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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:MRPS25-VAT1 (FusionGDB2 ID:54850) |
Fusion Gene Summary for MRPS25-VAT1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: MRPS25-VAT1 | Fusion gene ID: 54850 | Hgene | Tgene | Gene symbol | MRPS25 | VAT1 | Gene ID | 64432 | 10493 |
| Gene name | mitochondrial ribosomal protein S25 | vesicle amine transport 1 | |
| Synonyms | MRP-S25|RPMS25 | VATI | |
| Cytomap | 3p25.1 | 17q21.31 | |
| Type of gene | protein-coding | protein-coding | |
| Description | 28S ribosomal protein S25, mitochondrialS25mtmitochondrial 28S ribosomal protein S25mitochondrial small ribosomal subunit protein mS25 | synaptic vesicle membrane protein VAT-1 homologmembrane protein of cholinergic synaptic vesiclesvesicle amine transport protein 1 homolog (T. californica) | |
| Modification date | 20200315 | 20200313 | |
| UniProtAcc | P82663 | . | |
| Ensembl transtripts involved in fusion gene | ENST00000496484, ENST00000253686, ENST00000449354, ENST00000444840, | ENST00000355653, ENST00000587173, ENST00000420567, | |
| Fusion gene scores | * DoF score | 3 X 3 X 1=9 | 11 X 11 X 4=484 |
| # samples | 3 | 12 | |
| ** MAII score | log2(3/9*10)=1.73696559416621 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(12/484*10)=-2.01197264166608 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: MRPS25 [Title/Abstract] AND VAT1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | MRPS25(15100875)-VAT1(41170225), # samples:1 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene breakpoints across MRPS25 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
| Fusion gene breakpoints across VAT1 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS5.0 | N/A | DA642154 | MRPS25 | chr3 | 15100875 | - | VAT1 | chr17 | 41170225 | - |
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Fusion Gene ORF analysis for MRPS25-VAT1 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3CDS | ENST00000496484 | ENST00000355653 | MRPS25 | chr3 | 15100875 | - | VAT1 | chr17 | 41170225 | - |
| intron-3CDS | ENST00000496484 | ENST00000587173 | MRPS25 | chr3 | 15100875 | - | VAT1 | chr17 | 41170225 | - |
| intron-3CDS | ENST00000496484 | ENST00000420567 | MRPS25 | chr3 | 15100875 | - | VAT1 | chr17 | 41170225 | - |
| In-frame | ENST00000253686 | ENST00000355653 | MRPS25 | chr3 | 15100875 | - | VAT1 | chr17 | 41170225 | - |
| In-frame | ENST00000253686 | ENST00000587173 | MRPS25 | chr3 | 15100875 | - | VAT1 | chr17 | 41170225 | - |
| In-frame | ENST00000253686 | ENST00000420567 | MRPS25 | chr3 | 15100875 | - | VAT1 | chr17 | 41170225 | - |
| In-frame | ENST00000449354 | ENST00000355653 | MRPS25 | chr3 | 15100875 | - | VAT1 | chr17 | 41170225 | - |
| In-frame | ENST00000449354 | ENST00000587173 | MRPS25 | chr3 | 15100875 | - | VAT1 | chr17 | 41170225 | - |
| In-frame | ENST00000449354 | ENST00000420567 | MRPS25 | chr3 | 15100875 | - | VAT1 | chr17 | 41170225 | - |
| In-frame | ENST00000444840 | ENST00000355653 | MRPS25 | chr3 | 15100875 | - | VAT1 | chr17 | 41170225 | - |
| In-frame | ENST00000444840 | ENST00000587173 | MRPS25 | chr3 | 15100875 | - | VAT1 | chr17 | 41170225 | - |
| In-frame | ENST00000444840 | ENST00000420567 | MRPS25 | chr3 | 15100875 | - | VAT1 | chr17 | 41170225 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000253686 | MRPS25 | chr3 | 15100875 | - | ENST00000355653 | VAT1 | chr17 | 41170225 | - | 2425 | 382 | 141 | 968 | 275 |
| ENST00000253686 | MRPS25 | chr3 | 15100875 | - | ENST00000587173 | VAT1 | chr17 | 41170225 | - | 1131 | 382 | 141 | 968 | 275 |
| ENST00000253686 | MRPS25 | chr3 | 15100875 | - | ENST00000420567 | VAT1 | chr17 | 41170225 | - | 1112 | 382 | 141 | 968 | 275 |
| ENST00000449354 | MRPS25 | chr3 | 15100875 | - | ENST00000355653 | VAT1 | chr17 | 41170225 | - | 2350 | 307 | 66 | 893 | 275 |
| ENST00000449354 | MRPS25 | chr3 | 15100875 | - | ENST00000587173 | VAT1 | chr17 | 41170225 | - | 1056 | 307 | 66 | 893 | 275 |
| ENST00000449354 | MRPS25 | chr3 | 15100875 | - | ENST00000420567 | VAT1 | chr17 | 41170225 | - | 1037 | 307 | 66 | 893 | 275 |
| ENST00000444840 | MRPS25 | chr3 | 15100875 | - | ENST00000355653 | VAT1 | chr17 | 41170225 | - | 2407 | 364 | 123 | 950 | 275 |
| ENST00000444840 | MRPS25 | chr3 | 15100875 | - | ENST00000587173 | VAT1 | chr17 | 41170225 | - | 1113 | 364 | 123 | 950 | 275 |
| ENST00000444840 | MRPS25 | chr3 | 15100875 | - | ENST00000420567 | VAT1 | chr17 | 41170225 | - | 1094 | 364 | 123 | 950 | 275 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000253686 | ENST00000355653 | MRPS25 | chr3 | 15100875 | - | VAT1 | chr17 | 41170225 | - | 0.001897193 | 0.99810284 |
| ENST00000253686 | ENST00000587173 | MRPS25 | chr3 | 15100875 | - | VAT1 | chr17 | 41170225 | - | 0.002545362 | 0.9974546 |
| ENST00000253686 | ENST00000420567 | MRPS25 | chr3 | 15100875 | - | VAT1 | chr17 | 41170225 | - | 0.002250627 | 0.9977494 |
| ENST00000449354 | ENST00000355653 | MRPS25 | chr3 | 15100875 | - | VAT1 | chr17 | 41170225 | - | 0.001701681 | 0.99829835 |
| ENST00000449354 | ENST00000587173 | MRPS25 | chr3 | 15100875 | - | VAT1 | chr17 | 41170225 | - | 0.002215506 | 0.99778455 |
| ENST00000449354 | ENST00000420567 | MRPS25 | chr3 | 15100875 | - | VAT1 | chr17 | 41170225 | - | 0.001849593 | 0.9981504 |
| ENST00000444840 | ENST00000355653 | MRPS25 | chr3 | 15100875 | - | VAT1 | chr17 | 41170225 | - | 0.001620287 | 0.9983797 |
| ENST00000444840 | ENST00000587173 | MRPS25 | chr3 | 15100875 | - | VAT1 | chr17 | 41170225 | - | 0.002508252 | 0.9974917 |
| ENST00000444840 | ENST00000420567 | MRPS25 | chr3 | 15100875 | - | VAT1 | chr17 | 41170225 | - | 0.002194517 | 0.99780554 |
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Fusion Genomic Features for MRPS25-VAT1 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for MRPS25-VAT1 |
| Go to FGviewer for the breakpoints of chr3:15100875-chr17:41170225 - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| MRPS25 | . |
| FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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Fusion Gene Sequence for MRPS25-VAT1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >In-frame_ENST00000253686_ENST00000355653_DA642154_MRPS25_chr3_15100875_-_VAT1_chr17_41170225_length(transcript)=2425nt_BP=382nt AGCGTCTCCTGTGCGTCTGCGCGGGAAGTGGAACCTGGCTCTGGGGAGAAGCCGCGTGAGATCCGCGCGGGTGCTAGCTAGTCCTTTCTC GTCGCTGCTCGGCTCGCGGCCCGTGGGGTCGGCCCCGCCACCGTTGCCGCCATGCCCATGAAGGGCCGCTTCCCCATCCGCCGCACCCTG CAATATCTGAGCCAGGGGAACGTGGTGTTCAAGGACTCCGTGAAGGTCATGACAGTGAATTACAACACGCATGGGGAGCTGGGCGAGGGC GCCAGGAAGTTTGTGTTTTTCAACATACCTCAGATTCAATACAAAAACCCTTGGGTGCAGATCATGATGTTTAAGAACATGACGCCGTCA CCCTTCCTGCGATTCTACTTAGGGGGTGTGGGTATGGCTGCCGTGCAGCTGTGCCGTACAGTGGAGAATGTGACAGTGTTCGGAACGGCC TCGGCCAGCAAGCACGAGGCACTGAAGGAGAATGGGGTCACACATCCCATCGACTATCACACGACTGACTACGTGGATGAGATCAAGAAG ATTTCCCCTAAAGGAGTGGACATTGTCATGGACCCTCTGGGTGGGTCAGATACTGCCAAGGGCTACAACCTCCTGAAACCCATGGGCAAA GTCGTCACCTATGGAATGGCCAACCTGCTGACGGGCCCCAAACGGAACCTGATGGCCCTGGCCCGGACATGGTGGAATCAGTTCAGCGTG ACAGCTCTGCAGCTGCTGCAGGCCAACCGGGCTGTGTGTGGCTTCCACCTGGGCTACCTGGATGGTGAGGTGGAGCTGGTCAGTGGTGTG GTGGCCCGCCTCCTGGCTCTGTACAACCAGGGCCACATCAAGCCCCACATTGACTCAGTCTGGCCCTTCGAGAAGGTGGCTGATGCCATG AAACAGATGCAGGAGAAGAAGAATGTGGGCAAGGTCCTCCTGGTTCCAGGGCCAGAGAAGGAGAACTAGGGCAAGTGGCTGTGAGACCCT AGAGACCAGCGAAGGGAGAAGTTGGGAAGCTACGTTCTGTTGGCCACCAGACTTGCATTTCAGCCTCTGTCATAATGCTCTGCCCTCCCT CCCCCGAAGGTCTCTGTGGTGATGACCGCTCTCCCCTGCCCCTCCCCGCTTCCTGACCTCTGAAGAGGTTGGGAAGTGACCATTTGGATG TCTGGGCCCTGCCAAGGCGACAGGGAGGGTCAGAGGGAGGCCGGCTGCTTCCTGCCCCCACCCTTTCCCCGGGCCTGCTGTGCTGCTTTT GTGCCAAGGTTAGCCAGTCCCCCCTGTTGTGTTCCATGTGCTTTCACCTCTGCCTCATCTTTCCTCCCGTCCCTGCCCCGCCACCTCCCC AAAGAATTGAAACGTCAGCTCAGGATATGGGGCCAATCTCTGTGAGTCCAGCATGTACCTGTCTCTCCCTAGTGTCCCTTCAGCCTGGGC TGACCAGTGCCCGCCTCTGGGCTTGACCAGTTCCCAATCTCGTCCTCTGTCCCCAACTTCTTAAGCACAATTGGGCTTCTTCCATCTCCA GGTTTTCTGCCATTCTTAACCAAGGCTGCCTCTTCCAACAGGGCGGGAATCAGACCTACTCCCCTAGGTCACAACTCTGGGAAGGATACA GAGCCCCCACCCTTCACTGAGTTCTCTGGATTTGTTCTCAGTGCCTTAGCAACGAAAACCTGTGCTTGTGTGTGTGTGGCGGCGGGGAGG GAGGATCCTGTTTCCCACCTCCTTCTCCTCCCCTGTACTCCCCAGTGCCTTCCTTGTTCTGGTGGAGCTGGGGTTTCTCTCCTCCCCAGT CCCACAACACTGCCAAAAATCTGTGTATGTGCCATTGGGTGGGGCAGCCCCAAGCCTCCTGGGGAGGCAGGGCAAAAACAGGTGCCCTCA TCGTGGTCTGTGCCATGTCCCGTCTCTATGGTGGTTGAGGAGAAAGGCGGGGAAGCTTCCTCAGCCTTGCAGATATGTGTGGCATTTACT AGCCAGAGCTCTGAAAGGCAGTGCTGTCTGTTTCTTGTACTGGGACCAAAGTAAAAATCCAAGCACATTCCCCTTGCAGTTAGGGGAGGC CCTACTGCCTTCTCAAAGCAGAGAGGCAGCTTATCAAACTCAGCCCAAAACTCTGTTTACATGGGTGGGGAGATGGAGCAGGGAAGTACA GAGTGGGATGGTCAGGACCTGGGCCATTGCAACCAAAATGGGGACTTCCTGGGTAGGGAGGTCACTCCCTCTACTCACTGAGCTAGGATT AGGGAGGGTTATTGCCCCAACCATTGCAATGGGAGGTGGAGGGACAGGCTCAGCCTCCTCATTGTCTAAATGAGGCCTAAATGTGTGAAG >In-frame_ENST00000253686_ENST00000355653_DA642154_MRPS25_chr3_15100875_-_VAT1_chr17_41170225_length(amino acids)=275AA_start in transcript=141_stop in transcript=968 MPMKGRFPIRRTLQYLSQGNVVFKDSVKVMTVNYNTHGELGEGARKFVFFNIPQIQYKNPWVQIMMFKNMTPSPFLRFYLGGVGMAAVQL CRTVENVTVFGTASASKHEALKENGVTHPIDYHTTDYVDEIKKISPKGVDIVMDPLGGSDTAKGYNLLKPMGKVVTYGMANLLTGPKRNL MALARTWWNQFSVTALQLLQANRAVCGFHLGYLDGEVELVSGVVARLLALYNQGHIKPHIDSVWPFEKVADAMKQMQEKKNVGKVLLVPG -------------------------------------------------------------- >In-frame_ENST00000253686_ENST00000587173_DA642154_MRPS25_chr3_15100875_-_VAT1_chr17_41170225_length(transcript)=1131nt_BP=382nt AGCGTCTCCTGTGCGTCTGCGCGGGAAGTGGAACCTGGCTCTGGGGAGAAGCCGCGTGAGATCCGCGCGGGTGCTAGCTAGTCCTTTCTC GTCGCTGCTCGGCTCGCGGCCCGTGGGGTCGGCCCCGCCACCGTTGCCGCCATGCCCATGAAGGGCCGCTTCCCCATCCGCCGCACCCTG CAATATCTGAGCCAGGGGAACGTGGTGTTCAAGGACTCCGTGAAGGTCATGACAGTGAATTACAACACGCATGGGGAGCTGGGCGAGGGC GCCAGGAAGTTTGTGTTTTTCAACATACCTCAGATTCAATACAAAAACCCTTGGGTGCAGATCATGATGTTTAAGAACATGACGCCGTCA CCCTTCCTGCGATTCTACTTAGGGGGTGTGGGTATGGCTGCCGTGCAGCTGTGCCGTACAGTGGAGAATGTGACAGTGTTCGGAACGGCC TCGGCCAGCAAGCACGAGGCACTGAAGGAGAATGGGGTCACACATCCCATCGACTATCACACGACTGACTACGTGGATGAGATCAAGAAG ATTTCCCCTAAAGGAGTGGACATTGTCATGGACCCTCTGGGTGGGTCAGATACTGCCAAGGGCTACAACCTCCTGAAACCCATGGGCAAA GTCGTCACCTATGGAATGGCCAACCTGCTGACGGGCCCCAAACGGAACCTGATGGCCCTGGCCCGGACATGGTGGAATCAGTTCAGCGTG ACAGCTCTGCAGCTGCTGCAGGCCAACCGGGCTGTGTGTGGCTTCCACCTGGGCTACCTGGATGGTGAGGTGGAGCTGGTCAGTGGTGTG GTGGCCCGCCTCCTGGCTCTGTACAACCAGGGCCACATCAAGCCCCACATTGACTCAGTCTGGCCCTTCGAGAAGGTGGCTGATGCCATG AAACAGATGCAGGAGAAGAAGAATGTGGGCAAGGTCCTCCTGGTTCCAGGGCCAGAGAAGGAGAACTAGGGCAAGTGGCTGTGAGACCCT AGAGACCAGCGAAGGGAGAAGTTGGGAAGCTACGTTCTGTTGGCCACCAGACTTGCATTTCAGCCTCTGTCATAATGCTCTGCCCTCCCT >In-frame_ENST00000253686_ENST00000587173_DA642154_MRPS25_chr3_15100875_-_VAT1_chr17_41170225_length(amino acids)=275AA_start in transcript=141_stop in transcript=968 MPMKGRFPIRRTLQYLSQGNVVFKDSVKVMTVNYNTHGELGEGARKFVFFNIPQIQYKNPWVQIMMFKNMTPSPFLRFYLGGVGMAAVQL CRTVENVTVFGTASASKHEALKENGVTHPIDYHTTDYVDEIKKISPKGVDIVMDPLGGSDTAKGYNLLKPMGKVVTYGMANLLTGPKRNL MALARTWWNQFSVTALQLLQANRAVCGFHLGYLDGEVELVSGVVARLLALYNQGHIKPHIDSVWPFEKVADAMKQMQEKKNVGKVLLVPG -------------------------------------------------------------- >In-frame_ENST00000253686_ENST00000420567_DA642154_MRPS25_chr3_15100875_-_VAT1_chr17_41170225_length(transcript)=1112nt_BP=382nt AGCGTCTCCTGTGCGTCTGCGCGGGAAGTGGAACCTGGCTCTGGGGAGAAGCCGCGTGAGATCCGCGCGGGTGCTAGCTAGTCCTTTCTC GTCGCTGCTCGGCTCGCGGCCCGTGGGGTCGGCCCCGCCACCGTTGCCGCCATGCCCATGAAGGGCCGCTTCCCCATCCGCCGCACCCTG CAATATCTGAGCCAGGGGAACGTGGTGTTCAAGGACTCCGTGAAGGTCATGACAGTGAATTACAACACGCATGGGGAGCTGGGCGAGGGC GCCAGGAAGTTTGTGTTTTTCAACATACCTCAGATTCAATACAAAAACCCTTGGGTGCAGATCATGATGTTTAAGAACATGACGCCGTCA CCCTTCCTGCGATTCTACTTAGGGGGTGTGGGTATGGCTGCCGTGCAGCTGTGCCGTACAGTGGAGAATGTGACAGTGTTCGGAACGGCC TCGGCCAGCAAGCACGAGGCACTGAAGGAGAATGGGGTCACACATCCCATCGACTATCACACGACTGACTACGTGGATGAGATCAAGAAG ATTTCCCCTAAAGGAGTGGACATTGTCATGGACCCTCTGGGTGGGTCAGATACTGCCAAGGGCTACAACCTCCTGAAACCCATGGGCAAA GTCGTCACCTATGGAATGGCCAACCTGCTGACGGGCCCCAAACGGAACCTGATGGCCCTGGCCCGGACATGGTGGAATCAGTTCAGCGTG ACAGCTCTGCAGCTGCTGCAGGCCAACCGGGCTGTGTGTGGCTTCCACCTGGGCTACCTGGATGGTGAGGTGGAGCTGGTCAGTGGTGTG GTGGCCCGCCTCCTGGCTCTGTACAACCAGGGCCACATCAAGCCCCACATTGACTCAGTCTGGCCCTTCGAGAAGGTGGCTGATGCCATG AAACAGATGCAGGAGAAGAAGAATGTGGGCAAGGTCCTCCTGGTTCCAGGGCCAGAGAAGGAGAACTAGGGCAAGTGGCTGTGAGACCCT AGAGACCAGCGAAGGGAGAAGTTGGGAAGCTACGTTCTGTTGGCCACCAGACTTGCATTTCAGCCTCTGTCATAATGCTCTGCCCTCCCT >In-frame_ENST00000253686_ENST00000420567_DA642154_MRPS25_chr3_15100875_-_VAT1_chr17_41170225_length(amino acids)=275AA_start in transcript=141_stop in transcript=968 MPMKGRFPIRRTLQYLSQGNVVFKDSVKVMTVNYNTHGELGEGARKFVFFNIPQIQYKNPWVQIMMFKNMTPSPFLRFYLGGVGMAAVQL CRTVENVTVFGTASASKHEALKENGVTHPIDYHTTDYVDEIKKISPKGVDIVMDPLGGSDTAKGYNLLKPMGKVVTYGMANLLTGPKRNL MALARTWWNQFSVTALQLLQANRAVCGFHLGYLDGEVELVSGVVARLLALYNQGHIKPHIDSVWPFEKVADAMKQMQEKKNVGKVLLVPG -------------------------------------------------------------- >In-frame_ENST00000449354_ENST00000355653_DA642154_MRPS25_chr3_15100875_-_VAT1_chr17_41170225_length(transcript)=2350nt_BP=307nt AGCTAGTCCTTTCTCGTCGCTGCTCGGCTCGCGGCCCGTGGGGTCGGCCCCGCCACCGTTGCCGCCATGCCCATGAAGGGCCGCTTCCCC ATCCGCCGCACCCTGCAATATCTGAGCCAGGGGAACGTGGTGTTCAAGGACTCCGTGAAGGTCATGACAGTGAATTACAACACGCATGGG GAGCTGGGCGAGGGCGCCAGGAAGTTTGTGTTTTTCAACATACCTCAGATTCAATACAAAAACCCTTGGGTGCAGATCATGATGTTTAAG AACATGACGCCGTCACCCTTCCTGCGATTCTACTTAGGGGGTGTGGGTATGGCTGCCGTGCAGCTGTGCCGTACAGTGGAGAATGTGACA GTGTTCGGAACGGCCTCGGCCAGCAAGCACGAGGCACTGAAGGAGAATGGGGTCACACATCCCATCGACTATCACACGACTGACTACGTG GATGAGATCAAGAAGATTTCCCCTAAAGGAGTGGACATTGTCATGGACCCTCTGGGTGGGTCAGATACTGCCAAGGGCTACAACCTCCTG AAACCCATGGGCAAAGTCGTCACCTATGGAATGGCCAACCTGCTGACGGGCCCCAAACGGAACCTGATGGCCCTGGCCCGGACATGGTGG AATCAGTTCAGCGTGACAGCTCTGCAGCTGCTGCAGGCCAACCGGGCTGTGTGTGGCTTCCACCTGGGCTACCTGGATGGTGAGGTGGAG CTGGTCAGTGGTGTGGTGGCCCGCCTCCTGGCTCTGTACAACCAGGGCCACATCAAGCCCCACATTGACTCAGTCTGGCCCTTCGAGAAG GTGGCTGATGCCATGAAACAGATGCAGGAGAAGAAGAATGTGGGCAAGGTCCTCCTGGTTCCAGGGCCAGAGAAGGAGAACTAGGGCAAG TGGCTGTGAGACCCTAGAGACCAGCGAAGGGAGAAGTTGGGAAGCTACGTTCTGTTGGCCACCAGACTTGCATTTCAGCCTCTGTCATAA TGCTCTGCCCTCCCTCCCCCGAAGGTCTCTGTGGTGATGACCGCTCTCCCCTGCCCCTCCCCGCTTCCTGACCTCTGAAGAGGTTGGGAA GTGACCATTTGGATGTCTGGGCCCTGCCAAGGCGACAGGGAGGGTCAGAGGGAGGCCGGCTGCTTCCTGCCCCCACCCTTTCCCCGGGCC TGCTGTGCTGCTTTTGTGCCAAGGTTAGCCAGTCCCCCCTGTTGTGTTCCATGTGCTTTCACCTCTGCCTCATCTTTCCTCCCGTCCCTG CCCCGCCACCTCCCCAAAGAATTGAAACGTCAGCTCAGGATATGGGGCCAATCTCTGTGAGTCCAGCATGTACCTGTCTCTCCCTAGTGT CCCTTCAGCCTGGGCTGACCAGTGCCCGCCTCTGGGCTTGACCAGTTCCCAATCTCGTCCTCTGTCCCCAACTTCTTAAGCACAATTGGG CTTCTTCCATCTCCAGGTTTTCTGCCATTCTTAACCAAGGCTGCCTCTTCCAACAGGGCGGGAATCAGACCTACTCCCCTAGGTCACAAC TCTGGGAAGGATACAGAGCCCCCACCCTTCACTGAGTTCTCTGGATTTGTTCTCAGTGCCTTAGCAACGAAAACCTGTGCTTGTGTGTGT GTGGCGGCGGGGAGGGAGGATCCTGTTTCCCACCTCCTTCTCCTCCCCTGTACTCCCCAGTGCCTTCCTTGTTCTGGTGGAGCTGGGGTT TCTCTCCTCCCCAGTCCCACAACACTGCCAAAAATCTGTGTATGTGCCATTGGGTGGGGCAGCCCCAAGCCTCCTGGGGAGGCAGGGCAA AAACAGGTGCCCTCATCGTGGTCTGTGCCATGTCCCGTCTCTATGGTGGTTGAGGAGAAAGGCGGGGAAGCTTCCTCAGCCTTGCAGATA TGTGTGGCATTTACTAGCCAGAGCTCTGAAAGGCAGTGCTGTCTGTTTCTTGTACTGGGACCAAAGTAAAAATCCAAGCACATTCCCCTT GCAGTTAGGGGAGGCCCTACTGCCTTCTCAAAGCAGAGAGGCAGCTTATCAAACTCAGCCCAAAACTCTGTTTACATGGGTGGGGAGATG GAGCAGGGAAGTACAGAGTGGGATGGTCAGGACCTGGGCCATTGCAACCAAAATGGGGACTTCCTGGGTAGGGAGGTCACTCCCTCTACT CACTGAGCTAGGATTAGGGAGGGTTATTGCCCCAACCATTGCAATGGGAGGTGGAGGGACAGGCTCAGCCTCCTCATTGTCTAAATGAGG CCTAAATGTGTGAAGTGCGATTTCTGCTTTTGTGTACCCCACCACCCCATTACCACAGCTGCCTTTGTGTGTTTGTGTCAATAAAAAGCC >In-frame_ENST00000449354_ENST00000355653_DA642154_MRPS25_chr3_15100875_-_VAT1_chr17_41170225_length(amino acids)=275AA_start in transcript=66_stop in transcript=893 MPMKGRFPIRRTLQYLSQGNVVFKDSVKVMTVNYNTHGELGEGARKFVFFNIPQIQYKNPWVQIMMFKNMTPSPFLRFYLGGVGMAAVQL CRTVENVTVFGTASASKHEALKENGVTHPIDYHTTDYVDEIKKISPKGVDIVMDPLGGSDTAKGYNLLKPMGKVVTYGMANLLTGPKRNL MALARTWWNQFSVTALQLLQANRAVCGFHLGYLDGEVELVSGVVARLLALYNQGHIKPHIDSVWPFEKVADAMKQMQEKKNVGKVLLVPG -------------------------------------------------------------- >In-frame_ENST00000449354_ENST00000587173_DA642154_MRPS25_chr3_15100875_-_VAT1_chr17_41170225_length(transcript)=1056nt_BP=307nt AGCTAGTCCTTTCTCGTCGCTGCTCGGCTCGCGGCCCGTGGGGTCGGCCCCGCCACCGTTGCCGCCATGCCCATGAAGGGCCGCTTCCCC ATCCGCCGCACCCTGCAATATCTGAGCCAGGGGAACGTGGTGTTCAAGGACTCCGTGAAGGTCATGACAGTGAATTACAACACGCATGGG GAGCTGGGCGAGGGCGCCAGGAAGTTTGTGTTTTTCAACATACCTCAGATTCAATACAAAAACCCTTGGGTGCAGATCATGATGTTTAAG AACATGACGCCGTCACCCTTCCTGCGATTCTACTTAGGGGGTGTGGGTATGGCTGCCGTGCAGCTGTGCCGTACAGTGGAGAATGTGACA GTGTTCGGAACGGCCTCGGCCAGCAAGCACGAGGCACTGAAGGAGAATGGGGTCACACATCCCATCGACTATCACACGACTGACTACGTG GATGAGATCAAGAAGATTTCCCCTAAAGGAGTGGACATTGTCATGGACCCTCTGGGTGGGTCAGATACTGCCAAGGGCTACAACCTCCTG AAACCCATGGGCAAAGTCGTCACCTATGGAATGGCCAACCTGCTGACGGGCCCCAAACGGAACCTGATGGCCCTGGCCCGGACATGGTGG AATCAGTTCAGCGTGACAGCTCTGCAGCTGCTGCAGGCCAACCGGGCTGTGTGTGGCTTCCACCTGGGCTACCTGGATGGTGAGGTGGAG CTGGTCAGTGGTGTGGTGGCCCGCCTCCTGGCTCTGTACAACCAGGGCCACATCAAGCCCCACATTGACTCAGTCTGGCCCTTCGAGAAG GTGGCTGATGCCATGAAACAGATGCAGGAGAAGAAGAATGTGGGCAAGGTCCTCCTGGTTCCAGGGCCAGAGAAGGAGAACTAGGGCAAG TGGCTGTGAGACCCTAGAGACCAGCGAAGGGAGAAGTTGGGAAGCTACGTTCTGTTGGCCACCAGACTTGCATTTCAGCCTCTGTCATAA >In-frame_ENST00000449354_ENST00000587173_DA642154_MRPS25_chr3_15100875_-_VAT1_chr17_41170225_length(amino acids)=275AA_start in transcript=66_stop in transcript=893 MPMKGRFPIRRTLQYLSQGNVVFKDSVKVMTVNYNTHGELGEGARKFVFFNIPQIQYKNPWVQIMMFKNMTPSPFLRFYLGGVGMAAVQL CRTVENVTVFGTASASKHEALKENGVTHPIDYHTTDYVDEIKKISPKGVDIVMDPLGGSDTAKGYNLLKPMGKVVTYGMANLLTGPKRNL MALARTWWNQFSVTALQLLQANRAVCGFHLGYLDGEVELVSGVVARLLALYNQGHIKPHIDSVWPFEKVADAMKQMQEKKNVGKVLLVPG -------------------------------------------------------------- >In-frame_ENST00000449354_ENST00000420567_DA642154_MRPS25_chr3_15100875_-_VAT1_chr17_41170225_length(transcript)=1037nt_BP=307nt AGCTAGTCCTTTCTCGTCGCTGCTCGGCTCGCGGCCCGTGGGGTCGGCCCCGCCACCGTTGCCGCCATGCCCATGAAGGGCCGCTTCCCC ATCCGCCGCACCCTGCAATATCTGAGCCAGGGGAACGTGGTGTTCAAGGACTCCGTGAAGGTCATGACAGTGAATTACAACACGCATGGG GAGCTGGGCGAGGGCGCCAGGAAGTTTGTGTTTTTCAACATACCTCAGATTCAATACAAAAACCCTTGGGTGCAGATCATGATGTTTAAG AACATGACGCCGTCACCCTTCCTGCGATTCTACTTAGGGGGTGTGGGTATGGCTGCCGTGCAGCTGTGCCGTACAGTGGAGAATGTGACA GTGTTCGGAACGGCCTCGGCCAGCAAGCACGAGGCACTGAAGGAGAATGGGGTCACACATCCCATCGACTATCACACGACTGACTACGTG GATGAGATCAAGAAGATTTCCCCTAAAGGAGTGGACATTGTCATGGACCCTCTGGGTGGGTCAGATACTGCCAAGGGCTACAACCTCCTG AAACCCATGGGCAAAGTCGTCACCTATGGAATGGCCAACCTGCTGACGGGCCCCAAACGGAACCTGATGGCCCTGGCCCGGACATGGTGG AATCAGTTCAGCGTGACAGCTCTGCAGCTGCTGCAGGCCAACCGGGCTGTGTGTGGCTTCCACCTGGGCTACCTGGATGGTGAGGTGGAG CTGGTCAGTGGTGTGGTGGCCCGCCTCCTGGCTCTGTACAACCAGGGCCACATCAAGCCCCACATTGACTCAGTCTGGCCCTTCGAGAAG GTGGCTGATGCCATGAAACAGATGCAGGAGAAGAAGAATGTGGGCAAGGTCCTCCTGGTTCCAGGGCCAGAGAAGGAGAACTAGGGCAAG TGGCTGTGAGACCCTAGAGACCAGCGAAGGGAGAAGTTGGGAAGCTACGTTCTGTTGGCCACCAGACTTGCATTTCAGCCTCTGTCATAA >In-frame_ENST00000449354_ENST00000420567_DA642154_MRPS25_chr3_15100875_-_VAT1_chr17_41170225_length(amino acids)=275AA_start in transcript=66_stop in transcript=893 MPMKGRFPIRRTLQYLSQGNVVFKDSVKVMTVNYNTHGELGEGARKFVFFNIPQIQYKNPWVQIMMFKNMTPSPFLRFYLGGVGMAAVQL CRTVENVTVFGTASASKHEALKENGVTHPIDYHTTDYVDEIKKISPKGVDIVMDPLGGSDTAKGYNLLKPMGKVVTYGMANLLTGPKRNL MALARTWWNQFSVTALQLLQANRAVCGFHLGYLDGEVELVSGVVARLLALYNQGHIKPHIDSVWPFEKVADAMKQMQEKKNVGKVLLVPG -------------------------------------------------------------- >In-frame_ENST00000444840_ENST00000355653_DA642154_MRPS25_chr3_15100875_-_VAT1_chr17_41170225_length(transcript)=2407nt_BP=364nt GCGCGGGAAGTGGAACCTGGCTCTGGGGAGAAGCCGCGTGAGATCCGCGCGGGTGCTAGCTAGTCCTTTCTCGTCGCTGCTCGGCTCGCG GCCCGTGGGGTCGGCCCCGCCACCGTTGCCGCCATGCCCATGAAGGGCCGCTTCCCCATCCGCCGCACCCTGCAATATCTGAGCCAGGGG AACGTGGTGTTCAAGGACTCCGTGAAGGTCATGACAGTGAATTACAACACGCATGGGGAGCTGGGCGAGGGCGCCAGGAAGTTTGTGTTT TTCAACATACCTCAGATTCAATACAAAAACCCTTGGGTGCAGATCATGATGTTTAAGAACATGACGCCGTCACCCTTCCTGCGATTCTAC TTAGGGGGTGTGGGTATGGCTGCCGTGCAGCTGTGCCGTACAGTGGAGAATGTGACAGTGTTCGGAACGGCCTCGGCCAGCAAGCACGAG GCACTGAAGGAGAATGGGGTCACACATCCCATCGACTATCACACGACTGACTACGTGGATGAGATCAAGAAGATTTCCCCTAAAGGAGTG GACATTGTCATGGACCCTCTGGGTGGGTCAGATACTGCCAAGGGCTACAACCTCCTGAAACCCATGGGCAAAGTCGTCACCTATGGAATG GCCAACCTGCTGACGGGCCCCAAACGGAACCTGATGGCCCTGGCCCGGACATGGTGGAATCAGTTCAGCGTGACAGCTCTGCAGCTGCTG CAGGCCAACCGGGCTGTGTGTGGCTTCCACCTGGGCTACCTGGATGGTGAGGTGGAGCTGGTCAGTGGTGTGGTGGCCCGCCTCCTGGCT CTGTACAACCAGGGCCACATCAAGCCCCACATTGACTCAGTCTGGCCCTTCGAGAAGGTGGCTGATGCCATGAAACAGATGCAGGAGAAG AAGAATGTGGGCAAGGTCCTCCTGGTTCCAGGGCCAGAGAAGGAGAACTAGGGCAAGTGGCTGTGAGACCCTAGAGACCAGCGAAGGGAG AAGTTGGGAAGCTACGTTCTGTTGGCCACCAGACTTGCATTTCAGCCTCTGTCATAATGCTCTGCCCTCCCTCCCCCGAAGGTCTCTGTG GTGATGACCGCTCTCCCCTGCCCCTCCCCGCTTCCTGACCTCTGAAGAGGTTGGGAAGTGACCATTTGGATGTCTGGGCCCTGCCAAGGC GACAGGGAGGGTCAGAGGGAGGCCGGCTGCTTCCTGCCCCCACCCTTTCCCCGGGCCTGCTGTGCTGCTTTTGTGCCAAGGTTAGCCAGT CCCCCCTGTTGTGTTCCATGTGCTTTCACCTCTGCCTCATCTTTCCTCCCGTCCCTGCCCCGCCACCTCCCCAAAGAATTGAAACGTCAG CTCAGGATATGGGGCCAATCTCTGTGAGTCCAGCATGTACCTGTCTCTCCCTAGTGTCCCTTCAGCCTGGGCTGACCAGTGCCCGCCTCT GGGCTTGACCAGTTCCCAATCTCGTCCTCTGTCCCCAACTTCTTAAGCACAATTGGGCTTCTTCCATCTCCAGGTTTTCTGCCATTCTTA ACCAAGGCTGCCTCTTCCAACAGGGCGGGAATCAGACCTACTCCCCTAGGTCACAACTCTGGGAAGGATACAGAGCCCCCACCCTTCACT GAGTTCTCTGGATTTGTTCTCAGTGCCTTAGCAACGAAAACCTGTGCTTGTGTGTGTGTGGCGGCGGGGAGGGAGGATCCTGTTTCCCAC CTCCTTCTCCTCCCCTGTACTCCCCAGTGCCTTCCTTGTTCTGGTGGAGCTGGGGTTTCTCTCCTCCCCAGTCCCACAACACTGCCAAAA ATCTGTGTATGTGCCATTGGGTGGGGCAGCCCCAAGCCTCCTGGGGAGGCAGGGCAAAAACAGGTGCCCTCATCGTGGTCTGTGCCATGT CCCGTCTCTATGGTGGTTGAGGAGAAAGGCGGGGAAGCTTCCTCAGCCTTGCAGATATGTGTGGCATTTACTAGCCAGAGCTCTGAAAGG CAGTGCTGTCTGTTTCTTGTACTGGGACCAAAGTAAAAATCCAAGCACATTCCCCTTGCAGTTAGGGGAGGCCCTACTGCCTTCTCAAAG CAGAGAGGCAGCTTATCAAACTCAGCCCAAAACTCTGTTTACATGGGTGGGGAGATGGAGCAGGGAAGTACAGAGTGGGATGGTCAGGAC CTGGGCCATTGCAACCAAAATGGGGACTTCCTGGGTAGGGAGGTCACTCCCTCTACTCACTGAGCTAGGATTAGGGAGGGTTATTGCCCC AACCATTGCAATGGGAGGTGGAGGGACAGGCTCAGCCTCCTCATTGTCTAAATGAGGCCTAAATGTGTGAAGTGCGATTTCTGCTTTTGT >In-frame_ENST00000444840_ENST00000355653_DA642154_MRPS25_chr3_15100875_-_VAT1_chr17_41170225_length(amino acids)=275AA_start in transcript=123_stop in transcript=950 MPMKGRFPIRRTLQYLSQGNVVFKDSVKVMTVNYNTHGELGEGARKFVFFNIPQIQYKNPWVQIMMFKNMTPSPFLRFYLGGVGMAAVQL CRTVENVTVFGTASASKHEALKENGVTHPIDYHTTDYVDEIKKISPKGVDIVMDPLGGSDTAKGYNLLKPMGKVVTYGMANLLTGPKRNL MALARTWWNQFSVTALQLLQANRAVCGFHLGYLDGEVELVSGVVARLLALYNQGHIKPHIDSVWPFEKVADAMKQMQEKKNVGKVLLVPG -------------------------------------------------------------- >In-frame_ENST00000444840_ENST00000587173_DA642154_MRPS25_chr3_15100875_-_VAT1_chr17_41170225_length(transcript)=1113nt_BP=364nt GCGCGGGAAGTGGAACCTGGCTCTGGGGAGAAGCCGCGTGAGATCCGCGCGGGTGCTAGCTAGTCCTTTCTCGTCGCTGCTCGGCTCGCG GCCCGTGGGGTCGGCCCCGCCACCGTTGCCGCCATGCCCATGAAGGGCCGCTTCCCCATCCGCCGCACCCTGCAATATCTGAGCCAGGGG AACGTGGTGTTCAAGGACTCCGTGAAGGTCATGACAGTGAATTACAACACGCATGGGGAGCTGGGCGAGGGCGCCAGGAAGTTTGTGTTT TTCAACATACCTCAGATTCAATACAAAAACCCTTGGGTGCAGATCATGATGTTTAAGAACATGACGCCGTCACCCTTCCTGCGATTCTAC TTAGGGGGTGTGGGTATGGCTGCCGTGCAGCTGTGCCGTACAGTGGAGAATGTGACAGTGTTCGGAACGGCCTCGGCCAGCAAGCACGAG GCACTGAAGGAGAATGGGGTCACACATCCCATCGACTATCACACGACTGACTACGTGGATGAGATCAAGAAGATTTCCCCTAAAGGAGTG GACATTGTCATGGACCCTCTGGGTGGGTCAGATACTGCCAAGGGCTACAACCTCCTGAAACCCATGGGCAAAGTCGTCACCTATGGAATG GCCAACCTGCTGACGGGCCCCAAACGGAACCTGATGGCCCTGGCCCGGACATGGTGGAATCAGTTCAGCGTGACAGCTCTGCAGCTGCTG CAGGCCAACCGGGCTGTGTGTGGCTTCCACCTGGGCTACCTGGATGGTGAGGTGGAGCTGGTCAGTGGTGTGGTGGCCCGCCTCCTGGCT CTGTACAACCAGGGCCACATCAAGCCCCACATTGACTCAGTCTGGCCCTTCGAGAAGGTGGCTGATGCCATGAAACAGATGCAGGAGAAG AAGAATGTGGGCAAGGTCCTCCTGGTTCCAGGGCCAGAGAAGGAGAACTAGGGCAAGTGGCTGTGAGACCCTAGAGACCAGCGAAGGGAG AAGTTGGGAAGCTACGTTCTGTTGGCCACCAGACTTGCATTTCAGCCTCTGTCATAATGCTCTGCCCTCCCTCCCCCGAAGGTCTCTGTG >In-frame_ENST00000444840_ENST00000587173_DA642154_MRPS25_chr3_15100875_-_VAT1_chr17_41170225_length(amino acids)=275AA_start in transcript=123_stop in transcript=950 MPMKGRFPIRRTLQYLSQGNVVFKDSVKVMTVNYNTHGELGEGARKFVFFNIPQIQYKNPWVQIMMFKNMTPSPFLRFYLGGVGMAAVQL CRTVENVTVFGTASASKHEALKENGVTHPIDYHTTDYVDEIKKISPKGVDIVMDPLGGSDTAKGYNLLKPMGKVVTYGMANLLTGPKRNL MALARTWWNQFSVTALQLLQANRAVCGFHLGYLDGEVELVSGVVARLLALYNQGHIKPHIDSVWPFEKVADAMKQMQEKKNVGKVLLVPG -------------------------------------------------------------- >In-frame_ENST00000444840_ENST00000420567_DA642154_MRPS25_chr3_15100875_-_VAT1_chr17_41170225_length(transcript)=1094nt_BP=364nt GCGCGGGAAGTGGAACCTGGCTCTGGGGAGAAGCCGCGTGAGATCCGCGCGGGTGCTAGCTAGTCCTTTCTCGTCGCTGCTCGGCTCGCG GCCCGTGGGGTCGGCCCCGCCACCGTTGCCGCCATGCCCATGAAGGGCCGCTTCCCCATCCGCCGCACCCTGCAATATCTGAGCCAGGGG AACGTGGTGTTCAAGGACTCCGTGAAGGTCATGACAGTGAATTACAACACGCATGGGGAGCTGGGCGAGGGCGCCAGGAAGTTTGTGTTT TTCAACATACCTCAGATTCAATACAAAAACCCTTGGGTGCAGATCATGATGTTTAAGAACATGACGCCGTCACCCTTCCTGCGATTCTAC TTAGGGGGTGTGGGTATGGCTGCCGTGCAGCTGTGCCGTACAGTGGAGAATGTGACAGTGTTCGGAACGGCCTCGGCCAGCAAGCACGAG GCACTGAAGGAGAATGGGGTCACACATCCCATCGACTATCACACGACTGACTACGTGGATGAGATCAAGAAGATTTCCCCTAAAGGAGTG GACATTGTCATGGACCCTCTGGGTGGGTCAGATACTGCCAAGGGCTACAACCTCCTGAAACCCATGGGCAAAGTCGTCACCTATGGAATG GCCAACCTGCTGACGGGCCCCAAACGGAACCTGATGGCCCTGGCCCGGACATGGTGGAATCAGTTCAGCGTGACAGCTCTGCAGCTGCTG CAGGCCAACCGGGCTGTGTGTGGCTTCCACCTGGGCTACCTGGATGGTGAGGTGGAGCTGGTCAGTGGTGTGGTGGCCCGCCTCCTGGCT CTGTACAACCAGGGCCACATCAAGCCCCACATTGACTCAGTCTGGCCCTTCGAGAAGGTGGCTGATGCCATGAAACAGATGCAGGAGAAG AAGAATGTGGGCAAGGTCCTCCTGGTTCCAGGGCCAGAGAAGGAGAACTAGGGCAAGTGGCTGTGAGACCCTAGAGACCAGCGAAGGGAG AAGTTGGGAAGCTACGTTCTGTTGGCCACCAGACTTGCATTTCAGCCTCTGTCATAATGCTCTGCCCTCCCTCCCCCGAAGGTCTCTGTG >In-frame_ENST00000444840_ENST00000420567_DA642154_MRPS25_chr3_15100875_-_VAT1_chr17_41170225_length(amino acids)=275AA_start in transcript=123_stop in transcript=950 MPMKGRFPIRRTLQYLSQGNVVFKDSVKVMTVNYNTHGELGEGARKFVFFNIPQIQYKNPWVQIMMFKNMTPSPFLRFYLGGVGMAAVQL CRTVENVTVFGTASASKHEALKENGVTHPIDYHTTDYVDEIKKISPKGVDIVMDPLGGSDTAKGYNLLKPMGKVVTYGMANLLTGPKRNL MALARTWWNQFSVTALQLLQANRAVCGFHLGYLDGEVELVSGVVARLLALYNQGHIKPHIDSVWPFEKVADAMKQMQEKKNVGKVLLVPG -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for MRPS25-VAT1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for MRPS25-VAT1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for MRPS25-VAT1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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