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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:NADK-MROH1 (FusionGDB2 ID:56763)

Fusion Gene Summary for NADK-MROH1

check button Fusion gene summary
Fusion gene informationFusion gene name: NADK-MROH1
Fusion gene ID: 56763
HgeneTgene
Gene symbol

NADK

MROH1

Gene ID

65220

727957

Gene nameNAD kinasemaestro heat like repeat family member 1
SynonymsdJ283E3.1HEATR7A
Cytomap

1p36.33

8q24.3

Type of geneprotein-codingprotein-coding
DescriptionNAD kinasepoly(P)/ATP NAD kinasemaestro heat-like repeat-containing protein family member 1HEAT repeat containing 7AHEAT repeat-containing protein 7A
Modification date2020032720200320
UniProtAcc.

Q8NDA8

Ensembl transtripts involved in fusion geneENST00000341426, ENST00000341991, 
ENST00000378625, ENST00000344463, 
ENST00000492768, ENST00000342348, 
ENST00000423230, ENST00000398656, 
ENST00000534366, ENST00000528919, 
ENST00000326134, ENST00000527071, 
ENST00000544576, 
Fusion gene scores* DoF score11 X 10 X 7=7707 X 7 X 6=294
# samples 137
** MAII scorelog2(13/770*10)=-2.56634682255381
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(7/294*10)=-2.0703893278914
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: NADK [Title/Abstract] AND MROH1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointNADK(1696667)-MROH1(145245687), # samples:2
Anticipated loss of major functional domain due to fusion event.NADK-MROH1 seems lost the major protein functional domain in Hgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
NADK-MROH1 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across NADK (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across MROH1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4OVTCGA-04-1361-01ANADKchr1

1696667

-MROH1chr8

145245687

+
ChimerDB4OVTCGA-04-1361-01ANADKchr1

1696667

-MROH1chr8

145245687

+


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Fusion Gene ORF analysis for NADK-MROH1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000341426ENST00000423230NADKchr1

1696667

-MROH1chr8

145245687

+
Frame-shiftENST00000341426ENST00000398656NADKchr1

1696667

-MROH1chr8

145245687

+
Frame-shiftENST00000341426ENST00000534366NADKchr1

1696667

-MROH1chr8

145245687

+
Frame-shiftENST00000341426ENST00000528919NADKchr1

1696667

-MROH1chr8

145245687

+
Frame-shiftENST00000341426ENST00000326134NADKchr1

1696667

-MROH1chr8

145245687

+
5CDS-intronENST00000341426ENST00000527071NADKchr1

1696667

-MROH1chr8

145245687

+
5CDS-intronENST00000341426ENST00000544576NADKchr1

1696667

-MROH1chr8

145245687

+
Frame-shiftENST00000341991ENST00000423230NADKchr1

1696667

-MROH1chr8

145245687

+
Frame-shiftENST00000341991ENST00000398656NADKchr1

1696667

-MROH1chr8

145245687

+
Frame-shiftENST00000341991ENST00000534366NADKchr1

1696667

-MROH1chr8

145245687

+
Frame-shiftENST00000341991ENST00000528919NADKchr1

1696667

-MROH1chr8

145245687

+
Frame-shiftENST00000341991ENST00000326134NADKchr1

1696667

-MROH1chr8

145245687

+
5CDS-intronENST00000341991ENST00000527071NADKchr1

1696667

-MROH1chr8

145245687

+
5CDS-intronENST00000341991ENST00000544576NADKchr1

1696667

-MROH1chr8

145245687

+
In-frameENST00000378625ENST00000423230NADKchr1

1696667

-MROH1chr8

145245687

+
In-frameENST00000378625ENST00000398656NADKchr1

1696667

-MROH1chr8

145245687

+
In-frameENST00000378625ENST00000534366NADKchr1

1696667

-MROH1chr8

145245687

+
In-frameENST00000378625ENST00000528919NADKchr1

1696667

-MROH1chr8

145245687

+
In-frameENST00000378625ENST00000326134NADKchr1

1696667

-MROH1chr8

145245687

+
5CDS-intronENST00000378625ENST00000527071NADKchr1

1696667

-MROH1chr8

145245687

+
5CDS-intronENST00000378625ENST00000544576NADKchr1

1696667

-MROH1chr8

145245687

+
Frame-shiftENST00000344463ENST00000423230NADKchr1

1696667

-MROH1chr8

145245687

+
Frame-shiftENST00000344463ENST00000398656NADKchr1

1696667

-MROH1chr8

145245687

+
Frame-shiftENST00000344463ENST00000534366NADKchr1

1696667

-MROH1chr8

145245687

+
Frame-shiftENST00000344463ENST00000528919NADKchr1

1696667

-MROH1chr8

145245687

+
Frame-shiftENST00000344463ENST00000326134NADKchr1

1696667

-MROH1chr8

145245687

+
5CDS-intronENST00000344463ENST00000527071NADKchr1

1696667

-MROH1chr8

145245687

+
5CDS-intronENST00000344463ENST00000544576NADKchr1

1696667

-MROH1chr8

145245687

+
5UTR-3CDSENST00000492768ENST00000423230NADKchr1

1696667

-MROH1chr8

145245687

+
5UTR-3CDSENST00000492768ENST00000398656NADKchr1

1696667

-MROH1chr8

145245687

+
5UTR-3CDSENST00000492768ENST00000534366NADKchr1

1696667

-MROH1chr8

145245687

+
5UTR-3CDSENST00000492768ENST00000528919NADKchr1

1696667

-MROH1chr8

145245687

+
5UTR-3CDSENST00000492768ENST00000326134NADKchr1

1696667

-MROH1chr8

145245687

+
5UTR-intronENST00000492768ENST00000527071NADKchr1

1696667

-MROH1chr8

145245687

+
5UTR-intronENST00000492768ENST00000544576NADKchr1

1696667

-MROH1chr8

145245687

+
intron-3CDSENST00000342348ENST00000423230NADKchr1

1696667

-MROH1chr8

145245687

+
intron-3CDSENST00000342348ENST00000398656NADKchr1

1696667

-MROH1chr8

145245687

+
intron-3CDSENST00000342348ENST00000534366NADKchr1

1696667

-MROH1chr8

145245687

+
intron-3CDSENST00000342348ENST00000528919NADKchr1

1696667

-MROH1chr8

145245687

+
intron-3CDSENST00000342348ENST00000326134NADKchr1

1696667

-MROH1chr8

145245687

+
intron-intronENST00000342348ENST00000527071NADKchr1

1696667

-MROH1chr8

145245687

+
intron-intronENST00000342348ENST00000544576NADKchr1

1696667

-MROH1chr8

145245687

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000378625NADKchr11696667-ENST00000423230MROH1chr8145245687+14373842601090276
ENST00000378625NADKchr11696667-ENST00000398656MROH1chr8145245687+474838426047471496
ENST00000378625NADKchr11696667-ENST00000534366MROH1chr8145245687+479038426047201486
ENST00000378625NADKchr11696667-ENST00000528919MROH1chr8145245687+493538426047471495
ENST00000378625NADKchr11696667-ENST00000326134MROH1chr8145245687+494838426047471495

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000378625ENST00000423230NADKchr11696667-MROH1chr8145245687+0.0611434060.93885666
ENST00000378625ENST00000398656NADKchr11696667-MROH1chr8145245687+0.0073271580.99267286
ENST00000378625ENST00000534366NADKchr11696667-MROH1chr8145245687+0.0077268650.99227315
ENST00000378625ENST00000528919NADKchr11696667-MROH1chr8145245687+0.0068424950.99315757
ENST00000378625ENST00000326134NADKchr11696667-MROH1chr8145245687+0.0068373340.99316263

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Fusion Genomic Features for NADK-MROH1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
NADKchr11696666-MROH1chr8145245686+1.52E-111
NADKchr11696666-MROH1chr8145245686+1.52E-111

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for NADK-MROH1


check button Go to

FGviewer for the breakpoints of chr1:1696667-chr8:145245687

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.MROH1

Q8NDA8

FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneMROH1chr1:1696667chr8:145245687ENST000003261344421048_1086187.333333333333341642.0RepeatNote=HEAT 5
TgeneMROH1chr1:1696667chr8:145245687ENST000003261344421358_1396187.333333333333341642.0RepeatNote=HEAT 6
TgeneMROH1chr1:1696667chr8:145245687ENST000003261344421605_1641187.333333333333341642.0RepeatNote=HEAT 7
TgeneMROH1chr1:1696667chr8:145245687ENST00000326134442344_382187.333333333333341642.0RepeatNote=HEAT 3
TgeneMROH1chr1:1696667chr8:145245687ENST00000326134442385_423187.333333333333341642.0RepeatNote=HEAT 4
TgeneMROH1chr1:1696667chr8:145245687ENST000003986565431048_1086187.333333333333341642.0RepeatNote=HEAT 5
TgeneMROH1chr1:1696667chr8:145245687ENST000003986565431358_1396187.333333333333341642.0RepeatNote=HEAT 6
TgeneMROH1chr1:1696667chr8:145245687ENST000003986565431605_1641187.333333333333341642.0RepeatNote=HEAT 7
TgeneMROH1chr1:1696667chr8:145245687ENST00000398656543344_382187.333333333333341642.0RepeatNote=HEAT 3
TgeneMROH1chr1:1696667chr8:145245687ENST00000398656543385_423187.333333333333341642.0RepeatNote=HEAT 4
TgeneMROH1chr1:1696667chr8:145245687ENST000004232305121048_1086187.33333333333334423.0RepeatNote=HEAT 5
TgeneMROH1chr1:1696667chr8:145245687ENST000004232305121358_1396187.33333333333334423.0RepeatNote=HEAT 6
TgeneMROH1chr1:1696667chr8:145245687ENST000004232305121605_1641187.33333333333334423.0RepeatNote=HEAT 7
TgeneMROH1chr1:1696667chr8:145245687ENST00000423230512344_382187.33333333333334423.0RepeatNote=HEAT 3
TgeneMROH1chr1:1696667chr8:145245687ENST00000423230512385_423187.33333333333334423.0RepeatNote=HEAT 4
TgeneMROH1chr1:1696667chr8:145245687ENST000005289195431048_1086187.333333333333341642.0RepeatNote=HEAT 5
TgeneMROH1chr1:1696667chr8:145245687ENST000005289195431358_1396187.333333333333341642.0RepeatNote=HEAT 6
TgeneMROH1chr1:1696667chr8:145245687ENST000005289195431605_1641187.333333333333341642.0RepeatNote=HEAT 7
TgeneMROH1chr1:1696667chr8:145245687ENST00000528919543344_382187.333333333333341642.0RepeatNote=HEAT 3
TgeneMROH1chr1:1696667chr8:145245687ENST00000528919543385_423187.333333333333341642.0RepeatNote=HEAT 4
TgeneMROH1chr1:1696667chr8:145245687ENST000005445760261048_10860616.0RepeatNote=HEAT 5
TgeneMROH1chr1:1696667chr8:145245687ENST000005445760261358_13960616.0RepeatNote=HEAT 6
TgeneMROH1chr1:1696667chr8:145245687ENST00000544576026159_1980616.0RepeatNote=HEAT 2
TgeneMROH1chr1:1696667chr8:145245687ENST000005445760261605_16410616.0RepeatNote=HEAT 7
TgeneMROH1chr1:1696667chr8:145245687ENST00000544576026344_3820616.0RepeatNote=HEAT 3
TgeneMROH1chr1:1696667chr8:145245687ENST00000544576026385_4230616.0RepeatNote=HEAT 4
TgeneMROH1chr1:1696667chr8:145245687ENST000005445760263_410616.0RepeatNote=HEAT 1

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNADKchr1:1696667chr8:145245687ENST00000341426-212326_33359.666666666666664447.0Compositional biasNote=Poly-Ala
HgeneNADKchr1:1696667chr8:145245687ENST00000341426-212437_44559.666666666666664447.0Compositional biasNote=Poly-Glu
HgeneNADKchr1:1696667chr8:145245687ENST00000341991-212326_33359.666666666666664447.0Compositional biasNote=Poly-Ala
HgeneNADKchr1:1696667chr8:145245687ENST00000341991-212437_44559.666666666666664447.0Compositional biasNote=Poly-Glu
HgeneNADKchr1:1696667chr8:145245687ENST00000344463-214326_33359.666666666666664592.0Compositional biasNote=Poly-Ala
HgeneNADKchr1:1696667chr8:145245687ENST00000344463-214437_44559.666666666666664592.0Compositional biasNote=Poly-Glu
HgeneNADKchr1:1696667chr8:145245687ENST00000378625-214326_33359.666666666666664592.0Compositional biasNote=Poly-Ala
HgeneNADKchr1:1696667chr8:145245687ENST00000378625-214437_44559.666666666666664592.0Compositional biasNote=Poly-Glu
TgeneMROH1chr1:1696667chr8:145245687ENST00000326134442159_198187.333333333333341642.0RepeatNote=HEAT 2
TgeneMROH1chr1:1696667chr8:145245687ENST000003261344423_41187.333333333333341642.0RepeatNote=HEAT 1
TgeneMROH1chr1:1696667chr8:145245687ENST00000398656543159_198187.333333333333341642.0RepeatNote=HEAT 2
TgeneMROH1chr1:1696667chr8:145245687ENST000003986565433_41187.333333333333341642.0RepeatNote=HEAT 1
TgeneMROH1chr1:1696667chr8:145245687ENST00000423230512159_198187.33333333333334423.0RepeatNote=HEAT 2
TgeneMROH1chr1:1696667chr8:145245687ENST000004232305123_41187.33333333333334423.0RepeatNote=HEAT 1
TgeneMROH1chr1:1696667chr8:145245687ENST00000528919543159_198187.333333333333341642.0RepeatNote=HEAT 2
TgeneMROH1chr1:1696667chr8:145245687ENST000005289195433_41187.333333333333341642.0RepeatNote=HEAT 1


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Fusion Gene Sequence for NADK-MROH1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000378625_ENST00000423230_TCGA-04-1361-01A_NADK_chr1_1696667_-_MROH1_chr8_145245687_length(transcript)=1437nt_BP=384nt
AAATCCCCCAAGTTCTCATGATCCTTGCTTCCCTTTCCAGTCACCCTTGGTGCCCTGTACTTCACTGTGGTCCTGAACTGAAGAGCTGTG
TTTTTCAGGAAGACTTGGCCAGGCCGTGTTCCGTGTCTCTGGATTCAAGTCCCAGGAGTCCTGACCAGAGAGCAGGCATCAGTGTTTTTC
TGACCGAAGTTCTCATTTCCTGACAATGGAAATGGAACAAGAAAAAATGACCATGAATAAGGAATTGAGTCCAGACGCGGCTGCTTACTG
CTGCTCGGCCTGCCACGGCGATGAGACCTGGAGTTACAACCACCCCATCCGGGGCCGGGCCAAGTCTCGCAGCCTGTCTGCCTCGCCCGC
CCTGGGGAGCACCAAGGAGTTCAGCTCTGCAGCGCTTCAGCGAGGGTGCCCTGGAGTACCTAGCCAACCTGGACCGAGCCCCAGACCCCA
CGGTCAGGAAGGACGCCTTTGCCACCGACATCTTCAGCGCCTACGATGTTCTCTTCCATCAGTGGCTGCAGAGTCGAGAAGCCAAGCTCC
GTCTTGCCGTGGTGGAGGCTCTGGGGCCTATGAGCCATCTGCTGCCCAGTGAGAGGCTGGAAGAGCAGCTGCCCAAGCTCCTCCCTGGGA
TTCTCGCCCTCTACAAGAAGCACGCAGAGACCTTCTACTTGTCCAAGAGCCTGGGCCAGATCCTCGAGGCAGCTGTGAGTGTGGGCAGCC
GCACACTGGAGACCCAGCTGGATGCCCTCTTGGCTGCACTGCACTCCCAGATCTGTGTGCCTGTGGAGTCCTCAAGCCCCCTGGTGATGA
GTAACCAGAAGGAGGTGCTGCGCTGCTTCACTGTGCTGGCCTGCAGCTCGCCTGACCGCCTACTGGCCTTCCTGCTGCCCAGGCTGGACA
CCAGCAATGAGAGGACCCGCGTGGGCACCCTGCAGGTGGTCAGACATGTCATCAACTCAGCTGGCAGCACTAACACCAGAATAACACTGA
TGTTGCCATCAGCAGTCACACGACTGAAACATGAGGACTGCCCTGCACGTGCTGCTCCGCAGCCTGCTGATCTAACGGCCGCGCCCGCGT
CTGTTGCTTGAGTCACCACGGCTGTTACATCCCGTGCTCTCCCTTCTCTGCCTTCTTGGTGTTGGTTCTGCGGGCGACTGCCCATGTGGC
CCTCAGCCCCATCCTCTGTTCATGGCTCTCTGCCACTCTTGTTGTCCAAAGCTCTTTCTCTGTAGGTTCCGTGGGAAGAGCTCATGGGAA
CATGATCTTCGACCTCATGCTTGCTGATCATAGTTTATTGTGCCTTTTATCGTTGATGGTTTTGCTGGTTACAGGATTCTTGGCTGACAT

>In-frame_ENST00000378625_ENST00000423230_TCGA-04-1361-01A_NADK_chr1_1696667_-_MROH1_chr8_145245687_length(amino acids)=276AA_start in transcript=260_stop in transcript=1090
MLTAARPATAMRPGVTTTPSGAGPSLAACLPRPPWGAPRSSALQRFSEGALEYLANLDRAPDPTVRKDAFATDIFSAYDVLFHQWLQSRE
AKLRLAVVEALGPMSHLLPSERLEEQLPKLLPGILALYKKHAETFYLSKSLGQILEAAVSVGSRTLETQLDALLAALHSQICVPVESSSP
LVMSNQKEVLRCFTVLACSSPDRLLAFLLPRLDTSNERTRVGTLQVVRHVINSAGSTNTRITLMLPSAVTRLKHEDCPARAAPQPADLTA

--------------------------------------------------------------
>In-frame_ENST00000378625_ENST00000398656_TCGA-04-1361-01A_NADK_chr1_1696667_-_MROH1_chr8_145245687_length(transcript)=4748nt_BP=384nt
AAATCCCCCAAGTTCTCATGATCCTTGCTTCCCTTTCCAGTCACCCTTGGTGCCCTGTACTTCACTGTGGTCCTGAACTGAAGAGCTGTG
TTTTTCAGGAAGACTTGGCCAGGCCGTGTTCCGTGTCTCTGGATTCAAGTCCCAGGAGTCCTGACCAGAGAGCAGGCATCAGTGTTTTTC
TGACCGAAGTTCTCATTTCCTGACAATGGAAATGGAACAAGAAAAAATGACCATGAATAAGGAATTGAGTCCAGACGCGGCTGCTTACTG
CTGCTCGGCCTGCCACGGCGATGAGACCTGGAGTTACAACCACCCCATCCGGGGCCGGGCCAAGTCTCGCAGCCTGTCTGCCTCGCCCGC
CCTGGGGAGCACCAAGGAGTTCAGCTCTGCAGCGCTTCAGCGAGGGTGCCCTGGAGTACCTAGCCAACCTGGACCGAGCCCCAGACCCCA
CGGTCAGGAAGGACGCCTTTGCCACCGACATCTTCAGCGCCTACGATGTTCTCTTCCATCAGTGGCTGCAGAGTCGAGAAGCCAAGCTCC
GTCTTGCCGTGGTGGAGGCTCTGGGGCCTATGAGCCATCTGCTGCCCAGTGAGAGGCTGGAAGAGCAGCTGCCCAAGCTCCTCCCTGGGA
TTCTCGCCCTCTACAAGAAGCACGCAGAGACCTTCTACTTGTCCAAGAGCCTGGGCCAGATCCTCGAGGCAGCTGTGAGTGTGGGCAGCC
GCACACTGGAGACCCAGCTGGATGCCCTCTTGGCTGCACTGCACTCCCAGATCTGTGTGCCTGTGGAGTCCTCAAGCCCCCTGGTGATGA
GTAACCAGAAGGAGGTGCTGCGCTGCTTCACTGTGCTGGCCTGCAGCTCGCCTGACCGCCTACTGGCCTTCCTGCTGCCCAGGCTGGACA
CCAGCAATGAGAGGACCCGCGTGGGCACCCTGCAGGTGGTCAGACATGTCATCAACTCAGCTGCTGCTCAGATGGAAGATAAAAAGCCCT
TTATCCTGTCTTCCATGAGGCTTCCTCTCCTGGACACCAACAGCAAGGTGAAGCGGGCAGTGGTGCAGGTGATTAGCGCCATGGCCCACC
ACGGCTACCTGGAGCAGCCTGGAGGTGAGGCGATGATCGAGTACATCGTGCAGCAGTGCGCGCTGCCCCCCGAGCAGGAGCCTGAGAAGC
CAGGCCCCGGCAGCAAGGACCCCAAGGCCGACAGCGTGCGGGCCATCAGCGTGCGCACCCTCTACCTGGTCAGCACCACCGTGGACAGGA
TGAGTCACGTCCTCTGGCCATACCTGCTCCAGTTCCTCACCCCTGTGCGCTTCACTGGGGCCCTGACTCCGCTCTGCAGGAGCCTCGTGC
ATCTGGCGCAGAAGAGGCAGGAGGCCGGGGCCGACGCCTTCCTCATCCAGTACGACGCCCATGCGAGCCTCCCGTCTCCCTATGCTGTAA
CCGGAAGACTGTTGGTTGTGTCTTCCAGCCCCTACCTAGGGGACGGACGTGGGGCAGCGGCGCTGCGCCTCCTCAGTGTTCTGCACCCAA
ACATTCACCCTTTGCTGGGTCAGCATTGGGAAACGACTGTCCCGCTGCTGCTGGGGTACCTGGATGAGCACACAGAAGAGACCCTGCCAC
AGGAGGAGTGGGAGGAGAAGCTGTTGATGTTCCTGCGAGACACCCTGGCCATCATTTCTGACAACGCGTGGATCTGCCAGCTGAGCCTGG
AGCTGTGCAGGCAGCTGCCCTGCTACGATGAGGCACCCCAGGAGAAGAACTTCCTGTACAAATGCATAGGCACCACCCTGGGTGCTGCTT
CAAGTAAGGAGGTGGTGAGGAAGCACCTTCAAGAGCTGCTGGAGACGGCCAGATACCAGGAGGAGGCAGAACGCGAGGGCCTCGCCTGCT
GCTTCGGGATCTGTGCCATCTCCCACCTCGAGGACACGCTGGCCCAGCTGGAGGACTTCGTGAGGTCAGAGGTCTTCAGAAAATCCATTG
GCATTCTCAACATTTTTAAGGATCGAAGTGAGAACGAAGTGGAGAAGGTGAAGAGTGCTCTGATCCTGTGCTATGGGCACGTGGCGGCCC
GGGCCCCCCGGGAGCTGGTGCTGGCCAAGGTAGAGTCAGACATCCTCCGGAACATCTGCCAGCACTTCAGCACCAAGGTTCTAGGAATAA
AGGTAGAAACCAAGGACCCAGCCCTGAAGCTGTGCCTTGTCCAGAGTGTGTGCATGGTCAGCCGCGCCATCTGCAGCAGCACCCAGGCTG
GCTCCTTCCACTTCACCCGGAAAGCAGAGCTGGTGGCACAGATGATGGAGTTCATCAGGGCAGAGCCCCCGGACTCCTTGAGGACACCTA
TTCGGAAGAAAGCCATGCTCACCTGCACTTACTTGGTCTCCGTGGAGCCAGCGCTGGACGAGCAGGCCCGGGCGGATGTGATCCATGGCT
GCCTGCACAGCATCATGGCCCTGCTGCCTGAGCCCAAGGAGGAGGACGGAGGCTGCCAGAAGTCCCTGTATCTGGAGACACTGCACGCCC
TTGAGGATCTGCTGACGAGCCTCCTGCAGCGGAACATGACCCCCCAAGGCCTGCAGATCATGATTGAGCACCTGAGCCCATGGATCAAGT
CCCCAAGAGGTCACGAGCGGGCGCGGGCCCTGGGCCTGAGCGCCCTCCTGCTGCGCTACTTCCTGGAGCACCTGCGTGTCAGCGCCCTGG
TGCCCTTCCACAACCTGGGCCTTCTCATCGGCCTCTTCTCCCCACGGTGTGCGGACCTGTGGCCTGCCACCCGCCAGGAGGCCGTGGACT
GTGTCTACTCCCTGCTGTACCTCCAGCTCGGCTATGAGGGCTTCTCCCGGGACTACCGCGATGACGTGGCGGAGCGGCTCCTCAGCCTCA
AGGACGGCCTCGTGCACCCTGACCCCGCCATTCTCTTCCACACCTGCCACAGTGTAGGCCAGATTATTGCCAAGCGCCTCCCCCCAGACC
AGCTCATCAGCCTCTTGCTAACCATGTTTGAGGCCCTGGGAGACCCCGAAAAGAACTGCTCCCGAGCAGCTACCGTCATGATCAACTGCC
TGCTGCAGGAGCGGGGCGGTGTGCTCCAGGAGAAGGTGCCCGAGATCGTGAGCGTCCTGCGCTCCAAGCTTCAGGAGGCCCAGGGAGAGC
ACGTCCTGCCGGCCGCCCAGCACAGCGTGTACCTCCTGGCCACCCAGCACTGCGCAGCCGTGGTGTCCAGCCTCCTGGGCAGCCCCTTGC
CCTTGGACAGCCACACCTGCATGCTGTGGCGGGCGCTGGCGGTGGAGCCTCGCCTAGCTGCCCAGGTCCTGGGGCTGCTGCTGGAGAAGA
TGAGTAGGGACGTCCCTTTCAAGGAGAGCCGGGCCTTCCTGCTGGGCCGCACCCCAGACCGCGTGGCCACGCTGCTGCCTCTCTCGGCTA
CCTGTGCACTGTTTGAGGTCATGTCCACGCCTGCAGCGGGGCCCGCGGTGCTCGAGCTCTACCCCCAGCTGTTTGTGGTGCTTCTGCTGC
GCGTCAGCTGCACCGTGGGTGTCCAGCTGCCCCGGAACCTGCAGGCCCAGGAAAGGAGGGGTGCCAGTCCAGCCCTAGCCACCAGGAACC
TGGAACCCTGCAGCTCTGCAGTGGACACCCTGCGGTCCATGCTACTCCGCAGCGGCAGCGAGGATGTGGTACAGCGCATGGACCTGGAGG
GAGGCTGGGAACTGCTCAGGACCTCGGCGGGGCATGAGGAGGGGGCCACCAGGTTGGCCAGGGCCATGGCTGAGCACGCAGGGCCCCGAC
TCCCCCTGGTGCTGAAGACGCTGGCATGCACACACAGCAGTGCGTATGAGAACCAGAGGGTGACCACCACCGCCTTCCTGGCCGAGCTGC
TGAACAGCAACGTGGCCAACGACCTCATGCTCTTGGACTCGCTGCTGGAGAGCCTGGCGGCTCGCCAGAAGGACACATGCGCCAGCGTGC
GGAGGCTGGTGCTCCGCGGCCTGGCCAACCTGGCCTCCGGCTGCCCTGACAAGGTGCGAACCCACGGCCCCCAGCTCCTCACAGCCATGA
TTGGCGGGCTGGACGACGGGGACAACCCTCACAGCCCAGTGGCCCTGGAGGCCATGCTGGGCCTTGCGAGGCTGGTGCACCTGGTGGAGT
CCTGGGACCTGCGCTCAGGGCTGCTGCACGTGGCCATCCGCATCCGGCCTTTCTTCGACAGTGAGAAGATGGAGTTCCGGACGGCATCTA
TCCGCCTCTTTGGGCACCTTAACAAGGTCTGCCACGGAGACTGTGAGGACGTCTTCCTGGACCAGGTGGTGGGCGGGCTGGCGCCCCTGC
TGCTGCACCTGCAGGACCCTCAGGCCACCGTGGCCAGCGCCTGCAGGTTTGCCCTGCGCATGTGTGGCCCCAATCTGGCATGTGAGGAGC
TCTCAGCTGCTTTCCAGAAACACCTGCAGGAGGGCCGAGCCCTGCACTTCGGGGAGTTCCTCAACACCACCTGCAAGCACCTGATGCACC
ATTTCCCAGACCTGCTGGGCCGTCTCCTGACCACCTGCCTGTTCTACTTCAAGAGCAGCTGGGAGAACGTCCGAGCTGCTGCACCCCTGT
TCACCGGGTTCCTGGTGCTGCACTCGGAGCCCAGGCAGCAGCCGCAGGTGGACCTGGACCAGCTCATTGCGGCGCTCCAGATCCTGCTGA

>In-frame_ENST00000378625_ENST00000398656_TCGA-04-1361-01A_NADK_chr1_1696667_-_MROH1_chr8_145245687_length(amino acids)=1496AA_start in transcript=260_stop in transcript=4747
MLTAARPATAMRPGVTTTPSGAGPSLAACLPRPPWGAPRSSALQRFSEGALEYLANLDRAPDPTVRKDAFATDIFSAYDVLFHQWLQSRE
AKLRLAVVEALGPMSHLLPSERLEEQLPKLLPGILALYKKHAETFYLSKSLGQILEAAVSVGSRTLETQLDALLAALHSQICVPVESSSP
LVMSNQKEVLRCFTVLACSSPDRLLAFLLPRLDTSNERTRVGTLQVVRHVINSAAAQMEDKKPFILSSMRLPLLDTNSKVKRAVVQVISA
MAHHGYLEQPGGEAMIEYIVQQCALPPEQEPEKPGPGSKDPKADSVRAISVRTLYLVSTTVDRMSHVLWPYLLQFLTPVRFTGALTPLCR
SLVHLAQKRQEAGADAFLIQYDAHASLPSPYAVTGRLLVVSSSPYLGDGRGAAALRLLSVLHPNIHPLLGQHWETTVPLLLGYLDEHTEE
TLPQEEWEEKLLMFLRDTLAIISDNAWICQLSLELCRQLPCYDEAPQEKNFLYKCIGTTLGAASSKEVVRKHLQELLETARYQEEAEREG
LACCFGICAISHLEDTLAQLEDFVRSEVFRKSIGILNIFKDRSENEVEKVKSALILCYGHVAARAPRELVLAKVESDILRNICQHFSTKV
LGIKVETKDPALKLCLVQSVCMVSRAICSSTQAGSFHFTRKAELVAQMMEFIRAEPPDSLRTPIRKKAMLTCTYLVSVEPALDEQARADV
IHGCLHSIMALLPEPKEEDGGCQKSLYLETLHALEDLLTSLLQRNMTPQGLQIMIEHLSPWIKSPRGHERARALGLSALLLRYFLEHLRV
SALVPFHNLGLLIGLFSPRCADLWPATRQEAVDCVYSLLYLQLGYEGFSRDYRDDVAERLLSLKDGLVHPDPAILFHTCHSVGQIIAKRL
PPDQLISLLLTMFEALGDPEKNCSRAATVMINCLLQERGGVLQEKVPEIVSVLRSKLQEAQGEHVLPAAQHSVYLLATQHCAAVVSSLLG
SPLPLDSHTCMLWRALAVEPRLAAQVLGLLLEKMSRDVPFKESRAFLLGRTPDRVATLLPLSATCALFEVMSTPAAGPAVLELYPQLFVV
LLLRVSCTVGVQLPRNLQAQERRGASPALATRNLEPCSSAVDTLRSMLLRSGSEDVVQRMDLEGGWELLRTSAGHEEGATRLARAMAEHA
GPRLPLVLKTLACTHSSAYENQRVTTTAFLAELLNSNVANDLMLLDSLLESLAARQKDTCASVRRLVLRGLANLASGCPDKVRTHGPQLL
TAMIGGLDDGDNPHSPVALEAMLGLARLVHLVESWDLRSGLLHVAIRIRPFFDSEKMEFRTASIRLFGHLNKVCHGDCEDVFLDQVVGGL
APLLLHLQDPQATVASACRFALRMCGPNLACEELSAAFQKHLQEGRALHFGEFLNTTCKHLMHHFPDLLGRLLTTCLFYFKSSWENVRAA

--------------------------------------------------------------
>In-frame_ENST00000378625_ENST00000534366_TCGA-04-1361-01A_NADK_chr1_1696667_-_MROH1_chr8_145245687_length(transcript)=4790nt_BP=384nt
AAATCCCCCAAGTTCTCATGATCCTTGCTTCCCTTTCCAGTCACCCTTGGTGCCCTGTACTTCACTGTGGTCCTGAACTGAAGAGCTGTG
TTTTTCAGGAAGACTTGGCCAGGCCGTGTTCCGTGTCTCTGGATTCAAGTCCCAGGAGTCCTGACCAGAGAGCAGGCATCAGTGTTTTTC
TGACCGAAGTTCTCATTTCCTGACAATGGAAATGGAACAAGAAAAAATGACCATGAATAAGGAATTGAGTCCAGACGCGGCTGCTTACTG
CTGCTCGGCCTGCCACGGCGATGAGACCTGGAGTTACAACCACCCCATCCGGGGCCGGGCCAAGTCTCGCAGCCTGTCTGCCTCGCCCGC
CCTGGGGAGCACCAAGGAGTTCAGCTCTGCAGCGCTTCAGCGAGGGTGCCCTGGAGTACCTAGCCAACCTGGACCGAGCCCCAGACCCCA
CGGTCAGGAAGGACGCCTTTGCCACCGACATCTTCAGCGCCTACGATGTTCTCTTCCATCAGTGGCTGCAGAGTCGAGAAGCCAAGCTCC
GTCTTGCCGTGGTGGAGGCTCTGGGGCCTATGAGCCATCTGCTGCCCAGTGAGAGGCTGGAAGAGCAGCTGCCCAAGCTCCTCCCTGGGA
TTCTCGCCCTCTACAAGAAGCACGCAGAGACCTTCTACTTGTCCAAGAGCCTGGGCCAGATCCTCGAGGCAGCTGTGAGTGTGGGCAGCC
GCACACTGGAGACCCAGCTGGATGCCCTCTTGGCTGCACTGCACTCCCAGATCTGTGTGCCTGTGGAGTCCTCAAGCCCCCTGGTGATGA
GTAACCAGAAGGAGGTGCTGCGCTGCTTCACTGTGCTGGCCTGCAGCTCGCCTGACCGCCTACTGGCCTTCCTGCTGCCCAGGCTGGACA
CCAGCAATGAGAGGACCCGCGTGGGCACCCTGCAGGTGGTCAGACATGTCATCAACTCAGCTGCTGCTCAGATGGAAGATAAAAAGCCCT
TTATCCTGTCTTCCATGAGGCTTCCTCTCCTGGACACCAACAGCAAGGTGAAGCGGGCAGTGGTGCAGGTGATTAGCGCCATGGCCCACC
ACGGCTACCTGGAGCAGCCTGGAGGTGAGGCGATGATCGAGTACATCGTGCAGCAGTGCGCGCTGCCCCCCGAGCAGGAGCCTGAGAAGC
CAGGCCCCGGCAGCAAGGACCCCAAGGCCGACAGCGTGCGGGCCATCAGCGTGCGCACCCTCTACCTGGTCAGCACCACCGTGGACAGGA
TGAGTCACGTCCTCTGGCCATACCTGCTCCAGTTCCTCACCCCTGTGCGCTTCACTGGGGCCCTGACTCCGCTCTGCAGGAGCCTCGTGC
ATCTGGCGCAGAAGAGGCAGGAGGCCGGGGCCGACGCCTTCCTCATCCAGTACGACGCCCATGCGAGCCTCCCGTCTCCCTATGCTGTAA
CCGGAAGACTGTTGGTTGTGTCTTCCAGCCCCTACCTAGGGGACGGACGTGGGGCAGCGGCGCTGCGCCTCCTCAGTGTTCTGCACCCAA
ACATTCACCCTTTGCTGGGTCAGCATTGGGAAACGACTGTCCCGCTGCTGCTGGGGTACCTGGATGAGCACACAGAAGAGACCCTGCCAC
AGGAGGAGTGGGAGGAGAAGCTGTTGATGTTCCTGCGAGACACCCTGGCCATCATTTCTGACAACGCGTGGATCTGCCAGCTGAGCCTGG
AGCTGTGCAGGCAGCTGCCCTGCTACGATGAGGCACCCCAGGAGAAGAACTTCCTGTACAAATGCATAGGCACCACCCTGGGTGCTGCTT
CAAGTAAGGAGGTGGTGAGGAAGCACCTTCAAGAGCTGCTGGAGACGGCCAGATACCAGGAGGAGGCAGAACGCGAGGGCCTCGCCTGCT
GCTTCGGGATCTGTGCCATCTCCCACCTCGAGGACACGCTGGCCCAGCTGGAGGACTTCGTGAGGTCAGAGGTCTTCAGAAAATCCATTG
GCATTCTCAACATTTTTAAGGATCGAAGTGAGAACGAAGTGGAGAAGGTGAAGAGTGCTCTGATCCTGTGCTATGGGCACGTGGCGGCCC
GGGCCCCCCGGGAGCTGGTGCTGGCCAAGGTAGAGTCAGACATCCTCCGGAACATCTGCCAGCACTTCAGCACCAAGGACCCAGCCCTGA
AGCTGTGCCTTGTCCAGAGTGTGTGCATGGTCAGCCGCGCCATCTGCAGCAGCACCCAGGCTGGCTCCTTCCACTTCACCCGGAAAGCAG
AGCTGGTGGCACAGATGATGGAGTTCATCAGGGCAGAGCCCCCGGACTCCTTGAGGACACCTATTCGGAAGAAAGCCATGCTCACCTGCA
CTTACTTGGTCTCCGTGGAGCCAGCGCTGGACGAGCAGGCCCGGGCGGATGTGATCCATGGCTGCCTGCACAGCATCATGGCCCTGCTGC
CTGAGCCCAAGGAGGAGGACGGAGGCTGCCAGAAGTCCCTGTATCTGGAGACACTGCACGCCCTTGAGGATCTGCTGACGAGCCTCCTGC
AGCGGAACATGACCCCCCAAGGCCTGCAGATCATGATTGAGCACCTGAGCCCATGGATCAAGTCCCCAAGAGGTCACGAGCGGGCGCGGG
CCCTGGGCCTGAGCGCCCTCCTGCTGCGCTACTTCCTGGAGCACCTGCGTGTCAGCGCCCTGGTGCCCTTCCACAACCTGGGCCTTCTCA
TCGGCCTCTTCTCCCCACGGTGTGCGGACCTGTGGCCTGCCACCCGCCAGGAGGCCGTGGACTGTGTCTACTCCCTGCTGTACCTCCAGC
TCGGCTATGAGGGCTTCTCCCGGGACTACCGCGATGACGTGGCGGAGCGGCTCCTCAGCCTCAAGGACGGCCTCGTGCACCCTGACCCCG
CCATTCTCTTCCACACCTGCCACAGTGTAGGCCAGATTATTGCCAAGCGCCTCCCCCCAGACCAGCTCATCAGCCTCTTGCTAACCATGT
TTGAGGCCCTGGGAGACCCCGAAAAGAACTGCTCCCGAGCAGCTACCGTCATGATCAACTGCCTGCTGCAGGAGCGGGGCGGTGTGCTCC
AGGAGAAGGTGCCCGAGATCGTGAGCGTCCTGCGCTCCAAGCTTCAGGAGGCCCAGGGAGAGCACGTCCTGCCGGCCGCCCAGCACAGCG
TGTACCTCCTGGCCACCCAGCACTGCGCAGCCGTGGTGTCCAGCCTCCTGGGCAGCCCCTTGCCCTTGGACAGCCACACCTGCATGCTGT
GGCGGGCGCTGGCGGTGGAGCCTCGCCTAGCTGCCCAGGTCCTGGGGCTGCTGCTGGAGAAGATGAGTAGGGACGTCCCTTTCAAGGAGA
GCCGGGCCTTCCTGCTGGGCCGCACCCCAGACCGCGTGGCCACGCTGCTGCCTCTCTCGGCTACCTGTGCACTGTTTGAGGTCATGTCCA
CGCCTGCAGCGGGGCCCGCGGTGCTCGAGCTCTACCCCCAGCTGTTTGTGGTGCTTCTGCTGCGCGTCAGCTGCACCGTGGGTGTCCAGC
TGCCCCGGAACCTGCAGGCCCAGGAAAGGAGGGGTGCCAGTCCAGCCCTAGCCACCAGGAACCTGGAACCCTGCAGCTCTGCAGTGGACA
CCCTGCGGTCCATGCTACTCCGCAGCGGCAGCGAGGATGTGGTACAGCGCATGGACCTGGAGGGAGGCTGGGAACTGCTCAGGACCTCGG
CGGGGCATGAGGAGGGGGCCACCAGGTTGGCCAGGGCCATGGCTGAGCACGCAGGGCCCCGACTCCCCCTGGTGCTGAAGACGCTGGCAT
GCACACACAGCAGTGCGTATGAGAACCAGAGGGTGACCACCACCGCCTTCCTGGCCGAGCTGCTGAACAGCAACGTGGCCAACGACCTCA
TGCTCTTGGACTCGCTGCTGGAGAGCCTGGCGGCTCGCCAGAAGGACACATGCGCCAGCGTGCGGAGGCTGGTGCTCCGCGGCCTGGCCA
ACCTGGCCTCCGGCTGCCCTGACAAGGTGCGAACCCACGGCCCCCAGCTCCTCACAGCCATGATTGGCGGGCTGGACGACGGGGACAACC
CTCACAGCCCAGTGGCCCTGGAGGCCATGCTGGGCCTTGCGAGGCTGGTGCACCTGGTGGAGTCCTGGGACCTGCGCTCAGGGCTGCTGC
ACGTGGCCATCCGCATCCGGCCTTTCTTCGACAGTGAGAAGATGGAGTTCCGGACGGCATCTATCCGCCTCTTTGGGCACCTTAACAAGG
TCTGCCACGGAGACTGTGAGGACGTCTTCCTGGACCAGGTGGTGGGCGGGCTGGCGCCCCTGCTGCTGCACCTGCAGGACCCTCAGGCCA
CCGTGGCCAGCGCCTGCAGGTTTGCCCTGCGCATGTGTGGCCCCAATCTGGCATGTGAGGAGCTCTCAGCTGCTTTCCAGAAACACCTGC
AGGAGGGCCGAGCCCTGCACTTCGGGGAGTTCCTCAACACCACCTGCAAGCACCTGATGCACCATTTCCCAGACCTGCTGGGCCGTCTCC
TGACCACCTGCCTGTTCTACTTCAAGAGCAGCTGGGAGAACGTCCGAGCTGCTGCACCCCTGTTCACCGGGTTCCTGGTGCTGCACTCGG
AGCCCAGGCAGCAGCCGCAGGTGGACCTGGACCAGCTCATTGCGGCGCTCCAGATCCTGCTGAAGGACCCGGCCCCCGAGGTGCGGACGA
GGGCTGCTGAGGCCCTGGGCCGCCTGGTGAAGCTCGCCTAAGGCTCCGGCCAGCACCCCCAGCGAGGAGTATGCACCCAGACCTGTGCCT

>In-frame_ENST00000378625_ENST00000534366_TCGA-04-1361-01A_NADK_chr1_1696667_-_MROH1_chr8_145245687_length(amino acids)=1486AA_start in transcript=260_stop in transcript=4720
MLTAARPATAMRPGVTTTPSGAGPSLAACLPRPPWGAPRSSALQRFSEGALEYLANLDRAPDPTVRKDAFATDIFSAYDVLFHQWLQSRE
AKLRLAVVEALGPMSHLLPSERLEEQLPKLLPGILALYKKHAETFYLSKSLGQILEAAVSVGSRTLETQLDALLAALHSQICVPVESSSP
LVMSNQKEVLRCFTVLACSSPDRLLAFLLPRLDTSNERTRVGTLQVVRHVINSAAAQMEDKKPFILSSMRLPLLDTNSKVKRAVVQVISA
MAHHGYLEQPGGEAMIEYIVQQCALPPEQEPEKPGPGSKDPKADSVRAISVRTLYLVSTTVDRMSHVLWPYLLQFLTPVRFTGALTPLCR
SLVHLAQKRQEAGADAFLIQYDAHASLPSPYAVTGRLLVVSSSPYLGDGRGAAALRLLSVLHPNIHPLLGQHWETTVPLLLGYLDEHTEE
TLPQEEWEEKLLMFLRDTLAIISDNAWICQLSLELCRQLPCYDEAPQEKNFLYKCIGTTLGAASSKEVVRKHLQELLETARYQEEAEREG
LACCFGICAISHLEDTLAQLEDFVRSEVFRKSIGILNIFKDRSENEVEKVKSALILCYGHVAARAPRELVLAKVESDILRNICQHFSTKD
PALKLCLVQSVCMVSRAICSSTQAGSFHFTRKAELVAQMMEFIRAEPPDSLRTPIRKKAMLTCTYLVSVEPALDEQARADVIHGCLHSIM
ALLPEPKEEDGGCQKSLYLETLHALEDLLTSLLQRNMTPQGLQIMIEHLSPWIKSPRGHERARALGLSALLLRYFLEHLRVSALVPFHNL
GLLIGLFSPRCADLWPATRQEAVDCVYSLLYLQLGYEGFSRDYRDDVAERLLSLKDGLVHPDPAILFHTCHSVGQIIAKRLPPDQLISLL
LTMFEALGDPEKNCSRAATVMINCLLQERGGVLQEKVPEIVSVLRSKLQEAQGEHVLPAAQHSVYLLATQHCAAVVSSLLGSPLPLDSHT
CMLWRALAVEPRLAAQVLGLLLEKMSRDVPFKESRAFLLGRTPDRVATLLPLSATCALFEVMSTPAAGPAVLELYPQLFVVLLLRVSCTV
GVQLPRNLQAQERRGASPALATRNLEPCSSAVDTLRSMLLRSGSEDVVQRMDLEGGWELLRTSAGHEEGATRLARAMAEHAGPRLPLVLK
TLACTHSSAYENQRVTTTAFLAELLNSNVANDLMLLDSLLESLAARQKDTCASVRRLVLRGLANLASGCPDKVRTHGPQLLTAMIGGLDD
GDNPHSPVALEAMLGLARLVHLVESWDLRSGLLHVAIRIRPFFDSEKMEFRTASIRLFGHLNKVCHGDCEDVFLDQVVGGLAPLLLHLQD
PQATVASACRFALRMCGPNLACEELSAAFQKHLQEGRALHFGEFLNTTCKHLMHHFPDLLGRLLTTCLFYFKSSWENVRAAAPLFTGFLV

--------------------------------------------------------------
>In-frame_ENST00000378625_ENST00000528919_TCGA-04-1361-01A_NADK_chr1_1696667_-_MROH1_chr8_145245687_length(transcript)=4935nt_BP=384nt
AAATCCCCCAAGTTCTCATGATCCTTGCTTCCCTTTCCAGTCACCCTTGGTGCCCTGTACTTCACTGTGGTCCTGAACTGAAGAGCTGTG
TTTTTCAGGAAGACTTGGCCAGGCCGTGTTCCGTGTCTCTGGATTCAAGTCCCAGGAGTCCTGACCAGAGAGCAGGCATCAGTGTTTTTC
TGACCGAAGTTCTCATTTCCTGACAATGGAAATGGAACAAGAAAAAATGACCATGAATAAGGAATTGAGTCCAGACGCGGCTGCTTACTG
CTGCTCGGCCTGCCACGGCGATGAGACCTGGAGTTACAACCACCCCATCCGGGGCCGGGCCAAGTCTCGCAGCCTGTCTGCCTCGCCCGC
CCTGGGGAGCACCAAGGAGTTCAGCTCTGCAGCGCTTCAGCGAGGGTGCCCTGGAGTACCTAGCCAACCTGGACCGAGCCCCAGACCCCA
CGGTCAGGAAGGACGCCTTTGCCACCGACATCTTCAGCGCCTACGATGTTCTCTTCCATCAGTGGCTGCAGAGTCGAGAAGCCAAGCTCC
GTCTTGCCGTGGTGGAGGCTCTGGGGCCTATGAGCCATCTGCTGCCCAGTGAGAGGCTGGAAGAGCAGCTGCCCAAGCTCCTCCCTGGGA
TTCTCGCCCTCTACAAGAAGCACGCAGAGACCTTCTACTTGTCCAAGAGCCTGGGCCAGATCCTCGAGGCAGCTGTGAGTGTGGGCAGCC
GCACACTGGAGACCCAGCTGGATGCCCTCTTGGCTGCACTGCACTCCCAGATCTGTGTGCCTGTGGAGTCCTCAAGCCCCCTGGTGATGA
GTAACCAGAAGGAGGTGCTGCGCTGCTTCACTGTGCTGGCCTGCAGCTCGCCTGACCGCCTACTGGCCTTCCTGCTGCCCAGGCTGGACA
CCAGCAATGAGAGGACCCGCGTGGGCACCCTGCAGGTGGTCAGACATGTCATCAACTCAGCTGCTGCTCAGATGGAAGATAAAAAGCCCT
TTATCCTGTCTTCCATGAGGCTTCCTCTCCTGGACACCAACAGCAAGGTGAAGCGGGCAGTGGTGCAGGTGATTAGCGCCATGGCCCACC
ACGGCTACCTGGAGCAGCCTGGAGGTGAGGCGATGATCGAGTACATCGTGCAGCAGTGCGCGCTGCCCCCCGAGCAGGAGCCTGAGAAGC
CAGGCCCCGGCAGCAAGGACCCCAAGGCCGACAGCGTGCGGGCCATCAGCGTGCGCACCCTCTACCTGGTCAGCACCACCGTGGACAGGA
TGAGTCACGTCCTCTGGCCATACCTGCTCCAGTTCCTCACCCCTGTGCGCTTCACTGGGGCCCTGACTCCGCTCTGCAGGAGCCTCGTGC
ATCTGGCGCAGAAGAGGCAGGAGGCCGGGGCCGACGCCTTCCTCATCCAGTACGACGCCCATGCGAGCCTCCCGTCTCCCTATGCTGTAA
CCGGAAGACTGTTGGTTGTGTCTTCCAGCCCCTACCTAGGGGACGGACGTGGGGCAGCGGCGCTGCGCCTCCTCAGTGTTCTGCACCCAA
ACATTCACCCTTTGCTGGGTCAGCATTGGGAAACGACTGTCCCGCTGCTGCTGGGGTACCTGGATGAGCACACAGAAGAGACCCTGCCAC
AGGAGGAGTGGGAGGAGAAGCTGTTGATGTTCCTGCGAGACACCCTGGCCATCATTTCTGACAACGCGTGGATCTGCCAGCTGAGCCTGG
AGCTGTGCAGGCAGCTGCCCTGCTACGATGAGGCACCCCAGGAGAAGAACTTCCTGTACAAATGCATAGGCACCACCCTGGGTGCTGCTT
CAAGTAAGGAGGTGGTGAGGAAGCACCTTCAAGAGCTGCTGGAGACGGCCAGATACCAGGAGGAGGCAGAACGCGAGGGCCTCGCCTGCT
GCTTCGGGATCTGTGCCATCTCCCACCTCGAGGACACGCTGGCCCAGCTGGAGGACTTCGTGAGGTCAGAGGTCTTCAGAAAATCCATTG
GCATTCTCAACATTTTTAAGGATCGAAGTGAGAACGAAGTGGAGAAGGTGAAGAGTGCTCTGATCCTGTGCTATGGGCACGTGGCGGCCC
GGGCCCCCCGGGAGCTGGTGCTGGCCAAGGTAGAGTCAGACATCCTCCGGAACATCTGCCAGCACTTCAGCACCAAGGTTCTAGGAATAA
AGGTAGAAACCAAGGACCCAGCCCTGAAGCTGTGCCTTGTCCAGAGTGTGTGCATGGTCAGCCGCGCCATCTGCAGCAGCACCCAGGCTG
GCTCCTTCCACTTCACCCGGAAAGCAGAGCTGGTGGCACAGATGATGGAGTTCATCAGGGCAGAGCCCCCGGACTCCTTGAGGACACCTA
TTCGGAAGAAAGCCATGCTCACCTGCACTTACTTGGTCTCCGTGGAGCCAGCGCTGGACGAGCAGGCCCGGGCGGATGTGATCCATGGCT
GCCTGCACAGCATCATGGCCCTGCTGCCTGAGCCCAAGGAGGAGGACGGAGGCTGCCAGAAGTCCCTGTATCTGGAGACACTGCACGCCC
TTGAGGATCTGCTGACGAGCCTCCTGCAGCGGAACATGACCCCCCAAGGCCTGCAGATCATGATTGAGCACCTGAGCCCATGGATCAAGT
CCCCAAGAGGTCACGAGCGGGCGCGGGCCCTGGGCCTGAGCGCCCTCCTGCTGCGCTACTTCCTGGAGCACCTGCGTGTCAGCGCCCTGG
TGCCCTTCCACAACCTGGGCCTTCTCATCGGCCTCTTCTCCCCACGGTGTGCGGACCTGTGGCCTGCCACCCGCCAGGAGGCCGTGGACT
GTGTCTACTCCCTGCTGTACCTCCAGCTCGGCTATGAGGGCTTCTCCCGGGACTACCGCGATGACGTGGCGGAGCGGCTCCTCAGCCTCA
AGGACGGCCTCGTGCACCCTGACCCCGCCATTCTCTTCCACACCTGCCACAGTGTAGGCCAGATTATTGCCAAGCGCCTCCCCCCAGACC
AGCTCATCAGCCTCTTGCTAACCATGTTTGAGGCCCTGGGAGACCCCGAAAAGAACTGCTCCCGAGCAGCTACCGTCATGATCAACTGCC
TGCTGCAGGAGCGGGGCGGTGTGCTCCAGGAGAAGGTGCCCGAGATCGTGAGCGTCCTGCGCTCCAAGCTTCAGGAGGCCCAGGGAGAGC
ACGTCCTGCCGGCCGCCCAGCACAGCGTGTACCTCCTGGCCACCCAGCACTGCGCAGCCGTGGTGTCCAGCCTCCTGGGCAGCCCCTTGC
CCTTGGACAGCCACACCTGCATGCTGTGGCGGGCGCTGGCGGTGGAGCCTCGCCTAGCTGCCCAGGTCCTGGGGCTGCTGCTGGAGAAGA
TGAGTAGGGACGTCCCTTTCAAGGAGAGCCGGGCCTTCCTGCTGGGCCGCACCCCAGACCGCGTGGCCACGCTGCTGCCTCTCTCGGCTA
CCTGTGCACTGTTTGAGGTCATGTCCACGCCTGCAGCGGGGCCCGCGGTGCTCGAGCTCTACCCCCAGCTGTTTGTGGTGCTTCTGCTGC
GCGTCAGCTGCACCGTGGGTGTCCAGCTGCCCCGGAACCTGCAGGCCCAGGAAAGGAGGGGTGCCAGTCCAGCCCTAGCCACCAGGAACC
TGGAACCCTGCAGCTCTGCAGTGGACACCCTGCGGTCCATGCTACTCCGCAGCGGCAGCGAGGATGTGGTACAGCGCATGGACCTGGAGG
GAGGCTGGGAACTGCTCAGGACCTCGGCGGGGCATGAGGAGGGGGCCACCAGGTTGGCCAGGGCCATGGCTGAGCACGCAGGGCCCCGAC
TCCCCCTGGTGCTGAAGACGCTGGCATGCACACACAGCAGTGCGTATGAGAACCAGAGGGTGACCACCACCGCCTTCCTGGCCGAGCTGC
TGAACAGCAACGTGGCCAACGACCTCATGCTCTTGGACTCGCTGCTGGAGAGCCTGGCGGCTCGCCAGAAGGACACATGCGCCAGCGTGC
GGAGGCTGGTGCTCCGCGGCCTGGCCAACCTGGCCTCCGGCTGCCCTGACAAGGTGCGAACCCACGGCCCCCAGCTCCTCACAGCCATGA
TTGGCGGGCTGGACGACGGGGACAACCCTCACAGCCCAGTGGCCCTGGAGGCCATGCTGGGCCTTGCGAGGCTGGTGCACCTGGTGGAGT
CCTGGGACCTGCGCTCAGGGCTGCTGCACGTGGCCATCCGCATCCGGCCTTTCTTCGACAGTGAGAAGATGGAGTTCCGGACGGCATCTA
TCCGCCTCTTTGGGCACCTTAACAAGGTCTGCCACGGAGACTGTGAGGACGTCTTCCTGGACCAGGTGGTGGGCGGGCTGGCGCCCCTGC
TGCTGCACCTGCAGGACCCTCAGGCCACCGTGGCCAGCGCCTGCAGGTTTGCCCTGCGCATGTGTGGCCCCAATCTGGCATGTGAGGAGC
TCTCAGCTGCTTTCCAGAAACACCTGCAGGAGGGCCGAGCCCTGCACTTCGGGGAGTTCCTCAACACCACCTGCAAGCACCTGATGCACC
ATTTCCCAGACCTGCTGGGCCGTCTCCTGACCACCTGCCTGTTCTACTTCAAGAGCAGCTGGGAGAACGTCCGAGCTGCTGCACCCCTGT
TCACCGGGTTCCTGGTGCTGCACTCGGAGCCCAGGCAGCAGCCGCAGGTGGACCTGGACCAGCTCATTGCGGCGCTCCAGATCCTGCTGA
AGGACCCGGCCCCCGAGGTGCGGACGAGGGCTGCTGAGGCCCTGGGCCGCCTGGTGAAGCTCGCCTAAGGCTCCGGCCAGCACCCCCAGC
GAGGAGTATGCACCCAGACCTGTGCCTGAGCTCCAAGACAGGGCCTCCTGAGGACCACAGCCTGGGCACACGACTGGAGGGGCCTGGCCC

>In-frame_ENST00000378625_ENST00000528919_TCGA-04-1361-01A_NADK_chr1_1696667_-_MROH1_chr8_145245687_length(amino acids)=1495AA_start in transcript=260_stop in transcript=4747
MLTAARPATAMRPGVTTTPSGAGPSLAACLPRPPWGAPRSSALQRFSEGALEYLANLDRAPDPTVRKDAFATDIFSAYDVLFHQWLQSRE
AKLRLAVVEALGPMSHLLPSERLEEQLPKLLPGILALYKKHAETFYLSKSLGQILEAAVSVGSRTLETQLDALLAALHSQICVPVESSSP
LVMSNQKEVLRCFTVLACSSPDRLLAFLLPRLDTSNERTRVGTLQVVRHVINSAAAQMEDKKPFILSSMRLPLLDTNSKVKRAVVQVISA
MAHHGYLEQPGGEAMIEYIVQQCALPPEQEPEKPGPGSKDPKADSVRAISVRTLYLVSTTVDRMSHVLWPYLLQFLTPVRFTGALTPLCR
SLVHLAQKRQEAGADAFLIQYDAHASLPSPYAVTGRLLVVSSSPYLGDGRGAAALRLLSVLHPNIHPLLGQHWETTVPLLLGYLDEHTEE
TLPQEEWEEKLLMFLRDTLAIISDNAWICQLSLELCRQLPCYDEAPQEKNFLYKCIGTTLGAASSKEVVRKHLQELLETARYQEEAEREG
LACCFGICAISHLEDTLAQLEDFVRSEVFRKSIGILNIFKDRSENEVEKVKSALILCYGHVAARAPRELVLAKVESDILRNICQHFSTKV
LGIKVETKDPALKLCLVQSVCMVSRAICSSTQAGSFHFTRKAELVAQMMEFIRAEPPDSLRTPIRKKAMLTCTYLVSVEPALDEQARADV
IHGCLHSIMALLPEPKEEDGGCQKSLYLETLHALEDLLTSLLQRNMTPQGLQIMIEHLSPWIKSPRGHERARALGLSALLLRYFLEHLRV
SALVPFHNLGLLIGLFSPRCADLWPATRQEAVDCVYSLLYLQLGYEGFSRDYRDDVAERLLSLKDGLVHPDPAILFHTCHSVGQIIAKRL
PPDQLISLLLTMFEALGDPEKNCSRAATVMINCLLQERGGVLQEKVPEIVSVLRSKLQEAQGEHVLPAAQHSVYLLATQHCAAVVSSLLG
SPLPLDSHTCMLWRALAVEPRLAAQVLGLLLEKMSRDVPFKESRAFLLGRTPDRVATLLPLSATCALFEVMSTPAAGPAVLELYPQLFVV
LLLRVSCTVGVQLPRNLQAQERRGASPALATRNLEPCSSAVDTLRSMLLRSGSEDVVQRMDLEGGWELLRTSAGHEEGATRLARAMAEHA
GPRLPLVLKTLACTHSSAYENQRVTTTAFLAELLNSNVANDLMLLDSLLESLAARQKDTCASVRRLVLRGLANLASGCPDKVRTHGPQLL
TAMIGGLDDGDNPHSPVALEAMLGLARLVHLVESWDLRSGLLHVAIRIRPFFDSEKMEFRTASIRLFGHLNKVCHGDCEDVFLDQVVGGL
APLLLHLQDPQATVASACRFALRMCGPNLACEELSAAFQKHLQEGRALHFGEFLNTTCKHLMHHFPDLLGRLLTTCLFYFKSSWENVRAA

--------------------------------------------------------------
>In-frame_ENST00000378625_ENST00000326134_TCGA-04-1361-01A_NADK_chr1_1696667_-_MROH1_chr8_145245687_length(transcript)=4948nt_BP=384nt
AAATCCCCCAAGTTCTCATGATCCTTGCTTCCCTTTCCAGTCACCCTTGGTGCCCTGTACTTCACTGTGGTCCTGAACTGAAGAGCTGTG
TTTTTCAGGAAGACTTGGCCAGGCCGTGTTCCGTGTCTCTGGATTCAAGTCCCAGGAGTCCTGACCAGAGAGCAGGCATCAGTGTTTTTC
TGACCGAAGTTCTCATTTCCTGACAATGGAAATGGAACAAGAAAAAATGACCATGAATAAGGAATTGAGTCCAGACGCGGCTGCTTACTG
CTGCTCGGCCTGCCACGGCGATGAGACCTGGAGTTACAACCACCCCATCCGGGGCCGGGCCAAGTCTCGCAGCCTGTCTGCCTCGCCCGC
CCTGGGGAGCACCAAGGAGTTCAGCTCTGCAGCGCTTCAGCGAGGGTGCCCTGGAGTACCTAGCCAACCTGGACCGAGCCCCAGACCCCA
CGGTCAGGAAGGACGCCTTTGCCACCGACATCTTCAGCGCCTACGATGTTCTCTTCCATCAGTGGCTGCAGAGTCGAGAAGCCAAGCTCC
GTCTTGCCGTGGTGGAGGCTCTGGGGCCTATGAGCCATCTGCTGCCCAGTGAGAGGCTGGAAGAGCAGCTGCCCAAGCTCCTCCCTGGGA
TTCTCGCCCTCTACAAGAAGCACGCAGAGACCTTCTACTTGTCCAAGAGCCTGGGCCAGATCCTCGAGGCAGCTGTGAGTGTGGGCAGCC
GCACACTGGAGACCCAGCTGGATGCCCTCTTGGCTGCACTGCACTCCCAGATCTGTGTGCCTGTGGAGTCCTCAAGCCCCCTGGTGATGA
GTAACCAGAAGGAGGTGCTGCGCTGCTTCACTGTGCTGGCCTGCAGCTCGCCTGACCGCCTACTGGCCTTCCTGCTGCCCAGGCTGGACA
CCAGCAATGAGAGGACCCGCGTGGGCACCCTGCAGGTGGTCAGACATGTCATCAACTCAGCTGCTGCTCAGATGGAAGATAAAAAGCCCT
TTATCCTGTCTTCCATGAGGCTTCCTCTCCTGGACACCAACAGCAAGGTGAAGCGGGCAGTGGTGCAGGTGATTAGCGCCATGGCCCACC
ACGGCTACCTGGAGCAGCCTGGAGGTGAGGCGATGATCGAGTACATCGTGCAGCAGTGCGCGCTGCCCCCCGAGCAGGAGCCTGAGAAGC
CAGGCCCCGGCAGCAAGGACCCCAAGGCCGACAGCGTGCGGGCCATCAGCGTGCGCACCCTCTACCTGGTCAGCACCACCGTGGACAGGA
TGAGTCACGTCCTCTGGCCATACCTGCTCCAGTTCCTCACCCCTGTGCGCTTCACTGGGGCCCTGACTCCGCTCTGCAGGAGCCTCGTGC
ATCTGGCGCAGAAGAGGCAGGAGGCCGGGGCCGACGCCTTCCTCATCCAGTACGACGCCCATGCGAGCCTCCCGTCTCCCTATGCTGTAA
CCGGAAGACTGTTGGTTGTGTCTTCCAGCCCCTACCTAGGGGACGGACGTGGGGCAGCGGCGCTGCGCCTCCTCAGTGTTCTGCACCCAA
ACATTCACCCTTTGCTGGGTCAGCATTGGGAAACGACTGTCCCGCTGCTGCTGGGGTACCTGGATGAGCACACAGAAGAGACCCTGCCAC
AGGAGGAGTGGGAGGAGAAGCTGTTGATGTTCCTGCGAGACACCCTGGCCATCATTTCTGACAACGCGTGGATCTGCCAGCTGAGCCTGG
AGCTGTGCAGGCAGCTGCCCTGCTACGATGAGGCACCCCAGGAGAAGAACTTCCTGTACAAATGCATAGGCACCACCCTGGGTGCTGCTT
CAAGTAAGGAGGTGGTGAGGAAGCACCTTCAAGAGCTGCTGGAGACGGCCAGATACCAGGAGGAGGCAGAACGCGAGGGCCTCGCCTGCT
GCTTCGGGATCTGTGCCATCTCCCACCTCGAGGACACGCTGGCCCAGCTGGAGGACTTCGTGAGGTCAGAGGTCTTCAGAAAATCCATTG
GCATTCTCAACATTTTTAAGGATCGAAGTGAGAACGAAGTGGAGAAGGTGAAGAGTGCTCTGATCCTGTGCTATGGGCACGTGGCGGCCC
GGGCCCCCCGGGAGCTGGTGCTGGCCAAGGTAGAGTCAGACATCCTCCGGAACATCTGCCAGCACTTCAGCACCAAGGTTCTAGGAATAA
AGGTAGAAACCAAGGACCCAGCCCTGAAGCTGTGCCTTGTCCAGAGTGTGTGCATGGTCAGCCGCGCCATCTGCAGCAGCACCCAGGCTG
GCTCCTTCCACTTCACCCGGAAAGCAGAGCTGGTGGCACAGATGATGGAGTTCATCAGGGCAGAGCCCCCGGACTCCTTGAGGACACCTA
TTCGGAAGAAAGCCATGCTCACCTGCACTTACTTGGTCTCCGTGGAGCCAGCGCTGGACGAGCAGGCCCGGGCGGATGTGATCCATGGCT
GCCTGCACAGCATCATGGCCCTGCTGCCTGAGCCCAAGGAGGAGGACGGAGGCTGCCAGAAGTCCCTGTATCTGGAGACACTGCACGCCC
TTGAGGATCTGCTGACGAGCCTCCTGCAGCGGAACATGACCCCCCAAGGCCTGCAGATCATGATTGAGCACCTGAGCCCATGGATCAAGT
CCCCAAGAGGTCACGAGCGGGCGCGGGCCCTGGGCCTGAGCGCCCTCCTGCTGCGCTACTTCCTGGAGCACCTGCGTGTCAGCGCCCTGG
TGCCCTTCCACAACCTGGGCCTTCTCATCGGCCTCTTCTCCCCACGGTGTGCGGACCTGTGGCCTGCCACCCGCCAGGAGGCCGTGGACT
GTGTCTACTCCCTGCTGTACCTCCAGCTCGGCTATGAGGGCTTCTCCCGGGACTACCGCGATGACGTGGCGGAGCGGCTCCTCAGCCTCA
AGGACGGCCTCGTGCACCCTGACCCCGCCATTCTCTTCCACACCTGCCACAGTGTAGGCCAGATTATTGCCAAGCGCCTCCCCCCAGACC
AGCTCATCAGCCTCTTGCTAACCATGTTTGAGGCCCTGGGAGACCCCGAAAAGAACTGCTCCCGAGCAGCTACCGTCATGATCAACTGCC
TGCTGCAGGAGCGGGGCGGTGTGCTCCAGGAGAAGGTGCCCGAGATCGTGAGCGTCCTGCGCTCCAAGCTTCAGGAGGCCCAGGGAGAGC
ACGTCCTGCCGGCCGCCCAGCACAGCGTGTACCTCCTGGCCACCCAGCACTGCGCAGCCGTGGTGTCCAGCCTCCTGGGCAGCCCCTTGC
CCTTGGACAGCCACACCTGCATGCTGTGGCGGGCGCTGGCGGTGGAGCCTCGCCTAGCTGCCCAGGTCCTGGGGCTGCTGCTGGAGAAGA
TGAGTAGGGACGTCCCTTTCAAGGAGAGCCGGGCCTTCCTGCTGGGCCGCACCCCAGACCGCGTGGCCACGCTGCTGCCTCTCTCGGCTA
CCTGTGCACTGTTTGAGGTCATGTCCACGCCTGCAGCGGGGCCCGCGGTGCTCGAGCTCTACCCCCAGCTGTTTGTGGTGCTTCTGCTGC
GCGTCAGCTGCACCGTGGGTGTCCAGCTGCCCCGGAACCTGCAGGCCCAGGAAAGGAGGGGTGCCAGTCCAGCCCTAGCCACCAGGAACC
TGGAACCCTGCAGCTCTGCAGTGGACACCCTGCGGTCCATGCTACTCCGCAGCGGCAGCGAGGATGTGGTACAGCGCATGGACCTGGAGG
GAGGCTGGGAACTGCTCAGGACCTCGGCGGGGCATGAGGAGGGGGCCACCAGGTTGGCCAGGGCCATGGCTGAGCACGCAGGGCCCCGAC
TCCCCCTGGTGCTGAAGACGCTGGCATGCACACACAGCAGTGCGTATGAGAACCAGAGGGTGACCACCACCGCCTTCCTGGCCGAGCTGC
TGAACAGCAACGTGGCCAACGACCTCATGCTCTTGGACTCGCTGCTGGAGAGCCTGGCGGCTCGCCAGAAGGACACATGCGCCAGCGTGC
GGAGGCTGGTGCTCCGCGGCCTGGCCAACCTGGCCTCCGGCTGCCCTGACAAGGTGCGAACCCACGGCCCCCAGCTCCTCACAGCCATGA
TTGGCGGGCTGGACGACGGGGACAACCCTCACAGCCCAGTGGCCCTGGAGGCCATGCTGGGCCTTGCGAGGCTGGTGCACCTGGTGGAGT
CCTGGGACCTGCGCTCAGGGCTGCTGCACGTGGCCATCCGCATCCGGCCTTTCTTCGACAGTGAGAAGATGGAGTTCCGGACGGCATCTA
TCCGCCTCTTTGGGCACCTTAACAAGGTCTGCCACGGAGACTGTGAGGACGTCTTCCTGGACCAGGTGGTGGGCGGGCTGGCGCCCCTGC
TGCTGCACCTGCAGGACCCTCAGGCCACCGTGGCCAGCGCCTGCAGGTTTGCCCTGCGCATGTGTGGCCCCAATCTGGCATGTGAGGAGC
TCTCAGCTGCTTTCCAGAAACACCTGCAGGAGGGCCGAGCCCTGCACTTCGGGGAGTTCCTCAACACCACCTGCAAGCACCTGATGCACC
ATTTCCCAGACCTGCTGGGCCGTCTCCTGACCACCTGCCTGTTCTACTTCAAGAGCAGCTGGGAGAACGTCCGAGCTGCTGCACCCCTGT
TCACCGGGTTCCTGGTGCTGCACTCGGAGCCCAGGCAGCAGCCGCAGGTGGACCTGGACCAGCTCATTGCGGCGCTCCAGATCCTGCTGA
AGGACCCGGCCCCCGAGGTGCGGACGAGGGCTGCTGAGGCCCTGGGCCGCCTGGTGAAGCTCGCCTAAGGCTCCGGCCAGCACCCCCAGC
GAGGAGTATGCACCCAGACCTGTGCCTGAGCTCCAAGACAGGGCCTCCTGAGGACCACAGCCTGGGCACACGACTGGAGGGGCCTGGCCC

>In-frame_ENST00000378625_ENST00000326134_TCGA-04-1361-01A_NADK_chr1_1696667_-_MROH1_chr8_145245687_length(amino acids)=1495AA_start in transcript=260_stop in transcript=4747
MLTAARPATAMRPGVTTTPSGAGPSLAACLPRPPWGAPRSSALQRFSEGALEYLANLDRAPDPTVRKDAFATDIFSAYDVLFHQWLQSRE
AKLRLAVVEALGPMSHLLPSERLEEQLPKLLPGILALYKKHAETFYLSKSLGQILEAAVSVGSRTLETQLDALLAALHSQICVPVESSSP
LVMSNQKEVLRCFTVLACSSPDRLLAFLLPRLDTSNERTRVGTLQVVRHVINSAAAQMEDKKPFILSSMRLPLLDTNSKVKRAVVQVISA
MAHHGYLEQPGGEAMIEYIVQQCALPPEQEPEKPGPGSKDPKADSVRAISVRTLYLVSTTVDRMSHVLWPYLLQFLTPVRFTGALTPLCR
SLVHLAQKRQEAGADAFLIQYDAHASLPSPYAVTGRLLVVSSSPYLGDGRGAAALRLLSVLHPNIHPLLGQHWETTVPLLLGYLDEHTEE
TLPQEEWEEKLLMFLRDTLAIISDNAWICQLSLELCRQLPCYDEAPQEKNFLYKCIGTTLGAASSKEVVRKHLQELLETARYQEEAEREG
LACCFGICAISHLEDTLAQLEDFVRSEVFRKSIGILNIFKDRSENEVEKVKSALILCYGHVAARAPRELVLAKVESDILRNICQHFSTKV
LGIKVETKDPALKLCLVQSVCMVSRAICSSTQAGSFHFTRKAELVAQMMEFIRAEPPDSLRTPIRKKAMLTCTYLVSVEPALDEQARADV
IHGCLHSIMALLPEPKEEDGGCQKSLYLETLHALEDLLTSLLQRNMTPQGLQIMIEHLSPWIKSPRGHERARALGLSALLLRYFLEHLRV
SALVPFHNLGLLIGLFSPRCADLWPATRQEAVDCVYSLLYLQLGYEGFSRDYRDDVAERLLSLKDGLVHPDPAILFHTCHSVGQIIAKRL
PPDQLISLLLTMFEALGDPEKNCSRAATVMINCLLQERGGVLQEKVPEIVSVLRSKLQEAQGEHVLPAAQHSVYLLATQHCAAVVSSLLG
SPLPLDSHTCMLWRALAVEPRLAAQVLGLLLEKMSRDVPFKESRAFLLGRTPDRVATLLPLSATCALFEVMSTPAAGPAVLELYPQLFVV
LLLRVSCTVGVQLPRNLQAQERRGASPALATRNLEPCSSAVDTLRSMLLRSGSEDVVQRMDLEGGWELLRTSAGHEEGATRLARAMAEHA
GPRLPLVLKTLACTHSSAYENQRVTTTAFLAELLNSNVANDLMLLDSLLESLAARQKDTCASVRRLVLRGLANLASGCPDKVRTHGPQLL
TAMIGGLDDGDNPHSPVALEAMLGLARLVHLVESWDLRSGLLHVAIRIRPFFDSEKMEFRTASIRLFGHLNKVCHGDCEDVFLDQVVGGL
APLLLHLQDPQATVASACRFALRMCGPNLACEELSAAFQKHLQEGRALHFGEFLNTTCKHLMHHFPDLLGRLLTTCLFYFKSSWENVRAA

--------------------------------------------------------------

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Fusion Gene PPI Analysis for NADK-MROH1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for NADK-MROH1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for NADK-MROH1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource