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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:NFE2L1-PNPO (FusionGDB2 ID:58476)

Fusion Gene Summary for NFE2L1-PNPO

check button Fusion gene summary
Fusion gene informationFusion gene name: NFE2L1-PNPO
Fusion gene ID: 58476
HgeneTgene
Gene symbol

NFE2L1

PNPO

Gene ID

4779

55163

Gene namenuclear factor, erythroid 2 like 1pyridoxamine 5'-phosphate oxidase
SynonymsLCR-F1|NRF1|TCF11HEL-S-302|PDXPO
Cytomap

17q21.32

17q21.32

Type of geneprotein-codingprotein-coding
Descriptionendoplasmic reticulum membrane sensor NFE2L1NF-E2-related factor 1NFE2-related factor 1TCF-11locus control region-factor 1nuclear factor erythroid 2-related factor 1nuclear factor, erythroid derived 2, like 1protein NRF1, p120 formtranscription fapyridoxine-5'-phosphate oxidaseepididymis secretory protein Li 302epididymis secretory sperm binding proteinpyridoxal 5'-phosphate synthasepyridoxamine-phosphate oxidasepyridoxine 5'-phosphate oxidase
Modification date2020031320200313
UniProtAcc

Q14494

.
Ensembl transtripts involved in fusion geneENST00000362042, ENST00000585291, 
ENST00000357480, ENST00000361665, 
ENST00000579481, ENST00000582155, 
ENST00000583378, ENST00000536222, 
ENST00000544840, ENST00000434554, 
ENST00000225573, ENST00000534893, 
Fusion gene scores* DoF score18 X 12 X 13=28083 X 3 X 2=18
# samples 203
** MAII scorelog2(20/2808*10)=-3.81147103052984
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(3/18*10)=0.736965594166206
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: NFE2L1 [Title/Abstract] AND PNPO [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointNFE2L1(46134864)-PNPO(46020672), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgenePNPO

GO:0042823

pyridoxal phosphate biosynthetic process

12824491


check buttonFusion gene breakpoints across NFE2L1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across PNPO (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4UCECTCGA-EY-A2OQ-01ANFE2L1chr17

46134864

+PNPOchr17

46020672

+


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Fusion Gene ORF analysis for NFE2L1-PNPO

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000362042ENST00000544840NFE2L1chr17

46134864

+PNPOchr17

46020672

+
In-frameENST00000362042ENST00000434554NFE2L1chr17

46134864

+PNPOchr17

46020672

+
In-frameENST00000362042ENST00000225573NFE2L1chr17

46134864

+PNPOchr17

46020672

+
5CDS-intronENST00000362042ENST00000534893NFE2L1chr17

46134864

+PNPOchr17

46020672

+
In-frameENST00000585291ENST00000544840NFE2L1chr17

46134864

+PNPOchr17

46020672

+
In-frameENST00000585291ENST00000434554NFE2L1chr17

46134864

+PNPOchr17

46020672

+
In-frameENST00000585291ENST00000225573NFE2L1chr17

46134864

+PNPOchr17

46020672

+
5CDS-intronENST00000585291ENST00000534893NFE2L1chr17

46134864

+PNPOchr17

46020672

+
In-frameENST00000357480ENST00000544840NFE2L1chr17

46134864

+PNPOchr17

46020672

+
In-frameENST00000357480ENST00000434554NFE2L1chr17

46134864

+PNPOchr17

46020672

+
In-frameENST00000357480ENST00000225573NFE2L1chr17

46134864

+PNPOchr17

46020672

+
5CDS-intronENST00000357480ENST00000534893NFE2L1chr17

46134864

+PNPOchr17

46020672

+
In-frameENST00000361665ENST00000544840NFE2L1chr17

46134864

+PNPOchr17

46020672

+
In-frameENST00000361665ENST00000434554NFE2L1chr17

46134864

+PNPOchr17

46020672

+
In-frameENST00000361665ENST00000225573NFE2L1chr17

46134864

+PNPOchr17

46020672

+
5CDS-intronENST00000361665ENST00000534893NFE2L1chr17

46134864

+PNPOchr17

46020672

+
intron-3CDSENST00000579481ENST00000544840NFE2L1chr17

46134864

+PNPOchr17

46020672

+
intron-3CDSENST00000579481ENST00000434554NFE2L1chr17

46134864

+PNPOchr17

46020672

+
intron-3CDSENST00000579481ENST00000225573NFE2L1chr17

46134864

+PNPOchr17

46020672

+
intron-intronENST00000579481ENST00000534893NFE2L1chr17

46134864

+PNPOchr17

46020672

+
In-frameENST00000582155ENST00000544840NFE2L1chr17

46134864

+PNPOchr17

46020672

+
In-frameENST00000582155ENST00000434554NFE2L1chr17

46134864

+PNPOchr17

46020672

+
In-frameENST00000582155ENST00000225573NFE2L1chr17

46134864

+PNPOchr17

46020672

+
5CDS-intronENST00000582155ENST00000534893NFE2L1chr17

46134864

+PNPOchr17

46020672

+
In-frameENST00000583378ENST00000544840NFE2L1chr17

46134864

+PNPOchr17

46020672

+
In-frameENST00000583378ENST00000434554NFE2L1chr17

46134864

+PNPOchr17

46020672

+
In-frameENST00000583378ENST00000225573NFE2L1chr17

46134864

+PNPOchr17

46020672

+
5CDS-intronENST00000583378ENST00000534893NFE2L1chr17

46134864

+PNPOchr17

46020672

+
In-frameENST00000536222ENST00000544840NFE2L1chr17

46134864

+PNPOchr17

46020672

+
In-frameENST00000536222ENST00000434554NFE2L1chr17

46134864

+PNPOchr17

46020672

+
In-frameENST00000536222ENST00000225573NFE2L1chr17

46134864

+PNPOchr17

46020672

+
5CDS-intronENST00000536222ENST00000534893NFE2L1chr17

46134864

+PNPOchr17

46020672

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000362042NFE2L1chr1746134864+ENST00000544840PNPOchr1746020672+254115886162181521
ENST00000362042NFE2L1chr1746134864+ENST00000434554PNPOchr1746020672+255515886162106496
ENST00000362042NFE2L1chr1746134864+ENST00000225573PNPOchr1746020672+374215886162235539
ENST00000585291NFE2L1chr1746134864+ENST00000544840PNPOchr1746020672+215011972911790499
ENST00000585291NFE2L1chr1746134864+ENST00000434554PNPOchr1746020672+216411972911715474
ENST00000585291NFE2L1chr1746134864+ENST00000225573PNPOchr1746020672+335111972911844517
ENST00000357480NFE2L1chr1746134864+ENST00000544840PNPOchr1746020672+244014876052080491
ENST00000357480NFE2L1chr1746134864+ENST00000434554PNPOchr1746020672+245414876052005466
ENST00000357480NFE2L1chr1746134864+ENST00000225573PNPOchr1746020672+364114876052134509
ENST00000361665NFE2L1chr1746134864+ENST00000544840PNPOchr1746020672+249615436042136510
ENST00000361665NFE2L1chr1746134864+ENST00000434554PNPOchr1746020672+251015436042061485
ENST00000361665NFE2L1chr1746134864+ENST00000225573PNPOchr1746020672+369715436042190528
ENST00000582155NFE2L1chr1746134864+ENST00000544840PNPOchr1746020672+1412459511052333
ENST00000582155NFE2L1chr1746134864+ENST00000434554PNPOchr1746020672+142645951977308
ENST00000582155NFE2L1chr1746134864+ENST00000225573PNPOchr1746020672+2613459511106351
ENST00000583378NFE2L1chr1746134864+ENST00000544840PNPOchr1746020672+1362409341002322
ENST00000583378NFE2L1chr1746134864+ENST00000434554PNPOchr1746020672+137640934927297
ENST00000583378NFE2L1chr1746134864+ENST00000225573PNPOchr1746020672+2563409341056340
ENST00000536222NFE2L1chr1746134864+ENST00000544840PNPOchr1746020672+17668132611406381
ENST00000536222NFE2L1chr1746134864+ENST00000434554PNPOchr1746020672+17808132611331356
ENST00000536222NFE2L1chr1746134864+ENST00000225573PNPOchr1746020672+29678132611460399

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000362042ENST00000544840NFE2L1chr1746134864+PNPOchr1746020672+0.0011786810.9988213
ENST00000362042ENST00000434554NFE2L1chr1746134864+PNPOchr1746020672+0.001333760.9986663
ENST00000362042ENST00000225573NFE2L1chr1746134864+PNPOchr1746020672+0.0005871910.9994128
ENST00000585291ENST00000544840NFE2L1chr1746134864+PNPOchr1746020672+0.0014742670.9985258
ENST00000585291ENST00000434554NFE2L1chr1746134864+PNPOchr1746020672+0.0018849630.99811506
ENST00000585291ENST00000225573NFE2L1chr1746134864+PNPOchr1746020672+0.000624950.99937505
ENST00000357480ENST00000544840NFE2L1chr1746134864+PNPOchr1746020672+0.0008699280.9991301
ENST00000357480ENST00000434554NFE2L1chr1746134864+PNPOchr1746020672+0.0011548840.9988451
ENST00000357480ENST00000225573NFE2L1chr1746134864+PNPOchr1746020672+0.0004673280.9995327
ENST00000361665ENST00000544840NFE2L1chr1746134864+PNPOchr1746020672+0.0008383320.9991617
ENST00000361665ENST00000434554NFE2L1chr1746134864+PNPOchr1746020672+0.0008144360.9991855
ENST00000361665ENST00000225573NFE2L1chr1746134864+PNPOchr1746020672+0.0005339480.9994661
ENST00000582155ENST00000544840NFE2L1chr1746134864+PNPOchr1746020672+0.0023515950.9976484
ENST00000582155ENST00000434554NFE2L1chr1746134864+PNPOchr1746020672+0.0020763180.9979236
ENST00000582155ENST00000225573NFE2L1chr1746134864+PNPOchr1746020672+0.0007614190.9992386
ENST00000583378ENST00000544840NFE2L1chr1746134864+PNPOchr1746020672+0.0037197180.99628025
ENST00000583378ENST00000434554NFE2L1chr1746134864+PNPOchr1746020672+0.004060170.99593985
ENST00000583378ENST00000225573NFE2L1chr1746134864+PNPOchr1746020672+0.0011404870.9988595
ENST00000536222ENST00000544840NFE2L1chr1746134864+PNPOchr1746020672+0.0112246770.9887754
ENST00000536222ENST00000434554NFE2L1chr1746134864+PNPOchr1746020672+0.0132018390.9867981
ENST00000536222ENST00000225573NFE2L1chr1746134864+PNPOchr1746020672+0.0046452710.9953548

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Fusion Genomic Features for NFE2L1-PNPO


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
NFE2L1chr1746134864+PNPOchr1746020671+0.0005726750.9994273
NFE2L1chr1746134864+PNPOchr1746020671+0.0005726750.9994273

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for NFE2L1-PNPO


check button Go to

FGviewer for the breakpoints of chr17:46134864-chr17:46020672

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
NFE2L1

Q14494

.
FUNCTION: [Endoplasmic reticulum membrane sensor NFE2L1]: Endoplasmic reticulum membrane sensor that translocates into the nucleus in response to various stresses to act as a transcription factor (PubMed:20932482, PubMed:24448410). Constitutes a precursor of the transcription factor NRF1 (By similarity). Able to detect various cellular stresses, such as cholesterol excess, oxidative stress or proteasome inhibition (PubMed:20932482). In response to stress, it is released from the endoplasmic reticulum membrane following cleavage by the protease DDI2 and translocates into the nucleus to form the transcription factor NRF1 (By similarity). Acts as a key sensor of cholesterol excess: in excess cholesterol conditions, the endoplasmic reticulum membrane form of the protein directly binds cholesterol via its CRAC motif, preventing cleavage and release of the transcription factor NRF1, thereby allowing expression of genes promoting cholesterol removal, such as CD36 (By similarity). Involved in proteasome homeostasis: in response to proteasome inhibition, it is released from the endoplasmic reticulum membrane, translocates to the nucleus and activates expression of genes encoding proteasome subunits (PubMed:20932482). {ECO:0000250|UniProtKB:Q61985, ECO:0000269|PubMed:20932482, ECO:0000269|PubMed:24448410}.; FUNCTION: [Transcription factor NRF1]: CNC-type bZIP family transcription factor that translocates to the nucleus and regulates expression of target genes in response to various stresses (PubMed:8932385, PubMed:9421508). Heterodimerizes with small-Maf proteins (MAFF, MAFG or MAFK) and binds DNA motifs including the antioxidant response elements (AREs), which regulate expression of genes involved in oxidative stress response (PubMed:8932385, PubMed:9421508). Activates or represses expression of target genes, depending on the context (PubMed:8932385, PubMed:9421508). Plays a key role in cholesterol homeostasis by acting as a sensor of cholesterol excess: in low cholesterol conditions, translocates into the nucleus and represses expression of genes involved in defense against cholesterol excess, such as CD36 (By similarity). In excess cholesterol conditions, the endoplasmic reticulum membrane form of the protein directly binds cholesterol via its CRAC motif, preventing cleavage and release of the transcription factor NRF1, thereby allowing expression of genes promoting cholesterol removal (By similarity). Critical for redox balance in response to oxidative stress: acts by binding the AREs motifs on promoters and mediating activation of oxidative stress response genes, such as GCLC, GCLM, GSS, MT1 and MT2 (By similarity). Plays an essential role during fetal liver hematopoiesis: probably has a protective function against oxidative stress and is involved in lipid homeostasis in the liver (By similarity). Involved in proteasome homeostasis: in response to proteasome inhibition, mediates the 'bounce-back' of proteasome subunits by translocating into the nucleus and activating expression of genes encoding proteasome subunits (PubMed:20932482). Also involved in regulating glucose flux (By similarity). Together with CEBPB; represses expression of DSPP during odontoblast differentiation (PubMed:15308669). In response to ascorbic acid induction, activates expression of SP7/Osterix in osteoblasts. {ECO:0000250|UniProtKB:Q61985, ECO:0000269|PubMed:15308669, ECO:0000269|PubMed:20932482, ECO:0000269|PubMed:8932385, ECO:0000269|PubMed:9421508}.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNFE2L1chr17:46134864chr17:46020672ENST00000357480+45125_288294.0743.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneNFE2L1chr17:46134864chr17:46020672ENST00000362042+56125_288324.0773.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneNFE2L1chr17:46134864chr17:46020672ENST00000585291+56125_288294.0743.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneNFE2L1chr17:46134864chr17:46020672ENST00000357480+45191_199294.0743.0RegionCholesterol recognition/amino acid consensus (CRAC) region
HgeneNFE2L1chr17:46134864chr17:46020672ENST00000362042+56191_199324.0773.0RegionCholesterol recognition/amino acid consensus (CRAC) region
HgeneNFE2L1chr17:46134864chr17:46020672ENST00000585291+56191_199294.0743.0RegionCholesterol recognition/amino acid consensus (CRAC) region
HgeneNFE2L1chr17:46134864chr17:46020672ENST00000357480+457_24294.0743.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
HgeneNFE2L1chr17:46134864chr17:46020672ENST00000362042+567_24324.0773.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
HgeneNFE2L1chr17:46134864chr17:46020672ENST00000585291+567_24294.0743.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
TgenePNPOchr17:46134864chr17:46020672ENST0000022557307110_11146.0262.0Nucleotide bindingFMN
TgenePNPOchr17:46134864chr17:46020672ENST0000022557307116_11746.0262.0Nucleotide bindingFMN
TgenePNPOchr17:46134864chr17:46020672ENST0000022557307174_17546.0262.0Nucleotide bindingFMN
TgenePNPOchr17:46134864chr17:46020672ENST000002255730795_9846.0262.0Nucleotide bindingFMN
TgenePNPOchr17:46134864chr17:46020672ENST0000022557307225_22746.0262.0RegionPyridoxal 5'-phosphate binding

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNFE2L1chr17:46134864chr17:46020672ENST00000357480+45496_517294.0743.0Compositional biasNote=Poly-Ser
HgeneNFE2L1chr17:46134864chr17:46020672ENST00000362042+56496_517324.0773.0Compositional biasNote=Poly-Ser
HgeneNFE2L1chr17:46134864chr17:46020672ENST00000585291+56496_517294.0743.0Compositional biasNote=Poly-Ser
HgeneNFE2L1chr17:46134864chr17:46020672ENST00000357480+45654_717294.0743.0DomainbZIP
HgeneNFE2L1chr17:46134864chr17:46020672ENST00000362042+56654_717324.0773.0DomainbZIP
HgeneNFE2L1chr17:46134864chr17:46020672ENST00000585291+56654_717294.0743.0DomainbZIP
HgeneNFE2L1chr17:46134864chr17:46020672ENST00000357480+45476_480294.0743.0MotifDestruction motif
HgeneNFE2L1chr17:46134864chr17:46020672ENST00000362042+56476_480324.0773.0MotifDestruction motif
HgeneNFE2L1chr17:46134864chr17:46020672ENST00000585291+56476_480294.0743.0MotifDestruction motif
HgeneNFE2L1chr17:46134864chr17:46020672ENST00000357480+45379_383294.0743.0RegionCPD
HgeneNFE2L1chr17:46134864chr17:46020672ENST00000357480+45656_675294.0743.0RegionBasic motif
HgeneNFE2L1chr17:46134864chr17:46020672ENST00000357480+45682_696294.0743.0RegionLeucine-zipper
HgeneNFE2L1chr17:46134864chr17:46020672ENST00000362042+56379_383324.0773.0RegionCPD
HgeneNFE2L1chr17:46134864chr17:46020672ENST00000362042+56656_675324.0773.0RegionBasic motif
HgeneNFE2L1chr17:46134864chr17:46020672ENST00000362042+56682_696324.0773.0RegionLeucine-zipper
HgeneNFE2L1chr17:46134864chr17:46020672ENST00000585291+56379_383294.0743.0RegionCPD
HgeneNFE2L1chr17:46134864chr17:46020672ENST00000585291+56656_675294.0743.0RegionBasic motif
HgeneNFE2L1chr17:46134864chr17:46020672ENST00000585291+56682_696294.0743.0RegionLeucine-zipper
TgenePNPOchr17:46134864chr17:46020672ENST000002255730742_4546.0262.0RegionPyridoxal 5'-phosphate binding


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Fusion Gene Sequence for NFE2L1-PNPO


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000362042_ENST00000544840_TCGA-EY-A2OQ-01A_NFE2L1_chr17_46134864_+_PNPO_chr17_46020672_length(transcript)=2541nt_BP=1588nt
AAGCGGAGGCTCCGAGCTCTAGGCCGGCCGGCGGTGGCGGCGGCGAGGCCGGGACTCGGGCTTAGGGCCTGCTGTGGAGGCAGCGGCGGA
CGCCGAGCTAAGCAGTTTCTCTGGAAACCCCCCTGGTAAGTGTGGAGGAGGCGGGACACTCTGACCCAAGACGAAAGGCCTGTAGCTCCA
GCCAAAGAAAATAAACCTTAGGAGGGAGAAGGAAAAAAAAAATCCATCAGCTGTTCCTGAGAACAGCCTGCATTGGAATCTACAGAGAGG
ACAACTAATGTGAGTGAGGAAGTGACTGTATGTGGACTGTGGAGAAAGTAAGTCACGTGGGCCCTTGAGGACCTGGACTGGGTTAGGAAC
AGTTGTACTTTCAGAGGTGAGGTGTCGAGAAGGGAAAGTGAATGTGGTCTGGAGTGTGTCCTTGGCCTTGGCTCCACAGGGTGTGCTTTC
CTCTGGGGCCGTCAGGGAGCTCATCCCTTGTGTTCTGCCAGGGTGGGGTACGGGGTTTGACACTGAGGAGGGTAACCTGCTGGCTGGAGC
GGCAGAGCAGTGGCCTTGATTTGTCTTTTGGAAGATTTTAAAAACCAAAAAGCATAAACATTCTGGTCCTTCAGCAATGCTTTCTCTGAA
GAAATACTTAACGGAAGGACTTCTCCAGTTCACCATTCTGCTGAGTTTGATTGGGGTACGGGTGGACGTGGATACTTACCTGACCTCACA
GCTTCCCCCACTCCGGGAGATCATCCTGGGGCCCAGTTCTGCCTATACTCAGACCCAGTTCCACAACCTGAGGAATACCTTGGATGGCTA
TGGTATCCACCCCAAGAGCATAGACCTGGACAATTACTTCACTGCCCGGCGGCTCCTCAGTCAGGTGAGGGCCCTGGACAGGTTCCAGGT
GCCAACCACTGAGGTAAATGCCTGGCTGGTTCACCGAGACCCAGAGGGGTCTGTCTCTGGCAGTCAGCCCAACTCAGGCCTCGCCCTCGA
GAGTTCCAGTGGCCTCCAAGATGTGACAGGCCCAGACAACGGGGTGCGAGAAAGCGAAACGGAGCAGGGATTCGGTGAAGATTTGGAGGA
TTTGGGGGCTGTAGCCCCCCCAGTCAGTGGAGACTTAACCAAAGAGGACATAGATCTGATTGACATCCTTTGGCGACAGGATATTGATCT
GGGGGCTGGGCGTGAGGTTTTTGACTATAGTCACCGCCAGAAGGAGCAGGATGTGGAGAAGGAGCTGCGAGATGGAGGCGAGCAGGACAC
CTGGGCAGGCGAGGGCGCGGAAGCTCTGGCACGGAACCTGCTAGTGGATGGAGAGACTGGGGAGAGCTTCCCTGCACAGGTGCCTAGTGG
GGAGGACCAGACGGCCCTGTCCCTGGAAGAGTGCCTTAGGCTGCTGGAAGCCACCTGCCCCTTTGGGGAGAATGCTGAGTTTCCAGCAGA
CATTTCCAGCATAACAGAAGCAGTGCCTAGTGAGAGTGAGCCCCCTGCTCTTCAAAACAACCTCTTGTCTCCTCTTCTGACCGGGACAGA
GTCACCATTTGATTTGGAACAGCAGTGGCAAGATCTCATGTCCATCATGGAAATGCAGGCATTTGAGGAGACTCATCTGACCTCCCTTGA
CCCAGTGAAACAGTTTGCTGCCTGGTTTGAGGAGGCTGTTCAGTGTCCTGACATAGGGGAAGCCAATGCCATGTGTCTGGCTACCTGCAC
CAGAGATGGAAAACCCTCTGCTCGCATGTTGCTGCTGAAGGGCTTCGGGAAAGATGGCTTCCGCTTCTTCACTAACTTCGAGAGTCGAAA
AGGAAAAGAGCTGGTGCGTGTGGAAGGCCCTGTGAAGAAACTGCCTGAGGAGGAGGCTGAGTGCTACTTCCACTCCCGCCCCAAGAGCAG
CCAGATTGGGGCTGTGGTCAGCCACCAGAGTTCTGTGATCCCTGATCGGGAGTATCTGAGAAAGAAAAATGAGGAACTGGAACAGCTCTA
CCAGGATCAAGAGGTGCCCAAGCCAAAATCCTGGGGTGGCTATGTCCTGTACCCTCAGGTGATGGAGTTCTGGCAAGGTCAAACCAACCG
CCTGCATGACCGGATAGTCTTTCGGCGGGGCCTACCCACAGGAGATTCCCCTTTGGGGCCCATGACCCACCGCGGGGAGGAAGACTGGCT
CTATGAGAGACTTGCACCTTAACTCTGGGACCTGCTGGCCCAGAGTGGAGCTAGGGCTAGGTGTCAAGAGAGGGTGTGGGATTGGGACCC
AGGCCCTTCTTTCTAAACTCAACCCATTTCCCTCCCTACCCCTTATCTTCAGGACTCTTCAGAGCTAATCCTCTAAGTTCTCTGTACTCA
GTTGGTTCTCAGTTAGCTGGTCAAGTGGAGTGTAATGGTGGCGTAGAGAATCACAAATGGAAAATAATTCCATAATTATTTTTTTGACCT
TGCCTATGATTGATTAGGATAGCTCCCTCTAGGGGTAGCAGCCGGTGTGACTCCCTTTCTGGTGACAGACAGGGCCCCAGCAGCCCTGTC

>In-frame_ENST00000362042_ENST00000544840_TCGA-EY-A2OQ-01A_NFE2L1_chr17_46134864_+_PNPO_chr17_46020672_length(amino acids)=521AA_start in transcript=616_stop in transcript=2181
MLSLKKYLTEGLLQFTILLSLIGVRVDVDTYLTSQLPPLREIILGPSSAYTQTQFHNLRNTLDGYGIHPKSIDLDNYFTARRLLSQVRAL
DRFQVPTTEVNAWLVHRDPEGSVSGSQPNSGLALESSSGLQDVTGPDNGVRESETEQGFGEDLEDLGAVAPPVSGDLTKEDIDLIDILWR
QDIDLGAGREVFDYSHRQKEQDVEKELRDGGEQDTWAGEGAEALARNLLVDGETGESFPAQVPSGEDQTALSLEECLRLLEATCPFGENA
EFPADISSITEAVPSESEPPALQNNLLSPLLTGTESPFDLEQQWQDLMSIMEMQAFEETHLTSLDPVKQFAAWFEEAVQCPDIGEANAMC
LATCTRDGKPSARMLLLKGFGKDGFRFFTNFESRKGKELVRVEGPVKKLPEEEAECYFHSRPKSSQIGAVVSHQSSVIPDREYLRKKNEE

--------------------------------------------------------------
>In-frame_ENST00000362042_ENST00000434554_TCGA-EY-A2OQ-01A_NFE2L1_chr17_46134864_+_PNPO_chr17_46020672_length(transcript)=2555nt_BP=1588nt
AAGCGGAGGCTCCGAGCTCTAGGCCGGCCGGCGGTGGCGGCGGCGAGGCCGGGACTCGGGCTTAGGGCCTGCTGTGGAGGCAGCGGCGGA
CGCCGAGCTAAGCAGTTTCTCTGGAAACCCCCCTGGTAAGTGTGGAGGAGGCGGGACACTCTGACCCAAGACGAAAGGCCTGTAGCTCCA
GCCAAAGAAAATAAACCTTAGGAGGGAGAAGGAAAAAAAAAATCCATCAGCTGTTCCTGAGAACAGCCTGCATTGGAATCTACAGAGAGG
ACAACTAATGTGAGTGAGGAAGTGACTGTATGTGGACTGTGGAGAAAGTAAGTCACGTGGGCCCTTGAGGACCTGGACTGGGTTAGGAAC
AGTTGTACTTTCAGAGGTGAGGTGTCGAGAAGGGAAAGTGAATGTGGTCTGGAGTGTGTCCTTGGCCTTGGCTCCACAGGGTGTGCTTTC
CTCTGGGGCCGTCAGGGAGCTCATCCCTTGTGTTCTGCCAGGGTGGGGTACGGGGTTTGACACTGAGGAGGGTAACCTGCTGGCTGGAGC
GGCAGAGCAGTGGCCTTGATTTGTCTTTTGGAAGATTTTAAAAACCAAAAAGCATAAACATTCTGGTCCTTCAGCAATGCTTTCTCTGAA
GAAATACTTAACGGAAGGACTTCTCCAGTTCACCATTCTGCTGAGTTTGATTGGGGTACGGGTGGACGTGGATACTTACCTGACCTCACA
GCTTCCCCCACTCCGGGAGATCATCCTGGGGCCCAGTTCTGCCTATACTCAGACCCAGTTCCACAACCTGAGGAATACCTTGGATGGCTA
TGGTATCCACCCCAAGAGCATAGACCTGGACAATTACTTCACTGCCCGGCGGCTCCTCAGTCAGGTGAGGGCCCTGGACAGGTTCCAGGT
GCCAACCACTGAGGTAAATGCCTGGCTGGTTCACCGAGACCCAGAGGGGTCTGTCTCTGGCAGTCAGCCCAACTCAGGCCTCGCCCTCGA
GAGTTCCAGTGGCCTCCAAGATGTGACAGGCCCAGACAACGGGGTGCGAGAAAGCGAAACGGAGCAGGGATTCGGTGAAGATTTGGAGGA
TTTGGGGGCTGTAGCCCCCCCAGTCAGTGGAGACTTAACCAAAGAGGACATAGATCTGATTGACATCCTTTGGCGACAGGATATTGATCT
GGGGGCTGGGCGTGAGGTTTTTGACTATAGTCACCGCCAGAAGGAGCAGGATGTGGAGAAGGAGCTGCGAGATGGAGGCGAGCAGGACAC
CTGGGCAGGCGAGGGCGCGGAAGCTCTGGCACGGAACCTGCTAGTGGATGGAGAGACTGGGGAGAGCTTCCCTGCACAGGTGCCTAGTGG
GGAGGACCAGACGGCCCTGTCCCTGGAAGAGTGCCTTAGGCTGCTGGAAGCCACCTGCCCCTTTGGGGAGAATGCTGAGTTTCCAGCAGA
CATTTCCAGCATAACAGAAGCAGTGCCTAGTGAGAGTGAGCCCCCTGCTCTTCAAAACAACCTCTTGTCTCCTCTTCTGACCGGGACAGA
GTCACCATTTGATTTGGAACAGCAGTGGCAAGATCTCATGTCCATCATGGAAATGCAGGCATTTGAGGAGACTCATCTGACCTCCCTTGA
CCCAGTGAAACAGTTTGCTGCCTGGTTTGAGGAGGCTGTTCAGTGTCCTGACATAGGGGAAGCCAATGCCATGTGTCTGGCTACCTGCAC
CAGAGATGGAAAACCCTCTGCTCGCATGTTGCTGCTGAAGGGCTTCGGGAAAGATGGCTTCCGCTTCTTCACTAACTTCGAGAGTCGAAA
AGGAAAAGAGCTGGACTCTAATCCCTTTGCTTCCCTTGTCTTCTACTGGGAGCCACTTAACCGTCAGTATCTGAGAAAGAAAAATGAGGA
ACTGGAACAGCTCTACCAGGATCAAGAGGTGCCCAAGCCAAAATCCTGGGGTGGCTATGTCCTGTACCCTCAGGTGATGGAGTTCTGGCA
AGGTCAAACCAACCGCCTGCATGACCGGATAGTCTTTCGGCGGGGCCTACCCACAGGAGATTCCCCTTTGGGGCCCATGACCCACCGCGG
GGAGGAAGACTGGCTCTATGAGAGACTTGCACCTTAACTCTGGGACCTGCTGGCCCAGAGTGGAGCTAGGGCTAGGTGTCAAGAGAGGGT
GTGGGATTGGGACCCAGGCCCTTCTTTCTAAACTCAACCCATTTCCCTCCCTACCCCTTATCTTCAGGACTCTTCAGAGCTAATCCTCTA
AGTTCTCTGTACTCAGTTGGTTCTCAGTTAGCTGGTCAAGTGGAGTGTAATGGTGGCGTAGAGAATCACAAATGGAAAATAATTCCATAA
TTATTTTTTTGACCTTGCCTATGATTGATTAGGATAGCTCCCTCTAGGGGTAGCAGCCGGTGTGACTCCCTTTCTGGTGACAGACAGGGC
CCCAGCAGCCCTGTCTGTTACCATGTGAGTCATACTGGCCAAAGCTTAGTCCTAGCATATGCACCTGAGCCAACCTGGCCAATCAGATTG

>In-frame_ENST00000362042_ENST00000434554_TCGA-EY-A2OQ-01A_NFE2L1_chr17_46134864_+_PNPO_chr17_46020672_length(amino acids)=496AA_start in transcript=616_stop in transcript=2106
MLSLKKYLTEGLLQFTILLSLIGVRVDVDTYLTSQLPPLREIILGPSSAYTQTQFHNLRNTLDGYGIHPKSIDLDNYFTARRLLSQVRAL
DRFQVPTTEVNAWLVHRDPEGSVSGSQPNSGLALESSSGLQDVTGPDNGVRESETEQGFGEDLEDLGAVAPPVSGDLTKEDIDLIDILWR
QDIDLGAGREVFDYSHRQKEQDVEKELRDGGEQDTWAGEGAEALARNLLVDGETGESFPAQVPSGEDQTALSLEECLRLLEATCPFGENA
EFPADISSITEAVPSESEPPALQNNLLSPLLTGTESPFDLEQQWQDLMSIMEMQAFEETHLTSLDPVKQFAAWFEEAVQCPDIGEANAMC
LATCTRDGKPSARMLLLKGFGKDGFRFFTNFESRKGKELDSNPFASLVFYWEPLNRQYLRKKNEELEQLYQDQEVPKPKSWGGYVLYPQV

--------------------------------------------------------------
>In-frame_ENST00000362042_ENST00000225573_TCGA-EY-A2OQ-01A_NFE2L1_chr17_46134864_+_PNPO_chr17_46020672_length(transcript)=3742nt_BP=1588nt
AAGCGGAGGCTCCGAGCTCTAGGCCGGCCGGCGGTGGCGGCGGCGAGGCCGGGACTCGGGCTTAGGGCCTGCTGTGGAGGCAGCGGCGGA
CGCCGAGCTAAGCAGTTTCTCTGGAAACCCCCCTGGTAAGTGTGGAGGAGGCGGGACACTCTGACCCAAGACGAAAGGCCTGTAGCTCCA
GCCAAAGAAAATAAACCTTAGGAGGGAGAAGGAAAAAAAAAATCCATCAGCTGTTCCTGAGAACAGCCTGCATTGGAATCTACAGAGAGG
ACAACTAATGTGAGTGAGGAAGTGACTGTATGTGGACTGTGGAGAAAGTAAGTCACGTGGGCCCTTGAGGACCTGGACTGGGTTAGGAAC
AGTTGTACTTTCAGAGGTGAGGTGTCGAGAAGGGAAAGTGAATGTGGTCTGGAGTGTGTCCTTGGCCTTGGCTCCACAGGGTGTGCTTTC
CTCTGGGGCCGTCAGGGAGCTCATCCCTTGTGTTCTGCCAGGGTGGGGTACGGGGTTTGACACTGAGGAGGGTAACCTGCTGGCTGGAGC
GGCAGAGCAGTGGCCTTGATTTGTCTTTTGGAAGATTTTAAAAACCAAAAAGCATAAACATTCTGGTCCTTCAGCAATGCTTTCTCTGAA
GAAATACTTAACGGAAGGACTTCTCCAGTTCACCATTCTGCTGAGTTTGATTGGGGTACGGGTGGACGTGGATACTTACCTGACCTCACA
GCTTCCCCCACTCCGGGAGATCATCCTGGGGCCCAGTTCTGCCTATACTCAGACCCAGTTCCACAACCTGAGGAATACCTTGGATGGCTA
TGGTATCCACCCCAAGAGCATAGACCTGGACAATTACTTCACTGCCCGGCGGCTCCTCAGTCAGGTGAGGGCCCTGGACAGGTTCCAGGT
GCCAACCACTGAGGTAAATGCCTGGCTGGTTCACCGAGACCCAGAGGGGTCTGTCTCTGGCAGTCAGCCCAACTCAGGCCTCGCCCTCGA
GAGTTCCAGTGGCCTCCAAGATGTGACAGGCCCAGACAACGGGGTGCGAGAAAGCGAAACGGAGCAGGGATTCGGTGAAGATTTGGAGGA
TTTGGGGGCTGTAGCCCCCCCAGTCAGTGGAGACTTAACCAAAGAGGACATAGATCTGATTGACATCCTTTGGCGACAGGATATTGATCT
GGGGGCTGGGCGTGAGGTTTTTGACTATAGTCACCGCCAGAAGGAGCAGGATGTGGAGAAGGAGCTGCGAGATGGAGGCGAGCAGGACAC
CTGGGCAGGCGAGGGCGCGGAAGCTCTGGCACGGAACCTGCTAGTGGATGGAGAGACTGGGGAGAGCTTCCCTGCACAGGTGCCTAGTGG
GGAGGACCAGACGGCCCTGTCCCTGGAAGAGTGCCTTAGGCTGCTGGAAGCCACCTGCCCCTTTGGGGAGAATGCTGAGTTTCCAGCAGA
CATTTCCAGCATAACAGAAGCAGTGCCTAGTGAGAGTGAGCCCCCTGCTCTTCAAAACAACCTCTTGTCTCCTCTTCTGACCGGGACAGA
GTCACCATTTGATTTGGAACAGCAGTGGCAAGATCTCATGTCCATCATGGAAATGCAGGCATTTGAGGAGACTCATCTGACCTCCCTTGA
CCCAGTGAAACAGTTTGCTGCCTGGTTTGAGGAGGCTGTTCAGTGTCCTGACATAGGGGAAGCCAATGCCATGTGTCTGGCTACCTGCAC
CAGAGATGGAAAACCCTCTGCTCGCATGTTGCTGCTGAAGGGCTTCGGGAAAGATGGCTTCCGCTTCTTCACTAACTTCGAGAGTCGAAA
AGGAAAAGAGCTGGACTCTAATCCCTTTGCTTCCCTTGTCTTCTACTGGGAGCCACTTAACCGTCAGGTGCGTGTGGAAGGCCCTGTGAA
GAAACTGCCTGAGGAGGAGGCTGAGTGCTACTTCCACTCCCGCCCCAAGAGCAGCCAGATTGGGGCTGTGGTCAGCCACCAGAGTTCTGT
GATCCCTGATCGGGAGTATCTGAGAAAGAAAAATGAGGAACTGGAACAGCTCTACCAGGATCAAGAGGTGCCCAAGCCAAAATCCTGGGG
TGGCTATGTCCTGTACCCTCAGGTGATGGAGTTCTGGCAAGGTCAAACCAACCGCCTGCATGACCGGATAGTCTTTCGGCGGGGCCTACC
CACAGGAGATTCCCCTTTGGGGCCCATGACCCACCGCGGGGAGGAAGACTGGCTCTATGAGAGACTTGCACCTTAACTCTGGGACCTGCT
GGCCCAGAGTGGAGCTAGGGCTAGGTGTCAAGAGAGGGTGTGGGATTGGGACCCAGGCCCTTCTTTCTAAACTCAACCCATTTCCCTCCC
TACCCCTTATCTTCAGGACTCTTCAGAGCTAATCCTCTAAGTTCTCTGTACTCAGTTGGTTCTCAGTTAGCTGGTCAAGTGGAGTGTAAT
GGTGGCGTAGAGAATCACAAATGGAAAATAATTCCATAATTATTTTTTTGACCTTGCCTATGATTGATTAGGATAGCTCCCTCTAGGGGT
AGCAGCCGGTGTGACTCCCTTTCTGGTGACAGACAGGGCCCCAGCAGCCCTGTCTGTTACCATGTGAGTCATACTGGCCAAAGCTTAGTC
CTAGCATATGCACCTGAGCCAACCTGGCCAATCAGATTGTTTTGTCAATAATTTGAAATTTGAACTGGAGAGATCCAGAACCTTGGGAGT
CATTAAAGCCAAGTCATTCATAGCAGCCAGGAAACAATAGGAACCAAAAGCCTCTGCCTGCTGCTATTGCAATTCCCAGGATCTCTCCTT
CCCTGGATCCCTCCCTCCCAGGTCTGGGCTGTGCAGTTCCTCCCCCTGCCTTAAAACACCCCACTATCTCTGTAAAGTCTCTCTCTCTCT
TTTTTTTTTTTTTACTTAATCTAGCTAGAATCTATTTCTGTTGATTACAACTTAACTAACTCATTTACGGATAGGACTTTTTTTTTTCTT
TTTTTCTTTTTTCTTTTCTTTTTTTTTTTTGAGATGGAGTCTCACTCTGTCACCCAGGCTGGAGTGCAGTGGTGTGATCTTGGCTCACTG
CAACCTCTGCCTCCCAGGTTCAAGCAATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGACTACAGGCACACGCCACCACACCCAACTAAT
TTTTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTGGCCAGGATTGTCTCCATCTCTTGACCTTGTGATCCACCCACCTCAGCCTCCC
AAAGTGCTGGGATTACAGGCATGAGCCACCACACCCAGCGAGACGGGGTTTCATTATGTTGGCCAGGCTGGTCTCCAACTCCTGACCTAA
AGTGATCTGCCCGCCTTGGCCTCCCAAAGTGCTGGGATTACAGACATGAGCCACCACGCTTGGCCGGGATAGTATATTTTTATAGCACTT
CCCCTACTGATTGCTGCCTTCTCTGTGGCTACAAGGGACCCACAGAATTACAGGGAAGTTACAGGGAAGCAGGTTTCATCTCAATATTGG
GAGAGATTTCAAACAATCACACCTGCCTGAGAAGGAGTGGGCTGTCACTAGGAATTTTTATTCCCAGTCCGTCAGGAATTTTGTAGAAGG
GCTTCATGTGCTGGTACCAATAGGACAGGAAGATTTTAATCAGCTTTACTATCTATGTTTTTTTATGGAAACTGTGTGTATGTATACATA

>In-frame_ENST00000362042_ENST00000225573_TCGA-EY-A2OQ-01A_NFE2L1_chr17_46134864_+_PNPO_chr17_46020672_length(amino acids)=539AA_start in transcript=616_stop in transcript=2235
MLSLKKYLTEGLLQFTILLSLIGVRVDVDTYLTSQLPPLREIILGPSSAYTQTQFHNLRNTLDGYGIHPKSIDLDNYFTARRLLSQVRAL
DRFQVPTTEVNAWLVHRDPEGSVSGSQPNSGLALESSSGLQDVTGPDNGVRESETEQGFGEDLEDLGAVAPPVSGDLTKEDIDLIDILWR
QDIDLGAGREVFDYSHRQKEQDVEKELRDGGEQDTWAGEGAEALARNLLVDGETGESFPAQVPSGEDQTALSLEECLRLLEATCPFGENA
EFPADISSITEAVPSESEPPALQNNLLSPLLTGTESPFDLEQQWQDLMSIMEMQAFEETHLTSLDPVKQFAAWFEEAVQCPDIGEANAMC
LATCTRDGKPSARMLLLKGFGKDGFRFFTNFESRKGKELDSNPFASLVFYWEPLNRQVRVEGPVKKLPEEEAECYFHSRPKSSQIGAVVS

--------------------------------------------------------------
>In-frame_ENST00000585291_ENST00000544840_TCGA-EY-A2OQ-01A_NFE2L1_chr17_46134864_+_PNPO_chr17_46020672_length(transcript)=2150nt_BP=1197nt
GGAGGCTCCGAGCTCTAGGCCGGCCGGCGGTGGCGGCGGCGAGGCCGGGACTCGGGCTTAGGGCCTGCTGTGGAGGCAGCGGCGGACGCC
GAGCTAAGCAGTTTCTCTGGAAACCCCCCTGGTAAGTGTGGAGGAGGCGGGACACTCTGACCCAAGACGAAAGGCCTGTAGCTCCAGCCA
AAGAAAATAAACCTTAGGAGGGAGAAGGAAAAAAAAAATCCATCAGCTGTTCCTGAGAACAGCCTGCATTGGAATCTACAGAGAGGACAA
CTAATGTGAGTGAGGAAGTGACTGTATGTGGACTGTGGAGAAACAATGCTTTCTCTGAAGAAATACTTAACGGAAGGACTTCTCCAGTTC
ACCATTCTGCTGAGTTTGATTGGGGTACGGGTGGACGTGGATACTTACCTGACCTCACAGCTTCCCCCACTCCGGGAGATCATCCTGGGG
CCCAGTTCTGCCTATACTCAGACCCAGTTCCACAACCTGAGGAATACCTTGGATGGCTATGGTATCCACCCCAAGAGCATAGACCTGGAC
AATTACTTCACTGCCCGGCGGCTCCTCAGTCAGGTGAGGGCCCTGGACAGGTTCCAGGTGCCAACCACTGAGGTAAATGCCTGGCTGGTT
CACCGAGACCCAGAGGGGTCTGTCTCTGGCAGTCAGCCCAACTCAGGCCTCGCCCTCGAGAGTTCCAGTGGCCTCCAAGATGTGACAGGC
CCAGACAACGGGGTGCGAGAAAGCGAAACGGAGCAGGGATTCGGTGAAGATTTGGAGGATTTGGGGGCTGTAGCCCCCCCAGTCAGTGGA
GACTTAACCAAAGAGGACATAGATCTGATTGACATCCTTTGGCGACAGGATATTGATCTGGGGGCTGGGCGTGAGGTTTTTGACTATAGT
CACCGCCAGAAGGAGCAGGATGTGGAGAAGGAGCTGCGAGATGGAGGCGAGCAGGACACCTGGGCAGGCGAGGGCGCGGAAGCTCTGGCA
CGGAACCTGCTAGTGGATGGAGAGACTGGGGAGAGCTTCCCTGCACAGTTTCCAGCAGACATTTCCAGCATAACAGAAGCAGTGCCTAGT
GAGAGTGAGCCCCCTGCTCTTCAAAACAACCTCTTGTCTCCTCTTCTGACCGGGACAGAGTCACCATTTGATTTGGAACAGCAGTGGCAA
GATCTCATGTCCATCATGGAAATGCAGGCATTTGAGGAGACTCATCTGACCTCCCTTGACCCAGTGAAACAGTTTGCTGCCTGGTTTGAG
GAGGCTGTTCAGTGTCCTGACATAGGGGAAGCCAATGCCATGTGTCTGGCTACCTGCACCAGAGATGGAAAACCCTCTGCTCGCATGTTG
CTGCTGAAGGGCTTCGGGAAAGATGGCTTCCGCTTCTTCACTAACTTCGAGAGTCGAAAAGGAAAAGAGCTGGTGCGTGTGGAAGGCCCT
GTGAAGAAACTGCCTGAGGAGGAGGCTGAGTGCTACTTCCACTCCCGCCCCAAGAGCAGCCAGATTGGGGCTGTGGTCAGCCACCAGAGT
TCTGTGATCCCTGATCGGGAGTATCTGAGAAAGAAAAATGAGGAACTGGAACAGCTCTACCAGGATCAAGAGGTGCCCAAGCCAAAATCC
TGGGGTGGCTATGTCCTGTACCCTCAGGTGATGGAGTTCTGGCAAGGTCAAACCAACCGCCTGCATGACCGGATAGTCTTTCGGCGGGGC
CTACCCACAGGAGATTCCCCTTTGGGGCCCATGACCCACCGCGGGGAGGAAGACTGGCTCTATGAGAGACTTGCACCTTAACTCTGGGAC
CTGCTGGCCCAGAGTGGAGCTAGGGCTAGGTGTCAAGAGAGGGTGTGGGATTGGGACCCAGGCCCTTCTTTCTAAACTCAACCCATTTCC
CTCCCTACCCCTTATCTTCAGGACTCTTCAGAGCTAATCCTCTAAGTTCTCTGTACTCAGTTGGTTCTCAGTTAGCTGGTCAAGTGGAGT
GTAATGGTGGCGTAGAGAATCACAAATGGAAAATAATTCCATAATTATTTTTTTGACCTTGCCTATGATTGATTAGGATAGCTCCCTCTA

>In-frame_ENST00000585291_ENST00000544840_TCGA-EY-A2OQ-01A_NFE2L1_chr17_46134864_+_PNPO_chr17_46020672_length(amino acids)=499AA_start in transcript=291_stop in transcript=1790
MYVDCGETMLSLKKYLTEGLLQFTILLSLIGVRVDVDTYLTSQLPPLREIILGPSSAYTQTQFHNLRNTLDGYGIHPKSIDLDNYFTARR
LLSQVRALDRFQVPTTEVNAWLVHRDPEGSVSGSQPNSGLALESSSGLQDVTGPDNGVRESETEQGFGEDLEDLGAVAPPVSGDLTKEDI
DLIDILWRQDIDLGAGREVFDYSHRQKEQDVEKELRDGGEQDTWAGEGAEALARNLLVDGETGESFPAQFPADISSITEAVPSESEPPAL
QNNLLSPLLTGTESPFDLEQQWQDLMSIMEMQAFEETHLTSLDPVKQFAAWFEEAVQCPDIGEANAMCLATCTRDGKPSARMLLLKGFGK
DGFRFFTNFESRKGKELVRVEGPVKKLPEEEAECYFHSRPKSSQIGAVVSHQSSVIPDREYLRKKNEELEQLYQDQEVPKPKSWGGYVLY

--------------------------------------------------------------
>In-frame_ENST00000585291_ENST00000434554_TCGA-EY-A2OQ-01A_NFE2L1_chr17_46134864_+_PNPO_chr17_46020672_length(transcript)=2164nt_BP=1197nt
GGAGGCTCCGAGCTCTAGGCCGGCCGGCGGTGGCGGCGGCGAGGCCGGGACTCGGGCTTAGGGCCTGCTGTGGAGGCAGCGGCGGACGCC
GAGCTAAGCAGTTTCTCTGGAAACCCCCCTGGTAAGTGTGGAGGAGGCGGGACACTCTGACCCAAGACGAAAGGCCTGTAGCTCCAGCCA
AAGAAAATAAACCTTAGGAGGGAGAAGGAAAAAAAAAATCCATCAGCTGTTCCTGAGAACAGCCTGCATTGGAATCTACAGAGAGGACAA
CTAATGTGAGTGAGGAAGTGACTGTATGTGGACTGTGGAGAAACAATGCTTTCTCTGAAGAAATACTTAACGGAAGGACTTCTCCAGTTC
ACCATTCTGCTGAGTTTGATTGGGGTACGGGTGGACGTGGATACTTACCTGACCTCACAGCTTCCCCCACTCCGGGAGATCATCCTGGGG
CCCAGTTCTGCCTATACTCAGACCCAGTTCCACAACCTGAGGAATACCTTGGATGGCTATGGTATCCACCCCAAGAGCATAGACCTGGAC
AATTACTTCACTGCCCGGCGGCTCCTCAGTCAGGTGAGGGCCCTGGACAGGTTCCAGGTGCCAACCACTGAGGTAAATGCCTGGCTGGTT
CACCGAGACCCAGAGGGGTCTGTCTCTGGCAGTCAGCCCAACTCAGGCCTCGCCCTCGAGAGTTCCAGTGGCCTCCAAGATGTGACAGGC
CCAGACAACGGGGTGCGAGAAAGCGAAACGGAGCAGGGATTCGGTGAAGATTTGGAGGATTTGGGGGCTGTAGCCCCCCCAGTCAGTGGA
GACTTAACCAAAGAGGACATAGATCTGATTGACATCCTTTGGCGACAGGATATTGATCTGGGGGCTGGGCGTGAGGTTTTTGACTATAGT
CACCGCCAGAAGGAGCAGGATGTGGAGAAGGAGCTGCGAGATGGAGGCGAGCAGGACACCTGGGCAGGCGAGGGCGCGGAAGCTCTGGCA
CGGAACCTGCTAGTGGATGGAGAGACTGGGGAGAGCTTCCCTGCACAGTTTCCAGCAGACATTTCCAGCATAACAGAAGCAGTGCCTAGT
GAGAGTGAGCCCCCTGCTCTTCAAAACAACCTCTTGTCTCCTCTTCTGACCGGGACAGAGTCACCATTTGATTTGGAACAGCAGTGGCAA
GATCTCATGTCCATCATGGAAATGCAGGCATTTGAGGAGACTCATCTGACCTCCCTTGACCCAGTGAAACAGTTTGCTGCCTGGTTTGAG
GAGGCTGTTCAGTGTCCTGACATAGGGGAAGCCAATGCCATGTGTCTGGCTACCTGCACCAGAGATGGAAAACCCTCTGCTCGCATGTTG
CTGCTGAAGGGCTTCGGGAAAGATGGCTTCCGCTTCTTCACTAACTTCGAGAGTCGAAAAGGAAAAGAGCTGGACTCTAATCCCTTTGCT
TCCCTTGTCTTCTACTGGGAGCCACTTAACCGTCAGTATCTGAGAAAGAAAAATGAGGAACTGGAACAGCTCTACCAGGATCAAGAGGTG
CCCAAGCCAAAATCCTGGGGTGGCTATGTCCTGTACCCTCAGGTGATGGAGTTCTGGCAAGGTCAAACCAACCGCCTGCATGACCGGATA
GTCTTTCGGCGGGGCCTACCCACAGGAGATTCCCCTTTGGGGCCCATGACCCACCGCGGGGAGGAAGACTGGCTCTATGAGAGACTTGCA
CCTTAACTCTGGGACCTGCTGGCCCAGAGTGGAGCTAGGGCTAGGTGTCAAGAGAGGGTGTGGGATTGGGACCCAGGCCCTTCTTTCTAA
ACTCAACCCATTTCCCTCCCTACCCCTTATCTTCAGGACTCTTCAGAGCTAATCCTCTAAGTTCTCTGTACTCAGTTGGTTCTCAGTTAG
CTGGTCAAGTGGAGTGTAATGGTGGCGTAGAGAATCACAAATGGAAAATAATTCCATAATTATTTTTTTGACCTTGCCTATGATTGATTA
GGATAGCTCCCTCTAGGGGTAGCAGCCGGTGTGACTCCCTTTCTGGTGACAGACAGGGCCCCAGCAGCCCTGTCTGTTACCATGTGAGTC
ATACTGGCCAAAGCTTAGTCCTAGCATATGCACCTGAGCCAACCTGGCCAATCAGATTGTTTTGTCAATAATTTGAAATTTGAACTGGAG

>In-frame_ENST00000585291_ENST00000434554_TCGA-EY-A2OQ-01A_NFE2L1_chr17_46134864_+_PNPO_chr17_46020672_length(amino acids)=474AA_start in transcript=291_stop in transcript=1715
MYVDCGETMLSLKKYLTEGLLQFTILLSLIGVRVDVDTYLTSQLPPLREIILGPSSAYTQTQFHNLRNTLDGYGIHPKSIDLDNYFTARR
LLSQVRALDRFQVPTTEVNAWLVHRDPEGSVSGSQPNSGLALESSSGLQDVTGPDNGVRESETEQGFGEDLEDLGAVAPPVSGDLTKEDI
DLIDILWRQDIDLGAGREVFDYSHRQKEQDVEKELRDGGEQDTWAGEGAEALARNLLVDGETGESFPAQFPADISSITEAVPSESEPPAL
QNNLLSPLLTGTESPFDLEQQWQDLMSIMEMQAFEETHLTSLDPVKQFAAWFEEAVQCPDIGEANAMCLATCTRDGKPSARMLLLKGFGK
DGFRFFTNFESRKGKELDSNPFASLVFYWEPLNRQYLRKKNEELEQLYQDQEVPKPKSWGGYVLYPQVMEFWQGQTNRLHDRIVFRRGLP

--------------------------------------------------------------
>In-frame_ENST00000585291_ENST00000225573_TCGA-EY-A2OQ-01A_NFE2L1_chr17_46134864_+_PNPO_chr17_46020672_length(transcript)=3351nt_BP=1197nt
GGAGGCTCCGAGCTCTAGGCCGGCCGGCGGTGGCGGCGGCGAGGCCGGGACTCGGGCTTAGGGCCTGCTGTGGAGGCAGCGGCGGACGCC
GAGCTAAGCAGTTTCTCTGGAAACCCCCCTGGTAAGTGTGGAGGAGGCGGGACACTCTGACCCAAGACGAAAGGCCTGTAGCTCCAGCCA
AAGAAAATAAACCTTAGGAGGGAGAAGGAAAAAAAAAATCCATCAGCTGTTCCTGAGAACAGCCTGCATTGGAATCTACAGAGAGGACAA
CTAATGTGAGTGAGGAAGTGACTGTATGTGGACTGTGGAGAAACAATGCTTTCTCTGAAGAAATACTTAACGGAAGGACTTCTCCAGTTC
ACCATTCTGCTGAGTTTGATTGGGGTACGGGTGGACGTGGATACTTACCTGACCTCACAGCTTCCCCCACTCCGGGAGATCATCCTGGGG
CCCAGTTCTGCCTATACTCAGACCCAGTTCCACAACCTGAGGAATACCTTGGATGGCTATGGTATCCACCCCAAGAGCATAGACCTGGAC
AATTACTTCACTGCCCGGCGGCTCCTCAGTCAGGTGAGGGCCCTGGACAGGTTCCAGGTGCCAACCACTGAGGTAAATGCCTGGCTGGTT
CACCGAGACCCAGAGGGGTCTGTCTCTGGCAGTCAGCCCAACTCAGGCCTCGCCCTCGAGAGTTCCAGTGGCCTCCAAGATGTGACAGGC
CCAGACAACGGGGTGCGAGAAAGCGAAACGGAGCAGGGATTCGGTGAAGATTTGGAGGATTTGGGGGCTGTAGCCCCCCCAGTCAGTGGA
GACTTAACCAAAGAGGACATAGATCTGATTGACATCCTTTGGCGACAGGATATTGATCTGGGGGCTGGGCGTGAGGTTTTTGACTATAGT
CACCGCCAGAAGGAGCAGGATGTGGAGAAGGAGCTGCGAGATGGAGGCGAGCAGGACACCTGGGCAGGCGAGGGCGCGGAAGCTCTGGCA
CGGAACCTGCTAGTGGATGGAGAGACTGGGGAGAGCTTCCCTGCACAGTTTCCAGCAGACATTTCCAGCATAACAGAAGCAGTGCCTAGT
GAGAGTGAGCCCCCTGCTCTTCAAAACAACCTCTTGTCTCCTCTTCTGACCGGGACAGAGTCACCATTTGATTTGGAACAGCAGTGGCAA
GATCTCATGTCCATCATGGAAATGCAGGCATTTGAGGAGACTCATCTGACCTCCCTTGACCCAGTGAAACAGTTTGCTGCCTGGTTTGAG
GAGGCTGTTCAGTGTCCTGACATAGGGGAAGCCAATGCCATGTGTCTGGCTACCTGCACCAGAGATGGAAAACCCTCTGCTCGCATGTTG
CTGCTGAAGGGCTTCGGGAAAGATGGCTTCCGCTTCTTCACTAACTTCGAGAGTCGAAAAGGAAAAGAGCTGGACTCTAATCCCTTTGCT
TCCCTTGTCTTCTACTGGGAGCCACTTAACCGTCAGGTGCGTGTGGAAGGCCCTGTGAAGAAACTGCCTGAGGAGGAGGCTGAGTGCTAC
TTCCACTCCCGCCCCAAGAGCAGCCAGATTGGGGCTGTGGTCAGCCACCAGAGTTCTGTGATCCCTGATCGGGAGTATCTGAGAAAGAAA
AATGAGGAACTGGAACAGCTCTACCAGGATCAAGAGGTGCCCAAGCCAAAATCCTGGGGTGGCTATGTCCTGTACCCTCAGGTGATGGAG
TTCTGGCAAGGTCAAACCAACCGCCTGCATGACCGGATAGTCTTTCGGCGGGGCCTACCCACAGGAGATTCCCCTTTGGGGCCCATGACC
CACCGCGGGGAGGAAGACTGGCTCTATGAGAGACTTGCACCTTAACTCTGGGACCTGCTGGCCCAGAGTGGAGCTAGGGCTAGGTGTCAA
GAGAGGGTGTGGGATTGGGACCCAGGCCCTTCTTTCTAAACTCAACCCATTTCCCTCCCTACCCCTTATCTTCAGGACTCTTCAGAGCTA
ATCCTCTAAGTTCTCTGTACTCAGTTGGTTCTCAGTTAGCTGGTCAAGTGGAGTGTAATGGTGGCGTAGAGAATCACAAATGGAAAATAA
TTCCATAATTATTTTTTTGACCTTGCCTATGATTGATTAGGATAGCTCCCTCTAGGGGTAGCAGCCGGTGTGACTCCCTTTCTGGTGACA
GACAGGGCCCCAGCAGCCCTGTCTGTTACCATGTGAGTCATACTGGCCAAAGCTTAGTCCTAGCATATGCACCTGAGCCAACCTGGCCAA
TCAGATTGTTTTGTCAATAATTTGAAATTTGAACTGGAGAGATCCAGAACCTTGGGAGTCATTAAAGCCAAGTCATTCATAGCAGCCAGG
AAACAATAGGAACCAAAAGCCTCTGCCTGCTGCTATTGCAATTCCCAGGATCTCTCCTTCCCTGGATCCCTCCCTCCCAGGTCTGGGCTG
TGCAGTTCCTCCCCCTGCCTTAAAACACCCCACTATCTCTGTAAAGTCTCTCTCTCTCTTTTTTTTTTTTTTACTTAATCTAGCTAGAAT
CTATTTCTGTTGATTACAACTTAACTAACTCATTTACGGATAGGACTTTTTTTTTTCTTTTTTTCTTTTTTCTTTTCTTTTTTTTTTTTG
AGATGGAGTCTCACTCTGTCACCCAGGCTGGAGTGCAGTGGTGTGATCTTGGCTCACTGCAACCTCTGCCTCCCAGGTTCAAGCAATTCT
CCTGCCTCAGCCTCCCAAGTAGCTGGGACTACAGGCACACGCCACCACACCCAACTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCAC
CATGTTGGCCAGGATTGTCTCCATCTCTTGACCTTGTGATCCACCCACCTCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCA
CACCCAGCGAGACGGGGTTTCATTATGTTGGCCAGGCTGGTCTCCAACTCCTGACCTAAAGTGATCTGCCCGCCTTGGCCTCCCAAAGTG
CTGGGATTACAGACATGAGCCACCACGCTTGGCCGGGATAGTATATTTTTATAGCACTTCCCCTACTGATTGCTGCCTTCTCTGTGGCTA
CAAGGGACCCACAGAATTACAGGGAAGTTACAGGGAAGCAGGTTTCATCTCAATATTGGGAGAGATTTCAAACAATCACACCTGCCTGAG
AAGGAGTGGGCTGTCACTAGGAATTTTTATTCCCAGTCCGTCAGGAATTTTGTAGAAGGGCTTCATGTGCTGGTACCAATAGGACAGGAA
GATTTTAATCAGCTTTACTATCTATGTTTTTTTATGGAAACTGTGTGTATGTATACATACATTTTCCAAAAAGAAAAATTAAATGATTAT

>In-frame_ENST00000585291_ENST00000225573_TCGA-EY-A2OQ-01A_NFE2L1_chr17_46134864_+_PNPO_chr17_46020672_length(amino acids)=517AA_start in transcript=291_stop in transcript=1844
MYVDCGETMLSLKKYLTEGLLQFTILLSLIGVRVDVDTYLTSQLPPLREIILGPSSAYTQTQFHNLRNTLDGYGIHPKSIDLDNYFTARR
LLSQVRALDRFQVPTTEVNAWLVHRDPEGSVSGSQPNSGLALESSSGLQDVTGPDNGVRESETEQGFGEDLEDLGAVAPPVSGDLTKEDI
DLIDILWRQDIDLGAGREVFDYSHRQKEQDVEKELRDGGEQDTWAGEGAEALARNLLVDGETGESFPAQFPADISSITEAVPSESEPPAL
QNNLLSPLLTGTESPFDLEQQWQDLMSIMEMQAFEETHLTSLDPVKQFAAWFEEAVQCPDIGEANAMCLATCTRDGKPSARMLLLKGFGK
DGFRFFTNFESRKGKELDSNPFASLVFYWEPLNRQVRVEGPVKKLPEEEAECYFHSRPKSSQIGAVVSHQSSVIPDREYLRKKNEELEQL

--------------------------------------------------------------
>In-frame_ENST00000357480_ENST00000544840_TCGA-EY-A2OQ-01A_NFE2L1_chr17_46134864_+_PNPO_chr17_46020672_length(transcript)=2440nt_BP=1487nt
CCGAGCTCTAGGCCGGCCGGCGGTGGCGGCGGCGAGGCCGGGACTCGGGCTTAGGGCCTGCTGTGGAGGCAGCGGCGGACGCCGAGCTAA
GCAGTTTCTCTGGAAACCCCCCTGGTAAGTGTGGAGGAGGCGGGACACTCTGACCCAAGACGAAAGGCCTGTAGCTCCAGCCAAAGAAAA
TAAACCTTAGGAGGGAGAAGGAAAAAAAAAATCCATCAGCTGTTCCTGAGAACAGCCTGCATTGGAATCTACAGAGAGGACAACTAATGT
GAGTGAGGAAGTGACTGTATGTGGACTGTGGAGAAAGTAAGTCACGTGGGCCCTTGAGGACCTGGACTGGGTTAGGAACAGTTGTACTTT
CAGAGGTGAGGTGTCGAGAAGGGAAAGTGAATGTGGTCTGGAGTGTGTCCTTGGCCTTGGCTCCACAGGGTGTGCTTTCCTCTGGGGCCG
TCAGGGAGCTCATCCCTTGTGTTCTGCCAGGGTGGGGTACGGGGTTTGACACTGAGGAGGGTAACCTGCTGGCTGGAGCGGCAGAGCAGT
GGCCTTGATTTGTCTTTTGGAAGATTTTAAAAACCAAAAAGCATAAACATTCTGGTCCTTCAGCAATGCTTTCTCTGAAGAAATACTTAA
CGGAAGGACTTCTCCAGTTCACCATTCTGCTGAGTTTGATTGGGGTACGGGTGGACGTGGATACTTACCTGACCTCACAGCTTCCCCCAC
TCCGGGAGATCATCCTGGGGCCCAGTTCTGCCTATACTCAGACCCAGTTCCACAACCTGAGGAATACCTTGGATGGCTATGGTATCCACC
CCAAGAGCATAGACCTGGACAATTACTTCACTGCCCGGCGGCTCCTCAGTCAGGTGAGGGCCCTGGACAGGTTCCAGGTGCCAACCACTG
AGGTAAATGCCTGGCTGGTTCACCGAGACCCAGAGGGGTCTGTCTCTGGCAGTCAGCCCAACTCAGGCCTCGCCCTCGAGAGTTCCAGTG
GCCTCCAAGATGTGACAGGCCCAGACAACGGGGTGCGAGAAAGCGAAACGGAGCAGGGATTCGGTGAAGATTTGGAGGATTTGGGGGCTG
TAGCCCCCCCAGTCAGTGGAGACTTAACCAAAGAGGACATAGATCTGATTGACATCCTTTGGCGACAGGATATTGATCTGGGGGCTGGGC
GTGAGGTTTTTGACTATAGTCACCGCCAGAAGGAGCAGGATGTGGAGAAGGAGCTGCGAGATGGAGGCGAGCAGGACACCTGGGCAGGCG
AGGGCGCGGAAGCTCTGGCACGGAACCTGCTAGTGGATGGAGAGACTGGGGAGAGCTTCCCTGCACAGTTTCCAGCAGACATTTCCAGCA
TAACAGAAGCAGTGCCTAGTGAGAGTGAGCCCCCTGCTCTTCAAAACAACCTCTTGTCTCCTCTTCTGACCGGGACAGAGTCACCATTTG
ATTTGGAACAGCAGTGGCAAGATCTCATGTCCATCATGGAAATGCAGGCATTTGAGGAGACTCATCTGACCTCCCTTGACCCAGTGAAAC
AGTTTGCTGCCTGGTTTGAGGAGGCTGTTCAGTGTCCTGACATAGGGGAAGCCAATGCCATGTGTCTGGCTACCTGCACCAGAGATGGAA
AACCCTCTGCTCGCATGTTGCTGCTGAAGGGCTTCGGGAAAGATGGCTTCCGCTTCTTCACTAACTTCGAGAGTCGAAAAGGAAAAGAGC
TGGTGCGTGTGGAAGGCCCTGTGAAGAAACTGCCTGAGGAGGAGGCTGAGTGCTACTTCCACTCCCGCCCCAAGAGCAGCCAGATTGGGG
CTGTGGTCAGCCACCAGAGTTCTGTGATCCCTGATCGGGAGTATCTGAGAAAGAAAAATGAGGAACTGGAACAGCTCTACCAGGATCAAG
AGGTGCCCAAGCCAAAATCCTGGGGTGGCTATGTCCTGTACCCTCAGGTGATGGAGTTCTGGCAAGGTCAAACCAACCGCCTGCATGACC
GGATAGTCTTTCGGCGGGGCCTACCCACAGGAGATTCCCCTTTGGGGCCCATGACCCACCGCGGGGAGGAAGACTGGCTCTATGAGAGAC
TTGCACCTTAACTCTGGGACCTGCTGGCCCAGAGTGGAGCTAGGGCTAGGTGTCAAGAGAGGGTGTGGGATTGGGACCCAGGCCCTTCTT
TCTAAACTCAACCCATTTCCCTCCCTACCCCTTATCTTCAGGACTCTTCAGAGCTAATCCTCTAAGTTCTCTGTACTCAGTTGGTTCTCA
GTTAGCTGGTCAAGTGGAGTGTAATGGTGGCGTAGAGAATCACAAATGGAAAATAATTCCATAATTATTTTTTTGACCTTGCCTATGATT
GATTAGGATAGCTCCCTCTAGGGGTAGCAGCCGGTGTGACTCCCTTTCTGGTGACAGACAGGGCCCCAGCAGCCCTGTCTGTTACCATGT

>In-frame_ENST00000357480_ENST00000544840_TCGA-EY-A2OQ-01A_NFE2L1_chr17_46134864_+_PNPO_chr17_46020672_length(amino acids)=491AA_start in transcript=605_stop in transcript=2080
MLSLKKYLTEGLLQFTILLSLIGVRVDVDTYLTSQLPPLREIILGPSSAYTQTQFHNLRNTLDGYGIHPKSIDLDNYFTARRLLSQVRAL
DRFQVPTTEVNAWLVHRDPEGSVSGSQPNSGLALESSSGLQDVTGPDNGVRESETEQGFGEDLEDLGAVAPPVSGDLTKEDIDLIDILWR
QDIDLGAGREVFDYSHRQKEQDVEKELRDGGEQDTWAGEGAEALARNLLVDGETGESFPAQFPADISSITEAVPSESEPPALQNNLLSPL
LTGTESPFDLEQQWQDLMSIMEMQAFEETHLTSLDPVKQFAAWFEEAVQCPDIGEANAMCLATCTRDGKPSARMLLLKGFGKDGFRFFTN
FESRKGKELVRVEGPVKKLPEEEAECYFHSRPKSSQIGAVVSHQSSVIPDREYLRKKNEELEQLYQDQEVPKPKSWGGYVLYPQVMEFWQ

--------------------------------------------------------------
>In-frame_ENST00000357480_ENST00000434554_TCGA-EY-A2OQ-01A_NFE2L1_chr17_46134864_+_PNPO_chr17_46020672_length(transcript)=2454nt_BP=1487nt
CCGAGCTCTAGGCCGGCCGGCGGTGGCGGCGGCGAGGCCGGGACTCGGGCTTAGGGCCTGCTGTGGAGGCAGCGGCGGACGCCGAGCTAA
GCAGTTTCTCTGGAAACCCCCCTGGTAAGTGTGGAGGAGGCGGGACACTCTGACCCAAGACGAAAGGCCTGTAGCTCCAGCCAAAGAAAA
TAAACCTTAGGAGGGAGAAGGAAAAAAAAAATCCATCAGCTGTTCCTGAGAACAGCCTGCATTGGAATCTACAGAGAGGACAACTAATGT
GAGTGAGGAAGTGACTGTATGTGGACTGTGGAGAAAGTAAGTCACGTGGGCCCTTGAGGACCTGGACTGGGTTAGGAACAGTTGTACTTT
CAGAGGTGAGGTGTCGAGAAGGGAAAGTGAATGTGGTCTGGAGTGTGTCCTTGGCCTTGGCTCCACAGGGTGTGCTTTCCTCTGGGGCCG
TCAGGGAGCTCATCCCTTGTGTTCTGCCAGGGTGGGGTACGGGGTTTGACACTGAGGAGGGTAACCTGCTGGCTGGAGCGGCAGAGCAGT
GGCCTTGATTTGTCTTTTGGAAGATTTTAAAAACCAAAAAGCATAAACATTCTGGTCCTTCAGCAATGCTTTCTCTGAAGAAATACTTAA
CGGAAGGACTTCTCCAGTTCACCATTCTGCTGAGTTTGATTGGGGTACGGGTGGACGTGGATACTTACCTGACCTCACAGCTTCCCCCAC
TCCGGGAGATCATCCTGGGGCCCAGTTCTGCCTATACTCAGACCCAGTTCCACAACCTGAGGAATACCTTGGATGGCTATGGTATCCACC
CCAAGAGCATAGACCTGGACAATTACTTCACTGCCCGGCGGCTCCTCAGTCAGGTGAGGGCCCTGGACAGGTTCCAGGTGCCAACCACTG
AGGTAAATGCCTGGCTGGTTCACCGAGACCCAGAGGGGTCTGTCTCTGGCAGTCAGCCCAACTCAGGCCTCGCCCTCGAGAGTTCCAGTG
GCCTCCAAGATGTGACAGGCCCAGACAACGGGGTGCGAGAAAGCGAAACGGAGCAGGGATTCGGTGAAGATTTGGAGGATTTGGGGGCTG
TAGCCCCCCCAGTCAGTGGAGACTTAACCAAAGAGGACATAGATCTGATTGACATCCTTTGGCGACAGGATATTGATCTGGGGGCTGGGC
GTGAGGTTTTTGACTATAGTCACCGCCAGAAGGAGCAGGATGTGGAGAAGGAGCTGCGAGATGGAGGCGAGCAGGACACCTGGGCAGGCG
AGGGCGCGGAAGCTCTGGCACGGAACCTGCTAGTGGATGGAGAGACTGGGGAGAGCTTCCCTGCACAGTTTCCAGCAGACATTTCCAGCA
TAACAGAAGCAGTGCCTAGTGAGAGTGAGCCCCCTGCTCTTCAAAACAACCTCTTGTCTCCTCTTCTGACCGGGACAGAGTCACCATTTG
ATTTGGAACAGCAGTGGCAAGATCTCATGTCCATCATGGAAATGCAGGCATTTGAGGAGACTCATCTGACCTCCCTTGACCCAGTGAAAC
AGTTTGCTGCCTGGTTTGAGGAGGCTGTTCAGTGTCCTGACATAGGGGAAGCCAATGCCATGTGTCTGGCTACCTGCACCAGAGATGGAA
AACCCTCTGCTCGCATGTTGCTGCTGAAGGGCTTCGGGAAAGATGGCTTCCGCTTCTTCACTAACTTCGAGAGTCGAAAAGGAAAAGAGC
TGGACTCTAATCCCTTTGCTTCCCTTGTCTTCTACTGGGAGCCACTTAACCGTCAGTATCTGAGAAAGAAAAATGAGGAACTGGAACAGC
TCTACCAGGATCAAGAGGTGCCCAAGCCAAAATCCTGGGGTGGCTATGTCCTGTACCCTCAGGTGATGGAGTTCTGGCAAGGTCAAACCA
ACCGCCTGCATGACCGGATAGTCTTTCGGCGGGGCCTACCCACAGGAGATTCCCCTTTGGGGCCCATGACCCACCGCGGGGAGGAAGACT
GGCTCTATGAGAGACTTGCACCTTAACTCTGGGACCTGCTGGCCCAGAGTGGAGCTAGGGCTAGGTGTCAAGAGAGGGTGTGGGATTGGG
ACCCAGGCCCTTCTTTCTAAACTCAACCCATTTCCCTCCCTACCCCTTATCTTCAGGACTCTTCAGAGCTAATCCTCTAAGTTCTCTGTA
CTCAGTTGGTTCTCAGTTAGCTGGTCAAGTGGAGTGTAATGGTGGCGTAGAGAATCACAAATGGAAAATAATTCCATAATTATTTTTTTG
ACCTTGCCTATGATTGATTAGGATAGCTCCCTCTAGGGGTAGCAGCCGGTGTGACTCCCTTTCTGGTGACAGACAGGGCCCCAGCAGCCC
TGTCTGTTACCATGTGAGTCATACTGGCCAAAGCTTAGTCCTAGCATATGCACCTGAGCCAACCTGGCCAATCAGATTGTTTTGTCAATA

>In-frame_ENST00000357480_ENST00000434554_TCGA-EY-A2OQ-01A_NFE2L1_chr17_46134864_+_PNPO_chr17_46020672_length(amino acids)=466AA_start in transcript=605_stop in transcript=2005
MLSLKKYLTEGLLQFTILLSLIGVRVDVDTYLTSQLPPLREIILGPSSAYTQTQFHNLRNTLDGYGIHPKSIDLDNYFTARRLLSQVRAL
DRFQVPTTEVNAWLVHRDPEGSVSGSQPNSGLALESSSGLQDVTGPDNGVRESETEQGFGEDLEDLGAVAPPVSGDLTKEDIDLIDILWR
QDIDLGAGREVFDYSHRQKEQDVEKELRDGGEQDTWAGEGAEALARNLLVDGETGESFPAQFPADISSITEAVPSESEPPALQNNLLSPL
LTGTESPFDLEQQWQDLMSIMEMQAFEETHLTSLDPVKQFAAWFEEAVQCPDIGEANAMCLATCTRDGKPSARMLLLKGFGKDGFRFFTN
FESRKGKELDSNPFASLVFYWEPLNRQYLRKKNEELEQLYQDQEVPKPKSWGGYVLYPQVMEFWQGQTNRLHDRIVFRRGLPTGDSPLGP

--------------------------------------------------------------
>In-frame_ENST00000357480_ENST00000225573_TCGA-EY-A2OQ-01A_NFE2L1_chr17_46134864_+_PNPO_chr17_46020672_length(transcript)=3641nt_BP=1487nt
CCGAGCTCTAGGCCGGCCGGCGGTGGCGGCGGCGAGGCCGGGACTCGGGCTTAGGGCCTGCTGTGGAGGCAGCGGCGGACGCCGAGCTAA
GCAGTTTCTCTGGAAACCCCCCTGGTAAGTGTGGAGGAGGCGGGACACTCTGACCCAAGACGAAAGGCCTGTAGCTCCAGCCAAAGAAAA
TAAACCTTAGGAGGGAGAAGGAAAAAAAAAATCCATCAGCTGTTCCTGAGAACAGCCTGCATTGGAATCTACAGAGAGGACAACTAATGT
GAGTGAGGAAGTGACTGTATGTGGACTGTGGAGAAAGTAAGTCACGTGGGCCCTTGAGGACCTGGACTGGGTTAGGAACAGTTGTACTTT
CAGAGGTGAGGTGTCGAGAAGGGAAAGTGAATGTGGTCTGGAGTGTGTCCTTGGCCTTGGCTCCACAGGGTGTGCTTTCCTCTGGGGCCG
TCAGGGAGCTCATCCCTTGTGTTCTGCCAGGGTGGGGTACGGGGTTTGACACTGAGGAGGGTAACCTGCTGGCTGGAGCGGCAGAGCAGT
GGCCTTGATTTGTCTTTTGGAAGATTTTAAAAACCAAAAAGCATAAACATTCTGGTCCTTCAGCAATGCTTTCTCTGAAGAAATACTTAA
CGGAAGGACTTCTCCAGTTCACCATTCTGCTGAGTTTGATTGGGGTACGGGTGGACGTGGATACTTACCTGACCTCACAGCTTCCCCCAC
TCCGGGAGATCATCCTGGGGCCCAGTTCTGCCTATACTCAGACCCAGTTCCACAACCTGAGGAATACCTTGGATGGCTATGGTATCCACC
CCAAGAGCATAGACCTGGACAATTACTTCACTGCCCGGCGGCTCCTCAGTCAGGTGAGGGCCCTGGACAGGTTCCAGGTGCCAACCACTG
AGGTAAATGCCTGGCTGGTTCACCGAGACCCAGAGGGGTCTGTCTCTGGCAGTCAGCCCAACTCAGGCCTCGCCCTCGAGAGTTCCAGTG
GCCTCCAAGATGTGACAGGCCCAGACAACGGGGTGCGAGAAAGCGAAACGGAGCAGGGATTCGGTGAAGATTTGGAGGATTTGGGGGCTG
TAGCCCCCCCAGTCAGTGGAGACTTAACCAAAGAGGACATAGATCTGATTGACATCCTTTGGCGACAGGATATTGATCTGGGGGCTGGGC
GTGAGGTTTTTGACTATAGTCACCGCCAGAAGGAGCAGGATGTGGAGAAGGAGCTGCGAGATGGAGGCGAGCAGGACACCTGGGCAGGCG
AGGGCGCGGAAGCTCTGGCACGGAACCTGCTAGTGGATGGAGAGACTGGGGAGAGCTTCCCTGCACAGTTTCCAGCAGACATTTCCAGCA
TAACAGAAGCAGTGCCTAGTGAGAGTGAGCCCCCTGCTCTTCAAAACAACCTCTTGTCTCCTCTTCTGACCGGGACAGAGTCACCATTTG
ATTTGGAACAGCAGTGGCAAGATCTCATGTCCATCATGGAAATGCAGGCATTTGAGGAGACTCATCTGACCTCCCTTGACCCAGTGAAAC
AGTTTGCTGCCTGGTTTGAGGAGGCTGTTCAGTGTCCTGACATAGGGGAAGCCAATGCCATGTGTCTGGCTACCTGCACCAGAGATGGAA
AACCCTCTGCTCGCATGTTGCTGCTGAAGGGCTTCGGGAAAGATGGCTTCCGCTTCTTCACTAACTTCGAGAGTCGAAAAGGAAAAGAGC
TGGACTCTAATCCCTTTGCTTCCCTTGTCTTCTACTGGGAGCCACTTAACCGTCAGGTGCGTGTGGAAGGCCCTGTGAAGAAACTGCCTG
AGGAGGAGGCTGAGTGCTACTTCCACTCCCGCCCCAAGAGCAGCCAGATTGGGGCTGTGGTCAGCCACCAGAGTTCTGTGATCCCTGATC
GGGAGTATCTGAGAAAGAAAAATGAGGAACTGGAACAGCTCTACCAGGATCAAGAGGTGCCCAAGCCAAAATCCTGGGGTGGCTATGTCC
TGTACCCTCAGGTGATGGAGTTCTGGCAAGGTCAAACCAACCGCCTGCATGACCGGATAGTCTTTCGGCGGGGCCTACCCACAGGAGATT
CCCCTTTGGGGCCCATGACCCACCGCGGGGAGGAAGACTGGCTCTATGAGAGACTTGCACCTTAACTCTGGGACCTGCTGGCCCAGAGTG
GAGCTAGGGCTAGGTGTCAAGAGAGGGTGTGGGATTGGGACCCAGGCCCTTCTTTCTAAACTCAACCCATTTCCCTCCCTACCCCTTATC
TTCAGGACTCTTCAGAGCTAATCCTCTAAGTTCTCTGTACTCAGTTGGTTCTCAGTTAGCTGGTCAAGTGGAGTGTAATGGTGGCGTAGA
GAATCACAAATGGAAAATAATTCCATAATTATTTTTTTGACCTTGCCTATGATTGATTAGGATAGCTCCCTCTAGGGGTAGCAGCCGGTG
TGACTCCCTTTCTGGTGACAGACAGGGCCCCAGCAGCCCTGTCTGTTACCATGTGAGTCATACTGGCCAAAGCTTAGTCCTAGCATATGC
ACCTGAGCCAACCTGGCCAATCAGATTGTTTTGTCAATAATTTGAAATTTGAACTGGAGAGATCCAGAACCTTGGGAGTCATTAAAGCCA
AGTCATTCATAGCAGCCAGGAAACAATAGGAACCAAAAGCCTCTGCCTGCTGCTATTGCAATTCCCAGGATCTCTCCTTCCCTGGATCCC
TCCCTCCCAGGTCTGGGCTGTGCAGTTCCTCCCCCTGCCTTAAAACACCCCACTATCTCTGTAAAGTCTCTCTCTCTCTTTTTTTTTTTT
TTACTTAATCTAGCTAGAATCTATTTCTGTTGATTACAACTTAACTAACTCATTTACGGATAGGACTTTTTTTTTTCTTTTTTTCTTTTT
TCTTTTCTTTTTTTTTTTTGAGATGGAGTCTCACTCTGTCACCCAGGCTGGAGTGCAGTGGTGTGATCTTGGCTCACTGCAACCTCTGCC
TCCCAGGTTCAAGCAATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGACTACAGGCACACGCCACCACACCCAACTAATTTTTGTATTTT
TAGTAGAGATGGGGTTTCACCATGTTGGCCAGGATTGTCTCCATCTCTTGACCTTGTGATCCACCCACCTCAGCCTCCCAAAGTGCTGGG
ATTACAGGCATGAGCCACCACACCCAGCGAGACGGGGTTTCATTATGTTGGCCAGGCTGGTCTCCAACTCCTGACCTAAAGTGATCTGCC
CGCCTTGGCCTCCCAAAGTGCTGGGATTACAGACATGAGCCACCACGCTTGGCCGGGATAGTATATTTTTATAGCACTTCCCCTACTGAT
TGCTGCCTTCTCTGTGGCTACAAGGGACCCACAGAATTACAGGGAAGTTACAGGGAAGCAGGTTTCATCTCAATATTGGGAGAGATTTCA
AACAATCACACCTGCCTGAGAAGGAGTGGGCTGTCACTAGGAATTTTTATTCCCAGTCCGTCAGGAATTTTGTAGAAGGGCTTCATGTGC
TGGTACCAATAGGACAGGAAGATTTTAATCAGCTTTACTATCTATGTTTTTTTATGGAAACTGTGTGTATGTATACATACATTTTCCAAA

>In-frame_ENST00000357480_ENST00000225573_TCGA-EY-A2OQ-01A_NFE2L1_chr17_46134864_+_PNPO_chr17_46020672_length(amino acids)=509AA_start in transcript=605_stop in transcript=2134
MLSLKKYLTEGLLQFTILLSLIGVRVDVDTYLTSQLPPLREIILGPSSAYTQTQFHNLRNTLDGYGIHPKSIDLDNYFTARRLLSQVRAL
DRFQVPTTEVNAWLVHRDPEGSVSGSQPNSGLALESSSGLQDVTGPDNGVRESETEQGFGEDLEDLGAVAPPVSGDLTKEDIDLIDILWR
QDIDLGAGREVFDYSHRQKEQDVEKELRDGGEQDTWAGEGAEALARNLLVDGETGESFPAQFPADISSITEAVPSESEPPALQNNLLSPL
LTGTESPFDLEQQWQDLMSIMEMQAFEETHLTSLDPVKQFAAWFEEAVQCPDIGEANAMCLATCTRDGKPSARMLLLKGFGKDGFRFFTN
FESRKGKELDSNPFASLVFYWEPLNRQVRVEGPVKKLPEEEAECYFHSRPKSSQIGAVVSHQSSVIPDREYLRKKNEELEQLYQDQEVPK

--------------------------------------------------------------
>In-frame_ENST00000361665_ENST00000544840_TCGA-EY-A2OQ-01A_NFE2L1_chr17_46134864_+_PNPO_chr17_46020672_length(transcript)=2496nt_BP=1543nt
AGGGAAGTAGCACTTGTTCGCTGGCCGCCCCTGGAGGCTAGAAGCTCCGGCGCCGAGAGTGGGCATGGCGACTTGGTCTCAGCCGGACTC
GGGTTTCTCTGGAAACCCCCCTGGTAAGTGTGGAGGAGGCGGGACACTCTGACCCAAGACGAAAGGCCTGTAGCTCCAGCCAAAGAAAAT
AAACCTTAGGAGGGAGAAGGAAAAAAAAAATCCATCAGCTGTTCCTGAGAACAGCCTGCATTGGAATCTACAGAGAGGACAACTAATGTG
AGTGAGGAAGTGACTGTATGTGGACTGTGGAGAAAGTAAGTCACGTGGGCCCTTGAGGACCTGGACTGGGTTAGGAACAGTTGTACTTTC
AGAGGTGAGGTGTCGAGAAGGGAAAGTGAATGTGGTCTGGAGTGTGTCCTTGGCCTTGGCTCCACAGGGTGTGCTTTCCTCTGGGGCCGT
CAGGGAGCTCATCCCTTGTGTTCTGCCAGGGTGGGGTACGGGGTTTGACACTGAGGAGGGTAACCTGCTGGCTGGAGCGGCAGAGCAGTG
GCCTTGATTTGTCTTTTGGAAGATTTTAAAAACCAAAAAGCATAAACATTCTGGTCCTTCAGCAATGCTTTCTCTGAAGAAATACTTAAC
GGAAGGACTTCTCCAGTTCACCATTCTGCTGAGTTTGATTGGGGTACGGGTGGACGTGGATACTTACCTGACCTCACAGCTTCCCCCACT
CCGGGAGATCATCCTGGGGCCCAGTTCTGCCTATACTCAGACCCAGTTCCACAACCTGAGGAATACCTTGGATGGCTATGGTATCCACCC
CAAGAGCATAGACCTGGACAATTACTTCACTGCCCGGCGGCTCCTCAGTCAGGTGAGGGCCCTGGACAGGTTCCAGGTGCCAACCACTGA
GGTAAATGCCTGGCTGGTTCACCGAGACCCAGAGGGGTCTGTCTCTGGCAGTCAGCCCAACTCAGGCCTCGCCCTCGAGAGTTCCAGTGG
CCTCCAAGATGTGACAGGCCCAGACAACGGGGTGCGAGAAAGCGAAACGGAGCAGGGATTCGGTGAAGATTTGGAGGATTTGGGGGCTGT
AGCCCCCCCAGTCAGTGGAGACTTAACCAAAGAGGATATTGATCTGGGGGCTGGGCGTGAGGTTTTTGACTATAGTCACCGCCAGAAGGA
GCAGGATGTGGAGAAGGAGCTGCGAGATGGAGGCGAGCAGGACACCTGGGCAGGCGAGGGCGCGGAAGCTCTGGCACGGAACCTGCTAGT
GGATGGAGAGACTGGGGAGAGCTTCCCTGCACAGGTGCCTAGTGGGGAGGACCAGACGGCCCTGTCCCTGGAAGAGTGCCTTAGGCTGCT
GGAAGCCACCTGCCCCTTTGGGGAGAATGCTGAGTTTCCAGCAGACATTTCCAGCATAACAGAAGCAGTGCCTAGTGAGAGTGAGCCCCC
TGCTCTTCAAAACAACCTCTTGTCTCCTCTTCTGACCGGGACAGAGTCACCATTTGATTTGGAACAGCAGTGGCAAGATCTCATGTCCAT
CATGGAAATGCAGGCATTTGAGGAGACTCATCTGACCTCCCTTGACCCAGTGAAACAGTTTGCTGCCTGGTTTGAGGAGGCTGTTCAGTG
TCCTGACATAGGGGAAGCCAATGCCATGTGTCTGGCTACCTGCACCAGAGATGGAAAACCCTCTGCTCGCATGTTGCTGCTGAAGGGCTT
CGGGAAAGATGGCTTCCGCTTCTTCACTAACTTCGAGAGTCGAAAAGGAAAAGAGCTGGTGCGTGTGGAAGGCCCTGTGAAGAAACTGCC
TGAGGAGGAGGCTGAGTGCTACTTCCACTCCCGCCCCAAGAGCAGCCAGATTGGGGCTGTGGTCAGCCACCAGAGTTCTGTGATCCCTGA
TCGGGAGTATCTGAGAAAGAAAAATGAGGAACTGGAACAGCTCTACCAGGATCAAGAGGTGCCCAAGCCAAAATCCTGGGGTGGCTATGT
CCTGTACCCTCAGGTGATGGAGTTCTGGCAAGGTCAAACCAACCGCCTGCATGACCGGATAGTCTTTCGGCGGGGCCTACCCACAGGAGA
TTCCCCTTTGGGGCCCATGACCCACCGCGGGGAGGAAGACTGGCTCTATGAGAGACTTGCACCTTAACTCTGGGACCTGCTGGCCCAGAG
TGGAGCTAGGGCTAGGTGTCAAGAGAGGGTGTGGGATTGGGACCCAGGCCCTTCTTTCTAAACTCAACCCATTTCCCTCCCTACCCCTTA
TCTTCAGGACTCTTCAGAGCTAATCCTCTAAGTTCTCTGTACTCAGTTGGTTCTCAGTTAGCTGGTCAAGTGGAGTGTAATGGTGGCGTA
GAGAATCACAAATGGAAAATAATTCCATAATTATTTTTTTGACCTTGCCTATGATTGATTAGGATAGCTCCCTCTAGGGGTAGCAGCCGG

>In-frame_ENST00000361665_ENST00000544840_TCGA-EY-A2OQ-01A_NFE2L1_chr17_46134864_+_PNPO_chr17_46020672_length(amino acids)=510AA_start in transcript=604_stop in transcript=2136
MLSLKKYLTEGLLQFTILLSLIGVRVDVDTYLTSQLPPLREIILGPSSAYTQTQFHNLRNTLDGYGIHPKSIDLDNYFTARRLLSQVRAL
DRFQVPTTEVNAWLVHRDPEGSVSGSQPNSGLALESSSGLQDVTGPDNGVRESETEQGFGEDLEDLGAVAPPVSGDLTKEDIDLGAGREV
FDYSHRQKEQDVEKELRDGGEQDTWAGEGAEALARNLLVDGETGESFPAQVPSGEDQTALSLEECLRLLEATCPFGENAEFPADISSITE
AVPSESEPPALQNNLLSPLLTGTESPFDLEQQWQDLMSIMEMQAFEETHLTSLDPVKQFAAWFEEAVQCPDIGEANAMCLATCTRDGKPS
ARMLLLKGFGKDGFRFFTNFESRKGKELVRVEGPVKKLPEEEAECYFHSRPKSSQIGAVVSHQSSVIPDREYLRKKNEELEQLYQDQEVP

--------------------------------------------------------------
>In-frame_ENST00000361665_ENST00000434554_TCGA-EY-A2OQ-01A_NFE2L1_chr17_46134864_+_PNPO_chr17_46020672_length(transcript)=2510nt_BP=1543nt
AGGGAAGTAGCACTTGTTCGCTGGCCGCCCCTGGAGGCTAGAAGCTCCGGCGCCGAGAGTGGGCATGGCGACTTGGTCTCAGCCGGACTC
GGGTTTCTCTGGAAACCCCCCTGGTAAGTGTGGAGGAGGCGGGACACTCTGACCCAAGACGAAAGGCCTGTAGCTCCAGCCAAAGAAAAT
AAACCTTAGGAGGGAGAAGGAAAAAAAAAATCCATCAGCTGTTCCTGAGAACAGCCTGCATTGGAATCTACAGAGAGGACAACTAATGTG
AGTGAGGAAGTGACTGTATGTGGACTGTGGAGAAAGTAAGTCACGTGGGCCCTTGAGGACCTGGACTGGGTTAGGAACAGTTGTACTTTC
AGAGGTGAGGTGTCGAGAAGGGAAAGTGAATGTGGTCTGGAGTGTGTCCTTGGCCTTGGCTCCACAGGGTGTGCTTTCCTCTGGGGCCGT
CAGGGAGCTCATCCCTTGTGTTCTGCCAGGGTGGGGTACGGGGTTTGACACTGAGGAGGGTAACCTGCTGGCTGGAGCGGCAGAGCAGTG
GCCTTGATTTGTCTTTTGGAAGATTTTAAAAACCAAAAAGCATAAACATTCTGGTCCTTCAGCAATGCTTTCTCTGAAGAAATACTTAAC
GGAAGGACTTCTCCAGTTCACCATTCTGCTGAGTTTGATTGGGGTACGGGTGGACGTGGATACTTACCTGACCTCACAGCTTCCCCCACT
CCGGGAGATCATCCTGGGGCCCAGTTCTGCCTATACTCAGACCCAGTTCCACAACCTGAGGAATACCTTGGATGGCTATGGTATCCACCC
CAAGAGCATAGACCTGGACAATTACTTCACTGCCCGGCGGCTCCTCAGTCAGGTGAGGGCCCTGGACAGGTTCCAGGTGCCAACCACTGA
GGTAAATGCCTGGCTGGTTCACCGAGACCCAGAGGGGTCTGTCTCTGGCAGTCAGCCCAACTCAGGCCTCGCCCTCGAGAGTTCCAGTGG
CCTCCAAGATGTGACAGGCCCAGACAACGGGGTGCGAGAAAGCGAAACGGAGCAGGGATTCGGTGAAGATTTGGAGGATTTGGGGGCTGT
AGCCCCCCCAGTCAGTGGAGACTTAACCAAAGAGGATATTGATCTGGGGGCTGGGCGTGAGGTTTTTGACTATAGTCACCGCCAGAAGGA
GCAGGATGTGGAGAAGGAGCTGCGAGATGGAGGCGAGCAGGACACCTGGGCAGGCGAGGGCGCGGAAGCTCTGGCACGGAACCTGCTAGT
GGATGGAGAGACTGGGGAGAGCTTCCCTGCACAGGTGCCTAGTGGGGAGGACCAGACGGCCCTGTCCCTGGAAGAGTGCCTTAGGCTGCT
GGAAGCCACCTGCCCCTTTGGGGAGAATGCTGAGTTTCCAGCAGACATTTCCAGCATAACAGAAGCAGTGCCTAGTGAGAGTGAGCCCCC
TGCTCTTCAAAACAACCTCTTGTCTCCTCTTCTGACCGGGACAGAGTCACCATTTGATTTGGAACAGCAGTGGCAAGATCTCATGTCCAT
CATGGAAATGCAGGCATTTGAGGAGACTCATCTGACCTCCCTTGACCCAGTGAAACAGTTTGCTGCCTGGTTTGAGGAGGCTGTTCAGTG
TCCTGACATAGGGGAAGCCAATGCCATGTGTCTGGCTACCTGCACCAGAGATGGAAAACCCTCTGCTCGCATGTTGCTGCTGAAGGGCTT
CGGGAAAGATGGCTTCCGCTTCTTCACTAACTTCGAGAGTCGAAAAGGAAAAGAGCTGGACTCTAATCCCTTTGCTTCCCTTGTCTTCTA
CTGGGAGCCACTTAACCGTCAGTATCTGAGAAAGAAAAATGAGGAACTGGAACAGCTCTACCAGGATCAAGAGGTGCCCAAGCCAAAATC
CTGGGGTGGCTATGTCCTGTACCCTCAGGTGATGGAGTTCTGGCAAGGTCAAACCAACCGCCTGCATGACCGGATAGTCTTTCGGCGGGG
CCTACCCACAGGAGATTCCCCTTTGGGGCCCATGACCCACCGCGGGGAGGAAGACTGGCTCTATGAGAGACTTGCACCTTAACTCTGGGA
CCTGCTGGCCCAGAGTGGAGCTAGGGCTAGGTGTCAAGAGAGGGTGTGGGATTGGGACCCAGGCCCTTCTTTCTAAACTCAACCCATTTC
CCTCCCTACCCCTTATCTTCAGGACTCTTCAGAGCTAATCCTCTAAGTTCTCTGTACTCAGTTGGTTCTCAGTTAGCTGGTCAAGTGGAG
TGTAATGGTGGCGTAGAGAATCACAAATGGAAAATAATTCCATAATTATTTTTTTGACCTTGCCTATGATTGATTAGGATAGCTCCCTCT
AGGGGTAGCAGCCGGTGTGACTCCCTTTCTGGTGACAGACAGGGCCCCAGCAGCCCTGTCTGTTACCATGTGAGTCATACTGGCCAAAGC

>In-frame_ENST00000361665_ENST00000434554_TCGA-EY-A2OQ-01A_NFE2L1_chr17_46134864_+_PNPO_chr17_46020672_length(amino acids)=485AA_start in transcript=604_stop in transcript=2061
MLSLKKYLTEGLLQFTILLSLIGVRVDVDTYLTSQLPPLREIILGPSSAYTQTQFHNLRNTLDGYGIHPKSIDLDNYFTARRLLSQVRAL
DRFQVPTTEVNAWLVHRDPEGSVSGSQPNSGLALESSSGLQDVTGPDNGVRESETEQGFGEDLEDLGAVAPPVSGDLTKEDIDLGAGREV
FDYSHRQKEQDVEKELRDGGEQDTWAGEGAEALARNLLVDGETGESFPAQVPSGEDQTALSLEECLRLLEATCPFGENAEFPADISSITE
AVPSESEPPALQNNLLSPLLTGTESPFDLEQQWQDLMSIMEMQAFEETHLTSLDPVKQFAAWFEEAVQCPDIGEANAMCLATCTRDGKPS
ARMLLLKGFGKDGFRFFTNFESRKGKELDSNPFASLVFYWEPLNRQYLRKKNEELEQLYQDQEVPKPKSWGGYVLYPQVMEFWQGQTNRL

--------------------------------------------------------------
>In-frame_ENST00000361665_ENST00000225573_TCGA-EY-A2OQ-01A_NFE2L1_chr17_46134864_+_PNPO_chr17_46020672_length(transcript)=3697nt_BP=1543nt
AGGGAAGTAGCACTTGTTCGCTGGCCGCCCCTGGAGGCTAGAAGCTCCGGCGCCGAGAGTGGGCATGGCGACTTGGTCTCAGCCGGACTC
GGGTTTCTCTGGAAACCCCCCTGGTAAGTGTGGAGGAGGCGGGACACTCTGACCCAAGACGAAAGGCCTGTAGCTCCAGCCAAAGAAAAT
AAACCTTAGGAGGGAGAAGGAAAAAAAAAATCCATCAGCTGTTCCTGAGAACAGCCTGCATTGGAATCTACAGAGAGGACAACTAATGTG
AGTGAGGAAGTGACTGTATGTGGACTGTGGAGAAAGTAAGTCACGTGGGCCCTTGAGGACCTGGACTGGGTTAGGAACAGTTGTACTTTC
AGAGGTGAGGTGTCGAGAAGGGAAAGTGAATGTGGTCTGGAGTGTGTCCTTGGCCTTGGCTCCACAGGGTGTGCTTTCCTCTGGGGCCGT
CAGGGAGCTCATCCCTTGTGTTCTGCCAGGGTGGGGTACGGGGTTTGACACTGAGGAGGGTAACCTGCTGGCTGGAGCGGCAGAGCAGTG
GCCTTGATTTGTCTTTTGGAAGATTTTAAAAACCAAAAAGCATAAACATTCTGGTCCTTCAGCAATGCTTTCTCTGAAGAAATACTTAAC
GGAAGGACTTCTCCAGTTCACCATTCTGCTGAGTTTGATTGGGGTACGGGTGGACGTGGATACTTACCTGACCTCACAGCTTCCCCCACT
CCGGGAGATCATCCTGGGGCCCAGTTCTGCCTATACTCAGACCCAGTTCCACAACCTGAGGAATACCTTGGATGGCTATGGTATCCACCC
CAAGAGCATAGACCTGGACAATTACTTCACTGCCCGGCGGCTCCTCAGTCAGGTGAGGGCCCTGGACAGGTTCCAGGTGCCAACCACTGA
GGTAAATGCCTGGCTGGTTCACCGAGACCCAGAGGGGTCTGTCTCTGGCAGTCAGCCCAACTCAGGCCTCGCCCTCGAGAGTTCCAGTGG
CCTCCAAGATGTGACAGGCCCAGACAACGGGGTGCGAGAAAGCGAAACGGAGCAGGGATTCGGTGAAGATTTGGAGGATTTGGGGGCTGT
AGCCCCCCCAGTCAGTGGAGACTTAACCAAAGAGGATATTGATCTGGGGGCTGGGCGTGAGGTTTTTGACTATAGTCACCGCCAGAAGGA
GCAGGATGTGGAGAAGGAGCTGCGAGATGGAGGCGAGCAGGACACCTGGGCAGGCGAGGGCGCGGAAGCTCTGGCACGGAACCTGCTAGT
GGATGGAGAGACTGGGGAGAGCTTCCCTGCACAGGTGCCTAGTGGGGAGGACCAGACGGCCCTGTCCCTGGAAGAGTGCCTTAGGCTGCT
GGAAGCCACCTGCCCCTTTGGGGAGAATGCTGAGTTTCCAGCAGACATTTCCAGCATAACAGAAGCAGTGCCTAGTGAGAGTGAGCCCCC
TGCTCTTCAAAACAACCTCTTGTCTCCTCTTCTGACCGGGACAGAGTCACCATTTGATTTGGAACAGCAGTGGCAAGATCTCATGTCCAT
CATGGAAATGCAGGCATTTGAGGAGACTCATCTGACCTCCCTTGACCCAGTGAAACAGTTTGCTGCCTGGTTTGAGGAGGCTGTTCAGTG
TCCTGACATAGGGGAAGCCAATGCCATGTGTCTGGCTACCTGCACCAGAGATGGAAAACCCTCTGCTCGCATGTTGCTGCTGAAGGGCTT
CGGGAAAGATGGCTTCCGCTTCTTCACTAACTTCGAGAGTCGAAAAGGAAAAGAGCTGGACTCTAATCCCTTTGCTTCCCTTGTCTTCTA
CTGGGAGCCACTTAACCGTCAGGTGCGTGTGGAAGGCCCTGTGAAGAAACTGCCTGAGGAGGAGGCTGAGTGCTACTTCCACTCCCGCCC
CAAGAGCAGCCAGATTGGGGCTGTGGTCAGCCACCAGAGTTCTGTGATCCCTGATCGGGAGTATCTGAGAAAGAAAAATGAGGAACTGGA
ACAGCTCTACCAGGATCAAGAGGTGCCCAAGCCAAAATCCTGGGGTGGCTATGTCCTGTACCCTCAGGTGATGGAGTTCTGGCAAGGTCA
AACCAACCGCCTGCATGACCGGATAGTCTTTCGGCGGGGCCTACCCACAGGAGATTCCCCTTTGGGGCCCATGACCCACCGCGGGGAGGA
AGACTGGCTCTATGAGAGACTTGCACCTTAACTCTGGGACCTGCTGGCCCAGAGTGGAGCTAGGGCTAGGTGTCAAGAGAGGGTGTGGGA
TTGGGACCCAGGCCCTTCTTTCTAAACTCAACCCATTTCCCTCCCTACCCCTTATCTTCAGGACTCTTCAGAGCTAATCCTCTAAGTTCT
CTGTACTCAGTTGGTTCTCAGTTAGCTGGTCAAGTGGAGTGTAATGGTGGCGTAGAGAATCACAAATGGAAAATAATTCCATAATTATTT
TTTTGACCTTGCCTATGATTGATTAGGATAGCTCCCTCTAGGGGTAGCAGCCGGTGTGACTCCCTTTCTGGTGACAGACAGGGCCCCAGC
AGCCCTGTCTGTTACCATGTGAGTCATACTGGCCAAAGCTTAGTCCTAGCATATGCACCTGAGCCAACCTGGCCAATCAGATTGTTTTGT
CAATAATTTGAAATTTGAACTGGAGAGATCCAGAACCTTGGGAGTCATTAAAGCCAAGTCATTCATAGCAGCCAGGAAACAATAGGAACC
AAAAGCCTCTGCCTGCTGCTATTGCAATTCCCAGGATCTCTCCTTCCCTGGATCCCTCCCTCCCAGGTCTGGGCTGTGCAGTTCCTCCCC
CTGCCTTAAAACACCCCACTATCTCTGTAAAGTCTCTCTCTCTCTTTTTTTTTTTTTTACTTAATCTAGCTAGAATCTATTTCTGTTGAT
TACAACTTAACTAACTCATTTACGGATAGGACTTTTTTTTTTCTTTTTTTCTTTTTTCTTTTCTTTTTTTTTTTTGAGATGGAGTCTCAC
TCTGTCACCCAGGCTGGAGTGCAGTGGTGTGATCTTGGCTCACTGCAACCTCTGCCTCCCAGGTTCAAGCAATTCTCCTGCCTCAGCCTC
CCAAGTAGCTGGGACTACAGGCACACGCCACCACACCCAACTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTGGCCAGGA
TTGTCTCCATCTCTTGACCTTGTGATCCACCCACCTCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCACACCCAGCGAGACG
GGGTTTCATTATGTTGGCCAGGCTGGTCTCCAACTCCTGACCTAAAGTGATCTGCCCGCCTTGGCCTCCCAAAGTGCTGGGATTACAGAC
ATGAGCCACCACGCTTGGCCGGGATAGTATATTTTTATAGCACTTCCCCTACTGATTGCTGCCTTCTCTGTGGCTACAAGGGACCCACAG
AATTACAGGGAAGTTACAGGGAAGCAGGTTTCATCTCAATATTGGGAGAGATTTCAAACAATCACACCTGCCTGAGAAGGAGTGGGCTGT
CACTAGGAATTTTTATTCCCAGTCCGTCAGGAATTTTGTAGAAGGGCTTCATGTGCTGGTACCAATAGGACAGGAAGATTTTAATCAGCT
TTACTATCTATGTTTTTTTATGGAAACTGTGTGTATGTATACATACATTTTCCAAAAAGAAAAATTAAATGATTATAGAGATTATGTTTT

>In-frame_ENST00000361665_ENST00000225573_TCGA-EY-A2OQ-01A_NFE2L1_chr17_46134864_+_PNPO_chr17_46020672_length(amino acids)=528AA_start in transcript=604_stop in transcript=2190
MLSLKKYLTEGLLQFTILLSLIGVRVDVDTYLTSQLPPLREIILGPSSAYTQTQFHNLRNTLDGYGIHPKSIDLDNYFTARRLLSQVRAL
DRFQVPTTEVNAWLVHRDPEGSVSGSQPNSGLALESSSGLQDVTGPDNGVRESETEQGFGEDLEDLGAVAPPVSGDLTKEDIDLGAGREV
FDYSHRQKEQDVEKELRDGGEQDTWAGEGAEALARNLLVDGETGESFPAQVPSGEDQTALSLEECLRLLEATCPFGENAEFPADISSITE
AVPSESEPPALQNNLLSPLLTGTESPFDLEQQWQDLMSIMEMQAFEETHLTSLDPVKQFAAWFEEAVQCPDIGEANAMCLATCTRDGKPS
ARMLLLKGFGKDGFRFFTNFESRKGKELDSNPFASLVFYWEPLNRQVRVEGPVKKLPEEEAECYFHSRPKSSQIGAVVSHQSSVIPDREY

--------------------------------------------------------------
>In-frame_ENST00000582155_ENST00000544840_TCGA-EY-A2OQ-01A_NFE2L1_chr17_46134864_+_PNPO_chr17_46020672_length(transcript)=1412nt_BP=459nt
AGGATAGGCCCAGGAGGGAGCTTGCTTTCCTCTGCAGCTTGAGCACGGAGCATGGGGTGGGAGTCCCATCTCACTGCAGCCTCTGCGGAC
ATAGATCTGATTGACATCCTTTGGCGACAGGATATTGATCTGGGGGCTGGGCGTGAGGTTTTTGACTATAGTCACCGCCAGAAGGAGCAG
GATGTGGAGAAGGAGCTGCGAGATGGAGGCGAGCAGGACACCTGGGCAGGCGAGGGCGCGGAAGCTCTGGCACGGAACCTGCTAGTGGAT
GGAGAGACTGGGGAGAGCTTCCCTGCACAGTTTCCAGCAGACATTTCCAGCATAACAGAAGCAGTGCCTAGTGAGAGTGAGCCCCCTGCT
CTTCAAAACAACCTCTTGTCTCCTCTTCTGACCGGGACAGAGTCACCATTTGATTTGGAACAGCAGTGGCAAGATCTCATGTCCATCATG
GAAATGCAGGCATTTGAGGAGACTCATCTGACCTCCCTTGACCCAGTGAAACAGTTTGCTGCCTGGTTTGAGGAGGCTGTTCAGTGTCCT
GACATAGGGGAAGCCAATGCCATGTGTCTGGCTACCTGCACCAGAGATGGAAAACCCTCTGCTCGCATGTTGCTGCTGAAGGGCTTCGGG
AAAGATGGCTTCCGCTTCTTCACTAACTTCGAGAGTCGAAAAGGAAAAGAGCTGGTGCGTGTGGAAGGCCCTGTGAAGAAACTGCCTGAG
GAGGAGGCTGAGTGCTACTTCCACTCCCGCCCCAAGAGCAGCCAGATTGGGGCTGTGGTCAGCCACCAGAGTTCTGTGATCCCTGATCGG
GAGTATCTGAGAAAGAAAAATGAGGAACTGGAACAGCTCTACCAGGATCAAGAGGTGCCCAAGCCAAAATCCTGGGGTGGCTATGTCCTG
TACCCTCAGGTGATGGAGTTCTGGCAAGGTCAAACCAACCGCCTGCATGACCGGATAGTCTTTCGGCGGGGCCTACCCACAGGAGATTCC
CCTTTGGGGCCCATGACCCACCGCGGGGAGGAAGACTGGCTCTATGAGAGACTTGCACCTTAACTCTGGGACCTGCTGGCCCAGAGTGGA
GCTAGGGCTAGGTGTCAAGAGAGGGTGTGGGATTGGGACCCAGGCCCTTCTTTCTAAACTCAACCCATTTCCCTCCCTACCCCTTATCTT
CAGGACTCTTCAGAGCTAATCCTCTAAGTTCTCTGTACTCAGTTGGTTCTCAGTTAGCTGGTCAAGTGGAGTGTAATGGTGGCGTAGAGA
ATCACAAATGGAAAATAATTCCATAATTATTTTTTTGACCTTGCCTATGATTGATTAGGATAGCTCCCTCTAGGGGTAGCAGCCGGTGTG

>In-frame_ENST00000582155_ENST00000544840_TCGA-EY-A2OQ-01A_NFE2L1_chr17_46134864_+_PNPO_chr17_46020672_length(amino acids)=333AA_start in transcript=51_stop in transcript=1052
MGWESHLTAASADIDLIDILWRQDIDLGAGREVFDYSHRQKEQDVEKELRDGGEQDTWAGEGAEALARNLLVDGETGESFPAQFPADISS
ITEAVPSESEPPALQNNLLSPLLTGTESPFDLEQQWQDLMSIMEMQAFEETHLTSLDPVKQFAAWFEEAVQCPDIGEANAMCLATCTRDG
KPSARMLLLKGFGKDGFRFFTNFESRKGKELVRVEGPVKKLPEEEAECYFHSRPKSSQIGAVVSHQSSVIPDREYLRKKNEELEQLYQDQ

--------------------------------------------------------------
>In-frame_ENST00000582155_ENST00000434554_TCGA-EY-A2OQ-01A_NFE2L1_chr17_46134864_+_PNPO_chr17_46020672_length(transcript)=1426nt_BP=459nt
AGGATAGGCCCAGGAGGGAGCTTGCTTTCCTCTGCAGCTTGAGCACGGAGCATGGGGTGGGAGTCCCATCTCACTGCAGCCTCTGCGGAC
ATAGATCTGATTGACATCCTTTGGCGACAGGATATTGATCTGGGGGCTGGGCGTGAGGTTTTTGACTATAGTCACCGCCAGAAGGAGCAG
GATGTGGAGAAGGAGCTGCGAGATGGAGGCGAGCAGGACACCTGGGCAGGCGAGGGCGCGGAAGCTCTGGCACGGAACCTGCTAGTGGAT
GGAGAGACTGGGGAGAGCTTCCCTGCACAGTTTCCAGCAGACATTTCCAGCATAACAGAAGCAGTGCCTAGTGAGAGTGAGCCCCCTGCT
CTTCAAAACAACCTCTTGTCTCCTCTTCTGACCGGGACAGAGTCACCATTTGATTTGGAACAGCAGTGGCAAGATCTCATGTCCATCATG
GAAATGCAGGCATTTGAGGAGACTCATCTGACCTCCCTTGACCCAGTGAAACAGTTTGCTGCCTGGTTTGAGGAGGCTGTTCAGTGTCCT
GACATAGGGGAAGCCAATGCCATGTGTCTGGCTACCTGCACCAGAGATGGAAAACCCTCTGCTCGCATGTTGCTGCTGAAGGGCTTCGGG
AAAGATGGCTTCCGCTTCTTCACTAACTTCGAGAGTCGAAAAGGAAAAGAGCTGGACTCTAATCCCTTTGCTTCCCTTGTCTTCTACTGG
GAGCCACTTAACCGTCAGTATCTGAGAAAGAAAAATGAGGAACTGGAACAGCTCTACCAGGATCAAGAGGTGCCCAAGCCAAAATCCTGG
GGTGGCTATGTCCTGTACCCTCAGGTGATGGAGTTCTGGCAAGGTCAAACCAACCGCCTGCATGACCGGATAGTCTTTCGGCGGGGCCTA
CCCACAGGAGATTCCCCTTTGGGGCCCATGACCCACCGCGGGGAGGAAGACTGGCTCTATGAGAGACTTGCACCTTAACTCTGGGACCTG
CTGGCCCAGAGTGGAGCTAGGGCTAGGTGTCAAGAGAGGGTGTGGGATTGGGACCCAGGCCCTTCTTTCTAAACTCAACCCATTTCCCTC
CCTACCCCTTATCTTCAGGACTCTTCAGAGCTAATCCTCTAAGTTCTCTGTACTCAGTTGGTTCTCAGTTAGCTGGTCAAGTGGAGTGTA
ATGGTGGCGTAGAGAATCACAAATGGAAAATAATTCCATAATTATTTTTTTGACCTTGCCTATGATTGATTAGGATAGCTCCCTCTAGGG
GTAGCAGCCGGTGTGACTCCCTTTCTGGTGACAGACAGGGCCCCAGCAGCCCTGTCTGTTACCATGTGAGTCATACTGGCCAAAGCTTAG

>In-frame_ENST00000582155_ENST00000434554_TCGA-EY-A2OQ-01A_NFE2L1_chr17_46134864_+_PNPO_chr17_46020672_length(amino acids)=308AA_start in transcript=51_stop in transcript=977
MGWESHLTAASADIDLIDILWRQDIDLGAGREVFDYSHRQKEQDVEKELRDGGEQDTWAGEGAEALARNLLVDGETGESFPAQFPADISS
ITEAVPSESEPPALQNNLLSPLLTGTESPFDLEQQWQDLMSIMEMQAFEETHLTSLDPVKQFAAWFEEAVQCPDIGEANAMCLATCTRDG
KPSARMLLLKGFGKDGFRFFTNFESRKGKELDSNPFASLVFYWEPLNRQYLRKKNEELEQLYQDQEVPKPKSWGGYVLYPQVMEFWQGQT

--------------------------------------------------------------
>In-frame_ENST00000582155_ENST00000225573_TCGA-EY-A2OQ-01A_NFE2L1_chr17_46134864_+_PNPO_chr17_46020672_length(transcript)=2613nt_BP=459nt
AGGATAGGCCCAGGAGGGAGCTTGCTTTCCTCTGCAGCTTGAGCACGGAGCATGGGGTGGGAGTCCCATCTCACTGCAGCCTCTGCGGAC
ATAGATCTGATTGACATCCTTTGGCGACAGGATATTGATCTGGGGGCTGGGCGTGAGGTTTTTGACTATAGTCACCGCCAGAAGGAGCAG
GATGTGGAGAAGGAGCTGCGAGATGGAGGCGAGCAGGACACCTGGGCAGGCGAGGGCGCGGAAGCTCTGGCACGGAACCTGCTAGTGGAT
GGAGAGACTGGGGAGAGCTTCCCTGCACAGTTTCCAGCAGACATTTCCAGCATAACAGAAGCAGTGCCTAGTGAGAGTGAGCCCCCTGCT
CTTCAAAACAACCTCTTGTCTCCTCTTCTGACCGGGACAGAGTCACCATTTGATTTGGAACAGCAGTGGCAAGATCTCATGTCCATCATG
GAAATGCAGGCATTTGAGGAGACTCATCTGACCTCCCTTGACCCAGTGAAACAGTTTGCTGCCTGGTTTGAGGAGGCTGTTCAGTGTCCT
GACATAGGGGAAGCCAATGCCATGTGTCTGGCTACCTGCACCAGAGATGGAAAACCCTCTGCTCGCATGTTGCTGCTGAAGGGCTTCGGG
AAAGATGGCTTCCGCTTCTTCACTAACTTCGAGAGTCGAAAAGGAAAAGAGCTGGACTCTAATCCCTTTGCTTCCCTTGTCTTCTACTGG
GAGCCACTTAACCGTCAGGTGCGTGTGGAAGGCCCTGTGAAGAAACTGCCTGAGGAGGAGGCTGAGTGCTACTTCCACTCCCGCCCCAAG
AGCAGCCAGATTGGGGCTGTGGTCAGCCACCAGAGTTCTGTGATCCCTGATCGGGAGTATCTGAGAAAGAAAAATGAGGAACTGGAACAG
CTCTACCAGGATCAAGAGGTGCCCAAGCCAAAATCCTGGGGTGGCTATGTCCTGTACCCTCAGGTGATGGAGTTCTGGCAAGGTCAAACC
AACCGCCTGCATGACCGGATAGTCTTTCGGCGGGGCCTACCCACAGGAGATTCCCCTTTGGGGCCCATGACCCACCGCGGGGAGGAAGAC
TGGCTCTATGAGAGACTTGCACCTTAACTCTGGGACCTGCTGGCCCAGAGTGGAGCTAGGGCTAGGTGTCAAGAGAGGGTGTGGGATTGG
GACCCAGGCCCTTCTTTCTAAACTCAACCCATTTCCCTCCCTACCCCTTATCTTCAGGACTCTTCAGAGCTAATCCTCTAAGTTCTCTGT
ACTCAGTTGGTTCTCAGTTAGCTGGTCAAGTGGAGTGTAATGGTGGCGTAGAGAATCACAAATGGAAAATAATTCCATAATTATTTTTTT
GACCTTGCCTATGATTGATTAGGATAGCTCCCTCTAGGGGTAGCAGCCGGTGTGACTCCCTTTCTGGTGACAGACAGGGCCCCAGCAGCC
CTGTCTGTTACCATGTGAGTCATACTGGCCAAAGCTTAGTCCTAGCATATGCACCTGAGCCAACCTGGCCAATCAGATTGTTTTGTCAAT
AATTTGAAATTTGAACTGGAGAGATCCAGAACCTTGGGAGTCATTAAAGCCAAGTCATTCATAGCAGCCAGGAAACAATAGGAACCAAAA
GCCTCTGCCTGCTGCTATTGCAATTCCCAGGATCTCTCCTTCCCTGGATCCCTCCCTCCCAGGTCTGGGCTGTGCAGTTCCTCCCCCTGC
CTTAAAACACCCCACTATCTCTGTAAAGTCTCTCTCTCTCTTTTTTTTTTTTTTACTTAATCTAGCTAGAATCTATTTCTGTTGATTACA
ACTTAACTAACTCATTTACGGATAGGACTTTTTTTTTTCTTTTTTTCTTTTTTCTTTTCTTTTTTTTTTTTGAGATGGAGTCTCACTCTG
TCACCCAGGCTGGAGTGCAGTGGTGTGATCTTGGCTCACTGCAACCTCTGCCTCCCAGGTTCAAGCAATTCTCCTGCCTCAGCCTCCCAA
GTAGCTGGGACTACAGGCACACGCCACCACACCCAACTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTGGCCAGGATTGT
CTCCATCTCTTGACCTTGTGATCCACCCACCTCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCACACCCAGCGAGACGGGGT
TTCATTATGTTGGCCAGGCTGGTCTCCAACTCCTGACCTAAAGTGATCTGCCCGCCTTGGCCTCCCAAAGTGCTGGGATTACAGACATGA
GCCACCACGCTTGGCCGGGATAGTATATTTTTATAGCACTTCCCCTACTGATTGCTGCCTTCTCTGTGGCTACAAGGGACCCACAGAATT
ACAGGGAAGTTACAGGGAAGCAGGTTTCATCTCAATATTGGGAGAGATTTCAAACAATCACACCTGCCTGAGAAGGAGTGGGCTGTCACT
AGGAATTTTTATTCCCAGTCCGTCAGGAATTTTGTAGAAGGGCTTCATGTGCTGGTACCAATAGGACAGGAAGATTTTAATCAGCTTTAC
TATCTATGTTTTTTTATGGAAACTGTGTGTATGTATACATACATTTTCCAAAAAGAAAAATTAAATGATTATAGAGATTATGTTTTTCAG

>In-frame_ENST00000582155_ENST00000225573_TCGA-EY-A2OQ-01A_NFE2L1_chr17_46134864_+_PNPO_chr17_46020672_length(amino acids)=351AA_start in transcript=51_stop in transcript=1106
MGWESHLTAASADIDLIDILWRQDIDLGAGREVFDYSHRQKEQDVEKELRDGGEQDTWAGEGAEALARNLLVDGETGESFPAQFPADISS
ITEAVPSESEPPALQNNLLSPLLTGTESPFDLEQQWQDLMSIMEMQAFEETHLTSLDPVKQFAAWFEEAVQCPDIGEANAMCLATCTRDG
KPSARMLLLKGFGKDGFRFFTNFESRKGKELDSNPFASLVFYWEPLNRQVRVEGPVKKLPEEEAECYFHSRPKSSQIGAVVSHQSSVIPD

--------------------------------------------------------------
>In-frame_ENST00000583378_ENST00000544840_TCGA-EY-A2OQ-01A_NFE2L1_chr17_46134864_+_PNPO_chr17_46020672_length(transcript)=1362nt_BP=409nt
GAGCTTGCTTTCCTCTGCAGCTTGAGCACGGAGCATGGGGTGGGAGTCCCATCTCACTGCAGCCTCTGCGGATATTGATCTGGGGGCTGG
GCGTGAGGTTTTTGACTATAGTCACCGCCAGAAGGAGCAGGATGTGGAGAAGGAGCTGCGAGATGGAGGCGAGCAGGACACCTGGGCAGG
CGAGGGCGCGGAAGCTCTGGCACGGAACCTGCTAGTGGATGGAGAGACTGGGGAGAGCTTCCCTGCACAGTTTCCAGCAGACATTTCCAG
CATAACAGAAGCAGTGCCTAGTGAGAGTGAGCCCCCTGCTCTTCAAAACAACCTCTTGTCTCCTCTTCTGACCGGGACAGAGTCACCATT
TGATTTGGAACAGCAGTGGCAAGATCTCATGTCCATCATGGAAATGCAGGCATTTGAGGAGACTCATCTGACCTCCCTTGACCCAGTGAA
ACAGTTTGCTGCCTGGTTTGAGGAGGCTGTTCAGTGTCCTGACATAGGGGAAGCCAATGCCATGTGTCTGGCTACCTGCACCAGAGATGG
AAAACCCTCTGCTCGCATGTTGCTGCTGAAGGGCTTCGGGAAAGATGGCTTCCGCTTCTTCACTAACTTCGAGAGTCGAAAAGGAAAAGA
GCTGGTGCGTGTGGAAGGCCCTGTGAAGAAACTGCCTGAGGAGGAGGCTGAGTGCTACTTCCACTCCCGCCCCAAGAGCAGCCAGATTGG
GGCTGTGGTCAGCCACCAGAGTTCTGTGATCCCTGATCGGGAGTATCTGAGAAAGAAAAATGAGGAACTGGAACAGCTCTACCAGGATCA
AGAGGTGCCCAAGCCAAAATCCTGGGGTGGCTATGTCCTGTACCCTCAGGTGATGGAGTTCTGGCAAGGTCAAACCAACCGCCTGCATGA
CCGGATAGTCTTTCGGCGGGGCCTACCCACAGGAGATTCCCCTTTGGGGCCCATGACCCACCGCGGGGAGGAAGACTGGCTCTATGAGAG
ACTTGCACCTTAACTCTGGGACCTGCTGGCCCAGAGTGGAGCTAGGGCTAGGTGTCAAGAGAGGGTGTGGGATTGGGACCCAGGCCCTTC
TTTCTAAACTCAACCCATTTCCCTCCCTACCCCTTATCTTCAGGACTCTTCAGAGCTAATCCTCTAAGTTCTCTGTACTCAGTTGGTTCT
CAGTTAGCTGGTCAAGTGGAGTGTAATGGTGGCGTAGAGAATCACAAATGGAAAATAATTCCATAATTATTTTTTTGACCTTGCCTATGA
TTGATTAGGATAGCTCCCTCTAGGGGTAGCAGCCGGTGTGACTCCCTTTCTGGTGACAGACAGGGCCCCAGCAGCCCTGTCTGTTACCAT

>In-frame_ENST00000583378_ENST00000544840_TCGA-EY-A2OQ-01A_NFE2L1_chr17_46134864_+_PNPO_chr17_46020672_length(amino acids)=322AA_start in transcript=34_stop in transcript=1002
MGWESHLTAASADIDLGAGREVFDYSHRQKEQDVEKELRDGGEQDTWAGEGAEALARNLLVDGETGESFPAQFPADISSITEAVPSESEP
PALQNNLLSPLLTGTESPFDLEQQWQDLMSIMEMQAFEETHLTSLDPVKQFAAWFEEAVQCPDIGEANAMCLATCTRDGKPSARMLLLKG
FGKDGFRFFTNFESRKGKELVRVEGPVKKLPEEEAECYFHSRPKSSQIGAVVSHQSSVIPDREYLRKKNEELEQLYQDQEVPKPKSWGGY

--------------------------------------------------------------
>In-frame_ENST00000583378_ENST00000434554_TCGA-EY-A2OQ-01A_NFE2L1_chr17_46134864_+_PNPO_chr17_46020672_length(transcript)=1376nt_BP=409nt
GAGCTTGCTTTCCTCTGCAGCTTGAGCACGGAGCATGGGGTGGGAGTCCCATCTCACTGCAGCCTCTGCGGATATTGATCTGGGGGCTGG
GCGTGAGGTTTTTGACTATAGTCACCGCCAGAAGGAGCAGGATGTGGAGAAGGAGCTGCGAGATGGAGGCGAGCAGGACACCTGGGCAGG
CGAGGGCGCGGAAGCTCTGGCACGGAACCTGCTAGTGGATGGAGAGACTGGGGAGAGCTTCCCTGCACAGTTTCCAGCAGACATTTCCAG
CATAACAGAAGCAGTGCCTAGTGAGAGTGAGCCCCCTGCTCTTCAAAACAACCTCTTGTCTCCTCTTCTGACCGGGACAGAGTCACCATT
TGATTTGGAACAGCAGTGGCAAGATCTCATGTCCATCATGGAAATGCAGGCATTTGAGGAGACTCATCTGACCTCCCTTGACCCAGTGAA
ACAGTTTGCTGCCTGGTTTGAGGAGGCTGTTCAGTGTCCTGACATAGGGGAAGCCAATGCCATGTGTCTGGCTACCTGCACCAGAGATGG
AAAACCCTCTGCTCGCATGTTGCTGCTGAAGGGCTTCGGGAAAGATGGCTTCCGCTTCTTCACTAACTTCGAGAGTCGAAAAGGAAAAGA
GCTGGACTCTAATCCCTTTGCTTCCCTTGTCTTCTACTGGGAGCCACTTAACCGTCAGTATCTGAGAAAGAAAAATGAGGAACTGGAACA
GCTCTACCAGGATCAAGAGGTGCCCAAGCCAAAATCCTGGGGTGGCTATGTCCTGTACCCTCAGGTGATGGAGTTCTGGCAAGGTCAAAC
CAACCGCCTGCATGACCGGATAGTCTTTCGGCGGGGCCTACCCACAGGAGATTCCCCTTTGGGGCCCATGACCCACCGCGGGGAGGAAGA
CTGGCTCTATGAGAGACTTGCACCTTAACTCTGGGACCTGCTGGCCCAGAGTGGAGCTAGGGCTAGGTGTCAAGAGAGGGTGTGGGATTG
GGACCCAGGCCCTTCTTTCTAAACTCAACCCATTTCCCTCCCTACCCCTTATCTTCAGGACTCTTCAGAGCTAATCCTCTAAGTTCTCTG
TACTCAGTTGGTTCTCAGTTAGCTGGTCAAGTGGAGTGTAATGGTGGCGTAGAGAATCACAAATGGAAAATAATTCCATAATTATTTTTT
TGACCTTGCCTATGATTGATTAGGATAGCTCCCTCTAGGGGTAGCAGCCGGTGTGACTCCCTTTCTGGTGACAGACAGGGCCCCAGCAGC
CCTGTCTGTTACCATGTGAGTCATACTGGCCAAAGCTTAGTCCTAGCATATGCACCTGAGCCAACCTGGCCAATCAGATTGTTTTGTCAA

>In-frame_ENST00000583378_ENST00000434554_TCGA-EY-A2OQ-01A_NFE2L1_chr17_46134864_+_PNPO_chr17_46020672_length(amino acids)=297AA_start in transcript=34_stop in transcript=927
MGWESHLTAASADIDLGAGREVFDYSHRQKEQDVEKELRDGGEQDTWAGEGAEALARNLLVDGETGESFPAQFPADISSITEAVPSESEP
PALQNNLLSPLLTGTESPFDLEQQWQDLMSIMEMQAFEETHLTSLDPVKQFAAWFEEAVQCPDIGEANAMCLATCTRDGKPSARMLLLKG
FGKDGFRFFTNFESRKGKELDSNPFASLVFYWEPLNRQYLRKKNEELEQLYQDQEVPKPKSWGGYVLYPQVMEFWQGQTNRLHDRIVFRR

--------------------------------------------------------------
>In-frame_ENST00000583378_ENST00000225573_TCGA-EY-A2OQ-01A_NFE2L1_chr17_46134864_+_PNPO_chr17_46020672_length(transcript)=2563nt_BP=409nt
GAGCTTGCTTTCCTCTGCAGCTTGAGCACGGAGCATGGGGTGGGAGTCCCATCTCACTGCAGCCTCTGCGGATATTGATCTGGGGGCTGG
GCGTGAGGTTTTTGACTATAGTCACCGCCAGAAGGAGCAGGATGTGGAGAAGGAGCTGCGAGATGGAGGCGAGCAGGACACCTGGGCAGG
CGAGGGCGCGGAAGCTCTGGCACGGAACCTGCTAGTGGATGGAGAGACTGGGGAGAGCTTCCCTGCACAGTTTCCAGCAGACATTTCCAG
CATAACAGAAGCAGTGCCTAGTGAGAGTGAGCCCCCTGCTCTTCAAAACAACCTCTTGTCTCCTCTTCTGACCGGGACAGAGTCACCATT
TGATTTGGAACAGCAGTGGCAAGATCTCATGTCCATCATGGAAATGCAGGCATTTGAGGAGACTCATCTGACCTCCCTTGACCCAGTGAA
ACAGTTTGCTGCCTGGTTTGAGGAGGCTGTTCAGTGTCCTGACATAGGGGAAGCCAATGCCATGTGTCTGGCTACCTGCACCAGAGATGG
AAAACCCTCTGCTCGCATGTTGCTGCTGAAGGGCTTCGGGAAAGATGGCTTCCGCTTCTTCACTAACTTCGAGAGTCGAAAAGGAAAAGA
GCTGGACTCTAATCCCTTTGCTTCCCTTGTCTTCTACTGGGAGCCACTTAACCGTCAGGTGCGTGTGGAAGGCCCTGTGAAGAAACTGCC
TGAGGAGGAGGCTGAGTGCTACTTCCACTCCCGCCCCAAGAGCAGCCAGATTGGGGCTGTGGTCAGCCACCAGAGTTCTGTGATCCCTGA
TCGGGAGTATCTGAGAAAGAAAAATGAGGAACTGGAACAGCTCTACCAGGATCAAGAGGTGCCCAAGCCAAAATCCTGGGGTGGCTATGT
CCTGTACCCTCAGGTGATGGAGTTCTGGCAAGGTCAAACCAACCGCCTGCATGACCGGATAGTCTTTCGGCGGGGCCTACCCACAGGAGA
TTCCCCTTTGGGGCCCATGACCCACCGCGGGGAGGAAGACTGGCTCTATGAGAGACTTGCACCTTAACTCTGGGACCTGCTGGCCCAGAG
TGGAGCTAGGGCTAGGTGTCAAGAGAGGGTGTGGGATTGGGACCCAGGCCCTTCTTTCTAAACTCAACCCATTTCCCTCCCTACCCCTTA
TCTTCAGGACTCTTCAGAGCTAATCCTCTAAGTTCTCTGTACTCAGTTGGTTCTCAGTTAGCTGGTCAAGTGGAGTGTAATGGTGGCGTA
GAGAATCACAAATGGAAAATAATTCCATAATTATTTTTTTGACCTTGCCTATGATTGATTAGGATAGCTCCCTCTAGGGGTAGCAGCCGG
TGTGACTCCCTTTCTGGTGACAGACAGGGCCCCAGCAGCCCTGTCTGTTACCATGTGAGTCATACTGGCCAAAGCTTAGTCCTAGCATAT
GCACCTGAGCCAACCTGGCCAATCAGATTGTTTTGTCAATAATTTGAAATTTGAACTGGAGAGATCCAGAACCTTGGGAGTCATTAAAGC
CAAGTCATTCATAGCAGCCAGGAAACAATAGGAACCAAAAGCCTCTGCCTGCTGCTATTGCAATTCCCAGGATCTCTCCTTCCCTGGATC
CCTCCCTCCCAGGTCTGGGCTGTGCAGTTCCTCCCCCTGCCTTAAAACACCCCACTATCTCTGTAAAGTCTCTCTCTCTCTTTTTTTTTT
TTTTACTTAATCTAGCTAGAATCTATTTCTGTTGATTACAACTTAACTAACTCATTTACGGATAGGACTTTTTTTTTTCTTTTTTTCTTT
TTTCTTTTCTTTTTTTTTTTTGAGATGGAGTCTCACTCTGTCACCCAGGCTGGAGTGCAGTGGTGTGATCTTGGCTCACTGCAACCTCTG
CCTCCCAGGTTCAAGCAATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGACTACAGGCACACGCCACCACACCCAACTAATTTTTGTATT
TTTAGTAGAGATGGGGTTTCACCATGTTGGCCAGGATTGTCTCCATCTCTTGACCTTGTGATCCACCCACCTCAGCCTCCCAAAGTGCTG
GGATTACAGGCATGAGCCACCACACCCAGCGAGACGGGGTTTCATTATGTTGGCCAGGCTGGTCTCCAACTCCTGACCTAAAGTGATCTG
CCCGCCTTGGCCTCCCAAAGTGCTGGGATTACAGACATGAGCCACCACGCTTGGCCGGGATAGTATATTTTTATAGCACTTCCCCTACTG
ATTGCTGCCTTCTCTGTGGCTACAAGGGACCCACAGAATTACAGGGAAGTTACAGGGAAGCAGGTTTCATCTCAATATTGGGAGAGATTT
CAAACAATCACACCTGCCTGAGAAGGAGTGGGCTGTCACTAGGAATTTTTATTCCCAGTCCGTCAGGAATTTTGTAGAAGGGCTTCATGT
GCTGGTACCAATAGGACAGGAAGATTTTAATCAGCTTTACTATCTATGTTTTTTTATGGAAACTGTGTGTATGTATACATACATTTTCCA

>In-frame_ENST00000583378_ENST00000225573_TCGA-EY-A2OQ-01A_NFE2L1_chr17_46134864_+_PNPO_chr17_46020672_length(amino acids)=340AA_start in transcript=34_stop in transcript=1056
MGWESHLTAASADIDLGAGREVFDYSHRQKEQDVEKELRDGGEQDTWAGEGAEALARNLLVDGETGESFPAQFPADISSITEAVPSESEP
PALQNNLLSPLLTGTESPFDLEQQWQDLMSIMEMQAFEETHLTSLDPVKQFAAWFEEAVQCPDIGEANAMCLATCTRDGKPSARMLLLKG
FGKDGFRFFTNFESRKGKELDSNPFASLVFYWEPLNRQVRVEGPVKKLPEEEAECYFHSRPKSSQIGAVVSHQSSVIPDREYLRKKNEEL

--------------------------------------------------------------
>In-frame_ENST00000536222_ENST00000544840_TCGA-EY-A2OQ-01A_NFE2L1_chr17_46134864_+_PNPO_chr17_46020672_length(transcript)=1766nt_BP=813nt
AGCTTGAGCACGGAGCATGGGGTGGGAGTCCCATCTCACTGCAGCCTCTGCGGTGAGCTCAGGGTGGGGGCAGCTGGGCGCCTGAGTGGA
ACTGGGGTTGTGAGGTGGGAGGGGGCTGCTCAAGGATGGAGGAAGGGGGCTGGCTGGGCCGCCCAGGCAGCAGCACGGGCGGGGCACCCT
CCTCAGGCCCCTCGGAGCTAGCAAGGGGCCACCCTTCCAGCCTGGTGTGCTCCCTGAAAGCCAAGAGCTCCTTGCAGCCCCCTGTCCGGC
TTCCCGGCACCGGCTGCCCTGGGGCTCATCTCGCAGACCATGACCCGCCTGGACCGCAGCTCTCACAGTGGTGGGGGCCATGCCAAAGGC
AGCCGGCCCCTTAACTCTTTGCTGGCTGGTCACCGGGTGGCCCAGCCCGCCTCTGCTCCTGGGTCCAGGGCTTCTGTTCAGGACATAGAT
CTGATTGACATCCTTTGGCGACAGGATATTGATCTGGGGGCTGGGCGTGAGGTTTTTGACTATAGTCACCGCCAGAAGGAGCAGGATGTG
GAGAAGGAGCTGCGAGATGGAGGCGAGCAGGACACCTGGGCAGGCGAGGGCGCGGAAGCTCTGGCACGGAACCTGCTAGTGGATGGAGAG
ACTGGGGAGAGCTTCCCTGCACAGTTTCCAGCAGACATTTCCAGCATAACAGAAGCAGTGCCTAGTGAGAGTGAGCCCCCTGCTCTTCAA
AACAACCTCTTGTCTCCTCTTCTGACCGGGACAGAGTCACCATTTGATTTGGAACAGCAGTGGCAAGATCTCATGTCCATCATGGAAATG
CAGGCATTTGAGGAGACTCATCTGACCTCCCTTGACCCAGTGAAACAGTTTGCTGCCTGGTTTGAGGAGGCTGTTCAGTGTCCTGACATA
GGGGAAGCCAATGCCATGTGTCTGGCTACCTGCACCAGAGATGGAAAACCCTCTGCTCGCATGTTGCTGCTGAAGGGCTTCGGGAAAGAT
GGCTTCCGCTTCTTCACTAACTTCGAGAGTCGAAAAGGAAAAGAGCTGGTGCGTGTGGAAGGCCCTGTGAAGAAACTGCCTGAGGAGGAG
GCTGAGTGCTACTTCCACTCCCGCCCCAAGAGCAGCCAGATTGGGGCTGTGGTCAGCCACCAGAGTTCTGTGATCCCTGATCGGGAGTAT
CTGAGAAAGAAAAATGAGGAACTGGAACAGCTCTACCAGGATCAAGAGGTGCCCAAGCCAAAATCCTGGGGTGGCTATGTCCTGTACCCT
CAGGTGATGGAGTTCTGGCAAGGTCAAACCAACCGCCTGCATGACCGGATAGTCTTTCGGCGGGGCCTACCCACAGGAGATTCCCCTTTG
GGGCCCATGACCCACCGCGGGGAGGAAGACTGGCTCTATGAGAGACTTGCACCTTAACTCTGGGACCTGCTGGCCCAGAGTGGAGCTAGG
GCTAGGTGTCAAGAGAGGGTGTGGGATTGGGACCCAGGCCCTTCTTTCTAAACTCAACCCATTTCCCTCCCTACCCCTTATCTTCAGGAC
TCTTCAGAGCTAATCCTCTAAGTTCTCTGTACTCAGTTGGTTCTCAGTTAGCTGGTCAAGTGGAGTGTAATGGTGGCGTAGAGAATCACA
AATGGAAAATAATTCCATAATTATTTTTTTGACCTTGCCTATGATTGATTAGGATAGCTCCCTCTAGGGGTAGCAGCCGGTGTGACTCCC

>In-frame_ENST00000536222_ENST00000544840_TCGA-EY-A2OQ-01A_NFE2L1_chr17_46134864_+_PNPO_chr17_46020672_length(amino acids)=381AA_start in transcript=261_stop in transcript=1406
MSGFPAPAALGLISQTMTRLDRSSHSGGGHAKGSRPLNSLLAGHRVAQPASAPGSRASVQDIDLIDILWRQDIDLGAGREVFDYSHRQKE
QDVEKELRDGGEQDTWAGEGAEALARNLLVDGETGESFPAQFPADISSITEAVPSESEPPALQNNLLSPLLTGTESPFDLEQQWQDLMSI
MEMQAFEETHLTSLDPVKQFAAWFEEAVQCPDIGEANAMCLATCTRDGKPSARMLLLKGFGKDGFRFFTNFESRKGKELVRVEGPVKKLP
EEEAECYFHSRPKSSQIGAVVSHQSSVIPDREYLRKKNEELEQLYQDQEVPKPKSWGGYVLYPQVMEFWQGQTNRLHDRIVFRRGLPTGD

--------------------------------------------------------------
>In-frame_ENST00000536222_ENST00000434554_TCGA-EY-A2OQ-01A_NFE2L1_chr17_46134864_+_PNPO_chr17_46020672_length(transcript)=1780nt_BP=813nt
AGCTTGAGCACGGAGCATGGGGTGGGAGTCCCATCTCACTGCAGCCTCTGCGGTGAGCTCAGGGTGGGGGCAGCTGGGCGCCTGAGTGGA
ACTGGGGTTGTGAGGTGGGAGGGGGCTGCTCAAGGATGGAGGAAGGGGGCTGGCTGGGCCGCCCAGGCAGCAGCACGGGCGGGGCACCCT
CCTCAGGCCCCTCGGAGCTAGCAAGGGGCCACCCTTCCAGCCTGGTGTGCTCCCTGAAAGCCAAGAGCTCCTTGCAGCCCCCTGTCCGGC
TTCCCGGCACCGGCTGCCCTGGGGCTCATCTCGCAGACCATGACCCGCCTGGACCGCAGCTCTCACAGTGGTGGGGGCCATGCCAAAGGC
AGCCGGCCCCTTAACTCTTTGCTGGCTGGTCACCGGGTGGCCCAGCCCGCCTCTGCTCCTGGGTCCAGGGCTTCTGTTCAGGACATAGAT
CTGATTGACATCCTTTGGCGACAGGATATTGATCTGGGGGCTGGGCGTGAGGTTTTTGACTATAGTCACCGCCAGAAGGAGCAGGATGTG
GAGAAGGAGCTGCGAGATGGAGGCGAGCAGGACACCTGGGCAGGCGAGGGCGCGGAAGCTCTGGCACGGAACCTGCTAGTGGATGGAGAG
ACTGGGGAGAGCTTCCCTGCACAGTTTCCAGCAGACATTTCCAGCATAACAGAAGCAGTGCCTAGTGAGAGTGAGCCCCCTGCTCTTCAA
AACAACCTCTTGTCTCCTCTTCTGACCGGGACAGAGTCACCATTTGATTTGGAACAGCAGTGGCAAGATCTCATGTCCATCATGGAAATG
CAGGCATTTGAGGAGACTCATCTGACCTCCCTTGACCCAGTGAAACAGTTTGCTGCCTGGTTTGAGGAGGCTGTTCAGTGTCCTGACATA
GGGGAAGCCAATGCCATGTGTCTGGCTACCTGCACCAGAGATGGAAAACCCTCTGCTCGCATGTTGCTGCTGAAGGGCTTCGGGAAAGAT
GGCTTCCGCTTCTTCACTAACTTCGAGAGTCGAAAAGGAAAAGAGCTGGACTCTAATCCCTTTGCTTCCCTTGTCTTCTACTGGGAGCCA
CTTAACCGTCAGTATCTGAGAAAGAAAAATGAGGAACTGGAACAGCTCTACCAGGATCAAGAGGTGCCCAAGCCAAAATCCTGGGGTGGC
TATGTCCTGTACCCTCAGGTGATGGAGTTCTGGCAAGGTCAAACCAACCGCCTGCATGACCGGATAGTCTTTCGGCGGGGCCTACCCACA
GGAGATTCCCCTTTGGGGCCCATGACCCACCGCGGGGAGGAAGACTGGCTCTATGAGAGACTTGCACCTTAACTCTGGGACCTGCTGGCC
CAGAGTGGAGCTAGGGCTAGGTGTCAAGAGAGGGTGTGGGATTGGGACCCAGGCCCTTCTTTCTAAACTCAACCCATTTCCCTCCCTACC
CCTTATCTTCAGGACTCTTCAGAGCTAATCCTCTAAGTTCTCTGTACTCAGTTGGTTCTCAGTTAGCTGGTCAAGTGGAGTGTAATGGTG
GCGTAGAGAATCACAAATGGAAAATAATTCCATAATTATTTTTTTGACCTTGCCTATGATTGATTAGGATAGCTCCCTCTAGGGGTAGCA
GCCGGTGTGACTCCCTTTCTGGTGACAGACAGGGCCCCAGCAGCCCTGTCTGTTACCATGTGAGTCATACTGGCCAAAGCTTAGTCCTAG

>In-frame_ENST00000536222_ENST00000434554_TCGA-EY-A2OQ-01A_NFE2L1_chr17_46134864_+_PNPO_chr17_46020672_length(amino acids)=356AA_start in transcript=261_stop in transcript=1331
MSGFPAPAALGLISQTMTRLDRSSHSGGGHAKGSRPLNSLLAGHRVAQPASAPGSRASVQDIDLIDILWRQDIDLGAGREVFDYSHRQKE
QDVEKELRDGGEQDTWAGEGAEALARNLLVDGETGESFPAQFPADISSITEAVPSESEPPALQNNLLSPLLTGTESPFDLEQQWQDLMSI
MEMQAFEETHLTSLDPVKQFAAWFEEAVQCPDIGEANAMCLATCTRDGKPSARMLLLKGFGKDGFRFFTNFESRKGKELDSNPFASLVFY

--------------------------------------------------------------
>In-frame_ENST00000536222_ENST00000225573_TCGA-EY-A2OQ-01A_NFE2L1_chr17_46134864_+_PNPO_chr17_46020672_length(transcript)=2967nt_BP=813nt
AGCTTGAGCACGGAGCATGGGGTGGGAGTCCCATCTCACTGCAGCCTCTGCGGTGAGCTCAGGGTGGGGGCAGCTGGGCGCCTGAGTGGA
ACTGGGGTTGTGAGGTGGGAGGGGGCTGCTCAAGGATGGAGGAAGGGGGCTGGCTGGGCCGCCCAGGCAGCAGCACGGGCGGGGCACCCT
CCTCAGGCCCCTCGGAGCTAGCAAGGGGCCACCCTTCCAGCCTGGTGTGCTCCCTGAAAGCCAAGAGCTCCTTGCAGCCCCCTGTCCGGC
TTCCCGGCACCGGCTGCCCTGGGGCTCATCTCGCAGACCATGACCCGCCTGGACCGCAGCTCTCACAGTGGTGGGGGCCATGCCAAAGGC
AGCCGGCCCCTTAACTCTTTGCTGGCTGGTCACCGGGTGGCCCAGCCCGCCTCTGCTCCTGGGTCCAGGGCTTCTGTTCAGGACATAGAT
CTGATTGACATCCTTTGGCGACAGGATATTGATCTGGGGGCTGGGCGTGAGGTTTTTGACTATAGTCACCGCCAGAAGGAGCAGGATGTG
GAGAAGGAGCTGCGAGATGGAGGCGAGCAGGACACCTGGGCAGGCGAGGGCGCGGAAGCTCTGGCACGGAACCTGCTAGTGGATGGAGAG
ACTGGGGAGAGCTTCCCTGCACAGTTTCCAGCAGACATTTCCAGCATAACAGAAGCAGTGCCTAGTGAGAGTGAGCCCCCTGCTCTTCAA
AACAACCTCTTGTCTCCTCTTCTGACCGGGACAGAGTCACCATTTGATTTGGAACAGCAGTGGCAAGATCTCATGTCCATCATGGAAATG
CAGGCATTTGAGGAGACTCATCTGACCTCCCTTGACCCAGTGAAACAGTTTGCTGCCTGGTTTGAGGAGGCTGTTCAGTGTCCTGACATA
GGGGAAGCCAATGCCATGTGTCTGGCTACCTGCACCAGAGATGGAAAACCCTCTGCTCGCATGTTGCTGCTGAAGGGCTTCGGGAAAGAT
GGCTTCCGCTTCTTCACTAACTTCGAGAGTCGAAAAGGAAAAGAGCTGGACTCTAATCCCTTTGCTTCCCTTGTCTTCTACTGGGAGCCA
CTTAACCGTCAGGTGCGTGTGGAAGGCCCTGTGAAGAAACTGCCTGAGGAGGAGGCTGAGTGCTACTTCCACTCCCGCCCCAAGAGCAGC
CAGATTGGGGCTGTGGTCAGCCACCAGAGTTCTGTGATCCCTGATCGGGAGTATCTGAGAAAGAAAAATGAGGAACTGGAACAGCTCTAC
CAGGATCAAGAGGTGCCCAAGCCAAAATCCTGGGGTGGCTATGTCCTGTACCCTCAGGTGATGGAGTTCTGGCAAGGTCAAACCAACCGC
CTGCATGACCGGATAGTCTTTCGGCGGGGCCTACCCACAGGAGATTCCCCTTTGGGGCCCATGACCCACCGCGGGGAGGAAGACTGGCTC
TATGAGAGACTTGCACCTTAACTCTGGGACCTGCTGGCCCAGAGTGGAGCTAGGGCTAGGTGTCAAGAGAGGGTGTGGGATTGGGACCCA
GGCCCTTCTTTCTAAACTCAACCCATTTCCCTCCCTACCCCTTATCTTCAGGACTCTTCAGAGCTAATCCTCTAAGTTCTCTGTACTCAG
TTGGTTCTCAGTTAGCTGGTCAAGTGGAGTGTAATGGTGGCGTAGAGAATCACAAATGGAAAATAATTCCATAATTATTTTTTTGACCTT
GCCTATGATTGATTAGGATAGCTCCCTCTAGGGGTAGCAGCCGGTGTGACTCCCTTTCTGGTGACAGACAGGGCCCCAGCAGCCCTGTCT
GTTACCATGTGAGTCATACTGGCCAAAGCTTAGTCCTAGCATATGCACCTGAGCCAACCTGGCCAATCAGATTGTTTTGTCAATAATTTG
AAATTTGAACTGGAGAGATCCAGAACCTTGGGAGTCATTAAAGCCAAGTCATTCATAGCAGCCAGGAAACAATAGGAACCAAAAGCCTCT
GCCTGCTGCTATTGCAATTCCCAGGATCTCTCCTTCCCTGGATCCCTCCCTCCCAGGTCTGGGCTGTGCAGTTCCTCCCCCTGCCTTAAA
ACACCCCACTATCTCTGTAAAGTCTCTCTCTCTCTTTTTTTTTTTTTTACTTAATCTAGCTAGAATCTATTTCTGTTGATTACAACTTAA
CTAACTCATTTACGGATAGGACTTTTTTTTTTCTTTTTTTCTTTTTTCTTTTCTTTTTTTTTTTTGAGATGGAGTCTCACTCTGTCACCC
AGGCTGGAGTGCAGTGGTGTGATCTTGGCTCACTGCAACCTCTGCCTCCCAGGTTCAAGCAATTCTCCTGCCTCAGCCTCCCAAGTAGCT
GGGACTACAGGCACACGCCACCACACCCAACTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTGGCCAGGATTGTCTCCAT
CTCTTGACCTTGTGATCCACCCACCTCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCACACCCAGCGAGACGGGGTTTCATT
ATGTTGGCCAGGCTGGTCTCCAACTCCTGACCTAAAGTGATCTGCCCGCCTTGGCCTCCCAAAGTGCTGGGATTACAGACATGAGCCACC
ACGCTTGGCCGGGATAGTATATTTTTATAGCACTTCCCCTACTGATTGCTGCCTTCTCTGTGGCTACAAGGGACCCACAGAATTACAGGG
AAGTTACAGGGAAGCAGGTTTCATCTCAATATTGGGAGAGATTTCAAACAATCACACCTGCCTGAGAAGGAGTGGGCTGTCACTAGGAAT
TTTTATTCCCAGTCCGTCAGGAATTTTGTAGAAGGGCTTCATGTGCTGGTACCAATAGGACAGGAAGATTTTAATCAGCTTTACTATCTA

>In-frame_ENST00000536222_ENST00000225573_TCGA-EY-A2OQ-01A_NFE2L1_chr17_46134864_+_PNPO_chr17_46020672_length(amino acids)=399AA_start in transcript=261_stop in transcript=1460
MSGFPAPAALGLISQTMTRLDRSSHSGGGHAKGSRPLNSLLAGHRVAQPASAPGSRASVQDIDLIDILWRQDIDLGAGREVFDYSHRQKE
QDVEKELRDGGEQDTWAGEGAEALARNLLVDGETGESFPAQFPADISSITEAVPSESEPPALQNNLLSPLLTGTESPFDLEQQWQDLMSI
MEMQAFEETHLTSLDPVKQFAAWFEEAVQCPDIGEANAMCLATCTRDGKPSARMLLLKGFGKDGFRFFTNFESRKGKELDSNPFASLVFY
WEPLNRQVRVEGPVKKLPEEEAECYFHSRPKSSQIGAVVSHQSSVIPDREYLRKKNEELEQLYQDQEVPKPKSWGGYVLYPQVMEFWQGQ

--------------------------------------------------------------

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Fusion Gene PPI Analysis for NFE2L1-PNPO


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for NFE2L1-PNPO


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for NFE2L1-PNPO


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgenePNPOC1864723Pyridoxamine 5-Prime-Phosphate Oxidase Deficiency4CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
TgenePNPOC0036341Schizophrenia1PSYGENET
TgenePNPOC0038220Status Epilepticus1CTD_human
TgenePNPOC0270823Petit mal status1CTD_human
TgenePNPOC0311335Grand Mal Status Epilepticus1CTD_human
TgenePNPOC0393734Complex Partial Status Epilepticus1CTD_human
TgenePNPOC0557874Global developmental delay1GENOMICS_ENGLAND
TgenePNPOC0751522Status Epilepticus, Subclinical1CTD_human
TgenePNPOC0751523Non-Convulsive Status Epilepticus1CTD_human
TgenePNPOC0751524Simple Partial Status Epilepticus1CTD_human