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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:MTR-IFI16 (FusionGDB2 ID:55534)

Fusion Gene Summary for MTR-IFI16

check button Fusion gene summary
Fusion gene informationFusion gene name: MTR-IFI16
Fusion gene ID: 55534
HgeneTgene
Gene symbol

MTR

IFI16

Gene ID

4548

3428

Gene name5-methyltetrahydrofolate-homocysteine methyltransferaseinterferon gamma inducible protein 16
SynonymsHMAG|MS|cblGIFNGIP1|PYHIN2
Cytomap

1q43

1q23.1

Type of geneprotein-codingprotein-coding
Descriptionmethionine synthase5-methyltetrahydrofolate-homocysteine methyltransferase 1cobalamin-dependent methionine synthasevitamin-B12 dependent methionine synthasegamma-interferon-inducible protein 16IFI16 beta isoforminterferon-gamma induced protein IFI 16interferon-inducible myeloid differentiation transcriptional activator
Modification date2020031320200313
UniProtAcc.

Q16666

Ensembl transtripts involved in fusion geneENST00000366577, ENST00000418145, 
ENST00000535889, ENST00000470570, 
ENST00000340979, ENST00000368131, 
ENST00000368132, ENST00000295809, 
ENST00000430894, ENST00000359709, 
ENST00000448393, 
Fusion gene scores* DoF score6 X 6 X 3=10812 X 13 X 7=1092
# samples 715
** MAII scorelog2(7/108*10)=-0.625604485218502
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(15/1092*10)=-2.86393845042397
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: MTR [Title/Abstract] AND IFI16 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointMTR(237001899)-IFI16(159019222), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneIFI16

GO:0000122

negative regulation of transcription by RNA polymerase II

12894224|24413532

TgeneIFI16

GO:0002218

activation of innate immune response

21575908

TgeneIFI16

GO:0030224

monocyte differentiation

9766636

TgeneIFI16

GO:0032731

positive regulation of interleukin-1 beta production

21575908

TgeneIFI16

GO:0042149

cellular response to glucose starvation

21573174

TgeneIFI16

GO:0042771

intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

14654789

TgeneIFI16

GO:0043392

negative regulation of DNA binding

22291595

TgeneIFI16

GO:0045071

negative regulation of viral genome replication

22291595

TgeneIFI16

GO:0045824

negative regulation of innate immune response

22046441

TgeneIFI16

GO:0045892

negative regulation of transcription, DNA-templated

9642285

TgeneIFI16

GO:0045944

positive regulation of transcription by RNA polymerase II

11146555

TgeneIFI16

GO:0051607

defense response to virus

21478870

TgeneIFI16

GO:0071479

cellular response to ionizing radiation

14654789

TgeneIFI16

GO:2000117

negative regulation of cysteine-type endopeptidase activity

22046441


check buttonFusion gene breakpoints across MTR (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across IFI16 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-A8-A07O-01AMTRchr1

237001899

+IFI16chr1

159019222

+
ChimerDB4BRCATCGA-A8-A07OMTRchr1

237001899

+IFI16chr1

159015086

+
ChimerDB4BRCATCGA-A8-A07O-01AMTRchr1

237001899

+IFI16chr1

159019222

+
ChimerDB4BRCATCGA-A8-A07O-01AMTRchr1

237001899

-IFI16chr1

159021469

+


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Fusion Gene ORF analysis for MTR-IFI16

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000366577ENST00000340979MTRchr1

237001899

+IFI16chr1

159019222

+
5CDS-intronENST00000366577ENST00000368131MTRchr1

237001899

+IFI16chr1

159019222

+
5CDS-intronENST00000366577ENST00000368132MTRchr1

237001899

+IFI16chr1

159019222

+
5CDS-intronENST00000366577ENST00000295809MTRchr1

237001899

+IFI16chr1

159019222

+
5CDS-intronENST00000366577ENST00000430894MTRchr1

237001899

+IFI16chr1

159019222

+
5CDS-intronENST00000366577ENST00000359709MTRchr1

237001899

+IFI16chr1

159019222

+
5CDS-intronENST00000366577ENST00000448393MTRchr1

237001899

+IFI16chr1

159019222

+
intron-intronENST00000418145ENST00000340979MTRchr1

237001899

+IFI16chr1

159019222

+
intron-intronENST00000418145ENST00000368131MTRchr1

237001899

+IFI16chr1

159019222

+
intron-intronENST00000418145ENST00000368132MTRchr1

237001899

+IFI16chr1

159019222

+
intron-intronENST00000418145ENST00000295809MTRchr1

237001899

+IFI16chr1

159019222

+
intron-intronENST00000418145ENST00000430894MTRchr1

237001899

+IFI16chr1

159019222

+
intron-intronENST00000418145ENST00000359709MTRchr1

237001899

+IFI16chr1

159019222

+
intron-intronENST00000418145ENST00000448393MTRchr1

237001899

+IFI16chr1

159019222

+
5CDS-intronENST00000535889ENST00000340979MTRchr1

237001899

+IFI16chr1

159019222

+
5CDS-intronENST00000535889ENST00000368131MTRchr1

237001899

+IFI16chr1

159019222

+
5CDS-intronENST00000535889ENST00000368132MTRchr1

237001899

+IFI16chr1

159019222

+
5CDS-intronENST00000535889ENST00000295809MTRchr1

237001899

+IFI16chr1

159019222

+
5CDS-intronENST00000535889ENST00000430894MTRchr1

237001899

+IFI16chr1

159019222

+
5CDS-intronENST00000535889ENST00000359709MTRchr1

237001899

+IFI16chr1

159019222

+
5CDS-intronENST00000535889ENST00000448393MTRchr1

237001899

+IFI16chr1

159019222

+
intron-intronENST00000470570ENST00000340979MTRchr1

237001899

+IFI16chr1

159019222

+
intron-intronENST00000470570ENST00000368131MTRchr1

237001899

+IFI16chr1

159019222

+
intron-intronENST00000470570ENST00000368132MTRchr1

237001899

+IFI16chr1

159019222

+
intron-intronENST00000470570ENST00000295809MTRchr1

237001899

+IFI16chr1

159019222

+
intron-intronENST00000470570ENST00000430894MTRchr1

237001899

+IFI16chr1

159019222

+
intron-intronENST00000470570ENST00000359709MTRchr1

237001899

+IFI16chr1

159019222

+
intron-intronENST00000470570ENST00000448393MTRchr1

237001899

+IFI16chr1

159019222

+
5CDS-intronENST00000366577ENST00000340979MTRchr1

237001899

+IFI16chr1

159015086

+
5CDS-intronENST00000366577ENST00000368131MTRchr1

237001899

+IFI16chr1

159015086

+
5CDS-intronENST00000366577ENST00000368132MTRchr1

237001899

+IFI16chr1

159015086

+
5CDS-intronENST00000366577ENST00000295809MTRchr1

237001899

+IFI16chr1

159015086

+
5CDS-intronENST00000366577ENST00000430894MTRchr1

237001899

+IFI16chr1

159015086

+
5CDS-intronENST00000366577ENST00000359709MTRchr1

237001899

+IFI16chr1

159015086

+
5CDS-intronENST00000366577ENST00000448393MTRchr1

237001899

+IFI16chr1

159015086

+
intron-intronENST00000418145ENST00000340979MTRchr1

237001899

+IFI16chr1

159015086

+
intron-intronENST00000418145ENST00000368131MTRchr1

237001899

+IFI16chr1

159015086

+
intron-intronENST00000418145ENST00000368132MTRchr1

237001899

+IFI16chr1

159015086

+
intron-intronENST00000418145ENST00000295809MTRchr1

237001899

+IFI16chr1

159015086

+
intron-intronENST00000418145ENST00000430894MTRchr1

237001899

+IFI16chr1

159015086

+
intron-intronENST00000418145ENST00000359709MTRchr1

237001899

+IFI16chr1

159015086

+
intron-intronENST00000418145ENST00000448393MTRchr1

237001899

+IFI16chr1

159015086

+
5CDS-intronENST00000535889ENST00000340979MTRchr1

237001899

+IFI16chr1

159015086

+
5CDS-intronENST00000535889ENST00000368131MTRchr1

237001899

+IFI16chr1

159015086

+
5CDS-intronENST00000535889ENST00000368132MTRchr1

237001899

+IFI16chr1

159015086

+
5CDS-intronENST00000535889ENST00000295809MTRchr1

237001899

+IFI16chr1

159015086

+
5CDS-intronENST00000535889ENST00000430894MTRchr1

237001899

+IFI16chr1

159015086

+
5CDS-intronENST00000535889ENST00000359709MTRchr1

237001899

+IFI16chr1

159015086

+
5CDS-intronENST00000535889ENST00000448393MTRchr1

237001899

+IFI16chr1

159015086

+
intron-intronENST00000470570ENST00000340979MTRchr1

237001899

+IFI16chr1

159015086

+
intron-intronENST00000470570ENST00000368131MTRchr1

237001899

+IFI16chr1

159015086

+
intron-intronENST00000470570ENST00000368132MTRchr1

237001899

+IFI16chr1

159015086

+
intron-intronENST00000470570ENST00000295809MTRchr1

237001899

+IFI16chr1

159015086

+
intron-intronENST00000470570ENST00000430894MTRchr1

237001899

+IFI16chr1

159015086

+
intron-intronENST00000470570ENST00000359709MTRchr1

237001899

+IFI16chr1

159015086

+
intron-intronENST00000470570ENST00000448393MTRchr1

237001899

+IFI16chr1

159015086

+
In-frameENST00000366577ENST00000340979MTRchr1

237001899

-IFI16chr1

159021469

+
In-frameENST00000366577ENST00000368131MTRchr1

237001899

-IFI16chr1

159021469

+
In-frameENST00000366577ENST00000368132MTRchr1

237001899

-IFI16chr1

159021469

+
In-frameENST00000366577ENST00000295809MTRchr1

237001899

-IFI16chr1

159021469

+
In-frameENST00000366577ENST00000430894MTRchr1

237001899

-IFI16chr1

159021469

+
In-frameENST00000366577ENST00000359709MTRchr1

237001899

-IFI16chr1

159021469

+
In-frameENST00000366577ENST00000448393MTRchr1

237001899

-IFI16chr1

159021469

+
intron-3CDSENST00000418145ENST00000340979MTRchr1

237001899

-IFI16chr1

159021469

+
intron-3CDSENST00000418145ENST00000368131MTRchr1

237001899

-IFI16chr1

159021469

+
intron-3CDSENST00000418145ENST00000368132MTRchr1

237001899

-IFI16chr1

159021469

+
intron-3CDSENST00000418145ENST00000295809MTRchr1

237001899

-IFI16chr1

159021469

+
intron-3CDSENST00000418145ENST00000430894MTRchr1

237001899

-IFI16chr1

159021469

+
intron-3CDSENST00000418145ENST00000359709MTRchr1

237001899

-IFI16chr1

159021469

+
intron-3CDSENST00000418145ENST00000448393MTRchr1

237001899

-IFI16chr1

159021469

+
In-frameENST00000535889ENST00000340979MTRchr1

237001899

-IFI16chr1

159021469

+
In-frameENST00000535889ENST00000368131MTRchr1

237001899

-IFI16chr1

159021469

+
In-frameENST00000535889ENST00000368132MTRchr1

237001899

-IFI16chr1

159021469

+
In-frameENST00000535889ENST00000295809MTRchr1

237001899

-IFI16chr1

159021469

+
In-frameENST00000535889ENST00000430894MTRchr1

237001899

-IFI16chr1

159021469

+
In-frameENST00000535889ENST00000359709MTRchr1

237001899

-IFI16chr1

159021469

+
In-frameENST00000535889ENST00000448393MTRchr1

237001899

-IFI16chr1

159021469

+
intron-3CDSENST00000470570ENST00000340979MTRchr1

237001899

-IFI16chr1

159021469

+
intron-3CDSENST00000470570ENST00000368131MTRchr1

237001899

-IFI16chr1

159021469

+
intron-3CDSENST00000470570ENST00000368132MTRchr1

237001899

-IFI16chr1

159021469

+
intron-3CDSENST00000470570ENST00000295809MTRchr1

237001899

-IFI16chr1

159021469

+
intron-3CDSENST00000470570ENST00000430894MTRchr1

237001899

-IFI16chr1

159021469

+
intron-3CDSENST00000470570ENST00000359709MTRchr1

237001899

-IFI16chr1

159021469

+
intron-3CDSENST00000470570ENST00000448393MTRchr1

237001899

-IFI16chr1

159021469

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000366577MTRchr1237001899-ENST00000340979IFI16chr1159021469+285419093012601766
ENST00000366577MTRchr1237001899-ENST00000368131IFI16chr1159021469+285619093012601766
ENST00000366577MTRchr1237001899-ENST00000368132IFI16chr1159021469+285219093012601766
ENST00000366577MTRchr1237001899-ENST00000295809IFI16chr1159021469+285619093012601766
ENST00000366577MTRchr1237001899-ENST00000430894IFI16chr1159021469+284919093012601766
ENST00000366577MTRchr1237001899-ENST00000359709IFI16chr1159021469+284919093012601766
ENST00000366577MTRchr1237001899-ENST00000448393IFI16chr1159021469+282519093012601766
ENST00000535889MTRchr1237001899-ENST00000340979IFI16chr1159021469+24821537222229735
ENST00000535889MTRchr1237001899-ENST00000368131IFI16chr1159021469+24841537222229735
ENST00000535889MTRchr1237001899-ENST00000368132IFI16chr1159021469+24801537222229735
ENST00000535889MTRchr1237001899-ENST00000295809IFI16chr1159021469+24841537222229735
ENST00000535889MTRchr1237001899-ENST00000430894IFI16chr1159021469+24771537222229735
ENST00000535889MTRchr1237001899-ENST00000359709IFI16chr1159021469+24771537222229735
ENST00000535889MTRchr1237001899-ENST00000448393IFI16chr1159021469+24531537222229735

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000366577ENST00000340979MTRchr1237001899-IFI16chr1159021469+0.0009758120.99902415
ENST00000366577ENST00000368131MTRchr1237001899-IFI16chr1159021469+0.0009794420.9990206
ENST00000366577ENST00000368132MTRchr1237001899-IFI16chr1159021469+0.0009820960.99901783
ENST00000366577ENST00000295809MTRchr1237001899-IFI16chr1159021469+0.0009794420.9990206
ENST00000366577ENST00000430894MTRchr1237001899-IFI16chr1159021469+0.0009833990.99901664
ENST00000366577ENST00000359709MTRchr1237001899-IFI16chr1159021469+0.0009833990.99901664
ENST00000366577ENST00000448393MTRchr1237001899-IFI16chr1159021469+0.0011173780.9988826
ENST00000535889ENST00000340979MTRchr1237001899-IFI16chr1159021469+0.0008777910.9991222
ENST00000535889ENST00000368131MTRchr1237001899-IFI16chr1159021469+0.0008825240.99911743
ENST00000535889ENST00000368132MTRchr1237001899-IFI16chr1159021469+0.0008835610.9991165
ENST00000535889ENST00000295809MTRchr1237001899-IFI16chr1159021469+0.0008825240.99911743
ENST00000535889ENST00000430894MTRchr1237001899-IFI16chr1159021469+0.0008806990.99911934
ENST00000535889ENST00000359709MTRchr1237001899-IFI16chr1159021469+0.0008806990.99911934
ENST00000535889ENST00000448393MTRchr1237001899-IFI16chr1159021469+0.0010022310.99899775

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Fusion Genomic Features for MTR-IFI16


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for MTR-IFI16


check button Go to

FGviewer for the breakpoints of chr1:237001899-chr1:159021469

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.IFI16

Q16666

FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Binds double-stranded DNA. Binds preferentially to supercoiled DNA and cruciform DNA structures. Seems to be involved in transcriptional regulation. May function as a transcriptional repressor. Could have a role in the regulation of hematopoietic differentiation through activation of unknown target genes. Controls cellular proliferation by modulating the functions of cell cycle regulatory factors including p53/TP53 and the retinoblastoma protein. May be involved in TP53-mediated transcriptional activation by enhancing TP53 sequence-specific DNA binding and modulating TP53 phosphorylation status. Seems to be involved in energy-level-dependent activation of the ATM/ AMPK/TP53 pathway coupled to regulation of autophagy. May be involved in regulation of TP53-mediated cell death also involving BRCA1. May be involved in the senescence of prostate epithelial cells. Involved in innate immune response by recognizing viral dsDNA in the cytosol and probably in the nucleus. After binding to viral DNA in the cytoplasm recruits TMEM173/STING and mediates the induction of IFN-beta. Has anti-inflammatory activity and inhibits the activation of the AIM2 inflammasome, probably via association with AIM2. Proposed to bind viral DNA in the nucleus, such as of Kaposi's sarcoma-associated herpesvirus, and to induce the formation of nuclear caspase-1-activating inflammasome formation via association with PYCARD. Inhibits replication of herpesviruses such as human cytomegalovirus (HCMV) probably by interfering with promoter recruitment of members of the Sp1 family of transcription factors. Necessary to activate the IRF3 signaling cascade during human herpes simplex virus 1 (HHV-1) infection and promotes the assembly of heterochromatin on herpesviral DNA and inhibition of viral immediate-early gene expression and replication. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer. {ECO:0000269|PubMed:11146555, ECO:0000269|PubMed:12894224, ECO:0000269|PubMed:14654789, ECO:0000269|PubMed:20890285, ECO:0000269|PubMed:21573174, ECO:0000269|PubMed:21575908, ECO:0000269|PubMed:22046441, ECO:0000269|PubMed:22291595, ECO:0000269|PubMed:23027953, ECO:0000269|PubMed:24198334, ECO:0000269|PubMed:24413532, ECO:0000269|PubMed:9642285}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneMTRchr1:237001899chr1:159021469ENST00000366577-153319_338505.01266.0DomainHcy-binding
HgeneMTRchr1:237001899chr1:159021469ENST00000366577-1533382_384505.01266.0RegionSubstrate binding
TgeneIFI16chr1:237001899chr1:159021469ENST00000295809812562_761555.0786.0DomainHIN-200 2
TgeneIFI16chr1:237001899chr1:159021469ENST00000340979610562_761443.0674.0DomainHIN-200 2
TgeneIFI16chr1:237001899chr1:159021469ENST00000359709711562_761499.0730.0DomainHIN-200 2
TgeneIFI16chr1:237001899chr1:159021469ENST00000368131711562_761499.0730.0DomainHIN-200 2
TgeneIFI16chr1:237001899chr1:159021469ENST00000368132711562_761499.0730.0DomainHIN-200 2
TgeneIFI16chr1:237001899chr1:159021469ENST0000044839359562_761443.0674.0DomainHIN-200 2

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneMTRchr1:237001899chr1:159021469ENST00000366577-1533371_632505.01266.0DomainPterin-binding
HgeneMTRchr1:237001899chr1:159021469ENST00000366577-1533662_759505.01266.0DomainB12-binding N-terminal
HgeneMTRchr1:237001899chr1:159021469ENST00000366577-1533772_907505.01266.0DomainB12-binding
HgeneMTRchr1:237001899chr1:159021469ENST00000366577-1533923_1265505.01266.0DomainAdoMet activation
HgeneMTRchr1:237001899chr1:159021469ENST00000366577-15331227_1228505.01266.0RegionS-adenosyl-L-methionine binding
HgeneMTRchr1:237001899chr1:159021469ENST00000366577-1533782_786505.01266.0RegionMethylcob(III)alamin binding
TgeneIFI16chr1:237001899chr1:159021469ENST000002958098121_150555.0786.0Compositional biasNote=Lys-rich
TgeneIFI16chr1:237001899chr1:159021469ENST00000295809812258_261555.0786.0Compositional biasNote=Poly-Ile
TgeneIFI16chr1:237001899chr1:159021469ENST000003409796101_150443.0674.0Compositional biasNote=Lys-rich
TgeneIFI16chr1:237001899chr1:159021469ENST00000340979610258_261443.0674.0Compositional biasNote=Poly-Ile
TgeneIFI16chr1:237001899chr1:159021469ENST000003597097111_150499.0730.0Compositional biasNote=Lys-rich
TgeneIFI16chr1:237001899chr1:159021469ENST00000359709711258_261499.0730.0Compositional biasNote=Poly-Ile
TgeneIFI16chr1:237001899chr1:159021469ENST000003681317111_150499.0730.0Compositional biasNote=Lys-rich
TgeneIFI16chr1:237001899chr1:159021469ENST00000368131711258_261499.0730.0Compositional biasNote=Poly-Ile
TgeneIFI16chr1:237001899chr1:159021469ENST000003681327111_150499.0730.0Compositional biasNote=Lys-rich
TgeneIFI16chr1:237001899chr1:159021469ENST00000368132711258_261499.0730.0Compositional biasNote=Poly-Ile
TgeneIFI16chr1:237001899chr1:159021469ENST00000448393591_150443.0674.0Compositional biasNote=Lys-rich
TgeneIFI16chr1:237001899chr1:159021469ENST0000044839359258_261443.0674.0Compositional biasNote=Poly-Ile
TgeneIFI16chr1:237001899chr1:159021469ENST00000295809812189_389555.0786.0DomainHIN-200 1
TgeneIFI16chr1:237001899chr1:159021469ENST000002958098121_88555.0786.0DomainPyrin
TgeneIFI16chr1:237001899chr1:159021469ENST00000340979610189_389443.0674.0DomainHIN-200 1
TgeneIFI16chr1:237001899chr1:159021469ENST000003409796101_88443.0674.0DomainPyrin
TgeneIFI16chr1:237001899chr1:159021469ENST00000359709711189_389499.0730.0DomainHIN-200 1
TgeneIFI16chr1:237001899chr1:159021469ENST000003597097111_88499.0730.0DomainPyrin
TgeneIFI16chr1:237001899chr1:159021469ENST00000368131711189_389499.0730.0DomainHIN-200 1
TgeneIFI16chr1:237001899chr1:159021469ENST000003681317111_88499.0730.0DomainPyrin
TgeneIFI16chr1:237001899chr1:159021469ENST00000368132711189_389499.0730.0DomainHIN-200 1
TgeneIFI16chr1:237001899chr1:159021469ENST000003681327111_88499.0730.0DomainPyrin
TgeneIFI16chr1:237001899chr1:159021469ENST0000044839359189_389443.0674.0DomainHIN-200 1
TgeneIFI16chr1:237001899chr1:159021469ENST00000448393591_88443.0674.0DomainPyrin


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Fusion Gene Sequence for MTR-IFI16


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000366577_ENST00000340979_TCGA-A8-A07O-01A_MTR_chr1_237001899_-_IFI16_chr1_159021469_length(transcript)=2854nt_BP=1909nt
AAAGGTTCTAAATGTCTGCGGGGCTCAGAGCCGGATGTCACGTCGTCCTCCTCTGCCGGTTTTCTCTTGGGTCCTTTTCCGTGCCGTCCC
GCGACTCCGCCTCTGGCCGCGCGTGTCTGGCTGCTAGGCCGACACCAAGGACTGGCCGGGTACCCGGGAAGAAAGCACGTGCTCCAGCAG
TTGCCGCGCCCAGCCCCGAGAGAGGCCCTAGGGCGCTGCGGGCTTTCGGGGTCCGCAGTCCCCCCGCGACGCGAGCCAACGGGAGGCGTC
AAAAGACCCGGGCCTTGTGTGGCAGGCTCGCCTGGCGCTGGCTGGCGTGGCCCTTGGCCGTCGTCACCTGTGGAGAGCACGTCTTCTCTG
CCGCGCCCTCTGCGCAAGGAGGAGACTCGACAACATGTCACCCGCGCTCCAAGACCTGTCGCAACCCGAAGGTCTGAAGAAAACCCTGCG
GGATGAGATCAATGCCATTCTGCAGAAGAGGATTATGGTGCTGGATGGAGGGATGGGGACCATGATCCAGCGGGAGAAGCTAAACGAAGA
ACACTTCCGAGGTCAGGAATTTAAAGATCATGCCAGGCCGCTGAAAGGCAACAATGACATTTTAAGTATAACTCAGCCTGATGTCATTTA
CCAAATCCATAAGGAATACTTGCTGGCTGGGGCAGATATCATTGAAACAAATACTTTTAGCAGCACTAGTATTGCCCAAGCTGACTATGG
CCTTGAACACTTGGCCTACCGGATGAACATGTGCTCTGCAGGAGTGGCCAGAAAAGCTGCCGAGGAGGTAACTCTCCAGACAGGAATTAA
GAGGTTTGTGGCAGGGGCTCTGGGTCCGACTAATAAGACACTCTCTGTGTCCCCATCTGTGGAAAGGCCGGATTATAGGAACATCACATT
TGATGAGCTTGTTGAAGCATACCAAGAGCAGGCCAAAGGACTTCTGGATGGCGGGGTTGATATCTTACTCATTGAAACTATTTTTGATAC
TGCCAATGCCAAGGCAGCCTTGTTTGCACTCCAAAATCTTTTTGAGGAGAAATATGCTCCCCGGCCTATCTTTATTTCAGGGACGATCGT
TGATAAAAGTGGGCGGACTCTTTCCGGACAGACAGGAGAGGGATTTGTCATCAGCGTGTCTCATGGAGAACCACTCTGCATTGGATTAAA
TTGTGCTTTGGGTGCAGCTGAAATGAGACCTTTTATTGAAATAATTGGAAAATGTACAACAGCCTATGTCCTCTGTTATCCCAATGCAGG
TCTTCCCAACACCTTTGGTGACTATGATGAAACGCCTTCTATGATGGCCAAGCACCTAAAGGATTTTGCTATGGATGGCTTGGTCAATAT
AGTTGGAGGATGCTGTGGGTCAACACCAGATCATATCAGGGAAATTGCTGAAGCTGTGAAAAATTGTAAGCCTAGAGTTCCACCTGCCAC
TGCTTTTGAAGGACATATGTTACTGTCTGGTCTAGAGCCCTTCAGGATTGGACCGTACACCAACTTTGTTAACATTGGAGAGCGCTGTAA
TGTTGCAGGATCAAGGAAGTTTGCTAAACTCATCATGGCAGGAAACTATGAAGAAGCCTTGTGTGTTGCCAAAGTGCAGGTGGAAATGGG
AGCCCAGGTGTTGGATGTCAACATGGATGATGGCATGCTAGATGGTCCAAGTGCAATGACCAGATTTTGCAACTTAATTGCTTCCGAGCC
AGACATCGCAAAGGTACCTTTGTGCATCGACTCCTCCAATTTTGCTGTGATTGAAGCTGGGTTAAAGTGCTGCCAAGGGAAGTGCATTGT
CAATAGCATTAGTCTGAAGGAAGGAGAGGACGACTTCTTGGAGAAGGCCAGGAAGATTAAAAAGTATGGAGCTGCTATGGTGGTCATGGC
TTTTGATGAAGAAGGACAGTTGAAACCAAGACTGAAGACTGAACCTGAAGAAGTTTCCATAGAAGACAGTGCCCAGAGTGACCTCAAAGA
AGTGATGGTGCTGAACGCAACAGAATCATTTGTATATGAGCCCAAAGAGCAGAAGAAAATGTTTCATGCCACAGTGGCAACTGAGAATGA
AGTCTTCCGAGTGAAGGTTTTTAATATTGACCTAAAGGAGAAGTTCACCCCAAAGAAGATCATTGCCATAGCAAATTATGTTTGCCGCAA
TGGGTTCCTGGAGGTATATCCTTTCACACTTGTGGCTGATGTGAATGCTGACCGAAACATGGAGATCCCAAAAGGATTGATTAGAAGTGC
CAGCGTAACTCCTAAAATCAATCAGCTTTGCTCACAAACTAAAGGAAGTTTTGTGAATGGGGTGTTTGAGGTACATAAGAAAAATGTAAG
GGGTGAATTCACTTATTATGAAATACAAGATAATACAGGGAAGATGGAAGTGGTGGTGCATGGACGACTGACCACAATCAACTGTGAGGA
AGGAGATAAACTGAAACTCACCTGCTTTGAATTGGCACCGAAAAGTGGGAATACCGGGGAGTTGAGATCTGTAATTCATAGTCACATCAA
GGTCATCAAGACCAGGAAAAACAAGAAAGACATACTCAATCCTGATTCAAGTATGGAAACTTCACCAGACTTTTTCTTCTAAAATCTGGA
TGTCATTGACGATAATGTTTATGGAGATAAGGTCTAAGTGCCTAAAAAAATGTACATATACCTGGTTGAAATACAACACTATACATACAC
ACCACCATATATACTAGCTGTTAATCCTATGGAATGGGGTATTGGGAGTGCTTTTTTAATTTTTCATAGTTTTTTTTTAATAAAATGGCA

>In-frame_ENST00000366577_ENST00000340979_TCGA-A8-A07O-01A_MTR_chr1_237001899_-_IFI16_chr1_159021469_length(amino acids)=766AA_start in transcript=301_stop in transcript=2601
MALAGVALGRRHLWRARLLCRALCARRRLDNMSPALQDLSQPEGLKKTLRDEINAILQKRIMVLDGGMGTMIQREKLNEEHFRGQEFKDH
ARPLKGNNDILSITQPDVIYQIHKEYLLAGADIIETNTFSSTSIAQADYGLEHLAYRMNMCSAGVARKAAEEVTLQTGIKRFVAGALGPT
NKTLSVSPSVERPDYRNITFDELVEAYQEQAKGLLDGGVDILLIETIFDTANAKAALFALQNLFEEKYAPRPIFISGTIVDKSGRTLSGQ
TGEGFVISVSHGEPLCIGLNCALGAAEMRPFIEIIGKCTTAYVLCYPNAGLPNTFGDYDETPSMMAKHLKDFAMDGLVNIVGGCCGSTPD
HIREIAEAVKNCKPRVPPATAFEGHMLLSGLEPFRIGPYTNFVNIGERCNVAGSRKFAKLIMAGNYEEALCVAKVQVEMGAQVLDVNMDD
GMLDGPSAMTRFCNLIASEPDIAKVPLCIDSSNFAVIEAGLKCCQGKCIVNSISLKEGEDDFLEKARKIKKYGAAMVVMAFDEEGQLKPR
LKTEPEEVSIEDSAQSDLKEVMVLNATESFVYEPKEQKKMFHATVATENEVFRVKVFNIDLKEKFTPKKIIAIANYVCRNGFLEVYPFTL
VADVNADRNMEIPKGLIRSASVTPKINQLCSQTKGSFVNGVFEVHKKNVRGEFTYYEIQDNTGKMEVVVHGRLTTINCEEGDKLKLTCFE

--------------------------------------------------------------
>In-frame_ENST00000366577_ENST00000368131_TCGA-A8-A07O-01A_MTR_chr1_237001899_-_IFI16_chr1_159021469_length(transcript)=2856nt_BP=1909nt
AAAGGTTCTAAATGTCTGCGGGGCTCAGAGCCGGATGTCACGTCGTCCTCCTCTGCCGGTTTTCTCTTGGGTCCTTTTCCGTGCCGTCCC
GCGACTCCGCCTCTGGCCGCGCGTGTCTGGCTGCTAGGCCGACACCAAGGACTGGCCGGGTACCCGGGAAGAAAGCACGTGCTCCAGCAG
TTGCCGCGCCCAGCCCCGAGAGAGGCCCTAGGGCGCTGCGGGCTTTCGGGGTCCGCAGTCCCCCCGCGACGCGAGCCAACGGGAGGCGTC
AAAAGACCCGGGCCTTGTGTGGCAGGCTCGCCTGGCGCTGGCTGGCGTGGCCCTTGGCCGTCGTCACCTGTGGAGAGCACGTCTTCTCTG
CCGCGCCCTCTGCGCAAGGAGGAGACTCGACAACATGTCACCCGCGCTCCAAGACCTGTCGCAACCCGAAGGTCTGAAGAAAACCCTGCG
GGATGAGATCAATGCCATTCTGCAGAAGAGGATTATGGTGCTGGATGGAGGGATGGGGACCATGATCCAGCGGGAGAAGCTAAACGAAGA
ACACTTCCGAGGTCAGGAATTTAAAGATCATGCCAGGCCGCTGAAAGGCAACAATGACATTTTAAGTATAACTCAGCCTGATGTCATTTA
CCAAATCCATAAGGAATACTTGCTGGCTGGGGCAGATATCATTGAAACAAATACTTTTAGCAGCACTAGTATTGCCCAAGCTGACTATGG
CCTTGAACACTTGGCCTACCGGATGAACATGTGCTCTGCAGGAGTGGCCAGAAAAGCTGCCGAGGAGGTAACTCTCCAGACAGGAATTAA
GAGGTTTGTGGCAGGGGCTCTGGGTCCGACTAATAAGACACTCTCTGTGTCCCCATCTGTGGAAAGGCCGGATTATAGGAACATCACATT
TGATGAGCTTGTTGAAGCATACCAAGAGCAGGCCAAAGGACTTCTGGATGGCGGGGTTGATATCTTACTCATTGAAACTATTTTTGATAC
TGCCAATGCCAAGGCAGCCTTGTTTGCACTCCAAAATCTTTTTGAGGAGAAATATGCTCCCCGGCCTATCTTTATTTCAGGGACGATCGT
TGATAAAAGTGGGCGGACTCTTTCCGGACAGACAGGAGAGGGATTTGTCATCAGCGTGTCTCATGGAGAACCACTCTGCATTGGATTAAA
TTGTGCTTTGGGTGCAGCTGAAATGAGACCTTTTATTGAAATAATTGGAAAATGTACAACAGCCTATGTCCTCTGTTATCCCAATGCAGG
TCTTCCCAACACCTTTGGTGACTATGATGAAACGCCTTCTATGATGGCCAAGCACCTAAAGGATTTTGCTATGGATGGCTTGGTCAATAT
AGTTGGAGGATGCTGTGGGTCAACACCAGATCATATCAGGGAAATTGCTGAAGCTGTGAAAAATTGTAAGCCTAGAGTTCCACCTGCCAC
TGCTTTTGAAGGACATATGTTACTGTCTGGTCTAGAGCCCTTCAGGATTGGACCGTACACCAACTTTGTTAACATTGGAGAGCGCTGTAA
TGTTGCAGGATCAAGGAAGTTTGCTAAACTCATCATGGCAGGAAACTATGAAGAAGCCTTGTGTGTTGCCAAAGTGCAGGTGGAAATGGG
AGCCCAGGTGTTGGATGTCAACATGGATGATGGCATGCTAGATGGTCCAAGTGCAATGACCAGATTTTGCAACTTAATTGCTTCCGAGCC
AGACATCGCAAAGGTACCTTTGTGCATCGACTCCTCCAATTTTGCTGTGATTGAAGCTGGGTTAAAGTGCTGCCAAGGGAAGTGCATTGT
CAATAGCATTAGTCTGAAGGAAGGAGAGGACGACTTCTTGGAGAAGGCCAGGAAGATTAAAAAGTATGGAGCTGCTATGGTGGTCATGGC
TTTTGATGAAGAAGGACAGTTGAAACCAAGACTGAAGACTGAACCTGAAGAAGTTTCCATAGAAGACAGTGCCCAGAGTGACCTCAAAGA
AGTGATGGTGCTGAACGCAACAGAATCATTTGTATATGAGCCCAAAGAGCAGAAGAAAATGTTTCATGCCACAGTGGCAACTGAGAATGA
AGTCTTCCGAGTGAAGGTTTTTAATATTGACCTAAAGGAGAAGTTCACCCCAAAGAAGATCATTGCCATAGCAAATTATGTTTGCCGCAA
TGGGTTCCTGGAGGTATATCCTTTCACACTTGTGGCTGATGTGAATGCTGACCGAAACATGGAGATCCCAAAAGGATTGATTAGAAGTGC
CAGCGTAACTCCTAAAATCAATCAGCTTTGCTCACAAACTAAAGGAAGTTTTGTGAATGGGGTGTTTGAGGTACATAAGAAAAATGTAAG
GGGTGAATTCACTTATTATGAAATACAAGATAATACAGGGAAGATGGAAGTGGTGGTGCATGGACGACTGACCACAATCAACTGTGAGGA
AGGAGATAAACTGAAACTCACCTGCTTTGAATTGGCACCGAAAAGTGGGAATACCGGGGAGTTGAGATCTGTAATTCATAGTCACATCAA
GGTCATCAAGACCAGGAAAAACAAGAAAGACATACTCAATCCTGATTCAAGTATGGAAACTTCACCAGACTTTTTCTTCTAAAATCTGGA
TGTCATTGACGATAATGTTTATGGAGATAAGGTCTAAGTGCCTAAAAAAATGTACATATACCTGGTTGAAATACAACACTATACATACAC
ACCACCATATATACTAGCTGTTAATCCTATGGAATGGGGTATTGGGAGTGCTTTTTTAATTTTTCATAGTTTTTTTTTAATAAAATGGCA

>In-frame_ENST00000366577_ENST00000368131_TCGA-A8-A07O-01A_MTR_chr1_237001899_-_IFI16_chr1_159021469_length(amino acids)=766AA_start in transcript=301_stop in transcript=2601
MALAGVALGRRHLWRARLLCRALCARRRLDNMSPALQDLSQPEGLKKTLRDEINAILQKRIMVLDGGMGTMIQREKLNEEHFRGQEFKDH
ARPLKGNNDILSITQPDVIYQIHKEYLLAGADIIETNTFSSTSIAQADYGLEHLAYRMNMCSAGVARKAAEEVTLQTGIKRFVAGALGPT
NKTLSVSPSVERPDYRNITFDELVEAYQEQAKGLLDGGVDILLIETIFDTANAKAALFALQNLFEEKYAPRPIFISGTIVDKSGRTLSGQ
TGEGFVISVSHGEPLCIGLNCALGAAEMRPFIEIIGKCTTAYVLCYPNAGLPNTFGDYDETPSMMAKHLKDFAMDGLVNIVGGCCGSTPD
HIREIAEAVKNCKPRVPPATAFEGHMLLSGLEPFRIGPYTNFVNIGERCNVAGSRKFAKLIMAGNYEEALCVAKVQVEMGAQVLDVNMDD
GMLDGPSAMTRFCNLIASEPDIAKVPLCIDSSNFAVIEAGLKCCQGKCIVNSISLKEGEDDFLEKARKIKKYGAAMVVMAFDEEGQLKPR
LKTEPEEVSIEDSAQSDLKEVMVLNATESFVYEPKEQKKMFHATVATENEVFRVKVFNIDLKEKFTPKKIIAIANYVCRNGFLEVYPFTL
VADVNADRNMEIPKGLIRSASVTPKINQLCSQTKGSFVNGVFEVHKKNVRGEFTYYEIQDNTGKMEVVVHGRLTTINCEEGDKLKLTCFE

--------------------------------------------------------------
>In-frame_ENST00000366577_ENST00000368132_TCGA-A8-A07O-01A_MTR_chr1_237001899_-_IFI16_chr1_159021469_length(transcript)=2852nt_BP=1909nt
AAAGGTTCTAAATGTCTGCGGGGCTCAGAGCCGGATGTCACGTCGTCCTCCTCTGCCGGTTTTCTCTTGGGTCCTTTTCCGTGCCGTCCC
GCGACTCCGCCTCTGGCCGCGCGTGTCTGGCTGCTAGGCCGACACCAAGGACTGGCCGGGTACCCGGGAAGAAAGCACGTGCTCCAGCAG
TTGCCGCGCCCAGCCCCGAGAGAGGCCCTAGGGCGCTGCGGGCTTTCGGGGTCCGCAGTCCCCCCGCGACGCGAGCCAACGGGAGGCGTC
AAAAGACCCGGGCCTTGTGTGGCAGGCTCGCCTGGCGCTGGCTGGCGTGGCCCTTGGCCGTCGTCACCTGTGGAGAGCACGTCTTCTCTG
CCGCGCCCTCTGCGCAAGGAGGAGACTCGACAACATGTCACCCGCGCTCCAAGACCTGTCGCAACCCGAAGGTCTGAAGAAAACCCTGCG
GGATGAGATCAATGCCATTCTGCAGAAGAGGATTATGGTGCTGGATGGAGGGATGGGGACCATGATCCAGCGGGAGAAGCTAAACGAAGA
ACACTTCCGAGGTCAGGAATTTAAAGATCATGCCAGGCCGCTGAAAGGCAACAATGACATTTTAAGTATAACTCAGCCTGATGTCATTTA
CCAAATCCATAAGGAATACTTGCTGGCTGGGGCAGATATCATTGAAACAAATACTTTTAGCAGCACTAGTATTGCCCAAGCTGACTATGG
CCTTGAACACTTGGCCTACCGGATGAACATGTGCTCTGCAGGAGTGGCCAGAAAAGCTGCCGAGGAGGTAACTCTCCAGACAGGAATTAA
GAGGTTTGTGGCAGGGGCTCTGGGTCCGACTAATAAGACACTCTCTGTGTCCCCATCTGTGGAAAGGCCGGATTATAGGAACATCACATT
TGATGAGCTTGTTGAAGCATACCAAGAGCAGGCCAAAGGACTTCTGGATGGCGGGGTTGATATCTTACTCATTGAAACTATTTTTGATAC
TGCCAATGCCAAGGCAGCCTTGTTTGCACTCCAAAATCTTTTTGAGGAGAAATATGCTCCCCGGCCTATCTTTATTTCAGGGACGATCGT
TGATAAAAGTGGGCGGACTCTTTCCGGACAGACAGGAGAGGGATTTGTCATCAGCGTGTCTCATGGAGAACCACTCTGCATTGGATTAAA
TTGTGCTTTGGGTGCAGCTGAAATGAGACCTTTTATTGAAATAATTGGAAAATGTACAACAGCCTATGTCCTCTGTTATCCCAATGCAGG
TCTTCCCAACACCTTTGGTGACTATGATGAAACGCCTTCTATGATGGCCAAGCACCTAAAGGATTTTGCTATGGATGGCTTGGTCAATAT
AGTTGGAGGATGCTGTGGGTCAACACCAGATCATATCAGGGAAATTGCTGAAGCTGTGAAAAATTGTAAGCCTAGAGTTCCACCTGCCAC
TGCTTTTGAAGGACATATGTTACTGTCTGGTCTAGAGCCCTTCAGGATTGGACCGTACACCAACTTTGTTAACATTGGAGAGCGCTGTAA
TGTTGCAGGATCAAGGAAGTTTGCTAAACTCATCATGGCAGGAAACTATGAAGAAGCCTTGTGTGTTGCCAAAGTGCAGGTGGAAATGGG
AGCCCAGGTGTTGGATGTCAACATGGATGATGGCATGCTAGATGGTCCAAGTGCAATGACCAGATTTTGCAACTTAATTGCTTCCGAGCC
AGACATCGCAAAGGTACCTTTGTGCATCGACTCCTCCAATTTTGCTGTGATTGAAGCTGGGTTAAAGTGCTGCCAAGGGAAGTGCATTGT
CAATAGCATTAGTCTGAAGGAAGGAGAGGACGACTTCTTGGAGAAGGCCAGGAAGATTAAAAAGTATGGAGCTGCTATGGTGGTCATGGC
TTTTGATGAAGAAGGACAGTTGAAACCAAGACTGAAGACTGAACCTGAAGAAGTTTCCATAGAAGACAGTGCCCAGAGTGACCTCAAAGA
AGTGATGGTGCTGAACGCAACAGAATCATTTGTATATGAGCCCAAAGAGCAGAAGAAAATGTTTCATGCCACAGTGGCAACTGAGAATGA
AGTCTTCCGAGTGAAGGTTTTTAATATTGACCTAAAGGAGAAGTTCACCCCAAAGAAGATCATTGCCATAGCAAATTATGTTTGCCGCAA
TGGGTTCCTGGAGGTATATCCTTTCACACTTGTGGCTGATGTGAATGCTGACCGAAACATGGAGATCCCAAAAGGATTGATTAGAAGTGC
CAGCGTAACTCCTAAAATCAATCAGCTTTGCTCACAAACTAAAGGAAGTTTTGTGAATGGGGTGTTTGAGGTACATAAGAAAAATGTAAG
GGGTGAATTCACTTATTATGAAATACAAGATAATACAGGGAAGATGGAAGTGGTGGTGCATGGACGACTGACCACAATCAACTGTGAGGA
AGGAGATAAACTGAAACTCACCTGCTTTGAATTGGCACCGAAAAGTGGGAATACCGGGGAGTTGAGATCTGTAATTCATAGTCACATCAA
GGTCATCAAGACCAGGAAAAACAAGAAAGACATACTCAATCCTGATTCAAGTATGGAAACTTCACCAGACTTTTTCTTCTAAAATCTGGA
TGTCATTGACGATAATGTTTATGGAGATAAGGTCTAAGTGCCTAAAAAAATGTACATATACCTGGTTGAAATACAACACTATACATACAC
ACCACCATATATACTAGCTGTTAATCCTATGGAATGGGGTATTGGGAGTGCTTTTTTAATTTTTCATAGTTTTTTTTTAATAAAATGGCA

>In-frame_ENST00000366577_ENST00000368132_TCGA-A8-A07O-01A_MTR_chr1_237001899_-_IFI16_chr1_159021469_length(amino acids)=766AA_start in transcript=301_stop in transcript=2601
MALAGVALGRRHLWRARLLCRALCARRRLDNMSPALQDLSQPEGLKKTLRDEINAILQKRIMVLDGGMGTMIQREKLNEEHFRGQEFKDH
ARPLKGNNDILSITQPDVIYQIHKEYLLAGADIIETNTFSSTSIAQADYGLEHLAYRMNMCSAGVARKAAEEVTLQTGIKRFVAGALGPT
NKTLSVSPSVERPDYRNITFDELVEAYQEQAKGLLDGGVDILLIETIFDTANAKAALFALQNLFEEKYAPRPIFISGTIVDKSGRTLSGQ
TGEGFVISVSHGEPLCIGLNCALGAAEMRPFIEIIGKCTTAYVLCYPNAGLPNTFGDYDETPSMMAKHLKDFAMDGLVNIVGGCCGSTPD
HIREIAEAVKNCKPRVPPATAFEGHMLLSGLEPFRIGPYTNFVNIGERCNVAGSRKFAKLIMAGNYEEALCVAKVQVEMGAQVLDVNMDD
GMLDGPSAMTRFCNLIASEPDIAKVPLCIDSSNFAVIEAGLKCCQGKCIVNSISLKEGEDDFLEKARKIKKYGAAMVVMAFDEEGQLKPR
LKTEPEEVSIEDSAQSDLKEVMVLNATESFVYEPKEQKKMFHATVATENEVFRVKVFNIDLKEKFTPKKIIAIANYVCRNGFLEVYPFTL
VADVNADRNMEIPKGLIRSASVTPKINQLCSQTKGSFVNGVFEVHKKNVRGEFTYYEIQDNTGKMEVVVHGRLTTINCEEGDKLKLTCFE

--------------------------------------------------------------
>In-frame_ENST00000366577_ENST00000295809_TCGA-A8-A07O-01A_MTR_chr1_237001899_-_IFI16_chr1_159021469_length(transcript)=2856nt_BP=1909nt
AAAGGTTCTAAATGTCTGCGGGGCTCAGAGCCGGATGTCACGTCGTCCTCCTCTGCCGGTTTTCTCTTGGGTCCTTTTCCGTGCCGTCCC
GCGACTCCGCCTCTGGCCGCGCGTGTCTGGCTGCTAGGCCGACACCAAGGACTGGCCGGGTACCCGGGAAGAAAGCACGTGCTCCAGCAG
TTGCCGCGCCCAGCCCCGAGAGAGGCCCTAGGGCGCTGCGGGCTTTCGGGGTCCGCAGTCCCCCCGCGACGCGAGCCAACGGGAGGCGTC
AAAAGACCCGGGCCTTGTGTGGCAGGCTCGCCTGGCGCTGGCTGGCGTGGCCCTTGGCCGTCGTCACCTGTGGAGAGCACGTCTTCTCTG
CCGCGCCCTCTGCGCAAGGAGGAGACTCGACAACATGTCACCCGCGCTCCAAGACCTGTCGCAACCCGAAGGTCTGAAGAAAACCCTGCG
GGATGAGATCAATGCCATTCTGCAGAAGAGGATTATGGTGCTGGATGGAGGGATGGGGACCATGATCCAGCGGGAGAAGCTAAACGAAGA
ACACTTCCGAGGTCAGGAATTTAAAGATCATGCCAGGCCGCTGAAAGGCAACAATGACATTTTAAGTATAACTCAGCCTGATGTCATTTA
CCAAATCCATAAGGAATACTTGCTGGCTGGGGCAGATATCATTGAAACAAATACTTTTAGCAGCACTAGTATTGCCCAAGCTGACTATGG
CCTTGAACACTTGGCCTACCGGATGAACATGTGCTCTGCAGGAGTGGCCAGAAAAGCTGCCGAGGAGGTAACTCTCCAGACAGGAATTAA
GAGGTTTGTGGCAGGGGCTCTGGGTCCGACTAATAAGACACTCTCTGTGTCCCCATCTGTGGAAAGGCCGGATTATAGGAACATCACATT
TGATGAGCTTGTTGAAGCATACCAAGAGCAGGCCAAAGGACTTCTGGATGGCGGGGTTGATATCTTACTCATTGAAACTATTTTTGATAC
TGCCAATGCCAAGGCAGCCTTGTTTGCACTCCAAAATCTTTTTGAGGAGAAATATGCTCCCCGGCCTATCTTTATTTCAGGGACGATCGT
TGATAAAAGTGGGCGGACTCTTTCCGGACAGACAGGAGAGGGATTTGTCATCAGCGTGTCTCATGGAGAACCACTCTGCATTGGATTAAA
TTGTGCTTTGGGTGCAGCTGAAATGAGACCTTTTATTGAAATAATTGGAAAATGTACAACAGCCTATGTCCTCTGTTATCCCAATGCAGG
TCTTCCCAACACCTTTGGTGACTATGATGAAACGCCTTCTATGATGGCCAAGCACCTAAAGGATTTTGCTATGGATGGCTTGGTCAATAT
AGTTGGAGGATGCTGTGGGTCAACACCAGATCATATCAGGGAAATTGCTGAAGCTGTGAAAAATTGTAAGCCTAGAGTTCCACCTGCCAC
TGCTTTTGAAGGACATATGTTACTGTCTGGTCTAGAGCCCTTCAGGATTGGACCGTACACCAACTTTGTTAACATTGGAGAGCGCTGTAA
TGTTGCAGGATCAAGGAAGTTTGCTAAACTCATCATGGCAGGAAACTATGAAGAAGCCTTGTGTGTTGCCAAAGTGCAGGTGGAAATGGG
AGCCCAGGTGTTGGATGTCAACATGGATGATGGCATGCTAGATGGTCCAAGTGCAATGACCAGATTTTGCAACTTAATTGCTTCCGAGCC
AGACATCGCAAAGGTACCTTTGTGCATCGACTCCTCCAATTTTGCTGTGATTGAAGCTGGGTTAAAGTGCTGCCAAGGGAAGTGCATTGT
CAATAGCATTAGTCTGAAGGAAGGAGAGGACGACTTCTTGGAGAAGGCCAGGAAGATTAAAAAGTATGGAGCTGCTATGGTGGTCATGGC
TTTTGATGAAGAAGGACAGTTGAAACCAAGACTGAAGACTGAACCTGAAGAAGTTTCCATAGAAGACAGTGCCCAGAGTGACCTCAAAGA
AGTGATGGTGCTGAACGCAACAGAATCATTTGTATATGAGCCCAAAGAGCAGAAGAAAATGTTTCATGCCACAGTGGCAACTGAGAATGA
AGTCTTCCGAGTGAAGGTTTTTAATATTGACCTAAAGGAGAAGTTCACCCCAAAGAAGATCATTGCCATAGCAAATTATGTTTGCCGCAA
TGGGTTCCTGGAGGTATATCCTTTCACACTTGTGGCTGATGTGAATGCTGACCGAAACATGGAGATCCCAAAAGGATTGATTAGAAGTGC
CAGCGTAACTCCTAAAATCAATCAGCTTTGCTCACAAACTAAAGGAAGTTTTGTGAATGGGGTGTTTGAGGTACATAAGAAAAATGTAAG
GGGTGAATTCACTTATTATGAAATACAAGATAATACAGGGAAGATGGAAGTGGTGGTGCATGGACGACTGACCACAATCAACTGTGAGGA
AGGAGATAAACTGAAACTCACCTGCTTTGAATTGGCACCGAAAAGTGGGAATACCGGGGAGTTGAGATCTGTAATTCATAGTCACATCAA
GGTCATCAAGACCAGGAAAAACAAGAAAGACATACTCAATCCTGATTCAAGTATGGAAACTTCACCAGACTTTTTCTTCTAAAATCTGGA
TGTCATTGACGATAATGTTTATGGAGATAAGGTCTAAGTGCCTAAAAAAATGTACATATACCTGGTTGAAATACAACACTATACATACAC
ACCACCATATATACTAGCTGTTAATCCTATGGAATGGGGTATTGGGAGTGCTTTTTTAATTTTTCATAGTTTTTTTTTAATAAAATGGCA

>In-frame_ENST00000366577_ENST00000295809_TCGA-A8-A07O-01A_MTR_chr1_237001899_-_IFI16_chr1_159021469_length(amino acids)=766AA_start in transcript=301_stop in transcript=2601
MALAGVALGRRHLWRARLLCRALCARRRLDNMSPALQDLSQPEGLKKTLRDEINAILQKRIMVLDGGMGTMIQREKLNEEHFRGQEFKDH
ARPLKGNNDILSITQPDVIYQIHKEYLLAGADIIETNTFSSTSIAQADYGLEHLAYRMNMCSAGVARKAAEEVTLQTGIKRFVAGALGPT
NKTLSVSPSVERPDYRNITFDELVEAYQEQAKGLLDGGVDILLIETIFDTANAKAALFALQNLFEEKYAPRPIFISGTIVDKSGRTLSGQ
TGEGFVISVSHGEPLCIGLNCALGAAEMRPFIEIIGKCTTAYVLCYPNAGLPNTFGDYDETPSMMAKHLKDFAMDGLVNIVGGCCGSTPD
HIREIAEAVKNCKPRVPPATAFEGHMLLSGLEPFRIGPYTNFVNIGERCNVAGSRKFAKLIMAGNYEEALCVAKVQVEMGAQVLDVNMDD
GMLDGPSAMTRFCNLIASEPDIAKVPLCIDSSNFAVIEAGLKCCQGKCIVNSISLKEGEDDFLEKARKIKKYGAAMVVMAFDEEGQLKPR
LKTEPEEVSIEDSAQSDLKEVMVLNATESFVYEPKEQKKMFHATVATENEVFRVKVFNIDLKEKFTPKKIIAIANYVCRNGFLEVYPFTL
VADVNADRNMEIPKGLIRSASVTPKINQLCSQTKGSFVNGVFEVHKKNVRGEFTYYEIQDNTGKMEVVVHGRLTTINCEEGDKLKLTCFE

--------------------------------------------------------------
>In-frame_ENST00000366577_ENST00000430894_TCGA-A8-A07O-01A_MTR_chr1_237001899_-_IFI16_chr1_159021469_length(transcript)=2849nt_BP=1909nt
AAAGGTTCTAAATGTCTGCGGGGCTCAGAGCCGGATGTCACGTCGTCCTCCTCTGCCGGTTTTCTCTTGGGTCCTTTTCCGTGCCGTCCC
GCGACTCCGCCTCTGGCCGCGCGTGTCTGGCTGCTAGGCCGACACCAAGGACTGGCCGGGTACCCGGGAAGAAAGCACGTGCTCCAGCAG
TTGCCGCGCCCAGCCCCGAGAGAGGCCCTAGGGCGCTGCGGGCTTTCGGGGTCCGCAGTCCCCCCGCGACGCGAGCCAACGGGAGGCGTC
AAAAGACCCGGGCCTTGTGTGGCAGGCTCGCCTGGCGCTGGCTGGCGTGGCCCTTGGCCGTCGTCACCTGTGGAGAGCACGTCTTCTCTG
CCGCGCCCTCTGCGCAAGGAGGAGACTCGACAACATGTCACCCGCGCTCCAAGACCTGTCGCAACCCGAAGGTCTGAAGAAAACCCTGCG
GGATGAGATCAATGCCATTCTGCAGAAGAGGATTATGGTGCTGGATGGAGGGATGGGGACCATGATCCAGCGGGAGAAGCTAAACGAAGA
ACACTTCCGAGGTCAGGAATTTAAAGATCATGCCAGGCCGCTGAAAGGCAACAATGACATTTTAAGTATAACTCAGCCTGATGTCATTTA
CCAAATCCATAAGGAATACTTGCTGGCTGGGGCAGATATCATTGAAACAAATACTTTTAGCAGCACTAGTATTGCCCAAGCTGACTATGG
CCTTGAACACTTGGCCTACCGGATGAACATGTGCTCTGCAGGAGTGGCCAGAAAAGCTGCCGAGGAGGTAACTCTCCAGACAGGAATTAA
GAGGTTTGTGGCAGGGGCTCTGGGTCCGACTAATAAGACACTCTCTGTGTCCCCATCTGTGGAAAGGCCGGATTATAGGAACATCACATT
TGATGAGCTTGTTGAAGCATACCAAGAGCAGGCCAAAGGACTTCTGGATGGCGGGGTTGATATCTTACTCATTGAAACTATTTTTGATAC
TGCCAATGCCAAGGCAGCCTTGTTTGCACTCCAAAATCTTTTTGAGGAGAAATATGCTCCCCGGCCTATCTTTATTTCAGGGACGATCGT
TGATAAAAGTGGGCGGACTCTTTCCGGACAGACAGGAGAGGGATTTGTCATCAGCGTGTCTCATGGAGAACCACTCTGCATTGGATTAAA
TTGTGCTTTGGGTGCAGCTGAAATGAGACCTTTTATTGAAATAATTGGAAAATGTACAACAGCCTATGTCCTCTGTTATCCCAATGCAGG
TCTTCCCAACACCTTTGGTGACTATGATGAAACGCCTTCTATGATGGCCAAGCACCTAAAGGATTTTGCTATGGATGGCTTGGTCAATAT
AGTTGGAGGATGCTGTGGGTCAACACCAGATCATATCAGGGAAATTGCTGAAGCTGTGAAAAATTGTAAGCCTAGAGTTCCACCTGCCAC
TGCTTTTGAAGGACATATGTTACTGTCTGGTCTAGAGCCCTTCAGGATTGGACCGTACACCAACTTTGTTAACATTGGAGAGCGCTGTAA
TGTTGCAGGATCAAGGAAGTTTGCTAAACTCATCATGGCAGGAAACTATGAAGAAGCCTTGTGTGTTGCCAAAGTGCAGGTGGAAATGGG
AGCCCAGGTGTTGGATGTCAACATGGATGATGGCATGCTAGATGGTCCAAGTGCAATGACCAGATTTTGCAACTTAATTGCTTCCGAGCC
AGACATCGCAAAGGTACCTTTGTGCATCGACTCCTCCAATTTTGCTGTGATTGAAGCTGGGTTAAAGTGCTGCCAAGGGAAGTGCATTGT
CAATAGCATTAGTCTGAAGGAAGGAGAGGACGACTTCTTGGAGAAGGCCAGGAAGATTAAAAAGTATGGAGCTGCTATGGTGGTCATGGC
TTTTGATGAAGAAGGACAGTTGAAACCAAGACTGAAGACTGAACCTGAAGAAGTTTCCATAGAAGACAGTGCCCAGAGTGACCTCAAAGA
AGTGATGGTGCTGAACGCAACAGAATCATTTGTATATGAGCCCAAAGAGCAGAAGAAAATGTTTCATGCCACAGTGGCAACTGAGAATGA
AGTCTTCCGAGTGAAGGTTTTTAATATTGACCTAAAGGAGAAGTTCACCCCAAAGAAGATCATTGCCATAGCAAATTATGTTTGCCGCAA
TGGGTTCCTGGAGGTATATCCTTTCACACTTGTGGCTGATGTGAATGCTGACCGAAACATGGAGATCCCAAAAGGATTGATTAGAAGTGC
CAGCGTAACTCCTAAAATCAATCAGCTTTGCTCACAAACTAAAGGAAGTTTTGTGAATGGGGTGTTTGAGGTACATAAGAAAAATGTAAG
GGGTGAATTCACTTATTATGAAATACAAGATAATACAGGGAAGATGGAAGTGGTGGTGCATGGACGACTGACCACAATCAACTGTGAGGA
AGGAGATAAACTGAAACTCACCTGCTTTGAATTGGCACCGAAAAGTGGGAATACCGGGGAGTTGAGATCTGTAATTCATAGTCACATCAA
GGTCATCAAGACCAGGAAAAACAAGAAAGACATACTCAATCCTGATTCAAGTATGGAAACTTCACCAGACTTTTTCTTCTAAAATCTGGA
TGTCATTGACGATAATGTTTATGGAGATAAGGTCTAAGTGCCTAAAAAAATGTACATATACCTGGTTGAAATACAACACTATACATACAC
ACCACCATATATACTAGCTGTTAATCCTATGGAATGGGGTATTGGGAGTGCTTTTTTAATTTTTCATAGTTTTTTTTTAATAAAATGGCA

>In-frame_ENST00000366577_ENST00000430894_TCGA-A8-A07O-01A_MTR_chr1_237001899_-_IFI16_chr1_159021469_length(amino acids)=766AA_start in transcript=301_stop in transcript=2601
MALAGVALGRRHLWRARLLCRALCARRRLDNMSPALQDLSQPEGLKKTLRDEINAILQKRIMVLDGGMGTMIQREKLNEEHFRGQEFKDH
ARPLKGNNDILSITQPDVIYQIHKEYLLAGADIIETNTFSSTSIAQADYGLEHLAYRMNMCSAGVARKAAEEVTLQTGIKRFVAGALGPT
NKTLSVSPSVERPDYRNITFDELVEAYQEQAKGLLDGGVDILLIETIFDTANAKAALFALQNLFEEKYAPRPIFISGTIVDKSGRTLSGQ
TGEGFVISVSHGEPLCIGLNCALGAAEMRPFIEIIGKCTTAYVLCYPNAGLPNTFGDYDETPSMMAKHLKDFAMDGLVNIVGGCCGSTPD
HIREIAEAVKNCKPRVPPATAFEGHMLLSGLEPFRIGPYTNFVNIGERCNVAGSRKFAKLIMAGNYEEALCVAKVQVEMGAQVLDVNMDD
GMLDGPSAMTRFCNLIASEPDIAKVPLCIDSSNFAVIEAGLKCCQGKCIVNSISLKEGEDDFLEKARKIKKYGAAMVVMAFDEEGQLKPR
LKTEPEEVSIEDSAQSDLKEVMVLNATESFVYEPKEQKKMFHATVATENEVFRVKVFNIDLKEKFTPKKIIAIANYVCRNGFLEVYPFTL
VADVNADRNMEIPKGLIRSASVTPKINQLCSQTKGSFVNGVFEVHKKNVRGEFTYYEIQDNTGKMEVVVHGRLTTINCEEGDKLKLTCFE

--------------------------------------------------------------
>In-frame_ENST00000366577_ENST00000359709_TCGA-A8-A07O-01A_MTR_chr1_237001899_-_IFI16_chr1_159021469_length(transcript)=2849nt_BP=1909nt
AAAGGTTCTAAATGTCTGCGGGGCTCAGAGCCGGATGTCACGTCGTCCTCCTCTGCCGGTTTTCTCTTGGGTCCTTTTCCGTGCCGTCCC
GCGACTCCGCCTCTGGCCGCGCGTGTCTGGCTGCTAGGCCGACACCAAGGACTGGCCGGGTACCCGGGAAGAAAGCACGTGCTCCAGCAG
TTGCCGCGCCCAGCCCCGAGAGAGGCCCTAGGGCGCTGCGGGCTTTCGGGGTCCGCAGTCCCCCCGCGACGCGAGCCAACGGGAGGCGTC
AAAAGACCCGGGCCTTGTGTGGCAGGCTCGCCTGGCGCTGGCTGGCGTGGCCCTTGGCCGTCGTCACCTGTGGAGAGCACGTCTTCTCTG
CCGCGCCCTCTGCGCAAGGAGGAGACTCGACAACATGTCACCCGCGCTCCAAGACCTGTCGCAACCCGAAGGTCTGAAGAAAACCCTGCG
GGATGAGATCAATGCCATTCTGCAGAAGAGGATTATGGTGCTGGATGGAGGGATGGGGACCATGATCCAGCGGGAGAAGCTAAACGAAGA
ACACTTCCGAGGTCAGGAATTTAAAGATCATGCCAGGCCGCTGAAAGGCAACAATGACATTTTAAGTATAACTCAGCCTGATGTCATTTA
CCAAATCCATAAGGAATACTTGCTGGCTGGGGCAGATATCATTGAAACAAATACTTTTAGCAGCACTAGTATTGCCCAAGCTGACTATGG
CCTTGAACACTTGGCCTACCGGATGAACATGTGCTCTGCAGGAGTGGCCAGAAAAGCTGCCGAGGAGGTAACTCTCCAGACAGGAATTAA
GAGGTTTGTGGCAGGGGCTCTGGGTCCGACTAATAAGACACTCTCTGTGTCCCCATCTGTGGAAAGGCCGGATTATAGGAACATCACATT
TGATGAGCTTGTTGAAGCATACCAAGAGCAGGCCAAAGGACTTCTGGATGGCGGGGTTGATATCTTACTCATTGAAACTATTTTTGATAC
TGCCAATGCCAAGGCAGCCTTGTTTGCACTCCAAAATCTTTTTGAGGAGAAATATGCTCCCCGGCCTATCTTTATTTCAGGGACGATCGT
TGATAAAAGTGGGCGGACTCTTTCCGGACAGACAGGAGAGGGATTTGTCATCAGCGTGTCTCATGGAGAACCACTCTGCATTGGATTAAA
TTGTGCTTTGGGTGCAGCTGAAATGAGACCTTTTATTGAAATAATTGGAAAATGTACAACAGCCTATGTCCTCTGTTATCCCAATGCAGG
TCTTCCCAACACCTTTGGTGACTATGATGAAACGCCTTCTATGATGGCCAAGCACCTAAAGGATTTTGCTATGGATGGCTTGGTCAATAT
AGTTGGAGGATGCTGTGGGTCAACACCAGATCATATCAGGGAAATTGCTGAAGCTGTGAAAAATTGTAAGCCTAGAGTTCCACCTGCCAC
TGCTTTTGAAGGACATATGTTACTGTCTGGTCTAGAGCCCTTCAGGATTGGACCGTACACCAACTTTGTTAACATTGGAGAGCGCTGTAA
TGTTGCAGGATCAAGGAAGTTTGCTAAACTCATCATGGCAGGAAACTATGAAGAAGCCTTGTGTGTTGCCAAAGTGCAGGTGGAAATGGG
AGCCCAGGTGTTGGATGTCAACATGGATGATGGCATGCTAGATGGTCCAAGTGCAATGACCAGATTTTGCAACTTAATTGCTTCCGAGCC
AGACATCGCAAAGGTACCTTTGTGCATCGACTCCTCCAATTTTGCTGTGATTGAAGCTGGGTTAAAGTGCTGCCAAGGGAAGTGCATTGT
CAATAGCATTAGTCTGAAGGAAGGAGAGGACGACTTCTTGGAGAAGGCCAGGAAGATTAAAAAGTATGGAGCTGCTATGGTGGTCATGGC
TTTTGATGAAGAAGGACAGTTGAAACCAAGACTGAAGACTGAACCTGAAGAAGTTTCCATAGAAGACAGTGCCCAGAGTGACCTCAAAGA
AGTGATGGTGCTGAACGCAACAGAATCATTTGTATATGAGCCCAAAGAGCAGAAGAAAATGTTTCATGCCACAGTGGCAACTGAGAATGA
AGTCTTCCGAGTGAAGGTTTTTAATATTGACCTAAAGGAGAAGTTCACCCCAAAGAAGATCATTGCCATAGCAAATTATGTTTGCCGCAA
TGGGTTCCTGGAGGTATATCCTTTCACACTTGTGGCTGATGTGAATGCTGACCGAAACATGGAGATCCCAAAAGGATTGATTAGAAGTGC
CAGCGTAACTCCTAAAATCAATCAGCTTTGCTCACAAACTAAAGGAAGTTTTGTGAATGGGGTGTTTGAGGTACATAAGAAAAATGTAAG
GGGTGAATTCACTTATTATGAAATACAAGATAATACAGGGAAGATGGAAGTGGTGGTGCATGGACGACTGACCACAATCAACTGTGAGGA
AGGAGATAAACTGAAACTCACCTGCTTTGAATTGGCACCGAAAAGTGGGAATACCGGGGAGTTGAGATCTGTAATTCATAGTCACATCAA
GGTCATCAAGACCAGGAAAAACAAGAAAGACATACTCAATCCTGATTCAAGTATGGAAACTTCACCAGACTTTTTCTTCTAAAATCTGGA
TGTCATTGACGATAATGTTTATGGAGATAAGGTCTAAGTGCCTAAAAAAATGTACATATACCTGGTTGAAATACAACACTATACATACAC
ACCACCATATATACTAGCTGTTAATCCTATGGAATGGGGTATTGGGAGTGCTTTTTTAATTTTTCATAGTTTTTTTTTAATAAAATGGCA

>In-frame_ENST00000366577_ENST00000359709_TCGA-A8-A07O-01A_MTR_chr1_237001899_-_IFI16_chr1_159021469_length(amino acids)=766AA_start in transcript=301_stop in transcript=2601
MALAGVALGRRHLWRARLLCRALCARRRLDNMSPALQDLSQPEGLKKTLRDEINAILQKRIMVLDGGMGTMIQREKLNEEHFRGQEFKDH
ARPLKGNNDILSITQPDVIYQIHKEYLLAGADIIETNTFSSTSIAQADYGLEHLAYRMNMCSAGVARKAAEEVTLQTGIKRFVAGALGPT
NKTLSVSPSVERPDYRNITFDELVEAYQEQAKGLLDGGVDILLIETIFDTANAKAALFALQNLFEEKYAPRPIFISGTIVDKSGRTLSGQ
TGEGFVISVSHGEPLCIGLNCALGAAEMRPFIEIIGKCTTAYVLCYPNAGLPNTFGDYDETPSMMAKHLKDFAMDGLVNIVGGCCGSTPD
HIREIAEAVKNCKPRVPPATAFEGHMLLSGLEPFRIGPYTNFVNIGERCNVAGSRKFAKLIMAGNYEEALCVAKVQVEMGAQVLDVNMDD
GMLDGPSAMTRFCNLIASEPDIAKVPLCIDSSNFAVIEAGLKCCQGKCIVNSISLKEGEDDFLEKARKIKKYGAAMVVMAFDEEGQLKPR
LKTEPEEVSIEDSAQSDLKEVMVLNATESFVYEPKEQKKMFHATVATENEVFRVKVFNIDLKEKFTPKKIIAIANYVCRNGFLEVYPFTL
VADVNADRNMEIPKGLIRSASVTPKINQLCSQTKGSFVNGVFEVHKKNVRGEFTYYEIQDNTGKMEVVVHGRLTTINCEEGDKLKLTCFE

--------------------------------------------------------------
>In-frame_ENST00000366577_ENST00000448393_TCGA-A8-A07O-01A_MTR_chr1_237001899_-_IFI16_chr1_159021469_length(transcript)=2825nt_BP=1909nt
AAAGGTTCTAAATGTCTGCGGGGCTCAGAGCCGGATGTCACGTCGTCCTCCTCTGCCGGTTTTCTCTTGGGTCCTTTTCCGTGCCGTCCC
GCGACTCCGCCTCTGGCCGCGCGTGTCTGGCTGCTAGGCCGACACCAAGGACTGGCCGGGTACCCGGGAAGAAAGCACGTGCTCCAGCAG
TTGCCGCGCCCAGCCCCGAGAGAGGCCCTAGGGCGCTGCGGGCTTTCGGGGTCCGCAGTCCCCCCGCGACGCGAGCCAACGGGAGGCGTC
AAAAGACCCGGGCCTTGTGTGGCAGGCTCGCCTGGCGCTGGCTGGCGTGGCCCTTGGCCGTCGTCACCTGTGGAGAGCACGTCTTCTCTG
CCGCGCCCTCTGCGCAAGGAGGAGACTCGACAACATGTCACCCGCGCTCCAAGACCTGTCGCAACCCGAAGGTCTGAAGAAAACCCTGCG
GGATGAGATCAATGCCATTCTGCAGAAGAGGATTATGGTGCTGGATGGAGGGATGGGGACCATGATCCAGCGGGAGAAGCTAAACGAAGA
ACACTTCCGAGGTCAGGAATTTAAAGATCATGCCAGGCCGCTGAAAGGCAACAATGACATTTTAAGTATAACTCAGCCTGATGTCATTTA
CCAAATCCATAAGGAATACTTGCTGGCTGGGGCAGATATCATTGAAACAAATACTTTTAGCAGCACTAGTATTGCCCAAGCTGACTATGG
CCTTGAACACTTGGCCTACCGGATGAACATGTGCTCTGCAGGAGTGGCCAGAAAAGCTGCCGAGGAGGTAACTCTCCAGACAGGAATTAA
GAGGTTTGTGGCAGGGGCTCTGGGTCCGACTAATAAGACACTCTCTGTGTCCCCATCTGTGGAAAGGCCGGATTATAGGAACATCACATT
TGATGAGCTTGTTGAAGCATACCAAGAGCAGGCCAAAGGACTTCTGGATGGCGGGGTTGATATCTTACTCATTGAAACTATTTTTGATAC
TGCCAATGCCAAGGCAGCCTTGTTTGCACTCCAAAATCTTTTTGAGGAGAAATATGCTCCCCGGCCTATCTTTATTTCAGGGACGATCGT
TGATAAAAGTGGGCGGACTCTTTCCGGACAGACAGGAGAGGGATTTGTCATCAGCGTGTCTCATGGAGAACCACTCTGCATTGGATTAAA
TTGTGCTTTGGGTGCAGCTGAAATGAGACCTTTTATTGAAATAATTGGAAAATGTACAACAGCCTATGTCCTCTGTTATCCCAATGCAGG
TCTTCCCAACACCTTTGGTGACTATGATGAAACGCCTTCTATGATGGCCAAGCACCTAAAGGATTTTGCTATGGATGGCTTGGTCAATAT
AGTTGGAGGATGCTGTGGGTCAACACCAGATCATATCAGGGAAATTGCTGAAGCTGTGAAAAATTGTAAGCCTAGAGTTCCACCTGCCAC
TGCTTTTGAAGGACATATGTTACTGTCTGGTCTAGAGCCCTTCAGGATTGGACCGTACACCAACTTTGTTAACATTGGAGAGCGCTGTAA
TGTTGCAGGATCAAGGAAGTTTGCTAAACTCATCATGGCAGGAAACTATGAAGAAGCCTTGTGTGTTGCCAAAGTGCAGGTGGAAATGGG
AGCCCAGGTGTTGGATGTCAACATGGATGATGGCATGCTAGATGGTCCAAGTGCAATGACCAGATTTTGCAACTTAATTGCTTCCGAGCC
AGACATCGCAAAGGTACCTTTGTGCATCGACTCCTCCAATTTTGCTGTGATTGAAGCTGGGTTAAAGTGCTGCCAAGGGAAGTGCATTGT
CAATAGCATTAGTCTGAAGGAAGGAGAGGACGACTTCTTGGAGAAGGCCAGGAAGATTAAAAAGTATGGAGCTGCTATGGTGGTCATGGC
TTTTGATGAAGAAGGACAGTTGAAACCAAGACTGAAGACTGAACCTGAAGAAGTTTCCATAGAAGACAGTGCCCAGAGTGACCTCAAAGA
AGTGATGGTGCTGAACGCAACAGAATCATTTGTATATGAGCCCAAAGAGCAGAAGAAAATGTTTCATGCCACAGTGGCAACTGAGAATGA
AGTCTTCCGAGTGAAGGTTTTTAATATTGACCTAAAGGAGAAGTTCACCCCAAAGAAGATCATTGCCATAGCAAATTATGTTTGCCGCAA
TGGGTTCCTGGAGGTATATCCTTTCACACTTGTGGCTGATGTGAATGCTGACCGAAACATGGAGATCCCAAAAGGATTGATTAGAAGTGC
CAGCGTAACTCCTAAAATCAATCAGCTTTGCTCACAAACTAAAGGAAGTTTTGTGAATGGGGTGTTTGAGGTACATAAGAAAAATGTAAG
GGGTGAATTCACTTATTATGAAATACAAGATAATACAGGGAAGATGGAAGTGGTGGTGCATGGACGACTGACCACAATCAACTGTGAGGA
AGGAGATAAACTGAAACTCACCTGCTTTGAATTGGCACCGAAAAGTGGGAATACCGGGGAGTTGAGATCTGTAATTCATAGTCACATCAA
GGTCATCAAGACCAGGAAAAACAAGAAAGACATACTCAATCCTGATTCAAGTATGGAAACTTCACCAGACTTTTTCTTCTAAAATCTGGA
TGTCATTGACGATAATGTTTATGGAGATAAGGTCTAAGTGCCTAAAAAAATGTACATATACCTGGTTGAAATACAACACTATACATACAC
ACCACCATATATACTAGCTGTTAATCCTATGGAATGGGGTATTGGGAGTGCTTTTTTAATTTTTCATAGTTTTTTTTTAATAAAATGGCA

>In-frame_ENST00000366577_ENST00000448393_TCGA-A8-A07O-01A_MTR_chr1_237001899_-_IFI16_chr1_159021469_length(amino acids)=766AA_start in transcript=301_stop in transcript=2601
MALAGVALGRRHLWRARLLCRALCARRRLDNMSPALQDLSQPEGLKKTLRDEINAILQKRIMVLDGGMGTMIQREKLNEEHFRGQEFKDH
ARPLKGNNDILSITQPDVIYQIHKEYLLAGADIIETNTFSSTSIAQADYGLEHLAYRMNMCSAGVARKAAEEVTLQTGIKRFVAGALGPT
NKTLSVSPSVERPDYRNITFDELVEAYQEQAKGLLDGGVDILLIETIFDTANAKAALFALQNLFEEKYAPRPIFISGTIVDKSGRTLSGQ
TGEGFVISVSHGEPLCIGLNCALGAAEMRPFIEIIGKCTTAYVLCYPNAGLPNTFGDYDETPSMMAKHLKDFAMDGLVNIVGGCCGSTPD
HIREIAEAVKNCKPRVPPATAFEGHMLLSGLEPFRIGPYTNFVNIGERCNVAGSRKFAKLIMAGNYEEALCVAKVQVEMGAQVLDVNMDD
GMLDGPSAMTRFCNLIASEPDIAKVPLCIDSSNFAVIEAGLKCCQGKCIVNSISLKEGEDDFLEKARKIKKYGAAMVVMAFDEEGQLKPR
LKTEPEEVSIEDSAQSDLKEVMVLNATESFVYEPKEQKKMFHATVATENEVFRVKVFNIDLKEKFTPKKIIAIANYVCRNGFLEVYPFTL
VADVNADRNMEIPKGLIRSASVTPKINQLCSQTKGSFVNGVFEVHKKNVRGEFTYYEIQDNTGKMEVVVHGRLTTINCEEGDKLKLTCFE

--------------------------------------------------------------
>In-frame_ENST00000535889_ENST00000340979_TCGA-A8-A07O-01A_MTR_chr1_237001899_-_IFI16_chr1_159021469_length(transcript)=2482nt_BP=1537nt
CGCAAGGAGGAGACTCGACAACATGTCACCCGCGCTCCAAGACCTGTCGCAACCCGAAGGTCTGAAGAAAACCCTGCGGGATGAGATCAA
TGCCATTCTGCAGAAGAGGATTATGGTGCTGGATGGAGGGATGGGGACCATGATCCAGCGGGAGAAGCTAAACGAAGAACACTTCCGAGG
TCAGGAATTTAAAGATCATGCCAGGCCGCTGAAAGGCAACAATGACATTTTAAGTATAACTCAGCCTGATGTCATTTACCAAATCCATAA
GGAATACTTGCTGGCTGGGGCAGATATCATTGAAACAAATACTTTTAGCAGCACTAGTATTGCCCAAGCTGACTATGGCCTTGAACACTT
GGCCTACCGGATGAACATGTGCTCTGCAGGAGTGGCCAGAAAAGCTGCCGAGGAGGTAACTCTCCAGACAGGAATTAAGAGGTTTGTGGC
AGGGGCTCTGGGTCCGACTAATAAGACACTCTCTGTGTCCCCATCTGTGGAAAGGCCGGATTATAGGAACATCACATTTGATGAGCTTGT
TGAAGCATACCAAGAGCAGGCCAAAGGACTTCTGGATGGCGGGGTTGATATCTTACTCATTGAAACTATTTTTGATACTGCCAATGCCAA
GGCAGCCTTGTTTGCACTCCAAAATCTTTTTGAGGAGAAATATGCTCCCCGGCCTATCTTTATTTCAGGGACGATCGTTGATAAAAGTGG
GCGGACTCTTTCCGGACAGACAGGAGAGGGATTTGTCATCAGCGTGTCTCATGGAGAACCACTCTGCATTGGATTAAATTGTGCTTTGGG
TGCAGCTGAAATGAGACCTTTTATTGAAATAATTGGAAAATGTACAACAGCCTATGTCCTCTGTTATCCCAATGCAGGTCTTCCCAACAC
CTTTGGTGACTATGATGAAACGCCTTCTATGATGGCCAAGCACCTAAAGGATTTTGCTATGGATGGCTTGGTCAATATAGTTGGAGGATG
CTGTGGGTCAACACCAGATCATATCAGGGAAATTGCTGAAGCTGTGAAAAATTGTAAGCCTAGAGTTCCACCTGCCACTGCTTTTGAAGG
ACATATGTTACTGTCTGGTCTAGAGCCCTTCAGGATTGGACCGTACACCAACTTTGTTAACATTGGAGAGCGCTGTAATGTTGCAGGATC
AAGGAAGTTTGCTAAACTCATCATGGCAGGAAACTATGAAGAAGCCTTGTGTGTTGCCAAAGTGCAGGTGGAAATGGGAGCCCAGGTGTT
GGATGTCAACATGGATGATGGCATGCTAGATGGTCCAAGTGCAATGACCAGATTTTGCAACTTAATTGCTTCCGAGCCAGACATCGCAAA
GGTACCTTTGTGCATCGACTCCTCCAATTTTGCTGTGATTGAAGCTGGGTTAAAGTGCTGCCAAGGGAAGTGCATTGTCAATAGCATTAG
TCTGAAGGAAGGAGAGGACGACTTCTTGGAGAAGGCCAGGAAGATTAAAAAGTATGGAGCTGCTATGGTGGTCATGGCTTTTGATGAAGA
AGGACAGTTGAAACCAAGACTGAAGACTGAACCTGAAGAAGTTTCCATAGAAGACAGTGCCCAGAGTGACCTCAAAGAAGTGATGGTGCT
GAACGCAACAGAATCATTTGTATATGAGCCCAAAGAGCAGAAGAAAATGTTTCATGCCACAGTGGCAACTGAGAATGAAGTCTTCCGAGT
GAAGGTTTTTAATATTGACCTAAAGGAGAAGTTCACCCCAAAGAAGATCATTGCCATAGCAAATTATGTTTGCCGCAATGGGTTCCTGGA
GGTATATCCTTTCACACTTGTGGCTGATGTGAATGCTGACCGAAACATGGAGATCCCAAAAGGATTGATTAGAAGTGCCAGCGTAACTCC
TAAAATCAATCAGCTTTGCTCACAAACTAAAGGAAGTTTTGTGAATGGGGTGTTTGAGGTACATAAGAAAAATGTAAGGGGTGAATTCAC
TTATTATGAAATACAAGATAATACAGGGAAGATGGAAGTGGTGGTGCATGGACGACTGACCACAATCAACTGTGAGGAAGGAGATAAACT
GAAACTCACCTGCTTTGAATTGGCACCGAAAAGTGGGAATACCGGGGAGTTGAGATCTGTAATTCATAGTCACATCAAGGTCATCAAGAC
CAGGAAAAACAAGAAAGACATACTCAATCCTGATTCAAGTATGGAAACTTCACCAGACTTTTTCTTCTAAAATCTGGATGTCATTGACGA
TAATGTTTATGGAGATAAGGTCTAAGTGCCTAAAAAAATGTACATATACCTGGTTGAAATACAACACTATACATACACACCACCATATAT
ACTAGCTGTTAATCCTATGGAATGGGGTATTGGGAGTGCTTTTTTAATTTTTCATAGTTTTTTTTTAATAAAATGGCATATTTTGCATCT

>In-frame_ENST00000535889_ENST00000340979_TCGA-A8-A07O-01A_MTR_chr1_237001899_-_IFI16_chr1_159021469_length(amino acids)=735AA_start in transcript=22_stop in transcript=2229
MSPALQDLSQPEGLKKTLRDEINAILQKRIMVLDGGMGTMIQREKLNEEHFRGQEFKDHARPLKGNNDILSITQPDVIYQIHKEYLLAGA
DIIETNTFSSTSIAQADYGLEHLAYRMNMCSAGVARKAAEEVTLQTGIKRFVAGALGPTNKTLSVSPSVERPDYRNITFDELVEAYQEQA
KGLLDGGVDILLIETIFDTANAKAALFALQNLFEEKYAPRPIFISGTIVDKSGRTLSGQTGEGFVISVSHGEPLCIGLNCALGAAEMRPF
IEIIGKCTTAYVLCYPNAGLPNTFGDYDETPSMMAKHLKDFAMDGLVNIVGGCCGSTPDHIREIAEAVKNCKPRVPPATAFEGHMLLSGL
EPFRIGPYTNFVNIGERCNVAGSRKFAKLIMAGNYEEALCVAKVQVEMGAQVLDVNMDDGMLDGPSAMTRFCNLIASEPDIAKVPLCIDS
SNFAVIEAGLKCCQGKCIVNSISLKEGEDDFLEKARKIKKYGAAMVVMAFDEEGQLKPRLKTEPEEVSIEDSAQSDLKEVMVLNATESFV
YEPKEQKKMFHATVATENEVFRVKVFNIDLKEKFTPKKIIAIANYVCRNGFLEVYPFTLVADVNADRNMEIPKGLIRSASVTPKINQLCS
QTKGSFVNGVFEVHKKNVRGEFTYYEIQDNTGKMEVVVHGRLTTINCEEGDKLKLTCFELAPKSGNTGELRSVIHSHIKVIKTRKNKKDI

--------------------------------------------------------------
>In-frame_ENST00000535889_ENST00000368131_TCGA-A8-A07O-01A_MTR_chr1_237001899_-_IFI16_chr1_159021469_length(transcript)=2484nt_BP=1537nt
CGCAAGGAGGAGACTCGACAACATGTCACCCGCGCTCCAAGACCTGTCGCAACCCGAAGGTCTGAAGAAAACCCTGCGGGATGAGATCAA
TGCCATTCTGCAGAAGAGGATTATGGTGCTGGATGGAGGGATGGGGACCATGATCCAGCGGGAGAAGCTAAACGAAGAACACTTCCGAGG
TCAGGAATTTAAAGATCATGCCAGGCCGCTGAAAGGCAACAATGACATTTTAAGTATAACTCAGCCTGATGTCATTTACCAAATCCATAA
GGAATACTTGCTGGCTGGGGCAGATATCATTGAAACAAATACTTTTAGCAGCACTAGTATTGCCCAAGCTGACTATGGCCTTGAACACTT
GGCCTACCGGATGAACATGTGCTCTGCAGGAGTGGCCAGAAAAGCTGCCGAGGAGGTAACTCTCCAGACAGGAATTAAGAGGTTTGTGGC
AGGGGCTCTGGGTCCGACTAATAAGACACTCTCTGTGTCCCCATCTGTGGAAAGGCCGGATTATAGGAACATCACATTTGATGAGCTTGT
TGAAGCATACCAAGAGCAGGCCAAAGGACTTCTGGATGGCGGGGTTGATATCTTACTCATTGAAACTATTTTTGATACTGCCAATGCCAA
GGCAGCCTTGTTTGCACTCCAAAATCTTTTTGAGGAGAAATATGCTCCCCGGCCTATCTTTATTTCAGGGACGATCGTTGATAAAAGTGG
GCGGACTCTTTCCGGACAGACAGGAGAGGGATTTGTCATCAGCGTGTCTCATGGAGAACCACTCTGCATTGGATTAAATTGTGCTTTGGG
TGCAGCTGAAATGAGACCTTTTATTGAAATAATTGGAAAATGTACAACAGCCTATGTCCTCTGTTATCCCAATGCAGGTCTTCCCAACAC
CTTTGGTGACTATGATGAAACGCCTTCTATGATGGCCAAGCACCTAAAGGATTTTGCTATGGATGGCTTGGTCAATATAGTTGGAGGATG
CTGTGGGTCAACACCAGATCATATCAGGGAAATTGCTGAAGCTGTGAAAAATTGTAAGCCTAGAGTTCCACCTGCCACTGCTTTTGAAGG
ACATATGTTACTGTCTGGTCTAGAGCCCTTCAGGATTGGACCGTACACCAACTTTGTTAACATTGGAGAGCGCTGTAATGTTGCAGGATC
AAGGAAGTTTGCTAAACTCATCATGGCAGGAAACTATGAAGAAGCCTTGTGTGTTGCCAAAGTGCAGGTGGAAATGGGAGCCCAGGTGTT
GGATGTCAACATGGATGATGGCATGCTAGATGGTCCAAGTGCAATGACCAGATTTTGCAACTTAATTGCTTCCGAGCCAGACATCGCAAA
GGTACCTTTGTGCATCGACTCCTCCAATTTTGCTGTGATTGAAGCTGGGTTAAAGTGCTGCCAAGGGAAGTGCATTGTCAATAGCATTAG
TCTGAAGGAAGGAGAGGACGACTTCTTGGAGAAGGCCAGGAAGATTAAAAAGTATGGAGCTGCTATGGTGGTCATGGCTTTTGATGAAGA
AGGACAGTTGAAACCAAGACTGAAGACTGAACCTGAAGAAGTTTCCATAGAAGACAGTGCCCAGAGTGACCTCAAAGAAGTGATGGTGCT
GAACGCAACAGAATCATTTGTATATGAGCCCAAAGAGCAGAAGAAAATGTTTCATGCCACAGTGGCAACTGAGAATGAAGTCTTCCGAGT
GAAGGTTTTTAATATTGACCTAAAGGAGAAGTTCACCCCAAAGAAGATCATTGCCATAGCAAATTATGTTTGCCGCAATGGGTTCCTGGA
GGTATATCCTTTCACACTTGTGGCTGATGTGAATGCTGACCGAAACATGGAGATCCCAAAAGGATTGATTAGAAGTGCCAGCGTAACTCC
TAAAATCAATCAGCTTTGCTCACAAACTAAAGGAAGTTTTGTGAATGGGGTGTTTGAGGTACATAAGAAAAATGTAAGGGGTGAATTCAC
TTATTATGAAATACAAGATAATACAGGGAAGATGGAAGTGGTGGTGCATGGACGACTGACCACAATCAACTGTGAGGAAGGAGATAAACT
GAAACTCACCTGCTTTGAATTGGCACCGAAAAGTGGGAATACCGGGGAGTTGAGATCTGTAATTCATAGTCACATCAAGGTCATCAAGAC
CAGGAAAAACAAGAAAGACATACTCAATCCTGATTCAAGTATGGAAACTTCACCAGACTTTTTCTTCTAAAATCTGGATGTCATTGACGA
TAATGTTTATGGAGATAAGGTCTAAGTGCCTAAAAAAATGTACATATACCTGGTTGAAATACAACACTATACATACACACCACCATATAT
ACTAGCTGTTAATCCTATGGAATGGGGTATTGGGAGTGCTTTTTTAATTTTTCATAGTTTTTTTTTAATAAAATGGCATATTTTGCATCT

>In-frame_ENST00000535889_ENST00000368131_TCGA-A8-A07O-01A_MTR_chr1_237001899_-_IFI16_chr1_159021469_length(amino acids)=735AA_start in transcript=22_stop in transcript=2229
MSPALQDLSQPEGLKKTLRDEINAILQKRIMVLDGGMGTMIQREKLNEEHFRGQEFKDHARPLKGNNDILSITQPDVIYQIHKEYLLAGA
DIIETNTFSSTSIAQADYGLEHLAYRMNMCSAGVARKAAEEVTLQTGIKRFVAGALGPTNKTLSVSPSVERPDYRNITFDELVEAYQEQA
KGLLDGGVDILLIETIFDTANAKAALFALQNLFEEKYAPRPIFISGTIVDKSGRTLSGQTGEGFVISVSHGEPLCIGLNCALGAAEMRPF
IEIIGKCTTAYVLCYPNAGLPNTFGDYDETPSMMAKHLKDFAMDGLVNIVGGCCGSTPDHIREIAEAVKNCKPRVPPATAFEGHMLLSGL
EPFRIGPYTNFVNIGERCNVAGSRKFAKLIMAGNYEEALCVAKVQVEMGAQVLDVNMDDGMLDGPSAMTRFCNLIASEPDIAKVPLCIDS
SNFAVIEAGLKCCQGKCIVNSISLKEGEDDFLEKARKIKKYGAAMVVMAFDEEGQLKPRLKTEPEEVSIEDSAQSDLKEVMVLNATESFV
YEPKEQKKMFHATVATENEVFRVKVFNIDLKEKFTPKKIIAIANYVCRNGFLEVYPFTLVADVNADRNMEIPKGLIRSASVTPKINQLCS
QTKGSFVNGVFEVHKKNVRGEFTYYEIQDNTGKMEVVVHGRLTTINCEEGDKLKLTCFELAPKSGNTGELRSVIHSHIKVIKTRKNKKDI

--------------------------------------------------------------
>In-frame_ENST00000535889_ENST00000368132_TCGA-A8-A07O-01A_MTR_chr1_237001899_-_IFI16_chr1_159021469_length(transcript)=2480nt_BP=1537nt
CGCAAGGAGGAGACTCGACAACATGTCACCCGCGCTCCAAGACCTGTCGCAACCCGAAGGTCTGAAGAAAACCCTGCGGGATGAGATCAA
TGCCATTCTGCAGAAGAGGATTATGGTGCTGGATGGAGGGATGGGGACCATGATCCAGCGGGAGAAGCTAAACGAAGAACACTTCCGAGG
TCAGGAATTTAAAGATCATGCCAGGCCGCTGAAAGGCAACAATGACATTTTAAGTATAACTCAGCCTGATGTCATTTACCAAATCCATAA
GGAATACTTGCTGGCTGGGGCAGATATCATTGAAACAAATACTTTTAGCAGCACTAGTATTGCCCAAGCTGACTATGGCCTTGAACACTT
GGCCTACCGGATGAACATGTGCTCTGCAGGAGTGGCCAGAAAAGCTGCCGAGGAGGTAACTCTCCAGACAGGAATTAAGAGGTTTGTGGC
AGGGGCTCTGGGTCCGACTAATAAGACACTCTCTGTGTCCCCATCTGTGGAAAGGCCGGATTATAGGAACATCACATTTGATGAGCTTGT
TGAAGCATACCAAGAGCAGGCCAAAGGACTTCTGGATGGCGGGGTTGATATCTTACTCATTGAAACTATTTTTGATACTGCCAATGCCAA
GGCAGCCTTGTTTGCACTCCAAAATCTTTTTGAGGAGAAATATGCTCCCCGGCCTATCTTTATTTCAGGGACGATCGTTGATAAAAGTGG
GCGGACTCTTTCCGGACAGACAGGAGAGGGATTTGTCATCAGCGTGTCTCATGGAGAACCACTCTGCATTGGATTAAATTGTGCTTTGGG
TGCAGCTGAAATGAGACCTTTTATTGAAATAATTGGAAAATGTACAACAGCCTATGTCCTCTGTTATCCCAATGCAGGTCTTCCCAACAC
CTTTGGTGACTATGATGAAACGCCTTCTATGATGGCCAAGCACCTAAAGGATTTTGCTATGGATGGCTTGGTCAATATAGTTGGAGGATG
CTGTGGGTCAACACCAGATCATATCAGGGAAATTGCTGAAGCTGTGAAAAATTGTAAGCCTAGAGTTCCACCTGCCACTGCTTTTGAAGG
ACATATGTTACTGTCTGGTCTAGAGCCCTTCAGGATTGGACCGTACACCAACTTTGTTAACATTGGAGAGCGCTGTAATGTTGCAGGATC
AAGGAAGTTTGCTAAACTCATCATGGCAGGAAACTATGAAGAAGCCTTGTGTGTTGCCAAAGTGCAGGTGGAAATGGGAGCCCAGGTGTT
GGATGTCAACATGGATGATGGCATGCTAGATGGTCCAAGTGCAATGACCAGATTTTGCAACTTAATTGCTTCCGAGCCAGACATCGCAAA
GGTACCTTTGTGCATCGACTCCTCCAATTTTGCTGTGATTGAAGCTGGGTTAAAGTGCTGCCAAGGGAAGTGCATTGTCAATAGCATTAG
TCTGAAGGAAGGAGAGGACGACTTCTTGGAGAAGGCCAGGAAGATTAAAAAGTATGGAGCTGCTATGGTGGTCATGGCTTTTGATGAAGA
AGGACAGTTGAAACCAAGACTGAAGACTGAACCTGAAGAAGTTTCCATAGAAGACAGTGCCCAGAGTGACCTCAAAGAAGTGATGGTGCT
GAACGCAACAGAATCATTTGTATATGAGCCCAAAGAGCAGAAGAAAATGTTTCATGCCACAGTGGCAACTGAGAATGAAGTCTTCCGAGT
GAAGGTTTTTAATATTGACCTAAAGGAGAAGTTCACCCCAAAGAAGATCATTGCCATAGCAAATTATGTTTGCCGCAATGGGTTCCTGGA
GGTATATCCTTTCACACTTGTGGCTGATGTGAATGCTGACCGAAACATGGAGATCCCAAAAGGATTGATTAGAAGTGCCAGCGTAACTCC
TAAAATCAATCAGCTTTGCTCACAAACTAAAGGAAGTTTTGTGAATGGGGTGTTTGAGGTACATAAGAAAAATGTAAGGGGTGAATTCAC
TTATTATGAAATACAAGATAATACAGGGAAGATGGAAGTGGTGGTGCATGGACGACTGACCACAATCAACTGTGAGGAAGGAGATAAACT
GAAACTCACCTGCTTTGAATTGGCACCGAAAAGTGGGAATACCGGGGAGTTGAGATCTGTAATTCATAGTCACATCAAGGTCATCAAGAC
CAGGAAAAACAAGAAAGACATACTCAATCCTGATTCAAGTATGGAAACTTCACCAGACTTTTTCTTCTAAAATCTGGATGTCATTGACGA
TAATGTTTATGGAGATAAGGTCTAAGTGCCTAAAAAAATGTACATATACCTGGTTGAAATACAACACTATACATACACACCACCATATAT
ACTAGCTGTTAATCCTATGGAATGGGGTATTGGGAGTGCTTTTTTAATTTTTCATAGTTTTTTTTTAATAAAATGGCATATTTTGCATCT

>In-frame_ENST00000535889_ENST00000368132_TCGA-A8-A07O-01A_MTR_chr1_237001899_-_IFI16_chr1_159021469_length(amino acids)=735AA_start in transcript=22_stop in transcript=2229
MSPALQDLSQPEGLKKTLRDEINAILQKRIMVLDGGMGTMIQREKLNEEHFRGQEFKDHARPLKGNNDILSITQPDVIYQIHKEYLLAGA
DIIETNTFSSTSIAQADYGLEHLAYRMNMCSAGVARKAAEEVTLQTGIKRFVAGALGPTNKTLSVSPSVERPDYRNITFDELVEAYQEQA
KGLLDGGVDILLIETIFDTANAKAALFALQNLFEEKYAPRPIFISGTIVDKSGRTLSGQTGEGFVISVSHGEPLCIGLNCALGAAEMRPF
IEIIGKCTTAYVLCYPNAGLPNTFGDYDETPSMMAKHLKDFAMDGLVNIVGGCCGSTPDHIREIAEAVKNCKPRVPPATAFEGHMLLSGL
EPFRIGPYTNFVNIGERCNVAGSRKFAKLIMAGNYEEALCVAKVQVEMGAQVLDVNMDDGMLDGPSAMTRFCNLIASEPDIAKVPLCIDS
SNFAVIEAGLKCCQGKCIVNSISLKEGEDDFLEKARKIKKYGAAMVVMAFDEEGQLKPRLKTEPEEVSIEDSAQSDLKEVMVLNATESFV
YEPKEQKKMFHATVATENEVFRVKVFNIDLKEKFTPKKIIAIANYVCRNGFLEVYPFTLVADVNADRNMEIPKGLIRSASVTPKINQLCS
QTKGSFVNGVFEVHKKNVRGEFTYYEIQDNTGKMEVVVHGRLTTINCEEGDKLKLTCFELAPKSGNTGELRSVIHSHIKVIKTRKNKKDI

--------------------------------------------------------------
>In-frame_ENST00000535889_ENST00000295809_TCGA-A8-A07O-01A_MTR_chr1_237001899_-_IFI16_chr1_159021469_length(transcript)=2484nt_BP=1537nt
CGCAAGGAGGAGACTCGACAACATGTCACCCGCGCTCCAAGACCTGTCGCAACCCGAAGGTCTGAAGAAAACCCTGCGGGATGAGATCAA
TGCCATTCTGCAGAAGAGGATTATGGTGCTGGATGGAGGGATGGGGACCATGATCCAGCGGGAGAAGCTAAACGAAGAACACTTCCGAGG
TCAGGAATTTAAAGATCATGCCAGGCCGCTGAAAGGCAACAATGACATTTTAAGTATAACTCAGCCTGATGTCATTTACCAAATCCATAA
GGAATACTTGCTGGCTGGGGCAGATATCATTGAAACAAATACTTTTAGCAGCACTAGTATTGCCCAAGCTGACTATGGCCTTGAACACTT
GGCCTACCGGATGAACATGTGCTCTGCAGGAGTGGCCAGAAAAGCTGCCGAGGAGGTAACTCTCCAGACAGGAATTAAGAGGTTTGTGGC
AGGGGCTCTGGGTCCGACTAATAAGACACTCTCTGTGTCCCCATCTGTGGAAAGGCCGGATTATAGGAACATCACATTTGATGAGCTTGT
TGAAGCATACCAAGAGCAGGCCAAAGGACTTCTGGATGGCGGGGTTGATATCTTACTCATTGAAACTATTTTTGATACTGCCAATGCCAA
GGCAGCCTTGTTTGCACTCCAAAATCTTTTTGAGGAGAAATATGCTCCCCGGCCTATCTTTATTTCAGGGACGATCGTTGATAAAAGTGG
GCGGACTCTTTCCGGACAGACAGGAGAGGGATTTGTCATCAGCGTGTCTCATGGAGAACCACTCTGCATTGGATTAAATTGTGCTTTGGG
TGCAGCTGAAATGAGACCTTTTATTGAAATAATTGGAAAATGTACAACAGCCTATGTCCTCTGTTATCCCAATGCAGGTCTTCCCAACAC
CTTTGGTGACTATGATGAAACGCCTTCTATGATGGCCAAGCACCTAAAGGATTTTGCTATGGATGGCTTGGTCAATATAGTTGGAGGATG
CTGTGGGTCAACACCAGATCATATCAGGGAAATTGCTGAAGCTGTGAAAAATTGTAAGCCTAGAGTTCCACCTGCCACTGCTTTTGAAGG
ACATATGTTACTGTCTGGTCTAGAGCCCTTCAGGATTGGACCGTACACCAACTTTGTTAACATTGGAGAGCGCTGTAATGTTGCAGGATC
AAGGAAGTTTGCTAAACTCATCATGGCAGGAAACTATGAAGAAGCCTTGTGTGTTGCCAAAGTGCAGGTGGAAATGGGAGCCCAGGTGTT
GGATGTCAACATGGATGATGGCATGCTAGATGGTCCAAGTGCAATGACCAGATTTTGCAACTTAATTGCTTCCGAGCCAGACATCGCAAA
GGTACCTTTGTGCATCGACTCCTCCAATTTTGCTGTGATTGAAGCTGGGTTAAAGTGCTGCCAAGGGAAGTGCATTGTCAATAGCATTAG
TCTGAAGGAAGGAGAGGACGACTTCTTGGAGAAGGCCAGGAAGATTAAAAAGTATGGAGCTGCTATGGTGGTCATGGCTTTTGATGAAGA
AGGACAGTTGAAACCAAGACTGAAGACTGAACCTGAAGAAGTTTCCATAGAAGACAGTGCCCAGAGTGACCTCAAAGAAGTGATGGTGCT
GAACGCAACAGAATCATTTGTATATGAGCCCAAAGAGCAGAAGAAAATGTTTCATGCCACAGTGGCAACTGAGAATGAAGTCTTCCGAGT
GAAGGTTTTTAATATTGACCTAAAGGAGAAGTTCACCCCAAAGAAGATCATTGCCATAGCAAATTATGTTTGCCGCAATGGGTTCCTGGA
GGTATATCCTTTCACACTTGTGGCTGATGTGAATGCTGACCGAAACATGGAGATCCCAAAAGGATTGATTAGAAGTGCCAGCGTAACTCC
TAAAATCAATCAGCTTTGCTCACAAACTAAAGGAAGTTTTGTGAATGGGGTGTTTGAGGTACATAAGAAAAATGTAAGGGGTGAATTCAC
TTATTATGAAATACAAGATAATACAGGGAAGATGGAAGTGGTGGTGCATGGACGACTGACCACAATCAACTGTGAGGAAGGAGATAAACT
GAAACTCACCTGCTTTGAATTGGCACCGAAAAGTGGGAATACCGGGGAGTTGAGATCTGTAATTCATAGTCACATCAAGGTCATCAAGAC
CAGGAAAAACAAGAAAGACATACTCAATCCTGATTCAAGTATGGAAACTTCACCAGACTTTTTCTTCTAAAATCTGGATGTCATTGACGA
TAATGTTTATGGAGATAAGGTCTAAGTGCCTAAAAAAATGTACATATACCTGGTTGAAATACAACACTATACATACACACCACCATATAT
ACTAGCTGTTAATCCTATGGAATGGGGTATTGGGAGTGCTTTTTTAATTTTTCATAGTTTTTTTTTAATAAAATGGCATATTTTGCATCT

>In-frame_ENST00000535889_ENST00000295809_TCGA-A8-A07O-01A_MTR_chr1_237001899_-_IFI16_chr1_159021469_length(amino acids)=735AA_start in transcript=22_stop in transcript=2229
MSPALQDLSQPEGLKKTLRDEINAILQKRIMVLDGGMGTMIQREKLNEEHFRGQEFKDHARPLKGNNDILSITQPDVIYQIHKEYLLAGA
DIIETNTFSSTSIAQADYGLEHLAYRMNMCSAGVARKAAEEVTLQTGIKRFVAGALGPTNKTLSVSPSVERPDYRNITFDELVEAYQEQA
KGLLDGGVDILLIETIFDTANAKAALFALQNLFEEKYAPRPIFISGTIVDKSGRTLSGQTGEGFVISVSHGEPLCIGLNCALGAAEMRPF
IEIIGKCTTAYVLCYPNAGLPNTFGDYDETPSMMAKHLKDFAMDGLVNIVGGCCGSTPDHIREIAEAVKNCKPRVPPATAFEGHMLLSGL
EPFRIGPYTNFVNIGERCNVAGSRKFAKLIMAGNYEEALCVAKVQVEMGAQVLDVNMDDGMLDGPSAMTRFCNLIASEPDIAKVPLCIDS
SNFAVIEAGLKCCQGKCIVNSISLKEGEDDFLEKARKIKKYGAAMVVMAFDEEGQLKPRLKTEPEEVSIEDSAQSDLKEVMVLNATESFV
YEPKEQKKMFHATVATENEVFRVKVFNIDLKEKFTPKKIIAIANYVCRNGFLEVYPFTLVADVNADRNMEIPKGLIRSASVTPKINQLCS
QTKGSFVNGVFEVHKKNVRGEFTYYEIQDNTGKMEVVVHGRLTTINCEEGDKLKLTCFELAPKSGNTGELRSVIHSHIKVIKTRKNKKDI

--------------------------------------------------------------
>In-frame_ENST00000535889_ENST00000430894_TCGA-A8-A07O-01A_MTR_chr1_237001899_-_IFI16_chr1_159021469_length(transcript)=2477nt_BP=1537nt
CGCAAGGAGGAGACTCGACAACATGTCACCCGCGCTCCAAGACCTGTCGCAACCCGAAGGTCTGAAGAAAACCCTGCGGGATGAGATCAA
TGCCATTCTGCAGAAGAGGATTATGGTGCTGGATGGAGGGATGGGGACCATGATCCAGCGGGAGAAGCTAAACGAAGAACACTTCCGAGG
TCAGGAATTTAAAGATCATGCCAGGCCGCTGAAAGGCAACAATGACATTTTAAGTATAACTCAGCCTGATGTCATTTACCAAATCCATAA
GGAATACTTGCTGGCTGGGGCAGATATCATTGAAACAAATACTTTTAGCAGCACTAGTATTGCCCAAGCTGACTATGGCCTTGAACACTT
GGCCTACCGGATGAACATGTGCTCTGCAGGAGTGGCCAGAAAAGCTGCCGAGGAGGTAACTCTCCAGACAGGAATTAAGAGGTTTGTGGC
AGGGGCTCTGGGTCCGACTAATAAGACACTCTCTGTGTCCCCATCTGTGGAAAGGCCGGATTATAGGAACATCACATTTGATGAGCTTGT
TGAAGCATACCAAGAGCAGGCCAAAGGACTTCTGGATGGCGGGGTTGATATCTTACTCATTGAAACTATTTTTGATACTGCCAATGCCAA
GGCAGCCTTGTTTGCACTCCAAAATCTTTTTGAGGAGAAATATGCTCCCCGGCCTATCTTTATTTCAGGGACGATCGTTGATAAAAGTGG
GCGGACTCTTTCCGGACAGACAGGAGAGGGATTTGTCATCAGCGTGTCTCATGGAGAACCACTCTGCATTGGATTAAATTGTGCTTTGGG
TGCAGCTGAAATGAGACCTTTTATTGAAATAATTGGAAAATGTACAACAGCCTATGTCCTCTGTTATCCCAATGCAGGTCTTCCCAACAC
CTTTGGTGACTATGATGAAACGCCTTCTATGATGGCCAAGCACCTAAAGGATTTTGCTATGGATGGCTTGGTCAATATAGTTGGAGGATG
CTGTGGGTCAACACCAGATCATATCAGGGAAATTGCTGAAGCTGTGAAAAATTGTAAGCCTAGAGTTCCACCTGCCACTGCTTTTGAAGG
ACATATGTTACTGTCTGGTCTAGAGCCCTTCAGGATTGGACCGTACACCAACTTTGTTAACATTGGAGAGCGCTGTAATGTTGCAGGATC
AAGGAAGTTTGCTAAACTCATCATGGCAGGAAACTATGAAGAAGCCTTGTGTGTTGCCAAAGTGCAGGTGGAAATGGGAGCCCAGGTGTT
GGATGTCAACATGGATGATGGCATGCTAGATGGTCCAAGTGCAATGACCAGATTTTGCAACTTAATTGCTTCCGAGCCAGACATCGCAAA
GGTACCTTTGTGCATCGACTCCTCCAATTTTGCTGTGATTGAAGCTGGGTTAAAGTGCTGCCAAGGGAAGTGCATTGTCAATAGCATTAG
TCTGAAGGAAGGAGAGGACGACTTCTTGGAGAAGGCCAGGAAGATTAAAAAGTATGGAGCTGCTATGGTGGTCATGGCTTTTGATGAAGA
AGGACAGTTGAAACCAAGACTGAAGACTGAACCTGAAGAAGTTTCCATAGAAGACAGTGCCCAGAGTGACCTCAAAGAAGTGATGGTGCT
GAACGCAACAGAATCATTTGTATATGAGCCCAAAGAGCAGAAGAAAATGTTTCATGCCACAGTGGCAACTGAGAATGAAGTCTTCCGAGT
GAAGGTTTTTAATATTGACCTAAAGGAGAAGTTCACCCCAAAGAAGATCATTGCCATAGCAAATTATGTTTGCCGCAATGGGTTCCTGGA
GGTATATCCTTTCACACTTGTGGCTGATGTGAATGCTGACCGAAACATGGAGATCCCAAAAGGATTGATTAGAAGTGCCAGCGTAACTCC
TAAAATCAATCAGCTTTGCTCACAAACTAAAGGAAGTTTTGTGAATGGGGTGTTTGAGGTACATAAGAAAAATGTAAGGGGTGAATTCAC
TTATTATGAAATACAAGATAATACAGGGAAGATGGAAGTGGTGGTGCATGGACGACTGACCACAATCAACTGTGAGGAAGGAGATAAACT
GAAACTCACCTGCTTTGAATTGGCACCGAAAAGTGGGAATACCGGGGAGTTGAGATCTGTAATTCATAGTCACATCAAGGTCATCAAGAC
CAGGAAAAACAAGAAAGACATACTCAATCCTGATTCAAGTATGGAAACTTCACCAGACTTTTTCTTCTAAAATCTGGATGTCATTGACGA
TAATGTTTATGGAGATAAGGTCTAAGTGCCTAAAAAAATGTACATATACCTGGTTGAAATACAACACTATACATACACACCACCATATAT
ACTAGCTGTTAATCCTATGGAATGGGGTATTGGGAGTGCTTTTTTAATTTTTCATAGTTTTTTTTTAATAAAATGGCATATTTTGCATCT

>In-frame_ENST00000535889_ENST00000430894_TCGA-A8-A07O-01A_MTR_chr1_237001899_-_IFI16_chr1_159021469_length(amino acids)=735AA_start in transcript=22_stop in transcript=2229
MSPALQDLSQPEGLKKTLRDEINAILQKRIMVLDGGMGTMIQREKLNEEHFRGQEFKDHARPLKGNNDILSITQPDVIYQIHKEYLLAGA
DIIETNTFSSTSIAQADYGLEHLAYRMNMCSAGVARKAAEEVTLQTGIKRFVAGALGPTNKTLSVSPSVERPDYRNITFDELVEAYQEQA
KGLLDGGVDILLIETIFDTANAKAALFALQNLFEEKYAPRPIFISGTIVDKSGRTLSGQTGEGFVISVSHGEPLCIGLNCALGAAEMRPF
IEIIGKCTTAYVLCYPNAGLPNTFGDYDETPSMMAKHLKDFAMDGLVNIVGGCCGSTPDHIREIAEAVKNCKPRVPPATAFEGHMLLSGL
EPFRIGPYTNFVNIGERCNVAGSRKFAKLIMAGNYEEALCVAKVQVEMGAQVLDVNMDDGMLDGPSAMTRFCNLIASEPDIAKVPLCIDS
SNFAVIEAGLKCCQGKCIVNSISLKEGEDDFLEKARKIKKYGAAMVVMAFDEEGQLKPRLKTEPEEVSIEDSAQSDLKEVMVLNATESFV
YEPKEQKKMFHATVATENEVFRVKVFNIDLKEKFTPKKIIAIANYVCRNGFLEVYPFTLVADVNADRNMEIPKGLIRSASVTPKINQLCS
QTKGSFVNGVFEVHKKNVRGEFTYYEIQDNTGKMEVVVHGRLTTINCEEGDKLKLTCFELAPKSGNTGELRSVIHSHIKVIKTRKNKKDI

--------------------------------------------------------------
>In-frame_ENST00000535889_ENST00000359709_TCGA-A8-A07O-01A_MTR_chr1_237001899_-_IFI16_chr1_159021469_length(transcript)=2477nt_BP=1537nt
CGCAAGGAGGAGACTCGACAACATGTCACCCGCGCTCCAAGACCTGTCGCAACCCGAAGGTCTGAAGAAAACCCTGCGGGATGAGATCAA
TGCCATTCTGCAGAAGAGGATTATGGTGCTGGATGGAGGGATGGGGACCATGATCCAGCGGGAGAAGCTAAACGAAGAACACTTCCGAGG
TCAGGAATTTAAAGATCATGCCAGGCCGCTGAAAGGCAACAATGACATTTTAAGTATAACTCAGCCTGATGTCATTTACCAAATCCATAA
GGAATACTTGCTGGCTGGGGCAGATATCATTGAAACAAATACTTTTAGCAGCACTAGTATTGCCCAAGCTGACTATGGCCTTGAACACTT
GGCCTACCGGATGAACATGTGCTCTGCAGGAGTGGCCAGAAAAGCTGCCGAGGAGGTAACTCTCCAGACAGGAATTAAGAGGTTTGTGGC
AGGGGCTCTGGGTCCGACTAATAAGACACTCTCTGTGTCCCCATCTGTGGAAAGGCCGGATTATAGGAACATCACATTTGATGAGCTTGT
TGAAGCATACCAAGAGCAGGCCAAAGGACTTCTGGATGGCGGGGTTGATATCTTACTCATTGAAACTATTTTTGATACTGCCAATGCCAA
GGCAGCCTTGTTTGCACTCCAAAATCTTTTTGAGGAGAAATATGCTCCCCGGCCTATCTTTATTTCAGGGACGATCGTTGATAAAAGTGG
GCGGACTCTTTCCGGACAGACAGGAGAGGGATTTGTCATCAGCGTGTCTCATGGAGAACCACTCTGCATTGGATTAAATTGTGCTTTGGG
TGCAGCTGAAATGAGACCTTTTATTGAAATAATTGGAAAATGTACAACAGCCTATGTCCTCTGTTATCCCAATGCAGGTCTTCCCAACAC
CTTTGGTGACTATGATGAAACGCCTTCTATGATGGCCAAGCACCTAAAGGATTTTGCTATGGATGGCTTGGTCAATATAGTTGGAGGATG
CTGTGGGTCAACACCAGATCATATCAGGGAAATTGCTGAAGCTGTGAAAAATTGTAAGCCTAGAGTTCCACCTGCCACTGCTTTTGAAGG
ACATATGTTACTGTCTGGTCTAGAGCCCTTCAGGATTGGACCGTACACCAACTTTGTTAACATTGGAGAGCGCTGTAATGTTGCAGGATC
AAGGAAGTTTGCTAAACTCATCATGGCAGGAAACTATGAAGAAGCCTTGTGTGTTGCCAAAGTGCAGGTGGAAATGGGAGCCCAGGTGTT
GGATGTCAACATGGATGATGGCATGCTAGATGGTCCAAGTGCAATGACCAGATTTTGCAACTTAATTGCTTCCGAGCCAGACATCGCAAA
GGTACCTTTGTGCATCGACTCCTCCAATTTTGCTGTGATTGAAGCTGGGTTAAAGTGCTGCCAAGGGAAGTGCATTGTCAATAGCATTAG
TCTGAAGGAAGGAGAGGACGACTTCTTGGAGAAGGCCAGGAAGATTAAAAAGTATGGAGCTGCTATGGTGGTCATGGCTTTTGATGAAGA
AGGACAGTTGAAACCAAGACTGAAGACTGAACCTGAAGAAGTTTCCATAGAAGACAGTGCCCAGAGTGACCTCAAAGAAGTGATGGTGCT
GAACGCAACAGAATCATTTGTATATGAGCCCAAAGAGCAGAAGAAAATGTTTCATGCCACAGTGGCAACTGAGAATGAAGTCTTCCGAGT
GAAGGTTTTTAATATTGACCTAAAGGAGAAGTTCACCCCAAAGAAGATCATTGCCATAGCAAATTATGTTTGCCGCAATGGGTTCCTGGA
GGTATATCCTTTCACACTTGTGGCTGATGTGAATGCTGACCGAAACATGGAGATCCCAAAAGGATTGATTAGAAGTGCCAGCGTAACTCC
TAAAATCAATCAGCTTTGCTCACAAACTAAAGGAAGTTTTGTGAATGGGGTGTTTGAGGTACATAAGAAAAATGTAAGGGGTGAATTCAC
TTATTATGAAATACAAGATAATACAGGGAAGATGGAAGTGGTGGTGCATGGACGACTGACCACAATCAACTGTGAGGAAGGAGATAAACT
GAAACTCACCTGCTTTGAATTGGCACCGAAAAGTGGGAATACCGGGGAGTTGAGATCTGTAATTCATAGTCACATCAAGGTCATCAAGAC
CAGGAAAAACAAGAAAGACATACTCAATCCTGATTCAAGTATGGAAACTTCACCAGACTTTTTCTTCTAAAATCTGGATGTCATTGACGA
TAATGTTTATGGAGATAAGGTCTAAGTGCCTAAAAAAATGTACATATACCTGGTTGAAATACAACACTATACATACACACCACCATATAT
ACTAGCTGTTAATCCTATGGAATGGGGTATTGGGAGTGCTTTTTTAATTTTTCATAGTTTTTTTTTAATAAAATGGCATATTTTGCATCT

>In-frame_ENST00000535889_ENST00000359709_TCGA-A8-A07O-01A_MTR_chr1_237001899_-_IFI16_chr1_159021469_length(amino acids)=735AA_start in transcript=22_stop in transcript=2229
MSPALQDLSQPEGLKKTLRDEINAILQKRIMVLDGGMGTMIQREKLNEEHFRGQEFKDHARPLKGNNDILSITQPDVIYQIHKEYLLAGA
DIIETNTFSSTSIAQADYGLEHLAYRMNMCSAGVARKAAEEVTLQTGIKRFVAGALGPTNKTLSVSPSVERPDYRNITFDELVEAYQEQA
KGLLDGGVDILLIETIFDTANAKAALFALQNLFEEKYAPRPIFISGTIVDKSGRTLSGQTGEGFVISVSHGEPLCIGLNCALGAAEMRPF
IEIIGKCTTAYVLCYPNAGLPNTFGDYDETPSMMAKHLKDFAMDGLVNIVGGCCGSTPDHIREIAEAVKNCKPRVPPATAFEGHMLLSGL
EPFRIGPYTNFVNIGERCNVAGSRKFAKLIMAGNYEEALCVAKVQVEMGAQVLDVNMDDGMLDGPSAMTRFCNLIASEPDIAKVPLCIDS
SNFAVIEAGLKCCQGKCIVNSISLKEGEDDFLEKARKIKKYGAAMVVMAFDEEGQLKPRLKTEPEEVSIEDSAQSDLKEVMVLNATESFV
YEPKEQKKMFHATVATENEVFRVKVFNIDLKEKFTPKKIIAIANYVCRNGFLEVYPFTLVADVNADRNMEIPKGLIRSASVTPKINQLCS
QTKGSFVNGVFEVHKKNVRGEFTYYEIQDNTGKMEVVVHGRLTTINCEEGDKLKLTCFELAPKSGNTGELRSVIHSHIKVIKTRKNKKDI

--------------------------------------------------------------
>In-frame_ENST00000535889_ENST00000448393_TCGA-A8-A07O-01A_MTR_chr1_237001899_-_IFI16_chr1_159021469_length(transcript)=2453nt_BP=1537nt
CGCAAGGAGGAGACTCGACAACATGTCACCCGCGCTCCAAGACCTGTCGCAACCCGAAGGTCTGAAGAAAACCCTGCGGGATGAGATCAA
TGCCATTCTGCAGAAGAGGATTATGGTGCTGGATGGAGGGATGGGGACCATGATCCAGCGGGAGAAGCTAAACGAAGAACACTTCCGAGG
TCAGGAATTTAAAGATCATGCCAGGCCGCTGAAAGGCAACAATGACATTTTAAGTATAACTCAGCCTGATGTCATTTACCAAATCCATAA
GGAATACTTGCTGGCTGGGGCAGATATCATTGAAACAAATACTTTTAGCAGCACTAGTATTGCCCAAGCTGACTATGGCCTTGAACACTT
GGCCTACCGGATGAACATGTGCTCTGCAGGAGTGGCCAGAAAAGCTGCCGAGGAGGTAACTCTCCAGACAGGAATTAAGAGGTTTGTGGC
AGGGGCTCTGGGTCCGACTAATAAGACACTCTCTGTGTCCCCATCTGTGGAAAGGCCGGATTATAGGAACATCACATTTGATGAGCTTGT
TGAAGCATACCAAGAGCAGGCCAAAGGACTTCTGGATGGCGGGGTTGATATCTTACTCATTGAAACTATTTTTGATACTGCCAATGCCAA
GGCAGCCTTGTTTGCACTCCAAAATCTTTTTGAGGAGAAATATGCTCCCCGGCCTATCTTTATTTCAGGGACGATCGTTGATAAAAGTGG
GCGGACTCTTTCCGGACAGACAGGAGAGGGATTTGTCATCAGCGTGTCTCATGGAGAACCACTCTGCATTGGATTAAATTGTGCTTTGGG
TGCAGCTGAAATGAGACCTTTTATTGAAATAATTGGAAAATGTACAACAGCCTATGTCCTCTGTTATCCCAATGCAGGTCTTCCCAACAC
CTTTGGTGACTATGATGAAACGCCTTCTATGATGGCCAAGCACCTAAAGGATTTTGCTATGGATGGCTTGGTCAATATAGTTGGAGGATG
CTGTGGGTCAACACCAGATCATATCAGGGAAATTGCTGAAGCTGTGAAAAATTGTAAGCCTAGAGTTCCACCTGCCACTGCTTTTGAAGG
ACATATGTTACTGTCTGGTCTAGAGCCCTTCAGGATTGGACCGTACACCAACTTTGTTAACATTGGAGAGCGCTGTAATGTTGCAGGATC
AAGGAAGTTTGCTAAACTCATCATGGCAGGAAACTATGAAGAAGCCTTGTGTGTTGCCAAAGTGCAGGTGGAAATGGGAGCCCAGGTGTT
GGATGTCAACATGGATGATGGCATGCTAGATGGTCCAAGTGCAATGACCAGATTTTGCAACTTAATTGCTTCCGAGCCAGACATCGCAAA
GGTACCTTTGTGCATCGACTCCTCCAATTTTGCTGTGATTGAAGCTGGGTTAAAGTGCTGCCAAGGGAAGTGCATTGTCAATAGCATTAG
TCTGAAGGAAGGAGAGGACGACTTCTTGGAGAAGGCCAGGAAGATTAAAAAGTATGGAGCTGCTATGGTGGTCATGGCTTTTGATGAAGA
AGGACAGTTGAAACCAAGACTGAAGACTGAACCTGAAGAAGTTTCCATAGAAGACAGTGCCCAGAGTGACCTCAAAGAAGTGATGGTGCT
GAACGCAACAGAATCATTTGTATATGAGCCCAAAGAGCAGAAGAAAATGTTTCATGCCACAGTGGCAACTGAGAATGAAGTCTTCCGAGT
GAAGGTTTTTAATATTGACCTAAAGGAGAAGTTCACCCCAAAGAAGATCATTGCCATAGCAAATTATGTTTGCCGCAATGGGTTCCTGGA
GGTATATCCTTTCACACTTGTGGCTGATGTGAATGCTGACCGAAACATGGAGATCCCAAAAGGATTGATTAGAAGTGCCAGCGTAACTCC
TAAAATCAATCAGCTTTGCTCACAAACTAAAGGAAGTTTTGTGAATGGGGTGTTTGAGGTACATAAGAAAAATGTAAGGGGTGAATTCAC
TTATTATGAAATACAAGATAATACAGGGAAGATGGAAGTGGTGGTGCATGGACGACTGACCACAATCAACTGTGAGGAAGGAGATAAACT
GAAACTCACCTGCTTTGAATTGGCACCGAAAAGTGGGAATACCGGGGAGTTGAGATCTGTAATTCATAGTCACATCAAGGTCATCAAGAC
CAGGAAAAACAAGAAAGACATACTCAATCCTGATTCAAGTATGGAAACTTCACCAGACTTTTTCTTCTAAAATCTGGATGTCATTGACGA
TAATGTTTATGGAGATAAGGTCTAAGTGCCTAAAAAAATGTACATATACCTGGTTGAAATACAACACTATACATACACACCACCATATAT
ACTAGCTGTTAATCCTATGGAATGGGGTATTGGGAGTGCTTTTTTAATTTTTCATAGTTTTTTTTTAATAAAATGGCATATTTTGCATCT

>In-frame_ENST00000535889_ENST00000448393_TCGA-A8-A07O-01A_MTR_chr1_237001899_-_IFI16_chr1_159021469_length(amino acids)=735AA_start in transcript=22_stop in transcript=2229
MSPALQDLSQPEGLKKTLRDEINAILQKRIMVLDGGMGTMIQREKLNEEHFRGQEFKDHARPLKGNNDILSITQPDVIYQIHKEYLLAGA
DIIETNTFSSTSIAQADYGLEHLAYRMNMCSAGVARKAAEEVTLQTGIKRFVAGALGPTNKTLSVSPSVERPDYRNITFDELVEAYQEQA
KGLLDGGVDILLIETIFDTANAKAALFALQNLFEEKYAPRPIFISGTIVDKSGRTLSGQTGEGFVISVSHGEPLCIGLNCALGAAEMRPF
IEIIGKCTTAYVLCYPNAGLPNTFGDYDETPSMMAKHLKDFAMDGLVNIVGGCCGSTPDHIREIAEAVKNCKPRVPPATAFEGHMLLSGL
EPFRIGPYTNFVNIGERCNVAGSRKFAKLIMAGNYEEALCVAKVQVEMGAQVLDVNMDDGMLDGPSAMTRFCNLIASEPDIAKVPLCIDS
SNFAVIEAGLKCCQGKCIVNSISLKEGEDDFLEKARKIKKYGAAMVVMAFDEEGQLKPRLKTEPEEVSIEDSAQSDLKEVMVLNATESFV
YEPKEQKKMFHATVATENEVFRVKVFNIDLKEKFTPKKIIAIANYVCRNGFLEVYPFTLVADVNADRNMEIPKGLIRSASVTPKINQLCS
QTKGSFVNGVFEVHKKNVRGEFTYYEIQDNTGKMEVVVHGRLTTINCEEGDKLKLTCFELAPKSGNTGELRSVIHSHIKVIKTRKNKKDI

--------------------------------------------------------------

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Fusion Gene PPI Analysis for MTR-IFI16


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneIFI16chr1:237001899chr1:159021469ENST00000295809812571_766555.0786.0TP53 core domain
TgeneIFI16chr1:237001899chr1:159021469ENST00000340979610571_766443.0674.0TP53 core domain
TgeneIFI16chr1:237001899chr1:159021469ENST00000359709711571_766499.0730.0TP53 core domain
TgeneIFI16chr1:237001899chr1:159021469ENST00000368131711571_766499.0730.0TP53 core domain
TgeneIFI16chr1:237001899chr1:159021469ENST00000368132711571_766499.0730.0TP53 core domain
TgeneIFI16chr1:237001899chr1:159021469ENST0000044839359571_766443.0674.0TP53 core domain


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
TgeneIFI16chr1:237001899chr1:159021469ENST00000295809812192_393555.0786.0TP53 C-terminus
TgeneIFI16chr1:237001899chr1:159021469ENST00000340979610192_393443.0674.0TP53 C-terminus
TgeneIFI16chr1:237001899chr1:159021469ENST00000359709711192_393499.0730.0TP53 C-terminus
TgeneIFI16chr1:237001899chr1:159021469ENST00000368131711192_393499.0730.0TP53 C-terminus
TgeneIFI16chr1:237001899chr1:159021469ENST00000368132711192_393499.0730.0TP53 C-terminus
TgeneIFI16chr1:237001899chr1:159021469ENST0000044839359192_393443.0674.0TP53 C-terminus


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for MTR-IFI16


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for MTR-IFI16


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneMTRC1855128Methylcobalamin Deficiency, CblG Type5CTD_human;GENOMICS_ENGLAND;UNIPROT
HgeneMTRC0011570Mental Depression2PSYGENET
HgeneMTRC0011581Depressive disorder2PSYGENET
HgeneMTRC0013221Drug toxicity2CTD_human
HgeneMTRC0041755Adverse reaction to drug2CTD_human
HgeneMTRC0001969Alcoholic Intoxication1PSYGENET
HgeneMTRC0005586Bipolar Disorder1PSYGENET
HgeneMTRC0006142Malignant neoplasm of breast1CTD_human
HgeneMTRC0008924Cleft upper lip1CTD_human
HgeneMTRC0008925Cleft Palate1CTD_human
HgeneMTRC0017178Gastrointestinal Diseases1CTD_human
HgeneMTRC0018939Hematological Disease1CTD_human
HgeneMTRC0021364Male infertility1CTD_human
HgeneMTRC0024299Lymphoma1CTD_human
HgeneMTRC0024301Lymphoma, Follicular1CTD_human
HgeneMTRC0036341Schizophrenia1PSYGENET
HgeneMTRC0036572Seizures1GENOMICS_ENGLAND
HgeneMTRC0079745Lymphoma, Large-Cell, Follicular1CTD_human
HgeneMTRC0079758Lymphoma, Mixed-Cell, Follicular1CTD_human
HgeneMTRC0079765Lymphoma, Small Cleaved-Cell, Follicular1CTD_human
HgeneMTRC0162429Malnutrition1CTD_human
HgeneMTRC0268611Arakawa syndrome 21GENOMICS_ENGLAND
HgeneMTRC0270612Leukoencephalopathy1CTD_human
HgeneMTRC0559031Functional Gastrointestinal Disorders1CTD_human
HgeneMTRC0588008Severe depression1PSYGENET
HgeneMTRC0678222Breast Carcinoma1CTD_human
HgeneMTRC0848676Subfertility, Male1CTD_human
HgeneMTRC0917731Male sterility1CTD_human
HgeneMTRC1257931Mammary Neoplasms, Human1CTD_human
HgeneMTRC1458155Mammary Neoplasms1CTD_human
HgeneMTRC1565321Cholera Infantum1CTD_human
HgeneMTRC1837218Cleft palate, isolated1CTD_human
HgeneMTRC1858991Childhood Ataxia with Central Nervous System Hypomyelinization1CTD_human
HgeneMTRC1866558Neural tube defect, folate-sensitive1CTD_human;GENOMICS_ENGLAND
HgeneMTRC1956130Lymphoma, Follicular, Grade 11CTD_human
HgeneMTRC1956131Lymphoma, Follicular, Grade 31CTD_human
HgeneMTRC1956132Lymphoma, Follicular, Grade 21CTD_human
HgeneMTRC4704874Mammary Carcinoma, Human1CTD_human