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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:NEO1-GALK2 (FusionGDB2 ID:58266)

Fusion Gene Summary for NEO1-GALK2

check button Fusion gene summary
Fusion gene informationFusion gene name: NEO1-GALK2
Fusion gene ID: 58266
HgeneTgene
Gene symbol

NEO1

GALK2

Gene ID

4756

2585

Gene nameneogenin 1galactokinase 2
SynonymsIGDCC2|NGN|NTN1R2GK2
Cytomap

15q24.1

15q21.1-q21.2

Type of geneprotein-codingprotein-coding
Descriptionneogeninimmunoglobulin superfamily DCC subclass member 2neogenin homolog 1N-acetylgalactosamine kinasegalNAc kinase
Modification date2020031320200313
UniProtAcc

Q92859

Q01415

Ensembl transtripts involved in fusion geneENST00000339362, ENST00000261908, 
ENST00000558964, ENST00000560262, 
ENST00000560352, 		ENST00000327171, 
ENST00000560031, ENST00000396509, 
ENST00000543495, ENST00000544523, 
ENST00000559454, ENST00000561014, 
Fusion gene scores* DoF score14 X 7 X 7=6869 X 8 X 5=360
# samples 1510
** MAII scorelog2(15/686*10)=-2.19324607567693
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(10/360*10)=-1.84799690655495
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: NEO1 [Title/Abstract] AND GALK2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointNEO1(73470768)-GALK2(49620149), # samples:1
Anticipated loss of major functional domain due to fusion event.NEO1-GALK2 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
NEO1-GALK2 seems lost the major protein functional domain in Tgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across NEO1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across GALK2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-BR-A4J5-01ANEO1chr15

73470768

+GALK2chr15

49620149

+


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Fusion Gene ORF analysis for NEO1-GALK2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000339362ENST00000327171NEO1chr15

73470768

+GALK2chr15

49620149

+
In-frameENST00000339362ENST00000560031NEO1chr15

73470768

+GALK2chr15

49620149

+
Frame-shiftENST00000339362ENST00000396509NEO1chr15

73470768

+GALK2chr15

49620149

+
5CDS-3UTRENST00000339362ENST00000543495NEO1chr15

73470768

+GALK2chr15

49620149

+
5CDS-3UTRENST00000339362ENST00000544523NEO1chr15

73470768

+GALK2chr15

49620149

+
5CDS-3UTRENST00000339362ENST00000559454NEO1chr15

73470768

+GALK2chr15

49620149

+
5CDS-intronENST00000339362ENST00000561014NEO1chr15

73470768

+GALK2chr15

49620149

+
In-frameENST00000261908ENST00000327171NEO1chr15

73470768

+GALK2chr15

49620149

+
In-frameENST00000261908ENST00000560031NEO1chr15

73470768

+GALK2chr15

49620149

+
Frame-shiftENST00000261908ENST00000396509NEO1chr15

73470768

+GALK2chr15

49620149

+
5CDS-3UTRENST00000261908ENST00000543495NEO1chr15

73470768

+GALK2chr15

49620149

+
5CDS-3UTRENST00000261908ENST00000544523NEO1chr15

73470768

+GALK2chr15

49620149

+
5CDS-3UTRENST00000261908ENST00000559454NEO1chr15

73470768

+GALK2chr15

49620149

+
5CDS-intronENST00000261908ENST00000561014NEO1chr15

73470768

+GALK2chr15

49620149

+
In-frameENST00000558964ENST00000327171NEO1chr15

73470768

+GALK2chr15

49620149

+
In-frameENST00000558964ENST00000560031NEO1chr15

73470768

+GALK2chr15

49620149

+
Frame-shiftENST00000558964ENST00000396509NEO1chr15

73470768

+GALK2chr15

49620149

+
5CDS-3UTRENST00000558964ENST00000543495NEO1chr15

73470768

+GALK2chr15

49620149

+
5CDS-3UTRENST00000558964ENST00000544523NEO1chr15

73470768

+GALK2chr15

49620149

+
5CDS-3UTRENST00000558964ENST00000559454NEO1chr15

73470768

+GALK2chr15

49620149

+
5CDS-intronENST00000558964ENST00000561014NEO1chr15

73470768

+GALK2chr15

49620149

+
In-frameENST00000560262ENST00000327171NEO1chr15

73470768

+GALK2chr15

49620149

+
In-frameENST00000560262ENST00000560031NEO1chr15

73470768

+GALK2chr15

49620149

+
Frame-shiftENST00000560262ENST00000396509NEO1chr15

73470768

+GALK2chr15

49620149

+
5CDS-3UTRENST00000560262ENST00000543495NEO1chr15

73470768

+GALK2chr15

49620149

+
5CDS-3UTRENST00000560262ENST00000544523NEO1chr15

73470768

+GALK2chr15

49620149

+
5CDS-3UTRENST00000560262ENST00000559454NEO1chr15

73470768

+GALK2chr15

49620149

+
5CDS-intronENST00000560262ENST00000561014NEO1chr15

73470768

+GALK2chr15

49620149

+
intron-3CDSENST00000560352ENST00000327171NEO1chr15

73470768

+GALK2chr15

49620149

+
intron-3CDSENST00000560352ENST00000560031NEO1chr15

73470768

+GALK2chr15

49620149

+
intron-3CDSENST00000560352ENST00000396509NEO1chr15

73470768

+GALK2chr15

49620149

+
intron-3UTRENST00000560352ENST00000543495NEO1chr15

73470768

+GALK2chr15

49620149

+
intron-3UTRENST00000560352ENST00000544523NEO1chr15

73470768

+GALK2chr15

49620149

+
intron-3UTRENST00000560352ENST00000559454NEO1chr15

73470768

+GALK2chr15

49620149

+
intron-intronENST00000560352ENST00000561014NEO1chr15

73470768

+GALK2chr15

49620149

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000339362NEO1chr1573470768+ENST00000327171GALK2chr1549620149+359217382671832521
ENST00000339362NEO1chr1573470768+ENST00000560031GALK2chr1549620149+230517382671832521
ENST00000261908NEO1chr1573470768+ENST00000327171GALK2chr1549620149+33371483121577521
ENST00000261908NEO1chr1573470768+ENST00000560031GALK2chr1549620149+20501483121577521
ENST00000558964NEO1chr1573470768+ENST00000327171GALK2chr1549620149+32111357301451473
ENST00000558964NEO1chr1573470768+ENST00000560031GALK2chr1549620149+19241357301451473
ENST00000560262NEO1chr1573470768+ENST00000327171GALK2chr1549620149+32111357301451473
ENST00000560262NEO1chr1573470768+ENST00000560031GALK2chr1549620149+19241357301451473

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000339362ENST00000327171NEO1chr1573470768+GALK2chr1549620149+0.000303510.9996965
ENST00000339362ENST00000560031NEO1chr1573470768+GALK2chr1549620149+0.0010252770.9989748
ENST00000261908ENST00000327171NEO1chr1573470768+GALK2chr1549620149+0.0002527740.9997472
ENST00000261908ENST00000560031NEO1chr1573470768+GALK2chr1549620149+0.0008842330.99911577
ENST00000558964ENST00000327171NEO1chr1573470768+GALK2chr1549620149+0.0002248190.99977523
ENST00000558964ENST00000560031NEO1chr1573470768+GALK2chr1549620149+0.0007407730.9992592
ENST00000560262ENST00000327171NEO1chr1573470768+GALK2chr1549620149+0.0002248190.99977523
ENST00000560262ENST00000560031NEO1chr1573470768+GALK2chr1549620149+0.0007407730.9992592

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Fusion Genomic Features for NEO1-GALK2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
NEO1chr1573470768+GALK2chr1549620148+0.0006734550.9993266
NEO1chr1573470768+GALK2chr1549620148+0.0006734550.9993266

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for NEO1-GALK2


check button Go to

FGviewer for the breakpoints of chr15:73470768-chr15:49620149

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
NEO1

Q92859

GALK2

Q01415

FUNCTION: Multi-functional cell surface receptor regulating cell adhesion in many diverse developmental processes, including neural tube and mammary gland formation, myogenesis and angiogenesis. Receptor for members of the BMP, netrin, and repulsive guidance molecule (RGM) families. Netrin-Neogenin interactions result in a chemoattractive axon guidance response and cell-cell adhesion, the interaction between NEO1/Neogenin and RGMa and RGMb induces a chemorepulsive response. {ECO:0000269|PubMed:21149453}.FUNCTION: Acts on GalNAc. Also acts as a galactokinase when galactose is present at high concentrations. May be involved in a salvage pathway for the reutilization of free GalNAc derived from the degradation of complex carbohydrates. {ECO:0000269|PubMed:16006554}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNEO1chr15:73470768chr15:49620149ENST00000261908+729152_238430.33333333333331462.0DomainNote=Ig-like C2-type 2
HgeneNEO1chr15:73470768chr15:49620149ENST00000261908+729243_336430.33333333333331462.0DomainNote=Ig-like C2-type 3
HgeneNEO1chr15:73470768chr15:49620149ENST00000261908+729341_426430.33333333333331462.0DomainNote=Ig-like C2-type 4
HgeneNEO1chr15:73470768chr15:49620149ENST00000261908+72952_141430.33333333333331462.0DomainNote=Ig-like C2-type 1
HgeneNEO1chr15:73470768chr15:49620149ENST00000339362+830152_238430.33333333333331462.0DomainNote=Ig-like C2-type 2
HgeneNEO1chr15:73470768chr15:49620149ENST00000339362+830243_336430.33333333333331462.0DomainNote=Ig-like C2-type 3
HgeneNEO1chr15:73470768chr15:49620149ENST00000339362+830341_426430.33333333333331462.0DomainNote=Ig-like C2-type 4
HgeneNEO1chr15:73470768chr15:49620149ENST00000339362+83052_141430.33333333333331462.0DomainNote=Ig-like C2-type 1
HgeneNEO1chr15:73470768chr15:49620149ENST00000558964+728152_238430.33333333333331451.0DomainNote=Ig-like C2-type 2
HgeneNEO1chr15:73470768chr15:49620149ENST00000558964+728243_336430.33333333333331451.0DomainNote=Ig-like C2-type 3
HgeneNEO1chr15:73470768chr15:49620149ENST00000558964+728341_426430.33333333333331451.0DomainNote=Ig-like C2-type 4
HgeneNEO1chr15:73470768chr15:49620149ENST00000558964+72852_141430.33333333333331451.0DomainNote=Ig-like C2-type 1
HgeneNEO1chr15:73470768chr15:49620149ENST00000560262+728152_238430.33333333333331409.0DomainNote=Ig-like C2-type 2
HgeneNEO1chr15:73470768chr15:49620149ENST00000560262+728243_336430.33333333333331409.0DomainNote=Ig-like C2-type 3
HgeneNEO1chr15:73470768chr15:49620149ENST00000560262+728341_426430.33333333333331409.0DomainNote=Ig-like C2-type 4
HgeneNEO1chr15:73470768chr15:49620149ENST00000560262+72852_141430.33333333333331409.0DomainNote=Ig-like C2-type 1

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNEO1chr15:73470768chr15:49620149ENST00000261908+7291118_1121430.33333333333331462.0Compositional biasNote=Poly-Val
HgeneNEO1chr15:73470768chr15:49620149ENST00000339362+8301118_1121430.33333333333331462.0Compositional biasNote=Poly-Val
HgeneNEO1chr15:73470768chr15:49620149ENST00000558964+7281118_1121430.33333333333331451.0Compositional biasNote=Poly-Val
HgeneNEO1chr15:73470768chr15:49620149ENST00000560262+7281118_1121430.33333333333331409.0Compositional biasNote=Poly-Val
HgeneNEO1chr15:73470768chr15:49620149ENST00000261908+729441_535430.33333333333331462.0DomainFibronectin type-III 1
HgeneNEO1chr15:73470768chr15:49620149ENST00000261908+729541_631430.33333333333331462.0DomainFibronectin type-III 2
HgeneNEO1chr15:73470768chr15:49620149ENST00000261908+729636_731430.33333333333331462.0DomainFibronectin type-III 3
HgeneNEO1chr15:73470768chr15:49620149ENST00000261908+729741_831430.33333333333331462.0DomainFibronectin type-III 4
HgeneNEO1chr15:73470768chr15:49620149ENST00000261908+729856_952430.33333333333331462.0DomainFibronectin type-III 5
HgeneNEO1chr15:73470768chr15:49620149ENST00000261908+729957_1054430.33333333333331462.0DomainFibronectin type-III 6
HgeneNEO1chr15:73470768chr15:49620149ENST00000339362+830441_535430.33333333333331462.0DomainFibronectin type-III 1
HgeneNEO1chr15:73470768chr15:49620149ENST00000339362+830541_631430.33333333333331462.0DomainFibronectin type-III 2
HgeneNEO1chr15:73470768chr15:49620149ENST00000339362+830636_731430.33333333333331462.0DomainFibronectin type-III 3
HgeneNEO1chr15:73470768chr15:49620149ENST00000339362+830741_831430.33333333333331462.0DomainFibronectin type-III 4
HgeneNEO1chr15:73470768chr15:49620149ENST00000339362+830856_952430.33333333333331462.0DomainFibronectin type-III 5
HgeneNEO1chr15:73470768chr15:49620149ENST00000339362+830957_1054430.33333333333331462.0DomainFibronectin type-III 6
HgeneNEO1chr15:73470768chr15:49620149ENST00000558964+728441_535430.33333333333331451.0DomainFibronectin type-III 1
HgeneNEO1chr15:73470768chr15:49620149ENST00000558964+728541_631430.33333333333331451.0DomainFibronectin type-III 2
HgeneNEO1chr15:73470768chr15:49620149ENST00000558964+728636_731430.33333333333331451.0DomainFibronectin type-III 3
HgeneNEO1chr15:73470768chr15:49620149ENST00000558964+728741_831430.33333333333331451.0DomainFibronectin type-III 4
HgeneNEO1chr15:73470768chr15:49620149ENST00000558964+728856_952430.33333333333331451.0DomainFibronectin type-III 5
HgeneNEO1chr15:73470768chr15:49620149ENST00000558964+728957_1054430.33333333333331451.0DomainFibronectin type-III 6
HgeneNEO1chr15:73470768chr15:49620149ENST00000560262+728441_535430.33333333333331409.0DomainFibronectin type-III 1
HgeneNEO1chr15:73470768chr15:49620149ENST00000560262+728541_631430.33333333333331409.0DomainFibronectin type-III 2
HgeneNEO1chr15:73470768chr15:49620149ENST00000560262+728636_731430.33333333333331409.0DomainFibronectin type-III 3
HgeneNEO1chr15:73470768chr15:49620149ENST00000560262+728741_831430.33333333333331409.0DomainFibronectin type-III 4
HgeneNEO1chr15:73470768chr15:49620149ENST00000560262+728856_952430.33333333333331409.0DomainFibronectin type-III 5
HgeneNEO1chr15:73470768chr15:49620149ENST00000560262+728957_1054430.33333333333331409.0DomainFibronectin type-III 6
HgeneNEO1chr15:73470768chr15:49620149ENST00000261908+7291127_1461430.33333333333331462.0Topological domainCytoplasmic
HgeneNEO1chr15:73470768chr15:49620149ENST00000261908+72934_1105430.33333333333331462.0Topological domainExtracellular
HgeneNEO1chr15:73470768chr15:49620149ENST00000339362+8301127_1461430.33333333333331462.0Topological domainCytoplasmic
HgeneNEO1chr15:73470768chr15:49620149ENST00000339362+83034_1105430.33333333333331462.0Topological domainExtracellular
HgeneNEO1chr15:73470768chr15:49620149ENST00000558964+7281127_1461430.33333333333331451.0Topological domainCytoplasmic
HgeneNEO1chr15:73470768chr15:49620149ENST00000558964+72834_1105430.33333333333331451.0Topological domainExtracellular
HgeneNEO1chr15:73470768chr15:49620149ENST00000560262+7281127_1461430.33333333333331409.0Topological domainCytoplasmic
HgeneNEO1chr15:73470768chr15:49620149ENST00000560262+72834_1105430.33333333333331409.0Topological domainExtracellular
HgeneNEO1chr15:73470768chr15:49620149ENST00000261908+7291106_1126430.33333333333331462.0TransmembraneHelical
HgeneNEO1chr15:73470768chr15:49620149ENST00000339362+8301106_1126430.33333333333331462.0TransmembraneHelical
HgeneNEO1chr15:73470768chr15:49620149ENST00000558964+7281106_1126430.33333333333331451.0TransmembraneHelical
HgeneNEO1chr15:73470768chr15:49620149ENST00000560262+7281106_1126430.33333333333331409.0TransmembraneHelical
TgeneGALK2chr15:73470768chr15:49620149ENST00000327171810139_149378.6666666666667448.0Nucleotide bindingATP
TgeneGALK2chr15:73470768chr15:49620149ENST00000560031810139_149389.6666666666667459.0Nucleotide bindingATP
TgeneGALK2chr15:73470768chr15:49620149ENST00000327171810187_190378.6666666666667448.0RegionNote=Substrate binding
TgeneGALK2chr15:73470768chr15:49620149ENST0000032717181049_52378.6666666666667448.0RegionNote=Substrate binding
TgeneGALK2chr15:73470768chr15:49620149ENST00000560031810187_190389.6666666666667459.0RegionNote=Substrate binding
TgeneGALK2chr15:73470768chr15:49620149ENST0000056003181049_52389.6666666666667459.0RegionNote=Substrate binding


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Fusion Gene Sequence for NEO1-GALK2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000339362_ENST00000327171_TCGA-BR-A4J5-01A_NEO1_chr15_73470768_+_GALK2_chr15_49620149_length(transcript)=3592nt_BP=1738nt
GGTCAGCGGCTGCGCGGCCGGCCCCCTCCCACGGGAGCCGCGCCAGGGCCCAGCAAGAGTCGGGCGGGATCGCTATTGTTTTTGGCGAGC
ACATAAATCCCCGGGCCGACCCACTGCGCACCCAGGTTTCCTCCCGGAGGCCTTTCGGTTTCCTCTGAGGCCCTATATAGAGGCTCCAGG
CCCGGACTGTGCAGAGGTGCGCGCCCACGCCGGCCTCCCGGACCAGCCTGAGCTCGGAGCGCCTCTCGCCCTCAGGAGGGAGGCGCCCTG
GAGTCTCCCCTCCAGCGAGAGGGGCTGCGCGGGCCGGGCCGGGCCGGGCTGGGCTGGAGCAGCGGCGGCCGCGGGAGCCGAGCTTGCAGC
GAGGGACCGGCTGAGGCGCGCGGGAGGGAAGGAGGCAAGGGCTCCGCGGCGCTGTCGCCGCCGCTGCCGCTCACTCTCGGGGAAGAGATG
GCGGCGGAGCGGGGAGCCCGGCGACTCCTCAGCACCCCCTCCTTCTGGCTCTACTGCCTGCTGCTGCTCGGGCGCCGGGCGCCGGGCGCC
GCGGCCGCCAGGAGCGGCTCCGCGCCGCAGTCCCCAGGAGCCAGCATTCGAACGTTCACTCCATTTTATTTTCTGGTGGAGCCGGTGGAT
ACACTCTCAGTTAGAGGCTCTTCTGTTATATTAAACTGTTCAGCATATTCTGAGCCTTCTCCAAAAATTGAATGGAAAAAAGATGGAACT
TTTTTAAACTTAGTATCAGATGATCGACGCCAGCTTCTCCCGGATGGATCTTTATTTATCAGCAATGTGGTGCATTCCAAACACAATAAA
CCTGATGAAGGTTATTATCAGTGTGTGGCCACTGTTGAGAGTCTTGGAACTATTATCAGTAGAACAGCGAAGCTCATAGTAGCAGGTCTT
CCAAGATTTACCAGCCAACCAGAACCTTCCTCAGTTTATGCTGGGAACAATGCAATTCTGAATTGTGAAGTTAATGCAGATTTGGTCCCA
TTTGTGAGGTGGGAACAGAACAGACAACCCCTTCTTCTGGATGATAGAGTTATCAAACTTCCAAGTGGAATGCTGGTTATCAGCAATGCA
ACTGAAGGAGATGGCGGGCTTTATCGCTGCGTAGTGGAAAGTGGTGGGCCACCAAAGTATAGTGATGAAGTTGAATTGAAGGTTCTTCCA
GATCCTGAGGTGATATCAGACTTGGTATTTTTGAAACAGCCTTCTCCCTTAGTCAGAGTCATTGGTCAGGATGTAGTGTTGCCATGTGTT
GCTTCAGGACTTCCTACTCCAACCATTAAATGGATGAAAAATGAGGAGGCACTTGACACAGAAAGCTCTGAAAGATTGGTATTGCTGGCA
GGTGGTAGCCTGGAGATCAGTGATGTTACTGAGGATGATGCTGGGACTTATTTTTGTATAGCTGATAATGGAAATGAGACAATTGAAGCT
CAAGCAGAGCTTACAGTGCAAGCTCAACCTGAATTCCTGAAGCAGCCTACTAATATATATGCTCACGAATCTATGGATATTGTATTTGAA
TGTGAAGTGACTGGAAAACCAACTCCAACTGTGAAGTGGGTCAAAAATGGGGATATGGTTATCCCAAGTGATTATTTTAAGATTGTAAAG
GAACATAATCTTCAAGTTTTGGGTCTGGTGAAATCAGATGAAGGGTTCTATCAGTGCATTGCTGAAAATGATGTTGGAAATGCACAAGCT
GGAGCCCAACTGATAATCCTTGAACATGGAAGTTTGGGGCTCAAGGGTCACGACTTACTGGAGCAGGATGGGGAGGCTGCACAGTATCAA
TGGTACCTGCGGACAAGCTGCCCAGCTTTCTAGCAAATGTGCACAAAGCTTATTACCAGAGGAGTGATGGAAGCTTAGCACCGGAGAAGC
AAAGTTTGTTTGCTACCAAACCTGGAGGTGGGGCTTTGGTTTTGCTTGAGGCCTGAAAAAATGTAAAAAGTCTGAGAGAAACTACTTAGG
GCACTTAGGAATTGGCAGGACTTTCTGTGCCACAGTAAATTAATCTTCCTTCTGTTTTGTATTATGATGAACGGTTGCTATTATATCAAG
ATATATTTTCAAAGAAATGGTTGAAAGCTCTCTATGCTTCATAATGATTCTTTTTCCATCTTAAAATATGGTTTTACTATTAAGAGCCAA
GATCATGCTTGGACAGATCTTTTAAGAATAACTTACTGAGATTTATTGATTTGAAGATTTTAAAGATGAATGGTAAAACACACTCTTAAT
ACTGATTACATGGATTGGACTTGAATTAAATATATTGTTACAATTAAACTGATACCACTGAATTGTATGCATTATTCTTGAATAGAGTTC
ATTTCTGGTTTCTCTTAGTATTCTTCTTCCTCAAAGTTGTAGTTGTCTGTTGATGATGGTGATGATGATGATGATGACGATAGTGATGCC
ACACATTCTCTCTCAATTTCAGCTTCGGAACGCTATGAAAATAATACATGATTAAAGTTTCACAGATCTTCTTGGACATTGTATAATTGA
ATTTGAATGTGAGATTTCTCCAGTTATCAAGAGACTAAGGATTTTTTTTTTTTTTTGACAAAAGGAGGATACAGGAAGAAAATTCAGACT
CATTTGAATATTTGTAAACCATGTAATATATAAATAACCACTTTCAATTCTTTTGGCCCTGAGCTATCTCCATTACTTAATAGAAAAACT
TAGATAAAAAACACTTTAAGACTCTTCTATTCACATTGAAATAAAGAATTATCTAGATGATAATTCAGATAATTCAGTTTGTTCATAGAA
TTACTTTCTTATCACTCTTTTTCTACTACTTTTTCTCAAATACCTCTCTAATCCAAGAGGCACTTCCAAGAAATTCCACACATTCCTTAT
ATCCCTTTTTTGCTTGTCTAGCAAAGCTTGTTTGTATATATGCACCCCATTGTAAAGCAGGTATGCAGGTATGTGGGTGAAAGTGACTAT
GAAAAGACTTAATGAATTCTGGGATTTGTAATGGTATTGATGGGTATCTCTGTATGTATATCAAGAGTGGGCAGAAATGTTTGGCTGGTG
ATGGCAAATGACTGGCTTTCTCTTGTGGATGGACTATAGGAAGCACTTTCTGAATTATGTAATGATTTGGACCAAAAAGTATTTTGCTGA
AATACTCAGGTAATTGAGATAGCAATGGTTTTATGGCATGAATTATCCAAAAAAATATCAGAATTACTTATTATTCTGTGATTTCATTAG
CTCATTAATGTTTAACTCACAGATTGGGCATCACCATCTAGAATTTCAGTTTAAGGGAGGCCTGCGCAAAGCTAGTTTTATTTCTTAAAG
GATAACAGTCATACATAGAATACTAGGAAAGCCAATATTCTATTTAAAAATAAACTTCTGATGCATTTTCATTCTTAGCAGAAAGGTAAA
TGCTTGAGAAAGCTTGAGTCAAATTTGTTAAAAGAATTTTGAGTTCTATAAATCCAAAAATCTGAAACCTGAATTTATTTAAATTTATAA

>In-frame_ENST00000339362_ENST00000327171_TCGA-BR-A4J5-01A_NEO1_chr15_73470768_+_GALK2_chr15_49620149_length(amino acids)=521AA_start in transcript=267_stop in transcript=1832
MESPLQREGLRGPGRAGLGWSSGGRGSRACSEGPAEARGREGGKGSAALSPPLPLTLGEEMAAERGARRLLSTPSFWLYCLLLLGRRAPG
AAAARSGSAPQSPGASIRTFTPFYFLVEPVDTLSVRGSSVILNCSAYSEPSPKIEWKKDGTFLNLVSDDRRQLLPDGSLFISNVVHSKHN
KPDEGYYQCVATVESLGTIISRTAKLIVAGLPRFTSQPEPSSVYAGNNAILNCEVNADLVPFVRWEQNRQPLLLDDRVIKLPSGMLVISN
ATEGDGGLYRCVVESGGPPKYSDEVELKVLPDPEVISDLVFLKQPSPLVRVIGQDVVLPCVASGLPTPTIKWMKNEEALDTESSERLVLL
AGGSLEISDVTEDDAGTYFCIADNGNETIEAQAELTVQAQPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYFKIV

--------------------------------------------------------------
>In-frame_ENST00000339362_ENST00000560031_TCGA-BR-A4J5-01A_NEO1_chr15_73470768_+_GALK2_chr15_49620149_length(transcript)=2305nt_BP=1738nt
GGTCAGCGGCTGCGCGGCCGGCCCCCTCCCACGGGAGCCGCGCCAGGGCCCAGCAAGAGTCGGGCGGGATCGCTATTGTTTTTGGCGAGC
ACATAAATCCCCGGGCCGACCCACTGCGCACCCAGGTTTCCTCCCGGAGGCCTTTCGGTTTCCTCTGAGGCCCTATATAGAGGCTCCAGG
CCCGGACTGTGCAGAGGTGCGCGCCCACGCCGGCCTCCCGGACCAGCCTGAGCTCGGAGCGCCTCTCGCCCTCAGGAGGGAGGCGCCCTG
GAGTCTCCCCTCCAGCGAGAGGGGCTGCGCGGGCCGGGCCGGGCCGGGCTGGGCTGGAGCAGCGGCGGCCGCGGGAGCCGAGCTTGCAGC
GAGGGACCGGCTGAGGCGCGCGGGAGGGAAGGAGGCAAGGGCTCCGCGGCGCTGTCGCCGCCGCTGCCGCTCACTCTCGGGGAAGAGATG
GCGGCGGAGCGGGGAGCCCGGCGACTCCTCAGCACCCCCTCCTTCTGGCTCTACTGCCTGCTGCTGCTCGGGCGCCGGGCGCCGGGCGCC
GCGGCCGCCAGGAGCGGCTCCGCGCCGCAGTCCCCAGGAGCCAGCATTCGAACGTTCACTCCATTTTATTTTCTGGTGGAGCCGGTGGAT
ACACTCTCAGTTAGAGGCTCTTCTGTTATATTAAACTGTTCAGCATATTCTGAGCCTTCTCCAAAAATTGAATGGAAAAAAGATGGAACT
TTTTTAAACTTAGTATCAGATGATCGACGCCAGCTTCTCCCGGATGGATCTTTATTTATCAGCAATGTGGTGCATTCCAAACACAATAAA
CCTGATGAAGGTTATTATCAGTGTGTGGCCACTGTTGAGAGTCTTGGAACTATTATCAGTAGAACAGCGAAGCTCATAGTAGCAGGTCTT
CCAAGATTTACCAGCCAACCAGAACCTTCCTCAGTTTATGCTGGGAACAATGCAATTCTGAATTGTGAAGTTAATGCAGATTTGGTCCCA
TTTGTGAGGTGGGAACAGAACAGACAACCCCTTCTTCTGGATGATAGAGTTATCAAACTTCCAAGTGGAATGCTGGTTATCAGCAATGCA
ACTGAAGGAGATGGCGGGCTTTATCGCTGCGTAGTGGAAAGTGGTGGGCCACCAAAGTATAGTGATGAAGTTGAATTGAAGGTTCTTCCA
GATCCTGAGGTGATATCAGACTTGGTATTTTTGAAACAGCCTTCTCCCTTAGTCAGAGTCATTGGTCAGGATGTAGTGTTGCCATGTGTT
GCTTCAGGACTTCCTACTCCAACCATTAAATGGATGAAAAATGAGGAGGCACTTGACACAGAAAGCTCTGAAAGATTGGTATTGCTGGCA
GGTGGTAGCCTGGAGATCAGTGATGTTACTGAGGATGATGCTGGGACTTATTTTTGTATAGCTGATAATGGAAATGAGACAATTGAAGCT
CAAGCAGAGCTTACAGTGCAAGCTCAACCTGAATTCCTGAAGCAGCCTACTAATATATATGCTCACGAATCTATGGATATTGTATTTGAA
TGTGAAGTGACTGGAAAACCAACTCCAACTGTGAAGTGGGTCAAAAATGGGGATATGGTTATCCCAAGTGATTATTTTAAGATTGTAAAG
GAACATAATCTTCAAGTTTTGGGTCTGGTGAAATCAGATGAAGGGTTCTATCAGTGCATTGCTGAAAATGATGTTGGAAATGCACAAGCT
GGAGCCCAACTGATAATCCTTGAACATGGAAGTTTGGGGCTCAAGGGTCACGACTTACTGGAGCAGGATGGGGAGGCTGCACAGTATCAA
TGGTACCTGCGGACAAGCTGCCCAGCTTTCTAGCAAATGTGCACAAAGCTTATTACCAGAGGAGTGATGGAAGCTTAGCACCGGAGAAGC
AAAGTTTGTTTGCTACCAAACCTGGAGGTGGGGCTTTGGTTTTGCTTGAGGCCTGAAAAAATGTAAAAAGTCTGAGAGAAACTACTTAGG
GCACTTAGGAATTGGCAGGACTTTCTGTGCCACAGTAAATTAATCTTCCTTCTGTTTTGTATTATGATGAACGGTTGCTATTATATCAAG
ATATATTTTCAAAGAAATGGTTGAAAGCTCTCTATGCTTCATAATGATTCTTTTTCCATCTTAAAATATGGTTTTACTATTAAGAGCCAA
GATCATGCTTGGACAGATCTTTTAAGAATAACTTACTGAGATTTATTGATTTGAAGATTTTAAAGATGAATGGTAAAACACACTCTTAAT

>In-frame_ENST00000339362_ENST00000560031_TCGA-BR-A4J5-01A_NEO1_chr15_73470768_+_GALK2_chr15_49620149_length(amino acids)=521AA_start in transcript=267_stop in transcript=1832
MESPLQREGLRGPGRAGLGWSSGGRGSRACSEGPAEARGREGGKGSAALSPPLPLTLGEEMAAERGARRLLSTPSFWLYCLLLLGRRAPG
AAAARSGSAPQSPGASIRTFTPFYFLVEPVDTLSVRGSSVILNCSAYSEPSPKIEWKKDGTFLNLVSDDRRQLLPDGSLFISNVVHSKHN
KPDEGYYQCVATVESLGTIISRTAKLIVAGLPRFTSQPEPSSVYAGNNAILNCEVNADLVPFVRWEQNRQPLLLDDRVIKLPSGMLVISN
ATEGDGGLYRCVVESGGPPKYSDEVELKVLPDPEVISDLVFLKQPSPLVRVIGQDVVLPCVASGLPTPTIKWMKNEEALDTESSERLVLL
AGGSLEISDVTEDDAGTYFCIADNGNETIEAQAELTVQAQPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYFKIV

--------------------------------------------------------------
>In-frame_ENST00000261908_ENST00000327171_TCGA-BR-A4J5-01A_NEO1_chr15_73470768_+_GALK2_chr15_49620149_length(transcript)=3337nt_BP=1483nt
GAGGGAGGCGCCCTGGAGTCTCCCCTCCAGCGAGAGGGGCTGCGCGGGCCGGGCCGGGCCGGGCTGGGCTGGAGCAGCGGCGGCCGCGGG
AGCCGAGCTTGCAGCGAGGGACCGGCTGAGGCGCGCGGGAGGGAAGGAGGCAAGGGCTCCGCGGCGCTGTCGCCGCCGCTGCCGCTCACT
CTCGGGGAAGAGATGGCGGCGGAGCGGGGAGCCCGGCGACTCCTCAGCACCCCCTCCTTCTGGCTCTACTGCCTGCTGCTGCTCGGGCGC
CGGGCGCCGGGCGCCGCGGCCGCCAGGAGCGGCTCCGCGCCGCAGTCCCCAGGAGCCAGCATTCGAACGTTCACTCCATTTTATTTTCTG
GTGGAGCCGGTGGATACACTCTCAGTTAGAGGCTCTTCTGTTATATTAAACTGTTCAGCATATTCTGAGCCTTCTCCAAAAATTGAATGG
AAAAAAGATGGAACTTTTTTAAACTTAGTATCAGATGATCGACGCCAGCTTCTCCCGGATGGATCTTTATTTATCAGCAATGTGGTGCAT
TCCAAACACAATAAACCTGATGAAGGTTATTATCAGTGTGTGGCCACTGTTGAGAGTCTTGGAACTATTATCAGTAGAACAGCGAAGCTC
ATAGTAGCAGGTCTTCCAAGATTTACCAGCCAACCAGAACCTTCCTCAGTTTATGCTGGGAACAATGCAATTCTGAATTGTGAAGTTAAT
GCAGATTTGGTCCCATTTGTGAGGTGGGAACAGAACAGACAACCCCTTCTTCTGGATGATAGAGTTATCAAACTTCCAAGTGGAATGCTG
GTTATCAGCAATGCAACTGAAGGAGATGGCGGGCTTTATCGCTGCGTAGTGGAAAGTGGTGGGCCACCAAAGTATAGTGATGAAGTTGAA
TTGAAGGTTCTTCCAGATCCTGAGGTGATATCAGACTTGGTATTTTTGAAACAGCCTTCTCCCTTAGTCAGAGTCATTGGTCAGGATGTA
GTGTTGCCATGTGTTGCTTCAGGACTTCCTACTCCAACCATTAAATGGATGAAAAATGAGGAGGCACTTGACACAGAAAGCTCTGAAAGA
TTGGTATTGCTGGCAGGTGGTAGCCTGGAGATCAGTGATGTTACTGAGGATGATGCTGGGACTTATTTTTGTATAGCTGATAATGGAAAT
GAGACAATTGAAGCTCAAGCAGAGCTTACAGTGCAAGCTCAACCTGAATTCCTGAAGCAGCCTACTAATATATATGCTCACGAATCTATG
GATATTGTATTTGAATGTGAAGTGACTGGAAAACCAACTCCAACTGTGAAGTGGGTCAAAAATGGGGATATGGTTATCCCAAGTGATTAT
TTTAAGATTGTAAAGGAACATAATCTTCAAGTTTTGGGTCTGGTGAAATCAGATGAAGGGTTCTATCAGTGCATTGCTGAAAATGATGTT
GGAAATGCACAAGCTGGAGCCCAACTGATAATCCTTGAACATGGAAGTTTGGGGCTCAAGGGTCACGACTTACTGGAGCAGGATGGGGAG
GCTGCACAGTATCAATGGTACCTGCGGACAAGCTGCCCAGCTTTCTAGCAAATGTGCACAAAGCTTATTACCAGAGGAGTGATGGAAGCT
TAGCACCGGAGAAGCAAAGTTTGTTTGCTACCAAACCTGGAGGTGGGGCTTTGGTTTTGCTTGAGGCCTGAAAAAATGTAAAAAGTCTGA
GAGAAACTACTTAGGGCACTTAGGAATTGGCAGGACTTTCTGTGCCACAGTAAATTAATCTTCCTTCTGTTTTGTATTATGATGAACGGT
TGCTATTATATCAAGATATATTTTCAAAGAAATGGTTGAAAGCTCTCTATGCTTCATAATGATTCTTTTTCCATCTTAAAATATGGTTTT
ACTATTAAGAGCCAAGATCATGCTTGGACAGATCTTTTAAGAATAACTTACTGAGATTTATTGATTTGAAGATTTTAAAGATGAATGGTA
AAACACACTCTTAATACTGATTACATGGATTGGACTTGAATTAAATATATTGTTACAATTAAACTGATACCACTGAATTGTATGCATTAT
TCTTGAATAGAGTTCATTTCTGGTTTCTCTTAGTATTCTTCTTCCTCAAAGTTGTAGTTGTCTGTTGATGATGGTGATGATGATGATGAT
GACGATAGTGATGCCACACATTCTCTCTCAATTTCAGCTTCGGAACGCTATGAAAATAATACATGATTAAAGTTTCACAGATCTTCTTGG
ACATTGTATAATTGAATTTGAATGTGAGATTTCTCCAGTTATCAAGAGACTAAGGATTTTTTTTTTTTTTTGACAAAAGGAGGATACAGG
AAGAAAATTCAGACTCATTTGAATATTTGTAAACCATGTAATATATAAATAACCACTTTCAATTCTTTTGGCCCTGAGCTATCTCCATTA
CTTAATAGAAAAACTTAGATAAAAAACACTTTAAGACTCTTCTATTCACATTGAAATAAAGAATTATCTAGATGATAATTCAGATAATTC
AGTTTGTTCATAGAATTACTTTCTTATCACTCTTTTTCTACTACTTTTTCTCAAATACCTCTCTAATCCAAGAGGCACTTCCAAGAAATT
CCACACATTCCTTATATCCCTTTTTTGCTTGTCTAGCAAAGCTTGTTTGTATATATGCACCCCATTGTAAAGCAGGTATGCAGGTATGTG
GGTGAAAGTGACTATGAAAAGACTTAATGAATTCTGGGATTTGTAATGGTATTGATGGGTATCTCTGTATGTATATCAAGAGTGGGCAGA
AATGTTTGGCTGGTGATGGCAAATGACTGGCTTTCTCTTGTGGATGGACTATAGGAAGCACTTTCTGAATTATGTAATGATTTGGACCAA
AAAGTATTTTGCTGAAATACTCAGGTAATTGAGATAGCAATGGTTTTATGGCATGAATTATCCAAAAAAATATCAGAATTACTTATTATT
CTGTGATTTCATTAGCTCATTAATGTTTAACTCACAGATTGGGCATCACCATCTAGAATTTCAGTTTAAGGGAGGCCTGCGCAAAGCTAG
TTTTATTTCTTAAAGGATAACAGTCATACATAGAATACTAGGAAAGCCAATATTCTATTTAAAAATAAACTTCTGATGCATTTTCATTCT
TAGCAGAAAGGTAAATGCTTGAGAAAGCTTGAGTCAAATTTGTTAAAAGAATTTTGAGTTCTATAAATCCAAAAATCTGAAACCTGAATT
TATTTAAATTTATAATCCTTTATTTTTTAATACCGTGCCATTTTCCACAAAGGATTTGTGGTTGGTATATAATTCTTTAAAGATACCTGG

>In-frame_ENST00000261908_ENST00000327171_TCGA-BR-A4J5-01A_NEO1_chr15_73470768_+_GALK2_chr15_49620149_length(amino acids)=521AA_start in transcript=12_stop in transcript=1577
MESPLQREGLRGPGRAGLGWSSGGRGSRACSEGPAEARGREGGKGSAALSPPLPLTLGEEMAAERGARRLLSTPSFWLYCLLLLGRRAPG
AAAARSGSAPQSPGASIRTFTPFYFLVEPVDTLSVRGSSVILNCSAYSEPSPKIEWKKDGTFLNLVSDDRRQLLPDGSLFISNVVHSKHN
KPDEGYYQCVATVESLGTIISRTAKLIVAGLPRFTSQPEPSSVYAGNNAILNCEVNADLVPFVRWEQNRQPLLLDDRVIKLPSGMLVISN
ATEGDGGLYRCVVESGGPPKYSDEVELKVLPDPEVISDLVFLKQPSPLVRVIGQDVVLPCVASGLPTPTIKWMKNEEALDTESSERLVLL
AGGSLEISDVTEDDAGTYFCIADNGNETIEAQAELTVQAQPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYFKIV

--------------------------------------------------------------
>In-frame_ENST00000261908_ENST00000560031_TCGA-BR-A4J5-01A_NEO1_chr15_73470768_+_GALK2_chr15_49620149_length(transcript)=2050nt_BP=1483nt
GAGGGAGGCGCCCTGGAGTCTCCCCTCCAGCGAGAGGGGCTGCGCGGGCCGGGCCGGGCCGGGCTGGGCTGGAGCAGCGGCGGCCGCGGG
AGCCGAGCTTGCAGCGAGGGACCGGCTGAGGCGCGCGGGAGGGAAGGAGGCAAGGGCTCCGCGGCGCTGTCGCCGCCGCTGCCGCTCACT
CTCGGGGAAGAGATGGCGGCGGAGCGGGGAGCCCGGCGACTCCTCAGCACCCCCTCCTTCTGGCTCTACTGCCTGCTGCTGCTCGGGCGC
CGGGCGCCGGGCGCCGCGGCCGCCAGGAGCGGCTCCGCGCCGCAGTCCCCAGGAGCCAGCATTCGAACGTTCACTCCATTTTATTTTCTG
GTGGAGCCGGTGGATACACTCTCAGTTAGAGGCTCTTCTGTTATATTAAACTGTTCAGCATATTCTGAGCCTTCTCCAAAAATTGAATGG
AAAAAAGATGGAACTTTTTTAAACTTAGTATCAGATGATCGACGCCAGCTTCTCCCGGATGGATCTTTATTTATCAGCAATGTGGTGCAT
TCCAAACACAATAAACCTGATGAAGGTTATTATCAGTGTGTGGCCACTGTTGAGAGTCTTGGAACTATTATCAGTAGAACAGCGAAGCTC
ATAGTAGCAGGTCTTCCAAGATTTACCAGCCAACCAGAACCTTCCTCAGTTTATGCTGGGAACAATGCAATTCTGAATTGTGAAGTTAAT
GCAGATTTGGTCCCATTTGTGAGGTGGGAACAGAACAGACAACCCCTTCTTCTGGATGATAGAGTTATCAAACTTCCAAGTGGAATGCTG
GTTATCAGCAATGCAACTGAAGGAGATGGCGGGCTTTATCGCTGCGTAGTGGAAAGTGGTGGGCCACCAAAGTATAGTGATGAAGTTGAA
TTGAAGGTTCTTCCAGATCCTGAGGTGATATCAGACTTGGTATTTTTGAAACAGCCTTCTCCCTTAGTCAGAGTCATTGGTCAGGATGTA
GTGTTGCCATGTGTTGCTTCAGGACTTCCTACTCCAACCATTAAATGGATGAAAAATGAGGAGGCACTTGACACAGAAAGCTCTGAAAGA
TTGGTATTGCTGGCAGGTGGTAGCCTGGAGATCAGTGATGTTACTGAGGATGATGCTGGGACTTATTTTTGTATAGCTGATAATGGAAAT
GAGACAATTGAAGCTCAAGCAGAGCTTACAGTGCAAGCTCAACCTGAATTCCTGAAGCAGCCTACTAATATATATGCTCACGAATCTATG
GATATTGTATTTGAATGTGAAGTGACTGGAAAACCAACTCCAACTGTGAAGTGGGTCAAAAATGGGGATATGGTTATCCCAAGTGATTAT
TTTAAGATTGTAAAGGAACATAATCTTCAAGTTTTGGGTCTGGTGAAATCAGATGAAGGGTTCTATCAGTGCATTGCTGAAAATGATGTT
GGAAATGCACAAGCTGGAGCCCAACTGATAATCCTTGAACATGGAAGTTTGGGGCTCAAGGGTCACGACTTACTGGAGCAGGATGGGGAG
GCTGCACAGTATCAATGGTACCTGCGGACAAGCTGCCCAGCTTTCTAGCAAATGTGCACAAAGCTTATTACCAGAGGAGTGATGGAAGCT
TAGCACCGGAGAAGCAAAGTTTGTTTGCTACCAAACCTGGAGGTGGGGCTTTGGTTTTGCTTGAGGCCTGAAAAAATGTAAAAAGTCTGA
GAGAAACTACTTAGGGCACTTAGGAATTGGCAGGACTTTCTGTGCCACAGTAAATTAATCTTCCTTCTGTTTTGTATTATGATGAACGGT
TGCTATTATATCAAGATATATTTTCAAAGAAATGGTTGAAAGCTCTCTATGCTTCATAATGATTCTTTTTCCATCTTAAAATATGGTTTT
ACTATTAAGAGCCAAGATCATGCTTGGACAGATCTTTTAAGAATAACTTACTGAGATTTATTGATTTGAAGATTTTAAAGATGAATGGTA

>In-frame_ENST00000261908_ENST00000560031_TCGA-BR-A4J5-01A_NEO1_chr15_73470768_+_GALK2_chr15_49620149_length(amino acids)=521AA_start in transcript=12_stop in transcript=1577
MESPLQREGLRGPGRAGLGWSSGGRGSRACSEGPAEARGREGGKGSAALSPPLPLTLGEEMAAERGARRLLSTPSFWLYCLLLLGRRAPG
AAAARSGSAPQSPGASIRTFTPFYFLVEPVDTLSVRGSSVILNCSAYSEPSPKIEWKKDGTFLNLVSDDRRQLLPDGSLFISNVVHSKHN
KPDEGYYQCVATVESLGTIISRTAKLIVAGLPRFTSQPEPSSVYAGNNAILNCEVNADLVPFVRWEQNRQPLLLDDRVIKLPSGMLVISN
ATEGDGGLYRCVVESGGPPKYSDEVELKVLPDPEVISDLVFLKQPSPLVRVIGQDVVLPCVASGLPTPTIKWMKNEEALDTESSERLVLL
AGGSLEISDVTEDDAGTYFCIADNGNETIEAQAELTVQAQPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYFKIV

--------------------------------------------------------------
>In-frame_ENST00000558964_ENST00000327171_TCGA-BR-A4J5-01A_NEO1_chr15_73470768_+_GALK2_chr15_49620149_length(transcript)=3211nt_BP=1357nt
GGGAGGGAAGGAGGCAAGGGCTCCGCGGCGCTGTCGCCGCCGCTGCCGCTCACTCTCGGGGAAGAGATGGCGGCGGAGCGGGGAGCCCGG
CGACTCCTCAGCACCCCCTCCTTCTGGCTCTACTGCCTGCTGCTGCTCGGGCGCCGGGCGCCGGGCGCCGCGGCCGCCAGGAGCGGCTCC
GCGCCGCAGTCCCCAGGAGCCAGCATTCGAACGTTCACTCCATTTTATTTTCTGGTGGAGCCGGTGGATACACTCTCAGTTAGAGGCTCT
TCTGTTATATTAAACTGTTCAGCATATTCTGAGCCTTCTCCAAAAATTGAATGGAAAAAAGATGGAACTTTTTTAAACTTAGTATCAGAT
GATCGACGCCAGCTTCTCCCGGATGGATCTTTATTTATCAGCAATGTGGTGCATTCCAAACACAATAAACCTGATGAAGGTTATTATCAG
TGTGTGGCCACTGTTGAGAGTCTTGGAACTATTATCAGTAGAACAGCGAAGCTCATAGTAGCAGGTCTTCCAAGATTTACCAGCCAACCA
GAACCTTCCTCAGTTTATGCTGGGAACAATGCAATTCTGAATTGTGAAGTTAATGCAGATTTGGTCCCATTTGTGAGGTGGGAACAGAAC
AGACAACCCCTTCTTCTGGATGATAGAGTTATCAAACTTCCAAGTGGAATGCTGGTTATCAGCAATGCAACTGAAGGAGATGGCGGGCTT
TATCGCTGCGTAGTGGAAAGTGGTGGGCCACCAAAGTATAGTGATGAAGTTGAATTGAAGGTTCTTCCAGATCCTGAGGTGATATCAGAC
TTGGTATTTTTGAAACAGCCTTCTCCCTTAGTCAGAGTCATTGGTCAGGATGTAGTGTTGCCATGTGTTGCTTCAGGACTTCCTACTCCA
ACCATTAAATGGATGAAAAATGAGGAGGCACTTGACACAGAAAGCTCTGAAAGATTGGTATTGCTGGCAGGTGGTAGCCTGGAGATCAGT
GATGTTACTGAGGATGATGCTGGGACTTATTTTTGTATAGCTGATAATGGAAATGAGACAATTGAAGCTCAAGCAGAGCTTACAGTGCAA
GCTCAACCTGAATTCCTGAAGCAGCCTACTAATATATATGCTCACGAATCTATGGATATTGTATTTGAATGTGAAGTGACTGGAAAACCA
ACTCCAACTGTGAAGTGGGTCAAAAATGGGGATATGGTTATCCCAAGTGATTATTTTAAGATTGTAAAGGAACATAATCTTCAAGTTTTG
GGTCTGGTGAAATCAGATGAAGGGTTCTATCAGTGCATTGCTGAAAATGATGTTGGAAATGCACAAGCTGGAGCCCAACTGATAATCCTT
GAACATGGAAGTTTGGGGCTCAAGGGTCACGACTTACTGGAGCAGGATGGGGAGGCTGCACAGTATCAATGGTACCTGCGGACAAGCTGC
CCAGCTTTCTAGCAAATGTGCACAAAGCTTATTACCAGAGGAGTGATGGAAGCTTAGCACCGGAGAAGCAAAGTTTGTTTGCTACCAAAC
CTGGAGGTGGGGCTTTGGTTTTGCTTGAGGCCTGAAAAAATGTAAAAAGTCTGAGAGAAACTACTTAGGGCACTTAGGAATTGGCAGGAC
TTTCTGTGCCACAGTAAATTAATCTTCCTTCTGTTTTGTATTATGATGAACGGTTGCTATTATATCAAGATATATTTTCAAAGAAATGGT
TGAAAGCTCTCTATGCTTCATAATGATTCTTTTTCCATCTTAAAATATGGTTTTACTATTAAGAGCCAAGATCATGCTTGGACAGATCTT
TTAAGAATAACTTACTGAGATTTATTGATTTGAAGATTTTAAAGATGAATGGTAAAACACACTCTTAATACTGATTACATGGATTGGACT
TGAATTAAATATATTGTTACAATTAAACTGATACCACTGAATTGTATGCATTATTCTTGAATAGAGTTCATTTCTGGTTTCTCTTAGTAT
TCTTCTTCCTCAAAGTTGTAGTTGTCTGTTGATGATGGTGATGATGATGATGATGACGATAGTGATGCCACACATTCTCTCTCAATTTCA
GCTTCGGAACGCTATGAAAATAATACATGATTAAAGTTTCACAGATCTTCTTGGACATTGTATAATTGAATTTGAATGTGAGATTTCTCC
AGTTATCAAGAGACTAAGGATTTTTTTTTTTTTTTGACAAAAGGAGGATACAGGAAGAAAATTCAGACTCATTTGAATATTTGTAAACCA
TGTAATATATAAATAACCACTTTCAATTCTTTTGGCCCTGAGCTATCTCCATTACTTAATAGAAAAACTTAGATAAAAAACACTTTAAGA
CTCTTCTATTCACATTGAAATAAAGAATTATCTAGATGATAATTCAGATAATTCAGTTTGTTCATAGAATTACTTTCTTATCACTCTTTT
TCTACTACTTTTTCTCAAATACCTCTCTAATCCAAGAGGCACTTCCAAGAAATTCCACACATTCCTTATATCCCTTTTTTGCTTGTCTAG
CAAAGCTTGTTTGTATATATGCACCCCATTGTAAAGCAGGTATGCAGGTATGTGGGTGAAAGTGACTATGAAAAGACTTAATGAATTCTG
GGATTTGTAATGGTATTGATGGGTATCTCTGTATGTATATCAAGAGTGGGCAGAAATGTTTGGCTGGTGATGGCAAATGACTGGCTTTCT
CTTGTGGATGGACTATAGGAAGCACTTTCTGAATTATGTAATGATTTGGACCAAAAAGTATTTTGCTGAAATACTCAGGTAATTGAGATA
GCAATGGTTTTATGGCATGAATTATCCAAAAAAATATCAGAATTACTTATTATTCTGTGATTTCATTAGCTCATTAATGTTTAACTCACA
GATTGGGCATCACCATCTAGAATTTCAGTTTAAGGGAGGCCTGCGCAAAGCTAGTTTTATTTCTTAAAGGATAACAGTCATACATAGAAT
ACTAGGAAAGCCAATATTCTATTTAAAAATAAACTTCTGATGCATTTTCATTCTTAGCAGAAAGGTAAATGCTTGAGAAAGCTTGAGTCA
AATTTGTTAAAAGAATTTTGAGTTCTATAAATCCAAAAATCTGAAACCTGAATTTATTTAAATTTATAATCCTTTATTTTTTAATACCGT

>In-frame_ENST00000558964_ENST00000327171_TCGA-BR-A4J5-01A_NEO1_chr15_73470768_+_GALK2_chr15_49620149_length(amino acids)=473AA_start in transcript=30_stop in transcript=1451
MSPPLPLTLGEEMAAERGARRLLSTPSFWLYCLLLLGRRAPGAAAARSGSAPQSPGASIRTFTPFYFLVEPVDTLSVRGSSVILNCSAYS
EPSPKIEWKKDGTFLNLVSDDRRQLLPDGSLFISNVVHSKHNKPDEGYYQCVATVESLGTIISRTAKLIVAGLPRFTSQPEPSSVYAGNN
AILNCEVNADLVPFVRWEQNRQPLLLDDRVIKLPSGMLVISNATEGDGGLYRCVVESGGPPKYSDEVELKVLPDPEVISDLVFLKQPSPL
VRVIGQDVVLPCVASGLPTPTIKWMKNEEALDTESSERLVLLAGGSLEISDVTEDDAGTYFCIADNGNETIEAQAELTVQAQPEFLKQPT
NIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYFKIVKEHNLQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHGSLGLKGH

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>In-frame_ENST00000558964_ENST00000560031_TCGA-BR-A4J5-01A_NEO1_chr15_73470768_+_GALK2_chr15_49620149_length(transcript)=1924nt_BP=1357nt
GGGAGGGAAGGAGGCAAGGGCTCCGCGGCGCTGTCGCCGCCGCTGCCGCTCACTCTCGGGGAAGAGATGGCGGCGGAGCGGGGAGCCCGG
CGACTCCTCAGCACCCCCTCCTTCTGGCTCTACTGCCTGCTGCTGCTCGGGCGCCGGGCGCCGGGCGCCGCGGCCGCCAGGAGCGGCTCC
GCGCCGCAGTCCCCAGGAGCCAGCATTCGAACGTTCACTCCATTTTATTTTCTGGTGGAGCCGGTGGATACACTCTCAGTTAGAGGCTCT
TCTGTTATATTAAACTGTTCAGCATATTCTGAGCCTTCTCCAAAAATTGAATGGAAAAAAGATGGAACTTTTTTAAACTTAGTATCAGAT
GATCGACGCCAGCTTCTCCCGGATGGATCTTTATTTATCAGCAATGTGGTGCATTCCAAACACAATAAACCTGATGAAGGTTATTATCAG
TGTGTGGCCACTGTTGAGAGTCTTGGAACTATTATCAGTAGAACAGCGAAGCTCATAGTAGCAGGTCTTCCAAGATTTACCAGCCAACCA
GAACCTTCCTCAGTTTATGCTGGGAACAATGCAATTCTGAATTGTGAAGTTAATGCAGATTTGGTCCCATTTGTGAGGTGGGAACAGAAC
AGACAACCCCTTCTTCTGGATGATAGAGTTATCAAACTTCCAAGTGGAATGCTGGTTATCAGCAATGCAACTGAAGGAGATGGCGGGCTT
TATCGCTGCGTAGTGGAAAGTGGTGGGCCACCAAAGTATAGTGATGAAGTTGAATTGAAGGTTCTTCCAGATCCTGAGGTGATATCAGAC
TTGGTATTTTTGAAACAGCCTTCTCCCTTAGTCAGAGTCATTGGTCAGGATGTAGTGTTGCCATGTGTTGCTTCAGGACTTCCTACTCCA
ACCATTAAATGGATGAAAAATGAGGAGGCACTTGACACAGAAAGCTCTGAAAGATTGGTATTGCTGGCAGGTGGTAGCCTGGAGATCAGT
GATGTTACTGAGGATGATGCTGGGACTTATTTTTGTATAGCTGATAATGGAAATGAGACAATTGAAGCTCAAGCAGAGCTTACAGTGCAA
GCTCAACCTGAATTCCTGAAGCAGCCTACTAATATATATGCTCACGAATCTATGGATATTGTATTTGAATGTGAAGTGACTGGAAAACCA
ACTCCAACTGTGAAGTGGGTCAAAAATGGGGATATGGTTATCCCAAGTGATTATTTTAAGATTGTAAAGGAACATAATCTTCAAGTTTTG
GGTCTGGTGAAATCAGATGAAGGGTTCTATCAGTGCATTGCTGAAAATGATGTTGGAAATGCACAAGCTGGAGCCCAACTGATAATCCTT
GAACATGGAAGTTTGGGGCTCAAGGGTCACGACTTACTGGAGCAGGATGGGGAGGCTGCACAGTATCAATGGTACCTGCGGACAAGCTGC
CCAGCTTTCTAGCAAATGTGCACAAAGCTTATTACCAGAGGAGTGATGGAAGCTTAGCACCGGAGAAGCAAAGTTTGTTTGCTACCAAAC
CTGGAGGTGGGGCTTTGGTTTTGCTTGAGGCCTGAAAAAATGTAAAAAGTCTGAGAGAAACTACTTAGGGCACTTAGGAATTGGCAGGAC
TTTCTGTGCCACAGTAAATTAATCTTCCTTCTGTTTTGTATTATGATGAACGGTTGCTATTATATCAAGATATATTTTCAAAGAAATGGT
TGAAAGCTCTCTATGCTTCATAATGATTCTTTTTCCATCTTAAAATATGGTTTTACTATTAAGAGCCAAGATCATGCTTGGACAGATCTT
TTAAGAATAACTTACTGAGATTTATTGATTTGAAGATTTTAAAGATGAATGGTAAAACACACTCTTAATACTGATTACATGGATTGGACT

>In-frame_ENST00000558964_ENST00000560031_TCGA-BR-A4J5-01A_NEO1_chr15_73470768_+_GALK2_chr15_49620149_length(amino acids)=473AA_start in transcript=30_stop in transcript=1451
MSPPLPLTLGEEMAAERGARRLLSTPSFWLYCLLLLGRRAPGAAAARSGSAPQSPGASIRTFTPFYFLVEPVDTLSVRGSSVILNCSAYS
EPSPKIEWKKDGTFLNLVSDDRRQLLPDGSLFISNVVHSKHNKPDEGYYQCVATVESLGTIISRTAKLIVAGLPRFTSQPEPSSVYAGNN
AILNCEVNADLVPFVRWEQNRQPLLLDDRVIKLPSGMLVISNATEGDGGLYRCVVESGGPPKYSDEVELKVLPDPEVISDLVFLKQPSPL
VRVIGQDVVLPCVASGLPTPTIKWMKNEEALDTESSERLVLLAGGSLEISDVTEDDAGTYFCIADNGNETIEAQAELTVQAQPEFLKQPT
NIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYFKIVKEHNLQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHGSLGLKGH

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>In-frame_ENST00000560262_ENST00000327171_TCGA-BR-A4J5-01A_NEO1_chr15_73470768_+_GALK2_chr15_49620149_length(transcript)=3211nt_BP=1357nt
GGGAGGGAAGGAGGCAAGGGCTCCGCGGCGCTGTCGCCGCCGCTGCCGCTCACTCTCGGGGAAGAGATGGCGGCGGAGCGGGGAGCCCGG
CGACTCCTCAGCACCCCCTCCTTCTGGCTCTACTGCCTGCTGCTGCTCGGGCGCCGGGCGCCGGGCGCCGCGGCCGCCAGGAGCGGCTCC
GCGCCGCAGTCCCCAGGAGCCAGCATTCGAACGTTCACTCCATTTTATTTTCTGGTGGAGCCGGTGGATACACTCTCAGTTAGAGGCTCT
TCTGTTATATTAAACTGTTCAGCATATTCTGAGCCTTCTCCAAAAATTGAATGGAAAAAAGATGGAACTTTTTTAAACTTAGTATCAGAT
GATCGACGCCAGCTTCTCCCGGATGGATCTTTATTTATCAGCAATGTGGTGCATTCCAAACACAATAAACCTGATGAAGGTTATTATCAG
TGTGTGGCCACTGTTGAGAGTCTTGGAACTATTATCAGTAGAACAGCGAAGCTCATAGTAGCAGGTCTTCCAAGATTTACCAGCCAACCA
GAACCTTCCTCAGTTTATGCTGGGAACAATGCAATTCTGAATTGTGAAGTTAATGCAGATTTGGTCCCATTTGTGAGGTGGGAACAGAAC
AGACAACCCCTTCTTCTGGATGATAGAGTTATCAAACTTCCAAGTGGAATGCTGGTTATCAGCAATGCAACTGAAGGAGATGGCGGGCTT
TATCGCTGCGTAGTGGAAAGTGGTGGGCCACCAAAGTATAGTGATGAAGTTGAATTGAAGGTTCTTCCAGATCCTGAGGTGATATCAGAC
TTGGTATTTTTGAAACAGCCTTCTCCCTTAGTCAGAGTCATTGGTCAGGATGTAGTGTTGCCATGTGTTGCTTCAGGACTTCCTACTCCA
ACCATTAAATGGATGAAAAATGAGGAGGCACTTGACACAGAAAGCTCTGAAAGATTGGTATTGCTGGCAGGTGGTAGCCTGGAGATCAGT
GATGTTACTGAGGATGATGCTGGGACTTATTTTTGTATAGCTGATAATGGAAATGAGACAATTGAAGCTCAAGCAGAGCTTACAGTGCAA
GCTCAACCTGAATTCCTGAAGCAGCCTACTAATATATATGCTCACGAATCTATGGATATTGTATTTGAATGTGAAGTGACTGGAAAACCA
ACTCCAACTGTGAAGTGGGTCAAAAATGGGGATATGGTTATCCCAAGTGATTATTTTAAGATTGTAAAGGAACATAATCTTCAAGTTTTG
GGTCTGGTGAAATCAGATGAAGGGTTCTATCAGTGCATTGCTGAAAATGATGTTGGAAATGCACAAGCTGGAGCCCAACTGATAATCCTT
GAACATGGAAGTTTGGGGCTCAAGGGTCACGACTTACTGGAGCAGGATGGGGAGGCTGCACAGTATCAATGGTACCTGCGGACAAGCTGC
CCAGCTTTCTAGCAAATGTGCACAAAGCTTATTACCAGAGGAGTGATGGAAGCTTAGCACCGGAGAAGCAAAGTTTGTTTGCTACCAAAC
CTGGAGGTGGGGCTTTGGTTTTGCTTGAGGCCTGAAAAAATGTAAAAAGTCTGAGAGAAACTACTTAGGGCACTTAGGAATTGGCAGGAC
TTTCTGTGCCACAGTAAATTAATCTTCCTTCTGTTTTGTATTATGATGAACGGTTGCTATTATATCAAGATATATTTTCAAAGAAATGGT
TGAAAGCTCTCTATGCTTCATAATGATTCTTTTTCCATCTTAAAATATGGTTTTACTATTAAGAGCCAAGATCATGCTTGGACAGATCTT
TTAAGAATAACTTACTGAGATTTATTGATTTGAAGATTTTAAAGATGAATGGTAAAACACACTCTTAATACTGATTACATGGATTGGACT
TGAATTAAATATATTGTTACAATTAAACTGATACCACTGAATTGTATGCATTATTCTTGAATAGAGTTCATTTCTGGTTTCTCTTAGTAT
TCTTCTTCCTCAAAGTTGTAGTTGTCTGTTGATGATGGTGATGATGATGATGATGACGATAGTGATGCCACACATTCTCTCTCAATTTCA
GCTTCGGAACGCTATGAAAATAATACATGATTAAAGTTTCACAGATCTTCTTGGACATTGTATAATTGAATTTGAATGTGAGATTTCTCC
AGTTATCAAGAGACTAAGGATTTTTTTTTTTTTTTGACAAAAGGAGGATACAGGAAGAAAATTCAGACTCATTTGAATATTTGTAAACCA
TGTAATATATAAATAACCACTTTCAATTCTTTTGGCCCTGAGCTATCTCCATTACTTAATAGAAAAACTTAGATAAAAAACACTTTAAGA
CTCTTCTATTCACATTGAAATAAAGAATTATCTAGATGATAATTCAGATAATTCAGTTTGTTCATAGAATTACTTTCTTATCACTCTTTT
TCTACTACTTTTTCTCAAATACCTCTCTAATCCAAGAGGCACTTCCAAGAAATTCCACACATTCCTTATATCCCTTTTTTGCTTGTCTAG
CAAAGCTTGTTTGTATATATGCACCCCATTGTAAAGCAGGTATGCAGGTATGTGGGTGAAAGTGACTATGAAAAGACTTAATGAATTCTG
GGATTTGTAATGGTATTGATGGGTATCTCTGTATGTATATCAAGAGTGGGCAGAAATGTTTGGCTGGTGATGGCAAATGACTGGCTTTCT
CTTGTGGATGGACTATAGGAAGCACTTTCTGAATTATGTAATGATTTGGACCAAAAAGTATTTTGCTGAAATACTCAGGTAATTGAGATA
GCAATGGTTTTATGGCATGAATTATCCAAAAAAATATCAGAATTACTTATTATTCTGTGATTTCATTAGCTCATTAATGTTTAACTCACA
GATTGGGCATCACCATCTAGAATTTCAGTTTAAGGGAGGCCTGCGCAAAGCTAGTTTTATTTCTTAAAGGATAACAGTCATACATAGAAT
ACTAGGAAAGCCAATATTCTATTTAAAAATAAACTTCTGATGCATTTTCATTCTTAGCAGAAAGGTAAATGCTTGAGAAAGCTTGAGTCA
AATTTGTTAAAAGAATTTTGAGTTCTATAAATCCAAAAATCTGAAACCTGAATTTATTTAAATTTATAATCCTTTATTTTTTAATACCGT

>In-frame_ENST00000560262_ENST00000327171_TCGA-BR-A4J5-01A_NEO1_chr15_73470768_+_GALK2_chr15_49620149_length(amino acids)=473AA_start in transcript=30_stop in transcript=1451
MSPPLPLTLGEEMAAERGARRLLSTPSFWLYCLLLLGRRAPGAAAARSGSAPQSPGASIRTFTPFYFLVEPVDTLSVRGSSVILNCSAYS
EPSPKIEWKKDGTFLNLVSDDRRQLLPDGSLFISNVVHSKHNKPDEGYYQCVATVESLGTIISRTAKLIVAGLPRFTSQPEPSSVYAGNN
AILNCEVNADLVPFVRWEQNRQPLLLDDRVIKLPSGMLVISNATEGDGGLYRCVVESGGPPKYSDEVELKVLPDPEVISDLVFLKQPSPL
VRVIGQDVVLPCVASGLPTPTIKWMKNEEALDTESSERLVLLAGGSLEISDVTEDDAGTYFCIADNGNETIEAQAELTVQAQPEFLKQPT
NIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYFKIVKEHNLQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHGSLGLKGH

--------------------------------------------------------------
>In-frame_ENST00000560262_ENST00000560031_TCGA-BR-A4J5-01A_NEO1_chr15_73470768_+_GALK2_chr15_49620149_length(transcript)=1924nt_BP=1357nt
GGGAGGGAAGGAGGCAAGGGCTCCGCGGCGCTGTCGCCGCCGCTGCCGCTCACTCTCGGGGAAGAGATGGCGGCGGAGCGGGGAGCCCGG
CGACTCCTCAGCACCCCCTCCTTCTGGCTCTACTGCCTGCTGCTGCTCGGGCGCCGGGCGCCGGGCGCCGCGGCCGCCAGGAGCGGCTCC
GCGCCGCAGTCCCCAGGAGCCAGCATTCGAACGTTCACTCCATTTTATTTTCTGGTGGAGCCGGTGGATACACTCTCAGTTAGAGGCTCT
TCTGTTATATTAAACTGTTCAGCATATTCTGAGCCTTCTCCAAAAATTGAATGGAAAAAAGATGGAACTTTTTTAAACTTAGTATCAGAT
GATCGACGCCAGCTTCTCCCGGATGGATCTTTATTTATCAGCAATGTGGTGCATTCCAAACACAATAAACCTGATGAAGGTTATTATCAG
TGTGTGGCCACTGTTGAGAGTCTTGGAACTATTATCAGTAGAACAGCGAAGCTCATAGTAGCAGGTCTTCCAAGATTTACCAGCCAACCA
GAACCTTCCTCAGTTTATGCTGGGAACAATGCAATTCTGAATTGTGAAGTTAATGCAGATTTGGTCCCATTTGTGAGGTGGGAACAGAAC
AGACAACCCCTTCTTCTGGATGATAGAGTTATCAAACTTCCAAGTGGAATGCTGGTTATCAGCAATGCAACTGAAGGAGATGGCGGGCTT
TATCGCTGCGTAGTGGAAAGTGGTGGGCCACCAAAGTATAGTGATGAAGTTGAATTGAAGGTTCTTCCAGATCCTGAGGTGATATCAGAC
TTGGTATTTTTGAAACAGCCTTCTCCCTTAGTCAGAGTCATTGGTCAGGATGTAGTGTTGCCATGTGTTGCTTCAGGACTTCCTACTCCA
ACCATTAAATGGATGAAAAATGAGGAGGCACTTGACACAGAAAGCTCTGAAAGATTGGTATTGCTGGCAGGTGGTAGCCTGGAGATCAGT
GATGTTACTGAGGATGATGCTGGGACTTATTTTTGTATAGCTGATAATGGAAATGAGACAATTGAAGCTCAAGCAGAGCTTACAGTGCAA
GCTCAACCTGAATTCCTGAAGCAGCCTACTAATATATATGCTCACGAATCTATGGATATTGTATTTGAATGTGAAGTGACTGGAAAACCA
ACTCCAACTGTGAAGTGGGTCAAAAATGGGGATATGGTTATCCCAAGTGATTATTTTAAGATTGTAAAGGAACATAATCTTCAAGTTTTG
GGTCTGGTGAAATCAGATGAAGGGTTCTATCAGTGCATTGCTGAAAATGATGTTGGAAATGCACAAGCTGGAGCCCAACTGATAATCCTT
GAACATGGAAGTTTGGGGCTCAAGGGTCACGACTTACTGGAGCAGGATGGGGAGGCTGCACAGTATCAATGGTACCTGCGGACAAGCTGC
CCAGCTTTCTAGCAAATGTGCACAAAGCTTATTACCAGAGGAGTGATGGAAGCTTAGCACCGGAGAAGCAAAGTTTGTTTGCTACCAAAC
CTGGAGGTGGGGCTTTGGTTTTGCTTGAGGCCTGAAAAAATGTAAAAAGTCTGAGAGAAACTACTTAGGGCACTTAGGAATTGGCAGGAC
TTTCTGTGCCACAGTAAATTAATCTTCCTTCTGTTTTGTATTATGATGAACGGTTGCTATTATATCAAGATATATTTTCAAAGAAATGGT
TGAAAGCTCTCTATGCTTCATAATGATTCTTTTTCCATCTTAAAATATGGTTTTACTATTAAGAGCCAAGATCATGCTTGGACAGATCTT
TTAAGAATAACTTACTGAGATTTATTGATTTGAAGATTTTAAAGATGAATGGTAAAACACACTCTTAATACTGATTACATGGATTGGACT

>In-frame_ENST00000560262_ENST00000560031_TCGA-BR-A4J5-01A_NEO1_chr15_73470768_+_GALK2_chr15_49620149_length(amino acids)=473AA_start in transcript=30_stop in transcript=1451
MSPPLPLTLGEEMAAERGARRLLSTPSFWLYCLLLLGRRAPGAAAARSGSAPQSPGASIRTFTPFYFLVEPVDTLSVRGSSVILNCSAYS
EPSPKIEWKKDGTFLNLVSDDRRQLLPDGSLFISNVVHSKHNKPDEGYYQCVATVESLGTIISRTAKLIVAGLPRFTSQPEPSSVYAGNN
AILNCEVNADLVPFVRWEQNRQPLLLDDRVIKLPSGMLVISNATEGDGGLYRCVVESGGPPKYSDEVELKVLPDPEVISDLVFLKQPSPL
VRVIGQDVVLPCVASGLPTPTIKWMKNEEALDTESSERLVLLAGGSLEISDVTEDDAGTYFCIADNGNETIEAQAELTVQAQPEFLKQPT
NIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYFKIVKEHNLQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHGSLGLKGH

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Fusion Gene PPI Analysis for NEO1-GALK2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for NEO1-GALK2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for NEO1-GALK2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource