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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:NXN-ABR (FusionGDB2 ID:60821)

Fusion Gene Summary for NXN-ABR

check button Fusion gene summary
Fusion gene informationFusion gene name: NXN-ABR
Fusion gene ID: 60821
HgeneTgene
Gene symbol

NXN

ABR

Gene ID

64359

29

Gene namenucleoredoxinABR activator of RhoGEF and GTPase
SynonymsNRX|RRS2|TRG-4MDB
Cytomap

17p13.3

17p13.3

Type of geneprotein-codingprotein-coding
Descriptionnucleoredoxinnucleoredoxin 1active breakpoint cluster region-related proteinABR, RhoGEF and GTPase activating proteinactive BCR-related
Modification date2020032720200313
UniProtAcc.

Q15018

Ensembl transtripts involved in fusion geneENST00000336868, ENST00000577098, 
ENST00000575801, ENST00000538650, 
ENST00000537628, 		ENST00000302538, 
ENST00000544583, ENST00000572441, 
ENST00000574437, ENST00000291107, 
ENST00000543210, ENST00000536794, 
ENST00000573895, 
Fusion gene scores* DoF score16 X 13 X 11=228817 X 14 X 9=2142
# samples 2321
** MAII scorelog2(23/2288*10)=-3.31438128583401
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(21/2142*10)=-3.35049724708413
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: NXN [Title/Abstract] AND ABR [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointNXN(882559)-ABR(916404), # samples:5
ABR(953290)-NXN(729318), # samples:2
Anticipated loss of major functional domain due to fusion event.ABR-NXN seems lost the major protein functional domain in Hgene partner, which is a kinase due to the frame-shifted ORF.
ABR-NXN seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneABR

GO:0090630

activation of GTPase activity

7479768


check buttonFusion gene breakpoints across NXN (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across ABR (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-E9-A22G-01ANXNchr17

882559

-ABRchr17

916404

-
ChimerDB4CESCTCGA-EK-A2RO-01ANXNchr17

882559

-ABRchr17

916404

-
ChimerDB4CESCTCGA-MY-A913-01ANXNchr17

882559

-ABRchr17

916404

-
ChimerDB4LUADTCGA-55-8506-01ANXNchr17

882559

-ABRchr17

962107

-
ChimerDB4LUADTCGA-55-8506-01ANXNchr17

882559

-ABRchr17

962107

-
ChimerDB4CESCTCGA-EK-A2RO-01ANXNchr17

882559

-ABRchr17

916404

-
ChimerDB4CESCTCGA-MY-A913-01ANXNchr17

882559

-ABRchr17

916404

-


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Fusion Gene ORF analysis for NXN-ABR

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000336868ENST00000302538NXNchr17

882559

-ABRchr17

916404

-
In-frameENST00000336868ENST00000544583NXNchr17

882559

-ABRchr17

916404

-
In-frameENST00000336868ENST00000572441NXNchr17

882559

-ABRchr17

916404

-
In-frameENST00000336868ENST00000574437NXNchr17

882559

-ABRchr17

916404

-
In-frameENST00000336868ENST00000291107NXNchr17

882559

-ABRchr17

916404

-
In-frameENST00000336868ENST00000543210NXNchr17

882559

-ABRchr17

916404

-
In-frameENST00000336868ENST00000536794NXNchr17

882559

-ABRchr17

916404

-
5CDS-intronENST00000336868ENST00000573895NXNchr17

882559

-ABRchr17

916404

-
intron-3CDSENST00000577098ENST00000302538NXNchr17

882559

-ABRchr17

916404

-
intron-3CDSENST00000577098ENST00000544583NXNchr17

882559

-ABRchr17

916404

-
intron-3CDSENST00000577098ENST00000572441NXNchr17

882559

-ABRchr17

916404

-
intron-3CDSENST00000577098ENST00000574437NXNchr17

882559

-ABRchr17

916404

-
intron-3CDSENST00000577098ENST00000291107NXNchr17

882559

-ABRchr17

916404

-
intron-3CDSENST00000577098ENST00000543210NXNchr17

882559

-ABRchr17

916404

-
intron-3CDSENST00000577098ENST00000536794NXNchr17

882559

-ABRchr17

916404

-
intron-intronENST00000577098ENST00000573895NXNchr17

882559

-ABRchr17

916404

-
intron-3CDSENST00000575801ENST00000302538NXNchr17

882559

-ABRchr17

916404

-
intron-3CDSENST00000575801ENST00000544583NXNchr17

882559

-ABRchr17

916404

-
intron-3CDSENST00000575801ENST00000572441NXNchr17

882559

-ABRchr17

916404

-
intron-3CDSENST00000575801ENST00000574437NXNchr17

882559

-ABRchr17

916404

-
intron-3CDSENST00000575801ENST00000291107NXNchr17

882559

-ABRchr17

916404

-
intron-3CDSENST00000575801ENST00000543210NXNchr17

882559

-ABRchr17

916404

-
intron-3CDSENST00000575801ENST00000536794NXNchr17

882559

-ABRchr17

916404

-
intron-intronENST00000575801ENST00000573895NXNchr17

882559

-ABRchr17

916404

-
intron-3CDSENST00000538650ENST00000302538NXNchr17

882559

-ABRchr17

916404

-
intron-3CDSENST00000538650ENST00000544583NXNchr17

882559

-ABRchr17

916404

-
intron-3CDSENST00000538650ENST00000572441NXNchr17

882559

-ABRchr17

916404

-
intron-3CDSENST00000538650ENST00000574437NXNchr17

882559

-ABRchr17

916404

-
intron-3CDSENST00000538650ENST00000291107NXNchr17

882559

-ABRchr17

916404

-
intron-3CDSENST00000538650ENST00000543210NXNchr17

882559

-ABRchr17

916404

-
intron-3CDSENST00000538650ENST00000536794NXNchr17

882559

-ABRchr17

916404

-
intron-intronENST00000538650ENST00000573895NXNchr17

882559

-ABRchr17

916404

-
intron-3CDSENST00000537628ENST00000302538NXNchr17

882559

-ABRchr17

916404

-
intron-3CDSENST00000537628ENST00000544583NXNchr17

882559

-ABRchr17

916404

-
intron-3CDSENST00000537628ENST00000572441NXNchr17

882559

-ABRchr17

916404

-
intron-3CDSENST00000537628ENST00000574437NXNchr17

882559

-ABRchr17

916404

-
intron-3CDSENST00000537628ENST00000291107NXNchr17

882559

-ABRchr17

916404

-
intron-3CDSENST00000537628ENST00000543210NXNchr17

882559

-ABRchr17

916404

-
intron-3CDSENST00000537628ENST00000536794NXNchr17

882559

-ABRchr17

916404

-
intron-intronENST00000537628ENST00000573895NXNchr17

882559

-ABRchr17

916404

-
In-frameENST00000336868ENST00000302538NXNchr17

882559

-ABRchr17

962107

-
In-frameENST00000336868ENST00000544583NXNchr17

882559

-ABRchr17

962107

-
5CDS-intronENST00000336868ENST00000572441NXNchr17

882559

-ABRchr17

962107

-
5CDS-intronENST00000336868ENST00000574437NXNchr17

882559

-ABRchr17

962107

-
5CDS-intronENST00000336868ENST00000291107NXNchr17

882559

-ABRchr17

962107

-
5CDS-intronENST00000336868ENST00000543210NXNchr17

882559

-ABRchr17

962107

-
5CDS-intronENST00000336868ENST00000536794NXNchr17

882559

-ABRchr17

962107

-
5CDS-intronENST00000336868ENST00000573895NXNchr17

882559

-ABRchr17

962107

-
intron-3CDSENST00000577098ENST00000302538NXNchr17

882559

-ABRchr17

962107

-
intron-3CDSENST00000577098ENST00000544583NXNchr17

882559

-ABRchr17

962107

-
intron-intronENST00000577098ENST00000572441NXNchr17

882559

-ABRchr17

962107

-
intron-intronENST00000577098ENST00000574437NXNchr17

882559

-ABRchr17

962107

-
intron-intronENST00000577098ENST00000291107NXNchr17

882559

-ABRchr17

962107

-
intron-intronENST00000577098ENST00000543210NXNchr17

882559

-ABRchr17

962107

-
intron-intronENST00000577098ENST00000536794NXNchr17

882559

-ABRchr17

962107

-
intron-intronENST00000577098ENST00000573895NXNchr17

882559

-ABRchr17

962107

-
intron-3CDSENST00000575801ENST00000302538NXNchr17

882559

-ABRchr17

962107

-
intron-3CDSENST00000575801ENST00000544583NXNchr17

882559

-ABRchr17

962107

-
intron-intronENST00000575801ENST00000572441NXNchr17

882559

-ABRchr17

962107

-
intron-intronENST00000575801ENST00000574437NXNchr17

882559

-ABRchr17

962107

-
intron-intronENST00000575801ENST00000291107NXNchr17

882559

-ABRchr17

962107

-
intron-intronENST00000575801ENST00000543210NXNchr17

882559

-ABRchr17

962107

-
intron-intronENST00000575801ENST00000536794NXNchr17

882559

-ABRchr17

962107

-
intron-intronENST00000575801ENST00000573895NXNchr17

882559

-ABRchr17

962107

-
intron-3CDSENST00000538650ENST00000302538NXNchr17

882559

-ABRchr17

962107

-
intron-3CDSENST00000538650ENST00000544583NXNchr17

882559

-ABRchr17

962107

-
intron-intronENST00000538650ENST00000572441NXNchr17

882559

-ABRchr17

962107

-
intron-intronENST00000538650ENST00000574437NXNchr17

882559

-ABRchr17

962107

-
intron-intronENST00000538650ENST00000291107NXNchr17

882559

-ABRchr17

962107

-
intron-intronENST00000538650ENST00000543210NXNchr17

882559

-ABRchr17

962107

-
intron-intronENST00000538650ENST00000536794NXNchr17

882559

-ABRchr17

962107

-
intron-intronENST00000538650ENST00000573895NXNchr17

882559

-ABRchr17

962107

-
intron-3CDSENST00000537628ENST00000302538NXNchr17

882559

-ABRchr17

962107

-
intron-3CDSENST00000537628ENST00000544583NXNchr17

882559

-ABRchr17

962107

-
intron-intronENST00000537628ENST00000572441NXNchr17

882559

-ABRchr17

962107

-
intron-intronENST00000537628ENST00000574437NXNchr17

882559

-ABRchr17

962107

-
intron-intronENST00000537628ENST00000291107NXNchr17

882559

-ABRchr17

962107

-
intron-intronENST00000537628ENST00000543210NXNchr17

882559

-ABRchr17

962107

-
intron-intronENST00000537628ENST00000536794NXNchr17

882559

-ABRchr17

962107

-
intron-intronENST00000537628ENST00000573895NXNchr17

882559

-ABRchr17

962107

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score

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Fusion Genomic Features for NXN-ABR


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for NXN-ABR


check button Go to

FGviewer for the breakpoints of chr17:882559-chr17:916404

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.ABR

Q15018

FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Component of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked polyubiquitin, leaving the last ubiquitin chain attached to its substrates (PubMed:19214193, PubMed:20032457, PubMed:20656690, PubMed:24075985). May act as a central scaffold protein that assembles the various components of the BRISC complex and retains them in the cytoplasm (PubMed:20656690). Plays a role in regulating the onset of apoptosis via its role in modulating 'Lys-63'-linked ubiquitination of target proteins (By similarity). Required for normal mitotic spindle assembly and microtubule attachment to kinetochores via its role in deubiquitinating NUMA1 (PubMed:26195665). Plays a role in interferon signaling via its role in the deubiquitination of the interferon receptor IFNAR1; deubiquitination increases IFNAR1 activities by enhancing its stability and cell surface expression (PubMed:24075985, PubMed:26344097). Down-regulates the response to bacterial lipopolysaccharide (LPS) via its role in IFNAR1 deubiquitination (PubMed:24075985). Required for normal induction of p53/TP53 in response to DNA damage (PubMed:25283148). Independent of the BRISC complex, promotes interaction between USP7 and p53/TP53, and thereby promotes deubiquitination of p53/TP53, preventing its degradation and resulting in increased p53/TP53-mediated transcription regulation and p53/TP53-dependent apoptosis in response to DNA damage (PubMed:25283148). {ECO:0000250|UniProtKB:Q3TCJ1, ECO:0000269|PubMed:19214193, ECO:0000269|PubMed:20032457, ECO:0000269|PubMed:20656690, ECO:0000269|PubMed:24075985, ECO:0000269|PubMed:25283148}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneABRchr17:882559chr17:916404ENST0000054321008417_42048.0311.0Compositional biasNote=Poly-Leu
TgeneABRchr17:882559chr17:962107ENST00000291107822417_420357.0823.0Compositional biasNote=Poly-Leu
TgeneABRchr17:882559chr17:962107ENST00000302538923417_420394.0860.0Compositional biasNote=Poly-Leu
TgeneABRchr17:882559chr17:962107ENST0000054321008417_4200311.0Compositional biasNote=Poly-Leu
TgeneABRchr17:882559chr17:962107ENST00000544583923417_420348.0814.0Compositional biasNote=Poly-Leu
TgeneABRchr17:882559chr17:962107ENST00000574437822417_420348.0814.0Compositional biasNote=Poly-Leu
TgeneABRchr17:882559chr17:916404ENST000002911071422647_845560.0823.0DomainRho-GAP
TgeneABRchr17:882559chr17:916404ENST000003025381523647_845597.0860.0DomainRho-GAP
TgeneABRchr17:882559chr17:916404ENST0000054321008301_45948.0311.0DomainPH
TgeneABRchr17:882559chr17:916404ENST0000054321008484_61348.0311.0DomainC2
TgeneABRchr17:882559chr17:916404ENST0000054321008647_84548.0311.0DomainRho-GAP
TgeneABRchr17:882559chr17:916404ENST000005432100891_28448.0311.0DomainDH
TgeneABRchr17:882559chr17:916404ENST000005445831523647_845551.0814.0DomainRho-GAP
TgeneABRchr17:882559chr17:916404ENST000005744371422647_845551.0814.0DomainRho-GAP
TgeneABRchr17:882559chr17:962107ENST00000291107822484_613357.0823.0DomainC2
TgeneABRchr17:882559chr17:962107ENST00000291107822647_845357.0823.0DomainRho-GAP
TgeneABRchr17:882559chr17:962107ENST00000302538923484_613394.0860.0DomainC2
TgeneABRchr17:882559chr17:962107ENST00000302538923647_845394.0860.0DomainRho-GAP
TgeneABRchr17:882559chr17:962107ENST0000054321008301_4590311.0DomainPH
TgeneABRchr17:882559chr17:962107ENST0000054321008484_6130311.0DomainC2
TgeneABRchr17:882559chr17:962107ENST0000054321008647_8450311.0DomainRho-GAP
TgeneABRchr17:882559chr17:962107ENST000005432100891_2840311.0DomainDH
TgeneABRchr17:882559chr17:962107ENST00000544583923484_613348.0814.0DomainC2
TgeneABRchr17:882559chr17:962107ENST00000544583923647_845348.0814.0DomainRho-GAP
TgeneABRchr17:882559chr17:962107ENST00000574437822484_613348.0814.0DomainC2
TgeneABRchr17:882559chr17:962107ENST00000574437822647_845348.0814.0DomainRho-GAP

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNXNchr17:882559chr17:916404ENST00000336868-18167_321120.0436.0DomainThioredoxin
HgeneNXNchr17:882559chr17:916404ENST00000537628-18167_3210187.0DomainThioredoxin
HgeneNXNchr17:882559chr17:916404ENST00000575801-18167_3210328.0DomainThioredoxin
HgeneNXNchr17:882559chr17:962107ENST00000336868-18167_321120.0436.0DomainThioredoxin
HgeneNXNchr17:882559chr17:962107ENST00000537628-18167_3210187.0DomainThioredoxin
HgeneNXNchr17:882559chr17:962107ENST00000575801-18167_3210328.0DomainThioredoxin
TgeneABRchr17:882559chr17:916404ENST000002911071422417_420560.0823.0Compositional biasNote=Poly-Leu
TgeneABRchr17:882559chr17:916404ENST000003025381523417_420597.0860.0Compositional biasNote=Poly-Leu
TgeneABRchr17:882559chr17:916404ENST000005445831523417_420551.0814.0Compositional biasNote=Poly-Leu
TgeneABRchr17:882559chr17:916404ENST000005744371422417_420551.0814.0Compositional biasNote=Poly-Leu
TgeneABRchr17:882559chr17:916404ENST000002911071422301_459560.0823.0DomainPH
TgeneABRchr17:882559chr17:916404ENST000002911071422484_613560.0823.0DomainC2
TgeneABRchr17:882559chr17:916404ENST00000291107142291_284560.0823.0DomainDH
TgeneABRchr17:882559chr17:916404ENST000003025381523301_459597.0860.0DomainPH
TgeneABRchr17:882559chr17:916404ENST000003025381523484_613597.0860.0DomainC2
TgeneABRchr17:882559chr17:916404ENST00000302538152391_284597.0860.0DomainDH
TgeneABRchr17:882559chr17:916404ENST000005445831523301_459551.0814.0DomainPH
TgeneABRchr17:882559chr17:916404ENST000005445831523484_613551.0814.0DomainC2
TgeneABRchr17:882559chr17:916404ENST00000544583152391_284551.0814.0DomainDH
TgeneABRchr17:882559chr17:916404ENST000005744371422301_459551.0814.0DomainPH
TgeneABRchr17:882559chr17:916404ENST000005744371422484_613551.0814.0DomainC2
TgeneABRchr17:882559chr17:916404ENST00000574437142291_284551.0814.0DomainDH
TgeneABRchr17:882559chr17:962107ENST00000291107822301_459357.0823.0DomainPH
TgeneABRchr17:882559chr17:962107ENST0000029110782291_284357.0823.0DomainDH
TgeneABRchr17:882559chr17:962107ENST00000302538923301_459394.0860.0DomainPH
TgeneABRchr17:882559chr17:962107ENST0000030253892391_284394.0860.0DomainDH
TgeneABRchr17:882559chr17:962107ENST00000544583923301_459348.0814.0DomainPH
TgeneABRchr17:882559chr17:962107ENST0000054458392391_284348.0814.0DomainDH
TgeneABRchr17:882559chr17:962107ENST00000574437822301_459348.0814.0DomainPH
TgeneABRchr17:882559chr17:962107ENST0000057443782291_284348.0814.0DomainDH


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Fusion Gene Sequence for NXN-ABR


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

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Fusion Gene PPI Analysis for NXN-ABR


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for NXN-ABR


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for NXN-ABR


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneNXNC0009402Colorectal Carcinoma1CTD_human
HgeneNXNC0009404Colorectal Neoplasms1CTD_human
HgeneNXNC1849334Robinow syndrome, autosomal recessive1ORPHANET
TgeneABRC0033578Prostatic Neoplasms1CTD_human
TgeneABRC0376358Malignant neoplasm of prostate1CTD_human