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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:PAM-PAM (FusionGDB2 ID:62110)

Fusion Gene Summary for PAM-PAM

check button Fusion gene summary
Fusion gene informationFusion gene name: PAM-PAM
Fusion gene ID: 62110
HgeneTgene
Gene symbol

PAM

PAM

Gene ID

23077

23077

Gene nameMYC binding protein 2MYC binding protein 2
SynonymsMyc-bp2|PAM|PHR1|PhrMyc-bp2|PAM|PHR1|Phr
Cytomap

13q22.3

13q22.3

Type of geneprotein-codingprotein-coding
DescriptionE3 ubiquitin-protein ligase MYCBP2HighwireMYC binding protein 2, E3 ubiquitin protein ligasePAM/Highwire/RPM-1 protein 1RING-type E3 ubiquitin transferase MYCBP2myc-binding protein 2pam/highwire/rpm-1 proteinprotein associated with MycE3 ubiquitin-protein ligase MYCBP2HighwireMYC binding protein 2, E3 ubiquitin protein ligasePAM/Highwire/RPM-1 protein 1RING-type E3 ubiquitin transferase MYCBP2myc-binding protein 2pam/highwire/rpm-1 proteinprotein associated with Myc
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000438793, ENST00000346918, 
ENST00000379787, ENST00000348126, 
ENST00000304400, ENST00000274392, 
ENST00000455264, ENST00000513648, 
ENST00000438793, ENST00000346918, 
ENST00000379787, ENST00000348126, 
ENST00000304400, ENST00000274392, 
ENST00000455264, ENST00000513648, 
Fusion gene scores* DoF score2 X 3 X 1=610 X 12 X 3=360
# samples 310
** MAII scorelog2(3/6*10)=2.32192809488736log2(10/360*10)=-1.84799690655495
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: PAM [Title/Abstract] AND PAM [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointPAM(102345529)-PAM(102353088), # samples:1
PAM(102363943)-PAM(102364762), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgenePAM

GO:0016567

protein ubiquitination

29643511

HgenePAM

GO:0031398

positive regulation of protein ubiquitination

20534529

TgenePAM

GO:0016567

protein ubiquitination

29643511

TgenePAM

GO:0031398

positive regulation of protein ubiquitination

20534529


check buttonFusion gene breakpoints across PAM (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across PAM (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChiTaRS5.0N/ABM699806PAMchr5

102345529

-PAMchr5

102353088

+
ChiTaRS5.0N/AN68233PAMchr5

102363943

+PAMchr5

102364762

-


Top

Fusion Gene ORF analysis for PAM-PAM

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000438793ENST00000438793PAMchr5

102345529

-PAMchr5

102353088

+
In-frameENST00000438793ENST00000346918PAMchr5

102345529

-PAMchr5

102353088

+
In-frameENST00000438793ENST00000379787PAMchr5

102345529

-PAMchr5

102353088

+
In-frameENST00000438793ENST00000348126PAMchr5

102345529

-PAMchr5

102353088

+
In-frameENST00000438793ENST00000304400PAMchr5

102345529

-PAMchr5

102353088

+
In-frameENST00000438793ENST00000274392PAMchr5

102345529

-PAMchr5

102353088

+
In-frameENST00000438793ENST00000455264PAMchr5

102345529

-PAMchr5

102353088

+
5CDS-intronENST00000438793ENST00000513648PAMchr5

102345529

-PAMchr5

102353088

+
In-frameENST00000346918ENST00000438793PAMchr5

102345529

-PAMchr5

102353088

+
In-frameENST00000346918ENST00000346918PAMchr5

102345529

-PAMchr5

102353088

+
In-frameENST00000346918ENST00000379787PAMchr5

102345529

-PAMchr5

102353088

+
In-frameENST00000346918ENST00000348126PAMchr5

102345529

-PAMchr5

102353088

+
In-frameENST00000346918ENST00000304400PAMchr5

102345529

-PAMchr5

102353088

+
In-frameENST00000346918ENST00000274392PAMchr5

102345529

-PAMchr5

102353088

+
In-frameENST00000346918ENST00000455264PAMchr5

102345529

-PAMchr5

102353088

+
5CDS-intronENST00000346918ENST00000513648PAMchr5

102345529

-PAMchr5

102353088

+
In-frameENST00000379787ENST00000438793PAMchr5

102345529

-PAMchr5

102353088

+
In-frameENST00000379787ENST00000346918PAMchr5

102345529

-PAMchr5

102353088

+
In-frameENST00000379787ENST00000379787PAMchr5

102345529

-PAMchr5

102353088

+
In-frameENST00000379787ENST00000348126PAMchr5

102345529

-PAMchr5

102353088

+
In-frameENST00000379787ENST00000304400PAMchr5

102345529

-PAMchr5

102353088

+
In-frameENST00000379787ENST00000274392PAMchr5

102345529

-PAMchr5

102353088

+
In-frameENST00000379787ENST00000455264PAMchr5

102345529

-PAMchr5

102353088

+
5CDS-intronENST00000379787ENST00000513648PAMchr5

102345529

-PAMchr5

102353088

+
In-frameENST00000348126ENST00000438793PAMchr5

102345529

-PAMchr5

102353088

+
In-frameENST00000348126ENST00000346918PAMchr5

102345529

-PAMchr5

102353088

+
In-frameENST00000348126ENST00000379787PAMchr5

102345529

-PAMchr5

102353088

+
In-frameENST00000348126ENST00000348126PAMchr5

102345529

-PAMchr5

102353088

+
In-frameENST00000348126ENST00000304400PAMchr5

102345529

-PAMchr5

102353088

+
In-frameENST00000348126ENST00000274392PAMchr5

102345529

-PAMchr5

102353088

+
In-frameENST00000348126ENST00000455264PAMchr5

102345529

-PAMchr5

102353088

+
5CDS-intronENST00000348126ENST00000513648PAMchr5

102345529

-PAMchr5

102353088

+
In-frameENST00000304400ENST00000438793PAMchr5

102345529

-PAMchr5

102353088

+
In-frameENST00000304400ENST00000346918PAMchr5

102345529

-PAMchr5

102353088

+
In-frameENST00000304400ENST00000379787PAMchr5

102345529

-PAMchr5

102353088

+
In-frameENST00000304400ENST00000348126PAMchr5

102345529

-PAMchr5

102353088

+
In-frameENST00000304400ENST00000304400PAMchr5

102345529

-PAMchr5

102353088

+
In-frameENST00000304400ENST00000274392PAMchr5

102345529

-PAMchr5

102353088

+
In-frameENST00000304400ENST00000455264PAMchr5

102345529

-PAMchr5

102353088

+
5CDS-intronENST00000304400ENST00000513648PAMchr5

102345529

-PAMchr5

102353088

+
In-frameENST00000274392ENST00000438793PAMchr5

102345529

-PAMchr5

102353088

+
In-frameENST00000274392ENST00000346918PAMchr5

102345529

-PAMchr5

102353088

+
In-frameENST00000274392ENST00000379787PAMchr5

102345529

-PAMchr5

102353088

+
In-frameENST00000274392ENST00000348126PAMchr5

102345529

-PAMchr5

102353088

+
In-frameENST00000274392ENST00000304400PAMchr5

102345529

-PAMchr5

102353088

+
In-frameENST00000274392ENST00000274392PAMchr5

102345529

-PAMchr5

102353088

+
In-frameENST00000274392ENST00000455264PAMchr5

102345529

-PAMchr5

102353088

+
5CDS-intronENST00000274392ENST00000513648PAMchr5

102345529

-PAMchr5

102353088

+
In-frameENST00000455264ENST00000438793PAMchr5

102345529

-PAMchr5

102353088

+
In-frameENST00000455264ENST00000346918PAMchr5

102345529

-PAMchr5

102353088

+
In-frameENST00000455264ENST00000379787PAMchr5

102345529

-PAMchr5

102353088

+
In-frameENST00000455264ENST00000348126PAMchr5

102345529

-PAMchr5

102353088

+
In-frameENST00000455264ENST00000304400PAMchr5

102345529

-PAMchr5

102353088

+
In-frameENST00000455264ENST00000274392PAMchr5

102345529

-PAMchr5

102353088

+
In-frameENST00000455264ENST00000455264PAMchr5

102345529

-PAMchr5

102353088

+
5CDS-intronENST00000455264ENST00000513648PAMchr5

102345529

-PAMchr5

102353088

+
intron-3CDSENST00000513648ENST00000438793PAMchr5

102345529

-PAMchr5

102353088

+
intron-3CDSENST00000513648ENST00000346918PAMchr5

102345529

-PAMchr5

102353088

+
intron-3CDSENST00000513648ENST00000379787PAMchr5

102345529

-PAMchr5

102353088

+
intron-3CDSENST00000513648ENST00000348126PAMchr5

102345529

-PAMchr5

102353088

+
intron-3CDSENST00000513648ENST00000304400PAMchr5

102345529

-PAMchr5

102353088

+
intron-3CDSENST00000513648ENST00000274392PAMchr5

102345529

-PAMchr5

102353088

+
intron-3CDSENST00000513648ENST00000455264PAMchr5

102345529

-PAMchr5

102353088

+
intron-intronENST00000513648ENST00000513648PAMchr5

102345529

-PAMchr5

102353088

+
Frame-shiftENST00000438793ENST00000438793PAMchr5

102363943

+PAMchr5

102364762

-
In-frameENST00000438793ENST00000346918PAMchr5

102363943

+PAMchr5

102364762

-
Frame-shiftENST00000438793ENST00000379787PAMchr5

102363943

+PAMchr5

102364762

-
Frame-shiftENST00000438793ENST00000348126PAMchr5

102363943

+PAMchr5

102364762

-
Frame-shiftENST00000438793ENST00000304400PAMchr5

102363943

+PAMchr5

102364762

-
In-frameENST00000438793ENST00000274392PAMchr5

102363943

+PAMchr5

102364762

-
Frame-shiftENST00000438793ENST00000455264PAMchr5

102363943

+PAMchr5

102364762

-
5CDS-intronENST00000438793ENST00000513648PAMchr5

102363943

+PAMchr5

102364762

-
intron-3CDSENST00000346918ENST00000438793PAMchr5

102363943

+PAMchr5

102364762

-
intron-3CDSENST00000346918ENST00000346918PAMchr5

102363943

+PAMchr5

102364762

-
intron-3CDSENST00000346918ENST00000379787PAMchr5

102363943

+PAMchr5

102364762

-
intron-3CDSENST00000346918ENST00000348126PAMchr5

102363943

+PAMchr5

102364762

-
intron-3CDSENST00000346918ENST00000304400PAMchr5

102363943

+PAMchr5

102364762

-
intron-3CDSENST00000346918ENST00000274392PAMchr5

102363943

+PAMchr5

102364762

-
intron-3CDSENST00000346918ENST00000455264PAMchr5

102363943

+PAMchr5

102364762

-
intron-intronENST00000346918ENST00000513648PAMchr5

102363943

+PAMchr5

102364762

-
intron-3CDSENST00000379787ENST00000438793PAMchr5

102363943

+PAMchr5

102364762

-
intron-3CDSENST00000379787ENST00000346918PAMchr5

102363943

+PAMchr5

102364762

-
intron-3CDSENST00000379787ENST00000379787PAMchr5

102363943

+PAMchr5

102364762

-
intron-3CDSENST00000379787ENST00000348126PAMchr5

102363943

+PAMchr5

102364762

-
intron-3CDSENST00000379787ENST00000304400PAMchr5

102363943

+PAMchr5

102364762

-
intron-3CDSENST00000379787ENST00000274392PAMchr5

102363943

+PAMchr5

102364762

-
intron-3CDSENST00000379787ENST00000455264PAMchr5

102363943

+PAMchr5

102364762

-
intron-intronENST00000379787ENST00000513648PAMchr5

102363943

+PAMchr5

102364762

-
Frame-shiftENST00000348126ENST00000438793PAMchr5

102363943

+PAMchr5

102364762

-
In-frameENST00000348126ENST00000346918PAMchr5

102363943

+PAMchr5

102364762

-
Frame-shiftENST00000348126ENST00000379787PAMchr5

102363943

+PAMchr5

102364762

-
Frame-shiftENST00000348126ENST00000348126PAMchr5

102363943

+PAMchr5

102364762

-
Frame-shiftENST00000348126ENST00000304400PAMchr5

102363943

+PAMchr5

102364762

-
In-frameENST00000348126ENST00000274392PAMchr5

102363943

+PAMchr5

102364762

-
Frame-shiftENST00000348126ENST00000455264PAMchr5

102363943

+PAMchr5

102364762

-
5CDS-intronENST00000348126ENST00000513648PAMchr5

102363943

+PAMchr5

102364762

-
Frame-shiftENST00000304400ENST00000438793PAMchr5

102363943

+PAMchr5

102364762

-
In-frameENST00000304400ENST00000346918PAMchr5

102363943

+PAMchr5

102364762

-
Frame-shiftENST00000304400ENST00000379787PAMchr5

102363943

+PAMchr5

102364762

-
Frame-shiftENST00000304400ENST00000348126PAMchr5

102363943

+PAMchr5

102364762

-
Frame-shiftENST00000304400ENST00000304400PAMchr5

102363943

+PAMchr5

102364762

-
In-frameENST00000304400ENST00000274392PAMchr5

102363943

+PAMchr5

102364762

-
Frame-shiftENST00000304400ENST00000455264PAMchr5

102363943

+PAMchr5

102364762

-
5CDS-intronENST00000304400ENST00000513648PAMchr5

102363943

+PAMchr5

102364762

-
Frame-shiftENST00000274392ENST00000438793PAMchr5

102363943

+PAMchr5

102364762

-
In-frameENST00000274392ENST00000346918PAMchr5

102363943

+PAMchr5

102364762

-
Frame-shiftENST00000274392ENST00000379787PAMchr5

102363943

+PAMchr5

102364762

-
Frame-shiftENST00000274392ENST00000348126PAMchr5

102363943

+PAMchr5

102364762

-
Frame-shiftENST00000274392ENST00000304400PAMchr5

102363943

+PAMchr5

102364762

-
In-frameENST00000274392ENST00000274392PAMchr5

102363943

+PAMchr5

102364762

-
Frame-shiftENST00000274392ENST00000455264PAMchr5

102363943

+PAMchr5

102364762

-
5CDS-intronENST00000274392ENST00000513648PAMchr5

102363943

+PAMchr5

102364762

-
Frame-shiftENST00000455264ENST00000438793PAMchr5

102363943

+PAMchr5

102364762

-
In-frameENST00000455264ENST00000346918PAMchr5

102363943

+PAMchr5

102364762

-
Frame-shiftENST00000455264ENST00000379787PAMchr5

102363943

+PAMchr5

102364762

-
Frame-shiftENST00000455264ENST00000348126PAMchr5

102363943

+PAMchr5

102364762

-
Frame-shiftENST00000455264ENST00000304400PAMchr5

102363943

+PAMchr5

102364762

-
In-frameENST00000455264ENST00000274392PAMchr5

102363943

+PAMchr5

102364762

-
Frame-shiftENST00000455264ENST00000455264PAMchr5

102363943

+PAMchr5

102364762

-
5CDS-intronENST00000455264ENST00000513648PAMchr5

102363943

+PAMchr5

102364762

-
intron-3CDSENST00000513648ENST00000438793PAMchr5

102363943

+PAMchr5

102364762

-
intron-3CDSENST00000513648ENST00000346918PAMchr5

102363943

+PAMchr5

102364762

-
intron-3CDSENST00000513648ENST00000379787PAMchr5

102363943

+PAMchr5

102364762

-
intron-3CDSENST00000513648ENST00000348126PAMchr5

102363943

+PAMchr5

102364762

-
intron-3CDSENST00000513648ENST00000304400PAMchr5

102363943

+PAMchr5

102364762

-
intron-3CDSENST00000513648ENST00000274392PAMchr5

102363943

+PAMchr5

102364762

-
intron-3CDSENST00000513648ENST00000455264PAMchr5

102363943

+PAMchr5

102364762

-
intron-intronENST00000513648ENST00000513648PAMchr5

102363943

+PAMchr5

102364762

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score

Top

Fusion Genomic Features for PAM-PAM


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

Top

Fusion Protein Features for PAM-PAM


check button Go to

FGviewer for the breakpoints of chr5:102345529-chr5:102353088

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePAMchr5:102363943chr5:102364762ENST00000304400+24251_494915.3333333333334975.0RegionPeptidylglycine alpha-hydroxylating monooxygenase
HgenePAMchr5:102363943chr5:102364762ENST00000304400+2425495_817915.3333333333334975.0RegionPeptidyl-alpha-hydroxyglycine alpha-amidating lyase
HgenePAMchr5:102363943chr5:102364762ENST00000348126+23241_494807.3333333333334867.0RegionPeptidylglycine alpha-hydroxylating monooxygenase
HgenePAMchr5:102363943chr5:102364762ENST00000438793+24251_494914.3333333333334974.0RegionPeptidylglycine alpha-hydroxylating monooxygenase
HgenePAMchr5:102363943chr5:102364762ENST00000438793+2425495_817914.3333333333334974.0RegionPeptidyl-alpha-hydroxyglycine alpha-amidating lyase
HgenePAMchr5:102363943chr5:102364762ENST00000455264+23241_494846.3333333333334906.0RegionPeptidylglycine alpha-hydroxylating monooxygenase
HgenePAMchr5:102363943chr5:102364762ENST00000455264+2324495_817846.3333333333334906.0RegionPeptidyl-alpha-hydroxyglycine alpha-amidating lyase
HgenePAMchr5:102363943chr5:102364762ENST00000304400+2425498_541915.3333333333334975.0RepeatNote=NHL 1
HgenePAMchr5:102363943chr5:102364762ENST00000304400+2425567_608915.3333333333334975.0RepeatNote=NHL 2
HgenePAMchr5:102363943chr5:102364762ENST00000304400+2425617_662915.3333333333334975.0RepeatNote=NHL 3
HgenePAMchr5:102363943chr5:102364762ENST00000304400+2425670_714915.3333333333334975.0RepeatNote=NHL 4
HgenePAMchr5:102363943chr5:102364762ENST00000304400+2425766_809915.3333333333334975.0RepeatNote=NHL 5
HgenePAMchr5:102363943chr5:102364762ENST00000348126+2324498_541807.3333333333334867.0RepeatNote=NHL 1
HgenePAMchr5:102363943chr5:102364762ENST00000348126+2324567_608807.3333333333334867.0RepeatNote=NHL 2
HgenePAMchr5:102363943chr5:102364762ENST00000348126+2324617_662807.3333333333334867.0RepeatNote=NHL 3
HgenePAMchr5:102363943chr5:102364762ENST00000348126+2324670_714807.3333333333334867.0RepeatNote=NHL 4
HgenePAMchr5:102363943chr5:102364762ENST00000348126+2324766_809807.3333333333334867.0RepeatNote=NHL 5
HgenePAMchr5:102363943chr5:102364762ENST00000438793+2425498_541914.3333333333334974.0RepeatNote=NHL 1
HgenePAMchr5:102363943chr5:102364762ENST00000438793+2425567_608914.3333333333334974.0RepeatNote=NHL 2
HgenePAMchr5:102363943chr5:102364762ENST00000438793+2425617_662914.3333333333334974.0RepeatNote=NHL 3
HgenePAMchr5:102363943chr5:102364762ENST00000438793+2425670_714914.3333333333334974.0RepeatNote=NHL 4
HgenePAMchr5:102363943chr5:102364762ENST00000438793+2425766_809914.3333333333334974.0RepeatNote=NHL 5
HgenePAMchr5:102363943chr5:102364762ENST00000455264+2324498_541846.3333333333334906.0RepeatNote=NHL 1
HgenePAMchr5:102363943chr5:102364762ENST00000455264+2324567_608846.3333333333334906.0RepeatNote=NHL 2
HgenePAMchr5:102363943chr5:102364762ENST00000455264+2324617_662846.3333333333334906.0RepeatNote=NHL 3
HgenePAMchr5:102363943chr5:102364762ENST00000455264+2324670_714846.3333333333334906.0RepeatNote=NHL 4
HgenePAMchr5:102363943chr5:102364762ENST00000455264+2324766_809846.3333333333334906.0RepeatNote=NHL 5
HgenePAMchr5:102363943chr5:102364762ENST00000304400+242531_863915.3333333333334975.0Topological domainIntragranular
HgenePAMchr5:102363943chr5:102364762ENST00000438793+242531_863914.3333333333334974.0Topological domainIntragranular
HgenePAMchr5:102363943chr5:102364762ENST00000304400+2425864_887915.3333333333334975.0TransmembraneHelical
HgenePAMchr5:102363943chr5:102364762ENST00000438793+2425864_887914.3333333333334974.0TransmembraneHelical
TgenePAMchr5:102345529chr5:102353088ENST000003044000251_4940975.0RegionPeptidylglycine alpha-hydroxylating monooxygenase
TgenePAMchr5:102345529chr5:102353088ENST00000304400025495_8170975.0RegionPeptidyl-alpha-hydroxyglycine alpha-amidating lyase
TgenePAMchr5:102345529chr5:102353088ENST000003469180231_4940888.0RegionPeptidylglycine alpha-hydroxylating monooxygenase
TgenePAMchr5:102345529chr5:102353088ENST00000346918023495_8170888.0RegionPeptidyl-alpha-hydroxyglycine alpha-amidating lyase
TgenePAMchr5:102345529chr5:102353088ENST000003481260241_4940867.0RegionPeptidylglycine alpha-hydroxylating monooxygenase
TgenePAMchr5:102345529chr5:102353088ENST00000348126024495_8170867.0RegionPeptidyl-alpha-hydroxyglycine alpha-amidating lyase
TgenePAMchr5:102345529chr5:102353088ENST000004387930251_4940974.0RegionPeptidylglycine alpha-hydroxylating monooxygenase
TgenePAMchr5:102345529chr5:102353088ENST00000438793025495_8170974.0RegionPeptidyl-alpha-hydroxyglycine alpha-amidating lyase
TgenePAMchr5:102345529chr5:102353088ENST000004552640241_4940906.0RegionPeptidylglycine alpha-hydroxylating monooxygenase
TgenePAMchr5:102345529chr5:102353088ENST00000455264024495_8170906.0RegionPeptidyl-alpha-hydroxyglycine alpha-amidating lyase
TgenePAMchr5:102363943chr5:102364762ENST000003044000251_4940975.0RegionPeptidylglycine alpha-hydroxylating monooxygenase
TgenePAMchr5:102363943chr5:102364762ENST00000304400025495_8170975.0RegionPeptidyl-alpha-hydroxyglycine alpha-amidating lyase
TgenePAMchr5:102363943chr5:102364762ENST000003469180231_4940888.0RegionPeptidylglycine alpha-hydroxylating monooxygenase
TgenePAMchr5:102363943chr5:102364762ENST00000346918023495_8170888.0RegionPeptidyl-alpha-hydroxyglycine alpha-amidating lyase
TgenePAMchr5:102363943chr5:102364762ENST000003481260241_4940867.0RegionPeptidylglycine alpha-hydroxylating monooxygenase
TgenePAMchr5:102363943chr5:102364762ENST00000348126024495_8170867.0RegionPeptidyl-alpha-hydroxyglycine alpha-amidating lyase
TgenePAMchr5:102363943chr5:102364762ENST000004387930251_4940974.0RegionPeptidylglycine alpha-hydroxylating monooxygenase
TgenePAMchr5:102363943chr5:102364762ENST00000438793025495_8170974.0RegionPeptidyl-alpha-hydroxyglycine alpha-amidating lyase
TgenePAMchr5:102363943chr5:102364762ENST000004552640241_4940906.0RegionPeptidylglycine alpha-hydroxylating monooxygenase
TgenePAMchr5:102363943chr5:102364762ENST00000455264024495_8170906.0RegionPeptidyl-alpha-hydroxyglycine alpha-amidating lyase
TgenePAMchr5:102345529chr5:102353088ENST00000304400025498_5410975.0RepeatNote=NHL 1
TgenePAMchr5:102345529chr5:102353088ENST00000304400025567_6080975.0RepeatNote=NHL 2
TgenePAMchr5:102345529chr5:102353088ENST00000304400025617_6620975.0RepeatNote=NHL 3
TgenePAMchr5:102345529chr5:102353088ENST00000304400025670_7140975.0RepeatNote=NHL 4
TgenePAMchr5:102345529chr5:102353088ENST00000304400025766_8090975.0RepeatNote=NHL 5
TgenePAMchr5:102345529chr5:102353088ENST00000346918023498_5410888.0RepeatNote=NHL 1
TgenePAMchr5:102345529chr5:102353088ENST00000346918023567_6080888.0RepeatNote=NHL 2
TgenePAMchr5:102345529chr5:102353088ENST00000346918023617_6620888.0RepeatNote=NHL 3
TgenePAMchr5:102345529chr5:102353088ENST00000346918023670_7140888.0RepeatNote=NHL 4
TgenePAMchr5:102345529chr5:102353088ENST00000346918023766_8090888.0RepeatNote=NHL 5
TgenePAMchr5:102345529chr5:102353088ENST00000348126024498_5410867.0RepeatNote=NHL 1
TgenePAMchr5:102345529chr5:102353088ENST00000348126024567_6080867.0RepeatNote=NHL 2
TgenePAMchr5:102345529chr5:102353088ENST00000348126024617_6620867.0RepeatNote=NHL 3
TgenePAMchr5:102345529chr5:102353088ENST00000348126024670_7140867.0RepeatNote=NHL 4
TgenePAMchr5:102345529chr5:102353088ENST00000348126024766_8090867.0RepeatNote=NHL 5
TgenePAMchr5:102345529chr5:102353088ENST00000438793025498_5410974.0RepeatNote=NHL 1
TgenePAMchr5:102345529chr5:102353088ENST00000438793025567_6080974.0RepeatNote=NHL 2
TgenePAMchr5:102345529chr5:102353088ENST00000438793025617_6620974.0RepeatNote=NHL 3
TgenePAMchr5:102345529chr5:102353088ENST00000438793025670_7140974.0RepeatNote=NHL 4
TgenePAMchr5:102345529chr5:102353088ENST00000438793025766_8090974.0RepeatNote=NHL 5
TgenePAMchr5:102345529chr5:102353088ENST00000455264024498_5410906.0RepeatNote=NHL 1
TgenePAMchr5:102345529chr5:102353088ENST00000455264024567_6080906.0RepeatNote=NHL 2
TgenePAMchr5:102345529chr5:102353088ENST00000455264024617_6620906.0RepeatNote=NHL 3
TgenePAMchr5:102345529chr5:102353088ENST00000455264024670_7140906.0RepeatNote=NHL 4
TgenePAMchr5:102345529chr5:102353088ENST00000455264024766_8090906.0RepeatNote=NHL 5
TgenePAMchr5:102363943chr5:102364762ENST00000304400025498_5410975.0RepeatNote=NHL 1
TgenePAMchr5:102363943chr5:102364762ENST00000304400025567_6080975.0RepeatNote=NHL 2
TgenePAMchr5:102363943chr5:102364762ENST00000304400025617_6620975.0RepeatNote=NHL 3
TgenePAMchr5:102363943chr5:102364762ENST00000304400025670_7140975.0RepeatNote=NHL 4
TgenePAMchr5:102363943chr5:102364762ENST00000304400025766_8090975.0RepeatNote=NHL 5
TgenePAMchr5:102363943chr5:102364762ENST00000346918023498_5410888.0RepeatNote=NHL 1
TgenePAMchr5:102363943chr5:102364762ENST00000346918023567_6080888.0RepeatNote=NHL 2
TgenePAMchr5:102363943chr5:102364762ENST00000346918023617_6620888.0RepeatNote=NHL 3
TgenePAMchr5:102363943chr5:102364762ENST00000346918023670_7140888.0RepeatNote=NHL 4
TgenePAMchr5:102363943chr5:102364762ENST00000346918023766_8090888.0RepeatNote=NHL 5
TgenePAMchr5:102363943chr5:102364762ENST00000348126024498_5410867.0RepeatNote=NHL 1
TgenePAMchr5:102363943chr5:102364762ENST00000348126024567_6080867.0RepeatNote=NHL 2
TgenePAMchr5:102363943chr5:102364762ENST00000348126024617_6620867.0RepeatNote=NHL 3
TgenePAMchr5:102363943chr5:102364762ENST00000348126024670_7140867.0RepeatNote=NHL 4
TgenePAMchr5:102363943chr5:102364762ENST00000348126024766_8090867.0RepeatNote=NHL 5
TgenePAMchr5:102363943chr5:102364762ENST00000438793025498_5410974.0RepeatNote=NHL 1
TgenePAMchr5:102363943chr5:102364762ENST00000438793025567_6080974.0RepeatNote=NHL 2
TgenePAMchr5:102363943chr5:102364762ENST00000438793025617_6620974.0RepeatNote=NHL 3
TgenePAMchr5:102363943chr5:102364762ENST00000438793025670_7140974.0RepeatNote=NHL 4
TgenePAMchr5:102363943chr5:102364762ENST00000438793025766_8090974.0RepeatNote=NHL 5
TgenePAMchr5:102363943chr5:102364762ENST00000455264024498_5410906.0RepeatNote=NHL 1
TgenePAMchr5:102363943chr5:102364762ENST00000455264024567_6080906.0RepeatNote=NHL 2
TgenePAMchr5:102363943chr5:102364762ENST00000455264024617_6620906.0RepeatNote=NHL 3
TgenePAMchr5:102363943chr5:102364762ENST00000455264024670_7140906.0RepeatNote=NHL 4
TgenePAMchr5:102363943chr5:102364762ENST00000455264024766_8090906.0RepeatNote=NHL 5
TgenePAMchr5:102345529chr5:102353088ENST0000030440002531_8630975.0Topological domainIntragranular
TgenePAMchr5:102345529chr5:102353088ENST00000304400025888_9730975.0Topological domainCytoplasmic
TgenePAMchr5:102345529chr5:102353088ENST0000034691802331_8630888.0Topological domainIntragranular
TgenePAMchr5:102345529chr5:102353088ENST00000346918023888_9730888.0Topological domainCytoplasmic
TgenePAMchr5:102345529chr5:102353088ENST0000034812602431_8630867.0Topological domainIntragranular
TgenePAMchr5:102345529chr5:102353088ENST00000348126024888_9730867.0Topological domainCytoplasmic
TgenePAMchr5:102345529chr5:102353088ENST0000043879302531_8630974.0Topological domainIntragranular
TgenePAMchr5:102345529chr5:102353088ENST00000438793025888_9730974.0Topological domainCytoplasmic
TgenePAMchr5:102345529chr5:102353088ENST0000045526402431_8630906.0Topological domainIntragranular
TgenePAMchr5:102345529chr5:102353088ENST00000455264024888_9730906.0Topological domainCytoplasmic
TgenePAMchr5:102363943chr5:102364762ENST0000030440002531_8630975.0Topological domainIntragranular
TgenePAMchr5:102363943chr5:102364762ENST00000304400025888_9730975.0Topological domainCytoplasmic
TgenePAMchr5:102363943chr5:102364762ENST0000034691802331_8630888.0Topological domainIntragranular
TgenePAMchr5:102363943chr5:102364762ENST00000346918023888_9730888.0Topological domainCytoplasmic
TgenePAMchr5:102363943chr5:102364762ENST0000034812602431_8630867.0Topological domainIntragranular
TgenePAMchr5:102363943chr5:102364762ENST00000348126024888_9730867.0Topological domainCytoplasmic
TgenePAMchr5:102363943chr5:102364762ENST0000043879302531_8630974.0Topological domainIntragranular
TgenePAMchr5:102363943chr5:102364762ENST00000438793025888_9730974.0Topological domainCytoplasmic
TgenePAMchr5:102363943chr5:102364762ENST0000045526402431_8630906.0Topological domainIntragranular
TgenePAMchr5:102363943chr5:102364762ENST00000455264024888_9730906.0Topological domainCytoplasmic
TgenePAMchr5:102345529chr5:102353088ENST00000304400025864_8870975.0TransmembraneHelical
TgenePAMchr5:102345529chr5:102353088ENST00000346918023864_8870888.0TransmembraneHelical
TgenePAMchr5:102345529chr5:102353088ENST00000348126024864_8870867.0TransmembraneHelical
TgenePAMchr5:102345529chr5:102353088ENST00000438793025864_8870974.0TransmembraneHelical
TgenePAMchr5:102345529chr5:102353088ENST00000455264024864_8870906.0TransmembraneHelical
TgenePAMchr5:102363943chr5:102364762ENST00000304400025864_8870975.0TransmembraneHelical
TgenePAMchr5:102363943chr5:102364762ENST00000346918023864_8870888.0TransmembraneHelical
TgenePAMchr5:102363943chr5:102364762ENST00000348126024864_8870867.0TransmembraneHelical
TgenePAMchr5:102363943chr5:102364762ENST00000438793025864_8870974.0TransmembraneHelical
TgenePAMchr5:102363943chr5:102364762ENST00000455264024864_8870906.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePAMchr5:102345529chr5:102353088ENST00000304400-1251_4940975.0RegionPeptidylglycine alpha-hydroxylating monooxygenase
HgenePAMchr5:102345529chr5:102353088ENST00000304400-125495_8170975.0RegionPeptidyl-alpha-hydroxyglycine alpha-amidating lyase
HgenePAMchr5:102345529chr5:102353088ENST00000346918-1231_4940888.0RegionPeptidylglycine alpha-hydroxylating monooxygenase
HgenePAMchr5:102345529chr5:102353088ENST00000346918-123495_8170888.0RegionPeptidyl-alpha-hydroxyglycine alpha-amidating lyase
HgenePAMchr5:102345529chr5:102353088ENST00000348126-1241_4940867.0RegionPeptidylglycine alpha-hydroxylating monooxygenase
HgenePAMchr5:102345529chr5:102353088ENST00000348126-124495_8170867.0RegionPeptidyl-alpha-hydroxyglycine alpha-amidating lyase
HgenePAMchr5:102345529chr5:102353088ENST00000438793-1251_4940974.0RegionPeptidylglycine alpha-hydroxylating monooxygenase
HgenePAMchr5:102345529chr5:102353088ENST00000438793-125495_8170974.0RegionPeptidyl-alpha-hydroxyglycine alpha-amidating lyase
HgenePAMchr5:102345529chr5:102353088ENST00000455264-1241_4940906.0RegionPeptidylglycine alpha-hydroxylating monooxygenase
HgenePAMchr5:102345529chr5:102353088ENST00000455264-124495_8170906.0RegionPeptidyl-alpha-hydroxyglycine alpha-amidating lyase
HgenePAMchr5:102363943chr5:102364762ENST00000346918+1231_4940888.0RegionPeptidylglycine alpha-hydroxylating monooxygenase
HgenePAMchr5:102363943chr5:102364762ENST00000346918+123495_8170888.0RegionPeptidyl-alpha-hydroxyglycine alpha-amidating lyase
HgenePAMchr5:102363943chr5:102364762ENST00000348126+2324495_817807.3333333333334867.0RegionPeptidyl-alpha-hydroxyglycine alpha-amidating lyase
HgenePAMchr5:102345529chr5:102353088ENST00000304400-125498_5410975.0RepeatNote=NHL 1
HgenePAMchr5:102345529chr5:102353088ENST00000304400-125567_6080975.0RepeatNote=NHL 2
HgenePAMchr5:102345529chr5:102353088ENST00000304400-125617_6620975.0RepeatNote=NHL 3
HgenePAMchr5:102345529chr5:102353088ENST00000304400-125670_7140975.0RepeatNote=NHL 4
HgenePAMchr5:102345529chr5:102353088ENST00000304400-125766_8090975.0RepeatNote=NHL 5
HgenePAMchr5:102345529chr5:102353088ENST00000346918-123498_5410888.0RepeatNote=NHL 1
HgenePAMchr5:102345529chr5:102353088ENST00000346918-123567_6080888.0RepeatNote=NHL 2
HgenePAMchr5:102345529chr5:102353088ENST00000346918-123617_6620888.0RepeatNote=NHL 3
HgenePAMchr5:102345529chr5:102353088ENST00000346918-123670_7140888.0RepeatNote=NHL 4
HgenePAMchr5:102345529chr5:102353088ENST00000346918-123766_8090888.0RepeatNote=NHL 5
HgenePAMchr5:102345529chr5:102353088ENST00000348126-124498_5410867.0RepeatNote=NHL 1
HgenePAMchr5:102345529chr5:102353088ENST00000348126-124567_6080867.0RepeatNote=NHL 2
HgenePAMchr5:102345529chr5:102353088ENST00000348126-124617_6620867.0RepeatNote=NHL 3
HgenePAMchr5:102345529chr5:102353088ENST00000348126-124670_7140867.0RepeatNote=NHL 4
HgenePAMchr5:102345529chr5:102353088ENST00000348126-124766_8090867.0RepeatNote=NHL 5
HgenePAMchr5:102345529chr5:102353088ENST00000438793-125498_5410974.0RepeatNote=NHL 1
HgenePAMchr5:102345529chr5:102353088ENST00000438793-125567_6080974.0RepeatNote=NHL 2
HgenePAMchr5:102345529chr5:102353088ENST00000438793-125617_6620974.0RepeatNote=NHL 3
HgenePAMchr5:102345529chr5:102353088ENST00000438793-125670_7140974.0RepeatNote=NHL 4
HgenePAMchr5:102345529chr5:102353088ENST00000438793-125766_8090974.0RepeatNote=NHL 5
HgenePAMchr5:102345529chr5:102353088ENST00000455264-124498_5410906.0RepeatNote=NHL 1
HgenePAMchr5:102345529chr5:102353088ENST00000455264-124567_6080906.0RepeatNote=NHL 2
HgenePAMchr5:102345529chr5:102353088ENST00000455264-124617_6620906.0RepeatNote=NHL 3
HgenePAMchr5:102345529chr5:102353088ENST00000455264-124670_7140906.0RepeatNote=NHL 4
HgenePAMchr5:102345529chr5:102353088ENST00000455264-124766_8090906.0RepeatNote=NHL 5
HgenePAMchr5:102363943chr5:102364762ENST00000346918+123498_5410888.0RepeatNote=NHL 1
HgenePAMchr5:102363943chr5:102364762ENST00000346918+123567_6080888.0RepeatNote=NHL 2
HgenePAMchr5:102363943chr5:102364762ENST00000346918+123617_6620888.0RepeatNote=NHL 3
HgenePAMchr5:102363943chr5:102364762ENST00000346918+123670_7140888.0RepeatNote=NHL 4
HgenePAMchr5:102363943chr5:102364762ENST00000346918+123766_8090888.0RepeatNote=NHL 5
HgenePAMchr5:102345529chr5:102353088ENST00000304400-12531_8630975.0Topological domainIntragranular
HgenePAMchr5:102345529chr5:102353088ENST00000304400-125888_9730975.0Topological domainCytoplasmic
HgenePAMchr5:102345529chr5:102353088ENST00000346918-12331_8630888.0Topological domainIntragranular
HgenePAMchr5:102345529chr5:102353088ENST00000346918-123888_9730888.0Topological domainCytoplasmic
HgenePAMchr5:102345529chr5:102353088ENST00000348126-12431_8630867.0Topological domainIntragranular
HgenePAMchr5:102345529chr5:102353088ENST00000348126-124888_9730867.0Topological domainCytoplasmic
HgenePAMchr5:102345529chr5:102353088ENST00000438793-12531_8630974.0Topological domainIntragranular
HgenePAMchr5:102345529chr5:102353088ENST00000438793-125888_9730974.0Topological domainCytoplasmic
HgenePAMchr5:102345529chr5:102353088ENST00000455264-12431_8630906.0Topological domainIntragranular
HgenePAMchr5:102345529chr5:102353088ENST00000455264-124888_9730906.0Topological domainCytoplasmic
HgenePAMchr5:102363943chr5:102364762ENST00000304400+2425888_973915.3333333333334975.0Topological domainCytoplasmic
HgenePAMchr5:102363943chr5:102364762ENST00000346918+12331_8630888.0Topological domainIntragranular
HgenePAMchr5:102363943chr5:102364762ENST00000346918+123888_9730888.0Topological domainCytoplasmic
HgenePAMchr5:102363943chr5:102364762ENST00000348126+232431_863807.3333333333334867.0Topological domainIntragranular
HgenePAMchr5:102363943chr5:102364762ENST00000348126+2324888_973807.3333333333334867.0Topological domainCytoplasmic
HgenePAMchr5:102363943chr5:102364762ENST00000438793+2425888_973914.3333333333334974.0Topological domainCytoplasmic
HgenePAMchr5:102363943chr5:102364762ENST00000455264+232431_863846.3333333333334906.0Topological domainIntragranular
HgenePAMchr5:102363943chr5:102364762ENST00000455264+2324888_973846.3333333333334906.0Topological domainCytoplasmic
HgenePAMchr5:102345529chr5:102353088ENST00000304400-125864_8870975.0TransmembraneHelical
HgenePAMchr5:102345529chr5:102353088ENST00000346918-123864_8870888.0TransmembraneHelical
HgenePAMchr5:102345529chr5:102353088ENST00000348126-124864_8870867.0TransmembraneHelical
HgenePAMchr5:102345529chr5:102353088ENST00000438793-125864_8870974.0TransmembraneHelical
HgenePAMchr5:102345529chr5:102353088ENST00000455264-124864_8870906.0TransmembraneHelical
HgenePAMchr5:102363943chr5:102364762ENST00000346918+123864_8870888.0TransmembraneHelical
HgenePAMchr5:102363943chr5:102364762ENST00000348126+2324864_887807.3333333333334867.0TransmembraneHelical
HgenePAMchr5:102363943chr5:102364762ENST00000455264+2324864_887846.3333333333334906.0TransmembraneHelical


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Fusion Gene Sequence for PAM-PAM


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

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Fusion Gene PPI Analysis for PAM-PAM


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgenePAMchr5:102345529chr5:102353088ENST00000304400025925_9420975.0RASSF9
TgenePAMchr5:102345529chr5:102353088ENST00000346918023925_9420888.0RASSF9
TgenePAMchr5:102345529chr5:102353088ENST00000348126024925_9420867.0RASSF9
TgenePAMchr5:102345529chr5:102353088ENST00000438793025925_9420974.0RASSF9
TgenePAMchr5:102345529chr5:102353088ENST00000455264024925_9420906.0RASSF9
TgenePAMchr5:102363943chr5:102364762ENST00000304400025925_9420975.0RASSF9
TgenePAMchr5:102363943chr5:102364762ENST00000346918023925_9420888.0RASSF9
TgenePAMchr5:102363943chr5:102364762ENST00000348126024925_9420867.0RASSF9
TgenePAMchr5:102363943chr5:102364762ENST00000438793025925_9420974.0RASSF9
TgenePAMchr5:102363943chr5:102364762ENST00000455264024925_9420906.0RASSF9


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgenePAMchr5:102345529chr5:102353088ENST00000304400-125925_9420975.0RASSF9
HgenePAMchr5:102345529chr5:102353088ENST00000346918-123925_9420888.0RASSF9
HgenePAMchr5:102345529chr5:102353088ENST00000348126-124925_9420867.0RASSF9
HgenePAMchr5:102345529chr5:102353088ENST00000438793-125925_9420974.0RASSF9
HgenePAMchr5:102345529chr5:102353088ENST00000455264-124925_9420906.0RASSF9
HgenePAMchr5:102363943chr5:102364762ENST00000304400+2425925_942915.3333333333334975.0RASSF9
HgenePAMchr5:102363943chr5:102364762ENST00000346918+123925_9420888.0RASSF9
HgenePAMchr5:102363943chr5:102364762ENST00000348126+2324925_942807.3333333333334867.0RASSF9
HgenePAMchr5:102363943chr5:102364762ENST00000438793+2425925_942914.3333333333334974.0RASSF9
HgenePAMchr5:102363943chr5:102364762ENST00000455264+2324925_942846.3333333333334906.0RASSF9


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for PAM-PAM


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for PAM-PAM


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgenePAMC0011860Diabetes Mellitus, Non-Insulin-Dependent2CTD_human
HgenePAMC0003469Anxiety Disorders1CTD_human
HgenePAMC0022333Jacksonian Seizure1CTD_human
HgenePAMC0036572Seizures1CTD_human
HgenePAMC0149958Complex partial seizures1CTD_human
HgenePAMC0234533Generalized seizures1CTD_human
HgenePAMC0234535Clonic Seizures1CTD_human
HgenePAMC0270824Visual seizure1CTD_human
HgenePAMC0270844Tonic Seizures1CTD_human
HgenePAMC0270846Epileptic drop attack1CTD_human
HgenePAMC0376280Anxiety States, Neurotic1CTD_human
HgenePAMC0422850Seizures, Somatosensory1CTD_human
HgenePAMC0422852Seizures, Auditory1CTD_human
HgenePAMC0422853Olfactory seizure1CTD_human
HgenePAMC0422854Gustatory seizure1CTD_human
HgenePAMC0422855Vertiginous seizure1CTD_human
HgenePAMC0494475Tonic - clonic seizures1CTD_human
HgenePAMC0751056Non-epileptic convulsion1CTD_human
HgenePAMC0751110Single Seizure1CTD_human
HgenePAMC0751123Atonic Absence Seizures1CTD_human
HgenePAMC0751494Convulsive Seizures1CTD_human
HgenePAMC0751495Seizures, Focal1CTD_human
HgenePAMC0751496Seizures, Sensory1CTD_human
HgenePAMC1279420Anxiety neurosis (finding)1CTD_human
HgenePAMC3495874Nonepileptic Seizures1CTD_human
HgenePAMC4048158Convulsions1CTD_human
HgenePAMC4316903Absence Seizures1CTD_human
HgenePAMC4317109Epileptic Seizures1CTD_human
HgenePAMC4317123Myoclonic Seizures1CTD_human
HgenePAMC4505436Generalized Absence Seizures1CTD_human
TgenePAMC0011860Diabetes Mellitus, Non-Insulin-Dependent2CTD_human
TgenePAMC0003469Anxiety Disorders1CTD_human
TgenePAMC0022333Jacksonian Seizure1CTD_human
TgenePAMC0036572Seizures1CTD_human
TgenePAMC0149958Complex partial seizures1CTD_human
TgenePAMC0234533Generalized seizures1CTD_human
TgenePAMC0234535Clonic Seizures1CTD_human
TgenePAMC0270824Visual seizure1CTD_human
TgenePAMC0270844Tonic Seizures1CTD_human
TgenePAMC0270846Epileptic drop attack1CTD_human
TgenePAMC0376280Anxiety States, Neurotic1CTD_human
TgenePAMC0422850Seizures, Somatosensory1CTD_human
TgenePAMC0422852Seizures, Auditory1CTD_human
TgenePAMC0422853Olfactory seizure1CTD_human
TgenePAMC0422854Gustatory seizure1CTD_human
TgenePAMC0422855Vertiginous seizure1CTD_human
TgenePAMC0494475Tonic - clonic seizures1CTD_human
TgenePAMC0751056Non-epileptic convulsion1CTD_human
TgenePAMC0751110Single Seizure1CTD_human
TgenePAMC0751123Atonic Absence Seizures1CTD_human
TgenePAMC0751494Convulsive Seizures1CTD_human
TgenePAMC0751495Seizures, Focal1CTD_human
TgenePAMC0751496Seizures, Sensory1CTD_human
TgenePAMC1279420Anxiety neurosis (finding)1CTD_human
TgenePAMC3495874Nonepileptic Seizures1CTD_human
TgenePAMC4048158Convulsions1CTD_human
TgenePAMC4316903Absence Seizures1CTD_human
TgenePAMC4317109Epileptic Seizures1CTD_human
TgenePAMC4317123Myoclonic Seizures1CTD_human
TgenePAMC4505436Generalized Absence Seizures1CTD_human