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Fusion Gene Summary | |
Fusion Gene ORF analysis | |
Fusion Genomic Features | |
Fusion Protein Features | |
Fusion Gene Sequence | |
Fusion Gene PPI analysis | |
Related Drugs | |
Related Diseases |
Fusion gene:APOA1-HP (FusionGDB2 ID:5585) |
Fusion Gene Summary for APOA1-HP |
Fusion gene summary |
Fusion gene information | Fusion gene name: APOA1-HP | Fusion gene ID: 5585 | Hgene | Tgene | Gene symbol | APOA1 | HP | Gene ID | 335 | 10395 |
Gene name | apolipoprotein A1 | DLC1 Rho GTPase activating protein | |
Synonyms | HPALP2|apo(a) | ARHGAP7|HP|STARD12|p122-RhoGAP | |
Cytomap | 11q23.3 | 8p22 | |
Type of gene | protein-coding | protein-coding | |
Description | apolipoprotein A-Iapo-AIepididymis secretory sperm binding protein | rho GTPase-activating protein 7Rho-GTPase-activating protein 7START domain-containing protein 12StAR-related lipid transfer (START) domain containing 12deleted in liver cancer 1 proteindeleted in liver cancer 1 variant 2deleted in liver cancer varia | |
Modification date | 20200329 | 20200313 | |
UniProtAcc | . | P02790 | |
Ensembl transtripts involved in fusion gene | ENST00000375320, ENST00000359492, ENST00000375329, ENST00000375323, ENST00000236850, | ENST00000570083, ENST00000355906, ENST00000398131, ENST00000569639, ENST00000357763, ENST00000562526, ENST00000565574, | |
Fusion gene scores | * DoF score | 9 X 5 X 3=135 | 14 X 11 X 3=462 |
# samples | 9 | 13 | |
** MAII score | log2(9/135*10)=-0.584962500721156 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(13/462*10)=-1.8293812283876 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
Context | PubMed: APOA1 [Title/Abstract] AND HP [Title/Abstract] AND fusion [Title/Abstract] | ||
Most frequent breakpoint | APOA1(116706959)-HP(72094565), # samples:1 | ||
Anticipated loss of major functional domain due to fusion event. |
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
Partner | Gene | GO ID | GO term | PubMed ID |
Hgene | APOA1 | GO:0002740 | negative regulation of cytokine secretion involved in immune response | 12458630 |
Hgene | APOA1 | GO:0006656 | phosphatidylcholine biosynthetic process | 4335615 |
Hgene | APOA1 | GO:0007179 | transforming growth factor beta receptor signaling pathway | 23726972 |
Hgene | APOA1 | GO:0007186 | G protein-coupled receptor signaling pathway | 16443932 |
Hgene | APOA1 | GO:0007229 | integrin-mediated signaling pathway | 23726972 |
Hgene | APOA1 | GO:0010804 | negative regulation of tumor necrosis factor-mediated signaling pathway | 21571275 |
Hgene | APOA1 | GO:0010873 | positive regulation of cholesterol esterification | 4335615 |
Hgene | APOA1 | GO:0010875 | positive regulation of cholesterol efflux | 27472885 |
Hgene | APOA1 | GO:0010903 | negative regulation of very-low-density lipoprotein particle remodeling | 14967812 |
Hgene | APOA1 | GO:0018158 | protein oxidation | 12576517 |
Hgene | APOA1 | GO:0018206 | peptidyl-methionine modification | 12576517 |
Hgene | APOA1 | GO:0030301 | cholesterol transport | 10559507 |
Hgene | APOA1 | GO:0032489 | regulation of Cdc42 protein signal transduction | 16443932 |
Hgene | APOA1 | GO:0033344 | cholesterol efflux | 11162594|14703508|15358760|16443932|21481393 |
Hgene | APOA1 | GO:0033700 | phospholipid efflux | 11162594|14703508 |
Hgene | APOA1 | GO:0034115 | negative regulation of heterotypic cell-cell adhesion | 21571275 |
Hgene | APOA1 | GO:0034375 | high-density lipoprotein particle remodeling | 21481393 |
Hgene | APOA1 | GO:0034380 | high-density lipoprotein particle assembly | 190223 |
Hgene | APOA1 | GO:0035025 | positive regulation of Rho protein signal transduction | 23726972 |
Hgene | APOA1 | GO:0042632 | cholesterol homeostasis | 21571275 |
Hgene | APOA1 | GO:0050713 | negative regulation of interleukin-1 beta secretion | 12458630 |
Hgene | APOA1 | GO:0050728 | negative regulation of inflammatory response | 21571275 |
Hgene | APOA1 | GO:0050766 | positive regulation of phagocytosis | 20495215 |
Hgene | APOA1 | GO:0050821 | protein stabilization | 17655203|20495215 |
Hgene | APOA1 | GO:0050919 | negative chemotaxis | 23726972 |
Hgene | APOA1 | GO:0051345 | positive regulation of hydrolase activity | 7638166 |
Hgene | APOA1 | GO:0051496 | positive regulation of stress fiber assembly | 23726972 |
Hgene | APOA1 | GO:0055091 | phospholipid homeostasis | 21571275 |
Hgene | APOA1 | GO:0060354 | negative regulation of cell adhesion molecule production | 21571275 |
Hgene | APOA1 | GO:0060761 | negative regulation of response to cytokine stimulus | 21571275 |
Hgene | APOA1 | GO:0070328 | triglyceride homeostasis | 21571275 |
Hgene | APOA1 | GO:0070371 | ERK1 and ERK2 cascade | 23726972 |
Hgene | APOA1 | GO:1900026 | positive regulation of substrate adhesion-dependent cell spreading | 23726972 |
Hgene | APOA1 | GO:1902995 | positive regulation of phospholipid efflux | 27472885 |
Tgene | HP | GO:0006915 | apoptotic process | 17292327 |
Tgene | HP | GO:0006919 | activation of cysteine-type endopeptidase activity involved in apoptotic process | 17888903 |
Tgene | HP | GO:0008285 | negative regulation of cell proliferation | 12545165|17932950 |
Tgene | HP | GO:0030336 | negative regulation of cell migration | 17932950|19158340 |
Tgene | HP | GO:0035307 | positive regulation of protein dephosphorylation | 17292327 |
Tgene | HP | GO:0051497 | negative regulation of stress fiber assembly | 17932950 |
Tgene | HP | GO:0051895 | negative regulation of focal adhesion assembly | 19158340 |
Tgene | HP | GO:1900119 | positive regulation of execution phase of apoptosis | 17888903 |
Fusion gene breakpoints across APOA1 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
Fusion gene breakpoints across HP (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
ChimerDB4 | Non-Cancer | ERR315463 | APOA1 | chr11 | 116706959 | - | HP | chr16 | 72094565 | + |
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Fusion Gene ORF analysis for APOA1-HP |
Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
intron-3CDS | ENST00000375320 | ENST00000570083 | APOA1 | chr11 | 116706959 | - | HP | chr16 | 72094565 | + |
intron-3CDS | ENST00000375320 | ENST00000355906 | APOA1 | chr11 | 116706959 | - | HP | chr16 | 72094565 | + |
intron-3CDS | ENST00000375320 | ENST00000398131 | APOA1 | chr11 | 116706959 | - | HP | chr16 | 72094565 | + |
intron-intron | ENST00000375320 | ENST00000569639 | APOA1 | chr11 | 116706959 | - | HP | chr16 | 72094565 | + |
intron-intron | ENST00000375320 | ENST00000357763 | APOA1 | chr11 | 116706959 | - | HP | chr16 | 72094565 | + |
intron-intron | ENST00000375320 | ENST00000562526 | APOA1 | chr11 | 116706959 | - | HP | chr16 | 72094565 | + |
intron-intron | ENST00000375320 | ENST00000565574 | APOA1 | chr11 | 116706959 | - | HP | chr16 | 72094565 | + |
intron-3CDS | ENST00000359492 | ENST00000570083 | APOA1 | chr11 | 116706959 | - | HP | chr16 | 72094565 | + |
intron-3CDS | ENST00000359492 | ENST00000355906 | APOA1 | chr11 | 116706959 | - | HP | chr16 | 72094565 | + |
intron-3CDS | ENST00000359492 | ENST00000398131 | APOA1 | chr11 | 116706959 | - | HP | chr16 | 72094565 | + |
intron-intron | ENST00000359492 | ENST00000569639 | APOA1 | chr11 | 116706959 | - | HP | chr16 | 72094565 | + |
intron-intron | ENST00000359492 | ENST00000357763 | APOA1 | chr11 | 116706959 | - | HP | chr16 | 72094565 | + |
intron-intron | ENST00000359492 | ENST00000562526 | APOA1 | chr11 | 116706959 | - | HP | chr16 | 72094565 | + |
intron-intron | ENST00000359492 | ENST00000565574 | APOA1 | chr11 | 116706959 | - | HP | chr16 | 72094565 | + |
intron-3CDS | ENST00000375329 | ENST00000570083 | APOA1 | chr11 | 116706959 | - | HP | chr16 | 72094565 | + |
intron-3CDS | ENST00000375329 | ENST00000355906 | APOA1 | chr11 | 116706959 | - | HP | chr16 | 72094565 | + |
intron-3CDS | ENST00000375329 | ENST00000398131 | APOA1 | chr11 | 116706959 | - | HP | chr16 | 72094565 | + |
intron-intron | ENST00000375329 | ENST00000569639 | APOA1 | chr11 | 116706959 | - | HP | chr16 | 72094565 | + |
intron-intron | ENST00000375329 | ENST00000357763 | APOA1 | chr11 | 116706959 | - | HP | chr16 | 72094565 | + |
intron-intron | ENST00000375329 | ENST00000562526 | APOA1 | chr11 | 116706959 | - | HP | chr16 | 72094565 | + |
intron-intron | ENST00000375329 | ENST00000565574 | APOA1 | chr11 | 116706959 | - | HP | chr16 | 72094565 | + |
intron-3CDS | ENST00000375323 | ENST00000570083 | APOA1 | chr11 | 116706959 | - | HP | chr16 | 72094565 | + |
intron-3CDS | ENST00000375323 | ENST00000355906 | APOA1 | chr11 | 116706959 | - | HP | chr16 | 72094565 | + |
intron-3CDS | ENST00000375323 | ENST00000398131 | APOA1 | chr11 | 116706959 | - | HP | chr16 | 72094565 | + |
intron-intron | ENST00000375323 | ENST00000569639 | APOA1 | chr11 | 116706959 | - | HP | chr16 | 72094565 | + |
intron-intron | ENST00000375323 | ENST00000357763 | APOA1 | chr11 | 116706959 | - | HP | chr16 | 72094565 | + |
intron-intron | ENST00000375323 | ENST00000562526 | APOA1 | chr11 | 116706959 | - | HP | chr16 | 72094565 | + |
intron-intron | ENST00000375323 | ENST00000565574 | APOA1 | chr11 | 116706959 | - | HP | chr16 | 72094565 | + |
intron-3CDS | ENST00000236850 | ENST00000570083 | APOA1 | chr11 | 116706959 | - | HP | chr16 | 72094565 | + |
intron-3CDS | ENST00000236850 | ENST00000355906 | APOA1 | chr11 | 116706959 | - | HP | chr16 | 72094565 | + |
intron-3CDS | ENST00000236850 | ENST00000398131 | APOA1 | chr11 | 116706959 | - | HP | chr16 | 72094565 | + |
intron-intron | ENST00000236850 | ENST00000569639 | APOA1 | chr11 | 116706959 | - | HP | chr16 | 72094565 | + |
intron-intron | ENST00000236850 | ENST00000357763 | APOA1 | chr11 | 116706959 | - | HP | chr16 | 72094565 | + |
intron-intron | ENST00000236850 | ENST00000562526 | APOA1 | chr11 | 116706959 | - | HP | chr16 | 72094565 | + |
intron-intron | ENST00000236850 | ENST00000565574 | APOA1 | chr11 | 116706959 | - | HP | chr16 | 72094565 | + |
ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
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Fusion Genomic Features for APOA1-HP |
FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for APOA1-HP |
Go to FGviewer for the breakpoints of :-: - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. |
Main function of each fusion partner protein. (from UniProt) |
Hgene | Tgene |
. | HP |
FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes. | FUNCTION: Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation. |
Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
- In-frame and retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
- In-frame and not-retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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Fusion Gene Sequence for APOA1-HP |
For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
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Fusion Gene PPI Analysis for APOA1-HP |
Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
Hgene | Hgene's interactors | Tgene | Tgene's interactors |
- Retained PPIs in in-frame fusion. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
- Lost PPIs in in-frame fusion. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
- Retained PPIs, but lost function due to frame-shift fusion. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for APOA1-HP |
Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Tgene | HP | P02790 | DB14548 | Zinc sulfate, unspecified form | Ligand | Small molecule | Approved|Experimental |
Tgene | HP | P02790 | DB14533 | Zinc chloride | Ligand | Small molecule | Approved|Investigational |
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Related Diseases for APOA1-HP |
Diseases associated with fusion partners. (DisGeNet 4.0) |
Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Hgene | APOA1 | C0268389 | Amyloidosis, familial visceral | 8 | CTD_human;GENOMICS_ENGLAND;UNIPROT |
Hgene | APOA1 | C1704429 | Hypoalphalipoproteinemia, Familial | 3 | GENOMICS_ENGLAND;ORPHANET |
Hgene | APOA1 | C0024623 | Malignant neoplasm of stomach | 2 | CTD_human |
Hgene | APOA1 | C0038356 | Stomach Neoplasms | 2 | CTD_human |
Hgene | APOA1 | C0342898 | Apolipoprotein A-I deficiency | 2 | ORPHANET |
Hgene | APOA1 | C1708349 | Hereditary Diffuse Gastric Cancer | 2 | CTD_human |
Hgene | APOA1 | C0001418 | Adenocarcinoma | 1 | CTD_human |
Hgene | APOA1 | C0003129 | Anoxemia | 1 | CTD_human |
Hgene | APOA1 | C0003130 | Anoxia | 1 | CTD_human |
Hgene | APOA1 | C0004943 | Behcet Syndrome | 1 | CTD_human |
Hgene | APOA1 | C0010054 | Coronary Arteriosclerosis | 1 | CTD_human |
Hgene | APOA1 | C0011609 | Drug Eruptions | 1 | CTD_human |
Hgene | APOA1 | C0013604 | Edema | 1 | CTD_human |
Hgene | APOA1 | C0017665 | Membranous glomerulonephritis | 1 | CTD_human |
Hgene | APOA1 | C0019193 | Hepatitis, Toxic | 1 | CTD_human |
Hgene | APOA1 | C0019693 | HIV Infections | 1 | CTD_human |
Hgene | APOA1 | C0020538 | Hypertensive disease | 1 | CTD_human |
Hgene | APOA1 | C0021368 | Inflammation | 1 | CTD_human |
Hgene | APOA1 | C0024121 | Lung Neoplasms | 1 | CTD_human |
Hgene | APOA1 | C0038454 | Cerebrovascular accident | 1 | CTD_human |
Hgene | APOA1 | C0079221 | Determination of Death | 1 | CTD_human |
Hgene | APOA1 | C0086445 | Idiopathic Membranous Glomerulonephritis | 1 | CTD_human |
Hgene | APOA1 | C0151603 | Anasarca | 1 | CTD_human |
Hgene | APOA1 | C0152013 | Adenocarcinoma of lung (disorder) | 1 | CTD_human |
Hgene | APOA1 | C0154251 | Lipid Metabolism Disorders | 1 | CTD_human |
Hgene | APOA1 | C0205641 | Adenocarcinoma, Basal Cell | 1 | CTD_human |
Hgene | APOA1 | C0205642 | Adenocarcinoma, Oxyphilic | 1 | CTD_human |
Hgene | APOA1 | C0205643 | Carcinoma, Cribriform | 1 | CTD_human |
Hgene | APOA1 | C0205644 | Carcinoma, Granular Cell | 1 | CTD_human |
Hgene | APOA1 | C0205645 | Adenocarcinoma, Tubular | 1 | CTD_human |
Hgene | APOA1 | C0242184 | Hypoxia | 1 | CTD_human |
Hgene | APOA1 | C0242379 | Malignant neoplasm of lung | 1 | CTD_human |
Hgene | APOA1 | C0242488 | Acute Lung Injury | 1 | CTD_human |
Hgene | APOA1 | C0345967 | Malignant mesothelioma | 1 | CTD_human |
Hgene | APOA1 | C0376297 | Cardiac Death | 1 | CTD_human |
Hgene | APOA1 | C0406537 | Morbilliform Drug Reaction | 1 | CTD_human |
Hgene | APOA1 | C0700292 | Hypoxemia | 1 | CTD_human |
Hgene | APOA1 | C0751956 | Acute Cerebrovascular Accidents | 1 | CTD_human |
Hgene | APOA1 | C0853897 | Diabetic Cardiomyopathies | 1 | CTD_human |
Hgene | APOA1 | C0860207 | Drug-Induced Liver Disease | 1 | CTD_human |
Hgene | APOA1 | C1262760 | Hepatitis, Drug-Induced | 1 | CTD_human |
Hgene | APOA1 | C1704378 | Heymann Nephritis | 1 | CTD_human |
Hgene | APOA1 | C1848533 | Ataxia with vitamin E deficiency | 1 | CTD_human |
Hgene | APOA1 | C1956346 | Coronary Artery Disease | 1 | CTD_human |
Hgene | APOA1 | C2239176 | Liver carcinoma | 1 | CTD_human |
Hgene | APOA1 | C2362324 | Pediatric Obesity | 1 | CTD_human |
Hgene | APOA1 | C3658290 | Drug-Induced Acute Liver Injury | 1 | CTD_human |
Hgene | APOA1 | C4087498 | Familial LCAT deficiency | 1 | GENOMICS_ENGLAND |
Hgene | APOA1 | C4277682 | Chemical and Drug Induced Liver Injury | 1 | CTD_human |
Hgene | APOA1 | C4279912 | Chemically-Induced Liver Toxicity | 1 | CTD_human |
Hgene | APOA1 | C4317171 | Adolescent Obesity | 1 | CTD_human |
Hgene | APOA1 | C4505456 | HIV Coinfection | 1 | CTD_human |
Hgene | APOA1 | C4521075 | Childhood Overweight | 1 | CTD_human |
Hgene | APOA1 | C4553478 | Infantile Obesity | 1 | CTD_human |
Hgene | APOA1 | C4704955 | Infant Overweight | 1 | CTD_human |
Hgene | APOA1 | C4704956 | Adolescent Overweight | 1 | CTD_human |
Tgene | HP | C0041696 | Unipolar Depression | 4 | PSYGENET |
Tgene | HP | C0011570 | Mental Depression | 3 | PSYGENET |
Tgene | HP | C0011581 | Depressive disorder | 3 | PSYGENET |
Tgene | HP | C0027051 | Myocardial Infarction | 3 | CTD_human |
Tgene | HP | C1269683 | Major Depressive Disorder | 3 | PSYGENET |
Tgene | HP | C0024530 | Malaria | 2 | CTD_human |
Tgene | HP | C0525045 | Mood Disorders | 2 | PSYGENET |
Tgene | HP | C0001723 | Affective Disorders, Psychotic | 1 | PSYGENET |
Tgene | HP | C0002871 | Anemia | 1 | CTD_human |
Tgene | HP | C0002895 | Anemia, Sickle Cell | 1 | CTD_human |
Tgene | HP | C0003864 | Arthritis | 1 | CTD_human |
Tgene | HP | C0004153 | Atherosclerosis | 1 | CTD_human |
Tgene | HP | C0004364 | Autoimmune Diseases | 1 | CTD_human |
Tgene | HP | C0006142 | Malignant neoplasm of breast | 1 | CTD_human |
Tgene | HP | C0007222 | Cardiovascular Diseases | 1 | CTD_human |
Tgene | HP | C0011854 | Diabetes Mellitus, Insulin-Dependent | 1 | CTD_human |
Tgene | HP | C0011860 | Diabetes Mellitus, Non-Insulin-Dependent | 1 | CTD_human |
Tgene | HP | C0011875 | Diabetic Angiopathies | 1 | CTD_human |
Tgene | HP | C0013221 | Drug toxicity | 1 | CTD_human |
Tgene | HP | C0016479 | Food Poisoning | 1 | CTD_human |
Tgene | HP | C0017416 | Genital Neoplasms, Female | 1 | CTD_human |
Tgene | HP | C0018995 | Hemochromatosis | 1 | CTD_human |
Tgene | HP | C0019054 | Hemolysis (disorder) | 1 | CTD_human |
Tgene | HP | C0019163 | Hepatitis B | 1 | CTD_human |
Tgene | HP | C0019693 | HIV Infections | 1 | CTD_human |
Tgene | HP | C0020517 | Hypersensitivity | 1 | CTD_human |
Tgene | HP | C0020538 | Hypertensive disease | 1 | CTD_human |
Tgene | HP | C0022660 | Kidney Failure, Acute | 1 | CTD_human |
Tgene | HP | C0023418 | leukemia | 1 | CTD_human |
Tgene | HP | C0025945 | Microangiopathy, Diabetic | 1 | CTD_human |
Tgene | HP | C0035305 | Retinal Detachment | 1 | CTD_human |
Tgene | HP | C0036341 | Schizophrenia | 1 | CTD_human |
Tgene | HP | C0041296 | Tuberculosis | 1 | CTD_human |
Tgene | HP | C0041755 | Adverse reaction to drug | 1 | CTD_human |
Tgene | HP | C0085397 | Pasteurellaceae Infections | 1 | CTD_human |
Tgene | HP | C0162323 | Polyarthritis | 1 | CTD_human |
Tgene | HP | C0205734 | Diabetes, Autoimmune | 1 | CTD_human |
Tgene | HP | C0235574 | Intravascular hemolysis | 1 | CTD_human |
Tgene | HP | C0242339 | Dyslipidemias | 1 | CTD_human |
Tgene | HP | C0312854 | Extravascular Hemolysis | 1 | CTD_human |
Tgene | HP | C0339546 | Retinal Pigment Epithelial Detachment | 1 | CTD_human |
Tgene | HP | C0341934 | Transient hypertension of pregnancy | 1 | CTD_human |
Tgene | HP | C0342257 | Complications of Diabetes Mellitus | 1 | CTD_human |
Tgene | HP | C0342302 | Brittle diabetes | 1 | CTD_human |
Tgene | HP | C0392514 | Hereditary hemochromatosis | 1 | CTD_human |
Tgene | HP | C0524909 | Hepatitis B, Chronic | 1 | CTD_human |
Tgene | HP | C0524910 | Hepatitis C, Chronic | 1 | CTD_human |
Tgene | HP | C0598784 | Dyslipoproteinemias | 1 | CTD_human |
Tgene | HP | C0678222 | Breast Carcinoma | 1 | CTD_human |
Tgene | HP | C0679360 | Foodborne Disease | 1 | CTD_human |
Tgene | HP | C0852036 | Pregnancy associated hypertension | 1 | CTD_human |
Tgene | HP | C1257931 | Mammary Neoplasms, Human | 1 | CTD_human |
Tgene | HP | C1458155 | Mammary Neoplasms | 1 | CTD_human |
Tgene | HP | C1527304 | Allergic Reaction | 1 | CTD_human |
Tgene | HP | C1563937 | Atherogenesis | 1 | CTD_human |
Tgene | HP | C1565662 | Acute Kidney Insufficiency | 1 | CTD_human |
Tgene | HP | C2609414 | Acute kidney injury | 1 | CTD_human |
Tgene | HP | C3279786 | ANHAPTOGLOBINEMIA | 1 | UNIPROT |
Tgene | HP | C3837958 | Diabetes Mellitus, Ketosis-Prone | 1 | CTD_human |
Tgene | HP | C4505456 | HIV Coinfection | 1 | CTD_human |
Tgene | HP | C4554117 | Diabetes Mellitus, Sudden-Onset | 1 | CTD_human |
Tgene | HP | C4704874 | Mammary Carcinoma, Human | 1 | CTD_human |