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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:OXSR1-DAXX (FusionGDB2 ID:61659)

Fusion Gene Summary for OXSR1-DAXX

check button Fusion gene summary
Fusion gene informationFusion gene name: OXSR1-DAXX
Fusion gene ID: 61659
HgeneTgene
Gene symbol

OXSR1

DAXX

Gene ID

9943

1616

Gene nameoxidative stress responsive kinase 1death domain associated protein
SynonymsOSR1BING2|DAP6|EAP1|SMIM40
Cytomap

3p22.2

6p21.32

Type of geneprotein-codingprotein-coding
Descriptionserine/threonine-protein kinase OSR1oxidative stress responsive 1oxidative stress-responsive 1 proteindeath domain-associated protein 6CENP-C binding proteinETS1-associated protein 1Fas-binding proteindeath-associated protein 6fas death domain-associated protein
Modification date2020031320200313
UniProtAcc.

Q9UER7

Ensembl transtripts involved in fusion geneENST00000446845, ENST00000311806, 
ENST00000492714, 		ENST00000266000, 
ENST00000374542, ENST00000414083, 
ENST00000477162, ENST00000455860, 
ENST00000436311, ENST00000472399, 
ENST00000399060, ENST00000383062, 
ENST00000461796, ENST00000433482, 
ENST00000445009, ENST00000469277, 
ENST00000399344, ENST00000383194, 
ENST00000494562, ENST00000414388, 
Fusion gene scores* DoF score9 X 10 X 8=7207 X 4 X 5=140
# samples 127
** MAII scorelog2(12/720*10)=-2.58496250072116
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(7/140*10)=-1
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: OXSR1 [Title/Abstract] AND DAXX [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointOXSR1(38294368)-DAXX(33286940), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneOXSR1

GO:0006468

protein phosphorylation

14707132

HgeneOXSR1

GO:0018107

peptidyl-threonine phosphorylation

24393035

HgeneOXSR1

GO:0035556

intracellular signal transduction

14707132

HgeneOXSR1

GO:0046777

protein autophosphorylation

22052202

TgeneDAXX

GO:0006334

nucleosome assembly

20504901|20651253

TgeneDAXX

GO:0006338

chromatin remodeling

20651253

TgeneDAXX

GO:0006355

regulation of transcription, DNA-templated

15878163

TgeneDAXX

GO:0030521

androgen receptor signaling pathway

15572661

TgeneDAXX

GO:0031396

regulation of protein ubiquitination

18566590

TgeneDAXX

GO:0034605

cellular response to heat

15016915

TgeneDAXX

GO:0034620

cellular response to unfolded protein

15016915

TgeneDAXX

GO:0045892

negative regulation of transcription, DNA-templated

12140263|15572661

TgeneDAXX

GO:0071276

cellular response to cadmium ion

15016915

TgeneDAXX

GO:0071280

cellular response to copper ion

15016915

TgeneDAXX

GO:0072738

cellular response to diamide

15016915

TgeneDAXX

GO:1903936

cellular response to sodium arsenite

15016915


check buttonFusion gene breakpoints across OXSR1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across DAXX (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChiTaRS5.0N/ABG114042OXSR1chr3

38294368

+DAXXchr6

33286940

-


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Fusion Gene ORF analysis for OXSR1-DAXX

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
intron-3CDSENST00000446845ENST00000266000OXSR1chr3

38294368

+DAXXchr6

33286940

-
intron-3CDSENST00000446845ENST00000374542OXSR1chr3

38294368

+DAXXchr6

33286940

-
intron-3CDSENST00000446845ENST00000414083OXSR1chr3

38294368

+DAXXchr6

33286940

-
intron-intronENST00000446845ENST00000477162OXSR1chr3

38294368

+DAXXchr6

33286940

-
intron-intronENST00000446845ENST00000455860OXSR1chr3

38294368

+DAXXchr6

33286940

-
intron-intronENST00000446845ENST00000436311OXSR1chr3

38294368

+DAXXchr6

33286940

-
intron-intronENST00000446845ENST00000472399OXSR1chr3

38294368

+DAXXchr6

33286940

-
intron-intronENST00000446845ENST00000399060OXSR1chr3

38294368

+DAXXchr6

33286940

-
intron-intronENST00000446845ENST00000383062OXSR1chr3

38294368

+DAXXchr6

33286940

-
intron-intronENST00000446845ENST00000461796OXSR1chr3

38294368

+DAXXchr6

33286940

-
intron-intronENST00000446845ENST00000433482OXSR1chr3

38294368

+DAXXchr6

33286940

-
intron-intronENST00000446845ENST00000445009OXSR1chr3

38294368

+DAXXchr6

33286940

-
intron-intronENST00000446845ENST00000469277OXSR1chr3

38294368

+DAXXchr6

33286940

-
intron-intronENST00000446845ENST00000399344OXSR1chr3

38294368

+DAXXchr6

33286940

-
intron-intronENST00000446845ENST00000383194OXSR1chr3

38294368

+DAXXchr6

33286940

-
intron-intronENST00000446845ENST00000494562OXSR1chr3

38294368

+DAXXchr6

33286940

-
intron-intronENST00000446845ENST00000414388OXSR1chr3

38294368

+DAXXchr6

33286940

-
In-frameENST00000311806ENST00000266000OXSR1chr3

38294368

+DAXXchr6

33286940

-
In-frameENST00000311806ENST00000374542OXSR1chr3

38294368

+DAXXchr6

33286940

-
In-frameENST00000311806ENST00000414083OXSR1chr3

38294368

+DAXXchr6

33286940

-
5CDS-intronENST00000311806ENST00000477162OXSR1chr3

38294368

+DAXXchr6

33286940

-
5CDS-intronENST00000311806ENST00000455860OXSR1chr3

38294368

+DAXXchr6

33286940

-
5CDS-intronENST00000311806ENST00000436311OXSR1chr3

38294368

+DAXXchr6

33286940

-
5CDS-intronENST00000311806ENST00000472399OXSR1chr3

38294368

+DAXXchr6

33286940

-
5CDS-intronENST00000311806ENST00000399060OXSR1chr3

38294368

+DAXXchr6

33286940

-
5CDS-intronENST00000311806ENST00000383062OXSR1chr3

38294368

+DAXXchr6

33286940

-
5CDS-intronENST00000311806ENST00000461796OXSR1chr3

38294368

+DAXXchr6

33286940

-
5CDS-intronENST00000311806ENST00000433482OXSR1chr3

38294368

+DAXXchr6

33286940

-
5CDS-intronENST00000311806ENST00000445009OXSR1chr3

38294368

+DAXXchr6

33286940

-
5CDS-intronENST00000311806ENST00000469277OXSR1chr3

38294368

+DAXXchr6

33286940

-
5CDS-intronENST00000311806ENST00000399344OXSR1chr3

38294368

+DAXXchr6

33286940

-
5CDS-intronENST00000311806ENST00000383194OXSR1chr3

38294368

+DAXXchr6

33286940

-
5CDS-intronENST00000311806ENST00000494562OXSR1chr3

38294368

+DAXXchr6

33286940

-
5CDS-intronENST00000311806ENST00000414388OXSR1chr3

38294368

+DAXXchr6

33286940

-
intron-3CDSENST00000492714ENST00000266000OXSR1chr3

38294368

+DAXXchr6

33286940

-
intron-3CDSENST00000492714ENST00000374542OXSR1chr3

38294368

+DAXXchr6

33286940

-
intron-3CDSENST00000492714ENST00000414083OXSR1chr3

38294368

+DAXXchr6

33286940

-
intron-intronENST00000492714ENST00000477162OXSR1chr3

38294368

+DAXXchr6

33286940

-
intron-intronENST00000492714ENST00000455860OXSR1chr3

38294368

+DAXXchr6

33286940

-
intron-intronENST00000492714ENST00000436311OXSR1chr3

38294368

+DAXXchr6

33286940

-
intron-intronENST00000492714ENST00000472399OXSR1chr3

38294368

+DAXXchr6

33286940

-
intron-intronENST00000492714ENST00000399060OXSR1chr3

38294368

+DAXXchr6

33286940

-
intron-intronENST00000492714ENST00000383062OXSR1chr3

38294368

+DAXXchr6

33286940

-
intron-intronENST00000492714ENST00000461796OXSR1chr3

38294368

+DAXXchr6

33286940

-
intron-intronENST00000492714ENST00000433482OXSR1chr3

38294368

+DAXXchr6

33286940

-
intron-intronENST00000492714ENST00000445009OXSR1chr3

38294368

+DAXXchr6

33286940

-
intron-intronENST00000492714ENST00000469277OXSR1chr3

38294368

+DAXXchr6

33286940

-
intron-intronENST00000492714ENST00000399344OXSR1chr3

38294368

+DAXXchr6

33286940

-
intron-intronENST00000492714ENST00000383194OXSR1chr3

38294368

+DAXXchr6

33286940

-
intron-intronENST00000492714ENST00000494562OXSR1chr3

38294368

+DAXXchr6

33286940

-
intron-intronENST00000492714ENST00000414388OXSR1chr3

38294368

+DAXXchr6

33286940

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000311806OXSR1chr338294368+ENST00000266000DAXXchr633286940-490444922012084627
ENST00000311806OXSR1chr338294368+ENST00000374542DAXXchr633286940-490444922012084627
ENST00000311806OXSR1chr338294368+ENST00000414083DAXXchr633286940-474344922012084627

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000311806ENST00000266000OXSR1chr338294368+DAXXchr633286940-0.000508080.99949193
ENST00000311806ENST00000374542OXSR1chr338294368+DAXXchr633286940-0.000508080.99949193
ENST00000311806ENST00000414083OXSR1chr338294368+DAXXchr633286940-0.0006360450.99936396

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Fusion Genomic Features for OXSR1-DAXX


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for OXSR1-DAXX


check button Go to

FGviewer for the breakpoints of chr3:38294368-chr6:33286940

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.DAXX

Q9UER7

FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Transcription corepressor known to repress transcriptional potential of several sumoylated transcription factors. Down-regulates basal and activated transcription. Its transcription repressor activity is modulated by recruiting it to subnuclear compartments like the nucleolus or PML/POD/ND10 nuclear bodies through interactions with MCSR1 and PML, respectively. Seems to regulate transcription in PML/POD/ND10 nuclear bodies together with PML and may influence TNFRSF6-dependent apoptosis thereby. Inhibits transcriptional activation of PAX3 and ETS1 through direct protein-protein interactions. Modulates PAX5 activity; the function seems to involve CREBBP. Acts as an adapter protein in a MDM2-DAXX-USP7 complex by regulating the RING-finger E3 ligase MDM2 ubiquitination activity. Under non-stress condition, in association with the deubiquitinating USP7, prevents MDM2 self-ubiquitination and enhances the intrinsic E3 ligase activity of MDM2 towards TP53, thereby promoting TP53 ubiquitination and subsequent proteasomal degradation. Upon DNA damage, its association with MDM2 and USP7 is disrupted, resulting in increased MDM2 autoubiquitination and consequently, MDM2 degradation, which leads to TP53 stabilization. Acts as histone chaperone that facilitates deposition of histone H3.3. Acts as targeting component of the chromatin remodeling complex ATRX:DAXX which has ATP-dependent DNA translocase activity and catalyzes the replication-independent deposition of histone H3.3 in pericentric DNA repeats outside S-phase and telomeres, and the in vitro remodeling of H3.3-containing nucleosomes. Does not affect the ATPase activity of ATRX but alleviates its transcription repression activity. Upon neuronal activation associates with regulatory elements of selected immediate early genes where it promotes deposition of histone H3.3 which may be linked to transcriptional induction of these genes. Required for the recruitment of histone H3.3:H4 dimers to PML-nuclear bodies (PML-NBs); the process is independent of ATRX and facilitated by ASF1A; PML-NBs are suggested to function as regulatory sites for the incorporation of newly synthesized histone H3.3 into chromatin. In case of overexpression of centromeric histone variant CENPA (as found in various tumors) is involved in its mislocalization to chromosomes; the ectopic localization involves a heterotypic tetramer containing CENPA, and histones H3.3 and H4 and decreases binding of CTCF to chromatin. Proposed to mediate activation of the JNK pathway and apoptosis via MAP3K5 in response to signaling from TNFRSF6 and TGFBR2. Interaction with HSPB1/HSP27 may prevent interaction with TNFRSF6 and MAP3K5 and block DAXX-mediated apoptosis. In contrast, in lymphoid cells JNC activation and TNFRSF6-mediated apoptosis may not involve DAXX. Shows restriction activity towards human cytomegalovirus (HCMV). Plays a role as a positive regulator of the heat shock transcription factor HSF1 activity during the stress protein response (PubMed:15016915). {ECO:0000269|PubMed:12140263, ECO:0000269|PubMed:14990586, ECO:0000269|PubMed:15016915, ECO:0000269|PubMed:15364927, ECO:0000269|PubMed:16845383, ECO:0000269|PubMed:17081986, ECO:0000269|PubMed:17942542, ECO:0000269|PubMed:20504901, ECO:0000269|PubMed:20651253, ECO:0000269|PubMed:23222847, ECO:0000269|PubMed:24200965, ECO:0000269|PubMed:24530302}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneDAXXchr3:38294368chr6:33286940ENST0000026600008180_2170741.0Coiled coilOntology_term=ECO:0000255
TgeneDAXXchr3:38294368chr6:33286940ENST0000026600008358_3990741.0Coiled coilOntology_term=ECO:0000255
TgeneDAXXchr3:38294368chr6:33286940ENST0000026600008430_4890741.0Coiled coilOntology_term=ECO:0000255
TgeneDAXXchr3:38294368chr6:33286940ENST0000037454208180_2170741.0Coiled coilOntology_term=ECO:0000255
TgeneDAXXchr3:38294368chr6:33286940ENST0000037454208358_3990741.0Coiled coilOntology_term=ECO:0000255
TgeneDAXXchr3:38294368chr6:33286940ENST0000037454208430_4890741.0Coiled coilOntology_term=ECO:0000255
TgeneDAXXchr3:38294368chr6:33286940ENST0000038306208180_2170741.0Coiled coilOntology_term=ECO:0000255
TgeneDAXXchr3:38294368chr6:33286940ENST0000038306208358_3990741.0Coiled coilOntology_term=ECO:0000255
TgeneDAXXchr3:38294368chr6:33286940ENST0000038306208430_4890741.0Coiled coilOntology_term=ECO:0000255
TgeneDAXXchr3:38294368chr6:33286940ENST0000038319408180_2170741.0Coiled coilOntology_term=ECO:0000255
TgeneDAXXchr3:38294368chr6:33286940ENST0000038319408358_3990741.0Coiled coilOntology_term=ECO:0000255
TgeneDAXXchr3:38294368chr6:33286940ENST0000038319408430_4890741.0Coiled coilOntology_term=ECO:0000255
TgeneDAXXchr3:38294368chr6:33286940ENST0000039906008180_2170741.0Coiled coilOntology_term=ECO:0000255
TgeneDAXXchr3:38294368chr6:33286940ENST0000039906008358_3990741.0Coiled coilOntology_term=ECO:0000255
TgeneDAXXchr3:38294368chr6:33286940ENST0000039906008430_4890741.0Coiled coilOntology_term=ECO:0000255
TgeneDAXXchr3:38294368chr6:33286940ENST0000039934408180_2170741.0Coiled coilOntology_term=ECO:0000255
TgeneDAXXchr3:38294368chr6:33286940ENST0000039934408358_3990741.0Coiled coilOntology_term=ECO:0000255
TgeneDAXXchr3:38294368chr6:33286940ENST0000039934408430_4890741.0Coiled coilOntology_term=ECO:0000255
TgeneDAXXchr3:38294368chr6:33286940ENST0000041408307180_2170666.0Coiled coilOntology_term=ECO:0000255
TgeneDAXXchr3:38294368chr6:33286940ENST0000041408307358_3990666.0Coiled coilOntology_term=ECO:0000255
TgeneDAXXchr3:38294368chr6:33286940ENST0000041408307430_4890666.0Coiled coilOntology_term=ECO:0000255
TgeneDAXXchr3:38294368chr6:33286940ENST0000043348208180_2170741.0Coiled coilOntology_term=ECO:0000255
TgeneDAXXchr3:38294368chr6:33286940ENST0000043348208358_3990741.0Coiled coilOntology_term=ECO:0000255
TgeneDAXXchr3:38294368chr6:33286940ENST0000043348208430_4890741.0Coiled coilOntology_term=ECO:0000255
TgeneDAXXchr3:38294368chr6:33286940ENST0000043631108180_2170741.0Coiled coilOntology_term=ECO:0000255
TgeneDAXXchr3:38294368chr6:33286940ENST0000043631108358_3990741.0Coiled coilOntology_term=ECO:0000255
TgeneDAXXchr3:38294368chr6:33286940ENST0000043631108430_4890741.0Coiled coilOntology_term=ECO:0000255
TgeneDAXXchr3:38294368chr6:33286940ENST0000044500908180_2170741.0Coiled coilOntology_term=ECO:0000255
TgeneDAXXchr3:38294368chr6:33286940ENST0000044500908358_3990741.0Coiled coilOntology_term=ECO:0000255
TgeneDAXXchr3:38294368chr6:33286940ENST0000044500908430_4890741.0Coiled coilOntology_term=ECO:0000255
TgeneDAXXchr3:38294368chr6:33286940ENST0000045586008180_2170741.0Coiled coilOntology_term=ECO:0000255
TgeneDAXXchr3:38294368chr6:33286940ENST0000045586008358_3990741.0Coiled coilOntology_term=ECO:0000255
TgeneDAXXchr3:38294368chr6:33286940ENST0000045586008430_4890741.0Coiled coilOntology_term=ECO:0000255
TgeneDAXXchr3:38294368chr6:33286940ENST000002660000811_160741.0Compositional biasNote=Poly-Asp
TgeneDAXXchr3:38294368chr6:33286940ENST0000026600008434_5720741.0Compositional biasNote=Asp/Glu-rich (acidic)
TgeneDAXXchr3:38294368chr6:33286940ENST000003745420811_160741.0Compositional biasNote=Poly-Asp
TgeneDAXXchr3:38294368chr6:33286940ENST0000037454208434_5720741.0Compositional biasNote=Asp/Glu-rich (acidic)
TgeneDAXXchr3:38294368chr6:33286940ENST000003830620811_160741.0Compositional biasNote=Poly-Asp
TgeneDAXXchr3:38294368chr6:33286940ENST0000038306208434_5720741.0Compositional biasNote=Asp/Glu-rich (acidic)
TgeneDAXXchr3:38294368chr6:33286940ENST000003831940811_160741.0Compositional biasNote=Poly-Asp
TgeneDAXXchr3:38294368chr6:33286940ENST0000038319408434_5720741.0Compositional biasNote=Asp/Glu-rich (acidic)
TgeneDAXXchr3:38294368chr6:33286940ENST000003990600811_160741.0Compositional biasNote=Poly-Asp
TgeneDAXXchr3:38294368chr6:33286940ENST0000039906008434_5720741.0Compositional biasNote=Asp/Glu-rich (acidic)
TgeneDAXXchr3:38294368chr6:33286940ENST000003993440811_160741.0Compositional biasNote=Poly-Asp
TgeneDAXXchr3:38294368chr6:33286940ENST0000039934408434_5720741.0Compositional biasNote=Asp/Glu-rich (acidic)
TgeneDAXXchr3:38294368chr6:33286940ENST000004140830711_160666.0Compositional biasNote=Poly-Asp
TgeneDAXXchr3:38294368chr6:33286940ENST0000041408307434_5720666.0Compositional biasNote=Asp/Glu-rich (acidic)
TgeneDAXXchr3:38294368chr6:33286940ENST000004334820811_160741.0Compositional biasNote=Poly-Asp
TgeneDAXXchr3:38294368chr6:33286940ENST0000043348208434_5720741.0Compositional biasNote=Asp/Glu-rich (acidic)
TgeneDAXXchr3:38294368chr6:33286940ENST000004363110811_160741.0Compositional biasNote=Poly-Asp
TgeneDAXXchr3:38294368chr6:33286940ENST0000043631108434_5720741.0Compositional biasNote=Asp/Glu-rich (acidic)
TgeneDAXXchr3:38294368chr6:33286940ENST000004450090811_160741.0Compositional biasNote=Poly-Asp
TgeneDAXXchr3:38294368chr6:33286940ENST0000044500908434_5720741.0Compositional biasNote=Asp/Glu-rich (acidic)
TgeneDAXXchr3:38294368chr6:33286940ENST000004558600811_160741.0Compositional biasNote=Poly-Asp
TgeneDAXXchr3:38294368chr6:33286940ENST0000045586008434_5720741.0Compositional biasNote=Asp/Glu-rich (acidic)
TgeneDAXXchr3:38294368chr6:33286940ENST0000026600008391_3950741.0MotifNuclear localization signal
TgeneDAXXchr3:38294368chr6:33286940ENST0000026600008628_6340741.0MotifNuclear localization signal
TgeneDAXXchr3:38294368chr6:33286940ENST0000037454208391_3950741.0MotifNuclear localization signal
TgeneDAXXchr3:38294368chr6:33286940ENST0000037454208628_6340741.0MotifNuclear localization signal
TgeneDAXXchr3:38294368chr6:33286940ENST0000038306208391_3950741.0MotifNuclear localization signal
TgeneDAXXchr3:38294368chr6:33286940ENST0000038306208628_6340741.0MotifNuclear localization signal
TgeneDAXXchr3:38294368chr6:33286940ENST0000038319408391_3950741.0MotifNuclear localization signal
TgeneDAXXchr3:38294368chr6:33286940ENST0000038319408628_6340741.0MotifNuclear localization signal
TgeneDAXXchr3:38294368chr6:33286940ENST0000039906008391_3950741.0MotifNuclear localization signal
TgeneDAXXchr3:38294368chr6:33286940ENST0000039906008628_6340741.0MotifNuclear localization signal
TgeneDAXXchr3:38294368chr6:33286940ENST0000039934408391_3950741.0MotifNuclear localization signal
TgeneDAXXchr3:38294368chr6:33286940ENST0000039934408628_6340741.0MotifNuclear localization signal
TgeneDAXXchr3:38294368chr6:33286940ENST0000041408307391_3950666.0MotifNuclear localization signal
TgeneDAXXchr3:38294368chr6:33286940ENST0000041408307628_6340666.0MotifNuclear localization signal
TgeneDAXXchr3:38294368chr6:33286940ENST0000043348208391_3950741.0MotifNuclear localization signal
TgeneDAXXchr3:38294368chr6:33286940ENST0000043348208628_6340741.0MotifNuclear localization signal
TgeneDAXXchr3:38294368chr6:33286940ENST0000043631108391_3950741.0MotifNuclear localization signal
TgeneDAXXchr3:38294368chr6:33286940ENST0000043631108628_6340741.0MotifNuclear localization signal
TgeneDAXXchr3:38294368chr6:33286940ENST0000044500908391_3950741.0MotifNuclear localization signal
TgeneDAXXchr3:38294368chr6:33286940ENST0000044500908628_6340741.0MotifNuclear localization signal
TgeneDAXXchr3:38294368chr6:33286940ENST0000045586008391_3950741.0MotifNuclear localization signal
TgeneDAXXchr3:38294368chr6:33286940ENST0000045586008628_6340741.0MotifNuclear localization signal

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneOXSR1chr3:38294368chr6:33286940ENST00000311806+11817_2910528.0DomainProtein kinase
HgeneOXSR1chr3:38294368chr6:33286940ENST00000311806+11823_310528.0Nucleotide bindingATP


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Fusion Gene Sequence for OXSR1-DAXX


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000311806_ENST00000266000_BG114042_OXSR1_chr3_38294368_+_DAXX_chr6_33286940_length(transcript)=4904nt_BP=4492nt
GTGTCGGCAGGTGGAGGAAGAGGGGAAAGTTTGGCCCGTGCGTGGGGCTGGGGTGGAGGGCGGGACAGAGGGGCTGGGCCCAGGCAAAGC
TTCTGTCGCTGCTGCTGCGGAGGCCGAGGACAGGACGTGGGCTGGGCCGGGCAGTGCCGGACTCGGAGGAGCAGGAGGCGAGGTCCGCCG
GAGCTCTGAGCCCCCGCTGCTCTGCCGCGCGGTGACCCCGCGCCCCGGCGCCGTCCGACCCGTGGCTGTTCCGAGACGATTGGTGGGGGC
GCGGCGGCGGCGGCGGCGGCTGTTGGGGGTGGGGAGACGCGCGGCGAGGAGACGAGCGAGGTCAGCGAGTTTGAGGGAGGACCGCGAGCC
GCTGCCGCCGTCATGTCCGAGGACTCGAGCGCCCTGCCCTGGTCCATCAACAGGGACGATTACGAGCTGCAGGAGGTGATCGGGAGTGGA
GCAACTGCTGTAGTCCAAGCAGCTTATTGTGCCCCTAAAAAGGAGAAAGTGGCAATCAAACGGATAAACCTTGAGAAATGTCAAACTAGC
ATGGATGAACTCCTGAAAGAAATTCAAGCCATGAGTCAATGCCATCATCCTAATATTGTATCTTACTACACATCTTTTGTGGTAAAAGAT
GAGCTGTGGCTTGTCATGAAGCTGCTAAGTGGAGGTTCTGTTCTGGATATTATTAAGCACATTGTGGCAAAAGGGGAACACAAAAGTGGA
GTCCTAGATGAATCTACCATTGCTACGATACTCCGAGAAGTACTGGAAGGGCTGGAATATCTGCATAAAAATGGACAGATCCACAGAGAT
GTGAAAGCTGGAAACATTCTTCTTGGAGAAGATGGCTCAGTACAGATTGCAGACTTTGGGGTTAGTGCTTTTTTAGCAACTGGTGGTGAT
ATTACCCGAAATAAAGTGAGAAAGACCTTTGTTGGCACCCCTTGTTGGATGGCACCTGAAGTTATGGAACAGGTCCGTGGTTATGATTTC
AAAGCTGATATTTGGAGTTTTGGAATTACAGCAATTGAATTGGCTACAGGGGCGGCTCCTTATCATAAATATCCACCAATGAAGGTTTTA
ATGCTGACACTGCAGAACGATCCTCCTTCTTTGGAAACTGGTGTTCAAGATAAAGAAATGCTGAAAAAATATGGAAAATCATTTAGAAAA
ATGATTTCATTGTGCCTTCAAAAAGATCCAGAAAAAAGACCAACAGCAGCAGAACTATTAAGGCACAAATTTTTCCAGAAAGCAAAGAAT
AAAGAATTTCTTCAAGAAAAAACATTGCAGAGAGCACCAACCATTTCTGAAAGAGCAAAAAAGGTTCGGAGAGTACCAGGTTCCAGTGGG
CGTCTTCATAAGACAGAGGATGGAGGCTGGGAGTGGAGTGATGATGAATTTGATGAAGAAAGTGAGGAAGGGAAAGCAGCAATTTCACAA
CTCAGGTCTCCCCGAGTGAAAGAATCAATATCAAATTCTGAGCTCTTTCCAACAACTGATCCTGTGGGTACTTTGCTCCAAGTTCCAGAA
CAGATCTCTGCTCATCTACCTCAGCCAGCTGGGCAGATTGCTACACAGCCAACTCAAGTCTCTCTCCCACCCACCGCAGAGCCAGCAAAA
ACAGCTCAGGCTTTGTCTTCAGGATCAGGTTCACAAGAAACCAAGATCCCAATCAGTCTAGTACTAAGATTAAGGAATTCCAAAAAAGAA
CTAAATGATATTCGATTTGAATTTACTCCTGGGAGAGATACAGCAGAGGGTGTCTCTCAGGAACTCATTTCTGCTGGCCTGGTCGACGGA
AGGGATTTAGTAATAGTGGCAGCTAATTTGCAGAAAATTGTGGAAGAACCTCAGTCAAATCGATCTGTCACTTTCAAACTGTCAGCATCA
GCTAAACCACAACCCTGGAAGAGGCGGCCTAAGGAGATTCCACACATGCGTATCTCTGTTGCTTCTATTGGCCTAAACCCACTACTGCCA
AAGAACCCAGCAACAAACCTCCCGGCTAGGAGCTTTAGAAGTCTTTATGTTCTTCCTGCCATCATTCCTCCTTTTCCCACAGGGAAAGAA
AAGTTGGATCACTAGTGGCCAGCATCCCCAGAGTTCCGTTAGTAAACTTACTTCATATGTCCCCTGTCTTCCTCCATCTGAGAAGTGGCC
CATGTGCTTCAAGGCCCAGGAGGGAGATCTGTCAGCTCATTCTTGCCTTACTCCAATGATGGCCCAGGTGGAAAAGTAGCAGCTGTATCG
GGCTTCCTCATCCTGCCTGTTCCCCCACACCTGCCAGGATATGGACATCTTGGGATATCTCTTTACCACTGAAGTAGAATTGATTGTTCA
GCTGGAGCCCAGAGAATTTAATTTAATGTTTTTTCTTTGTACCTGATGTGAATTCTAGCAACCTTTGTTAGGAAAAAGCACAGCCTCAGA
TGGAGGCAGCCTAAACTGTGTTCTTGTTTTGTTCATGGTGTTTCTAAGCGTTTTGCTGAAGCTGCTCTCAGGCACCCCCTTCTTCATTGC
TCTCTCCAGAAAGGGTTGCTAGCCTTAACTTCAGCTGGTGCAAAACATCTGACTGTAGCCGAACTTCAGCCATCAGATCCTTCAAAGTGG
AACTTTGGATTGTTTTTACAGACAACATCGAGTAATGGCTTGTAAATGTGAATTTTGCCAGAGGTGGTTTTTGAACAGGAAAATCATAAT
TCATATCATTGGAGAAGTATTTATTTTCAAATATCAAATTGAAGAAAAACTCAATCCTCCCATGAAAATCAGTTCGCCTGGCCTCCAAGT
CGTGAGGAAATGGGTATGCAAGGCTGAGATTTCTACAGCAATAAAGGAGACACACACTGGGCCAGAGAGGCCTGCCTTCTGCCTGCTCTC
CTGCACTGACCCTTTGGAGGGGGTCTCTGTGTGCTGAAGCTAACTCAAGATGGAAAGTGAAACCACATGTGCCGTGACCTTTAGGTTTTA
TGAGTAGACAGTGTTCATTTGATTTTCTACAGAAATAATATAAATTATTCTTTAGGTTTAAAAAAGAGCACTCATAATGCAATATGTGAA
TAATCAGTGAGGTTGATTTTTCTTTTTTCCTACCGTTTCATAGTCTTTGTCTAACTGCTAGTAACCCTACCGAGTTTTATATATGAGTGG
GATACTCAATCTGGCCTTAAAAAGATACACAAAGATGGGCTGTGGGTCCCTGGAAAGGGGGAGAGTTGCCCTTTACAGAATCACTCGAGC
CCTTTCCAGCACTGTTGGTCTGATGAACAAGGTTGTTTTACCTTATTTTCTCTTGGAACATATCTGAAAACCTTCCCCACAAATAACTTG
TCACACCTTTTGTTTCATTCTGAGTCTTTAGTTTTAGTCATGGGCTTTCTTCACCTGCTCTAGGTGCAAAGGCATGTTGGGAAAGAGATG
GATGTTGGGGAGGAAGAGAGGAGATGGATTTCAGTTGGGAGTTAGGAGGAGAGTAGGTGAGATGATCAGACACCGGAGTTCAACGTCCCA
GCAGTCTTGGTAAAAGGAGGGAGCCTGCTGAGCCAGGAGGGAGAAAAGAAGATTGACCAGCTTGCTAGAAAAATACTTAGCTTTTCTTTT
TCTTTTTTTGTGGAGGGGGGACGGAGAGGAACAAGGATGGGGAGGTAGGAATGAGGTATAGAAAAGAGATAGCATCTTCTTTGGCACAAG
ACTAGTGGCTTACCGCTTACCTTAGAGTTTTGTTTTTTTTTTTTCAAACCCATCAAAATCTACTTATTTATGAATCCAAGGGGTGGCAGC
ATCACTCTGTTCTAGCATTCTTTGTGGAGATGGTCTGGTGCCTAGCTGGGAGTGAGCAGCAGCCCATCCCCTGTTCACTTTCTCTAGCCC
ATCATTACCTGTGAACTGCAGTGGGGCAGTCATGGCAAATAGAATTGGGCTGGGGTTTCTCCTTCTTTTCAGTTCATTGTTTGCCCTGCT
AGGAATTAGAAGACAGACACCATGTCCCAGGACAGTGTTACTTCTTCTGCATGATGTGTGGTAGACTCCCTTTGCTGGCTTGTGCAGTGA
TACTGAGAAAATACATGAACAGAAACTGCCCAGGTGGAACAGCACGTAACCTAGTGAGTGACTGTACTCCTTTCTAGGAATGCTGATTCA
GAGTGCACCTCTTTGACTAGGTCCCAGGATCCCCTTGTCCCTGGAGTAGGGACTAACTATAGCACAAAGTAATATGTGCCAATGCTATTT
GTGAAATGTTTGGTCTTTCTAAACGACTAAAGGATTTGTTGGGTTTTTGCTTAAGTTTTGAACCAAATCCTAGAGCCAGCTGATAATATT
TAATAATCTGGAGGAGAGAATAATGATGTACCAATAAGTGGAGATTCCTCCTTATGATGTATGCTAGGTTATGGAAGATGTAAAATATTC
AACTTTTTCCTCCTTTTTTTGGACTTTGTATTTTACTGCATGTTTTCTTCATTTTTAATCAATAAAGAGTAAATTGTCCTTAACAAGTGT
GGCCACACAATGCGATCCAGAAGAGATCATCGTGCTCTCAGACTCTGATTAGCTGCCTCCCCTTCTCCCTGCCTCCAGAATGTTCTGGGA
TAACATTTGGAGGAAGGTGGGAAGCAGATGACTGAGGAAGGGATGGACTAAGCTAATCCCCTTTTGGTGGTGTTTCTTTAAAAAAAAAAA
AAAGCTTAAGTTTTACACAGAAACATTAATAAACAATAAAGTTCTTTTCTTACTGTATGCCCAGCCCACCTTCCCCCTTGGCTTCCTTGG
CCCCAGTTGCTGATTCCTCCACGAGGGTGGACTCTCCCAGCCATGGCCTGGTGACCAGCTCCCTCTGCATCCCTTCTCCAGCCCGGCTGT

>In-frame_ENST00000311806_ENST00000266000_BG114042_OXSR1_chr3_38294368_+_DAXX_chr6_33286940_length(amino acids)=627AA_start in transcript=201_stop in transcript=2084
MPRGDPAPRRRPTRGCSETIGGGAAAAAAAVGGGETRGEETSEVSEFEGGPRAAAAVMSEDSSALPWSINRDDYELQEVIGSGATAVVQA
AYCAPKKEKVAIKRINLEKCQTSMDELLKEIQAMSQCHHPNIVSYYTSFVVKDELWLVMKLLSGGSVLDIIKHIVAKGEHKSGVLDESTI
ATILREVLEGLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLATGGDITRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSF
GITAIELATGAAPYHKYPPMKVLMLTLQNDPPSLETGVQDKEMLKKYGKSFRKMISLCLQKDPEKRPTAAELLRHKFFQKAKNKEFLQEK
TLQRAPTISERAKKVRRVPGSSGRLHKTEDGGWEWSDDEFDEESEEGKAAISQLRSPRVKESISNSELFPTTDPVGTLLQVPEQISAHLP
QPAGQIATQPTQVSLPPTAEPAKTAQALSSGSGSQETKIPISLVLRLRNSKKELNDIRFEFTPGRDTAEGVSQELISAGLVDGRDLVIVA

--------------------------------------------------------------
>In-frame_ENST00000311806_ENST00000374542_BG114042_OXSR1_chr3_38294368_+_DAXX_chr6_33286940_length(transcript)=4904nt_BP=4492nt
GTGTCGGCAGGTGGAGGAAGAGGGGAAAGTTTGGCCCGTGCGTGGGGCTGGGGTGGAGGGCGGGACAGAGGGGCTGGGCCCAGGCAAAGC
TTCTGTCGCTGCTGCTGCGGAGGCCGAGGACAGGACGTGGGCTGGGCCGGGCAGTGCCGGACTCGGAGGAGCAGGAGGCGAGGTCCGCCG
GAGCTCTGAGCCCCCGCTGCTCTGCCGCGCGGTGACCCCGCGCCCCGGCGCCGTCCGACCCGTGGCTGTTCCGAGACGATTGGTGGGGGC
GCGGCGGCGGCGGCGGCGGCTGTTGGGGGTGGGGAGACGCGCGGCGAGGAGACGAGCGAGGTCAGCGAGTTTGAGGGAGGACCGCGAGCC
GCTGCCGCCGTCATGTCCGAGGACTCGAGCGCCCTGCCCTGGTCCATCAACAGGGACGATTACGAGCTGCAGGAGGTGATCGGGAGTGGA
GCAACTGCTGTAGTCCAAGCAGCTTATTGTGCCCCTAAAAAGGAGAAAGTGGCAATCAAACGGATAAACCTTGAGAAATGTCAAACTAGC
ATGGATGAACTCCTGAAAGAAATTCAAGCCATGAGTCAATGCCATCATCCTAATATTGTATCTTACTACACATCTTTTGTGGTAAAAGAT
GAGCTGTGGCTTGTCATGAAGCTGCTAAGTGGAGGTTCTGTTCTGGATATTATTAAGCACATTGTGGCAAAAGGGGAACACAAAAGTGGA
GTCCTAGATGAATCTACCATTGCTACGATACTCCGAGAAGTACTGGAAGGGCTGGAATATCTGCATAAAAATGGACAGATCCACAGAGAT
GTGAAAGCTGGAAACATTCTTCTTGGAGAAGATGGCTCAGTACAGATTGCAGACTTTGGGGTTAGTGCTTTTTTAGCAACTGGTGGTGAT
ATTACCCGAAATAAAGTGAGAAAGACCTTTGTTGGCACCCCTTGTTGGATGGCACCTGAAGTTATGGAACAGGTCCGTGGTTATGATTTC
AAAGCTGATATTTGGAGTTTTGGAATTACAGCAATTGAATTGGCTACAGGGGCGGCTCCTTATCATAAATATCCACCAATGAAGGTTTTA
ATGCTGACACTGCAGAACGATCCTCCTTCTTTGGAAACTGGTGTTCAAGATAAAGAAATGCTGAAAAAATATGGAAAATCATTTAGAAAA
ATGATTTCATTGTGCCTTCAAAAAGATCCAGAAAAAAGACCAACAGCAGCAGAACTATTAAGGCACAAATTTTTCCAGAAAGCAAAGAAT
AAAGAATTTCTTCAAGAAAAAACATTGCAGAGAGCACCAACCATTTCTGAAAGAGCAAAAAAGGTTCGGAGAGTACCAGGTTCCAGTGGG
CGTCTTCATAAGACAGAGGATGGAGGCTGGGAGTGGAGTGATGATGAATTTGATGAAGAAAGTGAGGAAGGGAAAGCAGCAATTTCACAA
CTCAGGTCTCCCCGAGTGAAAGAATCAATATCAAATTCTGAGCTCTTTCCAACAACTGATCCTGTGGGTACTTTGCTCCAAGTTCCAGAA
CAGATCTCTGCTCATCTACCTCAGCCAGCTGGGCAGATTGCTACACAGCCAACTCAAGTCTCTCTCCCACCCACCGCAGAGCCAGCAAAA
ACAGCTCAGGCTTTGTCTTCAGGATCAGGTTCACAAGAAACCAAGATCCCAATCAGTCTAGTACTAAGATTAAGGAATTCCAAAAAAGAA
CTAAATGATATTCGATTTGAATTTACTCCTGGGAGAGATACAGCAGAGGGTGTCTCTCAGGAACTCATTTCTGCTGGCCTGGTCGACGGA
AGGGATTTAGTAATAGTGGCAGCTAATTTGCAGAAAATTGTGGAAGAACCTCAGTCAAATCGATCTGTCACTTTCAAACTGTCAGCATCA
GCTAAACCACAACCCTGGAAGAGGCGGCCTAAGGAGATTCCACACATGCGTATCTCTGTTGCTTCTATTGGCCTAAACCCACTACTGCCA
AAGAACCCAGCAACAAACCTCCCGGCTAGGAGCTTTAGAAGTCTTTATGTTCTTCCTGCCATCATTCCTCCTTTTCCCACAGGGAAAGAA
AAGTTGGATCACTAGTGGCCAGCATCCCCAGAGTTCCGTTAGTAAACTTACTTCATATGTCCCCTGTCTTCCTCCATCTGAGAAGTGGCC
CATGTGCTTCAAGGCCCAGGAGGGAGATCTGTCAGCTCATTCTTGCCTTACTCCAATGATGGCCCAGGTGGAAAAGTAGCAGCTGTATCG
GGCTTCCTCATCCTGCCTGTTCCCCCACACCTGCCAGGATATGGACATCTTGGGATATCTCTTTACCACTGAAGTAGAATTGATTGTTCA
GCTGGAGCCCAGAGAATTTAATTTAATGTTTTTTCTTTGTACCTGATGTGAATTCTAGCAACCTTTGTTAGGAAAAAGCACAGCCTCAGA
TGGAGGCAGCCTAAACTGTGTTCTTGTTTTGTTCATGGTGTTTCTAAGCGTTTTGCTGAAGCTGCTCTCAGGCACCCCCTTCTTCATTGC
TCTCTCCAGAAAGGGTTGCTAGCCTTAACTTCAGCTGGTGCAAAACATCTGACTGTAGCCGAACTTCAGCCATCAGATCCTTCAAAGTGG
AACTTTGGATTGTTTTTACAGACAACATCGAGTAATGGCTTGTAAATGTGAATTTTGCCAGAGGTGGTTTTTGAACAGGAAAATCATAAT
TCATATCATTGGAGAAGTATTTATTTTCAAATATCAAATTGAAGAAAAACTCAATCCTCCCATGAAAATCAGTTCGCCTGGCCTCCAAGT
CGTGAGGAAATGGGTATGCAAGGCTGAGATTTCTACAGCAATAAAGGAGACACACACTGGGCCAGAGAGGCCTGCCTTCTGCCTGCTCTC
CTGCACTGACCCTTTGGAGGGGGTCTCTGTGTGCTGAAGCTAACTCAAGATGGAAAGTGAAACCACATGTGCCGTGACCTTTAGGTTTTA
TGAGTAGACAGTGTTCATTTGATTTTCTACAGAAATAATATAAATTATTCTTTAGGTTTAAAAAAGAGCACTCATAATGCAATATGTGAA
TAATCAGTGAGGTTGATTTTTCTTTTTTCCTACCGTTTCATAGTCTTTGTCTAACTGCTAGTAACCCTACCGAGTTTTATATATGAGTGG
GATACTCAATCTGGCCTTAAAAAGATACACAAAGATGGGCTGTGGGTCCCTGGAAAGGGGGAGAGTTGCCCTTTACAGAATCACTCGAGC
CCTTTCCAGCACTGTTGGTCTGATGAACAAGGTTGTTTTACCTTATTTTCTCTTGGAACATATCTGAAAACCTTCCCCACAAATAACTTG
TCACACCTTTTGTTTCATTCTGAGTCTTTAGTTTTAGTCATGGGCTTTCTTCACCTGCTCTAGGTGCAAAGGCATGTTGGGAAAGAGATG
GATGTTGGGGAGGAAGAGAGGAGATGGATTTCAGTTGGGAGTTAGGAGGAGAGTAGGTGAGATGATCAGACACCGGAGTTCAACGTCCCA
GCAGTCTTGGTAAAAGGAGGGAGCCTGCTGAGCCAGGAGGGAGAAAAGAAGATTGACCAGCTTGCTAGAAAAATACTTAGCTTTTCTTTT
TCTTTTTTTGTGGAGGGGGGACGGAGAGGAACAAGGATGGGGAGGTAGGAATGAGGTATAGAAAAGAGATAGCATCTTCTTTGGCACAAG
ACTAGTGGCTTACCGCTTACCTTAGAGTTTTGTTTTTTTTTTTTCAAACCCATCAAAATCTACTTATTTATGAATCCAAGGGGTGGCAGC
ATCACTCTGTTCTAGCATTCTTTGTGGAGATGGTCTGGTGCCTAGCTGGGAGTGAGCAGCAGCCCATCCCCTGTTCACTTTCTCTAGCCC
ATCATTACCTGTGAACTGCAGTGGGGCAGTCATGGCAAATAGAATTGGGCTGGGGTTTCTCCTTCTTTTCAGTTCATTGTTTGCCCTGCT
AGGAATTAGAAGACAGACACCATGTCCCAGGACAGTGTTACTTCTTCTGCATGATGTGTGGTAGACTCCCTTTGCTGGCTTGTGCAGTGA
TACTGAGAAAATACATGAACAGAAACTGCCCAGGTGGAACAGCACGTAACCTAGTGAGTGACTGTACTCCTTTCTAGGAATGCTGATTCA
GAGTGCACCTCTTTGACTAGGTCCCAGGATCCCCTTGTCCCTGGAGTAGGGACTAACTATAGCACAAAGTAATATGTGCCAATGCTATTT
GTGAAATGTTTGGTCTTTCTAAACGACTAAAGGATTTGTTGGGTTTTTGCTTAAGTTTTGAACCAAATCCTAGAGCCAGCTGATAATATT
TAATAATCTGGAGGAGAGAATAATGATGTACCAATAAGTGGAGATTCCTCCTTATGATGTATGCTAGGTTATGGAAGATGTAAAATATTC
AACTTTTTCCTCCTTTTTTTGGACTTTGTATTTTACTGCATGTTTTCTTCATTTTTAATCAATAAAGAGTAAATTGTCCTTAACAAGTGT
GGCCACACAATGCGATCCAGAAGAGATCATCGTGCTCTCAGACTCTGATTAGCTGCCTCCCCTTCTCCCTGCCTCCAGAATGTTCTGGGA
TAACATTTGGAGGAAGGTGGGAAGCAGATGACTGAGGAAGGGATGGACTAAGCTAATCCCCTTTTGGTGGTGTTTCTTTAAAAAAAAAAA
AAAGCTTAAGTTTTACACAGAAACATTAATAAACAATAAAGTTCTTTTCTTACTGTATGCCCAGCCCACCTTCCCCCTTGGCTTCCTTGG
CCCCAGTTGCTGATTCCTCCACGAGGGTGGACTCTCCCAGCCATGGCCTGGTGACCAGCTCCCTCTGCATCCCTTCTCCAGCCCGGCTGT

>In-frame_ENST00000311806_ENST00000374542_BG114042_OXSR1_chr3_38294368_+_DAXX_chr6_33286940_length(amino acids)=627AA_start in transcript=201_stop in transcript=2084
MPRGDPAPRRRPTRGCSETIGGGAAAAAAAVGGGETRGEETSEVSEFEGGPRAAAAVMSEDSSALPWSINRDDYELQEVIGSGATAVVQA
AYCAPKKEKVAIKRINLEKCQTSMDELLKEIQAMSQCHHPNIVSYYTSFVVKDELWLVMKLLSGGSVLDIIKHIVAKGEHKSGVLDESTI
ATILREVLEGLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLATGGDITRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSF
GITAIELATGAAPYHKYPPMKVLMLTLQNDPPSLETGVQDKEMLKKYGKSFRKMISLCLQKDPEKRPTAAELLRHKFFQKAKNKEFLQEK
TLQRAPTISERAKKVRRVPGSSGRLHKTEDGGWEWSDDEFDEESEEGKAAISQLRSPRVKESISNSELFPTTDPVGTLLQVPEQISAHLP
QPAGQIATQPTQVSLPPTAEPAKTAQALSSGSGSQETKIPISLVLRLRNSKKELNDIRFEFTPGRDTAEGVSQELISAGLVDGRDLVIVA

--------------------------------------------------------------
>In-frame_ENST00000311806_ENST00000414083_BG114042_OXSR1_chr3_38294368_+_DAXX_chr6_33286940_length(transcript)=4743nt_BP=4492nt
GTGTCGGCAGGTGGAGGAAGAGGGGAAAGTTTGGCCCGTGCGTGGGGCTGGGGTGGAGGGCGGGACAGAGGGGCTGGGCCCAGGCAAAGC
TTCTGTCGCTGCTGCTGCGGAGGCCGAGGACAGGACGTGGGCTGGGCCGGGCAGTGCCGGACTCGGAGGAGCAGGAGGCGAGGTCCGCCG
GAGCTCTGAGCCCCCGCTGCTCTGCCGCGCGGTGACCCCGCGCCCCGGCGCCGTCCGACCCGTGGCTGTTCCGAGACGATTGGTGGGGGC
GCGGCGGCGGCGGCGGCGGCTGTTGGGGGTGGGGAGACGCGCGGCGAGGAGACGAGCGAGGTCAGCGAGTTTGAGGGAGGACCGCGAGCC
GCTGCCGCCGTCATGTCCGAGGACTCGAGCGCCCTGCCCTGGTCCATCAACAGGGACGATTACGAGCTGCAGGAGGTGATCGGGAGTGGA
GCAACTGCTGTAGTCCAAGCAGCTTATTGTGCCCCTAAAAAGGAGAAAGTGGCAATCAAACGGATAAACCTTGAGAAATGTCAAACTAGC
ATGGATGAACTCCTGAAAGAAATTCAAGCCATGAGTCAATGCCATCATCCTAATATTGTATCTTACTACACATCTTTTGTGGTAAAAGAT
GAGCTGTGGCTTGTCATGAAGCTGCTAAGTGGAGGTTCTGTTCTGGATATTATTAAGCACATTGTGGCAAAAGGGGAACACAAAAGTGGA
GTCCTAGATGAATCTACCATTGCTACGATACTCCGAGAAGTACTGGAAGGGCTGGAATATCTGCATAAAAATGGACAGATCCACAGAGAT
GTGAAAGCTGGAAACATTCTTCTTGGAGAAGATGGCTCAGTACAGATTGCAGACTTTGGGGTTAGTGCTTTTTTAGCAACTGGTGGTGAT
ATTACCCGAAATAAAGTGAGAAAGACCTTTGTTGGCACCCCTTGTTGGATGGCACCTGAAGTTATGGAACAGGTCCGTGGTTATGATTTC
AAAGCTGATATTTGGAGTTTTGGAATTACAGCAATTGAATTGGCTACAGGGGCGGCTCCTTATCATAAATATCCACCAATGAAGGTTTTA
ATGCTGACACTGCAGAACGATCCTCCTTCTTTGGAAACTGGTGTTCAAGATAAAGAAATGCTGAAAAAATATGGAAAATCATTTAGAAAA
ATGATTTCATTGTGCCTTCAAAAAGATCCAGAAAAAAGACCAACAGCAGCAGAACTATTAAGGCACAAATTTTTCCAGAAAGCAAAGAAT
AAAGAATTTCTTCAAGAAAAAACATTGCAGAGAGCACCAACCATTTCTGAAAGAGCAAAAAAGGTTCGGAGAGTACCAGGTTCCAGTGGG
CGTCTTCATAAGACAGAGGATGGAGGCTGGGAGTGGAGTGATGATGAATTTGATGAAGAAAGTGAGGAAGGGAAAGCAGCAATTTCACAA
CTCAGGTCTCCCCGAGTGAAAGAATCAATATCAAATTCTGAGCTCTTTCCAACAACTGATCCTGTGGGTACTTTGCTCCAAGTTCCAGAA
CAGATCTCTGCTCATCTACCTCAGCCAGCTGGGCAGATTGCTACACAGCCAACTCAAGTCTCTCTCCCACCCACCGCAGAGCCAGCAAAA
ACAGCTCAGGCTTTGTCTTCAGGATCAGGTTCACAAGAAACCAAGATCCCAATCAGTCTAGTACTAAGATTAAGGAATTCCAAAAAAGAA
CTAAATGATATTCGATTTGAATTTACTCCTGGGAGAGATACAGCAGAGGGTGTCTCTCAGGAACTCATTTCTGCTGGCCTGGTCGACGGA
AGGGATTTAGTAATAGTGGCAGCTAATTTGCAGAAAATTGTGGAAGAACCTCAGTCAAATCGATCTGTCACTTTCAAACTGTCAGCATCA
GCTAAACCACAACCCTGGAAGAGGCGGCCTAAGGAGATTCCACACATGCGTATCTCTGTTGCTTCTATTGGCCTAAACCCACTACTGCCA
AAGAACCCAGCAACAAACCTCCCGGCTAGGAGCTTTAGAAGTCTTTATGTTCTTCCTGCCATCATTCCTCCTTTTCCCACAGGGAAAGAA
AAGTTGGATCACTAGTGGCCAGCATCCCCAGAGTTCCGTTAGTAAACTTACTTCATATGTCCCCTGTCTTCCTCCATCTGAGAAGTGGCC
CATGTGCTTCAAGGCCCAGGAGGGAGATCTGTCAGCTCATTCTTGCCTTACTCCAATGATGGCCCAGGTGGAAAAGTAGCAGCTGTATCG
GGCTTCCTCATCCTGCCTGTTCCCCCACACCTGCCAGGATATGGACATCTTGGGATATCTCTTTACCACTGAAGTAGAATTGATTGTTCA
GCTGGAGCCCAGAGAATTTAATTTAATGTTTTTTCTTTGTACCTGATGTGAATTCTAGCAACCTTTGTTAGGAAAAAGCACAGCCTCAGA
TGGAGGCAGCCTAAACTGTGTTCTTGTTTTGTTCATGGTGTTTCTAAGCGTTTTGCTGAAGCTGCTCTCAGGCACCCCCTTCTTCATTGC
TCTCTCCAGAAAGGGTTGCTAGCCTTAACTTCAGCTGGTGCAAAACATCTGACTGTAGCCGAACTTCAGCCATCAGATCCTTCAAAGTGG
AACTTTGGATTGTTTTTACAGACAACATCGAGTAATGGCTTGTAAATGTGAATTTTGCCAGAGGTGGTTTTTGAACAGGAAAATCATAAT
TCATATCATTGGAGAAGTATTTATTTTCAAATATCAAATTGAAGAAAAACTCAATCCTCCCATGAAAATCAGTTCGCCTGGCCTCCAAGT
CGTGAGGAAATGGGTATGCAAGGCTGAGATTTCTACAGCAATAAAGGAGACACACACTGGGCCAGAGAGGCCTGCCTTCTGCCTGCTCTC
CTGCACTGACCCTTTGGAGGGGGTCTCTGTGTGCTGAAGCTAACTCAAGATGGAAAGTGAAACCACATGTGCCGTGACCTTTAGGTTTTA
TGAGTAGACAGTGTTCATTTGATTTTCTACAGAAATAATATAAATTATTCTTTAGGTTTAAAAAAGAGCACTCATAATGCAATATGTGAA
TAATCAGTGAGGTTGATTTTTCTTTTTTCCTACCGTTTCATAGTCTTTGTCTAACTGCTAGTAACCCTACCGAGTTTTATATATGAGTGG
GATACTCAATCTGGCCTTAAAAAGATACACAAAGATGGGCTGTGGGTCCCTGGAAAGGGGGAGAGTTGCCCTTTACAGAATCACTCGAGC
CCTTTCCAGCACTGTTGGTCTGATGAACAAGGTTGTTTTACCTTATTTTCTCTTGGAACATATCTGAAAACCTTCCCCACAAATAACTTG
TCACACCTTTTGTTTCATTCTGAGTCTTTAGTTTTAGTCATGGGCTTTCTTCACCTGCTCTAGGTGCAAAGGCATGTTGGGAAAGAGATG
GATGTTGGGGAGGAAGAGAGGAGATGGATTTCAGTTGGGAGTTAGGAGGAGAGTAGGTGAGATGATCAGACACCGGAGTTCAACGTCCCA
GCAGTCTTGGTAAAAGGAGGGAGCCTGCTGAGCCAGGAGGGAGAAAAGAAGATTGACCAGCTTGCTAGAAAAATACTTAGCTTTTCTTTT
TCTTTTTTTGTGGAGGGGGGACGGAGAGGAACAAGGATGGGGAGGTAGGAATGAGGTATAGAAAAGAGATAGCATCTTCTTTGGCACAAG
ACTAGTGGCTTACCGCTTACCTTAGAGTTTTGTTTTTTTTTTTTCAAACCCATCAAAATCTACTTATTTATGAATCCAAGGGGTGGCAGC
ATCACTCTGTTCTAGCATTCTTTGTGGAGATGGTCTGGTGCCTAGCTGGGAGTGAGCAGCAGCCCATCCCCTGTTCACTTTCTCTAGCCC
ATCATTACCTGTGAACTGCAGTGGGGCAGTCATGGCAAATAGAATTGGGCTGGGGTTTCTCCTTCTTTTCAGTTCATTGTTTGCCCTGCT
AGGAATTAGAAGACAGACACCATGTCCCAGGACAGTGTTACTTCTTCTGCATGATGTGTGGTAGACTCCCTTTGCTGGCTTGTGCAGTGA
TACTGAGAAAATACATGAACAGAAACTGCCCAGGTGGAACAGCACGTAACCTAGTGAGTGACTGTACTCCTTTCTAGGAATGCTGATTCA
GAGTGCACCTCTTTGACTAGGTCCCAGGATCCCCTTGTCCCTGGAGTAGGGACTAACTATAGCACAAAGTAATATGTGCCAATGCTATTT
GTGAAATGTTTGGTCTTTCTAAACGACTAAAGGATTTGTTGGGTTTTTGCTTAAGTTTTGAACCAAATCCTAGAGCCAGCTGATAATATT
TAATAATCTGGAGGAGAGAATAATGATGTACCAATAAGTGGAGATTCCTCCTTATGATGTATGCTAGGTTATGGAAGATGTAAAATATTC
AACTTTTTCCTCCTTTTTTTGGACTTTGTATTTTACTGCATGTTTTCTTCATTTTTAATCAATAAAGAGTAAATTGTCCTTAACAAGTGT
GGCCACACAATGCGATCCAGAAGAGATCATCGTGCTCTCAGACTCTGATTAGCTGCCTCCCCTTCTCCCTGCCTCCTGCCCAGCCCACCT
TCCCCCTTGGCTTCCTTGGCCCCAGTTGCTGATTCCTCCACGAGGGTGGACTCTCCCAGCCATGGCCTGGTGACCAGCTCCCTCTGCATC

>In-frame_ENST00000311806_ENST00000414083_BG114042_OXSR1_chr3_38294368_+_DAXX_chr6_33286940_length(amino acids)=627AA_start in transcript=201_stop in transcript=2084
MPRGDPAPRRRPTRGCSETIGGGAAAAAAAVGGGETRGEETSEVSEFEGGPRAAAAVMSEDSSALPWSINRDDYELQEVIGSGATAVVQA
AYCAPKKEKVAIKRINLEKCQTSMDELLKEIQAMSQCHHPNIVSYYTSFVVKDELWLVMKLLSGGSVLDIIKHIVAKGEHKSGVLDESTI
ATILREVLEGLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLATGGDITRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSF
GITAIELATGAAPYHKYPPMKVLMLTLQNDPPSLETGVQDKEMLKKYGKSFRKMISLCLQKDPEKRPTAAELLRHKFFQKAKNKEFLQEK
TLQRAPTISERAKKVRRVPGSSGRLHKTEDGGWEWSDDEFDEESEEGKAAISQLRSPRVKESISNSELFPTTDPVGTLLQVPEQISAHLP
QPAGQIATQPTQVSLPPTAEPAKTAQALSSGSGSQETKIPISLVLRLRNSKKELNDIRFEFTPGRDTAEGVSQELISAGLVDGRDLVIVA

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Fusion Gene PPI Analysis for OXSR1-DAXX


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneDAXXchr3:38294368chr6:33286940ENST0000026600008183_4170741.0histone H3.3
TgeneDAXXchr3:38294368chr6:33286940ENST0000037454208183_4170741.0histone H3.3
TgeneDAXXchr3:38294368chr6:33286940ENST0000038306208183_4170741.0histone H3.3
TgeneDAXXchr3:38294368chr6:33286940ENST0000038319408183_4170741.0histone H3.3
TgeneDAXXchr3:38294368chr6:33286940ENST0000039906008183_4170741.0histone H3.3
TgeneDAXXchr3:38294368chr6:33286940ENST0000039934408183_4170741.0histone H3.3
TgeneDAXXchr3:38294368chr6:33286940ENST0000041408307183_4170666.0histone H3.3
TgeneDAXXchr3:38294368chr6:33286940ENST0000043348208183_4170741.0histone H3.3
TgeneDAXXchr3:38294368chr6:33286940ENST0000043631108183_4170741.0histone H3.3
TgeneDAXXchr3:38294368chr6:33286940ENST0000044500908183_4170741.0histone H3.3
TgeneDAXXchr3:38294368chr6:33286940ENST0000045586008183_4170741.0histone H3.3
TgeneDAXXchr3:38294368chr6:33286940ENST0000026600008501_6250741.0MAP3K5
TgeneDAXXchr3:38294368chr6:33286940ENST0000037454208501_6250741.0MAP3K5
TgeneDAXXchr3:38294368chr6:33286940ENST0000038306208501_6250741.0MAP3K5
TgeneDAXXchr3:38294368chr6:33286940ENST0000038319408501_6250741.0MAP3K5
TgeneDAXXchr3:38294368chr6:33286940ENST0000039906008501_6250741.0MAP3K5
TgeneDAXXchr3:38294368chr6:33286940ENST0000039934408501_6250741.0MAP3K5
TgeneDAXXchr3:38294368chr6:33286940ENST0000041408307501_6250666.0MAP3K5
TgeneDAXXchr3:38294368chr6:33286940ENST0000043348208501_6250741.0MAP3K5
TgeneDAXXchr3:38294368chr6:33286940ENST0000043631108501_6250741.0MAP3K5
TgeneDAXXchr3:38294368chr6:33286940ENST0000044500908501_6250741.0MAP3K5
TgeneDAXXchr3:38294368chr6:33286940ENST0000045586008501_6250741.0MAP3K5
TgeneDAXXchr3:38294368chr6:33286940ENST0000026600008626_7400741.0SPOP
TgeneDAXXchr3:38294368chr6:33286940ENST0000037454208626_7400741.0SPOP
TgeneDAXXchr3:38294368chr6:33286940ENST0000038306208626_7400741.0SPOP
TgeneDAXXchr3:38294368chr6:33286940ENST0000038319408626_7400741.0SPOP
TgeneDAXXchr3:38294368chr6:33286940ENST0000039906008626_7400741.0SPOP
TgeneDAXXchr3:38294368chr6:33286940ENST0000039934408626_7400741.0SPOP
TgeneDAXXchr3:38294368chr6:33286940ENST0000041408307626_7400666.0SPOP
TgeneDAXXchr3:38294368chr6:33286940ENST0000043348208626_7400741.0SPOP
TgeneDAXXchr3:38294368chr6:33286940ENST0000043631108626_7400741.0SPOP
TgeneDAXXchr3:38294368chr6:33286940ENST0000044500908626_7400741.0SPOP
TgeneDAXXchr3:38294368chr6:33286940ENST0000045586008626_7400741.0SPOP


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for OXSR1-DAXX


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for OXSR1-DAXX


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneOXSR1C0020538Hypertensive disease1CTD_human
HgeneOXSR1C0036341Schizophrenia1PSYGENET
TgeneDAXXC0030297Pancreatic Neoplasm1CTD_human
TgeneDAXXC0206686Adrenocortical carcinoma1CTD_human
TgeneDAXXC0206754Neuroendocrine Tumors1CTD_human
TgeneDAXXC0346647Malignant neoplasm of pancreas1CTD_human