCTCCAGATGGGACCGACTTTGAC AACCCAGTGCACCGGTCTCGGAAATGGCAGCGACGGTTCTTCATCCTTTACGAGCACGGCCTCTTGCGCTACGCCCTGGATGAGATGCCC ACGACCCTTCCTCAGGGCACCATCAACATGAACCAGTGCACAGATGTGGTGGATGGGGAGGGCCGCACGGGCCAGAAGTTCTCCCTGTGT ATTCTGACGCCTGAGAAGGAGCATTTCATCCGGGCGGAGACCAAGGAGATCGTCAGTGGGTGGCTGGAGATGCTCATGGTCTATCCCCGG ACCAACAAGCAGAATCAGAAGAAGAAACGGAAAGTGGAGCCCCCCACACCACAGGAGCCTGGGCCTGCCAAGGTGGCTGTTACCAGCAGC AGCAGCAGCAGCAGCAGCAGCAGCAGCATCCCCAGTGCTGAGAAAGTCCCCACCACCAAGTCCACACTCTGGCAGGAAGAAATGAGGACC AAGGACCAGCCAGATGGCAGCAGCCTGAGTCCAGCTCAGAGTCCCAGCCAGAGCCAGCCTCCTGCTGCCAGCTCCCTGCGGGAACCTGGG CTAGAGAGCAAAGAAGAGGAGAGCGCCATGAGTAGCGACCGCATGGACTGTGGCCGCAAAGTCCGGGTGGAGAGCGGCTACTTCTCTCTG GAGAAGACCAAACAGGACTTGAAGGCTGAAGAACAGCAGCTGCCCCCGCCGCTCTCCCCTCCCAGCCCCAGCACCCCCAACCACAGGAGG TCCCAGGTGATTGAAAAGTTTGAGGCCTTGGACATTGAGAAGGCAGAGCACATGGAGACCAATGCAGTGGGGCCCTCACCATCCAGCGAC ACACGCCAGGGCCGCAGCGAGAAGAGGGCGTTCCCTAGGAAGCGGGACTTCACCAATGAAGCCCCCCCAGCTCCTCTCCCAGACGCCTCG GCTTCCCCCCTGTCTCCACACCGAAGAGCCAAGTCACTGGACAGGAGGTCCACGGAGCCCTCCGTGACGCCCGACCTGCTGAATTTCAAG AAAGGCTGGCTGACTAAGCAGTATGAGGACGGCCAGTGGAAGAAACACTGGTTTGTCCTCGCCGATCAAAGCCTGAGATACTACAGGGAT TCAGTGGCTGAGGAGGCAGCCGACTTGGATGGAGAAATTGACTTGTCCGCATGTTACGATGTCACAGAGTATCCAGTTCAGAGAAACTAT GGCTTCCAGATACATACAAAGGAGGGCGAGTTTACCCTGTCGGCCATGACATCTGGGATTCGGCGGAACTGGATCCAGACCATCATGAAG CACGTGCACCCGACCACTGCCCCGGATGTGACCAGCTCGTTGCCAGAGGAAAAAAACAAGAGCAGCTGCTCTTTTGAGACCTGCCCGAGG CCTACTGAGAAGCAAGAGGCAGAGCTGGGGGAGCCGGACCCTGAGCAGAAGAGGAGCCGCGCACGGGAGCGGAGGCGAGAGGGCCGCTCC AAGACCTTTGACTGGGCTGAGTTCCGTCCCATCCAGCAGGCCCTGGCTCAGGAGCGGGTGGGCGGCGTGGGGCCTGCTGACACCCACGAG CCCCTGCGCCCTGAGGCGGAGCCTGGGGAGCTGGAGCGGGAGCGTGCACGGAGGCGGGAGGAGCGCCGCAAGCGCTTCGGGATGCTCGAC GCCACAGACGGGCCAGGCACTGAGGATGCAGCCCTGCGCATGGAGGTGGACCGGAGCCCAGGGCTGCCTATGAGCGACCTCAAAACGCAT AACGTCCACGTGGAGATTGAGCAGCGGTGGCATCAGGTGGAGACCACACCTCTCCGGGAAGAGAAGCAGGTGCCCATCGCCCCCGTCCAC CTGTCTTCTGAAGATGGGGGTGACCGGCTCTCCACACACGAGCTGACCTCTCTGCTCGAGAAGGAGCTGGAGCAGAGCCAGAAGGAGGCC TCAGACCTTCTGGAGCAGAACCGGCTCCTGCAGGACCAGCTGAGGGTGGCCCTGGGCCGGGAGCAGAGCGCCCGTGAGGGCTACGTGCTG CAGGCCACGTGCGAGCGAGGGTTTGCAGCAATGGAAGAAACGCACCAGAAGAAGATTGAAGATCTCCAGAGGCAGCACCAGCGGGAGCTA GAGAAACTTCGAGAAGAGAAAGACCGCCTCCTAGCCGAGGAGACAGCGGCCACCATCTCAGCCATCGAAGCCATGAAGAACGCCCACCGG GAGGAAATGGAGCGGGAGCTGGAGAAGAGCCAGCGGTCCCAGATCAGCAGCGTCAACTCGGATGTTGAGGCCCTGCGGCGCCAGTACCTG GAGGAGCTGCAGTCGGTGCAGCGGGAACTGGAGGTCCTCTCGGAGCAGTACTCGCAGAAGTGCCTGGAGAATGCCCATCTGGCCCAGGCG CTGGAGGCCGAGCGGCAGGCCCTGCGGCAGTGCCAGCGTGAGAACCAGGAGCTCAATGCCCACAACCAGGAGCTGAACAACCGCCTGGCT GCAGAGATCACACGGTTGCGGACGCTGCTGACTGGGGACGGCGGTGGGGAGGCCACTGGGTCACCCCTTGCACAGGGCAAGGATGCCTAT GAACTAGAGGTCTTATTGCGGGTAAAGGAATCGGAAATACAGTACCTGAAACAGGAGATTAGCTCCCTCAAGGATGAGCTGCAGACGGCA CTGCGGGACAAGAAGTACGCAAGTGACAAGTACAAAGACATCTACACAGAGCTCAGCATCGCGAAGGCTAAGGCTGACTGTGACATCAGC AGGTTGAAGGAGCAGCTCAAGGCTGCAACGGAAGCACTGGGGGAGAAGTCCCCTGACAGTGCCACGGTGTCCGGATATGATATAATGAAA TCTAAAAGCAACCCTGACTTCTTGAAGAAAGACAGATCCTGTGTCACCCGGCAACTCAGAAACATCAGGTCCAAGGATGCAATTCGAAGT CACAGCGAATCAGCCTCACCTTCAGCCCTGTCCAGTAGCCCCAACAATCTGAGCCCAACAGGCTGGTCACAGCCGAAAACCCCCGTGCCA GCACAAAGAGAGCGGGCACCAGTATCTGGGACCCAGGAGAAAAACAAAATTAGGCCTCGTGGACAGAGAGATTCAAGCTATTATTGGGAA ATAGAAGCCAGTGAAGTGATGCTGTCCACTCGGATTGGGTCAGGCTCTTTTGGAACTGTTTATAAGGGTAAATGGCACGGAGATGTTGCA GTAAAGATCCTAAAGGTTGTCGACCCAACCCCAGAGCAATTCCAGGCCTTCAGGAATGAGGTGGCTGTTCTGCGCAAAACACGGCATGTG AACATTCTGCTTTTCATGGGGTACATGACAAAGGACAACCTGGCAATTGTGACCCAGTGGTGCGAGGGCAGCAGCCTCTACAAACACCTG CATGTCCAGGAGACCAAGTTTCAGATGTTCCAGCTAATTGACATTGCCCGGCAGACGGCTCAGGGAATGGACTATTTGCATGCAAAGAAC ATCATCCATAGAGACATGAAATCCAACAATATATTTCTCCATGAAGGCTTAACAGTGAAAATTGGAGATTTTGGTTTGGCAACAGTAAAG TCACGCTGGAGTGGTTCTCAGCAGGTTGAACAACCTACTGGCTCTGTCCTCTGGATGGCCCCAGAGGTGATCCGAATGCAGGATAACAAC CCATTCAGTTTCCAGTCGGATGTCTACTCCTATGGCATCGTATTGTATGAACTGATGACGGGGGAGCTTCCTTATTCTCACATCAACAAC CGAGATCAGATCATCTTCATGGTGGGCCGAGGATATGCCTCCCCAGATCTTAGTAAGCTATATAAGAACTGCCCCAAAGCAATGAAGAGG CTGGTAGCTGACTGTGTGAAGAAAGTAAAGGAAGAGAGGCCTCTTTTTCCCCAGATCCTGTCTTCCATTGAGCTGCTCCAACACTCTCTA CCGAAGATCAACCGGAGCGCTTCCGAGCCATCCTTGCATCGGGCAGCCCACACTGAGGATATCAATGCTTGCACGCTGACCACGTCCCCG AGGCTGCCTGTCTTCTAGTTGACTTTGCACCTGTCTTCAGGCTGCCAGGGGAGGAGGAGAAGCCAGCAGGCACCACTTTTCTGCTCCCTT TCTCCAGAGGCAGAACACATGTTTTCAGAGAAGCTGCTGCTAAGGACCTTCTAGACTGCTCACAGGGCCTTAACTTCATGTTGCCTTCTT >In-frame_ENST00000341712_ENST00000534997_TCGA-D9-A4Z6-06A_MPRIP_chr17_17083402_+_RAF1_chr3_12641914_length(amino acids)=1385AA_start in transcript=0_stop in transcript=4157 MSAAKENPCRKFQANIFNKSKCQNCFKPRESHLLNDEDLTQAKPIYGGWLLLAPDGTDFDNPVHRSRKWQRRFFILYEHGLLRYALDEMP TTLPQGTINMNQCTDVVDGEGRTGQKFSLCILTPEKEHFIRAETKEIVSGWLEMLMVYPRTNKQNQKKKRKVEPPTPQEPGPAKVAVTSS SSSSSSSSSIPSAEKVPTTKSTLWQEEMRTKDQPDGSSLSPAQSPSQSQPPAASSLREPGLESKEEESAMSSDRMDCGRKVRVESGYFSL EKTKQDLKAEEQQLPPPLSPPSPSTPNHRRSQVIEKFEALDIEKAEHMETNAVGPSPSSDTRQGRSEKRAFPRKRDFTNEAPPAPLPDAS ASPLSPHRRAKSLDRRSTEPSVTPDLLNFKKGWLTKQYEDGQWKKHWFVLADQSLRYYRDSVAEEAADLDGEIDLSACYDVTEYPVQRNY GFQIHTKEGEFTLSAMTSGIRRNWIQTIMKHVHPTTAPDVTSSLPEEKNKSSCSFETCPRPTEKQEAELGEPDPEQKRSRARERRREGRS KTFDWAEFRPIQQALAQERVGGVGPADTHEPLRPEAEPGELERERARRREERRKRFGMLDATDGPGTEDAALRMEVDRSPGLPMSDLKTH NVHVEIEQRWHQVETTPLREEKQVPIAPVHLSSEDGGDRLSTHELTSLLEKELEQSQKEASDLLEQNRLLQDQLRVALGREQSAREGYVL QATCERGFAAMEETHQKKIEDLQRQHQRELEKLREEKDRLLAEETAATISAIEAMKNAHREEMERELEKSQRSQISSVNSDVEALRRQYL EELQSVQRELEVLSEQYSQKCLENAHLAQALEAERQALRQCQRENQELNAHNQELNNRLAAEITRLRTLLTGDGGGEATGSPLAQGKDAY ELEVLLRVKESEIQYLKQEISSLKDELQTALRDKKYASDKYKDIYTELSIAKAKADCDISRLKEQLKAATEALGEKSPDSATVSGYDIMK SKSNPDFLKKDRSCVTRQLRNIRSKDAIRSHSESASPSALSSSPNNLSPTGWSQPKTPVPAQRERAPVSGTQEKNKIRPRGQRDSSYYWE IEASEVMLSTRIGSGSFGTVYKGKWHGDVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYMTKDNLAIVTQWCEGSSLYKHL HVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNN PFSFQSDVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCVKKVKEERPLFPQILSSIELLQHSL -------------------------------------------------------------- >In-frame_ENST00000341712_ENST00000542177_TCGA-D9-A4Z6-06A_MPRIP_chr17_17083402_+_RAF1_chr3_12641914_length(transcript)=4339nt_BP=3045nt ATGTCGGCAGCCAAGGAGAACCCGTGCAGGAAATTCCAGGCCAACATCTTCAACAAGAGCAAGTGTCAGAACTGCTTCAAGCCCCGCGAG TCGCATCTGCTCAACGACGAGGACCTGACGCAGGCAAAACCCATTTATGGCGGTTGGCTGCTCCTGGCTCCAGATGGGACCGACTTTGAC AACCCAGTGCACCGGTCTCGGAAATGGCAGCGACGGTTCTTCATCCTTTACGAGCACGGCCTCTTGCGCTACGCCCTGGATGAGATGCCC ACGACCCTTCCTCAGGGCACCATCAACATGAACCAGTGCACAGATGTGGTGGATGGGGAGGGCCGCACGGGCCAGAAGTTCTCCCTGTGT ATTCTGACGCCTGAGAAGGAGCATTTCATCCGGGCGGAGACCAAGGAGATCGTCAGTGGGTGGCTGGAGATGCTCATGGTCTATCCCCGG ACCAACAAGCAGAATCAGAAGAAGAAACGGAAAGTGGAGCCCCCCACACCACAGGAGCCTGGGCCTGCCAAGGTGGCTGTTACCAGCAGC AGCAGCAGCAGCAGCAGCAGCAGCAGCATCCCCAGTGCTGAGAAAGTCCCCACCACCAAGTCCACACTCTGGCAGGAAGAAATGAGGACC AAGGACCAGCCAGATGGCAGCAGCCTGAGTCCAGCTCAGAGTCCCAGCCAGAGCCAGCCTCCTGCTGCCAGCTCCCTGCGGGAACCTGGG CTAGAGAGCAAAGAAGAGGAGAGCGCCATGAGTAGCGACCGCATGGACTGTGGCCGCAAAGTCCGGGTGGAGAGCGGCTACTTCTCTCTG GAGAAGACCAAACAGGACTTGAAGGCTGAAGAACAGCAGCTGCCCCCGCCGCTCTCCCCTCCCAGCCCCAGCACCCCCAACCACAGGAGG TCCCAGGTGATTGAAAAGTTTGAGGCCTTGGACATTGAGAAGGCAGAGCACATGGAGACCAATGCAGTGGGGCCCTCACCATCCAGCGAC ACACGCCAGGGCCGCAGCGAGAAGAGGGCGTTCCCTAGGAAGCGGGACTTCACCAATGAAGCCCCCCCAGCTCCTCTCCCAGACGCCTCG GCTTCCCCCCTGTCTCCACACCGAAGAGCCAAGTCACTGGACAGGAGGTCCACGGAGCCCTCCGTGACGCCCGACCTGCTGAATTTCAAG AAAGGCTGGCTGACTAAGCAGTATGAGGACGGCCAGTGGAAGAAACACTGGTTTGTCCTCGCCGATCAAAGCCTGAGATACTACAGGGAT TCAGTGGCTGAGGAGGCAGCCGACTTGGATGGAGAAATTGACTTGTCCGCATGTTACGATGTCACAGAGTATCCAGTTCAGAGAAACTAT GGCTTCCAGATACATACAAAGGAGGGCGAGTTTACCCTGTCGGCCATGACATCTGGGATTCGGCGGAACTGGATCCAGACCATCATGAAG CACGTGCACCCGACCACTGCCCCGGATGTGACCAGCTCGTTGCCAGAGGAAAAAAACAAGAGCAGCTGCTCTTTTGAGACCTGCCCGAGG CCTACTGAGAAGCAAGAGGCAGAGCTGGGGGAGCCGGACCCTGAGCAGAAGAGGAGCCGCGCACGGGAGCGGAGGCGAGAGGGCCGCTCC AAGACCTTTGACTGGGCTGAGTTCCGTCCCATCCAGCAGGCCCTGGCTCAGGAGCGGGTGGGCGGCGTGGGGCCTGCTGACACCCACGAG CCCCTGCGCCCTGAGGCGGAGCCTGGGGAGCTGGAGCGGGAGCGTGCACGGAGGCGGGAGGAGCGCCGCAAGCGCTTCGGGATGCTCGAC GCCACAGACGGGCCAGGCACTGAGGATGCAGCCCTGCGCATGGAGGTGGACCGGAGCCCAGGGCTGCCTATGAGCGACCTCAAAACGCAT AACGTCCACGTGGAGATTGAGCAGCGGTGGCATCAGGTGGAGACCACACCTCTCCGGGAAGAGAAGCAGGTGCCCATCGCCCCCGTCCAC CTGTCTTCTGAAGATGGGGGTGACCGGCTCTCCACACACGAGCTGACCTCTCTGCTCGAGAAGGAGCTGGAGCAGAGCCAGAAGGAGGCC TCAGACCTTCTGGAGCAGAACCGGCTCCTGCAGGACCAGCTGAGGGTGGCCCTGGGCCGGGAGCAGAGCGCCCGTGAGGGCTACGTGCTG CAGGCCACGTGCGAGCGAGGGTTTGCAGCAATGGAAGAAACGCACCAGAAGAAGATTGAAGATCTCCAGAGGCAGCACCAGCGGGAGCTA GAGAAACTTCGAGAAGAGAAAGACCGCCTCCTAGCCGAGGAGACAGCGGCCACCATCTCAGCCATCGAAGCCATGAAGAACGCCCACCGG GAGGAAATGGAGCGGGAGCTGGAGAAGAGCCAGCGGTCCCAGATCAGCAGCGTCAACTCGGATGTTGAGGCCCTGCGGCGCCAGTACCTG GAGGAGCTGCAGTCGGTGCAGCGGGAACTGGAGGTCCTCTCGGAGCAGTACTCGCAGAAGTGCCTGGAGAATGCCCATCTGGCCCAGGCG CTGGAGGCCGAGCGGCAGGCCCTGCGGCAGTGCCAGCGTGAGAACCAGGAGCTCAATGCCCACAACCAGGAGCTGAACAACCGCCTGGCT GCAGAGATCACACGGTTGCGGACGCTGCTGACTGGGGACGGCGGTGGGGAGGCCACTGGGTCACCCCTTGCACAGGGCAAGGATGCCTAT GAACTAGAGGTCTTATTGCGGGTAAAGGAATCGGAAATACAGTACCTGAAACAGGAGATTAGCTCCCTCAAGGATGAGCTGCAGACGGCA CTGCGGGACAAGAAGTACGCAAGTGACAAGTACAAAGACATCTACACAGAGCTCAGCATCGCGAAGGCTAAGGCTGACTGTGACATCAGC AGGTTGAAGGAGCAGCTCAAGGCTGCAACGGAAGCACTGGGGGAGAAGTCCCCTGACAGTGCCACGGTGTCCGGATATGATATAATGAAA TCTAAAAGCAACCCTGACTTCTTGAAGAAAGACAGATCCTGTGTCACCCGGCAACTCAGAAACATCAGGTCCAAGGATGCAATTCGAAGT CACAGCGAATCAGCCTCACCTTCAGCCCTGTCCAGTAGCCCCAACAATCTGAGCCCAACAGGCTGGTCACAGCCGAAAACCCCCGTGCCA GCACAAAGAGAGCGGGCACCAGTATCTGGGACCCAGGAGAAAAACAAAATTAGGCCTCGTGGACAGAGAGATTCAAGCTATTATTGGGAA ATAGAAGCCAGTGAAGTGATGCTGTCCACTCGGATTGGGTCAGGCTCTTTTGGAACTGTTTATAAGGGTAAATGGCACGGAGATGTTGCA GTAAAGATCCTAAAGGTTGTCGACCCAACCCCAGAGCAATTCCAGGCCTTCAGGAATGAGGTGGCTGTTCTGCGCAAAACACGGCATGTG AACATTCTGCTTTTCATGGGGTACATGACAAAGGACAACCTGGCAATTGTGACCCAGTGGTGCGAGGGCAGCAGCCTCTACAAACACCTG CATGTCCAGGAGACCAAGTTTCAGATGTTCCAGCTAATTGACATTGCCCGGCAGACGGCTCAGGGAATGGACTATTTGCATGCAAAGAAC ATCATCCATAGAGACATGAAATCCAACAATATATTTCTCCATGAAGGCTTAACAGTGAAAATTGGAGATTTTGGTTTGGCAACAGTAAAG TCACGCTGGAGTGGTTCTCAGCAGGTTGAACAACCTACTGGCTCTGTCCTCTGGATGGCCCCAGAGGTGATCCGAATGCAGGATAACAAC CCATTCAGTTTCCAGTCGGATGTCTACTCCTATGGCATCGTATTGTATGAACTGATGACGGGGGAGCTTCCTTATTCTCACATCAACAAC CGAGATCAGATCATCTTCATGGTGGGCCGAGGATATGCCTCCCCAGATCTTAGTAAGCTATATAAGAACTGCCCCAAAGCAATGAAGAGG CTGGTAGCTGACTGTGTGAAGAAAGTAAAGGAAGAGAGGCCTCTTTTTCCCCAGATCCTGTCTTCCATTGAGCTGCTCCAACACTCTCTA CCGAAGATCAACCGGAGCGCTTCCGAGCCATCCTTGCATCGGGCAGCCCACACTGAGGATATCAATGCTTGCACGCTGACCACGTCCCCG AGGCTGCCTGTCTTCTAGTTGACTTTGCACCTGTCTTCAGGCTGCCAGGGGAGGAGGAGAAGCCAGCAGGCACCACTTTTCTGCTCCCTT TCTCCAGAGGCAGAACACATGTTTTCAGAGAAGCTGCTGCTAAGGACCTTCTAGACTGCTCACAGGGCCTTAACTTCATGTTGCCTTCTT >In-frame_ENST00000341712_ENST00000542177_TCGA-D9-A4Z6-06A_MPRIP_chr17_17083402_+_RAF1_chr3_12641914_length(amino acids)=1385AA_start in transcript=0_stop in transcript=4157 MSAAKENPCRKFQANIFNKSKCQNCFKPRESHLLNDEDLTQAKPIYGGWLLLAPDGTDFDNPVHRSRKWQRRFFILYEHGLLRYALDEMP TTLPQGTINMNQCTDVVDGEGRTGQKFSLCILTPEKEHFIRAETKEIVSGWLEMLMVYPRTNKQNQKKKRKVEPPTPQEPGPAKVAVTSS SSSSSSSSSIPSAEKVPTTKSTLWQEEMRTKDQPDGSSLSPAQSPSQSQPPAASSLREPGLESKEEESAMSSDRMDCGRKVRVESGYFSL EKTKQDLKAEEQQLPPPLSPPSPSTPNHRRSQVIEKFEALDIEKAEHMETNAVGPSPSSDTRQGRSEKRAFPRKRDFTNEAPPAPLPDAS ASPLSPHRRAKSLDRRSTEPSVTPDLLNFKKGWLTKQYEDGQWKKHWFVLADQSLRYYRDSVAEEAADLDGEIDLSACYDVTEYPVQRNY GFQIHTKEGEFTLSAMTSGIRRNWIQTIMKHVHPTTAPDVTSSLPEEKNKSSCSFETCPRPTEKQEAELGEPDPEQKRSRARERRREGRS KTFDWAEFRPIQQALAQERVGGVGPADTHEPLRPEAEPGELERERARRREERRKRFGMLDATDGPGTEDAALRMEVDRSPGLPMSDLKTH NVHVEIEQRWHQVETTPLREEKQVPIAPVHLSSEDGGDRLSTHELTSLLEKELEQSQKEASDLLEQNRLLQDQLRVALGREQSAREGYVL QATCERGFAAMEETHQKKIEDLQRQHQRELEKLREEKDRLLAEETAATISAIEAMKNAHREEMERELEKSQRSQISSVNSDVEALRRQYL EELQSVQRELEVLSEQYSQKCLENAHLAQALEAERQALRQCQRENQELNAHNQELNNRLAAEITRLRTLLTGDGGGEATGSPLAQGKDAY ELEVLLRVKESEIQYLKQEISSLKDELQTALRDKKYASDKYKDIYTELSIAKAKADCDISRLKEQLKAATEALGEKSPDSATVSGYDIMK SKSNPDFLKKDRSCVTRQLRNIRSKDAIRSHSESASPSALSSSPNNLSPTGWSQPKTPVPAQRERAPVSGTQEKNKIRPRGQRDSSYYWE IEASEVMLSTRIGSGSFGTVYKGKWHGDVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYMTKDNLAIVTQWCEGSSLYKHL HVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNN PFSFQSDVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCVKKVKEERPLFPQILSSIELLQHSL -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for MPRIP-RAF1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| Hgene | MPRIP | chr17:17083402 | chr3:12641914 | ENST00000341712 | + | 22 | 24 | 2_383 | 1015.0 | 1231.0 | F-actin |
| Hgene | MPRIP | chr17:17083402 | chr3:12641914 | ENST00000395804 | + | 22 | 23 | 2_383 | 1015.0 | 1026.0 | F-actin |
| Hgene | MPRIP | chr17:17083402 | chr3:12641914 | ENST00000395811 | + | 22 | 23 | 2_383 | 1015.0 | 1039.0 | F-actin |
| Hgene | MPRIP | chr17:17083402 | chr3:12641914 | ENST00000444976 | + | 21 | 22 | 2_383 | 977.0 | 1001.0 | F-actin |
| Hgene | MPRIP | chr17:17083402 | chr3:12641914 | ENST00000341712 | + | 22 | 24 | 824_879 | 1015.0 | 1231.0 | PPP1R12A |
| Hgene | MPRIP | chr17:17083402 | chr3:12641914 | ENST00000395804 | + | 22 | 23 | 824_879 | 1015.0 | 1026.0 | PPP1R12A |
| Hgene | MPRIP | chr17:17083402 | chr3:12641914 | ENST00000395811 | + | 22 | 23 | 824_879 | 1015.0 | 1039.0 | PPP1R12A |
| Hgene | MPRIP | chr17:17083402 | chr3:12641914 | ENST00000444976 | + | 21 | 22 | 824_879 | 977.0 | 1001.0 | PPP1R12A |
| Hgene | MPRIP | chr17:17083402 | chr3:12641914 | ENST00000341712 | + | 22 | 24 | 546_824 | 1015.0 | 1231.0 | RHOA |
| Hgene | MPRIP | chr17:17083402 | chr3:12641914 | ENST00000395804 | + | 22 | 23 | 546_824 | 1015.0 | 1026.0 | RHOA |
| Hgene | MPRIP | chr17:17083402 | chr3:12641914 | ENST00000395811 | + | 22 | 23 | 546_824 | 1015.0 | 1039.0 | RHOA |
| Hgene | MPRIP | chr17:17083402 | chr3:12641914 | ENST00000444976 | + | 21 | 22 | 546_824 | 977.0 | 1001.0 | RHOA |
| Tgene | RAF1 | chr17:17083402 | chr3:12641914 | ENST00000251849 | 6 | 17 | 331_349 | 278.0 | 649.0 | PEBP1/RKIP | |
| Tgene | RAF1 | chr17:17083402 | chr3:12641914 | ENST00000442415 | 7 | 18 | 331_349 | 298.0 | 669.0 | PEBP1/RKIP |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for MPRIP-RAF1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| Tgene | RAF1 | P04049 | DB08896 | Regorafenib | Inhibitor | Small molecule | Approved |
| Tgene | RAF1 | P04049 | DB08896 | Regorafenib | Inhibitor | Small molecule | Approved |
| Tgene | RAF1 | P04049 | DB00398 | Sorafenib | Inhibitor | Small molecule | Approved|Investigational |
| Tgene | RAF1 | P04049 | DB00398 | Sorafenib | Inhibitor | Small molecule | Approved|Investigational |
| Tgene | RAF1 | P04049 | DB08862 | Cholecystokinin | Agonist | Small molecule | Approved|Investigational |
| Tgene | RAF1 | P04049 | DB08862 | Cholecystokinin | Agonist | Small molecule | Approved|Investigational |
| Tgene | RAF1 | P04049 | DB08912 | Dabrafenib | Antagonist|Inhibitor | Small molecule | Approved|Investigational |
| Tgene | RAF1 | P04049 | DB08912 | Dabrafenib | Antagonist|Inhibitor | Small molecule | Approved|Investigational |
| Tgene | RAF1 | P04049 | DB12010 | Fostamatinib | Inhibitor | Small molecule | Approved|Investigational |
| Tgene | RAF1 | P04049 | DB12010 | Fostamatinib | Inhibitor | Small molecule | Approved|Investigational |
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Related Diseases for MPRIP-RAF1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | MPRIP | C0043094 | Weight Gain | 1 | CTD_human |
| Hgene | MPRIP | C3495676 | Anorectal Malformations | 1 | GENOMICS_ENGLAND |
| Tgene | RAF1 | C0028326 | Noonan Syndrome | 10 | CLINGEN;CTD_human;GENOMICS_ENGLAND;ORPHANET |
| Tgene | RAF1 | C0175704 | LEOPARD Syndrome | 7 | CLINGEN;CTD_human;GENOMICS_ENGLAND |
| Tgene | RAF1 | C1969057 | Noonan Syndrome 5 | 4 | CTD_human;GENOMICS_ENGLAND;UNIPROT |
| Tgene | RAF1 | C1969056 | LEOPARD SYNDROME 2 | 3 | CTD_human;GENOMICS_ENGLAND;UNIPROT |
| Tgene | RAF1 | C0007194 | Hypertrophic Cardiomyopathy | 2 | CTD_human |
| Tgene | RAF1 | C0041409 | Turner Syndrome, Male | 2 | CTD_human |
| Tgene | RAF1 | C1519086 | Pilomyxoid astrocytoma | 2 | ORPHANET |
| Tgene | RAF1 | C1527404 | Female Pseudo-Turner Syndrome | 2 | CTD_human |
| Tgene | RAF1 | C4551472 | Hypertrophic obstructive cardiomyopathy | 2 | CTD_human |
| Tgene | RAF1 | C4551602 | Noonan Syndrome 1 | 2 | CTD_human |
| Tgene | RAF1 | C0006142 | Malignant neoplasm of breast | 1 | CTD_human |
| Tgene | RAF1 | C0007131 | Non-Small Cell Lung Carcinoma | 1 | CTD_human |
| Tgene | RAF1 | C0007193 | Cardiomyopathy, Dilated | 1 | CTD_human |
| Tgene | RAF1 | C0017638 | Glioma | 1 | CTD_human |
| Tgene | RAF1 | C0020429 | Hyperalgesia | 1 | CTD_human |
| Tgene | RAF1 | C0022665 | Kidney Neoplasm | 1 | CTD_human |
| Tgene | RAF1 | C0023903 | Liver neoplasms | 1 | CTD_human |
| Tgene | RAF1 | C0024121 | Lung Neoplasms | 1 | CTD_human |
| Tgene | RAF1 | C0242379 | Malignant neoplasm of lung | 1 | CTD_human |
| Tgene | RAF1 | C0259783 | mixed gliomas | 1 | CTD_human |
| Tgene | RAF1 | C0340427 | Familial dilated cardiomyopathy | 1 | ORPHANET |
| Tgene | RAF1 | C0345904 | Malignant neoplasm of liver | 1 | CTD_human |
| Tgene | RAF1 | C0345967 | Malignant mesothelioma | 1 | CTD_human |
| Tgene | RAF1 | C0458247 | Allodynia | 1 | CTD_human |
| Tgene | RAF1 | C0555198 | Malignant Glioma | 1 | CTD_human |
| Tgene | RAF1 | C0587248 | Costello syndrome (disorder) | 1 | CLINGEN |
| Tgene | RAF1 | C0678222 | Breast Carcinoma | 1 | CTD_human |
| Tgene | RAF1 | C0740457 | Malignant neoplasm of kidney | 1 | CTD_human |
| Tgene | RAF1 | C0751211 | Hyperalgesia, Primary | 1 | CTD_human |
| Tgene | RAF1 | C0751212 | Hyperalgesia, Secondary | 1 | CTD_human |
| Tgene | RAF1 | C0751213 | Tactile Allodynia | 1 | CTD_human |
| Tgene | RAF1 | C0751214 | Hyperalgesia, Thermal | 1 | CTD_human |
| Tgene | RAF1 | C1257931 | Mammary Neoplasms, Human | 1 | CTD_human |
| Tgene | RAF1 | C1275081 | Cardio-facio-cutaneous syndrome | 1 | CLINGEN |
| Tgene | RAF1 | C1449563 | Cardiomyopathy, Familial Idiopathic | 1 | CTD_human |
| Tgene | RAF1 | C1458155 | Mammary Neoplasms | 1 | CTD_human |
| Tgene | RAF1 | C2936719 | Mechanical Allodynia | 1 | CTD_human |
| Tgene | RAF1 | C4014656 | CARDIOMYOPATHY, DILATED, 1NN | 1 | CTD_human;UNIPROT |
| Tgene | RAF1 | C4551484 | Leopard Syndrome 1 | 1 | CTD_human;GENOMICS_ENGLAND |
| Tgene | RAF1 | C4704874 | Mammary Carcinoma, Human | 1 | CTD_human |
| Tgene | RAF1 | C4721610 | Carcinoma, Ovarian Epithelial | 1 | CTD_human |
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