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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:MSI2-SYNPO2 (FusionGDB2 ID:55005)

Fusion Gene Summary for MSI2-SYNPO2

check button Fusion gene summary
Fusion gene informationFusion gene name: MSI2-SYNPO2
Fusion gene ID: 55005
HgeneTgene
Gene symbol

MSI2

SYNPO2

Gene ID

124540

171024

Gene namemusashi RNA binding protein 2synaptopodin 2
SynonymsMSI2H-
Cytomap

17q22

4q26

Type of geneprotein-codingprotein-coding
DescriptionRNA-binding protein Musashi homolog 2musashi homolog 2musashi-2synaptopodin-2genethonin-2myopodin
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000416426, ENST00000284073, 
ENST00000322684, ENST00000442934, 
ENST00000579180, ENST00000579505, 
ENST00000307142, ENST00000448416, 
ENST00000429713, ENST00000434046, 
Fusion gene scores* DoF score40 X 16 X 16=1024011 X 11 X 4=484
# samples 4512
** MAII scorelog2(45/10240*10)=-4.50814690367033
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(12/484*10)=-2.01197264166608
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: MSI2 [Title/Abstract] AND SYNPO2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointMSI2(55478832)-SYNPO2(119944585), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across MSI2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across SYNPO2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUSCTCGA-L3-A524-01AMSI2chr17

55478832

+SYNPO2chr4

119944585

+
ChimerDB4LUSCTCGA-L3-A524MSI2chr17

55478832

+SYNPO2chr4

119944585

+
ChimerDB4LUSCTCGA-L3-A524-01AMSI2chr17

55478832

-SYNPO2chr4

119944585

+


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Fusion Gene ORF analysis for MSI2-SYNPO2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000416426ENST00000307142MSI2chr17

55478832

+SYNPO2chr4

119944585

+
In-frameENST00000416426ENST00000448416MSI2chr17

55478832

+SYNPO2chr4

119944585

+
In-frameENST00000416426ENST00000429713MSI2chr17

55478832

+SYNPO2chr4

119944585

+
In-frameENST00000416426ENST00000434046MSI2chr17

55478832

+SYNPO2chr4

119944585

+
In-frameENST00000284073ENST00000307142MSI2chr17

55478832

+SYNPO2chr4

119944585

+
In-frameENST00000284073ENST00000448416MSI2chr17

55478832

+SYNPO2chr4

119944585

+
In-frameENST00000284073ENST00000429713MSI2chr17

55478832

+SYNPO2chr4

119944585

+
In-frameENST00000284073ENST00000434046MSI2chr17

55478832

+SYNPO2chr4

119944585

+
In-frameENST00000322684ENST00000307142MSI2chr17

55478832

+SYNPO2chr4

119944585

+
In-frameENST00000322684ENST00000448416MSI2chr17

55478832

+SYNPO2chr4

119944585

+
In-frameENST00000322684ENST00000429713MSI2chr17

55478832

+SYNPO2chr4

119944585

+
In-frameENST00000322684ENST00000434046MSI2chr17

55478832

+SYNPO2chr4

119944585

+
In-frameENST00000442934ENST00000307142MSI2chr17

55478832

+SYNPO2chr4

119944585

+
In-frameENST00000442934ENST00000448416MSI2chr17

55478832

+SYNPO2chr4

119944585

+
In-frameENST00000442934ENST00000429713MSI2chr17

55478832

+SYNPO2chr4

119944585

+
In-frameENST00000442934ENST00000434046MSI2chr17

55478832

+SYNPO2chr4

119944585

+
In-frameENST00000579180ENST00000307142MSI2chr17

55478832

+SYNPO2chr4

119944585

+
In-frameENST00000579180ENST00000448416MSI2chr17

55478832

+SYNPO2chr4

119944585

+
In-frameENST00000579180ENST00000429713MSI2chr17

55478832

+SYNPO2chr4

119944585

+
In-frameENST00000579180ENST00000434046MSI2chr17

55478832

+SYNPO2chr4

119944585

+
intron-3CDSENST00000579505ENST00000307142MSI2chr17

55478832

+SYNPO2chr4

119944585

+
intron-3CDSENST00000579505ENST00000448416MSI2chr17

55478832

+SYNPO2chr4

119944585

+
intron-3CDSENST00000579505ENST00000429713MSI2chr17

55478832

+SYNPO2chr4

119944585

+
intron-3CDSENST00000579505ENST00000434046MSI2chr17

55478832

+SYNPO2chr4

119944585

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000416426MSI2chr1755478832+ENST00000307142SYNPO2chr4119944585+74684749341541353
ENST00000416426MSI2chr1755478832+ENST00000448416SYNPO2chr4119944585+151847493740215
ENST00000416426MSI2chr1755478832+ENST00000429713SYNPO2chr4119944585+74294749336501185
ENST00000416426MSI2chr1755478832+ENST00000434046SYNPO2chr4119944585+38934749336981201
ENST00000284073MSI2chr1755478832+ENST00000307142SYNPO2chr4119944585+760861417942941371
ENST00000284073MSI2chr1755478832+ENST00000448416SYNPO2chr4119944585+1658614179880233
ENST00000284073MSI2chr1755478832+ENST00000429713SYNPO2chr4119944585+756961417937901203
ENST00000284073MSI2chr1755478832+ENST00000434046SYNPO2chr4119944585+403361417938381219
ENST00000322684MSI2chr1755478832+ENST00000307142SYNPO2chr4119944585+74224283541081357
ENST00000322684MSI2chr1755478832+ENST00000448416SYNPO2chr4119944585+147242835694219
ENST00000322684MSI2chr1755478832+ENST00000429713SYNPO2chr4119944585+73834283536041189
ENST00000322684MSI2chr1755478832+ENST00000434046SYNPO2chr4119944585+38474283536521205
ENST00000442934MSI2chr1755478832+ENST00000307142SYNPO2chr4119944585+72562624039421300
ENST00000442934MSI2chr1755478832+ENST00000448416SYNPO2chr4119944585+130626240528162
ENST00000442934MSI2chr1755478832+ENST00000429713SYNPO2chr4119944585+72172624034381132
ENST00000442934MSI2chr1755478832+ENST00000434046SYNPO2chr4119944585+36812624034861148
ENST00000579180MSI2chr1755478832+ENST00000307142SYNPO2chr4119944585+719219810538781257
ENST00000579180MSI2chr1755478832+ENST00000448416SYNPO2chr4119944585+1242198105464119
ENST00000579180MSI2chr1755478832+ENST00000429713SYNPO2chr4119944585+715319810533741089
ENST00000579180MSI2chr1755478832+ENST00000434046SYNPO2chr4119944585+361719810534221105

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000416426ENST00000307142MSI2chr1755478832+SYNPO2chr4119944585+0.0001314480.9998685
ENST00000416426ENST00000448416MSI2chr1755478832+SYNPO2chr4119944585+0.0031823110.9968177
ENST00000416426ENST00000429713MSI2chr1755478832+SYNPO2chr4119944585+0.0001864360.9998136
ENST00000416426ENST00000434046MSI2chr1755478832+SYNPO2chr4119944585+0.0009359790.999064
ENST00000284073ENST00000307142MSI2chr1755478832+SYNPO2chr4119944585+0.0001509720.99984896
ENST00000284073ENST00000448416MSI2chr1755478832+SYNPO2chr4119944585+0.0020325840.9979674
ENST00000284073ENST00000429713MSI2chr1755478832+SYNPO2chr4119944585+0.0002164610.9997836
ENST00000284073ENST00000434046MSI2chr1755478832+SYNPO2chr4119944585+0.0011083730.99889165
ENST00000322684ENST00000307142MSI2chr1755478832+SYNPO2chr4119944585+0.000114820.9998852
ENST00000322684ENST00000448416MSI2chr1755478832+SYNPO2chr4119944585+0.0009496120.99905044
ENST00000322684ENST00000429713MSI2chr1755478832+SYNPO2chr4119944585+0.0001639580.99983597
ENST00000322684ENST00000434046MSI2chr1755478832+SYNPO2chr4119944585+0.0008144020.9991856
ENST00000442934ENST00000307142MSI2chr1755478832+SYNPO2chr4119944585+0.0001107550.99988925
ENST00000442934ENST00000448416MSI2chr1755478832+SYNPO2chr4119944585+0.0039255970.99607444
ENST00000442934ENST00000429713MSI2chr1755478832+SYNPO2chr4119944585+0.0001553160.9998447
ENST00000442934ENST00000434046MSI2chr1755478832+SYNPO2chr4119944585+0.000800410.99919957
ENST00000579180ENST00000307142MSI2chr1755478832+SYNPO2chr4119944585+0.0001270450.9998729
ENST00000579180ENST00000448416MSI2chr1755478832+SYNPO2chr4119944585+0.0220574010.97794265
ENST00000579180ENST00000429713MSI2chr1755478832+SYNPO2chr4119944585+0.0001898850.99981016
ENST00000579180ENST00000434046MSI2chr1755478832+SYNPO2chr4119944585+0.0010585090.9989415

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Fusion Genomic Features for MSI2-SYNPO2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for MSI2-SYNPO2


check button Go to

FGviewer for the breakpoints of chr17:55478832-chr4:119944585

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneMSI2chr17:55478832chr4:119944585ENST00000284073+61421_111135.01951.0DomainRRM 1
HgeneMSI2chr17:55478832chr4:119944585ENST00000322684+51021_111131.0252.0DomainRRM 1
TgeneSYNPO2chr17:55478832chr4:119944585ENST0000030714205400_40535.01262.0Compositional biasNote=Poly-Arg
TgeneSYNPO2chr17:55478832chr4:119944585ENST0000030714205423_42635.01262.0Compositional biasNote=Poly-Glu
TgeneSYNPO2chr17:55478832chr4:119944585ENST0000030714205591_65835.01262.0Compositional biasNote=Pro-rich
TgeneSYNPO2chr17:55478832chr4:119944585ENST0000030714205756_81835.01262.0Compositional biasNote=Pro-rich
TgeneSYNPO2chr17:55478832chr4:119944585ENST0000030714205767_77035.01262.0Compositional biasNote=Poly-Ser
TgeneSYNPO2chr17:55478832chr4:119944585ENST0000042971304400_40535.01094.0Compositional biasNote=Poly-Arg
TgeneSYNPO2chr17:55478832chr4:119944585ENST0000042971304423_42635.01094.0Compositional biasNote=Poly-Glu
TgeneSYNPO2chr17:55478832chr4:119944585ENST0000042971304591_65835.01094.0Compositional biasNote=Pro-rich
TgeneSYNPO2chr17:55478832chr4:119944585ENST0000042971304756_81835.01094.0Compositional biasNote=Pro-rich
TgeneSYNPO2chr17:55478832chr4:119944585ENST0000042971304767_77035.01094.0Compositional biasNote=Poly-Ser
TgeneSYNPO2chr17:55478832chr4:119944585ENST0000043404605400_40535.01110.0Compositional biasNote=Poly-Arg
TgeneSYNPO2chr17:55478832chr4:119944585ENST0000043404605423_42635.01110.0Compositional biasNote=Poly-Glu
TgeneSYNPO2chr17:55478832chr4:119944585ENST0000043404605591_65835.01110.0Compositional biasNote=Pro-rich
TgeneSYNPO2chr17:55478832chr4:119944585ENST0000043404605756_81835.01110.0Compositional biasNote=Pro-rich
TgeneSYNPO2chr17:55478832chr4:119944585ENST0000043404605767_77035.01110.0Compositional biasNote=Poly-Ser
TgeneSYNPO2chr17:55478832chr4:119944585ENST0000030714205398_40635.01262.0MotifNuclear localization signal
TgeneSYNPO2chr17:55478832chr4:119944585ENST0000030714205619_62235.01262.0MotifPPPY motif
TgeneSYNPO2chr17:55478832chr4:119944585ENST0000042971304398_40635.01094.0MotifNuclear localization signal
TgeneSYNPO2chr17:55478832chr4:119944585ENST0000042971304619_62235.01094.0MotifPPPY motif
TgeneSYNPO2chr17:55478832chr4:119944585ENST0000043404605398_40635.01110.0MotifNuclear localization signal
TgeneSYNPO2chr17:55478832chr4:119944585ENST0000043404605619_62235.01110.0MotifPPPY motif
TgeneSYNPO2chr17:55478832chr4:119944585ENST0000030714205534_66335.01262.0RegionF-actin binding
TgeneSYNPO2chr17:55478832chr4:119944585ENST0000030714205664_80335.01262.0RegionF-actin binding
TgeneSYNPO2chr17:55478832chr4:119944585ENST0000030714205664_91635.01262.0RegionF-actin bundling activity
TgeneSYNPO2chr17:55478832chr4:119944585ENST0000030714205751_90035.01262.0RegionActin binding
TgeneSYNPO2chr17:55478832chr4:119944585ENST0000042971304534_66335.01094.0RegionF-actin binding
TgeneSYNPO2chr17:55478832chr4:119944585ENST0000042971304664_80335.01094.0RegionF-actin binding
TgeneSYNPO2chr17:55478832chr4:119944585ENST0000042971304664_91635.01094.0RegionF-actin bundling activity
TgeneSYNPO2chr17:55478832chr4:119944585ENST0000042971304751_90035.01094.0RegionActin binding
TgeneSYNPO2chr17:55478832chr4:119944585ENST0000043404605534_66335.01110.0RegionF-actin binding
TgeneSYNPO2chr17:55478832chr4:119944585ENST0000043404605664_80335.01110.0RegionF-actin binding
TgeneSYNPO2chr17:55478832chr4:119944585ENST0000043404605664_91635.01110.0RegionF-actin bundling activity
TgeneSYNPO2chr17:55478832chr4:119944585ENST0000043404605751_90035.01110.0RegionActin binding

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneMSI2chr17:55478832chr4:119944585ENST00000284073+614253_260135.01951.0Compositional biasNote=Poly-Ala
HgeneMSI2chr17:55478832chr4:119944585ENST00000322684+510253_260131.0252.0Compositional biasNote=Poly-Ala
HgeneMSI2chr17:55478832chr4:119944585ENST00000579180+27253_26031.0152.0Compositional biasNote=Poly-Ala
HgeneMSI2chr17:55478832chr4:119944585ENST00000284073+614110_187135.01951.0DomainRRM 2
HgeneMSI2chr17:55478832chr4:119944585ENST00000322684+510110_187131.0252.0DomainRRM 2
HgeneMSI2chr17:55478832chr4:119944585ENST00000579180+27110_18731.0152.0DomainRRM 2
HgeneMSI2chr17:55478832chr4:119944585ENST00000579180+2721_11131.0152.0DomainRRM 1
TgeneSYNPO2chr17:55478832chr4:119944585ENST00000307142056_8835.01262.0DomainPDZ
TgeneSYNPO2chr17:55478832chr4:119944585ENST00000429713046_8835.01094.0DomainPDZ
TgeneSYNPO2chr17:55478832chr4:119944585ENST00000434046056_8835.01110.0DomainPDZ


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Fusion Gene Sequence for MSI2-SYNPO2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000416426_ENST00000307142_TCGA-L3-A524-01A_MSI2_chr17_55478832_+_SYNPO2_chr4_119944585_length(transcript)=7468nt_BP=474nt
AGAGCCAGAGAGAACTTCCAGCGCAAAAGGAAAATAAAACTTGTGGCTGGTGTTTGTGCAGGAGGGTCTCCGCCATCCTGAAGCCCCCCG
ATCCTGGGGCGTCTCGGGGGCCGCCAAAGGAGCGCCAGGGTTAAAATGTTTATCGGTGGACTGAGCTGGCAGACCTCACCAGATAGCCTT
AGAGACTATTTTAGCAAATTTGGAGAAATTAGAGAATGTATGGTCATGAGAGATCCCACTACGAAACGCTCCAGAGGCTTCGGTTTCGTC
ACGTTCGCAGACCCAGCAAGTGTAGATAAAGTATTAGGTCAGCCCCACCATGAGTTAGATTCCAAGACGATTGACCCCAAAGTTGCATTT
CCTCGTCGAGCGCAACCCAAGATGGTCACAAGAACAAAGAAAATATTTGTAGGCGGGTTATCTGCGAACACAGTAGTGGAAGATGTAAAG
CAATATTTCGAGCAGTTTGGCAAGATTCGAAATCAGAGCAAAGCCTCTGGGTCTGGGCTCTGTGAGGGAGATGAAGTGGTTTCCATCAAT
GGCAACCCTTGTGCAGATCTCACCTACCCTGAAGTCATCAAGCTCATGGAAAGCATAACAGACTCTCTCCAAATGCTCATCAAAAGACCA
TCCAGTGGAATAAGTGAGGCTTTGATATCTGAAAATGAAAACAAAAACCTCGAGCATCTCACACATGGGGGTTATGTGGAAAGTACCACC
CTGCAGATTCGACCGGCCACAAAGACCCAGTGCACAGAATTCTTCCTCGCCCCTGTCAAGACTGAAGTTCCCCTAGCTGAGAACCAAAGA
AGTGGTCCCGACTGTGCAGGCAGCTTGAAAGAAGAAACAGGCCCGAGCTACCAAAGGGCTCCCCAAATGCCTGACTCCCAAAGAGGACGC
GTGGCAGAAGAGCTGATCTTAAGGGAGAAGGTAGAAGCGGTACAGCCTGGGCCTGTGGTTGAGCTGCAACTGTCCCTTTCACAGGAGAGA
CATAAGGGCGCTAGTGGCCCTTTAGTGGCTCTCCCGGGAGCTGAAAAATCTAAGTCTCCTGACCCAGACCCTAACTTGTCACATGACAGG
ATTGTCCACATAAATTCGATCCCTACTAATGAGAAAGCAGACCCTTTCCTGAGGTCCAGCAAGATAATCCAGATCTCCAGTGGCAGAGAG
TTGAGAGTGATCCAGGAAAGTGAAGCAGGAGATGCGGGACTGCCCCGGGTGGAAGTGATCCTCGACTGCTCTGACAGGCAGAAGACAGAA
GGGTGCAGGCTTCAGGCAGGAAAGGAGTGTGTGGATTCTCCAGTGGAAGGAGGGCAGTCAGAAGCACCTCCTTCTCTGGTATCCTTTGCC
GTCTCATCAGAAGGCACAGAGCAGGGAGAAGATCCACGCTCGGAAAAAGATCACAGCAGACCTCACAAGCACCGAGCGCGGCATGCACGG
CTCAGGAGGAGTGAAAGCCTGTCAGAAAAACAAGTGAAGGAAGCAAAATCTAAATGCAAAAGCATTGCCCTTCTTCTAACGGATGCTCCC
AACCCCAACTCCAAGGGGGTGTTGATGTTTAAGAAGCGACGTCGGAGGGCCAGGAAATACACCCTAGTTAGCTACGGTACTGGCGAGCTT
GAGCGAGAGGCGGACGAGGAGGAAGAAGGTGACAAGGAGGATACATGTGAAGTAGCATTTCTTGGTGCAAGCGAATCAGAGGTGGATGAA
GAGTTATTGTCTGACGTTGACGACAACACACAAGTTGTGAACTTTGACTGGGATTCTGGACTGGTGGACATTGAAAAGAAACTGAACAGA
GGGGACAAGATGGAGATGTTACCAGACACCACAGGCAAGGGAGCCCTCATGTTTGCCAAGAGGAGGGAGAGAATGGATCAGATCACAGCC
CAAAAAGAAGAGGACAAGGTAGGTGGAACGCCAAGCAGAGAACAAGATGCTGCCCAGACCGATGGCCTGAGAACCACGACTTCTTACCAA
AGAAAGGAGGAAGAGTCGGTAAGAACGCAGAGCTCTGTGAGCAAAAGCTACATCGAGGTGAGTCATGGTCTTGGCCATGTTCCCCAACAG
AATGGCTTCAGTGGGACATCTGAGACAGCAAACATCCAGAGGATGGTCCCCATGAATAGAACGGCCAAACCCTTCCCAGGGTCTGTGAAT
CAGCCAGCTACCCCCTTCTCGCCAACCCGAAACATGACGAGTCCCATTGCTGACTTTCCTGCACCTCCACCTTACTCTGCAGTCACTCCT
CCCCCTGACGCCTTCTCCAGAGGGGTTTCAAGTCCGATTGCTGGCCCAGCACAGCCCCCTCCATGGCCCCAGCCTGCCCCGTGGTCCCAG
CCAGCCTTTTACGATTCGTCTGAGCGAATAGCTTCCCGAGATGAGAGGATCTCAGTGCCAGCAAAAAGAACAGGAATATTGCAGGAGGCC
AAAAGGAGAAGCACGACAAAACCCATGTTTACTTTTAAAGAGCCCAAAGTAAGCCCAAATCCTGAACTCTTGTCACTCCTTCAAAATTCA
GAAGGCAAACGGGGCACTGGAGCTGGAGGTGATTCCGGACCGGAAGAAGACTACCTCAGCTTGGGGGCAGAGGCTTGTAATTTCATGCAA
AGCTCCTCTGCCAAACAAAAGACCCCTCCTCCTGTTGCTCCAAAACCTGCAGTCAAGTCCTCATCCTCCCAACCAGTAACTCCAGTTTCC
CCAGTCTGGTCTCCAGGAGTGGCTCCCACCCAACCTCCTGCCTTCCCCACATCCAACCCATCAAAGGGCACCGTTGTCTCCTCCATCAAA
ATAGCCCAGCCTTCTTACCCTCCTGCCCGGCCTGCAAGTACTTTGAACGTGGCTGGTCCCTTCAAAGGACCACAAGCAGCAGTAGCCAGT
CAGAATTACACACCCAAACCAACAGTTTCCACACCAACAGTCAATGCTGTTCAGCCTGGTGCAGTGGGACCATCCAATGAGCTTCCAGGA
ATGAGTGGGAGAGGAGCTCAGCTCTTTGCTAAAAGGCAGTCGAGAATGGAGAAGTATGTGGTCGATTCAGACACGGTGCAGGCCCACGCT
GCTCGAGCTCAGTCTCCCACTCCATCTCTCCCGGCCAGTTGGAAGTACTCCTCCAATGTCCGAGCACCTCCTCCTGTGGCCTATAATCCT
ATCCACTCGCCGTCTTACCCACTGGCTGCTCTCAAGTCTCAGCCATCAGCTGCACAGCCCTCCAAAATGGGCAAGAAAAAGGGAAAGAAA
CCCCTCAATGCATTAGATGTCATGAAGCACCAACCGTATCAGCTCAATGCATCCTTGTTTACTTTCCAACCTCCAGATGCAAAGGATGGC
CTCCCCCAGAAGTCATCAGTCAAGGTCAATTCAGCCCTGGCCATGAAGCAAGCTCTTCCTCCCCGGCCAGTGAATGCTGCCTCACCTACG
AATGTGCAGGCTTCGTCAGTGTACTCGGTACCAGCCTATACCTCTCCTCCTTCCTTCTTTGCAGAGGCCTCCTCACCAGTCAGTGCATCC
CCAGTGCCTGTGGGCATTCCCACCTCGCCAAAGCAAGAATCAGCCTCATCATCTTATTTTGTGGCACCAAGGCCAAAGTTCTCAGCCAAG
AAAAGTGGTGTCACAATTCAGGAGAGTGGGCGCTCCCTTTCTCTTCCTGGAAGATCAGTCCCACCCCCCATTTCTACATCTCCTTGGGTA
TACCAGCCTACTTATAGTTACTCTAGTAAACCAACCGATGGACTAGAGAAAGCAAACAAGAGACCAACTCCTTGGGAAGCAGCAGCAAAG
TCTCCTCTCGGTCTAGTGGATGATGCTTTCCAACCCAGAAACATCCAGGAATCCATTGTGGCAAATGTGGTTTCAGCAGCTCGGAGGAAG
GTGCTTCCAGGGCCTCCAGAGGATTGGAATGAAAGACTGTCCTATATTCCTCAAACCCAGAAGGCCTATATGGGCTCATGTGGAAGGCAA
GAGTATAATGTCACAGCCAATAATAATATGTCCACCACCTCCCAATATGGTTCACAGTTGCCATATGCATATTATAGGCAGGCTTCAAGA
AATGATTCTGCAATCATGTCCATGGAAACCAGGTCTGATTACTGTCTTCCAGTAGCTGATTACAACTACAACCCACACCCAAGGGGATGG
AGACGCCAAACATGAAAGTTAGAAGAACGGATCATGTGCCAACTGTAGTTTTTTAAAAAAAACGCTCCTTTGTAGGGTTTTAAACTTTTC
TAATAGATTTAGATTCACTTTTGGTCTTGGCTTGTTCTCATAAGTCATTTATCTAAGTTTGTGTTTCTGTGTGTGTGTGTGTGTGTGTAT
GTATGTGAATATACACACACACACACACACAGGTGAGTGTGAATACTTCCTTGTTGGCTGATCCATAGAGCATTACTTGGAAGAAAATTT
CACTATTTGCATTGATGTGCTGGCATTTATATGTAATTCATAATTTTGATTCCATTAATAGGTAGTCTATGCAACAAACTCTACTCAATT
AAAGTAAAACTAAGTATTTCTTCATTGTACCTTAGTCCAGGAAGAAATTAATGGAATATGGTGTGCTAATTATCACTACCTATAACATGA
GGAATATAACATTGCAGAAATTTCTCATAGGGGCATGCCAGTGAGCAATTACTTTATAAAAATATTTTCCTTGGTGTTAAGTATTTCTCT
GCAACTTTTTTTTTTTTTTTTTTTTTTTTTTGAGATGGAGTCTTGCTCTGTCCCACCCAGTCTGGAGTGCAATGGTGCGATCTTGGCTCA
CTGCAACCTGCGCCTCCTGGGTTCAAGCAATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGCATGAACCACCACACCTGGAT
AATTTTTGTATTTTTAGTAGACACAAAGTTTCACCATGTTGGTCAGACTGGTCTTGAACTCCTGACCTCGTGATCTGCCCGCCTCAGCCT
CCCAAAGTGCTGGGATTACAGGCGTGAGCCACCACACCTGGCCTTTCTGCAACATTTTTTTAAAAAAATCTAATAAATCTTAGATTTTTA
AAAAAGAATTAAAATGTGGGAGTTCTCAGAAAGAAATAAACACATGAGAATAAGATTATTACACATTTTGGAAGGACTTTTGAGGAATGA
TGTGATGTGTAGAGAATAGAAAGATTTAGATATATGCCTGTGACAGGAATAGATTCTGGGTTCAGGGGTCCCCATCTGTCAAATGAGAAG
ATTGGATTATCTAATCTTTTAGATCCTTAACAACTCTGATATTCTGAGATTCTCTCATTTGTAGAATGCCCGCTGATGCATTGTTTATTT
TTTTTGCTCATAATATAAATATCAGATTATGTTTAGGAGTGGATTAGGTAATTAGTGTCACTACATGTATCATTAAAGGTCCTAAAAGGA
ATTGTTAGGCGGCAGGCTTTGTGTTACGTGTTACATGGAGTGAGGGTAGATGTGAAGATTTAAAACGATTGATGGATTTAAGGAAGTGGT
ACATAAATATGTCTGTTATTATGCAATCGTAGGTCATGATAATTTATTCAGTTATAGAAAACATGCCACAGAAGCCTATGTAACAAGTGG
TGCTTCTTTAGAAAGTTGTCATTAGAATGTTCTGAGGAAGTTAAGCAGCTGCTTCATCAATCCCATGACACATGCCTTGTTAGCATGCCC
ATCAAATAATCAGATCAAACACCTGCTCCTTATTGCCATACCCACGAACTGTTAAATATAAAAAAATTCAAAGTATTTGACATCTTAAGC
AAATATCCAGAATATTTTTAAGTAAAAAACCATCTTAAGTATTCAAAATTTCCTTGGTTTTTTAAAGGTGATAATTTTGCTTTGTGTTAC
TTTTTTGCTCTTGAATGTATCGTTATGATGGTCTCTTATAATCATGGTATCTTTCACAGAATAAAAATTAAAAATAATGCCAGGGTGCAA
GTGACCAAGGCCTTATCTTGAAAGTTAAAAAAAAAAAGTAAAGAAATCACAGTAAGTTCTATTAGTGATGATAGAACCAGATATAAAATT
GTTCAGTGATGGAGAAAAGAAACGATAAATACTTTCCAAGGTTATATTGTTAAATTATCTTAAATTATCAAGGTGTAAGATGTAATGATC
CCAAGAGTTTTTATAGAATCCTAAAAAATAACGCCTGATGTATAGATTAGTTAGCAAATTCTCAGAAATCCCCCACATAAAAGCCTTACT
TTGTTCAAAATTTATTATAGTGGTTTAATCATTTTAGATTTGAATGTTTTAAGATAGGAGAGACTTAGCAGAAAATACTTGGCTTGCCAG
GGCCACGTTCTACTTCATTGCTTTCTTTTATAAGTGCAAGGAGTTATTTCCATCAGTTGACATAGATATTATTCACTAAAATTTTCAGCA
GACTCAAAATAGAGAGGAGACTTTAAACTTACATGTTAGCATAAAACAGACTTCTCTCTCATTGCATGCACTAGATCAATATTATCATCT
GTATTAAGCTATCTGAATTTATTCGAGACATTAAGAAAAAGACAGTACATGGTGGGAAAGCTGCACATTTCTCACAAGGAAAAAAACATT
CTATATTTGTAGCAGAAATCAGTGGTTTGAAAAGTCATACTTTGCAGATATGAACCTGAAAATCAAAGTGCCATTGTTAAATCATCCTAA
AGTGTACTGTGGGTATTCTCCAGCATACTTGAAAATGAATAAAGTTAGATTGCTCACATTGAAGCTAATGGTTGAGACAAGACACCTGCC
AGAGTGAAGTTTGATTCCTATGGGTGAGAAGATGTAGATGACTATTGTTCTCACTAAAGTTCTAAAATAATAGCAAGTGTAGAGAAGAGC
CGTTGCTTTGAAAATACATACCACATTTGTTATAAAGCATTTGTTTGTTAGTATCAATCACATAGGTAGAAAGAGTTTGAGTTTTACTGT
GGATTAAAAAGCCTTCCCTAAAAAGAGAGCATGCCAGTCATAGAGACACTAATTTGGCACTTTTCCTCCTTCTTAGGTTTAAATGTTATA
CCAATGCATGTGTTTGAAATATCCATTAAGATGATTTAAAATTTGTCTTGTATTTTGAGTTTCTTAAATGCGTGGATTCTTGTTCATTTA
TCTCTGAATATGTCTCTTTTATATTTTGGCACAATTATACACATTGGAAAGGGCCAACCTATTAGGGCTCAAGTATGTATATGCAAAAAA
AAAAAGTTATATCAAACAGGCACAGTTATTACAACTAGAGAGAAATTCCAGAAATATTTGTTTTTTTAAGAGAAAGTAAATTTTCACATT
AGATTTCTATTCAAAGTACTAATATCTACATGGTCCACACTTTTCTATTTTAAAAAATTGTGTTCTCTTGTTAAATAGATTAACATTTCC

>In-frame_ENST00000416426_ENST00000307142_TCGA-L3-A524-01A_MSI2_chr17_55478832_+_SYNPO2_chr4_119944585_length(amino acids)=1353AA_start in transcript=93_stop in transcript=4154
MGRLGGRQRSARVKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLGQPHHELDSKTIDPKVAFP
RRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKIRNQSKASGSGLCEGDEVVSINGNPCADLTYPEVIKLMESITDSLQMLIKRPS
SGISEALISENENKNLEHLTHGGYVESTTLQIRPATKTQCTEFFLAPVKTEVPLAENQRSGPDCAGSLKEETGPSYQRAPQMPDSQRGRV
AEELILREKVEAVQPGPVVELQLSLSQERHKGASGPLVALPGAEKSKSPDPDPNLSHDRIVHINSIPTNEKADPFLRSSKIIQISSGREL
RVIQESEAGDAGLPRVEVILDCSDRQKTEGCRLQAGKECVDSPVEGGQSEAPPSLVSFAVSSEGTEQGEDPRSEKDHSRPHKHRARHARL
RRSESLSEKQVKEAKSKCKSIALLLTDAPNPNSKGVLMFKKRRRRARKYTLVSYGTGELEREADEEEEGDKEDTCEVAFLGASESEVDEE
LLSDVDDNTQVVNFDWDSGLVDIEKKLNRGDKMEMLPDTTGKGALMFAKRRERMDQITAQKEEDKVGGTPSREQDAAQTDGLRTTTSYQR
KEEESVRTQSSVSKSYIEVSHGLGHVPQQNGFSGTSETANIQRMVPMNRTAKPFPGSVNQPATPFSPTRNMTSPIADFPAPPPYSAVTPP
PDAFSRGVSSPIAGPAQPPPWPQPAPWSQPAFYDSSERIASRDERISVPAKRTGILQEAKRRSTTKPMFTFKEPKVSPNPELLSLLQNSE
GKRGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTPVSPVWSPGVAPTQPPAFPTSNPSKGTVVSSIKI
AQPSYPPARPASTLNVAGPFKGPQAAVASQNYTPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAA
RAQSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLNALDVMKHQPYQLNASLFTFQPPDAKDGL
PQKSSVKVNSALAMKQALPPRPVNAASPTNVQASSVYSVPAYTSPPSFFAEASSPVSASPVPVGIPTSPKQESASSSYFVAPRPKFSAKK
SGVTIQESGRSLSLPGRSVPPPISTSPWVYQPTYSYSSKPTDGLEKANKRPTPWEAAAKSPLGLVDDAFQPRNIQESIVANVVSAARRKV
LPGPPEDWNERLSYIPQTQKAYMGSCGRQEYNVTANNNMSTTSQYGSQLPYAYYRQASRNDSAIMSMETRSDYCLPVADYNYNPHPRGWR

--------------------------------------------------------------
>In-frame_ENST00000416426_ENST00000448416_TCGA-L3-A524-01A_MSI2_chr17_55478832_+_SYNPO2_chr4_119944585_length(transcript)=1518nt_BP=474nt
AGAGCCAGAGAGAACTTCCAGCGCAAAAGGAAAATAAAACTTGTGGCTGGTGTTTGTGCAGGAGGGTCTCCGCCATCCTGAAGCCCCCCG
ATCCTGGGGCGTCTCGGGGGCCGCCAAAGGAGCGCCAGGGTTAAAATGTTTATCGGTGGACTGAGCTGGCAGACCTCACCAGATAGCCTT
AGAGACTATTTTAGCAAATTTGGAGAAATTAGAGAATGTATGGTCATGAGAGATCCCACTACGAAACGCTCCAGAGGCTTCGGTTTCGTC
ACGTTCGCAGACCCAGCAAGTGTAGATAAAGTATTAGGTCAGCCCCACCATGAGTTAGATTCCAAGACGATTGACCCCAAAGTTGCATTT
CCTCGTCGAGCGCAACCCAAGATGGTCACAAGAACAAAGAAAATATTTGTAGGCGGGTTATCTGCGAACACAGTAGTGGAAGATGTAAAG
CAATATTTCGAGCAGTTTGGCAAGATTCGAAATCAGAGCAAAGCCTCTGGGTCTGGGCTCTGTGAGGGAGATGAAGTGGTTTCCATCAAT
GGCAACCCTTGTGCAGATCTCACCTACCCTGAAGTCATCAAGCTCATGGAAAGCATAACAGACTCTCTCCAAATGCTCATCAAAAGGAGA
GTGGGCGCTCCCTTTCTCTTCCTGGAAGATCAGTCCCACCCCCCATTTCTACATCTCCTTGGGTATACCAGCCTACTTATAGTTACTCTA
GTAAACCAACCGATGGACTAGAGAAAGCAAACAAGAGACCAACTCCTTGGGAAGCAGCAGCAAAGTCTCCTCTCGGTCTAGTGGATGATG
CTTTCCAACCCAGAAACATCCAGGAATCCATTGTGGCAAATGTGGTTTCAGCAGCTCGGAGGAAGGTGCTTCCAGGGCCTCCAGAGGATT
GGAATGAAAGACTGTCCTATATTCCTCAAACCCAGAAGGCCTATATGGGCTCATGTGGAAGGCAAGAGTATAATGTCACAGCCAATAATA
ATATGTCCACCACCTCCCAATATGGTTCACAGTTGCCATATGCATATTATAGGCAGGCTTCAAGAAATGATTCTGCAATCATGTCCATGG
AAACCAGGTCTGATTACTGTCTTCCAGTAGCTGATTACAACTACAACCCACACCCAAGGGGATGGAGACGCCAAACATGAAAGTTAGAAG
AACGGATCATGTGCCAACTGTAGTTTTTTAAAAAAAACGCTCCTTTGTAGGGTTTTAAACTTTTCTAATAGATTTAGATTCACTTTTGGT
CTTGGCTTGTTCTCATAAGTCATTTATCTAAGTTTGTGTTTCTGTGTGTGTGTGTGTGTGTGTATGTATGTGAATATACACACACACACA
CACACAGGTGAGTGTGAATACTTCCTTGTTGGCTGATCCATAGAGCATTACTTGGAAGAAAATTTCACTATTTGCATTGATGTGCTGGCA

>In-frame_ENST00000416426_ENST00000448416_TCGA-L3-A524-01A_MSI2_chr17_55478832_+_SYNPO2_chr4_119944585_length(amino acids)=215AA_start in transcript=93_stop in transcript=740
MGRLGGRQRSARVKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLGQPHHELDSKTIDPKVAFP
RRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKIRNQSKASGSGLCEGDEVVSINGNPCADLTYPEVIKLMESITDSLQMLIKRRV

--------------------------------------------------------------
>In-frame_ENST00000416426_ENST00000429713_TCGA-L3-A524-01A_MSI2_chr17_55478832_+_SYNPO2_chr4_119944585_length(transcript)=7429nt_BP=474nt
AGAGCCAGAGAGAACTTCCAGCGCAAAAGGAAAATAAAACTTGTGGCTGGTGTTTGTGCAGGAGGGTCTCCGCCATCCTGAAGCCCCCCG
ATCCTGGGGCGTCTCGGGGGCCGCCAAAGGAGCGCCAGGGTTAAAATGTTTATCGGTGGACTGAGCTGGCAGACCTCACCAGATAGCCTT
AGAGACTATTTTAGCAAATTTGGAGAAATTAGAGAATGTATGGTCATGAGAGATCCCACTACGAAACGCTCCAGAGGCTTCGGTTTCGTC
ACGTTCGCAGACCCAGCAAGTGTAGATAAAGTATTAGGTCAGCCCCACCATGAGTTAGATTCCAAGACGATTGACCCCAAAGTTGCATTT
CCTCGTCGAGCGCAACCCAAGATGGTCACAAGAACAAAGAAAATATTTGTAGGCGGGTTATCTGCGAACACAGTAGTGGAAGATGTAAAG
CAATATTTCGAGCAGTTTGGCAAGATTCGAAATCAGAGCAAAGCCTCTGGGTCTGGGCTCTGTGAGGGAGATGAAGTGGTTTCCATCAAT
GGCAACCCTTGTGCAGATCTCACCTACCCTGAAGTCATCAAGCTCATGGAAAGCATAACAGACTCTCTCCAAATGCTCATCAAAAGACCA
TCCAGTGGAATAAGTGAGGCTTTGATATCTGAAAATGAAAACAAAAACCTCGAGCATCTCACACATGGGGGTTATGTGGAAAGTACCACC
CTGCAGATTCGACCGGCCACAAAGACCCAGTGCACAGAATTCTTCCTCGCCCCTGTCAAGACTGAAGTTCCCCTAGCTGAGAACCAAAGA
AGTGGTCCCGACTGTGCAGGCAGCTTGAAAGAAGAAACAGGCCCGAGCTACCAAAGGGCTCCCCAAATGCCTGACTCCCAAAGAGGACGC
GTGGCAGAAGAGCTGATCTTAAGGGAGAAGGTAGAAGCGGTACAGCCTGGGCCTGTGGTTGAGCTGCAACTGTCCCTTTCACAGGAGAGA
CATAAGGGCGCTAGTGGCCCTTTAGTGGCTCTCCCGGGAGCTGAAAAATCTAAGTCTCCTGACCCAGACCCTAACTTGTCACATGACAGG
ATTGTCCACATAAATTCGATCCCTACTAATGAGAAAGCAGACCCTTTCCTGAGGTCCAGCAAGATAATCCAGATCTCCAGTGGCAGAGAG
TTGAGAGTGATCCAGGAAAGTGAAGCAGGAGATGCGGGACTGCCCCGGGTGGAAGTGATCCTCGACTGCTCTGACAGGCAGAAGACAGAA
GGGTGCAGGCTTCAGGCAGGAAAGGAGTGTGTGGATTCTCCAGTGGAAGGAGGGCAGTCAGAAGCACCTCCTTCTCTGGTATCCTTTGCC
GTCTCATCAGAAGGCACAGAGCAGGGAGAAGATCCACGCTCGGAAAAAGATCACAGCAGACCTCACAAGCACCGAGCGCGGCATGCACGG
CTCAGGAGGAGTGAAAGCCTGTCAGAAAAACAAGTGAAGGAAGCAAAATCTAAATGCAAAAGCATTGCCCTTCTTCTAACGGATGCTCCC
AACCCCAACTCCAAGGGGGTGTTGATGTTTAAGAAGCGACGTCGGAGGGCCAGGAAATACACCCTAGTTAGCTACGGTACTGGCGAGCTT
GAGCGAGAGGCGGACGAGGAGGAAGAAGGTGACAAGGAGGATACATGTGAAGTAGCATTTCTTGGTGCAAGCGAATCAGAGGTGGATGAA
GAGTTATTGTCTGACGTTGACGACAACACACAAGTTGTGAACTTTGACTGGGATTCTGGACTGGTGGACATTGAAAAGAAACTGAACAGA
GGGGACAAGATGGAGATGTTACCAGACACCACAGGCAAGGGAGCCCTCATGTTTGCCAAGAGGAGGGAGAGAATGGATCAGATCACAGCC
CAAAAAGAAGAGGACAAGGTAGGTGGAACGCCAAGCAGAGAACAAGATGCTGCCCAGACCGATGGCCTGAGAACCACGACTTCTTACCAA
AGAAAGGAGGAAGAGTCGGTAAGAACGCAGAGCTCTGTGAGCAAAAGCTACATCGAGGTGAGTCATGGTCTTGGCCATGTTCCCCAACAG
AATGGCTTCAGTGGGACATCTGAGACAGCAAACATCCAGAGGATGGTCCCCATGAATAGAACGGCCAAACCCTTCCCAGGGTCTGTGAAT
CAGCCAGCTACCCCCTTCTCGCCAACCCGAAACATGACGAGTCCCATTGCTGACTTTCCTGCACCTCCACCTTACTCTGCAGTCACTCCT
CCCCCTGACGCCTTCTCCAGAGGGGTTTCAAGTCCGATTGCTGGCCCAGCACAGCCCCCTCCATGGCCCCAGCCTGCCCCGTGGTCCCAG
CCAGCCTTTTACGATTCGTCTGAGCGAATAGCTTCCCGAGATGAGAGGATCTCAGTGCCAGCAAAAAGAACAGGAATATTGCAGGAGGCC
AAAAGGAGAAGCACGACAAAACCCATGTTTACTTTTAAAGAGCCCAAAGTAAGCCCAAATCCTGAACTCTTGTCACTCCTTCAAAATTCA
GAAGGCAAACGGGGCACTGGAGCTGGAGGTGATTCCGGACCGGAAGAAGACTACCTCAGCTTGGGGGCAGAGGCTTGTAATTTCATGCAA
AGCTCCTCTGCCAAACAAAAGACCCCTCCTCCTGTTGCTCCAAAACCTGCAGTCAAGTCCTCATCCTCCCAACCAGTAACTCCAGTTTCC
CCAGTCTGGTCTCCAGGAGTGGCTCCCACCCAACCTCCTGCCTTCCCCACATCCAACCCATCAAAGGGCACCGTTGTCTCCTCCATCAAA
ATAGCCCAGCCTTCTTACCCTCCTGCCCGGCCTGCAAGTACTTTGAACGTGGCTGGTCCCTTCAAAGGACCACAAGCAGCAGTAGCCAGT
CAGAATTACACACCCAAACCAACAGTTTCCACACCAACAGTCAATGCTGTTCAGCCTGGTGCAGTGGGACCATCCAATGAGCTTCCAGGA
ATGAGTGGGAGAGGAGCTCAGCTCTTTGCTAAAAGGCAGTCGAGAATGGAGAAGTATGTGGTCGATTCAGACACGGTGCAGGCCCACGCT
GCTCGAGCTCAGTCTCCCACTCCATCTCTCCCGGCCAGTTGGAAGTACTCCTCCAATGTCCGAGCACCTCCTCCTGTGGCCTATAATCCT
ATCCACTCGCCGTCTTACCCACTGGCTGCTCTCAAGTCTCAGCCATCAGCTGCACAGCCCTCCAAAATGGGCAAGAAAAAGGGAAAGAAA
CCCCTCAATGCATTAGATGTCATGAAGCACCAACCGTATCAGCTCAATGCATCCTTGTTTACTTTCCAACCTCCAGATGCAAAGGATGGC
CTCCCCCAGAAGTCATCAGTCAAGGTCAATTCAGCCCTGGCCATGAAGCAAGCTCTTCCTCCCCGGCCAGTGAATGCTGCCTCACCTACG
AATGTGCAGGCTTCGTCAGTGTACTCGGTACCAGCCTATACCTCTCCTCCTTCCTTCTTTGCAGAGGCCTCCTCACCAGTCAGTGCATCC
CCAGTGCCTGTGGGCATTCCCACCTCGCCAAAGCAAGAATCAGCCTCATCATCTTATTTTGTGGCACCAAGGCCAAAGTTCTCAGCCAAG
AAAAGTGGTGTCACAATTCAGGTGTGGAAACCATCTGTTGTGGAAGAGTAATCTTGTAGCTGAAGCTGAGTGTCCACTTTGCTTGAAATG
AATTGTTTGCAGTGTTTCTTGAGTCCCTGAGAATGCCTAGCAAAGTCCTCAACTTACTTAATTTCAGATATGTCACCTCCTAATCTGGGT
CCAAGGAGTATAATATTTTTAATGAGTCAAAAATCCAACTCAGATTGACCTAAAATATATTTATCTTCTTTGCACACTTAAAAAATCCAG
GAGCACCCCAAAATAGACATGTACCGTTATATTAAGTAAGCAGGAGACTTAGGATTTGTGCTGTAGCCACAAGAAAGACAGTGATCAGTG
ATATCAAACATCAGGAATCAGCCTTTATGTAACATAACAGCTGTCCTCCTATGGTGAAAGGTTCAAATGTAGTGAAGGTATAACCTATAT
TGACTGAGATTTCCCTTTTAGGTAGTGCCTTATCTCTATTACTAGTGTTAAAGGAATAAGGAATCTATGAAGGACAGGGAGCAGCTCTGG
TCTGTCAATCTCAGCCACCTGTTTGATATCACAGAGAAGATACTCGGAGGATTGTTGGAATGTATATAGTTTAGTAAGAAGTGGGTAAGA
AAGAGGGTCTTAATTACTGAGCACTTATTATGTATTAGGTTCTTTGCCAGATGTTTTTACATATATAAACTCATTTCAGAAAACTTATTT
AAAGTAAATGGGGCCGGGTATGGTGGTTCATGCCTGGAATCCTAGCACTTTGGGAGGCTGAGGTAGGAGGACTGCTTGAGGCCGGGAGTT
GGAGACCAGCCTGAGCAACATAGTGAGACCCTGTCTCAATAATAATAATAATAATAGTAATAATGAAGTAAATGGGATAAGGAAAGAAGG
ATAATTATCTTTAAAGGTTGATTCCCACCCTCCCTCCCCAGTTACTTAAGGAACTAAGTGAGTACATCTCCAGTTGCCCATGAAAGCATA
AGTTTGTTTTCCTCAGCTGAGGCAAGTGGTAGAGTATACAGGATAACGAAGTAACATGTAAAAGGCAGGACGCACATAAAGGTGTACATG
GCTATTGTTTCACCTGGAGAAACCACATGATTGGGACCTGAAGGTTTACTGACTGACTACAGGGGCTGATTGTGAAGCACGAGGAACCCC
ATGTGTGTGGAGACTGTAGGGTGAGAGCACACAATTATTAGCATCATTTCTGAGTGATCTCACAGATTTTTTTTCTTGTGTTTGCTTTGC
TTTTTGACAACTGCTTCTCCCACGTTCCTTGCAATTCTATTCTCTCACCTTCACTTTACTATTTGTATTCGATGGACCAGGATAATTCAG
GCAAGGTTACCTTGTAAACTTTAATTGGCCACACACCATGTTGTCACCCAGCTGGCTATGAAGTGAATAATGGTACTGAAAGTAAACCTG
AAGACCTTTCTCAGATCTATTTTAAGTCTGAGTCTGACCAACCATGGAAAATATTCGACATGAATTAATGTAGAGAACTATAAAGCATTT
ATGACAGCTCCAAGAAAAATCATCTACTCTATGCAGGAGATATGTTTAGAGACCTCTCAGAAAAACTTGCCTGGTTTGAGGGTACACAGT
ACCATTTTAATCTTCTGAAAATATCTGTATTCCTGCTCTTTTTCTGCTGTCACTGTCAATCTGCTATATTTTTCACTATCCTATTAAAAT
ATTACTGTCTCCTTTATCTGTTCAATGTCCATATTTTAAAAAAATCTTCCTTGTATGAGCTATTCTGATCTAAATAATTTCTCTGATATT
TCTCTATATGGCTCCCACAACAATTTCATTGTTGTTAGCATATCTATTTCTCCATACATTGTAAAACTGTAATCCTTAGGTATTTCTAAA
ACATAAAGAGGAGAATTAAGTCAGCTGCAGAACAATGGGGCTGATTCTTCTGCTTTTTCTCTGGAAAATCTTTCATTGCTTTTGGTGGAA
ATTTACCTAGAGGTTACAACCACAGGATGTAGCTTGGTCTCTTATTTGCCTTTTTGGGAAACCAATTAAGATTAATACAGGATAAAGGAA
AAAAGCAATCTATTCATTATATAACACAGTTGTTTGTATTACTTGTTCCCTGCAAAGGAAATCTGTTGAATGCTTGCATTTTGAATTCTT
TTCTAATAGAACAACCAAAAAAGGCTTCTTATGGTGCAGCAGGAAAAAAGATCATTTTTATAGCTTTGCATTCTTAACATAGCATTTAAA
GAGCGGCATGAATTAGAGGAAAGACATGGAACACACAGGTAGTCGGTTTGAGATCATCGGCTTAAAAGTATCCTAGGATGGTAATGACCC
AGAAGTATTTCCAGTTGTCTAGTGGTGTGGTATGCAGGAATGAGAAGTGTTTTCTTTCCATTTCCTGTTGGACAGGTGGCAATCTTAGCA
GAGCCACTATTTGGAGTTGATAACTAAAGATGCAAATAACATGACTATGCCTTCTGGTCATCCTAGGACTATTTGGAGTTCTCCAAAACC
TTGTAAGAGGCATGTCAGGCATGCAGTAAAAGCATCTACAACTTCAGCTGGGCACTGGCAGCATAGGTCTCATCTTGGACCATACAGTCC
CACTTTATAGAAGAGGGTGGAAGTTCTCCAAAACAATATCCACAACAAAGTCTGACCTCACTCTGAGGGAGATGGGAAGTGGGAGGAAGA
AGGACTAACCAGCTCCCTGGAGTAAGAGGAATTTGCTTTCCCTGTCTGCCCACCAGGGGCTATATGTGCCACCTTTCAGGTTGGGGCCAA
GGAAGTGATGTCAGTGTGACAGAAGGGAGAGTTAGACCTCCAGACGTCAGCCTCCCTCCCATGGGGTACATTTTCAATCTGAGTGTTGTT
GCCTTAGCTGTGTTGGTATTAGCTTGATTGGTTGGTCCGCTGGTTATGAGGTGTAGGGAGGCAGTTTTTGTTTAGTTTTTAGGACTTTGC
CTCTTCCTTTGTCCTTAGCATAATTTCTAGGCAGAGCATCCACGAAGTCGGTTTTCATTGCCAGCTCAAGAGCGACAATCATTTACGAGT
TCCTATGTTATGTTAGGTGCCTTATGTATATTATCCCAAATCCACTGCATGGTTTAAATACAGGCACTGGAATATAAATGAAAAAGGTCA
TTACAGTCACTGACTTTCTGCAGGACCTTAAACATTTCTCTTTCCACAAGTTTCCCCTTAATCATGTGTCAAACCTCTCTTCCTGACGGG
AATGTTGTGCTATAATGAATCTGCATAACGCTTGGGATTCTAGGAGGAAGGAAGGTTCCATGGACATGTAAGTACAGCATATTCCCCTCA
GTCTTCTAGGAGGGCAGAGTGAATCCCAGAACTGGTAAGATTGGGAATCTGAGCATTGCCACTTTAATCTTAGAATATTTATCATTTTGA
CACATCCTGTTTTTTAGAGAGGAAAACAAACACAGTTTCTGCATTGGTAGTGTAAAGCATACCTTGTTAGGAACGTGTTTTGTAAGACAC
ATTTGGGTTGTCACTCTAGAGCATGTCAAACTTTGTACTTCAAAATATATTTAGTATGATTGTTAGTGGTAACATATATCAAGGCTTTGA
ATTAACTGTTTTATTTAATTTTCACAAGAAGCACTTATTTTAGCCATAGGAAAACCAATCTGAGCTACAAATAGTTCTTTAAAATAAGCC
CAGGTTATTTAGCTATTCTAGAAAGTGCCGACTTCTTTCAAGAAGCAGGCATTGTAGGACAGCTGAGAATTATCACATAGCCTAAATTCT

>In-frame_ENST00000416426_ENST00000429713_TCGA-L3-A524-01A_MSI2_chr17_55478832_+_SYNPO2_chr4_119944585_length(amino acids)=1185AA_start in transcript=93_stop in transcript=3650
MGRLGGRQRSARVKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLGQPHHELDSKTIDPKVAFP
RRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKIRNQSKASGSGLCEGDEVVSINGNPCADLTYPEVIKLMESITDSLQMLIKRPS
SGISEALISENENKNLEHLTHGGYVESTTLQIRPATKTQCTEFFLAPVKTEVPLAENQRSGPDCAGSLKEETGPSYQRAPQMPDSQRGRV
AEELILREKVEAVQPGPVVELQLSLSQERHKGASGPLVALPGAEKSKSPDPDPNLSHDRIVHINSIPTNEKADPFLRSSKIIQISSGREL
RVIQESEAGDAGLPRVEVILDCSDRQKTEGCRLQAGKECVDSPVEGGQSEAPPSLVSFAVSSEGTEQGEDPRSEKDHSRPHKHRARHARL
RRSESLSEKQVKEAKSKCKSIALLLTDAPNPNSKGVLMFKKRRRRARKYTLVSYGTGELEREADEEEEGDKEDTCEVAFLGASESEVDEE
LLSDVDDNTQVVNFDWDSGLVDIEKKLNRGDKMEMLPDTTGKGALMFAKRRERMDQITAQKEEDKVGGTPSREQDAAQTDGLRTTTSYQR
KEEESVRTQSSVSKSYIEVSHGLGHVPQQNGFSGTSETANIQRMVPMNRTAKPFPGSVNQPATPFSPTRNMTSPIADFPAPPPYSAVTPP
PDAFSRGVSSPIAGPAQPPPWPQPAPWSQPAFYDSSERIASRDERISVPAKRTGILQEAKRRSTTKPMFTFKEPKVSPNPELLSLLQNSE
GKRGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTPVSPVWSPGVAPTQPPAFPTSNPSKGTVVSSIKI
AQPSYPPARPASTLNVAGPFKGPQAAVASQNYTPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAA
RAQSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLNALDVMKHQPYQLNASLFTFQPPDAKDGL
PQKSSVKVNSALAMKQALPPRPVNAASPTNVQASSVYSVPAYTSPPSFFAEASSPVSASPVPVGIPTSPKQESASSSYFVAPRPKFSAKK

--------------------------------------------------------------
>In-frame_ENST00000416426_ENST00000434046_TCGA-L3-A524-01A_MSI2_chr17_55478832_+_SYNPO2_chr4_119944585_length(transcript)=3893nt_BP=474nt
AGAGCCAGAGAGAACTTCCAGCGCAAAAGGAAAATAAAACTTGTGGCTGGTGTTTGTGCAGGAGGGTCTCCGCCATCCTGAAGCCCCCCG
ATCCTGGGGCGTCTCGGGGGCCGCCAAAGGAGCGCCAGGGTTAAAATGTTTATCGGTGGACTGAGCTGGCAGACCTCACCAGATAGCCTT
AGAGACTATTTTAGCAAATTTGGAGAAATTAGAGAATGTATGGTCATGAGAGATCCCACTACGAAACGCTCCAGAGGCTTCGGTTTCGTC
ACGTTCGCAGACCCAGCAAGTGTAGATAAAGTATTAGGTCAGCCCCACCATGAGTTAGATTCCAAGACGATTGACCCCAAAGTTGCATTT
CCTCGTCGAGCGCAACCCAAGATGGTCACAAGAACAAAGAAAATATTTGTAGGCGGGTTATCTGCGAACACAGTAGTGGAAGATGTAAAG
CAATATTTCGAGCAGTTTGGCAAGATTCGAAATCAGAGCAAAGCCTCTGGGTCTGGGCTCTGTGAGGGAGATGAAGTGGTTTCCATCAAT
GGCAACCCTTGTGCAGATCTCACCTACCCTGAAGTCATCAAGCTCATGGAAAGCATAACAGACTCTCTCCAAATGCTCATCAAAAGACCA
TCCAGTGGAATAAGTGAGGCTTTGATATCTGAAAATGAAAACAAAAACCTCGAGCATCTCACACATGGGGGTTATGTGGAAAGTACCACC
CTGCAGATTCGACCGGCCACAAAGACCCAGTGCACAGAATTCTTCCTCGCCCCTGTCAAGACTGAAGTTCCCCTAGCTGAGAACCAAAGA
AGTGGTCCCGACTGTGCAGGCAGCTTGAAAGAAGAAACAGGCCCGAGCTACCAAAGGGCTCCCCAAATGCCTGACTCCCAAAGAGGACGC
GTGGCAGAAGAGCTGATCTTAAGGGAGAAGGTAGAAGCGGTACAGCCTGGGCCTGTGGTTGAGCTGCAACTGTCCCTTTCACAGGAGAGA
CATAAGGGCGCTAGTGGCCCTTTAGTGGCTCTCCCGGGAGCTGAAAAATCTAAGTCTCCTGACCCAGACCCTAACTTGTCACATGACAGG
ATTGTCCACATAAATTCGATCCCTACTAATGAGAAAGCAGACCCTTTCCTGAGGTCCAGCAAGATAATCCAGATCTCCAGTGGCAGAGAG
TTGAGAGTGATCCAGGAAAGTGAAGCAGGAGATGCGGGACTGCCCCGGGTGGAAGTGATCCTCGACTGCTCTGACAGGCAGAAGACAGAA
GGGTGCAGGCTTCAGGCAGGAAAGGAGTGTGTGGATTCTCCAGTGGAAGGAGGGCAGTCAGAAGCACCTCCTTCTCTGGTATCCTTTGCC
GTCTCATCAGAAGGCACAGAGCAGGGAGAAGATCCACGCTCGGAAAAAGATCACAGCAGACCTCACAAGCACCGAGCGCGGCATGCACGG
CTCAGGAGGAGTGAAAGCCTGTCAGAAAAACAAGTGAAGGAAGCAAAATCTAAATGCAAAAGCATTGCCCTTCTTCTAACGGATGCTCCC
AACCCCAACTCCAAGGGGGTGTTGATGTTTAAGAAGCGACGTCGGAGGGCCAGGAAATACACCCTAGTTAGCTACGGTACTGGCGAGCTT
GAGCGAGAGGCGGACGAGGAGGAAGAAGGTGACAAGGAGGATACATGTGAAGTAGCATTTCTTGGTGCAAGCGAATCAGAGGTGGATGAA
GAGTTATTGTCTGACGTTGACGACAACACACAAGTTGTGAACTTTGACTGGGATTCTGGACTGGTGGACATTGAAAAGAAACTGAACAGA
GGGGACAAGATGGAGATGTTACCAGACACCACAGGCAAGGGAGCCCTCATGTTTGCCAAGAGGAGGGAGAGAATGGATCAGATCACAGCC
CAAAAAGAAGAGGACAAGGTAGGTGGAACGCCAAGCAGAGAACAAGATGCTGCCCAGACCGATGGCCTGAGAACCACGACTTCTTACCAA
AGAAAGGAGGAAGAGTCGGTAAGAACGCAGAGCTCTGTGAGCAAAAGCTACATCGAGGTGAGTCATGGTCTTGGCCATGTTCCCCAACAG
AATGGCTTCAGTGGGACATCTGAGACAGCAAACATCCAGAGGATGGTCCCCATGAATAGAACGGCCAAACCCTTCCCAGGGTCTGTGAAT
CAGCCAGCTACCCCCTTCTCGCCAACCCGAAACATGACGAGTCCCATTGCTGACTTTCCTGCACCTCCACCTTACTCTGCAGTCACTCCT
CCCCCTGACGCCTTCTCCAGAGGGGTTTCAAGTCCGATTGCTGGCCCAGCACAGCCCCCTCCATGGCCCCAGCCTGCCCCGTGGTCCCAG
CCAGCCTTTTACGATTCGTCTGAGCGAATAGCTTCCCGAGATGAGAGGATCTCAGTGCCAGCAAAAAGAACAGGAATATTGCAGGAGGCC
AAAAGGAGAAGCACGACAAAACCCATGTTTACTTTTAAAGAGCCCAAAGTAAGCCCAAATCCTGAACTCTTGTCACTCCTTCAAAATTCA
GAAGGCAAACGGGGCACTGGAGCTGGAGGTGATTCCGGACCGGAAGAAGACTACCTCAGCTTGGGGGCAGAGGCTTGTAATTTCATGCAA
AGCTCCTCTGCCAAACAAAAGACCCCTCCTCCTGTTGCTCCAAAACCTGCAGTCAAGTCCTCATCCTCCCAACCAGTAACTCCAGTTTCC
CCAGTCTGGTCTCCAGGAGTGGCTCCCACCCAACCTCCTGCCTTCCCCACATCCAACCCATCAAAGGGCACCGTTGTCTCCTCCATCAAA
ATAGCCCAGCCTTCTTACCCTCCTGCCCGGCCTGCAAGTACTTTGAACGTGGCTGGTCCCTTCAAAGGACCACAAGCAGCAGTAGCCAGT
CAGAATTACACACCCAAACCAACAGTTTCCACACCAACAGTCAATGCTGTTCAGCCTGGTGCAGTGGGACCATCCAATGAGCTTCCAGGA
ATGAGTGGGAGAGGAGCTCAGCTCTTTGCTAAAAGGCAGTCGAGAATGGAGAAGTATGTGGTCGATTCAGACACGGTGCAGGCCCACGCT
GCTCGAGCTCAGTCTCCCACTCCATCTCTCCCGGCCAGTTGGAAGTACTCCTCCAATGTCCGAGCACCTCCTCCTGTGGCCTATAATCCT
ATCCACTCGCCGTCTTACCCACTGGCTGCTCTCAAGTCTCAGCCATCAGCTGCACAGCCCTCCAAAATGGGCAAGAAAAAGGGAAAGAAA
CCCCTCAATGCATTAGATGTCATGAAGCACCAACCGTATCAGCTCAATGCATCCTTGTTTACTTTCCAACCTCCAGATGCAAAGGATGGC
CTCCCCCAGAAGTCATCAGTCAAGGTCAATTCAGCCCTGGCCATGAAGCAAGCTCTTCCTCCCCGGCCAGTGAATGCTGCCTCACCTACG
AATGTGCAGGCTTCGTCAGTGTACTCGGTACCAGCCTATACCTCTCCTCCTTCCTTCTTTGCAGAGGCCTCCTCACCAGTCAGTGCATCC
CCAGTGCCTGTGGGCATTCCCACCTCGCCAAAGCAAGAATCAGCCTCATCATCTTATTTTGTGGCACCAAGGCCAAAGTTCTCAGCCAAG
AAAAGTGGTGTCACAATTCAGGTGAAATGTAAATCTGGGATCCATAGTCAAGATATCATAAGGACCTACTTCCCAGCCTACCTTTCTTCC
TCTACCTGATAATGATAATACTCAAAATAACAACATTCAAAGGAAACACAAAGAAATCCTGCTTTCACATCTCCTATTTCTTGGGCTCCT
TAATAACTACTGATGGTTTGTTCATGAAAAAAAATTTTTAAATCAAAAGATTGTACTTGGCCCTGAGTTGAAAAAATTTCAAAAATCAAA

>In-frame_ENST00000416426_ENST00000434046_TCGA-L3-A524-01A_MSI2_chr17_55478832_+_SYNPO2_chr4_119944585_length(amino acids)=1201AA_start in transcript=93_stop in transcript=3698
MGRLGGRQRSARVKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLGQPHHELDSKTIDPKVAFP
RRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKIRNQSKASGSGLCEGDEVVSINGNPCADLTYPEVIKLMESITDSLQMLIKRPS
SGISEALISENENKNLEHLTHGGYVESTTLQIRPATKTQCTEFFLAPVKTEVPLAENQRSGPDCAGSLKEETGPSYQRAPQMPDSQRGRV
AEELILREKVEAVQPGPVVELQLSLSQERHKGASGPLVALPGAEKSKSPDPDPNLSHDRIVHINSIPTNEKADPFLRSSKIIQISSGREL
RVIQESEAGDAGLPRVEVILDCSDRQKTEGCRLQAGKECVDSPVEGGQSEAPPSLVSFAVSSEGTEQGEDPRSEKDHSRPHKHRARHARL
RRSESLSEKQVKEAKSKCKSIALLLTDAPNPNSKGVLMFKKRRRRARKYTLVSYGTGELEREADEEEEGDKEDTCEVAFLGASESEVDEE
LLSDVDDNTQVVNFDWDSGLVDIEKKLNRGDKMEMLPDTTGKGALMFAKRRERMDQITAQKEEDKVGGTPSREQDAAQTDGLRTTTSYQR
KEEESVRTQSSVSKSYIEVSHGLGHVPQQNGFSGTSETANIQRMVPMNRTAKPFPGSVNQPATPFSPTRNMTSPIADFPAPPPYSAVTPP
PDAFSRGVSSPIAGPAQPPPWPQPAPWSQPAFYDSSERIASRDERISVPAKRTGILQEAKRRSTTKPMFTFKEPKVSPNPELLSLLQNSE
GKRGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTPVSPVWSPGVAPTQPPAFPTSNPSKGTVVSSIKI
AQPSYPPARPASTLNVAGPFKGPQAAVASQNYTPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAA
RAQSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLNALDVMKHQPYQLNASLFTFQPPDAKDGL
PQKSSVKVNSALAMKQALPPRPVNAASPTNVQASSVYSVPAYTSPPSFFAEASSPVSASPVPVGIPTSPKQESASSSYFVAPRPKFSAKK

--------------------------------------------------------------
>In-frame_ENST00000284073_ENST00000307142_TCGA-L3-A524-01A_MSI2_chr17_55478832_+_SYNPO2_chr4_119944585_length(transcript)=7608nt_BP=614nt
CGGGGCTGAGCTAAGCCGAGCCCACGTGTGACGGCTCTCGCCGCTGCCCCGGCTCCGCCGCTCGCAGAGAGATTCGGAGGAGCCCGGGCG
GGGGGGAGGAGGAGGGGGAGGAGGGAGCGGAGATCTCGGGGCTCGGAGCCGGCCGCCGCTCCGCTCCGATCGCTGTGGGGCTTGGTTTTT
TGGGGGTGGGGGGGCGGGGGGGCTCAGATATGGAGGCAAATGGGAGCCAAGGCACCTCGGGCAGCGCCAACGACTCCCAGCACGACCCCG
GTAAAATGTTTATCGGTGGACTGAGCTGGCAGACCTCACCAGATAGCCTTAGAGACTATTTTAGCAAATTTGGAGAAATTAGAGAATGTA
TGGTCATGAGAGATCCCACTACGAAACGCTCCAGAGGCTTCGGTTTCGTCACGTTCGCAGACCCAGCAAGTGTAGATAAAGTATTAGGTC
AGCCCCACCATGAGTTAGATTCCAAGACGATTGACCCCAAAGTTGCATTTCCTCGTCGAGCGCAACCCAAGATGGTCACAAGAACAAAGA
AAATATTTGTAGGCGGGTTATCTGCGAACACAGTAGTGGAAGATGTAAAGCAATATTTCGAGCAGTTTGGCAAGATTCGAAATCAGAGCA
AAGCCTCTGGGTCTGGGCTCTGTGAGGGAGATGAAGTGGTTTCCATCAATGGCAACCCTTGTGCAGATCTCACCTACCCTGAAGTCATCA
AGCTCATGGAAAGCATAACAGACTCTCTCCAAATGCTCATCAAAAGACCATCCAGTGGAATAAGTGAGGCTTTGATATCTGAAAATGAAA
ACAAAAACCTCGAGCATCTCACACATGGGGGTTATGTGGAAAGTACCACCCTGCAGATTCGACCGGCCACAAAGACCCAGTGCACAGAAT
TCTTCCTCGCCCCTGTCAAGACTGAAGTTCCCCTAGCTGAGAACCAAAGAAGTGGTCCCGACTGTGCAGGCAGCTTGAAAGAAGAAACAG
GCCCGAGCTACCAAAGGGCTCCCCAAATGCCTGACTCCCAAAGAGGACGCGTGGCAGAAGAGCTGATCTTAAGGGAGAAGGTAGAAGCGG
TACAGCCTGGGCCTGTGGTTGAGCTGCAACTGTCCCTTTCACAGGAGAGACATAAGGGCGCTAGTGGCCCTTTAGTGGCTCTCCCGGGAG
CTGAAAAATCTAAGTCTCCTGACCCAGACCCTAACTTGTCACATGACAGGATTGTCCACATAAATTCGATCCCTACTAATGAGAAAGCAG
ACCCTTTCCTGAGGTCCAGCAAGATAATCCAGATCTCCAGTGGCAGAGAGTTGAGAGTGATCCAGGAAAGTGAAGCAGGAGATGCGGGAC
TGCCCCGGGTGGAAGTGATCCTCGACTGCTCTGACAGGCAGAAGACAGAAGGGTGCAGGCTTCAGGCAGGAAAGGAGTGTGTGGATTCTC
CAGTGGAAGGAGGGCAGTCAGAAGCACCTCCTTCTCTGGTATCCTTTGCCGTCTCATCAGAAGGCACAGAGCAGGGAGAAGATCCACGCT
CGGAAAAAGATCACAGCAGACCTCACAAGCACCGAGCGCGGCATGCACGGCTCAGGAGGAGTGAAAGCCTGTCAGAAAAACAAGTGAAGG
AAGCAAAATCTAAATGCAAAAGCATTGCCCTTCTTCTAACGGATGCTCCCAACCCCAACTCCAAGGGGGTGTTGATGTTTAAGAAGCGAC
GTCGGAGGGCCAGGAAATACACCCTAGTTAGCTACGGTACTGGCGAGCTTGAGCGAGAGGCGGACGAGGAGGAAGAAGGTGACAAGGAGG
ATACATGTGAAGTAGCATTTCTTGGTGCAAGCGAATCAGAGGTGGATGAAGAGTTATTGTCTGACGTTGACGACAACACACAAGTTGTGA
ACTTTGACTGGGATTCTGGACTGGTGGACATTGAAAAGAAACTGAACAGAGGGGACAAGATGGAGATGTTACCAGACACCACAGGCAAGG
GAGCCCTCATGTTTGCCAAGAGGAGGGAGAGAATGGATCAGATCACAGCCCAAAAAGAAGAGGACAAGGTAGGTGGAACGCCAAGCAGAG
AACAAGATGCTGCCCAGACCGATGGCCTGAGAACCACGACTTCTTACCAAAGAAAGGAGGAAGAGTCGGTAAGAACGCAGAGCTCTGTGA
GCAAAAGCTACATCGAGGTGAGTCATGGTCTTGGCCATGTTCCCCAACAGAATGGCTTCAGTGGGACATCTGAGACAGCAAACATCCAGA
GGATGGTCCCCATGAATAGAACGGCCAAACCCTTCCCAGGGTCTGTGAATCAGCCAGCTACCCCCTTCTCGCCAACCCGAAACATGACGA
GTCCCATTGCTGACTTTCCTGCACCTCCACCTTACTCTGCAGTCACTCCTCCCCCTGACGCCTTCTCCAGAGGGGTTTCAAGTCCGATTG
CTGGCCCAGCACAGCCCCCTCCATGGCCCCAGCCTGCCCCGTGGTCCCAGCCAGCCTTTTACGATTCGTCTGAGCGAATAGCTTCCCGAG
ATGAGAGGATCTCAGTGCCAGCAAAAAGAACAGGAATATTGCAGGAGGCCAAAAGGAGAAGCACGACAAAACCCATGTTTACTTTTAAAG
AGCCCAAAGTAAGCCCAAATCCTGAACTCTTGTCACTCCTTCAAAATTCAGAAGGCAAACGGGGCACTGGAGCTGGAGGTGATTCCGGAC
CGGAAGAAGACTACCTCAGCTTGGGGGCAGAGGCTTGTAATTTCATGCAAAGCTCCTCTGCCAAACAAAAGACCCCTCCTCCTGTTGCTC
CAAAACCTGCAGTCAAGTCCTCATCCTCCCAACCAGTAACTCCAGTTTCCCCAGTCTGGTCTCCAGGAGTGGCTCCCACCCAACCTCCTG
CCTTCCCCACATCCAACCCATCAAAGGGCACCGTTGTCTCCTCCATCAAAATAGCCCAGCCTTCTTACCCTCCTGCCCGGCCTGCAAGTA
CTTTGAACGTGGCTGGTCCCTTCAAAGGACCACAAGCAGCAGTAGCCAGTCAGAATTACACACCCAAACCAACAGTTTCCACACCAACAG
TCAATGCTGTTCAGCCTGGTGCAGTGGGACCATCCAATGAGCTTCCAGGAATGAGTGGGAGAGGAGCTCAGCTCTTTGCTAAAAGGCAGT
CGAGAATGGAGAAGTATGTGGTCGATTCAGACACGGTGCAGGCCCACGCTGCTCGAGCTCAGTCTCCCACTCCATCTCTCCCGGCCAGTT
GGAAGTACTCCTCCAATGTCCGAGCACCTCCTCCTGTGGCCTATAATCCTATCCACTCGCCGTCTTACCCACTGGCTGCTCTCAAGTCTC
AGCCATCAGCTGCACAGCCCTCCAAAATGGGCAAGAAAAAGGGAAAGAAACCCCTCAATGCATTAGATGTCATGAAGCACCAACCGTATC
AGCTCAATGCATCCTTGTTTACTTTCCAACCTCCAGATGCAAAGGATGGCCTCCCCCAGAAGTCATCAGTCAAGGTCAATTCAGCCCTGG
CCATGAAGCAAGCTCTTCCTCCCCGGCCAGTGAATGCTGCCTCACCTACGAATGTGCAGGCTTCGTCAGTGTACTCGGTACCAGCCTATA
CCTCTCCTCCTTCCTTCTTTGCAGAGGCCTCCTCACCAGTCAGTGCATCCCCAGTGCCTGTGGGCATTCCCACCTCGCCAAAGCAAGAAT
CAGCCTCATCATCTTATTTTGTGGCACCAAGGCCAAAGTTCTCAGCCAAGAAAAGTGGTGTCACAATTCAGGAGAGTGGGCGCTCCCTTT
CTCTTCCTGGAAGATCAGTCCCACCCCCCATTTCTACATCTCCTTGGGTATACCAGCCTACTTATAGTTACTCTAGTAAACCAACCGATG
GACTAGAGAAAGCAAACAAGAGACCAACTCCTTGGGAAGCAGCAGCAAAGTCTCCTCTCGGTCTAGTGGATGATGCTTTCCAACCCAGAA
ACATCCAGGAATCCATTGTGGCAAATGTGGTTTCAGCAGCTCGGAGGAAGGTGCTTCCAGGGCCTCCAGAGGATTGGAATGAAAGACTGT
CCTATATTCCTCAAACCCAGAAGGCCTATATGGGCTCATGTGGAAGGCAAGAGTATAATGTCACAGCCAATAATAATATGTCCACCACCT
CCCAATATGGTTCACAGTTGCCATATGCATATTATAGGCAGGCTTCAAGAAATGATTCTGCAATCATGTCCATGGAAACCAGGTCTGATT
ACTGTCTTCCAGTAGCTGATTACAACTACAACCCACACCCAAGGGGATGGAGACGCCAAACATGAAAGTTAGAAGAACGGATCATGTGCC
AACTGTAGTTTTTTAAAAAAAACGCTCCTTTGTAGGGTTTTAAACTTTTCTAATAGATTTAGATTCACTTTTGGTCTTGGCTTGTTCTCA
TAAGTCATTTATCTAAGTTTGTGTTTCTGTGTGTGTGTGTGTGTGTGTATGTATGTGAATATACACACACACACACACACAGGTGAGTGT
GAATACTTCCTTGTTGGCTGATCCATAGAGCATTACTTGGAAGAAAATTTCACTATTTGCATTGATGTGCTGGCATTTATATGTAATTCA
TAATTTTGATTCCATTAATAGGTAGTCTATGCAACAAACTCTACTCAATTAAAGTAAAACTAAGTATTTCTTCATTGTACCTTAGTCCAG
GAAGAAATTAATGGAATATGGTGTGCTAATTATCACTACCTATAACATGAGGAATATAACATTGCAGAAATTTCTCATAGGGGCATGCCA
GTGAGCAATTACTTTATAAAAATATTTTCCTTGGTGTTAAGTATTTCTCTGCAACTTTTTTTTTTTTTTTTTTTTTTTTTTGAGATGGAG
TCTTGCTCTGTCCCACCCAGTCTGGAGTGCAATGGTGCGATCTTGGCTCACTGCAACCTGCGCCTCCTGGGTTCAAGCAATTCTCCTGCC
TCAGCCTCCTGAGTAGCTGGGATTACAGGCATGAACCACCACACCTGGATAATTTTTGTATTTTTAGTAGACACAAAGTTTCACCATGTT
GGTCAGACTGGTCTTGAACTCCTGACCTCGTGATCTGCCCGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCACACCTG
GCCTTTCTGCAACATTTTTTTAAAAAAATCTAATAAATCTTAGATTTTTAAAAAAGAATTAAAATGTGGGAGTTCTCAGAAAGAAATAAA
CACATGAGAATAAGATTATTACACATTTTGGAAGGACTTTTGAGGAATGATGTGATGTGTAGAGAATAGAAAGATTTAGATATATGCCTG
TGACAGGAATAGATTCTGGGTTCAGGGGTCCCCATCTGTCAAATGAGAAGATTGGATTATCTAATCTTTTAGATCCTTAACAACTCTGAT
ATTCTGAGATTCTCTCATTTGTAGAATGCCCGCTGATGCATTGTTTATTTTTTTTGCTCATAATATAAATATCAGATTATGTTTAGGAGT
GGATTAGGTAATTAGTGTCACTACATGTATCATTAAAGGTCCTAAAAGGAATTGTTAGGCGGCAGGCTTTGTGTTACGTGTTACATGGAG
TGAGGGTAGATGTGAAGATTTAAAACGATTGATGGATTTAAGGAAGTGGTACATAAATATGTCTGTTATTATGCAATCGTAGGTCATGAT
AATTTATTCAGTTATAGAAAACATGCCACAGAAGCCTATGTAACAAGTGGTGCTTCTTTAGAAAGTTGTCATTAGAATGTTCTGAGGAAG
TTAAGCAGCTGCTTCATCAATCCCATGACACATGCCTTGTTAGCATGCCCATCAAATAATCAGATCAAACACCTGCTCCTTATTGCCATA
CCCACGAACTGTTAAATATAAAAAAATTCAAAGTATTTGACATCTTAAGCAAATATCCAGAATATTTTTAAGTAAAAAACCATCTTAAGT
ATTCAAAATTTCCTTGGTTTTTTAAAGGTGATAATTTTGCTTTGTGTTACTTTTTTGCTCTTGAATGTATCGTTATGATGGTCTCTTATA
ATCATGGTATCTTTCACAGAATAAAAATTAAAAATAATGCCAGGGTGCAAGTGACCAAGGCCTTATCTTGAAAGTTAAAAAAAAAAAGTA
AAGAAATCACAGTAAGTTCTATTAGTGATGATAGAACCAGATATAAAATTGTTCAGTGATGGAGAAAAGAAACGATAAATACTTTCCAAG
GTTATATTGTTAAATTATCTTAAATTATCAAGGTGTAAGATGTAATGATCCCAAGAGTTTTTATAGAATCCTAAAAAATAACGCCTGATG
TATAGATTAGTTAGCAAATTCTCAGAAATCCCCCACATAAAAGCCTTACTTTGTTCAAAATTTATTATAGTGGTTTAATCATTTTAGATT
TGAATGTTTTAAGATAGGAGAGACTTAGCAGAAAATACTTGGCTTGCCAGGGCCACGTTCTACTTCATTGCTTTCTTTTATAAGTGCAAG
GAGTTATTTCCATCAGTTGACATAGATATTATTCACTAAAATTTTCAGCAGACTCAAAATAGAGAGGAGACTTTAAACTTACATGTTAGC
ATAAAACAGACTTCTCTCTCATTGCATGCACTAGATCAATATTATCATCTGTATTAAGCTATCTGAATTTATTCGAGACATTAAGAAAAA
GACAGTACATGGTGGGAAAGCTGCACATTTCTCACAAGGAAAAAAACATTCTATATTTGTAGCAGAAATCAGTGGTTTGAAAAGTCATAC
TTTGCAGATATGAACCTGAAAATCAAAGTGCCATTGTTAAATCATCCTAAAGTGTACTGTGGGTATTCTCCAGCATACTTGAAAATGAAT
AAAGTTAGATTGCTCACATTGAAGCTAATGGTTGAGACAAGACACCTGCCAGAGTGAAGTTTGATTCCTATGGGTGAGAAGATGTAGATG
ACTATTGTTCTCACTAAAGTTCTAAAATAATAGCAAGTGTAGAGAAGAGCCGTTGCTTTGAAAATACATACCACATTTGTTATAAAGCAT
TTGTTTGTTAGTATCAATCACATAGGTAGAAAGAGTTTGAGTTTTACTGTGGATTAAAAAGCCTTCCCTAAAAAGAGAGCATGCCAGTCA
TAGAGACACTAATTTGGCACTTTTCCTCCTTCTTAGGTTTAAATGTTATACCAATGCATGTGTTTGAAATATCCATTAAGATGATTTAAA
ATTTGTCTTGTATTTTGAGTTTCTTAAATGCGTGGATTCTTGTTCATTTATCTCTGAATATGTCTCTTTTATATTTTGGCACAATTATAC
ACATTGGAAAGGGCCAACCTATTAGGGCTCAAGTATGTATATGCAAAAAAAAAAAGTTATATCAAACAGGCACAGTTATTACAACTAGAG
AGAAATTCCAGAAATATTTGTTTTTTTAAGAGAAAGTAAATTTTCACATTAGATTTCTATTCAAAGTACTAATATCTACATGGTCCACAC
TTTTCTATTTTAAAAAATTGTGTTCTCTTGTTAAATAGATTAACATTTCCACTTCTGTTTATCACAAAAGACTGTATTTGAAATATGCAT

>In-frame_ENST00000284073_ENST00000307142_TCGA-L3-A524-01A_MSI2_chr17_55478832_+_SYNPO2_chr4_119944585_length(amino acids)=1371AA_start in transcript=179_stop in transcript=4294
MGVGGRGGSDMEANGSQGTSGSANDSQHDPGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLG
QPHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKIRNQSKASGSGLCEGDEVVSINGNPCADLTYPEVI
KLMESITDSLQMLIKRPSSGISEALISENENKNLEHLTHGGYVESTTLQIRPATKTQCTEFFLAPVKTEVPLAENQRSGPDCAGSLKEET
GPSYQRAPQMPDSQRGRVAEELILREKVEAVQPGPVVELQLSLSQERHKGASGPLVALPGAEKSKSPDPDPNLSHDRIVHINSIPTNEKA
DPFLRSSKIIQISSGRELRVIQESEAGDAGLPRVEVILDCSDRQKTEGCRLQAGKECVDSPVEGGQSEAPPSLVSFAVSSEGTEQGEDPR
SEKDHSRPHKHRARHARLRRSESLSEKQVKEAKSKCKSIALLLTDAPNPNSKGVLMFKKRRRRARKYTLVSYGTGELEREADEEEEGDKE
DTCEVAFLGASESEVDEELLSDVDDNTQVVNFDWDSGLVDIEKKLNRGDKMEMLPDTTGKGALMFAKRRERMDQITAQKEEDKVGGTPSR
EQDAAQTDGLRTTTSYQRKEEESVRTQSSVSKSYIEVSHGLGHVPQQNGFSGTSETANIQRMVPMNRTAKPFPGSVNQPATPFSPTRNMT
SPIADFPAPPPYSAVTPPPDAFSRGVSSPIAGPAQPPPWPQPAPWSQPAFYDSSERIASRDERISVPAKRTGILQEAKRRSTTKPMFTFK
EPKVSPNPELLSLLQNSEGKRGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTPVSPVWSPGVAPTQPP
AFPTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNYTPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQ
SRMEKYVVDSDTVQAHAARAQSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLNALDVMKHQPY
QLNASLFTFQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNAASPTNVQASSVYSVPAYTSPPSFFAEASSPVSASPVPVGIPTSPKQE
SASSSYFVAPRPKFSAKKSGVTIQESGRSLSLPGRSVPPPISTSPWVYQPTYSYSSKPTDGLEKANKRPTPWEAAAKSPLGLVDDAFQPR
NIQESIVANVVSAARRKVLPGPPEDWNERLSYIPQTQKAYMGSCGRQEYNVTANNNMSTTSQYGSQLPYAYYRQASRNDSAIMSMETRSD

--------------------------------------------------------------
>In-frame_ENST00000284073_ENST00000448416_TCGA-L3-A524-01A_MSI2_chr17_55478832_+_SYNPO2_chr4_119944585_length(transcript)=1658nt_BP=614nt
CGGGGCTGAGCTAAGCCGAGCCCACGTGTGACGGCTCTCGCCGCTGCCCCGGCTCCGCCGCTCGCAGAGAGATTCGGAGGAGCCCGGGCG
GGGGGGAGGAGGAGGGGGAGGAGGGAGCGGAGATCTCGGGGCTCGGAGCCGGCCGCCGCTCCGCTCCGATCGCTGTGGGGCTTGGTTTTT
TGGGGGTGGGGGGGCGGGGGGGCTCAGATATGGAGGCAAATGGGAGCCAAGGCACCTCGGGCAGCGCCAACGACTCCCAGCACGACCCCG
GTAAAATGTTTATCGGTGGACTGAGCTGGCAGACCTCACCAGATAGCCTTAGAGACTATTTTAGCAAATTTGGAGAAATTAGAGAATGTA
TGGTCATGAGAGATCCCACTACGAAACGCTCCAGAGGCTTCGGTTTCGTCACGTTCGCAGACCCAGCAAGTGTAGATAAAGTATTAGGTC
AGCCCCACCATGAGTTAGATTCCAAGACGATTGACCCCAAAGTTGCATTTCCTCGTCGAGCGCAACCCAAGATGGTCACAAGAACAAAGA
AAATATTTGTAGGCGGGTTATCTGCGAACACAGTAGTGGAAGATGTAAAGCAATATTTCGAGCAGTTTGGCAAGATTCGAAATCAGAGCA
AAGCCTCTGGGTCTGGGCTCTGTGAGGGAGATGAAGTGGTTTCCATCAATGGCAACCCTTGTGCAGATCTCACCTACCCTGAAGTCATCA
AGCTCATGGAAAGCATAACAGACTCTCTCCAAATGCTCATCAAAAGGAGAGTGGGCGCTCCCTTTCTCTTCCTGGAAGATCAGTCCCACC
CCCCATTTCTACATCTCCTTGGGTATACCAGCCTACTTATAGTTACTCTAGTAAACCAACCGATGGACTAGAGAAAGCAAACAAGAGACC
AACTCCTTGGGAAGCAGCAGCAAAGTCTCCTCTCGGTCTAGTGGATGATGCTTTCCAACCCAGAAACATCCAGGAATCCATTGTGGCAAA
TGTGGTTTCAGCAGCTCGGAGGAAGGTGCTTCCAGGGCCTCCAGAGGATTGGAATGAAAGACTGTCCTATATTCCTCAAACCCAGAAGGC
CTATATGGGCTCATGTGGAAGGCAAGAGTATAATGTCACAGCCAATAATAATATGTCCACCACCTCCCAATATGGTTCACAGTTGCCATA
TGCATATTATAGGCAGGCTTCAAGAAATGATTCTGCAATCATGTCCATGGAAACCAGGTCTGATTACTGTCTTCCAGTAGCTGATTACAA
CTACAACCCACACCCAAGGGGATGGAGACGCCAAACATGAAAGTTAGAAGAACGGATCATGTGCCAACTGTAGTTTTTTAAAAAAAACGC
TCCTTTGTAGGGTTTTAAACTTTTCTAATAGATTTAGATTCACTTTTGGTCTTGGCTTGTTCTCATAAGTCATTTATCTAAGTTTGTGTT
TCTGTGTGTGTGTGTGTGTGTGTATGTATGTGAATATACACACACACACACACACAGGTGAGTGTGAATACTTCCTTGTTGGCTGATCCA
TAGAGCATTACTTGGAAGAAAATTTCACTATTTGCATTGATGTGCTGGCATTTATATGTAATTCATAATTTTGATTCCATTAATAGGTAG

>In-frame_ENST00000284073_ENST00000448416_TCGA-L3-A524-01A_MSI2_chr17_55478832_+_SYNPO2_chr4_119944585_length(amino acids)=233AA_start in transcript=179_stop in transcript=880
MGVGGRGGSDMEANGSQGTSGSANDSQHDPGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLG
QPHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKIRNQSKASGSGLCEGDEVVSINGNPCADLTYPEVI

--------------------------------------------------------------
>In-frame_ENST00000284073_ENST00000429713_TCGA-L3-A524-01A_MSI2_chr17_55478832_+_SYNPO2_chr4_119944585_length(transcript)=7569nt_BP=614nt
CGGGGCTGAGCTAAGCCGAGCCCACGTGTGACGGCTCTCGCCGCTGCCCCGGCTCCGCCGCTCGCAGAGAGATTCGGAGGAGCCCGGGCG
GGGGGGAGGAGGAGGGGGAGGAGGGAGCGGAGATCTCGGGGCTCGGAGCCGGCCGCCGCTCCGCTCCGATCGCTGTGGGGCTTGGTTTTT
TGGGGGTGGGGGGGCGGGGGGGCTCAGATATGGAGGCAAATGGGAGCCAAGGCACCTCGGGCAGCGCCAACGACTCCCAGCACGACCCCG
GTAAAATGTTTATCGGTGGACTGAGCTGGCAGACCTCACCAGATAGCCTTAGAGACTATTTTAGCAAATTTGGAGAAATTAGAGAATGTA
TGGTCATGAGAGATCCCACTACGAAACGCTCCAGAGGCTTCGGTTTCGTCACGTTCGCAGACCCAGCAAGTGTAGATAAAGTATTAGGTC
AGCCCCACCATGAGTTAGATTCCAAGACGATTGACCCCAAAGTTGCATTTCCTCGTCGAGCGCAACCCAAGATGGTCACAAGAACAAAGA
AAATATTTGTAGGCGGGTTATCTGCGAACACAGTAGTGGAAGATGTAAAGCAATATTTCGAGCAGTTTGGCAAGATTCGAAATCAGAGCA
AAGCCTCTGGGTCTGGGCTCTGTGAGGGAGATGAAGTGGTTTCCATCAATGGCAACCCTTGTGCAGATCTCACCTACCCTGAAGTCATCA
AGCTCATGGAAAGCATAACAGACTCTCTCCAAATGCTCATCAAAAGACCATCCAGTGGAATAAGTGAGGCTTTGATATCTGAAAATGAAA
ACAAAAACCTCGAGCATCTCACACATGGGGGTTATGTGGAAAGTACCACCCTGCAGATTCGACCGGCCACAAAGACCCAGTGCACAGAAT
TCTTCCTCGCCCCTGTCAAGACTGAAGTTCCCCTAGCTGAGAACCAAAGAAGTGGTCCCGACTGTGCAGGCAGCTTGAAAGAAGAAACAG
GCCCGAGCTACCAAAGGGCTCCCCAAATGCCTGACTCCCAAAGAGGACGCGTGGCAGAAGAGCTGATCTTAAGGGAGAAGGTAGAAGCGG
TACAGCCTGGGCCTGTGGTTGAGCTGCAACTGTCCCTTTCACAGGAGAGACATAAGGGCGCTAGTGGCCCTTTAGTGGCTCTCCCGGGAG
CTGAAAAATCTAAGTCTCCTGACCCAGACCCTAACTTGTCACATGACAGGATTGTCCACATAAATTCGATCCCTACTAATGAGAAAGCAG
ACCCTTTCCTGAGGTCCAGCAAGATAATCCAGATCTCCAGTGGCAGAGAGTTGAGAGTGATCCAGGAAAGTGAAGCAGGAGATGCGGGAC
TGCCCCGGGTGGAAGTGATCCTCGACTGCTCTGACAGGCAGAAGACAGAAGGGTGCAGGCTTCAGGCAGGAAAGGAGTGTGTGGATTCTC
CAGTGGAAGGAGGGCAGTCAGAAGCACCTCCTTCTCTGGTATCCTTTGCCGTCTCATCAGAAGGCACAGAGCAGGGAGAAGATCCACGCT
CGGAAAAAGATCACAGCAGACCTCACAAGCACCGAGCGCGGCATGCACGGCTCAGGAGGAGTGAAAGCCTGTCAGAAAAACAAGTGAAGG
AAGCAAAATCTAAATGCAAAAGCATTGCCCTTCTTCTAACGGATGCTCCCAACCCCAACTCCAAGGGGGTGTTGATGTTTAAGAAGCGAC
GTCGGAGGGCCAGGAAATACACCCTAGTTAGCTACGGTACTGGCGAGCTTGAGCGAGAGGCGGACGAGGAGGAAGAAGGTGACAAGGAGG
ATACATGTGAAGTAGCATTTCTTGGTGCAAGCGAATCAGAGGTGGATGAAGAGTTATTGTCTGACGTTGACGACAACACACAAGTTGTGA
ACTTTGACTGGGATTCTGGACTGGTGGACATTGAAAAGAAACTGAACAGAGGGGACAAGATGGAGATGTTACCAGACACCACAGGCAAGG
GAGCCCTCATGTTTGCCAAGAGGAGGGAGAGAATGGATCAGATCACAGCCCAAAAAGAAGAGGACAAGGTAGGTGGAACGCCAAGCAGAG
AACAAGATGCTGCCCAGACCGATGGCCTGAGAACCACGACTTCTTACCAAAGAAAGGAGGAAGAGTCGGTAAGAACGCAGAGCTCTGTGA
GCAAAAGCTACATCGAGGTGAGTCATGGTCTTGGCCATGTTCCCCAACAGAATGGCTTCAGTGGGACATCTGAGACAGCAAACATCCAGA
GGATGGTCCCCATGAATAGAACGGCCAAACCCTTCCCAGGGTCTGTGAATCAGCCAGCTACCCCCTTCTCGCCAACCCGAAACATGACGA
GTCCCATTGCTGACTTTCCTGCACCTCCACCTTACTCTGCAGTCACTCCTCCCCCTGACGCCTTCTCCAGAGGGGTTTCAAGTCCGATTG
CTGGCCCAGCACAGCCCCCTCCATGGCCCCAGCCTGCCCCGTGGTCCCAGCCAGCCTTTTACGATTCGTCTGAGCGAATAGCTTCCCGAG
ATGAGAGGATCTCAGTGCCAGCAAAAAGAACAGGAATATTGCAGGAGGCCAAAAGGAGAAGCACGACAAAACCCATGTTTACTTTTAAAG
AGCCCAAAGTAAGCCCAAATCCTGAACTCTTGTCACTCCTTCAAAATTCAGAAGGCAAACGGGGCACTGGAGCTGGAGGTGATTCCGGAC
CGGAAGAAGACTACCTCAGCTTGGGGGCAGAGGCTTGTAATTTCATGCAAAGCTCCTCTGCCAAACAAAAGACCCCTCCTCCTGTTGCTC
CAAAACCTGCAGTCAAGTCCTCATCCTCCCAACCAGTAACTCCAGTTTCCCCAGTCTGGTCTCCAGGAGTGGCTCCCACCCAACCTCCTG
CCTTCCCCACATCCAACCCATCAAAGGGCACCGTTGTCTCCTCCATCAAAATAGCCCAGCCTTCTTACCCTCCTGCCCGGCCTGCAAGTA
CTTTGAACGTGGCTGGTCCCTTCAAAGGACCACAAGCAGCAGTAGCCAGTCAGAATTACACACCCAAACCAACAGTTTCCACACCAACAG
TCAATGCTGTTCAGCCTGGTGCAGTGGGACCATCCAATGAGCTTCCAGGAATGAGTGGGAGAGGAGCTCAGCTCTTTGCTAAAAGGCAGT
CGAGAATGGAGAAGTATGTGGTCGATTCAGACACGGTGCAGGCCCACGCTGCTCGAGCTCAGTCTCCCACTCCATCTCTCCCGGCCAGTT
GGAAGTACTCCTCCAATGTCCGAGCACCTCCTCCTGTGGCCTATAATCCTATCCACTCGCCGTCTTACCCACTGGCTGCTCTCAAGTCTC
AGCCATCAGCTGCACAGCCCTCCAAAATGGGCAAGAAAAAGGGAAAGAAACCCCTCAATGCATTAGATGTCATGAAGCACCAACCGTATC
AGCTCAATGCATCCTTGTTTACTTTCCAACCTCCAGATGCAAAGGATGGCCTCCCCCAGAAGTCATCAGTCAAGGTCAATTCAGCCCTGG
CCATGAAGCAAGCTCTTCCTCCCCGGCCAGTGAATGCTGCCTCACCTACGAATGTGCAGGCTTCGTCAGTGTACTCGGTACCAGCCTATA
CCTCTCCTCCTTCCTTCTTTGCAGAGGCCTCCTCACCAGTCAGTGCATCCCCAGTGCCTGTGGGCATTCCCACCTCGCCAAAGCAAGAAT
CAGCCTCATCATCTTATTTTGTGGCACCAAGGCCAAAGTTCTCAGCCAAGAAAAGTGGTGTCACAATTCAGGTGTGGAAACCATCTGTTG
TGGAAGAGTAATCTTGTAGCTGAAGCTGAGTGTCCACTTTGCTTGAAATGAATTGTTTGCAGTGTTTCTTGAGTCCCTGAGAATGCCTAG
CAAAGTCCTCAACTTACTTAATTTCAGATATGTCACCTCCTAATCTGGGTCCAAGGAGTATAATATTTTTAATGAGTCAAAAATCCAACT
CAGATTGACCTAAAATATATTTATCTTCTTTGCACACTTAAAAAATCCAGGAGCACCCCAAAATAGACATGTACCGTTATATTAAGTAAG
CAGGAGACTTAGGATTTGTGCTGTAGCCACAAGAAAGACAGTGATCAGTGATATCAAACATCAGGAATCAGCCTTTATGTAACATAACAG
CTGTCCTCCTATGGTGAAAGGTTCAAATGTAGTGAAGGTATAACCTATATTGACTGAGATTTCCCTTTTAGGTAGTGCCTTATCTCTATT
ACTAGTGTTAAAGGAATAAGGAATCTATGAAGGACAGGGAGCAGCTCTGGTCTGTCAATCTCAGCCACCTGTTTGATATCACAGAGAAGA
TACTCGGAGGATTGTTGGAATGTATATAGTTTAGTAAGAAGTGGGTAAGAAAGAGGGTCTTAATTACTGAGCACTTATTATGTATTAGGT
TCTTTGCCAGATGTTTTTACATATATAAACTCATTTCAGAAAACTTATTTAAAGTAAATGGGGCCGGGTATGGTGGTTCATGCCTGGAAT
CCTAGCACTTTGGGAGGCTGAGGTAGGAGGACTGCTTGAGGCCGGGAGTTGGAGACCAGCCTGAGCAACATAGTGAGACCCTGTCTCAAT
AATAATAATAATAATAGTAATAATGAAGTAAATGGGATAAGGAAAGAAGGATAATTATCTTTAAAGGTTGATTCCCACCCTCCCTCCCCA
GTTACTTAAGGAACTAAGTGAGTACATCTCCAGTTGCCCATGAAAGCATAAGTTTGTTTTCCTCAGCTGAGGCAAGTGGTAGAGTATACA
GGATAACGAAGTAACATGTAAAAGGCAGGACGCACATAAAGGTGTACATGGCTATTGTTTCACCTGGAGAAACCACATGATTGGGACCTG
AAGGTTTACTGACTGACTACAGGGGCTGATTGTGAAGCACGAGGAACCCCATGTGTGTGGAGACTGTAGGGTGAGAGCACACAATTATTA
GCATCATTTCTGAGTGATCTCACAGATTTTTTTTCTTGTGTTTGCTTTGCTTTTTGACAACTGCTTCTCCCACGTTCCTTGCAATTCTAT
TCTCTCACCTTCACTTTACTATTTGTATTCGATGGACCAGGATAATTCAGGCAAGGTTACCTTGTAAACTTTAATTGGCCACACACCATG
TTGTCACCCAGCTGGCTATGAAGTGAATAATGGTACTGAAAGTAAACCTGAAGACCTTTCTCAGATCTATTTTAAGTCTGAGTCTGACCA
ACCATGGAAAATATTCGACATGAATTAATGTAGAGAACTATAAAGCATTTATGACAGCTCCAAGAAAAATCATCTACTCTATGCAGGAGA
TATGTTTAGAGACCTCTCAGAAAAACTTGCCTGGTTTGAGGGTACACAGTACCATTTTAATCTTCTGAAAATATCTGTATTCCTGCTCTT
TTTCTGCTGTCACTGTCAATCTGCTATATTTTTCACTATCCTATTAAAATATTACTGTCTCCTTTATCTGTTCAATGTCCATATTTTAAA
AAAATCTTCCTTGTATGAGCTATTCTGATCTAAATAATTTCTCTGATATTTCTCTATATGGCTCCCACAACAATTTCATTGTTGTTAGCA
TATCTATTTCTCCATACATTGTAAAACTGTAATCCTTAGGTATTTCTAAAACATAAAGAGGAGAATTAAGTCAGCTGCAGAACAATGGGG
CTGATTCTTCTGCTTTTTCTCTGGAAAATCTTTCATTGCTTTTGGTGGAAATTTACCTAGAGGTTACAACCACAGGATGTAGCTTGGTCT
CTTATTTGCCTTTTTGGGAAACCAATTAAGATTAATACAGGATAAAGGAAAAAAGCAATCTATTCATTATATAACACAGTTGTTTGTATT
ACTTGTTCCCTGCAAAGGAAATCTGTTGAATGCTTGCATTTTGAATTCTTTTCTAATAGAACAACCAAAAAAGGCTTCTTATGGTGCAGC
AGGAAAAAAGATCATTTTTATAGCTTTGCATTCTTAACATAGCATTTAAAGAGCGGCATGAATTAGAGGAAAGACATGGAACACACAGGT
AGTCGGTTTGAGATCATCGGCTTAAAAGTATCCTAGGATGGTAATGACCCAGAAGTATTTCCAGTTGTCTAGTGGTGTGGTATGCAGGAA
TGAGAAGTGTTTTCTTTCCATTTCCTGTTGGACAGGTGGCAATCTTAGCAGAGCCACTATTTGGAGTTGATAACTAAAGATGCAAATAAC
ATGACTATGCCTTCTGGTCATCCTAGGACTATTTGGAGTTCTCCAAAACCTTGTAAGAGGCATGTCAGGCATGCAGTAAAAGCATCTACA
ACTTCAGCTGGGCACTGGCAGCATAGGTCTCATCTTGGACCATACAGTCCCACTTTATAGAAGAGGGTGGAAGTTCTCCAAAACAATATC
CACAACAAAGTCTGACCTCACTCTGAGGGAGATGGGAAGTGGGAGGAAGAAGGACTAACCAGCTCCCTGGAGTAAGAGGAATTTGCTTTC
CCTGTCTGCCCACCAGGGGCTATATGTGCCACCTTTCAGGTTGGGGCCAAGGAAGTGATGTCAGTGTGACAGAAGGGAGAGTTAGACCTC
CAGACGTCAGCCTCCCTCCCATGGGGTACATTTTCAATCTGAGTGTTGTTGCCTTAGCTGTGTTGGTATTAGCTTGATTGGTTGGTCCGC
TGGTTATGAGGTGTAGGGAGGCAGTTTTTGTTTAGTTTTTAGGACTTTGCCTCTTCCTTTGTCCTTAGCATAATTTCTAGGCAGAGCATC
CACGAAGTCGGTTTTCATTGCCAGCTCAAGAGCGACAATCATTTACGAGTTCCTATGTTATGTTAGGTGCCTTATGTATATTATCCCAAA
TCCACTGCATGGTTTAAATACAGGCACTGGAATATAAATGAAAAAGGTCATTACAGTCACTGACTTTCTGCAGGACCTTAAACATTTCTC
TTTCCACAAGTTTCCCCTTAATCATGTGTCAAACCTCTCTTCCTGACGGGAATGTTGTGCTATAATGAATCTGCATAACGCTTGGGATTC
TAGGAGGAAGGAAGGTTCCATGGACATGTAAGTACAGCATATTCCCCTCAGTCTTCTAGGAGGGCAGAGTGAATCCCAGAACTGGTAAGA
TTGGGAATCTGAGCATTGCCACTTTAATCTTAGAATATTTATCATTTTGACACATCCTGTTTTTTAGAGAGGAAAACAAACACAGTTTCT
GCATTGGTAGTGTAAAGCATACCTTGTTAGGAACGTGTTTTGTAAGACACATTTGGGTTGTCACTCTAGAGCATGTCAAACTTTGTACTT
CAAAATATATTTAGTATGATTGTTAGTGGTAACATATATCAAGGCTTTGAATTAACTGTTTTATTTAATTTTCACAAGAAGCACTTATTT
TAGCCATAGGAAAACCAATCTGAGCTACAAATAGTTCTTTAAAATAAGCCCAGGTTATTTAGCTATTCTAGAAAGTGCCGACTTCTTTCA
AGAAGCAGGCATTGTAGGACAGCTGAGAATTATCACATAGCCTAAATTCTAGCCTGGCAGCAAGAGTCACATCTGAGATGTCCAAAAAAA

>In-frame_ENST00000284073_ENST00000429713_TCGA-L3-A524-01A_MSI2_chr17_55478832_+_SYNPO2_chr4_119944585_length(amino acids)=1203AA_start in transcript=179_stop in transcript=3790
MGVGGRGGSDMEANGSQGTSGSANDSQHDPGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLG
QPHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKIRNQSKASGSGLCEGDEVVSINGNPCADLTYPEVI
KLMESITDSLQMLIKRPSSGISEALISENENKNLEHLTHGGYVESTTLQIRPATKTQCTEFFLAPVKTEVPLAENQRSGPDCAGSLKEET
GPSYQRAPQMPDSQRGRVAEELILREKVEAVQPGPVVELQLSLSQERHKGASGPLVALPGAEKSKSPDPDPNLSHDRIVHINSIPTNEKA
DPFLRSSKIIQISSGRELRVIQESEAGDAGLPRVEVILDCSDRQKTEGCRLQAGKECVDSPVEGGQSEAPPSLVSFAVSSEGTEQGEDPR
SEKDHSRPHKHRARHARLRRSESLSEKQVKEAKSKCKSIALLLTDAPNPNSKGVLMFKKRRRRARKYTLVSYGTGELEREADEEEEGDKE
DTCEVAFLGASESEVDEELLSDVDDNTQVVNFDWDSGLVDIEKKLNRGDKMEMLPDTTGKGALMFAKRRERMDQITAQKEEDKVGGTPSR
EQDAAQTDGLRTTTSYQRKEEESVRTQSSVSKSYIEVSHGLGHVPQQNGFSGTSETANIQRMVPMNRTAKPFPGSVNQPATPFSPTRNMT
SPIADFPAPPPYSAVTPPPDAFSRGVSSPIAGPAQPPPWPQPAPWSQPAFYDSSERIASRDERISVPAKRTGILQEAKRRSTTKPMFTFK
EPKVSPNPELLSLLQNSEGKRGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTPVSPVWSPGVAPTQPP
AFPTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNYTPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQ
SRMEKYVVDSDTVQAHAARAQSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLNALDVMKHQPY
QLNASLFTFQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNAASPTNVQASSVYSVPAYTSPPSFFAEASSPVSASPVPVGIPTSPKQE

--------------------------------------------------------------
>In-frame_ENST00000284073_ENST00000434046_TCGA-L3-A524-01A_MSI2_chr17_55478832_+_SYNPO2_chr4_119944585_length(transcript)=4033nt_BP=614nt
CGGGGCTGAGCTAAGCCGAGCCCACGTGTGACGGCTCTCGCCGCTGCCCCGGCTCCGCCGCTCGCAGAGAGATTCGGAGGAGCCCGGGCG
GGGGGGAGGAGGAGGGGGAGGAGGGAGCGGAGATCTCGGGGCTCGGAGCCGGCCGCCGCTCCGCTCCGATCGCTGTGGGGCTTGGTTTTT
TGGGGGTGGGGGGGCGGGGGGGCTCAGATATGGAGGCAAATGGGAGCCAAGGCACCTCGGGCAGCGCCAACGACTCCCAGCACGACCCCG
GTAAAATGTTTATCGGTGGACTGAGCTGGCAGACCTCACCAGATAGCCTTAGAGACTATTTTAGCAAATTTGGAGAAATTAGAGAATGTA
TGGTCATGAGAGATCCCACTACGAAACGCTCCAGAGGCTTCGGTTTCGTCACGTTCGCAGACCCAGCAAGTGTAGATAAAGTATTAGGTC
AGCCCCACCATGAGTTAGATTCCAAGACGATTGACCCCAAAGTTGCATTTCCTCGTCGAGCGCAACCCAAGATGGTCACAAGAACAAAGA
AAATATTTGTAGGCGGGTTATCTGCGAACACAGTAGTGGAAGATGTAAAGCAATATTTCGAGCAGTTTGGCAAGATTCGAAATCAGAGCA
AAGCCTCTGGGTCTGGGCTCTGTGAGGGAGATGAAGTGGTTTCCATCAATGGCAACCCTTGTGCAGATCTCACCTACCCTGAAGTCATCA
AGCTCATGGAAAGCATAACAGACTCTCTCCAAATGCTCATCAAAAGACCATCCAGTGGAATAAGTGAGGCTTTGATATCTGAAAATGAAA
ACAAAAACCTCGAGCATCTCACACATGGGGGTTATGTGGAAAGTACCACCCTGCAGATTCGACCGGCCACAAAGACCCAGTGCACAGAAT
TCTTCCTCGCCCCTGTCAAGACTGAAGTTCCCCTAGCTGAGAACCAAAGAAGTGGTCCCGACTGTGCAGGCAGCTTGAAAGAAGAAACAG
GCCCGAGCTACCAAAGGGCTCCCCAAATGCCTGACTCCCAAAGAGGACGCGTGGCAGAAGAGCTGATCTTAAGGGAGAAGGTAGAAGCGG
TACAGCCTGGGCCTGTGGTTGAGCTGCAACTGTCCCTTTCACAGGAGAGACATAAGGGCGCTAGTGGCCCTTTAGTGGCTCTCCCGGGAG
CTGAAAAATCTAAGTCTCCTGACCCAGACCCTAACTTGTCACATGACAGGATTGTCCACATAAATTCGATCCCTACTAATGAGAAAGCAG
ACCCTTTCCTGAGGTCCAGCAAGATAATCCAGATCTCCAGTGGCAGAGAGTTGAGAGTGATCCAGGAAAGTGAAGCAGGAGATGCGGGAC
TGCCCCGGGTGGAAGTGATCCTCGACTGCTCTGACAGGCAGAAGACAGAAGGGTGCAGGCTTCAGGCAGGAAAGGAGTGTGTGGATTCTC
CAGTGGAAGGAGGGCAGTCAGAAGCACCTCCTTCTCTGGTATCCTTTGCCGTCTCATCAGAAGGCACAGAGCAGGGAGAAGATCCACGCT
CGGAAAAAGATCACAGCAGACCTCACAAGCACCGAGCGCGGCATGCACGGCTCAGGAGGAGTGAAAGCCTGTCAGAAAAACAAGTGAAGG
AAGCAAAATCTAAATGCAAAAGCATTGCCCTTCTTCTAACGGATGCTCCCAACCCCAACTCCAAGGGGGTGTTGATGTTTAAGAAGCGAC
GTCGGAGGGCCAGGAAATACACCCTAGTTAGCTACGGTACTGGCGAGCTTGAGCGAGAGGCGGACGAGGAGGAAGAAGGTGACAAGGAGG
ATACATGTGAAGTAGCATTTCTTGGTGCAAGCGAATCAGAGGTGGATGAAGAGTTATTGTCTGACGTTGACGACAACACACAAGTTGTGA
ACTTTGACTGGGATTCTGGACTGGTGGACATTGAAAAGAAACTGAACAGAGGGGACAAGATGGAGATGTTACCAGACACCACAGGCAAGG
GAGCCCTCATGTTTGCCAAGAGGAGGGAGAGAATGGATCAGATCACAGCCCAAAAAGAAGAGGACAAGGTAGGTGGAACGCCAAGCAGAG
AACAAGATGCTGCCCAGACCGATGGCCTGAGAACCACGACTTCTTACCAAAGAAAGGAGGAAGAGTCGGTAAGAACGCAGAGCTCTGTGA
GCAAAAGCTACATCGAGGTGAGTCATGGTCTTGGCCATGTTCCCCAACAGAATGGCTTCAGTGGGACATCTGAGACAGCAAACATCCAGA
GGATGGTCCCCATGAATAGAACGGCCAAACCCTTCCCAGGGTCTGTGAATCAGCCAGCTACCCCCTTCTCGCCAACCCGAAACATGACGA
GTCCCATTGCTGACTTTCCTGCACCTCCACCTTACTCTGCAGTCACTCCTCCCCCTGACGCCTTCTCCAGAGGGGTTTCAAGTCCGATTG
CTGGCCCAGCACAGCCCCCTCCATGGCCCCAGCCTGCCCCGTGGTCCCAGCCAGCCTTTTACGATTCGTCTGAGCGAATAGCTTCCCGAG
ATGAGAGGATCTCAGTGCCAGCAAAAAGAACAGGAATATTGCAGGAGGCCAAAAGGAGAAGCACGACAAAACCCATGTTTACTTTTAAAG
AGCCCAAAGTAAGCCCAAATCCTGAACTCTTGTCACTCCTTCAAAATTCAGAAGGCAAACGGGGCACTGGAGCTGGAGGTGATTCCGGAC
CGGAAGAAGACTACCTCAGCTTGGGGGCAGAGGCTTGTAATTTCATGCAAAGCTCCTCTGCCAAACAAAAGACCCCTCCTCCTGTTGCTC
CAAAACCTGCAGTCAAGTCCTCATCCTCCCAACCAGTAACTCCAGTTTCCCCAGTCTGGTCTCCAGGAGTGGCTCCCACCCAACCTCCTG
CCTTCCCCACATCCAACCCATCAAAGGGCACCGTTGTCTCCTCCATCAAAATAGCCCAGCCTTCTTACCCTCCTGCCCGGCCTGCAAGTA
CTTTGAACGTGGCTGGTCCCTTCAAAGGACCACAAGCAGCAGTAGCCAGTCAGAATTACACACCCAAACCAACAGTTTCCACACCAACAG
TCAATGCTGTTCAGCCTGGTGCAGTGGGACCATCCAATGAGCTTCCAGGAATGAGTGGGAGAGGAGCTCAGCTCTTTGCTAAAAGGCAGT
CGAGAATGGAGAAGTATGTGGTCGATTCAGACACGGTGCAGGCCCACGCTGCTCGAGCTCAGTCTCCCACTCCATCTCTCCCGGCCAGTT
GGAAGTACTCCTCCAATGTCCGAGCACCTCCTCCTGTGGCCTATAATCCTATCCACTCGCCGTCTTACCCACTGGCTGCTCTCAAGTCTC
AGCCATCAGCTGCACAGCCCTCCAAAATGGGCAAGAAAAAGGGAAAGAAACCCCTCAATGCATTAGATGTCATGAAGCACCAACCGTATC
AGCTCAATGCATCCTTGTTTACTTTCCAACCTCCAGATGCAAAGGATGGCCTCCCCCAGAAGTCATCAGTCAAGGTCAATTCAGCCCTGG
CCATGAAGCAAGCTCTTCCTCCCCGGCCAGTGAATGCTGCCTCACCTACGAATGTGCAGGCTTCGTCAGTGTACTCGGTACCAGCCTATA
CCTCTCCTCCTTCCTTCTTTGCAGAGGCCTCCTCACCAGTCAGTGCATCCCCAGTGCCTGTGGGCATTCCCACCTCGCCAAAGCAAGAAT
CAGCCTCATCATCTTATTTTGTGGCACCAAGGCCAAAGTTCTCAGCCAAGAAAAGTGGTGTCACAATTCAGGTGAAATGTAAATCTGGGA
TCCATAGTCAAGATATCATAAGGACCTACTTCCCAGCCTACCTTTCTTCCTCTACCTGATAATGATAATACTCAAAATAACAACATTCAA
AGGAAACACAAAGAAATCCTGCTTTCACATCTCCTATTTCTTGGGCTCCTTAATAACTACTGATGGTTTGTTCATGAAAAAAAATTTTTA

>In-frame_ENST00000284073_ENST00000434046_TCGA-L3-A524-01A_MSI2_chr17_55478832_+_SYNPO2_chr4_119944585_length(amino acids)=1219AA_start in transcript=179_stop in transcript=3838
MGVGGRGGSDMEANGSQGTSGSANDSQHDPGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLG
QPHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKIRNQSKASGSGLCEGDEVVSINGNPCADLTYPEVI
KLMESITDSLQMLIKRPSSGISEALISENENKNLEHLTHGGYVESTTLQIRPATKTQCTEFFLAPVKTEVPLAENQRSGPDCAGSLKEET
GPSYQRAPQMPDSQRGRVAEELILREKVEAVQPGPVVELQLSLSQERHKGASGPLVALPGAEKSKSPDPDPNLSHDRIVHINSIPTNEKA
DPFLRSSKIIQISSGRELRVIQESEAGDAGLPRVEVILDCSDRQKTEGCRLQAGKECVDSPVEGGQSEAPPSLVSFAVSSEGTEQGEDPR
SEKDHSRPHKHRARHARLRRSESLSEKQVKEAKSKCKSIALLLTDAPNPNSKGVLMFKKRRRRARKYTLVSYGTGELEREADEEEEGDKE
DTCEVAFLGASESEVDEELLSDVDDNTQVVNFDWDSGLVDIEKKLNRGDKMEMLPDTTGKGALMFAKRRERMDQITAQKEEDKVGGTPSR
EQDAAQTDGLRTTTSYQRKEEESVRTQSSVSKSYIEVSHGLGHVPQQNGFSGTSETANIQRMVPMNRTAKPFPGSVNQPATPFSPTRNMT
SPIADFPAPPPYSAVTPPPDAFSRGVSSPIAGPAQPPPWPQPAPWSQPAFYDSSERIASRDERISVPAKRTGILQEAKRRSTTKPMFTFK
EPKVSPNPELLSLLQNSEGKRGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTPVSPVWSPGVAPTQPP
AFPTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNYTPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQ
SRMEKYVVDSDTVQAHAARAQSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLNALDVMKHQPY
QLNASLFTFQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNAASPTNVQASSVYSVPAYTSPPSFFAEASSPVSASPVPVGIPTSPKQE

--------------------------------------------------------------
>In-frame_ENST00000322684_ENST00000307142_TCGA-L3-A524-01A_MSI2_chr17_55478832_+_SYNPO2_chr4_119944585_length(transcript)=7422nt_BP=428nt
GCTTTCCTTTTAGCTTTTGTAAGTTACACGTCAAAATGGCCGATCTGACATCGGTGCTCACTTCTGTTATGTTTTCTCCCTCTAGTAAAA
TGTTTATCGGTGGACTGAGCTGGCAGACCTCACCAGATAGCCTTAGAGACTATTTTAGCAAATTTGGAGAAATTAGAGAATGTATGGTCA
TGAGAGATCCCACTACGAAACGCTCCAGAGGCTTCGGTTTCGTCACGTTCGCAGACCCAGCAAGTGTAGATAAAGTATTAGGTCAGCCCC
ACCATGAGTTAGATTCCAAGACGATTGACCCCAAAGTTGCATTTCCTCGTCGAGCGCAACCCAAGATGGTCACAAGAACAAAGAAAATAT
TTGTAGGCGGGTTATCTGCGAACACAGTAGTGGAAGATGTAAAGCAATATTTCGAGCAGTTTGGCAAGATTCGAAATCAGAGCAAAGCCT
CTGGGTCTGGGCTCTGTGAGGGAGATGAAGTGGTTTCCATCAATGGCAACCCTTGTGCAGATCTCACCTACCCTGAAGTCATCAAGCTCA
TGGAAAGCATAACAGACTCTCTCCAAATGCTCATCAAAAGACCATCCAGTGGAATAAGTGAGGCTTTGATATCTGAAAATGAAAACAAAA
ACCTCGAGCATCTCACACATGGGGGTTATGTGGAAAGTACCACCCTGCAGATTCGACCGGCCACAAAGACCCAGTGCACAGAATTCTTCC
TCGCCCCTGTCAAGACTGAAGTTCCCCTAGCTGAGAACCAAAGAAGTGGTCCCGACTGTGCAGGCAGCTTGAAAGAAGAAACAGGCCCGA
GCTACCAAAGGGCTCCCCAAATGCCTGACTCCCAAAGAGGACGCGTGGCAGAAGAGCTGATCTTAAGGGAGAAGGTAGAAGCGGTACAGC
CTGGGCCTGTGGTTGAGCTGCAACTGTCCCTTTCACAGGAGAGACATAAGGGCGCTAGTGGCCCTTTAGTGGCTCTCCCGGGAGCTGAAA
AATCTAAGTCTCCTGACCCAGACCCTAACTTGTCACATGACAGGATTGTCCACATAAATTCGATCCCTACTAATGAGAAAGCAGACCCTT
TCCTGAGGTCCAGCAAGATAATCCAGATCTCCAGTGGCAGAGAGTTGAGAGTGATCCAGGAAAGTGAAGCAGGAGATGCGGGACTGCCCC
GGGTGGAAGTGATCCTCGACTGCTCTGACAGGCAGAAGACAGAAGGGTGCAGGCTTCAGGCAGGAAAGGAGTGTGTGGATTCTCCAGTGG
AAGGAGGGCAGTCAGAAGCACCTCCTTCTCTGGTATCCTTTGCCGTCTCATCAGAAGGCACAGAGCAGGGAGAAGATCCACGCTCGGAAA
AAGATCACAGCAGACCTCACAAGCACCGAGCGCGGCATGCACGGCTCAGGAGGAGTGAAAGCCTGTCAGAAAAACAAGTGAAGGAAGCAA
AATCTAAATGCAAAAGCATTGCCCTTCTTCTAACGGATGCTCCCAACCCCAACTCCAAGGGGGTGTTGATGTTTAAGAAGCGACGTCGGA
GGGCCAGGAAATACACCCTAGTTAGCTACGGTACTGGCGAGCTTGAGCGAGAGGCGGACGAGGAGGAAGAAGGTGACAAGGAGGATACAT
GTGAAGTAGCATTTCTTGGTGCAAGCGAATCAGAGGTGGATGAAGAGTTATTGTCTGACGTTGACGACAACACACAAGTTGTGAACTTTG
ACTGGGATTCTGGACTGGTGGACATTGAAAAGAAACTGAACAGAGGGGACAAGATGGAGATGTTACCAGACACCACAGGCAAGGGAGCCC
TCATGTTTGCCAAGAGGAGGGAGAGAATGGATCAGATCACAGCCCAAAAAGAAGAGGACAAGGTAGGTGGAACGCCAAGCAGAGAACAAG
ATGCTGCCCAGACCGATGGCCTGAGAACCACGACTTCTTACCAAAGAAAGGAGGAAGAGTCGGTAAGAACGCAGAGCTCTGTGAGCAAAA
GCTACATCGAGGTGAGTCATGGTCTTGGCCATGTTCCCCAACAGAATGGCTTCAGTGGGACATCTGAGACAGCAAACATCCAGAGGATGG
TCCCCATGAATAGAACGGCCAAACCCTTCCCAGGGTCTGTGAATCAGCCAGCTACCCCCTTCTCGCCAACCCGAAACATGACGAGTCCCA
TTGCTGACTTTCCTGCACCTCCACCTTACTCTGCAGTCACTCCTCCCCCTGACGCCTTCTCCAGAGGGGTTTCAAGTCCGATTGCTGGCC
CAGCACAGCCCCCTCCATGGCCCCAGCCTGCCCCGTGGTCCCAGCCAGCCTTTTACGATTCGTCTGAGCGAATAGCTTCCCGAGATGAGA
GGATCTCAGTGCCAGCAAAAAGAACAGGAATATTGCAGGAGGCCAAAAGGAGAAGCACGACAAAACCCATGTTTACTTTTAAAGAGCCCA
AAGTAAGCCCAAATCCTGAACTCTTGTCACTCCTTCAAAATTCAGAAGGCAAACGGGGCACTGGAGCTGGAGGTGATTCCGGACCGGAAG
AAGACTACCTCAGCTTGGGGGCAGAGGCTTGTAATTTCATGCAAAGCTCCTCTGCCAAACAAAAGACCCCTCCTCCTGTTGCTCCAAAAC
CTGCAGTCAAGTCCTCATCCTCCCAACCAGTAACTCCAGTTTCCCCAGTCTGGTCTCCAGGAGTGGCTCCCACCCAACCTCCTGCCTTCC
CCACATCCAACCCATCAAAGGGCACCGTTGTCTCCTCCATCAAAATAGCCCAGCCTTCTTACCCTCCTGCCCGGCCTGCAAGTACTTTGA
ACGTGGCTGGTCCCTTCAAAGGACCACAAGCAGCAGTAGCCAGTCAGAATTACACACCCAAACCAACAGTTTCCACACCAACAGTCAATG
CTGTTCAGCCTGGTGCAGTGGGACCATCCAATGAGCTTCCAGGAATGAGTGGGAGAGGAGCTCAGCTCTTTGCTAAAAGGCAGTCGAGAA
TGGAGAAGTATGTGGTCGATTCAGACACGGTGCAGGCCCACGCTGCTCGAGCTCAGTCTCCCACTCCATCTCTCCCGGCCAGTTGGAAGT
ACTCCTCCAATGTCCGAGCACCTCCTCCTGTGGCCTATAATCCTATCCACTCGCCGTCTTACCCACTGGCTGCTCTCAAGTCTCAGCCAT
CAGCTGCACAGCCCTCCAAAATGGGCAAGAAAAAGGGAAAGAAACCCCTCAATGCATTAGATGTCATGAAGCACCAACCGTATCAGCTCA
ATGCATCCTTGTTTACTTTCCAACCTCCAGATGCAAAGGATGGCCTCCCCCAGAAGTCATCAGTCAAGGTCAATTCAGCCCTGGCCATGA
AGCAAGCTCTTCCTCCCCGGCCAGTGAATGCTGCCTCACCTACGAATGTGCAGGCTTCGTCAGTGTACTCGGTACCAGCCTATACCTCTC
CTCCTTCCTTCTTTGCAGAGGCCTCCTCACCAGTCAGTGCATCCCCAGTGCCTGTGGGCATTCCCACCTCGCCAAAGCAAGAATCAGCCT
CATCATCTTATTTTGTGGCACCAAGGCCAAAGTTCTCAGCCAAGAAAAGTGGTGTCACAATTCAGGAGAGTGGGCGCTCCCTTTCTCTTC
CTGGAAGATCAGTCCCACCCCCCATTTCTACATCTCCTTGGGTATACCAGCCTACTTATAGTTACTCTAGTAAACCAACCGATGGACTAG
AGAAAGCAAACAAGAGACCAACTCCTTGGGAAGCAGCAGCAAAGTCTCCTCTCGGTCTAGTGGATGATGCTTTCCAACCCAGAAACATCC
AGGAATCCATTGTGGCAAATGTGGTTTCAGCAGCTCGGAGGAAGGTGCTTCCAGGGCCTCCAGAGGATTGGAATGAAAGACTGTCCTATA
TTCCTCAAACCCAGAAGGCCTATATGGGCTCATGTGGAAGGCAAGAGTATAATGTCACAGCCAATAATAATATGTCCACCACCTCCCAAT
ATGGTTCACAGTTGCCATATGCATATTATAGGCAGGCTTCAAGAAATGATTCTGCAATCATGTCCATGGAAACCAGGTCTGATTACTGTC
TTCCAGTAGCTGATTACAACTACAACCCACACCCAAGGGGATGGAGACGCCAAACATGAAAGTTAGAAGAACGGATCATGTGCCAACTGT
AGTTTTTTAAAAAAAACGCTCCTTTGTAGGGTTTTAAACTTTTCTAATAGATTTAGATTCACTTTTGGTCTTGGCTTGTTCTCATAAGTC
ATTTATCTAAGTTTGTGTTTCTGTGTGTGTGTGTGTGTGTGTATGTATGTGAATATACACACACACACACACACAGGTGAGTGTGAATAC
TTCCTTGTTGGCTGATCCATAGAGCATTACTTGGAAGAAAATTTCACTATTTGCATTGATGTGCTGGCATTTATATGTAATTCATAATTT
TGATTCCATTAATAGGTAGTCTATGCAACAAACTCTACTCAATTAAAGTAAAACTAAGTATTTCTTCATTGTACCTTAGTCCAGGAAGAA
ATTAATGGAATATGGTGTGCTAATTATCACTACCTATAACATGAGGAATATAACATTGCAGAAATTTCTCATAGGGGCATGCCAGTGAGC
AATTACTTTATAAAAATATTTTCCTTGGTGTTAAGTATTTCTCTGCAACTTTTTTTTTTTTTTTTTTTTTTTTTTGAGATGGAGTCTTGC
TCTGTCCCACCCAGTCTGGAGTGCAATGGTGCGATCTTGGCTCACTGCAACCTGCGCCTCCTGGGTTCAAGCAATTCTCCTGCCTCAGCC
TCCTGAGTAGCTGGGATTACAGGCATGAACCACCACACCTGGATAATTTTTGTATTTTTAGTAGACACAAAGTTTCACCATGTTGGTCAG
ACTGGTCTTGAACTCCTGACCTCGTGATCTGCCCGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCACACCTGGCCTTT
CTGCAACATTTTTTTAAAAAAATCTAATAAATCTTAGATTTTTAAAAAAGAATTAAAATGTGGGAGTTCTCAGAAAGAAATAAACACATG
AGAATAAGATTATTACACATTTTGGAAGGACTTTTGAGGAATGATGTGATGTGTAGAGAATAGAAAGATTTAGATATATGCCTGTGACAG
GAATAGATTCTGGGTTCAGGGGTCCCCATCTGTCAAATGAGAAGATTGGATTATCTAATCTTTTAGATCCTTAACAACTCTGATATTCTG
AGATTCTCTCATTTGTAGAATGCCCGCTGATGCATTGTTTATTTTTTTTGCTCATAATATAAATATCAGATTATGTTTAGGAGTGGATTA
GGTAATTAGTGTCACTACATGTATCATTAAAGGTCCTAAAAGGAATTGTTAGGCGGCAGGCTTTGTGTTACGTGTTACATGGAGTGAGGG
TAGATGTGAAGATTTAAAACGATTGATGGATTTAAGGAAGTGGTACATAAATATGTCTGTTATTATGCAATCGTAGGTCATGATAATTTA
TTCAGTTATAGAAAACATGCCACAGAAGCCTATGTAACAAGTGGTGCTTCTTTAGAAAGTTGTCATTAGAATGTTCTGAGGAAGTTAAGC
AGCTGCTTCATCAATCCCATGACACATGCCTTGTTAGCATGCCCATCAAATAATCAGATCAAACACCTGCTCCTTATTGCCATACCCACG
AACTGTTAAATATAAAAAAATTCAAAGTATTTGACATCTTAAGCAAATATCCAGAATATTTTTAAGTAAAAAACCATCTTAAGTATTCAA
AATTTCCTTGGTTTTTTAAAGGTGATAATTTTGCTTTGTGTTACTTTTTTGCTCTTGAATGTATCGTTATGATGGTCTCTTATAATCATG
GTATCTTTCACAGAATAAAAATTAAAAATAATGCCAGGGTGCAAGTGACCAAGGCCTTATCTTGAAAGTTAAAAAAAAAAAGTAAAGAAA
TCACAGTAAGTTCTATTAGTGATGATAGAACCAGATATAAAATTGTTCAGTGATGGAGAAAAGAAACGATAAATACTTTCCAAGGTTATA
TTGTTAAATTATCTTAAATTATCAAGGTGTAAGATGTAATGATCCCAAGAGTTTTTATAGAATCCTAAAAAATAACGCCTGATGTATAGA
TTAGTTAGCAAATTCTCAGAAATCCCCCACATAAAAGCCTTACTTTGTTCAAAATTTATTATAGTGGTTTAATCATTTTAGATTTGAATG
TTTTAAGATAGGAGAGACTTAGCAGAAAATACTTGGCTTGCCAGGGCCACGTTCTACTTCATTGCTTTCTTTTATAAGTGCAAGGAGTTA
TTTCCATCAGTTGACATAGATATTATTCACTAAAATTTTCAGCAGACTCAAAATAGAGAGGAGACTTTAAACTTACATGTTAGCATAAAA
CAGACTTCTCTCTCATTGCATGCACTAGATCAATATTATCATCTGTATTAAGCTATCTGAATTTATTCGAGACATTAAGAAAAAGACAGT
ACATGGTGGGAAAGCTGCACATTTCTCACAAGGAAAAAAACATTCTATATTTGTAGCAGAAATCAGTGGTTTGAAAAGTCATACTTTGCA
GATATGAACCTGAAAATCAAAGTGCCATTGTTAAATCATCCTAAAGTGTACTGTGGGTATTCTCCAGCATACTTGAAAATGAATAAAGTT
AGATTGCTCACATTGAAGCTAATGGTTGAGACAAGACACCTGCCAGAGTGAAGTTTGATTCCTATGGGTGAGAAGATGTAGATGACTATT
GTTCTCACTAAAGTTCTAAAATAATAGCAAGTGTAGAGAAGAGCCGTTGCTTTGAAAATACATACCACATTTGTTATAAAGCATTTGTTT
GTTAGTATCAATCACATAGGTAGAAAGAGTTTGAGTTTTACTGTGGATTAAAAAGCCTTCCCTAAAAAGAGAGCATGCCAGTCATAGAGA
CACTAATTTGGCACTTTTCCTCCTTCTTAGGTTTAAATGTTATACCAATGCATGTGTTTGAAATATCCATTAAGATGATTTAAAATTTGT
CTTGTATTTTGAGTTTCTTAAATGCGTGGATTCTTGTTCATTTATCTCTGAATATGTCTCTTTTATATTTTGGCACAATTATACACATTG
GAAAGGGCCAACCTATTAGGGCTCAAGTATGTATATGCAAAAAAAAAAAGTTATATCAAACAGGCACAGTTATTACAACTAGAGAGAAAT
TCCAGAAATATTTGTTTTTTTAAGAGAAAGTAAATTTTCACATTAGATTTCTATTCAAAGTACTAATATCTACATGGTCCACACTTTTCT
ATTTTAAAAAATTGTGTTCTCTTGTTAAATAGATTAACATTTCCACTTCTGTTTATCACAAAAGACTGTATTTGAAATATGCATACGGAA

>In-frame_ENST00000322684_ENST00000307142_TCGA-L3-A524-01A_MSI2_chr17_55478832_+_SYNPO2_chr4_119944585_length(amino acids)=1357AA_start in transcript=35_stop in transcript=4108
MADLTSVLTSVMFSPSSKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLGQPHHELDSKTIDPK
VAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKIRNQSKASGSGLCEGDEVVSINGNPCADLTYPEVIKLMESITDSLQMLI
KRPSSGISEALISENENKNLEHLTHGGYVESTTLQIRPATKTQCTEFFLAPVKTEVPLAENQRSGPDCAGSLKEETGPSYQRAPQMPDSQ
RGRVAEELILREKVEAVQPGPVVELQLSLSQERHKGASGPLVALPGAEKSKSPDPDPNLSHDRIVHINSIPTNEKADPFLRSSKIIQISS
GRELRVIQESEAGDAGLPRVEVILDCSDRQKTEGCRLQAGKECVDSPVEGGQSEAPPSLVSFAVSSEGTEQGEDPRSEKDHSRPHKHRAR
HARLRRSESLSEKQVKEAKSKCKSIALLLTDAPNPNSKGVLMFKKRRRRARKYTLVSYGTGELEREADEEEEGDKEDTCEVAFLGASESE
VDEELLSDVDDNTQVVNFDWDSGLVDIEKKLNRGDKMEMLPDTTGKGALMFAKRRERMDQITAQKEEDKVGGTPSREQDAAQTDGLRTTT
SYQRKEEESVRTQSSVSKSYIEVSHGLGHVPQQNGFSGTSETANIQRMVPMNRTAKPFPGSVNQPATPFSPTRNMTSPIADFPAPPPYSA
VTPPPDAFSRGVSSPIAGPAQPPPWPQPAPWSQPAFYDSSERIASRDERISVPAKRTGILQEAKRRSTTKPMFTFKEPKVSPNPELLSLL
QNSEGKRGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTPVSPVWSPGVAPTQPPAFPTSNPSKGTVVS
SIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNYTPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQ
AHAARAQSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLNALDVMKHQPYQLNASLFTFQPPDA
KDGLPQKSSVKVNSALAMKQALPPRPVNAASPTNVQASSVYSVPAYTSPPSFFAEASSPVSASPVPVGIPTSPKQESASSSYFVAPRPKF
SAKKSGVTIQESGRSLSLPGRSVPPPISTSPWVYQPTYSYSSKPTDGLEKANKRPTPWEAAAKSPLGLVDDAFQPRNIQESIVANVVSAA
RRKVLPGPPEDWNERLSYIPQTQKAYMGSCGRQEYNVTANNNMSTTSQYGSQLPYAYYRQASRNDSAIMSMETRSDYCLPVADYNYNPHP

--------------------------------------------------------------
>In-frame_ENST00000322684_ENST00000448416_TCGA-L3-A524-01A_MSI2_chr17_55478832_+_SYNPO2_chr4_119944585_length(transcript)=1472nt_BP=428nt
GCTTTCCTTTTAGCTTTTGTAAGTTACACGTCAAAATGGCCGATCTGACATCGGTGCTCACTTCTGTTATGTTTTCTCCCTCTAGTAAAA
TGTTTATCGGTGGACTGAGCTGGCAGACCTCACCAGATAGCCTTAGAGACTATTTTAGCAAATTTGGAGAAATTAGAGAATGTATGGTCA
TGAGAGATCCCACTACGAAACGCTCCAGAGGCTTCGGTTTCGTCACGTTCGCAGACCCAGCAAGTGTAGATAAAGTATTAGGTCAGCCCC
ACCATGAGTTAGATTCCAAGACGATTGACCCCAAAGTTGCATTTCCTCGTCGAGCGCAACCCAAGATGGTCACAAGAACAAAGAAAATAT
TTGTAGGCGGGTTATCTGCGAACACAGTAGTGGAAGATGTAAAGCAATATTTCGAGCAGTTTGGCAAGATTCGAAATCAGAGCAAAGCCT
CTGGGTCTGGGCTCTGTGAGGGAGATGAAGTGGTTTCCATCAATGGCAACCCTTGTGCAGATCTCACCTACCCTGAAGTCATCAAGCTCA
TGGAAAGCATAACAGACTCTCTCCAAATGCTCATCAAAAGGAGAGTGGGCGCTCCCTTTCTCTTCCTGGAAGATCAGTCCCACCCCCCAT
TTCTACATCTCCTTGGGTATACCAGCCTACTTATAGTTACTCTAGTAAACCAACCGATGGACTAGAGAAAGCAAACAAGAGACCAACTCC
TTGGGAAGCAGCAGCAAAGTCTCCTCTCGGTCTAGTGGATGATGCTTTCCAACCCAGAAACATCCAGGAATCCATTGTGGCAAATGTGGT
TTCAGCAGCTCGGAGGAAGGTGCTTCCAGGGCCTCCAGAGGATTGGAATGAAAGACTGTCCTATATTCCTCAAACCCAGAAGGCCTATAT
GGGCTCATGTGGAAGGCAAGAGTATAATGTCACAGCCAATAATAATATGTCCACCACCTCCCAATATGGTTCACAGTTGCCATATGCATA
TTATAGGCAGGCTTCAAGAAATGATTCTGCAATCATGTCCATGGAAACCAGGTCTGATTACTGTCTTCCAGTAGCTGATTACAACTACAA
CCCACACCCAAGGGGATGGAGACGCCAAACATGAAAGTTAGAAGAACGGATCATGTGCCAACTGTAGTTTTTTAAAAAAAACGCTCCTTT
GTAGGGTTTTAAACTTTTCTAATAGATTTAGATTCACTTTTGGTCTTGGCTTGTTCTCATAAGTCATTTATCTAAGTTTGTGTTTCTGTG
TGTGTGTGTGTGTGTGTATGTATGTGAATATACACACACACACACACACAGGTGAGTGTGAATACTTCCTTGTTGGCTGATCCATAGAGC
ATTACTTGGAAGAAAATTTCACTATTTGCATTGATGTGCTGGCATTTATATGTAATTCATAATTTTGATTCCATTAATAGGTAGTCTATG

>In-frame_ENST00000322684_ENST00000448416_TCGA-L3-A524-01A_MSI2_chr17_55478832_+_SYNPO2_chr4_119944585_length(amino acids)=219AA_start in transcript=35_stop in transcript=694
MADLTSVLTSVMFSPSSKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLGQPHHELDSKTIDPK
VAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKIRNQSKASGSGLCEGDEVVSINGNPCADLTYPEVIKLMESITDSLQMLI

--------------------------------------------------------------
>In-frame_ENST00000322684_ENST00000429713_TCGA-L3-A524-01A_MSI2_chr17_55478832_+_SYNPO2_chr4_119944585_length(transcript)=7383nt_BP=428nt
GCTTTCCTTTTAGCTTTTGTAAGTTACACGTCAAAATGGCCGATCTGACATCGGTGCTCACTTCTGTTATGTTTTCTCCCTCTAGTAAAA
TGTTTATCGGTGGACTGAGCTGGCAGACCTCACCAGATAGCCTTAGAGACTATTTTAGCAAATTTGGAGAAATTAGAGAATGTATGGTCA
TGAGAGATCCCACTACGAAACGCTCCAGAGGCTTCGGTTTCGTCACGTTCGCAGACCCAGCAAGTGTAGATAAAGTATTAGGTCAGCCCC
ACCATGAGTTAGATTCCAAGACGATTGACCCCAAAGTTGCATTTCCTCGTCGAGCGCAACCCAAGATGGTCACAAGAACAAAGAAAATAT
TTGTAGGCGGGTTATCTGCGAACACAGTAGTGGAAGATGTAAAGCAATATTTCGAGCAGTTTGGCAAGATTCGAAATCAGAGCAAAGCCT
CTGGGTCTGGGCTCTGTGAGGGAGATGAAGTGGTTTCCATCAATGGCAACCCTTGTGCAGATCTCACCTACCCTGAAGTCATCAAGCTCA
TGGAAAGCATAACAGACTCTCTCCAAATGCTCATCAAAAGACCATCCAGTGGAATAAGTGAGGCTTTGATATCTGAAAATGAAAACAAAA
ACCTCGAGCATCTCACACATGGGGGTTATGTGGAAAGTACCACCCTGCAGATTCGACCGGCCACAAAGACCCAGTGCACAGAATTCTTCC
TCGCCCCTGTCAAGACTGAAGTTCCCCTAGCTGAGAACCAAAGAAGTGGTCCCGACTGTGCAGGCAGCTTGAAAGAAGAAACAGGCCCGA
GCTACCAAAGGGCTCCCCAAATGCCTGACTCCCAAAGAGGACGCGTGGCAGAAGAGCTGATCTTAAGGGAGAAGGTAGAAGCGGTACAGC
CTGGGCCTGTGGTTGAGCTGCAACTGTCCCTTTCACAGGAGAGACATAAGGGCGCTAGTGGCCCTTTAGTGGCTCTCCCGGGAGCTGAAA
AATCTAAGTCTCCTGACCCAGACCCTAACTTGTCACATGACAGGATTGTCCACATAAATTCGATCCCTACTAATGAGAAAGCAGACCCTT
TCCTGAGGTCCAGCAAGATAATCCAGATCTCCAGTGGCAGAGAGTTGAGAGTGATCCAGGAAAGTGAAGCAGGAGATGCGGGACTGCCCC
GGGTGGAAGTGATCCTCGACTGCTCTGACAGGCAGAAGACAGAAGGGTGCAGGCTTCAGGCAGGAAAGGAGTGTGTGGATTCTCCAGTGG
AAGGAGGGCAGTCAGAAGCACCTCCTTCTCTGGTATCCTTTGCCGTCTCATCAGAAGGCACAGAGCAGGGAGAAGATCCACGCTCGGAAA
AAGATCACAGCAGACCTCACAAGCACCGAGCGCGGCATGCACGGCTCAGGAGGAGTGAAAGCCTGTCAGAAAAACAAGTGAAGGAAGCAA
AATCTAAATGCAAAAGCATTGCCCTTCTTCTAACGGATGCTCCCAACCCCAACTCCAAGGGGGTGTTGATGTTTAAGAAGCGACGTCGGA
GGGCCAGGAAATACACCCTAGTTAGCTACGGTACTGGCGAGCTTGAGCGAGAGGCGGACGAGGAGGAAGAAGGTGACAAGGAGGATACAT
GTGAAGTAGCATTTCTTGGTGCAAGCGAATCAGAGGTGGATGAAGAGTTATTGTCTGACGTTGACGACAACACACAAGTTGTGAACTTTG
ACTGGGATTCTGGACTGGTGGACATTGAAAAGAAACTGAACAGAGGGGACAAGATGGAGATGTTACCAGACACCACAGGCAAGGGAGCCC
TCATGTTTGCCAAGAGGAGGGAGAGAATGGATCAGATCACAGCCCAAAAAGAAGAGGACAAGGTAGGTGGAACGCCAAGCAGAGAACAAG
ATGCTGCCCAGACCGATGGCCTGAGAACCACGACTTCTTACCAAAGAAAGGAGGAAGAGTCGGTAAGAACGCAGAGCTCTGTGAGCAAAA
GCTACATCGAGGTGAGTCATGGTCTTGGCCATGTTCCCCAACAGAATGGCTTCAGTGGGACATCTGAGACAGCAAACATCCAGAGGATGG
TCCCCATGAATAGAACGGCCAAACCCTTCCCAGGGTCTGTGAATCAGCCAGCTACCCCCTTCTCGCCAACCCGAAACATGACGAGTCCCA
TTGCTGACTTTCCTGCACCTCCACCTTACTCTGCAGTCACTCCTCCCCCTGACGCCTTCTCCAGAGGGGTTTCAAGTCCGATTGCTGGCC
CAGCACAGCCCCCTCCATGGCCCCAGCCTGCCCCGTGGTCCCAGCCAGCCTTTTACGATTCGTCTGAGCGAATAGCTTCCCGAGATGAGA
GGATCTCAGTGCCAGCAAAAAGAACAGGAATATTGCAGGAGGCCAAAAGGAGAAGCACGACAAAACCCATGTTTACTTTTAAAGAGCCCA
AAGTAAGCCCAAATCCTGAACTCTTGTCACTCCTTCAAAATTCAGAAGGCAAACGGGGCACTGGAGCTGGAGGTGATTCCGGACCGGAAG
AAGACTACCTCAGCTTGGGGGCAGAGGCTTGTAATTTCATGCAAAGCTCCTCTGCCAAACAAAAGACCCCTCCTCCTGTTGCTCCAAAAC
CTGCAGTCAAGTCCTCATCCTCCCAACCAGTAACTCCAGTTTCCCCAGTCTGGTCTCCAGGAGTGGCTCCCACCCAACCTCCTGCCTTCC
CCACATCCAACCCATCAAAGGGCACCGTTGTCTCCTCCATCAAAATAGCCCAGCCTTCTTACCCTCCTGCCCGGCCTGCAAGTACTTTGA
ACGTGGCTGGTCCCTTCAAAGGACCACAAGCAGCAGTAGCCAGTCAGAATTACACACCCAAACCAACAGTTTCCACACCAACAGTCAATG
CTGTTCAGCCTGGTGCAGTGGGACCATCCAATGAGCTTCCAGGAATGAGTGGGAGAGGAGCTCAGCTCTTTGCTAAAAGGCAGTCGAGAA
TGGAGAAGTATGTGGTCGATTCAGACACGGTGCAGGCCCACGCTGCTCGAGCTCAGTCTCCCACTCCATCTCTCCCGGCCAGTTGGAAGT
ACTCCTCCAATGTCCGAGCACCTCCTCCTGTGGCCTATAATCCTATCCACTCGCCGTCTTACCCACTGGCTGCTCTCAAGTCTCAGCCAT
CAGCTGCACAGCCCTCCAAAATGGGCAAGAAAAAGGGAAAGAAACCCCTCAATGCATTAGATGTCATGAAGCACCAACCGTATCAGCTCA
ATGCATCCTTGTTTACTTTCCAACCTCCAGATGCAAAGGATGGCCTCCCCCAGAAGTCATCAGTCAAGGTCAATTCAGCCCTGGCCATGA
AGCAAGCTCTTCCTCCCCGGCCAGTGAATGCTGCCTCACCTACGAATGTGCAGGCTTCGTCAGTGTACTCGGTACCAGCCTATACCTCTC
CTCCTTCCTTCTTTGCAGAGGCCTCCTCACCAGTCAGTGCATCCCCAGTGCCTGTGGGCATTCCCACCTCGCCAAAGCAAGAATCAGCCT
CATCATCTTATTTTGTGGCACCAAGGCCAAAGTTCTCAGCCAAGAAAAGTGGTGTCACAATTCAGGTGTGGAAACCATCTGTTGTGGAAG
AGTAATCTTGTAGCTGAAGCTGAGTGTCCACTTTGCTTGAAATGAATTGTTTGCAGTGTTTCTTGAGTCCCTGAGAATGCCTAGCAAAGT
CCTCAACTTACTTAATTTCAGATATGTCACCTCCTAATCTGGGTCCAAGGAGTATAATATTTTTAATGAGTCAAAAATCCAACTCAGATT
GACCTAAAATATATTTATCTTCTTTGCACACTTAAAAAATCCAGGAGCACCCCAAAATAGACATGTACCGTTATATTAAGTAAGCAGGAG
ACTTAGGATTTGTGCTGTAGCCACAAGAAAGACAGTGATCAGTGATATCAAACATCAGGAATCAGCCTTTATGTAACATAACAGCTGTCC
TCCTATGGTGAAAGGTTCAAATGTAGTGAAGGTATAACCTATATTGACTGAGATTTCCCTTTTAGGTAGTGCCTTATCTCTATTACTAGT
GTTAAAGGAATAAGGAATCTATGAAGGACAGGGAGCAGCTCTGGTCTGTCAATCTCAGCCACCTGTTTGATATCACAGAGAAGATACTCG
GAGGATTGTTGGAATGTATATAGTTTAGTAAGAAGTGGGTAAGAAAGAGGGTCTTAATTACTGAGCACTTATTATGTATTAGGTTCTTTG
CCAGATGTTTTTACATATATAAACTCATTTCAGAAAACTTATTTAAAGTAAATGGGGCCGGGTATGGTGGTTCATGCCTGGAATCCTAGC
ACTTTGGGAGGCTGAGGTAGGAGGACTGCTTGAGGCCGGGAGTTGGAGACCAGCCTGAGCAACATAGTGAGACCCTGTCTCAATAATAAT
AATAATAATAGTAATAATGAAGTAAATGGGATAAGGAAAGAAGGATAATTATCTTTAAAGGTTGATTCCCACCCTCCCTCCCCAGTTACT
TAAGGAACTAAGTGAGTACATCTCCAGTTGCCCATGAAAGCATAAGTTTGTTTTCCTCAGCTGAGGCAAGTGGTAGAGTATACAGGATAA
CGAAGTAACATGTAAAAGGCAGGACGCACATAAAGGTGTACATGGCTATTGTTTCACCTGGAGAAACCACATGATTGGGACCTGAAGGTT
TACTGACTGACTACAGGGGCTGATTGTGAAGCACGAGGAACCCCATGTGTGTGGAGACTGTAGGGTGAGAGCACACAATTATTAGCATCA
TTTCTGAGTGATCTCACAGATTTTTTTTCTTGTGTTTGCTTTGCTTTTTGACAACTGCTTCTCCCACGTTCCTTGCAATTCTATTCTCTC
ACCTTCACTTTACTATTTGTATTCGATGGACCAGGATAATTCAGGCAAGGTTACCTTGTAAACTTTAATTGGCCACACACCATGTTGTCA
CCCAGCTGGCTATGAAGTGAATAATGGTACTGAAAGTAAACCTGAAGACCTTTCTCAGATCTATTTTAAGTCTGAGTCTGACCAACCATG
GAAAATATTCGACATGAATTAATGTAGAGAACTATAAAGCATTTATGACAGCTCCAAGAAAAATCATCTACTCTATGCAGGAGATATGTT
TAGAGACCTCTCAGAAAAACTTGCCTGGTTTGAGGGTACACAGTACCATTTTAATCTTCTGAAAATATCTGTATTCCTGCTCTTTTTCTG
CTGTCACTGTCAATCTGCTATATTTTTCACTATCCTATTAAAATATTACTGTCTCCTTTATCTGTTCAATGTCCATATTTTAAAAAAATC
TTCCTTGTATGAGCTATTCTGATCTAAATAATTTCTCTGATATTTCTCTATATGGCTCCCACAACAATTTCATTGTTGTTAGCATATCTA
TTTCTCCATACATTGTAAAACTGTAATCCTTAGGTATTTCTAAAACATAAAGAGGAGAATTAAGTCAGCTGCAGAACAATGGGGCTGATT
CTTCTGCTTTTTCTCTGGAAAATCTTTCATTGCTTTTGGTGGAAATTTACCTAGAGGTTACAACCACAGGATGTAGCTTGGTCTCTTATT
TGCCTTTTTGGGAAACCAATTAAGATTAATACAGGATAAAGGAAAAAAGCAATCTATTCATTATATAACACAGTTGTTTGTATTACTTGT
TCCCTGCAAAGGAAATCTGTTGAATGCTTGCATTTTGAATTCTTTTCTAATAGAACAACCAAAAAAGGCTTCTTATGGTGCAGCAGGAAA
AAAGATCATTTTTATAGCTTTGCATTCTTAACATAGCATTTAAAGAGCGGCATGAATTAGAGGAAAGACATGGAACACACAGGTAGTCGG
TTTGAGATCATCGGCTTAAAAGTATCCTAGGATGGTAATGACCCAGAAGTATTTCCAGTTGTCTAGTGGTGTGGTATGCAGGAATGAGAA
GTGTTTTCTTTCCATTTCCTGTTGGACAGGTGGCAATCTTAGCAGAGCCACTATTTGGAGTTGATAACTAAAGATGCAAATAACATGACT
ATGCCTTCTGGTCATCCTAGGACTATTTGGAGTTCTCCAAAACCTTGTAAGAGGCATGTCAGGCATGCAGTAAAAGCATCTACAACTTCA
GCTGGGCACTGGCAGCATAGGTCTCATCTTGGACCATACAGTCCCACTTTATAGAAGAGGGTGGAAGTTCTCCAAAACAATATCCACAAC
AAAGTCTGACCTCACTCTGAGGGAGATGGGAAGTGGGAGGAAGAAGGACTAACCAGCTCCCTGGAGTAAGAGGAATTTGCTTTCCCTGTC
TGCCCACCAGGGGCTATATGTGCCACCTTTCAGGTTGGGGCCAAGGAAGTGATGTCAGTGTGACAGAAGGGAGAGTTAGACCTCCAGACG
TCAGCCTCCCTCCCATGGGGTACATTTTCAATCTGAGTGTTGTTGCCTTAGCTGTGTTGGTATTAGCTTGATTGGTTGGTCCGCTGGTTA
TGAGGTGTAGGGAGGCAGTTTTTGTTTAGTTTTTAGGACTTTGCCTCTTCCTTTGTCCTTAGCATAATTTCTAGGCAGAGCATCCACGAA
GTCGGTTTTCATTGCCAGCTCAAGAGCGACAATCATTTACGAGTTCCTATGTTATGTTAGGTGCCTTATGTATATTATCCCAAATCCACT
GCATGGTTTAAATACAGGCACTGGAATATAAATGAAAAAGGTCATTACAGTCACTGACTTTCTGCAGGACCTTAAACATTTCTCTTTCCA
CAAGTTTCCCCTTAATCATGTGTCAAACCTCTCTTCCTGACGGGAATGTTGTGCTATAATGAATCTGCATAACGCTTGGGATTCTAGGAG
GAAGGAAGGTTCCATGGACATGTAAGTACAGCATATTCCCCTCAGTCTTCTAGGAGGGCAGAGTGAATCCCAGAACTGGTAAGATTGGGA
ATCTGAGCATTGCCACTTTAATCTTAGAATATTTATCATTTTGACACATCCTGTTTTTTAGAGAGGAAAACAAACACAGTTTCTGCATTG
GTAGTGTAAAGCATACCTTGTTAGGAACGTGTTTTGTAAGACACATTTGGGTTGTCACTCTAGAGCATGTCAAACTTTGTACTTCAAAAT
ATATTTAGTATGATTGTTAGTGGTAACATATATCAAGGCTTTGAATTAACTGTTTTATTTAATTTTCACAAGAAGCACTTATTTTAGCCA
TAGGAAAACCAATCTGAGCTACAAATAGTTCTTTAAAATAAGCCCAGGTTATTTAGCTATTCTAGAAAGTGCCGACTTCTTTCAAGAAGC
AGGCATTGTAGGACAGCTGAGAATTATCACATAGCCTAAATTCTAGCCTGGCAGCAAGAGTCACATCTGAGATGTCCAAAAAAAAAAAAA

>In-frame_ENST00000322684_ENST00000429713_TCGA-L3-A524-01A_MSI2_chr17_55478832_+_SYNPO2_chr4_119944585_length(amino acids)=1189AA_start in transcript=35_stop in transcript=3604
MADLTSVLTSVMFSPSSKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLGQPHHELDSKTIDPK
VAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKIRNQSKASGSGLCEGDEVVSINGNPCADLTYPEVIKLMESITDSLQMLI
KRPSSGISEALISENENKNLEHLTHGGYVESTTLQIRPATKTQCTEFFLAPVKTEVPLAENQRSGPDCAGSLKEETGPSYQRAPQMPDSQ
RGRVAEELILREKVEAVQPGPVVELQLSLSQERHKGASGPLVALPGAEKSKSPDPDPNLSHDRIVHINSIPTNEKADPFLRSSKIIQISS
GRELRVIQESEAGDAGLPRVEVILDCSDRQKTEGCRLQAGKECVDSPVEGGQSEAPPSLVSFAVSSEGTEQGEDPRSEKDHSRPHKHRAR
HARLRRSESLSEKQVKEAKSKCKSIALLLTDAPNPNSKGVLMFKKRRRRARKYTLVSYGTGELEREADEEEEGDKEDTCEVAFLGASESE
VDEELLSDVDDNTQVVNFDWDSGLVDIEKKLNRGDKMEMLPDTTGKGALMFAKRRERMDQITAQKEEDKVGGTPSREQDAAQTDGLRTTT
SYQRKEEESVRTQSSVSKSYIEVSHGLGHVPQQNGFSGTSETANIQRMVPMNRTAKPFPGSVNQPATPFSPTRNMTSPIADFPAPPPYSA
VTPPPDAFSRGVSSPIAGPAQPPPWPQPAPWSQPAFYDSSERIASRDERISVPAKRTGILQEAKRRSTTKPMFTFKEPKVSPNPELLSLL
QNSEGKRGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTPVSPVWSPGVAPTQPPAFPTSNPSKGTVVS
SIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNYTPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQ
AHAARAQSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLNALDVMKHQPYQLNASLFTFQPPDA
KDGLPQKSSVKVNSALAMKQALPPRPVNAASPTNVQASSVYSVPAYTSPPSFFAEASSPVSASPVPVGIPTSPKQESASSSYFVAPRPKF

--------------------------------------------------------------
>In-frame_ENST00000322684_ENST00000434046_TCGA-L3-A524-01A_MSI2_chr17_55478832_+_SYNPO2_chr4_119944585_length(transcript)=3847nt_BP=428nt
GCTTTCCTTTTAGCTTTTGTAAGTTACACGTCAAAATGGCCGATCTGACATCGGTGCTCACTTCTGTTATGTTTTCTCCCTCTAGTAAAA
TGTTTATCGGTGGACTGAGCTGGCAGACCTCACCAGATAGCCTTAGAGACTATTTTAGCAAATTTGGAGAAATTAGAGAATGTATGGTCA
TGAGAGATCCCACTACGAAACGCTCCAGAGGCTTCGGTTTCGTCACGTTCGCAGACCCAGCAAGTGTAGATAAAGTATTAGGTCAGCCCC
ACCATGAGTTAGATTCCAAGACGATTGACCCCAAAGTTGCATTTCCTCGTCGAGCGCAACCCAAGATGGTCACAAGAACAAAGAAAATAT
TTGTAGGCGGGTTATCTGCGAACACAGTAGTGGAAGATGTAAAGCAATATTTCGAGCAGTTTGGCAAGATTCGAAATCAGAGCAAAGCCT
CTGGGTCTGGGCTCTGTGAGGGAGATGAAGTGGTTTCCATCAATGGCAACCCTTGTGCAGATCTCACCTACCCTGAAGTCATCAAGCTCA
TGGAAAGCATAACAGACTCTCTCCAAATGCTCATCAAAAGACCATCCAGTGGAATAAGTGAGGCTTTGATATCTGAAAATGAAAACAAAA
ACCTCGAGCATCTCACACATGGGGGTTATGTGGAAAGTACCACCCTGCAGATTCGACCGGCCACAAAGACCCAGTGCACAGAATTCTTCC
TCGCCCCTGTCAAGACTGAAGTTCCCCTAGCTGAGAACCAAAGAAGTGGTCCCGACTGTGCAGGCAGCTTGAAAGAAGAAACAGGCCCGA
GCTACCAAAGGGCTCCCCAAATGCCTGACTCCCAAAGAGGACGCGTGGCAGAAGAGCTGATCTTAAGGGAGAAGGTAGAAGCGGTACAGC
CTGGGCCTGTGGTTGAGCTGCAACTGTCCCTTTCACAGGAGAGACATAAGGGCGCTAGTGGCCCTTTAGTGGCTCTCCCGGGAGCTGAAA
AATCTAAGTCTCCTGACCCAGACCCTAACTTGTCACATGACAGGATTGTCCACATAAATTCGATCCCTACTAATGAGAAAGCAGACCCTT
TCCTGAGGTCCAGCAAGATAATCCAGATCTCCAGTGGCAGAGAGTTGAGAGTGATCCAGGAAAGTGAAGCAGGAGATGCGGGACTGCCCC
GGGTGGAAGTGATCCTCGACTGCTCTGACAGGCAGAAGACAGAAGGGTGCAGGCTTCAGGCAGGAAAGGAGTGTGTGGATTCTCCAGTGG
AAGGAGGGCAGTCAGAAGCACCTCCTTCTCTGGTATCCTTTGCCGTCTCATCAGAAGGCACAGAGCAGGGAGAAGATCCACGCTCGGAAA
AAGATCACAGCAGACCTCACAAGCACCGAGCGCGGCATGCACGGCTCAGGAGGAGTGAAAGCCTGTCAGAAAAACAAGTGAAGGAAGCAA
AATCTAAATGCAAAAGCATTGCCCTTCTTCTAACGGATGCTCCCAACCCCAACTCCAAGGGGGTGTTGATGTTTAAGAAGCGACGTCGGA
GGGCCAGGAAATACACCCTAGTTAGCTACGGTACTGGCGAGCTTGAGCGAGAGGCGGACGAGGAGGAAGAAGGTGACAAGGAGGATACAT
GTGAAGTAGCATTTCTTGGTGCAAGCGAATCAGAGGTGGATGAAGAGTTATTGTCTGACGTTGACGACAACACACAAGTTGTGAACTTTG
ACTGGGATTCTGGACTGGTGGACATTGAAAAGAAACTGAACAGAGGGGACAAGATGGAGATGTTACCAGACACCACAGGCAAGGGAGCCC
TCATGTTTGCCAAGAGGAGGGAGAGAATGGATCAGATCACAGCCCAAAAAGAAGAGGACAAGGTAGGTGGAACGCCAAGCAGAGAACAAG
ATGCTGCCCAGACCGATGGCCTGAGAACCACGACTTCTTACCAAAGAAAGGAGGAAGAGTCGGTAAGAACGCAGAGCTCTGTGAGCAAAA
GCTACATCGAGGTGAGTCATGGTCTTGGCCATGTTCCCCAACAGAATGGCTTCAGTGGGACATCTGAGACAGCAAACATCCAGAGGATGG
TCCCCATGAATAGAACGGCCAAACCCTTCCCAGGGTCTGTGAATCAGCCAGCTACCCCCTTCTCGCCAACCCGAAACATGACGAGTCCCA
TTGCTGACTTTCCTGCACCTCCACCTTACTCTGCAGTCACTCCTCCCCCTGACGCCTTCTCCAGAGGGGTTTCAAGTCCGATTGCTGGCC
CAGCACAGCCCCCTCCATGGCCCCAGCCTGCCCCGTGGTCCCAGCCAGCCTTTTACGATTCGTCTGAGCGAATAGCTTCCCGAGATGAGA
GGATCTCAGTGCCAGCAAAAAGAACAGGAATATTGCAGGAGGCCAAAAGGAGAAGCACGACAAAACCCATGTTTACTTTTAAAGAGCCCA
AAGTAAGCCCAAATCCTGAACTCTTGTCACTCCTTCAAAATTCAGAAGGCAAACGGGGCACTGGAGCTGGAGGTGATTCCGGACCGGAAG
AAGACTACCTCAGCTTGGGGGCAGAGGCTTGTAATTTCATGCAAAGCTCCTCTGCCAAACAAAAGACCCCTCCTCCTGTTGCTCCAAAAC
CTGCAGTCAAGTCCTCATCCTCCCAACCAGTAACTCCAGTTTCCCCAGTCTGGTCTCCAGGAGTGGCTCCCACCCAACCTCCTGCCTTCC
CCACATCCAACCCATCAAAGGGCACCGTTGTCTCCTCCATCAAAATAGCCCAGCCTTCTTACCCTCCTGCCCGGCCTGCAAGTACTTTGA
ACGTGGCTGGTCCCTTCAAAGGACCACAAGCAGCAGTAGCCAGTCAGAATTACACACCCAAACCAACAGTTTCCACACCAACAGTCAATG
CTGTTCAGCCTGGTGCAGTGGGACCATCCAATGAGCTTCCAGGAATGAGTGGGAGAGGAGCTCAGCTCTTTGCTAAAAGGCAGTCGAGAA
TGGAGAAGTATGTGGTCGATTCAGACACGGTGCAGGCCCACGCTGCTCGAGCTCAGTCTCCCACTCCATCTCTCCCGGCCAGTTGGAAGT
ACTCCTCCAATGTCCGAGCACCTCCTCCTGTGGCCTATAATCCTATCCACTCGCCGTCTTACCCACTGGCTGCTCTCAAGTCTCAGCCAT
CAGCTGCACAGCCCTCCAAAATGGGCAAGAAAAAGGGAAAGAAACCCCTCAATGCATTAGATGTCATGAAGCACCAACCGTATCAGCTCA
ATGCATCCTTGTTTACTTTCCAACCTCCAGATGCAAAGGATGGCCTCCCCCAGAAGTCATCAGTCAAGGTCAATTCAGCCCTGGCCATGA
AGCAAGCTCTTCCTCCCCGGCCAGTGAATGCTGCCTCACCTACGAATGTGCAGGCTTCGTCAGTGTACTCGGTACCAGCCTATACCTCTC
CTCCTTCCTTCTTTGCAGAGGCCTCCTCACCAGTCAGTGCATCCCCAGTGCCTGTGGGCATTCCCACCTCGCCAAAGCAAGAATCAGCCT
CATCATCTTATTTTGTGGCACCAAGGCCAAAGTTCTCAGCCAAGAAAAGTGGTGTCACAATTCAGGTGAAATGTAAATCTGGGATCCATA
GTCAAGATATCATAAGGACCTACTTCCCAGCCTACCTTTCTTCCTCTACCTGATAATGATAATACTCAAAATAACAACATTCAAAGGAAA
CACAAAGAAATCCTGCTTTCACATCTCCTATTTCTTGGGCTCCTTAATAACTACTGATGGTTTGTTCATGAAAAAAAATTTTTAAATCAA

>In-frame_ENST00000322684_ENST00000434046_TCGA-L3-A524-01A_MSI2_chr17_55478832_+_SYNPO2_chr4_119944585_length(amino acids)=1205AA_start in transcript=35_stop in transcript=3652
MADLTSVLTSVMFSPSSKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLGQPHHELDSKTIDPK
VAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKIRNQSKASGSGLCEGDEVVSINGNPCADLTYPEVIKLMESITDSLQMLI
KRPSSGISEALISENENKNLEHLTHGGYVESTTLQIRPATKTQCTEFFLAPVKTEVPLAENQRSGPDCAGSLKEETGPSYQRAPQMPDSQ
RGRVAEELILREKVEAVQPGPVVELQLSLSQERHKGASGPLVALPGAEKSKSPDPDPNLSHDRIVHINSIPTNEKADPFLRSSKIIQISS
GRELRVIQESEAGDAGLPRVEVILDCSDRQKTEGCRLQAGKECVDSPVEGGQSEAPPSLVSFAVSSEGTEQGEDPRSEKDHSRPHKHRAR
HARLRRSESLSEKQVKEAKSKCKSIALLLTDAPNPNSKGVLMFKKRRRRARKYTLVSYGTGELEREADEEEEGDKEDTCEVAFLGASESE
VDEELLSDVDDNTQVVNFDWDSGLVDIEKKLNRGDKMEMLPDTTGKGALMFAKRRERMDQITAQKEEDKVGGTPSREQDAAQTDGLRTTT
SYQRKEEESVRTQSSVSKSYIEVSHGLGHVPQQNGFSGTSETANIQRMVPMNRTAKPFPGSVNQPATPFSPTRNMTSPIADFPAPPPYSA
VTPPPDAFSRGVSSPIAGPAQPPPWPQPAPWSQPAFYDSSERIASRDERISVPAKRTGILQEAKRRSTTKPMFTFKEPKVSPNPELLSLL
QNSEGKRGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTPVSPVWSPGVAPTQPPAFPTSNPSKGTVVS
SIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNYTPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQ
AHAARAQSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLNALDVMKHQPYQLNASLFTFQPPDA
KDGLPQKSSVKVNSALAMKQALPPRPVNAASPTNVQASSVYSVPAYTSPPSFFAEASSPVSASPVPVGIPTSPKQESASSSYFVAPRPKF

--------------------------------------------------------------
>In-frame_ENST00000442934_ENST00000307142_TCGA-L3-A524-01A_MSI2_chr17_55478832_+_SYNPO2_chr4_119944585_length(transcript)=7256nt_BP=262nt
TTTCTGTTGTGTAGTTCTGATTTTCCGAACAGGTGTTTAGATGATGAGGGGTTATATTAAGAAAGTACTAAAGAATACGTCTTATCACGT
GAATCAGTATCTTTTTATTCAACATGGATGGAGTGGGAGTGGAGACCAATCTGTTTTATATTCCTGCAATCTGATGAGGATGGTCACAAG
AACAAAGAAAATATTTGTAGGCGGGTTATCTGCGAACACAGTAGTGGAAGATGTAAAGCAATATTTCGAGCAGTTTGGCAAGATTCGAAA
TCAGAGCAAAGCCTCTGGGTCTGGGCTCTGTGAGGGAGATGAAGTGGTTTCCATCAATGGCAACCCTTGTGCAGATCTCACCTACCCTGA
AGTCATCAAGCTCATGGAAAGCATAACAGACTCTCTCCAAATGCTCATCAAAAGACCATCCAGTGGAATAAGTGAGGCTTTGATATCTGA
AAATGAAAACAAAAACCTCGAGCATCTCACACATGGGGGTTATGTGGAAAGTACCACCCTGCAGATTCGACCGGCCACAAAGACCCAGTG
CACAGAATTCTTCCTCGCCCCTGTCAAGACTGAAGTTCCCCTAGCTGAGAACCAAAGAAGTGGTCCCGACTGTGCAGGCAGCTTGAAAGA
AGAAACAGGCCCGAGCTACCAAAGGGCTCCCCAAATGCCTGACTCCCAAAGAGGACGCGTGGCAGAAGAGCTGATCTTAAGGGAGAAGGT
AGAAGCGGTACAGCCTGGGCCTGTGGTTGAGCTGCAACTGTCCCTTTCACAGGAGAGACATAAGGGCGCTAGTGGCCCTTTAGTGGCTCT
CCCGGGAGCTGAAAAATCTAAGTCTCCTGACCCAGACCCTAACTTGTCACATGACAGGATTGTCCACATAAATTCGATCCCTACTAATGA
GAAAGCAGACCCTTTCCTGAGGTCCAGCAAGATAATCCAGATCTCCAGTGGCAGAGAGTTGAGAGTGATCCAGGAAAGTGAAGCAGGAGA
TGCGGGACTGCCCCGGGTGGAAGTGATCCTCGACTGCTCTGACAGGCAGAAGACAGAAGGGTGCAGGCTTCAGGCAGGAAAGGAGTGTGT
GGATTCTCCAGTGGAAGGAGGGCAGTCAGAAGCACCTCCTTCTCTGGTATCCTTTGCCGTCTCATCAGAAGGCACAGAGCAGGGAGAAGA
TCCACGCTCGGAAAAAGATCACAGCAGACCTCACAAGCACCGAGCGCGGCATGCACGGCTCAGGAGGAGTGAAAGCCTGTCAGAAAAACA
AGTGAAGGAAGCAAAATCTAAATGCAAAAGCATTGCCCTTCTTCTAACGGATGCTCCCAACCCCAACTCCAAGGGGGTGTTGATGTTTAA
GAAGCGACGTCGGAGGGCCAGGAAATACACCCTAGTTAGCTACGGTACTGGCGAGCTTGAGCGAGAGGCGGACGAGGAGGAAGAAGGTGA
CAAGGAGGATACATGTGAAGTAGCATTTCTTGGTGCAAGCGAATCAGAGGTGGATGAAGAGTTATTGTCTGACGTTGACGACAACACACA
AGTTGTGAACTTTGACTGGGATTCTGGACTGGTGGACATTGAAAAGAAACTGAACAGAGGGGACAAGATGGAGATGTTACCAGACACCAC
AGGCAAGGGAGCCCTCATGTTTGCCAAGAGGAGGGAGAGAATGGATCAGATCACAGCCCAAAAAGAAGAGGACAAGGTAGGTGGAACGCC
AAGCAGAGAACAAGATGCTGCCCAGACCGATGGCCTGAGAACCACGACTTCTTACCAAAGAAAGGAGGAAGAGTCGGTAAGAACGCAGAG
CTCTGTGAGCAAAAGCTACATCGAGGTGAGTCATGGTCTTGGCCATGTTCCCCAACAGAATGGCTTCAGTGGGACATCTGAGACAGCAAA
CATCCAGAGGATGGTCCCCATGAATAGAACGGCCAAACCCTTCCCAGGGTCTGTGAATCAGCCAGCTACCCCCTTCTCGCCAACCCGAAA
CATGACGAGTCCCATTGCTGACTTTCCTGCACCTCCACCTTACTCTGCAGTCACTCCTCCCCCTGACGCCTTCTCCAGAGGGGTTTCAAG
TCCGATTGCTGGCCCAGCACAGCCCCCTCCATGGCCCCAGCCTGCCCCGTGGTCCCAGCCAGCCTTTTACGATTCGTCTGAGCGAATAGC
TTCCCGAGATGAGAGGATCTCAGTGCCAGCAAAAAGAACAGGAATATTGCAGGAGGCCAAAAGGAGAAGCACGACAAAACCCATGTTTAC
TTTTAAAGAGCCCAAAGTAAGCCCAAATCCTGAACTCTTGTCACTCCTTCAAAATTCAGAAGGCAAACGGGGCACTGGAGCTGGAGGTGA
TTCCGGACCGGAAGAAGACTACCTCAGCTTGGGGGCAGAGGCTTGTAATTTCATGCAAAGCTCCTCTGCCAAACAAAAGACCCCTCCTCC
TGTTGCTCCAAAACCTGCAGTCAAGTCCTCATCCTCCCAACCAGTAACTCCAGTTTCCCCAGTCTGGTCTCCAGGAGTGGCTCCCACCCA
ACCTCCTGCCTTCCCCACATCCAACCCATCAAAGGGCACCGTTGTCTCCTCCATCAAAATAGCCCAGCCTTCTTACCCTCCTGCCCGGCC
TGCAAGTACTTTGAACGTGGCTGGTCCCTTCAAAGGACCACAAGCAGCAGTAGCCAGTCAGAATTACACACCCAAACCAACAGTTTCCAC
ACCAACAGTCAATGCTGTTCAGCCTGGTGCAGTGGGACCATCCAATGAGCTTCCAGGAATGAGTGGGAGAGGAGCTCAGCTCTTTGCTAA
AAGGCAGTCGAGAATGGAGAAGTATGTGGTCGATTCAGACACGGTGCAGGCCCACGCTGCTCGAGCTCAGTCTCCCACTCCATCTCTCCC
GGCCAGTTGGAAGTACTCCTCCAATGTCCGAGCACCTCCTCCTGTGGCCTATAATCCTATCCACTCGCCGTCTTACCCACTGGCTGCTCT
CAAGTCTCAGCCATCAGCTGCACAGCCCTCCAAAATGGGCAAGAAAAAGGGAAAGAAACCCCTCAATGCATTAGATGTCATGAAGCACCA
ACCGTATCAGCTCAATGCATCCTTGTTTACTTTCCAACCTCCAGATGCAAAGGATGGCCTCCCCCAGAAGTCATCAGTCAAGGTCAATTC
AGCCCTGGCCATGAAGCAAGCTCTTCCTCCCCGGCCAGTGAATGCTGCCTCACCTACGAATGTGCAGGCTTCGTCAGTGTACTCGGTACC
AGCCTATACCTCTCCTCCTTCCTTCTTTGCAGAGGCCTCCTCACCAGTCAGTGCATCCCCAGTGCCTGTGGGCATTCCCACCTCGCCAAA
GCAAGAATCAGCCTCATCATCTTATTTTGTGGCACCAAGGCCAAAGTTCTCAGCCAAGAAAAGTGGTGTCACAATTCAGGAGAGTGGGCG
CTCCCTTTCTCTTCCTGGAAGATCAGTCCCACCCCCCATTTCTACATCTCCTTGGGTATACCAGCCTACTTATAGTTACTCTAGTAAACC
AACCGATGGACTAGAGAAAGCAAACAAGAGACCAACTCCTTGGGAAGCAGCAGCAAAGTCTCCTCTCGGTCTAGTGGATGATGCTTTCCA
ACCCAGAAACATCCAGGAATCCATTGTGGCAAATGTGGTTTCAGCAGCTCGGAGGAAGGTGCTTCCAGGGCCTCCAGAGGATTGGAATGA
AAGACTGTCCTATATTCCTCAAACCCAGAAGGCCTATATGGGCTCATGTGGAAGGCAAGAGTATAATGTCACAGCCAATAATAATATGTC
CACCACCTCCCAATATGGTTCACAGTTGCCATATGCATATTATAGGCAGGCTTCAAGAAATGATTCTGCAATCATGTCCATGGAAACCAG
GTCTGATTACTGTCTTCCAGTAGCTGATTACAACTACAACCCACACCCAAGGGGATGGAGACGCCAAACATGAAAGTTAGAAGAACGGAT
CATGTGCCAACTGTAGTTTTTTAAAAAAAACGCTCCTTTGTAGGGTTTTAAACTTTTCTAATAGATTTAGATTCACTTTTGGTCTTGGCT
TGTTCTCATAAGTCATTTATCTAAGTTTGTGTTTCTGTGTGTGTGTGTGTGTGTGTATGTATGTGAATATACACACACACACACACACAG
GTGAGTGTGAATACTTCCTTGTTGGCTGATCCATAGAGCATTACTTGGAAGAAAATTTCACTATTTGCATTGATGTGCTGGCATTTATAT
GTAATTCATAATTTTGATTCCATTAATAGGTAGTCTATGCAACAAACTCTACTCAATTAAAGTAAAACTAAGTATTTCTTCATTGTACCT
TAGTCCAGGAAGAAATTAATGGAATATGGTGTGCTAATTATCACTACCTATAACATGAGGAATATAACATTGCAGAAATTTCTCATAGGG
GCATGCCAGTGAGCAATTACTTTATAAAAATATTTTCCTTGGTGTTAAGTATTTCTCTGCAACTTTTTTTTTTTTTTTTTTTTTTTTTTG
AGATGGAGTCTTGCTCTGTCCCACCCAGTCTGGAGTGCAATGGTGCGATCTTGGCTCACTGCAACCTGCGCCTCCTGGGTTCAAGCAATT
CTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGCATGAACCACCACACCTGGATAATTTTTGTATTTTTAGTAGACACAAAGTTTC
ACCATGTTGGTCAGACTGGTCTTGAACTCCTGACCTCGTGATCTGCCCGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCAC
CACACCTGGCCTTTCTGCAACATTTTTTTAAAAAAATCTAATAAATCTTAGATTTTTAAAAAAGAATTAAAATGTGGGAGTTCTCAGAAA
GAAATAAACACATGAGAATAAGATTATTACACATTTTGGAAGGACTTTTGAGGAATGATGTGATGTGTAGAGAATAGAAAGATTTAGATA
TATGCCTGTGACAGGAATAGATTCTGGGTTCAGGGGTCCCCATCTGTCAAATGAGAAGATTGGATTATCTAATCTTTTAGATCCTTAACA
ACTCTGATATTCTGAGATTCTCTCATTTGTAGAATGCCCGCTGATGCATTGTTTATTTTTTTTGCTCATAATATAAATATCAGATTATGT
TTAGGAGTGGATTAGGTAATTAGTGTCACTACATGTATCATTAAAGGTCCTAAAAGGAATTGTTAGGCGGCAGGCTTTGTGTTACGTGTT
ACATGGAGTGAGGGTAGATGTGAAGATTTAAAACGATTGATGGATTTAAGGAAGTGGTACATAAATATGTCTGTTATTATGCAATCGTAG
GTCATGATAATTTATTCAGTTATAGAAAACATGCCACAGAAGCCTATGTAACAAGTGGTGCTTCTTTAGAAAGTTGTCATTAGAATGTTC
TGAGGAAGTTAAGCAGCTGCTTCATCAATCCCATGACACATGCCTTGTTAGCATGCCCATCAAATAATCAGATCAAACACCTGCTCCTTA
TTGCCATACCCACGAACTGTTAAATATAAAAAAATTCAAAGTATTTGACATCTTAAGCAAATATCCAGAATATTTTTAAGTAAAAAACCA
TCTTAAGTATTCAAAATTTCCTTGGTTTTTTAAAGGTGATAATTTTGCTTTGTGTTACTTTTTTGCTCTTGAATGTATCGTTATGATGGT
CTCTTATAATCATGGTATCTTTCACAGAATAAAAATTAAAAATAATGCCAGGGTGCAAGTGACCAAGGCCTTATCTTGAAAGTTAAAAAA
AAAAAGTAAAGAAATCACAGTAAGTTCTATTAGTGATGATAGAACCAGATATAAAATTGTTCAGTGATGGAGAAAAGAAACGATAAATAC
TTTCCAAGGTTATATTGTTAAATTATCTTAAATTATCAAGGTGTAAGATGTAATGATCCCAAGAGTTTTTATAGAATCCTAAAAAATAAC
GCCTGATGTATAGATTAGTTAGCAAATTCTCAGAAATCCCCCACATAAAAGCCTTACTTTGTTCAAAATTTATTATAGTGGTTTAATCAT
TTTAGATTTGAATGTTTTAAGATAGGAGAGACTTAGCAGAAAATACTTGGCTTGCCAGGGCCACGTTCTACTTCATTGCTTTCTTTTATA
AGTGCAAGGAGTTATTTCCATCAGTTGACATAGATATTATTCACTAAAATTTTCAGCAGACTCAAAATAGAGAGGAGACTTTAAACTTAC
ATGTTAGCATAAAACAGACTTCTCTCTCATTGCATGCACTAGATCAATATTATCATCTGTATTAAGCTATCTGAATTTATTCGAGACATT
AAGAAAAAGACAGTACATGGTGGGAAAGCTGCACATTTCTCACAAGGAAAAAAACATTCTATATTTGTAGCAGAAATCAGTGGTTTGAAA
AGTCATACTTTGCAGATATGAACCTGAAAATCAAAGTGCCATTGTTAAATCATCCTAAAGTGTACTGTGGGTATTCTCCAGCATACTTGA
AAATGAATAAAGTTAGATTGCTCACATTGAAGCTAATGGTTGAGACAAGACACCTGCCAGAGTGAAGTTTGATTCCTATGGGTGAGAAGA
TGTAGATGACTATTGTTCTCACTAAAGTTCTAAAATAATAGCAAGTGTAGAGAAGAGCCGTTGCTTTGAAAATACATACCACATTTGTTA
TAAAGCATTTGTTTGTTAGTATCAATCACATAGGTAGAAAGAGTTTGAGTTTTACTGTGGATTAAAAAGCCTTCCCTAAAAAGAGAGCAT
GCCAGTCATAGAGACACTAATTTGGCACTTTTCCTCCTTCTTAGGTTTAAATGTTATACCAATGCATGTGTTTGAAATATCCATTAAGAT
GATTTAAAATTTGTCTTGTATTTTGAGTTTCTTAAATGCGTGGATTCTTGTTCATTTATCTCTGAATATGTCTCTTTTATATTTTGGCAC
AATTATACACATTGGAAAGGGCCAACCTATTAGGGCTCAAGTATGTATATGCAAAAAAAAAAAGTTATATCAAACAGGCACAGTTATTAC
AACTAGAGAGAAATTCCAGAAATATTTGTTTTTTTAAGAGAAAGTAAATTTTCACATTAGATTTCTATTCAAAGTACTAATATCTACATG
GTCCACACTTTTCTATTTTAAAAAATTGTGTTCTCTTGTTAAATAGATTAACATTTCCACTTCTGTTTATCACAAAAGACTGTATTTGAA

>In-frame_ENST00000442934_ENST00000307142_TCGA-L3-A524-01A_MSI2_chr17_55478832_+_SYNPO2_chr4_119944585_length(amino acids)=1300AA_start in transcript=40_stop in transcript=3942
MMRGYIKKVLKNTSYHVNQYLFIQHGWSGSGDQSVLYSCNLMRMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKIRNQSKASGSGLCEGD
EVVSINGNPCADLTYPEVIKLMESITDSLQMLIKRPSSGISEALISENENKNLEHLTHGGYVESTTLQIRPATKTQCTEFFLAPVKTEVP
LAENQRSGPDCAGSLKEETGPSYQRAPQMPDSQRGRVAEELILREKVEAVQPGPVVELQLSLSQERHKGASGPLVALPGAEKSKSPDPDP
NLSHDRIVHINSIPTNEKADPFLRSSKIIQISSGRELRVIQESEAGDAGLPRVEVILDCSDRQKTEGCRLQAGKECVDSPVEGGQSEAPP
SLVSFAVSSEGTEQGEDPRSEKDHSRPHKHRARHARLRRSESLSEKQVKEAKSKCKSIALLLTDAPNPNSKGVLMFKKRRRRARKYTLVS
YGTGELEREADEEEEGDKEDTCEVAFLGASESEVDEELLSDVDDNTQVVNFDWDSGLVDIEKKLNRGDKMEMLPDTTGKGALMFAKRRER
MDQITAQKEEDKVGGTPSREQDAAQTDGLRTTTSYQRKEEESVRTQSSVSKSYIEVSHGLGHVPQQNGFSGTSETANIQRMVPMNRTAKP
FPGSVNQPATPFSPTRNMTSPIADFPAPPPYSAVTPPPDAFSRGVSSPIAGPAQPPPWPQPAPWSQPAFYDSSERIASRDERISVPAKRT
GILQEAKRRSTTKPMFTFKEPKVSPNPELLSLLQNSEGKRGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQ
PVTPVSPVWSPGVAPTQPPAFPTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNYTPKPTVSTPTVNAVQPGAVGP
SNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARAQSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMG
KKKGKKPLNALDVMKHQPYQLNASLFTFQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNAASPTNVQASSVYSVPAYTSPPSFFAEAS
SPVSASPVPVGIPTSPKQESASSSYFVAPRPKFSAKKSGVTIQESGRSLSLPGRSVPPPISTSPWVYQPTYSYSSKPTDGLEKANKRPTP
WEAAAKSPLGLVDDAFQPRNIQESIVANVVSAARRKVLPGPPEDWNERLSYIPQTQKAYMGSCGRQEYNVTANNNMSTTSQYGSQLPYAY

--------------------------------------------------------------
>In-frame_ENST00000442934_ENST00000448416_TCGA-L3-A524-01A_MSI2_chr17_55478832_+_SYNPO2_chr4_119944585_length(transcript)=1306nt_BP=262nt
TTTCTGTTGTGTAGTTCTGATTTTCCGAACAGGTGTTTAGATGATGAGGGGTTATATTAAGAAAGTACTAAAGAATACGTCTTATCACGT
GAATCAGTATCTTTTTATTCAACATGGATGGAGTGGGAGTGGAGACCAATCTGTTTTATATTCCTGCAATCTGATGAGGATGGTCACAAG
AACAAAGAAAATATTTGTAGGCGGGTTATCTGCGAACACAGTAGTGGAAGATGTAAAGCAATATTTCGAGCAGTTTGGCAAGATTCGAAA
TCAGAGCAAAGCCTCTGGGTCTGGGCTCTGTGAGGGAGATGAAGTGGTTTCCATCAATGGCAACCCTTGTGCAGATCTCACCTACCCTGA
AGTCATCAAGCTCATGGAAAGCATAACAGACTCTCTCCAAATGCTCATCAAAAGGAGAGTGGGCGCTCCCTTTCTCTTCCTGGAAGATCA
GTCCCACCCCCCATTTCTACATCTCCTTGGGTATACCAGCCTACTTATAGTTACTCTAGTAAACCAACCGATGGACTAGAGAAAGCAAAC
AAGAGACCAACTCCTTGGGAAGCAGCAGCAAAGTCTCCTCTCGGTCTAGTGGATGATGCTTTCCAACCCAGAAACATCCAGGAATCCATT
GTGGCAAATGTGGTTTCAGCAGCTCGGAGGAAGGTGCTTCCAGGGCCTCCAGAGGATTGGAATGAAAGACTGTCCTATATTCCTCAAACC
CAGAAGGCCTATATGGGCTCATGTGGAAGGCAAGAGTATAATGTCACAGCCAATAATAATATGTCCACCACCTCCCAATATGGTTCACAG
TTGCCATATGCATATTATAGGCAGGCTTCAAGAAATGATTCTGCAATCATGTCCATGGAAACCAGGTCTGATTACTGTCTTCCAGTAGCT
GATTACAACTACAACCCACACCCAAGGGGATGGAGACGCCAAACATGAAAGTTAGAAGAACGGATCATGTGCCAACTGTAGTTTTTTAAA
AAAAACGCTCCTTTGTAGGGTTTTAAACTTTTCTAATAGATTTAGATTCACTTTTGGTCTTGGCTTGTTCTCATAAGTCATTTATCTAAG
TTTGTGTTTCTGTGTGTGTGTGTGTGTGTGTATGTATGTGAATATACACACACACACACACACAGGTGAGTGTGAATACTTCCTTGTTGG
CTGATCCATAGAGCATTACTTGGAAGAAAATTTCACTATTTGCATTGATGTGCTGGCATTTATATGTAATTCATAATTTTGATTCCATTA

>In-frame_ENST00000442934_ENST00000448416_TCGA-L3-A524-01A_MSI2_chr17_55478832_+_SYNPO2_chr4_119944585_length(amino acids)=162AA_start in transcript=40_stop in transcript=528
MMRGYIKKVLKNTSYHVNQYLFIQHGWSGSGDQSVLYSCNLMRMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKIRNQSKASGSGLCEGD

--------------------------------------------------------------
>In-frame_ENST00000442934_ENST00000429713_TCGA-L3-A524-01A_MSI2_chr17_55478832_+_SYNPO2_chr4_119944585_length(transcript)=7217nt_BP=262nt
TTTCTGTTGTGTAGTTCTGATTTTCCGAACAGGTGTTTAGATGATGAGGGGTTATATTAAGAAAGTACTAAAGAATACGTCTTATCACGT
GAATCAGTATCTTTTTATTCAACATGGATGGAGTGGGAGTGGAGACCAATCTGTTTTATATTCCTGCAATCTGATGAGGATGGTCACAAG
AACAAAGAAAATATTTGTAGGCGGGTTATCTGCGAACACAGTAGTGGAAGATGTAAAGCAATATTTCGAGCAGTTTGGCAAGATTCGAAA
TCAGAGCAAAGCCTCTGGGTCTGGGCTCTGTGAGGGAGATGAAGTGGTTTCCATCAATGGCAACCCTTGTGCAGATCTCACCTACCCTGA
AGTCATCAAGCTCATGGAAAGCATAACAGACTCTCTCCAAATGCTCATCAAAAGACCATCCAGTGGAATAAGTGAGGCTTTGATATCTGA
AAATGAAAACAAAAACCTCGAGCATCTCACACATGGGGGTTATGTGGAAAGTACCACCCTGCAGATTCGACCGGCCACAAAGACCCAGTG
CACAGAATTCTTCCTCGCCCCTGTCAAGACTGAAGTTCCCCTAGCTGAGAACCAAAGAAGTGGTCCCGACTGTGCAGGCAGCTTGAAAGA
AGAAACAGGCCCGAGCTACCAAAGGGCTCCCCAAATGCCTGACTCCCAAAGAGGACGCGTGGCAGAAGAGCTGATCTTAAGGGAGAAGGT
AGAAGCGGTACAGCCTGGGCCTGTGGTTGAGCTGCAACTGTCCCTTTCACAGGAGAGACATAAGGGCGCTAGTGGCCCTTTAGTGGCTCT
CCCGGGAGCTGAAAAATCTAAGTCTCCTGACCCAGACCCTAACTTGTCACATGACAGGATTGTCCACATAAATTCGATCCCTACTAATGA
GAAAGCAGACCCTTTCCTGAGGTCCAGCAAGATAATCCAGATCTCCAGTGGCAGAGAGTTGAGAGTGATCCAGGAAAGTGAAGCAGGAGA
TGCGGGACTGCCCCGGGTGGAAGTGATCCTCGACTGCTCTGACAGGCAGAAGACAGAAGGGTGCAGGCTTCAGGCAGGAAAGGAGTGTGT
GGATTCTCCAGTGGAAGGAGGGCAGTCAGAAGCACCTCCTTCTCTGGTATCCTTTGCCGTCTCATCAGAAGGCACAGAGCAGGGAGAAGA
TCCACGCTCGGAAAAAGATCACAGCAGACCTCACAAGCACCGAGCGCGGCATGCACGGCTCAGGAGGAGTGAAAGCCTGTCAGAAAAACA
AGTGAAGGAAGCAAAATCTAAATGCAAAAGCATTGCCCTTCTTCTAACGGATGCTCCCAACCCCAACTCCAAGGGGGTGTTGATGTTTAA
GAAGCGACGTCGGAGGGCCAGGAAATACACCCTAGTTAGCTACGGTACTGGCGAGCTTGAGCGAGAGGCGGACGAGGAGGAAGAAGGTGA
CAAGGAGGATACATGTGAAGTAGCATTTCTTGGTGCAAGCGAATCAGAGGTGGATGAAGAGTTATTGTCTGACGTTGACGACAACACACA
AGTTGTGAACTTTGACTGGGATTCTGGACTGGTGGACATTGAAAAGAAACTGAACAGAGGGGACAAGATGGAGATGTTACCAGACACCAC
AGGCAAGGGAGCCCTCATGTTTGCCAAGAGGAGGGAGAGAATGGATCAGATCACAGCCCAAAAAGAAGAGGACAAGGTAGGTGGAACGCC
AAGCAGAGAACAAGATGCTGCCCAGACCGATGGCCTGAGAACCACGACTTCTTACCAAAGAAAGGAGGAAGAGTCGGTAAGAACGCAGAG
CTCTGTGAGCAAAAGCTACATCGAGGTGAGTCATGGTCTTGGCCATGTTCCCCAACAGAATGGCTTCAGTGGGACATCTGAGACAGCAAA
CATCCAGAGGATGGTCCCCATGAATAGAACGGCCAAACCCTTCCCAGGGTCTGTGAATCAGCCAGCTACCCCCTTCTCGCCAACCCGAAA
CATGACGAGTCCCATTGCTGACTTTCCTGCACCTCCACCTTACTCTGCAGTCACTCCTCCCCCTGACGCCTTCTCCAGAGGGGTTTCAAG
TCCGATTGCTGGCCCAGCACAGCCCCCTCCATGGCCCCAGCCTGCCCCGTGGTCCCAGCCAGCCTTTTACGATTCGTCTGAGCGAATAGC
TTCCCGAGATGAGAGGATCTCAGTGCCAGCAAAAAGAACAGGAATATTGCAGGAGGCCAAAAGGAGAAGCACGACAAAACCCATGTTTAC
TTTTAAAGAGCCCAAAGTAAGCCCAAATCCTGAACTCTTGTCACTCCTTCAAAATTCAGAAGGCAAACGGGGCACTGGAGCTGGAGGTGA
TTCCGGACCGGAAGAAGACTACCTCAGCTTGGGGGCAGAGGCTTGTAATTTCATGCAAAGCTCCTCTGCCAAACAAAAGACCCCTCCTCC
TGTTGCTCCAAAACCTGCAGTCAAGTCCTCATCCTCCCAACCAGTAACTCCAGTTTCCCCAGTCTGGTCTCCAGGAGTGGCTCCCACCCA
ACCTCCTGCCTTCCCCACATCCAACCCATCAAAGGGCACCGTTGTCTCCTCCATCAAAATAGCCCAGCCTTCTTACCCTCCTGCCCGGCC
TGCAAGTACTTTGAACGTGGCTGGTCCCTTCAAAGGACCACAAGCAGCAGTAGCCAGTCAGAATTACACACCCAAACCAACAGTTTCCAC
ACCAACAGTCAATGCTGTTCAGCCTGGTGCAGTGGGACCATCCAATGAGCTTCCAGGAATGAGTGGGAGAGGAGCTCAGCTCTTTGCTAA
AAGGCAGTCGAGAATGGAGAAGTATGTGGTCGATTCAGACACGGTGCAGGCCCACGCTGCTCGAGCTCAGTCTCCCACTCCATCTCTCCC
GGCCAGTTGGAAGTACTCCTCCAATGTCCGAGCACCTCCTCCTGTGGCCTATAATCCTATCCACTCGCCGTCTTACCCACTGGCTGCTCT
CAAGTCTCAGCCATCAGCTGCACAGCCCTCCAAAATGGGCAAGAAAAAGGGAAAGAAACCCCTCAATGCATTAGATGTCATGAAGCACCA
ACCGTATCAGCTCAATGCATCCTTGTTTACTTTCCAACCTCCAGATGCAAAGGATGGCCTCCCCCAGAAGTCATCAGTCAAGGTCAATTC
AGCCCTGGCCATGAAGCAAGCTCTTCCTCCCCGGCCAGTGAATGCTGCCTCACCTACGAATGTGCAGGCTTCGTCAGTGTACTCGGTACC
AGCCTATACCTCTCCTCCTTCCTTCTTTGCAGAGGCCTCCTCACCAGTCAGTGCATCCCCAGTGCCTGTGGGCATTCCCACCTCGCCAAA
GCAAGAATCAGCCTCATCATCTTATTTTGTGGCACCAAGGCCAAAGTTCTCAGCCAAGAAAAGTGGTGTCACAATTCAGGTGTGGAAACC
ATCTGTTGTGGAAGAGTAATCTTGTAGCTGAAGCTGAGTGTCCACTTTGCTTGAAATGAATTGTTTGCAGTGTTTCTTGAGTCCCTGAGA
ATGCCTAGCAAAGTCCTCAACTTACTTAATTTCAGATATGTCACCTCCTAATCTGGGTCCAAGGAGTATAATATTTTTAATGAGTCAAAA
ATCCAACTCAGATTGACCTAAAATATATTTATCTTCTTTGCACACTTAAAAAATCCAGGAGCACCCCAAAATAGACATGTACCGTTATAT
TAAGTAAGCAGGAGACTTAGGATTTGTGCTGTAGCCACAAGAAAGACAGTGATCAGTGATATCAAACATCAGGAATCAGCCTTTATGTAA
CATAACAGCTGTCCTCCTATGGTGAAAGGTTCAAATGTAGTGAAGGTATAACCTATATTGACTGAGATTTCCCTTTTAGGTAGTGCCTTA
TCTCTATTACTAGTGTTAAAGGAATAAGGAATCTATGAAGGACAGGGAGCAGCTCTGGTCTGTCAATCTCAGCCACCTGTTTGATATCAC
AGAGAAGATACTCGGAGGATTGTTGGAATGTATATAGTTTAGTAAGAAGTGGGTAAGAAAGAGGGTCTTAATTACTGAGCACTTATTATG
TATTAGGTTCTTTGCCAGATGTTTTTACATATATAAACTCATTTCAGAAAACTTATTTAAAGTAAATGGGGCCGGGTATGGTGGTTCATG
CCTGGAATCCTAGCACTTTGGGAGGCTGAGGTAGGAGGACTGCTTGAGGCCGGGAGTTGGAGACCAGCCTGAGCAACATAGTGAGACCCT
GTCTCAATAATAATAATAATAATAGTAATAATGAAGTAAATGGGATAAGGAAAGAAGGATAATTATCTTTAAAGGTTGATTCCCACCCTC
CCTCCCCAGTTACTTAAGGAACTAAGTGAGTACATCTCCAGTTGCCCATGAAAGCATAAGTTTGTTTTCCTCAGCTGAGGCAAGTGGTAG
AGTATACAGGATAACGAAGTAACATGTAAAAGGCAGGACGCACATAAAGGTGTACATGGCTATTGTTTCACCTGGAGAAACCACATGATT
GGGACCTGAAGGTTTACTGACTGACTACAGGGGCTGATTGTGAAGCACGAGGAACCCCATGTGTGTGGAGACTGTAGGGTGAGAGCACAC
AATTATTAGCATCATTTCTGAGTGATCTCACAGATTTTTTTTCTTGTGTTTGCTTTGCTTTTTGACAACTGCTTCTCCCACGTTCCTTGC
AATTCTATTCTCTCACCTTCACTTTACTATTTGTATTCGATGGACCAGGATAATTCAGGCAAGGTTACCTTGTAAACTTTAATTGGCCAC
ACACCATGTTGTCACCCAGCTGGCTATGAAGTGAATAATGGTACTGAAAGTAAACCTGAAGACCTTTCTCAGATCTATTTTAAGTCTGAG
TCTGACCAACCATGGAAAATATTCGACATGAATTAATGTAGAGAACTATAAAGCATTTATGACAGCTCCAAGAAAAATCATCTACTCTAT
GCAGGAGATATGTTTAGAGACCTCTCAGAAAAACTTGCCTGGTTTGAGGGTACACAGTACCATTTTAATCTTCTGAAAATATCTGTATTC
CTGCTCTTTTTCTGCTGTCACTGTCAATCTGCTATATTTTTCACTATCCTATTAAAATATTACTGTCTCCTTTATCTGTTCAATGTCCAT
ATTTTAAAAAAATCTTCCTTGTATGAGCTATTCTGATCTAAATAATTTCTCTGATATTTCTCTATATGGCTCCCACAACAATTTCATTGT
TGTTAGCATATCTATTTCTCCATACATTGTAAAACTGTAATCCTTAGGTATTTCTAAAACATAAAGAGGAGAATTAAGTCAGCTGCAGAA
CAATGGGGCTGATTCTTCTGCTTTTTCTCTGGAAAATCTTTCATTGCTTTTGGTGGAAATTTACCTAGAGGTTACAACCACAGGATGTAG
CTTGGTCTCTTATTTGCCTTTTTGGGAAACCAATTAAGATTAATACAGGATAAAGGAAAAAAGCAATCTATTCATTATATAACACAGTTG
TTTGTATTACTTGTTCCCTGCAAAGGAAATCTGTTGAATGCTTGCATTTTGAATTCTTTTCTAATAGAACAACCAAAAAAGGCTTCTTAT
GGTGCAGCAGGAAAAAAGATCATTTTTATAGCTTTGCATTCTTAACATAGCATTTAAAGAGCGGCATGAATTAGAGGAAAGACATGGAAC
ACACAGGTAGTCGGTTTGAGATCATCGGCTTAAAAGTATCCTAGGATGGTAATGACCCAGAAGTATTTCCAGTTGTCTAGTGGTGTGGTA
TGCAGGAATGAGAAGTGTTTTCTTTCCATTTCCTGTTGGACAGGTGGCAATCTTAGCAGAGCCACTATTTGGAGTTGATAACTAAAGATG
CAAATAACATGACTATGCCTTCTGGTCATCCTAGGACTATTTGGAGTTCTCCAAAACCTTGTAAGAGGCATGTCAGGCATGCAGTAAAAG
CATCTACAACTTCAGCTGGGCACTGGCAGCATAGGTCTCATCTTGGACCATACAGTCCCACTTTATAGAAGAGGGTGGAAGTTCTCCAAA
ACAATATCCACAACAAAGTCTGACCTCACTCTGAGGGAGATGGGAAGTGGGAGGAAGAAGGACTAACCAGCTCCCTGGAGTAAGAGGAAT
TTGCTTTCCCTGTCTGCCCACCAGGGGCTATATGTGCCACCTTTCAGGTTGGGGCCAAGGAAGTGATGTCAGTGTGACAGAAGGGAGAGT
TAGACCTCCAGACGTCAGCCTCCCTCCCATGGGGTACATTTTCAATCTGAGTGTTGTTGCCTTAGCTGTGTTGGTATTAGCTTGATTGGT
TGGTCCGCTGGTTATGAGGTGTAGGGAGGCAGTTTTTGTTTAGTTTTTAGGACTTTGCCTCTTCCTTTGTCCTTAGCATAATTTCTAGGC
AGAGCATCCACGAAGTCGGTTTTCATTGCCAGCTCAAGAGCGACAATCATTTACGAGTTCCTATGTTATGTTAGGTGCCTTATGTATATT
ATCCCAAATCCACTGCATGGTTTAAATACAGGCACTGGAATATAAATGAAAAAGGTCATTACAGTCACTGACTTTCTGCAGGACCTTAAA
CATTTCTCTTTCCACAAGTTTCCCCTTAATCATGTGTCAAACCTCTCTTCCTGACGGGAATGTTGTGCTATAATGAATCTGCATAACGCT
TGGGATTCTAGGAGGAAGGAAGGTTCCATGGACATGTAAGTACAGCATATTCCCCTCAGTCTTCTAGGAGGGCAGAGTGAATCCCAGAAC
TGGTAAGATTGGGAATCTGAGCATTGCCACTTTAATCTTAGAATATTTATCATTTTGACACATCCTGTTTTTTAGAGAGGAAAACAAACA
CAGTTTCTGCATTGGTAGTGTAAAGCATACCTTGTTAGGAACGTGTTTTGTAAGACACATTTGGGTTGTCACTCTAGAGCATGTCAAACT
TTGTACTTCAAAATATATTTAGTATGATTGTTAGTGGTAACATATATCAAGGCTTTGAATTAACTGTTTTATTTAATTTTCACAAGAAGC
ACTTATTTTAGCCATAGGAAAACCAATCTGAGCTACAAATAGTTCTTTAAAATAAGCCCAGGTTATTTAGCTATTCTAGAAAGTGCCGAC
TTCTTTCAAGAAGCAGGCATTGTAGGACAGCTGAGAATTATCACATAGCCTAAATTCTAGCCTGGCAGCAAGAGTCACATCTGAGATGTC

>In-frame_ENST00000442934_ENST00000429713_TCGA-L3-A524-01A_MSI2_chr17_55478832_+_SYNPO2_chr4_119944585_length(amino acids)=1132AA_start in transcript=40_stop in transcript=3438
MMRGYIKKVLKNTSYHVNQYLFIQHGWSGSGDQSVLYSCNLMRMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKIRNQSKASGSGLCEGD
EVVSINGNPCADLTYPEVIKLMESITDSLQMLIKRPSSGISEALISENENKNLEHLTHGGYVESTTLQIRPATKTQCTEFFLAPVKTEVP
LAENQRSGPDCAGSLKEETGPSYQRAPQMPDSQRGRVAEELILREKVEAVQPGPVVELQLSLSQERHKGASGPLVALPGAEKSKSPDPDP
NLSHDRIVHINSIPTNEKADPFLRSSKIIQISSGRELRVIQESEAGDAGLPRVEVILDCSDRQKTEGCRLQAGKECVDSPVEGGQSEAPP
SLVSFAVSSEGTEQGEDPRSEKDHSRPHKHRARHARLRRSESLSEKQVKEAKSKCKSIALLLTDAPNPNSKGVLMFKKRRRRARKYTLVS
YGTGELEREADEEEEGDKEDTCEVAFLGASESEVDEELLSDVDDNTQVVNFDWDSGLVDIEKKLNRGDKMEMLPDTTGKGALMFAKRRER
MDQITAQKEEDKVGGTPSREQDAAQTDGLRTTTSYQRKEEESVRTQSSVSKSYIEVSHGLGHVPQQNGFSGTSETANIQRMVPMNRTAKP
FPGSVNQPATPFSPTRNMTSPIADFPAPPPYSAVTPPPDAFSRGVSSPIAGPAQPPPWPQPAPWSQPAFYDSSERIASRDERISVPAKRT
GILQEAKRRSTTKPMFTFKEPKVSPNPELLSLLQNSEGKRGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQ
PVTPVSPVWSPGVAPTQPPAFPTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNYTPKPTVSTPTVNAVQPGAVGP
SNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARAQSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMG
KKKGKKPLNALDVMKHQPYQLNASLFTFQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNAASPTNVQASSVYSVPAYTSPPSFFAEAS

--------------------------------------------------------------
>In-frame_ENST00000442934_ENST00000434046_TCGA-L3-A524-01A_MSI2_chr17_55478832_+_SYNPO2_chr4_119944585_length(transcript)=3681nt_BP=262nt
TTTCTGTTGTGTAGTTCTGATTTTCCGAACAGGTGTTTAGATGATGAGGGGTTATATTAAGAAAGTACTAAAGAATACGTCTTATCACGT
GAATCAGTATCTTTTTATTCAACATGGATGGAGTGGGAGTGGAGACCAATCTGTTTTATATTCCTGCAATCTGATGAGGATGGTCACAAG
AACAAAGAAAATATTTGTAGGCGGGTTATCTGCGAACACAGTAGTGGAAGATGTAAAGCAATATTTCGAGCAGTTTGGCAAGATTCGAAA
TCAGAGCAAAGCCTCTGGGTCTGGGCTCTGTGAGGGAGATGAAGTGGTTTCCATCAATGGCAACCCTTGTGCAGATCTCACCTACCCTGA
AGTCATCAAGCTCATGGAAAGCATAACAGACTCTCTCCAAATGCTCATCAAAAGACCATCCAGTGGAATAAGTGAGGCTTTGATATCTGA
AAATGAAAACAAAAACCTCGAGCATCTCACACATGGGGGTTATGTGGAAAGTACCACCCTGCAGATTCGACCGGCCACAAAGACCCAGTG
CACAGAATTCTTCCTCGCCCCTGTCAAGACTGAAGTTCCCCTAGCTGAGAACCAAAGAAGTGGTCCCGACTGTGCAGGCAGCTTGAAAGA
AGAAACAGGCCCGAGCTACCAAAGGGCTCCCCAAATGCCTGACTCCCAAAGAGGACGCGTGGCAGAAGAGCTGATCTTAAGGGAGAAGGT
AGAAGCGGTACAGCCTGGGCCTGTGGTTGAGCTGCAACTGTCCCTTTCACAGGAGAGACATAAGGGCGCTAGTGGCCCTTTAGTGGCTCT
CCCGGGAGCTGAAAAATCTAAGTCTCCTGACCCAGACCCTAACTTGTCACATGACAGGATTGTCCACATAAATTCGATCCCTACTAATGA
GAAAGCAGACCCTTTCCTGAGGTCCAGCAAGATAATCCAGATCTCCAGTGGCAGAGAGTTGAGAGTGATCCAGGAAAGTGAAGCAGGAGA
TGCGGGACTGCCCCGGGTGGAAGTGATCCTCGACTGCTCTGACAGGCAGAAGACAGAAGGGTGCAGGCTTCAGGCAGGAAAGGAGTGTGT
GGATTCTCCAGTGGAAGGAGGGCAGTCAGAAGCACCTCCTTCTCTGGTATCCTTTGCCGTCTCATCAGAAGGCACAGAGCAGGGAGAAGA
TCCACGCTCGGAAAAAGATCACAGCAGACCTCACAAGCACCGAGCGCGGCATGCACGGCTCAGGAGGAGTGAAAGCCTGTCAGAAAAACA
AGTGAAGGAAGCAAAATCTAAATGCAAAAGCATTGCCCTTCTTCTAACGGATGCTCCCAACCCCAACTCCAAGGGGGTGTTGATGTTTAA
GAAGCGACGTCGGAGGGCCAGGAAATACACCCTAGTTAGCTACGGTACTGGCGAGCTTGAGCGAGAGGCGGACGAGGAGGAAGAAGGTGA
CAAGGAGGATACATGTGAAGTAGCATTTCTTGGTGCAAGCGAATCAGAGGTGGATGAAGAGTTATTGTCTGACGTTGACGACAACACACA
AGTTGTGAACTTTGACTGGGATTCTGGACTGGTGGACATTGAAAAGAAACTGAACAGAGGGGACAAGATGGAGATGTTACCAGACACCAC
AGGCAAGGGAGCCCTCATGTTTGCCAAGAGGAGGGAGAGAATGGATCAGATCACAGCCCAAAAAGAAGAGGACAAGGTAGGTGGAACGCC
AAGCAGAGAACAAGATGCTGCCCAGACCGATGGCCTGAGAACCACGACTTCTTACCAAAGAAAGGAGGAAGAGTCGGTAAGAACGCAGAG
CTCTGTGAGCAAAAGCTACATCGAGGTGAGTCATGGTCTTGGCCATGTTCCCCAACAGAATGGCTTCAGTGGGACATCTGAGACAGCAAA
CATCCAGAGGATGGTCCCCATGAATAGAACGGCCAAACCCTTCCCAGGGTCTGTGAATCAGCCAGCTACCCCCTTCTCGCCAACCCGAAA
CATGACGAGTCCCATTGCTGACTTTCCTGCACCTCCACCTTACTCTGCAGTCACTCCTCCCCCTGACGCCTTCTCCAGAGGGGTTTCAAG
TCCGATTGCTGGCCCAGCACAGCCCCCTCCATGGCCCCAGCCTGCCCCGTGGTCCCAGCCAGCCTTTTACGATTCGTCTGAGCGAATAGC
TTCCCGAGATGAGAGGATCTCAGTGCCAGCAAAAAGAACAGGAATATTGCAGGAGGCCAAAAGGAGAAGCACGACAAAACCCATGTTTAC
TTTTAAAGAGCCCAAAGTAAGCCCAAATCCTGAACTCTTGTCACTCCTTCAAAATTCAGAAGGCAAACGGGGCACTGGAGCTGGAGGTGA
TTCCGGACCGGAAGAAGACTACCTCAGCTTGGGGGCAGAGGCTTGTAATTTCATGCAAAGCTCCTCTGCCAAACAAAAGACCCCTCCTCC
TGTTGCTCCAAAACCTGCAGTCAAGTCCTCATCCTCCCAACCAGTAACTCCAGTTTCCCCAGTCTGGTCTCCAGGAGTGGCTCCCACCCA
ACCTCCTGCCTTCCCCACATCCAACCCATCAAAGGGCACCGTTGTCTCCTCCATCAAAATAGCCCAGCCTTCTTACCCTCCTGCCCGGCC
TGCAAGTACTTTGAACGTGGCTGGTCCCTTCAAAGGACCACAAGCAGCAGTAGCCAGTCAGAATTACACACCCAAACCAACAGTTTCCAC
ACCAACAGTCAATGCTGTTCAGCCTGGTGCAGTGGGACCATCCAATGAGCTTCCAGGAATGAGTGGGAGAGGAGCTCAGCTCTTTGCTAA
AAGGCAGTCGAGAATGGAGAAGTATGTGGTCGATTCAGACACGGTGCAGGCCCACGCTGCTCGAGCTCAGTCTCCCACTCCATCTCTCCC
GGCCAGTTGGAAGTACTCCTCCAATGTCCGAGCACCTCCTCCTGTGGCCTATAATCCTATCCACTCGCCGTCTTACCCACTGGCTGCTCT
CAAGTCTCAGCCATCAGCTGCACAGCCCTCCAAAATGGGCAAGAAAAAGGGAAAGAAACCCCTCAATGCATTAGATGTCATGAAGCACCA
ACCGTATCAGCTCAATGCATCCTTGTTTACTTTCCAACCTCCAGATGCAAAGGATGGCCTCCCCCAGAAGTCATCAGTCAAGGTCAATTC
AGCCCTGGCCATGAAGCAAGCTCTTCCTCCCCGGCCAGTGAATGCTGCCTCACCTACGAATGTGCAGGCTTCGTCAGTGTACTCGGTACC
AGCCTATACCTCTCCTCCTTCCTTCTTTGCAGAGGCCTCCTCACCAGTCAGTGCATCCCCAGTGCCTGTGGGCATTCCCACCTCGCCAAA
GCAAGAATCAGCCTCATCATCTTATTTTGTGGCACCAAGGCCAAAGTTCTCAGCCAAGAAAAGTGGTGTCACAATTCAGGTGAAATGTAA
ATCTGGGATCCATAGTCAAGATATCATAAGGACCTACTTCCCAGCCTACCTTTCTTCCTCTACCTGATAATGATAATACTCAAAATAACA
ACATTCAAAGGAAACACAAAGAAATCCTGCTTTCACATCTCCTATTTCTTGGGCTCCTTAATAACTACTGATGGTTTGTTCATGAAAAAA

>In-frame_ENST00000442934_ENST00000434046_TCGA-L3-A524-01A_MSI2_chr17_55478832_+_SYNPO2_chr4_119944585_length(amino acids)=1148AA_start in transcript=40_stop in transcript=3486
MMRGYIKKVLKNTSYHVNQYLFIQHGWSGSGDQSVLYSCNLMRMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKIRNQSKASGSGLCEGD
EVVSINGNPCADLTYPEVIKLMESITDSLQMLIKRPSSGISEALISENENKNLEHLTHGGYVESTTLQIRPATKTQCTEFFLAPVKTEVP
LAENQRSGPDCAGSLKEETGPSYQRAPQMPDSQRGRVAEELILREKVEAVQPGPVVELQLSLSQERHKGASGPLVALPGAEKSKSPDPDP
NLSHDRIVHINSIPTNEKADPFLRSSKIIQISSGRELRVIQESEAGDAGLPRVEVILDCSDRQKTEGCRLQAGKECVDSPVEGGQSEAPP
SLVSFAVSSEGTEQGEDPRSEKDHSRPHKHRARHARLRRSESLSEKQVKEAKSKCKSIALLLTDAPNPNSKGVLMFKKRRRRARKYTLVS
YGTGELEREADEEEEGDKEDTCEVAFLGASESEVDEELLSDVDDNTQVVNFDWDSGLVDIEKKLNRGDKMEMLPDTTGKGALMFAKRRER
MDQITAQKEEDKVGGTPSREQDAAQTDGLRTTTSYQRKEEESVRTQSSVSKSYIEVSHGLGHVPQQNGFSGTSETANIQRMVPMNRTAKP
FPGSVNQPATPFSPTRNMTSPIADFPAPPPYSAVTPPPDAFSRGVSSPIAGPAQPPPWPQPAPWSQPAFYDSSERIASRDERISVPAKRT
GILQEAKRRSTTKPMFTFKEPKVSPNPELLSLLQNSEGKRGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQ
PVTPVSPVWSPGVAPTQPPAFPTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNYTPKPTVSTPTVNAVQPGAVGP
SNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARAQSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMG
KKKGKKPLNALDVMKHQPYQLNASLFTFQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNAASPTNVQASSVYSVPAYTSPPSFFAEAS

--------------------------------------------------------------
>In-frame_ENST00000579180_ENST00000307142_TCGA-L3-A524-01A_MSI2_chr17_55478832_+_SYNPO2_chr4_119944585_length(transcript)=7192nt_BP=198nt
CAAGTCAGTCGATCCTGTGTTTGTGCTCCCGAAGGACTTGGCGACTTGGCTAACAAGGAGACATTTGTTATTTCATTTCCTCATCCATTA
TTCATGCAGTGAGAGATGGTCACAAGAACAAAGAAAATATTTGTAGGCGGGTTATCTGCGAACACAGTAGTGGAAGATGTAAAGCAATAT
TTCGAGCAGTTTGGCAAGATTCGAAATCAGAGCAAAGCCTCTGGGTCTGGGCTCTGTGAGGGAGATGAAGTGGTTTCCATCAATGGCAAC
CCTTGTGCAGATCTCACCTACCCTGAAGTCATCAAGCTCATGGAAAGCATAACAGACTCTCTCCAAATGCTCATCAAAAGACCATCCAGT
GGAATAAGTGAGGCTTTGATATCTGAAAATGAAAACAAAAACCTCGAGCATCTCACACATGGGGGTTATGTGGAAAGTACCACCCTGCAG
ATTCGACCGGCCACAAAGACCCAGTGCACAGAATTCTTCCTCGCCCCTGTCAAGACTGAAGTTCCCCTAGCTGAGAACCAAAGAAGTGGT
CCCGACTGTGCAGGCAGCTTGAAAGAAGAAACAGGCCCGAGCTACCAAAGGGCTCCCCAAATGCCTGACTCCCAAAGAGGACGCGTGGCA
GAAGAGCTGATCTTAAGGGAGAAGGTAGAAGCGGTACAGCCTGGGCCTGTGGTTGAGCTGCAACTGTCCCTTTCACAGGAGAGACATAAG
GGCGCTAGTGGCCCTTTAGTGGCTCTCCCGGGAGCTGAAAAATCTAAGTCTCCTGACCCAGACCCTAACTTGTCACATGACAGGATTGTC
CACATAAATTCGATCCCTACTAATGAGAAAGCAGACCCTTTCCTGAGGTCCAGCAAGATAATCCAGATCTCCAGTGGCAGAGAGTTGAGA
GTGATCCAGGAAAGTGAAGCAGGAGATGCGGGACTGCCCCGGGTGGAAGTGATCCTCGACTGCTCTGACAGGCAGAAGACAGAAGGGTGC
AGGCTTCAGGCAGGAAAGGAGTGTGTGGATTCTCCAGTGGAAGGAGGGCAGTCAGAAGCACCTCCTTCTCTGGTATCCTTTGCCGTCTCA
TCAGAAGGCACAGAGCAGGGAGAAGATCCACGCTCGGAAAAAGATCACAGCAGACCTCACAAGCACCGAGCGCGGCATGCACGGCTCAGG
AGGAGTGAAAGCCTGTCAGAAAAACAAGTGAAGGAAGCAAAATCTAAATGCAAAAGCATTGCCCTTCTTCTAACGGATGCTCCCAACCCC
AACTCCAAGGGGGTGTTGATGTTTAAGAAGCGACGTCGGAGGGCCAGGAAATACACCCTAGTTAGCTACGGTACTGGCGAGCTTGAGCGA
GAGGCGGACGAGGAGGAAGAAGGTGACAAGGAGGATACATGTGAAGTAGCATTTCTTGGTGCAAGCGAATCAGAGGTGGATGAAGAGTTA
TTGTCTGACGTTGACGACAACACACAAGTTGTGAACTTTGACTGGGATTCTGGACTGGTGGACATTGAAAAGAAACTGAACAGAGGGGAC
AAGATGGAGATGTTACCAGACACCACAGGCAAGGGAGCCCTCATGTTTGCCAAGAGGAGGGAGAGAATGGATCAGATCACAGCCCAAAAA
GAAGAGGACAAGGTAGGTGGAACGCCAAGCAGAGAACAAGATGCTGCCCAGACCGATGGCCTGAGAACCACGACTTCTTACCAAAGAAAG
GAGGAAGAGTCGGTAAGAACGCAGAGCTCTGTGAGCAAAAGCTACATCGAGGTGAGTCATGGTCTTGGCCATGTTCCCCAACAGAATGGC
TTCAGTGGGACATCTGAGACAGCAAACATCCAGAGGATGGTCCCCATGAATAGAACGGCCAAACCCTTCCCAGGGTCTGTGAATCAGCCA
GCTACCCCCTTCTCGCCAACCCGAAACATGACGAGTCCCATTGCTGACTTTCCTGCACCTCCACCTTACTCTGCAGTCACTCCTCCCCCT
GACGCCTTCTCCAGAGGGGTTTCAAGTCCGATTGCTGGCCCAGCACAGCCCCCTCCATGGCCCCAGCCTGCCCCGTGGTCCCAGCCAGCC
TTTTACGATTCGTCTGAGCGAATAGCTTCCCGAGATGAGAGGATCTCAGTGCCAGCAAAAAGAACAGGAATATTGCAGGAGGCCAAAAGG
AGAAGCACGACAAAACCCATGTTTACTTTTAAAGAGCCCAAAGTAAGCCCAAATCCTGAACTCTTGTCACTCCTTCAAAATTCAGAAGGC
AAACGGGGCACTGGAGCTGGAGGTGATTCCGGACCGGAAGAAGACTACCTCAGCTTGGGGGCAGAGGCTTGTAATTTCATGCAAAGCTCC
TCTGCCAAACAAAAGACCCCTCCTCCTGTTGCTCCAAAACCTGCAGTCAAGTCCTCATCCTCCCAACCAGTAACTCCAGTTTCCCCAGTC
TGGTCTCCAGGAGTGGCTCCCACCCAACCTCCTGCCTTCCCCACATCCAACCCATCAAAGGGCACCGTTGTCTCCTCCATCAAAATAGCC
CAGCCTTCTTACCCTCCTGCCCGGCCTGCAAGTACTTTGAACGTGGCTGGTCCCTTCAAAGGACCACAAGCAGCAGTAGCCAGTCAGAAT
TACACACCCAAACCAACAGTTTCCACACCAACAGTCAATGCTGTTCAGCCTGGTGCAGTGGGACCATCCAATGAGCTTCCAGGAATGAGT
GGGAGAGGAGCTCAGCTCTTTGCTAAAAGGCAGTCGAGAATGGAGAAGTATGTGGTCGATTCAGACACGGTGCAGGCCCACGCTGCTCGA
GCTCAGTCTCCCACTCCATCTCTCCCGGCCAGTTGGAAGTACTCCTCCAATGTCCGAGCACCTCCTCCTGTGGCCTATAATCCTATCCAC
TCGCCGTCTTACCCACTGGCTGCTCTCAAGTCTCAGCCATCAGCTGCACAGCCCTCCAAAATGGGCAAGAAAAAGGGAAAGAAACCCCTC
AATGCATTAGATGTCATGAAGCACCAACCGTATCAGCTCAATGCATCCTTGTTTACTTTCCAACCTCCAGATGCAAAGGATGGCCTCCCC
CAGAAGTCATCAGTCAAGGTCAATTCAGCCCTGGCCATGAAGCAAGCTCTTCCTCCCCGGCCAGTGAATGCTGCCTCACCTACGAATGTG
CAGGCTTCGTCAGTGTACTCGGTACCAGCCTATACCTCTCCTCCTTCCTTCTTTGCAGAGGCCTCCTCACCAGTCAGTGCATCCCCAGTG
CCTGTGGGCATTCCCACCTCGCCAAAGCAAGAATCAGCCTCATCATCTTATTTTGTGGCACCAAGGCCAAAGTTCTCAGCCAAGAAAAGT
GGTGTCACAATTCAGGAGAGTGGGCGCTCCCTTTCTCTTCCTGGAAGATCAGTCCCACCCCCCATTTCTACATCTCCTTGGGTATACCAG
CCTACTTATAGTTACTCTAGTAAACCAACCGATGGACTAGAGAAAGCAAACAAGAGACCAACTCCTTGGGAAGCAGCAGCAAAGTCTCCT
CTCGGTCTAGTGGATGATGCTTTCCAACCCAGAAACATCCAGGAATCCATTGTGGCAAATGTGGTTTCAGCAGCTCGGAGGAAGGTGCTT
CCAGGGCCTCCAGAGGATTGGAATGAAAGACTGTCCTATATTCCTCAAACCCAGAAGGCCTATATGGGCTCATGTGGAAGGCAAGAGTAT
AATGTCACAGCCAATAATAATATGTCCACCACCTCCCAATATGGTTCACAGTTGCCATATGCATATTATAGGCAGGCTTCAAGAAATGAT
TCTGCAATCATGTCCATGGAAACCAGGTCTGATTACTGTCTTCCAGTAGCTGATTACAACTACAACCCACACCCAAGGGGATGGAGACGC
CAAACATGAAAGTTAGAAGAACGGATCATGTGCCAACTGTAGTTTTTTAAAAAAAACGCTCCTTTGTAGGGTTTTAAACTTTTCTAATAG
ATTTAGATTCACTTTTGGTCTTGGCTTGTTCTCATAAGTCATTTATCTAAGTTTGTGTTTCTGTGTGTGTGTGTGTGTGTGTATGTATGT
GAATATACACACACACACACACACAGGTGAGTGTGAATACTTCCTTGTTGGCTGATCCATAGAGCATTACTTGGAAGAAAATTTCACTAT
TTGCATTGATGTGCTGGCATTTATATGTAATTCATAATTTTGATTCCATTAATAGGTAGTCTATGCAACAAACTCTACTCAATTAAAGTA
AAACTAAGTATTTCTTCATTGTACCTTAGTCCAGGAAGAAATTAATGGAATATGGTGTGCTAATTATCACTACCTATAACATGAGGAATA
TAACATTGCAGAAATTTCTCATAGGGGCATGCCAGTGAGCAATTACTTTATAAAAATATTTTCCTTGGTGTTAAGTATTTCTCTGCAACT
TTTTTTTTTTTTTTTTTTTTTTTTTGAGATGGAGTCTTGCTCTGTCCCACCCAGTCTGGAGTGCAATGGTGCGATCTTGGCTCACTGCAA
CCTGCGCCTCCTGGGTTCAAGCAATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGCATGAACCACCACACCTGGATAATTTT
TGTATTTTTAGTAGACACAAAGTTTCACCATGTTGGTCAGACTGGTCTTGAACTCCTGACCTCGTGATCTGCCCGCCTCAGCCTCCCAAA
GTGCTGGGATTACAGGCGTGAGCCACCACACCTGGCCTTTCTGCAACATTTTTTTAAAAAAATCTAATAAATCTTAGATTTTTAAAAAAG
AATTAAAATGTGGGAGTTCTCAGAAAGAAATAAACACATGAGAATAAGATTATTACACATTTTGGAAGGACTTTTGAGGAATGATGTGAT
GTGTAGAGAATAGAAAGATTTAGATATATGCCTGTGACAGGAATAGATTCTGGGTTCAGGGGTCCCCATCTGTCAAATGAGAAGATTGGA
TTATCTAATCTTTTAGATCCTTAACAACTCTGATATTCTGAGATTCTCTCATTTGTAGAATGCCCGCTGATGCATTGTTTATTTTTTTTG
CTCATAATATAAATATCAGATTATGTTTAGGAGTGGATTAGGTAATTAGTGTCACTACATGTATCATTAAAGGTCCTAAAAGGAATTGTT
AGGCGGCAGGCTTTGTGTTACGTGTTACATGGAGTGAGGGTAGATGTGAAGATTTAAAACGATTGATGGATTTAAGGAAGTGGTACATAA
ATATGTCTGTTATTATGCAATCGTAGGTCATGATAATTTATTCAGTTATAGAAAACATGCCACAGAAGCCTATGTAACAAGTGGTGCTTC
TTTAGAAAGTTGTCATTAGAATGTTCTGAGGAAGTTAAGCAGCTGCTTCATCAATCCCATGACACATGCCTTGTTAGCATGCCCATCAAA
TAATCAGATCAAACACCTGCTCCTTATTGCCATACCCACGAACTGTTAAATATAAAAAAATTCAAAGTATTTGACATCTTAAGCAAATAT
CCAGAATATTTTTAAGTAAAAAACCATCTTAAGTATTCAAAATTTCCTTGGTTTTTTAAAGGTGATAATTTTGCTTTGTGTTACTTTTTT
GCTCTTGAATGTATCGTTATGATGGTCTCTTATAATCATGGTATCTTTCACAGAATAAAAATTAAAAATAATGCCAGGGTGCAAGTGACC
AAGGCCTTATCTTGAAAGTTAAAAAAAAAAAGTAAAGAAATCACAGTAAGTTCTATTAGTGATGATAGAACCAGATATAAAATTGTTCAG
TGATGGAGAAAAGAAACGATAAATACTTTCCAAGGTTATATTGTTAAATTATCTTAAATTATCAAGGTGTAAGATGTAATGATCCCAAGA
GTTTTTATAGAATCCTAAAAAATAACGCCTGATGTATAGATTAGTTAGCAAATTCTCAGAAATCCCCCACATAAAAGCCTTACTTTGTTC
AAAATTTATTATAGTGGTTTAATCATTTTAGATTTGAATGTTTTAAGATAGGAGAGACTTAGCAGAAAATACTTGGCTTGCCAGGGCCAC
GTTCTACTTCATTGCTTTCTTTTATAAGTGCAAGGAGTTATTTCCATCAGTTGACATAGATATTATTCACTAAAATTTTCAGCAGACTCA
AAATAGAGAGGAGACTTTAAACTTACATGTTAGCATAAAACAGACTTCTCTCTCATTGCATGCACTAGATCAATATTATCATCTGTATTA
AGCTATCTGAATTTATTCGAGACATTAAGAAAAAGACAGTACATGGTGGGAAAGCTGCACATTTCTCACAAGGAAAAAAACATTCTATAT
TTGTAGCAGAAATCAGTGGTTTGAAAAGTCATACTTTGCAGATATGAACCTGAAAATCAAAGTGCCATTGTTAAATCATCCTAAAGTGTA
CTGTGGGTATTCTCCAGCATACTTGAAAATGAATAAAGTTAGATTGCTCACATTGAAGCTAATGGTTGAGACAAGACACCTGCCAGAGTG
AAGTTTGATTCCTATGGGTGAGAAGATGTAGATGACTATTGTTCTCACTAAAGTTCTAAAATAATAGCAAGTGTAGAGAAGAGCCGTTGC
TTTGAAAATACATACCACATTTGTTATAAAGCATTTGTTTGTTAGTATCAATCACATAGGTAGAAAGAGTTTGAGTTTTACTGTGGATTA
AAAAGCCTTCCCTAAAAAGAGAGCATGCCAGTCATAGAGACACTAATTTGGCACTTTTCCTCCTTCTTAGGTTTAAATGTTATACCAATG
CATGTGTTTGAAATATCCATTAAGATGATTTAAAATTTGTCTTGTATTTTGAGTTTCTTAAATGCGTGGATTCTTGTTCATTTATCTCTG
AATATGTCTCTTTTATATTTTGGCACAATTATACACATTGGAAAGGGCCAACCTATTAGGGCTCAAGTATGTATATGCAAAAAAAAAAAG
TTATATCAAACAGGCACAGTTATTACAACTAGAGAGAAATTCCAGAAATATTTGTTTTTTTAAGAGAAAGTAAATTTTCACATTAGATTT
CTATTCAAAGTACTAATATCTACATGGTCCACACTTTTCTATTTTAAAAAATTGTGTTCTCTTGTTAAATAGATTAACATTTCCACTTCT

>In-frame_ENST00000579180_ENST00000307142_TCGA-L3-A524-01A_MSI2_chr17_55478832_+_SYNPO2_chr4_119944585_length(amino acids)=1257AA_start in transcript=105_stop in transcript=3878
MVTRTKKIFVGGLSANTVVEDVKQYFEQFGKIRNQSKASGSGLCEGDEVVSINGNPCADLTYPEVIKLMESITDSLQMLIKRPSSGISEA
LISENENKNLEHLTHGGYVESTTLQIRPATKTQCTEFFLAPVKTEVPLAENQRSGPDCAGSLKEETGPSYQRAPQMPDSQRGRVAEELIL
REKVEAVQPGPVVELQLSLSQERHKGASGPLVALPGAEKSKSPDPDPNLSHDRIVHINSIPTNEKADPFLRSSKIIQISSGRELRVIQES
EAGDAGLPRVEVILDCSDRQKTEGCRLQAGKECVDSPVEGGQSEAPPSLVSFAVSSEGTEQGEDPRSEKDHSRPHKHRARHARLRRSESL
SEKQVKEAKSKCKSIALLLTDAPNPNSKGVLMFKKRRRRARKYTLVSYGTGELEREADEEEEGDKEDTCEVAFLGASESEVDEELLSDVD
DNTQVVNFDWDSGLVDIEKKLNRGDKMEMLPDTTGKGALMFAKRRERMDQITAQKEEDKVGGTPSREQDAAQTDGLRTTTSYQRKEEESV
RTQSSVSKSYIEVSHGLGHVPQQNGFSGTSETANIQRMVPMNRTAKPFPGSVNQPATPFSPTRNMTSPIADFPAPPPYSAVTPPPDAFSR
GVSSPIAGPAQPPPWPQPAPWSQPAFYDSSERIASRDERISVPAKRTGILQEAKRRSTTKPMFTFKEPKVSPNPELLSLLQNSEGKRGTG
AGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTPVSPVWSPGVAPTQPPAFPTSNPSKGTVVSSIKIAQPSYP
PARPASTLNVAGPFKGPQAAVASQNYTPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARAQSPT
PSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLNALDVMKHQPYQLNASLFTFQPPDAKDGLPQKSSV
KVNSALAMKQALPPRPVNAASPTNVQASSVYSVPAYTSPPSFFAEASSPVSASPVPVGIPTSPKQESASSSYFVAPRPKFSAKKSGVTIQ
ESGRSLSLPGRSVPPPISTSPWVYQPTYSYSSKPTDGLEKANKRPTPWEAAAKSPLGLVDDAFQPRNIQESIVANVVSAARRKVLPGPPE

--------------------------------------------------------------
>In-frame_ENST00000579180_ENST00000448416_TCGA-L3-A524-01A_MSI2_chr17_55478832_+_SYNPO2_chr4_119944585_length(transcript)=1242nt_BP=198nt
CAAGTCAGTCGATCCTGTGTTTGTGCTCCCGAAGGACTTGGCGACTTGGCTAACAAGGAGACATTTGTTATTTCATTTCCTCATCCATTA
TTCATGCAGTGAGAGATGGTCACAAGAACAAAGAAAATATTTGTAGGCGGGTTATCTGCGAACACAGTAGTGGAAGATGTAAAGCAATAT
TTCGAGCAGTTTGGCAAGATTCGAAATCAGAGCAAAGCCTCTGGGTCTGGGCTCTGTGAGGGAGATGAAGTGGTTTCCATCAATGGCAAC
CCTTGTGCAGATCTCACCTACCCTGAAGTCATCAAGCTCATGGAAAGCATAACAGACTCTCTCCAAATGCTCATCAAAAGGAGAGTGGGC
GCTCCCTTTCTCTTCCTGGAAGATCAGTCCCACCCCCCATTTCTACATCTCCTTGGGTATACCAGCCTACTTATAGTTACTCTAGTAAAC
CAACCGATGGACTAGAGAAAGCAAACAAGAGACCAACTCCTTGGGAAGCAGCAGCAAAGTCTCCTCTCGGTCTAGTGGATGATGCTTTCC
AACCCAGAAACATCCAGGAATCCATTGTGGCAAATGTGGTTTCAGCAGCTCGGAGGAAGGTGCTTCCAGGGCCTCCAGAGGATTGGAATG
AAAGACTGTCCTATATTCCTCAAACCCAGAAGGCCTATATGGGCTCATGTGGAAGGCAAGAGTATAATGTCACAGCCAATAATAATATGT
CCACCACCTCCCAATATGGTTCACAGTTGCCATATGCATATTATAGGCAGGCTTCAAGAAATGATTCTGCAATCATGTCCATGGAAACCA
GGTCTGATTACTGTCTTCCAGTAGCTGATTACAACTACAACCCACACCCAAGGGGATGGAGACGCCAAACATGAAAGTTAGAAGAACGGA
TCATGTGCCAACTGTAGTTTTTTAAAAAAAACGCTCCTTTGTAGGGTTTTAAACTTTTCTAATAGATTTAGATTCACTTTTGGTCTTGGC
TTGTTCTCATAAGTCATTTATCTAAGTTTGTGTTTCTGTGTGTGTGTGTGTGTGTGTATGTATGTGAATATACACACACACACACACACA
GGTGAGTGTGAATACTTCCTTGTTGGCTGATCCATAGAGCATTACTTGGAAGAAAATTTCACTATTTGCATTGATGTGCTGGCATTTATA

>In-frame_ENST00000579180_ENST00000448416_TCGA-L3-A524-01A_MSI2_chr17_55478832_+_SYNPO2_chr4_119944585_length(amino acids)=119AA_start in transcript=105_stop in transcript=464
MVTRTKKIFVGGLSANTVVEDVKQYFEQFGKIRNQSKASGSGLCEGDEVVSINGNPCADLTYPEVIKLMESITDSLQMLIKRRVGAPFLF

--------------------------------------------------------------
>In-frame_ENST00000579180_ENST00000429713_TCGA-L3-A524-01A_MSI2_chr17_55478832_+_SYNPO2_chr4_119944585_length(transcript)=7153nt_BP=198nt
CAAGTCAGTCGATCCTGTGTTTGTGCTCCCGAAGGACTTGGCGACTTGGCTAACAAGGAGACATTTGTTATTTCATTTCCTCATCCATTA
TTCATGCAGTGAGAGATGGTCACAAGAACAAAGAAAATATTTGTAGGCGGGTTATCTGCGAACACAGTAGTGGAAGATGTAAAGCAATAT
TTCGAGCAGTTTGGCAAGATTCGAAATCAGAGCAAAGCCTCTGGGTCTGGGCTCTGTGAGGGAGATGAAGTGGTTTCCATCAATGGCAAC
CCTTGTGCAGATCTCACCTACCCTGAAGTCATCAAGCTCATGGAAAGCATAACAGACTCTCTCCAAATGCTCATCAAAAGACCATCCAGT
GGAATAAGTGAGGCTTTGATATCTGAAAATGAAAACAAAAACCTCGAGCATCTCACACATGGGGGTTATGTGGAAAGTACCACCCTGCAG
ATTCGACCGGCCACAAAGACCCAGTGCACAGAATTCTTCCTCGCCCCTGTCAAGACTGAAGTTCCCCTAGCTGAGAACCAAAGAAGTGGT
CCCGACTGTGCAGGCAGCTTGAAAGAAGAAACAGGCCCGAGCTACCAAAGGGCTCCCCAAATGCCTGACTCCCAAAGAGGACGCGTGGCA
GAAGAGCTGATCTTAAGGGAGAAGGTAGAAGCGGTACAGCCTGGGCCTGTGGTTGAGCTGCAACTGTCCCTTTCACAGGAGAGACATAAG
GGCGCTAGTGGCCCTTTAGTGGCTCTCCCGGGAGCTGAAAAATCTAAGTCTCCTGACCCAGACCCTAACTTGTCACATGACAGGATTGTC
CACATAAATTCGATCCCTACTAATGAGAAAGCAGACCCTTTCCTGAGGTCCAGCAAGATAATCCAGATCTCCAGTGGCAGAGAGTTGAGA
GTGATCCAGGAAAGTGAAGCAGGAGATGCGGGACTGCCCCGGGTGGAAGTGATCCTCGACTGCTCTGACAGGCAGAAGACAGAAGGGTGC
AGGCTTCAGGCAGGAAAGGAGTGTGTGGATTCTCCAGTGGAAGGAGGGCAGTCAGAAGCACCTCCTTCTCTGGTATCCTTTGCCGTCTCA
TCAGAAGGCACAGAGCAGGGAGAAGATCCACGCTCGGAAAAAGATCACAGCAGACCTCACAAGCACCGAGCGCGGCATGCACGGCTCAGG
AGGAGTGAAAGCCTGTCAGAAAAACAAGTGAAGGAAGCAAAATCTAAATGCAAAAGCATTGCCCTTCTTCTAACGGATGCTCCCAACCCC
AACTCCAAGGGGGTGTTGATGTTTAAGAAGCGACGTCGGAGGGCCAGGAAATACACCCTAGTTAGCTACGGTACTGGCGAGCTTGAGCGA
GAGGCGGACGAGGAGGAAGAAGGTGACAAGGAGGATACATGTGAAGTAGCATTTCTTGGTGCAAGCGAATCAGAGGTGGATGAAGAGTTA
TTGTCTGACGTTGACGACAACACACAAGTTGTGAACTTTGACTGGGATTCTGGACTGGTGGACATTGAAAAGAAACTGAACAGAGGGGAC
AAGATGGAGATGTTACCAGACACCACAGGCAAGGGAGCCCTCATGTTTGCCAAGAGGAGGGAGAGAATGGATCAGATCACAGCCCAAAAA
GAAGAGGACAAGGTAGGTGGAACGCCAAGCAGAGAACAAGATGCTGCCCAGACCGATGGCCTGAGAACCACGACTTCTTACCAAAGAAAG
GAGGAAGAGTCGGTAAGAACGCAGAGCTCTGTGAGCAAAAGCTACATCGAGGTGAGTCATGGTCTTGGCCATGTTCCCCAACAGAATGGC
TTCAGTGGGACATCTGAGACAGCAAACATCCAGAGGATGGTCCCCATGAATAGAACGGCCAAACCCTTCCCAGGGTCTGTGAATCAGCCA
GCTACCCCCTTCTCGCCAACCCGAAACATGACGAGTCCCATTGCTGACTTTCCTGCACCTCCACCTTACTCTGCAGTCACTCCTCCCCCT
GACGCCTTCTCCAGAGGGGTTTCAAGTCCGATTGCTGGCCCAGCACAGCCCCCTCCATGGCCCCAGCCTGCCCCGTGGTCCCAGCCAGCC
TTTTACGATTCGTCTGAGCGAATAGCTTCCCGAGATGAGAGGATCTCAGTGCCAGCAAAAAGAACAGGAATATTGCAGGAGGCCAAAAGG
AGAAGCACGACAAAACCCATGTTTACTTTTAAAGAGCCCAAAGTAAGCCCAAATCCTGAACTCTTGTCACTCCTTCAAAATTCAGAAGGC
AAACGGGGCACTGGAGCTGGAGGTGATTCCGGACCGGAAGAAGACTACCTCAGCTTGGGGGCAGAGGCTTGTAATTTCATGCAAAGCTCC
TCTGCCAAACAAAAGACCCCTCCTCCTGTTGCTCCAAAACCTGCAGTCAAGTCCTCATCCTCCCAACCAGTAACTCCAGTTTCCCCAGTC
TGGTCTCCAGGAGTGGCTCCCACCCAACCTCCTGCCTTCCCCACATCCAACCCATCAAAGGGCACCGTTGTCTCCTCCATCAAAATAGCC
CAGCCTTCTTACCCTCCTGCCCGGCCTGCAAGTACTTTGAACGTGGCTGGTCCCTTCAAAGGACCACAAGCAGCAGTAGCCAGTCAGAAT
TACACACCCAAACCAACAGTTTCCACACCAACAGTCAATGCTGTTCAGCCTGGTGCAGTGGGACCATCCAATGAGCTTCCAGGAATGAGT
GGGAGAGGAGCTCAGCTCTTTGCTAAAAGGCAGTCGAGAATGGAGAAGTATGTGGTCGATTCAGACACGGTGCAGGCCCACGCTGCTCGA
GCTCAGTCTCCCACTCCATCTCTCCCGGCCAGTTGGAAGTACTCCTCCAATGTCCGAGCACCTCCTCCTGTGGCCTATAATCCTATCCAC
TCGCCGTCTTACCCACTGGCTGCTCTCAAGTCTCAGCCATCAGCTGCACAGCCCTCCAAAATGGGCAAGAAAAAGGGAAAGAAACCCCTC
AATGCATTAGATGTCATGAAGCACCAACCGTATCAGCTCAATGCATCCTTGTTTACTTTCCAACCTCCAGATGCAAAGGATGGCCTCCCC
CAGAAGTCATCAGTCAAGGTCAATTCAGCCCTGGCCATGAAGCAAGCTCTTCCTCCCCGGCCAGTGAATGCTGCCTCACCTACGAATGTG
CAGGCTTCGTCAGTGTACTCGGTACCAGCCTATACCTCTCCTCCTTCCTTCTTTGCAGAGGCCTCCTCACCAGTCAGTGCATCCCCAGTG
CCTGTGGGCATTCCCACCTCGCCAAAGCAAGAATCAGCCTCATCATCTTATTTTGTGGCACCAAGGCCAAAGTTCTCAGCCAAGAAAAGT
GGTGTCACAATTCAGGTGTGGAAACCATCTGTTGTGGAAGAGTAATCTTGTAGCTGAAGCTGAGTGTCCACTTTGCTTGAAATGAATTGT
TTGCAGTGTTTCTTGAGTCCCTGAGAATGCCTAGCAAAGTCCTCAACTTACTTAATTTCAGATATGTCACCTCCTAATCTGGGTCCAAGG
AGTATAATATTTTTAATGAGTCAAAAATCCAACTCAGATTGACCTAAAATATATTTATCTTCTTTGCACACTTAAAAAATCCAGGAGCAC
CCCAAAATAGACATGTACCGTTATATTAAGTAAGCAGGAGACTTAGGATTTGTGCTGTAGCCACAAGAAAGACAGTGATCAGTGATATCA
AACATCAGGAATCAGCCTTTATGTAACATAACAGCTGTCCTCCTATGGTGAAAGGTTCAAATGTAGTGAAGGTATAACCTATATTGACTG
AGATTTCCCTTTTAGGTAGTGCCTTATCTCTATTACTAGTGTTAAAGGAATAAGGAATCTATGAAGGACAGGGAGCAGCTCTGGTCTGTC
AATCTCAGCCACCTGTTTGATATCACAGAGAAGATACTCGGAGGATTGTTGGAATGTATATAGTTTAGTAAGAAGTGGGTAAGAAAGAGG
GTCTTAATTACTGAGCACTTATTATGTATTAGGTTCTTTGCCAGATGTTTTTACATATATAAACTCATTTCAGAAAACTTATTTAAAGTA
AATGGGGCCGGGTATGGTGGTTCATGCCTGGAATCCTAGCACTTTGGGAGGCTGAGGTAGGAGGACTGCTTGAGGCCGGGAGTTGGAGAC
CAGCCTGAGCAACATAGTGAGACCCTGTCTCAATAATAATAATAATAATAGTAATAATGAAGTAAATGGGATAAGGAAAGAAGGATAATT
ATCTTTAAAGGTTGATTCCCACCCTCCCTCCCCAGTTACTTAAGGAACTAAGTGAGTACATCTCCAGTTGCCCATGAAAGCATAAGTTTG
TTTTCCTCAGCTGAGGCAAGTGGTAGAGTATACAGGATAACGAAGTAACATGTAAAAGGCAGGACGCACATAAAGGTGTACATGGCTATT
GTTTCACCTGGAGAAACCACATGATTGGGACCTGAAGGTTTACTGACTGACTACAGGGGCTGATTGTGAAGCACGAGGAACCCCATGTGT
GTGGAGACTGTAGGGTGAGAGCACACAATTATTAGCATCATTTCTGAGTGATCTCACAGATTTTTTTTCTTGTGTTTGCTTTGCTTTTTG
ACAACTGCTTCTCCCACGTTCCTTGCAATTCTATTCTCTCACCTTCACTTTACTATTTGTATTCGATGGACCAGGATAATTCAGGCAAGG
TTACCTTGTAAACTTTAATTGGCCACACACCATGTTGTCACCCAGCTGGCTATGAAGTGAATAATGGTACTGAAAGTAAACCTGAAGACC
TTTCTCAGATCTATTTTAAGTCTGAGTCTGACCAACCATGGAAAATATTCGACATGAATTAATGTAGAGAACTATAAAGCATTTATGACA
GCTCCAAGAAAAATCATCTACTCTATGCAGGAGATATGTTTAGAGACCTCTCAGAAAAACTTGCCTGGTTTGAGGGTACACAGTACCATT
TTAATCTTCTGAAAATATCTGTATTCCTGCTCTTTTTCTGCTGTCACTGTCAATCTGCTATATTTTTCACTATCCTATTAAAATATTACT
GTCTCCTTTATCTGTTCAATGTCCATATTTTAAAAAAATCTTCCTTGTATGAGCTATTCTGATCTAAATAATTTCTCTGATATTTCTCTA
TATGGCTCCCACAACAATTTCATTGTTGTTAGCATATCTATTTCTCCATACATTGTAAAACTGTAATCCTTAGGTATTTCTAAAACATAA
AGAGGAGAATTAAGTCAGCTGCAGAACAATGGGGCTGATTCTTCTGCTTTTTCTCTGGAAAATCTTTCATTGCTTTTGGTGGAAATTTAC
CTAGAGGTTACAACCACAGGATGTAGCTTGGTCTCTTATTTGCCTTTTTGGGAAACCAATTAAGATTAATACAGGATAAAGGAAAAAAGC
AATCTATTCATTATATAACACAGTTGTTTGTATTACTTGTTCCCTGCAAAGGAAATCTGTTGAATGCTTGCATTTTGAATTCTTTTCTAA
TAGAACAACCAAAAAAGGCTTCTTATGGTGCAGCAGGAAAAAAGATCATTTTTATAGCTTTGCATTCTTAACATAGCATTTAAAGAGCGG
CATGAATTAGAGGAAAGACATGGAACACACAGGTAGTCGGTTTGAGATCATCGGCTTAAAAGTATCCTAGGATGGTAATGACCCAGAAGT
ATTTCCAGTTGTCTAGTGGTGTGGTATGCAGGAATGAGAAGTGTTTTCTTTCCATTTCCTGTTGGACAGGTGGCAATCTTAGCAGAGCCA
CTATTTGGAGTTGATAACTAAAGATGCAAATAACATGACTATGCCTTCTGGTCATCCTAGGACTATTTGGAGTTCTCCAAAACCTTGTAA
GAGGCATGTCAGGCATGCAGTAAAAGCATCTACAACTTCAGCTGGGCACTGGCAGCATAGGTCTCATCTTGGACCATACAGTCCCACTTT
ATAGAAGAGGGTGGAAGTTCTCCAAAACAATATCCACAACAAAGTCTGACCTCACTCTGAGGGAGATGGGAAGTGGGAGGAAGAAGGACT
AACCAGCTCCCTGGAGTAAGAGGAATTTGCTTTCCCTGTCTGCCCACCAGGGGCTATATGTGCCACCTTTCAGGTTGGGGCCAAGGAAGT
GATGTCAGTGTGACAGAAGGGAGAGTTAGACCTCCAGACGTCAGCCTCCCTCCCATGGGGTACATTTTCAATCTGAGTGTTGTTGCCTTA
GCTGTGTTGGTATTAGCTTGATTGGTTGGTCCGCTGGTTATGAGGTGTAGGGAGGCAGTTTTTGTTTAGTTTTTAGGACTTTGCCTCTTC
CTTTGTCCTTAGCATAATTTCTAGGCAGAGCATCCACGAAGTCGGTTTTCATTGCCAGCTCAAGAGCGACAATCATTTACGAGTTCCTAT
GTTATGTTAGGTGCCTTATGTATATTATCCCAAATCCACTGCATGGTTTAAATACAGGCACTGGAATATAAATGAAAAAGGTCATTACAG
TCACTGACTTTCTGCAGGACCTTAAACATTTCTCTTTCCACAAGTTTCCCCTTAATCATGTGTCAAACCTCTCTTCCTGACGGGAATGTT
GTGCTATAATGAATCTGCATAACGCTTGGGATTCTAGGAGGAAGGAAGGTTCCATGGACATGTAAGTACAGCATATTCCCCTCAGTCTTC
TAGGAGGGCAGAGTGAATCCCAGAACTGGTAAGATTGGGAATCTGAGCATTGCCACTTTAATCTTAGAATATTTATCATTTTGACACATC
CTGTTTTTTAGAGAGGAAAACAAACACAGTTTCTGCATTGGTAGTGTAAAGCATACCTTGTTAGGAACGTGTTTTGTAAGACACATTTGG
GTTGTCACTCTAGAGCATGTCAAACTTTGTACTTCAAAATATATTTAGTATGATTGTTAGTGGTAACATATATCAAGGCTTTGAATTAAC
TGTTTTATTTAATTTTCACAAGAAGCACTTATTTTAGCCATAGGAAAACCAATCTGAGCTACAAATAGTTCTTTAAAATAAGCCCAGGTT
ATTTAGCTATTCTAGAAAGTGCCGACTTCTTTCAAGAAGCAGGCATTGTAGGACAGCTGAGAATTATCACATAGCCTAAATTCTAGCCTG

>In-frame_ENST00000579180_ENST00000429713_TCGA-L3-A524-01A_MSI2_chr17_55478832_+_SYNPO2_chr4_119944585_length(amino acids)=1089AA_start in transcript=105_stop in transcript=3374
MVTRTKKIFVGGLSANTVVEDVKQYFEQFGKIRNQSKASGSGLCEGDEVVSINGNPCADLTYPEVIKLMESITDSLQMLIKRPSSGISEA
LISENENKNLEHLTHGGYVESTTLQIRPATKTQCTEFFLAPVKTEVPLAENQRSGPDCAGSLKEETGPSYQRAPQMPDSQRGRVAEELIL
REKVEAVQPGPVVELQLSLSQERHKGASGPLVALPGAEKSKSPDPDPNLSHDRIVHINSIPTNEKADPFLRSSKIIQISSGRELRVIQES
EAGDAGLPRVEVILDCSDRQKTEGCRLQAGKECVDSPVEGGQSEAPPSLVSFAVSSEGTEQGEDPRSEKDHSRPHKHRARHARLRRSESL
SEKQVKEAKSKCKSIALLLTDAPNPNSKGVLMFKKRRRRARKYTLVSYGTGELEREADEEEEGDKEDTCEVAFLGASESEVDEELLSDVD
DNTQVVNFDWDSGLVDIEKKLNRGDKMEMLPDTTGKGALMFAKRRERMDQITAQKEEDKVGGTPSREQDAAQTDGLRTTTSYQRKEEESV
RTQSSVSKSYIEVSHGLGHVPQQNGFSGTSETANIQRMVPMNRTAKPFPGSVNQPATPFSPTRNMTSPIADFPAPPPYSAVTPPPDAFSR
GVSSPIAGPAQPPPWPQPAPWSQPAFYDSSERIASRDERISVPAKRTGILQEAKRRSTTKPMFTFKEPKVSPNPELLSLLQNSEGKRGTG
AGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTPVSPVWSPGVAPTQPPAFPTSNPSKGTVVSSIKIAQPSYP
PARPASTLNVAGPFKGPQAAVASQNYTPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARAQSPT
PSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLNALDVMKHQPYQLNASLFTFQPPDAKDGLPQKSSV
KVNSALAMKQALPPRPVNAASPTNVQASSVYSVPAYTSPPSFFAEASSPVSASPVPVGIPTSPKQESASSSYFVAPRPKFSAKKSGVTIQ

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>In-frame_ENST00000579180_ENST00000434046_TCGA-L3-A524-01A_MSI2_chr17_55478832_+_SYNPO2_chr4_119944585_length(transcript)=3617nt_BP=198nt
CAAGTCAGTCGATCCTGTGTTTGTGCTCCCGAAGGACTTGGCGACTTGGCTAACAAGGAGACATTTGTTATTTCATTTCCTCATCCATTA
TTCATGCAGTGAGAGATGGTCACAAGAACAAAGAAAATATTTGTAGGCGGGTTATCTGCGAACACAGTAGTGGAAGATGTAAAGCAATAT
TTCGAGCAGTTTGGCAAGATTCGAAATCAGAGCAAAGCCTCTGGGTCTGGGCTCTGTGAGGGAGATGAAGTGGTTTCCATCAATGGCAAC
CCTTGTGCAGATCTCACCTACCCTGAAGTCATCAAGCTCATGGAAAGCATAACAGACTCTCTCCAAATGCTCATCAAAAGACCATCCAGT
GGAATAAGTGAGGCTTTGATATCTGAAAATGAAAACAAAAACCTCGAGCATCTCACACATGGGGGTTATGTGGAAAGTACCACCCTGCAG
ATTCGACCGGCCACAAAGACCCAGTGCACAGAATTCTTCCTCGCCCCTGTCAAGACTGAAGTTCCCCTAGCTGAGAACCAAAGAAGTGGT
CCCGACTGTGCAGGCAGCTTGAAAGAAGAAACAGGCCCGAGCTACCAAAGGGCTCCCCAAATGCCTGACTCCCAAAGAGGACGCGTGGCA
GAAGAGCTGATCTTAAGGGAGAAGGTAGAAGCGGTACAGCCTGGGCCTGTGGTTGAGCTGCAACTGTCCCTTTCACAGGAGAGACATAAG
GGCGCTAGTGGCCCTTTAGTGGCTCTCCCGGGAGCTGAAAAATCTAAGTCTCCTGACCCAGACCCTAACTTGTCACATGACAGGATTGTC
CACATAAATTCGATCCCTACTAATGAGAAAGCAGACCCTTTCCTGAGGTCCAGCAAGATAATCCAGATCTCCAGTGGCAGAGAGTTGAGA
GTGATCCAGGAAAGTGAAGCAGGAGATGCGGGACTGCCCCGGGTGGAAGTGATCCTCGACTGCTCTGACAGGCAGAAGACAGAAGGGTGC
AGGCTTCAGGCAGGAAAGGAGTGTGTGGATTCTCCAGTGGAAGGAGGGCAGTCAGAAGCACCTCCTTCTCTGGTATCCTTTGCCGTCTCA
TCAGAAGGCACAGAGCAGGGAGAAGATCCACGCTCGGAAAAAGATCACAGCAGACCTCACAAGCACCGAGCGCGGCATGCACGGCTCAGG
AGGAGTGAAAGCCTGTCAGAAAAACAAGTGAAGGAAGCAAAATCTAAATGCAAAAGCATTGCCCTTCTTCTAACGGATGCTCCCAACCCC
AACTCCAAGGGGGTGTTGATGTTTAAGAAGCGACGTCGGAGGGCCAGGAAATACACCCTAGTTAGCTACGGTACTGGCGAGCTTGAGCGA
GAGGCGGACGAGGAGGAAGAAGGTGACAAGGAGGATACATGTGAAGTAGCATTTCTTGGTGCAAGCGAATCAGAGGTGGATGAAGAGTTA
TTGTCTGACGTTGACGACAACACACAAGTTGTGAACTTTGACTGGGATTCTGGACTGGTGGACATTGAAAAGAAACTGAACAGAGGGGAC
AAGATGGAGATGTTACCAGACACCACAGGCAAGGGAGCCCTCATGTTTGCCAAGAGGAGGGAGAGAATGGATCAGATCACAGCCCAAAAA
GAAGAGGACAAGGTAGGTGGAACGCCAAGCAGAGAACAAGATGCTGCCCAGACCGATGGCCTGAGAACCACGACTTCTTACCAAAGAAAG
GAGGAAGAGTCGGTAAGAACGCAGAGCTCTGTGAGCAAAAGCTACATCGAGGTGAGTCATGGTCTTGGCCATGTTCCCCAACAGAATGGC
TTCAGTGGGACATCTGAGACAGCAAACATCCAGAGGATGGTCCCCATGAATAGAACGGCCAAACCCTTCCCAGGGTCTGTGAATCAGCCA
GCTACCCCCTTCTCGCCAACCCGAAACATGACGAGTCCCATTGCTGACTTTCCTGCACCTCCACCTTACTCTGCAGTCACTCCTCCCCCT
GACGCCTTCTCCAGAGGGGTTTCAAGTCCGATTGCTGGCCCAGCACAGCCCCCTCCATGGCCCCAGCCTGCCCCGTGGTCCCAGCCAGCC
TTTTACGATTCGTCTGAGCGAATAGCTTCCCGAGATGAGAGGATCTCAGTGCCAGCAAAAAGAACAGGAATATTGCAGGAGGCCAAAAGG
AGAAGCACGACAAAACCCATGTTTACTTTTAAAGAGCCCAAAGTAAGCCCAAATCCTGAACTCTTGTCACTCCTTCAAAATTCAGAAGGC
AAACGGGGCACTGGAGCTGGAGGTGATTCCGGACCGGAAGAAGACTACCTCAGCTTGGGGGCAGAGGCTTGTAATTTCATGCAAAGCTCC
TCTGCCAAACAAAAGACCCCTCCTCCTGTTGCTCCAAAACCTGCAGTCAAGTCCTCATCCTCCCAACCAGTAACTCCAGTTTCCCCAGTC
TGGTCTCCAGGAGTGGCTCCCACCCAACCTCCTGCCTTCCCCACATCCAACCCATCAAAGGGCACCGTTGTCTCCTCCATCAAAATAGCC
CAGCCTTCTTACCCTCCTGCCCGGCCTGCAAGTACTTTGAACGTGGCTGGTCCCTTCAAAGGACCACAAGCAGCAGTAGCCAGTCAGAAT
TACACACCCAAACCAACAGTTTCCACACCAACAGTCAATGCTGTTCAGCCTGGTGCAGTGGGACCATCCAATGAGCTTCCAGGAATGAGT
GGGAGAGGAGCTCAGCTCTTTGCTAAAAGGCAGTCGAGAATGGAGAAGTATGTGGTCGATTCAGACACGGTGCAGGCCCACGCTGCTCGA
GCTCAGTCTCCCACTCCATCTCTCCCGGCCAGTTGGAAGTACTCCTCCAATGTCCGAGCACCTCCTCCTGTGGCCTATAATCCTATCCAC
TCGCCGTCTTACCCACTGGCTGCTCTCAAGTCTCAGCCATCAGCTGCACAGCCCTCCAAAATGGGCAAGAAAAAGGGAAAGAAACCCCTC
AATGCATTAGATGTCATGAAGCACCAACCGTATCAGCTCAATGCATCCTTGTTTACTTTCCAACCTCCAGATGCAAAGGATGGCCTCCCC
CAGAAGTCATCAGTCAAGGTCAATTCAGCCCTGGCCATGAAGCAAGCTCTTCCTCCCCGGCCAGTGAATGCTGCCTCACCTACGAATGTG
CAGGCTTCGTCAGTGTACTCGGTACCAGCCTATACCTCTCCTCCTTCCTTCTTTGCAGAGGCCTCCTCACCAGTCAGTGCATCCCCAGTG
CCTGTGGGCATTCCCACCTCGCCAAAGCAAGAATCAGCCTCATCATCTTATTTTGTGGCACCAAGGCCAAAGTTCTCAGCCAAGAAAAGT
GGTGTCACAATTCAGGTGAAATGTAAATCTGGGATCCATAGTCAAGATATCATAAGGACCTACTTCCCAGCCTACCTTTCTTCCTCTACC
TGATAATGATAATACTCAAAATAACAACATTCAAAGGAAACACAAAGAAATCCTGCTTTCACATCTCCTATTTCTTGGGCTCCTTAATAA
CTACTGATGGTTTGTTCATGAAAAAAAATTTTTAAATCAAAAGATTGTACTTGGCCCTGAGTTGAAAAAATTTCAAAAATCAAAAGTTTG

>In-frame_ENST00000579180_ENST00000434046_TCGA-L3-A524-01A_MSI2_chr17_55478832_+_SYNPO2_chr4_119944585_length(amino acids)=1105AA_start in transcript=105_stop in transcript=3422
MVTRTKKIFVGGLSANTVVEDVKQYFEQFGKIRNQSKASGSGLCEGDEVVSINGNPCADLTYPEVIKLMESITDSLQMLIKRPSSGISEA
LISENENKNLEHLTHGGYVESTTLQIRPATKTQCTEFFLAPVKTEVPLAENQRSGPDCAGSLKEETGPSYQRAPQMPDSQRGRVAEELIL
REKVEAVQPGPVVELQLSLSQERHKGASGPLVALPGAEKSKSPDPDPNLSHDRIVHINSIPTNEKADPFLRSSKIIQISSGRELRVIQES
EAGDAGLPRVEVILDCSDRQKTEGCRLQAGKECVDSPVEGGQSEAPPSLVSFAVSSEGTEQGEDPRSEKDHSRPHKHRARHARLRRSESL
SEKQVKEAKSKCKSIALLLTDAPNPNSKGVLMFKKRRRRARKYTLVSYGTGELEREADEEEEGDKEDTCEVAFLGASESEVDEELLSDVD
DNTQVVNFDWDSGLVDIEKKLNRGDKMEMLPDTTGKGALMFAKRRERMDQITAQKEEDKVGGTPSREQDAAQTDGLRTTTSYQRKEEESV
RTQSSVSKSYIEVSHGLGHVPQQNGFSGTSETANIQRMVPMNRTAKPFPGSVNQPATPFSPTRNMTSPIADFPAPPPYSAVTPPPDAFSR
GVSSPIAGPAQPPPWPQPAPWSQPAFYDSSERIASRDERISVPAKRTGILQEAKRRSTTKPMFTFKEPKVSPNPELLSLLQNSEGKRGTG
AGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTPVSPVWSPGVAPTQPPAFPTSNPSKGTVVSSIKIAQPSYP
PARPASTLNVAGPFKGPQAAVASQNYTPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARAQSPT
PSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLNALDVMKHQPYQLNASLFTFQPPDAKDGLPQKSSV
KVNSALAMKQALPPRPVNAASPTNVQASSVYSVPAYTSPPSFFAEASSPVSASPVPVGIPTSPKQESASSSYFVAPRPKFSAKKSGVTIQ

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Fusion Gene PPI Analysis for MSI2-SYNPO2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneSYNPO2chr17:55478832chr4:119944585ENST0000030714205481_66335.01262.0ACTN2
TgeneSYNPO2chr17:55478832chr4:119944585ENST0000030714205664_92435.01262.0ACTN2
TgeneSYNPO2chr17:55478832chr4:119944585ENST0000030714205901_109335.01262.0ACTN2
TgeneSYNPO2chr17:55478832chr4:119944585ENST0000042971304481_66335.01094.0ACTN2
TgeneSYNPO2chr17:55478832chr4:119944585ENST0000042971304664_92435.01094.0ACTN2
TgeneSYNPO2chr17:55478832chr4:119944585ENST0000042971304901_109335.01094.0ACTN2
TgeneSYNPO2chr17:55478832chr4:119944585ENST0000043404605481_66335.01110.0ACTN2
TgeneSYNPO2chr17:55478832chr4:119944585ENST0000043404605664_92435.01110.0ACTN2
TgeneSYNPO2chr17:55478832chr4:119944585ENST0000043404605901_109335.01110.0ACTN2
TgeneSYNPO2chr17:55478832chr4:119944585ENST0000030714205615_62635.01262.0BAG3
TgeneSYNPO2chr17:55478832chr4:119944585ENST0000042971304615_62635.01094.0BAG3
TgeneSYNPO2chr17:55478832chr4:119944585ENST0000043404605615_62635.01110.0BAG3
TgeneSYNPO2chr17:55478832chr4:119944585ENST0000030714205810_109335.01262.0FLNC
TgeneSYNPO2chr17:55478832chr4:119944585ENST0000042971304810_109335.01094.0FLNC
TgeneSYNPO2chr17:55478832chr4:119944585ENST0000043404605810_109335.01110.0FLNC
TgeneSYNPO2chr17:55478832chr4:119944585ENST0000030714205607_81135.01262.0YWHAB
TgeneSYNPO2chr17:55478832chr4:119944585ENST0000042971304607_81135.01094.0YWHAB
TgeneSYNPO2chr17:55478832chr4:119944585ENST0000043404605607_81135.01110.0YWHAB
TgeneSYNPO2chr17:55478832chr4:119944585ENST00000307142051000_101935.01262.0ZYX
TgeneSYNPO2chr17:55478832chr4:119944585ENST00000429713041000_101935.01094.0ZYX
TgeneSYNPO2chr17:55478832chr4:119944585ENST00000434046051000_101935.01110.0ZYX


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
TgeneSYNPO2chr17:55478832chr4:119944585ENST00000307142051_18035.01262.0VPS18
TgeneSYNPO2chr17:55478832chr4:119944585ENST00000429713041_18035.01094.0VPS18
TgeneSYNPO2chr17:55478832chr4:119944585ENST00000434046051_18035.01110.0VPS18


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for MSI2-SYNPO2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for MSI2-SYNPO2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneSYNPO2C4721610Carcinoma, Ovarian Epithelial1CTD_human