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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:NUMA1-PITPNM1 (FusionGDB2 ID:60541)

Fusion Gene Summary for NUMA1-PITPNM1

check button Fusion gene summary
Fusion gene informationFusion gene name: NUMA1-PITPNM1
Fusion gene ID: 60541
HgeneTgene
Gene symbol

NUMA1

PITPNM1

Gene ID

4926

9600

Gene namenuclear mitotic apparatus protein 1phosphatidylinositol transfer protein membrane associated 1
SynonymsNMP-22|NUMADRES9|NIR2|PITPNM|RDGB|RDGB1|RDGBA|RDGBA1|Rd9
Cytomap

11q13.4

11q13.2

Type of geneprotein-codingprotein-coding
Descriptionnuclear mitotic apparatus protein 1SP-H antigencentrophilin stabilizes mitotic spindle in mitotic cellsnuclear matrix protein-22structural nuclear proteinmembrane-associated phosphatidylinositol transfer protein 1NIR-2PITPnm 1PYK2 N-terminal domain-interacting receptor 2drosophila retinal degeneration B homologretinal degeneration B alpha 1
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000351960, ENST00000358965, 
ENST00000393695, ENST00000543450, 
ENST00000534749, ENST00000436757, 
ENST00000356404, ENST00000526450, 
Fusion gene scores* DoF score36 X 22 X 17=134644 X 7 X 2=56
# samples 436
** MAII scorelog2(43/13464*10)=-4.96862661174049
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(6/56*10)=0.0995356735509144
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: NUMA1 [Title/Abstract] AND PITPNM1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointNUMA1(71718235)-PITPNM1(67265793), # samples:3
PITPNM1(67271574)-NUMA1(71747021), # samples:1
Anticipated loss of major functional domain due to fusion event.NUMA1-PITPNM1 seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF.
NUMA1-PITPNM1 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneNUMA1

GO:0000132

establishment of mitotic spindle orientation

21816348

HgeneNUMA1

GO:0030953

astral microtubule organization

12445386

HgeneNUMA1

GO:0060236

regulation of mitotic spindle organization

26195665

HgeneNUMA1

GO:1902365

positive regulation of protein localization to spindle pole body

16076287

TgenePITPNM1

GO:0015914

phospholipid transport

22822086


check buttonFusion gene breakpoints across NUMA1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across PITPNM1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-E2-A107-01ANUMA1chr11

71718235

-PITPNM1chr11

67265793

-
ChimerDB4BRCATCGA-E2-A107NUMA1chr11

71718234

-PITPNM1chr11

67265793

-
ChimerDB4BRCATCGA-E2-A107-01ANUMA1chr11

71718235

-PITPNM1chr11

67265793

-
ChimerDB4BRCATCGA-E2-A107-01ANUMA1chr11

71718235

-PITPNM1chr11

67265793

-


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Fusion Gene ORF analysis for NUMA1-PITPNM1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000351960ENST00000534749NUMA1chr11

71718235

-PITPNM1chr11

67265793

-
Frame-shiftENST00000351960ENST00000436757NUMA1chr11

71718235

-PITPNM1chr11

67265793

-
Frame-shiftENST00000351960ENST00000356404NUMA1chr11

71718235

-PITPNM1chr11

67265793

-
5CDS-intronENST00000351960ENST00000526450NUMA1chr11

71718235

-PITPNM1chr11

67265793

-
In-frameENST00000358965ENST00000534749NUMA1chr11

71718235

-PITPNM1chr11

67265793

-
In-frameENST00000358965ENST00000436757NUMA1chr11

71718235

-PITPNM1chr11

67265793

-
In-frameENST00000358965ENST00000356404NUMA1chr11

71718235

-PITPNM1chr11

67265793

-
5CDS-intronENST00000358965ENST00000526450NUMA1chr11

71718235

-PITPNM1chr11

67265793

-
Frame-shiftENST00000393695ENST00000534749NUMA1chr11

71718235

-PITPNM1chr11

67265793

-
Frame-shiftENST00000393695ENST00000436757NUMA1chr11

71718235

-PITPNM1chr11

67265793

-
Frame-shiftENST00000393695ENST00000356404NUMA1chr11

71718235

-PITPNM1chr11

67265793

-
5CDS-intronENST00000393695ENST00000526450NUMA1chr11

71718235

-PITPNM1chr11

67265793

-
intron-3CDSENST00000543450ENST00000534749NUMA1chr11

71718235

-PITPNM1chr11

67265793

-
intron-3CDSENST00000543450ENST00000436757NUMA1chr11

71718235

-PITPNM1chr11

67265793

-
intron-3CDSENST00000543450ENST00000356404NUMA1chr11

71718235

-PITPNM1chr11

67265793

-
intron-intronENST00000543450ENST00000526450NUMA1chr11

71718235

-PITPNM1chr11

67265793

-
Frame-shiftENST00000351960ENST00000534749NUMA1chr11

71718234

-PITPNM1chr11

67265793

-
Frame-shiftENST00000351960ENST00000436757NUMA1chr11

71718234

-PITPNM1chr11

67265793

-
Frame-shiftENST00000351960ENST00000356404NUMA1chr11

71718234

-PITPNM1chr11

67265793

-
5CDS-intronENST00000351960ENST00000526450NUMA1chr11

71718234

-PITPNM1chr11

67265793

-
In-frameENST00000358965ENST00000534749NUMA1chr11

71718234

-PITPNM1chr11

67265793

-
In-frameENST00000358965ENST00000436757NUMA1chr11

71718234

-PITPNM1chr11

67265793

-
In-frameENST00000358965ENST00000356404NUMA1chr11

71718234

-PITPNM1chr11

67265793

-
5CDS-intronENST00000358965ENST00000526450NUMA1chr11

71718234

-PITPNM1chr11

67265793

-
Frame-shiftENST00000393695ENST00000534749NUMA1chr11

71718234

-PITPNM1chr11

67265793

-
Frame-shiftENST00000393695ENST00000436757NUMA1chr11

71718234

-PITPNM1chr11

67265793

-
Frame-shiftENST00000393695ENST00000356404NUMA1chr11

71718234

-PITPNM1chr11

67265793

-
5CDS-intronENST00000393695ENST00000526450NUMA1chr11

71718234

-PITPNM1chr11

67265793

-
intron-3CDSENST00000543450ENST00000534749NUMA1chr11

71718234

-PITPNM1chr11

67265793

-
intron-3CDSENST00000543450ENST00000436757NUMA1chr11

71718234

-PITPNM1chr11

67265793

-
intron-3CDSENST00000543450ENST00000356404NUMA1chr11

71718234

-PITPNM1chr11

67265793

-
intron-intronENST00000543450ENST00000526450NUMA1chr11

71718234

-PITPNM1chr11

67265793

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000358965NUMA1chr1171718235-ENST00000534749PITPNM1chr1167265793-8195567924058461868
ENST00000358965NUMA1chr1171718235-ENST00000436757PITPNM1chr1167265793-8192567924058461868
ENST00000358965NUMA1chr1171718235-ENST00000356404PITPNM1chr1167265793-8194567924058461868
ENST00000358965NUMA1chr1171718234-ENST00000534749PITPNM1chr1167265793-8195567924058461868
ENST00000358965NUMA1chr1171718234-ENST00000436757PITPNM1chr1167265793-8192567924058461868
ENST00000358965NUMA1chr1171718234-ENST00000356404PITPNM1chr1167265793-8194567924058461868

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000358965ENST00000534749NUMA1chr1171718235-PITPNM1chr1167265793-0.0276037850.9723962
ENST00000358965ENST00000436757NUMA1chr1171718235-PITPNM1chr1167265793-0.0275163460.97248363
ENST00000358965ENST00000356404NUMA1chr1171718235-PITPNM1chr1167265793-0.0276096570.9723903
ENST00000358965ENST00000534749NUMA1chr1171718234-PITPNM1chr1167265793-0.0276037850.9723962
ENST00000358965ENST00000436757NUMA1chr1171718234-PITPNM1chr1167265793-0.0275163460.97248363
ENST00000358965ENST00000356404NUMA1chr1171718234-PITPNM1chr1167265793-0.0276096570.9723903

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Fusion Genomic Features for NUMA1-PITPNM1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for NUMA1-PITPNM1


check button Go to

FGviewer for the breakpoints of chr11:71718235-chr11:67265793

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNUMA1chr11:71718234chr11:67265793ENST00000358965-2127213_16991807.02102.0Coiled coilOntology_term=ECO:0000255
HgeneNUMA1chr11:71718234chr11:67265793ENST00000393695-2127213_16991821.02116.0Coiled coilOntology_term=ECO:0000255
HgeneNUMA1chr11:71718235chr11:67265793ENST00000358965-2127213_16991807.02102.0Coiled coilOntology_term=ECO:0000255
HgeneNUMA1chr11:71718235chr11:67265793ENST00000393695-2127213_16991821.02116.0Coiled coilOntology_term=ECO:0000255
HgeneNUMA1chr11:71718234chr11:67265793ENST00000358965-21271742_17481807.02102.0MotifTankyrase-binding domain
HgeneNUMA1chr11:71718234chr11:67265793ENST00000393695-21271742_17481821.02116.0MotifTankyrase-binding domain
HgeneNUMA1chr11:71718235chr11:67265793ENST00000358965-21271742_17481807.02102.0MotifTankyrase-binding domain
HgeneNUMA1chr11:71718235chr11:67265793ENST00000393695-21271742_17481821.02116.0MotifTankyrase-binding domain
HgeneNUMA1chr11:71718234chr11:67265793ENST00000358965-21271788_18101807.02102.0Region4.1-binding domain
HgeneNUMA1chr11:71718234chr11:67265793ENST00000358965-21271_2121807.02102.0RegionNote=Head (Globular)
HgeneNUMA1chr11:71718234chr11:67265793ENST00000393695-21271788_18101821.02116.0Region4.1-binding domain
HgeneNUMA1chr11:71718234chr11:67265793ENST00000393695-21271_2121821.02116.0RegionNote=Head (Globular)
HgeneNUMA1chr11:71718235chr11:67265793ENST00000358965-21271788_18101807.02102.0Region4.1-binding domain
HgeneNUMA1chr11:71718235chr11:67265793ENST00000358965-21271_2121807.02102.0RegionNote=Head (Globular)
HgeneNUMA1chr11:71718235chr11:67265793ENST00000393695-21271788_18101821.02116.0Region4.1-binding domain
HgeneNUMA1chr11:71718235chr11:67265793ENST00000393695-21271_2121821.02116.0RegionNote=Head (Globular)
TgenePITPNM1chr11:71718234chr11:67265793ENST00000356404924686_880494.66666666666671245.0DomainDDHD
TgenePITPNM1chr11:71718234chr11:67265793ENST00000436757924686_880494.66666666666671244.0DomainDDHD
TgenePITPNM1chr11:71718234chr11:67265793ENST00000534749823686_880494.66666666666671245.0DomainDDHD
TgenePITPNM1chr11:71718235chr11:67265793ENST00000356404924686_880494.66666666666671245.0DomainDDHD
TgenePITPNM1chr11:71718235chr11:67265793ENST00000436757924686_880494.66666666666671244.0DomainDDHD
TgenePITPNM1chr11:71718235chr11:67265793ENST00000534749823686_880494.66666666666671245.0DomainDDHD

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNUMA1chr11:71718234chr11:67265793ENST00000358965-21271984_19891807.02102.0MotifNuclear localization signal
HgeneNUMA1chr11:71718234chr11:67265793ENST00000393695-21271984_19891821.02116.0MotifNuclear localization signal
HgeneNUMA1chr11:71718235chr11:67265793ENST00000358965-21271984_19891807.02102.0MotifNuclear localization signal
HgeneNUMA1chr11:71718235chr11:67265793ENST00000393695-21271984_19891821.02116.0MotifNuclear localization signal
HgeneNUMA1chr11:71718234chr11:67265793ENST00000358965-21271699_18761807.02102.0RegionMembrane-binding domain 1
HgeneNUMA1chr11:71718234chr11:67265793ENST00000358965-21271700_21151807.02102.0RegionNote=Tail (Globular)
HgeneNUMA1chr11:71718234chr11:67265793ENST00000358965-21271882_19851807.02102.0RegionTubulin-binding domain
HgeneNUMA1chr11:71718234chr11:67265793ENST00000358965-21271892_19261807.02102.0RegionGPSM2-binding domain
HgeneNUMA1chr11:71718234chr11:67265793ENST00000358965-21271981_20601807.02102.0RegionMembrane-binding domain 2
HgeneNUMA1chr11:71718234chr11:67265793ENST00000393695-21271699_18761821.02116.0RegionMembrane-binding domain 1
HgeneNUMA1chr11:71718234chr11:67265793ENST00000393695-21271700_21151821.02116.0RegionNote=Tail (Globular)
HgeneNUMA1chr11:71718234chr11:67265793ENST00000393695-21271882_19851821.02116.0RegionTubulin-binding domain
HgeneNUMA1chr11:71718234chr11:67265793ENST00000393695-21271892_19261821.02116.0RegionGPSM2-binding domain
HgeneNUMA1chr11:71718234chr11:67265793ENST00000393695-21271981_20601821.02116.0RegionMembrane-binding domain 2
HgeneNUMA1chr11:71718235chr11:67265793ENST00000358965-21271699_18761807.02102.0RegionMembrane-binding domain 1
HgeneNUMA1chr11:71718235chr11:67265793ENST00000358965-21271700_21151807.02102.0RegionNote=Tail (Globular)
HgeneNUMA1chr11:71718235chr11:67265793ENST00000358965-21271882_19851807.02102.0RegionTubulin-binding domain
HgeneNUMA1chr11:71718235chr11:67265793ENST00000358965-21271892_19261807.02102.0RegionGPSM2-binding domain
HgeneNUMA1chr11:71718235chr11:67265793ENST00000358965-21271981_20601807.02102.0RegionMembrane-binding domain 2
HgeneNUMA1chr11:71718235chr11:67265793ENST00000393695-21271699_18761821.02116.0RegionMembrane-binding domain 1
HgeneNUMA1chr11:71718235chr11:67265793ENST00000393695-21271700_21151821.02116.0RegionNote=Tail (Globular)
HgeneNUMA1chr11:71718235chr11:67265793ENST00000393695-21271882_19851821.02116.0RegionTubulin-binding domain
HgeneNUMA1chr11:71718235chr11:67265793ENST00000393695-21271892_19261821.02116.0RegionGPSM2-binding domain
HgeneNUMA1chr11:71718235chr11:67265793ENST00000393695-21271981_20601821.02116.0RegionMembrane-binding domain 2
TgenePITPNM1chr11:71718234chr11:67265793ENST00000356404924310_319494.66666666666671245.0Compositional biasNote=Poly-Ser
TgenePITPNM1chr11:71718234chr11:67265793ENST00000436757924310_319494.66666666666671244.0Compositional biasNote=Poly-Ser
TgenePITPNM1chr11:71718234chr11:67265793ENST00000534749823310_319494.66666666666671245.0Compositional biasNote=Poly-Ser
TgenePITPNM1chr11:71718235chr11:67265793ENST00000356404924310_319494.66666666666671245.0Compositional biasNote=Poly-Ser
TgenePITPNM1chr11:71718235chr11:67265793ENST00000436757924310_319494.66666666666671244.0Compositional biasNote=Poly-Ser
TgenePITPNM1chr11:71718235chr11:67265793ENST00000534749823310_319494.66666666666671245.0Compositional biasNote=Poly-Ser


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Fusion Gene Sequence for NUMA1-PITPNM1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000358965_ENST00000534749_TCGA-E2-A107-01A_NUMA1_chr11_71718235_-_PITPNM1_chr11_67265793_length(transcript)=8195nt_BP=5679nt
GCCCACGAAGAGGTACGATTCCGGAGAATCGCGAGGCAGAGCGGGAGCGCGCAGCCAGGTGGAAACTAATTCTAAGCCAGACTGCTGGAG
ATCACCCTGTTCTAGTGTGTGGAGGCTTCCACCAGGAGTCTGGAGTGCAATGGCACGATCTCGGCTCACTGCAACCTCCACCTCCCAGGT
TCAAGCGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGCGCATTGGAGTGACTGTCTGGCATCACCAAGATGACACTCCAC
GCCACCCGGGGGGCTGCACTCCTCTCTTGGGTGAACAGTCTACACGTGGCTGACCCTGTGGAGGCTGTGCTGCAGCTCCAGGACTGCAGC
ATCTTCATCAAGATCATTGACAGAATCCATGGCACTGAAGAGGGACAGCAAATCTTGAAGCAGCCGGTGTCAGAGAGACTGGACTTTGTG
TGCAGTTTTCTGCAGAAAAATCGAAAACATCCCTCTTCCCCAGAATGCCTGGTATCTGCACAGAAGGTGCTAGAGGGATCAGAGCTGGAA
CTGGCGAAGATGACCATGCTGCTCTTATACCACTCTACCATGAGCTCCAAAAGTCCCAGGGACTGGGAACAGTTTGAATATAAAATTCAG
GCTGAGTTGGCTGTCATTCTTAAATTTGTGCTGGACCATGAGGACGGGCTAAACCTTAATGAGGACCTAGAGAACTTCCTACAGAAAGCT
CCTGTGCCTTCTACCTGTTCTAGCACATTCCCTGAAGAGCTCTCCCCACCTAGCCACCAGGCCAAGAGGGAGATTCGCTTCCTAGAGCTA
CAGAAGGTTGCCTCCTCTTCCAGTGGGAACAACTTTCTCTCAGGTTCTCCAGCTTCTCCCATGGGTGATATCCTGCAGACCCCACAGTTC
CAGATGAGACGGCTGAAGAAGCAGCTTGCTGATGAGAGAAGTAATAGGGATGAGCTGGAGCTGGAGCTAGCTGAGAACCGCAAGCTCCTC
ACCGAGAAGGATGCACAGATAGCCATGATGCAGCAGCGCATTGACCGCCTAGCCCTGCTGAATGAGAAGCAGGCGGCCAGCCCACTGGAG
CCCAAGGAGCTTGAGGAGCTGCGTGACAAGAATGAGAGCCTTACCATGCGGCTGCATGAAACCCTGAAGCAGTGCCAGGACCTGAAGACA
GAGAAGAGCCAGATGGATCGCAAAATCAACCAGCTTTCGGAGGAGAATGGAGACCTTTCCTTTAAGCTGCGGGAGTTTGCCAGTCATCTG
CAGCAGCTACAGGATGCCCTCAATGAGCTGACGGAGGAGCACAGCAAGGCCACTCAGGAGTGGCTAGAGAAGCAGGCCCAGCTGGAGAAG
GAGCTCAGCGCAGCCCTGCAGGACAAGAAATGCCTTGAAGAGAAGAACGAAATCCTTCAGGGAAAACTTTCACAGCTGGAAGAACACTTG
TCCCAGCTGCAGGATAACCCACCCCAGGAGAAGGGCGAGGTGCTGGGTGATGTCTTGCAGCTGGAAACCTTGAAGCAAGAGGCAGCCACT
CTTGCTGCAAACAACACACAGCTCCAAGCCAGGGTAGAGATGCTGGAGACTGAGCGAGGCCAGCAGGAAGCCAAGCTGCTTGCTGAGCGG
GGCCACTTCGAAGAAGAAAAGCAGCAGCTGTCTAGCCTGATCACTGACCTGCAGAGCTCCATCTCCAACCTCAGCCAGGCCAAGGAAGAG
CTGGAGCAGGCCTCCCAGGCTCATGGGGCCCGGTTGACTGCCCAGGTGGCCTCTCTGACCTCTGAGCTCACCACACTCAATGCCACCATC
CAGCAACAGGATCAAGAACTGGCTGGCCTGAAGCAGCAGGCCAAAGAGAAGCAGGCCCAGCTAGCACAGACCCTCCAACAGCAAGAACAG
GCCTCCCAGGGCCTCCGCCACCAGGTGGAGCAGCTAAGCAGTAGCCTGAAGCAGAAGGAGCAGCAGTTGAAGGAGGTAGCGGAGAAGCAG
GAGGCAACTAGGCAGGACCATGCCCAGCAACTGGCCACTGCTGCAGAGGAGCGAGAGGCCTCCTTAAGGGAGCGGGATGCGGCTCTCAAG
CAGCTGGAGGCACTGGAGAAGGAGAAGGCTGCCAAGCTGGAGATTCTGCAGCAGCAACTTCAGGTGGCTAATGAAGCCCGGGACAGTGCC
CAGACCTCAGTGACACAGGCCCAGCGGGAGAAGGCAGAGCTGAGCCGGAAGGTGGAGGAACTCCAGGCCTGTGTTGAGACAGCCCGCCAG
GAACAGCATGAGGCCCAGGCCCAGGTTGCAGAGCTAGAGTTGCAGCTGCGGTCTGAGCAGCAAAAAGCAACTGAGAAAGAAAGGGTGGCC
CAGGAGAAGGACCAGCTCCAGGAGCAGCTCCAGGCCCTCAAAGAGTCCTTGAAGGTCACCAAGGGCAGCCTTGAAGAGGAGAAGCGCAGG
GCTGCAGATGCCCTGGAAGAGCAGCAGCGTTGTATCTCTGAGCTGAAGGCAGAGACCCGAAGCCTGGTGGAGCAGCATAAGCGGGAACGA
AAGGAGCTGGAAGAAGAGAGGGCTGGGCGCAAGGGGCTGGAGGCTCGATTACAGCAGCTTGGGGAGGCCCATCAGGCTGAGACTGAAGTC
CTGCGGCGGGAGCTGGCAGAGGCCATGGCTGCCCAGCACACAGCTGAGAGTGAGTGTGAGCAGCTCGTCAAAGAAGTAGCTGCCTGGCGT
GAGCGGTATGAGGATAGCCAGCAAGAGGAGGCACAGTATGGCGCCATGTTCCAGGAACAGCTGATGACTTTGAAGGAGGAATGTGAGAAG
GCCCGCCAGGAGCTGCAGGAGGCAAAGGAGAAGGTGGCAGGCATAGAATCCCACAGCGAGCTCCAGATAAGCCGGCAGCAGAACGAACTA
GCTGAGCTCCATGCCAACCTGGCCAGAGCACTCCAGCAGGTCCAAGAGAAGGAAGTCAGGGCCCAGAAGCTTGCAGATGACCTCTCCACT
CTGCAGGAAAAGATGGCTGCCACCAGCAAAGAGGTGGCCCGCTTGGAGACCTTGGTGCGCAAGGCAGGTGAGCAGCAGGAAACAGCCTCC
CGGGAGTTAGTCAAGGAGCCTGCGAGGGCAGGAGACAGACAGCCCGAGTGGCTGGAAGAGCAACAGGGACGCCAGTTCTGCAGCACACAG
GCAGCGCTGCAGGCTATGGAGCGGGAGGCAGAGCAGATGGGCAATGAGCTGGAACGGCTGCGGGCCGCGCTGATGGAGAGCCAGGGGCAG
CAGCAGGAGGAGCGTGGGCAGCAGGAAAGGGAGGTGGCGCGGCTGACCCAGGAGCGGGGCCGTGCCCAGGCTGACCTTGCCCTGGAGAAG
GCGGCCAGAGCAGAGCTTGAGATGCGGCTGCAGAACGCCCTCAACGAGCAGCGTGTGGAGTTCGCTACCCTGCAAGAGGCACTGGCTCAT
GCCCTGACGGAAAAGGAAGGCAAGGACCAGGAGTTGGCCAAGCTTCGTGGTCTGGAGGCAGCCCAGATAAAAGAGCTGGAGGAACTTCGG
CAAACCGTGAAGCAACTGAAGGAACAGCTGGCTAAGAAAGAAAAGGAGCACGCATCTGGCTCAGGAGCCCAATCTGAGGCTGCTGGCAGG
ACAGAGCCAACAGGCCCCAAGCTGGAGGCACTGCGGGCAGAGGTGAGCAAGCTGGAACAGCAATGCCAGAAGCAGCAGGAGCAGGCTGAC
AGCCTGGAACGCAGCCTCGAGGCTGAGCGGGCCTCCCGGGCTGAGCGGGACAGTGCTCTGGAGACTCTGCAGGGCCAGTTAGAGGAGAAG
GCCCAGGAGCTAGGGCACAGTCAGAGTGCCTTAGCCTCGGCCCAACGGGAGTTGGCTGCCTTCCGCACCAAGGTACAAGACCACAGCAAG
GCTGAAGATGAGTGGAAGGCCCAGGTGGCCCGGGGCCGGCAAGAGGCTGAGAGGAAAAATAGCCTCATCAGCAGCTTGGAGGAGGAGGTG
TCCATCCTGAATCGCCAGGTCCTGGAGAAGGAGGGGGAGAGCAAGGAGTTGAAGCGGCTGGTGATGGCCGAGTCAGAGAAGAGCCAGAAG
CTGGAGGAGAGGCTGCGCCTGCTGCAGGCAGAGACAGCCAGCAACAGTGCCAGAGCTGCAGAACGCAGCTCTGCTCTGCGGGAGGAGGTG
CAGAGCCTCCGGGAGGAGGCTGAGAAACAGCGGGTGGCTTCAGAGAACCTGCGGCAGGAGCTGACCTCACAGGCTGAGCGTGCGGAGGAG
CTGGGCCAAGAATTGAAGGCGTGGCAGGAGAAGTTCTTCCAGAAAGAGCAGGCCCTCTCCACCCTGCAGCTCGAGCACACCAGCACACAG
GCCCTGGTGAGTGAGCTGCTGCCAGCTAAGCACCTCTGCCAGCAGCTGCAGGCCGAGCAGGCCGCTGCCGAGAAACGCCACCGTGAGGAG
CTGGAGCAGAGCAAGCAGGCCGCTGGGGGACTGCGGGCAGAGCTGCTGCGGGCCCAGCGGGAGCTTGGGGAGCTGATTCCTCTGCGGCAG
AAGGTGGCAGAGCAGGAGCGAACAGCTCAGCAGCTGCGGGCAGAGAAGGCCAGCTATGCAGAGCAGCTGAGCATGCTGAAGAAGGCGCAT
GGCCTGCTGGCAGAGGAGAACCGGGGGCTGGGTGAGCGGGCCAACCTTGGCCGGCAGTTTCTGGAAGTGGAGTTGGACCAGGCCCGGGAG
AAGTATGTCCAAGAGTTGGCAGCCGTACGTGCTGATGCTGAGACCCGTCTGGCTGAGGTGCAGCGAGAAGCACAGAGCACTGCCCGGGAG
CTGGAGGTGATGACTGCCAAGTATGAGGGTGCCAAGGTCAAGGTCCTGGAGGAGAGGCAGCGGTTCCAGGAAGAGAGGCAGAAACTCACT
GCCCAGGTGGAAGAACTGAGTAAGAAACTGGCTGACTCTGACCAAGCCAGCAAGGTGCAGCAGCAGAAGCTGAAGGCTGTCCAGGCTCAG
GGAGGCGAGAGCCAGCAGGAGGCCCAGCGCCTCCAGGCCCAGCTGAATGAACTGCAAGCCCAGTTGAGCCAGAAGGAGCAGGCAGCTGAG
CACTATAAGCTGCAGATGGAGAAAGCCAAAACACATTATGATGCCAAGAAGCAGCAGAACCAAGAGCTGCAGGAGCAGCTGCGGAGCCTG
GAGCAGCTGCAGAAGGAAAACAAAGAGCTGCGAGCTGAAGCTGAACGGCTGGGCCATGAGCTACAGCAGGCTGGGCTGAAGACCAAGGAG
GCTGAACAGACCTGCCGCCACCTTACTGCCCAGGTGCGCAGCCTGGAGGCACAGGTTGCCCATGCAGACCAGCAGCTTCGAGACCTGGGC
AAATTCCAGGTGGCAACTGATGCTTTAAAGAGCCGTGAGCCCCAGGCTAAGCCCCAGCTGGACTTGAGTATTGACAGCCTGGATCTGAGC
TGCGAGGAGGGGACCCCACTCAGTATCACCAGCAAGCTGCCTCGTACCCAGCCAGACGGCACCAGCGTCCCTGGAGAACCAGCCTCACCT
ATCTCCCAGCGCCTGCCCCCCAAGGTAGAATCCCTGGAGAGTCTCTACTTCACTCCCATCCCTGCTCGGAGTCAGGCCCCCCTGGAGAGC
AGCCTGGACTCCCTGGGAGACGTCTTCCTGGACTCGGGTCGTAAGACCCGCTCCGCTCGTCGGCGCACCACGCAGATCATCAACATCACC
ATGACCAAGCCTGAGCCCTTACAGCCACGATGGGGACAGCCTGTCTCGCTCCCAAGACCACATTCCACTGGCTGCCCTGCCACTGCTGGC
CACCTCATCCTCCCGCTACCAGGGCGCCGTGGCCACCGTCATTGCCCGCACCAACCAGGCCTACTCAGCCTTCCTGCGCTCACCTGAGGG
TGCCGGCTTCTGTGGGCAGGTCGCACTGATTGGAGATGGTGTTGGTGGCATCCTGGGCTTTGATGCACTCTGCCACAGTGCTAACGCGGG
CACCGGGAGTCGGGGCAGCAGCCGCCGTGGGAGCATGAACAATGAGCTGCTCTCTCCGGAGTTTGGCCCAGTGCGGGACCCCCTGGCAGA
TGGTGTGGAAGGCCTGGGTCGGGGCAGCCCAGAACCCTCGGCCTTGCCTCCCCAGCGCATCCCCAGCGACATGGCCAGTCCTGAGCCCGA
GGGCTCTCAGAACAGCCTTCAGGCAGCCCCCGCAACCACCTCCTCCTGGGAGCCCCGGCGGGCAAGCACGGCCTTCTGCCCACCCGCTGC
CAGTTCCGAGGCACCTGACGGCCCCAGCAGCACTGCCCGCCTTGACTTCAAGGTCTCTGGCTTCTTCCTCTTCGGCTCCCCACTGGGCCT
GGTGCTGGCTCTGCGCAAAACTGTGATGCCCGCCCTGGAGGCAGCCCAGATGCGCCCAGCCTGTGAACAGATCTACAACCTCTTCCACGC
GGCTGACCCCTGCGCCTCACGCCTCGAGCCCCTGCTGGCCCCGAAGTTCCAGGCCATCGCCCCACTGACCGTGCCCCGCTACCAGAAGTT
CCCCCTGGGAGATGGCTCATCCCTGCTGCTGGCCGACACTCTGCAGACGCACTCCAGCCTCTTTCTGGAGGAGCTGGAGATGCTGGTGCC
CTCAACACCCACCTCTACTAGCGGTGCCTTCTGGAAGGGCAGTGAGTTGGCCACTGACCCCCCGGCCCAGCCAGCCGCCCCCAGCACCAC
CAGTGAGGTGGTTAAGATCCTGGAGCGCTGGTGGGGGACCAAGCGGATCGACTACTCGCTGTACTGCCCCGAGGCGCTCACCGCCTTTCC
CACCGTCACGCTGCCCCACCTCTTCCACGCCAGCTACTGGGAGTCCGCCGACGTGGTGGCGTTCATCCTGCGCCAGGTGATCGAGAAGGA
GCGGCCACAGCTGGCGGAATGCGAGGAGCCGTCCATCTACAGCCCGGCCTTCCCCAGGGAGAAGTGGCAGCGAAAACGCACGCAGGTCAA
GATCCGGAACGTCACTTCCAACCACCGGGCGAGCGACACGGTGGTGTGCGAGGGCCGCCCCCAGGTGCTAAGCGGGCGCTTCATGTACGG
GCCCCTGGACGTCGTCACGCTCACTGGAGAGAAGGTGGATGTCTACATCATGACGCAGCCGCTGTCGGGCAAGTGGATCCACTTTGGCAC
CGAAGTCACCAATAGCTCGGGCCGCCTCACCTTCCCAGTTCCCCCAGAACGCGCGCTGGGCATTGGTGTCTACCCCGTGCGCATGGTGGT
CAGGGGCGACCACACCTATGCCGAATGCTGCCTGACTGTGGTGGCCCGCGGCACGGAGGCTGTGGTCTTCAGCATCGACGGCTCCTTCAC
CGCCAGCGTCTCCATCATGGGCAGCGACCCCAAGGTGCGAGCTGGCGCCGTGGACGTGGTCAGGCACTGGCAGGACTCCGGCTACCTGAT
CGTGTATGTCACAGGCCGGCCGGATATGCAGAAGCACCGCGTGGTGGCATGGCTGTCGCAGCACAACTTCCCCCACGGCGTCGTCTCCTT
CTGCGACGGCCTCACCCACGACCCACTACGCCAGAAGGCAATGTTTCTGCAGAGCCTGGTGCAGGAGGTAGAACTGAACATCGTGGCCGG
TTATGGGTCTCCCAAAGATGTGGCTGTATACGCGGCGCTGGGGCTGTCCCCGAGCCAGACCTACATCGTGGGCCGTGCCGTGCGGAAGCT
ACAGGCGCAGTGCCAGTTCCTGTCAGACGGCTATGTGGCCCACCTGGGCCAGCTGGAAGCGGGCTCGCACTCGCATGCCTCCTCGGGACC
CCCGAGAGCTGCCTTGGGCAAGAGCAGCTATGGTGTGGCTGCCCCCGTGGACTTCCTGCGCAAACAGAGCCAGCTGCTTCGCTCGAGGGG
CCCCAGCCAGGCGGAGCGTGAGGGCCCGGGAACACCACCCACCACCCTGGCACGGGGCAAAGCACGGAGCATCAGCCTGAAGCTGGACAG
CGAGGAGTGAGGCCCACACCAGCCTGGACCTGGGTTATTTATTGACACACCCAAGGGGCCCGAGGGGCTGCGTGTGGGAGGCTGGGGACC
CAGACTTTTGGCCCCAGCGCTGGCCCCCCCAGCCCCACACCCTATATCTCCGTGTGCTCCTCGGTGTTACTTCCCTTTCATATGAGGGGA
CCCAGCGCCGGGGGGAGGGAGGAGGGCGTGGGCATGGGCGCAGAGGCTTTTCCAGTGTGTATAAATCCATGAAAATAAACGCCACCTGCA

>In-frame_ENST00000358965_ENST00000534749_TCGA-E2-A107-01A_NUMA1_chr11_71718235_-_PITPNM1_chr11_67265793_length(amino acids)=1868AA_start in transcript=240_stop in transcript=5846
MSGITKMTLHATRGAALLSWVNSLHVADPVEAVLQLQDCSIFIKIIDRIHGTEEGQQILKQPVSERLDFVCSFLQKNRKHPSSPECLVSA
QKVLEGSELELAKMTMLLLYHSTMSSKSPRDWEQFEYKIQAELAVILKFVLDHEDGLNLNEDLENFLQKAPVPSTCSSTFPEELSPPSHQ
AKREIRFLELQKVASSSSGNNFLSGSPASPMGDILQTPQFQMRRLKKQLADERSNRDELELELAENRKLLTEKDAQIAMMQQRIDRLALL
NEKQAASPLEPKELEELRDKNESLTMRLHETLKQCQDLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEHSKATQE
WLEKQAQLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVEMLETERG
QQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQ
LAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQL
QVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVT
KGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLGEAHQAETEVLRRELAEAMAAQHTAESECE
QLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKEECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVR
AQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDRQPEWLEEQQGRQFCSTQAALQAMEREAEQMGNELERL
RAALMESQGQQQEERGQQEREVARLTQERGRAQADLALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEA
AQIKELEELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQEQADSLERSLEAERASRAERDSAL
ETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRL
VMAESEKSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAERAEELGQELKAWQEKFFQKEQALS
TLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKASYA
EQLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQ
RFQEERQKLTAQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQN
QELQEQLRSLEQLQKENKELRAEAERLGHELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLGKFQVATDALKSREPQAKPQL
DLSIDSLDLSCEEGTPLSITSKLPRTQPDGTSVPGEPASPISQRLPPKVESLESLYFTPIPARSQAPLESSLDSLGDVFLDSGRKTRSAR

--------------------------------------------------------------
>In-frame_ENST00000358965_ENST00000436757_TCGA-E2-A107-01A_NUMA1_chr11_71718235_-_PITPNM1_chr11_67265793_length(transcript)=8192nt_BP=5679nt
GCCCACGAAGAGGTACGATTCCGGAGAATCGCGAGGCAGAGCGGGAGCGCGCAGCCAGGTGGAAACTAATTCTAAGCCAGACTGCTGGAG
ATCACCCTGTTCTAGTGTGTGGAGGCTTCCACCAGGAGTCTGGAGTGCAATGGCACGATCTCGGCTCACTGCAACCTCCACCTCCCAGGT
TCAAGCGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGCGCATTGGAGTGACTGTCTGGCATCACCAAGATGACACTCCAC
GCCACCCGGGGGGCTGCACTCCTCTCTTGGGTGAACAGTCTACACGTGGCTGACCCTGTGGAGGCTGTGCTGCAGCTCCAGGACTGCAGC
ATCTTCATCAAGATCATTGACAGAATCCATGGCACTGAAGAGGGACAGCAAATCTTGAAGCAGCCGGTGTCAGAGAGACTGGACTTTGTG
TGCAGTTTTCTGCAGAAAAATCGAAAACATCCCTCTTCCCCAGAATGCCTGGTATCTGCACAGAAGGTGCTAGAGGGATCAGAGCTGGAA
CTGGCGAAGATGACCATGCTGCTCTTATACCACTCTACCATGAGCTCCAAAAGTCCCAGGGACTGGGAACAGTTTGAATATAAAATTCAG
GCTGAGTTGGCTGTCATTCTTAAATTTGTGCTGGACCATGAGGACGGGCTAAACCTTAATGAGGACCTAGAGAACTTCCTACAGAAAGCT
CCTGTGCCTTCTACCTGTTCTAGCACATTCCCTGAAGAGCTCTCCCCACCTAGCCACCAGGCCAAGAGGGAGATTCGCTTCCTAGAGCTA
CAGAAGGTTGCCTCCTCTTCCAGTGGGAACAACTTTCTCTCAGGTTCTCCAGCTTCTCCCATGGGTGATATCCTGCAGACCCCACAGTTC
CAGATGAGACGGCTGAAGAAGCAGCTTGCTGATGAGAGAAGTAATAGGGATGAGCTGGAGCTGGAGCTAGCTGAGAACCGCAAGCTCCTC
ACCGAGAAGGATGCACAGATAGCCATGATGCAGCAGCGCATTGACCGCCTAGCCCTGCTGAATGAGAAGCAGGCGGCCAGCCCACTGGAG
CCCAAGGAGCTTGAGGAGCTGCGTGACAAGAATGAGAGCCTTACCATGCGGCTGCATGAAACCCTGAAGCAGTGCCAGGACCTGAAGACA
GAGAAGAGCCAGATGGATCGCAAAATCAACCAGCTTTCGGAGGAGAATGGAGACCTTTCCTTTAAGCTGCGGGAGTTTGCCAGTCATCTG
CAGCAGCTACAGGATGCCCTCAATGAGCTGACGGAGGAGCACAGCAAGGCCACTCAGGAGTGGCTAGAGAAGCAGGCCCAGCTGGAGAAG
GAGCTCAGCGCAGCCCTGCAGGACAAGAAATGCCTTGAAGAGAAGAACGAAATCCTTCAGGGAAAACTTTCACAGCTGGAAGAACACTTG
TCCCAGCTGCAGGATAACCCACCCCAGGAGAAGGGCGAGGTGCTGGGTGATGTCTTGCAGCTGGAAACCTTGAAGCAAGAGGCAGCCACT
CTTGCTGCAAACAACACACAGCTCCAAGCCAGGGTAGAGATGCTGGAGACTGAGCGAGGCCAGCAGGAAGCCAAGCTGCTTGCTGAGCGG
GGCCACTTCGAAGAAGAAAAGCAGCAGCTGTCTAGCCTGATCACTGACCTGCAGAGCTCCATCTCCAACCTCAGCCAGGCCAAGGAAGAG
CTGGAGCAGGCCTCCCAGGCTCATGGGGCCCGGTTGACTGCCCAGGTGGCCTCTCTGACCTCTGAGCTCACCACACTCAATGCCACCATC
CAGCAACAGGATCAAGAACTGGCTGGCCTGAAGCAGCAGGCCAAAGAGAAGCAGGCCCAGCTAGCACAGACCCTCCAACAGCAAGAACAG
GCCTCCCAGGGCCTCCGCCACCAGGTGGAGCAGCTAAGCAGTAGCCTGAAGCAGAAGGAGCAGCAGTTGAAGGAGGTAGCGGAGAAGCAG
GAGGCAACTAGGCAGGACCATGCCCAGCAACTGGCCACTGCTGCAGAGGAGCGAGAGGCCTCCTTAAGGGAGCGGGATGCGGCTCTCAAG
CAGCTGGAGGCACTGGAGAAGGAGAAGGCTGCCAAGCTGGAGATTCTGCAGCAGCAACTTCAGGTGGCTAATGAAGCCCGGGACAGTGCC
CAGACCTCAGTGACACAGGCCCAGCGGGAGAAGGCAGAGCTGAGCCGGAAGGTGGAGGAACTCCAGGCCTGTGTTGAGACAGCCCGCCAG
GAACAGCATGAGGCCCAGGCCCAGGTTGCAGAGCTAGAGTTGCAGCTGCGGTCTGAGCAGCAAAAAGCAACTGAGAAAGAAAGGGTGGCC
CAGGAGAAGGACCAGCTCCAGGAGCAGCTCCAGGCCCTCAAAGAGTCCTTGAAGGTCACCAAGGGCAGCCTTGAAGAGGAGAAGCGCAGG
GCTGCAGATGCCCTGGAAGAGCAGCAGCGTTGTATCTCTGAGCTGAAGGCAGAGACCCGAAGCCTGGTGGAGCAGCATAAGCGGGAACGA
AAGGAGCTGGAAGAAGAGAGGGCTGGGCGCAAGGGGCTGGAGGCTCGATTACAGCAGCTTGGGGAGGCCCATCAGGCTGAGACTGAAGTC
CTGCGGCGGGAGCTGGCAGAGGCCATGGCTGCCCAGCACACAGCTGAGAGTGAGTGTGAGCAGCTCGTCAAAGAAGTAGCTGCCTGGCGT
GAGCGGTATGAGGATAGCCAGCAAGAGGAGGCACAGTATGGCGCCATGTTCCAGGAACAGCTGATGACTTTGAAGGAGGAATGTGAGAAG
GCCCGCCAGGAGCTGCAGGAGGCAAAGGAGAAGGTGGCAGGCATAGAATCCCACAGCGAGCTCCAGATAAGCCGGCAGCAGAACGAACTA
GCTGAGCTCCATGCCAACCTGGCCAGAGCACTCCAGCAGGTCCAAGAGAAGGAAGTCAGGGCCCAGAAGCTTGCAGATGACCTCTCCACT
CTGCAGGAAAAGATGGCTGCCACCAGCAAAGAGGTGGCCCGCTTGGAGACCTTGGTGCGCAAGGCAGGTGAGCAGCAGGAAACAGCCTCC
CGGGAGTTAGTCAAGGAGCCTGCGAGGGCAGGAGACAGACAGCCCGAGTGGCTGGAAGAGCAACAGGGACGCCAGTTCTGCAGCACACAG
GCAGCGCTGCAGGCTATGGAGCGGGAGGCAGAGCAGATGGGCAATGAGCTGGAACGGCTGCGGGCCGCGCTGATGGAGAGCCAGGGGCAG
CAGCAGGAGGAGCGTGGGCAGCAGGAAAGGGAGGTGGCGCGGCTGACCCAGGAGCGGGGCCGTGCCCAGGCTGACCTTGCCCTGGAGAAG
GCGGCCAGAGCAGAGCTTGAGATGCGGCTGCAGAACGCCCTCAACGAGCAGCGTGTGGAGTTCGCTACCCTGCAAGAGGCACTGGCTCAT
GCCCTGACGGAAAAGGAAGGCAAGGACCAGGAGTTGGCCAAGCTTCGTGGTCTGGAGGCAGCCCAGATAAAAGAGCTGGAGGAACTTCGG
CAAACCGTGAAGCAACTGAAGGAACAGCTGGCTAAGAAAGAAAAGGAGCACGCATCTGGCTCAGGAGCCCAATCTGAGGCTGCTGGCAGG
ACAGAGCCAACAGGCCCCAAGCTGGAGGCACTGCGGGCAGAGGTGAGCAAGCTGGAACAGCAATGCCAGAAGCAGCAGGAGCAGGCTGAC
AGCCTGGAACGCAGCCTCGAGGCTGAGCGGGCCTCCCGGGCTGAGCGGGACAGTGCTCTGGAGACTCTGCAGGGCCAGTTAGAGGAGAAG
GCCCAGGAGCTAGGGCACAGTCAGAGTGCCTTAGCCTCGGCCCAACGGGAGTTGGCTGCCTTCCGCACCAAGGTACAAGACCACAGCAAG
GCTGAAGATGAGTGGAAGGCCCAGGTGGCCCGGGGCCGGCAAGAGGCTGAGAGGAAAAATAGCCTCATCAGCAGCTTGGAGGAGGAGGTG
TCCATCCTGAATCGCCAGGTCCTGGAGAAGGAGGGGGAGAGCAAGGAGTTGAAGCGGCTGGTGATGGCCGAGTCAGAGAAGAGCCAGAAG
CTGGAGGAGAGGCTGCGCCTGCTGCAGGCAGAGACAGCCAGCAACAGTGCCAGAGCTGCAGAACGCAGCTCTGCTCTGCGGGAGGAGGTG
CAGAGCCTCCGGGAGGAGGCTGAGAAACAGCGGGTGGCTTCAGAGAACCTGCGGCAGGAGCTGACCTCACAGGCTGAGCGTGCGGAGGAG
CTGGGCCAAGAATTGAAGGCGTGGCAGGAGAAGTTCTTCCAGAAAGAGCAGGCCCTCTCCACCCTGCAGCTCGAGCACACCAGCACACAG
GCCCTGGTGAGTGAGCTGCTGCCAGCTAAGCACCTCTGCCAGCAGCTGCAGGCCGAGCAGGCCGCTGCCGAGAAACGCCACCGTGAGGAG
CTGGAGCAGAGCAAGCAGGCCGCTGGGGGACTGCGGGCAGAGCTGCTGCGGGCCCAGCGGGAGCTTGGGGAGCTGATTCCTCTGCGGCAG
AAGGTGGCAGAGCAGGAGCGAACAGCTCAGCAGCTGCGGGCAGAGAAGGCCAGCTATGCAGAGCAGCTGAGCATGCTGAAGAAGGCGCAT
GGCCTGCTGGCAGAGGAGAACCGGGGGCTGGGTGAGCGGGCCAACCTTGGCCGGCAGTTTCTGGAAGTGGAGTTGGACCAGGCCCGGGAG
AAGTATGTCCAAGAGTTGGCAGCCGTACGTGCTGATGCTGAGACCCGTCTGGCTGAGGTGCAGCGAGAAGCACAGAGCACTGCCCGGGAG
CTGGAGGTGATGACTGCCAAGTATGAGGGTGCCAAGGTCAAGGTCCTGGAGGAGAGGCAGCGGTTCCAGGAAGAGAGGCAGAAACTCACT
GCCCAGGTGGAAGAACTGAGTAAGAAACTGGCTGACTCTGACCAAGCCAGCAAGGTGCAGCAGCAGAAGCTGAAGGCTGTCCAGGCTCAG
GGAGGCGAGAGCCAGCAGGAGGCCCAGCGCCTCCAGGCCCAGCTGAATGAACTGCAAGCCCAGTTGAGCCAGAAGGAGCAGGCAGCTGAG
CACTATAAGCTGCAGATGGAGAAAGCCAAAACACATTATGATGCCAAGAAGCAGCAGAACCAAGAGCTGCAGGAGCAGCTGCGGAGCCTG
GAGCAGCTGCAGAAGGAAAACAAAGAGCTGCGAGCTGAAGCTGAACGGCTGGGCCATGAGCTACAGCAGGCTGGGCTGAAGACCAAGGAG
GCTGAACAGACCTGCCGCCACCTTACTGCCCAGGTGCGCAGCCTGGAGGCACAGGTTGCCCATGCAGACCAGCAGCTTCGAGACCTGGGC
AAATTCCAGGTGGCAACTGATGCTTTAAAGAGCCGTGAGCCCCAGGCTAAGCCCCAGCTGGACTTGAGTATTGACAGCCTGGATCTGAGC
TGCGAGGAGGGGACCCCACTCAGTATCACCAGCAAGCTGCCTCGTACCCAGCCAGACGGCACCAGCGTCCCTGGAGAACCAGCCTCACCT
ATCTCCCAGCGCCTGCCCCCCAAGGTAGAATCCCTGGAGAGTCTCTACTTCACTCCCATCCCTGCTCGGAGTCAGGCCCCCCTGGAGAGC
AGCCTGGACTCCCTGGGAGACGTCTTCCTGGACTCGGGTCGTAAGACCCGCTCCGCTCGTCGGCGCACCACGCAGATCATCAACATCACC
ATGACCAAGCCTGAGCCCTTACAGCCACGATGGGGACAGCCTGTCTCGCTCCCAAGACCACATTCCACTGGCTGCCCTGCCACTGCTGGC
CACCTCATCCTCCCGCTACCAGGGCGCCGTGGCCACCGTCATTGCCCGCACCAACCAGGCCTACTCAGCCTTCCTGCGCTCACCTGAGGG
TGCCGGCTTCTGTGGGCAGGTCGCACTGATTGGAGATGGTGTTGGTGGCATCCTGGGCTTTGATGCACTCTGCCACAGTGCTAACGCGGG
CACCGGGAGTCGGGGCAGCAGCCGCCGTGGGAGCATGAACAATGAGCTGCTCTCTCCGGAGTTTGGCCCAGTGCGGGACCCCCTGGCAGA
TGGTGTGGAAGGCCTGGGTCGGGGCAGCCCAGAACCCTCGGCCTTGCCTCCCCAGCGCATCCCCAGCGACATGGCCAGTCCTGAGCCCGA
GGGCTCTCAGAACAGCCTTCAGGCAGCCCCCGCAACCACCTCCTCCTGGGAGCCCCGGCGGGCAAGCACGGCCTTCTGCCCACCCGCTGC
CAGTTCCGAGGCACCTGACGGCCCCAGCAGCACTGCCCGCCTTGACTTCAAGGTCTCTGGCTTCTTCCTCTTCGGCTCCCCACTGGGCCT
GGTGCTGGCTCTGCGCAAAACTGTGATGCCCGCCCTGGAGGCCCAGATGCGCCCAGCCTGTGAACAGATCTACAACCTCTTCCACGCGGC
TGACCCCTGCGCCTCACGCCTCGAGCCCCTGCTGGCCCCGAAGTTCCAGGCCATCGCCCCACTGACCGTGCCCCGCTACCAGAAGTTCCC
CCTGGGAGATGGCTCATCCCTGCTGCTGGCCGACACTCTGCAGACGCACTCCAGCCTCTTTCTGGAGGAGCTGGAGATGCTGGTGCCCTC
AACACCCACCTCTACTAGCGGTGCCTTCTGGAAGGGCAGTGAGTTGGCCACTGACCCCCCGGCCCAGCCAGCCGCCCCCAGCACCACCAG
TGAGGTGGTTAAGATCCTGGAGCGCTGGTGGGGGACCAAGCGGATCGACTACTCGCTGTACTGCCCCGAGGCGCTCACCGCCTTTCCCAC
CGTCACGCTGCCCCACCTCTTCCACGCCAGCTACTGGGAGTCCGCCGACGTGGTGGCGTTCATCCTGCGCCAGGTGATCGAGAAGGAGCG
GCCACAGCTGGCGGAATGCGAGGAGCCGTCCATCTACAGCCCGGCCTTCCCCAGGGAGAAGTGGCAGCGAAAACGCACGCAGGTCAAGAT
CCGGAACGTCACTTCCAACCACCGGGCGAGCGACACGGTGGTGTGCGAGGGCCGCCCCCAGGTGCTAAGCGGGCGCTTCATGTACGGGCC
CCTGGACGTCGTCACGCTCACTGGAGAGAAGGTGGATGTCTACATCATGACGCAGCCGCTGTCGGGCAAGTGGATCCACTTTGGCACCGA
AGTCACCAATAGCTCGGGCCGCCTCACCTTCCCAGTTCCCCCAGAACGCGCGCTGGGCATTGGTGTCTACCCCGTGCGCATGGTGGTCAG
GGGCGACCACACCTATGCCGAATGCTGCCTGACTGTGGTGGCCCGCGGCACGGAGGCTGTGGTCTTCAGCATCGACGGCTCCTTCACCGC
CAGCGTCTCCATCATGGGCAGCGACCCCAAGGTGCGAGCTGGCGCCGTGGACGTGGTCAGGCACTGGCAGGACTCCGGCTACCTGATCGT
GTATGTCACAGGCCGGCCGGATATGCAGAAGCACCGCGTGGTGGCATGGCTGTCGCAGCACAACTTCCCCCACGGCGTCGTCTCCTTCTG
CGACGGCCTCACCCACGACCCACTACGCCAGAAGGCAATGTTTCTGCAGAGCCTGGTGCAGGAGGTAGAACTGAACATCGTGGCCGGTTA
TGGGTCTCCCAAAGATGTGGCTGTATACGCGGCGCTGGGGCTGTCCCCGAGCCAGACCTACATCGTGGGCCGTGCCGTGCGGAAGCTACA
GGCGCAGTGCCAGTTCCTGTCAGACGGCTATGTGGCCCACCTGGGCCAGCTGGAAGCGGGCTCGCACTCGCATGCCTCCTCGGGACCCCC
GAGAGCTGCCTTGGGCAAGAGCAGCTATGGTGTGGCTGCCCCCGTGGACTTCCTGCGCAAACAGAGCCAGCTGCTTCGCTCGAGGGGCCC
CAGCCAGGCGGAGCGTGAGGGCCCGGGAACACCACCCACCACCCTGGCACGGGGCAAAGCACGGAGCATCAGCCTGAAGCTGGACAGCGA
GGAGTGAGGCCCACACCAGCCTGGACCTGGGTTATTTATTGACACACCCAAGGGGCCCGAGGGGCTGCGTGTGGGAGGCTGGGGACCCAG
ACTTTTGGCCCCAGCGCTGGCCCCCCCAGCCCCACACCCTATATCTCCGTGTGCTCCTCGGTGTTACTTCCCTTTCATATGAGGGGACCC
AGCGCCGGGGGGAGGGAGGAGGGCGTGGGCATGGGCGCAGAGGCTTTTCCAGTGTGTATAAATCCATGAAAATAAACGCCACCTGCACCC

>In-frame_ENST00000358965_ENST00000436757_TCGA-E2-A107-01A_NUMA1_chr11_71718235_-_PITPNM1_chr11_67265793_length(amino acids)=1868AA_start in transcript=240_stop in transcript=5846
MSGITKMTLHATRGAALLSWVNSLHVADPVEAVLQLQDCSIFIKIIDRIHGTEEGQQILKQPVSERLDFVCSFLQKNRKHPSSPECLVSA
QKVLEGSELELAKMTMLLLYHSTMSSKSPRDWEQFEYKIQAELAVILKFVLDHEDGLNLNEDLENFLQKAPVPSTCSSTFPEELSPPSHQ
AKREIRFLELQKVASSSSGNNFLSGSPASPMGDILQTPQFQMRRLKKQLADERSNRDELELELAENRKLLTEKDAQIAMMQQRIDRLALL
NEKQAASPLEPKELEELRDKNESLTMRLHETLKQCQDLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEHSKATQE
WLEKQAQLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVEMLETERG
QQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQ
LAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQL
QVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVT
KGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLGEAHQAETEVLRRELAEAMAAQHTAESECE
QLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKEECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVR
AQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDRQPEWLEEQQGRQFCSTQAALQAMEREAEQMGNELERL
RAALMESQGQQQEERGQQEREVARLTQERGRAQADLALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEA
AQIKELEELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQEQADSLERSLEAERASRAERDSAL
ETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRL
VMAESEKSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAERAEELGQELKAWQEKFFQKEQALS
TLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKASYA
EQLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQ
RFQEERQKLTAQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQN
QELQEQLRSLEQLQKENKELRAEAERLGHELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLGKFQVATDALKSREPQAKPQL
DLSIDSLDLSCEEGTPLSITSKLPRTQPDGTSVPGEPASPISQRLPPKVESLESLYFTPIPARSQAPLESSLDSLGDVFLDSGRKTRSAR

--------------------------------------------------------------
>In-frame_ENST00000358965_ENST00000356404_TCGA-E2-A107-01A_NUMA1_chr11_71718235_-_PITPNM1_chr11_67265793_length(transcript)=8194nt_BP=5679nt
GCCCACGAAGAGGTACGATTCCGGAGAATCGCGAGGCAGAGCGGGAGCGCGCAGCCAGGTGGAAACTAATTCTAAGCCAGACTGCTGGAG
ATCACCCTGTTCTAGTGTGTGGAGGCTTCCACCAGGAGTCTGGAGTGCAATGGCACGATCTCGGCTCACTGCAACCTCCACCTCCCAGGT
TCAAGCGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGCGCATTGGAGTGACTGTCTGGCATCACCAAGATGACACTCCAC
GCCACCCGGGGGGCTGCACTCCTCTCTTGGGTGAACAGTCTACACGTGGCTGACCCTGTGGAGGCTGTGCTGCAGCTCCAGGACTGCAGC
ATCTTCATCAAGATCATTGACAGAATCCATGGCACTGAAGAGGGACAGCAAATCTTGAAGCAGCCGGTGTCAGAGAGACTGGACTTTGTG
TGCAGTTTTCTGCAGAAAAATCGAAAACATCCCTCTTCCCCAGAATGCCTGGTATCTGCACAGAAGGTGCTAGAGGGATCAGAGCTGGAA
CTGGCGAAGATGACCATGCTGCTCTTATACCACTCTACCATGAGCTCCAAAAGTCCCAGGGACTGGGAACAGTTTGAATATAAAATTCAG
GCTGAGTTGGCTGTCATTCTTAAATTTGTGCTGGACCATGAGGACGGGCTAAACCTTAATGAGGACCTAGAGAACTTCCTACAGAAAGCT
CCTGTGCCTTCTACCTGTTCTAGCACATTCCCTGAAGAGCTCTCCCCACCTAGCCACCAGGCCAAGAGGGAGATTCGCTTCCTAGAGCTA
CAGAAGGTTGCCTCCTCTTCCAGTGGGAACAACTTTCTCTCAGGTTCTCCAGCTTCTCCCATGGGTGATATCCTGCAGACCCCACAGTTC
CAGATGAGACGGCTGAAGAAGCAGCTTGCTGATGAGAGAAGTAATAGGGATGAGCTGGAGCTGGAGCTAGCTGAGAACCGCAAGCTCCTC
ACCGAGAAGGATGCACAGATAGCCATGATGCAGCAGCGCATTGACCGCCTAGCCCTGCTGAATGAGAAGCAGGCGGCCAGCCCACTGGAG
CCCAAGGAGCTTGAGGAGCTGCGTGACAAGAATGAGAGCCTTACCATGCGGCTGCATGAAACCCTGAAGCAGTGCCAGGACCTGAAGACA
GAGAAGAGCCAGATGGATCGCAAAATCAACCAGCTTTCGGAGGAGAATGGAGACCTTTCCTTTAAGCTGCGGGAGTTTGCCAGTCATCTG
CAGCAGCTACAGGATGCCCTCAATGAGCTGACGGAGGAGCACAGCAAGGCCACTCAGGAGTGGCTAGAGAAGCAGGCCCAGCTGGAGAAG
GAGCTCAGCGCAGCCCTGCAGGACAAGAAATGCCTTGAAGAGAAGAACGAAATCCTTCAGGGAAAACTTTCACAGCTGGAAGAACACTTG
TCCCAGCTGCAGGATAACCCACCCCAGGAGAAGGGCGAGGTGCTGGGTGATGTCTTGCAGCTGGAAACCTTGAAGCAAGAGGCAGCCACT
CTTGCTGCAAACAACACACAGCTCCAAGCCAGGGTAGAGATGCTGGAGACTGAGCGAGGCCAGCAGGAAGCCAAGCTGCTTGCTGAGCGG
GGCCACTTCGAAGAAGAAAAGCAGCAGCTGTCTAGCCTGATCACTGACCTGCAGAGCTCCATCTCCAACCTCAGCCAGGCCAAGGAAGAG
CTGGAGCAGGCCTCCCAGGCTCATGGGGCCCGGTTGACTGCCCAGGTGGCCTCTCTGACCTCTGAGCTCACCACACTCAATGCCACCATC
CAGCAACAGGATCAAGAACTGGCTGGCCTGAAGCAGCAGGCCAAAGAGAAGCAGGCCCAGCTAGCACAGACCCTCCAACAGCAAGAACAG
GCCTCCCAGGGCCTCCGCCACCAGGTGGAGCAGCTAAGCAGTAGCCTGAAGCAGAAGGAGCAGCAGTTGAAGGAGGTAGCGGAGAAGCAG
GAGGCAACTAGGCAGGACCATGCCCAGCAACTGGCCACTGCTGCAGAGGAGCGAGAGGCCTCCTTAAGGGAGCGGGATGCGGCTCTCAAG
CAGCTGGAGGCACTGGAGAAGGAGAAGGCTGCCAAGCTGGAGATTCTGCAGCAGCAACTTCAGGTGGCTAATGAAGCCCGGGACAGTGCC
CAGACCTCAGTGACACAGGCCCAGCGGGAGAAGGCAGAGCTGAGCCGGAAGGTGGAGGAACTCCAGGCCTGTGTTGAGACAGCCCGCCAG
GAACAGCATGAGGCCCAGGCCCAGGTTGCAGAGCTAGAGTTGCAGCTGCGGTCTGAGCAGCAAAAAGCAACTGAGAAAGAAAGGGTGGCC
CAGGAGAAGGACCAGCTCCAGGAGCAGCTCCAGGCCCTCAAAGAGTCCTTGAAGGTCACCAAGGGCAGCCTTGAAGAGGAGAAGCGCAGG
GCTGCAGATGCCCTGGAAGAGCAGCAGCGTTGTATCTCTGAGCTGAAGGCAGAGACCCGAAGCCTGGTGGAGCAGCATAAGCGGGAACGA
AAGGAGCTGGAAGAAGAGAGGGCTGGGCGCAAGGGGCTGGAGGCTCGATTACAGCAGCTTGGGGAGGCCCATCAGGCTGAGACTGAAGTC
CTGCGGCGGGAGCTGGCAGAGGCCATGGCTGCCCAGCACACAGCTGAGAGTGAGTGTGAGCAGCTCGTCAAAGAAGTAGCTGCCTGGCGT
GAGCGGTATGAGGATAGCCAGCAAGAGGAGGCACAGTATGGCGCCATGTTCCAGGAACAGCTGATGACTTTGAAGGAGGAATGTGAGAAG
GCCCGCCAGGAGCTGCAGGAGGCAAAGGAGAAGGTGGCAGGCATAGAATCCCACAGCGAGCTCCAGATAAGCCGGCAGCAGAACGAACTA
GCTGAGCTCCATGCCAACCTGGCCAGAGCACTCCAGCAGGTCCAAGAGAAGGAAGTCAGGGCCCAGAAGCTTGCAGATGACCTCTCCACT
CTGCAGGAAAAGATGGCTGCCACCAGCAAAGAGGTGGCCCGCTTGGAGACCTTGGTGCGCAAGGCAGGTGAGCAGCAGGAAACAGCCTCC
CGGGAGTTAGTCAAGGAGCCTGCGAGGGCAGGAGACAGACAGCCCGAGTGGCTGGAAGAGCAACAGGGACGCCAGTTCTGCAGCACACAG
GCAGCGCTGCAGGCTATGGAGCGGGAGGCAGAGCAGATGGGCAATGAGCTGGAACGGCTGCGGGCCGCGCTGATGGAGAGCCAGGGGCAG
CAGCAGGAGGAGCGTGGGCAGCAGGAAAGGGAGGTGGCGCGGCTGACCCAGGAGCGGGGCCGTGCCCAGGCTGACCTTGCCCTGGAGAAG
GCGGCCAGAGCAGAGCTTGAGATGCGGCTGCAGAACGCCCTCAACGAGCAGCGTGTGGAGTTCGCTACCCTGCAAGAGGCACTGGCTCAT
GCCCTGACGGAAAAGGAAGGCAAGGACCAGGAGTTGGCCAAGCTTCGTGGTCTGGAGGCAGCCCAGATAAAAGAGCTGGAGGAACTTCGG
CAAACCGTGAAGCAACTGAAGGAACAGCTGGCTAAGAAAGAAAAGGAGCACGCATCTGGCTCAGGAGCCCAATCTGAGGCTGCTGGCAGG
ACAGAGCCAACAGGCCCCAAGCTGGAGGCACTGCGGGCAGAGGTGAGCAAGCTGGAACAGCAATGCCAGAAGCAGCAGGAGCAGGCTGAC
AGCCTGGAACGCAGCCTCGAGGCTGAGCGGGCCTCCCGGGCTGAGCGGGACAGTGCTCTGGAGACTCTGCAGGGCCAGTTAGAGGAGAAG
GCCCAGGAGCTAGGGCACAGTCAGAGTGCCTTAGCCTCGGCCCAACGGGAGTTGGCTGCCTTCCGCACCAAGGTACAAGACCACAGCAAG
GCTGAAGATGAGTGGAAGGCCCAGGTGGCCCGGGGCCGGCAAGAGGCTGAGAGGAAAAATAGCCTCATCAGCAGCTTGGAGGAGGAGGTG
TCCATCCTGAATCGCCAGGTCCTGGAGAAGGAGGGGGAGAGCAAGGAGTTGAAGCGGCTGGTGATGGCCGAGTCAGAGAAGAGCCAGAAG
CTGGAGGAGAGGCTGCGCCTGCTGCAGGCAGAGACAGCCAGCAACAGTGCCAGAGCTGCAGAACGCAGCTCTGCTCTGCGGGAGGAGGTG
CAGAGCCTCCGGGAGGAGGCTGAGAAACAGCGGGTGGCTTCAGAGAACCTGCGGCAGGAGCTGACCTCACAGGCTGAGCGTGCGGAGGAG
CTGGGCCAAGAATTGAAGGCGTGGCAGGAGAAGTTCTTCCAGAAAGAGCAGGCCCTCTCCACCCTGCAGCTCGAGCACACCAGCACACAG
GCCCTGGTGAGTGAGCTGCTGCCAGCTAAGCACCTCTGCCAGCAGCTGCAGGCCGAGCAGGCCGCTGCCGAGAAACGCCACCGTGAGGAG
CTGGAGCAGAGCAAGCAGGCCGCTGGGGGACTGCGGGCAGAGCTGCTGCGGGCCCAGCGGGAGCTTGGGGAGCTGATTCCTCTGCGGCAG
AAGGTGGCAGAGCAGGAGCGAACAGCTCAGCAGCTGCGGGCAGAGAAGGCCAGCTATGCAGAGCAGCTGAGCATGCTGAAGAAGGCGCAT
GGCCTGCTGGCAGAGGAGAACCGGGGGCTGGGTGAGCGGGCCAACCTTGGCCGGCAGTTTCTGGAAGTGGAGTTGGACCAGGCCCGGGAG
AAGTATGTCCAAGAGTTGGCAGCCGTACGTGCTGATGCTGAGACCCGTCTGGCTGAGGTGCAGCGAGAAGCACAGAGCACTGCCCGGGAG
CTGGAGGTGATGACTGCCAAGTATGAGGGTGCCAAGGTCAAGGTCCTGGAGGAGAGGCAGCGGTTCCAGGAAGAGAGGCAGAAACTCACT
GCCCAGGTGGAAGAACTGAGTAAGAAACTGGCTGACTCTGACCAAGCCAGCAAGGTGCAGCAGCAGAAGCTGAAGGCTGTCCAGGCTCAG
GGAGGCGAGAGCCAGCAGGAGGCCCAGCGCCTCCAGGCCCAGCTGAATGAACTGCAAGCCCAGTTGAGCCAGAAGGAGCAGGCAGCTGAG
CACTATAAGCTGCAGATGGAGAAAGCCAAAACACATTATGATGCCAAGAAGCAGCAGAACCAAGAGCTGCAGGAGCAGCTGCGGAGCCTG
GAGCAGCTGCAGAAGGAAAACAAAGAGCTGCGAGCTGAAGCTGAACGGCTGGGCCATGAGCTACAGCAGGCTGGGCTGAAGACCAAGGAG
GCTGAACAGACCTGCCGCCACCTTACTGCCCAGGTGCGCAGCCTGGAGGCACAGGTTGCCCATGCAGACCAGCAGCTTCGAGACCTGGGC
AAATTCCAGGTGGCAACTGATGCTTTAAAGAGCCGTGAGCCCCAGGCTAAGCCCCAGCTGGACTTGAGTATTGACAGCCTGGATCTGAGC
TGCGAGGAGGGGACCCCACTCAGTATCACCAGCAAGCTGCCTCGTACCCAGCCAGACGGCACCAGCGTCCCTGGAGAACCAGCCTCACCT
ATCTCCCAGCGCCTGCCCCCCAAGGTAGAATCCCTGGAGAGTCTCTACTTCACTCCCATCCCTGCTCGGAGTCAGGCCCCCCTGGAGAGC
AGCCTGGACTCCCTGGGAGACGTCTTCCTGGACTCGGGTCGTAAGACCCGCTCCGCTCGTCGGCGCACCACGCAGATCATCAACATCACC
ATGACCAAGCCTGAGCCCTTACAGCCACGATGGGGACAGCCTGTCTCGCTCCCAAGACCACATTCCACTGGCTGCCCTGCCACTGCTGGC
CACCTCATCCTCCCGCTACCAGGGCGCCGTGGCCACCGTCATTGCCCGCACCAACCAGGCCTACTCAGCCTTCCTGCGCTCACCTGAGGG
TGCCGGCTTCTGTGGGCAGGTCGCACTGATTGGAGATGGTGTTGGTGGCATCCTGGGCTTTGATGCACTCTGCCACAGTGCTAACGCGGG
CACCGGGAGTCGGGGCAGCAGCCGCCGTGGGAGCATGAACAATGAGCTGCTCTCTCCGGAGTTTGGCCCAGTGCGGGACCCCCTGGCAGA
TGGTGTGGAAGGCCTGGGTCGGGGCAGCCCAGAACCCTCGGCCTTGCCTCCCCAGCGCATCCCCAGCGACATGGCCAGTCCTGAGCCCGA
GGGCTCTCAGAACAGCCTTCAGGCAGCCCCCGCAACCACCTCCTCCTGGGAGCCCCGGCGGGCAAGCACGGCCTTCTGCCCACCCGCTGC
CAGTTCCGAGGCACCTGACGGCCCCAGCAGCACTGCCCGCCTTGACTTCAAGGTCTCTGGCTTCTTCCTCTTCGGCTCCCCACTGGGCCT
GGTGCTGGCTCTGCGCAAAACTGTGATGCCCGCCCTGGAGGCAGCCCAGATGCGCCCAGCCTGTGAACAGATCTACAACCTCTTCCACGC
GGCTGACCCCTGCGCCTCACGCCTCGAGCCCCTGCTGGCCCCGAAGTTCCAGGCCATCGCCCCACTGACCGTGCCCCGCTACCAGAAGTT
CCCCCTGGGAGATGGCTCATCCCTGCTGCTGGCCGACACTCTGCAGACGCACTCCAGCCTCTTTCTGGAGGAGCTGGAGATGCTGGTGCC
CTCAACACCCACCTCTACTAGCGGTGCCTTCTGGAAGGGCAGTGAGTTGGCCACTGACCCCCCGGCCCAGCCAGCCGCCCCCAGCACCAC
CAGTGAGGTGGTTAAGATCCTGGAGCGCTGGTGGGGGACCAAGCGGATCGACTACTCGCTGTACTGCCCCGAGGCGCTCACCGCCTTTCC
CACCGTCACGCTGCCCCACCTCTTCCACGCCAGCTACTGGGAGTCCGCCGACGTGGTGGCGTTCATCCTGCGCCAGGTGATCGAGAAGGA
GCGGCCACAGCTGGCGGAATGCGAGGAGCCGTCCATCTACAGCCCGGCCTTCCCCAGGGAGAAGTGGCAGCGAAAACGCACGCAGGTCAA
GATCCGGAACGTCACTTCCAACCACCGGGCGAGCGACACGGTGGTGTGCGAGGGCCGCCCCCAGGTGCTAAGCGGGCGCTTCATGTACGG
GCCCCTGGACGTCGTCACGCTCACTGGAGAGAAGGTGGATGTCTACATCATGACGCAGCCGCTGTCGGGCAAGTGGATCCACTTTGGCAC
CGAAGTCACCAATAGCTCGGGCCGCCTCACCTTCCCAGTTCCCCCAGAACGCGCGCTGGGCATTGGTGTCTACCCCGTGCGCATGGTGGT
CAGGGGCGACCACACCTATGCCGAATGCTGCCTGACTGTGGTGGCCCGCGGCACGGAGGCTGTGGTCTTCAGCATCGACGGCTCCTTCAC
CGCCAGCGTCTCCATCATGGGCAGCGACCCCAAGGTGCGAGCTGGCGCCGTGGACGTGGTCAGGCACTGGCAGGACTCCGGCTACCTGAT
CGTGTATGTCACAGGCCGGCCGGATATGCAGAAGCACCGCGTGGTGGCATGGCTGTCGCAGCACAACTTCCCCCACGGCGTCGTCTCCTT
CTGCGACGGCCTCACCCACGACCCACTACGCCAGAAGGCAATGTTTCTGCAGAGCCTGGTGCAGGAGGTAGAACTGAACATCGTGGCCGG
TTATGGGTCTCCCAAAGATGTGGCTGTATACGCGGCGCTGGGGCTGTCCCCGAGCCAGACCTACATCGTGGGCCGTGCCGTGCGGAAGCT
ACAGGCGCAGTGCCAGTTCCTGTCAGACGGCTATGTGGCCCACCTGGGCCAGCTGGAAGCGGGCTCGCACTCGCATGCCTCCTCGGGACC
CCCGAGAGCTGCCTTGGGCAAGAGCAGCTATGGTGTGGCTGCCCCCGTGGACTTCCTGCGCAAACAGAGCCAGCTGCTTCGCTCGAGGGG
CCCCAGCCAGGCGGAGCGTGAGGGCCCGGGAACACCACCCACCACCCTGGCACGGGGCAAAGCACGGAGCATCAGCCTGAAGCTGGACAG
CGAGGAGTGAGGCCCACACCAGCCTGGACCTGGGTTATTTATTGACACACCCAAGGGGCCCGAGGGGCTGCGTGTGGGAGGCTGGGGACC
CAGACTTTTGGCCCCAGCGCTGGCCCCCCCAGCCCCACACCCTATATCTCCGTGTGCTCCTCGGTGTTACTTCCCTTTCATATGAGGGGA
CCCAGCGCCGGGGGGAGGGAGGAGGGCGTGGGCATGGGCGCAGAGGCTTTTCCAGTGTGTATAAATCCATGAAAATAAACGCCACCTGCA

>In-frame_ENST00000358965_ENST00000356404_TCGA-E2-A107-01A_NUMA1_chr11_71718235_-_PITPNM1_chr11_67265793_length(amino acids)=1868AA_start in transcript=240_stop in transcript=5846
MSGITKMTLHATRGAALLSWVNSLHVADPVEAVLQLQDCSIFIKIIDRIHGTEEGQQILKQPVSERLDFVCSFLQKNRKHPSSPECLVSA
QKVLEGSELELAKMTMLLLYHSTMSSKSPRDWEQFEYKIQAELAVILKFVLDHEDGLNLNEDLENFLQKAPVPSTCSSTFPEELSPPSHQ
AKREIRFLELQKVASSSSGNNFLSGSPASPMGDILQTPQFQMRRLKKQLADERSNRDELELELAENRKLLTEKDAQIAMMQQRIDRLALL
NEKQAASPLEPKELEELRDKNESLTMRLHETLKQCQDLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEHSKATQE
WLEKQAQLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVEMLETERG
QQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQ
LAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQL
QVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVT
KGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLGEAHQAETEVLRRELAEAMAAQHTAESECE
QLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKEECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVR
AQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDRQPEWLEEQQGRQFCSTQAALQAMEREAEQMGNELERL
RAALMESQGQQQEERGQQEREVARLTQERGRAQADLALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEA
AQIKELEELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQEQADSLERSLEAERASRAERDSAL
ETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRL
VMAESEKSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAERAEELGQELKAWQEKFFQKEQALS
TLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKASYA
EQLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQ
RFQEERQKLTAQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQN
QELQEQLRSLEQLQKENKELRAEAERLGHELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLGKFQVATDALKSREPQAKPQL
DLSIDSLDLSCEEGTPLSITSKLPRTQPDGTSVPGEPASPISQRLPPKVESLESLYFTPIPARSQAPLESSLDSLGDVFLDSGRKTRSAR

--------------------------------------------------------------
>In-frame_ENST00000358965_ENST00000534749_TCGA-E2-A107_NUMA1_chr11_71718234_-_PITPNM1_chr11_67265793_length(transcript)=8195nt_BP=5679nt
GCCCACGAAGAGGTACGATTCCGGAGAATCGCGAGGCAGAGCGGGAGCGCGCAGCCAGGTGGAAACTAATTCTAAGCCAGACTGCTGGAG
ATCACCCTGTTCTAGTGTGTGGAGGCTTCCACCAGGAGTCTGGAGTGCAATGGCACGATCTCGGCTCACTGCAACCTCCACCTCCCAGGT
TCAAGCGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGCGCATTGGAGTGACTGTCTGGCATCACCAAGATGACACTCCAC
GCCACCCGGGGGGCTGCACTCCTCTCTTGGGTGAACAGTCTACACGTGGCTGACCCTGTGGAGGCTGTGCTGCAGCTCCAGGACTGCAGC
ATCTTCATCAAGATCATTGACAGAATCCATGGCACTGAAGAGGGACAGCAAATCTTGAAGCAGCCGGTGTCAGAGAGACTGGACTTTGTG
TGCAGTTTTCTGCAGAAAAATCGAAAACATCCCTCTTCCCCAGAATGCCTGGTATCTGCACAGAAGGTGCTAGAGGGATCAGAGCTGGAA
CTGGCGAAGATGACCATGCTGCTCTTATACCACTCTACCATGAGCTCCAAAAGTCCCAGGGACTGGGAACAGTTTGAATATAAAATTCAG
GCTGAGTTGGCTGTCATTCTTAAATTTGTGCTGGACCATGAGGACGGGCTAAACCTTAATGAGGACCTAGAGAACTTCCTACAGAAAGCT
CCTGTGCCTTCTACCTGTTCTAGCACATTCCCTGAAGAGCTCTCCCCACCTAGCCACCAGGCCAAGAGGGAGATTCGCTTCCTAGAGCTA
CAGAAGGTTGCCTCCTCTTCCAGTGGGAACAACTTTCTCTCAGGTTCTCCAGCTTCTCCCATGGGTGATATCCTGCAGACCCCACAGTTC
CAGATGAGACGGCTGAAGAAGCAGCTTGCTGATGAGAGAAGTAATAGGGATGAGCTGGAGCTGGAGCTAGCTGAGAACCGCAAGCTCCTC
ACCGAGAAGGATGCACAGATAGCCATGATGCAGCAGCGCATTGACCGCCTAGCCCTGCTGAATGAGAAGCAGGCGGCCAGCCCACTGGAG
CCCAAGGAGCTTGAGGAGCTGCGTGACAAGAATGAGAGCCTTACCATGCGGCTGCATGAAACCCTGAAGCAGTGCCAGGACCTGAAGACA
GAGAAGAGCCAGATGGATCGCAAAATCAACCAGCTTTCGGAGGAGAATGGAGACCTTTCCTTTAAGCTGCGGGAGTTTGCCAGTCATCTG
CAGCAGCTACAGGATGCCCTCAATGAGCTGACGGAGGAGCACAGCAAGGCCACTCAGGAGTGGCTAGAGAAGCAGGCCCAGCTGGAGAAG
GAGCTCAGCGCAGCCCTGCAGGACAAGAAATGCCTTGAAGAGAAGAACGAAATCCTTCAGGGAAAACTTTCACAGCTGGAAGAACACTTG
TCCCAGCTGCAGGATAACCCACCCCAGGAGAAGGGCGAGGTGCTGGGTGATGTCTTGCAGCTGGAAACCTTGAAGCAAGAGGCAGCCACT
CTTGCTGCAAACAACACACAGCTCCAAGCCAGGGTAGAGATGCTGGAGACTGAGCGAGGCCAGCAGGAAGCCAAGCTGCTTGCTGAGCGG
GGCCACTTCGAAGAAGAAAAGCAGCAGCTGTCTAGCCTGATCACTGACCTGCAGAGCTCCATCTCCAACCTCAGCCAGGCCAAGGAAGAG
CTGGAGCAGGCCTCCCAGGCTCATGGGGCCCGGTTGACTGCCCAGGTGGCCTCTCTGACCTCTGAGCTCACCACACTCAATGCCACCATC
CAGCAACAGGATCAAGAACTGGCTGGCCTGAAGCAGCAGGCCAAAGAGAAGCAGGCCCAGCTAGCACAGACCCTCCAACAGCAAGAACAG
GCCTCCCAGGGCCTCCGCCACCAGGTGGAGCAGCTAAGCAGTAGCCTGAAGCAGAAGGAGCAGCAGTTGAAGGAGGTAGCGGAGAAGCAG
GAGGCAACTAGGCAGGACCATGCCCAGCAACTGGCCACTGCTGCAGAGGAGCGAGAGGCCTCCTTAAGGGAGCGGGATGCGGCTCTCAAG
CAGCTGGAGGCACTGGAGAAGGAGAAGGCTGCCAAGCTGGAGATTCTGCAGCAGCAACTTCAGGTGGCTAATGAAGCCCGGGACAGTGCC
CAGACCTCAGTGACACAGGCCCAGCGGGAGAAGGCAGAGCTGAGCCGGAAGGTGGAGGAACTCCAGGCCTGTGTTGAGACAGCCCGCCAG
GAACAGCATGAGGCCCAGGCCCAGGTTGCAGAGCTAGAGTTGCAGCTGCGGTCTGAGCAGCAAAAAGCAACTGAGAAAGAAAGGGTGGCC
CAGGAGAAGGACCAGCTCCAGGAGCAGCTCCAGGCCCTCAAAGAGTCCTTGAAGGTCACCAAGGGCAGCCTTGAAGAGGAGAAGCGCAGG
GCTGCAGATGCCCTGGAAGAGCAGCAGCGTTGTATCTCTGAGCTGAAGGCAGAGACCCGAAGCCTGGTGGAGCAGCATAAGCGGGAACGA
AAGGAGCTGGAAGAAGAGAGGGCTGGGCGCAAGGGGCTGGAGGCTCGATTACAGCAGCTTGGGGAGGCCCATCAGGCTGAGACTGAAGTC
CTGCGGCGGGAGCTGGCAGAGGCCATGGCTGCCCAGCACACAGCTGAGAGTGAGTGTGAGCAGCTCGTCAAAGAAGTAGCTGCCTGGCGT
GAGCGGTATGAGGATAGCCAGCAAGAGGAGGCACAGTATGGCGCCATGTTCCAGGAACAGCTGATGACTTTGAAGGAGGAATGTGAGAAG
GCCCGCCAGGAGCTGCAGGAGGCAAAGGAGAAGGTGGCAGGCATAGAATCCCACAGCGAGCTCCAGATAAGCCGGCAGCAGAACGAACTA
GCTGAGCTCCATGCCAACCTGGCCAGAGCACTCCAGCAGGTCCAAGAGAAGGAAGTCAGGGCCCAGAAGCTTGCAGATGACCTCTCCACT
CTGCAGGAAAAGATGGCTGCCACCAGCAAAGAGGTGGCCCGCTTGGAGACCTTGGTGCGCAAGGCAGGTGAGCAGCAGGAAACAGCCTCC
CGGGAGTTAGTCAAGGAGCCTGCGAGGGCAGGAGACAGACAGCCCGAGTGGCTGGAAGAGCAACAGGGACGCCAGTTCTGCAGCACACAG
GCAGCGCTGCAGGCTATGGAGCGGGAGGCAGAGCAGATGGGCAATGAGCTGGAACGGCTGCGGGCCGCGCTGATGGAGAGCCAGGGGCAG
CAGCAGGAGGAGCGTGGGCAGCAGGAAAGGGAGGTGGCGCGGCTGACCCAGGAGCGGGGCCGTGCCCAGGCTGACCTTGCCCTGGAGAAG
GCGGCCAGAGCAGAGCTTGAGATGCGGCTGCAGAACGCCCTCAACGAGCAGCGTGTGGAGTTCGCTACCCTGCAAGAGGCACTGGCTCAT
GCCCTGACGGAAAAGGAAGGCAAGGACCAGGAGTTGGCCAAGCTTCGTGGTCTGGAGGCAGCCCAGATAAAAGAGCTGGAGGAACTTCGG
CAAACCGTGAAGCAACTGAAGGAACAGCTGGCTAAGAAAGAAAAGGAGCACGCATCTGGCTCAGGAGCCCAATCTGAGGCTGCTGGCAGG
ACAGAGCCAACAGGCCCCAAGCTGGAGGCACTGCGGGCAGAGGTGAGCAAGCTGGAACAGCAATGCCAGAAGCAGCAGGAGCAGGCTGAC
AGCCTGGAACGCAGCCTCGAGGCTGAGCGGGCCTCCCGGGCTGAGCGGGACAGTGCTCTGGAGACTCTGCAGGGCCAGTTAGAGGAGAAG
GCCCAGGAGCTAGGGCACAGTCAGAGTGCCTTAGCCTCGGCCCAACGGGAGTTGGCTGCCTTCCGCACCAAGGTACAAGACCACAGCAAG
GCTGAAGATGAGTGGAAGGCCCAGGTGGCCCGGGGCCGGCAAGAGGCTGAGAGGAAAAATAGCCTCATCAGCAGCTTGGAGGAGGAGGTG
TCCATCCTGAATCGCCAGGTCCTGGAGAAGGAGGGGGAGAGCAAGGAGTTGAAGCGGCTGGTGATGGCCGAGTCAGAGAAGAGCCAGAAG
CTGGAGGAGAGGCTGCGCCTGCTGCAGGCAGAGACAGCCAGCAACAGTGCCAGAGCTGCAGAACGCAGCTCTGCTCTGCGGGAGGAGGTG
CAGAGCCTCCGGGAGGAGGCTGAGAAACAGCGGGTGGCTTCAGAGAACCTGCGGCAGGAGCTGACCTCACAGGCTGAGCGTGCGGAGGAG
CTGGGCCAAGAATTGAAGGCGTGGCAGGAGAAGTTCTTCCAGAAAGAGCAGGCCCTCTCCACCCTGCAGCTCGAGCACACCAGCACACAG
GCCCTGGTGAGTGAGCTGCTGCCAGCTAAGCACCTCTGCCAGCAGCTGCAGGCCGAGCAGGCCGCTGCCGAGAAACGCCACCGTGAGGAG
CTGGAGCAGAGCAAGCAGGCCGCTGGGGGACTGCGGGCAGAGCTGCTGCGGGCCCAGCGGGAGCTTGGGGAGCTGATTCCTCTGCGGCAG
AAGGTGGCAGAGCAGGAGCGAACAGCTCAGCAGCTGCGGGCAGAGAAGGCCAGCTATGCAGAGCAGCTGAGCATGCTGAAGAAGGCGCAT
GGCCTGCTGGCAGAGGAGAACCGGGGGCTGGGTGAGCGGGCCAACCTTGGCCGGCAGTTTCTGGAAGTGGAGTTGGACCAGGCCCGGGAG
AAGTATGTCCAAGAGTTGGCAGCCGTACGTGCTGATGCTGAGACCCGTCTGGCTGAGGTGCAGCGAGAAGCACAGAGCACTGCCCGGGAG
CTGGAGGTGATGACTGCCAAGTATGAGGGTGCCAAGGTCAAGGTCCTGGAGGAGAGGCAGCGGTTCCAGGAAGAGAGGCAGAAACTCACT
GCCCAGGTGGAAGAACTGAGTAAGAAACTGGCTGACTCTGACCAAGCCAGCAAGGTGCAGCAGCAGAAGCTGAAGGCTGTCCAGGCTCAG
GGAGGCGAGAGCCAGCAGGAGGCCCAGCGCCTCCAGGCCCAGCTGAATGAACTGCAAGCCCAGTTGAGCCAGAAGGAGCAGGCAGCTGAG
CACTATAAGCTGCAGATGGAGAAAGCCAAAACACATTATGATGCCAAGAAGCAGCAGAACCAAGAGCTGCAGGAGCAGCTGCGGAGCCTG
GAGCAGCTGCAGAAGGAAAACAAAGAGCTGCGAGCTGAAGCTGAACGGCTGGGCCATGAGCTACAGCAGGCTGGGCTGAAGACCAAGGAG
GCTGAACAGACCTGCCGCCACCTTACTGCCCAGGTGCGCAGCCTGGAGGCACAGGTTGCCCATGCAGACCAGCAGCTTCGAGACCTGGGC
AAATTCCAGGTGGCAACTGATGCTTTAAAGAGCCGTGAGCCCCAGGCTAAGCCCCAGCTGGACTTGAGTATTGACAGCCTGGATCTGAGC
TGCGAGGAGGGGACCCCACTCAGTATCACCAGCAAGCTGCCTCGTACCCAGCCAGACGGCACCAGCGTCCCTGGAGAACCAGCCTCACCT
ATCTCCCAGCGCCTGCCCCCCAAGGTAGAATCCCTGGAGAGTCTCTACTTCACTCCCATCCCTGCTCGGAGTCAGGCCCCCCTGGAGAGC
AGCCTGGACTCCCTGGGAGACGTCTTCCTGGACTCGGGTCGTAAGACCCGCTCCGCTCGTCGGCGCACCACGCAGATCATCAACATCACC
ATGACCAAGCCTGAGCCCTTACAGCCACGATGGGGACAGCCTGTCTCGCTCCCAAGACCACATTCCACTGGCTGCCCTGCCACTGCTGGC
CACCTCATCCTCCCGCTACCAGGGCGCCGTGGCCACCGTCATTGCCCGCACCAACCAGGCCTACTCAGCCTTCCTGCGCTCACCTGAGGG
TGCCGGCTTCTGTGGGCAGGTCGCACTGATTGGAGATGGTGTTGGTGGCATCCTGGGCTTTGATGCACTCTGCCACAGTGCTAACGCGGG
CACCGGGAGTCGGGGCAGCAGCCGCCGTGGGAGCATGAACAATGAGCTGCTCTCTCCGGAGTTTGGCCCAGTGCGGGACCCCCTGGCAGA
TGGTGTGGAAGGCCTGGGTCGGGGCAGCCCAGAACCCTCGGCCTTGCCTCCCCAGCGCATCCCCAGCGACATGGCCAGTCCTGAGCCCGA
GGGCTCTCAGAACAGCCTTCAGGCAGCCCCCGCAACCACCTCCTCCTGGGAGCCCCGGCGGGCAAGCACGGCCTTCTGCCCACCCGCTGC
CAGTTCCGAGGCACCTGACGGCCCCAGCAGCACTGCCCGCCTTGACTTCAAGGTCTCTGGCTTCTTCCTCTTCGGCTCCCCACTGGGCCT
GGTGCTGGCTCTGCGCAAAACTGTGATGCCCGCCCTGGAGGCAGCCCAGATGCGCCCAGCCTGTGAACAGATCTACAACCTCTTCCACGC
GGCTGACCCCTGCGCCTCACGCCTCGAGCCCCTGCTGGCCCCGAAGTTCCAGGCCATCGCCCCACTGACCGTGCCCCGCTACCAGAAGTT
CCCCCTGGGAGATGGCTCATCCCTGCTGCTGGCCGACACTCTGCAGACGCACTCCAGCCTCTTTCTGGAGGAGCTGGAGATGCTGGTGCC
CTCAACACCCACCTCTACTAGCGGTGCCTTCTGGAAGGGCAGTGAGTTGGCCACTGACCCCCCGGCCCAGCCAGCCGCCCCCAGCACCAC
CAGTGAGGTGGTTAAGATCCTGGAGCGCTGGTGGGGGACCAAGCGGATCGACTACTCGCTGTACTGCCCCGAGGCGCTCACCGCCTTTCC
CACCGTCACGCTGCCCCACCTCTTCCACGCCAGCTACTGGGAGTCCGCCGACGTGGTGGCGTTCATCCTGCGCCAGGTGATCGAGAAGGA
GCGGCCACAGCTGGCGGAATGCGAGGAGCCGTCCATCTACAGCCCGGCCTTCCCCAGGGAGAAGTGGCAGCGAAAACGCACGCAGGTCAA
GATCCGGAACGTCACTTCCAACCACCGGGCGAGCGACACGGTGGTGTGCGAGGGCCGCCCCCAGGTGCTAAGCGGGCGCTTCATGTACGG
GCCCCTGGACGTCGTCACGCTCACTGGAGAGAAGGTGGATGTCTACATCATGACGCAGCCGCTGTCGGGCAAGTGGATCCACTTTGGCAC
CGAAGTCACCAATAGCTCGGGCCGCCTCACCTTCCCAGTTCCCCCAGAACGCGCGCTGGGCATTGGTGTCTACCCCGTGCGCATGGTGGT
CAGGGGCGACCACACCTATGCCGAATGCTGCCTGACTGTGGTGGCCCGCGGCACGGAGGCTGTGGTCTTCAGCATCGACGGCTCCTTCAC
CGCCAGCGTCTCCATCATGGGCAGCGACCCCAAGGTGCGAGCTGGCGCCGTGGACGTGGTCAGGCACTGGCAGGACTCCGGCTACCTGAT
CGTGTATGTCACAGGCCGGCCGGATATGCAGAAGCACCGCGTGGTGGCATGGCTGTCGCAGCACAACTTCCCCCACGGCGTCGTCTCCTT
CTGCGACGGCCTCACCCACGACCCACTACGCCAGAAGGCAATGTTTCTGCAGAGCCTGGTGCAGGAGGTAGAACTGAACATCGTGGCCGG
TTATGGGTCTCCCAAAGATGTGGCTGTATACGCGGCGCTGGGGCTGTCCCCGAGCCAGACCTACATCGTGGGCCGTGCCGTGCGGAAGCT
ACAGGCGCAGTGCCAGTTCCTGTCAGACGGCTATGTGGCCCACCTGGGCCAGCTGGAAGCGGGCTCGCACTCGCATGCCTCCTCGGGACC
CCCGAGAGCTGCCTTGGGCAAGAGCAGCTATGGTGTGGCTGCCCCCGTGGACTTCCTGCGCAAACAGAGCCAGCTGCTTCGCTCGAGGGG
CCCCAGCCAGGCGGAGCGTGAGGGCCCGGGAACACCACCCACCACCCTGGCACGGGGCAAAGCACGGAGCATCAGCCTGAAGCTGGACAG
CGAGGAGTGAGGCCCACACCAGCCTGGACCTGGGTTATTTATTGACACACCCAAGGGGCCCGAGGGGCTGCGTGTGGGAGGCTGGGGACC
CAGACTTTTGGCCCCAGCGCTGGCCCCCCCAGCCCCACACCCTATATCTCCGTGTGCTCCTCGGTGTTACTTCCCTTTCATATGAGGGGA
CCCAGCGCCGGGGGGAGGGAGGAGGGCGTGGGCATGGGCGCAGAGGCTTTTCCAGTGTGTATAAATCCATGAAAATAAACGCCACCTGCA

>In-frame_ENST00000358965_ENST00000534749_TCGA-E2-A107_NUMA1_chr11_71718234_-_PITPNM1_chr11_67265793_length(amino acids)=1868AA_start in transcript=240_stop in transcript=5846
MSGITKMTLHATRGAALLSWVNSLHVADPVEAVLQLQDCSIFIKIIDRIHGTEEGQQILKQPVSERLDFVCSFLQKNRKHPSSPECLVSA
QKVLEGSELELAKMTMLLLYHSTMSSKSPRDWEQFEYKIQAELAVILKFVLDHEDGLNLNEDLENFLQKAPVPSTCSSTFPEELSPPSHQ
AKREIRFLELQKVASSSSGNNFLSGSPASPMGDILQTPQFQMRRLKKQLADERSNRDELELELAENRKLLTEKDAQIAMMQQRIDRLALL
NEKQAASPLEPKELEELRDKNESLTMRLHETLKQCQDLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEHSKATQE
WLEKQAQLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVEMLETERG
QQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQ
LAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQL
QVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVT
KGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLGEAHQAETEVLRRELAEAMAAQHTAESECE
QLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKEECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVR
AQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDRQPEWLEEQQGRQFCSTQAALQAMEREAEQMGNELERL
RAALMESQGQQQEERGQQEREVARLTQERGRAQADLALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEA
AQIKELEELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQEQADSLERSLEAERASRAERDSAL
ETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRL
VMAESEKSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAERAEELGQELKAWQEKFFQKEQALS
TLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKASYA
EQLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQ
RFQEERQKLTAQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQN
QELQEQLRSLEQLQKENKELRAEAERLGHELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLGKFQVATDALKSREPQAKPQL
DLSIDSLDLSCEEGTPLSITSKLPRTQPDGTSVPGEPASPISQRLPPKVESLESLYFTPIPARSQAPLESSLDSLGDVFLDSGRKTRSAR

--------------------------------------------------------------
>In-frame_ENST00000358965_ENST00000436757_TCGA-E2-A107_NUMA1_chr11_71718234_-_PITPNM1_chr11_67265793_length(transcript)=8192nt_BP=5679nt
GCCCACGAAGAGGTACGATTCCGGAGAATCGCGAGGCAGAGCGGGAGCGCGCAGCCAGGTGGAAACTAATTCTAAGCCAGACTGCTGGAG
ATCACCCTGTTCTAGTGTGTGGAGGCTTCCACCAGGAGTCTGGAGTGCAATGGCACGATCTCGGCTCACTGCAACCTCCACCTCCCAGGT
TCAAGCGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGCGCATTGGAGTGACTGTCTGGCATCACCAAGATGACACTCCAC
GCCACCCGGGGGGCTGCACTCCTCTCTTGGGTGAACAGTCTACACGTGGCTGACCCTGTGGAGGCTGTGCTGCAGCTCCAGGACTGCAGC
ATCTTCATCAAGATCATTGACAGAATCCATGGCACTGAAGAGGGACAGCAAATCTTGAAGCAGCCGGTGTCAGAGAGACTGGACTTTGTG
TGCAGTTTTCTGCAGAAAAATCGAAAACATCCCTCTTCCCCAGAATGCCTGGTATCTGCACAGAAGGTGCTAGAGGGATCAGAGCTGGAA
CTGGCGAAGATGACCATGCTGCTCTTATACCACTCTACCATGAGCTCCAAAAGTCCCAGGGACTGGGAACAGTTTGAATATAAAATTCAG
GCTGAGTTGGCTGTCATTCTTAAATTTGTGCTGGACCATGAGGACGGGCTAAACCTTAATGAGGACCTAGAGAACTTCCTACAGAAAGCT
CCTGTGCCTTCTACCTGTTCTAGCACATTCCCTGAAGAGCTCTCCCCACCTAGCCACCAGGCCAAGAGGGAGATTCGCTTCCTAGAGCTA
CAGAAGGTTGCCTCCTCTTCCAGTGGGAACAACTTTCTCTCAGGTTCTCCAGCTTCTCCCATGGGTGATATCCTGCAGACCCCACAGTTC
CAGATGAGACGGCTGAAGAAGCAGCTTGCTGATGAGAGAAGTAATAGGGATGAGCTGGAGCTGGAGCTAGCTGAGAACCGCAAGCTCCTC
ACCGAGAAGGATGCACAGATAGCCATGATGCAGCAGCGCATTGACCGCCTAGCCCTGCTGAATGAGAAGCAGGCGGCCAGCCCACTGGAG
CCCAAGGAGCTTGAGGAGCTGCGTGACAAGAATGAGAGCCTTACCATGCGGCTGCATGAAACCCTGAAGCAGTGCCAGGACCTGAAGACA
GAGAAGAGCCAGATGGATCGCAAAATCAACCAGCTTTCGGAGGAGAATGGAGACCTTTCCTTTAAGCTGCGGGAGTTTGCCAGTCATCTG
CAGCAGCTACAGGATGCCCTCAATGAGCTGACGGAGGAGCACAGCAAGGCCACTCAGGAGTGGCTAGAGAAGCAGGCCCAGCTGGAGAAG
GAGCTCAGCGCAGCCCTGCAGGACAAGAAATGCCTTGAAGAGAAGAACGAAATCCTTCAGGGAAAACTTTCACAGCTGGAAGAACACTTG
TCCCAGCTGCAGGATAACCCACCCCAGGAGAAGGGCGAGGTGCTGGGTGATGTCTTGCAGCTGGAAACCTTGAAGCAAGAGGCAGCCACT
CTTGCTGCAAACAACACACAGCTCCAAGCCAGGGTAGAGATGCTGGAGACTGAGCGAGGCCAGCAGGAAGCCAAGCTGCTTGCTGAGCGG
GGCCACTTCGAAGAAGAAAAGCAGCAGCTGTCTAGCCTGATCACTGACCTGCAGAGCTCCATCTCCAACCTCAGCCAGGCCAAGGAAGAG
CTGGAGCAGGCCTCCCAGGCTCATGGGGCCCGGTTGACTGCCCAGGTGGCCTCTCTGACCTCTGAGCTCACCACACTCAATGCCACCATC
CAGCAACAGGATCAAGAACTGGCTGGCCTGAAGCAGCAGGCCAAAGAGAAGCAGGCCCAGCTAGCACAGACCCTCCAACAGCAAGAACAG
GCCTCCCAGGGCCTCCGCCACCAGGTGGAGCAGCTAAGCAGTAGCCTGAAGCAGAAGGAGCAGCAGTTGAAGGAGGTAGCGGAGAAGCAG
GAGGCAACTAGGCAGGACCATGCCCAGCAACTGGCCACTGCTGCAGAGGAGCGAGAGGCCTCCTTAAGGGAGCGGGATGCGGCTCTCAAG
CAGCTGGAGGCACTGGAGAAGGAGAAGGCTGCCAAGCTGGAGATTCTGCAGCAGCAACTTCAGGTGGCTAATGAAGCCCGGGACAGTGCC
CAGACCTCAGTGACACAGGCCCAGCGGGAGAAGGCAGAGCTGAGCCGGAAGGTGGAGGAACTCCAGGCCTGTGTTGAGACAGCCCGCCAG
GAACAGCATGAGGCCCAGGCCCAGGTTGCAGAGCTAGAGTTGCAGCTGCGGTCTGAGCAGCAAAAAGCAACTGAGAAAGAAAGGGTGGCC
CAGGAGAAGGACCAGCTCCAGGAGCAGCTCCAGGCCCTCAAAGAGTCCTTGAAGGTCACCAAGGGCAGCCTTGAAGAGGAGAAGCGCAGG
GCTGCAGATGCCCTGGAAGAGCAGCAGCGTTGTATCTCTGAGCTGAAGGCAGAGACCCGAAGCCTGGTGGAGCAGCATAAGCGGGAACGA
AAGGAGCTGGAAGAAGAGAGGGCTGGGCGCAAGGGGCTGGAGGCTCGATTACAGCAGCTTGGGGAGGCCCATCAGGCTGAGACTGAAGTC
CTGCGGCGGGAGCTGGCAGAGGCCATGGCTGCCCAGCACACAGCTGAGAGTGAGTGTGAGCAGCTCGTCAAAGAAGTAGCTGCCTGGCGT
GAGCGGTATGAGGATAGCCAGCAAGAGGAGGCACAGTATGGCGCCATGTTCCAGGAACAGCTGATGACTTTGAAGGAGGAATGTGAGAAG
GCCCGCCAGGAGCTGCAGGAGGCAAAGGAGAAGGTGGCAGGCATAGAATCCCACAGCGAGCTCCAGATAAGCCGGCAGCAGAACGAACTA
GCTGAGCTCCATGCCAACCTGGCCAGAGCACTCCAGCAGGTCCAAGAGAAGGAAGTCAGGGCCCAGAAGCTTGCAGATGACCTCTCCACT
CTGCAGGAAAAGATGGCTGCCACCAGCAAAGAGGTGGCCCGCTTGGAGACCTTGGTGCGCAAGGCAGGTGAGCAGCAGGAAACAGCCTCC
CGGGAGTTAGTCAAGGAGCCTGCGAGGGCAGGAGACAGACAGCCCGAGTGGCTGGAAGAGCAACAGGGACGCCAGTTCTGCAGCACACAG
GCAGCGCTGCAGGCTATGGAGCGGGAGGCAGAGCAGATGGGCAATGAGCTGGAACGGCTGCGGGCCGCGCTGATGGAGAGCCAGGGGCAG
CAGCAGGAGGAGCGTGGGCAGCAGGAAAGGGAGGTGGCGCGGCTGACCCAGGAGCGGGGCCGTGCCCAGGCTGACCTTGCCCTGGAGAAG
GCGGCCAGAGCAGAGCTTGAGATGCGGCTGCAGAACGCCCTCAACGAGCAGCGTGTGGAGTTCGCTACCCTGCAAGAGGCACTGGCTCAT
GCCCTGACGGAAAAGGAAGGCAAGGACCAGGAGTTGGCCAAGCTTCGTGGTCTGGAGGCAGCCCAGATAAAAGAGCTGGAGGAACTTCGG
CAAACCGTGAAGCAACTGAAGGAACAGCTGGCTAAGAAAGAAAAGGAGCACGCATCTGGCTCAGGAGCCCAATCTGAGGCTGCTGGCAGG
ACAGAGCCAACAGGCCCCAAGCTGGAGGCACTGCGGGCAGAGGTGAGCAAGCTGGAACAGCAATGCCAGAAGCAGCAGGAGCAGGCTGAC
AGCCTGGAACGCAGCCTCGAGGCTGAGCGGGCCTCCCGGGCTGAGCGGGACAGTGCTCTGGAGACTCTGCAGGGCCAGTTAGAGGAGAAG
GCCCAGGAGCTAGGGCACAGTCAGAGTGCCTTAGCCTCGGCCCAACGGGAGTTGGCTGCCTTCCGCACCAAGGTACAAGACCACAGCAAG
GCTGAAGATGAGTGGAAGGCCCAGGTGGCCCGGGGCCGGCAAGAGGCTGAGAGGAAAAATAGCCTCATCAGCAGCTTGGAGGAGGAGGTG
TCCATCCTGAATCGCCAGGTCCTGGAGAAGGAGGGGGAGAGCAAGGAGTTGAAGCGGCTGGTGATGGCCGAGTCAGAGAAGAGCCAGAAG
CTGGAGGAGAGGCTGCGCCTGCTGCAGGCAGAGACAGCCAGCAACAGTGCCAGAGCTGCAGAACGCAGCTCTGCTCTGCGGGAGGAGGTG
CAGAGCCTCCGGGAGGAGGCTGAGAAACAGCGGGTGGCTTCAGAGAACCTGCGGCAGGAGCTGACCTCACAGGCTGAGCGTGCGGAGGAG
CTGGGCCAAGAATTGAAGGCGTGGCAGGAGAAGTTCTTCCAGAAAGAGCAGGCCCTCTCCACCCTGCAGCTCGAGCACACCAGCACACAG
GCCCTGGTGAGTGAGCTGCTGCCAGCTAAGCACCTCTGCCAGCAGCTGCAGGCCGAGCAGGCCGCTGCCGAGAAACGCCACCGTGAGGAG
CTGGAGCAGAGCAAGCAGGCCGCTGGGGGACTGCGGGCAGAGCTGCTGCGGGCCCAGCGGGAGCTTGGGGAGCTGATTCCTCTGCGGCAG
AAGGTGGCAGAGCAGGAGCGAACAGCTCAGCAGCTGCGGGCAGAGAAGGCCAGCTATGCAGAGCAGCTGAGCATGCTGAAGAAGGCGCAT
GGCCTGCTGGCAGAGGAGAACCGGGGGCTGGGTGAGCGGGCCAACCTTGGCCGGCAGTTTCTGGAAGTGGAGTTGGACCAGGCCCGGGAG
AAGTATGTCCAAGAGTTGGCAGCCGTACGTGCTGATGCTGAGACCCGTCTGGCTGAGGTGCAGCGAGAAGCACAGAGCACTGCCCGGGAG
CTGGAGGTGATGACTGCCAAGTATGAGGGTGCCAAGGTCAAGGTCCTGGAGGAGAGGCAGCGGTTCCAGGAAGAGAGGCAGAAACTCACT
GCCCAGGTGGAAGAACTGAGTAAGAAACTGGCTGACTCTGACCAAGCCAGCAAGGTGCAGCAGCAGAAGCTGAAGGCTGTCCAGGCTCAG
GGAGGCGAGAGCCAGCAGGAGGCCCAGCGCCTCCAGGCCCAGCTGAATGAACTGCAAGCCCAGTTGAGCCAGAAGGAGCAGGCAGCTGAG
CACTATAAGCTGCAGATGGAGAAAGCCAAAACACATTATGATGCCAAGAAGCAGCAGAACCAAGAGCTGCAGGAGCAGCTGCGGAGCCTG
GAGCAGCTGCAGAAGGAAAACAAAGAGCTGCGAGCTGAAGCTGAACGGCTGGGCCATGAGCTACAGCAGGCTGGGCTGAAGACCAAGGAG
GCTGAACAGACCTGCCGCCACCTTACTGCCCAGGTGCGCAGCCTGGAGGCACAGGTTGCCCATGCAGACCAGCAGCTTCGAGACCTGGGC
AAATTCCAGGTGGCAACTGATGCTTTAAAGAGCCGTGAGCCCCAGGCTAAGCCCCAGCTGGACTTGAGTATTGACAGCCTGGATCTGAGC
TGCGAGGAGGGGACCCCACTCAGTATCACCAGCAAGCTGCCTCGTACCCAGCCAGACGGCACCAGCGTCCCTGGAGAACCAGCCTCACCT
ATCTCCCAGCGCCTGCCCCCCAAGGTAGAATCCCTGGAGAGTCTCTACTTCACTCCCATCCCTGCTCGGAGTCAGGCCCCCCTGGAGAGC
AGCCTGGACTCCCTGGGAGACGTCTTCCTGGACTCGGGTCGTAAGACCCGCTCCGCTCGTCGGCGCACCACGCAGATCATCAACATCACC
ATGACCAAGCCTGAGCCCTTACAGCCACGATGGGGACAGCCTGTCTCGCTCCCAAGACCACATTCCACTGGCTGCCCTGCCACTGCTGGC
CACCTCATCCTCCCGCTACCAGGGCGCCGTGGCCACCGTCATTGCCCGCACCAACCAGGCCTACTCAGCCTTCCTGCGCTCACCTGAGGG
TGCCGGCTTCTGTGGGCAGGTCGCACTGATTGGAGATGGTGTTGGTGGCATCCTGGGCTTTGATGCACTCTGCCACAGTGCTAACGCGGG
CACCGGGAGTCGGGGCAGCAGCCGCCGTGGGAGCATGAACAATGAGCTGCTCTCTCCGGAGTTTGGCCCAGTGCGGGACCCCCTGGCAGA
TGGTGTGGAAGGCCTGGGTCGGGGCAGCCCAGAACCCTCGGCCTTGCCTCCCCAGCGCATCCCCAGCGACATGGCCAGTCCTGAGCCCGA
GGGCTCTCAGAACAGCCTTCAGGCAGCCCCCGCAACCACCTCCTCCTGGGAGCCCCGGCGGGCAAGCACGGCCTTCTGCCCACCCGCTGC
CAGTTCCGAGGCACCTGACGGCCCCAGCAGCACTGCCCGCCTTGACTTCAAGGTCTCTGGCTTCTTCCTCTTCGGCTCCCCACTGGGCCT
GGTGCTGGCTCTGCGCAAAACTGTGATGCCCGCCCTGGAGGCCCAGATGCGCCCAGCCTGTGAACAGATCTACAACCTCTTCCACGCGGC
TGACCCCTGCGCCTCACGCCTCGAGCCCCTGCTGGCCCCGAAGTTCCAGGCCATCGCCCCACTGACCGTGCCCCGCTACCAGAAGTTCCC
CCTGGGAGATGGCTCATCCCTGCTGCTGGCCGACACTCTGCAGACGCACTCCAGCCTCTTTCTGGAGGAGCTGGAGATGCTGGTGCCCTC
AACACCCACCTCTACTAGCGGTGCCTTCTGGAAGGGCAGTGAGTTGGCCACTGACCCCCCGGCCCAGCCAGCCGCCCCCAGCACCACCAG
TGAGGTGGTTAAGATCCTGGAGCGCTGGTGGGGGACCAAGCGGATCGACTACTCGCTGTACTGCCCCGAGGCGCTCACCGCCTTTCCCAC
CGTCACGCTGCCCCACCTCTTCCACGCCAGCTACTGGGAGTCCGCCGACGTGGTGGCGTTCATCCTGCGCCAGGTGATCGAGAAGGAGCG
GCCACAGCTGGCGGAATGCGAGGAGCCGTCCATCTACAGCCCGGCCTTCCCCAGGGAGAAGTGGCAGCGAAAACGCACGCAGGTCAAGAT
CCGGAACGTCACTTCCAACCACCGGGCGAGCGACACGGTGGTGTGCGAGGGCCGCCCCCAGGTGCTAAGCGGGCGCTTCATGTACGGGCC
CCTGGACGTCGTCACGCTCACTGGAGAGAAGGTGGATGTCTACATCATGACGCAGCCGCTGTCGGGCAAGTGGATCCACTTTGGCACCGA
AGTCACCAATAGCTCGGGCCGCCTCACCTTCCCAGTTCCCCCAGAACGCGCGCTGGGCATTGGTGTCTACCCCGTGCGCATGGTGGTCAG
GGGCGACCACACCTATGCCGAATGCTGCCTGACTGTGGTGGCCCGCGGCACGGAGGCTGTGGTCTTCAGCATCGACGGCTCCTTCACCGC
CAGCGTCTCCATCATGGGCAGCGACCCCAAGGTGCGAGCTGGCGCCGTGGACGTGGTCAGGCACTGGCAGGACTCCGGCTACCTGATCGT
GTATGTCACAGGCCGGCCGGATATGCAGAAGCACCGCGTGGTGGCATGGCTGTCGCAGCACAACTTCCCCCACGGCGTCGTCTCCTTCTG
CGACGGCCTCACCCACGACCCACTACGCCAGAAGGCAATGTTTCTGCAGAGCCTGGTGCAGGAGGTAGAACTGAACATCGTGGCCGGTTA
TGGGTCTCCCAAAGATGTGGCTGTATACGCGGCGCTGGGGCTGTCCCCGAGCCAGACCTACATCGTGGGCCGTGCCGTGCGGAAGCTACA
GGCGCAGTGCCAGTTCCTGTCAGACGGCTATGTGGCCCACCTGGGCCAGCTGGAAGCGGGCTCGCACTCGCATGCCTCCTCGGGACCCCC
GAGAGCTGCCTTGGGCAAGAGCAGCTATGGTGTGGCTGCCCCCGTGGACTTCCTGCGCAAACAGAGCCAGCTGCTTCGCTCGAGGGGCCC
CAGCCAGGCGGAGCGTGAGGGCCCGGGAACACCACCCACCACCCTGGCACGGGGCAAAGCACGGAGCATCAGCCTGAAGCTGGACAGCGA
GGAGTGAGGCCCACACCAGCCTGGACCTGGGTTATTTATTGACACACCCAAGGGGCCCGAGGGGCTGCGTGTGGGAGGCTGGGGACCCAG
ACTTTTGGCCCCAGCGCTGGCCCCCCCAGCCCCACACCCTATATCTCCGTGTGCTCCTCGGTGTTACTTCCCTTTCATATGAGGGGACCC
AGCGCCGGGGGGAGGGAGGAGGGCGTGGGCATGGGCGCAGAGGCTTTTCCAGTGTGTATAAATCCATGAAAATAAACGCCACCTGCACCC

>In-frame_ENST00000358965_ENST00000436757_TCGA-E2-A107_NUMA1_chr11_71718234_-_PITPNM1_chr11_67265793_length(amino acids)=1868AA_start in transcript=240_stop in transcript=5846
MSGITKMTLHATRGAALLSWVNSLHVADPVEAVLQLQDCSIFIKIIDRIHGTEEGQQILKQPVSERLDFVCSFLQKNRKHPSSPECLVSA
QKVLEGSELELAKMTMLLLYHSTMSSKSPRDWEQFEYKIQAELAVILKFVLDHEDGLNLNEDLENFLQKAPVPSTCSSTFPEELSPPSHQ
AKREIRFLELQKVASSSSGNNFLSGSPASPMGDILQTPQFQMRRLKKQLADERSNRDELELELAENRKLLTEKDAQIAMMQQRIDRLALL
NEKQAASPLEPKELEELRDKNESLTMRLHETLKQCQDLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEHSKATQE
WLEKQAQLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVEMLETERG
QQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQ
LAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQL
QVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVT
KGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLGEAHQAETEVLRRELAEAMAAQHTAESECE
QLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKEECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVR
AQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDRQPEWLEEQQGRQFCSTQAALQAMEREAEQMGNELERL
RAALMESQGQQQEERGQQEREVARLTQERGRAQADLALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEA
AQIKELEELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQEQADSLERSLEAERASRAERDSAL
ETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRL
VMAESEKSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAERAEELGQELKAWQEKFFQKEQALS
TLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKASYA
EQLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQ
RFQEERQKLTAQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQN
QELQEQLRSLEQLQKENKELRAEAERLGHELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLGKFQVATDALKSREPQAKPQL
DLSIDSLDLSCEEGTPLSITSKLPRTQPDGTSVPGEPASPISQRLPPKVESLESLYFTPIPARSQAPLESSLDSLGDVFLDSGRKTRSAR

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>In-frame_ENST00000358965_ENST00000356404_TCGA-E2-A107_NUMA1_chr11_71718234_-_PITPNM1_chr11_67265793_length(transcript)=8194nt_BP=5679nt
GCCCACGAAGAGGTACGATTCCGGAGAATCGCGAGGCAGAGCGGGAGCGCGCAGCCAGGTGGAAACTAATTCTAAGCCAGACTGCTGGAG
ATCACCCTGTTCTAGTGTGTGGAGGCTTCCACCAGGAGTCTGGAGTGCAATGGCACGATCTCGGCTCACTGCAACCTCCACCTCCCAGGT
TCAAGCGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGCGCATTGGAGTGACTGTCTGGCATCACCAAGATGACACTCCAC
GCCACCCGGGGGGCTGCACTCCTCTCTTGGGTGAACAGTCTACACGTGGCTGACCCTGTGGAGGCTGTGCTGCAGCTCCAGGACTGCAGC
ATCTTCATCAAGATCATTGACAGAATCCATGGCACTGAAGAGGGACAGCAAATCTTGAAGCAGCCGGTGTCAGAGAGACTGGACTTTGTG
TGCAGTTTTCTGCAGAAAAATCGAAAACATCCCTCTTCCCCAGAATGCCTGGTATCTGCACAGAAGGTGCTAGAGGGATCAGAGCTGGAA
CTGGCGAAGATGACCATGCTGCTCTTATACCACTCTACCATGAGCTCCAAAAGTCCCAGGGACTGGGAACAGTTTGAATATAAAATTCAG
GCTGAGTTGGCTGTCATTCTTAAATTTGTGCTGGACCATGAGGACGGGCTAAACCTTAATGAGGACCTAGAGAACTTCCTACAGAAAGCT
CCTGTGCCTTCTACCTGTTCTAGCACATTCCCTGAAGAGCTCTCCCCACCTAGCCACCAGGCCAAGAGGGAGATTCGCTTCCTAGAGCTA
CAGAAGGTTGCCTCCTCTTCCAGTGGGAACAACTTTCTCTCAGGTTCTCCAGCTTCTCCCATGGGTGATATCCTGCAGACCCCACAGTTC
CAGATGAGACGGCTGAAGAAGCAGCTTGCTGATGAGAGAAGTAATAGGGATGAGCTGGAGCTGGAGCTAGCTGAGAACCGCAAGCTCCTC
ACCGAGAAGGATGCACAGATAGCCATGATGCAGCAGCGCATTGACCGCCTAGCCCTGCTGAATGAGAAGCAGGCGGCCAGCCCACTGGAG
CCCAAGGAGCTTGAGGAGCTGCGTGACAAGAATGAGAGCCTTACCATGCGGCTGCATGAAACCCTGAAGCAGTGCCAGGACCTGAAGACA
GAGAAGAGCCAGATGGATCGCAAAATCAACCAGCTTTCGGAGGAGAATGGAGACCTTTCCTTTAAGCTGCGGGAGTTTGCCAGTCATCTG
CAGCAGCTACAGGATGCCCTCAATGAGCTGACGGAGGAGCACAGCAAGGCCACTCAGGAGTGGCTAGAGAAGCAGGCCCAGCTGGAGAAG
GAGCTCAGCGCAGCCCTGCAGGACAAGAAATGCCTTGAAGAGAAGAACGAAATCCTTCAGGGAAAACTTTCACAGCTGGAAGAACACTTG
TCCCAGCTGCAGGATAACCCACCCCAGGAGAAGGGCGAGGTGCTGGGTGATGTCTTGCAGCTGGAAACCTTGAAGCAAGAGGCAGCCACT
CTTGCTGCAAACAACACACAGCTCCAAGCCAGGGTAGAGATGCTGGAGACTGAGCGAGGCCAGCAGGAAGCCAAGCTGCTTGCTGAGCGG
GGCCACTTCGAAGAAGAAAAGCAGCAGCTGTCTAGCCTGATCACTGACCTGCAGAGCTCCATCTCCAACCTCAGCCAGGCCAAGGAAGAG
CTGGAGCAGGCCTCCCAGGCTCATGGGGCCCGGTTGACTGCCCAGGTGGCCTCTCTGACCTCTGAGCTCACCACACTCAATGCCACCATC
CAGCAACAGGATCAAGAACTGGCTGGCCTGAAGCAGCAGGCCAAAGAGAAGCAGGCCCAGCTAGCACAGACCCTCCAACAGCAAGAACAG
GCCTCCCAGGGCCTCCGCCACCAGGTGGAGCAGCTAAGCAGTAGCCTGAAGCAGAAGGAGCAGCAGTTGAAGGAGGTAGCGGAGAAGCAG
GAGGCAACTAGGCAGGACCATGCCCAGCAACTGGCCACTGCTGCAGAGGAGCGAGAGGCCTCCTTAAGGGAGCGGGATGCGGCTCTCAAG
CAGCTGGAGGCACTGGAGAAGGAGAAGGCTGCCAAGCTGGAGATTCTGCAGCAGCAACTTCAGGTGGCTAATGAAGCCCGGGACAGTGCC
CAGACCTCAGTGACACAGGCCCAGCGGGAGAAGGCAGAGCTGAGCCGGAAGGTGGAGGAACTCCAGGCCTGTGTTGAGACAGCCCGCCAG
GAACAGCATGAGGCCCAGGCCCAGGTTGCAGAGCTAGAGTTGCAGCTGCGGTCTGAGCAGCAAAAAGCAACTGAGAAAGAAAGGGTGGCC
CAGGAGAAGGACCAGCTCCAGGAGCAGCTCCAGGCCCTCAAAGAGTCCTTGAAGGTCACCAAGGGCAGCCTTGAAGAGGAGAAGCGCAGG
GCTGCAGATGCCCTGGAAGAGCAGCAGCGTTGTATCTCTGAGCTGAAGGCAGAGACCCGAAGCCTGGTGGAGCAGCATAAGCGGGAACGA
AAGGAGCTGGAAGAAGAGAGGGCTGGGCGCAAGGGGCTGGAGGCTCGATTACAGCAGCTTGGGGAGGCCCATCAGGCTGAGACTGAAGTC
CTGCGGCGGGAGCTGGCAGAGGCCATGGCTGCCCAGCACACAGCTGAGAGTGAGTGTGAGCAGCTCGTCAAAGAAGTAGCTGCCTGGCGT
GAGCGGTATGAGGATAGCCAGCAAGAGGAGGCACAGTATGGCGCCATGTTCCAGGAACAGCTGATGACTTTGAAGGAGGAATGTGAGAAG
GCCCGCCAGGAGCTGCAGGAGGCAAAGGAGAAGGTGGCAGGCATAGAATCCCACAGCGAGCTCCAGATAAGCCGGCAGCAGAACGAACTA
GCTGAGCTCCATGCCAACCTGGCCAGAGCACTCCAGCAGGTCCAAGAGAAGGAAGTCAGGGCCCAGAAGCTTGCAGATGACCTCTCCACT
CTGCAGGAAAAGATGGCTGCCACCAGCAAAGAGGTGGCCCGCTTGGAGACCTTGGTGCGCAAGGCAGGTGAGCAGCAGGAAACAGCCTCC
CGGGAGTTAGTCAAGGAGCCTGCGAGGGCAGGAGACAGACAGCCCGAGTGGCTGGAAGAGCAACAGGGACGCCAGTTCTGCAGCACACAG
GCAGCGCTGCAGGCTATGGAGCGGGAGGCAGAGCAGATGGGCAATGAGCTGGAACGGCTGCGGGCCGCGCTGATGGAGAGCCAGGGGCAG
CAGCAGGAGGAGCGTGGGCAGCAGGAAAGGGAGGTGGCGCGGCTGACCCAGGAGCGGGGCCGTGCCCAGGCTGACCTTGCCCTGGAGAAG
GCGGCCAGAGCAGAGCTTGAGATGCGGCTGCAGAACGCCCTCAACGAGCAGCGTGTGGAGTTCGCTACCCTGCAAGAGGCACTGGCTCAT
GCCCTGACGGAAAAGGAAGGCAAGGACCAGGAGTTGGCCAAGCTTCGTGGTCTGGAGGCAGCCCAGATAAAAGAGCTGGAGGAACTTCGG
CAAACCGTGAAGCAACTGAAGGAACAGCTGGCTAAGAAAGAAAAGGAGCACGCATCTGGCTCAGGAGCCCAATCTGAGGCTGCTGGCAGG
ACAGAGCCAACAGGCCCCAAGCTGGAGGCACTGCGGGCAGAGGTGAGCAAGCTGGAACAGCAATGCCAGAAGCAGCAGGAGCAGGCTGAC
AGCCTGGAACGCAGCCTCGAGGCTGAGCGGGCCTCCCGGGCTGAGCGGGACAGTGCTCTGGAGACTCTGCAGGGCCAGTTAGAGGAGAAG
GCCCAGGAGCTAGGGCACAGTCAGAGTGCCTTAGCCTCGGCCCAACGGGAGTTGGCTGCCTTCCGCACCAAGGTACAAGACCACAGCAAG
GCTGAAGATGAGTGGAAGGCCCAGGTGGCCCGGGGCCGGCAAGAGGCTGAGAGGAAAAATAGCCTCATCAGCAGCTTGGAGGAGGAGGTG
TCCATCCTGAATCGCCAGGTCCTGGAGAAGGAGGGGGAGAGCAAGGAGTTGAAGCGGCTGGTGATGGCCGAGTCAGAGAAGAGCCAGAAG
CTGGAGGAGAGGCTGCGCCTGCTGCAGGCAGAGACAGCCAGCAACAGTGCCAGAGCTGCAGAACGCAGCTCTGCTCTGCGGGAGGAGGTG
CAGAGCCTCCGGGAGGAGGCTGAGAAACAGCGGGTGGCTTCAGAGAACCTGCGGCAGGAGCTGACCTCACAGGCTGAGCGTGCGGAGGAG
CTGGGCCAAGAATTGAAGGCGTGGCAGGAGAAGTTCTTCCAGAAAGAGCAGGCCCTCTCCACCCTGCAGCTCGAGCACACCAGCACACAG
GCCCTGGTGAGTGAGCTGCTGCCAGCTAAGCACCTCTGCCAGCAGCTGCAGGCCGAGCAGGCCGCTGCCGAGAAACGCCACCGTGAGGAG
CTGGAGCAGAGCAAGCAGGCCGCTGGGGGACTGCGGGCAGAGCTGCTGCGGGCCCAGCGGGAGCTTGGGGAGCTGATTCCTCTGCGGCAG
AAGGTGGCAGAGCAGGAGCGAACAGCTCAGCAGCTGCGGGCAGAGAAGGCCAGCTATGCAGAGCAGCTGAGCATGCTGAAGAAGGCGCAT
GGCCTGCTGGCAGAGGAGAACCGGGGGCTGGGTGAGCGGGCCAACCTTGGCCGGCAGTTTCTGGAAGTGGAGTTGGACCAGGCCCGGGAG
AAGTATGTCCAAGAGTTGGCAGCCGTACGTGCTGATGCTGAGACCCGTCTGGCTGAGGTGCAGCGAGAAGCACAGAGCACTGCCCGGGAG
CTGGAGGTGATGACTGCCAAGTATGAGGGTGCCAAGGTCAAGGTCCTGGAGGAGAGGCAGCGGTTCCAGGAAGAGAGGCAGAAACTCACT
GCCCAGGTGGAAGAACTGAGTAAGAAACTGGCTGACTCTGACCAAGCCAGCAAGGTGCAGCAGCAGAAGCTGAAGGCTGTCCAGGCTCAG
GGAGGCGAGAGCCAGCAGGAGGCCCAGCGCCTCCAGGCCCAGCTGAATGAACTGCAAGCCCAGTTGAGCCAGAAGGAGCAGGCAGCTGAG
CACTATAAGCTGCAGATGGAGAAAGCCAAAACACATTATGATGCCAAGAAGCAGCAGAACCAAGAGCTGCAGGAGCAGCTGCGGAGCCTG
GAGCAGCTGCAGAAGGAAAACAAAGAGCTGCGAGCTGAAGCTGAACGGCTGGGCCATGAGCTACAGCAGGCTGGGCTGAAGACCAAGGAG
GCTGAACAGACCTGCCGCCACCTTACTGCCCAGGTGCGCAGCCTGGAGGCACAGGTTGCCCATGCAGACCAGCAGCTTCGAGACCTGGGC
AAATTCCAGGTGGCAACTGATGCTTTAAAGAGCCGTGAGCCCCAGGCTAAGCCCCAGCTGGACTTGAGTATTGACAGCCTGGATCTGAGC
TGCGAGGAGGGGACCCCACTCAGTATCACCAGCAAGCTGCCTCGTACCCAGCCAGACGGCACCAGCGTCCCTGGAGAACCAGCCTCACCT
ATCTCCCAGCGCCTGCCCCCCAAGGTAGAATCCCTGGAGAGTCTCTACTTCACTCCCATCCCTGCTCGGAGTCAGGCCCCCCTGGAGAGC
AGCCTGGACTCCCTGGGAGACGTCTTCCTGGACTCGGGTCGTAAGACCCGCTCCGCTCGTCGGCGCACCACGCAGATCATCAACATCACC
ATGACCAAGCCTGAGCCCTTACAGCCACGATGGGGACAGCCTGTCTCGCTCCCAAGACCACATTCCACTGGCTGCCCTGCCACTGCTGGC
CACCTCATCCTCCCGCTACCAGGGCGCCGTGGCCACCGTCATTGCCCGCACCAACCAGGCCTACTCAGCCTTCCTGCGCTCACCTGAGGG
TGCCGGCTTCTGTGGGCAGGTCGCACTGATTGGAGATGGTGTTGGTGGCATCCTGGGCTTTGATGCACTCTGCCACAGTGCTAACGCGGG
CACCGGGAGTCGGGGCAGCAGCCGCCGTGGGAGCATGAACAATGAGCTGCTCTCTCCGGAGTTTGGCCCAGTGCGGGACCCCCTGGCAGA
TGGTGTGGAAGGCCTGGGTCGGGGCAGCCCAGAACCCTCGGCCTTGCCTCCCCAGCGCATCCCCAGCGACATGGCCAGTCCTGAGCCCGA
GGGCTCTCAGAACAGCCTTCAGGCAGCCCCCGCAACCACCTCCTCCTGGGAGCCCCGGCGGGCAAGCACGGCCTTCTGCCCACCCGCTGC
CAGTTCCGAGGCACCTGACGGCCCCAGCAGCACTGCCCGCCTTGACTTCAAGGTCTCTGGCTTCTTCCTCTTCGGCTCCCCACTGGGCCT
GGTGCTGGCTCTGCGCAAAACTGTGATGCCCGCCCTGGAGGCAGCCCAGATGCGCCCAGCCTGTGAACAGATCTACAACCTCTTCCACGC
GGCTGACCCCTGCGCCTCACGCCTCGAGCCCCTGCTGGCCCCGAAGTTCCAGGCCATCGCCCCACTGACCGTGCCCCGCTACCAGAAGTT
CCCCCTGGGAGATGGCTCATCCCTGCTGCTGGCCGACACTCTGCAGACGCACTCCAGCCTCTTTCTGGAGGAGCTGGAGATGCTGGTGCC
CTCAACACCCACCTCTACTAGCGGTGCCTTCTGGAAGGGCAGTGAGTTGGCCACTGACCCCCCGGCCCAGCCAGCCGCCCCCAGCACCAC
CAGTGAGGTGGTTAAGATCCTGGAGCGCTGGTGGGGGACCAAGCGGATCGACTACTCGCTGTACTGCCCCGAGGCGCTCACCGCCTTTCC
CACCGTCACGCTGCCCCACCTCTTCCACGCCAGCTACTGGGAGTCCGCCGACGTGGTGGCGTTCATCCTGCGCCAGGTGATCGAGAAGGA
GCGGCCACAGCTGGCGGAATGCGAGGAGCCGTCCATCTACAGCCCGGCCTTCCCCAGGGAGAAGTGGCAGCGAAAACGCACGCAGGTCAA
GATCCGGAACGTCACTTCCAACCACCGGGCGAGCGACACGGTGGTGTGCGAGGGCCGCCCCCAGGTGCTAAGCGGGCGCTTCATGTACGG
GCCCCTGGACGTCGTCACGCTCACTGGAGAGAAGGTGGATGTCTACATCATGACGCAGCCGCTGTCGGGCAAGTGGATCCACTTTGGCAC
CGAAGTCACCAATAGCTCGGGCCGCCTCACCTTCCCAGTTCCCCCAGAACGCGCGCTGGGCATTGGTGTCTACCCCGTGCGCATGGTGGT
CAGGGGCGACCACACCTATGCCGAATGCTGCCTGACTGTGGTGGCCCGCGGCACGGAGGCTGTGGTCTTCAGCATCGACGGCTCCTTCAC
CGCCAGCGTCTCCATCATGGGCAGCGACCCCAAGGTGCGAGCTGGCGCCGTGGACGTGGTCAGGCACTGGCAGGACTCCGGCTACCTGAT
CGTGTATGTCACAGGCCGGCCGGATATGCAGAAGCACCGCGTGGTGGCATGGCTGTCGCAGCACAACTTCCCCCACGGCGTCGTCTCCTT
CTGCGACGGCCTCACCCACGACCCACTACGCCAGAAGGCAATGTTTCTGCAGAGCCTGGTGCAGGAGGTAGAACTGAACATCGTGGCCGG
TTATGGGTCTCCCAAAGATGTGGCTGTATACGCGGCGCTGGGGCTGTCCCCGAGCCAGACCTACATCGTGGGCCGTGCCGTGCGGAAGCT
ACAGGCGCAGTGCCAGTTCCTGTCAGACGGCTATGTGGCCCACCTGGGCCAGCTGGAAGCGGGCTCGCACTCGCATGCCTCCTCGGGACC
CCCGAGAGCTGCCTTGGGCAAGAGCAGCTATGGTGTGGCTGCCCCCGTGGACTTCCTGCGCAAACAGAGCCAGCTGCTTCGCTCGAGGGG
CCCCAGCCAGGCGGAGCGTGAGGGCCCGGGAACACCACCCACCACCCTGGCACGGGGCAAAGCACGGAGCATCAGCCTGAAGCTGGACAG
CGAGGAGTGAGGCCCACACCAGCCTGGACCTGGGTTATTTATTGACACACCCAAGGGGCCCGAGGGGCTGCGTGTGGGAGGCTGGGGACC
CAGACTTTTGGCCCCAGCGCTGGCCCCCCCAGCCCCACACCCTATATCTCCGTGTGCTCCTCGGTGTTACTTCCCTTTCATATGAGGGGA
CCCAGCGCCGGGGGGAGGGAGGAGGGCGTGGGCATGGGCGCAGAGGCTTTTCCAGTGTGTATAAATCCATGAAAATAAACGCCACCTGCA

>In-frame_ENST00000358965_ENST00000356404_TCGA-E2-A107_NUMA1_chr11_71718234_-_PITPNM1_chr11_67265793_length(amino acids)=1868AA_start in transcript=240_stop in transcript=5846
MSGITKMTLHATRGAALLSWVNSLHVADPVEAVLQLQDCSIFIKIIDRIHGTEEGQQILKQPVSERLDFVCSFLQKNRKHPSSPECLVSA
QKVLEGSELELAKMTMLLLYHSTMSSKSPRDWEQFEYKIQAELAVILKFVLDHEDGLNLNEDLENFLQKAPVPSTCSSTFPEELSPPSHQ
AKREIRFLELQKVASSSSGNNFLSGSPASPMGDILQTPQFQMRRLKKQLADERSNRDELELELAENRKLLTEKDAQIAMMQQRIDRLALL
NEKQAASPLEPKELEELRDKNESLTMRLHETLKQCQDLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEHSKATQE
WLEKQAQLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVEMLETERG
QQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQ
LAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQL
QVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVT
KGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLGEAHQAETEVLRRELAEAMAAQHTAESECE
QLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKEECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVR
AQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDRQPEWLEEQQGRQFCSTQAALQAMEREAEQMGNELERL
RAALMESQGQQQEERGQQEREVARLTQERGRAQADLALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEA
AQIKELEELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQEQADSLERSLEAERASRAERDSAL
ETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRL
VMAESEKSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAERAEELGQELKAWQEKFFQKEQALS
TLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKASYA
EQLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQ
RFQEERQKLTAQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQN
QELQEQLRSLEQLQKENKELRAEAERLGHELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLGKFQVATDALKSREPQAKPQL
DLSIDSLDLSCEEGTPLSITSKLPRTQPDGTSVPGEPASPISQRLPPKVESLESLYFTPIPARSQAPLESSLDSLGDVFLDSGRKTRSAR

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Fusion Gene PPI Analysis for NUMA1-PITPNM1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for NUMA1-PITPNM1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for NUMA1-PITPNM1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneNUMA1C0023487Acute Promyelocytic Leukemia1CTD_human;ORPHANET
HgeneNUMA1C0162820Dermatitis, Allergic Contact1CTD_human
TgenePITPNM1C0036341Schizophrenia1CTD_human