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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:NRCAM-ACN9 (FusionGDB2 ID:59855)

Fusion Gene Summary for NRCAM-ACN9

check button Fusion gene summary
Fusion gene informationFusion gene name: NRCAM-ACN9
Fusion gene ID: 59855
HgeneTgene
Gene symbol

NRCAM

ACN9

Gene ID

4897

57001

Gene nameneuronal cell adhesion moleculesuccinate dehydrogenase complex assembly factor 3
Synonyms-ACN9|DC11|LYRM10|Sdh7
Cytomap

7q31.1

7q21.3

Type of geneprotein-codingprotein-coding
Descriptionneuronal cell adhesion moleculeNgCAM-related cell adhesion moleculeneuronal surface protein Bravosuccinate dehydrogenase assembly factor 3, mitochondrialACN9 homologSDH assembly factor 3protein ACN9 homolog, mitochondrial
Modification date2020031320200313
UniProtAcc

Q92823

.
Ensembl transtripts involved in fusion geneENST00000379028, ENST00000413765, 
ENST00000351718, ENST00000379024, 
ENST00000379022, ENST00000425651, 
ENST00000522550, 		ENST00000432641, 
ENST00000360382, ENST00000479853, 
Fusion gene scores* DoF score11 X 8 X 7=6164 X 2 X 4=32
# samples 124
** MAII scorelog2(12/616*10)=-2.35989594508638
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/32*10)=0.321928094887362
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: NRCAM [Title/Abstract] AND ACN9 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointNRCAM(107830089)-ACN9(96810324), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneNRCAM

GO:0045162

clustering of voltage-gated sodium channels

14602817


check buttonFusion gene breakpoints across NRCAM (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across ACN9 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4GBMTCGA-12-3652-01ANRCAMchr7

107830089

-ACN9chr7

96810324

+


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Fusion Gene ORF analysis for NRCAM-ACN9

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000379028ENST00000432641NRCAMchr7

107830089

-ACN9chr7

96810324

+
5CDS-3UTRENST00000379028ENST00000360382NRCAMchr7

107830089

-ACN9chr7

96810324

+
5CDS-3UTRENST00000379028ENST00000479853NRCAMchr7

107830089

-ACN9chr7

96810324

+
In-frameENST00000413765ENST00000432641NRCAMchr7

107830089

-ACN9chr7

96810324

+
5CDS-3UTRENST00000413765ENST00000360382NRCAMchr7

107830089

-ACN9chr7

96810324

+
5CDS-3UTRENST00000413765ENST00000479853NRCAMchr7

107830089

-ACN9chr7

96810324

+
In-frameENST00000351718ENST00000432641NRCAMchr7

107830089

-ACN9chr7

96810324

+
5CDS-3UTRENST00000351718ENST00000360382NRCAMchr7

107830089

-ACN9chr7

96810324

+
5CDS-3UTRENST00000351718ENST00000479853NRCAMchr7

107830089

-ACN9chr7

96810324

+
In-frameENST00000379024ENST00000432641NRCAMchr7

107830089

-ACN9chr7

96810324

+
5CDS-3UTRENST00000379024ENST00000360382NRCAMchr7

107830089

-ACN9chr7

96810324

+
5CDS-3UTRENST00000379024ENST00000479853NRCAMchr7

107830089

-ACN9chr7

96810324

+
In-frameENST00000379022ENST00000432641NRCAMchr7

107830089

-ACN9chr7

96810324

+
5CDS-3UTRENST00000379022ENST00000360382NRCAMchr7

107830089

-ACN9chr7

96810324

+
5CDS-3UTRENST00000379022ENST00000479853NRCAMchr7

107830089

-ACN9chr7

96810324

+
In-frameENST00000425651ENST00000432641NRCAMchr7

107830089

-ACN9chr7

96810324

+
5CDS-3UTRENST00000425651ENST00000360382NRCAMchr7

107830089

-ACN9chr7

96810324

+
5CDS-3UTRENST00000425651ENST00000479853NRCAMchr7

107830089

-ACN9chr7

96810324

+
intron-3CDSENST00000522550ENST00000432641NRCAMchr7

107830089

-ACN9chr7

96810324

+
intron-3UTRENST00000522550ENST00000360382NRCAMchr7

107830089

-ACN9chr7

96810324

+
intron-3UTRENST00000522550ENST00000479853NRCAMchr7

107830089

-ACN9chr7

96810324

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000379028NRCAMchr7107830089-ENST00000432641ACN9chr796810324+325825064712537688
ENST00000413765NRCAMchr7107830089-ENST00000432641ACN9chr796810324+320124494712480669
ENST00000351718NRCAMchr7107830089-ENST00000432641ACN9chr796810324+316724154282446672
ENST00000379024NRCAMchr7107830089-ENST00000432641ACN9chr796810324+314023884102419669
ENST00000379022NRCAMchr7107830089-ENST00000432641ACN9chr796810324+325825064712537688
ENST00000425651NRCAMchr7107830089-ENST00000432641ACN9chr796810324+2787203502066688

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000379028ENST00000432641NRCAMchr7107830089-ACN9chr796810324+0.0010850430.99891496
ENST00000413765ENST00000432641NRCAMchr7107830089-ACN9chr796810324+0.00100380.9989962
ENST00000351718ENST00000432641NRCAMchr7107830089-ACN9chr796810324+0.0003459470.99965405
ENST00000379024ENST00000432641NRCAMchr7107830089-ACN9chr796810324+0.0008679150.9991321
ENST00000379022ENST00000432641NRCAMchr7107830089-ACN9chr796810324+0.0012390820.99876094
ENST00000425651ENST00000432641NRCAMchr7107830089-ACN9chr796810324+0.0009805890.9990194

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Fusion Genomic Features for NRCAM-ACN9


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
NRCAMchr7107830088-ACN9chr796810323+0.155266790.84473324
NRCAMchr7107830088-ACN9chr796810323+0.155266790.84473324

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for NRCAM-ACN9


check button Go to

FGviewer for the breakpoints of chr7:107830089-chr7:96810324

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
NRCAM

Q92823

.
FUNCTION: Cell adhesion protein that is required for normal responses to cell-cell contacts in brain and in the peripheral nervous system. Plays a role in neurite outgrowth in response to contactin binding. Plays a role in mediating cell-cell contacts between Schwann cells and axons. Plays a role in the formation and maintenance of the nodes of Ranvier on myelinated axons. Nodes of Ranvier contain clustered sodium channels that are crucial for the saltatory propagation of action potentials along myelinated axons. During development, nodes of Ranvier are formed by the fusion of two heminodes. Required for normal clustering of sodium channels at heminodes; not required for the formation of mature nodes with normal sodium channel clusters. Required, together with GLDN, for maintaining NFASC and sodium channel clusters at mature nodes of Ranvier. {ECO:0000250|UniProtKB:Q810U4}.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNRCAMchr7:107830089chr7:96810324ENST00000351718-1828141_235662.33333333333341184.0DomainNote=Ig-like 2
HgeneNRCAMchr7:107830089chr7:96810324ENST00000351718-1828267_356662.33333333333341184.0DomainNote=Ig-like 3
HgeneNRCAMchr7:107830089chr7:96810324ENST00000351718-1828361_448662.33333333333341184.0DomainNote=Ig-like 4
HgeneNRCAMchr7:107830089chr7:96810324ENST00000351718-1828454_541662.33333333333341184.0DomainNote=Ig-like 5
HgeneNRCAMchr7:107830089chr7:96810324ENST00000351718-182846_134662.33333333333341184.0DomainNote=Ig-like 1
HgeneNRCAMchr7:107830089chr7:96810324ENST00000351718-1828545_632662.33333333333341184.0DomainNote=Ig-like 6
HgeneNRCAMchr7:107830089chr7:96810324ENST00000379024-1930141_235659.33333333333341193.0DomainNote=Ig-like 2
HgeneNRCAMchr7:107830089chr7:96810324ENST00000379024-1930267_356659.33333333333341193.0DomainNote=Ig-like 3
HgeneNRCAMchr7:107830089chr7:96810324ENST00000379024-1930361_448659.33333333333341193.0DomainNote=Ig-like 4
HgeneNRCAMchr7:107830089chr7:96810324ENST00000379024-1930454_541659.33333333333341193.0DomainNote=Ig-like 5
HgeneNRCAMchr7:107830089chr7:96810324ENST00000379024-193046_134659.33333333333341193.0DomainNote=Ig-like 1
HgeneNRCAMchr7:107830089chr7:96810324ENST00000379024-1930545_632659.33333333333341193.0DomainNote=Ig-like 6
HgeneNRCAMchr7:107830089chr7:96810324ENST00000379028-2033141_235678.33333333333341305.0DomainNote=Ig-like 2
HgeneNRCAMchr7:107830089chr7:96810324ENST00000379028-2033267_356678.33333333333341305.0DomainNote=Ig-like 3
HgeneNRCAMchr7:107830089chr7:96810324ENST00000379028-2033361_448678.33333333333341305.0DomainNote=Ig-like 4
HgeneNRCAMchr7:107830089chr7:96810324ENST00000379028-2033454_541678.33333333333341305.0DomainNote=Ig-like 5
HgeneNRCAMchr7:107830089chr7:96810324ENST00000379028-203346_134678.33333333333341305.0DomainNote=Ig-like 1
HgeneNRCAMchr7:107830089chr7:96810324ENST00000379028-2033545_632678.33333333333341305.0DomainNote=Ig-like 6
HgeneNRCAMchr7:107830089chr7:96810324ENST00000425651-1730141_235678.33333333333341305.0DomainNote=Ig-like 2
HgeneNRCAMchr7:107830089chr7:96810324ENST00000425651-1730267_356678.33333333333341305.0DomainNote=Ig-like 3
HgeneNRCAMchr7:107830089chr7:96810324ENST00000425651-1730361_448678.33333333333341305.0DomainNote=Ig-like 4
HgeneNRCAMchr7:107830089chr7:96810324ENST00000425651-1730454_541678.33333333333341305.0DomainNote=Ig-like 5
HgeneNRCAMchr7:107830089chr7:96810324ENST00000425651-173046_134678.33333333333341305.0DomainNote=Ig-like 1
HgeneNRCAMchr7:107830089chr7:96810324ENST00000425651-1730545_632678.33333333333341305.0DomainNote=Ig-like 6

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNRCAMchr7:107830089chr7:96810324ENST00000351718-18281064_1156662.33333333333341184.0DomainFibronectin type-III 5
HgeneNRCAMchr7:107830089chr7:96810324ENST00000351718-1828649_744662.33333333333341184.0DomainFibronectin type-III 1
HgeneNRCAMchr7:107830089chr7:96810324ENST00000351718-1828746_843662.33333333333341184.0DomainFibronectin type-III 2
HgeneNRCAMchr7:107830089chr7:96810324ENST00000351718-1828848_950662.33333333333341184.0DomainFibronectin type-III 3
HgeneNRCAMchr7:107830089chr7:96810324ENST00000351718-1828954_1051662.33333333333341184.0DomainFibronectin type-III 4
HgeneNRCAMchr7:107830089chr7:96810324ENST00000379024-19301064_1156659.33333333333341193.0DomainFibronectin type-III 5
HgeneNRCAMchr7:107830089chr7:96810324ENST00000379024-1930649_744659.33333333333341193.0DomainFibronectin type-III 1
HgeneNRCAMchr7:107830089chr7:96810324ENST00000379024-1930746_843659.33333333333341193.0DomainFibronectin type-III 2
HgeneNRCAMchr7:107830089chr7:96810324ENST00000379024-1930848_950659.33333333333341193.0DomainFibronectin type-III 3
HgeneNRCAMchr7:107830089chr7:96810324ENST00000379024-1930954_1051659.33333333333341193.0DomainFibronectin type-III 4
HgeneNRCAMchr7:107830089chr7:96810324ENST00000379028-20331064_1156678.33333333333341305.0DomainFibronectin type-III 5
HgeneNRCAMchr7:107830089chr7:96810324ENST00000379028-2033649_744678.33333333333341305.0DomainFibronectin type-III 1
HgeneNRCAMchr7:107830089chr7:96810324ENST00000379028-2033746_843678.33333333333341305.0DomainFibronectin type-III 2
HgeneNRCAMchr7:107830089chr7:96810324ENST00000379028-2033848_950678.33333333333341305.0DomainFibronectin type-III 3
HgeneNRCAMchr7:107830089chr7:96810324ENST00000379028-2033954_1051678.33333333333341305.0DomainFibronectin type-III 4
HgeneNRCAMchr7:107830089chr7:96810324ENST00000425651-17301064_1156678.33333333333341305.0DomainFibronectin type-III 5
HgeneNRCAMchr7:107830089chr7:96810324ENST00000425651-1730649_744678.33333333333341305.0DomainFibronectin type-III 1
HgeneNRCAMchr7:107830089chr7:96810324ENST00000425651-1730746_843678.33333333333341305.0DomainFibronectin type-III 2
HgeneNRCAMchr7:107830089chr7:96810324ENST00000425651-1730848_950678.33333333333341305.0DomainFibronectin type-III 3
HgeneNRCAMchr7:107830089chr7:96810324ENST00000425651-1730954_1051678.33333333333341305.0DomainFibronectin type-III 4
HgeneNRCAMchr7:107830089chr7:96810324ENST00000351718-18281191_1304662.33333333333341184.0Topological domainCytoplasmic
HgeneNRCAMchr7:107830089chr7:96810324ENST00000351718-182825_1167662.33333333333341184.0Topological domainExtracellular
HgeneNRCAMchr7:107830089chr7:96810324ENST00000379024-19301191_1304659.33333333333341193.0Topological domainCytoplasmic
HgeneNRCAMchr7:107830089chr7:96810324ENST00000379024-193025_1167659.33333333333341193.0Topological domainExtracellular
HgeneNRCAMchr7:107830089chr7:96810324ENST00000379028-20331191_1304678.33333333333341305.0Topological domainCytoplasmic
HgeneNRCAMchr7:107830089chr7:96810324ENST00000379028-203325_1167678.33333333333341305.0Topological domainExtracellular
HgeneNRCAMchr7:107830089chr7:96810324ENST00000425651-17301191_1304678.33333333333341305.0Topological domainCytoplasmic
HgeneNRCAMchr7:107830089chr7:96810324ENST00000425651-173025_1167678.33333333333341305.0Topological domainExtracellular
HgeneNRCAMchr7:107830089chr7:96810324ENST00000351718-18281168_1190662.33333333333341184.0TransmembraneHelical
HgeneNRCAMchr7:107830089chr7:96810324ENST00000379024-19301168_1190659.33333333333341193.0TransmembraneHelical
HgeneNRCAMchr7:107830089chr7:96810324ENST00000379028-20331168_1190678.33333333333341305.0TransmembraneHelical
HgeneNRCAMchr7:107830089chr7:96810324ENST00000425651-17301168_1190678.33333333333341305.0TransmembraneHelical


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Fusion Gene Sequence for NRCAM-ACN9


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000379028_ENST00000432641_TCGA-12-3652-01A_NRCAM_chr7_107830089_-_ACN9_chr7_96810324_length(transcript)=3258nt_BP=2506nt
CGCGCGGGCGCGGGGGACGGCGCAGGGGCCGCCTGGCTGGAGCAGCCAGAGGGGATAGCTTCGTCGAGAACGGAGGACACCGGCGGTCCA
GGGTCCTGGGCAGTCGCGCCAGAGCTGAGCGGAGGGCGCGGCGCGAGAACGAATCTTTGTGACATTCTCTCTCAGCATTCTTTATCCCCT
GTTTGCTGAAGACTTCGACAAAAGCTGGTCTTAGCTGTTGGCATTCTCCTGAGAAAAGGATAGCTTCAGAAATCAGAAAAACATTTGGGA
GGTGTCTAGCCCAGTGGACCTTCTGAAGAGCAATGCTAAGAAGACGTTTGGTTTAAAGAATTAAAAGGAAGAACAACTTAAGAGCTTCTT
CAAAGTTTCCCGCATGAAAATTACTTAAACGTTGCACACAACGTTTCACAAAATCTTTTGTGAAAGAAGAAAAGGAAATTCAGTGTGTGA
GTCTCAGCAGGAGTTAAGCTAATGCAGCTTAAAATAATGCCGAAAAAGAAGCGCTTATCTGCGGGCAGAGTGCCCCTGATTCTCTTCCTG
TGCCAGATGATTAGTGCACTGGAAGTACCTCTTGATCCAAAACTTCTTGAAGACTTGGTACAGCCTCCAACCATCACCCAACAGTCTCCA
AAAGATTACATTATTGACCCTCGGGAGAATATTGTAATCCAGTGTGAAGCCAAAGGGAAACCGCCCCCAAGCTTTTCCTGGACCCGTAAT
GGGACTCATTTTGACATCGATAAAGACCCTCTGGTCACCATGAAGCCTGGCACAGGAACGCTCATAATTAACATCATGAGCGAAGGGAAA
GCTGAGACCTATGAAGGAGTCTATCAGTGTACAGCAAGGAACGAACGCGGAGCTGCAGTTTCTAATAACATTGTTGTCCGCCCATCCAGA
TCACCATTGTGGACCAAAGAAAAACTTGAACCAATCACACTTCAAAGTGGTCAGTCTTTAGTACTTCCCTGCAGACCCCCAATTGGATTA
CCACCACCTATAATATTTTGGATGGATAATTCCTTTCAAAGACTTCCACAAAGTGAGAGAGTTTCTCAAGGTTTGAATGGGGACCTTTAT
TTTTCCAATGTCCTCCCAGAGGACACCCGCGAAGACTATATCTGTTATGCTAGATTTAATCATACTCAAACCATACAGCAGAAGCAACCT
ATTTCTGTGAAGGTGATTTCAGTGGATGAATTGAATGACACTATAGCTGCTAATTTGAGTGACACTGAGTTTTATGGTGCTAAATCAAGT
AGAGAGAGGCCACCAACATTTTTAACTCCAGAAGGCAATGCAAGTAACAAAGAGGAATTAAGAGGAAATGTGCTTTCACTGGAGTGCATT
GCAGAAGGACTGCCTACCCCAATTATTTACTGGGCAAAGGAAGATGGAATGCTACCCAAAAACAGGACAGTTTATAAGAACTTTGAGAAA
ACCTTGCAGATCATTCATGTTTCAGAAGCAGACTCTGGAAATTACCAATGTATAGCAAAAAACGCATTAGGAGCCATCCACCATACCATT
TCTGTTAGAGTTAAAGCGGCTCCATACTGGATCACAGCCCCTCAAAATCTTGTGCTGTCCCCAGGAGAGGATGGGACCTTGATCTGCAGA
GCTAATGGCAACCCCAAACCCAGAATTAGCTGGTTAACAAATGGAGTCCCAATAGAAATTGCCCCTGATGACCCCAGCAGAAAAATAGAT
GGCGATACCATTATTTTTTCAAATGTTCAAGAAAGATCAAGTGCAGTCTATCAGTGCAATGCCTCTAATGAATATGGATATTTACTGGCA
AACGCATTTGTAAATGTGCTGGCTGAGCCACCACGAATCCTCACACCTGCAAACACACTCTACCAGGTCATTGCAAACAGGCCTGCTTTA
CTAGACTGTGCCTTCTTTGGGTCTCCTCTCCCAACCATCGAGTGGTTTAAAGGAGCTAAAGGAAGTGCTCTTCATGAAGATATTTATGTT
TTACATGAAAATGGAACTTTGGAAATTCCTGTGGCCCAAAAGGACAGTACAGGAACTTATACGTGTGTTGCAAGGAATAAATTAGGGATG
GCGAAGAATGAAGTTCACTTAGAAATCAAAGATCCTACATGGATCGTTAAACAGCCCGAATATGCAGTTGTGCAAAGAGGGAGCATGGTG
TCCTTTGAATGCAAAGTGAAACATGATCACACCTTATCCCTCACTGTCCTGTGGCTGAAGGACAACAGGGAACTGCCCAGTGATGAAAGG
TTCACTGTTGACAAGGATCATCTAGTGGTAGCTGATGTCAGTGACGATGACAGCGGGACCTACACGTGTGTGGCCAACACCACTCTGGAC
AGCGTCTCCGCCAGCGCTGTGCTTAGCGTTGTTGCTCCTACTCCAACTCCAGCTCCCGTTTACGATGTCCCAAATCCTCCCTTTGACTTA
GAACTGACAGATCAACTTGACAAAAGTGTTCAGCTGTCATGGACCCCAGGCGATGACAACAATAGCCCCATTACAAGTGTATGCAACAGC
GTTATTGCAACAGGCTAACGAAAACAGACAAAATTCAACTGGAAAAGCATGTTTTGGCACCTTCCTCCCAGAAGAAAAACTTAATGACTT
TCGTGATGAACAAATTGGACAGTTGCAGGAGCTGATGCAAGAAGCCACAAAACCCAATAGGCAATTTAGTATTTCTGAGTCTATGAAACC
AAAATTTTAGTCTATACAACAAAGCTTAATAAGACATGCAAAAATTTAGAACCCCTACTTTAACTGTCATTGGTTTTTGAAATATATTTA
AGCTTTGAAAACACCTGTTATTAATGAAATACTCTTTTATTTTGGATATTATGATTGCAGTATATGGATCAAGATCACTAGTGACAATTG
AAAAAAACTATTGGAATAATAGCACTTGTATGAAATTCAGTTTTGGAACTAAACAGCAAATTTCTAGAATTTTGCTGAAAATGTTTTAAA
ATGCTATTCTCATCCAGCCATATTAGTCTTCTGGCTTTTCTTTAGCTTCATCAAATAAGCATGTTGTGATAATGATAGATGTACAATTCC
AACAAGGTTATTATTTTTTAAATACATTGTCATTCTGAACATTTTATCACTTCTAGTTTAATAATACATACATGATTTTTCTTCTGAATG
TCTCTTCTCCCTGCATCACTGTTCATTCACAATGAAAGGTTAGGAAGAAGCTTTAAAATTCACTATTTTACTATCAATCATTTGTATAAT

>In-frame_ENST00000379028_ENST00000432641_TCGA-12-3652-01A_NRCAM_chr7_107830089_-_ACN9_chr7_96810324_length(amino acids)=688AA_start in transcript=471_stop in transcript=2537
MQLKIMPKKKRLSAGRVPLILFLCQMISALEVPLDPKLLEDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDID
KDPLVTMKPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFW
MDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTF
LTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAA
PYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVL
AEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHL
EIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVADVSDDDSGTYTCVANTTLDSVSASAV

--------------------------------------------------------------
>In-frame_ENST00000413765_ENST00000432641_TCGA-12-3652-01A_NRCAM_chr7_107830089_-_ACN9_chr7_96810324_length(transcript)=3201nt_BP=2449nt
CGCGCGGGCGCGGGGGACGGCGCAGGGGCCGCCTGGCTGGAGCAGCCAGAGGGGATAGCTTCGTCGAGAACGGAGGACACCGGCGGTCCA
GGGTCCTGGGCAGTCGCGCCAGAGCTGAGCGGAGGGCGCGGCGCGAGAACGAATCTTTGTGACATTCTCTCTCAGCATTCTTTATCCCCT
GTTTGCTGAAGACTTCGACAAAAGCTGGTCTTAGCTGTTGGCATTCTCCTGAGAAAAGGATAGCTTCAGAAATCAGAAAAACATTTGGGA
GGTGTCTAGCCCAGTGGACCTTCTGAAGAGCAATGCTAAGAAGACGTTTGGTTTAAAGAATTAAAAGGAAGAACAACTTAAGAGCTTCTT
CAAAGTTTCCCGCATGAAAATTACTTAAACGTTGCACACAACGTTTCACAAAATCTTTTGTGAAAGAAGAAAAGGAAATTCAGTGTGTGA
GTCTCAGCAGGAGTTAAGCTAATGCAGCTTAAAATAATGCCGAAAAAGAAGCGCTTATCTGCGGGCAGAGTGCCCCTGATTCTCTTCCTG
TGCCAGATGATTAGTGCACTGGAAGTACCTCTTGATCAAAAATCTACTGAAGTAATGGTACAGCCTCCAACCATCACCCAACAGTCTCCA
AAAGATTACATTATTGACCCTCGGGAGAATATTGTAATCCAGTGTGAAGCCAAAGGGAAACCGCCCCCAAGCTTTTCCTGGACCCGTAAT
GGGACTCATTTTGACATCGATAAAGACCCTCTGGTCACCATGAAGCCTGGCACAGGAACGCTCATAATTAACATCATGAGCGAAGGGAAA
GCTGAGACCTATGAAGGAGTCTATCAGTGTACAGCAAGGAACGAACGCGGAGCTGCAGTTTCTAATAACATTGTTGTCCGCCCATCCAGA
TCACCATTGTGGACCAAAGAAAAACTTGAACCAATCACACTTCAAAGTGGTCAGTCTTTAGTACTTCCCTGCAGACCCCCAATTGGATTA
CCACCACCTATAATATTTTGGATGGATAATTCCTTTCAAAGACTTCCACAAAGTGAGAGAGTTTCTCAAGGTTTGAATGGGGACCTTTAT
TTTTCCAATGTCCTCCCAGAGGACACCCGCGAAGACTATATCTGTTATGCTAGATTTAATCATACTCAAACCATACAGCAGAAGCAACCT
ATTTCTGTGAAGGTGATTTCAGCTAAATCAAGTAGAGAGAGGCCACCAACATTTTTAACTCCAGAAGGCAATGCAAGTAACAAAGAGGAA
TTAAGAGGAAATGTGCTTTCACTGGAGTGCATTGCAGAAGGACTGCCTACCCCAATTATTTACTGGGCAAAGGAAGATGGAATGCTACCC
AAAAACAGGACAGTTTATAAGAACTTTGAGAAAACCTTGCAGATCATTCATGTTTCAGAAGCAGACTCTGGAAATTACCAATGTATAGCA
AAAAACGCATTAGGAGCCATCCACCATACCATTTCTGTTAGAGTTAAAGCGGCTCCATACTGGATCACAGCCCCTCAAAATCTTGTGCTG
TCCCCAGGAGAGGATGGGACCTTGATCTGCAGAGCTAATGGCAACCCCAAACCCAGAATTAGCTGGTTAACAAATGGAGTCCCAATAGAA
ATTGCCCCTGATGACCCCAGCAGAAAAATAGATGGCGATACCATTATTTTTTCAAATGTTCAAGAAAGATCAAGTGCAGTCTATCAGTGC
AATGCCTCTAATGAATATGGATATTTACTGGCAAACGCATTTGTAAATGTGCTGGCTGAGCCACCACGAATCCTCACACCTGCAAACACA
CTCTACCAGGTCATTGCAAACAGGCCTGCTTTACTAGACTGTGCCTTCTTTGGGTCTCCTCTCCCAACCATCGAGTGGTTTAAAGGAGCT
AAAGGAAGTGCTCTTCATGAAGATATTTATGTTTTACATGAAAATGGAACTTTGGAAATTCCTGTGGCCCAAAAGGACAGTACAGGAACT
TATACGTGTGTTGCAAGGAATAAATTAGGGATGGCGAAGAATGAAGTTCACTTAGAAATCAAAGATCCTACATGGATCGTTAAACAGCCC
GAATATGCAGTTGTGCAAAGAGGGAGCATGGTGTCCTTTGAATGCAAAGTGAAACATGATCACACCTTATCCCTCACTGTCCTGTGGCTG
AAGGACAACAGGGAACTGCCCAGTGATGAAAGGTTCACTGTTGACAAGGATCATCTAGTGGTAGCTGATGTCAGTGACGATGACAGCGGG
ACCTACACGTGTGTGGCCAACACCACTCTGGACAGCGTCTCCGCCAGCGCTGTGCTTAGCGTTGTTGCTCCTACTCCAACTCCAGCTCCC
GTTTACGATGTCCCAAATCCTCCCTTTGACTTAGAACTGACAGATCAACTTGACAAAAGTGTTCAGCTGTCATGGACCCCAGGCGATGAC
AACAATAGCCCCATTACAAGTGTATGCAACAGCGTTATTGCAACAGGCTAACGAAAACAGACAAAATTCAACTGGAAAAGCATGTTTTGG
CACCTTCCTCCCAGAAGAAAAACTTAATGACTTTCGTGATGAACAAATTGGACAGTTGCAGGAGCTGATGCAAGAAGCCACAAAACCCAA
TAGGCAATTTAGTATTTCTGAGTCTATGAAACCAAAATTTTAGTCTATACAACAAAGCTTAATAAGACATGCAAAAATTTAGAACCCCTA
CTTTAACTGTCATTGGTTTTTGAAATATATTTAAGCTTTGAAAACACCTGTTATTAATGAAATACTCTTTTATTTTGGATATTATGATTG
CAGTATATGGATCAAGATCACTAGTGACAATTGAAAAAAACTATTGGAATAATAGCACTTGTATGAAATTCAGTTTTGGAACTAAACAGC
AAATTTCTAGAATTTTGCTGAAAATGTTTTAAAATGCTATTCTCATCCAGCCATATTAGTCTTCTGGCTTTTCTTTAGCTTCATCAAATA
AGCATGTTGTGATAATGATAGATGTACAATTCCAACAAGGTTATTATTTTTTAAATACATTGTCATTCTGAACATTTTATCACTTCTAGT
TTAATAATACATACATGATTTTTCTTCTGAATGTCTCTTCTCCCTGCATCACTGTTCATTCACAATGAAAGGTTAGGAAGAAGCTTTAAA

>In-frame_ENST00000413765_ENST00000432641_TCGA-12-3652-01A_NRCAM_chr7_107830089_-_ACN9_chr7_96810324_length(amino acids)=669AA_start in transcript=471_stop in transcript=2480
MQLKIMPKKKRLSAGRVPLILFLCQMISALEVPLDQKSTEVMVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDID
KDPLVTMKPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFW
MDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVISAKSSRERPPTFLTPEGNASNKEELRGNVLS
LECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGT
LICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIAN
RPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQR
GSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAPTPTPAPVYDVPNP

--------------------------------------------------------------
>In-frame_ENST00000351718_ENST00000432641_TCGA-12-3652-01A_NRCAM_chr7_107830089_-_ACN9_chr7_96810324_length(transcript)=3167nt_BP=2415nt
AGCCAGAGGGGATAGCTTCGTCGAGAACGGAGGACACCGGCGGTCCAGGGTCCTGGGCAGTCGCGCCAGAGCTGAGCGGAGGGCGCGGCG
CGAGAACGAATCTTTGTGACATTCTCTCTCAGCATTCTTTATCCCCTGTTTGCTGAAGACTTCGACAAAAGCTGGTCTTAGCTGTTGGCA
TTCTCCTGAGAAAAGGATAGCTTCAGAAATCAGAAAAACATTTGGGAGGTGTCTAGCCCAGTGGACCTTCTGAAGAGCAATGCTAAGAAG
ACGTTTGGTTTAAAGAATTAAAAGGAAGAACAACTTAAGAGCTTCTTCAAAGTTTCCCGCATGAAAATTACTTAAACGTTGCACACAACG
TTTCACAAAATCTTTTGTGAAAGAAGAAAAGGAAATTCAGTGTGTGAGTCTCAGCAGGAGTTAAGCTAATGCAGCTTAAAATAATGCCGA
AAAAGAAGCGCTTATCTGCGGGCAGAGTGCCCCTGATTCTCTTCCTGTGCCAGATGATTAGTGCACTGGAAGTACCTCTTGATCTGGTAC
AGCCTCCAACCATCACCCAACAGTCTCCAAAAGATTACATTATTGACCCTCGGGAGAATATTGTAATCCAGTGTGAAGCCAAAGGGAAAC
CGCCCCCAAGCTTTTCCTGGACCCGTAATGGGACTCATTTTGACATCGATAAAGACCCTCTGGTCACCATGAAGCCTGGCACAGGAACGC
TCATAATTAACATCATGAGCGAAGGGAAAGCTGAGACCTATGAAGGAGTCTATCAGTGTACAGCAAGGAACGAACGCGGAGCTGCAGTTT
CTAATAACATTGTTGTCCGCCCATCCAGATCACCATTGTGGACCAAAGAAAAACTTGAACCAATCACACTTCAAAGTGGTCAGTCTTTAG
TACTTCCCTGCAGACCCCCAATTGGATTACCACCACCTATAATATTTTGGATGGATAATTCCTTTCAAAGACTTCCACAAAGTGAGAGAG
TTTCTCAAGGTTTGAATGGGGACCTTTATTTTTCCAATGTCCTCCCAGAGGACACCCGCGAAGACTATATCTGTTATGCTAGATTTAATC
ATACTCAAACCATACAGCAGAAGCAACCTATTTCTGTGAAGGTGATTTCAGTGGATGAATTGAATGACACTATAGCTGCTAATTTGAGTG
ACACTGAGTTTTATGGTGCTAAATCAAGTAGAGAGAGGCCACCAACATTTTTAACTCCAGAAGGCAATGCAAGTAACAAAGAGGAATTAA
GAGGAAATGTGCTTTCACTGGAGTGCATTGCAGAAGGACTGCCTACCCCAATTATTTACTGGGCAAAGGAAGATGGAATGCTACCCAAAA
ACAGGACAGTTTATAAGAACTTTGAGAAAACCTTGCAGATCATTCATGTTTCAGAAGCAGACTCTGGAAATTACCAATGTATAGCAAAAA
ACGCATTAGGAGCCATCCACCATACCATTTCTGTTAGAGTTAAAGCGGCTCCATACTGGATCACAGCCCCTCAAAATCTTGTGCTGTCCC
CAGGAGAGGATGGGACCTTGATCTGCAGAGCTAATGGCAACCCCAAACCCAGAATTAGCTGGTTAACAAATGGAGTCCCAATAGAAATTG
CCCCTGATGACCCCAGCAGAAAAATAGATGGCGATACCATTATTTTTTCAAATGTTCAAGAAAGATCAAGTGCAGTCTATCAGTGCAATG
CCTCTAATGAATATGGATATTTACTGGCAAACGCATTTGTAAATGTGCTGGCTGAGCCACCACGAATCCTCACACCTGCAAACACACTCT
ACCAGGTCATTGCAAACAGGCCTGCTTTACTAGACTGTGCCTTCTTTGGGTCTCCTCTCCCAACCATCGAGTGGTTTAAAGGAGCTAAAG
GAAGTGCTCTTCATGAAGATATTTATGTTTTACATGAAAATGGAACTTTGGAAATTCCTGTGGCCCAAAAGGACAGTACAGGAACTTATA
CGTGTGTTGCAAGGAATAAATTAGGGATGGCGAAGAATGAAGTTCACTTAGAAATCAAAGATCCTACATGGATCGTTAAACAGCCCGAAT
ATGCAGTTGTGCAAAGAGGGAGCATGGTGTCCTTTGAATGCAAAGTGAAACATGATCACACCTTATCCCTCACTGTCCTGTGGCTGAAGG
ACAACAGGGAACTGCCCAGTGATGAAAGGTTCACTGTTGACAAGGATCATCTAGTGGTAGCTGATGTCAGTGACGATGACAGCGGGACCT
ACACGTGTGTGGCCAACACCACTCTGGACAGCGTCTCCGCCAGCGCTGTGCTTAGCGTTGTTGATGTCCCAAATCCTCCCTTTGACTTAG
AACTGACAGATCAACTTGACAAAAGTGTTCAGCTGTCATGGACCCCAGGCGATGACAACAATAGCCCCATTACAAGTGTATGCAACAGCG
TTATTGCAACAGGCTAACGAAAACAGACAAAATTCAACTGGAAAAGCATGTTTTGGCACCTTCCTCCCAGAAGAAAAACTTAATGACTTT
CGTGATGAACAAATTGGACAGTTGCAGGAGCTGATGCAAGAAGCCACAAAACCCAATAGGCAATTTAGTATTTCTGAGTCTATGAAACCA
AAATTTTAGTCTATACAACAAAGCTTAATAAGACATGCAAAAATTTAGAACCCCTACTTTAACTGTCATTGGTTTTTGAAATATATTTAA
GCTTTGAAAACACCTGTTATTAATGAAATACTCTTTTATTTTGGATATTATGATTGCAGTATATGGATCAAGATCACTAGTGACAATTGA
AAAAAACTATTGGAATAATAGCACTTGTATGAAATTCAGTTTTGGAACTAAACAGCAAATTTCTAGAATTTTGCTGAAAATGTTTTAAAA
TGCTATTCTCATCCAGCCATATTAGTCTTCTGGCTTTTCTTTAGCTTCATCAAATAAGCATGTTGTGATAATGATAGATGTACAATTCCA
ACAAGGTTATTATTTTTTAAATACATTGTCATTCTGAACATTTTATCACTTCTAGTTTAATAATACATACATGATTTTTCTTCTGAATGT
CTCTTCTCCCTGCATCACTGTTCATTCACAATGAAAGGTTAGGAAGAAGCTTTAAAATTCACTATTTTACTATCAATCATTTGTATAATA

>In-frame_ENST00000351718_ENST00000432641_TCGA-12-3652-01A_NRCAM_chr7_107830089_-_ACN9_chr7_96810324_length(amino acids)=672AA_start in transcript=428_stop in transcript=2446
MQLKIMPKKKRLSAGRVPLILFLCQMISALEVPLDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVT
MKPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQ
RLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGN
ASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITA
PQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRI
LTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPT
WIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVDV

--------------------------------------------------------------
>In-frame_ENST00000379024_ENST00000432641_TCGA-12-3652-01A_NRCAM_chr7_107830089_-_ACN9_chr7_96810324_length(transcript)=3140nt_BP=2388nt
CGTCGAGAACGGAGGACACCGGCGGTCCAGGGTCCTGGGCAGTCGCGCCAGAGCTGAGCGGAGGGCGCGGCGCGAGAACGAATCTTTGTG
ACATTCTCTCTCAGCATTCTTTATCCCCTGTTTGCTGAAGACTTCGACAAAAGCTGGTCTTAGCTGTTGGCATTCTCCTGAGAAAAGGAT
AGCTTCAGAAATCAGAAAAACATTTGGGAGGTGTCTAGCCCAGTGGACCTTCTGAAGAGCAATGCTAAGAAGACGTTTGGTTTAAAGAAT
TAAAAGGAAGAACAACTTAAGAGCTTCTTCAAAGTTTCCCGCATGAAAATTACTTAAACGTTGCACACAACGTTTCACAAAATCTTTTGT
GAAAGAAGAAAAGGAAATTCAGTGTGTGAGTCTCAGCAGGAGTTAAGCTAATGCAGCTTAAAATAATGCCGAAAAAGAAGCGCTTATCTG
CGGGCAGAGTGCCCCTGATTCTCTTCCTGTGCCAGATGATTAGTGCACTGGAAGTACCTCTTGATCCAAAACTTCTTGAAGACTTGGTAC
AGCCTCCAACCATCACCCAACAGTCTCCAAAAGATTACATTATTGACCCTCGGGAGAATATTGTAATCCAGTGTGAAGCCAAAGGGAAAC
CGCCCCCAAGCTTTTCCTGGACCCGTAATGGGACTCATTTTGACATCGATAAAGACCCTCTGGTCACCATGAAGCCTGGCACAGGAACGC
TCATAATTAACATCATGAGCGAAGGGAAAGCTGAGACCTATGAAGGAGTCTATCAGTGTACAGCAAGGAACGAACGCGGAGCTGCAGTTT
CTAATAACATTGTTGTCCGCCCATCCAGATCACCATTGTGGACCAAAGAAAAACTTGAACCAATCACACTTCAAAGTGGTCAGTCTTTAG
TACTTCCCTGCAGACCCCCAATTGGATTACCACCACCTATAATATTTTGGATGGATAATTCCTTTCAAAGACTTCCACAAAGTGAGAGAG
TTTCTCAAGGTTTGAATGGGGACCTTTATTTTTCCAATGTCCTCCCAGAGGACACCCGCGAAGACTATATCTGTTATGCTAGATTTAATC
ATACTCAAACCATACAGCAGAAGCAACCTATTTCTGTGAAGGTGATTTCAGCTAAATCAAGTAGAGAGAGGCCACCAACATTTTTAACTC
CAGAAGGCAATGCAAGTAACAAAGAGGAATTAAGAGGAAATGTGCTTTCACTGGAGTGCATTGCAGAAGGACTGCCTACCCCAATTATTT
ACTGGGCAAAGGAAGATGGAATGCTACCCAAAAACAGGACAGTTTATAAGAACTTTGAGAAAACCTTGCAGATCATTCATGTTTCAGAAG
CAGACTCTGGAAATTACCAATGTATAGCAAAAAACGCATTAGGAGCCATCCACCATACCATTTCTGTTAGAGTTAAAGCGGCTCCATACT
GGATCACAGCCCCTCAAAATCTTGTGCTGTCCCCAGGAGAGGATGGGACCTTGATCTGCAGAGCTAATGGCAACCCCAAACCCAGAATTA
GCTGGTTAACAAATGGAGTCCCAATAGAAATTGCCCCTGATGACCCCAGCAGAAAAATAGATGGCGATACCATTATTTTTTCAAATGTTC
AAGAAAGATCAAGTGCAGTCTATCAGTGCAATGCCTCTAATGAATATGGATATTTACTGGCAAACGCATTTGTAAATGTGCTGGCTGAGC
CACCACGAATCCTCACACCTGCAAACACACTCTACCAGGTCATTGCAAACAGGCCTGCTTTACTAGACTGTGCCTTCTTTGGGTCTCCTC
TCCCAACCATCGAGTGGTTTAAAGGAGCTAAAGGAAGTGCTCTTCATGAAGATATTTATGTTTTACATGAAAATGGAACTTTGGAAATTC
CTGTGGCCCAAAAGGACAGTACAGGAACTTATACGTGTGTTGCAAGGAATAAATTAGGGATGGCGAAGAATGAAGTTCACTTAGAAATCA
AAGATCCTACATGGATCGTTAAACAGCCCGAATATGCAGTTGTGCAAAGAGGGAGCATGGTGTCCTTTGAATGCAAAGTGAAACATGATC
ACACCTTATCCCTCACTGTCCTGTGGCTGAAGGACAACAGGGAACTGCCCAGTGATGAAAGGTTCACTGTTGACAAGGATCATCTAGTGG
TAGCTGATGTCAGTGACGATGACAGCGGGACCTACACGTGTGTGGCCAACACCACTCTGGACAGCGTCTCCGCCAGCGCTGTGCTTAGCG
TTGTTGCTCCTACTCCAACTCCAGCTCCCGTTTACGATGTCCCAAATCCTCCCTTTGACTTAGAACTGACAGATCAACTTGACAAAAGTG
TTCAGCTGTCATGGACCCCAGGCGATGACAACAATAGCCCCATTACAAGTGTATGCAACAGCGTTATTGCAACAGGCTAACGAAAACAGA
CAAAATTCAACTGGAAAAGCATGTTTTGGCACCTTCCTCCCAGAAGAAAAACTTAATGACTTTCGTGATGAACAAATTGGACAGTTGCAG
GAGCTGATGCAAGAAGCCACAAAACCCAATAGGCAATTTAGTATTTCTGAGTCTATGAAACCAAAATTTTAGTCTATACAACAAAGCTTA
ATAAGACATGCAAAAATTTAGAACCCCTACTTTAACTGTCATTGGTTTTTGAAATATATTTAAGCTTTGAAAACACCTGTTATTAATGAA
ATACTCTTTTATTTTGGATATTATGATTGCAGTATATGGATCAAGATCACTAGTGACAATTGAAAAAAACTATTGGAATAATAGCACTTG
TATGAAATTCAGTTTTGGAACTAAACAGCAAATTTCTAGAATTTTGCTGAAAATGTTTTAAAATGCTATTCTCATCCAGCCATATTAGTC
TTCTGGCTTTTCTTTAGCTTCATCAAATAAGCATGTTGTGATAATGATAGATGTACAATTCCAACAAGGTTATTATTTTTTAAATACATT
GTCATTCTGAACATTTTATCACTTCTAGTTTAATAATACATACATGATTTTTCTTCTGAATGTCTCTTCTCCCTGCATCACTGTTCATTC

>In-frame_ENST00000379024_ENST00000432641_TCGA-12-3652-01A_NRCAM_chr7_107830089_-_ACN9_chr7_96810324_length(amino acids)=669AA_start in transcript=410_stop in transcript=2419
MQLKIMPKKKRLSAGRVPLILFLCQMISALEVPLDPKLLEDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDID
KDPLVTMKPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFW
MDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVISAKSSRERPPTFLTPEGNASNKEELRGNVLS
LECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGT
LICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIAN
RPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQR
GSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAPTPTPAPVYDVPNP

--------------------------------------------------------------
>In-frame_ENST00000379022_ENST00000432641_TCGA-12-3652-01A_NRCAM_chr7_107830089_-_ACN9_chr7_96810324_length(transcript)=3258nt_BP=2506nt
CGCGCGGGCGCGGGGGACGGCGCAGGGGCCGCCTGGCTGGAGCAGCCAGAGGGGATAGCTTCGTCGAGAACGGAGGACACCGGCGGTCCA
GGGTCCTGGGCAGTCGCGCCAGAGCTGAGCGGAGGGCGCGGCGCGAGAACGAATCTTTGTGACATTCTCTCTCAGCATTCTTTATCCCCT
GTTTGCTGAAGACTTCGACAAAAGCTGGTCTTAGCTGTTGGCATTCTCCTGAGAAAAGGATAGCTTCAGAAATCAGAAAAACATTTGGGA
GGTGTCTAGCCCAGTGGACCTTCTGAAGAGCAATGCTAAGAAGACGTTTGGTTTAAAGAATTAAAAGGAAGAACAACTTAAGAGCTTCTT
CAAAGTTTCCCGCATGAAAATTACTTAAACGTTGCACACAACGTTTCACAAAATCTTTTGTGAAAGAAGAAAAGGAAATTCAGTGTGTGA
GTCTCAGCAGGAGTTAAGCTAATGCAGCTTAAAATAATGCCGAAAAAGAAGCGCTTATCTGCGGGCAGAGTGCCCCTGATTCTCTTCCTG
TGCCAGATGATTAGTGCACTGGAAGTACCTCTTGATCAAAAATCTACTGAAGTAATGGTACAGCCTCCAACCATCACCCAACAGTCTCCA
AAAGATTACATTATTGACCCTCGGGAGAATATTGTAATCCAGTGTGAAGCCAAAGGGAAACCGCCCCCAAGCTTTTCCTGGACCCGTAAT
GGGACTCATTTTGACATCGATAAAGACCCTCTGGTCACCATGAAGCCTGGCACAGGAACGCTCATAATTAACATCATGAGCGAAGGGAAA
GCTGAGACCTATGAAGGAGTCTATCAGTGTACAGCAAGGAACGAACGCGGAGCTGCAGTTTCTAATAACATTGTTGTCCGCCCATCCAGA
TCACCATTGTGGACCAAAGAAAAACTTGAACCAATCACACTTCAAAGTGGTCAGTCTTTAGTACTTCCCTGCAGACCCCCAATTGGATTA
CCACCACCTATAATATTTTGGATGGATAATTCCTTTCAAAGACTTCCACAAAGTGAGAGAGTTTCTCAAGGTTTGAATGGGGACCTTTAT
TTTTCCAATGTCCTCCCAGAGGACACCCGCGAAGACTATATCTGTTATGCTAGATTTAATCATACTCAAACCATACAGCAGAAGCAACCT
ATTTCTGTGAAGGTGATTTCAGTGGATGAATTGAATGACACTATAGCTGCTAATTTGAGTGACACTGAGTTTTATGGTGCTAAATCAAGT
AGAGAGAGGCCACCAACATTTTTAACTCCAGAAGGCAATGCAAGTAACAAAGAGGAATTAAGAGGAAATGTGCTTTCACTGGAGTGCATT
GCAGAAGGACTGCCTACCCCAATTATTTACTGGGCAAAGGAAGATGGAATGCTACCCAAAAACAGGACAGTTTATAAGAACTTTGAGAAA
ACCTTGCAGATCATTCATGTTTCAGAAGCAGACTCTGGAAATTACCAATGTATAGCAAAAAACGCATTAGGAGCCATCCACCATACCATT
TCTGTTAGAGTTAAAGCGGCTCCATACTGGATCACAGCCCCTCAAAATCTTGTGCTGTCCCCAGGAGAGGATGGGACCTTGATCTGCAGA
GCTAATGGCAACCCCAAACCCAGAATTAGCTGGTTAACAAATGGAGTCCCAATAGAAATTGCCCCTGATGACCCCAGCAGAAAAATAGAT
GGCGATACCATTATTTTTTCAAATGTTCAAGAAAGATCAAGTGCAGTCTATCAGTGCAATGCCTCTAATGAATATGGATATTTACTGGCA
AACGCATTTGTAAATGTGCTGGCTGAGCCACCACGAATCCTCACACCTGCAAACACACTCTACCAGGTCATTGCAAACAGGCCTGCTTTA
CTAGACTGTGCCTTCTTTGGGTCTCCTCTCCCAACCATCGAGTGGTTTAAAGGAGCTAAAGGAAGTGCTCTTCATGAAGATATTTATGTT
TTACATGAAAATGGAACTTTGGAAATTCCTGTGGCCCAAAAGGACAGTACAGGAACTTATACGTGTGTTGCAAGGAATAAATTAGGGATG
GCGAAGAATGAAGTTCACTTAGAAATCAAAGATCCTACATGGATCGTTAAACAGCCCGAATATGCAGTTGTGCAAAGAGGGAGCATGGTG
TCCTTTGAATGCAAAGTGAAACATGATCACACCTTATCCCTCACTGTCCTGTGGCTGAAGGACAACAGGGAACTGCCCAGTGATGAAAGG
TTCACTGTTGACAAGGATCATCTAGTGGTAGCTGATGTCAGTGACGATGACAGCGGGACCTACACGTGTGTGGCCAACACCACTCTGGAC
AGCGTCTCCGCCAGCGCTGTGCTTAGCGTTGTTGCTCCTACTCCAACTCCAGCTCCCGTTTACGATGTCCCAAATCCTCCCTTTGACTTA
GAACTGACAGATCAACTTGACAAAAGTGTTCAGCTGTCATGGACCCCAGGCGATGACAACAATAGCCCCATTACAAGTGTATGCAACAGC
GTTATTGCAACAGGCTAACGAAAACAGACAAAATTCAACTGGAAAAGCATGTTTTGGCACCTTCCTCCCAGAAGAAAAACTTAATGACTT
TCGTGATGAACAAATTGGACAGTTGCAGGAGCTGATGCAAGAAGCCACAAAACCCAATAGGCAATTTAGTATTTCTGAGTCTATGAAACC
AAAATTTTAGTCTATACAACAAAGCTTAATAAGACATGCAAAAATTTAGAACCCCTACTTTAACTGTCATTGGTTTTTGAAATATATTTA
AGCTTTGAAAACACCTGTTATTAATGAAATACTCTTTTATTTTGGATATTATGATTGCAGTATATGGATCAAGATCACTAGTGACAATTG
AAAAAAACTATTGGAATAATAGCACTTGTATGAAATTCAGTTTTGGAACTAAACAGCAAATTTCTAGAATTTTGCTGAAAATGTTTTAAA
ATGCTATTCTCATCCAGCCATATTAGTCTTCTGGCTTTTCTTTAGCTTCATCAAATAAGCATGTTGTGATAATGATAGATGTACAATTCC
AACAAGGTTATTATTTTTTAAATACATTGTCATTCTGAACATTTTATCACTTCTAGTTTAATAATACATACATGATTTTTCTTCTGAATG
TCTCTTCTCCCTGCATCACTGTTCATTCACAATGAAAGGTTAGGAAGAAGCTTTAAAATTCACTATTTTACTATCAATCATTTGTATAAT

>In-frame_ENST00000379022_ENST00000432641_TCGA-12-3652-01A_NRCAM_chr7_107830089_-_ACN9_chr7_96810324_length(amino acids)=688AA_start in transcript=471_stop in transcript=2537
MQLKIMPKKKRLSAGRVPLILFLCQMISALEVPLDQKSTEVMVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDID
KDPLVTMKPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFW
MDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTF
LTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAA
PYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVL
AEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHL
EIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVADVSDDDSGTYTCVANTTLDSVSASAV

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>In-frame_ENST00000425651_ENST00000432641_TCGA-12-3652-01A_NRCAM_chr7_107830089_-_ACN9_chr7_96810324_length(transcript)=2787nt_BP=2035nt
ATGCAGCTTAAAATAATGCCGAAAAAGAAGCGCTTATCTGCGGGCAGAGTGCCCCTGATTCTCTTCCTGTGCCAGATGATTAGTGCACTG
GAAGTACCTCTTGATCCAAAACTTCTTGAAGACTTGGTACAGCCTCCAACCATCACCCAACAGTCTCCAAAAGATTACATTATTGACCCT
CGGGAGAATATTGTAATCCAGTGTGAAGCCAAAGGGAAACCGCCCCCAAGCTTTTCCTGGACCCGTAATGGGACTCATTTTGACATCGAT
AAAGACCCTCTGGTCACCATGAAGCCTGGCACAGGAACGCTCATAATTAACATCATGAGCGAAGGGAAAGCTGAGACCTATGAAGGAGTC
TATCAGTGTACAGCAAGGAACGAACGCGGAGCTGCAGTTTCTAATAACATTGTTGTCCGCCCATCCAGATCACCATTGTGGACCAAAGAA
AAACTTGAACCAATCACACTTCAAAGTGGTCAGTCTTTAGTACTTCCCTGCAGACCCCCAATTGGATTACCACCACCTATAATATTTTGG
ATGGATAATTCCTTTCAAAGACTTCCACAAAGTGAGAGAGTTTCTCAAGGTTTGAATGGGGACCTTTATTTTTCCAATGTCCTCCCAGAG
GACACCCGCGAAGACTATATCTGTTATGCTAGATTTAATCATACTCAAACCATACAGCAGAAGCAACCTATTTCTGTGAAGGTGATTTCA
GTGGATGAATTGAATGACACTATAGCTGCTAATTTGAGTGACACTGAGTTTTATGGTGCTAAATCAAGTAGAGAGAGGCCACCAACATTT
TTAACTCCAGAAGGCAATGCAAGTAACAAAGAGGAATTAAGAGGAAATGTGCTTTCACTGGAGTGCATTGCAGAAGGACTGCCTACCCCA
ATTATTTACTGGGCAAAGGAAGATGGAATGCTACCCAAAAACAGGACAGTTTATAAGAACTTTGAGAAAACCTTGCAGATCATTCATGTT
TCAGAAGCAGACTCTGGAAATTACCAATGTATAGCAAAAAACGCATTAGGAGCCATCCACCATACCATTTCTGTTAGAGTTAAAGCGGCT
CCATACTGGATCACAGCCCCTCAAAATCTTGTGCTGTCCCCAGGAGAGGATGGGACCTTGATCTGCAGAGCTAATGGCAACCCCAAACCC
AGAATTAGCTGGTTAACAAATGGAGTCCCAATAGAAATTGCCCCTGATGACCCCAGCAGAAAAATAGATGGCGATACCATTATTTTTTCA
AATGTTCAAGAAAGATCAAGTGCAGTCTATCAGTGCAATGCCTCTAATGAATATGGATATTTACTGGCAAACGCATTTGTAAATGTGCTG
GCTGAGCCACCACGAATCCTCACACCTGCAAACACACTCTACCAGGTCATTGCAAACAGGCCTGCTTTACTAGACTGTGCCTTCTTTGGG
TCTCCTCTCCCAACCATCGAGTGGTTTAAAGGAGCTAAAGGAAGTGCTCTTCATGAAGATATTTATGTTTTACATGAAAATGGAACTTTG
GAAATTCCTGTGGCCCAAAAGGACAGTACAGGAACTTATACGTGTGTTGCAAGGAATAAATTAGGGATGGCGAAGAATGAAGTTCACTTA
GAAATCAAAGATCCTACATGGATCGTTAAACAGCCCGAATATGCAGTTGTGCAAAGAGGGAGCATGGTGTCCTTTGAATGCAAAGTGAAA
CATGATCACACCTTATCCCTCACTGTCCTGTGGCTGAAGGACAACAGGGAACTGCCCAGTGATGAAAGGTTCACTGTTGACAAGGATCAT
CTAGTGGTAGCTGATGTCAGTGACGATGACAGCGGGACCTACACGTGTGTGGCCAACACCACTCTGGACAGCGTCTCCGCCAGCGCTGTG
CTTAGCGTTGTTGCTCCTACTCCAACTCCAGCTCCCGTTTACGATGTCCCAAATCCTCCCTTTGACTTAGAACTGACAGATCAACTTGAC
AAAAGTGTTCAGCTGTCATGGACCCCAGGCGATGACAACAATAGCCCCATTACAAGTGTATGCAACAGCGTTATTGCAACAGGCTAACGA
AAACAGACAAAATTCAACTGGAAAAGCATGTTTTGGCACCTTCCTCCCAGAAGAAAAACTTAATGACTTTCGTGATGAACAAATTGGACA
GTTGCAGGAGCTGATGCAAGAAGCCACAAAACCCAATAGGCAATTTAGTATTTCTGAGTCTATGAAACCAAAATTTTAGTCTATACAACA
AAGCTTAATAAGACATGCAAAAATTTAGAACCCCTACTTTAACTGTCATTGGTTTTTGAAATATATTTAAGCTTTGAAAACACCTGTTAT
TAATGAAATACTCTTTTATTTTGGATATTATGATTGCAGTATATGGATCAAGATCACTAGTGACAATTGAAAAAAACTATTGGAATAATA
GCACTTGTATGAAATTCAGTTTTGGAACTAAACAGCAAATTTCTAGAATTTTGCTGAAAATGTTTTAAAATGCTATTCTCATCCAGCCAT
ATTAGTCTTCTGGCTTTTCTTTAGCTTCATCAAATAAGCATGTTGTGATAATGATAGATGTACAATTCCAACAAGGTTATTATTTTTTAA
ATACATTGTCATTCTGAACATTTTATCACTTCTAGTTTAATAATACATACATGATTTTTCTTCTGAATGTCTCTTCTCCCTGCATCACTG

>In-frame_ENST00000425651_ENST00000432641_TCGA-12-3652-01A_NRCAM_chr7_107830089_-_ACN9_chr7_96810324_length(amino acids)=688AA_start in transcript=0_stop in transcript=2066
MQLKIMPKKKRLSAGRVPLILFLCQMISALEVPLDPKLLEDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDID
KDPLVTMKPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFW
MDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTF
LTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAA
PYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVL
AEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHL
EIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVADVSDDDSGTYTCVANTTLDSVSASAV

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Fusion Gene PPI Analysis for NRCAM-ACN9


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for NRCAM-ACN9


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for NRCAM-ACN9


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneNRCAMC0004352Autistic Disorder2CTD_human
HgeneNRCAMC0009402Colorectal Carcinoma2CTD_human
HgeneNRCAMC0009404Colorectal Neoplasms2CTD_human
HgeneNRCAMC0006142Malignant neoplasm of breast1CTD_human;UNIPROT
HgeneNRCAMC0013146Drug abuse1CTD_human
HgeneNRCAMC0013170Drug habituation1CTD_human
HgeneNRCAMC0013222Drug Use Disorders1CTD_human
HgeneNRCAMC0029231Organic Mental Disorders, Substance-Induced1CTD_human
HgeneNRCAMC0038580Substance Dependence1CTD_human
HgeneNRCAMC0038586Substance Use Disorders1CTD_human
HgeneNRCAMC0236969Substance-Related Disorders1CTD_human
HgeneNRCAMC0678222Breast Carcinoma1CTD_human
HgeneNRCAMC0740858Substance abuse problem1CTD_human
HgeneNRCAMC1257931Mammary Neoplasms, Human1CTD_human
HgeneNRCAMC1458155Mammary Neoplasms1CTD_human
HgeneNRCAMC1510472Drug Dependence1CTD_human
HgeneNRCAMC4316881Prescription Drug Abuse1CTD_human
HgeneNRCAMC4704874Mammary Carcinoma, Human1CTD_human