|
||||||
|
 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:NEGR1-C1orf173 (FusionGDB2 ID:58125) |
Fusion Gene Summary for NEGR1-C1orf173 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: NEGR1-C1orf173 | Fusion gene ID: 58125 | Hgene | Tgene | Gene symbol | NEGR1 | C1orf173 | Gene ID | 257194 | 127254 |
| Gene name | neuronal growth regulator 1 | glutamate rich 3 | |
| Synonyms | DMML2433|IGLON4|KILON|Ntra | C1orf173 | |
| Cytomap | 1p31.1 | 1p31.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | neuronal growth regulator 1IgLON family member 4a kindred of IgLONneurotractin | glutamate-rich protein 3RP11-653A5.1 | |
| Modification date | 20200313 | 20200313 | |
| UniProtAcc | Q7Z3B1 | . | |
| Ensembl transtripts involved in fusion gene | ENST00000357731, ENST00000306821, ENST00000434200, ENST00000467479, | ENST00000326665, ENST00000433746, ENST00000420661, | |
| Fusion gene scores | * DoF score | 16 X 11 X 7=1232 | 1 X 1 X 1=1 |
| # samples | 16 | 1 | |
| ** MAII score | log2(16/1232*10)=-2.94485844580754 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(1/1*10)=3.32192809488736 | |
| Context | PubMed: NEGR1 [Title/Abstract] AND C1orf173 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | NEGR1(72748002)-C1orf173(75114999), # samples:1 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene breakpoints across NEGR1 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
| Fusion gene breakpoints across C1orf173 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | BRCA | TCGA-OL-A5RW-01A | NEGR1 | chr1 | 72748002 | - | C1orf173 | chr1 | 75114999 | - |
Top |
Fusion Gene ORF analysis for NEGR1-C1orf173 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000357731 | ENST00000326665 | NEGR1 | chr1 | 72748002 | - | C1orf173 | chr1 | 75114999 | - |
| 5CDS-intron | ENST00000357731 | ENST00000433746 | NEGR1 | chr1 | 72748002 | - | C1orf173 | chr1 | 75114999 | - |
| 5CDS-intron | ENST00000357731 | ENST00000420661 | NEGR1 | chr1 | 72748002 | - | C1orf173 | chr1 | 75114999 | - |
| intron-3CDS | ENST00000306821 | ENST00000326665 | NEGR1 | chr1 | 72748002 | - | C1orf173 | chr1 | 75114999 | - |
| intron-intron | ENST00000306821 | ENST00000433746 | NEGR1 | chr1 | 72748002 | - | C1orf173 | chr1 | 75114999 | - |
| intron-intron | ENST00000306821 | ENST00000420661 | NEGR1 | chr1 | 72748002 | - | C1orf173 | chr1 | 75114999 | - |
| In-frame | ENST00000434200 | ENST00000326665 | NEGR1 | chr1 | 72748002 | - | C1orf173 | chr1 | 75114999 | - |
| 5CDS-intron | ENST00000434200 | ENST00000433746 | NEGR1 | chr1 | 72748002 | - | C1orf173 | chr1 | 75114999 | - |
| 5CDS-intron | ENST00000434200 | ENST00000420661 | NEGR1 | chr1 | 72748002 | - | C1orf173 | chr1 | 75114999 | - |
| intron-3CDS | ENST00000467479 | ENST00000326665 | NEGR1 | chr1 | 72748002 | - | C1orf173 | chr1 | 75114999 | - |
| intron-intron | ENST00000467479 | ENST00000433746 | NEGR1 | chr1 | 72748002 | - | C1orf173 | chr1 | 75114999 | - |
| intron-intron | ENST00000467479 | ENST00000420661 | NEGR1 | chr1 | 72748002 | - | C1orf173 | chr1 | 75114999 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000357731 | NEGR1 | chr1 | 72748002 | - | ENST00000326665 | C1orf173 | chr1 | 75114999 | - | 7333 | 416 | 240 | 4985 | 1581 |
| ENST00000434200 | NEGR1 | chr1 | 72748002 | - | ENST00000326665 | C1orf173 | chr1 | 75114999 | - | 7087 | 170 | 0 | 4739 | 1579 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000357731 | ENST00000326665 | NEGR1 | chr1 | 72748002 | - | C1orf173 | chr1 | 75114999 | - | 0.000751577 | 0.99924845 |
| ENST00000434200 | ENST00000326665 | NEGR1 | chr1 | 72748002 | - | C1orf173 | chr1 | 75114999 | - | 0.000600062 | 0.9993999 |
Top |
Fusion Genomic Features for NEGR1-C1orf173 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
Top |
Fusion Protein Features for NEGR1-C1orf173 |
| Go to FGviewer for the breakpoints of chr1:72748002-chr1:75114999 - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. |
 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| NEGR1 | . |
| FUNCTION: May be involved in cell-adhesion. May function as a trans-neural growth-promoting factor in regenerative axon sprouting in the mammalian brain (By similarity). {ECO:0000250}. | FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | C1orf173 | chr1:72748002 | chr1:75114999 | ENST00000326665 | 0 | 15 | 254_259 | 7.666666666666667 | 2993.0 | Compositional bias | Note=Poly-Arg | |
| Tgene | C1orf173 | chr1:72748002 | chr1:75114999 | ENST00000326665 | 0 | 15 | 415_1489 | 7.666666666666667 | 2993.0 | Compositional bias | Note=Glu-rich | |
| Tgene | C1orf173 | chr1:72748002 | chr1:75114999 | ENST00000420661 | 0 | 7 | 254_259 | 0 | 534.0 | Compositional bias | Note=Poly-Arg | |
| Tgene | C1orf173 | chr1:72748002 | chr1:75114999 | ENST00000420661 | 0 | 7 | 415_1489 | 0 | 534.0 | Compositional bias | Note=Glu-rich |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | NEGR1 | chr1:72748002 | chr1:75114999 | ENST00000357731 | - | 1 | 7 | 139_221 | 58.666666666666664 | 355.0 | Domain | Note=Ig-like C2-type 2 |
| Hgene | NEGR1 | chr1:72748002 | chr1:75114999 | ENST00000357731 | - | 1 | 7 | 225_313 | 58.666666666666664 | 355.0 | Domain | Note=Ig-like C2-type 3 |
| Hgene | NEGR1 | chr1:72748002 | chr1:75114999 | ENST00000357731 | - | 1 | 7 | 38_134 | 58.666666666666664 | 355.0 | Domain | Note=Ig-like C2-type 1 |
Top |
Fusion Gene Sequence for NEGR1-C1orf173 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >In-frame_ENST00000357731_ENST00000326665_TCGA-OL-A5RW-01A_NEGR1_chr1_72748002_-_C1orf173_chr1_75114999_length(transcript)=7333nt_BP=416nt GAAGAGGAGGAGGGGAGGCAAAAACACCGAAAAACAAAAAGAGAGAAACAACACCCAACAACTGGGGTGGGGGGAAGAAAGAAAGAAAAG AAACCCACCCACCCACCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAATCCTGTGGCGCGCCGCCTGGTTCCCGGGAAGACTCGCCAG CACCAGGGGGTGGGGGAGTGCGAGCTGAAAGCTGCTGGAGAGTGAGCAGCCCTAGCAGGGATGGACATGATGCTGTTGGTGCAGGGTGCT TGTTGCTCGAACCAGTGGCTGGCGGCGGTGCTCCTCAGCCTGTGCTGCCTGCTACCCTCCTGCCTCCCGGCTGGACAGAGTGTGGACTTC CCCTGGGCGGCCGTGGACAACATGATGGTCAGAAAAGGGGACACGGCGGTGCTTAGGTTACTTGCTGCATATAATAGCCTTATGGATAAA CACCTGGCTGGGTATTTTAACAATACAAGGATAAGGCGTCATCTCTTAAGATCAGGACTGATCACAAGAAGTGGAAGAATACTTTCTGAA AAAGAATATAAACTAAATATGATGAAGCGGGATCATCAAAAATATATCCGGGAATGCTTAGCCCAGGCAATTTTTCATAAAGTTCTTGAT ATGGAGCGTTACCATCAGCTTGAAATAAAAAAGAAATTGGAGACCTTAGCTAGGAAGGAGCGAATCCAGAGGTTTAAGGGAGAGCACACA AGAAGGTCTGTTGAAAATAACATGCCAATCCTGTCTCCCCACCCACCAGTTGGCCCAAAGAGTAATCGTGGCCATAGTGTTCTGGTTGAT GAAGGACATTCCAGTCCGTTAGCACTGACAGCCCCTCGACCATATACTGCTCCAGGAAATATGCAGCCTCCAATTCGATTACAGCCTCTT CCCAGTAATCCTGCAGTAGAAACTGTTCCAAAGGTAACTTCAAGGTCCAGATCAAAAACCTCATTGCTGGAAAATGAAGCTCTGTTTCCC ATTGGGGGCAAGAAGGCAGTGATGAAGTTCAGGAACTCCATAGGCAATTCACAGAGAATGAATTCATATCAACTTCCAAACATTAACAGT TACATGATGCCTATTCCTCCTCCACTTCCCCCAACTGGGAAAATCACAAGAGAAAATAGATCTGAAACATGGAGAAGGAGAAGATTTCGT CCAACCACTGCTCCAAATGGCTTAGAACCTCTTTTGACAAAGGATTCAAGAAGGATTCATAAAACATCCTTACATAGTAATGCAGCTATT ACAATGATCTATTTGGGGAAAAATGTGCACCTATCTTCTGATAATCCTGACTTCCGGGATGAAATTAAAGTTTATCAGCAGCACTGTGGT GGGGAAAACCTTTGTGTCTACAAAGGCAAACTACTTGAAAAAGAGACCTTTCAGTTTATTTCCAAAAGGCATCATGGTTTCCCCTTCAGT CTCACCTTTTTCCTGAATGGGATGCAGGTGAACAGGTTAAGCTCCTGTTGTGAATACAAGCATCGGAAAGGTTCCAGGCTTGGAGGCAAA CGAGGCTACTTTGGGTTTGTGTGTGTTGAGAGATCATCTCCTTGCTACAAGTGCATTATTGCAATGGGCCTTGACAAAAAACCGTCTTTG CCGAAATCTAGGAAAGAAAAGAGCACTGAGAAAGGAGAGGAACTGAAGAAGGCTGAGGGGAAAGTGAGGAAAGAGAGAGAGTATGTGATA CCAAAAAGAAATGAGATCAAGGAGAACAAAACCTCTGTTTCAGCCAAATTTTCAGCTCAAGAAATAAAAACAGGGCTCAAAGAAGTGGTA ACTGCTGTGGAGGAAATGACAAGTAAAGGAAAACCAGGACAAGAAGTCTTGGAAGACGACCAGGAAAATACTTTAAAATATGAGTATGAA GAAGACTTTGAAGTAGATGAGGAGAAACAAGGTGAAAAATCTAATGAAGAAGGACAGGCTGATGTTCAAATGAATGGAATACCGCAGTCA CCTTTGGATGATAAAAAAGATAATTTAGACCCTGAAAAAGAGAGTGAAACCTCATCACAGAAGGCACCAGATGCCCGTGACAATGTGAAA GATGAGAATGATGGATGCTCTGAGAGTGAACTGGAAGAGGATAAACAAGATATGAAAACTGCTTCATCAACCTCATCCAGAAGTCACCCT TATTCTAGTGACAGTGAGGATGAATCTGCAGTGGGGGACAGGGAAGCCCACACTGACAGCAGCACAGATGAAAGTGCCAGAAGGTCATCT TCTCAGGAACTGAGTGAAAATGATAAGCCAAGAAAGTCTCACCTTCCAATTGAGGAATCCTTAGAAATTGAAATTGAAGACCAAGAAATA ACAAAAGCAGATGTGGAGACCAAGCCGATGCCAATAGACGAAAGCTTTGAGAATGTTCTTAAAGAAGGAACGGAGAAAGGAACCCAAGAG ATTGCAGAGGGTTTATCTGAGAAGTCCGGGAAACATGTTTCTGCAGAAGAAAAGGAAAAGGATAAGAGTAAGCTTTGGGAAGAAAGCACT GCTCAGGTGAAGGACAAAAAGGCAGGTCTCCCTGGGTTGGAGGAAGGTGGAAAGGATTCATTGCCATTAGCCTATGTCCTGGCTCTTGGT GCACCAACAATGAATTTCATGGTGGATGAAACAGCAGCAATCAACTCAAACAAGGAATCCCAGCAATTGGTGCAAAAAACGTATACACTG GAGAAGAAAGAAGCAATGGAGGAAGATGAAGCGCCCCAGCACAGAGATGCTGACATAGTACAGGGAAAAGGGGAGGCAGCACTGTGGGGA GAAGCAGGAGCTGTTCATGAGGCTCCCTTGAGGGCGTGGAAGCCAACAGCAGAGCAGCCAGAATTGGCAGAAGAGTTTACAGAAAAAAGG GAGATCCCTCCAGGCATAGAAAGGGGGGCAGAGGGAGCAGCAGAAGCAGAAGGGGTCAGAAGGCTGGGTGAAGGGGGGTCAGACCCCATA GGACAAGCAGCAGCAAAAGATGCTGTGGGTCTGAGTAAAGATGAGGCTCCTGAAAAGCAAGCCTTGATGCTCACAGTGCTTGAGACAGAC AAAGCAGCTTCTGAAGGGGAACAGGGTTTAGAGAAGGCAGTGCTTGCAAATGAAGCAGCAGCCCTGAACTTGGAGCATCTTCATGAAGTA GCAGCCCTGAGAGAGGCAGCGACATCGGAGGAGGGAGAGGCTGAGGGTGGGGTGGCTGTGAGTGATGTCGGAGAAAGTGAAGAGGAAGCA TCCATAGACCTAGAGGACACAGGACCCATGGAGGACACAGCATCAAAGAGAGAGGACGGTTCTGAAGAGGCAATTCTTGGGGGAGAGGAA CCAGCCAAAGAGAGAAAAGAGGTTATGAGAACAGAAACACGCTTGAGCCCCTTCACAGGAGAGGCAGAGGCAAGCCGGATGCAGGTTTCG GAGGGCAGCCCTGAGGAAGGAAGCCTTGCAAAGGAAGCCTTCCTTTGCAAGGAAGATGTGGAAGGGGAAGAGATGGTGACTGAGGCAGAA GCTAATAGGGAAGATGATAGGAAAGAAATTTTACCCAAGGAATTAGATTTAGCAAGAGAGCGAAGGAAAGCTGAGAGGCCAAAAACATCT CTGAGGAAAACTGACTCTGAGAGAGAAGAGGTGACAAGGGCAAATGCACTCAAGGATGAAGATGCTTTTAAAGAAGAGCAAAAACTTAAA GCGGAAGAAGGGGAAACAGAGACAGAAGTAAGAGCTGAGGAAGAGACAAAAGCTCCCCCAAATGAAATGGGATCTGATGCTGAGAACGAA GCACCTGTGGAGGCTTCTGAGTTGTCTGACAATCCAGGGCTTCTAGGAGAAGATTCACTAAAAGAGACAGTGGTTCCCATATTTGAAGCA ACGCCTGGATTTGAAAAGTCGCTGGAAAACATAACAGCTCTGAGGAAAGAAGGAGGAGGGGAAAGACTGAGTGAAGCCAGAGACACAGAG CACAAAGACAGAGAAGAGCTGTCCAGCAGGGAGAATAGGGCCCTGAAGGAAGGGCACCGCCAAGATGGAGAGGGGGCCTTAGCAGCTCCT GAAGCTGAGCCAGCAGGAAAGGTGCAGGCCCCTGAGGGGCTGATCCCAGCCACAGGCCAGGCAGAGGAGCTAGCAGCCAAAGATCACGAC TCCTGCGCAGGACTGGAGGGGAGAGCTGAAGGGCAAGGAGGAGTGGATGTCGTGCTAAGGACCCAGGAAGCTGTTGCTGAGGAAGATCCC ATAATGGCAGAAAAGTTCAGGGAGGAAGCGGTGGATGAGGACCCAGAGGAGGAAGAGGACAAAGAGTGCACTCTGGAGACAGAAGCGATG CAGGACAGGAACTCGGAAGGGGACGGGGACATGGAAGGAGAAGGAAACACACAAAAGAATGAGGGCATGGGAGGAGGAAGGGTTGTGGCT GTGGAAGTTCTACACGGAGGTGGTGAAACGGCAGAAACAGCCGCAGAGGAGAGGGAGGTGTTGGCAGGTTCGGAGACAGCCGAGGAGAAA ACAATAGCAAATAAAGCCTCCTCCTTTTCAGATGTTGCTGAGGAAGAAACCTGGCACCAACAGGATGAGTTAGTAGGAAAAACAGCAGCT GCAGGGAAGGTGGTGGTAGAGGAATTAGCACGGAGTGGGGAGGAAGTGCCAGCAGCAGAGGAGATGACAGTGACATATACAACAGAGGCT GGGGTGGGCACTCCAGGAGCCCTGGAGCGGAAGACCTCAGGGCTAGGACAGGAGCAAGAGGAAGGGTCAGAGGGCCAGGAGGCAGCCACT GGGAGTGGCGATGGGAGGCAGGAGACAGGAGCAGCTGAAAAATTCCGATTAGGATTATCACGGGAGGGAGAGAGGGAATTGAGTCCGGAG AGTCTACAGGCGATGGCAACACTTCCAGTGAAGCCTGATTTCACTGAAACCCGAGAGAAGCAACAGCATATGGTGCAAGGAGAAAGCGAG ACTGCAGATGTTTCCCCCAACAACGTGCAGGTCTAGGAGACTTGCTGGCAGACAGATAATTTAAAGATGTCTTCTGAAGATGTAAAGAGT GGAGAAAGATTCACGCAAGCATCTCACCAGGATTCTTGATTTTCTCTCTCTCCTCTTTAGTTGCTGGTTGCGCTTGTCTGAGATGATTCC CAATCTGTCAGCCCTGGTCAGTAGCTCAGTAAGCACCTTGAGAATAGCTCAAGTAGATCTGTAGGACCCTTCTTAGAAGCAGTGGTTCCT CATGGAGAAACTTGTGAGGCTGTTACACATTCTACACACCTAACATTATTTTCAAACAAAAATGATAATTTTCAGATGCTTGACTTTTAC CAAAGATCACTGGAAGGCCCAGTCCTAATGTTAGGGGTTTGTTTAAAGTCCTTTTTATTTTACAATACAGAGCCCCAGTCAATTCCACAA TCTCAATTTCATACATGGGAATTTTATTTAAAAATCTGTGGTTTGGGGCTTTAATGAATTGGCCTGTGAAAATGAGCTCTAAATTTCCTC CCACGTACACTCAAAACTCAAGATTGCTCCAAATCTCTAAGTTCTTCCAGCAAAAGATTTCTTGGCATGTATATTCACTTATACTTAGAA ATATTCATTCTTTTAATTTATGCCAGAATAACAAAGTGGAAATCTTATTTCAAAATGCTCTTTGTTTTTTTGTGTGTGTTTCTGTAGTTC TGCTTTCTGGGGTAGACTAGTAAAATGGTAGCTTCCAGCATTTTGTCCCTGGGGCCTTCTTTATAGGGCCACTCAAATTTAAATAAAAGT AGTAAATAATTTAGCTAAGTGGAATAAGTATAATAATTATAGTGGTAAGCATAGCACATCAGCATTATGCCAACATTCTAGACTCTTTAG TTGATGTCATTAAATGGAAAAGAAACTTGGATTAAATGAGTGTGCTGCTCACCTTCCCAAGTTCTGTTATTTCAAACCTGTGAACTAACC TTGCAGTTCATTATAAATCAACAGTAACAACTGCATTCTAAATTACTCCCTGATATTATTTTCTAGTTGTGTATCAGCCTGTCTCCTAGG GGTTTTCATTTCCCTGAAGACATACAAGTGCCCCAGAGCGCATGTATATGTCTACCATTTCTCTATATGAGAAGGTAAAAAAAATTTCCT TAAGCAGTGATTTTCCAGCCAGAATATACATTAGATTTTCATGGGACGCTTTTATAAATGACTCAACCCTTTTCCCCACCCCAGAGATTC AGACTTAATTCGTTTTAGATGGATCTACACATCAGTATATATATATTTTTAACTTTTCACTTGATTCTTCTCTGTAGCCAAGGTTGAGAA CCGCTGTTCTAAATCATCATATAATCCATGCTGGCCACATTACACTCAAGGTCCCTAGGGACCAGGCATATTATCATAGTAGGTATTTTC CATTTTAATGTGTAATGGAGCCATTCAATGATCAAAAATACACTGGACCAGATAGTAGACTGGTCCCTTGATCAGAAGCATCAGCACATC AGCATCACCTGGAAATTGTTCCCAGCCTTTGTCTCCTACCTACTAAATTAGAAACTCTTGGTGGGTTCCAGTAATCCATAGCTTAACAAG CCCTGCAGTTAATACTGATGTACACTGATGTCCAAAAACTGCTGTCATGGACTATTGATTGTATTGAGGATTAGTCTCAGTTGGAAAGCC AACTACAGAGGCATTTTGAACTTTCTTTCTTTGCCTCTCTATGTCTCTCTGTCTTTTCCTGTCTTCTGATTTATCTGTCTTTCTTTCTCT AGTAAATGGCACTCAATATAAAAGTGGTGGAGTCAATCTTAAACTTATTTTTATTATGATTGTATTGATACATGCACGAAGTCCCTCTGC CCTACTCCCTATTCAAGGATATTACTCACTGCACATCATAAATCTCCATCATCTGTCTTAAAGTTTTATGAGTAGATTTCATCTACATTA TATTCAAGTTCATTTATTACTGAGCTGTATTACTGTGGAGCTCTAACAGTATTTGTTTCCTGATTTCAAACTCAATGCTACAGAGCACTT TGAATACATCACACCTTATAGGAAAGATAGTAAATGTATTAATCCCATTGAAAAATTAGTTTTGTACAATGTGCTAAATAGTATTGCATT GGATTACTTTTATATTTAACACACTCCATCAAAACATCCCATAACATAATTTTACAATCTGCATGTGAATTTAACTGTGAAATTCAGTAT TGTGATATTTTGAATAAGTGAATTCTTTCTCTGCAAATACTATGTTGATAAAATTACTTGTATGTTCCCCTGAAATGGTTTGTTTCCTGT >In-frame_ENST00000357731_ENST00000326665_TCGA-OL-A5RW-01A_NEGR1_chr1_72748002_-_C1orf173_chr1_75114999_length(amino acids)=1581AA_start in transcript=240_stop in transcript=4985 MDMMLLVQGACCSNQWLAAVLLSLCCLLPSCLPAGQSVDFPWAAVDNMMVRKGDTAVLRLLAAYNSLMDKHLAGYFNNTRIRRHLLRSGL ITRSGRILSEKEYKLNMMKRDHQKYIRECLAQAIFHKVLDMERYHQLEIKKKLETLARKERIQRFKGEHTRRSVENNMPILSPHPPVGPK SNRGHSVLVDEGHSSPLALTAPRPYTAPGNMQPPIRLQPLPSNPAVETVPKVTSRSRSKTSLLENEALFPIGGKKAVMKFRNSIGNSQRM NSYQLPNINSYMMPIPPPLPPTGKITRENRSETWRRRRFRPTTAPNGLEPLLTKDSRRIHKTSLHSNAAITMIYLGKNVHLSSDNPDFRD EIKVYQQHCGGENLCVYKGKLLEKETFQFISKRHHGFPFSLTFFLNGMQVNRLSSCCEYKHRKGSRLGGKRGYFGFVCVERSSPCYKCII AMGLDKKPSLPKSRKEKSTEKGEELKKAEGKVRKEREYVIPKRNEIKENKTSVSAKFSAQEIKTGLKEVVTAVEEMTSKGKPGQEVLEDD QENTLKYEYEEDFEVDEEKQGEKSNEEGQADVQMNGIPQSPLDDKKDNLDPEKESETSSQKAPDARDNVKDENDGCSESELEEDKQDMKT ASSTSSRSHPYSSDSEDESAVGDREAHTDSSTDESARRSSSQELSENDKPRKSHLPIEESLEIEIEDQEITKADVETKPMPIDESFENVL KEGTEKGTQEIAEGLSEKSGKHVSAEEKEKDKSKLWEESTAQVKDKKAGLPGLEEGGKDSLPLAYVLALGAPTMNFMVDETAAINSNKES QQLVQKTYTLEKKEAMEEDEAPQHRDADIVQGKGEAALWGEAGAVHEAPLRAWKPTAEQPELAEEFTEKREIPPGIERGAEGAAEAEGVR RLGEGGSDPIGQAAAKDAVGLSKDEAPEKQALMLTVLETDKAASEGEQGLEKAVLANEAAALNLEHLHEVAALREAATSEEGEAEGGVAV SDVGESEEEASIDLEDTGPMEDTASKREDGSEEAILGGEEPAKERKEVMRTETRLSPFTGEAEASRMQVSEGSPEEGSLAKEAFLCKEDV EGEEMVTEAEANREDDRKEILPKELDLARERRKAERPKTSLRKTDSEREEVTRANALKDEDAFKEEQKLKAEEGETETEVRAEEETKAPP NEMGSDAENEAPVEASELSDNPGLLGEDSLKETVVPIFEATPGFEKSLENITALRKEGGGERLSEARDTEHKDREELSSRENRALKEGHR QDGEGALAAPEAEPAGKVQAPEGLIPATGQAEELAAKDHDSCAGLEGRAEGQGGVDVVLRTQEAVAEEDPIMAEKFREEAVDEDPEEEED KECTLETEAMQDRNSEGDGDMEGEGNTQKNEGMGGGRVVAVEVLHGGGETAETAAEEREVLAGSETAEEKTIANKASSFSDVAEEETWHQ QDELVGKTAAAGKVVVEELARSGEEVPAAEEMTVTYTTEAGVGTPGALERKTSGLGQEQEEGSEGQEAATGSGDGRQETGAAEKFRLGLS -------------------------------------------------------------- >In-frame_ENST00000434200_ENST00000326665_TCGA-OL-A5RW-01A_NEGR1_chr1_72748002_-_C1orf173_chr1_75114999_length(transcript)=7087nt_BP=170nt ATGATGCTGTTGGTGCAGGGTGCTTGTTGCTCGAACCAGTGGCTGGCGGCGGTGCTCCTCAGCCTGTGCTGCCTGCTACCCTCCTGCCTC CCGGCTGGACAGAGTGTGGACTTCCCCTGGGCGGCCGTGGACAACATGATGGTCAGAAAAGGGGACACGGCGGTGCTTAGGTTACTTGCT GCATATAATAGCCTTATGGATAAACACCTGGCTGGGTATTTTAACAATACAAGGATAAGGCGTCATCTCTTAAGATCAGGACTGATCACA AGAAGTGGAAGAATACTTTCTGAAAAAGAATATAAACTAAATATGATGAAGCGGGATCATCAAAAATATATCCGGGAATGCTTAGCCCAG GCAATTTTTCATAAAGTTCTTGATATGGAGCGTTACCATCAGCTTGAAATAAAAAAGAAATTGGAGACCTTAGCTAGGAAGGAGCGAATC CAGAGGTTTAAGGGAGAGCACACAAGAAGGTCTGTTGAAAATAACATGCCAATCCTGTCTCCCCACCCACCAGTTGGCCCAAAGAGTAAT CGTGGCCATAGTGTTCTGGTTGATGAAGGACATTCCAGTCCGTTAGCACTGACAGCCCCTCGACCATATACTGCTCCAGGAAATATGCAG CCTCCAATTCGATTACAGCCTCTTCCCAGTAATCCTGCAGTAGAAACTGTTCCAAAGGTAACTTCAAGGTCCAGATCAAAAACCTCATTG CTGGAAAATGAAGCTCTGTTTCCCATTGGGGGCAAGAAGGCAGTGATGAAGTTCAGGAACTCCATAGGCAATTCACAGAGAATGAATTCA TATCAACTTCCAAACATTAACAGTTACATGATGCCTATTCCTCCTCCACTTCCCCCAACTGGGAAAATCACAAGAGAAAATAGATCTGAA ACATGGAGAAGGAGAAGATTTCGTCCAACCACTGCTCCAAATGGCTTAGAACCTCTTTTGACAAAGGATTCAAGAAGGATTCATAAAACA TCCTTACATAGTAATGCAGCTATTACAATGATCTATTTGGGGAAAAATGTGCACCTATCTTCTGATAATCCTGACTTCCGGGATGAAATT AAAGTTTATCAGCAGCACTGTGGTGGGGAAAACCTTTGTGTCTACAAAGGCAAACTACTTGAAAAAGAGACCTTTCAGTTTATTTCCAAA AGGCATCATGGTTTCCCCTTCAGTCTCACCTTTTTCCTGAATGGGATGCAGGTGAACAGGTTAAGCTCCTGTTGTGAATACAAGCATCGG AAAGGTTCCAGGCTTGGAGGCAAACGAGGCTACTTTGGGTTTGTGTGTGTTGAGAGATCATCTCCTTGCTACAAGTGCATTATTGCAATG GGCCTTGACAAAAAACCGTCTTTGCCGAAATCTAGGAAAGAAAAGAGCACTGAGAAAGGAGAGGAACTGAAGAAGGCTGAGGGGAAAGTG AGGAAAGAGAGAGAGTATGTGATACCAAAAAGAAATGAGATCAAGGAGAACAAAACCTCTGTTTCAGCCAAATTTTCAGCTCAAGAAATA AAAACAGGGCTCAAAGAAGTGGTAACTGCTGTGGAGGAAATGACAAGTAAAGGAAAACCAGGACAAGAAGTCTTGGAAGACGACCAGGAA AATACTTTAAAATATGAGTATGAAGAAGACTTTGAAGTAGATGAGGAGAAACAAGGTGAAAAATCTAATGAAGAAGGACAGGCTGATGTT CAAATGAATGGAATACCGCAGTCACCTTTGGATGATAAAAAAGATAATTTAGACCCTGAAAAAGAGAGTGAAACCTCATCACAGAAGGCA CCAGATGCCCGTGACAATGTGAAAGATGAGAATGATGGATGCTCTGAGAGTGAACTGGAAGAGGATAAACAAGATATGAAAACTGCTTCA TCAACCTCATCCAGAAGTCACCCTTATTCTAGTGACAGTGAGGATGAATCTGCAGTGGGGGACAGGGAAGCCCACACTGACAGCAGCACA GATGAAAGTGCCAGAAGGTCATCTTCTCAGGAACTGAGTGAAAATGATAAGCCAAGAAAGTCTCACCTTCCAATTGAGGAATCCTTAGAA ATTGAAATTGAAGACCAAGAAATAACAAAAGCAGATGTGGAGACCAAGCCGATGCCAATAGACGAAAGCTTTGAGAATGTTCTTAAAGAA GGAACGGAGAAAGGAACCCAAGAGATTGCAGAGGGTTTATCTGAGAAGTCCGGGAAACATGTTTCTGCAGAAGAAAAGGAAAAGGATAAG AGTAAGCTTTGGGAAGAAAGCACTGCTCAGGTGAAGGACAAAAAGGCAGGTCTCCCTGGGTTGGAGGAAGGTGGAAAGGATTCATTGCCA TTAGCCTATGTCCTGGCTCTTGGTGCACCAACAATGAATTTCATGGTGGATGAAACAGCAGCAATCAACTCAAACAAGGAATCCCAGCAA TTGGTGCAAAAAACGTATACACTGGAGAAGAAAGAAGCAATGGAGGAAGATGAAGCGCCCCAGCACAGAGATGCTGACATAGTACAGGGA AAAGGGGAGGCAGCACTGTGGGGAGAAGCAGGAGCTGTTCATGAGGCTCCCTTGAGGGCGTGGAAGCCAACAGCAGAGCAGCCAGAATTG GCAGAAGAGTTTACAGAAAAAAGGGAGATCCCTCCAGGCATAGAAAGGGGGGCAGAGGGAGCAGCAGAAGCAGAAGGGGTCAGAAGGCTG GGTGAAGGGGGGTCAGACCCCATAGGACAAGCAGCAGCAAAAGATGCTGTGGGTCTGAGTAAAGATGAGGCTCCTGAAAAGCAAGCCTTG ATGCTCACAGTGCTTGAGACAGACAAAGCAGCTTCTGAAGGGGAACAGGGTTTAGAGAAGGCAGTGCTTGCAAATGAAGCAGCAGCCCTG AACTTGGAGCATCTTCATGAAGTAGCAGCCCTGAGAGAGGCAGCGACATCGGAGGAGGGAGAGGCTGAGGGTGGGGTGGCTGTGAGTGAT GTCGGAGAAAGTGAAGAGGAAGCATCCATAGACCTAGAGGACACAGGACCCATGGAGGACACAGCATCAAAGAGAGAGGACGGTTCTGAA GAGGCAATTCTTGGGGGAGAGGAACCAGCCAAAGAGAGAAAAGAGGTTATGAGAACAGAAACACGCTTGAGCCCCTTCACAGGAGAGGCA GAGGCAAGCCGGATGCAGGTTTCGGAGGGCAGCCCTGAGGAAGGAAGCCTTGCAAAGGAAGCCTTCCTTTGCAAGGAAGATGTGGAAGGG GAAGAGATGGTGACTGAGGCAGAAGCTAATAGGGAAGATGATAGGAAAGAAATTTTACCCAAGGAATTAGATTTAGCAAGAGAGCGAAGG AAAGCTGAGAGGCCAAAAACATCTCTGAGGAAAACTGACTCTGAGAGAGAAGAGGTGACAAGGGCAAATGCACTCAAGGATGAAGATGCT TTTAAAGAAGAGCAAAAACTTAAAGCGGAAGAAGGGGAAACAGAGACAGAAGTAAGAGCTGAGGAAGAGACAAAAGCTCCCCCAAATGAA ATGGGATCTGATGCTGAGAACGAAGCACCTGTGGAGGCTTCTGAGTTGTCTGACAATCCAGGGCTTCTAGGAGAAGATTCACTAAAAGAG ACAGTGGTTCCCATATTTGAAGCAACGCCTGGATTTGAAAAGTCGCTGGAAAACATAACAGCTCTGAGGAAAGAAGGAGGAGGGGAAAGA CTGAGTGAAGCCAGAGACACAGAGCACAAAGACAGAGAAGAGCTGTCCAGCAGGGAGAATAGGGCCCTGAAGGAAGGGCACCGCCAAGAT GGAGAGGGGGCCTTAGCAGCTCCTGAAGCTGAGCCAGCAGGAAAGGTGCAGGCCCCTGAGGGGCTGATCCCAGCCACAGGCCAGGCAGAG GAGCTAGCAGCCAAAGATCACGACTCCTGCGCAGGACTGGAGGGGAGAGCTGAAGGGCAAGGAGGAGTGGATGTCGTGCTAAGGACCCAG GAAGCTGTTGCTGAGGAAGATCCCATAATGGCAGAAAAGTTCAGGGAGGAAGCGGTGGATGAGGACCCAGAGGAGGAAGAGGACAAAGAG TGCACTCTGGAGACAGAAGCGATGCAGGACAGGAACTCGGAAGGGGACGGGGACATGGAAGGAGAAGGAAACACACAAAAGAATGAGGGC ATGGGAGGAGGAAGGGTTGTGGCTGTGGAAGTTCTACACGGAGGTGGTGAAACGGCAGAAACAGCCGCAGAGGAGAGGGAGGTGTTGGCA GGTTCGGAGACAGCCGAGGAGAAAACAATAGCAAATAAAGCCTCCTCCTTTTCAGATGTTGCTGAGGAAGAAACCTGGCACCAACAGGAT GAGTTAGTAGGAAAAACAGCAGCTGCAGGGAAGGTGGTGGTAGAGGAATTAGCACGGAGTGGGGAGGAAGTGCCAGCAGCAGAGGAGATG ACAGTGACATATACAACAGAGGCTGGGGTGGGCACTCCAGGAGCCCTGGAGCGGAAGACCTCAGGGCTAGGACAGGAGCAAGAGGAAGGG TCAGAGGGCCAGGAGGCAGCCACTGGGAGTGGCGATGGGAGGCAGGAGACAGGAGCAGCTGAAAAATTCCGATTAGGATTATCACGGGAG GGAGAGAGGGAATTGAGTCCGGAGAGTCTACAGGCGATGGCAACACTTCCAGTGAAGCCTGATTTCACTGAAACCCGAGAGAAGCAACAG CATATGGTGCAAGGAGAAAGCGAGACTGCAGATGTTTCCCCCAACAACGTGCAGGTCTAGGAGACTTGCTGGCAGACAGATAATTTAAAG ATGTCTTCTGAAGATGTAAAGAGTGGAGAAAGATTCACGCAAGCATCTCACCAGGATTCTTGATTTTCTCTCTCTCCTCTTTAGTTGCTG GTTGCGCTTGTCTGAGATGATTCCCAATCTGTCAGCCCTGGTCAGTAGCTCAGTAAGCACCTTGAGAATAGCTCAAGTAGATCTGTAGGA CCCTTCTTAGAAGCAGTGGTTCCTCATGGAGAAACTTGTGAGGCTGTTACACATTCTACACACCTAACATTATTTTCAAACAAAAATGAT AATTTTCAGATGCTTGACTTTTACCAAAGATCACTGGAAGGCCCAGTCCTAATGTTAGGGGTTTGTTTAAAGTCCTTTTTATTTTACAAT ACAGAGCCCCAGTCAATTCCACAATCTCAATTTCATACATGGGAATTTTATTTAAAAATCTGTGGTTTGGGGCTTTAATGAATTGGCCTG TGAAAATGAGCTCTAAATTTCCTCCCACGTACACTCAAAACTCAAGATTGCTCCAAATCTCTAAGTTCTTCCAGCAAAAGATTTCTTGGC ATGTATATTCACTTATACTTAGAAATATTCATTCTTTTAATTTATGCCAGAATAACAAAGTGGAAATCTTATTTCAAAATGCTCTTTGTT TTTTTGTGTGTGTTTCTGTAGTTCTGCTTTCTGGGGTAGACTAGTAAAATGGTAGCTTCCAGCATTTTGTCCCTGGGGCCTTCTTTATAG GGCCACTCAAATTTAAATAAAAGTAGTAAATAATTTAGCTAAGTGGAATAAGTATAATAATTATAGTGGTAAGCATAGCACATCAGCATT ATGCCAACATTCTAGACTCTTTAGTTGATGTCATTAAATGGAAAAGAAACTTGGATTAAATGAGTGTGCTGCTCACCTTCCCAAGTTCTG TTATTTCAAACCTGTGAACTAACCTTGCAGTTCATTATAAATCAACAGTAACAACTGCATTCTAAATTACTCCCTGATATTATTTTCTAG TTGTGTATCAGCCTGTCTCCTAGGGGTTTTCATTTCCCTGAAGACATACAAGTGCCCCAGAGCGCATGTATATGTCTACCATTTCTCTAT ATGAGAAGGTAAAAAAAATTTCCTTAAGCAGTGATTTTCCAGCCAGAATATACATTAGATTTTCATGGGACGCTTTTATAAATGACTCAA CCCTTTTCCCCACCCCAGAGATTCAGACTTAATTCGTTTTAGATGGATCTACACATCAGTATATATATATTTTTAACTTTTCACTTGATT CTTCTCTGTAGCCAAGGTTGAGAACCGCTGTTCTAAATCATCATATAATCCATGCTGGCCACATTACACTCAAGGTCCCTAGGGACCAGG CATATTATCATAGTAGGTATTTTCCATTTTAATGTGTAATGGAGCCATTCAATGATCAAAAATACACTGGACCAGATAGTAGACTGGTCC CTTGATCAGAAGCATCAGCACATCAGCATCACCTGGAAATTGTTCCCAGCCTTTGTCTCCTACCTACTAAATTAGAAACTCTTGGTGGGT TCCAGTAATCCATAGCTTAACAAGCCCTGCAGTTAATACTGATGTACACTGATGTCCAAAAACTGCTGTCATGGACTATTGATTGTATTG AGGATTAGTCTCAGTTGGAAAGCCAACTACAGAGGCATTTTGAACTTTCTTTCTTTGCCTCTCTATGTCTCTCTGTCTTTTCCTGTCTTC TGATTTATCTGTCTTTCTTTCTCTAGTAAATGGCACTCAATATAAAAGTGGTGGAGTCAATCTTAAACTTATTTTTATTATGATTGTATT GATACATGCACGAAGTCCCTCTGCCCTACTCCCTATTCAAGGATATTACTCACTGCACATCATAAATCTCCATCATCTGTCTTAAAGTTT TATGAGTAGATTTCATCTACATTATATTCAAGTTCATTTATTACTGAGCTGTATTACTGTGGAGCTCTAACAGTATTTGTTTCCTGATTT CAAACTCAATGCTACAGAGCACTTTGAATACATCACACCTTATAGGAAAGATAGTAAATGTATTAATCCCATTGAAAAATTAGTTTTGTA CAATGTGCTAAATAGTATTGCATTGGATTACTTTTATATTTAACACACTCCATCAAAACATCCCATAACATAATTTTACAATCTGCATGT GAATTTAACTGTGAAATTCAGTATTGTGATATTTTGAATAAGTGAATTCTTTCTCTGCAAATACTATGTTGATAAAATTACTTGTATGTT >In-frame_ENST00000434200_ENST00000326665_TCGA-OL-A5RW-01A_NEGR1_chr1_72748002_-_C1orf173_chr1_75114999_length(amino acids)=1579AA_start in transcript=0_stop in transcript=4739 MMLLVQGACCSNQWLAAVLLSLCCLLPSCLPAGQSVDFPWAAVDNMMVRKGDTAVLRLLAAYNSLMDKHLAGYFNNTRIRRHLLRSGLIT RSGRILSEKEYKLNMMKRDHQKYIRECLAQAIFHKVLDMERYHQLEIKKKLETLARKERIQRFKGEHTRRSVENNMPILSPHPPVGPKSN RGHSVLVDEGHSSPLALTAPRPYTAPGNMQPPIRLQPLPSNPAVETVPKVTSRSRSKTSLLENEALFPIGGKKAVMKFRNSIGNSQRMNS YQLPNINSYMMPIPPPLPPTGKITRENRSETWRRRRFRPTTAPNGLEPLLTKDSRRIHKTSLHSNAAITMIYLGKNVHLSSDNPDFRDEI KVYQQHCGGENLCVYKGKLLEKETFQFISKRHHGFPFSLTFFLNGMQVNRLSSCCEYKHRKGSRLGGKRGYFGFVCVERSSPCYKCIIAM GLDKKPSLPKSRKEKSTEKGEELKKAEGKVRKEREYVIPKRNEIKENKTSVSAKFSAQEIKTGLKEVVTAVEEMTSKGKPGQEVLEDDQE NTLKYEYEEDFEVDEEKQGEKSNEEGQADVQMNGIPQSPLDDKKDNLDPEKESETSSQKAPDARDNVKDENDGCSESELEEDKQDMKTAS STSSRSHPYSSDSEDESAVGDREAHTDSSTDESARRSSSQELSENDKPRKSHLPIEESLEIEIEDQEITKADVETKPMPIDESFENVLKE GTEKGTQEIAEGLSEKSGKHVSAEEKEKDKSKLWEESTAQVKDKKAGLPGLEEGGKDSLPLAYVLALGAPTMNFMVDETAAINSNKESQQ LVQKTYTLEKKEAMEEDEAPQHRDADIVQGKGEAALWGEAGAVHEAPLRAWKPTAEQPELAEEFTEKREIPPGIERGAEGAAEAEGVRRL GEGGSDPIGQAAAKDAVGLSKDEAPEKQALMLTVLETDKAASEGEQGLEKAVLANEAAALNLEHLHEVAALREAATSEEGEAEGGVAVSD VGESEEEASIDLEDTGPMEDTASKREDGSEEAILGGEEPAKERKEVMRTETRLSPFTGEAEASRMQVSEGSPEEGSLAKEAFLCKEDVEG EEMVTEAEANREDDRKEILPKELDLARERRKAERPKTSLRKTDSEREEVTRANALKDEDAFKEEQKLKAEEGETETEVRAEEETKAPPNE MGSDAENEAPVEASELSDNPGLLGEDSLKETVVPIFEATPGFEKSLENITALRKEGGGERLSEARDTEHKDREELSSRENRALKEGHRQD GEGALAAPEAEPAGKVQAPEGLIPATGQAEELAAKDHDSCAGLEGRAEGQGGVDVVLRTQEAVAEEDPIMAEKFREEAVDEDPEEEEDKE CTLETEAMQDRNSEGDGDMEGEGNTQKNEGMGGGRVVAVEVLHGGGETAETAAEEREVLAGSETAEEKTIANKASSFSDVAEEETWHQQD ELVGKTAAAGKVVVEELARSGEEVPAAEEMTVTYTTEAGVGTPGALERKTSGLGQEQEEGSEGQEAATGSGDGRQETGAAEKFRLGLSRE -------------------------------------------------------------- |
Top |
Fusion Gene PPI Analysis for NEGR1-C1orf173 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
Top |
Related Drugs for NEGR1-C1orf173 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
Related Diseases for NEGR1-C1orf173 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | NEGR1 | C0028754 | Obesity | 1 | CTD_human |
Copyright 2021-Present -The University of Texas Health Science Center at Houston (UTHealth)
Web File Viewing | Emergency Information |Campus Carry|Site Policies