FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:NRXN3-CFB (FusionGDB2 ID:60013)

Fusion Gene Summary for NRXN3-CFB

check button Fusion gene summary
Fusion gene informationFusion gene name: NRXN3-CFB
Fusion gene ID: 60013
HgeneTgene
Gene symbol

NRXN3

CFB

Gene ID

9369

629

Gene nameneurexin 3complement factor B
SynonymsC14orf60AHUS4|ARMD14|BF|BFD|CFAB|CFBD|FB|FBI12|GBG|H2-Bf|PBF2
Cytomap

14q24.3-q31.1

6p21.33

Type of geneprotein-codingprotein-coding
Descriptionneurexin 3neurexin IIIneurexin-3-alphacomplement factor BB-factor, properdinC3 proacceleratorC3 proactivatorC3/C5 convertaseglycine-rich beta-glycoproteinproperdin factor B
Modification date2020031320200327
UniProtAcc.

P00751

Ensembl transtripts involved in fusion geneENST00000554719, ENST00000335750, 
ENST00000557594, ENST00000281127, 
ENST00000428277, ENST00000556003, 
ENST00000556679, ENST00000456570, 
ENST00000477310, ENST00000425368, 
ENST00000497841, ENST00000417261, 
ENST00000427888, ENST00000459734, 
ENST00000455591, ENST00000433503, 
ENST00000474621, ENST00000424727, 
ENST00000436692, ENST00000473139, 
ENST00000399981, ENST00000419920, 
ENST00000465211, ENST00000375455, 
ENST00000489605, ENST00000426239, 
ENST00000419411, ENST00000460958, 
Fusion gene scores* DoF score14 X 14 X 5=98017 X 11 X 9=1683
# samples 1420
** MAII scorelog2(14/980*10)=-2.8073549220576
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(20/1683*10)=-3.07296327155522
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: NRXN3 [Title/Abstract] AND CFB [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointNRXN3(79780492)-CFB(31901387), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across NRXN3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across CFB (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4ESCATCGA-R6-A8W8NRXN3chr14

79780492

+CFBchr6

31901387

+
ChimerDB4ESCATCGA-R6-A8W8NRXN3chr14

79780492

+CFBchr6

31901387

+


Top

Fusion Gene ORF analysis for NRXN3-CFB

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
intron-3CDSENST00000554719ENST00000556679NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-3CDSENST00000554719ENST00000456570NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000554719ENST00000477310NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000554719ENST00000425368NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000554719ENST00000497841NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000554719ENST00000417261NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000554719ENST00000427888NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000554719ENST00000459734NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000554719ENST00000455591NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000554719ENST00000433503NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000554719ENST00000474621NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000554719ENST00000424727NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000554719ENST00000436692NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000554719ENST00000473139NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000554719ENST00000399981NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000554719ENST00000419920NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000554719ENST00000465211NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000554719ENST00000375455NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000554719ENST00000489605NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000554719ENST00000426239NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000554719ENST00000419411NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000554719ENST00000460958NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-3CDSENST00000335750ENST00000556679NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-3CDSENST00000335750ENST00000456570NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000335750ENST00000477310NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000335750ENST00000425368NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000335750ENST00000497841NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000335750ENST00000417261NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000335750ENST00000427888NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000335750ENST00000459734NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000335750ENST00000455591NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000335750ENST00000433503NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000335750ENST00000474621NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000335750ENST00000424727NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000335750ENST00000436692NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000335750ENST00000473139NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000335750ENST00000399981NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000335750ENST00000419920NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000335750ENST00000465211NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000335750ENST00000375455NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000335750ENST00000489605NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000335750ENST00000426239NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000335750ENST00000419411NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000335750ENST00000460958NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-3CDSENST00000557594ENST00000556679NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-3CDSENST00000557594ENST00000456570NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000557594ENST00000477310NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000557594ENST00000425368NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000557594ENST00000497841NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000557594ENST00000417261NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000557594ENST00000427888NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000557594ENST00000459734NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000557594ENST00000455591NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000557594ENST00000433503NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000557594ENST00000474621NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000557594ENST00000424727NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000557594ENST00000436692NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000557594ENST00000473139NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000557594ENST00000399981NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000557594ENST00000419920NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000557594ENST00000465211NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000557594ENST00000375455NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000557594ENST00000489605NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000557594ENST00000426239NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000557594ENST00000419411NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000557594ENST00000460958NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-3CDSENST00000281127ENST00000556679NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-3CDSENST00000281127ENST00000456570NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000281127ENST00000477310NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000281127ENST00000425368NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000281127ENST00000497841NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000281127ENST00000417261NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000281127ENST00000427888NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000281127ENST00000459734NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000281127ENST00000455591NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000281127ENST00000433503NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000281127ENST00000474621NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000281127ENST00000424727NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000281127ENST00000436692NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000281127ENST00000473139NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000281127ENST00000399981NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000281127ENST00000419920NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000281127ENST00000465211NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000281127ENST00000375455NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000281127ENST00000489605NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000281127ENST00000426239NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000281127ENST00000419411NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000281127ENST00000460958NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-3CDSENST00000428277ENST00000556679NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-3CDSENST00000428277ENST00000456570NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000428277ENST00000477310NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000428277ENST00000425368NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000428277ENST00000497841NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000428277ENST00000417261NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000428277ENST00000427888NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000428277ENST00000459734NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000428277ENST00000455591NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000428277ENST00000433503NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000428277ENST00000474621NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000428277ENST00000424727NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000428277ENST00000436692NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000428277ENST00000473139NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000428277ENST00000399981NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000428277ENST00000419920NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000428277ENST00000465211NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000428277ENST00000375455NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000428277ENST00000489605NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000428277ENST00000426239NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000428277ENST00000419411NRXN3chr14

79780492

+CFBchr6

31901387

+
intron-intronENST00000428277ENST00000460958NRXN3chr14

79780492

+CFBchr6

31901387

+
3UTR-3CDSENST00000556003ENST00000556679NRXN3chr14

79780492

+CFBchr6

31901387

+
3UTR-3CDSENST00000556003ENST00000456570NRXN3chr14

79780492

+CFBchr6

31901387

+
3UTR-intronENST00000556003ENST00000477310NRXN3chr14

79780492

+CFBchr6

31901387

+
3UTR-intronENST00000556003ENST00000425368NRXN3chr14

79780492

+CFBchr6

31901387

+
3UTR-intronENST00000556003ENST00000497841NRXN3chr14

79780492

+CFBchr6

31901387

+
3UTR-intronENST00000556003ENST00000417261NRXN3chr14

79780492

+CFBchr6

31901387

+
3UTR-intronENST00000556003ENST00000427888NRXN3chr14

79780492

+CFBchr6

31901387

+
3UTR-intronENST00000556003ENST00000459734NRXN3chr14

79780492

+CFBchr6

31901387

+
3UTR-intronENST00000556003ENST00000455591NRXN3chr14

79780492

+CFBchr6

31901387

+
3UTR-intronENST00000556003ENST00000433503NRXN3chr14

79780492

+CFBchr6

31901387

+
3UTR-intronENST00000556003ENST00000474621NRXN3chr14

79780492

+CFBchr6

31901387

+
3UTR-intronENST00000556003ENST00000424727NRXN3chr14

79780492

+CFBchr6

31901387

+
3UTR-intronENST00000556003ENST00000436692NRXN3chr14

79780492

+CFBchr6

31901387

+
3UTR-intronENST00000556003ENST00000473139NRXN3chr14

79780492

+CFBchr6

31901387

+
3UTR-intronENST00000556003ENST00000399981NRXN3chr14

79780492

+CFBchr6

31901387

+
3UTR-intronENST00000556003ENST00000419920NRXN3chr14

79780492

+CFBchr6

31901387

+
3UTR-intronENST00000556003ENST00000465211NRXN3chr14

79780492

+CFBchr6

31901387

+
3UTR-intronENST00000556003ENST00000375455NRXN3chr14

79780492

+CFBchr6

31901387

+
3UTR-intronENST00000556003ENST00000489605NRXN3chr14

79780492

+CFBchr6

31901387

+
3UTR-intronENST00000556003ENST00000426239NRXN3chr14

79780492

+CFBchr6

31901387

+
3UTR-intronENST00000556003ENST00000419411NRXN3chr14

79780492

+CFBchr6

31901387

+
3UTR-intronENST00000556003ENST00000460958NRXN3chr14

79780492

+CFBchr6

31901387

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score

Top

Fusion Genomic Features for NRXN3-CFB


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
NRXN3chr1479780492+CFBchr631901386+0.0199767870.98002326
NRXN3chr1479780492+CFBchr631901386+0.0199767870.98002326

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

Top

Fusion Protein Features for NRXN3-CFB


check button Go to

FGviewer for the breakpoints of :-:

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.CFB

P00751

FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


Top

Fusion Gene Sequence for NRXN3-CFB


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

Top

Fusion Gene PPI Analysis for NRXN3-CFB


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for NRXN3-CFB


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
TgeneCFBP00751DB01593ZincSmall moleculeApproved|Investigational
TgeneCFBP00751DB01593ZincSmall moleculeApproved|Investigational
TgeneCFBP00751DB01593ZincSmall moleculeApproved|Investigational
TgeneCFBP00751DB14487Zinc acetateSmall moleculeApproved|Investigational
TgeneCFBP00751DB14487Zinc acetateSmall moleculeApproved|Investigational
TgeneCFBP00751DB14487Zinc acetateSmall moleculeApproved|Investigational

Top

Related Diseases for NRXN3-CFB


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneNRXN3C0001973Alcoholic Intoxication, Chronic1PSYGENET
HgeneNRXN3C0004352Autistic Disorder1GENOMICS_ENGLAND
HgeneNRXN3C0013146Drug abuse1CTD_human
HgeneNRXN3C0013170Drug habituation1CTD_human
HgeneNRXN3C0013222Drug Use Disorders1CTD_human
HgeneNRXN3C0029231Organic Mental Disorders, Substance-Induced1CTD_human
HgeneNRXN3C0036341Schizophrenia1PSYGENET
HgeneNRXN3C0038580Substance Dependence1CTD_human
HgeneNRXN3C0038586Substance Use Disorders1CTD_human
HgeneNRXN3C0236969Substance-Related Disorders1CTD_human
HgeneNRXN3C0740858Substance abuse problem1CTD_human
HgeneNRXN3C0853193Bipolar I disorder1PSYGENET
HgeneNRXN3C1510472Drug Dependence1CTD_human
HgeneNRXN3C1510586Autism Spectrum Disorders1GENOMICS_ENGLAND
HgeneNRXN3C4316881Prescription Drug Abuse1CTD_human
TgeneCFBC2752038HEMOLYTIC UREMIC SYNDROME, ATYPICAL, SUSCEPTIBILITY TO, 45GENOMICS_ENGLAND;UNIPROT
TgeneCFBC2931788Atypical Hemolytic Uremic Syndrome3CTD_human;GENOMICS_ENGLAND
TgeneCFBC0017662Glomerulonephritis, Membranoproliferative1GENOMICS_ENGLAND
TgeneCFBC0019061Hemolytic-Uremic Syndrome1GENOMICS_ENGLAND
TgeneCFBC0024141Lupus Erythematosus, Systemic1CTD_human
TgeneCFBC0026896Myasthenia Gravis1CTD_human
TgeneCFBC0242380Libman-Sacks Disease1CTD_human
TgeneCFBC0242383Age related macular degeneration1CTD_human;GENOMICS_ENGLAND
TgeneCFBC0272242Complement deficiency disease1GENOMICS_ENGLAND
TgeneCFBC0751339Myasthenia Gravis, Generalized1CTD_human
TgeneCFBC0751340Myasthenia Gravis, Ocular1CTD_human
TgeneCFBC3809950COMPLEMENT FACTOR B DEFICIENCY1CTD_human;GENOMICS_ENGLAND
TgeneCFBC4087273C3 glomerulopathy1GENOMICS_ENGLAND