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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:NF1-ABCB5 (FusionGDB2 ID:58316)

Fusion Gene Summary for NF1-ABCB5

check button Fusion gene summary
Fusion gene informationFusion gene name: NF1-ABCB5
Fusion gene ID: 58316
HgeneTgene
Gene symbol

NF1

ABCB5

Gene ID

4763

340273

Gene nameneurofibromin 1ATP binding cassette subfamily B member 5
SynonymsNFNS|VRNF|WSSABCB5alpha|ABCB5beta|EST422562
Cytomap

17q11.2

7p21.1

Type of geneprotein-codingprotein-coding
Descriptionneurofibrominneurofibromatosis 1neurofibromatosis-related protein NF-1truncated neurofibromin 1ATP-binding cassette sub-family B member 5ABCB5 P-gpATP-binding cassette proteinATP-binding cassette, sub-family B (MDR/TAP), member 5P-glycoprotein ABCB5
Modification date2020032220200313
UniProtAcc.

Q2M3G0

Ensembl transtripts involved in fusion geneENST00000356175, ENST00000358273, 
ENST00000431387, ENST00000581113, 
ENST00000417592, ENST00000444181, 
ENST00000404938, ENST00000258738, 
ENST00000477094, ENST00000443026, 
ENST00000406935, 
Fusion gene scores* DoF score47 X 26 X 21=256628 X 7 X 5=280
# samples 698
** MAII scorelog2(69/25662*10)=-5.21689344093196
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(8/280*10)=-1.8073549220576
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: NF1 [Title/Abstract] AND ABCB5 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointNF1(29676269)-ABCB5(20671682), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneNF1

GO:0043547

positive regulation of GTPase activity

2121371

TgeneABCB5

GO:0042391

regulation of membrane potential

12960149

TgeneABCB5

GO:0055085

transmembrane transport

12960149


check buttonFusion gene breakpoints across NF1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across ABCB5 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-B6-A0I9-01ANF1chr17

29676269

-ABCB5chr7

20671682

+


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Fusion Gene ORF analysis for NF1-ABCB5

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000356175ENST00000404938NF1chr17

29676269

-ABCB5chr7

20671682

+
5CDS-intronENST00000356175ENST00000258738NF1chr17

29676269

-ABCB5chr7

20671682

+
5CDS-intronENST00000356175ENST00000477094NF1chr17

29676269

-ABCB5chr7

20671682

+
5CDS-intronENST00000356175ENST00000443026NF1chr17

29676269

-ABCB5chr7

20671682

+
5CDS-intronENST00000356175ENST00000406935NF1chr17

29676269

-ABCB5chr7

20671682

+
In-frameENST00000358273ENST00000404938NF1chr17

29676269

-ABCB5chr7

20671682

+
5CDS-intronENST00000358273ENST00000258738NF1chr17

29676269

-ABCB5chr7

20671682

+
5CDS-intronENST00000358273ENST00000477094NF1chr17

29676269

-ABCB5chr7

20671682

+
5CDS-intronENST00000358273ENST00000443026NF1chr17

29676269

-ABCB5chr7

20671682

+
5CDS-intronENST00000358273ENST00000406935NF1chr17

29676269

-ABCB5chr7

20671682

+
intron-3CDSENST00000431387ENST00000404938NF1chr17

29676269

-ABCB5chr7

20671682

+
intron-intronENST00000431387ENST00000258738NF1chr17

29676269

-ABCB5chr7

20671682

+
intron-intronENST00000431387ENST00000477094NF1chr17

29676269

-ABCB5chr7

20671682

+
intron-intronENST00000431387ENST00000443026NF1chr17

29676269

-ABCB5chr7

20671682

+
intron-intronENST00000431387ENST00000406935NF1chr17

29676269

-ABCB5chr7

20671682

+
intron-3CDSENST00000581113ENST00000404938NF1chr17

29676269

-ABCB5chr7

20671682

+
intron-intronENST00000581113ENST00000258738NF1chr17

29676269

-ABCB5chr7

20671682

+
intron-intronENST00000581113ENST00000477094NF1chr17

29676269

-ABCB5chr7

20671682

+
intron-intronENST00000581113ENST00000443026NF1chr17

29676269

-ABCB5chr7

20671682

+
intron-intronENST00000581113ENST00000406935NF1chr17

29676269

-ABCB5chr7

20671682

+
In-frameENST00000417592ENST00000404938NF1chr17

29676269

-ABCB5chr7

20671682

+
5CDS-intronENST00000417592ENST00000258738NF1chr17

29676269

-ABCB5chr7

20671682

+
5CDS-intronENST00000417592ENST00000477094NF1chr17

29676269

-ABCB5chr7

20671682

+
5CDS-intronENST00000417592ENST00000443026NF1chr17

29676269

-ABCB5chr7

20671682

+
5CDS-intronENST00000417592ENST00000406935NF1chr17

29676269

-ABCB5chr7

20671682

+
In-frameENST00000444181ENST00000404938NF1chr17

29676269

-ABCB5chr7

20671682

+
5CDS-intronENST00000444181ENST00000258738NF1chr17

29676269

-ABCB5chr7

20671682

+
5CDS-intronENST00000444181ENST00000477094NF1chr17

29676269

-ABCB5chr7

20671682

+
5CDS-intronENST00000444181ENST00000443026NF1chr17

29676269

-ABCB5chr7

20671682

+
5CDS-intronENST00000444181ENST00000406935NF1chr17

29676269

-ABCB5chr7

20671682

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000356175NF1chr1729676269-ENST00000404938ABCB5chr720671682+125417641254111553633
ENST00000358273NF1chr1729676269-ENST00000404938ABCB5chr720671682+126047704254112183654
ENST00000417592NF1chr1729676269-ENST00000404938ABCB5chr720671682+5364464439781324
ENST00000444181NF1chr1729676269-ENST00000404938ABCB5chr720671682+5604704442181404

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000356175ENST00000404938NF1chr1729676269-ABCB5chr720671682+0.0003882550.9996118
ENST00000358273ENST00000404938NF1chr1729676269-ABCB5chr720671682+0.0003860590.99961394
ENST00000417592ENST00000404938NF1chr1729676269-ABCB5chr720671682+0.0002148980.9997851
ENST00000444181ENST00000404938NF1chr1729676269-ABCB5chr720671682+0.0002066790.99979335

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Fusion Genomic Features for NF1-ABCB5


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for NF1-ABCB5


check button Go to

FGviewer for the breakpoints of chr17:29676269-chr7:20671682

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.ABCB5

Q2M3G0

FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Energy-dependent efflux transporter responsible for decreased drug accumulation in multidrug-resistant cells (PubMed:12960149, PubMed:22306008, PubMed:15899824, PubMed:15205344). Specifically present in limbal stem cells, where it plays a key role in corneal development and repair (By similarity). {ECO:0000250|UniProtKB:B5X0E4, ECO:0000269|PubMed:12960149, ECO:0000269|PubMed:15205344, ECO:0000269|PubMed:15899824, ECO:0000269|PubMed:22306008}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNF1chr17:29676269chr7:20671682ENST00000356175-48571352_13552419.33333333333352819.0Compositional biasNote=Poly-Ser
HgeneNF1chr17:29676269chr7:20671682ENST00000358273-49581352_13552440.33333333333352840.0Compositional biasNote=Poly-Ser
HgeneNF1chr17:29676269chr7:20671682ENST00000356175-48571235_14512419.33333333333352819.0DomainRas-GAP
HgeneNF1chr17:29676269chr7:20671682ENST00000356175-48571580_17382419.33333333333352819.0DomainCRAL-TRIO
HgeneNF1chr17:29676269chr7:20671682ENST00000358273-49581235_14512440.33333333333352840.0DomainRas-GAP
HgeneNF1chr17:29676269chr7:20671682ENST00000358273-49581580_17382440.33333333333352840.0DomainCRAL-TRIO
HgeneNF1chr17:29676269chr7:20671682ENST00000356175-48571580_18372419.33333333333352819.0RegionNote=Lipid binding
HgeneNF1chr17:29676269chr7:20671682ENST00000358273-49581580_18372440.33333333333352840.0RegionNote=Lipid binding
TgeneABCB5chr17:29676269chr7:20671682ENST000002587380191015_12530813.0DomainABC transporter 2
TgeneABCB5chr17:29676269chr7:20671682ENST00000258738019386_6220813.0DomainABC transporter 1
TgeneABCB5chr17:29676269chr7:20671682ENST0000025873801949_3500813.0DomainABC transmembrane type-1 1
TgeneABCB5chr17:29676269chr7:20671682ENST00000258738019693_9800813.0DomainABC transmembrane type-1 2
TgeneABCB5chr17:29676269chr7:20671682ENST000004049383281015_125386.333333333333331258.0DomainABC transporter 2
TgeneABCB5chr17:29676269chr7:20671682ENST00000404938328386_62286.333333333333331258.0DomainABC transporter 1
TgeneABCB5chr17:29676269chr7:20671682ENST00000404938328693_98086.333333333333331258.0DomainABC transmembrane type-1 2
TgeneABCB5chr17:29676269chr7:20671682ENST00000406935061015_12530127.0DomainABC transporter 2
TgeneABCB5chr17:29676269chr7:20671682ENST0000040693506386_6220127.0DomainABC transporter 1
TgeneABCB5chr17:29676269chr7:20671682ENST000004069350649_3500127.0DomainABC transmembrane type-1 1
TgeneABCB5chr17:29676269chr7:20671682ENST0000040693506693_9800127.0DomainABC transmembrane type-1 2
TgeneABCB5chr17:29676269chr7:20671682ENST00000443026061015_12530132.0DomainABC transporter 2
TgeneABCB5chr17:29676269chr7:20671682ENST0000044302606386_6220132.0DomainABC transporter 1
TgeneABCB5chr17:29676269chr7:20671682ENST000004430260649_3500132.0DomainABC transmembrane type-1 1
TgeneABCB5chr17:29676269chr7:20671682ENST0000044302606693_9800132.0DomainABC transmembrane type-1 2
TgeneABCB5chr17:29676269chr7:20671682ENST000002587380191050_10570813.0Nucleotide bindingATP
TgeneABCB5chr17:29676269chr7:20671682ENST00000258738019421_4280813.0Nucleotide bindingATP
TgeneABCB5chr17:29676269chr7:20671682ENST000004049383281050_105786.333333333333331258.0Nucleotide bindingATP
TgeneABCB5chr17:29676269chr7:20671682ENST00000404938328421_42886.333333333333331258.0Nucleotide bindingATP
TgeneABCB5chr17:29676269chr7:20671682ENST00000406935061050_10570127.0Nucleotide bindingATP
TgeneABCB5chr17:29676269chr7:20671682ENST0000040693506421_4280127.0Nucleotide bindingATP
TgeneABCB5chr17:29676269chr7:20671682ENST00000443026061050_10570132.0Nucleotide bindingATP
TgeneABCB5chr17:29676269chr7:20671682ENST0000044302606421_4280132.0Nucleotide bindingATP
TgeneABCB5chr17:29676269chr7:20671682ENST00000258738019110_1300813.0TransmembraneHelical
TgeneABCB5chr17:29676269chr7:20671682ENST00000258738019181_2010813.0TransmembraneHelical
TgeneABCB5chr17:29676269chr7:20671682ENST00000258738019203_2230813.0TransmembraneHelical
TgeneABCB5chr17:29676269chr7:20671682ENST00000258738019294_3140813.0TransmembraneHelical
TgeneABCB5chr17:29676269chr7:20671682ENST00000258738019322_3420813.0TransmembraneHelical
TgeneABCB5chr17:29676269chr7:20671682ENST0000025873801949_690813.0TransmembraneHelical
TgeneABCB5chr17:29676269chr7:20671682ENST00000258738019693_7130813.0TransmembraneHelical
TgeneABCB5chr17:29676269chr7:20671682ENST00000258738019737_7570813.0TransmembraneHelical
TgeneABCB5chr17:29676269chr7:20671682ENST00000258738019827_8470813.0TransmembraneHelical
TgeneABCB5chr17:29676269chr7:20671682ENST00000258738019917_9370813.0TransmembraneHelical
TgeneABCB5chr17:29676269chr7:20671682ENST00000258738019954_9740813.0TransmembraneHelical
TgeneABCB5chr17:29676269chr7:20671682ENST00000404938328110_13086.333333333333331258.0TransmembraneHelical
TgeneABCB5chr17:29676269chr7:20671682ENST00000404938328181_20186.333333333333331258.0TransmembraneHelical
TgeneABCB5chr17:29676269chr7:20671682ENST00000404938328203_22386.333333333333331258.0TransmembraneHelical
TgeneABCB5chr17:29676269chr7:20671682ENST00000404938328294_31486.333333333333331258.0TransmembraneHelical
TgeneABCB5chr17:29676269chr7:20671682ENST00000404938328322_34286.333333333333331258.0TransmembraneHelical
TgeneABCB5chr17:29676269chr7:20671682ENST00000404938328693_71386.333333333333331258.0TransmembraneHelical
TgeneABCB5chr17:29676269chr7:20671682ENST00000404938328737_75786.333333333333331258.0TransmembraneHelical
TgeneABCB5chr17:29676269chr7:20671682ENST00000404938328827_84786.333333333333331258.0TransmembraneHelical
TgeneABCB5chr17:29676269chr7:20671682ENST00000404938328917_93786.333333333333331258.0TransmembraneHelical
TgeneABCB5chr17:29676269chr7:20671682ENST00000404938328954_97486.333333333333331258.0TransmembraneHelical
TgeneABCB5chr17:29676269chr7:20671682ENST0000040693506110_1300127.0TransmembraneHelical
TgeneABCB5chr17:29676269chr7:20671682ENST0000040693506181_2010127.0TransmembraneHelical
TgeneABCB5chr17:29676269chr7:20671682ENST0000040693506203_2230127.0TransmembraneHelical
TgeneABCB5chr17:29676269chr7:20671682ENST0000040693506294_3140127.0TransmembraneHelical
TgeneABCB5chr17:29676269chr7:20671682ENST0000040693506322_3420127.0TransmembraneHelical
TgeneABCB5chr17:29676269chr7:20671682ENST000004069350649_690127.0TransmembraneHelical
TgeneABCB5chr17:29676269chr7:20671682ENST0000040693506693_7130127.0TransmembraneHelical
TgeneABCB5chr17:29676269chr7:20671682ENST0000040693506737_7570127.0TransmembraneHelical
TgeneABCB5chr17:29676269chr7:20671682ENST0000040693506827_8470127.0TransmembraneHelical
TgeneABCB5chr17:29676269chr7:20671682ENST0000040693506917_9370127.0TransmembraneHelical
TgeneABCB5chr17:29676269chr7:20671682ENST0000040693506954_9740127.0TransmembraneHelical
TgeneABCB5chr17:29676269chr7:20671682ENST0000044302606110_1300132.0TransmembraneHelical
TgeneABCB5chr17:29676269chr7:20671682ENST0000044302606181_2010132.0TransmembraneHelical
TgeneABCB5chr17:29676269chr7:20671682ENST0000044302606203_2230132.0TransmembraneHelical
TgeneABCB5chr17:29676269chr7:20671682ENST0000044302606294_3140132.0TransmembraneHelical
TgeneABCB5chr17:29676269chr7:20671682ENST0000044302606322_3420132.0TransmembraneHelical
TgeneABCB5chr17:29676269chr7:20671682ENST000004430260649_690132.0TransmembraneHelical
TgeneABCB5chr17:29676269chr7:20671682ENST0000044302606693_7130132.0TransmembraneHelical
TgeneABCB5chr17:29676269chr7:20671682ENST0000044302606737_7570132.0TransmembraneHelical
TgeneABCB5chr17:29676269chr7:20671682ENST0000044302606827_8470132.0TransmembraneHelical
TgeneABCB5chr17:29676269chr7:20671682ENST0000044302606917_9370132.0TransmembraneHelical
TgeneABCB5chr17:29676269chr7:20671682ENST0000044302606954_9740132.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNF1chr17:29676269chr7:20671682ENST00000431387-1151352_13550594.0Compositional biasNote=Poly-Ser
HgeneNF1chr17:29676269chr7:20671682ENST00000431387-1151235_14510594.0DomainRas-GAP
HgeneNF1chr17:29676269chr7:20671682ENST00000431387-1151580_17380594.0DomainCRAL-TRIO
HgeneNF1chr17:29676269chr7:20671682ENST00000356175-48572555_25712419.33333333333352819.0MotifNote=Bipartite nuclear localization signal
HgeneNF1chr17:29676269chr7:20671682ENST00000358273-49582555_25712440.33333333333352840.0MotifNote=Bipartite nuclear localization signal
HgeneNF1chr17:29676269chr7:20671682ENST00000431387-1152555_25710594.0MotifNote=Bipartite nuclear localization signal
HgeneNF1chr17:29676269chr7:20671682ENST00000431387-1151580_18370594.0RegionNote=Lipid binding
TgeneABCB5chr17:29676269chr7:20671682ENST0000040493832849_35086.333333333333331258.0DomainABC transmembrane type-1 1
TgeneABCB5chr17:29676269chr7:20671682ENST0000040493832849_6986.333333333333331258.0TransmembraneHelical


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Fusion Gene Sequence for NF1-ABCB5


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000356175_ENST00000404938_TCGA-B6-A0I9-01A_NF1_chr17_29676269_-_ABCB5_chr7_20671682_length(transcript)=12541nt_BP=7641nt
AATCTCTAGCTCGCTCGCGCTCCCTCTCCCCGGGCCGTGGAAAGGATCCCACTTCCGGTGGGGTGTCATGGCGGCGTCTCGGACTGTGAT
GGCTGTGGGGAGACGGCGCTAGTGGGGAGAGCGACCAAGAGGCCCCCTCCCCTCCCCGGGTCCCCTTCCCCTATCCCCCTCCCCCCAGCC
TCCTTGCCAACGCCCCCTTTCCCTCTCCCCCTCCCGCTCGGCGCTGACCCCCCATCCCCACCCCCGTGGGAACACTGGGAGCCTGCACTC
CACAGACCCTCTCCTTGCCTCTTCCCTCACCTCAGCCTCCGCTCCCCGCCCTCTTCCCGGCCCAGGGCGCCGGCCCACCCTTCCCTCCGC
CGCCCCCCGGCCGCGGGGAGGACATGGCCGCGCACAGGCCGGTGGAATGGGTCCAGGCCGTGGTCAGCCGCTTCGACGAGCAGCTTCCAA
TAAAAACAGGACAGCAGAACACACATACCAAAGTCAGTACTGAGCACAACAAGGAATGTCTAATCAATATTTCCAAATACAAGTTTTCTT
TGGTTATAAGCGGCCTCACTACTATTTTAAAGAATGTTAACAATATGAGAATATTTGGAGAAGCTGCTGAAAAAAATTTATATCTCTCTC
AGTTGATTATATTGGATACACTGGAAAAATGTCTTGCTGGGCAACCAAAGGACACAATGAGATTAGATGAAACGATGCTGGTCAAACAGT
TGCTGCCAGAAATCTGCCATTTTCTTCACACCTGTCGTGAAGGAAACCAGCATGCAGCTGAACTTCGGAATTCTGCCTCTGGGGTTTTAT
TTTCTCTCAGCTGCAACAACTTCAATGCAGTCTTTAGTCGCATTTCTACCAGGTTACAGGAATTAACTGTTTGTTCAGAAGACAATGTTG
ATGTTCATGATATAGAATTGTTACAGTATATCAATGTGGATTGTGCAAAATTAAAACGACTCCTGAAGGAAACAGCATTTAAATTTAAAG
CCCTAAAGAAGGTTGCGCAGTTAGCAGTTATAAATAGCCTGGAAAAGGCATTTTGGAACTGGGTAGAAAATTATCCAGATGAATTTACAA
AACTGTACCAGATCCCACAGACTGATATGGCTGAATGTGCAGAAAAGCTATTTGACTTGGTGGATGGTTTTGCTGAAAGCACCAAACGTA
AAGCAGCAGTTTGGCCACTACAAATCATTCTCCTTATCTTGTGTCCAGAAATAATCCAGGATATATCCAAAGACGTGGTTGATGAAAACA
ACATGAATAAGAAGTTATTTCTGGACAGTCTACGAAAAGCTCTTGCTGGCCATGGAGGAAGTAGGCAGCTGACAGAAAGTGCTGCAATTG
CCTGTGTCAAACTGTGTAAAGCAAGTACTTACATCAATTGGGAAGATAACTCTGTCATTTTCCTACTTGTTCAGTCCATGGTGGTTGATC
TTAAGAACCTGCTTTTTAATCCAAGTAAGCCATTCTCAAGAGGCAGTCAGCCTGCAGATGTGGATCTAATGATTGACTGCCTTGTTTCTT
GCTTTCGTATAAGCCCTCACAACAACCAACACTTTAAGATCTGCCTGGCTCAGAATTCACCTTCTACATTTCACTATGTGCTGGTAAATT
CACTCCATCGAATCATCACCAATTCCGCATTGGATTGGTGGCCTAAGATTGATGCTGTGTATTGTCACTCGGTTGAACTTCGAAATATGT
TTGGTGAAACACTTCATAAAGCAGTGCAAGGTTGTGGAGCACACCCAGCAATACGAATGGCACCGAGTCTTACATTTAAAGAAAAAGTAA
CAAGCCTTAAATTTAAAGAAAAACCTACAGACCTGGAGACAAGAAGCTATAAGTATCTTCTCTTGTCCATGGTGAAACTAATTCATGCAG
ATCCAAAGCTCTTGCTTTGTAATCCAAGAAAACAGGGGCCCGAAACCCAAGGCAGTACAGCAGAATTAATTACAGGGCTCGTCCAACTGG
TCCCTCAGTCACACATGCCAGAGATTGCTCAGGAAGCAATGGAGGCTCTGCTGGTTCTTCATCAGTTAGATAGCATTGATTTGTGGAATC
CTGATGCTCCTGTAGAAACATTTTGGGAGATTAGCTCACAAATGCTTTTTTACATCTGCAAGAAATTAACTAGTCATCAAATGCTTAGTA
GCACAGAAATTCTCAAGTGGTTGCGGGAAATATTGATCTGCAGGAATAAATTTCTTCTTAAAAATAAGCAGGCAGATAGAAGTTCCTGTC
ACTTTCTCCTTTTTTACGGGGTAGGATGTGATATTCCTTCTAGTGGAAATACCAGTCAAATGTCCATGGATCATGAAGAATTACTACGTA
CTCCTGGAGCCTCTCTCCGGAAGGGAAAAGGGAACTCCTCTATGGATAGTGCAGCAGGATGCAGCGGAACCCCCCCGATTTGCCGACAAG
CCCAGACCAAACTAGAAGTGGCCCTGTACATGTTTCTGTGGAACCCTGACACTGAAGCTGTTCTGGTTGCCATGTCCTGTTTCCGCCACC
TCTGTGAGGAAGCAGATATCCGGTGTGGGGTGGATGAAGTGTCAGTGCATAACCTCTTGCCCAACTATAACACATTCATGGAGTTTGCCT
CTGTCAGCAATATGATGTCAACAGGAAGAGCAGCACTTCAGAAAAGAGTGATGGCACTGCTGAGGCGCATTGAGCATCCCACTGCAGGAA
ACACTGAGGCTTGGGAAGATACACATGCAAAATGGGAACAAGCAACAAAGCTAATCCTTAACTATCCAAAAGCCAAAATGGAAGATGGCC
AGGCTGCTGAAAGCCTTCACAAGACCATTGTTAAGAGGCGAATGTCCCATGTGAGTGGAGGAGGATCCATAGATTTGTCTGACACAGACT
CCCTACAGGAATGGATCAACATGACTGGCTTCCTTTGTGCCCTTGGGGGAGTGTGCCTCCAGCAGAGAAGCAATTCTGGCCTGGCAACCT
ATAGCCCACCCATGGGTCCAGTCAGTGAACGTAAGGGTTCTATGATTTCAGTGATGTCTTCAGAGGGAAACGCAGATACACCTGTCAGCA
AATTTATGGATCGGCTGTTGTCCTTAATGGTGTGTAACCATGAGAAAGTGGGACTTCAAATACGGACCAATGTTAAGGATCTGGTGGGTC
TAGAATTGAGTCCTGCTCTGTATCCAATGCTATTTAACAAATTGAAGAATACCATCAGCAAGTTTTTTGACTCCCAAGGACAGGTTTTAT
TGACTGATACCAATACTCAATTTGTAGAACAAACCATAGCTATAATGAAGAACTTGCTAGATAATCATACTGAAGGCAGCTCTGAACATC
TAGGGCAAGCTAGCATTGAAACAATGATGTTAAATCTGGTCAGGTATGTTCGTGTGCTTGGGAATATGGTCCATGCAATTCAAATAAAAA
CGAAACTGTGTCAATTAGTTGAAGTAATGATGGCAAGGAGAGATGACCTCTCATTTTGCCAAGAGATGAAATTTAGGAATAAGATGGTAG
AATACCTGACAGACTGGGTTATGGGAACATCAAACCAAGCAGCAGATGATGATGTAAAATGTCTTACAAGAGATTTGGACCAGGCAAGCA
TGGAAGCAGTAGTTTCACTTCTAGCTGGTCTCCCTCTGCAGCCTGAAGAAGGAGATGGTGTGGAATTGATGGAAGCCAAATCACAGTTAT
TTCTTAAATACTTCACATTATTTATGAACCTTTTGAATGACTGCAGTGAAGTTGAAGATGAAAGTGCGCAAACAGGTGGCAGGAAACGTG
GCATGTCTCGGAGGCTGGCATCACTGAGGCACTGTACGGTCCTTGCAATGTCAAACTTACTCAATGCCAACGTAGACAGTGGTCTCATGC
ACTCCATAGGCTTAGGTTACCACAAGGATCTCCAGACAAGAGCTACATTTATGGAAGTTCTGACAAAAATCCTTCAACAAGGCACAGAAT
TTGACACACTTGCAGAAACAGTATTGGCTGATCGGTTTGAGAGATTGGTGGAACTGGTCACAATGATGGGTGATCAAGGAGAACTCCCTA
TAGCGATGGCTCTGGCCAATGTGGTTCCTTGTTCTCAGTGGGATGAACTAGCTCGAGTTCTGGTTACTCTGTTTGATTCTCGGCATTTAC
TCTACCAACTGCTCTGGAACATGTTTTCTAAAGAAGTAGAATTGGCAGACTCCATGCAGACTCTCTTCCGAGGCAACAGCTTGGCCAGTA
AAATAATGACATTCTGTTTCAAGGTATATGGTGCTACCTATCTACAAAAACTCCTGGATCCTTTATTACGAATTGTGATCACATCCTCTG
ATTGGCAACATGTTAGCTTTGAAGTGGATCCTACCAGGTTAGAACCATCAGAGAGCCTTGAGGAAAACCAGCGGAACCTCCTTCAGATGA
CTGAAAAGTTCTTCCATGCCATCATCAGTTCCTCCTCAGAATTCCCCCCTCAACTTCGAAGTGTGTGCCACTGTTTATACCAGGTGGTTA
GCCAGCGTTTCCCTCAGAACAGCATCGGTGCAGTAGGAAGTGCCATGTTCCTCAGATTTATCAATCCTGCCATTGTCTCACCGTATGAAG
CAGGGATTTTAGATAAAAAGCCACCACCTAGAATCGAAAGGGGCTTGAAGTTAATGTCAAAGATACTTCAGAGTATTGCCAATCATGTTC
TCTTCACAAAAGAAGAACATATGCGGCCTTTCAATGATTTTGTGAAAAGCAACTTTGATGCAGCACGCAGGTTTTTCCTTGATATAGCAT
CTGATTGTCCTACAAGTGATGCAGTAAATCATAGTCTTTCCTTCATAAGTGACGGCAATGTGCTTGCTTTACATCGTCTACTCTGGAACA
ATCAGGAGAAAATTGGGCAGTATCTTTCCAGCAACAGGGATCATAAAGCTGTTGGAAGACGACCTTTTGATAAGATGGCAACACTTCTTG
CATACCTGGGTCCTCCAGAGCACAAACCTGTGGCAGATACACACTGGTCCAGCCTTAACCTTACCAGTTCAAAGTTTGAGGAATTTATGA
CTAGGCATCAGGTACATGAAAAAGAAGAATTCAAGGCTTTGAAAACGTTAAGTATTTTCTACCAAGCTGGGACTTCCAAAGCTGGGAATC
CTATTTTTTATTATGTTGCACGGAGGTTCAAAACTGGTCAAATCAATGGTGATTTGCTGATATACCATGTCTTACTGACTTTAAAGCCAT
ATTATGCAAAGCCATATGAAATTGTAGTGGACCTTACCCATACCGGGCCTAGCAATCGCTTTAAAACAGACTTTCTCTCTAAGTGGTTTG
TTGTTTTTCCTGGCTTTGCTTACGACAACGTCTCCGCAGTCTATATCTATAACTGTAACTCCTGGGTCAGGGAGTACACCAAGTATCATG
AGCGGCTGCTGACTGGCCTCAAAGGTAGCAAAAGGCTTGTTTTCATAGACTGTCCTGGGAAACTGGCTGAGCACATAGAGCATGAACAAC
AGAAACTACCTGCTGCCACCTTGGCTTTAGAAGAGGACCTGAAGGTATTCCACAATGCTCTCAAGCTAGCTCACAAAGACACCAAAGTTT
CTATTAAAGTTGGTTCTACTGCTGTCCAAGTAACTTCAGCAGAGCGAACAAAAGTCCTAGGGCAATCAGTCTTTCTAAATGACATTTATT
ATGCTTCGGAAATTGAAGAAATCTGCCTAGTAGATGAGAACCAGTTCACCTTAACCATTGCAAACCAGGGCACGCCGCTCACCTTCATGC
ACCAGGAGTGTGAAGCCATTGTCCAGTCTATCATTCATATCCGGACCCGCTGGGAACTGTCACAGCCCGACTCTATCCCCCAACACACCA
AGATTCGGCCAAAAGATGTCCCTGGGACACTGCTCAATATCGCATTACTTAATTTAGGCAGTTCTGACCCGAGTTTACGGTCAGCTGCCT
ATAATCTTCTGTGTGCCTTAACTTGTACCTTTAATTTAAAAATCGAGGGCCAGTTACTAGAGACATCAGGTTTATGTATCCCTGCCAACA
ACACCCTCTTTATTGTCTCTATTAGTAAGACACTGGCAGCCAATGAGCCACACCTCACGTTAGAATTTTTGGAAGAGTGTATTTCTGGAT
TTAGCAAATCTAGTATTGAATTGAAACACCTTTGTTTGGAATACATGACTCCATGGCTGTCAAATCTAGTTCGTTTTTGCAAGCATAATG
ATGATGCCAAACGACAAAGAGTTACTGCTATTCTTGACAAGCTGATAACAATGACCATCAATGAAAAACAGATGTACCCATCTATTCAAG
CAAAAATATGGGGAAGCCTTGGGCAGATTACAGATCTGCTTGATGTTGTACTAGACAGTTTCATCAAAACCAGTGCAACAGGTGGCTTGG
GATCAATAAAAGCTGAGGTGATGGCAGATACTGCTGTAGCTTTGGCTTCTGGAAATGTGAAATTGGTTTCAAGCAAGGTTATTGGAAGGA
TGTGCAAAATAATTGACAAGACATGCTTATCTCCAACTCCTACTTTAGAACAACATCTTATGTGGGATGATATTGCTATTTTAGCACGCT
ACATGCTGATGCTGTCCTTCAACAATTCCCTTGATGTGGCAGCTCATCTTCCCTACCTCTTCCACGTTGTTACTTTCTTAGTAGCCACAG
GTCCGCTCTCCCTTAGAGCTTCCACACATGGACTGGTCATTAATATCATTCACTCTCTGTGTACTTGTTCACAGCTTCATTTTAGTGAAG
AGACCAAGCAAGTTTTGAGACTCAGTCTGACAGAGTTCTCATTACCCAAATTTTACTTGCTGTTTGGCATTAGCAAAGTCAAGTCAGCTG
CTGTCATTGCCTTCCGTTCCAGTTACCGGGACAGGTCATTCTCTCCTGGCTCCTATGAGAGAGAGACTTTTGCTTTGACATCCTTGGAAA
CAGTCACAGAAGCTTTGTTGGAGATCATGGAGGCATGCATGAGAGATATTCCAACGTGCAAGTGGCTGGACCAGTGGACAGAACTAGCTC
AAAGATTTGCATTCCAATATAATCCATCCCTGCAACCAAGAGCTCTTGTTGTCTTTGGGTGTATTAGCAAACGAGTGTCTCATGGGCAGA
TAAAGCAGATAATCCGTATTCTTAGCAAGGCACTTGAGAGTTGCTTAAAAGGACCTGACACTTACAACAGTCAAGTTCTGATAGAAGCTA
CAGTAATAGCACTAACCAAATTACAGCCACTTCTTAATAAGGACTCGCCTCTGCACAAAGCCCTCTTTTGGGTAGCTGTGGCTGTGCTGC
AGCTTGATGAGGTCAACTTGTATTCAGCAGGTACCGCACTTCTTGAACAAAACCTGCATACTTTAGATAGTCTCCGTATATTCAATGACA
AGAGTCCAGAGGAAGTATTTATGGCAATCCGGAATCCTCTGGAGTGGCACTGCAAGCAAATGGATCATTTTGTTGGACTCAATTTCAACT
CTAACTTTAACTTTGCATTGGTTGGACACCTTTTAAAAGGGTACAGGCATCCTTCACCTGCTATTGTTGCAAGAACAGTCAGAATTTTAC
ATACACTACTAACTCTGGTTAACAAACACAGAAATTGTGACAAATTTGAAGTGAATACACAGAGCGTGGCCTACTTAGCAGCAAATTATC
AGAACTGTACTCAGTCTCAAGAGAAGCTGAATGAAGATATGACTCTGTTGACCCTGTATTATGTTGGAATAGGTGTTGCTGCCTTGATTT
TTGGTTACATACAGATTTCCTTGTGGATTATAACTGCAGCACGACAGACCAAGAGGATTCGAAAACAGTTTTTTCATTCAGTTTTGGCAC
AGGACATCGGCTGGTTTGATAGCTGTGACATCGGTGAACTTAACACTCGCATGACAGATGACATTGACAAAATCAGTGATGGTATTGGAG
ATAAGATTGCTCTGTTGTTTCAAAACATGTCTACTTTTTCGATTGGCCTGGCAGTTGGTTTGGTGAAGGGCTGGAAACTCACCCTAGTGA
CTCTATCCACGTCTCCTCTTATAATGGCTTCAGCGGCAGCATGTTCTAGGATGGTCATCTCATTGACCAGTAAGGAATTAAGTGCCTATT
CCAAAGCTGGGGCTGTGGCAGAAGAAGTCTTGTCATCAATCCGAACAGTCATAGCCTTTAGGGCCCAGGAGAAAGAACTTCAAAGGTATA
CACAGAATCTCAAAGATGCAAAGGATTTTGGCATAAAAAGGACTATAGCTTCAAAAGTGTCTCTTGGTGCTGTGTACTTCTTTATGAATG
GAACCTATGGACTTGCTTTTTGGTATGGAACCTCCTTGATTCTTAATGGAGAACCTGGATATACCATCGGGACTGTTCTTGCTGTTTTCT
TTAGTGTAATCCATAGCAGTTATTGCATTGGAGCAGCAGTCCCTCACTTTGAAACCTTCGCAATAGCCCGAGGAGCTGCCTTTCATATTT
TCCAGGTTATTGATAAGAAACCCAGTATAGATAACTTTTCCACAGCTGGATATAAACCTGAATCCATAGAAGGAACTGTGGAATTTAAAA
ATGTTTCTTTCAATTATCCATCAAGACCATCTATCAAGATTCTGAAAGGTCTGAATCTCAGAATTAAGTCTGGAGAGACAGTCGCCTTGG
TCGGTCTCAATGGCAGTGGGAAGAGTACGGTAGTCCAGCTTCTGCAGAGGTTATATGATCCGGATGATGGCTTTATCATGGTGGATGAGA
ATGACATCAGAGCTTTAAATGTGCGGCATTATCGAGACCATATTGGAGTGGTTAGTCAAGAGCCTGTTTTGTTCGGGACCACCATCAGTA
ACAATATCAAGTATGGACGAGATGATGTGACTGATGAAGAGATGGAGAGAGCAGCAAGGGAAGCAAATGCGTATGATTTTATCATGGAGT
TTCCTAATAAATTTAATACATTGGTAGGGGAAAAAGGAGCTCAAATGAGTGGAGGGCAGAAACAGAGGATCGCAATTGCTCGTGCCTTAG
TTCGAAACCCCAAGATTCTGATTTTAGATGAGGCTACGTCTGCCCTGGATTCAGAAAGCAAGTCAGCTGTTCAAGCTGCACTGGAGAAGG
CGAGCAAAGGTCGGACTACAATCGTGGTAGCACACCGACTTTCTACTATTCGAAGTGCAGATTTGATTGTGACCCTAAAGGATGGAATGC
TGGCGGAGAAAGGAGCACATGCTGAACTAATGGCAAAACGAGGTCTATATTATTCACTTGTGATGTCACAGGATATTAAAAAAGCTGATG
AACAGATGGAGTCAATGACATATTCTACTGAAAGAAAGACCAACTCACTTCCTCTGCACTCTGTGAAGAGCATCAAGTCAGACTTCATTG
ACAAGGCTGAGGAATCCACCCAATCTAAAGAGATAAGTCTTCCTGAAGTCTCTCTATTAAAAATTTTAAAGTTAAACAAGCCTGAATGGC
CTTTTGTGGTTCTGGGGACATTGGCTTCTGTTCTAAATGGAACTGTTCATCCAGTATTTTCCATCATCTTTGCAAAAATTATAACCATGT
TTGGAAATAATGATAAAACCACATTAAAGCATGATGCAGAAATTTATTCCATGATATTCGTCATTTTGGGTGTTATTTGCTTTGTCAGTT
ATTTCATGCAGGGATTATTTTACGGCAGAGCAGGGGAAATTTTAACGATGAGATTAAGACACTTGGCCTTCAAAGCCATGTTATATCAGG
ATATTGCCTGGTTTGATGAAAAGGAAAACAGCACAGGAGGCTTGACAACAATATTAGCCATAGATATAGCACAAATTCAAGGAGCAACAG
GTTCCAGGATTGGCGTCTTAACACAAAATGCAACTAACATGGGACTTTCAGTTATCATTTCCTTTATATATGGATGGGAGATGACATTCC
TGATTCTGAGTATTGCTCCAGTACTTGCCGTGACAGGAATGATTGAAACCGCAGCAATGACTGGATTTGCCAACAAAGATAAGCAAGAAC
TTAAGCATGCTGGAAAGATAGCAACTGAAGCTTTGGAGAATATACGTACTATAGTGTCATTAACAAGGGAAAAAGCCTTCGAGCAAATGT
ATGAAGAGATGCTTCAGACTCAACACAGAAATACCTCGAAGAAAGCACAGATTATTGGAAGCTGTTATGCATTCAGCCATGCCTTTATAT
ATTTTGCCTATGCGGCAGGGTTTCGATTTGGAGCCTATTTAATTCAAGCTGGACGAATGACCCCAGAGGGCATGTTCATAGTTTTTACTG
CAATTGCATATGGAGCTATGGCCATCGGAGAAACGCTCGTTTTGGCTCCTGAATATTCCAAAGCCAAATCGGGGGCTGCGCATCTGTTTG
CCTTGTTGGAAAAGAAACCAAATATAGACAGCCGCAGTCAAGAAGGGAAAAAGCCAGACACATGTGAAGGGAATTTAGAGTTTCGAGAAG
TCTCTTTCTTCTATCCATGTCGCCCAGATGTTTTCATCCTCCGTGGCTTATCCCTCAGTATTGAGCGAGGAAAGACAGTAGCATTTGTGG
GGAGCAGCGGCTGTGGGAAAAGCACTTCTGTTCAACTTCTGCAGAGACTTTATGACCCCGTGCAAGGACAAGTGCTGTTTGATGGTGTGG
ATGCAAAAGAATTGAATGTACAGTGGCTCCGTTCCCAAATAGCAATCGTTCCTCAAGAGCCTGTGCTCTTCAACTGCAGCATTGCTGAGA
ACATCGCCTATGGTGACAACAGCCGTGTGGTGCCATTAGATGAGATCAAAGAAGCCGCAAATGCAGCAAATATCCATTCTTTTATTGAAG
GTCTCCCTGAGAAATACAACACACAAGTTGGACTGAAAGGAGCACAGCTTTCTGGCGGCCAGAAACAAAGACTAGCTATTGCAAGGGCTC
TTCTCCAAAAACCCAAAATTTTATTGTTGGATGAGGCCACTTCAGCCCTCGATAATGACAGTGAGAAGGTGGTTCAGCATGCCCTTGATA
AAGCCAGGACGGGAAGGACATGCCTAGTGGTCACTCACAGGCTCTCTGCAATTCAGAACGCAGATTTGATAGTGGTTCTGCACAATGGAA
AGATAAAGGAACAAGGAACTCATCAAGAGCTCCTGAGAAATCGAGACATATATTTTAAGTTAGTGAATGCACAGTCAGTGCAGTGATGCT
GTTGAGGTAGCACATATTTTGATGTTCGTGTAATGCAAAGAAGGAGTACTTAATAATTACTTGGCAAGCTTTGATCTCTTTTATTGCATA
TATCAATACCTAGAATCATGCTACTCAAGTACATACATGTTCTATTCACACACCATCTGACCTTCAGATTTTTAAAAGGAAGCAAAAATT
TGCTTATTTCATGTAAGTGAAATAATGCTTATATCCTTCACTTTATAAAACTATTCTAGCACATTTGCTTGTAAAGCAGTTTTCTACAAG
GTGAATTTATTTCCCATCAACTTCTGCTATAAAATCGGAAATATGTTTCCAGGGGGAATATTATCCAATTAACCATGTTGAAGGTTTTAG
CAAAGGCAGTGTAAGATAGAGTGGGGCCTGTAGCATTGCAGGGAGAGTGTCTTTCACTTGGAATTTTGTTTTGCAGCACATATTACAGTA
GTTTTGCTAGTCCCTTTTCTCCAGACCGTAGGGATTTCTCTCAATAAGTATTCACTATTTCTCTAAATTTTATTCTATTTTTTTGTTGAG
CAGGGAATAGAAAGGATTACGATGTAAAATTTCTGGGAGGATTAGGTAGCTATCTCCTACTTCACCAGTAAGTGAAGTGCCTCACATGAG
CCATCCCAAAGATTCATTATTCCAAACCTTGGGTTTGGCAGTATAAGTCACAGGCCTACCTGTTTATGAAAACTTACTTACTTAAAATAA
GAGCTACTTTTGGGCCGGGTGCGGTGGCTCACGCCTGTAATCCCAGAACTTTGGGAGGCCGAGGAGGGCGGATCACTTGAGGTCAGGAGT
TCGAGACCAGCCTGGCCAACATGGTGAAACCCCGTCTCTACTAAAAACACAAAAATTAGCCAATCTTGGTGGCGGGCACCTGGAATCCCA
GCTACTTGGGAGGCTGAGGCAGGAGAATCATTTGAACCTAGGAGGCAGAGGTTGCAGTGAGCCGAGATCTCACCACTGCACTCCAGCCTG
CGCAACAGAGCGAGACTCCATCTCAAAAAATAATAAATAAGAGCTAATTTTATTGTGGGTGAAAATTTTTAAACGTCTTTCTCTATAATA
AAATAATTTCCTTAAATTTTATATATACTTTATCATATATAATGTGTGAATGATTTTAAAGTTCTGTGTAAATAACAATATTGGTAAAAT
GAGTTACATTTTCAACTTACTTAAATATGTAATGTCACCTGGTGATTTTATCTTTATTCTTCAGTGTATTTTCTTCCATTTACACATTTA
GCTAGCCTCCCTAAAGTGTACTCTACCAATAATTGAAATCTTGTTAAACAAAATTAAAACCATTTATATATTATGCTGCTTTCTTTAAAA

>In-frame_ENST00000356175_ENST00000404938_TCGA-B6-A0I9-01A_NF1_chr17_29676269_-_ABCB5_chr7_20671682_length(amino acids)=3633AA_start in transcript=254_stop in transcript=11155
MGACTPQTLSLPLPSPQPPLPALFPAQGAGPPFPPPPPGRGEDMAAHRPVEWVQAVVSRFDEQLPIKTGQQNTHTKVSTEHNKECLINIS
KYKFSLVISGLTTILKNVNNMRIFGEAAEKNLYLSQLIILDTLEKCLAGQPKDTMRLDETMLVKQLLPEICHFLHTCREGNQHAAELRNS
ASGVLFSLSCNNFNAVFSRISTRLQELTVCSEDNVDVHDIELLQYINVDCAKLKRLLKETAFKFKALKKVAQLAVINSLEKAFWNWVENY
PDEFTKLYQIPQTDMAECAEKLFDLVDGFAESTKRKAAVWPLQIILLILCPEIIQDISKDVVDENNMNKKLFLDSLRKALAGHGGSRQLT
ESAAIACVKLCKASTYINWEDNSVIFLLVQSMVVDLKNLLFNPSKPFSRGSQPADVDLMIDCLVSCFRISPHNNQHFKICLAQNSPSTFH
YVLVNSLHRIITNSALDWWPKIDAVYCHSVELRNMFGETLHKAVQGCGAHPAIRMAPSLTFKEKVTSLKFKEKPTDLETRSYKYLLLSMV
KLIHADPKLLLCNPRKQGPETQGSTAELITGLVQLVPQSHMPEIAQEAMEALLVLHQLDSIDLWNPDAPVETFWEISSQMLFYICKKLTS
HQMLSSTEILKWLREILICRNKFLLKNKQADRSSCHFLLFYGVGCDIPSSGNTSQMSMDHEELLRTPGASLRKGKGNSSMDSAAGCSGTP
PICRQAQTKLEVALYMFLWNPDTEAVLVAMSCFRHLCEEADIRCGVDEVSVHNLLPNYNTFMEFASVSNMMSTGRAALQKRVMALLRRIE
HPTAGNTEAWEDTHAKWEQATKLILNYPKAKMEDGQAAESLHKTIVKRRMSHVSGGGSIDLSDTDSLQEWINMTGFLCALGGVCLQQRSN
SGLATYSPPMGPVSERKGSMISVMSSEGNADTPVSKFMDRLLSLMVCNHEKVGLQIRTNVKDLVGLELSPALYPMLFNKLKNTISKFFDS
QGQVLLTDTNTQFVEQTIAIMKNLLDNHTEGSSEHLGQASIETMMLNLVRYVRVLGNMVHAIQIKTKLCQLVEVMMARRDDLSFCQEMKF
RNKMVEYLTDWVMGTSNQAADDDVKCLTRDLDQASMEAVVSLLAGLPLQPEEGDGVELMEAKSQLFLKYFTLFMNLLNDCSEVEDESAQT
GGRKRGMSRRLASLRHCTVLAMSNLLNANVDSGLMHSIGLGYHKDLQTRATFMEVLTKILQQGTEFDTLAETVLADRFERLVELVTMMGD
QGELPIAMALANVVPCSQWDELARVLVTLFDSRHLLYQLLWNMFSKEVELADSMQTLFRGNSLASKIMTFCFKVYGATYLQKLLDPLLRI
VITSSDWQHVSFEVDPTRLEPSESLEENQRNLLQMTEKFFHAIISSSSEFPPQLRSVCHCLYQVVSQRFPQNSIGAVGSAMFLRFINPAI
VSPYEAGILDKKPPPRIERGLKLMSKILQSIANHVLFTKEEHMRPFNDFVKSNFDAARRFFLDIASDCPTSDAVNHSLSFISDGNVLALH
RLLWNNQEKIGQYLSSNRDHKAVGRRPFDKMATLLAYLGPPEHKPVADTHWSSLNLTSSKFEEFMTRHQVHEKEEFKALKTLSIFYQAGT
SKAGNPIFYYVARRFKTGQINGDLLIYHVLLTLKPYYAKPYEIVVDLTHTGPSNRFKTDFLSKWFVVFPGFAYDNVSAVYIYNCNSWVRE
YTKYHERLLTGLKGSKRLVFIDCPGKLAEHIEHEQQKLPAATLALEEDLKVFHNALKLAHKDTKVSIKVGSTAVQVTSAERTKVLGQSVF
LNDIYYASEIEEICLVDENQFTLTIANQGTPLTFMHQECEAIVQSIIHIRTRWELSQPDSIPQHTKIRPKDVPGTLLNIALLNLGSSDPS
LRSAAYNLLCALTCTFNLKIEGQLLETSGLCIPANNTLFIVSISKTLAANEPHLTLEFLEECISGFSKSSIELKHLCLEYMTPWLSNLVR
FCKHNDDAKRQRVTAILDKLITMTINEKQMYPSIQAKIWGSLGQITDLLDVVLDSFIKTSATGGLGSIKAEVMADTAVALASGNVKLVSS
KVIGRMCKIIDKTCLSPTPTLEQHLMWDDIAILARYMLMLSFNNSLDVAAHLPYLFHVVTFLVATGPLSLRASTHGLVINIIHSLCTCSQ
LHFSEETKQVLRLSLTEFSLPKFYLLFGISKVKSAAVIAFRSSYRDRSFSPGSYERETFALTSLETVTEALLEIMEACMRDIPTCKWLDQ
WTELAQRFAFQYNPSLQPRALVVFGCISKRVSHGQIKQIIRILSKALESCLKGPDTYNSQVLIEATVIALTKLQPLLNKDSPLHKALFWV
AVAVLQLDEVNLYSAGTALLEQNLHTLDSLRIFNDKSPEEVFMAIRNPLEWHCKQMDHFVGLNFNSNFNFALVGHLLKGYRHPSPAIVAR
TVRILHTLLTLVNKHRNCDKFEVNTQSVAYLAANYQNCTQSQEKLNEDMTLLTLYYVGIGVAALIFGYIQISLWIITAARQTKRIRKQFF
HSVLAQDIGWFDSCDIGELNTRMTDDIDKISDGIGDKIALLFQNMSTFSIGLAVGLVKGWKLTLVTLSTSPLIMASAAACSRMVISLTSK
ELSAYSKAGAVAEEVLSSIRTVIAFRAQEKELQRYTQNLKDAKDFGIKRTIASKVSLGAVYFFMNGTYGLAFWYGTSLILNGEPGYTIGT
VLAVFFSVIHSSYCIGAAVPHFETFAIARGAAFHIFQVIDKKPSIDNFSTAGYKPESIEGTVEFKNVSFNYPSRPSIKILKGLNLRIKSG
ETVALVGLNGSGKSTVVQLLQRLYDPDDGFIMVDENDIRALNVRHYRDHIGVVSQEPVLFGTTISNNIKYGRDDVTDEEMERAAREANAY
DFIMEFPNKFNTLVGEKGAQMSGGQKQRIAIARALVRNPKILILDEATSALDSESKSAVQAALEKASKGRTTIVVAHRLSTIRSADLIVT
LKDGMLAEKGAHAELMAKRGLYYSLVMSQDIKKADEQMESMTYSTERKTNSLPLHSVKSIKSDFIDKAEESTQSKEISLPEVSLLKILKL
NKPEWPFVVLGTLASVLNGTVHPVFSIIFAKIITMFGNNDKTTLKHDAEIYSMIFVILGVICFVSYFMQGLFYGRAGEILTMRLRHLAFK
AMLYQDIAWFDEKENSTGGLTTILAIDIAQIQGATGSRIGVLTQNATNMGLSVIISFIYGWEMTFLILSIAPVLAVTGMIETAAMTGFAN
KDKQELKHAGKIATEALENIRTIVSLTREKAFEQMYEEMLQTQHRNTSKKAQIIGSCYAFSHAFIYFAYAAGFRFGAYLIQAGRMTPEGM
FIVFTAIAYGAMAIGETLVLAPEYSKAKSGAAHLFALLEKKPNIDSRSQEGKKPDTCEGNLEFREVSFFYPCRPDVFILRGLSLSIERGK
TVAFVGSSGCGKSTSVQLLQRLYDPVQGQVLFDGVDAKELNVQWLRSQIAIVPQEPVLFNCSIAENIAYGDNSRVVPLDEIKEAANAANI
HSFIEGLPEKYNTQVGLKGAQLSGGQKQRLAIARALLQKPKILLLDEATSALDNDSEKVVQHALDKARTGRTCLVVTHRLSAIQNADLIV

--------------------------------------------------------------
>In-frame_ENST00000358273_ENST00000404938_TCGA-B6-A0I9-01A_NF1_chr17_29676269_-_ABCB5_chr7_20671682_length(transcript)=12604nt_BP=7704nt
AATCTCTAGCTCGCTCGCGCTCCCTCTCCCCGGGCCGTGGAAAGGATCCCACTTCCGGTGGGGTGTCATGGCGGCGTCTCGGACTGTGAT
GGCTGTGGGGAGACGGCGCTAGTGGGGAGAGCGACCAAGAGGCCCCCTCCCCTCCCCGGGTCCCCTTCCCCTATCCCCCTCCCCCCAGCC
TCCTTGCCAACGCCCCCTTTCCCTCTCCCCCTCCCGCTCGGCGCTGACCCCCCATCCCCACCCCCGTGGGAACACTGGGAGCCTGCACTC
CACAGACCCTCTCCTTGCCTCTTCCCTCACCTCAGCCTCCGCTCCCCGCCCTCTTCCCGGCCCAGGGCGCCGGCCCACCCTTCCCTCCGC
CGCCCCCCGGCCGCGGGGAGGACATGGCCGCGCACAGGCCGGTGGAATGGGTCCAGGCCGTGGTCAGCCGCTTCGACGAGCAGCTTCCAA
TAAAAACAGGACAGCAGAACACACATACCAAAGTCAGTACTGAGCACAACAAGGAATGTCTAATCAATATTTCCAAATACAAGTTTTCTT
TGGTTATAAGCGGCCTCACTACTATTTTAAAGAATGTTAACAATATGAGAATATTTGGAGAAGCTGCTGAAAAAAATTTATATCTCTCTC
AGTTGATTATATTGGATACACTGGAAAAATGTCTTGCTGGGCAACCAAAGGACACAATGAGATTAGATGAAACGATGCTGGTCAAACAGT
TGCTGCCAGAAATCTGCCATTTTCTTCACACCTGTCGTGAAGGAAACCAGCATGCAGCTGAACTTCGGAATTCTGCCTCTGGGGTTTTAT
TTTCTCTCAGCTGCAACAACTTCAATGCAGTCTTTAGTCGCATTTCTACCAGGTTACAGGAATTAACTGTTTGTTCAGAAGACAATGTTG
ATGTTCATGATATAGAATTGTTACAGTATATCAATGTGGATTGTGCAAAATTAAAACGACTCCTGAAGGAAACAGCATTTAAATTTAAAG
CCCTAAAGAAGGTTGCGCAGTTAGCAGTTATAAATAGCCTGGAAAAGGCATTTTGGAACTGGGTAGAAAATTATCCAGATGAATTTACAA
AACTGTACCAGATCCCACAGACTGATATGGCTGAATGTGCAGAAAAGCTATTTGACTTGGTGGATGGTTTTGCTGAAAGCACCAAACGTA
AAGCAGCAGTTTGGCCACTACAAATCATTCTCCTTATCTTGTGTCCAGAAATAATCCAGGATATATCCAAAGACGTGGTTGATGAAAACA
ACATGAATAAGAAGTTATTTCTGGACAGTCTACGAAAAGCTCTTGCTGGCCATGGAGGAAGTAGGCAGCTGACAGAAAGTGCTGCAATTG
CCTGTGTCAAACTGTGTAAAGCAAGTACTTACATCAATTGGGAAGATAACTCTGTCATTTTCCTACTTGTTCAGTCCATGGTGGTTGATC
TTAAGAACCTGCTTTTTAATCCAAGTAAGCCATTCTCAAGAGGCAGTCAGCCTGCAGATGTGGATCTAATGATTGACTGCCTTGTTTCTT
GCTTTCGTATAAGCCCTCACAACAACCAACACTTTAAGATCTGCCTGGCTCAGAATTCACCTTCTACATTTCACTATGTGCTGGTAAATT
CACTCCATCGAATCATCACCAATTCCGCATTGGATTGGTGGCCTAAGATTGATGCTGTGTATTGTCACTCGGTTGAACTTCGAAATATGT
TTGGTGAAACACTTCATAAAGCAGTGCAAGGTTGTGGAGCACACCCAGCAATACGAATGGCACCGAGTCTTACATTTAAAGAAAAAGTAA
CAAGCCTTAAATTTAAAGAAAAACCTACAGACCTGGAGACAAGAAGCTATAAGTATCTTCTCTTGTCCATGGTGAAACTAATTCATGCAG
ATCCAAAGCTCTTGCTTTGTAATCCAAGAAAACAGGGGCCCGAAACCCAAGGCAGTACAGCAGAATTAATTACAGGGCTCGTCCAACTGG
TCCCTCAGTCACACATGCCAGAGATTGCTCAGGAAGCAATGGAGGCTCTGCTGGTTCTTCATCAGTTAGATAGCATTGATTTGTGGAATC
CTGATGCTCCTGTAGAAACATTTTGGGAGATTAGCTCACAAATGCTTTTTTACATCTGCAAGAAATTAACTAGTCATCAAATGCTTAGTA
GCACAGAAATTCTCAAGTGGTTGCGGGAAATATTGATCTGCAGGAATAAATTTCTTCTTAAAAATAAGCAGGCAGATAGAAGTTCCTGTC
ACTTTCTCCTTTTTTACGGGGTAGGATGTGATATTCCTTCTAGTGGAAATACCAGTCAAATGTCCATGGATCATGAAGAATTACTACGTA
CTCCTGGAGCCTCTCTCCGGAAGGGAAAAGGGAACTCCTCTATGGATAGTGCAGCAGGATGCAGCGGAACCCCCCCGATTTGCCGACAAG
CCCAGACCAAACTAGAAGTGGCCCTGTACATGTTTCTGTGGAACCCTGACACTGAAGCTGTTCTGGTTGCCATGTCCTGTTTCCGCCACC
TCTGTGAGGAAGCAGATATCCGGTGTGGGGTGGATGAAGTGTCAGTGCATAACCTCTTGCCCAACTATAACACATTCATGGAGTTTGCCT
CTGTCAGCAATATGATGTCAACAGGAAGAGCAGCACTTCAGAAAAGAGTGATGGCACTGCTGAGGCGCATTGAGCATCCCACTGCAGGAA
ACACTGAGGCTTGGGAAGATACACATGCAAAATGGGAACAAGCAACAAAGCTAATCCTTAACTATCCAAAAGCCAAAATGGAAGATGGCC
AGGCTGCTGAAAGCCTTCACAAGACCATTGTTAAGAGGCGAATGTCCCATGTGAGTGGAGGAGGATCCATAGATTTGTCTGACACAGACT
CCCTACAGGAATGGATCAACATGACTGGCTTCCTTTGTGCCCTTGGGGGAGTGTGCCTCCAGCAGAGAAGCAATTCTGGCCTGGCAACCT
ATAGCCCACCCATGGGTCCAGTCAGTGAACGTAAGGGTTCTATGATTTCAGTGATGTCTTCAGAGGGAAACGCAGATACACCTGTCAGCA
AATTTATGGATCGGCTGTTGTCCTTAATGGTGTGTAACCATGAGAAAGTGGGACTTCAAATACGGACCAATGTTAAGGATCTGGTGGGTC
TAGAATTGAGTCCTGCTCTGTATCCAATGCTATTTAACAAATTGAAGAATACCATCAGCAAGTTTTTTGACTCCCAAGGACAGGTTTTAT
TGACTGATACCAATACTCAATTTGTAGAACAAACCATAGCTATAATGAAGAACTTGCTAGATAATCATACTGAAGGCAGCTCTGAACATC
TAGGGCAAGCTAGCATTGAAACAATGATGTTAAATCTGGTCAGGTATGTTCGTGTGCTTGGGAATATGGTCCATGCAATTCAAATAAAAA
CGAAACTGTGTCAATTAGTTGAAGTAATGATGGCAAGGAGAGATGACCTCTCATTTTGCCAAGAGATGAAATTTAGGAATAAGATGGTAG
AATACCTGACAGACTGGGTTATGGGAACATCAAACCAAGCAGCAGATGATGATGTAAAATGTCTTACAAGAGATTTGGACCAGGCAAGCA
TGGAAGCAGTAGTTTCACTTCTAGCTGGTCTCCCTCTGCAGCCTGAAGAAGGAGATGGTGTGGAATTGATGGAAGCCAAATCACAGTTAT
TTCTTAAATACTTCACATTATTTATGAACCTTTTGAATGACTGCAGTGAAGTTGAAGATGAAAGTGCGCAAACAGGTGGCAGGAAACGTG
GCATGTCTCGGAGGCTGGCATCACTGAGGCACTGTACGGTCCTTGCAATGTCAAACTTACTCAATGCCAACGTAGACAGTGGTCTCATGC
ACTCCATAGGCTTAGGTTACCACAAGGATCTCCAGACAAGAGCTACATTTATGGAAGTTCTGACAAAAATCCTTCAACAAGGCACAGAAT
TTGACACACTTGCAGAAACAGTATTGGCTGATCGGTTTGAGAGATTGGTGGAACTGGTCACAATGATGGGTGATCAAGGAGAACTCCCTA
TAGCGATGGCTCTGGCCAATGTGGTTCCTTGTTCTCAGTGGGATGAACTAGCTCGAGTTCTGGTTACTCTGTTTGATTCTCGGCATTTAC
TCTACCAACTGCTCTGGAACATGTTTTCTAAAGAAGTAGAATTGGCAGACTCCATGCAGACTCTCTTCCGAGGCAACAGCTTGGCCAGTA
AAATAATGACATTCTGTTTCAAGGTATATGGTGCTACCTATCTACAAAAACTCCTGGATCCTTTATTACGAATTGTGATCACATCCTCTG
ATTGGCAACATGTTAGCTTTGAAGTGGATCCTACCAGGTTAGAACCATCAGAGAGCCTTGAGGAAAACCAGCGGAACCTCCTTCAGATGA
CTGAAAAGTTCTTCCATGCCATCATCAGTTCCTCCTCAGAATTCCCCCCTCAACTTCGAAGTGTGTGCCACTGTTTATACCAGGCAACTT
GCCACTCCCTACTGAATAAAGCTACAGTAAAAGAAAAAAAGGAAAACAAAAAATCAGTGGTTAGCCAGCGTTTCCCTCAGAACAGCATCG
GTGCAGTAGGAAGTGCCATGTTCCTCAGATTTATCAATCCTGCCATTGTCTCACCGTATGAAGCAGGGATTTTAGATAAAAAGCCACCAC
CTAGAATCGAAAGGGGCTTGAAGTTAATGTCAAAGATACTTCAGAGTATTGCCAATCATGTTCTCTTCACAAAAGAAGAACATATGCGGC
CTTTCAATGATTTTGTGAAAAGCAACTTTGATGCAGCACGCAGGTTTTTCCTTGATATAGCATCTGATTGTCCTACAAGTGATGCAGTAA
ATCATAGTCTTTCCTTCATAAGTGACGGCAATGTGCTTGCTTTACATCGTCTACTCTGGAACAATCAGGAGAAAATTGGGCAGTATCTTT
CCAGCAACAGGGATCATAAAGCTGTTGGAAGACGACCTTTTGATAAGATGGCAACACTTCTTGCATACCTGGGTCCTCCAGAGCACAAAC
CTGTGGCAGATACACACTGGTCCAGCCTTAACCTTACCAGTTCAAAGTTTGAGGAATTTATGACTAGGCATCAGGTACATGAAAAAGAAG
AATTCAAGGCTTTGAAAACGTTAAGTATTTTCTACCAAGCTGGGACTTCCAAAGCTGGGAATCCTATTTTTTATTATGTTGCACGGAGGT
TCAAAACTGGTCAAATCAATGGTGATTTGCTGATATACCATGTCTTACTGACTTTAAAGCCATATTATGCAAAGCCATATGAAATTGTAG
TGGACCTTACCCATACCGGGCCTAGCAATCGCTTTAAAACAGACTTTCTCTCTAAGTGGTTTGTTGTTTTTCCTGGCTTTGCTTACGACA
ACGTCTCCGCAGTCTATATCTATAACTGTAACTCCTGGGTCAGGGAGTACACCAAGTATCATGAGCGGCTGCTGACTGGCCTCAAAGGTA
GCAAAAGGCTTGTTTTCATAGACTGTCCTGGGAAACTGGCTGAGCACATAGAGCATGAACAACAGAAACTACCTGCTGCCACCTTGGCTT
TAGAAGAGGACCTGAAGGTATTCCACAATGCTCTCAAGCTAGCTCACAAAGACACCAAAGTTTCTATTAAAGTTGGTTCTACTGCTGTCC
AAGTAACTTCAGCAGAGCGAACAAAAGTCCTAGGGCAATCAGTCTTTCTAAATGACATTTATTATGCTTCGGAAATTGAAGAAATCTGCC
TAGTAGATGAGAACCAGTTCACCTTAACCATTGCAAACCAGGGCACGCCGCTCACCTTCATGCACCAGGAGTGTGAAGCCATTGTCCAGT
CTATCATTCATATCCGGACCCGCTGGGAACTGTCACAGCCCGACTCTATCCCCCAACACACCAAGATTCGGCCAAAAGATGTCCCTGGGA
CACTGCTCAATATCGCATTACTTAATTTAGGCAGTTCTGACCCGAGTTTACGGTCAGCTGCCTATAATCTTCTGTGTGCCTTAACTTGTA
CCTTTAATTTAAAAATCGAGGGCCAGTTACTAGAGACATCAGGTTTATGTATCCCTGCCAACAACACCCTCTTTATTGTCTCTATTAGTA
AGACACTGGCAGCCAATGAGCCACACCTCACGTTAGAATTTTTGGAAGAGTGTATTTCTGGATTTAGCAAATCTAGTATTGAATTGAAAC
ACCTTTGTTTGGAATACATGACTCCATGGCTGTCAAATCTAGTTCGTTTTTGCAAGCATAATGATGATGCCAAACGACAAAGAGTTACTG
CTATTCTTGACAAGCTGATAACAATGACCATCAATGAAAAACAGATGTACCCATCTATTCAAGCAAAAATATGGGGAAGCCTTGGGCAGA
TTACAGATCTGCTTGATGTTGTACTAGACAGTTTCATCAAAACCAGTGCAACAGGTGGCTTGGGATCAATAAAAGCTGAGGTGATGGCAG
ATACTGCTGTAGCTTTGGCTTCTGGAAATGTGAAATTGGTTTCAAGCAAGGTTATTGGAAGGATGTGCAAAATAATTGACAAGACATGCT
TATCTCCAACTCCTACTTTAGAACAACATCTTATGTGGGATGATATTGCTATTTTAGCACGCTACATGCTGATGCTGTCCTTCAACAATT
CCCTTGATGTGGCAGCTCATCTTCCCTACCTCTTCCACGTTGTTACTTTCTTAGTAGCCACAGGTCCGCTCTCCCTTAGAGCTTCCACAC
ATGGACTGGTCATTAATATCATTCACTCTCTGTGTACTTGTTCACAGCTTCATTTTAGTGAAGAGACCAAGCAAGTTTTGAGACTCAGTC
TGACAGAGTTCTCATTACCCAAATTTTACTTGCTGTTTGGCATTAGCAAAGTCAAGTCAGCTGCTGTCATTGCCTTCCGTTCCAGTTACC
GGGACAGGTCATTCTCTCCTGGCTCCTATGAGAGAGAGACTTTTGCTTTGACATCCTTGGAAACAGTCACAGAAGCTTTGTTGGAGATCA
TGGAGGCATGCATGAGAGATATTCCAACGTGCAAGTGGCTGGACCAGTGGACAGAACTAGCTCAAAGATTTGCATTCCAATATAATCCAT
CCCTGCAACCAAGAGCTCTTGTTGTCTTTGGGTGTATTAGCAAACGAGTGTCTCATGGGCAGATAAAGCAGATAATCCGTATTCTTAGCA
AGGCACTTGAGAGTTGCTTAAAAGGACCTGACACTTACAACAGTCAAGTTCTGATAGAAGCTACAGTAATAGCACTAACCAAATTACAGC
CACTTCTTAATAAGGACTCGCCTCTGCACAAAGCCCTCTTTTGGGTAGCTGTGGCTGTGCTGCAGCTTGATGAGGTCAACTTGTATTCAG
CAGGTACCGCACTTCTTGAACAAAACCTGCATACTTTAGATAGTCTCCGTATATTCAATGACAAGAGTCCAGAGGAAGTATTTATGGCAA
TCCGGAATCCTCTGGAGTGGCACTGCAAGCAAATGGATCATTTTGTTGGACTCAATTTCAACTCTAACTTTAACTTTGCATTGGTTGGAC
ACCTTTTAAAAGGGTACAGGCATCCTTCACCTGCTATTGTTGCAAGAACAGTCAGAATTTTACATACACTACTAACTCTGGTTAACAAAC
ACAGAAATTGTGACAAATTTGAAGTGAATACACAGAGCGTGGCCTACTTAGCAGCAAATTATCAGAACTGTACTCAGTCTCAAGAGAAGC
TGAATGAAGATATGACTCTGTTGACCCTGTATTATGTTGGAATAGGTGTTGCTGCCTTGATTTTTGGTTACATACAGATTTCCTTGTGGA
TTATAACTGCAGCACGACAGACCAAGAGGATTCGAAAACAGTTTTTTCATTCAGTTTTGGCACAGGACATCGGCTGGTTTGATAGCTGTG
ACATCGGTGAACTTAACACTCGCATGACAGATGACATTGACAAAATCAGTGATGGTATTGGAGATAAGATTGCTCTGTTGTTTCAAAACA
TGTCTACTTTTTCGATTGGCCTGGCAGTTGGTTTGGTGAAGGGCTGGAAACTCACCCTAGTGACTCTATCCACGTCTCCTCTTATAATGG
CTTCAGCGGCAGCATGTTCTAGGATGGTCATCTCATTGACCAGTAAGGAATTAAGTGCCTATTCCAAAGCTGGGGCTGTGGCAGAAGAAG
TCTTGTCATCAATCCGAACAGTCATAGCCTTTAGGGCCCAGGAGAAAGAACTTCAAAGGTATACACAGAATCTCAAAGATGCAAAGGATT
TTGGCATAAAAAGGACTATAGCTTCAAAAGTGTCTCTTGGTGCTGTGTACTTCTTTATGAATGGAACCTATGGACTTGCTTTTTGGTATG
GAACCTCCTTGATTCTTAATGGAGAACCTGGATATACCATCGGGACTGTTCTTGCTGTTTTCTTTAGTGTAATCCATAGCAGTTATTGCA
TTGGAGCAGCAGTCCCTCACTTTGAAACCTTCGCAATAGCCCGAGGAGCTGCCTTTCATATTTTCCAGGTTATTGATAAGAAACCCAGTA
TAGATAACTTTTCCACAGCTGGATATAAACCTGAATCCATAGAAGGAACTGTGGAATTTAAAAATGTTTCTTTCAATTATCCATCAAGAC
CATCTATCAAGATTCTGAAAGGTCTGAATCTCAGAATTAAGTCTGGAGAGACAGTCGCCTTGGTCGGTCTCAATGGCAGTGGGAAGAGTA
CGGTAGTCCAGCTTCTGCAGAGGTTATATGATCCGGATGATGGCTTTATCATGGTGGATGAGAATGACATCAGAGCTTTAAATGTGCGGC
ATTATCGAGACCATATTGGAGTGGTTAGTCAAGAGCCTGTTTTGTTCGGGACCACCATCAGTAACAATATCAAGTATGGACGAGATGATG
TGACTGATGAAGAGATGGAGAGAGCAGCAAGGGAAGCAAATGCGTATGATTTTATCATGGAGTTTCCTAATAAATTTAATACATTGGTAG
GGGAAAAAGGAGCTCAAATGAGTGGAGGGCAGAAACAGAGGATCGCAATTGCTCGTGCCTTAGTTCGAAACCCCAAGATTCTGATTTTAG
ATGAGGCTACGTCTGCCCTGGATTCAGAAAGCAAGTCAGCTGTTCAAGCTGCACTGGAGAAGGCGAGCAAAGGTCGGACTACAATCGTGG
TAGCACACCGACTTTCTACTATTCGAAGTGCAGATTTGATTGTGACCCTAAAGGATGGAATGCTGGCGGAGAAAGGAGCACATGCTGAAC
TAATGGCAAAACGAGGTCTATATTATTCACTTGTGATGTCACAGGATATTAAAAAAGCTGATGAACAGATGGAGTCAATGACATATTCTA
CTGAAAGAAAGACCAACTCACTTCCTCTGCACTCTGTGAAGAGCATCAAGTCAGACTTCATTGACAAGGCTGAGGAATCCACCCAATCTA
AAGAGATAAGTCTTCCTGAAGTCTCTCTATTAAAAATTTTAAAGTTAAACAAGCCTGAATGGCCTTTTGTGGTTCTGGGGACATTGGCTT
CTGTTCTAAATGGAACTGTTCATCCAGTATTTTCCATCATCTTTGCAAAAATTATAACCATGTTTGGAAATAATGATAAAACCACATTAA
AGCATGATGCAGAAATTTATTCCATGATATTCGTCATTTTGGGTGTTATTTGCTTTGTCAGTTATTTCATGCAGGGATTATTTTACGGCA
GAGCAGGGGAAATTTTAACGATGAGATTAAGACACTTGGCCTTCAAAGCCATGTTATATCAGGATATTGCCTGGTTTGATGAAAAGGAAA
ACAGCACAGGAGGCTTGACAACAATATTAGCCATAGATATAGCACAAATTCAAGGAGCAACAGGTTCCAGGATTGGCGTCTTAACACAAA
ATGCAACTAACATGGGACTTTCAGTTATCATTTCCTTTATATATGGATGGGAGATGACATTCCTGATTCTGAGTATTGCTCCAGTACTTG
CCGTGACAGGAATGATTGAAACCGCAGCAATGACTGGATTTGCCAACAAAGATAAGCAAGAACTTAAGCATGCTGGAAAGATAGCAACTG
AAGCTTTGGAGAATATACGTACTATAGTGTCATTAACAAGGGAAAAAGCCTTCGAGCAAATGTATGAAGAGATGCTTCAGACTCAACACA
GAAATACCTCGAAGAAAGCACAGATTATTGGAAGCTGTTATGCATTCAGCCATGCCTTTATATATTTTGCCTATGCGGCAGGGTTTCGAT
TTGGAGCCTATTTAATTCAAGCTGGACGAATGACCCCAGAGGGCATGTTCATAGTTTTTACTGCAATTGCATATGGAGCTATGGCCATCG
GAGAAACGCTCGTTTTGGCTCCTGAATATTCCAAAGCCAAATCGGGGGCTGCGCATCTGTTTGCCTTGTTGGAAAAGAAACCAAATATAG
ACAGCCGCAGTCAAGAAGGGAAAAAGCCAGACACATGTGAAGGGAATTTAGAGTTTCGAGAAGTCTCTTTCTTCTATCCATGTCGCCCAG
ATGTTTTCATCCTCCGTGGCTTATCCCTCAGTATTGAGCGAGGAAAGACAGTAGCATTTGTGGGGAGCAGCGGCTGTGGGAAAAGCACTT
CTGTTCAACTTCTGCAGAGACTTTATGACCCCGTGCAAGGACAAGTGCTGTTTGATGGTGTGGATGCAAAAGAATTGAATGTACAGTGGC
TCCGTTCCCAAATAGCAATCGTTCCTCAAGAGCCTGTGCTCTTCAACTGCAGCATTGCTGAGAACATCGCCTATGGTGACAACAGCCGTG
TGGTGCCATTAGATGAGATCAAAGAAGCCGCAAATGCAGCAAATATCCATTCTTTTATTGAAGGTCTCCCTGAGAAATACAACACACAAG
TTGGACTGAAAGGAGCACAGCTTTCTGGCGGCCAGAAACAAAGACTAGCTATTGCAAGGGCTCTTCTCCAAAAACCCAAAATTTTATTGT
TGGATGAGGCCACTTCAGCCCTCGATAATGACAGTGAGAAGGTGGTTCAGCATGCCCTTGATAAAGCCAGGACGGGAAGGACATGCCTAG
TGGTCACTCACAGGCTCTCTGCAATTCAGAACGCAGATTTGATAGTGGTTCTGCACAATGGAAAGATAAAGGAACAAGGAACTCATCAAG
AGCTCCTGAGAAATCGAGACATATATTTTAAGTTAGTGAATGCACAGTCAGTGCAGTGATGCTGTTGAGGTAGCACATATTTTGATGTTC
GTGTAATGCAAAGAAGGAGTACTTAATAATTACTTGGCAAGCTTTGATCTCTTTTATTGCATATATCAATACCTAGAATCATGCTACTCA
AGTACATACATGTTCTATTCACACACCATCTGACCTTCAGATTTTTAAAAGGAAGCAAAAATTTGCTTATTTCATGTAAGTGAAATAATG
CTTATATCCTTCACTTTATAAAACTATTCTAGCACATTTGCTTGTAAAGCAGTTTTCTACAAGGTGAATTTATTTCCCATCAACTTCTGC
TATAAAATCGGAAATATGTTTCCAGGGGGAATATTATCCAATTAACCATGTTGAAGGTTTTAGCAAAGGCAGTGTAAGATAGAGTGGGGC
CTGTAGCATTGCAGGGAGAGTGTCTTTCACTTGGAATTTTGTTTTGCAGCACATATTACAGTAGTTTTGCTAGTCCCTTTTCTCCAGACC
GTAGGGATTTCTCTCAATAAGTATTCACTATTTCTCTAAATTTTATTCTATTTTTTTGTTGAGCAGGGAATAGAAAGGATTACGATGTAA
AATTTCTGGGAGGATTAGGTAGCTATCTCCTACTTCACCAGTAAGTGAAGTGCCTCACATGAGCCATCCCAAAGATTCATTATTCCAAAC
CTTGGGTTTGGCAGTATAAGTCACAGGCCTACCTGTTTATGAAAACTTACTTACTTAAAATAAGAGCTACTTTTGGGCCGGGTGCGGTGG
CTCACGCCTGTAATCCCAGAACTTTGGGAGGCCGAGGAGGGCGGATCACTTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACATGGTGA
AACCCCGTCTCTACTAAAAACACAAAAATTAGCCAATCTTGGTGGCGGGCACCTGGAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGAA
TCATTTGAACCTAGGAGGCAGAGGTTGCAGTGAGCCGAGATCTCACCACTGCACTCCAGCCTGCGCAACAGAGCGAGACTCCATCTCAAA
AAATAATAAATAAGAGCTAATTTTATTGTGGGTGAAAATTTTTAAACGTCTTTCTCTATAATAAAATAATTTCCTTAAATTTTATATATA
CTTTATCATATATAATGTGTGAATGATTTTAAAGTTCTGTGTAAATAACAATATTGGTAAAATGAGTTACATTTTCAACTTACTTAAATA
TGTAATGTCACCTGGTGATTTTATCTTTATTCTTCAGTGTATTTTCTTCCATTTACACATTTAGCTAGCCTCCCTAAAGTGTACTCTACC
AATAATTGAAATCTTGTTAAACAAAATTAAAACCATTTATATATTATGCTGCTTTCTTTAAAATGCAAAATAAAAATAAGATTGGGGACT

>In-frame_ENST00000358273_ENST00000404938_TCGA-B6-A0I9-01A_NF1_chr17_29676269_-_ABCB5_chr7_20671682_length(amino acids)=3654AA_start in transcript=254_stop in transcript=11218
MGACTPQTLSLPLPSPQPPLPALFPAQGAGPPFPPPPPGRGEDMAAHRPVEWVQAVVSRFDEQLPIKTGQQNTHTKVSTEHNKECLINIS
KYKFSLVISGLTTILKNVNNMRIFGEAAEKNLYLSQLIILDTLEKCLAGQPKDTMRLDETMLVKQLLPEICHFLHTCREGNQHAAELRNS
ASGVLFSLSCNNFNAVFSRISTRLQELTVCSEDNVDVHDIELLQYINVDCAKLKRLLKETAFKFKALKKVAQLAVINSLEKAFWNWVENY
PDEFTKLYQIPQTDMAECAEKLFDLVDGFAESTKRKAAVWPLQIILLILCPEIIQDISKDVVDENNMNKKLFLDSLRKALAGHGGSRQLT
ESAAIACVKLCKASTYINWEDNSVIFLLVQSMVVDLKNLLFNPSKPFSRGSQPADVDLMIDCLVSCFRISPHNNQHFKICLAQNSPSTFH
YVLVNSLHRIITNSALDWWPKIDAVYCHSVELRNMFGETLHKAVQGCGAHPAIRMAPSLTFKEKVTSLKFKEKPTDLETRSYKYLLLSMV
KLIHADPKLLLCNPRKQGPETQGSTAELITGLVQLVPQSHMPEIAQEAMEALLVLHQLDSIDLWNPDAPVETFWEISSQMLFYICKKLTS
HQMLSSTEILKWLREILICRNKFLLKNKQADRSSCHFLLFYGVGCDIPSSGNTSQMSMDHEELLRTPGASLRKGKGNSSMDSAAGCSGTP
PICRQAQTKLEVALYMFLWNPDTEAVLVAMSCFRHLCEEADIRCGVDEVSVHNLLPNYNTFMEFASVSNMMSTGRAALQKRVMALLRRIE
HPTAGNTEAWEDTHAKWEQATKLILNYPKAKMEDGQAAESLHKTIVKRRMSHVSGGGSIDLSDTDSLQEWINMTGFLCALGGVCLQQRSN
SGLATYSPPMGPVSERKGSMISVMSSEGNADTPVSKFMDRLLSLMVCNHEKVGLQIRTNVKDLVGLELSPALYPMLFNKLKNTISKFFDS
QGQVLLTDTNTQFVEQTIAIMKNLLDNHTEGSSEHLGQASIETMMLNLVRYVRVLGNMVHAIQIKTKLCQLVEVMMARRDDLSFCQEMKF
RNKMVEYLTDWVMGTSNQAADDDVKCLTRDLDQASMEAVVSLLAGLPLQPEEGDGVELMEAKSQLFLKYFTLFMNLLNDCSEVEDESAQT
GGRKRGMSRRLASLRHCTVLAMSNLLNANVDSGLMHSIGLGYHKDLQTRATFMEVLTKILQQGTEFDTLAETVLADRFERLVELVTMMGD
QGELPIAMALANVVPCSQWDELARVLVTLFDSRHLLYQLLWNMFSKEVELADSMQTLFRGNSLASKIMTFCFKVYGATYLQKLLDPLLRI
VITSSDWQHVSFEVDPTRLEPSESLEENQRNLLQMTEKFFHAIISSSSEFPPQLRSVCHCLYQATCHSLLNKATVKEKKENKKSVVSQRF
PQNSIGAVGSAMFLRFINPAIVSPYEAGILDKKPPPRIERGLKLMSKILQSIANHVLFTKEEHMRPFNDFVKSNFDAARRFFLDIASDCP
TSDAVNHSLSFISDGNVLALHRLLWNNQEKIGQYLSSNRDHKAVGRRPFDKMATLLAYLGPPEHKPVADTHWSSLNLTSSKFEEFMTRHQ
VHEKEEFKALKTLSIFYQAGTSKAGNPIFYYVARRFKTGQINGDLLIYHVLLTLKPYYAKPYEIVVDLTHTGPSNRFKTDFLSKWFVVFP
GFAYDNVSAVYIYNCNSWVREYTKYHERLLTGLKGSKRLVFIDCPGKLAEHIEHEQQKLPAATLALEEDLKVFHNALKLAHKDTKVSIKV
GSTAVQVTSAERTKVLGQSVFLNDIYYASEIEEICLVDENQFTLTIANQGTPLTFMHQECEAIVQSIIHIRTRWELSQPDSIPQHTKIRP
KDVPGTLLNIALLNLGSSDPSLRSAAYNLLCALTCTFNLKIEGQLLETSGLCIPANNTLFIVSISKTLAANEPHLTLEFLEECISGFSKS
SIELKHLCLEYMTPWLSNLVRFCKHNDDAKRQRVTAILDKLITMTINEKQMYPSIQAKIWGSLGQITDLLDVVLDSFIKTSATGGLGSIK
AEVMADTAVALASGNVKLVSSKVIGRMCKIIDKTCLSPTPTLEQHLMWDDIAILARYMLMLSFNNSLDVAAHLPYLFHVVTFLVATGPLS
LRASTHGLVINIIHSLCTCSQLHFSEETKQVLRLSLTEFSLPKFYLLFGISKVKSAAVIAFRSSYRDRSFSPGSYERETFALTSLETVTE
ALLEIMEACMRDIPTCKWLDQWTELAQRFAFQYNPSLQPRALVVFGCISKRVSHGQIKQIIRILSKALESCLKGPDTYNSQVLIEATVIA
LTKLQPLLNKDSPLHKALFWVAVAVLQLDEVNLYSAGTALLEQNLHTLDSLRIFNDKSPEEVFMAIRNPLEWHCKQMDHFVGLNFNSNFN
FALVGHLLKGYRHPSPAIVARTVRILHTLLTLVNKHRNCDKFEVNTQSVAYLAANYQNCTQSQEKLNEDMTLLTLYYVGIGVAALIFGYI
QISLWIITAARQTKRIRKQFFHSVLAQDIGWFDSCDIGELNTRMTDDIDKISDGIGDKIALLFQNMSTFSIGLAVGLVKGWKLTLVTLST
SPLIMASAAACSRMVISLTSKELSAYSKAGAVAEEVLSSIRTVIAFRAQEKELQRYTQNLKDAKDFGIKRTIASKVSLGAVYFFMNGTYG
LAFWYGTSLILNGEPGYTIGTVLAVFFSVIHSSYCIGAAVPHFETFAIARGAAFHIFQVIDKKPSIDNFSTAGYKPESIEGTVEFKNVSF
NYPSRPSIKILKGLNLRIKSGETVALVGLNGSGKSTVVQLLQRLYDPDDGFIMVDENDIRALNVRHYRDHIGVVSQEPVLFGTTISNNIK
YGRDDVTDEEMERAAREANAYDFIMEFPNKFNTLVGEKGAQMSGGQKQRIAIARALVRNPKILILDEATSALDSESKSAVQAALEKASKG
RTTIVVAHRLSTIRSADLIVTLKDGMLAEKGAHAELMAKRGLYYSLVMSQDIKKADEQMESMTYSTERKTNSLPLHSVKSIKSDFIDKAE
ESTQSKEISLPEVSLLKILKLNKPEWPFVVLGTLASVLNGTVHPVFSIIFAKIITMFGNNDKTTLKHDAEIYSMIFVILGVICFVSYFMQ
GLFYGRAGEILTMRLRHLAFKAMLYQDIAWFDEKENSTGGLTTILAIDIAQIQGATGSRIGVLTQNATNMGLSVIISFIYGWEMTFLILS
IAPVLAVTGMIETAAMTGFANKDKQELKHAGKIATEALENIRTIVSLTREKAFEQMYEEMLQTQHRNTSKKAQIIGSCYAFSHAFIYFAY
AAGFRFGAYLIQAGRMTPEGMFIVFTAIAYGAMAIGETLVLAPEYSKAKSGAAHLFALLEKKPNIDSRSQEGKKPDTCEGNLEFREVSFF
YPCRPDVFILRGLSLSIERGKTVAFVGSSGCGKSTSVQLLQRLYDPVQGQVLFDGVDAKELNVQWLRSQIAIVPQEPVLFNCSIAENIAY
GDNSRVVPLDEIKEAANAANIHSFIEGLPEKYNTQVGLKGAQLSGGQKQRLAIARALLQKPKILLLDEATSALDNDSEKVVQHALDKART

--------------------------------------------------------------
>In-frame_ENST00000417592_ENST00000404938_TCGA-B6-A0I9-01A_NF1_chr17_29676269_-_ABCB5_chr7_20671682_length(transcript)=5364nt_BP=464nt
AGGCATGCATGAGAGATATTCCAACGTGCAAGTGGCTGGACCAGTGGACAGAACTAGCTCAAAGGACTCGCCTCTGCACAAAGCCCTCTT
TTGGGTAGCTGTGGCTGTGCTGCAGCTTGATGAGGTCAACTTGTATTCAGCAGGTACCGCACTTCTTGAACAAAACCTGCATACTTTAGA
TAGTCTCCGTATATTCAATGACAAGAGTCCAGAGGAAGTATTTATGGCAATCCGGAATCCTCTGGAGTGGCACTGCAAGCAAATGGATCA
TTTTGTTGGACTCAATTTCAACTCTAACTTTAACTTTGCATTGGTTGGACACCTTTTAAAAGGGTACAGGCATCCTTCACCTGCTATTGT
TGCAAGAACAGTCAGAATTTTACATACACTACTAACTCTGGTTAACAAACACAGAAATTGTGACAAATTTGAAGTGAATACACAGAGCGT
GGCCTACTTAGCAGCAAATTATCAGAACTGTACTCAGTCTCAAGAGAAGCTGAATGAAGATATGACTCTGTTGACCCTGTATTATGTTGG
AATAGGTGTTGCTGCCTTGATTTTTGGTTACATACAGATTTCCTTGTGGATTATAACTGCAGCACGACAGACCAAGAGGATTCGAAAACA
GTTTTTTCATTCAGTTTTGGCACAGGACATCGGCTGGTTTGATAGCTGTGACATCGGTGAACTTAACACTCGCATGACAGATGACATTGA
CAAAATCAGTGATGGTATTGGAGATAAGATTGCTCTGTTGTTTCAAAACATGTCTACTTTTTCGATTGGCCTGGCAGTTGGTTTGGTGAA
GGGCTGGAAACTCACCCTAGTGACTCTATCCACGTCTCCTCTTATAATGGCTTCAGCGGCAGCATGTTCTAGGATGGTCATCTCATTGAC
CAGTAAGGAATTAAGTGCCTATTCCAAAGCTGGGGCTGTGGCAGAAGAAGTCTTGTCATCAATCCGAACAGTCATAGCCTTTAGGGCCCA
GGAGAAAGAACTTCAAAGGTATACACAGAATCTCAAAGATGCAAAGGATTTTGGCATAAAAAGGACTATAGCTTCAAAAGTGTCTCTTGG
TGCTGTGTACTTCTTTATGAATGGAACCTATGGACTTGCTTTTTGGTATGGAACCTCCTTGATTCTTAATGGAGAACCTGGATATACCAT
CGGGACTGTTCTTGCTGTTTTCTTTAGTGTAATCCATAGCAGTTATTGCATTGGAGCAGCAGTCCCTCACTTTGAAACCTTCGCAATAGC
CCGAGGAGCTGCCTTTCATATTTTCCAGGTTATTGATAAGAAACCCAGTATAGATAACTTTTCCACAGCTGGATATAAACCTGAATCCAT
AGAAGGAACTGTGGAATTTAAAAATGTTTCTTTCAATTATCCATCAAGACCATCTATCAAGATTCTGAAAGGTCTGAATCTCAGAATTAA
GTCTGGAGAGACAGTCGCCTTGGTCGGTCTCAATGGCAGTGGGAAGAGTACGGTAGTCCAGCTTCTGCAGAGGTTATATGATCCGGATGA
TGGCTTTATCATGGTGGATGAGAATGACATCAGAGCTTTAAATGTGCGGCATTATCGAGACCATATTGGAGTGGTTAGTCAAGAGCCTGT
TTTGTTCGGGACCACCATCAGTAACAATATCAAGTATGGACGAGATGATGTGACTGATGAAGAGATGGAGAGAGCAGCAAGGGAAGCAAA
TGCGTATGATTTTATCATGGAGTTTCCTAATAAATTTAATACATTGGTAGGGGAAAAAGGAGCTCAAATGAGTGGAGGGCAGAAACAGAG
GATCGCAATTGCTCGTGCCTTAGTTCGAAACCCCAAGATTCTGATTTTAGATGAGGCTACGTCTGCCCTGGATTCAGAAAGCAAGTCAGC
TGTTCAAGCTGCACTGGAGAAGGCGAGCAAAGGTCGGACTACAATCGTGGTAGCACACCGACTTTCTACTATTCGAAGTGCAGATTTGAT
TGTGACCCTAAAGGATGGAATGCTGGCGGAGAAAGGAGCACATGCTGAACTAATGGCAAAACGAGGTCTATATTATTCACTTGTGATGTC
ACAGGATATTAAAAAAGCTGATGAACAGATGGAGTCAATGACATATTCTACTGAAAGAAAGACCAACTCACTTCCTCTGCACTCTGTGAA
GAGCATCAAGTCAGACTTCATTGACAAGGCTGAGGAATCCACCCAATCTAAAGAGATAAGTCTTCCTGAAGTCTCTCTATTAAAAATTTT
AAAGTTAAACAAGCCTGAATGGCCTTTTGTGGTTCTGGGGACATTGGCTTCTGTTCTAAATGGAACTGTTCATCCAGTATTTTCCATCAT
CTTTGCAAAAATTATAACCATGTTTGGAAATAATGATAAAACCACATTAAAGCATGATGCAGAAATTTATTCCATGATATTCGTCATTTT
GGGTGTTATTTGCTTTGTCAGTTATTTCATGCAGGGATTATTTTACGGCAGAGCAGGGGAAATTTTAACGATGAGATTAAGACACTTGGC
CTTCAAAGCCATGTTATATCAGGATATTGCCTGGTTTGATGAAAAGGAAAACAGCACAGGAGGCTTGACAACAATATTAGCCATAGATAT
AGCACAAATTCAAGGAGCAACAGGTTCCAGGATTGGCGTCTTAACACAAAATGCAACTAACATGGGACTTTCAGTTATCATTTCCTTTAT
ATATGGATGGGAGATGACATTCCTGATTCTGAGTATTGCTCCAGTACTTGCCGTGACAGGAATGATTGAAACCGCAGCAATGACTGGATT
TGCCAACAAAGATAAGCAAGAACTTAAGCATGCTGGAAAGATAGCAACTGAAGCTTTGGAGAATATACGTACTATAGTGTCATTAACAAG
GGAAAAAGCCTTCGAGCAAATGTATGAAGAGATGCTTCAGACTCAACACAGAAATACCTCGAAGAAAGCACAGATTATTGGAAGCTGTTA
TGCATTCAGCCATGCCTTTATATATTTTGCCTATGCGGCAGGGTTTCGATTTGGAGCCTATTTAATTCAAGCTGGACGAATGACCCCAGA
GGGCATGTTCATAGTTTTTACTGCAATTGCATATGGAGCTATGGCCATCGGAGAAACGCTCGTTTTGGCTCCTGAATATTCCAAAGCCAA
ATCGGGGGCTGCGCATCTGTTTGCCTTGTTGGAAAAGAAACCAAATATAGACAGCCGCAGTCAAGAAGGGAAAAAGCCAGACACATGTGA
AGGGAATTTAGAGTTTCGAGAAGTCTCTTTCTTCTATCCATGTCGCCCAGATGTTTTCATCCTCCGTGGCTTATCCCTCAGTATTGAGCG
AGGAAAGACAGTAGCATTTGTGGGGAGCAGCGGCTGTGGGAAAAGCACTTCTGTTCAACTTCTGCAGAGACTTTATGACCCCGTGCAAGG
ACAAGTGCTGTTTGATGGTGTGGATGCAAAAGAATTGAATGTACAGTGGCTCCGTTCCCAAATAGCAATCGTTCCTCAAGAGCCTGTGCT
CTTCAACTGCAGCATTGCTGAGAACATCGCCTATGGTGACAACAGCCGTGTGGTGCCATTAGATGAGATCAAAGAAGCCGCAAATGCAGC
AAATATCCATTCTTTTATTGAAGGTCTCCCTGAGAAATACAACACACAAGTTGGACTGAAAGGAGCACAGCTTTCTGGCGGCCAGAAACA
AAGACTAGCTATTGCAAGGGCTCTTCTCCAAAAACCCAAAATTTTATTGTTGGATGAGGCCACTTCAGCCCTCGATAATGACAGTGAGAA
GGTGGTTCAGCATGCCCTTGATAAAGCCAGGACGGGAAGGACATGCCTAGTGGTCACTCACAGGCTCTCTGCAATTCAGAACGCAGATTT
GATAGTGGTTCTGCACAATGGAAAGATAAAGGAACAAGGAACTCATCAAGAGCTCCTGAGAAATCGAGACATATATTTTAAGTTAGTGAA
TGCACAGTCAGTGCAGTGATGCTGTTGAGGTAGCACATATTTTGATGTTCGTGTAATGCAAAGAAGGAGTACTTAATAATTACTTGGCAA
GCTTTGATCTCTTTTATTGCATATATCAATACCTAGAATCATGCTACTCAAGTACATACATGTTCTATTCACACACCATCTGACCTTCAG
ATTTTTAAAAGGAAGCAAAAATTTGCTTATTTCATGTAAGTGAAATAATGCTTATATCCTTCACTTTATAAAACTATTCTAGCACATTTG
CTTGTAAAGCAGTTTTCTACAAGGTGAATTTATTTCCCATCAACTTCTGCTATAAAATCGGAAATATGTTTCCAGGGGGAATATTATCCA
ATTAACCATGTTGAAGGTTTTAGCAAAGGCAGTGTAAGATAGAGTGGGGCCTGTAGCATTGCAGGGAGAGTGTCTTTCACTTGGAATTTT
GTTTTGCAGCACATATTACAGTAGTTTTGCTAGTCCCTTTTCTCCAGACCGTAGGGATTTCTCTCAATAAGTATTCACTATTTCTCTAAA
TTTTATTCTATTTTTTTGTTGAGCAGGGAATAGAAAGGATTACGATGTAAAATTTCTGGGAGGATTAGGTAGCTATCTCCTACTTCACCA
GTAAGTGAAGTGCCTCACATGAGCCATCCCAAAGATTCATTATTCCAAACCTTGGGTTTGGCAGTATAAGTCACAGGCCTACCTGTTTAT
GAAAACTTACTTACTTAAAATAAGAGCTACTTTTGGGCCGGGTGCGGTGGCTCACGCCTGTAATCCCAGAACTTTGGGAGGCCGAGGAGG
GCGGATCACTTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACATGGTGAAACCCCGTCTCTACTAAAAACACAAAAATTAGCCAATCTT
GGTGGCGGGCACCTGGAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATCATTTGAACCTAGGAGGCAGAGGTTGCAGTGAGCCGAGA
TCTCACCACTGCACTCCAGCCTGCGCAACAGAGCGAGACTCCATCTCAAAAAATAATAAATAAGAGCTAATTTTATTGTGGGTGAAAATT
TTTAAACGTCTTTCTCTATAATAAAATAATTTCCTTAAATTTTATATATACTTTATCATATATAATGTGTGAATGATTTTAAAGTTCTGT
GTAAATAACAATATTGGTAAAATGAGTTACATTTTCAACTTACTTAAATATGTAATGTCACCTGGTGATTTTATCTTTATTCTTCAGTGT
ATTTTCTTCCATTTACACATTTAGCTAGCCTCCCTAAAGTGTACTCTACCAATAATTGAAATCTTGTTAAACAAAATTAAAACCATTTAT

>In-frame_ENST00000417592_ENST00000404938_TCGA-B6-A0I9-01A_NF1_chr17_29676269_-_ABCB5_chr7_20671682_length(amino acids)=1324AA_start in transcript=4_stop in transcript=3978
MHERYSNVQVAGPVDRTSSKDSPLHKALFWVAVAVLQLDEVNLYSAGTALLEQNLHTLDSLRIFNDKSPEEVFMAIRNPLEWHCKQMDHF
VGLNFNSNFNFALVGHLLKGYRHPSPAIVARTVRILHTLLTLVNKHRNCDKFEVNTQSVAYLAANYQNCTQSQEKLNEDMTLLTLYYVGI
GVAALIFGYIQISLWIITAARQTKRIRKQFFHSVLAQDIGWFDSCDIGELNTRMTDDIDKISDGIGDKIALLFQNMSTFSIGLAVGLVKG
WKLTLVTLSTSPLIMASAAACSRMVISLTSKELSAYSKAGAVAEEVLSSIRTVIAFRAQEKELQRYTQNLKDAKDFGIKRTIASKVSLGA
VYFFMNGTYGLAFWYGTSLILNGEPGYTIGTVLAVFFSVIHSSYCIGAAVPHFETFAIARGAAFHIFQVIDKKPSIDNFSTAGYKPESIE
GTVEFKNVSFNYPSRPSIKILKGLNLRIKSGETVALVGLNGSGKSTVVQLLQRLYDPDDGFIMVDENDIRALNVRHYRDHIGVVSQEPVL
FGTTISNNIKYGRDDVTDEEMERAAREANAYDFIMEFPNKFNTLVGEKGAQMSGGQKQRIAIARALVRNPKILILDEATSALDSESKSAV
QAALEKASKGRTTIVVAHRLSTIRSADLIVTLKDGMLAEKGAHAELMAKRGLYYSLVMSQDIKKADEQMESMTYSTERKTNSLPLHSVKS
IKSDFIDKAEESTQSKEISLPEVSLLKILKLNKPEWPFVVLGTLASVLNGTVHPVFSIIFAKIITMFGNNDKTTLKHDAEIYSMIFVILG
VICFVSYFMQGLFYGRAGEILTMRLRHLAFKAMLYQDIAWFDEKENSTGGLTTILAIDIAQIQGATGSRIGVLTQNATNMGLSVIISFIY
GWEMTFLILSIAPVLAVTGMIETAAMTGFANKDKQELKHAGKIATEALENIRTIVSLTREKAFEQMYEEMLQTQHRNTSKKAQIIGSCYA
FSHAFIYFAYAAGFRFGAYLIQAGRMTPEGMFIVFTAIAYGAMAIGETLVLAPEYSKAKSGAAHLFALLEKKPNIDSRSQEGKKPDTCEG
NLEFREVSFFYPCRPDVFILRGLSLSIERGKTVAFVGSSGCGKSTSVQLLQRLYDPVQGQVLFDGVDAKELNVQWLRSQIAIVPQEPVLF
NCSIAENIAYGDNSRVVPLDEIKEAANAANIHSFIEGLPEKYNTQVGLKGAQLSGGQKQRLAIARALLQKPKILLLDEATSALDNDSEKV

--------------------------------------------------------------
>In-frame_ENST00000444181_ENST00000404938_TCGA-B6-A0I9-01A_NF1_chr17_29676269_-_ABCB5_chr7_20671682_length(transcript)=5604nt_BP=704nt
AGGCATGCATGAGAGATATTCCAACGTGCAAGTGGCTGGACCAGTGGACAGAACTAGCTCAAAGTTCTGTGGATCTTTTAATTGCAGATT
TGCATTCCAATATAATCCATCCCTGCAACCAAGAGCTCTTGTTGTCTTTGGGTGTATTAGCAAACGAGTGTCTCATGGGCAGATAAAGCA
GATAATCCGTATTCTTAGCAAGGCACTTGAGAGTTGCTTAAAAGGACCTGACACTTACAACAGTCAAGTTCTGATAGAAGCTACAGTAAT
AGCACTAACCAAATTACAGCCACTTCTTAATAAGGACTCGCCTCTGCACAAAGCCCTCTTTTGGGTAGCTGTGGCTGTGCTGCAGCTTGA
TGAGGTCAACTTGTATTCAGCAGGTACCGCACTTCTTGAACAAAACCTGCATACTTTAGATAGTCTCCGTATATTCAATGACAAGAGTCC
AGAGGAAGTATTTATGGCAATCCGGAATCCTCTGGAGTGGCACTGCAAGCAAATGGATCATTTTGTTGGACTCAATTTCAACTCTAACTT
TAACTTTGCATTGGTTGGACACCTTTTAAAAGGGTACAGGCATCCTTCACCTGCTATTGTTGCAAGAACAGTCAGAATTTTACATACACT
ACTAACTCTGGTTAACAAACACAGAAATTGTGACAAATTTGAAGTGAATACACAGAGCGTGGCCTACTTAGCAGCAAATTATCAGAACTG
TACTCAGTCTCAAGAGAAGCTGAATGAAGATATGACTCTGTTGACCCTGTATTATGTTGGAATAGGTGTTGCTGCCTTGATTTTTGGTTA
CATACAGATTTCCTTGTGGATTATAACTGCAGCACGACAGACCAAGAGGATTCGAAAACAGTTTTTTCATTCAGTTTTGGCACAGGACAT
CGGCTGGTTTGATAGCTGTGACATCGGTGAACTTAACACTCGCATGACAGATGACATTGACAAAATCAGTGATGGTATTGGAGATAAGAT
TGCTCTGTTGTTTCAAAACATGTCTACTTTTTCGATTGGCCTGGCAGTTGGTTTGGTGAAGGGCTGGAAACTCACCCTAGTGACTCTATC
CACGTCTCCTCTTATAATGGCTTCAGCGGCAGCATGTTCTAGGATGGTCATCTCATTGACCAGTAAGGAATTAAGTGCCTATTCCAAAGC
TGGGGCTGTGGCAGAAGAAGTCTTGTCATCAATCCGAACAGTCATAGCCTTTAGGGCCCAGGAGAAAGAACTTCAAAGGTATACACAGAA
TCTCAAAGATGCAAAGGATTTTGGCATAAAAAGGACTATAGCTTCAAAAGTGTCTCTTGGTGCTGTGTACTTCTTTATGAATGGAACCTA
TGGACTTGCTTTTTGGTATGGAACCTCCTTGATTCTTAATGGAGAACCTGGATATACCATCGGGACTGTTCTTGCTGTTTTCTTTAGTGT
AATCCATAGCAGTTATTGCATTGGAGCAGCAGTCCCTCACTTTGAAACCTTCGCAATAGCCCGAGGAGCTGCCTTTCATATTTTCCAGGT
TATTGATAAGAAACCCAGTATAGATAACTTTTCCACAGCTGGATATAAACCTGAATCCATAGAAGGAACTGTGGAATTTAAAAATGTTTC
TTTCAATTATCCATCAAGACCATCTATCAAGATTCTGAAAGGTCTGAATCTCAGAATTAAGTCTGGAGAGACAGTCGCCTTGGTCGGTCT
CAATGGCAGTGGGAAGAGTACGGTAGTCCAGCTTCTGCAGAGGTTATATGATCCGGATGATGGCTTTATCATGGTGGATGAGAATGACAT
CAGAGCTTTAAATGTGCGGCATTATCGAGACCATATTGGAGTGGTTAGTCAAGAGCCTGTTTTGTTCGGGACCACCATCAGTAACAATAT
CAAGTATGGACGAGATGATGTGACTGATGAAGAGATGGAGAGAGCAGCAAGGGAAGCAAATGCGTATGATTTTATCATGGAGTTTCCTAA
TAAATTTAATACATTGGTAGGGGAAAAAGGAGCTCAAATGAGTGGAGGGCAGAAACAGAGGATCGCAATTGCTCGTGCCTTAGTTCGAAA
CCCCAAGATTCTGATTTTAGATGAGGCTACGTCTGCCCTGGATTCAGAAAGCAAGTCAGCTGTTCAAGCTGCACTGGAGAAGGCGAGCAA
AGGTCGGACTACAATCGTGGTAGCACACCGACTTTCTACTATTCGAAGTGCAGATTTGATTGTGACCCTAAAGGATGGAATGCTGGCGGA
GAAAGGAGCACATGCTGAACTAATGGCAAAACGAGGTCTATATTATTCACTTGTGATGTCACAGGATATTAAAAAAGCTGATGAACAGAT
GGAGTCAATGACATATTCTACTGAAAGAAAGACCAACTCACTTCCTCTGCACTCTGTGAAGAGCATCAAGTCAGACTTCATTGACAAGGC
TGAGGAATCCACCCAATCTAAAGAGATAAGTCTTCCTGAAGTCTCTCTATTAAAAATTTTAAAGTTAAACAAGCCTGAATGGCCTTTTGT
GGTTCTGGGGACATTGGCTTCTGTTCTAAATGGAACTGTTCATCCAGTATTTTCCATCATCTTTGCAAAAATTATAACCATGTTTGGAAA
TAATGATAAAACCACATTAAAGCATGATGCAGAAATTTATTCCATGATATTCGTCATTTTGGGTGTTATTTGCTTTGTCAGTTATTTCAT
GCAGGGATTATTTTACGGCAGAGCAGGGGAAATTTTAACGATGAGATTAAGACACTTGGCCTTCAAAGCCATGTTATATCAGGATATTGC
CTGGTTTGATGAAAAGGAAAACAGCACAGGAGGCTTGACAACAATATTAGCCATAGATATAGCACAAATTCAAGGAGCAACAGGTTCCAG
GATTGGCGTCTTAACACAAAATGCAACTAACATGGGACTTTCAGTTATCATTTCCTTTATATATGGATGGGAGATGACATTCCTGATTCT
GAGTATTGCTCCAGTACTTGCCGTGACAGGAATGATTGAAACCGCAGCAATGACTGGATTTGCCAACAAAGATAAGCAAGAACTTAAGCA
TGCTGGAAAGATAGCAACTGAAGCTTTGGAGAATATACGTACTATAGTGTCATTAACAAGGGAAAAAGCCTTCGAGCAAATGTATGAAGA
GATGCTTCAGACTCAACACAGAAATACCTCGAAGAAAGCACAGATTATTGGAAGCTGTTATGCATTCAGCCATGCCTTTATATATTTTGC
CTATGCGGCAGGGTTTCGATTTGGAGCCTATTTAATTCAAGCTGGACGAATGACCCCAGAGGGCATGTTCATAGTTTTTACTGCAATTGC
ATATGGAGCTATGGCCATCGGAGAAACGCTCGTTTTGGCTCCTGAATATTCCAAAGCCAAATCGGGGGCTGCGCATCTGTTTGCCTTGTT
GGAAAAGAAACCAAATATAGACAGCCGCAGTCAAGAAGGGAAAAAGCCAGACACATGTGAAGGGAATTTAGAGTTTCGAGAAGTCTCTTT
CTTCTATCCATGTCGCCCAGATGTTTTCATCCTCCGTGGCTTATCCCTCAGTATTGAGCGAGGAAAGACAGTAGCATTTGTGGGGAGCAG
CGGCTGTGGGAAAAGCACTTCTGTTCAACTTCTGCAGAGACTTTATGACCCCGTGCAAGGACAAGTGCTGTTTGATGGTGTGGATGCAAA
AGAATTGAATGTACAGTGGCTCCGTTCCCAAATAGCAATCGTTCCTCAAGAGCCTGTGCTCTTCAACTGCAGCATTGCTGAGAACATCGC
CTATGGTGACAACAGCCGTGTGGTGCCATTAGATGAGATCAAAGAAGCCGCAAATGCAGCAAATATCCATTCTTTTATTGAAGGTCTCCC
TGAGAAATACAACACACAAGTTGGACTGAAAGGAGCACAGCTTTCTGGCGGCCAGAAACAAAGACTAGCTATTGCAAGGGCTCTTCTCCA
AAAACCCAAAATTTTATTGTTGGATGAGGCCACTTCAGCCCTCGATAATGACAGTGAGAAGGTGGTTCAGCATGCCCTTGATAAAGCCAG
GACGGGAAGGACATGCCTAGTGGTCACTCACAGGCTCTCTGCAATTCAGAACGCAGATTTGATAGTGGTTCTGCACAATGGAAAGATAAA
GGAACAAGGAACTCATCAAGAGCTCCTGAGAAATCGAGACATATATTTTAAGTTAGTGAATGCACAGTCAGTGCAGTGATGCTGTTGAGG
TAGCACATATTTTGATGTTCGTGTAATGCAAAGAAGGAGTACTTAATAATTACTTGGCAAGCTTTGATCTCTTTTATTGCATATATCAAT
ACCTAGAATCATGCTACTCAAGTACATACATGTTCTATTCACACACCATCTGACCTTCAGATTTTTAAAAGGAAGCAAAAATTTGCTTAT
TTCATGTAAGTGAAATAATGCTTATATCCTTCACTTTATAAAACTATTCTAGCACATTTGCTTGTAAAGCAGTTTTCTACAAGGTGAATT
TATTTCCCATCAACTTCTGCTATAAAATCGGAAATATGTTTCCAGGGGGAATATTATCCAATTAACCATGTTGAAGGTTTTAGCAAAGGC
AGTGTAAGATAGAGTGGGGCCTGTAGCATTGCAGGGAGAGTGTCTTTCACTTGGAATTTTGTTTTGCAGCACATATTACAGTAGTTTTGC
TAGTCCCTTTTCTCCAGACCGTAGGGATTTCTCTCAATAAGTATTCACTATTTCTCTAAATTTTATTCTATTTTTTTGTTGAGCAGGGAA
TAGAAAGGATTACGATGTAAAATTTCTGGGAGGATTAGGTAGCTATCTCCTACTTCACCAGTAAGTGAAGTGCCTCACATGAGCCATCCC
AAAGATTCATTATTCCAAACCTTGGGTTTGGCAGTATAAGTCACAGGCCTACCTGTTTATGAAAACTTACTTACTTAAAATAAGAGCTAC
TTTTGGGCCGGGTGCGGTGGCTCACGCCTGTAATCCCAGAACTTTGGGAGGCCGAGGAGGGCGGATCACTTGAGGTCAGGAGTTCGAGAC
CAGCCTGGCCAACATGGTGAAACCCCGTCTCTACTAAAAACACAAAAATTAGCCAATCTTGGTGGCGGGCACCTGGAATCCCAGCTACTT
GGGAGGCTGAGGCAGGAGAATCATTTGAACCTAGGAGGCAGAGGTTGCAGTGAGCCGAGATCTCACCACTGCACTCCAGCCTGCGCAACA
GAGCGAGACTCCATCTCAAAAAATAATAAATAAGAGCTAATTTTATTGTGGGTGAAAATTTTTAAACGTCTTTCTCTATAATAAAATAAT
TTCCTTAAATTTTATATATACTTTATCATATATAATGTGTGAATGATTTTAAAGTTCTGTGTAAATAACAATATTGGTAAAATGAGTTAC
ATTTTCAACTTACTTAAATATGTAATGTCACCTGGTGATTTTATCTTTATTCTTCAGTGTATTTTCTTCCATTTACACATTTAGCTAGCC
TCCCTAAAGTGTACTCTACCAATAATTGAAATCTTGTTAAACAAAATTAAAACCATTTATATATTATGCTGCTTTCTTTAAAATGCAAAA

>In-frame_ENST00000444181_ENST00000404938_TCGA-B6-A0I9-01A_NF1_chr17_29676269_-_ABCB5_chr7_20671682_length(amino acids)=1404AA_start in transcript=4_stop in transcript=4218
MHERYSNVQVAGPVDRTSSKFCGSFNCRFAFQYNPSLQPRALVVFGCISKRVSHGQIKQIIRILSKALESCLKGPDTYNSQVLIEATVIA
LTKLQPLLNKDSPLHKALFWVAVAVLQLDEVNLYSAGTALLEQNLHTLDSLRIFNDKSPEEVFMAIRNPLEWHCKQMDHFVGLNFNSNFN
FALVGHLLKGYRHPSPAIVARTVRILHTLLTLVNKHRNCDKFEVNTQSVAYLAANYQNCTQSQEKLNEDMTLLTLYYVGIGVAALIFGYI
QISLWIITAARQTKRIRKQFFHSVLAQDIGWFDSCDIGELNTRMTDDIDKISDGIGDKIALLFQNMSTFSIGLAVGLVKGWKLTLVTLST
SPLIMASAAACSRMVISLTSKELSAYSKAGAVAEEVLSSIRTVIAFRAQEKELQRYTQNLKDAKDFGIKRTIASKVSLGAVYFFMNGTYG
LAFWYGTSLILNGEPGYTIGTVLAVFFSVIHSSYCIGAAVPHFETFAIARGAAFHIFQVIDKKPSIDNFSTAGYKPESIEGTVEFKNVSF
NYPSRPSIKILKGLNLRIKSGETVALVGLNGSGKSTVVQLLQRLYDPDDGFIMVDENDIRALNVRHYRDHIGVVSQEPVLFGTTISNNIK
YGRDDVTDEEMERAAREANAYDFIMEFPNKFNTLVGEKGAQMSGGQKQRIAIARALVRNPKILILDEATSALDSESKSAVQAALEKASKG
RTTIVVAHRLSTIRSADLIVTLKDGMLAEKGAHAELMAKRGLYYSLVMSQDIKKADEQMESMTYSTERKTNSLPLHSVKSIKSDFIDKAE
ESTQSKEISLPEVSLLKILKLNKPEWPFVVLGTLASVLNGTVHPVFSIIFAKIITMFGNNDKTTLKHDAEIYSMIFVILGVICFVSYFMQ
GLFYGRAGEILTMRLRHLAFKAMLYQDIAWFDEKENSTGGLTTILAIDIAQIQGATGSRIGVLTQNATNMGLSVIISFIYGWEMTFLILS
IAPVLAVTGMIETAAMTGFANKDKQELKHAGKIATEALENIRTIVSLTREKAFEQMYEEMLQTQHRNTSKKAQIIGSCYAFSHAFIYFAY
AAGFRFGAYLIQAGRMTPEGMFIVFTAIAYGAMAIGETLVLAPEYSKAKSGAAHLFALLEKKPNIDSRSQEGKKPDTCEGNLEFREVSFF
YPCRPDVFILRGLSLSIERGKTVAFVGSSGCGKSTSVQLLQRLYDPVQGQVLFDGVDAKELNVQWLRSQIAIVPQEPVLFNCSIAENIAY
GDNSRVVPLDEIKEAANAANIHSFIEGLPEKYNTQVGLKGAQLSGGQKQRLAIARALLQKPKILLLDEATSALDNDSEKVVQHALDKART

--------------------------------------------------------------

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Fusion Gene PPI Analysis for NF1-ABCB5


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for NF1-ABCB5


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for NF1-ABCB5


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneNF1C0027831Neurofibromatosis 144CTD_human;GENOMICS_ENGLAND;UNIPROT
HgeneNF1C1708353Hereditary Paraganglioma-Pheochromocytoma Syndrome10CLINGEN
HgeneNF1C0349639Juvenile Myelomonocytic Leukemia7CTD_human;GENOMICS_ENGLAND;ORPHANET
HgeneNF1C2931482Neurofibromatosis-Noonan syndrome6CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
HgeneNF1C0553586Cafe-au-lait macules with pulmonary stenosis5CTD_human;GENOMICS_ENGLAND;ORPHANET
HgeneNF1C0162678Neurofibromatoses3CGI;CTD_human;GENOMICS_ENGLAND
HgeneNF1C0004114Astrocytoma2CTD_human
HgeneNF1C0023467Leukemia, Myelocytic, Acute2CTD_human
HgeneNF1C0025202melanoma2CGI;CTD_human
HgeneNF1C0026998Acute Myeloid Leukemia, M12CTD_human
HgeneNF1C0205768Subependymal Giant Cell Astrocytoma2CTD_human
HgeneNF1C0206727Nerve Sheath Tumors2CTD_human
HgeneNF1C0280783Juvenile Pilocytic Astrocytoma2CTD_human
HgeneNF1C0280785Diffuse Astrocytoma2CTD_human
HgeneNF1C0334579Anaplastic astrocytoma2CTD_human
HgeneNF1C0334580Protoplasmic astrocytoma2CTD_human
HgeneNF1C0334581Gemistocytic astrocytoma2CTD_human
HgeneNF1C0334582Fibrillary Astrocytoma2CTD_human
HgeneNF1C0334583Pilocytic Astrocytoma2CTD_human
HgeneNF1C0338070Childhood Cerebral Astrocytoma2CTD_human
HgeneNF1C0547065Mixed oligoastrocytoma2CTD_human
HgeneNF1C0750935Cerebral Astrocytoma2CTD_human
HgeneNF1C0750936Intracranial Astrocytoma2CTD_human
HgeneNF1C0751689Peripheral Nerve Sheath Neoplasm2CTD_human
HgeneNF1C0751691Perineurioma2CTD_human
HgeneNF1C1704230Grade I Astrocytoma2CTD_human
HgeneNF1C1834235NEUROFIBROMATOSIS, FAMILIAL SPINAL2CTD_human;GENOMICS_ENGLAND;UNIPROT
HgeneNF1C1879321Acute Myeloid Leukemia (AML-M2)2CTD_human
HgeneNF1C0001430Adenoma1CTD_human
HgeneNF1C0004352Autistic Disorder1CTD_human
HgeneNF1C0016057Fibrosarcoma1CTD_human
HgeneNF1C0017636Glioblastoma1CTD_human
HgeneNF1C0017638Glioma1CGI;CTD_human
HgeneNF1C0020796Profound Mental Retardation1CTD_human
HgeneNF1C0023186Learning Disorders1CTD_human
HgeneNF1C0023827liposarcoma1CTD_human
HgeneNF1C0025363Mental Retardation, Psychosocial1CTD_human
HgeneNF1C0026654Moyamoya Disease1GENOMICS_ENGLAND
HgeneNF1C0027809Neurilemmoma1CTD_human
HgeneNF1C0027830neurofibroma1CTD_human
HgeneNF1C0027962Melanocytic nevus1CTD_human
HgeneNF1C0028326Noonan Syndrome1GENOMICS_ENGLAND
HgeneNF1C0031511Pheochromocytoma1CTD_human
HgeneNF1C0035320Retinal Neovascularization1CTD_human
HgeneNF1C0205646Adenoma, Basal Cell1CTD_human
HgeneNF1C0205647Follicular adenoma1CTD_human
HgeneNF1C0205648Adenoma, Microcystic1CTD_human
HgeneNF1C0205649Adenoma, Monomorphic1CTD_human
HgeneNF1C0205650Papillary adenoma1CTD_human
HgeneNF1C0205651Adenoma, Trabecular1CTD_human
HgeneNF1C0205824Liposarcoma, Dedifferentiated1CTD_human
HgeneNF1C0205825Liposarcoma, Pleomorphic1CTD_human
HgeneNF1C0205944Sarcoma, Epithelioid1CTD_human
HgeneNF1C0205945Sarcoma, Spindle Cell1CTD_human
HgeneNF1C0259783mixed gliomas1CTD_human
HgeneNF1C0334588Giant Cell Glioblastoma1CTD_human
HgeneNF1C0555198Malignant Glioma1CTD_human
HgeneNF1C0751262Adult Learning Disorders1CTD_human
HgeneNF1C0751263Learning Disturbance1CTD_human
HgeneNF1C0751265Learning Disabilities1CTD_human
HgeneNF1C0751374Schwannomatosis, Plexiform1CTD_human
HgeneNF1C0917816Mental deficiency1CTD_human
HgeneNF1C0917817Neurofibromatosis 31CTD_human
HgeneNF1C1257877Pheochromocytoma, Extra-Adrenal1CTD_human
HgeneNF1C1261473Sarcoma1CTD_human
HgeneNF1C1330966Developmental Academic Disorder1CTD_human
HgeneNF1C1370889Liposarcoma, well differentiated1CTD_human
HgeneNF1C1621958Glioblastoma Multiforme1CTD_human
HgeneNF1C3150928NF1 Microdeletion Syndrome1ORPHANET
HgeneNF1C3714756Intellectual Disability1CTD_human
TgeneABCB5C0009402Colorectal Carcinoma1CTD_human;UNIPROT
TgeneABCB5C0009404Colorectal Neoplasms1CTD_human
TgeneABCB5C0025202melanoma1CTD_human