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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:NPEPPS-ARL17B (FusionGDB2 ID:59514)

Fusion Gene Summary for NPEPPS-ARL17B

check button Fusion gene summary
Fusion gene informationFusion gene name: NPEPPS-ARL17B
Fusion gene ID: 59514
HgeneTgene
Gene symbol

NPEPPS

ARL17B

Gene ID

9520

100506084

Gene nameaminopeptidase puromycin sensitiveADP ribosylation factor like GTPase 17B
SynonymsAAP-S|MP100|PSAARL17|ARL17A
Cytomap

17q21.32

17q21.31

Type of geneprotein-codingprotein-coding
Descriptionpuromycin-sensitive aminopeptidasecytosol alanyl aminopeptidasemetalloproteinase MP100ADP-ribosylation factor-like protein 17ADP-ribosylation factor 7ADP-ribosylation factor-like 17B
Modification date2020031320200313
UniProtAcc

P55786

.
Ensembl transtripts involved in fusion geneENST00000525037, ENST00000530173, 
ENST00000322157, ENST00000544660, 
ENST00000570618, ENST00000434041, 
ENST00000575698, ENST00000575960, 
ENST00000571246, ENST00000450673, 
Fusion gene scores* DoF score18 X 9 X 9=14587 X 7 X 4=196
# samples 198
** MAII scorelog2(19/1458*10)=-2.93991939599599
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(8/196*10)=-1.29278174922785
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: NPEPPS [Title/Abstract] AND ARL17B [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointNPEPPS(45677105)-ARL17B(44377031), # samples:1
NPEPPS(45677105)-ARL17B(44388641), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneNPEPPS

GO:0071456

cellular response to hypoxia

21056661


check buttonFusion gene breakpoints across NPEPPS (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across ARL17B (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-A2-A0CX-01ANPEPPSchr17

45677105

+ARL17Bchr17

44377031

-
ChimerDB4BRCATCGA-A2-A0CX-01ANPEPPSchr17

45677105

+ARL17Bchr17

44388641

-


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Fusion Gene ORF analysis for NPEPPS-ARL17B

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
intron-3CDSENST00000525037ENST00000570618NPEPPSchr17

45677105

+ARL17Bchr17

44377031

-
intron-3CDSENST00000525037ENST00000434041NPEPPSchr17

45677105

+ARL17Bchr17

44377031

-
intron-intronENST00000525037ENST00000575698NPEPPSchr17

45677105

+ARL17Bchr17

44377031

-
intron-intronENST00000525037ENST00000575960NPEPPSchr17

45677105

+ARL17Bchr17

44377031

-
intron-intronENST00000525037ENST00000571246NPEPPSchr17

45677105

+ARL17Bchr17

44377031

-
intron-intronENST00000525037ENST00000450673NPEPPSchr17

45677105

+ARL17Bchr17

44377031

-
In-frameENST00000530173ENST00000570618NPEPPSchr17

45677105

+ARL17Bchr17

44377031

-
In-frameENST00000530173ENST00000434041NPEPPSchr17

45677105

+ARL17Bchr17

44377031

-
5CDS-intronENST00000530173ENST00000575698NPEPPSchr17

45677105

+ARL17Bchr17

44377031

-
5CDS-intronENST00000530173ENST00000575960NPEPPSchr17

45677105

+ARL17Bchr17

44377031

-
5CDS-intronENST00000530173ENST00000571246NPEPPSchr17

45677105

+ARL17Bchr17

44377031

-
5CDS-intronENST00000530173ENST00000450673NPEPPSchr17

45677105

+ARL17Bchr17

44377031

-
In-frameENST00000322157ENST00000570618NPEPPSchr17

45677105

+ARL17Bchr17

44377031

-
In-frameENST00000322157ENST00000434041NPEPPSchr17

45677105

+ARL17Bchr17

44377031

-
5CDS-intronENST00000322157ENST00000575698NPEPPSchr17

45677105

+ARL17Bchr17

44377031

-
5CDS-intronENST00000322157ENST00000575960NPEPPSchr17

45677105

+ARL17Bchr17

44377031

-
5CDS-intronENST00000322157ENST00000571246NPEPPSchr17

45677105

+ARL17Bchr17

44377031

-
5CDS-intronENST00000322157ENST00000450673NPEPPSchr17

45677105

+ARL17Bchr17

44377031

-
In-frameENST00000544660ENST00000570618NPEPPSchr17

45677105

+ARL17Bchr17

44377031

-
In-frameENST00000544660ENST00000434041NPEPPSchr17

45677105

+ARL17Bchr17

44377031

-
5CDS-intronENST00000544660ENST00000575698NPEPPSchr17

45677105

+ARL17Bchr17

44377031

-
5CDS-intronENST00000544660ENST00000575960NPEPPSchr17

45677105

+ARL17Bchr17

44377031

-
5CDS-intronENST00000544660ENST00000571246NPEPPSchr17

45677105

+ARL17Bchr17

44377031

-
5CDS-intronENST00000544660ENST00000450673NPEPPSchr17

45677105

+ARL17Bchr17

44377031

-
intron-intronENST00000525037ENST00000570618NPEPPSchr17

45677105

+ARL17Bchr17

44388641

-
intron-intronENST00000525037ENST00000434041NPEPPSchr17

45677105

+ARL17Bchr17

44388641

-
intron-intronENST00000525037ENST00000575698NPEPPSchr17

45677105

+ARL17Bchr17

44388641

-
intron-intronENST00000525037ENST00000575960NPEPPSchr17

45677105

+ARL17Bchr17

44388641

-
intron-intronENST00000525037ENST00000571246NPEPPSchr17

45677105

+ARL17Bchr17

44388641

-
intron-intronENST00000525037ENST00000450673NPEPPSchr17

45677105

+ARL17Bchr17

44388641

-
5CDS-intronENST00000530173ENST00000570618NPEPPSchr17

45677105

+ARL17Bchr17

44388641

-
5CDS-intronENST00000530173ENST00000434041NPEPPSchr17

45677105

+ARL17Bchr17

44388641

-
5CDS-intronENST00000530173ENST00000575698NPEPPSchr17

45677105

+ARL17Bchr17

44388641

-
5CDS-intronENST00000530173ENST00000575960NPEPPSchr17

45677105

+ARL17Bchr17

44388641

-
5CDS-intronENST00000530173ENST00000571246NPEPPSchr17

45677105

+ARL17Bchr17

44388641

-
5CDS-intronENST00000530173ENST00000450673NPEPPSchr17

45677105

+ARL17Bchr17

44388641

-
5CDS-intronENST00000322157ENST00000570618NPEPPSchr17

45677105

+ARL17Bchr17

44388641

-
5CDS-intronENST00000322157ENST00000434041NPEPPSchr17

45677105

+ARL17Bchr17

44388641

-
5CDS-intronENST00000322157ENST00000575698NPEPPSchr17

45677105

+ARL17Bchr17

44388641

-
5CDS-intronENST00000322157ENST00000575960NPEPPSchr17

45677105

+ARL17Bchr17

44388641

-
5CDS-intronENST00000322157ENST00000571246NPEPPSchr17

45677105

+ARL17Bchr17

44388641

-
5CDS-intronENST00000322157ENST00000450673NPEPPSchr17

45677105

+ARL17Bchr17

44388641

-
5CDS-intronENST00000544660ENST00000570618NPEPPSchr17

45677105

+ARL17Bchr17

44388641

-
5CDS-intronENST00000544660ENST00000434041NPEPPSchr17

45677105

+ARL17Bchr17

44388641

-
5CDS-intronENST00000544660ENST00000575698NPEPPSchr17

45677105

+ARL17Bchr17

44388641

-
5CDS-intronENST00000544660ENST00000575960NPEPPSchr17

45677105

+ARL17Bchr17

44388641

-
5CDS-intronENST00000544660ENST00000571246NPEPPSchr17

45677105

+ARL17Bchr17

44388641

-
5CDS-intronENST00000544660ENST00000450673NPEPPSchr17

45677105

+ARL17Bchr17

44388641

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000530173NPEPPSchr1745677105+ENST00000570618ARL17Bchr1744377031-23931618301736568
ENST00000530173NPEPPSchr1745677105+ENST00000434041ARL17Bchr1744377031-20701618301736568
ENST00000322157NPEPPSchr1745677105+ENST00000570618ARL17Bchr1744377031-26121837661955629
ENST00000322157NPEPPSchr1745677105+ENST00000434041ARL17Bchr1744377031-22891837661955629
ENST00000544660NPEPPSchr1745677105+ENST00000570618ARL17Bchr1744377031-22411466131584523
ENST00000544660NPEPPSchr1745677105+ENST00000434041ARL17Bchr1744377031-19181466131584523

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000530173ENST00000570618NPEPPSchr1745677105+ARL17Bchr1744377031-0.0004633480.99953663
ENST00000530173ENST00000434041NPEPPSchr1745677105+ARL17Bchr1744377031-0.0006031250.9993969
ENST00000322157ENST00000570618NPEPPSchr1745677105+ARL17Bchr1744377031-0.0008043230.99919564
ENST00000322157ENST00000434041NPEPPSchr1745677105+ARL17Bchr1744377031-0.0010194180.9989806
ENST00000544660ENST00000570618NPEPPSchr1745677105+ARL17Bchr1744377031-0.0002679180.9997321
ENST00000544660ENST00000434041NPEPPSchr1745677105+ARL17Bchr1744377031-0.0003474270.9996526

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Fusion Genomic Features for NPEPPS-ARL17B


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for NPEPPS-ARL17B


check button Go to

FGviewer for the breakpoints of chr17:45677105-chr17:44377031

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
NPEPPS

P55786

.
FUNCTION: Aminopeptidase with broad substrate specificity for several peptides. Involved in proteolytic events essential for cell growth and viability. May act as regulator of neuropeptide activity. Plays a role in the antigen-processing pathway for MHC class I molecules. Involved in the N-terminal trimming of cytotoxic T-cell epitope precursors. Digests the poly-Q peptides found in many cellular proteins. Digests tau from normal brain more efficiently than tau from Alzheimer disease brain. {ECO:0000269|PubMed:10978616, ECO:0000269|PubMed:11062501, ECO:0000269|PubMed:17154549, ECO:0000269|PubMed:17318184, ECO:0000269|PubMed:19917696}.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNPEPPSchr17:45677105chr17:44377031ENST00000322157+1423316_320533.3333333333334920.0RegionSubstrate binding
TgeneARL17Bchr17:45677105chr17:44377031ENST0000043404125125_12886.33333333333333198.33333333333334Nucleotide bindingGTP
TgeneARL17Bchr17:45677105chr17:44377031ENST0000045067304125_1280178.0Nucleotide bindingGTP
TgeneARL17Bchr17:45677105chr17:44377031ENST000004506730424_310178.0Nucleotide bindingGTP
TgeneARL17Bchr17:45677105chr17:44377031ENST000004506730467_710178.0Nucleotide bindingGTP
TgeneARL17Bchr17:45677105chr17:44377031ENST0000057061825125_12886.33333333333333299.6666666666667Nucleotide bindingGTP

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNPEPPSchr17:45677105chr17:44377031ENST00000322157+1423726_730533.3333333333334920.0MotifNuclear localization signal
TgeneARL17Bchr17:45677105chr17:44377031ENST000004340412524_3186.33333333333333198.33333333333334Nucleotide bindingGTP
TgeneARL17Bchr17:45677105chr17:44377031ENST000004340412567_7186.33333333333333198.33333333333334Nucleotide bindingGTP
TgeneARL17Bchr17:45677105chr17:44377031ENST000005706182524_3186.33333333333333299.6666666666667Nucleotide bindingGTP
TgeneARL17Bchr17:45677105chr17:44377031ENST000005706182567_7186.33333333333333299.6666666666667Nucleotide bindingGTP


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Fusion Gene Sequence for NPEPPS-ARL17B


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000530173_ENST00000570618_TCGA-A2-A0CX-01A_NPEPPS_chr17_45677105_+_ARL17B_chr17_44377031_length(transcript)=2393nt_BP=1618nt
AAGTTACGGAAGAGTCAAGGCTGGGACCTCATGGCATCATTTTCCATGGATTGCTCTCCAAGTTTTTGTGTTCCTGGCCTTTGGAACCCC
TTCATCATATTCCGCAGCCGCTCCTCTCGCCGCCGCCTCCACAGCCTGGGCCTCGCCGCGATGCCGGAGAAGAGGCCCTTCGAGCGGCTG
CCTGCCGATGTCTCCCCCATCAACTACAGCCTTTGCCTCAAGCCCGACTTGCTGGACTTCACCTTCGAGGGCAAGCTGGAGGCCGCCGCC
CAGGTGAGGCAGGCGACTAATCAGATTGTGATGAATTGTGCTGATATTGATATTATTACAGCTTCATATGCACCAGAAGGAGATGAAGAA
ATACATGCTACAGGATTTAACTATCAGAATGAAGATGAAAAAGTCACCTTGTCTTTCCCTAGTACTCTGCAAACAGGTACGGGAACCTTA
AAGATAGATTTTGTTGGAGAGCTGAATGACAAAATGAAAGGTTTCTATAGAAGTAAATATACTACCCCTTCTGGAGAGGTGCGCTATGCT
GCTGTAACACAGTTTGAGGCTACTGATGCCCGAAGGGCTTTTCCTTGCTGGGATGAGCCTGCTATCAAAGCAACTTTTGATATCTCATTG
GTTGTTCCTAAAGACAGAGTAGCTTTATCAAACATGAATGTAATTGACCGGAAACCATACCCTGATGATGAAAATTTAGTGGAAGTGAAG
TTTGCCCGCACACCTGTTATGTCTACATATCTGGTGGCATTTGTTGTGGGTGAATATGACTTTGTAGAAACAAGGTCAAAAGATGGTGTG
TGTGTCCGTGTTTACACTCCTGTTGGCAAAGCAGAGCAAGGAAAATTTGCGTTAGAGGTTGCTGCTAAAACCTTGCCTTTTTATAAGGAC
TACTTCAATGTTCCTTATCCTCTACCTAAAATTGATCTCATTGCTATTGCAGACTTTGCAGCTGGTGCCATGGAGAACTGGGGCCTTGTT
ACTTATAGGGAGACTGCATTGCTTATTGATCCAAAAAATTCCTGTTCTTCATCCCGCCAGTGGGTTGCTCTGGTTGTGGGACATGAACTC
GCCCATCAATGGTTTGGAAATCTTGTTACTATGGAATGGTGGACTCATCTTTGGTTAAATGAAGGTTTTGCATCCTGGATTGAATATCTG
TGTGTAGACCACTGCTTCCCAGAGTATGATATTTGGACTCAGTTTGTTTCTGCTGATTACACCCGTGCCCAGGAGCTTGACGCCTTAGAT
AACAGCCATCCTATTGAAGTCAGTGTGGGCCATCCATCTGAGGTTGATGAGATATTTGATGCTATATCATATAGCAAAGGTGCATCTGTC
ATCCGAATGCTGCATGACTACATTGGGGATAAGGACTTTAAGAAAGGAATGAACATGTATTTAACCAAGTTCCAACAAAAGAATGCTGCC
ACAGAGGATCTCTGGGAAAGTTTAGAAAATGCTAGTGGTAAACCTATAGCAGCTGTGATGAATACCTGGACCAAACAAATGGGATTTCCC
CTCATTTATGTGGAAGCTGAACAGGTAGAAGATGACAGATTATTGAGGTTGTCCCAAAAGAAGTTCTGTGCTGGTGGGTCATATGTTGAG
CTATCAGCTTCCCAGTTTGCACAATTCATCAAGAAATTATGCGGGGTCACTGGCACAAATGATGAGGCATCTCCTGGAAGCTTAACTTCT
TATCCATCCCATCTCTTGGACAGATGATGCCAGTTAATTACTTTGAATGTCTCACAACAACAAACTGCAGTCTACAGCTTCCTAAAGTTC
AGCATGTTAACCTAACATAAAACACAGCAAGAATCTTGTTGCCTGAACTATTTTAAATTAAGGAGCCAGATCTTTTTAGTGAGGCTATCC
TGACAAGACTTGACCTAAACTTTGTTTTTATTGGTCATAACAGTCCAATTATATTATTGGCCAATTTTGTCCAATGGACAAGAAAAAAGC
AAAGTTGCCAGGTGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGCGGGCGGATCATCTGAGGTCGGGAGTTCGAGAC
CAGCCTGACCAATATGGAGAAACCCCGTCTCTACCAAAAATACAAAATTAGCTGTGCATGGTGGCCTATGCCTGTAATCCCAGCTACTTG
GGAGGCTGAGGCAGGAGAATCGCTGGAACCCGGGAGGCAGAGGTTGTATTGAGCCGAGATTGAGCCATTGCACTCCAGCCTGGGTGACAA
GAACAAAACTCCGTTTCAAAAACAAAAAAAGGAAGAAAAGAAAAAGAAAAAAGAAAAGTCAACGACACCATTATCTTGTCAAGATCAAAT

>In-frame_ENST00000530173_ENST00000570618_TCGA-A2-A0CX-01A_NPEPPS_chr17_45677105_+_ARL17B_chr17_44377031_length(amino acids)=568AA_start in transcript=30_stop in transcript=1736
MASFSMDCSPSFCVPGLWNPFIIFRSRSSRRRLHSLGLAAMPEKRPFERLPADVSPINYSLCLKPDLLDFTFEGKLEAAAQVRQATNQIV
MNCADIDIITASYAPEGDEEIHATGFNYQNEDEKVTLSFPSTLQTGTGTLKIDFVGELNDKMKGFYRSKYTTPSGEVRYAAVTQFEATDA
RRAFPCWDEPAIKATFDISLVVPKDRVALSNMNVIDRKPYPDDENLVEVKFARTPVMSTYLVAFVVGEYDFVETRSKDGVCVRVYTPVGK
AEQGKFALEVAAKTLPFYKDYFNVPYPLPKIDLIAIADFAAGAMENWGLVTYRETALLIDPKNSCSSSRQWVALVVGHELAHQWFGNLVT
MEWWTHLWLNEGFASWIEYLCVDHCFPEYDIWTQFVSADYTRAQELDALDNSHPIEVSVGHPSEVDEIFDAISYSKGASVIRMLHDYIGD
KDFKKGMNMYLTKFQQKNAATEDLWESLENASGKPIAAVMNTWTKQMGFPLIYVEAEQVEDDRLLRLSQKKFCAGGSYVELSASQFAQFI

--------------------------------------------------------------
>In-frame_ENST00000530173_ENST00000434041_TCGA-A2-A0CX-01A_NPEPPS_chr17_45677105_+_ARL17B_chr17_44377031_length(transcript)=2070nt_BP=1618nt
AAGTTACGGAAGAGTCAAGGCTGGGACCTCATGGCATCATTTTCCATGGATTGCTCTCCAAGTTTTTGTGTTCCTGGCCTTTGGAACCCC
TTCATCATATTCCGCAGCCGCTCCTCTCGCCGCCGCCTCCACAGCCTGGGCCTCGCCGCGATGCCGGAGAAGAGGCCCTTCGAGCGGCTG
CCTGCCGATGTCTCCCCCATCAACTACAGCCTTTGCCTCAAGCCCGACTTGCTGGACTTCACCTTCGAGGGCAAGCTGGAGGCCGCCGCC
CAGGTGAGGCAGGCGACTAATCAGATTGTGATGAATTGTGCTGATATTGATATTATTACAGCTTCATATGCACCAGAAGGAGATGAAGAA
ATACATGCTACAGGATTTAACTATCAGAATGAAGATGAAAAAGTCACCTTGTCTTTCCCTAGTACTCTGCAAACAGGTACGGGAACCTTA
AAGATAGATTTTGTTGGAGAGCTGAATGACAAAATGAAAGGTTTCTATAGAAGTAAATATACTACCCCTTCTGGAGAGGTGCGCTATGCT
GCTGTAACACAGTTTGAGGCTACTGATGCCCGAAGGGCTTTTCCTTGCTGGGATGAGCCTGCTATCAAAGCAACTTTTGATATCTCATTG
GTTGTTCCTAAAGACAGAGTAGCTTTATCAAACATGAATGTAATTGACCGGAAACCATACCCTGATGATGAAAATTTAGTGGAAGTGAAG
TTTGCCCGCACACCTGTTATGTCTACATATCTGGTGGCATTTGTTGTGGGTGAATATGACTTTGTAGAAACAAGGTCAAAAGATGGTGTG
TGTGTCCGTGTTTACACTCCTGTTGGCAAAGCAGAGCAAGGAAAATTTGCGTTAGAGGTTGCTGCTAAAACCTTGCCTTTTTATAAGGAC
TACTTCAATGTTCCTTATCCTCTACCTAAAATTGATCTCATTGCTATTGCAGACTTTGCAGCTGGTGCCATGGAGAACTGGGGCCTTGTT
ACTTATAGGGAGACTGCATTGCTTATTGATCCAAAAAATTCCTGTTCTTCATCCCGCCAGTGGGTTGCTCTGGTTGTGGGACATGAACTC
GCCCATCAATGGTTTGGAAATCTTGTTACTATGGAATGGTGGACTCATCTTTGGTTAAATGAAGGTTTTGCATCCTGGATTGAATATCTG
TGTGTAGACCACTGCTTCCCAGAGTATGATATTTGGACTCAGTTTGTTTCTGCTGATTACACCCGTGCCCAGGAGCTTGACGCCTTAGAT
AACAGCCATCCTATTGAAGTCAGTGTGGGCCATCCATCTGAGGTTGATGAGATATTTGATGCTATATCATATAGCAAAGGTGCATCTGTC
ATCCGAATGCTGCATGACTACATTGGGGATAAGGACTTTAAGAAAGGAATGAACATGTATTTAACCAAGTTCCAACAAAAGAATGCTGCC
ACAGAGGATCTCTGGGAAAGTTTAGAAAATGCTAGTGGTAAACCTATAGCAGCTGTGATGAATACCTGGACCAAACAAATGGGATTTCCC
CTCATTTATGTGGAAGCTGAACAGGTAGAAGATGACAGATTATTGAGGTTGTCCCAAAAGAAGTTCTGTGCTGGTGGGTCATATGTTGAG
CTATCAGCTTCCCAGTTTGCACAATTCATCAAGAAATTATGCGGGGTCACTGGCACAAATGATGAGGCATCTCCTGGAAGCTTAACTTCT
TATCCATCCCATCTCTTGGACAGATGATGCCAGTTAATTACTTTGAATAAATATGGGCAAAAGCTTATCATTATCAACAAATGAGAAGAA
AGAAACCCTATGCCAGGTAACACCAAAGCTTTGGCCCAGTGCCCTCTGTTGAAACATCCTAGGCTTTTTCTTTCCACTCCTATTACAACT
GATCTGATTTGGCCCCTTCACACTTCACTCCTAGATTTTGCTAGACCTTTCTATTTTGTCTCCCTGAATTAAGCTTTTCCTTTTGGACAC
TTTACATATGGATTCTAAAACAATCCTCTGCATGTCTACACTTGCACATAATGCAAAAAACAAAATAAAATAATCTTCCTGTTTTGATCA

>In-frame_ENST00000530173_ENST00000434041_TCGA-A2-A0CX-01A_NPEPPS_chr17_45677105_+_ARL17B_chr17_44377031_length(amino acids)=568AA_start in transcript=30_stop in transcript=1736
MASFSMDCSPSFCVPGLWNPFIIFRSRSSRRRLHSLGLAAMPEKRPFERLPADVSPINYSLCLKPDLLDFTFEGKLEAAAQVRQATNQIV
MNCADIDIITASYAPEGDEEIHATGFNYQNEDEKVTLSFPSTLQTGTGTLKIDFVGELNDKMKGFYRSKYTTPSGEVRYAAVTQFEATDA
RRAFPCWDEPAIKATFDISLVVPKDRVALSNMNVIDRKPYPDDENLVEVKFARTPVMSTYLVAFVVGEYDFVETRSKDGVCVRVYTPVGK
AEQGKFALEVAAKTLPFYKDYFNVPYPLPKIDLIAIADFAAGAMENWGLVTYRETALLIDPKNSCSSSRQWVALVVGHELAHQWFGNLVT
MEWWTHLWLNEGFASWIEYLCVDHCFPEYDIWTQFVSADYTRAQELDALDNSHPIEVSVGHPSEVDEIFDAISYSKGASVIRMLHDYIGD
KDFKKGMNMYLTKFQQKNAATEDLWESLENASGKPIAAVMNTWTKQMGFPLIYVEAEQVEDDRLLRLSQKKFCAGGSYVELSASQFAQFI

--------------------------------------------------------------
>In-frame_ENST00000322157_ENST00000570618_TCGA-A2-A0CX-01A_NPEPPS_chr17_45677105_+_ARL17B_chr17_44377031_length(transcript)=2612nt_BP=1837nt
GGGCGCGCCCGGCCGGCGGGGCCGCGCACGCAGCCGCCGCCACCACTTCCCCCTCTCCCTCCCTCCTTGCGGGCCCTCCTCCCCTTCCCT
CCCCTCCGCCCCCTTCCCCGTAGGCAGCCCGCCCGCCAGTCCGCCCGCACCGCCTCCTTCCCAGCCCCTAGCGCTCCGGCTGGGTCTCTC
CCCCGCCCCCCAGGCTCCCCCGGTCGCTCTCCTCCGGCGGTCGCCCGCGCTCGGTGGATGTGGCTGGCAGCTGCCGCCCCCTCCCTCGCT
CGCCGCCTGCTCTTCCTCGGCCCTCCGCCTCCTCCCCTCCTCCTTCTCGTCTTCAGCCGCTCCTCTCGCCGCCGCCTCCACAGCCTGGGC
CTCGCCGCGATGCCGGAGAAGAGGCCCTTCGAGCGGCTGCCTGCCGATGTCTCCCCCATCAACTACAGCCTTTGCCTCAAGCCCGACTTG
CTGGACTTCACCTTCGAGGGCAAGCTGGAGGCCGCCGCCCAGGTGAGGCAGGCGACTAATCAGATTGTGATGAATTGTGCTGATATTGAT
ATTATTACAGCTTCATATGCACCAGAAGGAGATGAAGAAATACATGCTACAGGATTTAACTATCAGAATGAAGATGAAAAAGTCACCTTG
TCTTTCCCTAGTACTCTGCAAACAGGTACGGGAACCTTAAAGATAGATTTTGTTGGAGAGCTGAATGACAAAATGAAAGGTTTCTATAGA
AGTAAATATACTACCCCTTCTGGAGAGGTGCGCTATGCTGCTGTAACACAGTTTGAGGCTACTGATGCCCGAAGGGCTTTTCCTTGCTGG
GATGAGCCTGCTATCAAAGCAACTTTTGATATCTCATTGGTTGTTCCTAAAGACAGAGTAGCTTTATCAAACATGAATGTAATTGACCGG
AAACCATACCCTGATGATGAAAATTTAGTGGAAGTGAAGTTTGCCCGCACACCTGTTATGTCTACATATCTGGTGGCATTTGTTGTGGGT
GAATATGACTTTGTAGAAACAAGGTCAAAAGATGGTGTGTGTGTCCGTGTTTACACTCCTGTTGGCAAAGCAGAGCAAGGAAAATTTGCG
TTAGAGGTTGCTGCTAAAACCTTGCCTTTTTATAAGGACTACTTCAATGTTCCTTATCCTCTACCTAAAATTGATCTCATTGCTATTGCA
GACTTTGCAGCTGGTGCCATGGAGAACTGGGGCCTTGTTACTTATAGGGAGACTGCATTGCTTATTGATCCAAAAAATTCCTGTTCTTCA
TCCCGCCAGTGGGTTGCTCTGGTTGTGGGACATGAACTCGCCCATCAATGGTTTGGAAATCTTGTTACTATGGAATGGTGGACTCATCTT
TGGTTAAATGAAGGTTTTGCATCCTGGATTGAATATCTGTGTGTAGACCACTGCTTCCCAGAGTATGATATTTGGACTCAGTTTGTTTCT
GCTGATTACACCCGTGCCCAGGAGCTTGACGCCTTAGATAACAGCCATCCTATTGAAGTCAGTGTGGGCCATCCATCTGAGGTTGATGAG
ATATTTGATGCTATATCATATAGCAAAGGTGCATCTGTCATCCGAATGCTGCATGACTACATTGGGGATAAGGACTTTAAGAAAGGAATG
AACATGTATTTAACCAAGTTCCAACAAAAGAATGCTGCCACAGAGGATCTCTGGGAAAGTTTAGAAAATGCTAGTGGTAAACCTATAGCA
GCTGTGATGAATACCTGGACCAAACAAATGGGATTTCCCCTCATTTATGTGGAAGCTGAACAGGTAGAAGATGACAGATTATTGAGGTTG
TCCCAAAAGAAGTTCTGTGCTGGTGGGTCATATGTTGAGCTATCAGCTTCCCAGTTTGCACAATTCATCAAGAAATTATGCGGGGTCACT
GGCACAAATGATGAGGCATCTCCTGGAAGCTTAACTTCTTATCCATCCCATCTCTTGGACAGATGATGCCAGTTAATTACTTTGAATGTC
TCACAACAACAAACTGCAGTCTACAGCTTCCTAAAGTTCAGCATGTTAACCTAACATAAAACACAGCAAGAATCTTGTTGCCTGAACTAT
TTTAAATTAAGGAGCCAGATCTTTTTAGTGAGGCTATCCTGACAAGACTTGACCTAAACTTTGTTTTTATTGGTCATAACAGTCCAATTA
TATTATTGGCCAATTTTGTCCAATGGACAAGAAAAAAGCAAAGTTGCCAGGTGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGG
CCAAGGCGGGCGGATCATCTGAGGTCGGGAGTTCGAGACCAGCCTGACCAATATGGAGAAACCCCGTCTCTACCAAAAATACAAAATTAG
CTGTGCATGGTGGCCTATGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATCGCTGGAACCCGGGAGGCAGAGGTTGTATTG
AGCCGAGATTGAGCCATTGCACTCCAGCCTGGGTGACAAGAACAAAACTCCGTTTCAAAAACAAAAAAAGGAAGAAAAGAAAAAGAAAAA
AGAAAAGTCAACGACACCATTATCTTGTCAAGATCAAATGGTTTTATTATTGTGGCAGAAGCGAGAAAATTTTGTTTATTAAAAAAAAAA

>In-frame_ENST00000322157_ENST00000570618_TCGA-A2-A0CX-01A_NPEPPS_chr17_45677105_+_ARL17B_chr17_44377031_length(amino acids)=629AA_start in transcript=66_stop in transcript=1955
MRALLPFPPLRPLPRRQPARQSARTASFPAPSAPAGSLPRPPGSPGRSPPAVARARWMWLAAAAPSLARRLLFLGPPPPPLLLLVFSRSS
RRRLHSLGLAAMPEKRPFERLPADVSPINYSLCLKPDLLDFTFEGKLEAAAQVRQATNQIVMNCADIDIITASYAPEGDEEIHATGFNYQ
NEDEKVTLSFPSTLQTGTGTLKIDFVGELNDKMKGFYRSKYTTPSGEVRYAAVTQFEATDARRAFPCWDEPAIKATFDISLVVPKDRVAL
SNMNVIDRKPYPDDENLVEVKFARTPVMSTYLVAFVVGEYDFVETRSKDGVCVRVYTPVGKAEQGKFALEVAAKTLPFYKDYFNVPYPLP
KIDLIAIADFAAGAMENWGLVTYRETALLIDPKNSCSSSRQWVALVVGHELAHQWFGNLVTMEWWTHLWLNEGFASWIEYLCVDHCFPEY
DIWTQFVSADYTRAQELDALDNSHPIEVSVGHPSEVDEIFDAISYSKGASVIRMLHDYIGDKDFKKGMNMYLTKFQQKNAATEDLWESLE

--------------------------------------------------------------
>In-frame_ENST00000322157_ENST00000434041_TCGA-A2-A0CX-01A_NPEPPS_chr17_45677105_+_ARL17B_chr17_44377031_length(transcript)=2289nt_BP=1837nt
GGGCGCGCCCGGCCGGCGGGGCCGCGCACGCAGCCGCCGCCACCACTTCCCCCTCTCCCTCCCTCCTTGCGGGCCCTCCTCCCCTTCCCT
CCCCTCCGCCCCCTTCCCCGTAGGCAGCCCGCCCGCCAGTCCGCCCGCACCGCCTCCTTCCCAGCCCCTAGCGCTCCGGCTGGGTCTCTC
CCCCGCCCCCCAGGCTCCCCCGGTCGCTCTCCTCCGGCGGTCGCCCGCGCTCGGTGGATGTGGCTGGCAGCTGCCGCCCCCTCCCTCGCT
CGCCGCCTGCTCTTCCTCGGCCCTCCGCCTCCTCCCCTCCTCCTTCTCGTCTTCAGCCGCTCCTCTCGCCGCCGCCTCCACAGCCTGGGC
CTCGCCGCGATGCCGGAGAAGAGGCCCTTCGAGCGGCTGCCTGCCGATGTCTCCCCCATCAACTACAGCCTTTGCCTCAAGCCCGACTTG
CTGGACTTCACCTTCGAGGGCAAGCTGGAGGCCGCCGCCCAGGTGAGGCAGGCGACTAATCAGATTGTGATGAATTGTGCTGATATTGAT
ATTATTACAGCTTCATATGCACCAGAAGGAGATGAAGAAATACATGCTACAGGATTTAACTATCAGAATGAAGATGAAAAAGTCACCTTG
TCTTTCCCTAGTACTCTGCAAACAGGTACGGGAACCTTAAAGATAGATTTTGTTGGAGAGCTGAATGACAAAATGAAAGGTTTCTATAGA
AGTAAATATACTACCCCTTCTGGAGAGGTGCGCTATGCTGCTGTAACACAGTTTGAGGCTACTGATGCCCGAAGGGCTTTTCCTTGCTGG
GATGAGCCTGCTATCAAAGCAACTTTTGATATCTCATTGGTTGTTCCTAAAGACAGAGTAGCTTTATCAAACATGAATGTAATTGACCGG
AAACCATACCCTGATGATGAAAATTTAGTGGAAGTGAAGTTTGCCCGCACACCTGTTATGTCTACATATCTGGTGGCATTTGTTGTGGGT
GAATATGACTTTGTAGAAACAAGGTCAAAAGATGGTGTGTGTGTCCGTGTTTACACTCCTGTTGGCAAAGCAGAGCAAGGAAAATTTGCG
TTAGAGGTTGCTGCTAAAACCTTGCCTTTTTATAAGGACTACTTCAATGTTCCTTATCCTCTACCTAAAATTGATCTCATTGCTATTGCA
GACTTTGCAGCTGGTGCCATGGAGAACTGGGGCCTTGTTACTTATAGGGAGACTGCATTGCTTATTGATCCAAAAAATTCCTGTTCTTCA
TCCCGCCAGTGGGTTGCTCTGGTTGTGGGACATGAACTCGCCCATCAATGGTTTGGAAATCTTGTTACTATGGAATGGTGGACTCATCTT
TGGTTAAATGAAGGTTTTGCATCCTGGATTGAATATCTGTGTGTAGACCACTGCTTCCCAGAGTATGATATTTGGACTCAGTTTGTTTCT
GCTGATTACACCCGTGCCCAGGAGCTTGACGCCTTAGATAACAGCCATCCTATTGAAGTCAGTGTGGGCCATCCATCTGAGGTTGATGAG
ATATTTGATGCTATATCATATAGCAAAGGTGCATCTGTCATCCGAATGCTGCATGACTACATTGGGGATAAGGACTTTAAGAAAGGAATG
AACATGTATTTAACCAAGTTCCAACAAAAGAATGCTGCCACAGAGGATCTCTGGGAAAGTTTAGAAAATGCTAGTGGTAAACCTATAGCA
GCTGTGATGAATACCTGGACCAAACAAATGGGATTTCCCCTCATTTATGTGGAAGCTGAACAGGTAGAAGATGACAGATTATTGAGGTTG
TCCCAAAAGAAGTTCTGTGCTGGTGGGTCATATGTTGAGCTATCAGCTTCCCAGTTTGCACAATTCATCAAGAAATTATGCGGGGTCACT
GGCACAAATGATGAGGCATCTCCTGGAAGCTTAACTTCTTATCCATCCCATCTCTTGGACAGATGATGCCAGTTAATTACTTTGAATAAA
TATGGGCAAAAGCTTATCATTATCAACAAATGAGAAGAAAGAAACCCTATGCCAGGTAACACCAAAGCTTTGGCCCAGTGCCCTCTGTTG
AAACATCCTAGGCTTTTTCTTTCCACTCCTATTACAACTGATCTGATTTGGCCCCTTCACACTTCACTCCTAGATTTTGCTAGACCTTTC
TATTTTGTCTCCCTGAATTAAGCTTTTCCTTTTGGACACTTTACATATGGATTCTAAAACAATCCTCTGCATGTCTACACTTGCACATAA

>In-frame_ENST00000322157_ENST00000434041_TCGA-A2-A0CX-01A_NPEPPS_chr17_45677105_+_ARL17B_chr17_44377031_length(amino acids)=629AA_start in transcript=66_stop in transcript=1955
MRALLPFPPLRPLPRRQPARQSARTASFPAPSAPAGSLPRPPGSPGRSPPAVARARWMWLAAAAPSLARRLLFLGPPPPPLLLLVFSRSS
RRRLHSLGLAAMPEKRPFERLPADVSPINYSLCLKPDLLDFTFEGKLEAAAQVRQATNQIVMNCADIDIITASYAPEGDEEIHATGFNYQ
NEDEKVTLSFPSTLQTGTGTLKIDFVGELNDKMKGFYRSKYTTPSGEVRYAAVTQFEATDARRAFPCWDEPAIKATFDISLVVPKDRVAL
SNMNVIDRKPYPDDENLVEVKFARTPVMSTYLVAFVVGEYDFVETRSKDGVCVRVYTPVGKAEQGKFALEVAAKTLPFYKDYFNVPYPLP
KIDLIAIADFAAGAMENWGLVTYRETALLIDPKNSCSSSRQWVALVVGHELAHQWFGNLVTMEWWTHLWLNEGFASWIEYLCVDHCFPEY
DIWTQFVSADYTRAQELDALDNSHPIEVSVGHPSEVDEIFDAISYSKGASVIRMLHDYIGDKDFKKGMNMYLTKFQQKNAATEDLWESLE

--------------------------------------------------------------
>In-frame_ENST00000544660_ENST00000570618_TCGA-A2-A0CX-01A_NPEPPS_chr17_45677105_+_ARL17B_chr17_44377031_length(transcript)=2241nt_BP=1466nt
CCTCGCTCGCCGCCTGCTCTTCCTCGGCCCTCCGCCTCCTCCCCTCCTCCTTCTCGTCTTCAGCCGCTCCTCTCGCCGCCGCCTCCACAG
CCTGGGCCTCGCCGCGATGCCGGAGAAGAGGCCCTTCGAGCGGCTGCCTGCCGATGTCTCCCCCATCAACTACAGCCTTTGCCTCAAGCC
CGACTTGCTGGACTTCACCTTCGAGGGCAAGCTGGAGGCCGCCGCCCAGGTGAGGCAGGCGACTAATCAGATTGTGATGAATTGTGCTGA
TATTGATATTATTACAGCTTCATATGCACCAGAAGGAGATGAAGAAATACATGCTACAGGATTTAACTATCAGAATGAAGATGAAAAAGT
CACCTTGTCTTTCCCTAGTACTCTGCAAACAGGTACGGGAACCTTAAAGATAGATTTTGTTGGAGAGCTGAATGACAAAATGAAAGGTTT
CTATAGAAGTAAATATACTACCCCTTCTGGAGAGGTGCGCTATGCTGCTGTAACACAGTTTGAGAATGTAATTGACCGGAAACCATACCC
TGATGATGAAAATTTAGTGGAAGTGAAGTTTGCCCGCACACCTGTTATGTCTACATATCTGGTGGCATTTGTTGTGGGTGAATATGACTT
TGTAGAAACAAGGTCAAAAGATGGTGTGTGTGTCCGTGTTTACACTCCTGTTGGCAAAGCAGAGCAAGGAAAATTTGCGTTAGAGGTTGC
TGCTAAAACCTTGCCTTTTTATAAGGACTACTTCAATGTTCCTTATCCTCTACCTAAAATTGATCTCATTGCTATTGCAGACTTTGCAGC
TGGTGCCATGGAGAACTGGGGCCTTGTTACTTATAGGGAGACTGCATTGCTTATTGATCCAAAAAATTCCTGTTCTTCATCCCGCCAGTG
GGTTGCTCTGGTTGTGGGACATGAACTCGCCCATCAATGGTTTGGAAATCTTGTTACTATGGAATGGTGGACTCATCTTTGGTTAAATGA
AGGTTTTGCATCCTGGATTGAATATCTGTGTGTAGACCACTGCTTCCCAGAGTATGATATTTGGACTCAGTTTGTTTCTGCTGATTACAC
CCGTGCCCAGGAGCTTGACGCCTTAGATAACAGCCATCCTATTGAAGTCAGTGTGGGCCATCCATCTGAGGTTGATGAGATATTTGATGC
TATATCATATAGCAAAGGTGCATCTGTCATCCGAATGCTGCATGACTACATTGGGGATAAGGACTTTAAGAAAGGAATGAACATGTATTT
AACCAAGTTCCAACAAAAGAATGCTGCCACAGAGGATCTCTGGGAAAGTTTAGAAAATGCTAGTGGTAAACCTATAGCAGCTGTGATGAA
TACCTGGACCAAACAAATGGGATTTCCCCTCATTTATGTGGAAGCTGAACAGGTAGAAGATGACAGATTATTGAGGTTGTCCCAAAAGAA
GTTCTGTGCTGGTGGGTCATATGTTGAGCTATCAGCTTCCCAGTTTGCACAATTCATCAAGAAATTATGCGGGGTCACTGGCACAAATGA
TGAGGCATCTCCTGGAAGCTTAACTTCTTATCCATCCCATCTCTTGGACAGATGATGCCAGTTAATTACTTTGAATGTCTCACAACAACA
AACTGCAGTCTACAGCTTCCTAAAGTTCAGCATGTTAACCTAACATAAAACACAGCAAGAATCTTGTTGCCTGAACTATTTTAAATTAAG
GAGCCAGATCTTTTTAGTGAGGCTATCCTGACAAGACTTGACCTAAACTTTGTTTTTATTGGTCATAACAGTCCAATTATATTATTGGCC
AATTTTGTCCAATGGACAAGAAAAAAGCAAAGTTGCCAGGTGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGCGGGC
GGATCATCTGAGGTCGGGAGTTCGAGACCAGCCTGACCAATATGGAGAAACCCCGTCTCTACCAAAAATACAAAATTAGCTGTGCATGGT
GGCCTATGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATCGCTGGAACCCGGGAGGCAGAGGTTGTATTGAGCCGAGATTG
AGCCATTGCACTCCAGCCTGGGTGACAAGAACAAAACTCCGTTTCAAAAACAAAAAAAGGAAGAAAAGAAAAAGAAAAAAGAAAAGTCAA

>In-frame_ENST00000544660_ENST00000570618_TCGA-A2-A0CX-01A_NPEPPS_chr17_45677105_+_ARL17B_chr17_44377031_length(amino acids)=523AA_start in transcript=13_stop in transcript=1584
MLFLGPPPPPLLLLVFSRSSRRRLHSLGLAAMPEKRPFERLPADVSPINYSLCLKPDLLDFTFEGKLEAAAQVRQATNQIVMNCADIDII
TASYAPEGDEEIHATGFNYQNEDEKVTLSFPSTLQTGTGTLKIDFVGELNDKMKGFYRSKYTTPSGEVRYAAVTQFENVIDRKPYPDDEN
LVEVKFARTPVMSTYLVAFVVGEYDFVETRSKDGVCVRVYTPVGKAEQGKFALEVAAKTLPFYKDYFNVPYPLPKIDLIAIADFAAGAME
NWGLVTYRETALLIDPKNSCSSSRQWVALVVGHELAHQWFGNLVTMEWWTHLWLNEGFASWIEYLCVDHCFPEYDIWTQFVSADYTRAQE
LDALDNSHPIEVSVGHPSEVDEIFDAISYSKGASVIRMLHDYIGDKDFKKGMNMYLTKFQQKNAATEDLWESLENASGKPIAAVMNTWTK

--------------------------------------------------------------
>In-frame_ENST00000544660_ENST00000434041_TCGA-A2-A0CX-01A_NPEPPS_chr17_45677105_+_ARL17B_chr17_44377031_length(transcript)=1918nt_BP=1466nt
CCTCGCTCGCCGCCTGCTCTTCCTCGGCCCTCCGCCTCCTCCCCTCCTCCTTCTCGTCTTCAGCCGCTCCTCTCGCCGCCGCCTCCACAG
CCTGGGCCTCGCCGCGATGCCGGAGAAGAGGCCCTTCGAGCGGCTGCCTGCCGATGTCTCCCCCATCAACTACAGCCTTTGCCTCAAGCC
CGACTTGCTGGACTTCACCTTCGAGGGCAAGCTGGAGGCCGCCGCCCAGGTGAGGCAGGCGACTAATCAGATTGTGATGAATTGTGCTGA
TATTGATATTATTACAGCTTCATATGCACCAGAAGGAGATGAAGAAATACATGCTACAGGATTTAACTATCAGAATGAAGATGAAAAAGT
CACCTTGTCTTTCCCTAGTACTCTGCAAACAGGTACGGGAACCTTAAAGATAGATTTTGTTGGAGAGCTGAATGACAAAATGAAAGGTTT
CTATAGAAGTAAATATACTACCCCTTCTGGAGAGGTGCGCTATGCTGCTGTAACACAGTTTGAGAATGTAATTGACCGGAAACCATACCC
TGATGATGAAAATTTAGTGGAAGTGAAGTTTGCCCGCACACCTGTTATGTCTACATATCTGGTGGCATTTGTTGTGGGTGAATATGACTT
TGTAGAAACAAGGTCAAAAGATGGTGTGTGTGTCCGTGTTTACACTCCTGTTGGCAAAGCAGAGCAAGGAAAATTTGCGTTAGAGGTTGC
TGCTAAAACCTTGCCTTTTTATAAGGACTACTTCAATGTTCCTTATCCTCTACCTAAAATTGATCTCATTGCTATTGCAGACTTTGCAGC
TGGTGCCATGGAGAACTGGGGCCTTGTTACTTATAGGGAGACTGCATTGCTTATTGATCCAAAAAATTCCTGTTCTTCATCCCGCCAGTG
GGTTGCTCTGGTTGTGGGACATGAACTCGCCCATCAATGGTTTGGAAATCTTGTTACTATGGAATGGTGGACTCATCTTTGGTTAAATGA
AGGTTTTGCATCCTGGATTGAATATCTGTGTGTAGACCACTGCTTCCCAGAGTATGATATTTGGACTCAGTTTGTTTCTGCTGATTACAC
CCGTGCCCAGGAGCTTGACGCCTTAGATAACAGCCATCCTATTGAAGTCAGTGTGGGCCATCCATCTGAGGTTGATGAGATATTTGATGC
TATATCATATAGCAAAGGTGCATCTGTCATCCGAATGCTGCATGACTACATTGGGGATAAGGACTTTAAGAAAGGAATGAACATGTATTT
AACCAAGTTCCAACAAAAGAATGCTGCCACAGAGGATCTCTGGGAAAGTTTAGAAAATGCTAGTGGTAAACCTATAGCAGCTGTGATGAA
TACCTGGACCAAACAAATGGGATTTCCCCTCATTTATGTGGAAGCTGAACAGGTAGAAGATGACAGATTATTGAGGTTGTCCCAAAAGAA
GTTCTGTGCTGGTGGGTCATATGTTGAGCTATCAGCTTCCCAGTTTGCACAATTCATCAAGAAATTATGCGGGGTCACTGGCACAAATGA
TGAGGCATCTCCTGGAAGCTTAACTTCTTATCCATCCCATCTCTTGGACAGATGATGCCAGTTAATTACTTTGAATAAATATGGGCAAAA
GCTTATCATTATCAACAAATGAGAAGAAAGAAACCCTATGCCAGGTAACACCAAAGCTTTGGCCCAGTGCCCTCTGTTGAAACATCCTAG
GCTTTTTCTTTCCACTCCTATTACAACTGATCTGATTTGGCCCCTTCACACTTCACTCCTAGATTTTGCTAGACCTTTCTATTTTGTCTC
CCTGAATTAAGCTTTTCCTTTTGGACACTTTACATATGGATTCTAAAACAATCCTCTGCATGTCTACACTTGCACATAATGCAAAAAACA

>In-frame_ENST00000544660_ENST00000434041_TCGA-A2-A0CX-01A_NPEPPS_chr17_45677105_+_ARL17B_chr17_44377031_length(amino acids)=523AA_start in transcript=13_stop in transcript=1584
MLFLGPPPPPLLLLVFSRSSRRRLHSLGLAAMPEKRPFERLPADVSPINYSLCLKPDLLDFTFEGKLEAAAQVRQATNQIVMNCADIDII
TASYAPEGDEEIHATGFNYQNEDEKVTLSFPSTLQTGTGTLKIDFVGELNDKMKGFYRSKYTTPSGEVRYAAVTQFENVIDRKPYPDDEN
LVEVKFARTPVMSTYLVAFVVGEYDFVETRSKDGVCVRVYTPVGKAEQGKFALEVAAKTLPFYKDYFNVPYPLPKIDLIAIADFAAGAME
NWGLVTYRETALLIDPKNSCSSSRQWVALVVGHELAHQWFGNLVTMEWWTHLWLNEGFASWIEYLCVDHCFPEYDIWTQFVSADYTRAQE
LDALDNSHPIEVSVGHPSEVDEIFDAISYSKGASVIRMLHDYIGDKDFKKGMNMYLTKFQQKNAATEDLWESLENASGKPIAAVMNTWTK

--------------------------------------------------------------

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Fusion Gene PPI Analysis for NPEPPS-ARL17B


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for NPEPPS-ARL17B


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for NPEPPS-ARL17B


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource