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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:NUMA1-YAP1 (FusionGDB2 ID:60551)

Fusion Gene Summary for NUMA1-YAP1

check button Fusion gene summary
Fusion gene informationFusion gene name: NUMA1-YAP1
Fusion gene ID: 60551
HgeneTgene
Gene symbol

NUMA1

YAP1

Gene ID

4926

10413

Gene namenuclear mitotic apparatus protein 1Yes1 associated transcriptional regulator
SynonymsNMP-22|NUMACOB1|YAP|YAP2|YAP65|YKI
Cytomap

11q13.4

11q22.1

Type of geneprotein-codingprotein-coding
Descriptionnuclear mitotic apparatus protein 1SP-H antigencentrophilin stabilizes mitotic spindle in mitotic cellsnuclear matrix protein-22structural nuclear proteintranscriptional coactivator YAP165 kDa Yes-associated proteinYes associated protein 1protein yorkie homologyes-associated protein 1yes-associated protein 2yes-associated protein YAP65 homologyorkie homolog
Modification date2020031320200329
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000351960, ENST00000358965, 
ENST00000393695, ENST00000543450, 
ENST00000526343, ENST00000282441, 
ENST00000537274, ENST00000345877, 
ENST00000531439, ENST00000524575, 
ENST00000528834, 
Fusion gene scores* DoF score36 X 22 X 17=1346420 X 10 X 13=2600
# samples 4321
** MAII scorelog2(43/13464*10)=-4.96862661174049
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(21/2600*10)=-3.63005039024969
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: NUMA1 [Title/Abstract] AND YAP1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointNUMA1(71746948)-YAP1(102094353), # samples:2
Anticipated loss of major functional domain due to fusion event.NUMA1-YAP1 seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF.
NUMA1-YAP1 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
NUMA1-YAP1 seems lost the major protein functional domain in Tgene partner, which is a tumor suppressor due to the frame-shifted ORF.
NUMA1-YAP1 seems lost the major protein functional domain in Tgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneNUMA1

GO:0000132

establishment of mitotic spindle orientation

21816348

HgeneNUMA1

GO:0030953

astral microtubule organization

12445386

HgeneNUMA1

GO:0060236

regulation of mitotic spindle organization

26195665

HgeneNUMA1

GO:1902365

positive regulation of protein localization to spindle pole body

16076287

TgeneYAP1

GO:0006974

cellular response to DNA damage stimulus

18280240

TgeneYAP1

GO:0008283

cell proliferation

17974916

TgeneYAP1

GO:0032570

response to progesterone

16772533

TgeneYAP1

GO:0033148

positive regulation of intracellular estrogen receptor signaling pathway

16772533

TgeneYAP1

GO:0045893

positive regulation of transcription, DNA-templated

20368466

TgeneYAP1

GO:0045944

positive regulation of transcription by RNA polymerase II

25796446

TgeneYAP1

GO:0050767

regulation of neurogenesis

25433207

TgeneYAP1

GO:0050847

progesterone receptor signaling pathway

16772533

TgeneYAP1

GO:0060242

contact inhibition

17974916

TgeneYAP1

GO:0065003

protein-containing complex assembly

20368466

TgeneYAP1

GO:0071480

cellular response to gamma radiation

18280240

TgeneYAP1

GO:0072091

regulation of stem cell proliferation

25433207


check buttonFusion gene breakpoints across NUMA1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across YAP1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SKCMTCGA-GN-A4U7-06ANUMA1chr11

71746948

-YAP1chr11

102094353

+
ChimerDB4SKCMTCGA-GN-A4U7-06ANUMA1chr11

71746948

-YAP1chr11

102094353

+


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Fusion Gene ORF analysis for NUMA1-YAP1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000351960ENST00000526343NUMA1chr11

71746948

-YAP1chr11

102094353

+
In-frameENST00000351960ENST00000282441NUMA1chr11

71746948

-YAP1chr11

102094353

+
In-frameENST00000351960ENST00000537274NUMA1chr11

71746948

-YAP1chr11

102094353

+
In-frameENST00000351960ENST00000345877NUMA1chr11

71746948

-YAP1chr11

102094353

+
In-frameENST00000351960ENST00000531439NUMA1chr11

71746948

-YAP1chr11

102094353

+
In-frameENST00000351960ENST00000524575NUMA1chr11

71746948

-YAP1chr11

102094353

+
5CDS-intronENST00000351960ENST00000528834NUMA1chr11

71746948

-YAP1chr11

102094353

+
Frame-shiftENST00000358965ENST00000526343NUMA1chr11

71746948

-YAP1chr11

102094353

+
Frame-shiftENST00000358965ENST00000282441NUMA1chr11

71746948

-YAP1chr11

102094353

+
Frame-shiftENST00000358965ENST00000537274NUMA1chr11

71746948

-YAP1chr11

102094353

+
Frame-shiftENST00000358965ENST00000345877NUMA1chr11

71746948

-YAP1chr11

102094353

+
Frame-shiftENST00000358965ENST00000531439NUMA1chr11

71746948

-YAP1chr11

102094353

+
Frame-shiftENST00000358965ENST00000524575NUMA1chr11

71746948

-YAP1chr11

102094353

+
5CDS-intronENST00000358965ENST00000528834NUMA1chr11

71746948

-YAP1chr11

102094353

+
In-frameENST00000393695ENST00000526343NUMA1chr11

71746948

-YAP1chr11

102094353

+
In-frameENST00000393695ENST00000282441NUMA1chr11

71746948

-YAP1chr11

102094353

+
In-frameENST00000393695ENST00000537274NUMA1chr11

71746948

-YAP1chr11

102094353

+
In-frameENST00000393695ENST00000345877NUMA1chr11

71746948

-YAP1chr11

102094353

+
In-frameENST00000393695ENST00000531439NUMA1chr11

71746948

-YAP1chr11

102094353

+
In-frameENST00000393695ENST00000524575NUMA1chr11

71746948

-YAP1chr11

102094353

+
5CDS-intronENST00000393695ENST00000528834NUMA1chr11

71746948

-YAP1chr11

102094353

+
intron-3CDSENST00000543450ENST00000526343NUMA1chr11

71746948

-YAP1chr11

102094353

+
intron-3CDSENST00000543450ENST00000282441NUMA1chr11

71746948

-YAP1chr11

102094353

+
intron-3CDSENST00000543450ENST00000537274NUMA1chr11

71746948

-YAP1chr11

102094353

+
intron-3CDSENST00000543450ENST00000345877NUMA1chr11

71746948

-YAP1chr11

102094353

+
intron-3CDSENST00000543450ENST00000531439NUMA1chr11

71746948

-YAP1chr11

102094353

+
intron-3CDSENST00000543450ENST00000524575NUMA1chr11

71746948

-YAP1chr11

102094353

+
intron-intronENST00000543450ENST00000528834NUMA1chr11

71746948

-YAP1chr11

102094353

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000351960NUMA1chr1171746948-ENST00000526343YAP1chr11102094353+1349214154696180
ENST00000351960NUMA1chr1171746948-ENST00000282441YAP1chr11102094353+4180214154696180
ENST00000351960NUMA1chr1171746948-ENST00000537274YAP1chr11102094353+4180214154696180
ENST00000351960NUMA1chr1171746948-ENST00000345877YAP1chr11102094353+4180214154696180
ENST00000351960NUMA1chr1171746948-ENST00000531439YAP1chr11102094353+720214154696180
ENST00000351960NUMA1chr1171746948-ENST00000524575YAP1chr11102094353+909214154696180
ENST00000393695NUMA1chr1171746948-ENST00000526343YAP1chr11102094353+1509374314856180
ENST00000393695NUMA1chr1171746948-ENST00000282441YAP1chr11102094353+4340374314856180
ENST00000393695NUMA1chr1171746948-ENST00000537274YAP1chr11102094353+4340374314856180
ENST00000393695NUMA1chr1171746948-ENST00000345877YAP1chr11102094353+4340374314856180
ENST00000393695NUMA1chr1171746948-ENST00000531439YAP1chr11102094353+880374314856180
ENST00000393695NUMA1chr1171746948-ENST00000524575YAP1chr11102094353+1069374314856180

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000351960ENST00000526343NUMA1chr1171746948-YAP1chr11102094353+0.0019922530.9980077
ENST00000351960ENST00000282441NUMA1chr1171746948-YAP1chr11102094353+0.002511980.997488
ENST00000351960ENST00000537274NUMA1chr1171746948-YAP1chr11102094353+0.002511980.997488
ENST00000351960ENST00000345877NUMA1chr1171746948-YAP1chr11102094353+0.002511980.997488
ENST00000351960ENST00000531439NUMA1chr1171746948-YAP1chr11102094353+0.003758780.9962412
ENST00000351960ENST00000524575NUMA1chr1171746948-YAP1chr11102094353+0.0027823070.99721766
ENST00000393695ENST00000526343NUMA1chr1171746948-YAP1chr11102094353+0.002943750.99705625
ENST00000393695ENST00000282441NUMA1chr1171746948-YAP1chr11102094353+0.002597280.9974027
ENST00000393695ENST00000537274NUMA1chr1171746948-YAP1chr11102094353+0.002597280.9974027
ENST00000393695ENST00000345877NUMA1chr1171746948-YAP1chr11102094353+0.002597280.9974027
ENST00000393695ENST00000531439NUMA1chr1171746948-YAP1chr11102094353+0.0050583470.99494165
ENST00000393695ENST00000524575NUMA1chr1171746948-YAP1chr11102094353+0.0045137420.9954862

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Fusion Genomic Features for NUMA1-YAP1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
NUMA1chr1171746947-YAP1chr11102094352+1.86E-070.99999976
NUMA1chr1171746947-YAP1chr11102094352+1.86E-070.99999976

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for NUMA1-YAP1


check button Go to

FGviewer for the breakpoints of chr11:71746948-chr11:102094353

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneYAP1chr11:71746948chr11:102094353ENST0000034587737298_359294.0455.0Coiled coilOntology_term=ECO:0000255
TgeneYAP1chr11:71746948chr11:102094353ENST0000052457559298_359166.0327.0Coiled coilOntology_term=ECO:0000255
TgeneYAP1chr11:71746948chr11:102094353ENST0000052634337298_359290.0451.0Coiled coilOntology_term=ECO:0000255
TgeneYAP1chr11:71746948chr11:102094353ENST0000052457559171_204166.0327.0DomainWW 1
TgeneYAP1chr11:71746948chr11:102094353ENST0000052457559230_263166.0327.0DomainWW 2
TgeneYAP1chr11:71746948chr11:102094353ENST0000034587737291_504294.0455.0RegionNote=Transactivation domain
TgeneYAP1chr11:71746948chr11:102094353ENST0000052457559291_504166.0327.0RegionNote=Transactivation domain
TgeneYAP1chr11:71746948chr11:102094353ENST0000052634337291_504290.0451.0RegionNote=Transactivation domain

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNUMA1chr11:71746948chr11:102094353ENST00000358965-427213_169914.02102.0Coiled coilOntology_term=ECO:0000255
HgeneNUMA1chr11:71746948chr11:102094353ENST00000393695-327213_169914.02116.0Coiled coilOntology_term=ECO:0000255
HgeneNUMA1chr11:71746948chr11:102094353ENST00000358965-4271742_174814.02102.0MotifTankyrase-binding domain
HgeneNUMA1chr11:71746948chr11:102094353ENST00000358965-4271984_198914.02102.0MotifNuclear localization signal
HgeneNUMA1chr11:71746948chr11:102094353ENST00000393695-3271742_174814.02116.0MotifTankyrase-binding domain
HgeneNUMA1chr11:71746948chr11:102094353ENST00000393695-3271984_198914.02116.0MotifNuclear localization signal
HgeneNUMA1chr11:71746948chr11:102094353ENST00000358965-4271699_187614.02102.0RegionMembrane-binding domain 1
HgeneNUMA1chr11:71746948chr11:102094353ENST00000358965-4271700_211514.02102.0RegionNote=Tail (Globular)
HgeneNUMA1chr11:71746948chr11:102094353ENST00000358965-4271788_181014.02102.0Region4.1-binding domain
HgeneNUMA1chr11:71746948chr11:102094353ENST00000358965-4271882_198514.02102.0RegionTubulin-binding domain
HgeneNUMA1chr11:71746948chr11:102094353ENST00000358965-4271892_192614.02102.0RegionGPSM2-binding domain
HgeneNUMA1chr11:71746948chr11:102094353ENST00000358965-4271981_206014.02102.0RegionMembrane-binding domain 2
HgeneNUMA1chr11:71746948chr11:102094353ENST00000358965-4271_21214.02102.0RegionNote=Head (Globular)
HgeneNUMA1chr11:71746948chr11:102094353ENST00000393695-3271699_187614.02116.0RegionMembrane-binding domain 1
HgeneNUMA1chr11:71746948chr11:102094353ENST00000393695-3271700_211514.02116.0RegionNote=Tail (Globular)
HgeneNUMA1chr11:71746948chr11:102094353ENST00000393695-3271788_181014.02116.0Region4.1-binding domain
HgeneNUMA1chr11:71746948chr11:102094353ENST00000393695-3271882_198514.02116.0RegionTubulin-binding domain
HgeneNUMA1chr11:71746948chr11:102094353ENST00000393695-3271892_192614.02116.0RegionGPSM2-binding domain
HgeneNUMA1chr11:71746948chr11:102094353ENST00000393695-3271981_206014.02116.0RegionMembrane-binding domain 2
HgeneNUMA1chr11:71746948chr11:102094353ENST00000393695-3271_21214.02116.0RegionNote=Head (Globular)
TgeneYAP1chr11:71746948chr11:102094353ENST0000028244159298_359344.0505.0Coiled coilOntology_term=ECO:0000255
TgeneYAP1chr11:71746948chr11:102094353ENST000002824415986_100344.0505.0Coiled coilOntology_term=ECO:0000269
TgeneYAP1chr11:71746948chr11:102094353ENST000003458773786_100294.0455.0Coiled coilOntology_term=ECO:0000269
TgeneYAP1chr11:71746948chr11:102094353ENST000005245755986_100166.0327.0Coiled coilOntology_term=ECO:0000269
TgeneYAP1chr11:71746948chr11:102094353ENST000005263433786_100290.0451.0Coiled coilOntology_term=ECO:0000269
TgeneYAP1chr11:71746948chr11:102094353ENST0000053143948298_359328.0489.0Coiled coilOntology_term=ECO:0000255
TgeneYAP1chr11:71746948chr11:102094353ENST000005314394886_100328.0489.0Coiled coilOntology_term=ECO:0000269
TgeneYAP1chr11:71746948chr11:102094353ENST0000053727448298_359332.0493.0Coiled coilOntology_term=ECO:0000255
TgeneYAP1chr11:71746948chr11:102094353ENST000005372744886_100332.0493.0Coiled coilOntology_term=ECO:0000269
TgeneYAP1chr11:71746948chr11:102094353ENST00000282441593_49344.0505.0Compositional biasNote=Pro-rich
TgeneYAP1chr11:71746948chr11:102094353ENST00000345877373_49294.0455.0Compositional biasNote=Pro-rich
TgeneYAP1chr11:71746948chr11:102094353ENST00000524575593_49166.0327.0Compositional biasNote=Pro-rich
TgeneYAP1chr11:71746948chr11:102094353ENST00000526343373_49290.0451.0Compositional biasNote=Pro-rich
TgeneYAP1chr11:71746948chr11:102094353ENST00000531439483_49328.0489.0Compositional biasNote=Pro-rich
TgeneYAP1chr11:71746948chr11:102094353ENST00000537274483_49332.0493.0Compositional biasNote=Pro-rich
TgeneYAP1chr11:71746948chr11:102094353ENST0000028244159171_204344.0505.0DomainWW 1
TgeneYAP1chr11:71746948chr11:102094353ENST0000028244159230_263344.0505.0DomainWW 2
TgeneYAP1chr11:71746948chr11:102094353ENST0000034587737171_204294.0455.0DomainWW 1
TgeneYAP1chr11:71746948chr11:102094353ENST0000034587737230_263294.0455.0DomainWW 2
TgeneYAP1chr11:71746948chr11:102094353ENST0000052634337171_204290.0451.0DomainWW 1
TgeneYAP1chr11:71746948chr11:102094353ENST0000052634337230_263290.0451.0DomainWW 2
TgeneYAP1chr11:71746948chr11:102094353ENST0000053143948171_204328.0489.0DomainWW 1
TgeneYAP1chr11:71746948chr11:102094353ENST0000053143948230_263328.0489.0DomainWW 2
TgeneYAP1chr11:71746948chr11:102094353ENST0000053727448171_204332.0493.0DomainWW 1
TgeneYAP1chr11:71746948chr11:102094353ENST0000053727448230_263332.0493.0DomainWW 2
TgeneYAP1chr11:71746948chr11:102094353ENST0000028244159291_504344.0505.0RegionNote=Transactivation domain
TgeneYAP1chr11:71746948chr11:102094353ENST0000053143948291_504328.0489.0RegionNote=Transactivation domain
TgeneYAP1chr11:71746948chr11:102094353ENST0000053727448291_504332.0493.0RegionNote=Transactivation domain


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Fusion Gene Sequence for NUMA1-YAP1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000351960_ENST00000526343_TCGA-GN-A4U7-06A_NUMA1_chr11_71746948_-_YAP1_chr11_102094353_length(transcript)=1349nt_BP=214nt
GTGCTGGAGAGGCCGCTGCGAGCGGAAGGCCTCCTCCATAACCGAGTCCGAAAGGGCAGAATCTATGGGGGTGGAAACTAATTCTAAGCC
AGACTGCTGGAGATCACCCTGTTCTAGTGTGTGGAGGCTTCCACCAGGAGGCGCATTGGAGTGACTGTCTGGCATCACCAAGATGACACT
CCACGCCACCCGGGGGGCTGCACTCCTCTCTTGGGAGTTAGCCCTGCGTAGCCAGTTACCAACACTGGAGCAGGATGGTGGGACTCAAAA
TCCAGTGTCTTCTCCCGGGATGTCTCAGGAATTGAGAACAATGACGACCAATAGCTCAGATCCTTTCCTTAACAGTGGCACCTATCACTC
TCGAGATGAGAGTACAGACAGTGGACTAAGCATGAGCAGCTACAGTGTCCCTCGAACCCCAGATGACTTCCTGAACAGTGTGGATGAGAT
GGATACAGGTGATACTATCAACCAAAGCACCCTGCCCTCACAGCAGAACCGTTTCCCAGACTACCTTGAAGCCATTCCTGGGACAAATGT
GGACCTTGGAACACTGGAAGGAGATGGAATGAACATAGAAGGAGAGGAGCTGATGCCAAGTCTGCAGGAAGCTTTGAGTTCTGACATCCT
TAATGACATGGAGTCTGTTTTGGCTGCCACCAAGCTAGATAAAGAAAGCTTTCTTACATGGTTATAGAGCCCTCAGGCAGACTGAATTCT
AAATCTGTGAAGGATCTAAGGAGACACATGCACCGGAAATTTCCATAAGCCAGTTGCAGTTTTCAGGCTAATACAGAAAAAGATGAACAA
ACGTCCAGCAAGATACTTTAATCCTCTATTTTGCTCTTCCTTGTCCATTGCTGCTGTTAATGTATTGCTGACCTCTTTCACAGTTGGCTC
TAAAGAATCAAAAGAAAAAAACTTTTTATTTCTTTTGCTATTAAAACTACTGTTCATTTTGGGGGCTGGGGGAAGTGAGCCTGTTTGGAT
GATGGATGCCATTCCTTTTGCCCAGTTAAATGTTCACCAATCATTTTAACTAAATACTCAGACTTAGAAGTCAGATGCTTCATGTCACAG
CATTTAGTTTGTTCAACAGTTGTTTCTTCAGCTTCCTTTGTCCAGTGGAAAAACATGATTTACTGGTCTGACAAGCCAAAAATGTTATAT
CTGATATTAAATACTTAATGCTGATTTGAAGAGATAGCTGAAACCAAGGCTGAAGACTGTTTTACTTTCAGTATTTTCTTTTCCTCCTAG

>In-frame_ENST00000351960_ENST00000526343_TCGA-GN-A4U7-06A_NUMA1_chr11_71746948_-_YAP1_chr11_102094353_length(amino acids)=180AA_start in transcript=154_stop in transcript=696
MSGITKMTLHATRGAALLSWELALRSQLPTLEQDGGTQNPVSSPGMSQELRTMTTNSSDPFLNSGTYHSRDESTDSGLSMSSYSVPRTPD
DFLNSVDEMDTGDTINQSTLPSQQNRFPDYLEAIPGTNVDLGTLEGDGMNIEGEELMPSLQEALSSDILNDMESVLAATKLDKESFLTWL

--------------------------------------------------------------
>In-frame_ENST00000351960_ENST00000282441_TCGA-GN-A4U7-06A_NUMA1_chr11_71746948_-_YAP1_chr11_102094353_length(transcript)=4180nt_BP=214nt
GTGCTGGAGAGGCCGCTGCGAGCGGAAGGCCTCCTCCATAACCGAGTCCGAAAGGGCAGAATCTATGGGGGTGGAAACTAATTCTAAGCC
AGACTGCTGGAGATCACCCTGTTCTAGTGTGTGGAGGCTTCCACCAGGAGGCGCATTGGAGTGACTGTCTGGCATCACCAAGATGACACT
CCACGCCACCCGGGGGGCTGCACTCCTCTCTTGGGAGTTAGCCCTGCGTAGCCAGTTACCAACACTGGAGCAGGATGGTGGGACTCAAAA
TCCAGTGTCTTCTCCCGGGATGTCTCAGGAATTGAGAACAATGACGACCAATAGCTCAGATCCTTTCCTTAACAGTGGCACCTATCACTC
TCGAGATGAGAGTACAGACAGTGGACTAAGCATGAGCAGCTACAGTGTCCCTCGAACCCCAGATGACTTCCTGAACAGTGTGGATGAGAT
GGATACAGGTGATACTATCAACCAAAGCACCCTGCCCTCACAGCAGAACCGTTTCCCAGACTACCTTGAAGCCATTCCTGGGACAAATGT
GGACCTTGGAACACTGGAAGGAGATGGAATGAACATAGAAGGAGAGGAGCTGATGCCAAGTCTGCAGGAAGCTTTGAGTTCTGACATCCT
TAATGACATGGAGTCTGTTTTGGCTGCCACCAAGCTAGATAAAGAAAGCTTTCTTACATGGTTATAGAGCCCTCAGGCAGACTGAATTCT
AAATCTGTGAAGGATCTAAGGAGACACATGCACCGGAAATTTCCATAAGCCAGTTGCAGTTTTCAGGCTAATACAGAAAAAGATGAACAA
ACGTCCAGCAAGATACTTTAATCCTCTATTTTGCTCTTCCTTGTCCATTGCTGCTGTTAATGTATTGCTGACCTCTTTCACAGTTGGCTC
TAAAGAATCAAAAGAAAAAAACTTTTTATTTCTTTTGCTATTAAAACTACTGTTCATTTTGGGGGCTGGGGGAAGTGAGCCTGTTTGGAT
GATGGATGCCATTCCTTTTGCCCAGTTAAATGTTCACCAATCATTTTAACTAAATACTCAGACTTAGAAGTCAGATGCTTCATGTCACAG
CATTTAGTTTGTTCAACAGTTGTTTCTTCAGCTTCCTTTGTCCAGTGGAAAAACATGATTTACTGGTCTGACAAGCCAAAAATGTTATAT
CTGATATTAAATACTTAATGCTGATTTGAAGAGATAGCTGAAACCAAGGCTGAAGACTGTTTTACTTTCAGTATTTTCTTTTCCTCCTAG
TGCTATCATTAGTCACATAATGACCTTGATTTTATTTTAGGAGCTTATAAGGCATGAGACAATTTCCATATAAATATATTAATTATTGCC
ACATACTCTAATATAGATTTTGGTGGATAATTTTGTGGGTGTGCATTTTGTTCTGTTTTGTTGGGTTTTTTGTTTTTTTTGTTTTTGGCA
GGGTCGGTGGGGGGGTTGGTTGGTTGGTTGGTTTTGTCGGAACCTAGGCAAATGACCATATTAGTGAATCTGTTAATAGTTGTAGCTTGG
GATGGTTATTGTAGTTGTTTTGGTAAAATCTTCATTTCCTGGTTTTTTTTACCACCTTATTTAAATCTCGATTATCTGCTCTCTCTTTTA
TATACATACACACACCCAAACATAACATTTATAATAGTGTGGTAGTGGAATGTATCCTTTTTTAGGTTTCCCTGCTTTCCAGTTAATTTT
TAAAATGGTAGCGCTTTGTATGCATTTAGAATACATGACTAGTAGTTTATATTTCACTGGTAGTTTAAATCTGGTTGGGGCAGTCTGCAG
ATGTTTGAAGTAGTTTAGTGTTCTAGAAAGAGCTATTACTGTGGATAGTGCCTAGGGGAGTGCTCCACGCCCTCTGGGCATACGGTAGAT
ATTATCTGATGAATTGGAAAGGAGCAAACCAGAAATGGCTTTATTTTCTCCCTTGGACTAATTTTTAAGTCTCGATTGGAATTCAGTGAG
TAGGTTCATAATGTGCATGACAGAAATAAGCTTTATAGTGGTTTACCTTCATTTAGCTTTGGAAGTTTTCTTTGCCTTAGTTTTGGAAGT
AAATTCTAGTTTGTAGTTCTCATTTGTAATGAACACATTAACGACTAGATTAAAATATTGCCTTCAAGATTGTTCTTACTTACAAGACTT
GCTCCTACTTCTATGCTGAAAATTGACCCTGGATAGAATACTATAAGGTTTTGAGTTAGCTGGAAAAGTGATCAGATTAATAAATGTATA
TTGGTAGTTGAATTTAGCAAAGAAATAGAGATAATCATGATTATACCTTTATTTTTACAGGAAGAGATGATGTAACTAGAGTATGTGTCT
ACAGGAGTAATAATGGTTTCCAAAGAGTATTTTTTAAAGGAACAAAACGAGCATGAATTAACTCTTCAATATAAGCTATGAAGTAATAGT
TGGTTGTGAATTAAAGTGGCACCAGCTAGCACCTCTGTGTTTTAAGGGTCTTTCAATGTTTCTAGAATAAGCCCTTATTTTCAAGGGTTC
ATAACAGGCATAAAATCTCTTCTCCTGGCAAAAGCTGCTATGAAAAGCCTCAGCTTGGGAAGATAGATTTTTTTCCCCCCAATTACAAAA
TCTAAGTATTTTGGCCCTTCAATTTGGAGGAGGGCAAAAGTTGGAAGTAAGAAGTTTTATTTTAAGTACTTTCAGTGCTCAAAAAAATGC
AATCACTGTGTTGTATATAATAGTTCATAGGTTGATCACTCATAATAATTGACTCTAAGGCTTTTATTAAGAAAACAGCAGAAAGATTAA
ATCTTGAATTAAGTCTGGGGGGAAATGGCCACTGCAGATGGAGTTTTAGAGTAGTAATGAAATTCTACCTAGAATGCAAAATTGGGTATA
TGAATTACATAGCATGTTGTTGGGATTTTTTTTAATGTGCAGAAGATCAAAGCTACTTGGAAGGAGTGCCTATAATTTGCCAGTAGCCAC
AGATTAAGATTATATCTTATATATCAGCAGATTAGCTTTAGCTTAGGGGGAGGGTGGGAAAGTTTGGGGGGGGGGTTGTGAAGATTTAGG
GGGACCTTGATAGAGAACTTTATAAACTTCTTTCTCTTTAATAAAGACTTGTCTTACACCGTGCTGCCATTAAAGGCAGCTGTTCTAGAG
TTTCAGTCACCTAAGTACACCCACAAAACAATATGAATATGGAGATCTTCCTTTACCCCTCAACTTTAATTTGCCCAGTTATACCTCAGT
GTTGTAGCAGTACTGTGATACCTGGCACAGTGCTTTGATCTTACGATGCCCTCTGTACTGACCTGAAGGAGACCTAAGAGTCCTTTCCCT
TTTTGAGTTTGAATCATAGCCTTGATGTGGTCTCTTGTTTTATGTCCTTGTTCCTAATGTAAAAGTGCTTAACTGCTTCTTGGTTGTATT
GGGTAGCATTGGGATAAGATTTTAACTGGGTATTCTTGAATTGCTTTTACAATAAACCAATTTTATAATCTTTAAATTTATCAACTTTTT
ACATTTGTGTTATTTTCAGTCAGGGCTTCTTAGATCTACTTATGGTTGATGGAGCACATTGATTTGGAGTTTCAGATCTTCCAAAGCACT
ATTTGTTGTAATAACTTTTCTAAATGTAGTGCCTTTAAAGGAAAAATGAACACAGGGAAGTGACTTTGCTACAAATAATGTTGCTGTGTT
AAGTATTCATATTAAATACATGCCTTCTATATGGAACATGGCAGAAAGACTGAAAAATAACAGTAATTAATTGTGTAATTCAGAATTCAT
ACCAATCAGTGTTGAAACTCAAACATTGCAAAAGTGGGTGGCAATATTCAGTGCTTAACACTTTTCTAGCGTTGGTACATCTGAGAAATG
AGTGCTCAGGTGGATTTTATCCTCGCAAGCATGTTGTTATAAGAATTGTGGGTGTGCCTATCATAACAATTGTTTTCTGTATCTTGAAAA
AGTATTCTCCACATTTTAAATGTTTTATATTAGAGAATTCTTTAATGCACACTTGTCAAATATATATATATAGTACCAATGTTACCTTTT
TATTTTTTGTTTTAGATGTAAGAGCATGCTCATATGTTAGGTACTTACATAAATTGTTACATTATTTTTTCTTATGTAATACCTTTTTGT

>In-frame_ENST00000351960_ENST00000282441_TCGA-GN-A4U7-06A_NUMA1_chr11_71746948_-_YAP1_chr11_102094353_length(amino acids)=180AA_start in transcript=154_stop in transcript=696
MSGITKMTLHATRGAALLSWELALRSQLPTLEQDGGTQNPVSSPGMSQELRTMTTNSSDPFLNSGTYHSRDESTDSGLSMSSYSVPRTPD
DFLNSVDEMDTGDTINQSTLPSQQNRFPDYLEAIPGTNVDLGTLEGDGMNIEGEELMPSLQEALSSDILNDMESVLAATKLDKESFLTWL

--------------------------------------------------------------
>In-frame_ENST00000351960_ENST00000537274_TCGA-GN-A4U7-06A_NUMA1_chr11_71746948_-_YAP1_chr11_102094353_length(transcript)=4180nt_BP=214nt
GTGCTGGAGAGGCCGCTGCGAGCGGAAGGCCTCCTCCATAACCGAGTCCGAAAGGGCAGAATCTATGGGGGTGGAAACTAATTCTAAGCC
AGACTGCTGGAGATCACCCTGTTCTAGTGTGTGGAGGCTTCCACCAGGAGGCGCATTGGAGTGACTGTCTGGCATCACCAAGATGACACT
CCACGCCACCCGGGGGGCTGCACTCCTCTCTTGGGAGTTAGCCCTGCGTAGCCAGTTACCAACACTGGAGCAGGATGGTGGGACTCAAAA
TCCAGTGTCTTCTCCCGGGATGTCTCAGGAATTGAGAACAATGACGACCAATAGCTCAGATCCTTTCCTTAACAGTGGCACCTATCACTC
TCGAGATGAGAGTACAGACAGTGGACTAAGCATGAGCAGCTACAGTGTCCCTCGAACCCCAGATGACTTCCTGAACAGTGTGGATGAGAT
GGATACAGGTGATACTATCAACCAAAGCACCCTGCCCTCACAGCAGAACCGTTTCCCAGACTACCTTGAAGCCATTCCTGGGACAAATGT
GGACCTTGGAACACTGGAAGGAGATGGAATGAACATAGAAGGAGAGGAGCTGATGCCAAGTCTGCAGGAAGCTTTGAGTTCTGACATCCT
TAATGACATGGAGTCTGTTTTGGCTGCCACCAAGCTAGATAAAGAAAGCTTTCTTACATGGTTATAGAGCCCTCAGGCAGACTGAATTCT
AAATCTGTGAAGGATCTAAGGAGACACATGCACCGGAAATTTCCATAAGCCAGTTGCAGTTTTCAGGCTAATACAGAAAAAGATGAACAA
ACGTCCAGCAAGATACTTTAATCCTCTATTTTGCTCTTCCTTGTCCATTGCTGCTGTTAATGTATTGCTGACCTCTTTCACAGTTGGCTC
TAAAGAATCAAAAGAAAAAAACTTTTTATTTCTTTTGCTATTAAAACTACTGTTCATTTTGGGGGCTGGGGGAAGTGAGCCTGTTTGGAT
GATGGATGCCATTCCTTTTGCCCAGTTAAATGTTCACCAATCATTTTAACTAAATACTCAGACTTAGAAGTCAGATGCTTCATGTCACAG
CATTTAGTTTGTTCAACAGTTGTTTCTTCAGCTTCCTTTGTCCAGTGGAAAAACATGATTTACTGGTCTGACAAGCCAAAAATGTTATAT
CTGATATTAAATACTTAATGCTGATTTGAAGAGATAGCTGAAACCAAGGCTGAAGACTGTTTTACTTTCAGTATTTTCTTTTCCTCCTAG
TGCTATCATTAGTCACATAATGACCTTGATTTTATTTTAGGAGCTTATAAGGCATGAGACAATTTCCATATAAATATATTAATTATTGCC
ACATACTCTAATATAGATTTTGGTGGATAATTTTGTGGGTGTGCATTTTGTTCTGTTTTGTTGGGTTTTTTGTTTTTTTTGTTTTTGGCA
GGGTCGGTGGGGGGGTTGGTTGGTTGGTTGGTTTTGTCGGAACCTAGGCAAATGACCATATTAGTGAATCTGTTAATAGTTGTAGCTTGG
GATGGTTATTGTAGTTGTTTTGGTAAAATCTTCATTTCCTGGTTTTTTTTACCACCTTATTTAAATCTCGATTATCTGCTCTCTCTTTTA
TATACATACACACACCCAAACATAACATTTATAATAGTGTGGTAGTGGAATGTATCCTTTTTTAGGTTTCCCTGCTTTCCAGTTAATTTT
TAAAATGGTAGCGCTTTGTATGCATTTAGAATACATGACTAGTAGTTTATATTTCACTGGTAGTTTAAATCTGGTTGGGGCAGTCTGCAG
ATGTTTGAAGTAGTTTAGTGTTCTAGAAAGAGCTATTACTGTGGATAGTGCCTAGGGGAGTGCTCCACGCCCTCTGGGCATACGGTAGAT
ATTATCTGATGAATTGGAAAGGAGCAAACCAGAAATGGCTTTATTTTCTCCCTTGGACTAATTTTTAAGTCTCGATTGGAATTCAGTGAG
TAGGTTCATAATGTGCATGACAGAAATAAGCTTTATAGTGGTTTACCTTCATTTAGCTTTGGAAGTTTTCTTTGCCTTAGTTTTGGAAGT
AAATTCTAGTTTGTAGTTCTCATTTGTAATGAACACATTAACGACTAGATTAAAATATTGCCTTCAAGATTGTTCTTACTTACAAGACTT
GCTCCTACTTCTATGCTGAAAATTGACCCTGGATAGAATACTATAAGGTTTTGAGTTAGCTGGAAAAGTGATCAGATTAATAAATGTATA
TTGGTAGTTGAATTTAGCAAAGAAATAGAGATAATCATGATTATACCTTTATTTTTACAGGAAGAGATGATGTAACTAGAGTATGTGTCT
ACAGGAGTAATAATGGTTTCCAAAGAGTATTTTTTAAAGGAACAAAACGAGCATGAATTAACTCTTCAATATAAGCTATGAAGTAATAGT
TGGTTGTGAATTAAAGTGGCACCAGCTAGCACCTCTGTGTTTTAAGGGTCTTTCAATGTTTCTAGAATAAGCCCTTATTTTCAAGGGTTC
ATAACAGGCATAAAATCTCTTCTCCTGGCAAAAGCTGCTATGAAAAGCCTCAGCTTGGGAAGATAGATTTTTTTCCCCCCAATTACAAAA
TCTAAGTATTTTGGCCCTTCAATTTGGAGGAGGGCAAAAGTTGGAAGTAAGAAGTTTTATTTTAAGTACTTTCAGTGCTCAAAAAAATGC
AATCACTGTGTTGTATATAATAGTTCATAGGTTGATCACTCATAATAATTGACTCTAAGGCTTTTATTAAGAAAACAGCAGAAAGATTAA
ATCTTGAATTAAGTCTGGGGGGAAATGGCCACTGCAGATGGAGTTTTAGAGTAGTAATGAAATTCTACCTAGAATGCAAAATTGGGTATA
TGAATTACATAGCATGTTGTTGGGATTTTTTTTAATGTGCAGAAGATCAAAGCTACTTGGAAGGAGTGCCTATAATTTGCCAGTAGCCAC
AGATTAAGATTATATCTTATATATCAGCAGATTAGCTTTAGCTTAGGGGGAGGGTGGGAAAGTTTGGGGGGGGGGTTGTGAAGATTTAGG
GGGACCTTGATAGAGAACTTTATAAACTTCTTTCTCTTTAATAAAGACTTGTCTTACACCGTGCTGCCATTAAAGGCAGCTGTTCTAGAG
TTTCAGTCACCTAAGTACACCCACAAAACAATATGAATATGGAGATCTTCCTTTACCCCTCAACTTTAATTTGCCCAGTTATACCTCAGT
GTTGTAGCAGTACTGTGATACCTGGCACAGTGCTTTGATCTTACGATGCCCTCTGTACTGACCTGAAGGAGACCTAAGAGTCCTTTCCCT
TTTTGAGTTTGAATCATAGCCTTGATGTGGTCTCTTGTTTTATGTCCTTGTTCCTAATGTAAAAGTGCTTAACTGCTTCTTGGTTGTATT
GGGTAGCATTGGGATAAGATTTTAACTGGGTATTCTTGAATTGCTTTTACAATAAACCAATTTTATAATCTTTAAATTTATCAACTTTTT
ACATTTGTGTTATTTTCAGTCAGGGCTTCTTAGATCTACTTATGGTTGATGGAGCACATTGATTTGGAGTTTCAGATCTTCCAAAGCACT
ATTTGTTGTAATAACTTTTCTAAATGTAGTGCCTTTAAAGGAAAAATGAACACAGGGAAGTGACTTTGCTACAAATAATGTTGCTGTGTT
AAGTATTCATATTAAATACATGCCTTCTATATGGAACATGGCAGAAAGACTGAAAAATAACAGTAATTAATTGTGTAATTCAGAATTCAT
ACCAATCAGTGTTGAAACTCAAACATTGCAAAAGTGGGTGGCAATATTCAGTGCTTAACACTTTTCTAGCGTTGGTACATCTGAGAAATG
AGTGCTCAGGTGGATTTTATCCTCGCAAGCATGTTGTTATAAGAATTGTGGGTGTGCCTATCATAACAATTGTTTTCTGTATCTTGAAAA
AGTATTCTCCACATTTTAAATGTTTTATATTAGAGAATTCTTTAATGCACACTTGTCAAATATATATATATAGTACCAATGTTACCTTTT
TATTTTTTGTTTTAGATGTAAGAGCATGCTCATATGTTAGGTACTTACATAAATTGTTACATTATTTTTTCTTATGTAATACCTTTTTGT

>In-frame_ENST00000351960_ENST00000537274_TCGA-GN-A4U7-06A_NUMA1_chr11_71746948_-_YAP1_chr11_102094353_length(amino acids)=180AA_start in transcript=154_stop in transcript=696
MSGITKMTLHATRGAALLSWELALRSQLPTLEQDGGTQNPVSSPGMSQELRTMTTNSSDPFLNSGTYHSRDESTDSGLSMSSYSVPRTPD
DFLNSVDEMDTGDTINQSTLPSQQNRFPDYLEAIPGTNVDLGTLEGDGMNIEGEELMPSLQEALSSDILNDMESVLAATKLDKESFLTWL

--------------------------------------------------------------
>In-frame_ENST00000351960_ENST00000345877_TCGA-GN-A4U7-06A_NUMA1_chr11_71746948_-_YAP1_chr11_102094353_length(transcript)=4180nt_BP=214nt
GTGCTGGAGAGGCCGCTGCGAGCGGAAGGCCTCCTCCATAACCGAGTCCGAAAGGGCAGAATCTATGGGGGTGGAAACTAATTCTAAGCC
AGACTGCTGGAGATCACCCTGTTCTAGTGTGTGGAGGCTTCCACCAGGAGGCGCATTGGAGTGACTGTCTGGCATCACCAAGATGACACT
CCACGCCACCCGGGGGGCTGCACTCCTCTCTTGGGAGTTAGCCCTGCGTAGCCAGTTACCAACACTGGAGCAGGATGGTGGGACTCAAAA
TCCAGTGTCTTCTCCCGGGATGTCTCAGGAATTGAGAACAATGACGACCAATAGCTCAGATCCTTTCCTTAACAGTGGCACCTATCACTC
TCGAGATGAGAGTACAGACAGTGGACTAAGCATGAGCAGCTACAGTGTCCCTCGAACCCCAGATGACTTCCTGAACAGTGTGGATGAGAT
GGATACAGGTGATACTATCAACCAAAGCACCCTGCCCTCACAGCAGAACCGTTTCCCAGACTACCTTGAAGCCATTCCTGGGACAAATGT
GGACCTTGGAACACTGGAAGGAGATGGAATGAACATAGAAGGAGAGGAGCTGATGCCAAGTCTGCAGGAAGCTTTGAGTTCTGACATCCT
TAATGACATGGAGTCTGTTTTGGCTGCCACCAAGCTAGATAAAGAAAGCTTTCTTACATGGTTATAGAGCCCTCAGGCAGACTGAATTCT
AAATCTGTGAAGGATCTAAGGAGACACATGCACCGGAAATTTCCATAAGCCAGTTGCAGTTTTCAGGCTAATACAGAAAAAGATGAACAA
ACGTCCAGCAAGATACTTTAATCCTCTATTTTGCTCTTCCTTGTCCATTGCTGCTGTTAATGTATTGCTGACCTCTTTCACAGTTGGCTC
TAAAGAATCAAAAGAAAAAAACTTTTTATTTCTTTTGCTATTAAAACTACTGTTCATTTTGGGGGCTGGGGGAAGTGAGCCTGTTTGGAT
GATGGATGCCATTCCTTTTGCCCAGTTAAATGTTCACCAATCATTTTAACTAAATACTCAGACTTAGAAGTCAGATGCTTCATGTCACAG
CATTTAGTTTGTTCAACAGTTGTTTCTTCAGCTTCCTTTGTCCAGTGGAAAAACATGATTTACTGGTCTGACAAGCCAAAAATGTTATAT
CTGATATTAAATACTTAATGCTGATTTGAAGAGATAGCTGAAACCAAGGCTGAAGACTGTTTTACTTTCAGTATTTTCTTTTCCTCCTAG
TGCTATCATTAGTCACATAATGACCTTGATTTTATTTTAGGAGCTTATAAGGCATGAGACAATTTCCATATAAATATATTAATTATTGCC
ACATACTCTAATATAGATTTTGGTGGATAATTTTGTGGGTGTGCATTTTGTTCTGTTTTGTTGGGTTTTTTGTTTTTTTTGTTTTTGGCA
GGGTCGGTGGGGGGGTTGGTTGGTTGGTTGGTTTTGTCGGAACCTAGGCAAATGACCATATTAGTGAATCTGTTAATAGTTGTAGCTTGG
GATGGTTATTGTAGTTGTTTTGGTAAAATCTTCATTTCCTGGTTTTTTTTACCACCTTATTTAAATCTCGATTATCTGCTCTCTCTTTTA
TATACATACACACACCCAAACATAACATTTATAATAGTGTGGTAGTGGAATGTATCCTTTTTTAGGTTTCCCTGCTTTCCAGTTAATTTT
TAAAATGGTAGCGCTTTGTATGCATTTAGAATACATGACTAGTAGTTTATATTTCACTGGTAGTTTAAATCTGGTTGGGGCAGTCTGCAG
ATGTTTGAAGTAGTTTAGTGTTCTAGAAAGAGCTATTACTGTGGATAGTGCCTAGGGGAGTGCTCCACGCCCTCTGGGCATACGGTAGAT
ATTATCTGATGAATTGGAAAGGAGCAAACCAGAAATGGCTTTATTTTCTCCCTTGGACTAATTTTTAAGTCTCGATTGGAATTCAGTGAG
TAGGTTCATAATGTGCATGACAGAAATAAGCTTTATAGTGGTTTACCTTCATTTAGCTTTGGAAGTTTTCTTTGCCTTAGTTTTGGAAGT
AAATTCTAGTTTGTAGTTCTCATTTGTAATGAACACATTAACGACTAGATTAAAATATTGCCTTCAAGATTGTTCTTACTTACAAGACTT
GCTCCTACTTCTATGCTGAAAATTGACCCTGGATAGAATACTATAAGGTTTTGAGTTAGCTGGAAAAGTGATCAGATTAATAAATGTATA
TTGGTAGTTGAATTTAGCAAAGAAATAGAGATAATCATGATTATACCTTTATTTTTACAGGAAGAGATGATGTAACTAGAGTATGTGTCT
ACAGGAGTAATAATGGTTTCCAAAGAGTATTTTTTAAAGGAACAAAACGAGCATGAATTAACTCTTCAATATAAGCTATGAAGTAATAGT
TGGTTGTGAATTAAAGTGGCACCAGCTAGCACCTCTGTGTTTTAAGGGTCTTTCAATGTTTCTAGAATAAGCCCTTATTTTCAAGGGTTC
ATAACAGGCATAAAATCTCTTCTCCTGGCAAAAGCTGCTATGAAAAGCCTCAGCTTGGGAAGATAGATTTTTTTCCCCCCAATTACAAAA
TCTAAGTATTTTGGCCCTTCAATTTGGAGGAGGGCAAAAGTTGGAAGTAAGAAGTTTTATTTTAAGTACTTTCAGTGCTCAAAAAAATGC
AATCACTGTGTTGTATATAATAGTTCATAGGTTGATCACTCATAATAATTGACTCTAAGGCTTTTATTAAGAAAACAGCAGAAAGATTAA
ATCTTGAATTAAGTCTGGGGGGAAATGGCCACTGCAGATGGAGTTTTAGAGTAGTAATGAAATTCTACCTAGAATGCAAAATTGGGTATA
TGAATTACATAGCATGTTGTTGGGATTTTTTTTAATGTGCAGAAGATCAAAGCTACTTGGAAGGAGTGCCTATAATTTGCCAGTAGCCAC
AGATTAAGATTATATCTTATATATCAGCAGATTAGCTTTAGCTTAGGGGGAGGGTGGGAAAGTTTGGGGGGGGGGTTGTGAAGATTTAGG
GGGACCTTGATAGAGAACTTTATAAACTTCTTTCTCTTTAATAAAGACTTGTCTTACACCGTGCTGCCATTAAAGGCAGCTGTTCTAGAG
TTTCAGTCACCTAAGTACACCCACAAAACAATATGAATATGGAGATCTTCCTTTACCCCTCAACTTTAATTTGCCCAGTTATACCTCAGT
GTTGTAGCAGTACTGTGATACCTGGCACAGTGCTTTGATCTTACGATGCCCTCTGTACTGACCTGAAGGAGACCTAAGAGTCCTTTCCCT
TTTTGAGTTTGAATCATAGCCTTGATGTGGTCTCTTGTTTTATGTCCTTGTTCCTAATGTAAAAGTGCTTAACTGCTTCTTGGTTGTATT
GGGTAGCATTGGGATAAGATTTTAACTGGGTATTCTTGAATTGCTTTTACAATAAACCAATTTTATAATCTTTAAATTTATCAACTTTTT
ACATTTGTGTTATTTTCAGTCAGGGCTTCTTAGATCTACTTATGGTTGATGGAGCACATTGATTTGGAGTTTCAGATCTTCCAAAGCACT
ATTTGTTGTAATAACTTTTCTAAATGTAGTGCCTTTAAAGGAAAAATGAACACAGGGAAGTGACTTTGCTACAAATAATGTTGCTGTGTT
AAGTATTCATATTAAATACATGCCTTCTATATGGAACATGGCAGAAAGACTGAAAAATAACAGTAATTAATTGTGTAATTCAGAATTCAT
ACCAATCAGTGTTGAAACTCAAACATTGCAAAAGTGGGTGGCAATATTCAGTGCTTAACACTTTTCTAGCGTTGGTACATCTGAGAAATG
AGTGCTCAGGTGGATTTTATCCTCGCAAGCATGTTGTTATAAGAATTGTGGGTGTGCCTATCATAACAATTGTTTTCTGTATCTTGAAAA
AGTATTCTCCACATTTTAAATGTTTTATATTAGAGAATTCTTTAATGCACACTTGTCAAATATATATATATAGTACCAATGTTACCTTTT
TATTTTTTGTTTTAGATGTAAGAGCATGCTCATATGTTAGGTACTTACATAAATTGTTACATTATTTTTTCTTATGTAATACCTTTTTGT

>In-frame_ENST00000351960_ENST00000345877_TCGA-GN-A4U7-06A_NUMA1_chr11_71746948_-_YAP1_chr11_102094353_length(amino acids)=180AA_start in transcript=154_stop in transcript=696
MSGITKMTLHATRGAALLSWELALRSQLPTLEQDGGTQNPVSSPGMSQELRTMTTNSSDPFLNSGTYHSRDESTDSGLSMSSYSVPRTPD
DFLNSVDEMDTGDTINQSTLPSQQNRFPDYLEAIPGTNVDLGTLEGDGMNIEGEELMPSLQEALSSDILNDMESVLAATKLDKESFLTWL

--------------------------------------------------------------
>In-frame_ENST00000351960_ENST00000531439_TCGA-GN-A4U7-06A_NUMA1_chr11_71746948_-_YAP1_chr11_102094353_length(transcript)=720nt_BP=214nt
GTGCTGGAGAGGCCGCTGCGAGCGGAAGGCCTCCTCCATAACCGAGTCCGAAAGGGCAGAATCTATGGGGGTGGAAACTAATTCTAAGCC
AGACTGCTGGAGATCACCCTGTTCTAGTGTGTGGAGGCTTCCACCAGGAGGCGCATTGGAGTGACTGTCTGGCATCACCAAGATGACACT
CCACGCCACCCGGGGGGCTGCACTCCTCTCTTGGGAGTTAGCCCTGCGTAGCCAGTTACCAACACTGGAGCAGGATGGTGGGACTCAAAA
TCCAGTGTCTTCTCCCGGGATGTCTCAGGAATTGAGAACAATGACGACCAATAGCTCAGATCCTTTCCTTAACAGTGGCACCTATCACTC
TCGAGATGAGAGTACAGACAGTGGACTAAGCATGAGCAGCTACAGTGTCCCTCGAACCCCAGATGACTTCCTGAACAGTGTGGATGAGAT
GGATACAGGTGATACTATCAACCAAAGCACCCTGCCCTCACAGCAGAACCGTTTCCCAGACTACCTTGAAGCCATTCCTGGGACAAATGT
GGACCTTGGAACACTGGAAGGAGATGGAATGAACATAGAAGGAGAGGAGCTGATGCCAAGTCTGCAGGAAGCTTTGAGTTCTGACATCCT
TAATGACATGGAGTCTGTTTTGGCTGCCACCAAGCTAGATAAAGAAAGCTTTCTTACATGGTTATAGAGCCCTCAGGCAGACTGAATTCT

>In-frame_ENST00000351960_ENST00000531439_TCGA-GN-A4U7-06A_NUMA1_chr11_71746948_-_YAP1_chr11_102094353_length(amino acids)=180AA_start in transcript=154_stop in transcript=696
MSGITKMTLHATRGAALLSWELALRSQLPTLEQDGGTQNPVSSPGMSQELRTMTTNSSDPFLNSGTYHSRDESTDSGLSMSSYSVPRTPD
DFLNSVDEMDTGDTINQSTLPSQQNRFPDYLEAIPGTNVDLGTLEGDGMNIEGEELMPSLQEALSSDILNDMESVLAATKLDKESFLTWL

--------------------------------------------------------------
>In-frame_ENST00000351960_ENST00000524575_TCGA-GN-A4U7-06A_NUMA1_chr11_71746948_-_YAP1_chr11_102094353_length(transcript)=909nt_BP=214nt
GTGCTGGAGAGGCCGCTGCGAGCGGAAGGCCTCCTCCATAACCGAGTCCGAAAGGGCAGAATCTATGGGGGTGGAAACTAATTCTAAGCC
AGACTGCTGGAGATCACCCTGTTCTAGTGTGTGGAGGCTTCCACCAGGAGGCGCATTGGAGTGACTGTCTGGCATCACCAAGATGACACT
CCACGCCACCCGGGGGGCTGCACTCCTCTCTTGGGAGTTAGCCCTGCGTAGCCAGTTACCAACACTGGAGCAGGATGGTGGGACTCAAAA
TCCAGTGTCTTCTCCCGGGATGTCTCAGGAATTGAGAACAATGACGACCAATAGCTCAGATCCTTTCCTTAACAGTGGCACCTATCACTC
TCGAGATGAGAGTACAGACAGTGGACTAAGCATGAGCAGCTACAGTGTCCCTCGAACCCCAGATGACTTCCTGAACAGTGTGGATGAGAT
GGATACAGGTGATACTATCAACCAAAGCACCCTGCCCTCACAGCAGAACCGTTTCCCAGACTACCTTGAAGCCATTCCTGGGACAAATGT
GGACCTTGGAACACTGGAAGGAGATGGAATGAACATAGAAGGAGAGGAGCTGATGCCAAGTCTGCAGGAAGCTTTGAGTTCTGACATCCT
TAATGACATGGAGTCTGTTTTGGCTGCCACCAAGCTAGATAAAGAAAGCTTTCTTACATGGTTATAGAGCCCTCAGGCAGACTGAATTCT
AAATCTGTGAAGGATCTAAGGAGACACATGCACCGGAAATTTCCATAAGCCAGTTGCAGTTTTCAGGCTAATACAGAAAAAGATGAACAA
ACGTCCAGCAAGATACTTTAATCCTCTATTTTGCTCTTCCTTGTCCATTGCTGCTGTTAATGTATTGCTGACCTCTTTCACAGTTGGCTC

>In-frame_ENST00000351960_ENST00000524575_TCGA-GN-A4U7-06A_NUMA1_chr11_71746948_-_YAP1_chr11_102094353_length(amino acids)=180AA_start in transcript=154_stop in transcript=696
MSGITKMTLHATRGAALLSWELALRSQLPTLEQDGGTQNPVSSPGMSQELRTMTTNSSDPFLNSGTYHSRDESTDSGLSMSSYSVPRTPD
DFLNSVDEMDTGDTINQSTLPSQQNRFPDYLEAIPGTNVDLGTLEGDGMNIEGEELMPSLQEALSSDILNDMESVLAATKLDKESFLTWL

--------------------------------------------------------------
>In-frame_ENST00000393695_ENST00000526343_TCGA-GN-A4U7-06A_NUMA1_chr11_71746948_-_YAP1_chr11_102094353_length(transcript)=1509nt_BP=374nt
AAGTACAGGCCGGGGTCCGGAAGCGGTGATACCCCTTCTCTTTCCCAGTGGCCCTCAAACTTCCTTTTCCCGGGTCCTTAAGCGGGCCCC
GCCGACAGAGGCCAATCAGAGGGCAGCGCGAGGGGGCGGGGCCATAGTTTAAACTAATTGTGCGCTCACAGCGCTGGCGCGAGCCCACGA
AGAGGTACGATTCCGGAGAATCGCGAGGCAGAGCGGGAGCGCGCAGCCAGGTGGAAACTAATTCTAAGCCAGACTGCTGGAGATCACCCT
GTTCTAGTGTGTGGAGGCTTCCACCAGGAGGCGCATTGGAGTGACTGTCTGGCATCACCAAGATGACACTCCACGCCACCCGGGGGGCTG
CACTCCTCTCTTGGGAGTTAGCCCTGCGTAGCCAGTTACCAACACTGGAGCAGGATGGTGGGACTCAAAATCCAGTGTCTTCTCCCGGGA
TGTCTCAGGAATTGAGAACAATGACGACCAATAGCTCAGATCCTTTCCTTAACAGTGGCACCTATCACTCTCGAGATGAGAGTACAGACA
GTGGACTAAGCATGAGCAGCTACAGTGTCCCTCGAACCCCAGATGACTTCCTGAACAGTGTGGATGAGATGGATACAGGTGATACTATCA
ACCAAAGCACCCTGCCCTCACAGCAGAACCGTTTCCCAGACTACCTTGAAGCCATTCCTGGGACAAATGTGGACCTTGGAACACTGGAAG
GAGATGGAATGAACATAGAAGGAGAGGAGCTGATGCCAAGTCTGCAGGAAGCTTTGAGTTCTGACATCCTTAATGACATGGAGTCTGTTT
TGGCTGCCACCAAGCTAGATAAAGAAAGCTTTCTTACATGGTTATAGAGCCCTCAGGCAGACTGAATTCTAAATCTGTGAAGGATCTAAG
GAGACACATGCACCGGAAATTTCCATAAGCCAGTTGCAGTTTTCAGGCTAATACAGAAAAAGATGAACAAACGTCCAGCAAGATACTTTA
ATCCTCTATTTTGCTCTTCCTTGTCCATTGCTGCTGTTAATGTATTGCTGACCTCTTTCACAGTTGGCTCTAAAGAATCAAAAGAAAAAA
ACTTTTTATTTCTTTTGCTATTAAAACTACTGTTCATTTTGGGGGCTGGGGGAAGTGAGCCTGTTTGGATGATGGATGCCATTCCTTTTG
CCCAGTTAAATGTTCACCAATCATTTTAACTAAATACTCAGACTTAGAAGTCAGATGCTTCATGTCACAGCATTTAGTTTGTTCAACAGT
TGTTTCTTCAGCTTCCTTTGTCCAGTGGAAAAACATGATTTACTGGTCTGACAAGCCAAAAATGTTATATCTGATATTAAATACTTAATG
CTGATTTGAAGAGATAGCTGAAACCAAGGCTGAAGACTGTTTTACTTTCAGTATTTTCTTTTCCTCCTAGTGCTATCATTAGTCACATAA

>In-frame_ENST00000393695_ENST00000526343_TCGA-GN-A4U7-06A_NUMA1_chr11_71746948_-_YAP1_chr11_102094353_length(amino acids)=180AA_start in transcript=314_stop in transcript=856
MSGITKMTLHATRGAALLSWELALRSQLPTLEQDGGTQNPVSSPGMSQELRTMTTNSSDPFLNSGTYHSRDESTDSGLSMSSYSVPRTPD
DFLNSVDEMDTGDTINQSTLPSQQNRFPDYLEAIPGTNVDLGTLEGDGMNIEGEELMPSLQEALSSDILNDMESVLAATKLDKESFLTWL

--------------------------------------------------------------
>In-frame_ENST00000393695_ENST00000282441_TCGA-GN-A4U7-06A_NUMA1_chr11_71746948_-_YAP1_chr11_102094353_length(transcript)=4340nt_BP=374nt
AAGTACAGGCCGGGGTCCGGAAGCGGTGATACCCCTTCTCTTTCCCAGTGGCCCTCAAACTTCCTTTTCCCGGGTCCTTAAGCGGGCCCC
GCCGACAGAGGCCAATCAGAGGGCAGCGCGAGGGGGCGGGGCCATAGTTTAAACTAATTGTGCGCTCACAGCGCTGGCGCGAGCCCACGA
AGAGGTACGATTCCGGAGAATCGCGAGGCAGAGCGGGAGCGCGCAGCCAGGTGGAAACTAATTCTAAGCCAGACTGCTGGAGATCACCCT
GTTCTAGTGTGTGGAGGCTTCCACCAGGAGGCGCATTGGAGTGACTGTCTGGCATCACCAAGATGACACTCCACGCCACCCGGGGGGCTG
CACTCCTCTCTTGGGAGTTAGCCCTGCGTAGCCAGTTACCAACACTGGAGCAGGATGGTGGGACTCAAAATCCAGTGTCTTCTCCCGGGA
TGTCTCAGGAATTGAGAACAATGACGACCAATAGCTCAGATCCTTTCCTTAACAGTGGCACCTATCACTCTCGAGATGAGAGTACAGACA
GTGGACTAAGCATGAGCAGCTACAGTGTCCCTCGAACCCCAGATGACTTCCTGAACAGTGTGGATGAGATGGATACAGGTGATACTATCA
ACCAAAGCACCCTGCCCTCACAGCAGAACCGTTTCCCAGACTACCTTGAAGCCATTCCTGGGACAAATGTGGACCTTGGAACACTGGAAG
GAGATGGAATGAACATAGAAGGAGAGGAGCTGATGCCAAGTCTGCAGGAAGCTTTGAGTTCTGACATCCTTAATGACATGGAGTCTGTTT
TGGCTGCCACCAAGCTAGATAAAGAAAGCTTTCTTACATGGTTATAGAGCCCTCAGGCAGACTGAATTCTAAATCTGTGAAGGATCTAAG
GAGACACATGCACCGGAAATTTCCATAAGCCAGTTGCAGTTTTCAGGCTAATACAGAAAAAGATGAACAAACGTCCAGCAAGATACTTTA
ATCCTCTATTTTGCTCTTCCTTGTCCATTGCTGCTGTTAATGTATTGCTGACCTCTTTCACAGTTGGCTCTAAAGAATCAAAAGAAAAAA
ACTTTTTATTTCTTTTGCTATTAAAACTACTGTTCATTTTGGGGGCTGGGGGAAGTGAGCCTGTTTGGATGATGGATGCCATTCCTTTTG
CCCAGTTAAATGTTCACCAATCATTTTAACTAAATACTCAGACTTAGAAGTCAGATGCTTCATGTCACAGCATTTAGTTTGTTCAACAGT
TGTTTCTTCAGCTTCCTTTGTCCAGTGGAAAAACATGATTTACTGGTCTGACAAGCCAAAAATGTTATATCTGATATTAAATACTTAATG
CTGATTTGAAGAGATAGCTGAAACCAAGGCTGAAGACTGTTTTACTTTCAGTATTTTCTTTTCCTCCTAGTGCTATCATTAGTCACATAA
TGACCTTGATTTTATTTTAGGAGCTTATAAGGCATGAGACAATTTCCATATAAATATATTAATTATTGCCACATACTCTAATATAGATTT
TGGTGGATAATTTTGTGGGTGTGCATTTTGTTCTGTTTTGTTGGGTTTTTTGTTTTTTTTGTTTTTGGCAGGGTCGGTGGGGGGGTTGGT
TGGTTGGTTGGTTTTGTCGGAACCTAGGCAAATGACCATATTAGTGAATCTGTTAATAGTTGTAGCTTGGGATGGTTATTGTAGTTGTTT
TGGTAAAATCTTCATTTCCTGGTTTTTTTTACCACCTTATTTAAATCTCGATTATCTGCTCTCTCTTTTATATACATACACACACCCAAA
CATAACATTTATAATAGTGTGGTAGTGGAATGTATCCTTTTTTAGGTTTCCCTGCTTTCCAGTTAATTTTTAAAATGGTAGCGCTTTGTA
TGCATTTAGAATACATGACTAGTAGTTTATATTTCACTGGTAGTTTAAATCTGGTTGGGGCAGTCTGCAGATGTTTGAAGTAGTTTAGTG
TTCTAGAAAGAGCTATTACTGTGGATAGTGCCTAGGGGAGTGCTCCACGCCCTCTGGGCATACGGTAGATATTATCTGATGAATTGGAAA
GGAGCAAACCAGAAATGGCTTTATTTTCTCCCTTGGACTAATTTTTAAGTCTCGATTGGAATTCAGTGAGTAGGTTCATAATGTGCATGA
CAGAAATAAGCTTTATAGTGGTTTACCTTCATTTAGCTTTGGAAGTTTTCTTTGCCTTAGTTTTGGAAGTAAATTCTAGTTTGTAGTTCT
CATTTGTAATGAACACATTAACGACTAGATTAAAATATTGCCTTCAAGATTGTTCTTACTTACAAGACTTGCTCCTACTTCTATGCTGAA
AATTGACCCTGGATAGAATACTATAAGGTTTTGAGTTAGCTGGAAAAGTGATCAGATTAATAAATGTATATTGGTAGTTGAATTTAGCAA
AGAAATAGAGATAATCATGATTATACCTTTATTTTTACAGGAAGAGATGATGTAACTAGAGTATGTGTCTACAGGAGTAATAATGGTTTC
CAAAGAGTATTTTTTAAAGGAACAAAACGAGCATGAATTAACTCTTCAATATAAGCTATGAAGTAATAGTTGGTTGTGAATTAAAGTGGC
ACCAGCTAGCACCTCTGTGTTTTAAGGGTCTTTCAATGTTTCTAGAATAAGCCCTTATTTTCAAGGGTTCATAACAGGCATAAAATCTCT
TCTCCTGGCAAAAGCTGCTATGAAAAGCCTCAGCTTGGGAAGATAGATTTTTTTCCCCCCAATTACAAAATCTAAGTATTTTGGCCCTTC
AATTTGGAGGAGGGCAAAAGTTGGAAGTAAGAAGTTTTATTTTAAGTACTTTCAGTGCTCAAAAAAATGCAATCACTGTGTTGTATATAA
TAGTTCATAGGTTGATCACTCATAATAATTGACTCTAAGGCTTTTATTAAGAAAACAGCAGAAAGATTAAATCTTGAATTAAGTCTGGGG
GGAAATGGCCACTGCAGATGGAGTTTTAGAGTAGTAATGAAATTCTACCTAGAATGCAAAATTGGGTATATGAATTACATAGCATGTTGT
TGGGATTTTTTTTAATGTGCAGAAGATCAAAGCTACTTGGAAGGAGTGCCTATAATTTGCCAGTAGCCACAGATTAAGATTATATCTTAT
ATATCAGCAGATTAGCTTTAGCTTAGGGGGAGGGTGGGAAAGTTTGGGGGGGGGGTTGTGAAGATTTAGGGGGACCTTGATAGAGAACTT
TATAAACTTCTTTCTCTTTAATAAAGACTTGTCTTACACCGTGCTGCCATTAAAGGCAGCTGTTCTAGAGTTTCAGTCACCTAAGTACAC
CCACAAAACAATATGAATATGGAGATCTTCCTTTACCCCTCAACTTTAATTTGCCCAGTTATACCTCAGTGTTGTAGCAGTACTGTGATA
CCTGGCACAGTGCTTTGATCTTACGATGCCCTCTGTACTGACCTGAAGGAGACCTAAGAGTCCTTTCCCTTTTTGAGTTTGAATCATAGC
CTTGATGTGGTCTCTTGTTTTATGTCCTTGTTCCTAATGTAAAAGTGCTTAACTGCTTCTTGGTTGTATTGGGTAGCATTGGGATAAGAT
TTTAACTGGGTATTCTTGAATTGCTTTTACAATAAACCAATTTTATAATCTTTAAATTTATCAACTTTTTACATTTGTGTTATTTTCAGT
CAGGGCTTCTTAGATCTACTTATGGTTGATGGAGCACATTGATTTGGAGTTTCAGATCTTCCAAAGCACTATTTGTTGTAATAACTTTTC
TAAATGTAGTGCCTTTAAAGGAAAAATGAACACAGGGAAGTGACTTTGCTACAAATAATGTTGCTGTGTTAAGTATTCATATTAAATACA
TGCCTTCTATATGGAACATGGCAGAAAGACTGAAAAATAACAGTAATTAATTGTGTAATTCAGAATTCATACCAATCAGTGTTGAAACTC
AAACATTGCAAAAGTGGGTGGCAATATTCAGTGCTTAACACTTTTCTAGCGTTGGTACATCTGAGAAATGAGTGCTCAGGTGGATTTTAT
CCTCGCAAGCATGTTGTTATAAGAATTGTGGGTGTGCCTATCATAACAATTGTTTTCTGTATCTTGAAAAAGTATTCTCCACATTTTAAA
TGTTTTATATTAGAGAATTCTTTAATGCACACTTGTCAAATATATATATATAGTACCAATGTTACCTTTTTATTTTTTGTTTTAGATGTA
AGAGCATGCTCATATGTTAGGTACTTACATAAATTGTTACATTATTTTTTCTTATGTAATACCTTTTTGTTTGTTTATGTGGTTCAAATA

>In-frame_ENST00000393695_ENST00000282441_TCGA-GN-A4U7-06A_NUMA1_chr11_71746948_-_YAP1_chr11_102094353_length(amino acids)=180AA_start in transcript=314_stop in transcript=856
MSGITKMTLHATRGAALLSWELALRSQLPTLEQDGGTQNPVSSPGMSQELRTMTTNSSDPFLNSGTYHSRDESTDSGLSMSSYSVPRTPD
DFLNSVDEMDTGDTINQSTLPSQQNRFPDYLEAIPGTNVDLGTLEGDGMNIEGEELMPSLQEALSSDILNDMESVLAATKLDKESFLTWL

--------------------------------------------------------------
>In-frame_ENST00000393695_ENST00000537274_TCGA-GN-A4U7-06A_NUMA1_chr11_71746948_-_YAP1_chr11_102094353_length(transcript)=4340nt_BP=374nt
AAGTACAGGCCGGGGTCCGGAAGCGGTGATACCCCTTCTCTTTCCCAGTGGCCCTCAAACTTCCTTTTCCCGGGTCCTTAAGCGGGCCCC
GCCGACAGAGGCCAATCAGAGGGCAGCGCGAGGGGGCGGGGCCATAGTTTAAACTAATTGTGCGCTCACAGCGCTGGCGCGAGCCCACGA
AGAGGTACGATTCCGGAGAATCGCGAGGCAGAGCGGGAGCGCGCAGCCAGGTGGAAACTAATTCTAAGCCAGACTGCTGGAGATCACCCT
GTTCTAGTGTGTGGAGGCTTCCACCAGGAGGCGCATTGGAGTGACTGTCTGGCATCACCAAGATGACACTCCACGCCACCCGGGGGGCTG
CACTCCTCTCTTGGGAGTTAGCCCTGCGTAGCCAGTTACCAACACTGGAGCAGGATGGTGGGACTCAAAATCCAGTGTCTTCTCCCGGGA
TGTCTCAGGAATTGAGAACAATGACGACCAATAGCTCAGATCCTTTCCTTAACAGTGGCACCTATCACTCTCGAGATGAGAGTACAGACA
GTGGACTAAGCATGAGCAGCTACAGTGTCCCTCGAACCCCAGATGACTTCCTGAACAGTGTGGATGAGATGGATACAGGTGATACTATCA
ACCAAAGCACCCTGCCCTCACAGCAGAACCGTTTCCCAGACTACCTTGAAGCCATTCCTGGGACAAATGTGGACCTTGGAACACTGGAAG
GAGATGGAATGAACATAGAAGGAGAGGAGCTGATGCCAAGTCTGCAGGAAGCTTTGAGTTCTGACATCCTTAATGACATGGAGTCTGTTT
TGGCTGCCACCAAGCTAGATAAAGAAAGCTTTCTTACATGGTTATAGAGCCCTCAGGCAGACTGAATTCTAAATCTGTGAAGGATCTAAG
GAGACACATGCACCGGAAATTTCCATAAGCCAGTTGCAGTTTTCAGGCTAATACAGAAAAAGATGAACAAACGTCCAGCAAGATACTTTA
ATCCTCTATTTTGCTCTTCCTTGTCCATTGCTGCTGTTAATGTATTGCTGACCTCTTTCACAGTTGGCTCTAAAGAATCAAAAGAAAAAA
ACTTTTTATTTCTTTTGCTATTAAAACTACTGTTCATTTTGGGGGCTGGGGGAAGTGAGCCTGTTTGGATGATGGATGCCATTCCTTTTG
CCCAGTTAAATGTTCACCAATCATTTTAACTAAATACTCAGACTTAGAAGTCAGATGCTTCATGTCACAGCATTTAGTTTGTTCAACAGT
TGTTTCTTCAGCTTCCTTTGTCCAGTGGAAAAACATGATTTACTGGTCTGACAAGCCAAAAATGTTATATCTGATATTAAATACTTAATG
CTGATTTGAAGAGATAGCTGAAACCAAGGCTGAAGACTGTTTTACTTTCAGTATTTTCTTTTCCTCCTAGTGCTATCATTAGTCACATAA
TGACCTTGATTTTATTTTAGGAGCTTATAAGGCATGAGACAATTTCCATATAAATATATTAATTATTGCCACATACTCTAATATAGATTT
TGGTGGATAATTTTGTGGGTGTGCATTTTGTTCTGTTTTGTTGGGTTTTTTGTTTTTTTTGTTTTTGGCAGGGTCGGTGGGGGGGTTGGT
TGGTTGGTTGGTTTTGTCGGAACCTAGGCAAATGACCATATTAGTGAATCTGTTAATAGTTGTAGCTTGGGATGGTTATTGTAGTTGTTT
TGGTAAAATCTTCATTTCCTGGTTTTTTTTACCACCTTATTTAAATCTCGATTATCTGCTCTCTCTTTTATATACATACACACACCCAAA
CATAACATTTATAATAGTGTGGTAGTGGAATGTATCCTTTTTTAGGTTTCCCTGCTTTCCAGTTAATTTTTAAAATGGTAGCGCTTTGTA
TGCATTTAGAATACATGACTAGTAGTTTATATTTCACTGGTAGTTTAAATCTGGTTGGGGCAGTCTGCAGATGTTTGAAGTAGTTTAGTG
TTCTAGAAAGAGCTATTACTGTGGATAGTGCCTAGGGGAGTGCTCCACGCCCTCTGGGCATACGGTAGATATTATCTGATGAATTGGAAA
GGAGCAAACCAGAAATGGCTTTATTTTCTCCCTTGGACTAATTTTTAAGTCTCGATTGGAATTCAGTGAGTAGGTTCATAATGTGCATGA
CAGAAATAAGCTTTATAGTGGTTTACCTTCATTTAGCTTTGGAAGTTTTCTTTGCCTTAGTTTTGGAAGTAAATTCTAGTTTGTAGTTCT
CATTTGTAATGAACACATTAACGACTAGATTAAAATATTGCCTTCAAGATTGTTCTTACTTACAAGACTTGCTCCTACTTCTATGCTGAA
AATTGACCCTGGATAGAATACTATAAGGTTTTGAGTTAGCTGGAAAAGTGATCAGATTAATAAATGTATATTGGTAGTTGAATTTAGCAA
AGAAATAGAGATAATCATGATTATACCTTTATTTTTACAGGAAGAGATGATGTAACTAGAGTATGTGTCTACAGGAGTAATAATGGTTTC
CAAAGAGTATTTTTTAAAGGAACAAAACGAGCATGAATTAACTCTTCAATATAAGCTATGAAGTAATAGTTGGTTGTGAATTAAAGTGGC
ACCAGCTAGCACCTCTGTGTTTTAAGGGTCTTTCAATGTTTCTAGAATAAGCCCTTATTTTCAAGGGTTCATAACAGGCATAAAATCTCT
TCTCCTGGCAAAAGCTGCTATGAAAAGCCTCAGCTTGGGAAGATAGATTTTTTTCCCCCCAATTACAAAATCTAAGTATTTTGGCCCTTC
AATTTGGAGGAGGGCAAAAGTTGGAAGTAAGAAGTTTTATTTTAAGTACTTTCAGTGCTCAAAAAAATGCAATCACTGTGTTGTATATAA
TAGTTCATAGGTTGATCACTCATAATAATTGACTCTAAGGCTTTTATTAAGAAAACAGCAGAAAGATTAAATCTTGAATTAAGTCTGGGG
GGAAATGGCCACTGCAGATGGAGTTTTAGAGTAGTAATGAAATTCTACCTAGAATGCAAAATTGGGTATATGAATTACATAGCATGTTGT
TGGGATTTTTTTTAATGTGCAGAAGATCAAAGCTACTTGGAAGGAGTGCCTATAATTTGCCAGTAGCCACAGATTAAGATTATATCTTAT
ATATCAGCAGATTAGCTTTAGCTTAGGGGGAGGGTGGGAAAGTTTGGGGGGGGGGTTGTGAAGATTTAGGGGGACCTTGATAGAGAACTT
TATAAACTTCTTTCTCTTTAATAAAGACTTGTCTTACACCGTGCTGCCATTAAAGGCAGCTGTTCTAGAGTTTCAGTCACCTAAGTACAC
CCACAAAACAATATGAATATGGAGATCTTCCTTTACCCCTCAACTTTAATTTGCCCAGTTATACCTCAGTGTTGTAGCAGTACTGTGATA
CCTGGCACAGTGCTTTGATCTTACGATGCCCTCTGTACTGACCTGAAGGAGACCTAAGAGTCCTTTCCCTTTTTGAGTTTGAATCATAGC
CTTGATGTGGTCTCTTGTTTTATGTCCTTGTTCCTAATGTAAAAGTGCTTAACTGCTTCTTGGTTGTATTGGGTAGCATTGGGATAAGAT
TTTAACTGGGTATTCTTGAATTGCTTTTACAATAAACCAATTTTATAATCTTTAAATTTATCAACTTTTTACATTTGTGTTATTTTCAGT
CAGGGCTTCTTAGATCTACTTATGGTTGATGGAGCACATTGATTTGGAGTTTCAGATCTTCCAAAGCACTATTTGTTGTAATAACTTTTC
TAAATGTAGTGCCTTTAAAGGAAAAATGAACACAGGGAAGTGACTTTGCTACAAATAATGTTGCTGTGTTAAGTATTCATATTAAATACA
TGCCTTCTATATGGAACATGGCAGAAAGACTGAAAAATAACAGTAATTAATTGTGTAATTCAGAATTCATACCAATCAGTGTTGAAACTC
AAACATTGCAAAAGTGGGTGGCAATATTCAGTGCTTAACACTTTTCTAGCGTTGGTACATCTGAGAAATGAGTGCTCAGGTGGATTTTAT
CCTCGCAAGCATGTTGTTATAAGAATTGTGGGTGTGCCTATCATAACAATTGTTTTCTGTATCTTGAAAAAGTATTCTCCACATTTTAAA
TGTTTTATATTAGAGAATTCTTTAATGCACACTTGTCAAATATATATATATAGTACCAATGTTACCTTTTTATTTTTTGTTTTAGATGTA
AGAGCATGCTCATATGTTAGGTACTTACATAAATTGTTACATTATTTTTTCTTATGTAATACCTTTTTGTTTGTTTATGTGGTTCAAATA

>In-frame_ENST00000393695_ENST00000537274_TCGA-GN-A4U7-06A_NUMA1_chr11_71746948_-_YAP1_chr11_102094353_length(amino acids)=180AA_start in transcript=314_stop in transcript=856
MSGITKMTLHATRGAALLSWELALRSQLPTLEQDGGTQNPVSSPGMSQELRTMTTNSSDPFLNSGTYHSRDESTDSGLSMSSYSVPRTPD
DFLNSVDEMDTGDTINQSTLPSQQNRFPDYLEAIPGTNVDLGTLEGDGMNIEGEELMPSLQEALSSDILNDMESVLAATKLDKESFLTWL

--------------------------------------------------------------
>In-frame_ENST00000393695_ENST00000345877_TCGA-GN-A4U7-06A_NUMA1_chr11_71746948_-_YAP1_chr11_102094353_length(transcript)=4340nt_BP=374nt
AAGTACAGGCCGGGGTCCGGAAGCGGTGATACCCCTTCTCTTTCCCAGTGGCCCTCAAACTTCCTTTTCCCGGGTCCTTAAGCGGGCCCC
GCCGACAGAGGCCAATCAGAGGGCAGCGCGAGGGGGCGGGGCCATAGTTTAAACTAATTGTGCGCTCACAGCGCTGGCGCGAGCCCACGA
AGAGGTACGATTCCGGAGAATCGCGAGGCAGAGCGGGAGCGCGCAGCCAGGTGGAAACTAATTCTAAGCCAGACTGCTGGAGATCACCCT
GTTCTAGTGTGTGGAGGCTTCCACCAGGAGGCGCATTGGAGTGACTGTCTGGCATCACCAAGATGACACTCCACGCCACCCGGGGGGCTG
CACTCCTCTCTTGGGAGTTAGCCCTGCGTAGCCAGTTACCAACACTGGAGCAGGATGGTGGGACTCAAAATCCAGTGTCTTCTCCCGGGA
TGTCTCAGGAATTGAGAACAATGACGACCAATAGCTCAGATCCTTTCCTTAACAGTGGCACCTATCACTCTCGAGATGAGAGTACAGACA
GTGGACTAAGCATGAGCAGCTACAGTGTCCCTCGAACCCCAGATGACTTCCTGAACAGTGTGGATGAGATGGATACAGGTGATACTATCA
ACCAAAGCACCCTGCCCTCACAGCAGAACCGTTTCCCAGACTACCTTGAAGCCATTCCTGGGACAAATGTGGACCTTGGAACACTGGAAG
GAGATGGAATGAACATAGAAGGAGAGGAGCTGATGCCAAGTCTGCAGGAAGCTTTGAGTTCTGACATCCTTAATGACATGGAGTCTGTTT
TGGCTGCCACCAAGCTAGATAAAGAAAGCTTTCTTACATGGTTATAGAGCCCTCAGGCAGACTGAATTCTAAATCTGTGAAGGATCTAAG
GAGACACATGCACCGGAAATTTCCATAAGCCAGTTGCAGTTTTCAGGCTAATACAGAAAAAGATGAACAAACGTCCAGCAAGATACTTTA
ATCCTCTATTTTGCTCTTCCTTGTCCATTGCTGCTGTTAATGTATTGCTGACCTCTTTCACAGTTGGCTCTAAAGAATCAAAAGAAAAAA
ACTTTTTATTTCTTTTGCTATTAAAACTACTGTTCATTTTGGGGGCTGGGGGAAGTGAGCCTGTTTGGATGATGGATGCCATTCCTTTTG
CCCAGTTAAATGTTCACCAATCATTTTAACTAAATACTCAGACTTAGAAGTCAGATGCTTCATGTCACAGCATTTAGTTTGTTCAACAGT
TGTTTCTTCAGCTTCCTTTGTCCAGTGGAAAAACATGATTTACTGGTCTGACAAGCCAAAAATGTTATATCTGATATTAAATACTTAATG
CTGATTTGAAGAGATAGCTGAAACCAAGGCTGAAGACTGTTTTACTTTCAGTATTTTCTTTTCCTCCTAGTGCTATCATTAGTCACATAA
TGACCTTGATTTTATTTTAGGAGCTTATAAGGCATGAGACAATTTCCATATAAATATATTAATTATTGCCACATACTCTAATATAGATTT
TGGTGGATAATTTTGTGGGTGTGCATTTTGTTCTGTTTTGTTGGGTTTTTTGTTTTTTTTGTTTTTGGCAGGGTCGGTGGGGGGGTTGGT
TGGTTGGTTGGTTTTGTCGGAACCTAGGCAAATGACCATATTAGTGAATCTGTTAATAGTTGTAGCTTGGGATGGTTATTGTAGTTGTTT
TGGTAAAATCTTCATTTCCTGGTTTTTTTTACCACCTTATTTAAATCTCGATTATCTGCTCTCTCTTTTATATACATACACACACCCAAA
CATAACATTTATAATAGTGTGGTAGTGGAATGTATCCTTTTTTAGGTTTCCCTGCTTTCCAGTTAATTTTTAAAATGGTAGCGCTTTGTA
TGCATTTAGAATACATGACTAGTAGTTTATATTTCACTGGTAGTTTAAATCTGGTTGGGGCAGTCTGCAGATGTTTGAAGTAGTTTAGTG
TTCTAGAAAGAGCTATTACTGTGGATAGTGCCTAGGGGAGTGCTCCACGCCCTCTGGGCATACGGTAGATATTATCTGATGAATTGGAAA
GGAGCAAACCAGAAATGGCTTTATTTTCTCCCTTGGACTAATTTTTAAGTCTCGATTGGAATTCAGTGAGTAGGTTCATAATGTGCATGA
CAGAAATAAGCTTTATAGTGGTTTACCTTCATTTAGCTTTGGAAGTTTTCTTTGCCTTAGTTTTGGAAGTAAATTCTAGTTTGTAGTTCT
CATTTGTAATGAACACATTAACGACTAGATTAAAATATTGCCTTCAAGATTGTTCTTACTTACAAGACTTGCTCCTACTTCTATGCTGAA
AATTGACCCTGGATAGAATACTATAAGGTTTTGAGTTAGCTGGAAAAGTGATCAGATTAATAAATGTATATTGGTAGTTGAATTTAGCAA
AGAAATAGAGATAATCATGATTATACCTTTATTTTTACAGGAAGAGATGATGTAACTAGAGTATGTGTCTACAGGAGTAATAATGGTTTC
CAAAGAGTATTTTTTAAAGGAACAAAACGAGCATGAATTAACTCTTCAATATAAGCTATGAAGTAATAGTTGGTTGTGAATTAAAGTGGC
ACCAGCTAGCACCTCTGTGTTTTAAGGGTCTTTCAATGTTTCTAGAATAAGCCCTTATTTTCAAGGGTTCATAACAGGCATAAAATCTCT
TCTCCTGGCAAAAGCTGCTATGAAAAGCCTCAGCTTGGGAAGATAGATTTTTTTCCCCCCAATTACAAAATCTAAGTATTTTGGCCCTTC
AATTTGGAGGAGGGCAAAAGTTGGAAGTAAGAAGTTTTATTTTAAGTACTTTCAGTGCTCAAAAAAATGCAATCACTGTGTTGTATATAA
TAGTTCATAGGTTGATCACTCATAATAATTGACTCTAAGGCTTTTATTAAGAAAACAGCAGAAAGATTAAATCTTGAATTAAGTCTGGGG
GGAAATGGCCACTGCAGATGGAGTTTTAGAGTAGTAATGAAATTCTACCTAGAATGCAAAATTGGGTATATGAATTACATAGCATGTTGT
TGGGATTTTTTTTAATGTGCAGAAGATCAAAGCTACTTGGAAGGAGTGCCTATAATTTGCCAGTAGCCACAGATTAAGATTATATCTTAT
ATATCAGCAGATTAGCTTTAGCTTAGGGGGAGGGTGGGAAAGTTTGGGGGGGGGGTTGTGAAGATTTAGGGGGACCTTGATAGAGAACTT
TATAAACTTCTTTCTCTTTAATAAAGACTTGTCTTACACCGTGCTGCCATTAAAGGCAGCTGTTCTAGAGTTTCAGTCACCTAAGTACAC
CCACAAAACAATATGAATATGGAGATCTTCCTTTACCCCTCAACTTTAATTTGCCCAGTTATACCTCAGTGTTGTAGCAGTACTGTGATA
CCTGGCACAGTGCTTTGATCTTACGATGCCCTCTGTACTGACCTGAAGGAGACCTAAGAGTCCTTTCCCTTTTTGAGTTTGAATCATAGC
CTTGATGTGGTCTCTTGTTTTATGTCCTTGTTCCTAATGTAAAAGTGCTTAACTGCTTCTTGGTTGTATTGGGTAGCATTGGGATAAGAT
TTTAACTGGGTATTCTTGAATTGCTTTTACAATAAACCAATTTTATAATCTTTAAATTTATCAACTTTTTACATTTGTGTTATTTTCAGT
CAGGGCTTCTTAGATCTACTTATGGTTGATGGAGCACATTGATTTGGAGTTTCAGATCTTCCAAAGCACTATTTGTTGTAATAACTTTTC
TAAATGTAGTGCCTTTAAAGGAAAAATGAACACAGGGAAGTGACTTTGCTACAAATAATGTTGCTGTGTTAAGTATTCATATTAAATACA
TGCCTTCTATATGGAACATGGCAGAAAGACTGAAAAATAACAGTAATTAATTGTGTAATTCAGAATTCATACCAATCAGTGTTGAAACTC
AAACATTGCAAAAGTGGGTGGCAATATTCAGTGCTTAACACTTTTCTAGCGTTGGTACATCTGAGAAATGAGTGCTCAGGTGGATTTTAT
CCTCGCAAGCATGTTGTTATAAGAATTGTGGGTGTGCCTATCATAACAATTGTTTTCTGTATCTTGAAAAAGTATTCTCCACATTTTAAA
TGTTTTATATTAGAGAATTCTTTAATGCACACTTGTCAAATATATATATATAGTACCAATGTTACCTTTTTATTTTTTGTTTTAGATGTA
AGAGCATGCTCATATGTTAGGTACTTACATAAATTGTTACATTATTTTTTCTTATGTAATACCTTTTTGTTTGTTTATGTGGTTCAAATA

>In-frame_ENST00000393695_ENST00000345877_TCGA-GN-A4U7-06A_NUMA1_chr11_71746948_-_YAP1_chr11_102094353_length(amino acids)=180AA_start in transcript=314_stop in transcript=856
MSGITKMTLHATRGAALLSWELALRSQLPTLEQDGGTQNPVSSPGMSQELRTMTTNSSDPFLNSGTYHSRDESTDSGLSMSSYSVPRTPD
DFLNSVDEMDTGDTINQSTLPSQQNRFPDYLEAIPGTNVDLGTLEGDGMNIEGEELMPSLQEALSSDILNDMESVLAATKLDKESFLTWL

--------------------------------------------------------------
>In-frame_ENST00000393695_ENST00000531439_TCGA-GN-A4U7-06A_NUMA1_chr11_71746948_-_YAP1_chr11_102094353_length(transcript)=880nt_BP=374nt
AAGTACAGGCCGGGGTCCGGAAGCGGTGATACCCCTTCTCTTTCCCAGTGGCCCTCAAACTTCCTTTTCCCGGGTCCTTAAGCGGGCCCC
GCCGACAGAGGCCAATCAGAGGGCAGCGCGAGGGGGCGGGGCCATAGTTTAAACTAATTGTGCGCTCACAGCGCTGGCGCGAGCCCACGA
AGAGGTACGATTCCGGAGAATCGCGAGGCAGAGCGGGAGCGCGCAGCCAGGTGGAAACTAATTCTAAGCCAGACTGCTGGAGATCACCCT
GTTCTAGTGTGTGGAGGCTTCCACCAGGAGGCGCATTGGAGTGACTGTCTGGCATCACCAAGATGACACTCCACGCCACCCGGGGGGCTG
CACTCCTCTCTTGGGAGTTAGCCCTGCGTAGCCAGTTACCAACACTGGAGCAGGATGGTGGGACTCAAAATCCAGTGTCTTCTCCCGGGA
TGTCTCAGGAATTGAGAACAATGACGACCAATAGCTCAGATCCTTTCCTTAACAGTGGCACCTATCACTCTCGAGATGAGAGTACAGACA
GTGGACTAAGCATGAGCAGCTACAGTGTCCCTCGAACCCCAGATGACTTCCTGAACAGTGTGGATGAGATGGATACAGGTGATACTATCA
ACCAAAGCACCCTGCCCTCACAGCAGAACCGTTTCCCAGACTACCTTGAAGCCATTCCTGGGACAAATGTGGACCTTGGAACACTGGAAG
GAGATGGAATGAACATAGAAGGAGAGGAGCTGATGCCAAGTCTGCAGGAAGCTTTGAGTTCTGACATCCTTAATGACATGGAGTCTGTTT

>In-frame_ENST00000393695_ENST00000531439_TCGA-GN-A4U7-06A_NUMA1_chr11_71746948_-_YAP1_chr11_102094353_length(amino acids)=180AA_start in transcript=314_stop in transcript=856
MSGITKMTLHATRGAALLSWELALRSQLPTLEQDGGTQNPVSSPGMSQELRTMTTNSSDPFLNSGTYHSRDESTDSGLSMSSYSVPRTPD
DFLNSVDEMDTGDTINQSTLPSQQNRFPDYLEAIPGTNVDLGTLEGDGMNIEGEELMPSLQEALSSDILNDMESVLAATKLDKESFLTWL

--------------------------------------------------------------
>In-frame_ENST00000393695_ENST00000524575_TCGA-GN-A4U7-06A_NUMA1_chr11_71746948_-_YAP1_chr11_102094353_length(transcript)=1069nt_BP=374nt
AAGTACAGGCCGGGGTCCGGAAGCGGTGATACCCCTTCTCTTTCCCAGTGGCCCTCAAACTTCCTTTTCCCGGGTCCTTAAGCGGGCCCC
GCCGACAGAGGCCAATCAGAGGGCAGCGCGAGGGGGCGGGGCCATAGTTTAAACTAATTGTGCGCTCACAGCGCTGGCGCGAGCCCACGA
AGAGGTACGATTCCGGAGAATCGCGAGGCAGAGCGGGAGCGCGCAGCCAGGTGGAAACTAATTCTAAGCCAGACTGCTGGAGATCACCCT
GTTCTAGTGTGTGGAGGCTTCCACCAGGAGGCGCATTGGAGTGACTGTCTGGCATCACCAAGATGACACTCCACGCCACCCGGGGGGCTG
CACTCCTCTCTTGGGAGTTAGCCCTGCGTAGCCAGTTACCAACACTGGAGCAGGATGGTGGGACTCAAAATCCAGTGTCTTCTCCCGGGA
TGTCTCAGGAATTGAGAACAATGACGACCAATAGCTCAGATCCTTTCCTTAACAGTGGCACCTATCACTCTCGAGATGAGAGTACAGACA
GTGGACTAAGCATGAGCAGCTACAGTGTCCCTCGAACCCCAGATGACTTCCTGAACAGTGTGGATGAGATGGATACAGGTGATACTATCA
ACCAAAGCACCCTGCCCTCACAGCAGAACCGTTTCCCAGACTACCTTGAAGCCATTCCTGGGACAAATGTGGACCTTGGAACACTGGAAG
GAGATGGAATGAACATAGAAGGAGAGGAGCTGATGCCAAGTCTGCAGGAAGCTTTGAGTTCTGACATCCTTAATGACATGGAGTCTGTTT
TGGCTGCCACCAAGCTAGATAAAGAAAGCTTTCTTACATGGTTATAGAGCCCTCAGGCAGACTGAATTCTAAATCTGTGAAGGATCTAAG
GAGACACATGCACCGGAAATTTCCATAAGCCAGTTGCAGTTTTCAGGCTAATACAGAAAAAGATGAACAAACGTCCAGCAAGATACTTTA

>In-frame_ENST00000393695_ENST00000524575_TCGA-GN-A4U7-06A_NUMA1_chr11_71746948_-_YAP1_chr11_102094353_length(amino acids)=180AA_start in transcript=314_stop in transcript=856
MSGITKMTLHATRGAALLSWELALRSQLPTLEQDGGTQNPVSSPGMSQELRTMTTNSSDPFLNSGTYHSRDESTDSGLSMSSYSVPRTPD
DFLNSVDEMDTGDTINQSTLPSQQNRFPDYLEAIPGTNVDLGTLEGDGMNIEGEELMPSLQEALSSDILNDMESVLAATKLDKESFLTWL

--------------------------------------------------------------

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Fusion Gene PPI Analysis for NUMA1-YAP1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for NUMA1-YAP1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for NUMA1-YAP1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneNUMA1C0023487Acute Promyelocytic Leukemia1CTD_human;ORPHANET
HgeneNUMA1C0162820Dermatitis, Allergic Contact1CTD_human
TgeneYAP1C3805432COLOBOMA, OCULAR, WITH OR WITHOUT HEARING IMPAIRMENT, CLEFT LIP/PALATE, AND/OR MENTAL RETARDATION3CTD_human;GENOMICS_ENGLAND
TgeneYAP1C0006118Brain Neoplasms1CTD_human
TgeneYAP1C0006142Malignant neoplasm of breast1CTD_human
TgeneYAP1C0009402Colorectal Carcinoma1CTD_human
TgeneYAP1C0009404Colorectal Neoplasms1CTD_human
TgeneYAP1C0018916Hemangioma1CTD_human
TgeneYAP1C0027627Neoplasm Metastasis1CTD_human
TgeneYAP1C0027819Neuroblastoma1CTD_human
TgeneYAP1C0153633Malignant neoplasm of brain1CTD_human
TgeneYAP1C0205788Histiocytoid hemangioma1CTD_human
TgeneYAP1C0205789Hemangioma, Intramuscular1CTD_human
TgeneYAP1C0206656Embryonal Rhabdomyosarcoma1CTD_human
TgeneYAP1C0206732Epithelioid hemangioendothelioma1ORPHANET
TgeneYAP1C0235874Disease Exacerbation1CTD_human
TgeneYAP1C0496899Benign neoplasm of brain, unspecified1CTD_human
TgeneYAP1C0677608Chorioangioma1CTD_human
TgeneYAP1C0678222Breast Carcinoma1CTD_human
TgeneYAP1C0750974Brain Tumor, Primary1CTD_human
TgeneYAP1C0750977Recurrent Brain Neoplasm1CTD_human
TgeneYAP1C0750979Primary malignant neoplasm of brain1CTD_human
TgeneYAP1C0795902Coloboma, cleft lip-palate and mental retardation syndrome1ORPHANET
TgeneYAP1C0919267ovarian neoplasm1CTD_human
TgeneYAP1C1140680Malignant neoplasm of ovary1CTD_human
TgeneYAP1C1168401Squamous cell carcinoma of the head and neck1CTD_human
TgeneYAP1C1257931Mammary Neoplasms, Human1CTD_human
TgeneYAP1C1458155Mammary Neoplasms1CTD_human
TgeneYAP1C1527390Neoplasms, Intracranial1CTD_human
TgeneYAP1C1959588Angioma1CTD_human
TgeneYAP1C2239176Liver carcinoma1CTD_human
TgeneYAP1C3539878Triple Negative Breast Neoplasms1CTD_human
TgeneYAP1C4704874Mammary Carcinoma, Human1CTD_human