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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:NUP98-HOXC13 (FusionGDB2 ID:60737)

Fusion Gene Summary for NUP98-HOXC13

check button Fusion gene summary
Fusion gene informationFusion gene name: NUP98-HOXC13
Fusion gene ID: 60737
HgeneTgene
Gene symbol

NUP98

HOXC13

Gene ID

4928

3229

Gene namenucleoporin 98 and 96 precursorhomeobox C13
SynonymsADIR2|NUP196|NUP96|Nup98-96ECTD9|HOX3|HOX3G
Cytomap

11p15.4

12q13.13

Type of geneprotein-codingprotein-coding
Descriptionnuclear pore complex protein Nup98-Nup96nuclear pore complex protein Nup98GLFG-repeat containing nucleoporinNUP98/PHF23 fusion 2 proteinNup98-Nup96nucleoporin 96nucleoporin 98kDnucleoporin 98kDahomeobox protein Hox-C13NUP98/HOXC13homeo box 3Ghomeobox protein Hox-3G
Modification date2020031320200313
UniProtAcc.

P31276

Ensembl transtripts involved in fusion geneENST00000324932, ENST00000359171, 
ENST00000355260, ENST00000397004, 
ENST00000397007, ENST00000488828, 
ENST00000243056, 
Fusion gene scores* DoF score35 X 37 X 11=142452 X 4 X 4=32
# samples 313
** MAII scorelog2(31/14245*10)=-5.52204359593698
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(3/32*10)=-0.0931094043914815
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: NUP98 [Title/Abstract] AND HOXC13 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointNUP98(3756553)-HOXC13(54338780), # samples:1
NUP98(3744387)-HOXC13(54338780), # samples:1
Anticipated loss of major functional domain due to fusion event.NUP98-HOXC13 seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF.
NUP98-HOXC13 seems lost the major protein functional domain in Hgene partner, which is a tumor suppressor due to the frame-shifted ORF.
NUP98-HOXC13 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
NUP98-HOXC13 seems lost the major protein functional domain in Tgene partner, which is a transcription factor due to the frame-shifted ORF.
NUP98-HOXC13 seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across NUP98 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across HOXC13 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4acute myeloid leukemiaAJ438986NUP98chr11

3756553

HOXC13chr12

54338780

ChiTaRS5.0N/AAJ438986NUP98chr11

3744387

-HOXC13chr12

54338780

+


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Fusion Gene ORF analysis for NUP98-HOXC13

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
intron-3CDSENST00000324932ENST00000243056NUP98chr11

3756553

HOXC13chr12

54338780

intron-3CDSENST00000359171ENST00000243056NUP98chr11

3756553

HOXC13chr12

54338780

intron-3CDSENST00000355260ENST00000243056NUP98chr11

3756553

HOXC13chr12

54338780

intron-3CDSENST00000397004ENST00000243056NUP98chr11

3756553

HOXC13chr12

54338780

intron-3CDSENST00000397007ENST00000243056NUP98chr11

3756553

HOXC13chr12

54338780

intron-3CDSENST00000488828ENST00000243056NUP98chr11

3756553

HOXC13chr12

54338780

In-frameENST00000324932ENST00000243056NUP98chr11

3744387

-HOXC13chr12

54338780

+
Frame-shiftENST00000359171ENST00000243056NUP98chr11

3744387

-HOXC13chr12

54338780

+
In-frameENST00000355260ENST00000243056NUP98chr11

3744387

-HOXC13chr12

54338780

+
In-frameENST00000397004ENST00000243056NUP98chr11

3744387

-HOXC13chr12

54338780

+
In-frameENST00000397007ENST00000243056NUP98chr11

3744387

-HOXC13chr12

54338780

+
intron-3CDSENST00000488828ENST00000243056NUP98chr11

3744387

-HOXC13chr12

54338780

+
Frame-shiftENST00000359171ENST00000243056NUP98chr11

3744386

-HOXC13chr12

54338783

+
In-frameENST00000324932ENST00000243056NUP98chr11

3744386

-HOXC13chr12

54338783

+
In-frameENST00000355260ENST00000243056NUP98chr11

3744386

-HOXC13chr12

54338783

+
In-frameENST00000397004ENST00000243056NUP98chr11

3744386

-HOXC13chr12

54338783

+
In-frameENST00000397007ENST00000243056NUP98chr11

3744386

-HOXC13chr12

54338783

+
intron-3CDSENST00000488828ENST00000243056NUP98chr11

3744386

-HOXC13chr12

54338783

+
intron-intronENST00000324932ENST00000243056NUP98chr11

3744685

-HOXC13chr12

3744685

+
intron-intronENST00000355260ENST00000243056NUP98chr11

3744685

-HOXC13chr12

3744685

+
intron-intronENST00000359171ENST00000243056NUP98chr11

3744685

-HOXC13chr12

3744685

+
intron-intronENST00000397004ENST00000243056NUP98chr11

3744685

-HOXC13chr12

3744685

+
intron-intronENST00000397007ENST00000243056NUP98chr11

3744685

-HOXC13chr12

3744685

+
intron-intronENST00000488828ENST00000243056NUP98chr11

3744685

-HOXC13chr12

3744685

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000324932NUP98chr113744387-ENST00000243056HOXC13chr1254338780+411225673972823808
ENST00000355260NUP98chr113744387-ENST00000243056HOXC13chr1254338780+37782233632489808
ENST00000397004NUP98chr113744387-ENST00000243056HOXC13chr1254338780+386123161462572808
ENST00000397007NUP98chr113744387-ENST00000243056HOXC13chr1254338780+391823731522629825

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000324932ENST00000243056NUP98chr113744387-HOXC13chr1254338780+0.0019373220.9980627
ENST00000355260ENST00000243056NUP98chr113744387-HOXC13chr1254338780+0.002086570.9979134
ENST00000397004ENST00000243056NUP98chr113744387-HOXC13chr1254338780+0.0019991790.9980008
ENST00000397007ENST00000243056NUP98chr113744387-HOXC13chr1254338780+0.0020914070.9979086

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Fusion Genomic Features for NUP98-HOXC13


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
NUP98chr113744386-HOXC13chr1254338783+1.04E-101
NUP98chr113744386-HOXC13chr1254338783+1.04E-101

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for NUP98-HOXC13


check button Go to

FGviewer for the breakpoints of chr11:3744387-chr12:54338780

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.HOXC13

P31276

FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Transcription factor which plays a role in hair follicle differentiation. Regulates FOXQ1 expression and that of other hair-specific genes (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNUP98chr11:3744387chr12:54338780ENST00000324932-16337_480715.33333333333341801.0Compositional biasNote=Gly/Thr-rich
HgeneNUP98chr11:3744387chr12:54338780ENST00000355260-16327_480715.33333333333341727.0Compositional biasNote=Gly/Thr-rich
HgeneNUP98chr11:3744387chr12:54338780ENST00000397004-16207_480715.3333333333334921.0Compositional biasNote=Gly/Thr-rich
HgeneNUP98chr11:3744387chr12:54338780ENST00000397007-16207_480732.3333333333334938.0Compositional biasNote=Gly/Thr-rich
HgeneNUP98chr11:3744387chr12:54338780ENST00000324932-16331_156715.33333333333341801.0RegionNote=FG repeats 1
HgeneNUP98chr11:3744387chr12:54338780ENST00000324932-1633214_480715.33333333333341801.0RegionNote=FG repeats 2
HgeneNUP98chr11:3744387chr12:54338780ENST00000355260-16321_156715.33333333333341727.0RegionNote=FG repeats 1
HgeneNUP98chr11:3744387chr12:54338780ENST00000355260-1632214_480715.33333333333341727.0RegionNote=FG repeats 2
HgeneNUP98chr11:3744387chr12:54338780ENST00000397004-16201_156715.3333333333334921.0RegionNote=FG repeats 1
HgeneNUP98chr11:3744387chr12:54338780ENST00000397004-1620214_480715.3333333333334921.0RegionNote=FG repeats 2
HgeneNUP98chr11:3744387chr12:54338780ENST00000397007-16201_156732.3333333333334938.0RegionNote=FG repeats 1
HgeneNUP98chr11:3744387chr12:54338780ENST00000397007-1620214_480732.3333333333334938.0RegionNote=FG repeats 2
TgeneHOXC13chr11:3744387chr12:54338780ENST0000024305602260_319245.33333333333334331.0DNA bindingHomeobox

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNUP98chr11:3744387chr12:54338780ENST00000324932-1633890_894715.33333333333341801.0Compositional biasNote=Poly-Glu
HgeneNUP98chr11:3744387chr12:54338780ENST00000355260-1632890_894715.33333333333341727.0Compositional biasNote=Poly-Glu
HgeneNUP98chr11:3744387chr12:54338780ENST00000397004-1620890_894715.3333333333334921.0Compositional biasNote=Poly-Glu
HgeneNUP98chr11:3744387chr12:54338780ENST00000397007-1620890_894732.3333333333334938.0Compositional biasNote=Poly-Glu
HgeneNUP98chr11:3744387chr12:54338780ENST00000324932-1633738_880715.33333333333341801.0DomainPeptidase S59
HgeneNUP98chr11:3744387chr12:54338780ENST00000355260-1632738_880715.33333333333341727.0DomainPeptidase S59
HgeneNUP98chr11:3744387chr12:54338780ENST00000397004-1620738_880715.3333333333334921.0DomainPeptidase S59
HgeneNUP98chr11:3744387chr12:54338780ENST00000397007-1620738_880732.3333333333334938.0DomainPeptidase S59
TgeneHOXC13chr11:3744387chr12:54338780ENST000002430560227_61245.33333333333334331.0Compositional biasNote=Gly-rich


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Fusion Gene Sequence for NUP98-HOXC13


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000324932_ENST00000243056_AJ438986_NUP98_chr11_3744387_-_HOXC13_chr12_54338780_length(transcript)=4112nt_BP=2567nt
AACCGCGGCGGCGAGGGGCGGGACTCCACGGCCCTCTCACCGCTCCTACCCTGTGCCTCCCCGAACTCCTTCTGCCCCTCCTCTTCCCTC
TCGCCCCTTCCCCCTTCAGTTCGGTTTCAAAAGACGCGTTGCCCAATGAATAACAGGGTCGACCCAGAGTGGCGGCCGCGTCCACCAATT
CGCGGACGGCGAGGGCGGAGCGTCCGCAACGAGCCTCTGACGCCGGGCGGCGTGTGACGCAGTCGGGCCCTCTGCGCGCTGCGCCCGAAG
CGGCGGTCGGTGGCAGGGGTGGTAGCGGCGGCGGCGACGGTTTCGTGGGGGCCGCGCGCTGCTCTGTGAGCGGCGGGTGGCAGCAGGGGA
CTCCTGACACTTCCCCTTCCCCACCGAACCGCGCTTTCTGAAACAAAGACTCATTTTGAAGATGTTTAACAAATCATTTGGAACACCCTT
TGGGGGTGGCACAGGTGGCTTTGGCACAACTTCAACATTTGGACAGAATACTGGCTTTGGCACTACTAGTGGAGGGGCATTTGGAACATC
TGCATTTGGTTCTAGCAACAATACTGGAGGCCTCTTTGGAAATTCACAGACTAAACCAGGAGGATTGTTTGGAACCAGTTCATTTAGCCA
GCCAGCTACCTCCACAAGCACTGGCTTTGGGTTTGGTACGTCAACAGGAACAGCAAATACCTTGTTTGGAACTGCAAGCACAGGGACCAG
TCTCTTCTCATCCCAAAACAATGCCTTTGCACAAAATAAACCAACTGGCTTTGGCAATTTTGGAACCAGTACTAGCAGTGGAGGACTCTT
TGGAACCACAAATACCACCTCTAATCCTTTTGGCAGCACATCTGGCTCCCTCTTTGGGCCAAGTAGTTTTACAGCTGCTCCTACTGGGAC
TACTATTAAATTTAACCCTCCAACTGGTACAGATACTATGGTCAAAGCTGGAGTTAGCACTAACATAAGTACCAAGCACCAGTGTATTAC
TGCTATGAAAGAATATGAAAGCAAGTCACTAGAGGAACTTCGTTTAGAGGATTATCAGGCTAACAGGAAGGGCCCACAGAACCAGGTGGG
AGCAGGTACCACAACTGGCTTGTTTGGGTCTTCTCCAGCCACTTCCAGCGCAACAGGACTCTTCAGCTCCTCCACCACTAATTCAGGCTT
TGCATATGGTCAGAACAAAACTGCCTTTGGAACTAGTACAACTGGATTTGGAACAAATCCAGGTGGTCTCTTTGGCCAACAGAATCAGCA
GACTACCAGCCTCTTCAGCAAACCATTTGGCCAGGCTACAACCACCCAGAACACTGGCTTTTCCTTTGGTAATACCAGCACCATAGGACA
GCCAAGCACCAACACCATGGGATTATTTGGAGTAACCCAAGCCTCACAGCCTGGAGGTCTTTTTGGGACAGCTACAAACACCAGCACTGG
GACAGCATTTGGAACAGGAACAGGTCTCTTTGGGCAGACCAATACTGGATTTGGTGCTGTTGGTTCGACCCTGTTTGGCAATAACAAGCT
TACTACATTTGGAAGCAGCACAACCAGTGCACCTTCATTTGGTACAACCAGTGGCGGGCTCTTTGGTTTTGGCACAAATACCAGTGGGAA
TAGTATTTTTGGAAGTAAACCAGCACCTGGGACTCTTGGAACTGGGCTTGGTGCAGGATTTGGAACAGCTCTTGGTGCTGGACAGGCATC
TTTGTTTGGGAACAACCAACCTAAGATTGGAGGGCCTCTTGGTACAGGAGCCTTTGGGGCCCCTGGATTTAATACTACGACAGCCACTTT
GGGCTTTGGAGCCCCCCAGGCCCCAGTAGCTTTGACAGATCCAAATGCTTCTGCTGCCCAGCAGGCTGTTCTCCAGCAGCACATCAATAG
TCTAACATACTCACCTTTTGGAGACTCTCCTCTCTTCCGGAATCCGATGTCAGACCCTAAGAAGAAGGAAGAGAGATTGAAACCAACAAA
TCCAGCAGCCCAGAAGGCTCTTACTACACCTACTCATTATAAACTGACACCCCGCCCTGCCACTAGAGTCCGGCCAAAGGCTTTACAAAC
AACAGGCACAGCCAAGTCACATCTCTTTGATGGGCTGGATGACGATGAACCATCCCTAGCCAATGGAGCATTCATGCCCAAGAAGAGCAT
TAAGAAGTTGGTTTTGAAGAACCTTAATAATAGCAATCTCTTTTCTCCTGTTAATCGTGATTCAGAAAATCTAGCTTCACCATCTGAATA
TCCAGAAAATGGAGAGAGATTTAGTTTCCTAAGCAAACCTGTTGATGAGAATCACCAGCAGGATGGAGATGAAGATTCCCTTGTTTCACA
TTTTTATACTAACCCTATTGCCAAACCTATTCCTCAAACCCCAGAAAGTGCTGGAAATAAACACAGCAACAGCAACAGTGTGGATGATAC
CATTGTTGCATTAAACATGCGTGCTGCTTTGCGAAATGGGCTGGAAGGAAGCAGTGAAGAAACGTCTTTTCATGATGAGTCACTTCAGGA
TGACCGAGAAGAAATAGAAAATAATTCTTACCATATGCACCCAGCAGACGTGGTTCCCCTGCAGCCCGAGGTGAGCAGCTACCGGCGCGG
GCGCAAGAAACGCGTGCCCTACACTAAGGTGCAGCTGAAGGAGCTAGAGAAGGAATACGCGGCTAGCAAGTTCATCACCAAAGAGAAGCG
CCGGCGCATCTCCGCCACCACGAACCTCTCTGAGCGCCAGGTAACCATCTGGTTCCAGAACCGGCGGGTCAAAGAGAAGAAGGTGGTCAG
CAAATCGAAAGCGCCTCATCTCCACTCCACCTGACCACCCACCCGCTGCTTGCCCCATCTATTTATGTCTCCGCTTTGTACCATAACCGA
ACCCACGGAAAGACGCTGCGCGGGTGCAGAAGAGTATTTAATGTTAAGGAAAGAGAAGAACCGCGCCGCCCGGAGGCAGAGAGGCTCCAT
GGCCGTGCTGCTGGGCCATCCCCAACTCCCTATCCCATCCCCAGCCTCCACCCCCATCCAGATGGGACTCACGTGGCTTCAACAGCTTTG
GAAATGGGTCCCGAGTGGGCCGTGCGAGGAAGGCTGTCGACCTCTACTCCTCCTTGCGCTCACCTTGCCAGAAAGTCTGGTGGCAGCGCA
GAGCCCAATCATTCCAACCAAAGCAGGGTTGGGGAATCCCGAATGGCCCCAATTCTTGCCTCATCCTATGACCAGGCTTTTAGAGGACCT
TCCCTAAGGGCGCAGCTTCGGAGCAGGATCTGTCCAGCTCATACTTTCCTTCGCTGTCCCTCCCGCACTCCTTAGGCAAGATTTCCCAGT
AAAGATTTTCTGTGCGTATTTTAAAAGTCGTGTTAATACTCATGATAATTATTAGGGACCTGGCAGCGTGATTGGAGTATGGATGTTTCC
GTAAAAGCTGGAATTCCGTAAAAGCATTGACGCAGCCCCTACACTCCATCCCAACCAAGAAACTGCATTTCCTGGGGCCAGGTGGGAGCT
GCCTTTGCCCCACTGCCTCCCCTGTTCTGCTCTCTCAGTCAACATGTGGAAATCCAAGGAGGACAAAGACTCCAGCCACGCTGCTAAATA
GGGCTCCTCTCTCCTCTCTCTCTCTCTAGGTGGTAAGGTTGGGGATTAGTCCAGGTACAGAAGCAGAACTTTTTTCTAAGGATAAACATC
TCTTCCAAGGGGATGGAGAGTGGGTCCCTCAACAAAGTCCCTGTCCAGTCACCTTTCCATCAGGGCACTAGCCCAGGAATGACTCCTCAC
ACTTTCACCTTTACTGATTTCCAGAGGAAAGCTAGAGGATCTAGTTCAAGAGGCAAGAAGATCTGGCCCTCAATTAGCTAGATGTAGATG
CTGCCTAACAGTTCCCTCCTCAAAGGCCACCTTGGTGCTGTGGGGGCCCCTTGCCTCTTCCCTTCCCACTGGTGCATTACAAAACAGTGT
TCTTTTGAAATGTTCATCAGGAATAGGCTTTTTTAAAAAATGTTGTGTATCTGTATATAGTATTGTGATGTCTGAATGACAATGTACTGA

>In-frame_ENST00000324932_ENST00000243056_AJ438986_NUP98_chr11_3744387_-_HOXC13_chr12_54338780_length(amino acids)=808AA_start in transcript=397_stop in transcript=2823
MKQRLILKMFNKSFGTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFGFG
TSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDT
MVKAGVSTNISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQNKTAFGTS
TTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQ
TNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGP
LGTGAFGAPGFNTTTATLGFGAPQAPVALTDPNASAAQQAVLQQHINSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNPAAQKALTTPTH
YKLTPRPATRVRPKALQTTGTAKSHLFDGLDDDEPSLANGAFMPKKSIKKLVLKNLNNSNLFSPVNRDSENLASPSEYPENGERFSFLSK
PVDENHQQDGDEDSLVSHFYTNPIAKPIPQTPESAGNKHSNSNSVDDTIVALNMRAALRNGLEGSSEETSFHDESLQDDREEIENNSYHM

--------------------------------------------------------------
>In-frame_ENST00000355260_ENST00000243056_AJ438986_NUP98_chr11_3744387_-_HOXC13_chr12_54338780_length(transcript)=3778nt_BP=2233nt
TGTGAGCGGCGGGTGGCAGCAGGGGACTCCTGACACTTCCCCTTCCCCACCGAACCGCGCTTTCTGAAACAAAGACTCATTTTGAAGATG
TTTAACAAATCATTTGGAACACCCTTTGGGGGTGGCACAGGTGGCTTTGGCACAACTTCAACATTTGGACAGAATACTGGCTTTGGCACT
ACTAGTGGAGGGGCATTTGGAACATCTGCATTTGGTTCTAGCAACAATACTGGAGGCCTCTTTGGAAATTCACAGACTAAACCAGGAGGA
TTGTTTGGAACCAGTTCATTTAGCCAGCCAGCTACCTCCACAAGCACTGGCTTTGGGTTTGGTACGTCAACAGGAACAGCAAATACCTTG
TTTGGAACTGCAAGCACAGGGACCAGTCTCTTCTCATCCCAAAACAATGCCTTTGCACAAAATAAACCAACTGGCTTTGGCAATTTTGGA
ACCAGTACTAGCAGTGGAGGACTCTTTGGAACCACAAATACCACCTCTAATCCTTTTGGCAGCACATCTGGCTCCCTCTTTGGGCCAAGT
AGTTTTACAGCTGCTCCTACTGGGACTACTATTAAATTTAACCCTCCAACTGGTACAGATACTATGGTCAAAGCTGGAGTTAGCACTAAC
ATAAGTACCAAGCACCAGTGTATTACTGCTATGAAAGAATATGAAAGCAAGTCACTAGAGGAACTTCGTTTAGAGGATTATCAGGCTAAC
AGGAAGGGCCCACAGAACCAGGTGGGAGCAGGTACCACAACTGGCTTGTTTGGGTCTTCTCCAGCCACTTCCAGCGCAACAGGACTCTTC
AGCTCCTCCACCACTAATTCAGGCTTTGCATATGGTCAGAACAAAACTGCCTTTGGAACTAGTACAACTGGATTTGGAACAAATCCAGGT
GGTCTCTTTGGCCAACAGAATCAGCAGACTACCAGCCTCTTCAGCAAACCATTTGGCCAGGCTACAACCACCCAGAACACTGGCTTTTCC
TTTGGTAATACCAGCACCATAGGACAGCCAAGCACCAACACCATGGGATTATTTGGAGTAACCCAAGCCTCACAGCCTGGAGGTCTTTTT
GGGACAGCTACAAACACCAGCACTGGGACAGCATTTGGAACAGGAACAGGTCTCTTTGGGCAGACCAATACTGGATTTGGTGCTGTTGGT
TCGACCCTGTTTGGCAATAACAAGCTTACTACATTTGGAAGCAGCACAACCAGTGCACCTTCATTTGGTACAACCAGTGGCGGGCTCTTT
GGTTTTGGCACAAATACCAGTGGGAATAGTATTTTTGGAAGTAAACCAGCACCTGGGACTCTTGGAACTGGGCTTGGTGCAGGATTTGGA
ACAGCTCTTGGTGCTGGACAGGCATCTTTGTTTGGGAACAACCAACCTAAGATTGGAGGGCCTCTTGGTACAGGAGCCTTTGGGGCCCCT
GGATTTAATACTACGACAGCCACTTTGGGCTTTGGAGCCCCCCAGGCCCCAGTAGCTTTGACAGATCCAAATGCTTCTGCTGCCCAGCAG
GCTGTTCTCCAGCAGCACATCAATAGTCTAACATACTCACCTTTTGGAGACTCTCCTCTCTTCCGGAATCCGATGTCAGACCCTAAGAAG
AAGGAAGAGAGATTGAAACCAACAAATCCAGCAGCCCAGAAGGCTCTTACTACACCTACTCATTATAAACTGACACCCCGCCCTGCCACT
AGAGTCCGGCCAAAGGCTTTACAAACAACAGGCACAGCCAAGTCACATCTCTTTGATGGGCTGGATGACGATGAACCATCCCTAGCCAAT
GGAGCATTCATGCCCAAGAAGAGCATTAAGAAGTTGGTTTTGAAGAACCTTAATAATAGCAATCTCTTTTCTCCTGTTAATCGTGATTCA
GAAAATCTAGCTTCACCATCTGAATATCCAGAAAATGGAGAGAGATTTAGTTTCCTAAGCAAACCTGTTGATGAGAATCACCAGCAGGAT
GGAGATGAAGATTCCCTTGTTTCACATTTTTATACTAACCCTATTGCCAAACCTATTCCTCAAACCCCAGAAAGTGCTGGAAATAAACAC
AGCAACAGCAACAGTGTGGATGATACCATTGTTGCATTAAACATGCGTGCTGCTTTGCGAAATGGGCTGGAAGGAAGCAGTGAAGAAACG
TCTTTTCATGATGAGTCACTTCAGGATGACCGAGAAGAAATAGAAAATAATTCTTACCATATGCACCCAGCAGACGTGGTTCCCCTGCAG
CCCGAGGTGAGCAGCTACCGGCGCGGGCGCAAGAAACGCGTGCCCTACACTAAGGTGCAGCTGAAGGAGCTAGAGAAGGAATACGCGGCT
AGCAAGTTCATCACCAAAGAGAAGCGCCGGCGCATCTCCGCCACCACGAACCTCTCTGAGCGCCAGGTAACCATCTGGTTCCAGAACCGG
CGGGTCAAAGAGAAGAAGGTGGTCAGCAAATCGAAAGCGCCTCATCTCCACTCCACCTGACCACCCACCCGCTGCTTGCCCCATCTATTT
ATGTCTCCGCTTTGTACCATAACCGAACCCACGGAAAGACGCTGCGCGGGTGCAGAAGAGTATTTAATGTTAAGGAAAGAGAAGAACCGC
GCCGCCCGGAGGCAGAGAGGCTCCATGGCCGTGCTGCTGGGCCATCCCCAACTCCCTATCCCATCCCCAGCCTCCACCCCCATCCAGATG
GGACTCACGTGGCTTCAACAGCTTTGGAAATGGGTCCCGAGTGGGCCGTGCGAGGAAGGCTGTCGACCTCTACTCCTCCTTGCGCTCACC
TTGCCAGAAAGTCTGGTGGCAGCGCAGAGCCCAATCATTCCAACCAAAGCAGGGTTGGGGAATCCCGAATGGCCCCAATTCTTGCCTCAT
CCTATGACCAGGCTTTTAGAGGACCTTCCCTAAGGGCGCAGCTTCGGAGCAGGATCTGTCCAGCTCATACTTTCCTTCGCTGTCCCTCCC
GCACTCCTTAGGCAAGATTTCCCAGTAAAGATTTTCTGTGCGTATTTTAAAAGTCGTGTTAATACTCATGATAATTATTAGGGACCTGGC
AGCGTGATTGGAGTATGGATGTTTCCGTAAAAGCTGGAATTCCGTAAAAGCATTGACGCAGCCCCTACACTCCATCCCAACCAAGAAACT
GCATTTCCTGGGGCCAGGTGGGAGCTGCCTTTGCCCCACTGCCTCCCCTGTTCTGCTCTCTCAGTCAACATGTGGAAATCCAAGGAGGAC
AAAGACTCCAGCCACGCTGCTAAATAGGGCTCCTCTCTCCTCTCTCTCTCTCTAGGTGGTAAGGTTGGGGATTAGTCCAGGTACAGAAGC
AGAACTTTTTTCTAAGGATAAACATCTCTTCCAAGGGGATGGAGAGTGGGTCCCTCAACAAAGTCCCTGTCCAGTCACCTTTCCATCAGG
GCACTAGCCCAGGAATGACTCCTCACACTTTCACCTTTACTGATTTCCAGAGGAAAGCTAGAGGATCTAGTTCAAGAGGCAAGAAGATCT
GGCCCTCAATTAGCTAGATGTAGATGCTGCCTAACAGTTCCCTCCTCAAAGGCCACCTTGGTGCTGTGGGGGCCCCTTGCCTCTTCCCTT
CCCACTGGTGCATTACAAAACAGTGTTCTTTTGAAATGTTCATCAGGAATAGGCTTTTTTAAAAAATGTTGTGTATCTGTATATAGTATT

>In-frame_ENST00000355260_ENST00000243056_AJ438986_NUP98_chr11_3744387_-_HOXC13_chr12_54338780_length(amino acids)=808AA_start in transcript=63_stop in transcript=2489
MKQRLILKMFNKSFGTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFGFG
TSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDT
MVKAGVSTNISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQNKTAFGTS
TTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQ
TNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGP
LGTGAFGAPGFNTTTATLGFGAPQAPVALTDPNASAAQQAVLQQHINSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNPAAQKALTTPTH
YKLTPRPATRVRPKALQTTGTAKSHLFDGLDDDEPSLANGAFMPKKSIKKLVLKNLNNSNLFSPVNRDSENLASPSEYPENGERFSFLSK
PVDENHQQDGDEDSLVSHFYTNPIAKPIPQTPESAGNKHSNSNSVDDTIVALNMRAALRNGLEGSSEETSFHDESLQDDREEIENNSYHM

--------------------------------------------------------------
>In-frame_ENST00000397004_ENST00000243056_AJ438986_NUP98_chr11_3744387_-_HOXC13_chr12_54338780_length(transcript)=3861nt_BP=2316nt
CTGCGCGCTGCGCCCGAAGCGGCGGTCGGTGGCAGGGGTGGTAGCGGCGGCGGCGACGGTTTCGTGGGGGCCGCGCGCTGCTCTGTGAGC
GGCGGGTGGCAGCAGGGGACTCCTGACACTTCCCCTTCCCCACCGAACCGCGCTTTCTGAAACAAAGACTCATTTTGAAGATGTTTAACA
AATCATTTGGAACACCCTTTGGGGGTGGCACAGGTGGCTTTGGCACAACTTCAACATTTGGACAGAATACTGGCTTTGGCACTACTAGTG
GAGGGGCATTTGGAACATCTGCATTTGGTTCTAGCAACAATACTGGAGGCCTCTTTGGAAATTCACAGACTAAACCAGGAGGATTGTTTG
GAACCAGTTCATTTAGCCAGCCAGCTACCTCCACAAGCACTGGCTTTGGGTTTGGTACGTCAACAGGAACAGCAAATACCTTGTTTGGAA
CTGCAAGCACAGGGACCAGTCTCTTCTCATCCCAAAACAATGCCTTTGCACAAAATAAACCAACTGGCTTTGGCAATTTTGGAACCAGTA
CTAGCAGTGGAGGACTCTTTGGAACCACAAATACCACCTCTAATCCTTTTGGCAGCACATCTGGCTCCCTCTTTGGGCCAAGTAGTTTTA
CAGCTGCTCCTACTGGGACTACTATTAAATTTAACCCTCCAACTGGTACAGATACTATGGTCAAAGCTGGAGTTAGCACTAACATAAGTA
CCAAGCACCAGTGTATTACTGCTATGAAAGAATATGAAAGCAAGTCACTAGAGGAACTTCGTTTAGAGGATTATCAGGCTAACAGGAAGG
GCCCACAGAACCAGGTGGGAGCAGGTACCACAACTGGCTTGTTTGGGTCTTCTCCAGCCACTTCCAGCGCAACAGGACTCTTCAGCTCCT
CCACCACTAATTCAGGCTTTGCATATGGTCAGAACAAAACTGCCTTTGGAACTAGTACAACTGGATTTGGAACAAATCCAGGTGGTCTCT
TTGGCCAACAGAATCAGCAGACTACCAGCCTCTTCAGCAAACCATTTGGCCAGGCTACAACCACCCAGAACACTGGCTTTTCCTTTGGTA
ATACCAGCACCATAGGACAGCCAAGCACCAACACCATGGGATTATTTGGAGTAACCCAAGCCTCACAGCCTGGAGGTCTTTTTGGGACAG
CTACAAACACCAGCACTGGGACAGCATTTGGAACAGGAACAGGTCTCTTTGGGCAGACCAATACTGGATTTGGTGCTGTTGGTTCGACCC
TGTTTGGCAATAACAAGCTTACTACATTTGGAAGCAGCACAACCAGTGCACCTTCATTTGGTACAACCAGTGGCGGGCTCTTTGGTTTTG
GCACAAATACCAGTGGGAATAGTATTTTTGGAAGTAAACCAGCACCTGGGACTCTTGGAACTGGGCTTGGTGCAGGATTTGGAACAGCTC
TTGGTGCTGGACAGGCATCTTTGTTTGGGAACAACCAACCTAAGATTGGAGGGCCTCTTGGTACAGGAGCCTTTGGGGCCCCTGGATTTA
ATACTACGACAGCCACTTTGGGCTTTGGAGCCCCCCAGGCCCCAGTAGCTTTGACAGATCCAAATGCTTCTGCTGCCCAGCAGGCTGTTC
TCCAGCAGCACATCAATAGTCTAACATACTCACCTTTTGGAGACTCTCCTCTCTTCCGGAATCCGATGTCAGACCCTAAGAAGAAGGAAG
AGAGATTGAAACCAACAAATCCAGCAGCCCAGAAGGCTCTTACTACACCTACTCATTATAAACTGACACCCCGCCCTGCCACTAGAGTCC
GGCCAAAGGCTTTACAAACAACAGGCACAGCCAAGTCACATCTCTTTGATGGGCTGGATGACGATGAACCATCCCTAGCCAATGGAGCAT
TCATGCCCAAGAAGAGCATTAAGAAGTTGGTTTTGAAGAACCTTAATAATAGCAATCTCTTTTCTCCTGTTAATCGTGATTCAGAAAATC
TAGCTTCACCATCTGAATATCCAGAAAATGGAGAGAGATTTAGTTTCCTAAGCAAACCTGTTGATGAGAATCACCAGCAGGATGGAGATG
AAGATTCCCTTGTTTCACATTTTTATACTAACCCTATTGCCAAACCTATTCCTCAAACCCCAGAAAGTGCTGGAAATAAACACAGCAACA
GCAACAGTGTGGATGATACCATTGTTGCATTAAACATGCGTGCTGCTTTGCGAAATGGGCTGGAAGGAAGCAGTGAAGAAACGTCTTTTC
ATGATGAGTCACTTCAGGATGACCGAGAAGAAATAGAAAATAATTCTTACCATATGCACCCAGCAGACGTGGTTCCCCTGCAGCCCGAGG
TGAGCAGCTACCGGCGCGGGCGCAAGAAACGCGTGCCCTACACTAAGGTGCAGCTGAAGGAGCTAGAGAAGGAATACGCGGCTAGCAAGT
TCATCACCAAAGAGAAGCGCCGGCGCATCTCCGCCACCACGAACCTCTCTGAGCGCCAGGTAACCATCTGGTTCCAGAACCGGCGGGTCA
AAGAGAAGAAGGTGGTCAGCAAATCGAAAGCGCCTCATCTCCACTCCACCTGACCACCCACCCGCTGCTTGCCCCATCTATTTATGTCTC
CGCTTTGTACCATAACCGAACCCACGGAAAGACGCTGCGCGGGTGCAGAAGAGTATTTAATGTTAAGGAAAGAGAAGAACCGCGCCGCCC
GGAGGCAGAGAGGCTCCATGGCCGTGCTGCTGGGCCATCCCCAACTCCCTATCCCATCCCCAGCCTCCACCCCCATCCAGATGGGACTCA
CGTGGCTTCAACAGCTTTGGAAATGGGTCCCGAGTGGGCCGTGCGAGGAAGGCTGTCGACCTCTACTCCTCCTTGCGCTCACCTTGCCAG
AAAGTCTGGTGGCAGCGCAGAGCCCAATCATTCCAACCAAAGCAGGGTTGGGGAATCCCGAATGGCCCCAATTCTTGCCTCATCCTATGA
CCAGGCTTTTAGAGGACCTTCCCTAAGGGCGCAGCTTCGGAGCAGGATCTGTCCAGCTCATACTTTCCTTCGCTGTCCCTCCCGCACTCC
TTAGGCAAGATTTCCCAGTAAAGATTTTCTGTGCGTATTTTAAAAGTCGTGTTAATACTCATGATAATTATTAGGGACCTGGCAGCGTGA
TTGGAGTATGGATGTTTCCGTAAAAGCTGGAATTCCGTAAAAGCATTGACGCAGCCCCTACACTCCATCCCAACCAAGAAACTGCATTTC
CTGGGGCCAGGTGGGAGCTGCCTTTGCCCCACTGCCTCCCCTGTTCTGCTCTCTCAGTCAACATGTGGAAATCCAAGGAGGACAAAGACT
CCAGCCACGCTGCTAAATAGGGCTCCTCTCTCCTCTCTCTCTCTCTAGGTGGTAAGGTTGGGGATTAGTCCAGGTACAGAAGCAGAACTT
TTTTCTAAGGATAAACATCTCTTCCAAGGGGATGGAGAGTGGGTCCCTCAACAAAGTCCCTGTCCAGTCACCTTTCCATCAGGGCACTAG
CCCAGGAATGACTCCTCACACTTTCACCTTTACTGATTTCCAGAGGAAAGCTAGAGGATCTAGTTCAAGAGGCAAGAAGATCTGGCCCTC
AATTAGCTAGATGTAGATGCTGCCTAACAGTTCCCTCCTCAAAGGCCACCTTGGTGCTGTGGGGGCCCCTTGCCTCTTCCCTTCCCACTG
GTGCATTACAAAACAGTGTTCTTTTGAAATGTTCATCAGGAATAGGCTTTTTTAAAAAATGTTGTGTATCTGTATATAGTATTGTGATGT

>In-frame_ENST00000397004_ENST00000243056_AJ438986_NUP98_chr11_3744387_-_HOXC13_chr12_54338780_length(amino acids)=808AA_start in transcript=146_stop in transcript=2572
MKQRLILKMFNKSFGTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFGFG
TSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDT
MVKAGVSTNISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQNKTAFGTS
TTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQ
TNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGP
LGTGAFGAPGFNTTTATLGFGAPQAPVALTDPNASAAQQAVLQQHINSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNPAAQKALTTPTH
YKLTPRPATRVRPKALQTTGTAKSHLFDGLDDDEPSLANGAFMPKKSIKKLVLKNLNNSNLFSPVNRDSENLASPSEYPENGERFSFLSK
PVDENHQQDGDEDSLVSHFYTNPIAKPIPQTPESAGNKHSNSNSVDDTIVALNMRAALRNGLEGSSEETSFHDESLQDDREEIENNSYHM

--------------------------------------------------------------
>In-frame_ENST00000397007_ENST00000243056_AJ438986_NUP98_chr11_3744387_-_HOXC13_chr12_54338780_length(transcript)=3918nt_BP=2373nt
GGCCCTCTGCGCGCTGCGCCCGAAGCGGCGGTCGGTGGCAGGGGTGGTAGCGGCGGCGGCGACGGTTTCGTGGGGGCCGCGCGCTGCTCT
GTGAGCGGCGGGTGGCAGCAGGGGACTCCTGACACTTCCCCTTCCCCACCGAACCGCGCTTTCTGAAACAAAGACTCATTTTGAAGATGT
TTAACAAATCATTTGGAACACCCTTTGGGGGTGGCACAGGTGGCTTTGGCACAACTTCAACATTTGGACAGAATACTGGCTTTGGCACTA
CTAGTGGAGGGGCATTTGGAACATCTGCATTTGGTTCTAGCAACAATACTGGAGGCCTCTTTGGAAATTCACAGACTAAACCAGGAGGAT
TGTTTGGAACCAGTTCATTTAGCCAGCCAGCTACCTCCACAAGCACTGGCTTTGGGTTTGGTACGTCAACAGGAACAGCAAATACCTTGT
TTGGAACTGCAAGCACAGGGACCAGTCTCTTCTCATCCCAAAACAATGCCTTTGCACAAAATAAACCAACTGGCTTTGGCAATTTTGGAA
CCAGTACTAGCAGTGGAGGACTCTTTGGAACCACAAATACCACCTCTAATCCTTTTGGCAGCACATCTGGCTCCCTCTTTGGGCCAAGTA
GTTTTACAGCTGCTCCTACTGGGACTACTATTAAATTTAACCCTCCAACTGGTACAGATACTATGGTCAAAGCTGGAGTTAGCACTAACA
TAAGTACCAAGCACCAGTGTATTACTGCTATGAAAGAATATGAAAGCAAGTCACTAGAGGAACTTCGTTTAGAGGATTATCAGGCTAACA
GGAAGGGCCCACAGAACCAGGTGGGAGCAGGTACCACAACTGGCTTGTTTGGGTCTTCTCCAGCCACTTCCAGCGCAACAGGACTCTTCA
GCTCCTCCACCACTAATTCAGGCTTTGCATATGGTCAGAACAAAACTGCCTTTGGAACTAGTACAACTGGATTTGGAACAAATCCAGGTG
GTCTCTTTGGCCAACAGAATCAGCAGACTACCAGCCTCTTCAGCAAACCATTTGGCCAGGCTACAACCACCCAGAACACTGGCTTTTCCT
TTGGTAATACCAGCACCATAGGACAGCCAAGCACCAACACCATGGGATTATTTGGAGTAACCCAAGCCTCACAGCCTGGAGGTCTTTTTG
GGACAGCTACAAACACCAGCACTGGGACAGCATTTGGAACAGGAACAGGTCTCTTTGGGCAGACCAATACTGGATTTGGTGCTGTTGGTT
CGACCCTGTTTGGCAATAACAAGCTTACTACATTTGGAAGCAGCACAACCAGTGCACCTTCATTTGGTACAACCAGTGGCGGGCTCTTTG
GTAACAAACCAACCCTGACTTTAGGAACCAATACAAACACTTCTAATTTTGGTTTTGGCACAAATACCAGTGGGAATAGTATTTTTGGAA
GTAAACCAGCACCTGGGACTCTTGGAACTGGGCTTGGTGCAGGATTTGGAACAGCTCTTGGTGCTGGACAGGCATCTTTGTTTGGGAACA
ACCAACCTAAGATTGGAGGGCCTCTTGGTACAGGAGCCTTTGGGGCCCCTGGATTTAATACTACGACAGCCACTTTGGGCTTTGGAGCCC
CCCAGGCCCCAGTAGCTTTGACAGATCCAAATGCTTCTGCTGCCCAGCAGGCTGTTCTCCAGCAGCACATCAATAGTCTAACATACTCAC
CTTTTGGAGACTCTCCTCTCTTCCGGAATCCGATGTCAGACCCTAAGAAGAAGGAAGAGAGATTGAAACCAACAAATCCAGCAGCCCAGA
AGGCTCTTACTACACCTACTCATTATAAACTGACACCCCGCCCTGCCACTAGAGTCCGGCCAAAGGCTTTACAAACAACAGGCACAGCCA
AGTCACATCTCTTTGATGGGCTGGATGACGATGAACCATCCCTAGCCAATGGAGCATTCATGCCCAAGAAGAGCATTAAGAAGTTGGTTT
TGAAGAACCTTAATAATAGCAATCTCTTTTCTCCTGTTAATCGTGATTCAGAAAATCTAGCTTCACCATCTGAATATCCAGAAAATGGAG
AGAGATTTAGTTTCCTAAGCAAACCTGTTGATGAGAATCACCAGCAGGATGGAGATGAAGATTCCCTTGTTTCACATTTTTATACTAACC
CTATTGCCAAACCTATTCCTCAAACCCCAGAAAGTGCTGGAAATAAACACAGCAACAGCAACAGTGTGGATGATACCATTGTTGCATTAA
ACATGCGTGCTGCTTTGCGAAATGGGCTGGAAGGAAGCAGTGAAGAAACGTCTTTTCATGATGAGTCACTTCAGGATGACCGAGAAGAAA
TAGAAAATAATTCTTACCATATGCACCCAGCAGACGTGGTTCCCCTGCAGCCCGAGGTGAGCAGCTACCGGCGCGGGCGCAAGAAACGCG
TGCCCTACACTAAGGTGCAGCTGAAGGAGCTAGAGAAGGAATACGCGGCTAGCAAGTTCATCACCAAAGAGAAGCGCCGGCGCATCTCCG
CCACCACGAACCTCTCTGAGCGCCAGGTAACCATCTGGTTCCAGAACCGGCGGGTCAAAGAGAAGAAGGTGGTCAGCAAATCGAAAGCGC
CTCATCTCCACTCCACCTGACCACCCACCCGCTGCTTGCCCCATCTATTTATGTCTCCGCTTTGTACCATAACCGAACCCACGGAAAGAC
GCTGCGCGGGTGCAGAAGAGTATTTAATGTTAAGGAAAGAGAAGAACCGCGCCGCCCGGAGGCAGAGAGGCTCCATGGCCGTGCTGCTGG
GCCATCCCCAACTCCCTATCCCATCCCCAGCCTCCACCCCCATCCAGATGGGACTCACGTGGCTTCAACAGCTTTGGAAATGGGTCCCGA
GTGGGCCGTGCGAGGAAGGCTGTCGACCTCTACTCCTCCTTGCGCTCACCTTGCCAGAAAGTCTGGTGGCAGCGCAGAGCCCAATCATTC
CAACCAAAGCAGGGTTGGGGAATCCCGAATGGCCCCAATTCTTGCCTCATCCTATGACCAGGCTTTTAGAGGACCTTCCCTAAGGGCGCA
GCTTCGGAGCAGGATCTGTCCAGCTCATACTTTCCTTCGCTGTCCCTCCCGCACTCCTTAGGCAAGATTTCCCAGTAAAGATTTTCTGTG
CGTATTTTAAAAGTCGTGTTAATACTCATGATAATTATTAGGGACCTGGCAGCGTGATTGGAGTATGGATGTTTCCGTAAAAGCTGGAAT
TCCGTAAAAGCATTGACGCAGCCCCTACACTCCATCCCAACCAAGAAACTGCATTTCCTGGGGCCAGGTGGGAGCTGCCTTTGCCCCACT
GCCTCCCCTGTTCTGCTCTCTCAGTCAACATGTGGAAATCCAAGGAGGACAAAGACTCCAGCCACGCTGCTAAATAGGGCTCCTCTCTCC
TCTCTCTCTCTCTAGGTGGTAAGGTTGGGGATTAGTCCAGGTACAGAAGCAGAACTTTTTTCTAAGGATAAACATCTCTTCCAAGGGGAT
GGAGAGTGGGTCCCTCAACAAAGTCCCTGTCCAGTCACCTTTCCATCAGGGCACTAGCCCAGGAATGACTCCTCACACTTTCACCTTTAC
TGATTTCCAGAGGAAAGCTAGAGGATCTAGTTCAAGAGGCAAGAAGATCTGGCCCTCAATTAGCTAGATGTAGATGCTGCCTAACAGTTC
CCTCCTCAAAGGCCACCTTGGTGCTGTGGGGGCCCCTTGCCTCTTCCCTTCCCACTGGTGCATTACAAAACAGTGTTCTTTTGAAATGTT
CATCAGGAATAGGCTTTTTTAAAAAATGTTGTGTATCTGTATATAGTATTGTGATGTCTGAATGACAATGTACTGAATGCAAAAAGGAAA

>In-frame_ENST00000397007_ENST00000243056_AJ438986_NUP98_chr11_3744387_-_HOXC13_chr12_54338780_length(amino acids)=825AA_start in transcript=152_stop in transcript=2629
MKQRLILKMFNKSFGTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFGFG
TSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDT
MVKAGVSTNISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQNKTAFGTS
TTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQ
TNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFGTALG
AGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGFGAPQAPVALTDPNASAAQQAVLQQHINSLTYSPFGDSPLFRNPMSDPKKKEER
LKPTNPAAQKALTTPTHYKLTPRPATRVRPKALQTTGTAKSHLFDGLDDDEPSLANGAFMPKKSIKKLVLKNLNNSNLFSPVNRDSENLA
SPSEYPENGERFSFLSKPVDENHQQDGDEDSLVSHFYTNPIAKPIPQTPESAGNKHSNSNSVDDTIVALNMRAALRNGLEGSSEETSFHD
ESLQDDREEIENNSYHMHPADVVPLQPEVSSYRRGRKKRVPYTKVQLKELEKEYAASKFITKEKRRRISATTNLSERQVTIWFQNRRVKE

--------------------------------------------------------------

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Fusion Gene PPI Analysis for NUP98-HOXC13


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for NUP98-HOXC13


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for NUP98-HOXC13


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneNUP98C0002871Anemia1CTD_human
HgeneNUP98C0023467Leukemia, Myelocytic, Acute1CTD_human
HgeneNUP98C0024312Lymphopenia1CTD_human
HgeneNUP98C0026998Acute Myeloid Leukemia, M11CTD_human
HgeneNUP98C0027947Neutropenia1CTD_human
HgeneNUP98C1879321Acute Myeloid Leukemia (AML-M2)1CTD_human
HgeneNUP98C2930974Acute erythroleukemia1CTD_human
HgeneNUP98C2930975Acute erythroleukemia - M6a subtype1CTD_human
HgeneNUP98C2930976Acute myeloid leukemia FAB-M61CTD_human
HgeneNUP98C2930977Acute erythroleukemia - M6b subtype1CTD_human
TgeneHOXC13C1865951Ectodermal Dysplasia, Pure Hair-Nail Type2CTD_human;ORPHANET
TgeneHOXC13C3554127ECTODERMAL DYSPLASIA 9, HAIR/NAIL TYPE2CTD_human;GENOMICS_ENGLAND;UNIPROT