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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:NDRG1-SNTB1 (FusionGDB2 ID:57631)

Fusion Gene Summary for NDRG1-SNTB1

check button Fusion gene summary
Fusion gene informationFusion gene name: NDRG1-SNTB1
Fusion gene ID: 57631
HgeneTgene
Gene symbol

NDRG1

SNTB1

Gene ID

10397

6641

Gene nameN-myc downstream regulated 1syntrophin beta 1
SynonymsCAP43|CMT4D|DRG-1|DRG1|GC4|HMSNL|NDR1|NMSL|PROXY1|RIT42|RTP|TARG1|TDD559-DAP|A1B|BSYN2|DAPA1B|SNT2|SNT2B1|TIP-43
Cytomap

8q24.22

8q24.12

Type of geneprotein-codingprotein-coding
Descriptionprotein NDRG1N-myc downstream-regulated gene 1 proteindifferentiation-related gene 1 proteinnickel-specific induction protein Cap43protein regulated by oxygen-1reducing agents and tunicamycin-responsive proteinbeta-1-syntrophin59 kDa dystrophin-associated protein A1 basic component 1dystrophin-associated protein A1, 59kD, basic component 1syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)syntrophin-2tax interaction protein 43
Modification date2020032820200313
UniProtAcc

Q92597

.
Ensembl transtripts involved in fusion geneENST00000323851, ENST00000354944, 
ENST00000521414, ENST00000537882, 
ENST00000414097, ENST00000518176, 
ENST00000522476, ENST00000518066, 
ENST00000395601, ENST00000517992, 
ENST00000519177, 
Fusion gene scores* DoF score27 X 21 X 12=68046 X 6 X 6=216
# samples 408
** MAII scorelog2(40/6804*10)=-4.08831123588866
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(8/216*10)=-1.43295940727611
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: NDRG1 [Title/Abstract] AND SNTB1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointNDRG1(134292475)-SNTB1(121706148), # samples:2
Anticipated loss of major functional domain due to fusion event.NDRG1-SNTB1 seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF.
NDRG1-SNTB1 seems lost the major protein functional domain in Hgene partner, which is a tumor suppressor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across NDRG1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across SNTB1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUADTCGA-05-4422-01ANDRG1chr8

134292475

-SNTB1chr8

121706148

-
ChimerDB4LUADTCGA-05-4422NDRG1chr8

134292474

-SNTB1chr8

121706148

-
ChimerDB4LUADTCGA-05-4422-01ANDRG1chr8

134292475

-SNTB1chr8

121706148

-
ChimerDB4LUADTCGA-05-4422-01ANDRG1chr8

134292478

-SNTB1chr8

121706151

-


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Fusion Gene ORF analysis for NDRG1-SNTB1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000323851ENST00000395601NDRG1chr8

134292475

-SNTB1chr8

121706148

-
Frame-shiftENST00000323851ENST00000517992NDRG1chr8

134292475

-SNTB1chr8

121706148

-
5CDS-5UTRENST00000323851ENST00000519177NDRG1chr8

134292475

-SNTB1chr8

121706148

-
Frame-shiftENST00000354944ENST00000395601NDRG1chr8

134292475

-SNTB1chr8

121706148

-
Frame-shiftENST00000354944ENST00000517992NDRG1chr8

134292475

-SNTB1chr8

121706148

-
5CDS-5UTRENST00000354944ENST00000519177NDRG1chr8

134292475

-SNTB1chr8

121706148

-
intron-3CDSENST00000521414ENST00000395601NDRG1chr8

134292475

-SNTB1chr8

121706148

-
intron-3CDSENST00000521414ENST00000517992NDRG1chr8

134292475

-SNTB1chr8

121706148

-
intron-5UTRENST00000521414ENST00000519177NDRG1chr8

134292475

-SNTB1chr8

121706148

-
5UTR-3CDSENST00000537882ENST00000395601NDRG1chr8

134292475

-SNTB1chr8

121706148

-
5UTR-3CDSENST00000537882ENST00000517992NDRG1chr8

134292475

-SNTB1chr8

121706148

-
5UTR-5UTRENST00000537882ENST00000519177NDRG1chr8

134292475

-SNTB1chr8

121706148

-
In-frameENST00000414097ENST00000395601NDRG1chr8

134292475

-SNTB1chr8

121706148

-
In-frameENST00000414097ENST00000517992NDRG1chr8

134292475

-SNTB1chr8

121706148

-
5CDS-5UTRENST00000414097ENST00000519177NDRG1chr8

134292475

-SNTB1chr8

121706148

-
intron-3CDSENST00000518176ENST00000395601NDRG1chr8

134292475

-SNTB1chr8

121706148

-
intron-3CDSENST00000518176ENST00000517992NDRG1chr8

134292475

-SNTB1chr8

121706148

-
intron-5UTRENST00000518176ENST00000519177NDRG1chr8

134292475

-SNTB1chr8

121706148

-
intron-3CDSENST00000522476ENST00000395601NDRG1chr8

134292475

-SNTB1chr8

121706148

-
intron-3CDSENST00000522476ENST00000517992NDRG1chr8

134292475

-SNTB1chr8

121706148

-
intron-5UTRENST00000522476ENST00000519177NDRG1chr8

134292475

-SNTB1chr8

121706148

-
intron-3CDSENST00000518066ENST00000395601NDRG1chr8

134292475

-SNTB1chr8

121706148

-
intron-3CDSENST00000518066ENST00000517992NDRG1chr8

134292475

-SNTB1chr8

121706148

-
intron-5UTRENST00000518066ENST00000519177NDRG1chr8

134292475

-SNTB1chr8

121706148

-
Frame-shiftENST00000323851ENST00000395601NDRG1chr8

134292474

-SNTB1chr8

121706148

-
Frame-shiftENST00000323851ENST00000517992NDRG1chr8

134292474

-SNTB1chr8

121706148

-
5CDS-5UTRENST00000323851ENST00000519177NDRG1chr8

134292474

-SNTB1chr8

121706148

-
Frame-shiftENST00000354944ENST00000395601NDRG1chr8

134292474

-SNTB1chr8

121706148

-
Frame-shiftENST00000354944ENST00000517992NDRG1chr8

134292474

-SNTB1chr8

121706148

-
5CDS-5UTRENST00000354944ENST00000519177NDRG1chr8

134292474

-SNTB1chr8

121706148

-
intron-3CDSENST00000521414ENST00000395601NDRG1chr8

134292474

-SNTB1chr8

121706148

-
intron-3CDSENST00000521414ENST00000517992NDRG1chr8

134292474

-SNTB1chr8

121706148

-
intron-5UTRENST00000521414ENST00000519177NDRG1chr8

134292474

-SNTB1chr8

121706148

-
5UTR-3CDSENST00000537882ENST00000395601NDRG1chr8

134292474

-SNTB1chr8

121706148

-
5UTR-3CDSENST00000537882ENST00000517992NDRG1chr8

134292474

-SNTB1chr8

121706148

-
5UTR-5UTRENST00000537882ENST00000519177NDRG1chr8

134292474

-SNTB1chr8

121706148

-
In-frameENST00000414097ENST00000395601NDRG1chr8

134292474

-SNTB1chr8

121706148

-
In-frameENST00000414097ENST00000517992NDRG1chr8

134292474

-SNTB1chr8

121706148

-
5CDS-5UTRENST00000414097ENST00000519177NDRG1chr8

134292474

-SNTB1chr8

121706148

-
intron-3CDSENST00000518176ENST00000395601NDRG1chr8

134292474

-SNTB1chr8

121706148

-
intron-3CDSENST00000518176ENST00000517992NDRG1chr8

134292474

-SNTB1chr8

121706148

-
intron-5UTRENST00000518176ENST00000519177NDRG1chr8

134292474

-SNTB1chr8

121706148

-
intron-3CDSENST00000522476ENST00000395601NDRG1chr8

134292474

-SNTB1chr8

121706148

-
intron-3CDSENST00000522476ENST00000517992NDRG1chr8

134292474

-SNTB1chr8

121706148

-
intron-5UTRENST00000522476ENST00000519177NDRG1chr8

134292474

-SNTB1chr8

121706148

-
intron-3CDSENST00000518066ENST00000395601NDRG1chr8

134292474

-SNTB1chr8

121706148

-
intron-3CDSENST00000518066ENST00000517992NDRG1chr8

134292474

-SNTB1chr8

121706148

-
intron-5UTRENST00000518066ENST00000519177NDRG1chr8

134292474

-SNTB1chr8

121706148

-
Frame-shiftENST00000323851ENST00000395601NDRG1chr8

134292478

-SNTB1chr8

121706151

-
Frame-shiftENST00000323851ENST00000517992NDRG1chr8

134292478

-SNTB1chr8

121706151

-
5CDS-5UTRENST00000323851ENST00000519177NDRG1chr8

134292478

-SNTB1chr8

121706151

-
Frame-shiftENST00000354944ENST00000395601NDRG1chr8

134292478

-SNTB1chr8

121706151

-
Frame-shiftENST00000354944ENST00000517992NDRG1chr8

134292478

-SNTB1chr8

121706151

-
5CDS-5UTRENST00000354944ENST00000519177NDRG1chr8

134292478

-SNTB1chr8

121706151

-
intron-3CDSENST00000521414ENST00000395601NDRG1chr8

134292478

-SNTB1chr8

121706151

-
intron-3CDSENST00000521414ENST00000517992NDRG1chr8

134292478

-SNTB1chr8

121706151

-
intron-5UTRENST00000521414ENST00000519177NDRG1chr8

134292478

-SNTB1chr8

121706151

-
5UTR-3CDSENST00000537882ENST00000395601NDRG1chr8

134292478

-SNTB1chr8

121706151

-
5UTR-3CDSENST00000537882ENST00000517992NDRG1chr8

134292478

-SNTB1chr8

121706151

-
5UTR-5UTRENST00000537882ENST00000519177NDRG1chr8

134292478

-SNTB1chr8

121706151

-
In-frameENST00000414097ENST00000395601NDRG1chr8

134292478

-SNTB1chr8

121706151

-
In-frameENST00000414097ENST00000517992NDRG1chr8

134292478

-SNTB1chr8

121706151

-
5CDS-5UTRENST00000414097ENST00000519177NDRG1chr8

134292478

-SNTB1chr8

121706151

-
intron-3CDSENST00000518176ENST00000395601NDRG1chr8

134292478

-SNTB1chr8

121706151

-
intron-3CDSENST00000518176ENST00000517992NDRG1chr8

134292478

-SNTB1chr8

121706151

-
intron-5UTRENST00000518176ENST00000519177NDRG1chr8

134292478

-SNTB1chr8

121706151

-
intron-3CDSENST00000522476ENST00000395601NDRG1chr8

134292478

-SNTB1chr8

121706151

-
intron-3CDSENST00000522476ENST00000517992NDRG1chr8

134292478

-SNTB1chr8

121706151

-
intron-5UTRENST00000522476ENST00000519177NDRG1chr8

134292478

-SNTB1chr8

121706151

-
intron-3CDSENST00000518066ENST00000395601NDRG1chr8

134292478

-SNTB1chr8

121706151

-
intron-3CDSENST00000518066ENST00000517992NDRG1chr8

134292478

-SNTB1chr8

121706151

-
intron-5UTRENST00000518066ENST00000519177NDRG1chr8

134292478

-SNTB1chr8

121706151

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000414097NDRG1chr8134292475-ENST00000395601SNTB1chr8121706148-51459679752012345
ENST00000414097NDRG1chr8134292475-ENST00000517992SNTB1chr8121706148-23699679752012345
ENST00000414097NDRG1chr8134292474-ENST00000395601SNTB1chr8121706148-51459679752012345
ENST00000414097NDRG1chr8134292474-ENST00000517992SNTB1chr8121706148-23699679752012345
ENST00000414097NDRG1chr8134292478-ENST00000395601SNTB1chr8121706151-51459679752012345
ENST00000414097NDRG1chr8134292478-ENST00000517992SNTB1chr8121706151-23699679752012345

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000414097ENST00000395601NDRG1chr8134292475-SNTB1chr8121706148-0.0037838740.9962161
ENST00000414097ENST00000517992NDRG1chr8134292475-SNTB1chr8121706148-0.04692930.9530707
ENST00000414097ENST00000395601NDRG1chr8134292474-SNTB1chr8121706148-0.0037838740.9962161
ENST00000414097ENST00000517992NDRG1chr8134292474-SNTB1chr8121706148-0.04692930.9530707
ENST00000414097ENST00000395601NDRG1chr8134292478-SNTB1chr8121706151-0.0037838740.9962161
ENST00000414097ENST00000517992NDRG1chr8134292478-SNTB1chr8121706151-0.04692930.9530707

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Fusion Genomic Features for NDRG1-SNTB1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for NDRG1-SNTB1


check button Go to

FGviewer for the breakpoints of chr8:134292475-chr8:121706148

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
NDRG1

Q92597

.
FUNCTION: Stress-responsive protein involved in hormone responses, cell growth, and differentiation. Acts as a tumor suppressor in many cell types. Necessary but not sufficient for p53/TP53-mediated caspase activation and apoptosis. Has a role in cell trafficking, notably of the Schwann cell, and is necessary for the maintenance and development of the peripheral nerve myelin sheath. Required for vesicular recycling of CDH1 and TF. May also function in lipid trafficking. Protects cells from spindle disruption damage. Functions in p53/TP53-dependent mitotic spindle checkpoint. Regulates microtubule dynamics and maintains euploidy. {ECO:0000269|PubMed:15247272, ECO:0000269|PubMed:15377670, ECO:0000269|PubMed:17786215, ECO:0000269|PubMed:9766676}.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneSNTB1chr8:134292474chr8:121706148ENST0000039560118322_433190.33333333333334539.0DomainPH 2
TgeneSNTB1chr8:134292474chr8:121706148ENST0000039560118482_538190.33333333333334539.0DomainNote=SU
TgeneSNTB1chr8:134292474chr8:121706148ENST0000051799207322_433190.33333333333334539.0DomainPH 2
TgeneSNTB1chr8:134292474chr8:121706148ENST0000051799207482_538190.33333333333334539.0DomainNote=SU
TgeneSNTB1chr8:134292475chr8:121706148ENST0000039560118322_433190.33333333333334539.0DomainPH 2
TgeneSNTB1chr8:134292475chr8:121706148ENST0000039560118482_538190.33333333333334539.0DomainNote=SU
TgeneSNTB1chr8:134292475chr8:121706148ENST0000051799207322_433190.33333333333334539.0DomainPH 2
TgeneSNTB1chr8:134292475chr8:121706148ENST0000051799207482_538190.33333333333334539.0DomainNote=SU
TgeneSNTB1chr8:134292478chr8:121706151ENST0000039560118322_433190.33333333333334539.0DomainPH 2
TgeneSNTB1chr8:134292478chr8:121706151ENST0000039560118482_538190.33333333333334539.0DomainNote=SU
TgeneSNTB1chr8:134292478chr8:121706151ENST0000051799207322_433190.33333333333334539.0DomainPH 2
TgeneSNTB1chr8:134292478chr8:121706151ENST0000051799207482_538190.33333333333334539.0DomainNote=SU
TgeneSNTB1chr8:134292474chr8:121706148ENST0000039560118518_538190.33333333333334539.0RegionCalmodulin-binding
TgeneSNTB1chr8:134292474chr8:121706148ENST0000051799207518_538190.33333333333334539.0RegionCalmodulin-binding
TgeneSNTB1chr8:134292475chr8:121706148ENST0000039560118518_538190.33333333333334539.0RegionCalmodulin-binding
TgeneSNTB1chr8:134292475chr8:121706148ENST0000051799207518_538190.33333333333334539.0RegionCalmodulin-binding
TgeneSNTB1chr8:134292478chr8:121706151ENST0000039560118518_538190.33333333333334539.0RegionCalmodulin-binding
TgeneSNTB1chr8:134292478chr8:121706151ENST0000051799207518_538190.33333333333334539.0RegionCalmodulin-binding

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNDRG1chr8:134292474chr8:121706148ENST00000323851-316339_36833.0395.0RegionNote=3 X 10 AA tandem repeats of G-T-R-S-R-S-H-T-S-E
HgeneNDRG1chr8:134292474chr8:121706148ENST00000414097-316339_36833.0395.0RegionNote=3 X 10 AA tandem repeats of G-T-R-S-R-S-H-T-S-E
HgeneNDRG1chr8:134292474chr8:121706148ENST00000522476-114339_3680329.0RegionNote=3 X 10 AA tandem repeats of G-T-R-S-R-S-H-T-S-E
HgeneNDRG1chr8:134292474chr8:121706148ENST00000537882-315339_3680314.0RegionNote=3 X 10 AA tandem repeats of G-T-R-S-R-S-H-T-S-E
HgeneNDRG1chr8:134292475chr8:121706148ENST00000323851-316339_36833.0395.0RegionNote=3 X 10 AA tandem repeats of G-T-R-S-R-S-H-T-S-E
HgeneNDRG1chr8:134292475chr8:121706148ENST00000414097-316339_36833.0395.0RegionNote=3 X 10 AA tandem repeats of G-T-R-S-R-S-H-T-S-E
HgeneNDRG1chr8:134292475chr8:121706148ENST00000522476-114339_3680329.0RegionNote=3 X 10 AA tandem repeats of G-T-R-S-R-S-H-T-S-E
HgeneNDRG1chr8:134292475chr8:121706148ENST00000537882-315339_3680314.0RegionNote=3 X 10 AA tandem repeats of G-T-R-S-R-S-H-T-S-E
HgeneNDRG1chr8:134292478chr8:121706151ENST00000323851-316339_36833.0395.0RegionNote=3 X 10 AA tandem repeats of G-T-R-S-R-S-H-T-S-E
HgeneNDRG1chr8:134292478chr8:121706151ENST00000414097-316339_36833.0395.0RegionNote=3 X 10 AA tandem repeats of G-T-R-S-R-S-H-T-S-E
HgeneNDRG1chr8:134292478chr8:121706151ENST00000522476-114339_3680329.0RegionNote=3 X 10 AA tandem repeats of G-T-R-S-R-S-H-T-S-E
HgeneNDRG1chr8:134292478chr8:121706151ENST00000537882-315339_3680314.0RegionNote=3 X 10 AA tandem repeats of G-T-R-S-R-S-H-T-S-E
HgeneNDRG1chr8:134292474chr8:121706148ENST00000323851-316339_34833.0395.0RepeatNote=1
HgeneNDRG1chr8:134292474chr8:121706148ENST00000323851-316349_35833.0395.0RepeatNote=2
HgeneNDRG1chr8:134292474chr8:121706148ENST00000323851-316359_36833.0395.0RepeatNote=3
HgeneNDRG1chr8:134292474chr8:121706148ENST00000414097-316339_34833.0395.0RepeatNote=1
HgeneNDRG1chr8:134292474chr8:121706148ENST00000414097-316349_35833.0395.0RepeatNote=2
HgeneNDRG1chr8:134292474chr8:121706148ENST00000414097-316359_36833.0395.0RepeatNote=3
HgeneNDRG1chr8:134292474chr8:121706148ENST00000522476-114339_3480329.0RepeatNote=1
HgeneNDRG1chr8:134292474chr8:121706148ENST00000522476-114349_3580329.0RepeatNote=2
HgeneNDRG1chr8:134292474chr8:121706148ENST00000522476-114359_3680329.0RepeatNote=3
HgeneNDRG1chr8:134292474chr8:121706148ENST00000537882-315339_3480314.0RepeatNote=1
HgeneNDRG1chr8:134292474chr8:121706148ENST00000537882-315349_3580314.0RepeatNote=2
HgeneNDRG1chr8:134292474chr8:121706148ENST00000537882-315359_3680314.0RepeatNote=3
HgeneNDRG1chr8:134292475chr8:121706148ENST00000323851-316339_34833.0395.0RepeatNote=1
HgeneNDRG1chr8:134292475chr8:121706148ENST00000323851-316349_35833.0395.0RepeatNote=2
HgeneNDRG1chr8:134292475chr8:121706148ENST00000323851-316359_36833.0395.0RepeatNote=3
HgeneNDRG1chr8:134292475chr8:121706148ENST00000414097-316339_34833.0395.0RepeatNote=1
HgeneNDRG1chr8:134292475chr8:121706148ENST00000414097-316349_35833.0395.0RepeatNote=2
HgeneNDRG1chr8:134292475chr8:121706148ENST00000414097-316359_36833.0395.0RepeatNote=3
HgeneNDRG1chr8:134292475chr8:121706148ENST00000522476-114339_3480329.0RepeatNote=1
HgeneNDRG1chr8:134292475chr8:121706148ENST00000522476-114349_3580329.0RepeatNote=2
HgeneNDRG1chr8:134292475chr8:121706148ENST00000522476-114359_3680329.0RepeatNote=3
HgeneNDRG1chr8:134292475chr8:121706148ENST00000537882-315339_3480314.0RepeatNote=1
HgeneNDRG1chr8:134292475chr8:121706148ENST00000537882-315349_3580314.0RepeatNote=2
HgeneNDRG1chr8:134292475chr8:121706148ENST00000537882-315359_3680314.0RepeatNote=3
HgeneNDRG1chr8:134292478chr8:121706151ENST00000323851-316339_34833.0395.0RepeatNote=1
HgeneNDRG1chr8:134292478chr8:121706151ENST00000323851-316349_35833.0395.0RepeatNote=2
HgeneNDRG1chr8:134292478chr8:121706151ENST00000323851-316359_36833.0395.0RepeatNote=3
HgeneNDRG1chr8:134292478chr8:121706151ENST00000414097-316339_34833.0395.0RepeatNote=1
HgeneNDRG1chr8:134292478chr8:121706151ENST00000414097-316349_35833.0395.0RepeatNote=2
HgeneNDRG1chr8:134292478chr8:121706151ENST00000414097-316359_36833.0395.0RepeatNote=3
HgeneNDRG1chr8:134292478chr8:121706151ENST00000522476-114339_3480329.0RepeatNote=1
HgeneNDRG1chr8:134292478chr8:121706151ENST00000522476-114349_3580329.0RepeatNote=2
HgeneNDRG1chr8:134292478chr8:121706151ENST00000522476-114359_3680329.0RepeatNote=3
HgeneNDRG1chr8:134292478chr8:121706151ENST00000537882-315339_3480314.0RepeatNote=1
HgeneNDRG1chr8:134292478chr8:121706151ENST00000537882-315349_3580314.0RepeatNote=2
HgeneNDRG1chr8:134292478chr8:121706151ENST00000537882-315359_3680314.0RepeatNote=3
TgeneSNTB1chr8:134292474chr8:121706148ENST00000395601182_10190.33333333333334539.0Compositional biasNote=Poly-Ala
TgeneSNTB1chr8:134292474chr8:121706148ENST00000517992072_10190.33333333333334539.0Compositional biasNote=Poly-Ala
TgeneSNTB1chr8:134292475chr8:121706148ENST00000395601182_10190.33333333333334539.0Compositional biasNote=Poly-Ala
TgeneSNTB1chr8:134292475chr8:121706148ENST00000517992072_10190.33333333333334539.0Compositional biasNote=Poly-Ala
TgeneSNTB1chr8:134292478chr8:121706151ENST00000395601182_10190.33333333333334539.0Compositional biasNote=Poly-Ala
TgeneSNTB1chr8:134292478chr8:121706151ENST00000517992072_10190.33333333333334539.0Compositional biasNote=Poly-Ala
TgeneSNTB1chr8:134292474chr8:121706148ENST0000039560118112_195190.33333333333334539.0DomainPDZ
TgeneSNTB1chr8:134292474chr8:121706148ENST000003956011819_298190.33333333333334539.0DomainPH 1
TgeneSNTB1chr8:134292474chr8:121706148ENST0000051799207112_195190.33333333333334539.0DomainPDZ
TgeneSNTB1chr8:134292474chr8:121706148ENST000005179920719_298190.33333333333334539.0DomainPH 1
TgeneSNTB1chr8:134292475chr8:121706148ENST0000039560118112_195190.33333333333334539.0DomainPDZ
TgeneSNTB1chr8:134292475chr8:121706148ENST000003956011819_298190.33333333333334539.0DomainPH 1
TgeneSNTB1chr8:134292475chr8:121706148ENST0000051799207112_195190.33333333333334539.0DomainPDZ
TgeneSNTB1chr8:134292475chr8:121706148ENST000005179920719_298190.33333333333334539.0DomainPH 1
TgeneSNTB1chr8:134292478chr8:121706151ENST0000039560118112_195190.33333333333334539.0DomainPDZ
TgeneSNTB1chr8:134292478chr8:121706151ENST000003956011819_298190.33333333333334539.0DomainPH 1
TgeneSNTB1chr8:134292478chr8:121706151ENST0000051799207112_195190.33333333333334539.0DomainPDZ
TgeneSNTB1chr8:134292478chr8:121706151ENST000005179920719_298190.33333333333334539.0DomainPH 1


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Fusion Gene Sequence for NDRG1-SNTB1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000414097_ENST00000395601_TCGA-05-4422-01A_NDRG1_chr8_134292475_-_SNTB1_chr8_121706148_length(transcript)=5145nt_BP=967nt
ACACAAACGCCTCCTCCGGGCAGGGCACACGCGCCCGCTGCACAGGCCGAGGCCCTGGACTCGGAGGGGACTGCAGAGCCGACCCACAAC
CCGGGCCCCGATGCCCCTCCCGGCCGCGCCCCTACGACTGCTTGCGCAACAGGCGGCGGCTCCAGTGGGCGCCCGCCGCGCGCTGCCGGA
GCCCAGCCCAGCCCGGCGCGCCCGGGAGGAGGGAGCAGGGAGCGGGGAAGGGGTGTGTCCCGGCTGCGTGCTGGGACTGCGAGGGTCTGG
GAGGGGCGAGGCGCGGGGGCGGGGCCGCGGCGCCTATAAAGTCGCCCTCCGCCCGGACGTAAACAAACCTCGCCTGGCTCCCAGCTGGTG
CTGAAGCTCGTCAGTTCACCATCCGCCCTCGGCTTCCGCGGGGCGCTGGGCCGCCAGCCTCGGCACCGTCCTTTCCTTTCTCCCTCGCGT
TAGGTAAGCCCGCGCCCTCTTCTCCCAGGCGCGACGCGGAGCAGAAAGGGGCCGCCCGTGCGGTGCCGCTGGAGCGCCAGGACCGCCCTT
TGTAGCCCCGCGTACTCCAGGAGTAAGCGCCCCGGAGCTGCAAGTGCGCGGTCACCCCGGGGCGCGGGCGCGAGGGGGCTTTGGGTGCAG
ACACCGCTGAAGTGGGGGGTTCAATTACGGAAAGGGAGGAAAAAAAGACAGGGTCCCATTCATCTCCCCCCTAGCTGGGGATTGGGGTTC
TGGAGGTCGGGAAGGGGGCGATGAGACGGTCCGAAAAAATACCAGGATAGCGTTTCCTGGCGTCGTCTCCGAATCCCAGCTGGCGCCGCT
GGCAGGGGTGCGCGCTGGACGTGGGTGCAGAAGGGACTAGGCAGGTGACAGCAGGGACATGTCTCGGGAGATGCAGGATGTAGACCTCGC
TGAGGTGAAGCCTTTGGTGGAGAAAGGGGAGACCATCACCGGCCTCCTGCAAGAGTTTGATGTCCAGTGAAGTACATGCGAGAAGCCACG
CCCTATGTGAAGAAAGGATCCCCAGTATCCGAGATTGGGTGGGAAACACCTCCGCCTGAATCCCCTCGGTTAGGGGGCAGCACCTCAGAC
CCCCCGTCATCGCAGTCCTTCTCCTTCCACAGAGACCGGAAAAGCATCCCCCTCAAAATGTGCTACGTCACTCGGAGTATGGCCTTGGCC
GACCCTGAGAACAGGCAGCTTGAAATCCACTCTCCAGATGCTAAGCACACGGTGATCCTAAGGAGCAAGGACTCAGCCACGGCCCAGGCA
TGGTTCAGTGCCATCCATTCCAACGTTAATGACCTGCTGACCCGAGTGATTGCTGAGGTCAGAGAGCAGCTGGGGAAAACAGGCATTGCT
GGGAGCCGAGAGATTAGGCATCTTGGCTGGCTTGCAGAAAAGGTGCCAGGGGAGAGCAAGAAACAGTGGAAACCAGCCCTGGTTGTGCTG
ACTGAGAAAGACCTTTTAATCTATGACAGCATGCCACGGAGGAAGGAAGCCTGGTTCAGCCCAGTTCACACATACCCTCTTCTTGCCACC
AGGCTGGTCCATTCAGGTCCAGGAAAGGGATCACCCCAGGCTGGTGTGGATCTGTCCTTTGCAACGCGAACTGGTACCAGGCAAGGGATT
GAAACACATCTCTTCAGAGCAGAGACCAGCAGGGACCTCTCCCACTGGACAAGGAGCATAGTACAGGGTTGCCACAATTCTGCTGAACTC
ATTGCTGAAATCAGCACTGCTTGCACCTACAAAAACCAGGAGTGCCGTTTGACCATACATTATGAGAATGGATTTTCTATTACCACTGAA
CCACAGGAGGGTGCCTTTCCCAAGACCATCATACAGTCTCCTTATGAAAAGCTCAAAATGTCTTCAGATGATGGAATCAGGATGCTGTAT
TTAGATTTTGGAGGCAAAGATGGAGAGATTCAACTGGACCTTCATTCCTGCCCCAAGCCAATTGTTTTCATCATTCATTCCTTCCTGTCA
GCTAAGATTACAAGACTGGGCTTGGTGGCCTGAAGACAGGGGTGACTTGCCTTTGAGAAAAGAAGGGCTGCAATGCCACCAGAGAACGTG
ATGTCAGACACCATCTGTAGTGAGCAGCGCACCAGATGTAGCGTGCTACAGTCAGCTTTAGCTCTCAAGAGTCGTATGTAACTGTCCCAG
ACTCCTCTGTCAGTTTCAGCAACTACAAGGGATACCCTGCGAAAGTACCATGAGAAATATCAGAGTAAAACTTTCTAGAACAGTACAAGG
TTAAAGAGGTGAGGTGACGGGAAATACACAGCATAGCTTTGAAATAATGACAACCAAGGACATGACCATTAGAACAGCATGTGCAGATCT
TAATCATCCCAGTTCCTAGGCAACTTGTTCACCAGGTACGCAAGGGCCGAATAGTTGAGAAATGGACATTCTTACCTACTCCTCCTAGCC
CCCTATCCCCAGTAACAGTGATCCCTTTTCTTATTGTGATTTATTTCCTAATTCTTGCTGAGTTGACTTTCCCTTGTAGGAAAAGAAAAA
TATTTCAAATAGAAACCCACCTTTTATTTAAGTATGAAGCAGCTGTTACTTTTTAAAAAATGAATTATCTTTCAATGGTGTAGAATGATT
CCAAAGTGTCTCCATTAGCATATACTGAGCAGGAATTAAATAAAGCATCAGATACTGATCTGAGCTGTAAGCTGGTAGAATCTGAGCCAA
AGTAGACTGCTTAAATTGATAAGCTTTGCTAAAGAGTTGTATGCACAAAGGATGATTAATTCTGGGACTATACTCACACCAAGGTCTGCT
GTCTTATAGCCAAGAATTACAGCTTTATTTATAGAGAGTGAATTATGGGTATTTTTTCAGAAAATATTGTCATCTGATATACACATAAAA
CAACTCACATTGTTGGAGTTAACTAATTATCCCCATTTCATGGTTTTCAGTGGCAACTTACTGACCCTTGTTTTTGCCTGTGCTTGTATG
CATGCATTTTCAAGCAAGTAATAAAGCAGCCTCATTTAATTCTGGATAATGCTGGGTTTTACATATAGACTGAATGCTATAATCAAATCT
ATTGACAGTATCTGCAGTTCTTTCAGAATTCCAGGGAAATAATATAACGACCTGATATCTTTCTACAGGAATATTTTCAGACATTATATA
GCACATTACTGATTTAATGCTTTTACTTTTATCTTTCAAAACAAATTCACTAAAAATAACACCTATTGATTTTGAAGTCACTTTTCTCAA
ACCTTGAAAATGAGCTCTAGGATCTCTATAAACATTTCTAACACTTTTCCTGTAGTTTACATAGACAGACATCTGTTGTTAGACCTGTGT
GTTTTTAAAGAATCATATGTTAACAAATACCCATGCAAAGAGCTTCAAAAAGTGAAACCGTGTTAAAGGAACACAATTTTTCTCACTCAG
ACATATTTGTTTATTGAATTGCAAAGTTTTATTTTAAATCAGCATTTCCCCAAAGAATATATCATATGACGCTAGTTCCAAGGGGCTTGA
CTGAGTGGTGTTTTGCTGGGGGGAGACAGGGGTTTGTTAATACACTTTACTAAATACTGAGCTGAAAAATGTTAAATAGATTTCACGATT
GCCTCCTTGAAGATTTTAAAGTTCATTGTGGTTCTTCAAGGCGAAATCCGGTGAACCATTCCTCACACTTACCTACAGGACTCTTTTCTA
ATGGAGCATCTTGTGAAGCTAGTGGGTTTTTTTGTTGTTGTTATTTGTTTTTTTTTTTTAATGCTTTAGAAAACACAGCTTTAGGATATT
GACTTTTTGTTTATTTCTATTTTCAAATGCTGAAAAGTCAAGTCCCAGTTTGAATACCATAGAAAAGCTTTGATGCATTTGTAAATTATA
TTGCACTCTTTCACTATATATTTTCAAAATCACTGGAATGTTGTTATACAAGAGAATTATAATTGTGTATTGTAAATAACATATTAAAAT
ACATATATTAATGCCAATAGTTAAATTCAACAATATGTAATCTAAGGTGCTCGGTTCTACATGAAGTATGAGTTAACTGCTCATAATTAA
GTTGCCAAGATTCTATTATATATTTATAGACAAATTAAAATGATCATAATTACAAATATGATTTCTTTATCACTTAAGCTTTGGGCTGAT
TAATATCTGTGTGGGGGTCAATGGAAACTACATTCTCTACATTTATAAACATTTAATTTAATTATTTATATTTTAGGAAAATATATTTGA
ATAAAATTAATGCATTTTCTAGAGTAAATTAAAATGTTATTAGCAAGAAATAGAAAATTTGACTAAGATAATTGTGTATATGAATCATTT
TTCCCCCAAGTTAAAATGTATCATAATAGAGAGGCTCTAATGAATCAATTTCCAATACTCATTTCTTTCTTATTTTGAATTCAAGTTACA
ATGACTTTACACTGTAGATTTTAATCTTGTCTGATGTGTGCTGGTGTGTATGACACAAACTCATAAGTCTGGATCATGCTTGGGTACAGT
CAATGAATCAACCGAGTCACTTTGAGGAATTTGTTTTTGTCCAATTTGCTCTGTGCTCAATCCCATGAATTATTAAATTTACAATGTTTG
TCCCCAAATGAAAACCAATATAAATGAATGATGTTTTAATCTGTACTTTATGGGAAGTTGCCTATTTGTCAGTAGATGTGGTTAAGTGAG
TCCTCTGGTGCAGTGACATCCTTTTAAGCCATCTCATAGGGATTTAAAGAAGGCCAATAGGAATATAGATATTGGTTTTTCTTTCTCTGA
CTTGAACTAAGTAGGAGAAACCAAACCATAAACCTATTACAAACTACCCAGGCAGAGGCATTTACTTAATTCATCAACTAGTGCAATTAA
AACCCTGAAAACACATGATCCTTGTTGACTCTGCTTGGTTGAAGCAGGAAAGAATGGTCTTGATGGTCAGAAAGTTTTAAAATTAATGGG
CAGGGCCTTTCTGGACCCTGTTTTCCAAACACGTTAGATATTCCGTCTTGAGGGGATTGGAGTAGGCTACAGTGAGGGGGTAATTTTTGG
ATGTATCTGGACTTTTAAAAAATGTGCCTATATTTATAGCACCATGAATATTATGTAAAATTTATATATGAATTAAATAAATATTCACCT

>In-frame_ENST00000414097_ENST00000395601_TCGA-05-4422-01A_NDRG1_chr8_134292475_-_SNTB1_chr8_121706148_length(amino acids)=345AA_start in transcript=975_stop in transcript=2012
MREATPYVKKGSPVSEIGWETPPPESPRLGGSTSDPPSSQSFSFHRDRKSIPLKMCYVTRSMALADPENRQLEIHSPDAKHTVILRSKDS
ATAQAWFSAIHSNVNDLLTRVIAEVREQLGKTGIAGSREIRHLGWLAEKVPGESKKQWKPALVVLTEKDLLIYDSMPRRKEAWFSPVHTY
PLLATRLVHSGPGKGSPQAGVDLSFATRTGTRQGIETHLFRAETSRDLSHWTRSIVQGCHNSAELIAEISTACTYKNQECRLTIHYENGF

--------------------------------------------------------------
>In-frame_ENST00000414097_ENST00000517992_TCGA-05-4422-01A_NDRG1_chr8_134292475_-_SNTB1_chr8_121706148_length(transcript)=2369nt_BP=967nt
ACACAAACGCCTCCTCCGGGCAGGGCACACGCGCCCGCTGCACAGGCCGAGGCCCTGGACTCGGAGGGGACTGCAGAGCCGACCCACAAC
CCGGGCCCCGATGCCCCTCCCGGCCGCGCCCCTACGACTGCTTGCGCAACAGGCGGCGGCTCCAGTGGGCGCCCGCCGCGCGCTGCCGGA
GCCCAGCCCAGCCCGGCGCGCCCGGGAGGAGGGAGCAGGGAGCGGGGAAGGGGTGTGTCCCGGCTGCGTGCTGGGACTGCGAGGGTCTGG
GAGGGGCGAGGCGCGGGGGCGGGGCCGCGGCGCCTATAAAGTCGCCCTCCGCCCGGACGTAAACAAACCTCGCCTGGCTCCCAGCTGGTG
CTGAAGCTCGTCAGTTCACCATCCGCCCTCGGCTTCCGCGGGGCGCTGGGCCGCCAGCCTCGGCACCGTCCTTTCCTTTCTCCCTCGCGT
TAGGTAAGCCCGCGCCCTCTTCTCCCAGGCGCGACGCGGAGCAGAAAGGGGCCGCCCGTGCGGTGCCGCTGGAGCGCCAGGACCGCCCTT
TGTAGCCCCGCGTACTCCAGGAGTAAGCGCCCCGGAGCTGCAAGTGCGCGGTCACCCCGGGGCGCGGGCGCGAGGGGGCTTTGGGTGCAG
ACACCGCTGAAGTGGGGGGTTCAATTACGGAAAGGGAGGAAAAAAAGACAGGGTCCCATTCATCTCCCCCCTAGCTGGGGATTGGGGTTC
TGGAGGTCGGGAAGGGGGCGATGAGACGGTCCGAAAAAATACCAGGATAGCGTTTCCTGGCGTCGTCTCCGAATCCCAGCTGGCGCCGCT
GGCAGGGGTGCGCGCTGGACGTGGGTGCAGAAGGGACTAGGCAGGTGACAGCAGGGACATGTCTCGGGAGATGCAGGATGTAGACCTCGC
TGAGGTGAAGCCTTTGGTGGAGAAAGGGGAGACCATCACCGGCCTCCTGCAAGAGTTTGATGTCCAGTGAAGTACATGCGAGAAGCCACG
CCCTATGTGAAGAAAGGATCCCCAGTATCCGAGATTGGGTGGGAAACACCTCCGCCTGAATCCCCTCGGTTAGGGGGCAGCACCTCAGAC
CCCCCGTCATCGCAGTCCTTCTCCTTCCACAGAGACCGGAAAAGCATCCCCCTCAAAATGTGCTACGTCACTCGGAGTATGGCCTTGGCC
GACCCTGAGAACAGGCAGCTTGAAATCCACTCTCCAGATGCTAAGCACACGGTGATCCTAAGGAGCAAGGACTCAGCCACGGCCCAGGCA
TGGTTCAGTGCCATCCATTCCAACGTTAATGACCTGCTGACCCGAGTGATTGCTGAGGTCAGAGAGCAGCTGGGGAAAACAGGCATTGCT
GGGAGCCGAGAGATTAGGCATCTTGGCTGGCTTGCAGAAAAGGTGCCAGGGGAGAGCAAGAAACAGTGGAAACCAGCCCTGGTTGTGCTG
ACTGAGAAAGACCTTTTAATCTATGACAGCATGCCACGGAGGAAGGAAGCCTGGTTCAGCCCAGTTCACACATACCCTCTTCTTGCCACC
AGGCTGGTCCATTCAGGTCCAGGAAAGGGATCACCCCAGGCTGGTGTGGATCTGTCCTTTGCAACGCGAACTGGTACCAGGCAAGGGATT
GAAACACATCTCTTCAGAGCAGAGACCAGCAGGGACCTCTCCCACTGGACAAGGAGCATAGTACAGGGTTGCCACAATTCTGCTGAACTC
ATTGCTGAAATCAGCACTGCTTGCACCTACAAAAACCAGGAGTGCCGTTTGACCATACATTATGAGAATGGATTTTCTATTACCACTGAA
CCACAGGAGGGTGCCTTTCCCAAGACCATCATACAGTCTCCTTATGAAAAGCTCAAAATGTCTTCAGATGATGGAATCAGGATGCTGTAT
TTAGATTTTGGAGGCAAAGATGGAGAGATTCAACTGGACCTTCATTCCTGCCCCAAGCCAATTGTTTTCATCATTCATTCCTTCCTGTCA
GCTAAGATTACAAGACTGGGCTTGGTGGCCTGAAGACAGGGGTGACTTGCCTTTGAGAAAAGAAGGGCTGCAATGCCACCAGAGAACGTG
ATGTCAGACACCATCTGTAGTGAGCAGCGCACCAGATGTAGCGTGCTACAGTCAGCTTTAGCTCTCAAGAGTCGTATGTAACTGTCCCAG
ACTCCTCTGTCAGTTTCAGCAACTACAAGGGATACCCTGCGAAAGTACCATGAGAAATATCAGAGTAAAACTTTCTAGAACAGTACAAGG
TTAAAGAGGTGAGGTGACGGGAAATACACAGCATAGCTTTGAAATAATGACAACCAAGGACATGACCATTAGAACAGCATGTGCAGATCT

>In-frame_ENST00000414097_ENST00000517992_TCGA-05-4422-01A_NDRG1_chr8_134292475_-_SNTB1_chr8_121706148_length(amino acids)=345AA_start in transcript=975_stop in transcript=2012
MREATPYVKKGSPVSEIGWETPPPESPRLGGSTSDPPSSQSFSFHRDRKSIPLKMCYVTRSMALADPENRQLEIHSPDAKHTVILRSKDS
ATAQAWFSAIHSNVNDLLTRVIAEVREQLGKTGIAGSREIRHLGWLAEKVPGESKKQWKPALVVLTEKDLLIYDSMPRRKEAWFSPVHTY
PLLATRLVHSGPGKGSPQAGVDLSFATRTGTRQGIETHLFRAETSRDLSHWTRSIVQGCHNSAELIAEISTACTYKNQECRLTIHYENGF

--------------------------------------------------------------
>In-frame_ENST00000414097_ENST00000395601_TCGA-05-4422_NDRG1_chr8_134292474_-_SNTB1_chr8_121706148_length(transcript)=5145nt_BP=967nt
ACACAAACGCCTCCTCCGGGCAGGGCACACGCGCCCGCTGCACAGGCCGAGGCCCTGGACTCGGAGGGGACTGCAGAGCCGACCCACAAC
CCGGGCCCCGATGCCCCTCCCGGCCGCGCCCCTACGACTGCTTGCGCAACAGGCGGCGGCTCCAGTGGGCGCCCGCCGCGCGCTGCCGGA
GCCCAGCCCAGCCCGGCGCGCCCGGGAGGAGGGAGCAGGGAGCGGGGAAGGGGTGTGTCCCGGCTGCGTGCTGGGACTGCGAGGGTCTGG
GAGGGGCGAGGCGCGGGGGCGGGGCCGCGGCGCCTATAAAGTCGCCCTCCGCCCGGACGTAAACAAACCTCGCCTGGCTCCCAGCTGGTG
CTGAAGCTCGTCAGTTCACCATCCGCCCTCGGCTTCCGCGGGGCGCTGGGCCGCCAGCCTCGGCACCGTCCTTTCCTTTCTCCCTCGCGT
TAGGTAAGCCCGCGCCCTCTTCTCCCAGGCGCGACGCGGAGCAGAAAGGGGCCGCCCGTGCGGTGCCGCTGGAGCGCCAGGACCGCCCTT
TGTAGCCCCGCGTACTCCAGGAGTAAGCGCCCCGGAGCTGCAAGTGCGCGGTCACCCCGGGGCGCGGGCGCGAGGGGGCTTTGGGTGCAG
ACACCGCTGAAGTGGGGGGTTCAATTACGGAAAGGGAGGAAAAAAAGACAGGGTCCCATTCATCTCCCCCCTAGCTGGGGATTGGGGTTC
TGGAGGTCGGGAAGGGGGCGATGAGACGGTCCGAAAAAATACCAGGATAGCGTTTCCTGGCGTCGTCTCCGAATCCCAGCTGGCGCCGCT
GGCAGGGGTGCGCGCTGGACGTGGGTGCAGAAGGGACTAGGCAGGTGACAGCAGGGACATGTCTCGGGAGATGCAGGATGTAGACCTCGC
TGAGGTGAAGCCTTTGGTGGAGAAAGGGGAGACCATCACCGGCCTCCTGCAAGAGTTTGATGTCCAGTGAAGTACATGCGAGAAGCCACG
CCCTATGTGAAGAAAGGATCCCCAGTATCCGAGATTGGGTGGGAAACACCTCCGCCTGAATCCCCTCGGTTAGGGGGCAGCACCTCAGAC
CCCCCGTCATCGCAGTCCTTCTCCTTCCACAGAGACCGGAAAAGCATCCCCCTCAAAATGTGCTACGTCACTCGGAGTATGGCCTTGGCC
GACCCTGAGAACAGGCAGCTTGAAATCCACTCTCCAGATGCTAAGCACACGGTGATCCTAAGGAGCAAGGACTCAGCCACGGCCCAGGCA
TGGTTCAGTGCCATCCATTCCAACGTTAATGACCTGCTGACCCGAGTGATTGCTGAGGTCAGAGAGCAGCTGGGGAAAACAGGCATTGCT
GGGAGCCGAGAGATTAGGCATCTTGGCTGGCTTGCAGAAAAGGTGCCAGGGGAGAGCAAGAAACAGTGGAAACCAGCCCTGGTTGTGCTG
ACTGAGAAAGACCTTTTAATCTATGACAGCATGCCACGGAGGAAGGAAGCCTGGTTCAGCCCAGTTCACACATACCCTCTTCTTGCCACC
AGGCTGGTCCATTCAGGTCCAGGAAAGGGATCACCCCAGGCTGGTGTGGATCTGTCCTTTGCAACGCGAACTGGTACCAGGCAAGGGATT
GAAACACATCTCTTCAGAGCAGAGACCAGCAGGGACCTCTCCCACTGGACAAGGAGCATAGTACAGGGTTGCCACAATTCTGCTGAACTC
ATTGCTGAAATCAGCACTGCTTGCACCTACAAAAACCAGGAGTGCCGTTTGACCATACATTATGAGAATGGATTTTCTATTACCACTGAA
CCACAGGAGGGTGCCTTTCCCAAGACCATCATACAGTCTCCTTATGAAAAGCTCAAAATGTCTTCAGATGATGGAATCAGGATGCTGTAT
TTAGATTTTGGAGGCAAAGATGGAGAGATTCAACTGGACCTTCATTCCTGCCCCAAGCCAATTGTTTTCATCATTCATTCCTTCCTGTCA
GCTAAGATTACAAGACTGGGCTTGGTGGCCTGAAGACAGGGGTGACTTGCCTTTGAGAAAAGAAGGGCTGCAATGCCACCAGAGAACGTG
ATGTCAGACACCATCTGTAGTGAGCAGCGCACCAGATGTAGCGTGCTACAGTCAGCTTTAGCTCTCAAGAGTCGTATGTAACTGTCCCAG
ACTCCTCTGTCAGTTTCAGCAACTACAAGGGATACCCTGCGAAAGTACCATGAGAAATATCAGAGTAAAACTTTCTAGAACAGTACAAGG
TTAAAGAGGTGAGGTGACGGGAAATACACAGCATAGCTTTGAAATAATGACAACCAAGGACATGACCATTAGAACAGCATGTGCAGATCT
TAATCATCCCAGTTCCTAGGCAACTTGTTCACCAGGTACGCAAGGGCCGAATAGTTGAGAAATGGACATTCTTACCTACTCCTCCTAGCC
CCCTATCCCCAGTAACAGTGATCCCTTTTCTTATTGTGATTTATTTCCTAATTCTTGCTGAGTTGACTTTCCCTTGTAGGAAAAGAAAAA
TATTTCAAATAGAAACCCACCTTTTATTTAAGTATGAAGCAGCTGTTACTTTTTAAAAAATGAATTATCTTTCAATGGTGTAGAATGATT
CCAAAGTGTCTCCATTAGCATATACTGAGCAGGAATTAAATAAAGCATCAGATACTGATCTGAGCTGTAAGCTGGTAGAATCTGAGCCAA
AGTAGACTGCTTAAATTGATAAGCTTTGCTAAAGAGTTGTATGCACAAAGGATGATTAATTCTGGGACTATACTCACACCAAGGTCTGCT
GTCTTATAGCCAAGAATTACAGCTTTATTTATAGAGAGTGAATTATGGGTATTTTTTCAGAAAATATTGTCATCTGATATACACATAAAA
CAACTCACATTGTTGGAGTTAACTAATTATCCCCATTTCATGGTTTTCAGTGGCAACTTACTGACCCTTGTTTTTGCCTGTGCTTGTATG
CATGCATTTTCAAGCAAGTAATAAAGCAGCCTCATTTAATTCTGGATAATGCTGGGTTTTACATATAGACTGAATGCTATAATCAAATCT
ATTGACAGTATCTGCAGTTCTTTCAGAATTCCAGGGAAATAATATAACGACCTGATATCTTTCTACAGGAATATTTTCAGACATTATATA
GCACATTACTGATTTAATGCTTTTACTTTTATCTTTCAAAACAAATTCACTAAAAATAACACCTATTGATTTTGAAGTCACTTTTCTCAA
ACCTTGAAAATGAGCTCTAGGATCTCTATAAACATTTCTAACACTTTTCCTGTAGTTTACATAGACAGACATCTGTTGTTAGACCTGTGT
GTTTTTAAAGAATCATATGTTAACAAATACCCATGCAAAGAGCTTCAAAAAGTGAAACCGTGTTAAAGGAACACAATTTTTCTCACTCAG
ACATATTTGTTTATTGAATTGCAAAGTTTTATTTTAAATCAGCATTTCCCCAAAGAATATATCATATGACGCTAGTTCCAAGGGGCTTGA
CTGAGTGGTGTTTTGCTGGGGGGAGACAGGGGTTTGTTAATACACTTTACTAAATACTGAGCTGAAAAATGTTAAATAGATTTCACGATT
GCCTCCTTGAAGATTTTAAAGTTCATTGTGGTTCTTCAAGGCGAAATCCGGTGAACCATTCCTCACACTTACCTACAGGACTCTTTTCTA
ATGGAGCATCTTGTGAAGCTAGTGGGTTTTTTTGTTGTTGTTATTTGTTTTTTTTTTTTAATGCTTTAGAAAACACAGCTTTAGGATATT
GACTTTTTGTTTATTTCTATTTTCAAATGCTGAAAAGTCAAGTCCCAGTTTGAATACCATAGAAAAGCTTTGATGCATTTGTAAATTATA
TTGCACTCTTTCACTATATATTTTCAAAATCACTGGAATGTTGTTATACAAGAGAATTATAATTGTGTATTGTAAATAACATATTAAAAT
ACATATATTAATGCCAATAGTTAAATTCAACAATATGTAATCTAAGGTGCTCGGTTCTACATGAAGTATGAGTTAACTGCTCATAATTAA
GTTGCCAAGATTCTATTATATATTTATAGACAAATTAAAATGATCATAATTACAAATATGATTTCTTTATCACTTAAGCTTTGGGCTGAT
TAATATCTGTGTGGGGGTCAATGGAAACTACATTCTCTACATTTATAAACATTTAATTTAATTATTTATATTTTAGGAAAATATATTTGA
ATAAAATTAATGCATTTTCTAGAGTAAATTAAAATGTTATTAGCAAGAAATAGAAAATTTGACTAAGATAATTGTGTATATGAATCATTT
TTCCCCCAAGTTAAAATGTATCATAATAGAGAGGCTCTAATGAATCAATTTCCAATACTCATTTCTTTCTTATTTTGAATTCAAGTTACA
ATGACTTTACACTGTAGATTTTAATCTTGTCTGATGTGTGCTGGTGTGTATGACACAAACTCATAAGTCTGGATCATGCTTGGGTACAGT
CAATGAATCAACCGAGTCACTTTGAGGAATTTGTTTTTGTCCAATTTGCTCTGTGCTCAATCCCATGAATTATTAAATTTACAATGTTTG
TCCCCAAATGAAAACCAATATAAATGAATGATGTTTTAATCTGTACTTTATGGGAAGTTGCCTATTTGTCAGTAGATGTGGTTAAGTGAG
TCCTCTGGTGCAGTGACATCCTTTTAAGCCATCTCATAGGGATTTAAAGAAGGCCAATAGGAATATAGATATTGGTTTTTCTTTCTCTGA
CTTGAACTAAGTAGGAGAAACCAAACCATAAACCTATTACAAACTACCCAGGCAGAGGCATTTACTTAATTCATCAACTAGTGCAATTAA
AACCCTGAAAACACATGATCCTTGTTGACTCTGCTTGGTTGAAGCAGGAAAGAATGGTCTTGATGGTCAGAAAGTTTTAAAATTAATGGG
CAGGGCCTTTCTGGACCCTGTTTTCCAAACACGTTAGATATTCCGTCTTGAGGGGATTGGAGTAGGCTACAGTGAGGGGGTAATTTTTGG
ATGTATCTGGACTTTTAAAAAATGTGCCTATATTTATAGCACCATGAATATTATGTAAAATTTATATATGAATTAAATAAATATTCACCT

>In-frame_ENST00000414097_ENST00000395601_TCGA-05-4422_NDRG1_chr8_134292474_-_SNTB1_chr8_121706148_length(amino acids)=345AA_start in transcript=975_stop in transcript=2012
MREATPYVKKGSPVSEIGWETPPPESPRLGGSTSDPPSSQSFSFHRDRKSIPLKMCYVTRSMALADPENRQLEIHSPDAKHTVILRSKDS
ATAQAWFSAIHSNVNDLLTRVIAEVREQLGKTGIAGSREIRHLGWLAEKVPGESKKQWKPALVVLTEKDLLIYDSMPRRKEAWFSPVHTY
PLLATRLVHSGPGKGSPQAGVDLSFATRTGTRQGIETHLFRAETSRDLSHWTRSIVQGCHNSAELIAEISTACTYKNQECRLTIHYENGF

--------------------------------------------------------------
>In-frame_ENST00000414097_ENST00000517992_TCGA-05-4422_NDRG1_chr8_134292474_-_SNTB1_chr8_121706148_length(transcript)=2369nt_BP=967nt
ACACAAACGCCTCCTCCGGGCAGGGCACACGCGCCCGCTGCACAGGCCGAGGCCCTGGACTCGGAGGGGACTGCAGAGCCGACCCACAAC
CCGGGCCCCGATGCCCCTCCCGGCCGCGCCCCTACGACTGCTTGCGCAACAGGCGGCGGCTCCAGTGGGCGCCCGCCGCGCGCTGCCGGA
GCCCAGCCCAGCCCGGCGCGCCCGGGAGGAGGGAGCAGGGAGCGGGGAAGGGGTGTGTCCCGGCTGCGTGCTGGGACTGCGAGGGTCTGG
GAGGGGCGAGGCGCGGGGGCGGGGCCGCGGCGCCTATAAAGTCGCCCTCCGCCCGGACGTAAACAAACCTCGCCTGGCTCCCAGCTGGTG
CTGAAGCTCGTCAGTTCACCATCCGCCCTCGGCTTCCGCGGGGCGCTGGGCCGCCAGCCTCGGCACCGTCCTTTCCTTTCTCCCTCGCGT
TAGGTAAGCCCGCGCCCTCTTCTCCCAGGCGCGACGCGGAGCAGAAAGGGGCCGCCCGTGCGGTGCCGCTGGAGCGCCAGGACCGCCCTT
TGTAGCCCCGCGTACTCCAGGAGTAAGCGCCCCGGAGCTGCAAGTGCGCGGTCACCCCGGGGCGCGGGCGCGAGGGGGCTTTGGGTGCAG
ACACCGCTGAAGTGGGGGGTTCAATTACGGAAAGGGAGGAAAAAAAGACAGGGTCCCATTCATCTCCCCCCTAGCTGGGGATTGGGGTTC
TGGAGGTCGGGAAGGGGGCGATGAGACGGTCCGAAAAAATACCAGGATAGCGTTTCCTGGCGTCGTCTCCGAATCCCAGCTGGCGCCGCT
GGCAGGGGTGCGCGCTGGACGTGGGTGCAGAAGGGACTAGGCAGGTGACAGCAGGGACATGTCTCGGGAGATGCAGGATGTAGACCTCGC
TGAGGTGAAGCCTTTGGTGGAGAAAGGGGAGACCATCACCGGCCTCCTGCAAGAGTTTGATGTCCAGTGAAGTACATGCGAGAAGCCACG
CCCTATGTGAAGAAAGGATCCCCAGTATCCGAGATTGGGTGGGAAACACCTCCGCCTGAATCCCCTCGGTTAGGGGGCAGCACCTCAGAC
CCCCCGTCATCGCAGTCCTTCTCCTTCCACAGAGACCGGAAAAGCATCCCCCTCAAAATGTGCTACGTCACTCGGAGTATGGCCTTGGCC
GACCCTGAGAACAGGCAGCTTGAAATCCACTCTCCAGATGCTAAGCACACGGTGATCCTAAGGAGCAAGGACTCAGCCACGGCCCAGGCA
TGGTTCAGTGCCATCCATTCCAACGTTAATGACCTGCTGACCCGAGTGATTGCTGAGGTCAGAGAGCAGCTGGGGAAAACAGGCATTGCT
GGGAGCCGAGAGATTAGGCATCTTGGCTGGCTTGCAGAAAAGGTGCCAGGGGAGAGCAAGAAACAGTGGAAACCAGCCCTGGTTGTGCTG
ACTGAGAAAGACCTTTTAATCTATGACAGCATGCCACGGAGGAAGGAAGCCTGGTTCAGCCCAGTTCACACATACCCTCTTCTTGCCACC
AGGCTGGTCCATTCAGGTCCAGGAAAGGGATCACCCCAGGCTGGTGTGGATCTGTCCTTTGCAACGCGAACTGGTACCAGGCAAGGGATT
GAAACACATCTCTTCAGAGCAGAGACCAGCAGGGACCTCTCCCACTGGACAAGGAGCATAGTACAGGGTTGCCACAATTCTGCTGAACTC
ATTGCTGAAATCAGCACTGCTTGCACCTACAAAAACCAGGAGTGCCGTTTGACCATACATTATGAGAATGGATTTTCTATTACCACTGAA
CCACAGGAGGGTGCCTTTCCCAAGACCATCATACAGTCTCCTTATGAAAAGCTCAAAATGTCTTCAGATGATGGAATCAGGATGCTGTAT
TTAGATTTTGGAGGCAAAGATGGAGAGATTCAACTGGACCTTCATTCCTGCCCCAAGCCAATTGTTTTCATCATTCATTCCTTCCTGTCA
GCTAAGATTACAAGACTGGGCTTGGTGGCCTGAAGACAGGGGTGACTTGCCTTTGAGAAAAGAAGGGCTGCAATGCCACCAGAGAACGTG
ATGTCAGACACCATCTGTAGTGAGCAGCGCACCAGATGTAGCGTGCTACAGTCAGCTTTAGCTCTCAAGAGTCGTATGTAACTGTCCCAG
ACTCCTCTGTCAGTTTCAGCAACTACAAGGGATACCCTGCGAAAGTACCATGAGAAATATCAGAGTAAAACTTTCTAGAACAGTACAAGG
TTAAAGAGGTGAGGTGACGGGAAATACACAGCATAGCTTTGAAATAATGACAACCAAGGACATGACCATTAGAACAGCATGTGCAGATCT

>In-frame_ENST00000414097_ENST00000517992_TCGA-05-4422_NDRG1_chr8_134292474_-_SNTB1_chr8_121706148_length(amino acids)=345AA_start in transcript=975_stop in transcript=2012
MREATPYVKKGSPVSEIGWETPPPESPRLGGSTSDPPSSQSFSFHRDRKSIPLKMCYVTRSMALADPENRQLEIHSPDAKHTVILRSKDS
ATAQAWFSAIHSNVNDLLTRVIAEVREQLGKTGIAGSREIRHLGWLAEKVPGESKKQWKPALVVLTEKDLLIYDSMPRRKEAWFSPVHTY
PLLATRLVHSGPGKGSPQAGVDLSFATRTGTRQGIETHLFRAETSRDLSHWTRSIVQGCHNSAELIAEISTACTYKNQECRLTIHYENGF

--------------------------------------------------------------
>In-frame_ENST00000414097_ENST00000395601_TCGA-05-4422-01A_NDRG1_chr8_134292478_-_SNTB1_chr8_121706151_length(transcript)=5145nt_BP=967nt
ACACAAACGCCTCCTCCGGGCAGGGCACACGCGCCCGCTGCACAGGCCGAGGCCCTGGACTCGGAGGGGACTGCAGAGCCGACCCACAAC
CCGGGCCCCGATGCCCCTCCCGGCCGCGCCCCTACGACTGCTTGCGCAACAGGCGGCGGCTCCAGTGGGCGCCCGCCGCGCGCTGCCGGA
GCCCAGCCCAGCCCGGCGCGCCCGGGAGGAGGGAGCAGGGAGCGGGGAAGGGGTGTGTCCCGGCTGCGTGCTGGGACTGCGAGGGTCTGG
GAGGGGCGAGGCGCGGGGGCGGGGCCGCGGCGCCTATAAAGTCGCCCTCCGCCCGGACGTAAACAAACCTCGCCTGGCTCCCAGCTGGTG
CTGAAGCTCGTCAGTTCACCATCCGCCCTCGGCTTCCGCGGGGCGCTGGGCCGCCAGCCTCGGCACCGTCCTTTCCTTTCTCCCTCGCGT
TAGGTAAGCCCGCGCCCTCTTCTCCCAGGCGCGACGCGGAGCAGAAAGGGGCCGCCCGTGCGGTGCCGCTGGAGCGCCAGGACCGCCCTT
TGTAGCCCCGCGTACTCCAGGAGTAAGCGCCCCGGAGCTGCAAGTGCGCGGTCACCCCGGGGCGCGGGCGCGAGGGGGCTTTGGGTGCAG
ACACCGCTGAAGTGGGGGGTTCAATTACGGAAAGGGAGGAAAAAAAGACAGGGTCCCATTCATCTCCCCCCTAGCTGGGGATTGGGGTTC
TGGAGGTCGGGAAGGGGGCGATGAGACGGTCCGAAAAAATACCAGGATAGCGTTTCCTGGCGTCGTCTCCGAATCCCAGCTGGCGCCGCT
GGCAGGGGTGCGCGCTGGACGTGGGTGCAGAAGGGACTAGGCAGGTGACAGCAGGGACATGTCTCGGGAGATGCAGGATGTAGACCTCGC
TGAGGTGAAGCCTTTGGTGGAGAAAGGGGAGACCATCACCGGCCTCCTGCAAGAGTTTGATGTCCAGTGAAGTACATGCGAGAAGCCACG
CCCTATGTGAAGAAAGGATCCCCAGTATCCGAGATTGGGTGGGAAACACCTCCGCCTGAATCCCCTCGGTTAGGGGGCAGCACCTCAGAC
CCCCCGTCATCGCAGTCCTTCTCCTTCCACAGAGACCGGAAAAGCATCCCCCTCAAAATGTGCTACGTCACTCGGAGTATGGCCTTGGCC
GACCCTGAGAACAGGCAGCTTGAAATCCACTCTCCAGATGCTAAGCACACGGTGATCCTAAGGAGCAAGGACTCAGCCACGGCCCAGGCA
TGGTTCAGTGCCATCCATTCCAACGTTAATGACCTGCTGACCCGAGTGATTGCTGAGGTCAGAGAGCAGCTGGGGAAAACAGGCATTGCT
GGGAGCCGAGAGATTAGGCATCTTGGCTGGCTTGCAGAAAAGGTGCCAGGGGAGAGCAAGAAACAGTGGAAACCAGCCCTGGTTGTGCTG
ACTGAGAAAGACCTTTTAATCTATGACAGCATGCCACGGAGGAAGGAAGCCTGGTTCAGCCCAGTTCACACATACCCTCTTCTTGCCACC
AGGCTGGTCCATTCAGGTCCAGGAAAGGGATCACCCCAGGCTGGTGTGGATCTGTCCTTTGCAACGCGAACTGGTACCAGGCAAGGGATT
GAAACACATCTCTTCAGAGCAGAGACCAGCAGGGACCTCTCCCACTGGACAAGGAGCATAGTACAGGGTTGCCACAATTCTGCTGAACTC
ATTGCTGAAATCAGCACTGCTTGCACCTACAAAAACCAGGAGTGCCGTTTGACCATACATTATGAGAATGGATTTTCTATTACCACTGAA
CCACAGGAGGGTGCCTTTCCCAAGACCATCATACAGTCTCCTTATGAAAAGCTCAAAATGTCTTCAGATGATGGAATCAGGATGCTGTAT
TTAGATTTTGGAGGCAAAGATGGAGAGATTCAACTGGACCTTCATTCCTGCCCCAAGCCAATTGTTTTCATCATTCATTCCTTCCTGTCA
GCTAAGATTACAAGACTGGGCTTGGTGGCCTGAAGACAGGGGTGACTTGCCTTTGAGAAAAGAAGGGCTGCAATGCCACCAGAGAACGTG
ATGTCAGACACCATCTGTAGTGAGCAGCGCACCAGATGTAGCGTGCTACAGTCAGCTTTAGCTCTCAAGAGTCGTATGTAACTGTCCCAG
ACTCCTCTGTCAGTTTCAGCAACTACAAGGGATACCCTGCGAAAGTACCATGAGAAATATCAGAGTAAAACTTTCTAGAACAGTACAAGG
TTAAAGAGGTGAGGTGACGGGAAATACACAGCATAGCTTTGAAATAATGACAACCAAGGACATGACCATTAGAACAGCATGTGCAGATCT
TAATCATCCCAGTTCCTAGGCAACTTGTTCACCAGGTACGCAAGGGCCGAATAGTTGAGAAATGGACATTCTTACCTACTCCTCCTAGCC
CCCTATCCCCAGTAACAGTGATCCCTTTTCTTATTGTGATTTATTTCCTAATTCTTGCTGAGTTGACTTTCCCTTGTAGGAAAAGAAAAA
TATTTCAAATAGAAACCCACCTTTTATTTAAGTATGAAGCAGCTGTTACTTTTTAAAAAATGAATTATCTTTCAATGGTGTAGAATGATT
CCAAAGTGTCTCCATTAGCATATACTGAGCAGGAATTAAATAAAGCATCAGATACTGATCTGAGCTGTAAGCTGGTAGAATCTGAGCCAA
AGTAGACTGCTTAAATTGATAAGCTTTGCTAAAGAGTTGTATGCACAAAGGATGATTAATTCTGGGACTATACTCACACCAAGGTCTGCT
GTCTTATAGCCAAGAATTACAGCTTTATTTATAGAGAGTGAATTATGGGTATTTTTTCAGAAAATATTGTCATCTGATATACACATAAAA
CAACTCACATTGTTGGAGTTAACTAATTATCCCCATTTCATGGTTTTCAGTGGCAACTTACTGACCCTTGTTTTTGCCTGTGCTTGTATG
CATGCATTTTCAAGCAAGTAATAAAGCAGCCTCATTTAATTCTGGATAATGCTGGGTTTTACATATAGACTGAATGCTATAATCAAATCT
ATTGACAGTATCTGCAGTTCTTTCAGAATTCCAGGGAAATAATATAACGACCTGATATCTTTCTACAGGAATATTTTCAGACATTATATA
GCACATTACTGATTTAATGCTTTTACTTTTATCTTTCAAAACAAATTCACTAAAAATAACACCTATTGATTTTGAAGTCACTTTTCTCAA
ACCTTGAAAATGAGCTCTAGGATCTCTATAAACATTTCTAACACTTTTCCTGTAGTTTACATAGACAGACATCTGTTGTTAGACCTGTGT
GTTTTTAAAGAATCATATGTTAACAAATACCCATGCAAAGAGCTTCAAAAAGTGAAACCGTGTTAAAGGAACACAATTTTTCTCACTCAG
ACATATTTGTTTATTGAATTGCAAAGTTTTATTTTAAATCAGCATTTCCCCAAAGAATATATCATATGACGCTAGTTCCAAGGGGCTTGA
CTGAGTGGTGTTTTGCTGGGGGGAGACAGGGGTTTGTTAATACACTTTACTAAATACTGAGCTGAAAAATGTTAAATAGATTTCACGATT
GCCTCCTTGAAGATTTTAAAGTTCATTGTGGTTCTTCAAGGCGAAATCCGGTGAACCATTCCTCACACTTACCTACAGGACTCTTTTCTA
ATGGAGCATCTTGTGAAGCTAGTGGGTTTTTTTGTTGTTGTTATTTGTTTTTTTTTTTTAATGCTTTAGAAAACACAGCTTTAGGATATT
GACTTTTTGTTTATTTCTATTTTCAAATGCTGAAAAGTCAAGTCCCAGTTTGAATACCATAGAAAAGCTTTGATGCATTTGTAAATTATA
TTGCACTCTTTCACTATATATTTTCAAAATCACTGGAATGTTGTTATACAAGAGAATTATAATTGTGTATTGTAAATAACATATTAAAAT
ACATATATTAATGCCAATAGTTAAATTCAACAATATGTAATCTAAGGTGCTCGGTTCTACATGAAGTATGAGTTAACTGCTCATAATTAA
GTTGCCAAGATTCTATTATATATTTATAGACAAATTAAAATGATCATAATTACAAATATGATTTCTTTATCACTTAAGCTTTGGGCTGAT
TAATATCTGTGTGGGGGTCAATGGAAACTACATTCTCTACATTTATAAACATTTAATTTAATTATTTATATTTTAGGAAAATATATTTGA
ATAAAATTAATGCATTTTCTAGAGTAAATTAAAATGTTATTAGCAAGAAATAGAAAATTTGACTAAGATAATTGTGTATATGAATCATTT
TTCCCCCAAGTTAAAATGTATCATAATAGAGAGGCTCTAATGAATCAATTTCCAATACTCATTTCTTTCTTATTTTGAATTCAAGTTACA
ATGACTTTACACTGTAGATTTTAATCTTGTCTGATGTGTGCTGGTGTGTATGACACAAACTCATAAGTCTGGATCATGCTTGGGTACAGT
CAATGAATCAACCGAGTCACTTTGAGGAATTTGTTTTTGTCCAATTTGCTCTGTGCTCAATCCCATGAATTATTAAATTTACAATGTTTG
TCCCCAAATGAAAACCAATATAAATGAATGATGTTTTAATCTGTACTTTATGGGAAGTTGCCTATTTGTCAGTAGATGTGGTTAAGTGAG
TCCTCTGGTGCAGTGACATCCTTTTAAGCCATCTCATAGGGATTTAAAGAAGGCCAATAGGAATATAGATATTGGTTTTTCTTTCTCTGA
CTTGAACTAAGTAGGAGAAACCAAACCATAAACCTATTACAAACTACCCAGGCAGAGGCATTTACTTAATTCATCAACTAGTGCAATTAA
AACCCTGAAAACACATGATCCTTGTTGACTCTGCTTGGTTGAAGCAGGAAAGAATGGTCTTGATGGTCAGAAAGTTTTAAAATTAATGGG
CAGGGCCTTTCTGGACCCTGTTTTCCAAACACGTTAGATATTCCGTCTTGAGGGGATTGGAGTAGGCTACAGTGAGGGGGTAATTTTTGG
ATGTATCTGGACTTTTAAAAAATGTGCCTATATTTATAGCACCATGAATATTATGTAAAATTTATATATGAATTAAATAAATATTCACCT

>In-frame_ENST00000414097_ENST00000395601_TCGA-05-4422-01A_NDRG1_chr8_134292478_-_SNTB1_chr8_121706151_length(amino acids)=345AA_start in transcript=975_stop in transcript=2012
MREATPYVKKGSPVSEIGWETPPPESPRLGGSTSDPPSSQSFSFHRDRKSIPLKMCYVTRSMALADPENRQLEIHSPDAKHTVILRSKDS
ATAQAWFSAIHSNVNDLLTRVIAEVREQLGKTGIAGSREIRHLGWLAEKVPGESKKQWKPALVVLTEKDLLIYDSMPRRKEAWFSPVHTY
PLLATRLVHSGPGKGSPQAGVDLSFATRTGTRQGIETHLFRAETSRDLSHWTRSIVQGCHNSAELIAEISTACTYKNQECRLTIHYENGF

--------------------------------------------------------------
>In-frame_ENST00000414097_ENST00000517992_TCGA-05-4422-01A_NDRG1_chr8_134292478_-_SNTB1_chr8_121706151_length(transcript)=2369nt_BP=967nt
ACACAAACGCCTCCTCCGGGCAGGGCACACGCGCCCGCTGCACAGGCCGAGGCCCTGGACTCGGAGGGGACTGCAGAGCCGACCCACAAC
CCGGGCCCCGATGCCCCTCCCGGCCGCGCCCCTACGACTGCTTGCGCAACAGGCGGCGGCTCCAGTGGGCGCCCGCCGCGCGCTGCCGGA
GCCCAGCCCAGCCCGGCGCGCCCGGGAGGAGGGAGCAGGGAGCGGGGAAGGGGTGTGTCCCGGCTGCGTGCTGGGACTGCGAGGGTCTGG
GAGGGGCGAGGCGCGGGGGCGGGGCCGCGGCGCCTATAAAGTCGCCCTCCGCCCGGACGTAAACAAACCTCGCCTGGCTCCCAGCTGGTG
CTGAAGCTCGTCAGTTCACCATCCGCCCTCGGCTTCCGCGGGGCGCTGGGCCGCCAGCCTCGGCACCGTCCTTTCCTTTCTCCCTCGCGT
TAGGTAAGCCCGCGCCCTCTTCTCCCAGGCGCGACGCGGAGCAGAAAGGGGCCGCCCGTGCGGTGCCGCTGGAGCGCCAGGACCGCCCTT
TGTAGCCCCGCGTACTCCAGGAGTAAGCGCCCCGGAGCTGCAAGTGCGCGGTCACCCCGGGGCGCGGGCGCGAGGGGGCTTTGGGTGCAG
ACACCGCTGAAGTGGGGGGTTCAATTACGGAAAGGGAGGAAAAAAAGACAGGGTCCCATTCATCTCCCCCCTAGCTGGGGATTGGGGTTC
TGGAGGTCGGGAAGGGGGCGATGAGACGGTCCGAAAAAATACCAGGATAGCGTTTCCTGGCGTCGTCTCCGAATCCCAGCTGGCGCCGCT
GGCAGGGGTGCGCGCTGGACGTGGGTGCAGAAGGGACTAGGCAGGTGACAGCAGGGACATGTCTCGGGAGATGCAGGATGTAGACCTCGC
TGAGGTGAAGCCTTTGGTGGAGAAAGGGGAGACCATCACCGGCCTCCTGCAAGAGTTTGATGTCCAGTGAAGTACATGCGAGAAGCCACG
CCCTATGTGAAGAAAGGATCCCCAGTATCCGAGATTGGGTGGGAAACACCTCCGCCTGAATCCCCTCGGTTAGGGGGCAGCACCTCAGAC
CCCCCGTCATCGCAGTCCTTCTCCTTCCACAGAGACCGGAAAAGCATCCCCCTCAAAATGTGCTACGTCACTCGGAGTATGGCCTTGGCC
GACCCTGAGAACAGGCAGCTTGAAATCCACTCTCCAGATGCTAAGCACACGGTGATCCTAAGGAGCAAGGACTCAGCCACGGCCCAGGCA
TGGTTCAGTGCCATCCATTCCAACGTTAATGACCTGCTGACCCGAGTGATTGCTGAGGTCAGAGAGCAGCTGGGGAAAACAGGCATTGCT
GGGAGCCGAGAGATTAGGCATCTTGGCTGGCTTGCAGAAAAGGTGCCAGGGGAGAGCAAGAAACAGTGGAAACCAGCCCTGGTTGTGCTG
ACTGAGAAAGACCTTTTAATCTATGACAGCATGCCACGGAGGAAGGAAGCCTGGTTCAGCCCAGTTCACACATACCCTCTTCTTGCCACC
AGGCTGGTCCATTCAGGTCCAGGAAAGGGATCACCCCAGGCTGGTGTGGATCTGTCCTTTGCAACGCGAACTGGTACCAGGCAAGGGATT
GAAACACATCTCTTCAGAGCAGAGACCAGCAGGGACCTCTCCCACTGGACAAGGAGCATAGTACAGGGTTGCCACAATTCTGCTGAACTC
ATTGCTGAAATCAGCACTGCTTGCACCTACAAAAACCAGGAGTGCCGTTTGACCATACATTATGAGAATGGATTTTCTATTACCACTGAA
CCACAGGAGGGTGCCTTTCCCAAGACCATCATACAGTCTCCTTATGAAAAGCTCAAAATGTCTTCAGATGATGGAATCAGGATGCTGTAT
TTAGATTTTGGAGGCAAAGATGGAGAGATTCAACTGGACCTTCATTCCTGCCCCAAGCCAATTGTTTTCATCATTCATTCCTTCCTGTCA
GCTAAGATTACAAGACTGGGCTTGGTGGCCTGAAGACAGGGGTGACTTGCCTTTGAGAAAAGAAGGGCTGCAATGCCACCAGAGAACGTG
ATGTCAGACACCATCTGTAGTGAGCAGCGCACCAGATGTAGCGTGCTACAGTCAGCTTTAGCTCTCAAGAGTCGTATGTAACTGTCCCAG
ACTCCTCTGTCAGTTTCAGCAACTACAAGGGATACCCTGCGAAAGTACCATGAGAAATATCAGAGTAAAACTTTCTAGAACAGTACAAGG
TTAAAGAGGTGAGGTGACGGGAAATACACAGCATAGCTTTGAAATAATGACAACCAAGGACATGACCATTAGAACAGCATGTGCAGATCT

>In-frame_ENST00000414097_ENST00000517992_TCGA-05-4422-01A_NDRG1_chr8_134292478_-_SNTB1_chr8_121706151_length(amino acids)=345AA_start in transcript=975_stop in transcript=2012
MREATPYVKKGSPVSEIGWETPPPESPRLGGSTSDPPSSQSFSFHRDRKSIPLKMCYVTRSMALADPENRQLEIHSPDAKHTVILRSKDS
ATAQAWFSAIHSNVNDLLTRVIAEVREQLGKTGIAGSREIRHLGWLAEKVPGESKKQWKPALVVLTEKDLLIYDSMPRRKEAWFSPVHTY
PLLATRLVHSGPGKGSPQAGVDLSFATRTGTRQGIETHLFRAETSRDLSHWTRSIVQGCHNSAELIAEISTACTYKNQECRLTIHYENGF

--------------------------------------------------------------

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Fusion Gene PPI Analysis for NDRG1-SNTB1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for NDRG1-SNTB1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for NDRG1-SNTB1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneNDRG1C0027627Neoplasm Metastasis2CTD_human
HgeneNDRG1C1832334CHARCOT-MARIE-TOOTH DISEASE, TYPE 4D2CTD_human;GENOMICS_ENGLAND;ORPHANET
HgeneNDRG1C0004114Astrocytoma1CTD_human
HgeneNDRG1C0006142Malignant neoplasm of breast1CTD_human
HgeneNDRG1C0007131Non-Small Cell Lung Carcinoma1CTD_human
HgeneNDRG1C0007134Renal Cell Carcinoma1CTD_human
HgeneNDRG1C0017636Glioblastoma1CTD_human
HgeneNDRG1C0022665Kidney Neoplasm1CTD_human
HgeneNDRG1C0023893Liver Cirrhosis, Experimental1CTD_human
HgeneNDRG1C0023903Liver neoplasms1CTD_human
HgeneNDRG1C0025202melanoma1CTD_human
HgeneNDRG1C0026640Mouth Neoplasms1CTD_human
HgeneNDRG1C0029295Oropharyngeal Neoplasms1CTD_human
HgeneNDRG1C0033578Prostatic Neoplasms1CTD_human
HgeneNDRG1C0149925Small cell carcinoma of lung1CTD_human
HgeneNDRG1C0153381Malignant neoplasm of mouth1CTD_human
HgeneNDRG1C0205768Subependymal Giant Cell Astrocytoma1CTD_human
HgeneNDRG1C0206658Smooth Muscle Tumor1CTD_human
HgeneNDRG1C0206734Hemangioblastoma1CTD_human
HgeneNDRG1C0279702Conventional (Clear Cell) Renal Cell Carcinoma1CTD_human
HgeneNDRG1C0280783Juvenile Pilocytic Astrocytoma1CTD_human
HgeneNDRG1C0280785Diffuse Astrocytoma1CTD_human
HgeneNDRG1C0334579Anaplastic astrocytoma1CTD_human
HgeneNDRG1C0334580Protoplasmic astrocytoma1CTD_human
HgeneNDRG1C0334581Gemistocytic astrocytoma1CTD_human
HgeneNDRG1C0334582Fibrillary Astrocytoma1CTD_human
HgeneNDRG1C0334583Pilocytic Astrocytoma1CTD_human
HgeneNDRG1C0334588Giant Cell Glioblastoma1CTD_human
HgeneNDRG1C0338070Childhood Cerebral Astrocytoma1CTD_human
HgeneNDRG1C0345904Malignant neoplasm of liver1CTD_human
HgeneNDRG1C0376358Malignant neoplasm of prostate1CTD_human
HgeneNDRG1C0547065Mixed oligoastrocytoma1CTD_human
HgeneNDRG1C0678222Breast Carcinoma1CTD_human
HgeneNDRG1C0740457Malignant neoplasm of kidney1CTD_human
HgeneNDRG1C0750935Cerebral Astrocytoma1CTD_human
HgeneNDRG1C0750936Intracranial Astrocytoma1CTD_human
HgeneNDRG1C0751692Multiple Hemangioblastomas1CTD_human
HgeneNDRG1C0887833Carcinoma, Pancreatic Ductal1CTD_human
HgeneNDRG1C1168401Squamous cell carcinoma of the head and neck1CTD_human
HgeneNDRG1C1257931Mammary Neoplasms, Human1CTD_human
HgeneNDRG1C1266042Chromophobe Renal Cell Carcinoma1CTD_human
HgeneNDRG1C1266043Sarcomatoid Renal Cell Carcinoma1CTD_human
HgeneNDRG1C1266044Collecting Duct Carcinoma of the Kidney1CTD_human
HgeneNDRG1C1306837Papillary Renal Cell Carcinoma1CTD_human
HgeneNDRG1C1458155Mammary Neoplasms1CTD_human
HgeneNDRG1C1621958Glioblastoma Multiforme1CTD_human
HgeneNDRG1C1704230Grade I Astrocytoma1CTD_human
HgeneNDRG1C2349952Oropharyngeal Carcinoma1CTD_human
HgeneNDRG1C4704874Mammary Carcinoma, Human1CTD_human