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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:NFIX-DNM2 (FusionGDB2 ID:58589)

Fusion Gene Summary for NFIX-DNM2

check button Fusion gene summary
Fusion gene informationFusion gene name: NFIX-DNM2
Fusion gene ID: 58589
HgeneTgene
Gene symbol

NFIX

DNM2

Gene ID

4784

1785

Gene namenuclear factor I Xdynamin 2
SynonymsCTF|MRSHSS|NF-I/X|NF1-X|NF1A|SOTOS2CMT2M|CMTDI1|CMTDIB|DI-CMTB|DYN2|DYNII|LCCS5
Cytomap

19p13.13

19p13.2

Type of geneprotein-codingprotein-coding
Descriptionnuclear factor 1 X-typeCCAAT-box-binding transcription factorTGGCA-binding proteinnuclear factor 1/Xdynamin-2dynamin II
Modification date2020032920200329
UniProtAcc.

P50570

Ensembl transtripts involved in fusion geneENST00000397661, ENST00000592199, 
ENST00000587760, ENST00000585575, 
ENST00000360105, ENST00000588228, 
ENST00000587260, ENST00000358552, 
ENST00000588680, 		ENST00000585892, 
ENST00000314646, ENST00000359692, 
ENST00000389253, ENST00000355667, 
ENST00000408974, ENST00000591819, 
Fusion gene scores* DoF score27 X 14 X 16=604819 X 24 X 14=6384
# samples 4234
** MAII scorelog2(42/6048*10)=-3.84799690655495
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(34/6384*10)=-4.23085400008464
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: NFIX [Title/Abstract] AND DNM2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointDNM2(10870487)-NFIX(13135835), # samples:3
NFIX(13106678)-DNM2(10897240), # samples:3
Anticipated loss of major functional domain due to fusion event.DNM2-NFIX seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF.
DNM2-NFIX seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
DNM2-NFIX seems lost the major protein functional domain in Tgene partner, which is a transcription factor due to the frame-shifted ORF.
DNM2-NFIX seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneNFIX

GO:0000122

negative regulation of transcription by RNA polymerase II

19706729

HgeneNFIX

GO:0045944

positive regulation of transcription by RNA polymerase II

19706729

TgeneDNM2

GO:1903526

negative regulation of membrane tubulation

18388313


check buttonFusion gene breakpoints across NFIX (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across DNM2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUSCTCGA-34-8456-01ANFIXchr19

13106678

+DNM2chr19

10897240

+
ChimerDB4LUSCTCGA-34-8456NFIXchr19

13106678

+DNM2chr19

10897240

+
ChimerDB4LUSCTCGA-34-8456-01ANFIXchr19

13106678

-DNM2chr19

10897240

+


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Fusion Gene ORF analysis for NFIX-DNM2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000397661ENST00000585892NFIXchr19

13106678

+DNM2chr19

10897240

+
In-frameENST00000397661ENST00000314646NFIXchr19

13106678

+DNM2chr19

10897240

+
In-frameENST00000397661ENST00000359692NFIXchr19

13106678

+DNM2chr19

10897240

+
In-frameENST00000397661ENST00000389253NFIXchr19

13106678

+DNM2chr19

10897240

+
In-frameENST00000397661ENST00000355667NFIXchr19

13106678

+DNM2chr19

10897240

+
In-frameENST00000397661ENST00000408974NFIXchr19

13106678

+DNM2chr19

10897240

+
5CDS-intronENST00000397661ENST00000591819NFIXchr19

13106678

+DNM2chr19

10897240

+
In-frameENST00000592199ENST00000585892NFIXchr19

13106678

+DNM2chr19

10897240

+
In-frameENST00000592199ENST00000314646NFIXchr19

13106678

+DNM2chr19

10897240

+
In-frameENST00000592199ENST00000359692NFIXchr19

13106678

+DNM2chr19

10897240

+
In-frameENST00000592199ENST00000389253NFIXchr19

13106678

+DNM2chr19

10897240

+
In-frameENST00000592199ENST00000355667NFIXchr19

13106678

+DNM2chr19

10897240

+
In-frameENST00000592199ENST00000408974NFIXchr19

13106678

+DNM2chr19

10897240

+
5CDS-intronENST00000592199ENST00000591819NFIXchr19

13106678

+DNM2chr19

10897240

+
intron-3CDSENST00000587760ENST00000585892NFIXchr19

13106678

+DNM2chr19

10897240

+
intron-3CDSENST00000587760ENST00000314646NFIXchr19

13106678

+DNM2chr19

10897240

+
intron-3CDSENST00000587760ENST00000359692NFIXchr19

13106678

+DNM2chr19

10897240

+
intron-3CDSENST00000587760ENST00000389253NFIXchr19

13106678

+DNM2chr19

10897240

+
intron-3CDSENST00000587760ENST00000355667NFIXchr19

13106678

+DNM2chr19

10897240

+
intron-3CDSENST00000587760ENST00000408974NFIXchr19

13106678

+DNM2chr19

10897240

+
intron-intronENST00000587760ENST00000591819NFIXchr19

13106678

+DNM2chr19

10897240

+
intron-3CDSENST00000585575ENST00000585892NFIXchr19

13106678

+DNM2chr19

10897240

+
intron-3CDSENST00000585575ENST00000314646NFIXchr19

13106678

+DNM2chr19

10897240

+
intron-3CDSENST00000585575ENST00000359692NFIXchr19

13106678

+DNM2chr19

10897240

+
intron-3CDSENST00000585575ENST00000389253NFIXchr19

13106678

+DNM2chr19

10897240

+
intron-3CDSENST00000585575ENST00000355667NFIXchr19

13106678

+DNM2chr19

10897240

+
intron-3CDSENST00000585575ENST00000408974NFIXchr19

13106678

+DNM2chr19

10897240

+
intron-intronENST00000585575ENST00000591819NFIXchr19

13106678

+DNM2chr19

10897240

+
intron-3CDSENST00000360105ENST00000585892NFIXchr19

13106678

+DNM2chr19

10897240

+
intron-3CDSENST00000360105ENST00000314646NFIXchr19

13106678

+DNM2chr19

10897240

+
intron-3CDSENST00000360105ENST00000359692NFIXchr19

13106678

+DNM2chr19

10897240

+
intron-3CDSENST00000360105ENST00000389253NFIXchr19

13106678

+DNM2chr19

10897240

+
intron-3CDSENST00000360105ENST00000355667NFIXchr19

13106678

+DNM2chr19

10897240

+
intron-3CDSENST00000360105ENST00000408974NFIXchr19

13106678

+DNM2chr19

10897240

+
intron-intronENST00000360105ENST00000591819NFIXchr19

13106678

+DNM2chr19

10897240

+
intron-3CDSENST00000588228ENST00000585892NFIXchr19

13106678

+DNM2chr19

10897240

+
intron-3CDSENST00000588228ENST00000314646NFIXchr19

13106678

+DNM2chr19

10897240

+
intron-3CDSENST00000588228ENST00000359692NFIXchr19

13106678

+DNM2chr19

10897240

+
intron-3CDSENST00000588228ENST00000389253NFIXchr19

13106678

+DNM2chr19

10897240

+
intron-3CDSENST00000588228ENST00000355667NFIXchr19

13106678

+DNM2chr19

10897240

+
intron-3CDSENST00000588228ENST00000408974NFIXchr19

13106678

+DNM2chr19

10897240

+
intron-intronENST00000588228ENST00000591819NFIXchr19

13106678

+DNM2chr19

10897240

+
intron-3CDSENST00000587260ENST00000585892NFIXchr19

13106678

+DNM2chr19

10897240

+
intron-3CDSENST00000587260ENST00000314646NFIXchr19

13106678

+DNM2chr19

10897240

+
intron-3CDSENST00000587260ENST00000359692NFIXchr19

13106678

+DNM2chr19

10897240

+
intron-3CDSENST00000587260ENST00000389253NFIXchr19

13106678

+DNM2chr19

10897240

+
intron-3CDSENST00000587260ENST00000355667NFIXchr19

13106678

+DNM2chr19

10897240

+
intron-3CDSENST00000587260ENST00000408974NFIXchr19

13106678

+DNM2chr19

10897240

+
intron-intronENST00000587260ENST00000591819NFIXchr19

13106678

+DNM2chr19

10897240

+
intron-3CDSENST00000358552ENST00000585892NFIXchr19

13106678

+DNM2chr19

10897240

+
intron-3CDSENST00000358552ENST00000314646NFIXchr19

13106678

+DNM2chr19

10897240

+
intron-3CDSENST00000358552ENST00000359692NFIXchr19

13106678

+DNM2chr19

10897240

+
intron-3CDSENST00000358552ENST00000389253NFIXchr19

13106678

+DNM2chr19

10897240

+
intron-3CDSENST00000358552ENST00000355667NFIXchr19

13106678

+DNM2chr19

10897240

+
intron-3CDSENST00000358552ENST00000408974NFIXchr19

13106678

+DNM2chr19

10897240

+
intron-intronENST00000358552ENST00000591819NFIXchr19

13106678

+DNM2chr19

10897240

+
intron-3CDSENST00000588680ENST00000585892NFIXchr19

13106678

+DNM2chr19

10897240

+
intron-3CDSENST00000588680ENST00000314646NFIXchr19

13106678

+DNM2chr19

10897240

+
intron-3CDSENST00000588680ENST00000359692NFIXchr19

13106678

+DNM2chr19

10897240

+
intron-3CDSENST00000588680ENST00000389253NFIXchr19

13106678

+DNM2chr19

10897240

+
intron-3CDSENST00000588680ENST00000355667NFIXchr19

13106678

+DNM2chr19

10897240

+
intron-3CDSENST00000588680ENST00000408974NFIXchr19

13106678

+DNM2chr19

10897240

+
intron-intronENST00000588680ENST00000591819NFIXchr19

13106678

+DNM2chr19

10897240

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000397661NFIXchr1913106678+ENST00000585892DNM2chr1910897240+20182571732017615
ENST00000397661NFIXchr1913106678+ENST00000314646DNM2chr1910897240+28772571732020615
ENST00000397661NFIXchr1913106678+ENST00000359692DNM2chr1910897240+28462571732008611
ENST00000397661NFIXchr1913106678+ENST00000389253DNM2chr1910897240+28772571732020615
ENST00000397661NFIXchr1913106678+ENST00000355667DNM2chr1910897240+28692571732020615
ENST00000397661NFIXchr1913106678+ENST00000408974DNM2chr1910897240+23862571732008611
ENST00000592199NFIXchr1913106678+ENST00000585892DNM2chr1910897240+17882701787595
ENST00000592199NFIXchr1913106678+ENST00000314646DNM2chr1910897240+26472701790596
ENST00000592199NFIXchr1913106678+ENST00000359692DNM2chr1910897240+26162701778592
ENST00000592199NFIXchr1913106678+ENST00000389253DNM2chr1910897240+26472701790596
ENST00000592199NFIXchr1913106678+ENST00000355667DNM2chr1910897240+26392701790596
ENST00000592199NFIXchr1913106678+ENST00000408974DNM2chr1910897240+21562701778592

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000397661ENST00000585892NFIXchr1913106678+DNM2chr1910897240+0.0130702010.9869298
ENST00000397661ENST00000314646NFIXchr1913106678+DNM2chr1910897240+0.0082996210.99170035
ENST00000397661ENST00000359692NFIXchr1913106678+DNM2chr1910897240+0.009797940.9902021
ENST00000397661ENST00000389253NFIXchr1913106678+DNM2chr1910897240+0.0078661420.99213386
ENST00000397661ENST00000355667NFIXchr1913106678+DNM2chr1910897240+0.0082654120.9917346
ENST00000397661ENST00000408974NFIXchr1913106678+DNM2chr1910897240+0.0126910230.98730904
ENST00000592199ENST00000585892NFIXchr1913106678+DNM2chr1910897240+0.0112347040.98876536
ENST00000592199ENST00000314646NFIXchr1913106678+DNM2chr1910897240+0.0070491280.9929509
ENST00000592199ENST00000359692NFIXchr1913106678+DNM2chr1910897240+0.0083164040.9916836
ENST00000592199ENST00000389253NFIXchr1913106678+DNM2chr1910897240+0.0066615250.99333847
ENST00000592199ENST00000355667NFIXchr1913106678+DNM2chr1910897240+0.0068799090.9931201
ENST00000592199ENST00000408974NFIXchr1913106678+DNM2chr1910897240+0.0115880070.98841196

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Fusion Genomic Features for NFIX-DNM2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
NFIXchr1913106678+DNM2chr1910897239+2.00E-141
NFIXchr1913106678+DNM2chr1910897239+2.00E-141
NFIXchr1913106678+DNM2chr1910897239+2.00E-141
NFIXchr1913106678+DNM2chr1910897239+2.00E-141

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for NFIX-DNM2


check button Go to

FGviewer for the breakpoints of chr19:13106678-chr19:10897240

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.DNM2

P50570

FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Plays a role in the regulation of neuron morphology, axon growth and formation of neuronal growth cones (By similarity). Plays an important role in vesicular trafficking processes, in particular endocytosis. Involved in cytokinesis (PubMed:12498685). Regulates maturation of apoptotic cell corpse-containing phagosomes by recruiting PIK3C3 to the phagosome membrane (By similarity). {ECO:0000250|UniProtKB:P39052, ECO:0000250|UniProtKB:P39054, ECO:0000269|PubMed:12498685}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneDNM2chr19:13106678chr19:10897240ENST00000355667521747_866283.0871.0Compositional biasNote=Pro-rich
TgeneDNM2chr19:13106678chr19:10897240ENST00000359692520747_866283.0867.0Compositional biasNote=Pro-rich
TgeneDNM2chr19:13106678chr19:10897240ENST00000389253521747_866283.0871.0Compositional biasNote=Pro-rich
TgeneDNM2chr19:13106678chr19:10897240ENST00000408974520747_866283.0867.0Compositional biasNote=Pro-rich
TgeneDNM2chr19:13106678chr19:10897240ENST00000585892521747_866283.0870.0Compositional biasNote=Pro-rich
TgeneDNM2chr19:13106678chr19:10897240ENST00000355667521519_625283.0871.0DomainPH
TgeneDNM2chr19:13106678chr19:10897240ENST00000355667521653_744283.0871.0DomainGED
TgeneDNM2chr19:13106678chr19:10897240ENST00000359692520519_625283.0867.0DomainPH
TgeneDNM2chr19:13106678chr19:10897240ENST00000359692520653_744283.0867.0DomainGED
TgeneDNM2chr19:13106678chr19:10897240ENST00000389253521519_625283.0871.0DomainPH
TgeneDNM2chr19:13106678chr19:10897240ENST00000389253521653_744283.0871.0DomainGED
TgeneDNM2chr19:13106678chr19:10897240ENST00000408974520519_625283.0867.0DomainPH
TgeneDNM2chr19:13106678chr19:10897240ENST00000408974520653_744283.0867.0DomainGED
TgeneDNM2chr19:13106678chr19:10897240ENST00000585892521519_625283.0870.0DomainPH
TgeneDNM2chr19:13106678chr19:10897240ENST00000585892521653_744283.0870.0DomainGED

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNFIXchr19:13106678chr19:10897240ENST00000397661+1101_1949.0878.6666666666666DNA bindingCTF/NF-I
HgeneNFIXchr19:13106678chr19:10897240ENST00000585575+1111_1940.0495.0DNA bindingCTF/NF-I
HgeneNFIXchr19:13106678chr19:10897240ENST00000587260+191_1940281.6666666666667DNA bindingCTF/NF-I
HgeneNFIXchr19:13106678chr19:10897240ENST00000587760+1101_1940460.6666666666667DNA bindingCTF/NF-I
HgeneNFIXchr19:13106678chr19:10897240ENST00000592199+1111_1949.0503.0DNA bindingCTF/NF-I
HgeneNFIXchr19:13106678chr19:10897240ENST00000397661+110398_4069.0878.6666666666666Motif9aaTAD
HgeneNFIXchr19:13106678chr19:10897240ENST00000585575+111398_4060.0495.0Motif9aaTAD
HgeneNFIXchr19:13106678chr19:10897240ENST00000587260+19398_4060281.6666666666667Motif9aaTAD
HgeneNFIXchr19:13106678chr19:10897240ENST00000587760+110398_4060460.6666666666667Motif9aaTAD
HgeneNFIXchr19:13106678chr19:10897240ENST00000592199+111398_4069.0503.0Motif9aaTAD
TgeneDNM2chr19:13106678chr19:10897240ENST0000035566752128_294283.0871.0DomainDynamin-type G
TgeneDNM2chr19:13106678chr19:10897240ENST0000035969252028_294283.0867.0DomainDynamin-type G
TgeneDNM2chr19:13106678chr19:10897240ENST0000038925352128_294283.0871.0DomainDynamin-type G
TgeneDNM2chr19:13106678chr19:10897240ENST0000040897452028_294283.0867.0DomainDynamin-type G
TgeneDNM2chr19:13106678chr19:10897240ENST0000058589252128_294283.0870.0DomainDynamin-type G
TgeneDNM2chr19:13106678chr19:10897240ENST00000355667521205_211283.0871.0Nucleotide bindingGTP
TgeneDNM2chr19:13106678chr19:10897240ENST00000355667521236_239283.0871.0Nucleotide bindingGTP
TgeneDNM2chr19:13106678chr19:10897240ENST0000035566752138_46283.0871.0Nucleotide bindingGTP
TgeneDNM2chr19:13106678chr19:10897240ENST00000359692520205_211283.0867.0Nucleotide bindingGTP
TgeneDNM2chr19:13106678chr19:10897240ENST00000359692520236_239283.0867.0Nucleotide bindingGTP
TgeneDNM2chr19:13106678chr19:10897240ENST0000035969252038_46283.0867.0Nucleotide bindingGTP
TgeneDNM2chr19:13106678chr19:10897240ENST00000389253521205_211283.0871.0Nucleotide bindingGTP
TgeneDNM2chr19:13106678chr19:10897240ENST00000389253521236_239283.0871.0Nucleotide bindingGTP
TgeneDNM2chr19:13106678chr19:10897240ENST0000038925352138_46283.0871.0Nucleotide bindingGTP
TgeneDNM2chr19:13106678chr19:10897240ENST00000408974520205_211283.0867.0Nucleotide bindingGTP
TgeneDNM2chr19:13106678chr19:10897240ENST00000408974520236_239283.0867.0Nucleotide bindingGTP
TgeneDNM2chr19:13106678chr19:10897240ENST0000040897452038_46283.0867.0Nucleotide bindingGTP
TgeneDNM2chr19:13106678chr19:10897240ENST00000585892521205_211283.0870.0Nucleotide bindingGTP
TgeneDNM2chr19:13106678chr19:10897240ENST00000585892521236_239283.0870.0Nucleotide bindingGTP
TgeneDNM2chr19:13106678chr19:10897240ENST0000058589252138_46283.0870.0Nucleotide bindingGTP
TgeneDNM2chr19:13106678chr19:10897240ENST00000355667521136_139283.0871.0RegionG3 motif
TgeneDNM2chr19:13106678chr19:10897240ENST00000355667521205_208283.0871.0RegionG4 motif
TgeneDNM2chr19:13106678chr19:10897240ENST00000355667521235_238283.0871.0RegionG5 motif
TgeneDNM2chr19:13106678chr19:10897240ENST0000035566752138_45283.0871.0RegionG1 motif
TgeneDNM2chr19:13106678chr19:10897240ENST0000035566752164_66283.0871.0RegionG2 motif
TgeneDNM2chr19:13106678chr19:10897240ENST00000359692520136_139283.0867.0RegionG3 motif
TgeneDNM2chr19:13106678chr19:10897240ENST00000359692520205_208283.0867.0RegionG4 motif
TgeneDNM2chr19:13106678chr19:10897240ENST00000359692520235_238283.0867.0RegionG5 motif
TgeneDNM2chr19:13106678chr19:10897240ENST0000035969252038_45283.0867.0RegionG1 motif
TgeneDNM2chr19:13106678chr19:10897240ENST0000035969252064_66283.0867.0RegionG2 motif
TgeneDNM2chr19:13106678chr19:10897240ENST00000389253521136_139283.0871.0RegionG3 motif
TgeneDNM2chr19:13106678chr19:10897240ENST00000389253521205_208283.0871.0RegionG4 motif
TgeneDNM2chr19:13106678chr19:10897240ENST00000389253521235_238283.0871.0RegionG5 motif
TgeneDNM2chr19:13106678chr19:10897240ENST0000038925352138_45283.0871.0RegionG1 motif
TgeneDNM2chr19:13106678chr19:10897240ENST0000038925352164_66283.0871.0RegionG2 motif
TgeneDNM2chr19:13106678chr19:10897240ENST00000408974520136_139283.0867.0RegionG3 motif
TgeneDNM2chr19:13106678chr19:10897240ENST00000408974520205_208283.0867.0RegionG4 motif
TgeneDNM2chr19:13106678chr19:10897240ENST00000408974520235_238283.0867.0RegionG5 motif
TgeneDNM2chr19:13106678chr19:10897240ENST0000040897452038_45283.0867.0RegionG1 motif
TgeneDNM2chr19:13106678chr19:10897240ENST0000040897452064_66283.0867.0RegionG2 motif
TgeneDNM2chr19:13106678chr19:10897240ENST00000585892521136_139283.0870.0RegionG3 motif
TgeneDNM2chr19:13106678chr19:10897240ENST00000585892521205_208283.0870.0RegionG4 motif
TgeneDNM2chr19:13106678chr19:10897240ENST00000585892521235_238283.0870.0RegionG5 motif
TgeneDNM2chr19:13106678chr19:10897240ENST0000058589252138_45283.0870.0RegionG1 motif
TgeneDNM2chr19:13106678chr19:10897240ENST0000058589252164_66283.0870.0RegionG2 motif


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Fusion Gene Sequence for NFIX-DNM2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000397661_ENST00000585892_TCGA-34-8456-01A_NFIX_chr19_13106678_+_DNM2_chr19_10897240_length(transcript)=2018nt_BP=257nt
GCGAGCGCGGCGGCGGCGGCGGCAGCGGCGGCCCCGGAGCCGGCGGGGCCGAGCTTGCGAGCGGCGAGCGCGGAGCGGCGCCGGGCCGAG
CGCGGGGCCGCGGGCCGGGCGGGCGCAGCGCGGCGGAGGCCGGAGGAGCCGAGCCGGAGCCCGAGCCCGAGCGCGGCCGCCGCCTGCCGG
GCCTCCCCTCGCCGCGGCCGGCCGCCGCGCTCCCGCCCGGGCGCCCAGCTATGTACTCCCCGTACTGCCTCACCCAGCAACTGACCAACC
ACATCCGGGAGTCGCTGCCGGCCCTACGTAGCAAACTACAGAGCCAGCTGCTGTCCCTGGAGAAGGAGGTGGAGGAGTACAAGAACTTTC
GGCCCGACGACCCCACCCGCAAAACCAAAGCCCTGCTGCAGATGGTCCAGCAGTTTGGGGTGGATTTTGAGAAGAGGATCGAGGGCTCAG
GAGATCAGGTGGACACTCTGGAGCTCTCCGGGGGCGCCCGAATCAATCGCATCTTCCACGAGCGGTTCCCATTTGAGCTGGTGAAGATGG
AGTTTGACGAGAAGGACTTACGACGGGAGATCAGCTATGCCATTAAGAACATCCATGGAGTCAGGACCGGGCTTTTCACCCCGGACTTGG
CATTCGAGGCCATTGTGAAAAAGCAGGTCGTCAAGCTGAAAGAGCCCTGTCTGAAATGTGTCGACCTGGTTATCCAGGAGCTAATCAATA
CAGTTAGGCAGTGTACCAGTAAGCTCAGTTCCTACCCCCGGTTGCGAGAGGAGACAGAGCGAATCGTCACCACTTACATCCGGGAACGGG
AGGGGAGAACGAAGGACCAGATTCTTCTGCTGATCGACATTGAGCAGTCCTACATCAACACGAACCATGAGGACTTCATCGGGTTTGCCA
ATGCCCAGCAGAGGAGCACGCAGCTGAACAAGAAGAGAGCCATCCCCAATCAGGGGGAGATCCTGGTGATCCGCAGGGGCTGGCTGACCA
TCAACAACATCAGCCTGATGAAAGGCGGCTCCAAGGAGTACTGGTTTGTGCTGACTGCCGAGTCACTGTCCTGGTACAAGGATGAGGAGG
AGAAAGAGAAGAAGTACATGCTGCCTCTGGACAACCTCAAGATCCGTGATGTGGAGAAGGGCTTCATGTCCAACAAGCACGTCTTCGCCA
TCTTCAACACGGAGCAGAGAAACGTCTACAAGGACCTGCGGCAGATCGAGCTGGCCTGTGACTCCCAGGAAGACGTGGACAGCTGGAAGG
CCTCGTTCCTCCGAGCTGGCGTCTACCCCGAGAAGGACCAGGCAGAAAACGAGGATGGGGCCCAGGAGAACACCTTCTCCATGGACCCCC
AACTGGAGCGGCAGGTGGAGACCATTCGCAACCTGGTGGACTCATACGTGGCCATCATCAACAAGTCCATCCGCGACCTCATGCCAAAGA
CCATCATGCACCTCATGATCAACAATACGAAGGCCTTCATCCACCACGAGCTGCTGGCCTACCTATACTCCTCGGCAGACCAGAGCAGCC
TCATGGAGGAGTCGGCTGACCAGGCACAGCGGCGGGACGACATGCTGCGCATGTACCATGCCCTCAAGGAGGCGCTCAACATCATCGGTG
ACATCAGCACCAGCACTGTGTCCACGCCTGTACCCCCGCCTGTCGATGACACCTGGCTCCAGAGCGCCAGCAGCCACAGCCCCACTCCAC
AGCGCCGACCGGTGTCCAGCATACACCCCCCTGGCCGGCCCCCAGCAGTGAGGGGCCCCACTCCAGGGCCCCCCCTGATTCCTGTTCCCG
TGGGGGCAGCAGCCTCCTTCTCGGCGCCCCCAATCCCATCCCGGCCTGGACCCCAGAGCGTGTTTGCCAACAGTGACCTCTTCCCAGCCC
CGCCTCAGATCCCATCTCGGCCAGTTCGGATCCCCCCAGGGATTCCCCCAGGAGTGCCCAGAAGACCCCCTGCTGCGCCCAGCCGGCCCA

>In-frame_ENST00000397661_ENST00000585892_TCGA-34-8456-01A_NFIX_chr19_13106678_+_DNM2_chr19_10897240_length(amino acids)=615AA_start in transcript=173_stop in transcript=2017
MPGLPSPRPAAALPPGRPAMYSPYCLTQQLTNHIRESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIE
GSGDQVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAFEAIVKKQVVKLKEPCLKCVDLVIQEL
INTVRQCTSKLSSYPRLREETERIVTTYIREREGRTKDQILLLIDIEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQGEILVIRRGW
LTINNISLMKGGSKEYWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIELACDSQEDVDS
WKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQ
SSLMEESADQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAVRGPTPGPPLIP

--------------------------------------------------------------
>In-frame_ENST00000397661_ENST00000314646_TCGA-34-8456-01A_NFIX_chr19_13106678_+_DNM2_chr19_10897240_length(transcript)=2877nt_BP=257nt
GCGAGCGCGGCGGCGGCGGCGGCAGCGGCGGCCCCGGAGCCGGCGGGGCCGAGCTTGCGAGCGGCGAGCGCGGAGCGGCGCCGGGCCGAG
CGCGGGGCCGCGGGCCGGGCGGGCGCAGCGCGGCGGAGGCCGGAGGAGCCGAGCCGGAGCCCGAGCCCGAGCGCGGCCGCCGCCTGCCGG
GCCTCCCCTCGCCGCGGCCGGCCGCCGCGCTCCCGCCCGGGCGCCCAGCTATGTACTCCCCGTACTGCCTCACCCAGCAACTGACCAACC
ACATCCGGGAGTCGCTGCCGGCCCTACGTAGCAAACTACAGAGCCAGCTGCTGTCCCTGGAGAAGGAGGTGGAGGAGTACAAGAACTTTC
GGCCCGACGACCCCACCCGCAAAACCAAAGCCCTGCTGCAGATGGTCCAGCAGTTTGGGGTGGATTTTGAGAAGAGGATCGAGGGCTCAG
GAGATCAGGTGGACACTCTGGAGCTCTCCGGGGGCGCCCGAATCAATCGCATCTTCCACGAGCGGTTCCCATTTGAGCTGGTGAAGATGG
AGTTTGACGAGAAGGACTTACGACGGGAGATCAGCTATGCCATTAAGAACATCCATGGAGTCAGGACGGGGCTCTTCACCCCCGACATGG
CCTTTGAAGCCATTGTGAAAAAACAGATTGTAAAACTCAAAGAGCCGAGTTTGAAGTGTGTTGATCTCGTGGTCTCAGAGCTGGCCACGG
TCATAAAAAAGTGTGCCGAGAAGCTCAGTTCCTACCCCCGGTTGCGAGAGGAGACAGAGCGAATCGTCACCACTTACATCCGGGAACGGG
AGGGGAGAACGAAGGACCAGATTCTTCTGCTGATCGACATTGAGCAGTCCTACATCAACACGAACCATGAGGACTTCATCGGGTTTGCCA
ATGCCCAGCAGAGGAGCACGCAGCTGAACAAGAAGAGAGCCATCCCCAATCAGCCTGAAACCCTGGTGATCCGCAGGGGCTGGCTGACCA
TCAACAACATCAGCCTGATGAAAGGCGGCTCCAAGGAGTACTGGTTTGTGCTGACTGCCGAGTCACTGTCCTGGTACAAGGATGAGGAGG
AGAAAGAGAAGAAGTACATGCTGCCTCTGGACAACCTCAAGATCCGTGATGTGGAGAAGGGCTTCATGTCCAACAAGCACGTCTTCGCCA
TCTTCAACACGGAGCAGAGAAACGTCTACAAGGACCTGCGGCAGATCGAGCTGGCCTGTGACTCCCAGGAAGACGTGGACAGCTGGAAGG
CCTCGTTCCTCCGAGCTGGCGTCTACCCCGAGAAGGACCAGGCAGAAAACGAGGATGGGGCCCAGGAGAACACCTTCTCCATGGACCCCC
AACTGGAGCGGCAGGTGGAGACCATTCGCAACCTGGTGGACTCATACGTGGCCATCATCAACAAGTCCATCCGCGACCTCATGCCAAAGA
CCATCATGCACCTCATGATCAACAATACGAAGGCCTTCATCCACCACGAGCTGCTGGCCTACCTATACTCCTCGGCAGACCAGAGCAGCC
TCATGGAGGAGTCGGCTGACCAGGCACAGCGGCGGGACGACATGCTGCGCATGTACCATGCCCTCAAGGAGGCGCTCAACATCATCGGTG
ACATCAGCACCAGCACTGTGTCCACGCCTGTACCCCCGCCTGTCGATGACACCTGGCTCCAGAGCGCCAGCAGCCACAGCCCCACTCCAC
AGCGCCGACCGGTGTCCAGCATACACCCCCCTGGCCGGCCCCCAGCAGTGAGGGGCCCCACTCCAGGGCCCCCCCTGATTCCTGTTCCCG
TGGGGGCAGCAGCCTCCTTCTCGGCGCCCCCAATCCCATCCCGGCCTGGACCCCAGAGCGTGTTTGCCAACAGTGACCTCTTCCCAGCCC
CGCCTCAGATCCCATCTCGGCCAGTTCGGATCCCCCCAGGGATTCCCCCAGGAGTGCCCAGCAGAAGACCCCCTGCTGCGCCCAGCCGGC
CCACCATTATCCGCCCAGCCGAGCCATCCCTGCTCGACTAGGCCTCGAGGGGGGCGTGCTCTCGGGGGGGCCTCACGCACCCGCGGCGCA
GGAGCTTCAGTGGTCTGGGGCCCTCCGCCGCCCCTATGCTGGGACCAGGCTCCCAGTGGGCAGCCCTGGCCTCTTCCTTAACGCTGGCCC
CGGTCCAGGGCCGGCCCCTGTGCCTGGCTGGACACCGCACTGCGCAAAGGGGCCCTGGAGCTCCAGGCAGGGGGCGCTGGGGTGTTGCAC
TTTGGGGGATGGAGTCTCAGGGTGGCAGAGGGGGGACCAGAACCCTTGACACCATCCTGAATGAGGGGTCCAGCCTGGGGGGGACTCTAC
CAAGGTCTTCTTGGGCTGGGAAAGCCCATGTAGGGCAGGCCTTCTATAAGTGCGGGCACCAAGGGCGCCTACATCCCCAGGCCTTGCTGG
GGTGCAGGGGTATATCAACTTCCCATTAGCAGGAGCTCCCCAGCGGCAAGCCTGGCCCAGTGGGCTCGGTAGTGCCCAGCTGGCAGGCCT
GAGGTGTACATAGTCCTTCCCGGCCATATTAACCACACAGCCTGAGCCTGGCCCAGCCTCGGCTGCCAGAGGTGCCTTTGCTAGGCCCGG
AGCCGTTGGCCCGGGCCGGCCTTGCCCTATTCCTCTCCTCCTCCTCCTCCTGGGTCCCCCAGGGTGGCTGGGCTTGGGCTATGTGGGTGG
TGGTGGCGGGGGGTCTTGGGGGCCTCTCAGCTCCCGCCCATGCCTCCCTGATGGGTGGGCCCAGGGCGGCCTCTCTCTGAGGAGACCTCA

>In-frame_ENST00000397661_ENST00000314646_TCGA-34-8456-01A_NFIX_chr19_13106678_+_DNM2_chr19_10897240_length(amino acids)=615AA_start in transcript=173_stop in transcript=2020
MPGLPSPRPAAALPPGRPAMYSPYCLTQQLTNHIRESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIE
GSGDQVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDMAFEAIVKKQIVKLKEPSLKCVDLVVSEL
ATVIKKCAEKLSSYPRLREETERIVTTYIREREGRTKDQILLLIDIEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQPETLVIRRGW
LTINNISLMKGGSKEYWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIELACDSQEDVDS
WKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQ
SSLMEESADQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAVRGPTPGPPLIP

--------------------------------------------------------------
>In-frame_ENST00000397661_ENST00000359692_TCGA-34-8456-01A_NFIX_chr19_13106678_+_DNM2_chr19_10897240_length(transcript)=2846nt_BP=257nt
GCGAGCGCGGCGGCGGCGGCGGCAGCGGCGGCCCCGGAGCCGGCGGGGCCGAGCTTGCGAGCGGCGAGCGCGGAGCGGCGCCGGGCCGAG
CGCGGGGCCGCGGGCCGGGCGGGCGCAGCGCGGCGGAGGCCGGAGGAGCCGAGCCGGAGCCCGAGCCCGAGCGCGGCCGCCGCCTGCCGG
GCCTCCCCTCGCCGCGGCCGGCCGCCGCGCTCCCGCCCGGGCGCCCAGCTATGTACTCCCCGTACTGCCTCACCCAGCAACTGACCAACC
ACATCCGGGAGTCGCTGCCGGCCCTACGTAGCAAACTACAGAGCCAGCTGCTGTCCCTGGAGAAGGAGGTGGAGGAGTACAAGAACTTTC
GGCCCGACGACCCCACCCGCAAAACCAAAGCCCTGCTGCAGATGGTCCAGCAGTTTGGGGTGGATTTTGAGAAGAGGATCGAGGGCTCAG
GAGATCAGGTGGACACTCTGGAGCTCTCCGGGGGCGCCCGAATCAATCGCATCTTCCACGAGCGGTTCCCATTTGAGCTGGTGAAGATGG
AGTTTGACGAGAAGGACTTACGACGGGAGATCAGCTATGCCATTAAGAACATCCATGGAGTCAGGACCGGGCTTTTCACCCCGGACTTGG
CATTCGAGGCCATTGTGAAAAAGCAGGTCGTCAAGCTGAAAGAGCCCTGTCTGAAATGTGTCGACCTGGTTATCCAGGAGCTAATCAATA
CAGTTAGGCAGTGTACCAGTAAGCTCAGTTCCTACCCCCGGTTGCGAGAGGAGACAGAGCGAATCGTCACCACTTACATCCGGGAACGGG
AGGGGAGAACGAAGGACCAGATTCTTCTGCTGATCGACATTGAGCAGTCCTACATCAACACGAACCATGAGGACTTCATCGGGTTTGCCA
ATGCCCAGCAGAGGAGCACGCAGCTGAACAAGAAGAGAGCCATCCCCAATCAGGTGATCCGCAGGGGCTGGCTGACCATCAACAACATCA
GCCTGATGAAAGGCGGCTCCAAGGAGTACTGGTTTGTGCTGACTGCCGAGTCACTGTCCTGGTACAAGGATGAGGAGGAGAAAGAGAAGA
AGTACATGCTGCCTCTGGACAACCTCAAGATCCGTGATGTGGAGAAGGGCTTCATGTCCAACAAGCACGTCTTCGCCATCTTCAACACGG
AGCAGAGAAACGTCTACAAGGACCTGCGGCAGATCGAGCTGGCCTGTGACTCCCAGGAAGACGTGGACAGCTGGAAGGCCTCGTTCCTCC
GAGCTGGCGTCTACCCCGAGAAGGACCAGGCAGAAAACGAGGATGGGGCCCAGGAGAACACCTTCTCCATGGACCCCCAACTGGAGCGGC
AGGTGGAGACCATTCGCAACCTGGTGGACTCATACGTGGCCATCATCAACAAGTCCATCCGCGACCTCATGCCAAAGACCATCATGCACC
TCATGATCAACAATACGAAGGCCTTCATCCACCACGAGCTGCTGGCCTACCTATACTCCTCGGCAGACCAGAGCAGCCTCATGGAGGAGT
CGGCTGACCAGGCACAGCGGCGGGACGACATGCTGCGCATGTACCATGCCCTCAAGGAGGCGCTCAACATCATCGGTGACATCAGCACCA
GCACTGTGTCCACGCCTGTACCCCCGCCTGTCGATGACACCTGGCTCCAGAGCGCCAGCAGCCACAGCCCCACTCCACAGCGCCGACCGG
TGTCCAGCATACACCCCCCTGGCCGGCCCCCAGCAGTGAGGGGCCCCACTCCAGGGCCCCCCCTGATTCCTGTTCCCGTGGGGGCAGCAG
CCTCCTTCTCGGCGCCCCCAATCCCATCCCGGCCTGGACCCCAGAGCGTGTTTGCCAACAGTGACCTCTTCCCAGCCCCGCCTCAGATCC
CATCTCGGCCAGTTCGGATCCCCCCAGGGATTCCCCCAGGAGTGCCCAGCAGAAGACCCCCTGCTGCGCCCAGCCGGCCCACCATTATCC
GCCCAGCCGAGCCATCCCTGCTCGACTAGGCCTCGAGGGGGGCGTGCTCTCGGGGGGGCCTCACGCACCCGCGGCGCAGGAGCTTCAGTG
GTCTGGGGCCCTCCGCCGCCCCTATGCTGGGACCAGGCTCCCAGTGGGCAGCCCTGGCCTCTTCCTTAACGCTGGCCCCGGTCCAGGGCC
GGCCCCTGTGCCTGGCTGGACACCGCACTGCGCAAAGGGGCCCTGGAGCTCCAGGCAGGGGGCGCTGGGGTGTTGCACTTTGGGGGATGG
AGTCTCAGGGTGGCAGAGGGGGGACCAGAACCCTTGACACCATCCTGAATGAGGGGTCCAGCCTGGGGGGGACTCTACCAAGGTCTTCTT
GGGCTGGGAAAGCCCATGTAGGGCAGGCCTTCTATAAGTGCGGGCACCAAGGGCGCCTACATCCCCAGGCCTTGCTGGGGTGCAGGGGTA
TATCAACTTCCCATTAGCAGGAGCTCCCCAGCGGCAAGCCTGGCCCAGTGGGCTCGGTAGTGCCCAGCTGGCAGGCCTGAGGTGTACATA
GTCCTTCCCGGCCATATTAACCACACAGCCTGAGCCTGGCCCAGCCTCGGCTGCCAGAGGTGCCTTTGCTAGGCCCGGAGCCGTTGGCCC
GGGCCGGCCTTGCCCTATTCCTCTCCTCCTCCTCCTCCTGGGTCCCCCAGGGTGGCTGGGCTTGGGCTATGTGGGTGGTGGTGGCGGGGG
GTCTTGGGGGCCTCTCAGCTCCCGCCCATGCCTCCCTGATGGGTGGGCCCAGGGCGGCCTCTCTCTGAGGAGACCTCACCCACTCCTCGC

>In-frame_ENST00000397661_ENST00000359692_TCGA-34-8456-01A_NFIX_chr19_13106678_+_DNM2_chr19_10897240_length(amino acids)=611AA_start in transcript=173_stop in transcript=2008
MPGLPSPRPAAALPPGRPAMYSPYCLTQQLTNHIRESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIE
GSGDQVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAFEAIVKKQVVKLKEPCLKCVDLVIQEL
INTVRQCTSKLSSYPRLREETERIVTTYIREREGRTKDQILLLIDIEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQVIRRGWLTIN
NISLMKGGSKEYWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIELACDSQEDVDSWKAS
FLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLM
EESADQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAVRGPTPGPPLIPVPVG

--------------------------------------------------------------
>In-frame_ENST00000397661_ENST00000389253_TCGA-34-8456-01A_NFIX_chr19_13106678_+_DNM2_chr19_10897240_length(transcript)=2877nt_BP=257nt
GCGAGCGCGGCGGCGGCGGCGGCAGCGGCGGCCCCGGAGCCGGCGGGGCCGAGCTTGCGAGCGGCGAGCGCGGAGCGGCGCCGGGCCGAG
CGCGGGGCCGCGGGCCGGGCGGGCGCAGCGCGGCGGAGGCCGGAGGAGCCGAGCCGGAGCCCGAGCCCGAGCGCGGCCGCCGCCTGCCGG
GCCTCCCCTCGCCGCGGCCGGCCGCCGCGCTCCCGCCCGGGCGCCCAGCTATGTACTCCCCGTACTGCCTCACCCAGCAACTGACCAACC
ACATCCGGGAGTCGCTGCCGGCCCTACGTAGCAAACTACAGAGCCAGCTGCTGTCCCTGGAGAAGGAGGTGGAGGAGTACAAGAACTTTC
GGCCCGACGACCCCACCCGCAAAACCAAAGCCCTGCTGCAGATGGTCCAGCAGTTTGGGGTGGATTTTGAGAAGAGGATCGAGGGCTCAG
GAGATCAGGTGGACACTCTGGAGCTCTCCGGGGGCGCCCGAATCAATCGCATCTTCCACGAGCGGTTCCCATTTGAGCTGGTGAAGATGG
AGTTTGACGAGAAGGACTTACGACGGGAGATCAGCTATGCCATTAAGAACATCCATGGAGTCAGGACGGGGCTCTTCACCCCCGACATGG
CCTTTGAAGCCATTGTGAAAAAACAGATTGTAAAACTCAAAGAGCCGAGTTTGAAGTGTGTTGATCTCGTGGTCTCAGAGCTGGCCACGG
TCATAAAAAAGTGTGCCGAGAAGCTCAGTTCCTACCCCCGGTTGCGAGAGGAGACAGAGCGAATCGTCACCACTTACATCCGGGAACGGG
AGGGGAGAACGAAGGACCAGATTCTTCTGCTGATCGACATTGAGCAGTCCTACATCAACACGAACCATGAGGACTTCATCGGGTTTGCCA
ATGCCCAGCAGAGGAGCACGCAGCTGAACAAGAAGAGAGCCATCCCCAATCAGGGGGAGATCCTGGTGATCCGCAGGGGCTGGCTGACCA
TCAACAACATCAGCCTGATGAAAGGCGGCTCCAAGGAGTACTGGTTTGTGCTGACTGCCGAGTCACTGTCCTGGTACAAGGATGAGGAGG
AGAAAGAGAAGAAGTACATGCTGCCTCTGGACAACCTCAAGATCCGTGATGTGGAGAAGGGCTTCATGTCCAACAAGCACGTCTTCGCCA
TCTTCAACACGGAGCAGAGAAACGTCTACAAGGACCTGCGGCAGATCGAGCTGGCCTGTGACTCCCAGGAAGACGTGGACAGCTGGAAGG
CCTCGTTCCTCCGAGCTGGCGTCTACCCCGAGAAGGACCAGGCAGAAAACGAGGATGGGGCCCAGGAGAACACCTTCTCCATGGACCCCC
AACTGGAGCGGCAGGTGGAGACCATTCGCAACCTGGTGGACTCATACGTGGCCATCATCAACAAGTCCATCCGCGACCTCATGCCAAAGA
CCATCATGCACCTCATGATCAACAATACGAAGGCCTTCATCCACCACGAGCTGCTGGCCTACCTATACTCCTCGGCAGACCAGAGCAGCC
TCATGGAGGAGTCGGCTGACCAGGCACAGCGGCGGGACGACATGCTGCGCATGTACCATGCCCTCAAGGAGGCGCTCAACATCATCGGTG
ACATCAGCACCAGCACTGTGTCCACGCCTGTACCCCCGCCTGTCGATGACACCTGGCTCCAGAGCGCCAGCAGCCACAGCCCCACTCCAC
AGCGCCGACCGGTGTCCAGCATACACCCCCCTGGCCGGCCCCCAGCAGTGAGGGGCCCCACTCCAGGGCCCCCCCTGATTCCTGTTCCCG
TGGGGGCAGCAGCCTCCTTCTCGGCGCCCCCAATCCCATCCCGGCCTGGACCCCAGAGCGTGTTTGCCAACAGTGACCTCTTCCCAGCCC
CGCCTCAGATCCCATCTCGGCCAGTTCGGATCCCCCCAGGGATTCCCCCAGGAGTGCCCAGCAGAAGACCCCCTGCTGCGCCCAGCCGGC
CCACCATTATCCGCCCAGCCGAGCCATCCCTGCTCGACTAGGCCTCGAGGGGGGCGTGCTCTCGGGGGGGCCTCACGCACCCGCGGCGCA
GGAGCTTCAGTGGTCTGGGGCCCTCCGCCGCCCCTATGCTGGGACCAGGCTCCCAGTGGGCAGCCCTGGCCTCTTCCTTAACGCTGGCCC
CGGTCCAGGGCCGGCCCCTGTGCCTGGCTGGACACCGCACTGCGCAAAGGGGCCCTGGAGCTCCAGGCAGGGGGCGCTGGGGTGTTGCAC
TTTGGGGGATGGAGTCTCAGGGTGGCAGAGGGGGGACCAGAACCCTTGACACCATCCTGAATGAGGGGTCCAGCCTGGGGGGGACTCTAC
CAAGGTCTTCTTGGGCTGGGAAAGCCCATGTAGGGCAGGCCTTCTATAAGTGCGGGCACCAAGGGCGCCTACATCCCCAGGCCTTGCTGG
GGTGCAGGGGTATATCAACTTCCCATTAGCAGGAGCTCCCCAGCGGCAAGCCTGGCCCAGTGGGCTCGGTAGTGCCCAGCTGGCAGGCCT
GAGGTGTACATAGTCCTTCCCGGCCATATTAACCACACAGCCTGAGCCTGGCCCAGCCTCGGCTGCCAGAGGTGCCTTTGCTAGGCCCGG
AGCCGTTGGCCCGGGCCGGCCTTGCCCTATTCCTCTCCTCCTCCTCCTCCTGGGTCCCCCAGGGTGGCTGGGCTTGGGCTATGTGGGTGG
TGGTGGCGGGGGGTCTTGGGGGCCTCTCAGCTCCCGCCCATGCCTCCCTGATGGGTGGGCCCAGGGCGGCCTCTCTCTGAGGAGACCTCA

>In-frame_ENST00000397661_ENST00000389253_TCGA-34-8456-01A_NFIX_chr19_13106678_+_DNM2_chr19_10897240_length(amino acids)=615AA_start in transcript=173_stop in transcript=2020
MPGLPSPRPAAALPPGRPAMYSPYCLTQQLTNHIRESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIE
GSGDQVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDMAFEAIVKKQIVKLKEPSLKCVDLVVSEL
ATVIKKCAEKLSSYPRLREETERIVTTYIREREGRTKDQILLLIDIEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQGEILVIRRGW
LTINNISLMKGGSKEYWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIELACDSQEDVDS
WKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQ
SSLMEESADQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAVRGPTPGPPLIP

--------------------------------------------------------------
>In-frame_ENST00000397661_ENST00000355667_TCGA-34-8456-01A_NFIX_chr19_13106678_+_DNM2_chr19_10897240_length(transcript)=2869nt_BP=257nt
GCGAGCGCGGCGGCGGCGGCGGCAGCGGCGGCCCCGGAGCCGGCGGGGCCGAGCTTGCGAGCGGCGAGCGCGGAGCGGCGCCGGGCCGAG
CGCGGGGCCGCGGGCCGGGCGGGCGCAGCGCGGCGGAGGCCGGAGGAGCCGAGCCGGAGCCCGAGCCCGAGCGCGGCCGCCGCCTGCCGG
GCCTCCCCTCGCCGCGGCCGGCCGCCGCGCTCCCGCCCGGGCGCCCAGCTATGTACTCCCCGTACTGCCTCACCCAGCAACTGACCAACC
ACATCCGGGAGTCGCTGCCGGCCCTACGTAGCAAACTACAGAGCCAGCTGCTGTCCCTGGAGAAGGAGGTGGAGGAGTACAAGAACTTTC
GGCCCGACGACCCCACCCGCAAAACCAAAGCCCTGCTGCAGATGGTCCAGCAGTTTGGGGTGGATTTTGAGAAGAGGATCGAGGGCTCAG
GAGATCAGGTGGACACTCTGGAGCTCTCCGGGGGCGCCCGAATCAATCGCATCTTCCACGAGCGGTTCCCATTTGAGCTGGTGAAGATGG
AGTTTGACGAGAAGGACTTACGACGGGAGATCAGCTATGCCATTAAGAACATCCATGGAGTCAGGACCGGGCTTTTCACCCCGGACTTGG
CATTCGAGGCCATTGTGAAAAAGCAGGTCGTCAAGCTGAAAGAGCCCTGTCTGAAATGTGTCGACCTGGTTATCCAGGAGCTAATCAATA
CAGTTAGGCAGTGTACCAGTAAGCTCAGTTCCTACCCCCGGTTGCGAGAGGAGACAGAGCGAATCGTCACCACTTACATCCGGGAACGGG
AGGGGAGAACGAAGGACCAGATTCTTCTGCTGATCGACATTGAGCAGTCCTACATCAACACGAACCATGAGGACTTCATCGGGTTTGCCA
ATGCCCAGCAGAGGAGCACGCAGCTGAACAAGAAGAGAGCCATCCCCAATCAGGGGGAGATCCTGGTGATCCGCAGGGGCTGGCTGACCA
TCAACAACATCAGCCTGATGAAAGGCGGCTCCAAGGAGTACTGGTTTGTGCTGACTGCCGAGTCACTGTCCTGGTACAAGGATGAGGAGG
AGAAAGAGAAGAAGTACATGCTGCCTCTGGACAACCTCAAGATCCGTGATGTGGAGAAGGGCTTCATGTCCAACAAGCACGTCTTCGCCA
TCTTCAACACGGAGCAGAGAAACGTCTACAAGGACCTGCGGCAGATCGAGCTGGCCTGTGACTCCCAGGAAGACGTGGACAGCTGGAAGG
CCTCGTTCCTCCGAGCTGGCGTCTACCCCGAGAAGGACCAGGCAGAAAACGAGGATGGGGCCCAGGAGAACACCTTCTCCATGGACCCCC
AACTGGAGCGGCAGGTGGAGACCATTCGCAACCTGGTGGACTCATACGTGGCCATCATCAACAAGTCCATCCGCGACCTCATGCCAAAGA
CCATCATGCACCTCATGATCAACAATACGAAGGCCTTCATCCACCACGAGCTGCTGGCCTACCTATACTCCTCGGCAGACCAGAGCAGCC
TCATGGAGGAGTCGGCTGACCAGGCACAGCGGCGGGACGACATGCTGCGCATGTACCATGCCCTCAAGGAGGCGCTCAACATCATCGGTG
ACATCAGCACCAGCACTGTGTCCACGCCTGTACCCCCGCCTGTCGATGACACCTGGCTCCAGAGCGCCAGCAGCCACAGCCCCACTCCAC
AGCGCCGACCGGTGTCCAGCATACACCCCCCTGGCCGGCCCCCAGCAGTGAGGGGCCCCACTCCAGGGCCCCCCCTGATTCCTGTTCCCG
TGGGGGCAGCAGCCTCCTTCTCGGCGCCCCCAATCCCATCCCGGCCTGGACCCCAGAGCGTGTTTGCCAACAGTGACCTCTTCCCAGCCC
CGCCTCAGATCCCATCTCGGCCAGTTCGGATCCCCCCAGGGATTCCCCCAGGAGTGCCCAGCAGAAGACCCCCTGCTGCGCCCAGCCGGC
CCACCATTATCCGCCCAGCCGAGCCATCCCTGCTCGACTAGGCCTCGAGGGGGGCGTGCTCTCGGGGGGGCCTCACGCACCCGCGGCGCA
GGAGCTTCAGTGGTCTGGGGCCCTCCGCCGCCCCTATGCTGGGACCAGGCTCCCAGTGGGCAGCCCTGGCCTCTTCCTTAACGCTGGCCC
CGGTCCAGGGCCGGCCCCTGTGCCTGGCTGGACACCGCACTGCGCAAAGGGGCCCTGGAGCTCCAGGCAGGGGGCGCTGGGGTGTTGCAC
TTTGGGGGATGGAGTCTCAGGGTGGCAGAGGGGGGACCAGAACCCTTGACACCATCCTGAATGAGGGGTCCAGCCTGGGGGGGACTCTAC
CAAGGTCTTCTTGGGCTGGGAAAGCCCATGTAGGGCAGGCCTTCTATAAGTGCGGGCACCAAGGGCGCCTACATCCCCAGGCCTTGCTGG
GGTGCAGGGGTATATCAACTTCCCATTAGCAGGAGCTCCCCAGCGGCAAGCCTGGCCCAGTGGGCTCGGTAGTGCCCAGCTGGCAGGCCT
GAGGTGTACATAGTCCTTCCCGGCCATATTAACCACACAGCCTGAGCCTGGCCCAGCCTCGGCTGCCAGAGGTGCCTTTGCTAGGCCCGG
AGCCGTTGGCCCGGGCCGGCCTTGCCCTATTCCTCTCCTCCTCCTCCTCCTGGGTCCCCCAGGGTGGCTGGGCTTGGGCTATGTGGGTGG
TGGTGGCGGGGGGTCTTGGGGGCCTCTCAGCTCCCGCCCATGCCTCCCTGATGGGTGGGCCCAGGGCGGCCTCTCTCTGAGGAGACCTCA

>In-frame_ENST00000397661_ENST00000355667_TCGA-34-8456-01A_NFIX_chr19_13106678_+_DNM2_chr19_10897240_length(amino acids)=615AA_start in transcript=173_stop in transcript=2020
MPGLPSPRPAAALPPGRPAMYSPYCLTQQLTNHIRESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIE
GSGDQVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAFEAIVKKQVVKLKEPCLKCVDLVIQEL
INTVRQCTSKLSSYPRLREETERIVTTYIREREGRTKDQILLLIDIEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQGEILVIRRGW
LTINNISLMKGGSKEYWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIELACDSQEDVDS
WKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQ
SSLMEESADQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAVRGPTPGPPLIP

--------------------------------------------------------------
>In-frame_ENST00000397661_ENST00000408974_TCGA-34-8456-01A_NFIX_chr19_13106678_+_DNM2_chr19_10897240_length(transcript)=2386nt_BP=257nt
GCGAGCGCGGCGGCGGCGGCGGCAGCGGCGGCCCCGGAGCCGGCGGGGCCGAGCTTGCGAGCGGCGAGCGCGGAGCGGCGCCGGGCCGAG
CGCGGGGCCGCGGGCCGGGCGGGCGCAGCGCGGCGGAGGCCGGAGGAGCCGAGCCGGAGCCCGAGCCCGAGCGCGGCCGCCGCCTGCCGG
GCCTCCCCTCGCCGCGGCCGGCCGCCGCGCTCCCGCCCGGGCGCCCAGCTATGTACTCCCCGTACTGCCTCACCCAGCAACTGACCAACC
ACATCCGGGAGTCGCTGCCGGCCCTACGTAGCAAACTACAGAGCCAGCTGCTGTCCCTGGAGAAGGAGGTGGAGGAGTACAAGAACTTTC
GGCCCGACGACCCCACCCGCAAAACCAAAGCCCTGCTGCAGATGGTCCAGCAGTTTGGGGTGGATTTTGAGAAGAGGATCGAGGGCTCAG
GAGATCAGGTGGACACTCTGGAGCTCTCCGGGGGCGCCCGAATCAATCGCATCTTCCACGAGCGGTTCCCATTTGAGCTGGTGAAGATGG
AGTTTGACGAGAAGGACTTACGACGGGAGATCAGCTATGCCATTAAGAACATCCATGGAGTCAGGACGGGGCTCTTCACCCCCGACATGG
CCTTTGAAGCCATTGTGAAAAAACAGATTGTAAAACTCAAAGAGCCGAGTTTGAAGTGTGTTGATCTCGTGGTCTCAGAGCTGGCCACGG
TCATAAAAAAGTGTGCCGAGAAGCTCAGTTCCTACCCCCGGTTGCGAGAGGAGACAGAGCGAATCGTCACCACTTACATCCGGGAACGGG
AGGGGAGAACGAAGGACCAGATTCTTCTGCTGATCGACATTGAGCAGTCCTACATCAACACGAACCATGAGGACTTCATCGGGTTTGCCA
ATGCCCAGCAGAGGAGCACGCAGCTGAACAAGAAGAGAGCCATCCCCAATCAGGTGATCCGCAGGGGCTGGCTGACCATCAACAACATCA
GCCTGATGAAAGGCGGCTCCAAGGAGTACTGGTTTGTGCTGACTGCCGAGTCACTGTCCTGGTACAAGGATGAGGAGGAGAAAGAGAAGA
AGTACATGCTGCCTCTGGACAACCTCAAGATCCGTGATGTGGAGAAGGGCTTCATGTCCAACAAGCACGTCTTCGCCATCTTCAACACGG
AGCAGAGAAACGTCTACAAGGACCTGCGGCAGATCGAGCTGGCCTGTGACTCCCAGGAAGACGTGGACAGCTGGAAGGCCTCGTTCCTCC
GAGCTGGCGTCTACCCCGAGAAGGACCAGGCAGAAAACGAGGATGGGGCCCAGGAGAACACCTTCTCCATGGACCCCCAACTGGAGCGGC
AGGTGGAGACCATTCGCAACCTGGTGGACTCATACGTGGCCATCATCAACAAGTCCATCCGCGACCTCATGCCAAAGACCATCATGCACC
TCATGATCAACAATACGAAGGCCTTCATCCACCACGAGCTGCTGGCCTACCTATACTCCTCGGCAGACCAGAGCAGCCTCATGGAGGAGT
CGGCTGACCAGGCACAGCGGCGGGACGACATGCTGCGCATGTACCATGCCCTCAAGGAGGCGCTCAACATCATCGGTGACATCAGCACCA
GCACTGTGTCCACGCCTGTACCCCCGCCTGTCGATGACACCTGGCTCCAGAGCGCCAGCAGCCACAGCCCCACTCCACAGCGCCGACCGG
TGTCCAGCATACACCCCCCTGGCCGGCCCCCAGCAGTGAGGGGCCCCACTCCAGGGCCCCCCCTGATTCCTGTTCCCGTGGGGGCAGCAG
CCTCCTTCTCGGCGCCCCCAATCCCATCCCGGCCTGGACCCCAGAGCGTGTTTGCCAACAGTGACCTCTTCCCAGCCCCGCCTCAGATCC
CATCTCGGCCAGTTCGGATCCCCCCAGGGATTCCCCCAGGAGTGCCCAGCAGAAGACCCCCTGCTGCGCCCAGCCGGCCCACCATTATCC
GCCCAGCCGAGCCATCCCTGCTCGACTAGGCCTCGAGGGGGGCGTGCTCTCGGGGGGGCCTCACGCACCCGCGGCGCAGGAGCTTCAGTG
GTCTGGGGCCCTCCGCCGCCCCTATGCTGGGACCAGGCTCCCAGTGGGCAGCCCTGGCCTCTTCCTTAACGCTGGCCCCGGTCCAGGGCC
GGCCCCTGTGCCTGGCTGGACACCGCACTGCGCAAAGGGGCCCTGGAGCTCCAGGCAGGGGGCGCTGGGGTGTTGCACTTTGGGGGATGG
AGTCTCAGGGTGGCAGAGGGGGGACCAGAACCCTTGACACCATCCTGAATGAGGGGTCCAGCCTGGGGGGGACTCTACCAAGGTCTTCTT

>In-frame_ENST00000397661_ENST00000408974_TCGA-34-8456-01A_NFIX_chr19_13106678_+_DNM2_chr19_10897240_length(amino acids)=611AA_start in transcript=173_stop in transcript=2008
MPGLPSPRPAAALPPGRPAMYSPYCLTQQLTNHIRESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIE
GSGDQVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDMAFEAIVKKQIVKLKEPSLKCVDLVVSEL
ATVIKKCAEKLSSYPRLREETERIVTTYIREREGRTKDQILLLIDIEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQVIRRGWLTIN
NISLMKGGSKEYWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIELACDSQEDVDSWKAS
FLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLM
EESADQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAVRGPTPGPPLIPVPVG

--------------------------------------------------------------
>In-frame_ENST00000592199_ENST00000585892_TCGA-34-8456-01A_NFIX_chr19_13106678_+_DNM2_chr19_10897240_length(transcript)=1788nt_BP=27nt
ATGTACTCCCCGTACTGCCTCACCCAGCAACTGACCAACCACATCCGGGAGTCGCTGCCGGCCCTACGTAGCAAACTACAGAGCCAGCTG
CTGTCCCTGGAGAAGGAGGTGGAGGAGTACAAGAACTTTCGGCCCGACGACCCCACCCGCAAAACCAAAGCCCTGCTGCAGATGGTCCAG
CAGTTTGGGGTGGATTTTGAGAAGAGGATCGAGGGCTCAGGAGATCAGGTGGACACTCTGGAGCTCTCCGGGGGCGCCCGAATCAATCGC
ATCTTCCACGAGCGGTTCCCATTTGAGCTGGTGAAGATGGAGTTTGACGAGAAGGACTTACGACGGGAGATCAGCTATGCCATTAAGAAC
ATCCATGGAGTCAGGACCGGGCTTTTCACCCCGGACTTGGCATTCGAGGCCATTGTGAAAAAGCAGGTCGTCAAGCTGAAAGAGCCCTGT
CTGAAATGTGTCGACCTGGTTATCCAGGAGCTAATCAATACAGTTAGGCAGTGTACCAGTAAGCTCAGTTCCTACCCCCGGTTGCGAGAG
GAGACAGAGCGAATCGTCACCACTTACATCCGGGAACGGGAGGGGAGAACGAAGGACCAGATTCTTCTGCTGATCGACATTGAGCAGTCC
TACATCAACACGAACCATGAGGACTTCATCGGGTTTGCCAATGCCCAGCAGAGGAGCACGCAGCTGAACAAGAAGAGAGCCATCCCCAAT
CAGGGGGAGATCCTGGTGATCCGCAGGGGCTGGCTGACCATCAACAACATCAGCCTGATGAAAGGCGGCTCCAAGGAGTACTGGTTTGTG
CTGACTGCCGAGTCACTGTCCTGGTACAAGGATGAGGAGGAGAAAGAGAAGAAGTACATGCTGCCTCTGGACAACCTCAAGATCCGTGAT
GTGGAGAAGGGCTTCATGTCCAACAAGCACGTCTTCGCCATCTTCAACACGGAGCAGAGAAACGTCTACAAGGACCTGCGGCAGATCGAG
CTGGCCTGTGACTCCCAGGAAGACGTGGACAGCTGGAAGGCCTCGTTCCTCCGAGCTGGCGTCTACCCCGAGAAGGACCAGGCAGAAAAC
GAGGATGGGGCCCAGGAGAACACCTTCTCCATGGACCCCCAACTGGAGCGGCAGGTGGAGACCATTCGCAACCTGGTGGACTCATACGTG
GCCATCATCAACAAGTCCATCCGCGACCTCATGCCAAAGACCATCATGCACCTCATGATCAACAATACGAAGGCCTTCATCCACCACGAG
CTGCTGGCCTACCTATACTCCTCGGCAGACCAGAGCAGCCTCATGGAGGAGTCGGCTGACCAGGCACAGCGGCGGGACGACATGCTGCGC
ATGTACCATGCCCTCAAGGAGGCGCTCAACATCATCGGTGACATCAGCACCAGCACTGTGTCCACGCCTGTACCCCCGCCTGTCGATGAC
ACCTGGCTCCAGAGCGCCAGCAGCCACAGCCCCACTCCACAGCGCCGACCGGTGTCCAGCATACACCCCCCTGGCCGGCCCCCAGCAGTG
AGGGGCCCCACTCCAGGGCCCCCCCTGATTCCTGTTCCCGTGGGGGCAGCAGCCTCCTTCTCGGCGCCCCCAATCCCATCCCGGCCTGGA
CCCCAGAGCGTGTTTGCCAACAGTGACCTCTTCCCAGCCCCGCCTCAGATCCCATCTCGGCCAGTTCGGATCCCCCCAGGGATTCCCCCA

>In-frame_ENST00000592199_ENST00000585892_TCGA-34-8456-01A_NFIX_chr19_13106678_+_DNM2_chr19_10897240_length(amino acids)=595AA_start in transcript=0_stop in transcript=1787
MYSPYCLTQQLTNHIRESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGARINR
IFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAFEAIVKKQVVKLKEPCLKCVDLVIQELINTVRQCTSKLSSYPRLRE
ETERIVTTYIREREGRTKDQILLLIDIEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQGEILVIRRGWLTINNISLMKGGSKEYWFV
LTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIELACDSQEDVDSWKASFLRAGVYPEKDQAEN
EDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLR
MYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPG

--------------------------------------------------------------
>In-frame_ENST00000592199_ENST00000314646_TCGA-34-8456-01A_NFIX_chr19_13106678_+_DNM2_chr19_10897240_length(transcript)=2647nt_BP=27nt
ATGTACTCCCCGTACTGCCTCACCCAGCAACTGACCAACCACATCCGGGAGTCGCTGCCGGCCCTACGTAGCAAACTACAGAGCCAGCTG
CTGTCCCTGGAGAAGGAGGTGGAGGAGTACAAGAACTTTCGGCCCGACGACCCCACCCGCAAAACCAAAGCCCTGCTGCAGATGGTCCAG
CAGTTTGGGGTGGATTTTGAGAAGAGGATCGAGGGCTCAGGAGATCAGGTGGACACTCTGGAGCTCTCCGGGGGCGCCCGAATCAATCGC
ATCTTCCACGAGCGGTTCCCATTTGAGCTGGTGAAGATGGAGTTTGACGAGAAGGACTTACGACGGGAGATCAGCTATGCCATTAAGAAC
ATCCATGGAGTCAGGACGGGGCTCTTCACCCCCGACATGGCCTTTGAAGCCATTGTGAAAAAACAGATTGTAAAACTCAAAGAGCCGAGT
TTGAAGTGTGTTGATCTCGTGGTCTCAGAGCTGGCCACGGTCATAAAAAAGTGTGCCGAGAAGCTCAGTTCCTACCCCCGGTTGCGAGAG
GAGACAGAGCGAATCGTCACCACTTACATCCGGGAACGGGAGGGGAGAACGAAGGACCAGATTCTTCTGCTGATCGACATTGAGCAGTCC
TACATCAACACGAACCATGAGGACTTCATCGGGTTTGCCAATGCCCAGCAGAGGAGCACGCAGCTGAACAAGAAGAGAGCCATCCCCAAT
CAGCCTGAAACCCTGGTGATCCGCAGGGGCTGGCTGACCATCAACAACATCAGCCTGATGAAAGGCGGCTCCAAGGAGTACTGGTTTGTG
CTGACTGCCGAGTCACTGTCCTGGTACAAGGATGAGGAGGAGAAAGAGAAGAAGTACATGCTGCCTCTGGACAACCTCAAGATCCGTGAT
GTGGAGAAGGGCTTCATGTCCAACAAGCACGTCTTCGCCATCTTCAACACGGAGCAGAGAAACGTCTACAAGGACCTGCGGCAGATCGAG
CTGGCCTGTGACTCCCAGGAAGACGTGGACAGCTGGAAGGCCTCGTTCCTCCGAGCTGGCGTCTACCCCGAGAAGGACCAGGCAGAAAAC
GAGGATGGGGCCCAGGAGAACACCTTCTCCATGGACCCCCAACTGGAGCGGCAGGTGGAGACCATTCGCAACCTGGTGGACTCATACGTG
GCCATCATCAACAAGTCCATCCGCGACCTCATGCCAAAGACCATCATGCACCTCATGATCAACAATACGAAGGCCTTCATCCACCACGAG
CTGCTGGCCTACCTATACTCCTCGGCAGACCAGAGCAGCCTCATGGAGGAGTCGGCTGACCAGGCACAGCGGCGGGACGACATGCTGCGC
ATGTACCATGCCCTCAAGGAGGCGCTCAACATCATCGGTGACATCAGCACCAGCACTGTGTCCACGCCTGTACCCCCGCCTGTCGATGAC
ACCTGGCTCCAGAGCGCCAGCAGCCACAGCCCCACTCCACAGCGCCGACCGGTGTCCAGCATACACCCCCCTGGCCGGCCCCCAGCAGTG
AGGGGCCCCACTCCAGGGCCCCCCCTGATTCCTGTTCCCGTGGGGGCAGCAGCCTCCTTCTCGGCGCCCCCAATCCCATCCCGGCCTGGA
CCCCAGAGCGTGTTTGCCAACAGTGACCTCTTCCCAGCCCCGCCTCAGATCCCATCTCGGCCAGTTCGGATCCCCCCAGGGATTCCCCCA
GGAGTGCCCAGCAGAAGACCCCCTGCTGCGCCCAGCCGGCCCACCATTATCCGCCCAGCCGAGCCATCCCTGCTCGACTAGGCCTCGAGG
GGGGCGTGCTCTCGGGGGGGCCTCACGCACCCGCGGCGCAGGAGCTTCAGTGGTCTGGGGCCCTCCGCCGCCCCTATGCTGGGACCAGGC
TCCCAGTGGGCAGCCCTGGCCTCTTCCTTAACGCTGGCCCCGGTCCAGGGCCGGCCCCTGTGCCTGGCTGGACACCGCACTGCGCAAAGG
GGCCCTGGAGCTCCAGGCAGGGGGCGCTGGGGTGTTGCACTTTGGGGGATGGAGTCTCAGGGTGGCAGAGGGGGGACCAGAACCCTTGAC
ACCATCCTGAATGAGGGGTCCAGCCTGGGGGGGACTCTACCAAGGTCTTCTTGGGCTGGGAAAGCCCATGTAGGGCAGGCCTTCTATAAG
TGCGGGCACCAAGGGCGCCTACATCCCCAGGCCTTGCTGGGGTGCAGGGGTATATCAACTTCCCATTAGCAGGAGCTCCCCAGCGGCAAG
CCTGGCCCAGTGGGCTCGGTAGTGCCCAGCTGGCAGGCCTGAGGTGTACATAGTCCTTCCCGGCCATATTAACCACACAGCCTGAGCCTG
GCCCAGCCTCGGCTGCCAGAGGTGCCTTTGCTAGGCCCGGAGCCGTTGGCCCGGGCCGGCCTTGCCCTATTCCTCTCCTCCTCCTCCTCC
TGGGTCCCCCAGGGTGGCTGGGCTTGGGCTATGTGGGTGGTGGTGGCGGGGGGTCTTGGGGGCCTCTCAGCTCCCGCCCATGCCTCCCTG
ATGGGTGGGCCCAGGGCGGCCTCTCTCTGAGGAGACCTCACCCACTCCTCGCTCAGTTTGACCACTGTAAGTGCCTGCACTCTGTATTCT

>In-frame_ENST00000592199_ENST00000314646_TCGA-34-8456-01A_NFIX_chr19_13106678_+_DNM2_chr19_10897240_length(amino acids)=596AA_start in transcript=0_stop in transcript=1790
MYSPYCLTQQLTNHIRESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGARINR
IFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDMAFEAIVKKQIVKLKEPSLKCVDLVVSELATVIKKCAEKLSSYPRLRE
ETERIVTTYIREREGRTKDQILLLIDIEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQPETLVIRRGWLTINNISLMKGGSKEYWFV
LTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIELACDSQEDVDSWKASFLRAGVYPEKDQAEN
EDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLR
MYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPG

--------------------------------------------------------------
>In-frame_ENST00000592199_ENST00000359692_TCGA-34-8456-01A_NFIX_chr19_13106678_+_DNM2_chr19_10897240_length(transcript)=2616nt_BP=27nt
ATGTACTCCCCGTACTGCCTCACCCAGCAACTGACCAACCACATCCGGGAGTCGCTGCCGGCCCTACGTAGCAAACTACAGAGCCAGCTG
CTGTCCCTGGAGAAGGAGGTGGAGGAGTACAAGAACTTTCGGCCCGACGACCCCACCCGCAAAACCAAAGCCCTGCTGCAGATGGTCCAG
CAGTTTGGGGTGGATTTTGAGAAGAGGATCGAGGGCTCAGGAGATCAGGTGGACACTCTGGAGCTCTCCGGGGGCGCCCGAATCAATCGC
ATCTTCCACGAGCGGTTCCCATTTGAGCTGGTGAAGATGGAGTTTGACGAGAAGGACTTACGACGGGAGATCAGCTATGCCATTAAGAAC
ATCCATGGAGTCAGGACCGGGCTTTTCACCCCGGACTTGGCATTCGAGGCCATTGTGAAAAAGCAGGTCGTCAAGCTGAAAGAGCCCTGT
CTGAAATGTGTCGACCTGGTTATCCAGGAGCTAATCAATACAGTTAGGCAGTGTACCAGTAAGCTCAGTTCCTACCCCCGGTTGCGAGAG
GAGACAGAGCGAATCGTCACCACTTACATCCGGGAACGGGAGGGGAGAACGAAGGACCAGATTCTTCTGCTGATCGACATTGAGCAGTCC
TACATCAACACGAACCATGAGGACTTCATCGGGTTTGCCAATGCCCAGCAGAGGAGCACGCAGCTGAACAAGAAGAGAGCCATCCCCAAT
CAGGTGATCCGCAGGGGCTGGCTGACCATCAACAACATCAGCCTGATGAAAGGCGGCTCCAAGGAGTACTGGTTTGTGCTGACTGCCGAG
TCACTGTCCTGGTACAAGGATGAGGAGGAGAAAGAGAAGAAGTACATGCTGCCTCTGGACAACCTCAAGATCCGTGATGTGGAGAAGGGC
TTCATGTCCAACAAGCACGTCTTCGCCATCTTCAACACGGAGCAGAGAAACGTCTACAAGGACCTGCGGCAGATCGAGCTGGCCTGTGAC
TCCCAGGAAGACGTGGACAGCTGGAAGGCCTCGTTCCTCCGAGCTGGCGTCTACCCCGAGAAGGACCAGGCAGAAAACGAGGATGGGGCC
CAGGAGAACACCTTCTCCATGGACCCCCAACTGGAGCGGCAGGTGGAGACCATTCGCAACCTGGTGGACTCATACGTGGCCATCATCAAC
AAGTCCATCCGCGACCTCATGCCAAAGACCATCATGCACCTCATGATCAACAATACGAAGGCCTTCATCCACCACGAGCTGCTGGCCTAC
CTATACTCCTCGGCAGACCAGAGCAGCCTCATGGAGGAGTCGGCTGACCAGGCACAGCGGCGGGACGACATGCTGCGCATGTACCATGCC
CTCAAGGAGGCGCTCAACATCATCGGTGACATCAGCACCAGCACTGTGTCCACGCCTGTACCCCCGCCTGTCGATGACACCTGGCTCCAG
AGCGCCAGCAGCCACAGCCCCACTCCACAGCGCCGACCGGTGTCCAGCATACACCCCCCTGGCCGGCCCCCAGCAGTGAGGGGCCCCACT
CCAGGGCCCCCCCTGATTCCTGTTCCCGTGGGGGCAGCAGCCTCCTTCTCGGCGCCCCCAATCCCATCCCGGCCTGGACCCCAGAGCGTG
TTTGCCAACAGTGACCTCTTCCCAGCCCCGCCTCAGATCCCATCTCGGCCAGTTCGGATCCCCCCAGGGATTCCCCCAGGAGTGCCCAGC
AGAAGACCCCCTGCTGCGCCCAGCCGGCCCACCATTATCCGCCCAGCCGAGCCATCCCTGCTCGACTAGGCCTCGAGGGGGGCGTGCTCT
CGGGGGGGCCTCACGCACCCGCGGCGCAGGAGCTTCAGTGGTCTGGGGCCCTCCGCCGCCCCTATGCTGGGACCAGGCTCCCAGTGGGCA
GCCCTGGCCTCTTCCTTAACGCTGGCCCCGGTCCAGGGCCGGCCCCTGTGCCTGGCTGGACACCGCACTGCGCAAAGGGGCCCTGGAGCT
CCAGGCAGGGGGCGCTGGGGTGTTGCACTTTGGGGGATGGAGTCTCAGGGTGGCAGAGGGGGGACCAGAACCCTTGACACCATCCTGAAT
GAGGGGTCCAGCCTGGGGGGGACTCTACCAAGGTCTTCTTGGGCTGGGAAAGCCCATGTAGGGCAGGCCTTCTATAAGTGCGGGCACCAA
GGGCGCCTACATCCCCAGGCCTTGCTGGGGTGCAGGGGTATATCAACTTCCCATTAGCAGGAGCTCCCCAGCGGCAAGCCTGGCCCAGTG
GGCTCGGTAGTGCCCAGCTGGCAGGCCTGAGGTGTACATAGTCCTTCCCGGCCATATTAACCACACAGCCTGAGCCTGGCCCAGCCTCGG
CTGCCAGAGGTGCCTTTGCTAGGCCCGGAGCCGTTGGCCCGGGCCGGCCTTGCCCTATTCCTCTCCTCCTCCTCCTCCTGGGTCCCCCAG
GGTGGCTGGGCTTGGGCTATGTGGGTGGTGGTGGCGGGGGGTCTTGGGGGCCTCTCAGCTCCCGCCCATGCCTCCCTGATGGGTGGGCCC
AGGGCGGCCTCTCTCTGAGGAGACCTCACCCACTCCTCGCTCAGTTTGACCACTGTAAGTGCCTGCACTCTGTATTCTATTAATAAACTA

>In-frame_ENST00000592199_ENST00000359692_TCGA-34-8456-01A_NFIX_chr19_13106678_+_DNM2_chr19_10897240_length(amino acids)=592AA_start in transcript=0_stop in transcript=1778
MYSPYCLTQQLTNHIRESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGARINR
IFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAFEAIVKKQVVKLKEPCLKCVDLVIQELINTVRQCTSKLSSYPRLRE
ETERIVTTYIREREGRTKDQILLLIDIEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQVIRRGWLTINNISLMKGGSKEYWFVLTAE
SLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIELACDSQEDVDSWKASFLRAGVYPEKDQAENEDGA
QENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLRMYHA
LKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSV

--------------------------------------------------------------
>In-frame_ENST00000592199_ENST00000389253_TCGA-34-8456-01A_NFIX_chr19_13106678_+_DNM2_chr19_10897240_length(transcript)=2647nt_BP=27nt
ATGTACTCCCCGTACTGCCTCACCCAGCAACTGACCAACCACATCCGGGAGTCGCTGCCGGCCCTACGTAGCAAACTACAGAGCCAGCTG
CTGTCCCTGGAGAAGGAGGTGGAGGAGTACAAGAACTTTCGGCCCGACGACCCCACCCGCAAAACCAAAGCCCTGCTGCAGATGGTCCAG
CAGTTTGGGGTGGATTTTGAGAAGAGGATCGAGGGCTCAGGAGATCAGGTGGACACTCTGGAGCTCTCCGGGGGCGCCCGAATCAATCGC
ATCTTCCACGAGCGGTTCCCATTTGAGCTGGTGAAGATGGAGTTTGACGAGAAGGACTTACGACGGGAGATCAGCTATGCCATTAAGAAC
ATCCATGGAGTCAGGACGGGGCTCTTCACCCCCGACATGGCCTTTGAAGCCATTGTGAAAAAACAGATTGTAAAACTCAAAGAGCCGAGT
TTGAAGTGTGTTGATCTCGTGGTCTCAGAGCTGGCCACGGTCATAAAAAAGTGTGCCGAGAAGCTCAGTTCCTACCCCCGGTTGCGAGAG
GAGACAGAGCGAATCGTCACCACTTACATCCGGGAACGGGAGGGGAGAACGAAGGACCAGATTCTTCTGCTGATCGACATTGAGCAGTCC
TACATCAACACGAACCATGAGGACTTCATCGGGTTTGCCAATGCCCAGCAGAGGAGCACGCAGCTGAACAAGAAGAGAGCCATCCCCAAT
CAGGGGGAGATCCTGGTGATCCGCAGGGGCTGGCTGACCATCAACAACATCAGCCTGATGAAAGGCGGCTCCAAGGAGTACTGGTTTGTG
CTGACTGCCGAGTCACTGTCCTGGTACAAGGATGAGGAGGAGAAAGAGAAGAAGTACATGCTGCCTCTGGACAACCTCAAGATCCGTGAT
GTGGAGAAGGGCTTCATGTCCAACAAGCACGTCTTCGCCATCTTCAACACGGAGCAGAGAAACGTCTACAAGGACCTGCGGCAGATCGAG
CTGGCCTGTGACTCCCAGGAAGACGTGGACAGCTGGAAGGCCTCGTTCCTCCGAGCTGGCGTCTACCCCGAGAAGGACCAGGCAGAAAAC
GAGGATGGGGCCCAGGAGAACACCTTCTCCATGGACCCCCAACTGGAGCGGCAGGTGGAGACCATTCGCAACCTGGTGGACTCATACGTG
GCCATCATCAACAAGTCCATCCGCGACCTCATGCCAAAGACCATCATGCACCTCATGATCAACAATACGAAGGCCTTCATCCACCACGAG
CTGCTGGCCTACCTATACTCCTCGGCAGACCAGAGCAGCCTCATGGAGGAGTCGGCTGACCAGGCACAGCGGCGGGACGACATGCTGCGC
ATGTACCATGCCCTCAAGGAGGCGCTCAACATCATCGGTGACATCAGCACCAGCACTGTGTCCACGCCTGTACCCCCGCCTGTCGATGAC
ACCTGGCTCCAGAGCGCCAGCAGCCACAGCCCCACTCCACAGCGCCGACCGGTGTCCAGCATACACCCCCCTGGCCGGCCCCCAGCAGTG
AGGGGCCCCACTCCAGGGCCCCCCCTGATTCCTGTTCCCGTGGGGGCAGCAGCCTCCTTCTCGGCGCCCCCAATCCCATCCCGGCCTGGA
CCCCAGAGCGTGTTTGCCAACAGTGACCTCTTCCCAGCCCCGCCTCAGATCCCATCTCGGCCAGTTCGGATCCCCCCAGGGATTCCCCCA
GGAGTGCCCAGCAGAAGACCCCCTGCTGCGCCCAGCCGGCCCACCATTATCCGCCCAGCCGAGCCATCCCTGCTCGACTAGGCCTCGAGG
GGGGCGTGCTCTCGGGGGGGCCTCACGCACCCGCGGCGCAGGAGCTTCAGTGGTCTGGGGCCCTCCGCCGCCCCTATGCTGGGACCAGGC
TCCCAGTGGGCAGCCCTGGCCTCTTCCTTAACGCTGGCCCCGGTCCAGGGCCGGCCCCTGTGCCTGGCTGGACACCGCACTGCGCAAAGG
GGCCCTGGAGCTCCAGGCAGGGGGCGCTGGGGTGTTGCACTTTGGGGGATGGAGTCTCAGGGTGGCAGAGGGGGGACCAGAACCCTTGAC
ACCATCCTGAATGAGGGGTCCAGCCTGGGGGGGACTCTACCAAGGTCTTCTTGGGCTGGGAAAGCCCATGTAGGGCAGGCCTTCTATAAG
TGCGGGCACCAAGGGCGCCTACATCCCCAGGCCTTGCTGGGGTGCAGGGGTATATCAACTTCCCATTAGCAGGAGCTCCCCAGCGGCAAG
CCTGGCCCAGTGGGCTCGGTAGTGCCCAGCTGGCAGGCCTGAGGTGTACATAGTCCTTCCCGGCCATATTAACCACACAGCCTGAGCCTG
GCCCAGCCTCGGCTGCCAGAGGTGCCTTTGCTAGGCCCGGAGCCGTTGGCCCGGGCCGGCCTTGCCCTATTCCTCTCCTCCTCCTCCTCC
TGGGTCCCCCAGGGTGGCTGGGCTTGGGCTATGTGGGTGGTGGTGGCGGGGGGTCTTGGGGGCCTCTCAGCTCCCGCCCATGCCTCCCTG
ATGGGTGGGCCCAGGGCGGCCTCTCTCTGAGGAGACCTCACCCACTCCTCGCTCAGTTTGACCACTGTAAGTGCCTGCACTCTGTATTCT

>In-frame_ENST00000592199_ENST00000389253_TCGA-34-8456-01A_NFIX_chr19_13106678_+_DNM2_chr19_10897240_length(amino acids)=596AA_start in transcript=0_stop in transcript=1790
MYSPYCLTQQLTNHIRESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGARINR
IFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDMAFEAIVKKQIVKLKEPSLKCVDLVVSELATVIKKCAEKLSSYPRLRE
ETERIVTTYIREREGRTKDQILLLIDIEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQGEILVIRRGWLTINNISLMKGGSKEYWFV
LTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIELACDSQEDVDSWKASFLRAGVYPEKDQAEN
EDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLR
MYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPG

--------------------------------------------------------------
>In-frame_ENST00000592199_ENST00000355667_TCGA-34-8456-01A_NFIX_chr19_13106678_+_DNM2_chr19_10897240_length(transcript)=2639nt_BP=27nt
ATGTACTCCCCGTACTGCCTCACCCAGCAACTGACCAACCACATCCGGGAGTCGCTGCCGGCCCTACGTAGCAAACTACAGAGCCAGCTG
CTGTCCCTGGAGAAGGAGGTGGAGGAGTACAAGAACTTTCGGCCCGACGACCCCACCCGCAAAACCAAAGCCCTGCTGCAGATGGTCCAG
CAGTTTGGGGTGGATTTTGAGAAGAGGATCGAGGGCTCAGGAGATCAGGTGGACACTCTGGAGCTCTCCGGGGGCGCCCGAATCAATCGC
ATCTTCCACGAGCGGTTCCCATTTGAGCTGGTGAAGATGGAGTTTGACGAGAAGGACTTACGACGGGAGATCAGCTATGCCATTAAGAAC
ATCCATGGAGTCAGGACCGGGCTTTTCACCCCGGACTTGGCATTCGAGGCCATTGTGAAAAAGCAGGTCGTCAAGCTGAAAGAGCCCTGT
CTGAAATGTGTCGACCTGGTTATCCAGGAGCTAATCAATACAGTTAGGCAGTGTACCAGTAAGCTCAGTTCCTACCCCCGGTTGCGAGAG
GAGACAGAGCGAATCGTCACCACTTACATCCGGGAACGGGAGGGGAGAACGAAGGACCAGATTCTTCTGCTGATCGACATTGAGCAGTCC
TACATCAACACGAACCATGAGGACTTCATCGGGTTTGCCAATGCCCAGCAGAGGAGCACGCAGCTGAACAAGAAGAGAGCCATCCCCAAT
CAGGGGGAGATCCTGGTGATCCGCAGGGGCTGGCTGACCATCAACAACATCAGCCTGATGAAAGGCGGCTCCAAGGAGTACTGGTTTGTG
CTGACTGCCGAGTCACTGTCCTGGTACAAGGATGAGGAGGAGAAAGAGAAGAAGTACATGCTGCCTCTGGACAACCTCAAGATCCGTGAT
GTGGAGAAGGGCTTCATGTCCAACAAGCACGTCTTCGCCATCTTCAACACGGAGCAGAGAAACGTCTACAAGGACCTGCGGCAGATCGAG
CTGGCCTGTGACTCCCAGGAAGACGTGGACAGCTGGAAGGCCTCGTTCCTCCGAGCTGGCGTCTACCCCGAGAAGGACCAGGCAGAAAAC
GAGGATGGGGCCCAGGAGAACACCTTCTCCATGGACCCCCAACTGGAGCGGCAGGTGGAGACCATTCGCAACCTGGTGGACTCATACGTG
GCCATCATCAACAAGTCCATCCGCGACCTCATGCCAAAGACCATCATGCACCTCATGATCAACAATACGAAGGCCTTCATCCACCACGAG
CTGCTGGCCTACCTATACTCCTCGGCAGACCAGAGCAGCCTCATGGAGGAGTCGGCTGACCAGGCACAGCGGCGGGACGACATGCTGCGC
ATGTACCATGCCCTCAAGGAGGCGCTCAACATCATCGGTGACATCAGCACCAGCACTGTGTCCACGCCTGTACCCCCGCCTGTCGATGAC
ACCTGGCTCCAGAGCGCCAGCAGCCACAGCCCCACTCCACAGCGCCGACCGGTGTCCAGCATACACCCCCCTGGCCGGCCCCCAGCAGTG
AGGGGCCCCACTCCAGGGCCCCCCCTGATTCCTGTTCCCGTGGGGGCAGCAGCCTCCTTCTCGGCGCCCCCAATCCCATCCCGGCCTGGA
CCCCAGAGCGTGTTTGCCAACAGTGACCTCTTCCCAGCCCCGCCTCAGATCCCATCTCGGCCAGTTCGGATCCCCCCAGGGATTCCCCCA
GGAGTGCCCAGCAGAAGACCCCCTGCTGCGCCCAGCCGGCCCACCATTATCCGCCCAGCCGAGCCATCCCTGCTCGACTAGGCCTCGAGG
GGGGCGTGCTCTCGGGGGGGCCTCACGCACCCGCGGCGCAGGAGCTTCAGTGGTCTGGGGCCCTCCGCCGCCCCTATGCTGGGACCAGGC
TCCCAGTGGGCAGCCCTGGCCTCTTCCTTAACGCTGGCCCCGGTCCAGGGCCGGCCCCTGTGCCTGGCTGGACACCGCACTGCGCAAAGG
GGCCCTGGAGCTCCAGGCAGGGGGCGCTGGGGTGTTGCACTTTGGGGGATGGAGTCTCAGGGTGGCAGAGGGGGGACCAGAACCCTTGAC
ACCATCCTGAATGAGGGGTCCAGCCTGGGGGGGACTCTACCAAGGTCTTCTTGGGCTGGGAAAGCCCATGTAGGGCAGGCCTTCTATAAG
TGCGGGCACCAAGGGCGCCTACATCCCCAGGCCTTGCTGGGGTGCAGGGGTATATCAACTTCCCATTAGCAGGAGCTCCCCAGCGGCAAG
CCTGGCCCAGTGGGCTCGGTAGTGCCCAGCTGGCAGGCCTGAGGTGTACATAGTCCTTCCCGGCCATATTAACCACACAGCCTGAGCCTG
GCCCAGCCTCGGCTGCCAGAGGTGCCTTTGCTAGGCCCGGAGCCGTTGGCCCGGGCCGGCCTTGCCCTATTCCTCTCCTCCTCCTCCTCC
TGGGTCCCCCAGGGTGGCTGGGCTTGGGCTATGTGGGTGGTGGTGGCGGGGGGTCTTGGGGGCCTCTCAGCTCCCGCCCATGCCTCCCTG
ATGGGTGGGCCCAGGGCGGCCTCTCTCTGAGGAGACCTCACCCACTCCTCGCTCAGTTTGACCACTGTAAGTGCCTGCACTCTGTATTCT

>In-frame_ENST00000592199_ENST00000355667_TCGA-34-8456-01A_NFIX_chr19_13106678_+_DNM2_chr19_10897240_length(amino acids)=596AA_start in transcript=0_stop in transcript=1790
MYSPYCLTQQLTNHIRESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGARINR
IFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAFEAIVKKQVVKLKEPCLKCVDLVIQELINTVRQCTSKLSSYPRLRE
ETERIVTTYIREREGRTKDQILLLIDIEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQGEILVIRRGWLTINNISLMKGGSKEYWFV
LTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIELACDSQEDVDSWKASFLRAGVYPEKDQAEN
EDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLR
MYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPG

--------------------------------------------------------------
>In-frame_ENST00000592199_ENST00000408974_TCGA-34-8456-01A_NFIX_chr19_13106678_+_DNM2_chr19_10897240_length(transcript)=2156nt_BP=27nt
ATGTACTCCCCGTACTGCCTCACCCAGCAACTGACCAACCACATCCGGGAGTCGCTGCCGGCCCTACGTAGCAAACTACAGAGCCAGCTG
CTGTCCCTGGAGAAGGAGGTGGAGGAGTACAAGAACTTTCGGCCCGACGACCCCACCCGCAAAACCAAAGCCCTGCTGCAGATGGTCCAG
CAGTTTGGGGTGGATTTTGAGAAGAGGATCGAGGGCTCAGGAGATCAGGTGGACACTCTGGAGCTCTCCGGGGGCGCCCGAATCAATCGC
ATCTTCCACGAGCGGTTCCCATTTGAGCTGGTGAAGATGGAGTTTGACGAGAAGGACTTACGACGGGAGATCAGCTATGCCATTAAGAAC
ATCCATGGAGTCAGGACGGGGCTCTTCACCCCCGACATGGCCTTTGAAGCCATTGTGAAAAAACAGATTGTAAAACTCAAAGAGCCGAGT
TTGAAGTGTGTTGATCTCGTGGTCTCAGAGCTGGCCACGGTCATAAAAAAGTGTGCCGAGAAGCTCAGTTCCTACCCCCGGTTGCGAGAG
GAGACAGAGCGAATCGTCACCACTTACATCCGGGAACGGGAGGGGAGAACGAAGGACCAGATTCTTCTGCTGATCGACATTGAGCAGTCC
TACATCAACACGAACCATGAGGACTTCATCGGGTTTGCCAATGCCCAGCAGAGGAGCACGCAGCTGAACAAGAAGAGAGCCATCCCCAAT
CAGGTGATCCGCAGGGGCTGGCTGACCATCAACAACATCAGCCTGATGAAAGGCGGCTCCAAGGAGTACTGGTTTGTGCTGACTGCCGAG
TCACTGTCCTGGTACAAGGATGAGGAGGAGAAAGAGAAGAAGTACATGCTGCCTCTGGACAACCTCAAGATCCGTGATGTGGAGAAGGGC
TTCATGTCCAACAAGCACGTCTTCGCCATCTTCAACACGGAGCAGAGAAACGTCTACAAGGACCTGCGGCAGATCGAGCTGGCCTGTGAC
TCCCAGGAAGACGTGGACAGCTGGAAGGCCTCGTTCCTCCGAGCTGGCGTCTACCCCGAGAAGGACCAGGCAGAAAACGAGGATGGGGCC
CAGGAGAACACCTTCTCCATGGACCCCCAACTGGAGCGGCAGGTGGAGACCATTCGCAACCTGGTGGACTCATACGTGGCCATCATCAAC
AAGTCCATCCGCGACCTCATGCCAAAGACCATCATGCACCTCATGATCAACAATACGAAGGCCTTCATCCACCACGAGCTGCTGGCCTAC
CTATACTCCTCGGCAGACCAGAGCAGCCTCATGGAGGAGTCGGCTGACCAGGCACAGCGGCGGGACGACATGCTGCGCATGTACCATGCC
CTCAAGGAGGCGCTCAACATCATCGGTGACATCAGCACCAGCACTGTGTCCACGCCTGTACCCCCGCCTGTCGATGACACCTGGCTCCAG
AGCGCCAGCAGCCACAGCCCCACTCCACAGCGCCGACCGGTGTCCAGCATACACCCCCCTGGCCGGCCCCCAGCAGTGAGGGGCCCCACT
CCAGGGCCCCCCCTGATTCCTGTTCCCGTGGGGGCAGCAGCCTCCTTCTCGGCGCCCCCAATCCCATCCCGGCCTGGACCCCAGAGCGTG
TTTGCCAACAGTGACCTCTTCCCAGCCCCGCCTCAGATCCCATCTCGGCCAGTTCGGATCCCCCCAGGGATTCCCCCAGGAGTGCCCAGC
AGAAGACCCCCTGCTGCGCCCAGCCGGCCCACCATTATCCGCCCAGCCGAGCCATCCCTGCTCGACTAGGCCTCGAGGGGGGCGTGCTCT
CGGGGGGGCCTCACGCACCCGCGGCGCAGGAGCTTCAGTGGTCTGGGGCCCTCCGCCGCCCCTATGCTGGGACCAGGCTCCCAGTGGGCA
GCCCTGGCCTCTTCCTTAACGCTGGCCCCGGTCCAGGGCCGGCCCCTGTGCCTGGCTGGACACCGCACTGCGCAAAGGGGCCCTGGAGCT
CCAGGCAGGGGGCGCTGGGGTGTTGCACTTTGGGGGATGGAGTCTCAGGGTGGCAGAGGGGGGACCAGAACCCTTGACACCATCCTGAAT

>In-frame_ENST00000592199_ENST00000408974_TCGA-34-8456-01A_NFIX_chr19_13106678_+_DNM2_chr19_10897240_length(amino acids)=592AA_start in transcript=0_stop in transcript=1778
MYSPYCLTQQLTNHIRESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGARINR
IFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDMAFEAIVKKQIVKLKEPSLKCVDLVVSELATVIKKCAEKLSSYPRLRE
ETERIVTTYIREREGRTKDQILLLIDIEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQVIRRGWLTINNISLMKGGSKEYWFVLTAE
SLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIELACDSQEDVDSWKASFLRAGVYPEKDQAENEDGA
QENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLRMYHA
LKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSV

--------------------------------------------------------------

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Fusion Gene PPI Analysis for NFIX-DNM2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for NFIX-DNM2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for NFIX-DNM2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneNFIXC3553660Malan overgrowth syndrome5GENOMICS_ENGLAND;ORPHANET;UNIPROT
HgeneNFIXC0265211Marshall-Smith syndrome2CTD_human;GENOMICS_ENGLAND;ORPHANET
HgeneNFIXC0005586Bipolar Disorder1PSYGENET
TgeneDNM2C4551952Myopathy, Centronuclear, 113CTD_human;GENOMICS_ENGLAND;UNIPROT
TgeneDNM2C1847902CHARCOT-MARIE-TOOTH DISEASE, DOMINANT INTERMEDIATE B (disorder)8CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
TgeneDNM2C1834558Myopathy, Centronuclear, Autosomal Dominant7CLINGEN;CTD_human;ORPHANET
TgeneDNM2C0175709Centronuclear myopathy2CTD_human;GENOMICS_ENGLAND
TgeneDNM2C3809272LETHAL CONGENITAL CONTRACTURE SYNDROME 52CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
TgeneDNM2C0410203X-linked centronuclear myopathy1CTD_human
TgeneDNM2C0410207Tubular Aggregate Myopathy1CTD_human
TgeneDNM2C0546264Congenital Fiber Type Disproportion1CTD_human
TgeneDNM2C0752282Congenital Structural Myopathy1CTD_human
TgeneDNM2C3645536Autosomal Recessive Centronuclear Myopathy1CTD_human
TgeneDNM2C3661489Autosomal Dominant Myotubular Myopathy1CTD_human