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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:MSI2-PCTP (FusionGDB2 ID:54996)

Fusion Gene Summary for MSI2-PCTP

check button Fusion gene summary
Fusion gene informationFusion gene name: MSI2-PCTP
Fusion gene ID: 54996
HgeneTgene
Gene symbol

MSI2

PCTP

Gene ID

124540

58488

Gene namemusashi RNA binding protein 2phosphatidylcholine transfer protein
SynonymsMSI2HPC-TP|STARD2
Cytomap

17q22

17q22

Type of geneprotein-codingprotein-coding
DescriptionRNA-binding protein Musashi homolog 2musashi homolog 2musashi-2phosphatidylcholine transfer proteinSTART domain-containing protein 2StAR-related lipid transfer (START) domain containing 2stAR-related lipid transfer protein 2
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000416426, ENST00000284073, 
ENST00000322684, ENST00000442934, 
ENST00000579180, ENST00000579505, 
ENST00000573500, ENST00000576221, 
ENST00000268896, ENST00000576183, 
ENST00000325214, 
Fusion gene scores* DoF score40 X 16 X 16=102409 X 7 X 5=315
# samples 4514
** MAII scorelog2(45/10240*10)=-4.50814690367033
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(14/315*10)=-1.16992500144231
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: MSI2 [Title/Abstract] AND PCTP [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointMSI2(55339553)-PCTP(53844696), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgenePCTP

GO:0015914

phospholipid transport

12055623


check buttonFusion gene breakpoints across MSI2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across PCTP (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-D8-A27F-01AMSI2chr17

55339553

+PCTPchr17

53844696

+
ChimerDB4BRCATCGA-D8-A27FMSI2chr17

55339553

+PCTPchr17

53844695

+
ChimerDB4BRCATCGA-D8-A27F-01AMSI2chr17

55339553

-PCTPchr17

53844696

+
ChimerDB4BRCATCGA-D8-A27F-01AMSI2chr17

55339552

+PCTPchr17

53844695

+


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Fusion Gene ORF analysis for MSI2-PCTP

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000416426ENST00000573500MSI2chr17

55339553

+PCTPchr17

53844696

+
5CDS-intronENST00000416426ENST00000576221MSI2chr17

55339553

+PCTPchr17

53844696

+
5CDS-intronENST00000416426ENST00000268896MSI2chr17

55339553

+PCTPchr17

53844696

+
5CDS-intronENST00000416426ENST00000576183MSI2chr17

55339553

+PCTPchr17

53844696

+
5CDS-5UTRENST00000416426ENST00000325214MSI2chr17

55339553

+PCTPchr17

53844696

+
In-frameENST00000284073ENST00000573500MSI2chr17

55339553

+PCTPchr17

53844696

+
5CDS-intronENST00000284073ENST00000576221MSI2chr17

55339553

+PCTPchr17

53844696

+
5CDS-intronENST00000284073ENST00000268896MSI2chr17

55339553

+PCTPchr17

53844696

+
5CDS-intronENST00000284073ENST00000576183MSI2chr17

55339553

+PCTPchr17

53844696

+
5CDS-5UTRENST00000284073ENST00000325214MSI2chr17

55339553

+PCTPchr17

53844696

+
In-frameENST00000322684ENST00000573500MSI2chr17

55339553

+PCTPchr17

53844696

+
5CDS-intronENST00000322684ENST00000576221MSI2chr17

55339553

+PCTPchr17

53844696

+
5CDS-intronENST00000322684ENST00000268896MSI2chr17

55339553

+PCTPchr17

53844696

+
5CDS-intronENST00000322684ENST00000576183MSI2chr17

55339553

+PCTPchr17

53844696

+
5CDS-5UTRENST00000322684ENST00000325214MSI2chr17

55339553

+PCTPchr17

53844696

+
intron-3CDSENST00000442934ENST00000573500MSI2chr17

55339553

+PCTPchr17

53844696

+
intron-intronENST00000442934ENST00000576221MSI2chr17

55339553

+PCTPchr17

53844696

+
intron-intronENST00000442934ENST00000268896MSI2chr17

55339553

+PCTPchr17

53844696

+
intron-intronENST00000442934ENST00000576183MSI2chr17

55339553

+PCTPchr17

53844696

+
intron-5UTRENST00000442934ENST00000325214MSI2chr17

55339553

+PCTPchr17

53844696

+
intron-3CDSENST00000579180ENST00000573500MSI2chr17

55339553

+PCTPchr17

53844696

+
intron-intronENST00000579180ENST00000576221MSI2chr17

55339553

+PCTPchr17

53844696

+
intron-intronENST00000579180ENST00000268896MSI2chr17

55339553

+PCTPchr17

53844696

+
intron-intronENST00000579180ENST00000576183MSI2chr17

55339553

+PCTPchr17

53844696

+
intron-5UTRENST00000579180ENST00000325214MSI2chr17

55339553

+PCTPchr17

53844696

+
intron-3CDSENST00000579505ENST00000573500MSI2chr17

55339553

+PCTPchr17

53844696

+
intron-intronENST00000579505ENST00000576221MSI2chr17

55339553

+PCTPchr17

53844696

+
intron-intronENST00000579505ENST00000268896MSI2chr17

55339553

+PCTPchr17

53844696

+
intron-intronENST00000579505ENST00000576183MSI2chr17

55339553

+PCTPchr17

53844696

+
intron-5UTRENST00000579505ENST00000325214MSI2chr17

55339553

+PCTPchr17

53844696

+
In-frameENST00000416426ENST00000573500MSI2chr17

55339553

+PCTPchr17

53844695

+
5CDS-intronENST00000416426ENST00000576221MSI2chr17

55339553

+PCTPchr17

53844695

+
5CDS-intronENST00000416426ENST00000268896MSI2chr17

55339553

+PCTPchr17

53844695

+
5CDS-intronENST00000416426ENST00000576183MSI2chr17

55339553

+PCTPchr17

53844695

+
5CDS-5UTRENST00000416426ENST00000325214MSI2chr17

55339553

+PCTPchr17

53844695

+
In-frameENST00000284073ENST00000573500MSI2chr17

55339553

+PCTPchr17

53844695

+
5CDS-intronENST00000284073ENST00000576221MSI2chr17

55339553

+PCTPchr17

53844695

+
5CDS-intronENST00000284073ENST00000268896MSI2chr17

55339553

+PCTPchr17

53844695

+
5CDS-intronENST00000284073ENST00000576183MSI2chr17

55339553

+PCTPchr17

53844695

+
5CDS-5UTRENST00000284073ENST00000325214MSI2chr17

55339553

+PCTPchr17

53844695

+
In-frameENST00000322684ENST00000573500MSI2chr17

55339553

+PCTPchr17

53844695

+
5CDS-intronENST00000322684ENST00000576221MSI2chr17

55339553

+PCTPchr17

53844695

+
5CDS-intronENST00000322684ENST00000268896MSI2chr17

55339553

+PCTPchr17

53844695

+
5CDS-intronENST00000322684ENST00000576183MSI2chr17

55339553

+PCTPchr17

53844695

+
5CDS-5UTRENST00000322684ENST00000325214MSI2chr17

55339553

+PCTPchr17

53844695

+
intron-3CDSENST00000442934ENST00000573500MSI2chr17

55339553

+PCTPchr17

53844695

+
intron-intronENST00000442934ENST00000576221MSI2chr17

55339553

+PCTPchr17

53844695

+
intron-intronENST00000442934ENST00000268896MSI2chr17

55339553

+PCTPchr17

53844695

+
intron-intronENST00000442934ENST00000576183MSI2chr17

55339553

+PCTPchr17

53844695

+
intron-5UTRENST00000442934ENST00000325214MSI2chr17

55339553

+PCTPchr17

53844695

+
intron-3CDSENST00000579180ENST00000573500MSI2chr17

55339553

+PCTPchr17

53844695

+
intron-intronENST00000579180ENST00000576221MSI2chr17

55339553

+PCTPchr17

53844695

+
intron-intronENST00000579180ENST00000268896MSI2chr17

55339553

+PCTPchr17

53844695

+
intron-intronENST00000579180ENST00000576183MSI2chr17

55339553

+PCTPchr17

53844695

+
intron-5UTRENST00000579180ENST00000325214MSI2chr17

55339553

+PCTPchr17

53844695

+
intron-3CDSENST00000579505ENST00000573500MSI2chr17

55339553

+PCTPchr17

53844695

+
intron-intronENST00000579505ENST00000576221MSI2chr17

55339553

+PCTPchr17

53844695

+
intron-intronENST00000579505ENST00000268896MSI2chr17

55339553

+PCTPchr17

53844695

+
intron-intronENST00000579505ENST00000576183MSI2chr17

55339553

+PCTPchr17

53844695

+
intron-5UTRENST00000579505ENST00000325214MSI2chr17

55339553

+PCTPchr17

53844695

+
In-frameENST00000416426ENST00000573500MSI2chr17

55339552

+PCTPchr17

53844695

+
5CDS-intronENST00000416426ENST00000576221MSI2chr17

55339552

+PCTPchr17

53844695

+
5CDS-intronENST00000416426ENST00000268896MSI2chr17

55339552

+PCTPchr17

53844695

+
5CDS-intronENST00000416426ENST00000576183MSI2chr17

55339552

+PCTPchr17

53844695

+
5CDS-5UTRENST00000416426ENST00000325214MSI2chr17

55339552

+PCTPchr17

53844695

+
In-frameENST00000284073ENST00000573500MSI2chr17

55339552

+PCTPchr17

53844695

+
5CDS-intronENST00000284073ENST00000576221MSI2chr17

55339552

+PCTPchr17

53844695

+
5CDS-intronENST00000284073ENST00000268896MSI2chr17

55339552

+PCTPchr17

53844695

+
5CDS-intronENST00000284073ENST00000576183MSI2chr17

55339552

+PCTPchr17

53844695

+
5CDS-5UTRENST00000284073ENST00000325214MSI2chr17

55339552

+PCTPchr17

53844695

+
In-frameENST00000322684ENST00000573500MSI2chr17

55339552

+PCTPchr17

53844695

+
5CDS-intronENST00000322684ENST00000576221MSI2chr17

55339552

+PCTPchr17

53844695

+
5CDS-intronENST00000322684ENST00000268896MSI2chr17

55339552

+PCTPchr17

53844695

+
5CDS-intronENST00000322684ENST00000576183MSI2chr17

55339552

+PCTPchr17

53844695

+
5CDS-5UTRENST00000322684ENST00000325214MSI2chr17

55339552

+PCTPchr17

53844695

+
intron-3CDSENST00000442934ENST00000573500MSI2chr17

55339552

+PCTPchr17

53844695

+
intron-intronENST00000442934ENST00000576221MSI2chr17

55339552

+PCTPchr17

53844695

+
intron-intronENST00000442934ENST00000268896MSI2chr17

55339552

+PCTPchr17

53844695

+
intron-intronENST00000442934ENST00000576183MSI2chr17

55339552

+PCTPchr17

53844695

+
intron-5UTRENST00000442934ENST00000325214MSI2chr17

55339552

+PCTPchr17

53844695

+
intron-3CDSENST00000579180ENST00000573500MSI2chr17

55339552

+PCTPchr17

53844695

+
intron-intronENST00000579180ENST00000576221MSI2chr17

55339552

+PCTPchr17

53844695

+
intron-intronENST00000579180ENST00000268896MSI2chr17

55339552

+PCTPchr17

53844695

+
intron-intronENST00000579180ENST00000576183MSI2chr17

55339552

+PCTPchr17

53844695

+
intron-5UTRENST00000579180ENST00000325214MSI2chr17

55339552

+PCTPchr17

53844695

+
intron-3CDSENST00000579505ENST00000573500MSI2chr17

55339552

+PCTPchr17

53844695

+
intron-intronENST00000579505ENST00000576221MSI2chr17

55339552

+PCTPchr17

53844695

+
intron-intronENST00000579505ENST00000268896MSI2chr17

55339552

+PCTPchr17

53844695

+
intron-intronENST00000579505ENST00000576183MSI2chr17

55339552

+PCTPchr17

53844695

+
intron-5UTRENST00000579505ENST00000325214MSI2chr17

55339552

+PCTPchr17

53844695

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000416426MSI2chr1755339553+ENST00000573500PCTPchr1753844696+114938193899268
ENST00000284073MSI2chr1755339553+ENST00000573500PCTPchr1753844696+12895211791039286
ENST00000322684MSI2chr1755339553+ENST00000573500PCTPchr1753844696+110333535853272
ENST00000416426MSI2chr1755339553+ENST00000573500PCTPchr1753844695+114938193899268
ENST00000284073MSI2chr1755339553+ENST00000573500PCTPchr1753844695+12895211791039286
ENST00000322684MSI2chr1755339553+ENST00000573500PCTPchr1753844695+110333535853272
ENST00000416426MSI2chr1755339552+ENST00000573500PCTPchr1753844695+114938193899268
ENST00000284073MSI2chr1755339552+ENST00000573500PCTPchr1753844695+12895211791039286
ENST00000322684MSI2chr1755339552+ENST00000573500PCTPchr1753844695+110333535853272

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000416426ENST00000573500MSI2chr1755339553+PCTPchr1753844696+0.0036356570.9963644
ENST00000284073ENST00000573500MSI2chr1755339553+PCTPchr1753844696+0.0061710480.99382895
ENST00000322684ENST00000573500MSI2chr1755339553+PCTPchr1753844696+0.0024788590.9975211
ENST00000416426ENST00000573500MSI2chr1755339553+PCTPchr1753844695+0.0036356570.9963644
ENST00000284073ENST00000573500MSI2chr1755339553+PCTPchr1753844695+0.0061710480.99382895
ENST00000322684ENST00000573500MSI2chr1755339553+PCTPchr1753844695+0.0024788590.9975211
ENST00000416426ENST00000573500MSI2chr1755339552+PCTPchr1753844695+0.0036356570.9963644
ENST00000284073ENST00000573500MSI2chr1755339552+PCTPchr1753844695+0.0061710480.99382895
ENST00000322684ENST00000573500MSI2chr1755339552+PCTPchr1753844695+0.0024788590.9975211

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Fusion Genomic Features for MSI2-PCTP


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for MSI2-PCTP


check button Go to

FGviewer for the breakpoints of chr17:55339553-chr17:53844696

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgenePCTPchr17:55339552chr17:53844695ENST00000325214061_2120143.0DomainSTART
TgenePCTPchr17:55339553chr17:53844695ENST00000325214061_2120143.0DomainSTART
TgenePCTPchr17:55339553chr17:53844696ENST00000325214061_2120143.0DomainSTART

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneMSI2chr17:55339552chr17:53844695ENST00000284073+514253_260104.01951.0Compositional biasNote=Poly-Ala
HgeneMSI2chr17:55339552chr17:53844695ENST00000322684+410253_260100.0252.0Compositional biasNote=Poly-Ala
HgeneMSI2chr17:55339552chr17:53844695ENST00000579180+17253_2600152.0Compositional biasNote=Poly-Ala
HgeneMSI2chr17:55339553chr17:53844695ENST00000284073+514253_260104.01951.0Compositional biasNote=Poly-Ala
HgeneMSI2chr17:55339553chr17:53844695ENST00000322684+410253_260100.0252.0Compositional biasNote=Poly-Ala
HgeneMSI2chr17:55339553chr17:53844695ENST00000579180+17253_2600152.0Compositional biasNote=Poly-Ala
HgeneMSI2chr17:55339553chr17:53844696ENST00000284073+514253_260104.01951.0Compositional biasNote=Poly-Ala
HgeneMSI2chr17:55339553chr17:53844696ENST00000322684+410253_260100.0252.0Compositional biasNote=Poly-Ala
HgeneMSI2chr17:55339553chr17:53844696ENST00000579180+17253_2600152.0Compositional biasNote=Poly-Ala
HgeneMSI2chr17:55339552chr17:53844695ENST00000284073+514110_187104.01951.0DomainRRM 2
HgeneMSI2chr17:55339552chr17:53844695ENST00000284073+51421_111104.01951.0DomainRRM 1
HgeneMSI2chr17:55339552chr17:53844695ENST00000322684+410110_187100.0252.0DomainRRM 2
HgeneMSI2chr17:55339552chr17:53844695ENST00000322684+41021_111100.0252.0DomainRRM 1
HgeneMSI2chr17:55339552chr17:53844695ENST00000579180+17110_1870152.0DomainRRM 2
HgeneMSI2chr17:55339552chr17:53844695ENST00000579180+1721_1110152.0DomainRRM 1
HgeneMSI2chr17:55339553chr17:53844695ENST00000284073+514110_187104.01951.0DomainRRM 2
HgeneMSI2chr17:55339553chr17:53844695ENST00000284073+51421_111104.01951.0DomainRRM 1
HgeneMSI2chr17:55339553chr17:53844695ENST00000322684+410110_187100.0252.0DomainRRM 2
HgeneMSI2chr17:55339553chr17:53844695ENST00000322684+41021_111100.0252.0DomainRRM 1
HgeneMSI2chr17:55339553chr17:53844695ENST00000579180+17110_1870152.0DomainRRM 2
HgeneMSI2chr17:55339553chr17:53844695ENST00000579180+1721_1110152.0DomainRRM 1
HgeneMSI2chr17:55339553chr17:53844696ENST00000284073+514110_187104.01951.0DomainRRM 2
HgeneMSI2chr17:55339553chr17:53844696ENST00000284073+51421_111104.01951.0DomainRRM 1
HgeneMSI2chr17:55339553chr17:53844696ENST00000322684+410110_187100.0252.0DomainRRM 2
HgeneMSI2chr17:55339553chr17:53844696ENST00000322684+41021_111100.0252.0DomainRRM 1
HgeneMSI2chr17:55339553chr17:53844696ENST00000579180+17110_1870152.0DomainRRM 2
HgeneMSI2chr17:55339553chr17:53844696ENST00000579180+1721_1110152.0DomainRRM 1
TgenePCTPchr17:55339552chr17:53844695ENST00000268896061_21247.0215.0DomainSTART
TgenePCTPchr17:55339553chr17:53844695ENST00000268896061_21247.0215.0DomainSTART
TgenePCTPchr17:55339553chr17:53844696ENST00000268896061_21247.0215.0DomainSTART


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Fusion Gene Sequence for MSI2-PCTP


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000416426_ENST00000573500_TCGA-D8-A27F-01A_MSI2_chr17_55339553_+_PCTP_chr17_53844696_length(transcript)=1149nt_BP=381nt
AGAGCCAGAGAGAACTTCCAGCGCAAAAGGAAAATAAAACTTGTGGCTGGTGTTTGTGCAGGAGGGTCTCCGCCATCCTGAAGCCCCCCG
ATCCTGGGGCGTCTCGGGGGCCGCCAAAGGAGCGCCAGGGTTAAAATGTTTATCGGTGGACTGAGCTGGCAGACCTCACCAGATAGCCTT
AGAGACTATTTTAGCAAATTTGGAGAAATTAGAGAATGTATGGTCATGAGAGATCCCACTACGAAACGCTCCAGAGGCTTCGGTTTCGTC
ACGTTCGCAGACCCAGCAAGTGTAGATAAAGTATTAGGTCAGCCCCACCATGAGTTAGATTCCAAGACGATTGACCCCAAAGTTGCATTT
CCTCGTCGAGCGCAACCCAAGAAGACTGGACTTTATGAGTATAAAGTCTTTGGTGTTCTGGAGGACTGCTCACCAACTCTACTGGCAGAC
ATCTATATGGACTCAGATTACAGAAAACAATGGGACCAGTATGTTAAAGAACTCTATGAACAAGAATGCAACGGAGAGACTGTGGTCTAC
TGGGAAGTGAAGTACCCTTTTCCCATGTCCAACAGAGACTATGTCTACCTTCGGCAGCGGCGAGACCTGGACATGGAAGGGAGGAAGATC
CATGTGATCCTGGCCCGGAGCACCTCCATGCCTCAGCTTGGCGAGAGGTCTGGGGTGATCCGGGTGAAGCAATACAAGCAGAGCCTGGCG
ATCGAGAGTGACGGCAAGAAGGGGAGCAAAGTTTTCATGTATTACTTCGATAACCCGGGTGGCCAAATTCCGTCCTGGCTCATTAACTGG
GCCGCCAAGAATCAGAGCAGAACCAAGCGGGAAGCTCAGAATCAGAGAGACCTCATCAAGTTTTTGGCAAACCCAAACATTCTGCAATAG
ATTGAGTGGAAGGAAGAGGAAGGACATAAAGATAAAGACATGAGAAAAGAAGCTGAGTCTTTGTTGAAACACTGAAATGGGTGCAGGTAT
CATTTCTTATCTCATTGTTTTTTCTCATAAGCCCTGAATTAATTCATTTATTCACAGTATTTTCGCAGATGTGAAATTCACATATTATTC

>In-frame_ENST00000416426_ENST00000573500_TCGA-D8-A27F-01A_MSI2_chr17_55339553_+_PCTP_chr17_53844696_length(amino acids)=268AA_start in transcript=93_stop in transcript=899
MGRLGGRQRSARVKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLGQPHHELDSKTIDPKVAFP
RRAQPKKTGLYEYKVFGVLEDCSPTLLADIYMDSDYRKQWDQYVKELYEQECNGETVVYWEVKYPFPMSNRDYVYLRQRRDLDMEGRKIH

--------------------------------------------------------------
>In-frame_ENST00000284073_ENST00000573500_TCGA-D8-A27F-01A_MSI2_chr17_55339553_+_PCTP_chr17_53844696_length(transcript)=1289nt_BP=521nt
CGGGGCTGAGCTAAGCCGAGCCCACGTGTGACGGCTCTCGCCGCTGCCCCGGCTCCGCCGCTCGCAGAGAGATTCGGAGGAGCCCGGGCG
GGGGGGAGGAGGAGGGGGAGGAGGGAGCGGAGATCTCGGGGCTCGGAGCCGGCCGCCGCTCCGCTCCGATCGCTGTGGGGCTTGGTTTTT
TGGGGGTGGGGGGGCGGGGGGGCTCAGATATGGAGGCAAATGGGAGCCAAGGCACCTCGGGCAGCGCCAACGACTCCCAGCACGACCCCG
GTAAAATGTTTATCGGTGGACTGAGCTGGCAGACCTCACCAGATAGCCTTAGAGACTATTTTAGCAAATTTGGAGAAATTAGAGAATGTA
TGGTCATGAGAGATCCCACTACGAAACGCTCCAGAGGCTTCGGTTTCGTCACGTTCGCAGACCCAGCAAGTGTAGATAAAGTATTAGGTC
AGCCCCACCATGAGTTAGATTCCAAGACGATTGACCCCAAAGTTGCATTTCCTCGTCGAGCGCAACCCAAGAAGACTGGACTTTATGAGT
ATAAAGTCTTTGGTGTTCTGGAGGACTGCTCACCAACTCTACTGGCAGACATCTATATGGACTCAGATTACAGAAAACAATGGGACCAGT
ATGTTAAAGAACTCTATGAACAAGAATGCAACGGAGAGACTGTGGTCTACTGGGAAGTGAAGTACCCTTTTCCCATGTCCAACAGAGACT
ATGTCTACCTTCGGCAGCGGCGAGACCTGGACATGGAAGGGAGGAAGATCCATGTGATCCTGGCCCGGAGCACCTCCATGCCTCAGCTTG
GCGAGAGGTCTGGGGTGATCCGGGTGAAGCAATACAAGCAGAGCCTGGCGATCGAGAGTGACGGCAAGAAGGGGAGCAAAGTTTTCATGT
ATTACTTCGATAACCCGGGTGGCCAAATTCCGTCCTGGCTCATTAACTGGGCCGCCAAGAATCAGAGCAGAACCAAGCGGGAAGCTCAGA
ATCAGAGAGACCTCATCAAGTTTTTGGCAAACCCAAACATTCTGCAATAGATTGAGTGGAAGGAAGAGGAAGGACATAAAGATAAAGACA
TGAGAAAAGAAGCTGAGTCTTTGTTGAAACACTGAAATGGGTGCAGGTATCATTTCTTATCTCATTGTTTTTTCTCATAAGCCCTGAATT
AATTCATTTATTCACAGTATTTTCGCAGATGTGAAATTCACATATTATTCACAGATGTGTTCACTATCATCTATGTACTGGAAAGATAGC

>In-frame_ENST00000284073_ENST00000573500_TCGA-D8-A27F-01A_MSI2_chr17_55339553_+_PCTP_chr17_53844696_length(amino acids)=286AA_start in transcript=179_stop in transcript=1039
MGVGGRGGSDMEANGSQGTSGSANDSQHDPGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLG
QPHHELDSKTIDPKVAFPRRAQPKKTGLYEYKVFGVLEDCSPTLLADIYMDSDYRKQWDQYVKELYEQECNGETVVYWEVKYPFPMSNRD
YVYLRQRRDLDMEGRKIHVILARSTSMPQLGERSGVIRVKQYKQSLAIESDGKKGSKVFMYYFDNPGGQIPSWLINWAAKNQSRTKREAQ

--------------------------------------------------------------
>In-frame_ENST00000322684_ENST00000573500_TCGA-D8-A27F-01A_MSI2_chr17_55339553_+_PCTP_chr17_53844696_length(transcript)=1103nt_BP=335nt
GCTTTCCTTTTAGCTTTTGTAAGTTACACGTCAAAATGGCCGATCTGACATCGGTGCTCACTTCTGTTATGTTTTCTCCCTCTAGTAAAA
TGTTTATCGGTGGACTGAGCTGGCAGACCTCACCAGATAGCCTTAGAGACTATTTTAGCAAATTTGGAGAAATTAGAGAATGTATGGTCA
TGAGAGATCCCACTACGAAACGCTCCAGAGGCTTCGGTTTCGTCACGTTCGCAGACCCAGCAAGTGTAGATAAAGTATTAGGTCAGCCCC
ACCATGAGTTAGATTCCAAGACGATTGACCCCAAAGTTGCATTTCCTCGTCGAGCGCAACCCAAGAAGACTGGACTTTATGAGTATAAAG
TCTTTGGTGTTCTGGAGGACTGCTCACCAACTCTACTGGCAGACATCTATATGGACTCAGATTACAGAAAACAATGGGACCAGTATGTTA
AAGAACTCTATGAACAAGAATGCAACGGAGAGACTGTGGTCTACTGGGAAGTGAAGTACCCTTTTCCCATGTCCAACAGAGACTATGTCT
ACCTTCGGCAGCGGCGAGACCTGGACATGGAAGGGAGGAAGATCCATGTGATCCTGGCCCGGAGCACCTCCATGCCTCAGCTTGGCGAGA
GGTCTGGGGTGATCCGGGTGAAGCAATACAAGCAGAGCCTGGCGATCGAGAGTGACGGCAAGAAGGGGAGCAAAGTTTTCATGTATTACT
TCGATAACCCGGGTGGCCAAATTCCGTCCTGGCTCATTAACTGGGCCGCCAAGAATCAGAGCAGAACCAAGCGGGAAGCTCAGAATCAGA
GAGACCTCATCAAGTTTTTGGCAAACCCAAACATTCTGCAATAGATTGAGTGGAAGGAAGAGGAAGGACATAAAGATAAAGACATGAGAA
AAGAAGCTGAGTCTTTGTTGAAACACTGAAATGGGTGCAGGTATCATTTCTTATCTCATTGTTTTTTCTCATAAGCCCTGAATTAATTCA
TTTATTCACAGTATTTTCGCAGATGTGAAATTCACATATTATTCACAGATGTGTTCACTATCATCTATGTACTGGAAAGATAGCAGTGAA

>In-frame_ENST00000322684_ENST00000573500_TCGA-D8-A27F-01A_MSI2_chr17_55339553_+_PCTP_chr17_53844696_length(amino acids)=272AA_start in transcript=35_stop in transcript=853
MADLTSVLTSVMFSPSSKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLGQPHHELDSKTIDPK
VAFPRRAQPKKTGLYEYKVFGVLEDCSPTLLADIYMDSDYRKQWDQYVKELYEQECNGETVVYWEVKYPFPMSNRDYVYLRQRRDLDMEG
RKIHVILARSTSMPQLGERSGVIRVKQYKQSLAIESDGKKGSKVFMYYFDNPGGQIPSWLINWAAKNQSRTKREAQNQRDLIKFLANPNI

--------------------------------------------------------------
>In-frame_ENST00000416426_ENST00000573500_TCGA-D8-A27F_MSI2_chr17_55339553_+_PCTP_chr17_53844695_length(transcript)=1149nt_BP=381nt
AGAGCCAGAGAGAACTTCCAGCGCAAAAGGAAAATAAAACTTGTGGCTGGTGTTTGTGCAGGAGGGTCTCCGCCATCCTGAAGCCCCCCG
ATCCTGGGGCGTCTCGGGGGCCGCCAAAGGAGCGCCAGGGTTAAAATGTTTATCGGTGGACTGAGCTGGCAGACCTCACCAGATAGCCTT
AGAGACTATTTTAGCAAATTTGGAGAAATTAGAGAATGTATGGTCATGAGAGATCCCACTACGAAACGCTCCAGAGGCTTCGGTTTCGTC
ACGTTCGCAGACCCAGCAAGTGTAGATAAAGTATTAGGTCAGCCCCACCATGAGTTAGATTCCAAGACGATTGACCCCAAAGTTGCATTT
CCTCGTCGAGCGCAACCCAAGAAGACTGGACTTTATGAGTATAAAGTCTTTGGTGTTCTGGAGGACTGCTCACCAACTCTACTGGCAGAC
ATCTATATGGACTCAGATTACAGAAAACAATGGGACCAGTATGTTAAAGAACTCTATGAACAAGAATGCAACGGAGAGACTGTGGTCTAC
TGGGAAGTGAAGTACCCTTTTCCCATGTCCAACAGAGACTATGTCTACCTTCGGCAGCGGCGAGACCTGGACATGGAAGGGAGGAAGATC
CATGTGATCCTGGCCCGGAGCACCTCCATGCCTCAGCTTGGCGAGAGGTCTGGGGTGATCCGGGTGAAGCAATACAAGCAGAGCCTGGCG
ATCGAGAGTGACGGCAAGAAGGGGAGCAAAGTTTTCATGTATTACTTCGATAACCCGGGTGGCCAAATTCCGTCCTGGCTCATTAACTGG
GCCGCCAAGAATCAGAGCAGAACCAAGCGGGAAGCTCAGAATCAGAGAGACCTCATCAAGTTTTTGGCAAACCCAAACATTCTGCAATAG
ATTGAGTGGAAGGAAGAGGAAGGACATAAAGATAAAGACATGAGAAAAGAAGCTGAGTCTTTGTTGAAACACTGAAATGGGTGCAGGTAT
CATTTCTTATCTCATTGTTTTTTCTCATAAGCCCTGAATTAATTCATTTATTCACAGTATTTTCGCAGATGTGAAATTCACATATTATTC

>In-frame_ENST00000416426_ENST00000573500_TCGA-D8-A27F_MSI2_chr17_55339553_+_PCTP_chr17_53844695_length(amino acids)=268AA_start in transcript=93_stop in transcript=899
MGRLGGRQRSARVKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLGQPHHELDSKTIDPKVAFP
RRAQPKKTGLYEYKVFGVLEDCSPTLLADIYMDSDYRKQWDQYVKELYEQECNGETVVYWEVKYPFPMSNRDYVYLRQRRDLDMEGRKIH

--------------------------------------------------------------
>In-frame_ENST00000284073_ENST00000573500_TCGA-D8-A27F_MSI2_chr17_55339553_+_PCTP_chr17_53844695_length(transcript)=1289nt_BP=521nt
CGGGGCTGAGCTAAGCCGAGCCCACGTGTGACGGCTCTCGCCGCTGCCCCGGCTCCGCCGCTCGCAGAGAGATTCGGAGGAGCCCGGGCG
GGGGGGAGGAGGAGGGGGAGGAGGGAGCGGAGATCTCGGGGCTCGGAGCCGGCCGCCGCTCCGCTCCGATCGCTGTGGGGCTTGGTTTTT
TGGGGGTGGGGGGGCGGGGGGGCTCAGATATGGAGGCAAATGGGAGCCAAGGCACCTCGGGCAGCGCCAACGACTCCCAGCACGACCCCG
GTAAAATGTTTATCGGTGGACTGAGCTGGCAGACCTCACCAGATAGCCTTAGAGACTATTTTAGCAAATTTGGAGAAATTAGAGAATGTA
TGGTCATGAGAGATCCCACTACGAAACGCTCCAGAGGCTTCGGTTTCGTCACGTTCGCAGACCCAGCAAGTGTAGATAAAGTATTAGGTC
AGCCCCACCATGAGTTAGATTCCAAGACGATTGACCCCAAAGTTGCATTTCCTCGTCGAGCGCAACCCAAGAAGACTGGACTTTATGAGT
ATAAAGTCTTTGGTGTTCTGGAGGACTGCTCACCAACTCTACTGGCAGACATCTATATGGACTCAGATTACAGAAAACAATGGGACCAGT
ATGTTAAAGAACTCTATGAACAAGAATGCAACGGAGAGACTGTGGTCTACTGGGAAGTGAAGTACCCTTTTCCCATGTCCAACAGAGACT
ATGTCTACCTTCGGCAGCGGCGAGACCTGGACATGGAAGGGAGGAAGATCCATGTGATCCTGGCCCGGAGCACCTCCATGCCTCAGCTTG
GCGAGAGGTCTGGGGTGATCCGGGTGAAGCAATACAAGCAGAGCCTGGCGATCGAGAGTGACGGCAAGAAGGGGAGCAAAGTTTTCATGT
ATTACTTCGATAACCCGGGTGGCCAAATTCCGTCCTGGCTCATTAACTGGGCCGCCAAGAATCAGAGCAGAACCAAGCGGGAAGCTCAGA
ATCAGAGAGACCTCATCAAGTTTTTGGCAAACCCAAACATTCTGCAATAGATTGAGTGGAAGGAAGAGGAAGGACATAAAGATAAAGACA
TGAGAAAAGAAGCTGAGTCTTTGTTGAAACACTGAAATGGGTGCAGGTATCATTTCTTATCTCATTGTTTTTTCTCATAAGCCCTGAATT
AATTCATTTATTCACAGTATTTTCGCAGATGTGAAATTCACATATTATTCACAGATGTGTTCACTATCATCTATGTACTGGAAAGATAGC

>In-frame_ENST00000284073_ENST00000573500_TCGA-D8-A27F_MSI2_chr17_55339553_+_PCTP_chr17_53844695_length(amino acids)=286AA_start in transcript=179_stop in transcript=1039
MGVGGRGGSDMEANGSQGTSGSANDSQHDPGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLG
QPHHELDSKTIDPKVAFPRRAQPKKTGLYEYKVFGVLEDCSPTLLADIYMDSDYRKQWDQYVKELYEQECNGETVVYWEVKYPFPMSNRD
YVYLRQRRDLDMEGRKIHVILARSTSMPQLGERSGVIRVKQYKQSLAIESDGKKGSKVFMYYFDNPGGQIPSWLINWAAKNQSRTKREAQ

--------------------------------------------------------------
>In-frame_ENST00000322684_ENST00000573500_TCGA-D8-A27F_MSI2_chr17_55339553_+_PCTP_chr17_53844695_length(transcript)=1103nt_BP=335nt
GCTTTCCTTTTAGCTTTTGTAAGTTACACGTCAAAATGGCCGATCTGACATCGGTGCTCACTTCTGTTATGTTTTCTCCCTCTAGTAAAA
TGTTTATCGGTGGACTGAGCTGGCAGACCTCACCAGATAGCCTTAGAGACTATTTTAGCAAATTTGGAGAAATTAGAGAATGTATGGTCA
TGAGAGATCCCACTACGAAACGCTCCAGAGGCTTCGGTTTCGTCACGTTCGCAGACCCAGCAAGTGTAGATAAAGTATTAGGTCAGCCCC
ACCATGAGTTAGATTCCAAGACGATTGACCCCAAAGTTGCATTTCCTCGTCGAGCGCAACCCAAGAAGACTGGACTTTATGAGTATAAAG
TCTTTGGTGTTCTGGAGGACTGCTCACCAACTCTACTGGCAGACATCTATATGGACTCAGATTACAGAAAACAATGGGACCAGTATGTTA
AAGAACTCTATGAACAAGAATGCAACGGAGAGACTGTGGTCTACTGGGAAGTGAAGTACCCTTTTCCCATGTCCAACAGAGACTATGTCT
ACCTTCGGCAGCGGCGAGACCTGGACATGGAAGGGAGGAAGATCCATGTGATCCTGGCCCGGAGCACCTCCATGCCTCAGCTTGGCGAGA
GGTCTGGGGTGATCCGGGTGAAGCAATACAAGCAGAGCCTGGCGATCGAGAGTGACGGCAAGAAGGGGAGCAAAGTTTTCATGTATTACT
TCGATAACCCGGGTGGCCAAATTCCGTCCTGGCTCATTAACTGGGCCGCCAAGAATCAGAGCAGAACCAAGCGGGAAGCTCAGAATCAGA
GAGACCTCATCAAGTTTTTGGCAAACCCAAACATTCTGCAATAGATTGAGTGGAAGGAAGAGGAAGGACATAAAGATAAAGACATGAGAA
AAGAAGCTGAGTCTTTGTTGAAACACTGAAATGGGTGCAGGTATCATTTCTTATCTCATTGTTTTTTCTCATAAGCCCTGAATTAATTCA
TTTATTCACAGTATTTTCGCAGATGTGAAATTCACATATTATTCACAGATGTGTTCACTATCATCTATGTACTGGAAAGATAGCAGTGAA

>In-frame_ENST00000322684_ENST00000573500_TCGA-D8-A27F_MSI2_chr17_55339553_+_PCTP_chr17_53844695_length(amino acids)=272AA_start in transcript=35_stop in transcript=853
MADLTSVLTSVMFSPSSKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLGQPHHELDSKTIDPK
VAFPRRAQPKKTGLYEYKVFGVLEDCSPTLLADIYMDSDYRKQWDQYVKELYEQECNGETVVYWEVKYPFPMSNRDYVYLRQRRDLDMEG
RKIHVILARSTSMPQLGERSGVIRVKQYKQSLAIESDGKKGSKVFMYYFDNPGGQIPSWLINWAAKNQSRTKREAQNQRDLIKFLANPNI

--------------------------------------------------------------
>In-frame_ENST00000416426_ENST00000573500_TCGA-D8-A27F-01A_MSI2_chr17_55339552_+_PCTP_chr17_53844695_length(transcript)=1149nt_BP=381nt
AGAGCCAGAGAGAACTTCCAGCGCAAAAGGAAAATAAAACTTGTGGCTGGTGTTTGTGCAGGAGGGTCTCCGCCATCCTGAAGCCCCCCG
ATCCTGGGGCGTCTCGGGGGCCGCCAAAGGAGCGCCAGGGTTAAAATGTTTATCGGTGGACTGAGCTGGCAGACCTCACCAGATAGCCTT
AGAGACTATTTTAGCAAATTTGGAGAAATTAGAGAATGTATGGTCATGAGAGATCCCACTACGAAACGCTCCAGAGGCTTCGGTTTCGTC
ACGTTCGCAGACCCAGCAAGTGTAGATAAAGTATTAGGTCAGCCCCACCATGAGTTAGATTCCAAGACGATTGACCCCAAAGTTGCATTT
CCTCGTCGAGCGCAACCCAAGAAGACTGGACTTTATGAGTATAAAGTCTTTGGTGTTCTGGAGGACTGCTCACCAACTCTACTGGCAGAC
ATCTATATGGACTCAGATTACAGAAAACAATGGGACCAGTATGTTAAAGAACTCTATGAACAAGAATGCAACGGAGAGACTGTGGTCTAC
TGGGAAGTGAAGTACCCTTTTCCCATGTCCAACAGAGACTATGTCTACCTTCGGCAGCGGCGAGACCTGGACATGGAAGGGAGGAAGATC
CATGTGATCCTGGCCCGGAGCACCTCCATGCCTCAGCTTGGCGAGAGGTCTGGGGTGATCCGGGTGAAGCAATACAAGCAGAGCCTGGCG
ATCGAGAGTGACGGCAAGAAGGGGAGCAAAGTTTTCATGTATTACTTCGATAACCCGGGTGGCCAAATTCCGTCCTGGCTCATTAACTGG
GCCGCCAAGAATCAGAGCAGAACCAAGCGGGAAGCTCAGAATCAGAGAGACCTCATCAAGTTTTTGGCAAACCCAAACATTCTGCAATAG
ATTGAGTGGAAGGAAGAGGAAGGACATAAAGATAAAGACATGAGAAAAGAAGCTGAGTCTTTGTTGAAACACTGAAATGGGTGCAGGTAT
CATTTCTTATCTCATTGTTTTTTCTCATAAGCCCTGAATTAATTCATTTATTCACAGTATTTTCGCAGATGTGAAATTCACATATTATTC

>In-frame_ENST00000416426_ENST00000573500_TCGA-D8-A27F-01A_MSI2_chr17_55339552_+_PCTP_chr17_53844695_length(amino acids)=268AA_start in transcript=93_stop in transcript=899
MGRLGGRQRSARVKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLGQPHHELDSKTIDPKVAFP
RRAQPKKTGLYEYKVFGVLEDCSPTLLADIYMDSDYRKQWDQYVKELYEQECNGETVVYWEVKYPFPMSNRDYVYLRQRRDLDMEGRKIH

--------------------------------------------------------------
>In-frame_ENST00000284073_ENST00000573500_TCGA-D8-A27F-01A_MSI2_chr17_55339552_+_PCTP_chr17_53844695_length(transcript)=1289nt_BP=521nt
CGGGGCTGAGCTAAGCCGAGCCCACGTGTGACGGCTCTCGCCGCTGCCCCGGCTCCGCCGCTCGCAGAGAGATTCGGAGGAGCCCGGGCG
GGGGGGAGGAGGAGGGGGAGGAGGGAGCGGAGATCTCGGGGCTCGGAGCCGGCCGCCGCTCCGCTCCGATCGCTGTGGGGCTTGGTTTTT
TGGGGGTGGGGGGGCGGGGGGGCTCAGATATGGAGGCAAATGGGAGCCAAGGCACCTCGGGCAGCGCCAACGACTCCCAGCACGACCCCG
GTAAAATGTTTATCGGTGGACTGAGCTGGCAGACCTCACCAGATAGCCTTAGAGACTATTTTAGCAAATTTGGAGAAATTAGAGAATGTA
TGGTCATGAGAGATCCCACTACGAAACGCTCCAGAGGCTTCGGTTTCGTCACGTTCGCAGACCCAGCAAGTGTAGATAAAGTATTAGGTC
AGCCCCACCATGAGTTAGATTCCAAGACGATTGACCCCAAAGTTGCATTTCCTCGTCGAGCGCAACCCAAGAAGACTGGACTTTATGAGT
ATAAAGTCTTTGGTGTTCTGGAGGACTGCTCACCAACTCTACTGGCAGACATCTATATGGACTCAGATTACAGAAAACAATGGGACCAGT
ATGTTAAAGAACTCTATGAACAAGAATGCAACGGAGAGACTGTGGTCTACTGGGAAGTGAAGTACCCTTTTCCCATGTCCAACAGAGACT
ATGTCTACCTTCGGCAGCGGCGAGACCTGGACATGGAAGGGAGGAAGATCCATGTGATCCTGGCCCGGAGCACCTCCATGCCTCAGCTTG
GCGAGAGGTCTGGGGTGATCCGGGTGAAGCAATACAAGCAGAGCCTGGCGATCGAGAGTGACGGCAAGAAGGGGAGCAAAGTTTTCATGT
ATTACTTCGATAACCCGGGTGGCCAAATTCCGTCCTGGCTCATTAACTGGGCCGCCAAGAATCAGAGCAGAACCAAGCGGGAAGCTCAGA
ATCAGAGAGACCTCATCAAGTTTTTGGCAAACCCAAACATTCTGCAATAGATTGAGTGGAAGGAAGAGGAAGGACATAAAGATAAAGACA
TGAGAAAAGAAGCTGAGTCTTTGTTGAAACACTGAAATGGGTGCAGGTATCATTTCTTATCTCATTGTTTTTTCTCATAAGCCCTGAATT
AATTCATTTATTCACAGTATTTTCGCAGATGTGAAATTCACATATTATTCACAGATGTGTTCACTATCATCTATGTACTGGAAAGATAGC

>In-frame_ENST00000284073_ENST00000573500_TCGA-D8-A27F-01A_MSI2_chr17_55339552_+_PCTP_chr17_53844695_length(amino acids)=286AA_start in transcript=179_stop in transcript=1039
MGVGGRGGSDMEANGSQGTSGSANDSQHDPGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLG
QPHHELDSKTIDPKVAFPRRAQPKKTGLYEYKVFGVLEDCSPTLLADIYMDSDYRKQWDQYVKELYEQECNGETVVYWEVKYPFPMSNRD
YVYLRQRRDLDMEGRKIHVILARSTSMPQLGERSGVIRVKQYKQSLAIESDGKKGSKVFMYYFDNPGGQIPSWLINWAAKNQSRTKREAQ

--------------------------------------------------------------
>In-frame_ENST00000322684_ENST00000573500_TCGA-D8-A27F-01A_MSI2_chr17_55339552_+_PCTP_chr17_53844695_length(transcript)=1103nt_BP=335nt
GCTTTCCTTTTAGCTTTTGTAAGTTACACGTCAAAATGGCCGATCTGACATCGGTGCTCACTTCTGTTATGTTTTCTCCCTCTAGTAAAA
TGTTTATCGGTGGACTGAGCTGGCAGACCTCACCAGATAGCCTTAGAGACTATTTTAGCAAATTTGGAGAAATTAGAGAATGTATGGTCA
TGAGAGATCCCACTACGAAACGCTCCAGAGGCTTCGGTTTCGTCACGTTCGCAGACCCAGCAAGTGTAGATAAAGTATTAGGTCAGCCCC
ACCATGAGTTAGATTCCAAGACGATTGACCCCAAAGTTGCATTTCCTCGTCGAGCGCAACCCAAGAAGACTGGACTTTATGAGTATAAAG
TCTTTGGTGTTCTGGAGGACTGCTCACCAACTCTACTGGCAGACATCTATATGGACTCAGATTACAGAAAACAATGGGACCAGTATGTTA
AAGAACTCTATGAACAAGAATGCAACGGAGAGACTGTGGTCTACTGGGAAGTGAAGTACCCTTTTCCCATGTCCAACAGAGACTATGTCT
ACCTTCGGCAGCGGCGAGACCTGGACATGGAAGGGAGGAAGATCCATGTGATCCTGGCCCGGAGCACCTCCATGCCTCAGCTTGGCGAGA
GGTCTGGGGTGATCCGGGTGAAGCAATACAAGCAGAGCCTGGCGATCGAGAGTGACGGCAAGAAGGGGAGCAAAGTTTTCATGTATTACT
TCGATAACCCGGGTGGCCAAATTCCGTCCTGGCTCATTAACTGGGCCGCCAAGAATCAGAGCAGAACCAAGCGGGAAGCTCAGAATCAGA
GAGACCTCATCAAGTTTTTGGCAAACCCAAACATTCTGCAATAGATTGAGTGGAAGGAAGAGGAAGGACATAAAGATAAAGACATGAGAA
AAGAAGCTGAGTCTTTGTTGAAACACTGAAATGGGTGCAGGTATCATTTCTTATCTCATTGTTTTTTCTCATAAGCCCTGAATTAATTCA
TTTATTCACAGTATTTTCGCAGATGTGAAATTCACATATTATTCACAGATGTGTTCACTATCATCTATGTACTGGAAAGATAGCAGTGAA

>In-frame_ENST00000322684_ENST00000573500_TCGA-D8-A27F-01A_MSI2_chr17_55339552_+_PCTP_chr17_53844695_length(amino acids)=272AA_start in transcript=35_stop in transcript=853
MADLTSVLTSVMFSPSSKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLGQPHHELDSKTIDPK
VAFPRRAQPKKTGLYEYKVFGVLEDCSPTLLADIYMDSDYRKQWDQYVKELYEQECNGETVVYWEVKYPFPMSNRDYVYLRQRRDLDMEG
RKIHVILARSTSMPQLGERSGVIRVKQYKQSLAIESDGKKGSKVFMYYFDNPGGQIPSWLINWAAKNQSRTKREAQNQRDLIKFLANPNI

--------------------------------------------------------------

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Fusion Gene PPI Analysis for MSI2-PCTP


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for MSI2-PCTP


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for MSI2-PCTP


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource