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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:PDCD6-TERT (FusionGDB2 ID:63206)

Fusion Gene Summary for PDCD6-TERT

check button Fusion gene summary
Fusion gene informationFusion gene name: PDCD6-TERT
Fusion gene ID: 63206
HgeneTgene
Gene symbol

PDCD6

TERT

Gene ID

10016

7015

Gene nameprogrammed cell death 6telomerase reverse transcriptase
SynonymsALG-2|ALG2|PEF1BCMM9|DKCA2|DKCB4|EST2|PFBMFT1|TCS1|TP2|TRT|hEST2|hTRT
Cytomap

5p15.33

5p15.33

Type of geneprotein-codingprotein-coding
Descriptionprogrammed cell death protein 6apoptosis-linked gene 2 proteinapoptosis-linked gene 2 protein homologprobable calcium-binding protein ALG-2telomerase reverse transcriptasetelomerase catalytic subunittelomerase-associated protein 2
Modification date2020031320200329
UniProtAcc

O75340

.
Ensembl transtripts involved in fusion geneENST00000264933, ENST00000505221, 
ENST00000509581, ENST00000507528, 
ENST00000511482, 		ENST00000310581, 
ENST00000296820, ENST00000334602, 
ENST00000508104, ENST00000522877, 
Fusion gene scores* DoF score3 X 2 X 4=2422 X 7 X 15=2310
# samples 431
** MAII scorelog2(4/24*10)=0.736965594166206
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(31/2310*10)=-2.89755273102918
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: PDCD6 [Title/Abstract] AND TERT [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointPDCD6(272887)-TERT(1282739), # samples:4
Anticipated loss of major functional domain due to fusion event.PDCD6-TERT seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgenePDCD6

GO:0001938

positive regulation of endothelial cell proliferation

21893193

HgenePDCD6

GO:0006886

intracellular protein transport

21122810

HgenePDCD6

GO:0010595

positive regulation of endothelial cell migration

21893193

HgenePDCD6

GO:0030948

negative regulation of vascular endothelial growth factor receptor signaling pathway

21893193

HgenePDCD6

GO:0032007

negative regulation of TOR signaling

21893193

HgenePDCD6

GO:0034605

cellular response to heat

21122810

HgenePDCD6

GO:0036324

vascular endothelial growth factor receptor-2 signaling pathway

21893193

HgenePDCD6

GO:0043280

positive regulation of cysteine-type endopeptidase activity involved in apoptotic process

16132846

HgenePDCD6

GO:0045766

positive regulation of angiogenesis

21893193

HgenePDCD6

GO:0051898

negative regulation of protein kinase B signaling

21893193

TgeneTERT

GO:0001172

transcription, RNA-templated

19701182

TgeneTERT

GO:0006278

RNA-dependent DNA biosynthetic process

9398860

TgeneTERT

GO:0007004

telomere maintenance via telomerase

9443919|16043710|17940095|19701182|21531765|29695869

TgeneTERT

GO:0007005

mitochondrion organization

21937513

TgeneTERT

GO:0010629

negative regulation of gene expression

11927518

TgeneTERT

GO:0022616

DNA strand elongation

16043710

TgeneTERT

GO:0030422

production of siRNA involved in RNA interference

19701182

TgeneTERT

GO:0031647

regulation of protein stability

24415760|26194824

TgeneTERT

GO:0032092

positive regulation of protein binding

24415760

TgeneTERT

GO:0051000

positive regulation of nitric-oxide synthase activity

11927518

TgeneTERT

GO:0070200

establishment of protein localization to telomere

25589350

TgeneTERT

GO:0071897

DNA biosynthetic process

9398860|19701182

TgeneTERT

GO:1903704

negative regulation of production of siRNA involved in RNA interference

19701182

TgeneTERT

GO:1904751

positive regulation of protein localization to nucleolus

24415760

TgeneTERT

GO:2000773

negative regulation of cellular senescence

11927518


check buttonFusion gene breakpoints across PDCD6 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across TERT (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4KICHTCGA-KN-8435-01APDCD6chr5

271936

+TERTchr5

1282739

-
ChimerDB4KIRCTCGA-BP-4991-01APDCD6chr5

272887

+TERTchr5

1282739

-
ChimerDB4KIRCTCGA-BP-4991PDCD6chr5

272887

+TERTchr5

1282739

-
ChimerDB4KIRCTCGA-BP-4991-01APDCD6chr5

272887

+TERTchr5

1282739

-
ChimerDB4KIRCTCGA-BP-4991-01APDCD6chr5

272887

-TERTchr5

1282739

-
ChimerDB4KICHTCGA-KN-8435-01APDCD6chr5

271936

-TERTchr5

1294781

-


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Fusion Gene ORF analysis for PDCD6-TERT

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000264933ENST00000310581PDCD6chr5

271936

+TERTchr5

1282739

-
Frame-shiftENST00000264933ENST00000296820PDCD6chr5

271936

+TERTchr5

1282739

-
Frame-shiftENST00000264933ENST00000334602PDCD6chr5

271936

+TERTchr5

1282739

-
Frame-shiftENST00000264933ENST00000508104PDCD6chr5

271936

+TERTchr5

1282739

-
5CDS-intronENST00000264933ENST00000522877PDCD6chr5

271936

+TERTchr5

1282739

-
Frame-shiftENST00000505221ENST00000310581PDCD6chr5

271936

+TERTchr5

1282739

-
Frame-shiftENST00000505221ENST00000296820PDCD6chr5

271936

+TERTchr5

1282739

-
Frame-shiftENST00000505221ENST00000334602PDCD6chr5

271936

+TERTchr5

1282739

-
Frame-shiftENST00000505221ENST00000508104PDCD6chr5

271936

+TERTchr5

1282739

-
5CDS-intronENST00000505221ENST00000522877PDCD6chr5

271936

+TERTchr5

1282739

-
Frame-shiftENST00000509581ENST00000310581PDCD6chr5

271936

+TERTchr5

1282739

-
Frame-shiftENST00000509581ENST00000296820PDCD6chr5

271936

+TERTchr5

1282739

-
Frame-shiftENST00000509581ENST00000334602PDCD6chr5

271936

+TERTchr5

1282739

-
Frame-shiftENST00000509581ENST00000508104PDCD6chr5

271936

+TERTchr5

1282739

-
5CDS-intronENST00000509581ENST00000522877PDCD6chr5

271936

+TERTchr5

1282739

-
Frame-shiftENST00000507528ENST00000310581PDCD6chr5

271936

+TERTchr5

1282739

-
Frame-shiftENST00000507528ENST00000296820PDCD6chr5

271936

+TERTchr5

1282739

-
Frame-shiftENST00000507528ENST00000334602PDCD6chr5

271936

+TERTchr5

1282739

-
Frame-shiftENST00000507528ENST00000508104PDCD6chr5

271936

+TERTchr5

1282739

-
5CDS-intronENST00000507528ENST00000522877PDCD6chr5

271936

+TERTchr5

1282739

-
intron-3CDSENST00000511482ENST00000310581PDCD6chr5

271936

+TERTchr5

1282739

-
intron-3CDSENST00000511482ENST00000296820PDCD6chr5

271936

+TERTchr5

1282739

-
intron-3CDSENST00000511482ENST00000334602PDCD6chr5

271936

+TERTchr5

1282739

-
intron-3CDSENST00000511482ENST00000508104PDCD6chr5

271936

+TERTchr5

1282739

-
intron-intronENST00000511482ENST00000522877PDCD6chr5

271936

+TERTchr5

1282739

-
In-frameENST00000264933ENST00000310581PDCD6chr5

272887

+TERTchr5

1282739

-
Frame-shiftENST00000264933ENST00000296820PDCD6chr5

272887

+TERTchr5

1282739

-
In-frameENST00000264933ENST00000334602PDCD6chr5

272887

+TERTchr5

1282739

-
In-frameENST00000264933ENST00000508104PDCD6chr5

272887

+TERTchr5

1282739

-
5CDS-intronENST00000264933ENST00000522877PDCD6chr5

272887

+TERTchr5

1282739

-
In-frameENST00000505221ENST00000310581PDCD6chr5

272887

+TERTchr5

1282739

-
Frame-shiftENST00000505221ENST00000296820PDCD6chr5

272887

+TERTchr5

1282739

-
In-frameENST00000505221ENST00000334602PDCD6chr5

272887

+TERTchr5

1282739

-
In-frameENST00000505221ENST00000508104PDCD6chr5

272887

+TERTchr5

1282739

-
5CDS-intronENST00000505221ENST00000522877PDCD6chr5

272887

+TERTchr5

1282739

-
In-frameENST00000509581ENST00000310581PDCD6chr5

272887

+TERTchr5

1282739

-
Frame-shiftENST00000509581ENST00000296820PDCD6chr5

272887

+TERTchr5

1282739

-
In-frameENST00000509581ENST00000334602PDCD6chr5

272887

+TERTchr5

1282739

-
In-frameENST00000509581ENST00000508104PDCD6chr5

272887

+TERTchr5

1282739

-
5CDS-intronENST00000509581ENST00000522877PDCD6chr5

272887

+TERTchr5

1282739

-
In-frameENST00000507528ENST00000310581PDCD6chr5

272887

+TERTchr5

1282739

-
Frame-shiftENST00000507528ENST00000296820PDCD6chr5

272887

+TERTchr5

1282739

-
In-frameENST00000507528ENST00000334602PDCD6chr5

272887

+TERTchr5

1282739

-
In-frameENST00000507528ENST00000508104PDCD6chr5

272887

+TERTchr5

1282739

-
5CDS-intronENST00000507528ENST00000522877PDCD6chr5

272887

+TERTchr5

1282739

-
intron-3CDSENST00000511482ENST00000310581PDCD6chr5

272887

+TERTchr5

1282739

-
intron-3CDSENST00000511482ENST00000296820PDCD6chr5

272887

+TERTchr5

1282739

-
intron-3CDSENST00000511482ENST00000334602PDCD6chr5

272887

+TERTchr5

1282739

-
intron-3CDSENST00000511482ENST00000508104PDCD6chr5

272887

+TERTchr5

1282739

-
intron-intronENST00000511482ENST00000522877PDCD6chr5

272887

+TERTchr5

1282739

-
Frame-shiftENST00000264933ENST00000310581PDCD6chr5

271936

-TERTchr5

1294781

-
Frame-shiftENST00000264933ENST00000296820PDCD6chr5

271936

-TERTchr5

1294781

-
Frame-shiftENST00000264933ENST00000334602PDCD6chr5

271936

-TERTchr5

1294781

-
Frame-shiftENST00000264933ENST00000508104PDCD6chr5

271936

-TERTchr5

1294781

-
5CDS-5UTRENST00000264933ENST00000522877PDCD6chr5

271936

-TERTchr5

1294781

-
Frame-shiftENST00000505221ENST00000310581PDCD6chr5

271936

-TERTchr5

1294781

-
Frame-shiftENST00000505221ENST00000296820PDCD6chr5

271936

-TERTchr5

1294781

-
Frame-shiftENST00000505221ENST00000334602PDCD6chr5

271936

-TERTchr5

1294781

-
Frame-shiftENST00000505221ENST00000508104PDCD6chr5

271936

-TERTchr5

1294781

-
5CDS-5UTRENST00000505221ENST00000522877PDCD6chr5

271936

-TERTchr5

1294781

-
Frame-shiftENST00000509581ENST00000310581PDCD6chr5

271936

-TERTchr5

1294781

-
Frame-shiftENST00000509581ENST00000296820PDCD6chr5

271936

-TERTchr5

1294781

-
Frame-shiftENST00000509581ENST00000334602PDCD6chr5

271936

-TERTchr5

1294781

-
Frame-shiftENST00000509581ENST00000508104PDCD6chr5

271936

-TERTchr5

1294781

-
5CDS-5UTRENST00000509581ENST00000522877PDCD6chr5

271936

-TERTchr5

1294781

-
Frame-shiftENST00000507528ENST00000310581PDCD6chr5

271936

-TERTchr5

1294781

-
Frame-shiftENST00000507528ENST00000296820PDCD6chr5

271936

-TERTchr5

1294781

-
Frame-shiftENST00000507528ENST00000334602PDCD6chr5

271936

-TERTchr5

1294781

-
Frame-shiftENST00000507528ENST00000508104PDCD6chr5

271936

-TERTchr5

1294781

-
5CDS-5UTRENST00000507528ENST00000522877PDCD6chr5

271936

-TERTchr5

1294781

-
intron-3CDSENST00000511482ENST00000310581PDCD6chr5

271936

-TERTchr5

1294781

-
intron-3CDSENST00000511482ENST00000296820PDCD6chr5

271936

-TERTchr5

1294781

-
intron-3CDSENST00000511482ENST00000334602PDCD6chr5

271936

-TERTchr5

1294781

-
intron-3CDSENST00000511482ENST00000508104PDCD6chr5

271936

-TERTchr5

1294781

-
intron-5UTRENST00000511482ENST00000522877PDCD6chr5

271936

-TERTchr5

1294781

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000264933PDCD6chr5272887+ENST00000310581TERTchr51282739-265026342088694
ENST00000264933PDCD6chr5272887+ENST00000334602TERTchr51282739-190026341899632
ENST00000264933PDCD6chr5272887+ENST00000508104TERTchr51282739-117626341113369
ENST00000505221PDCD6chr5272887+ENST00000310581TERTchr51282739-2624237202062680
ENST00000505221PDCD6chr5272887+ENST00000334602TERTchr51282739-1874237201873618
ENST00000505221PDCD6chr5272887+ENST00000508104TERTchr51282739-1150237201087355
ENST00000509581PDCD6chr5272887+ENST00000310581TERTchr51282739-2614227102052680
ENST00000509581PDCD6chr5272887+ENST00000334602TERTchr51282739-1864227101863618
ENST00000509581PDCD6chr5272887+ENST00000508104TERTchr51282739-1140227101077355
ENST00000507528PDCD6chr5272887+ENST00000310581TERTchr51282739-2614227102052680
ENST00000507528PDCD6chr5272887+ENST00000334602TERTchr51282739-1864227101863618
ENST00000507528PDCD6chr5272887+ENST00000508104TERTchr51282739-1140227101077355

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000264933ENST00000310581PDCD6chr5272887+TERTchr51282739-0.025077330.97492266
ENST00000264933ENST00000334602PDCD6chr5272887+TERTchr51282739-0.0455858450.9544142
ENST00000264933ENST00000508104PDCD6chr5272887+TERTchr51282739-0.0887677150.91123235
ENST00000505221ENST00000310581PDCD6chr5272887+TERTchr51282739-0.0300876160.96991235
ENST00000505221ENST00000334602PDCD6chr5272887+TERTchr51282739-0.0478747040.9521254
ENST00000505221ENST00000508104PDCD6chr5272887+TERTchr51282739-0.052881590.9471184
ENST00000509581ENST00000310581PDCD6chr5272887+TERTchr51282739-0.029789850.9702102
ENST00000509581ENST00000334602PDCD6chr5272887+TERTchr51282739-0.048851030.951149
ENST00000509581ENST00000508104PDCD6chr5272887+TERTchr51282739-0.053732350.94626766
ENST00000507528ENST00000310581PDCD6chr5272887+TERTchr51282739-0.029789850.9702102
ENST00000507528ENST00000334602PDCD6chr5272887+TERTchr51282739-0.048851030.951149
ENST00000507528ENST00000508104PDCD6chr5272887+TERTchr51282739-0.053732350.94626766

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Fusion Genomic Features for PDCD6-TERT


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for PDCD6-TERT


check button Go to

FGviewer for the breakpoints of chr5:272887-chr5:1282739

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
PDCD6

O75340

.
FUNCTION: Calcium sensor that plays a key role in processes such as endoplasmic reticulum (ER)-Golgi vesicular transport, endosomal biogenesis or membrane repair. Acts as an adapter that bridges unrelated proteins or stabilizes weak protein-protein complexes in response to calcium: calcium-binding triggers exposure of apolar surface, promoting interaction with different sets of proteins thanks to 3 different hydrophobic pockets, leading to translocation to membranes (PubMed:20691033, PubMed:25667979). Involved in ER-Golgi transport by promoting the association between PDCD6IP and TSG101, thereby bridging together the ESCRT-III and ESCRT-I complexes (PubMed:19520058). Together with PEF1, acts as calcium-dependent adapter for the BCR(KLHL12) complex, a complex involved in ER-Golgi transport by regulating the size of COPII coats (PubMed:27716508). In response to cytosolic calcium increase, the heterodimer formed with PEF1 interacts with, and bridges together the BCR(KLHL12) complex and SEC31 (SEC31A or SEC31B), promoting monoubiquitination of SEC31 and subsequent collagen export, which is required for neural crest specification (PubMed:27716508). Involved in the regulation of the distribution and function of MCOLN1 in the endosomal pathway (PubMed:19864416). Promotes localization and polymerization of TFG at endoplasmic reticulum exit site (PubMed:27813252). Required for T-cell receptor-, Fas-, and glucocorticoid-induced apoptosis (By similarity). May mediate Ca(2+)-regulated signals along the death pathway: interaction with DAPK1 can accelerate apoptotic cell death by increasing caspase-3 activity (PubMed:16132846). Its role in apoptosis may however be indirect, as suggested by knockout experiments (By similarity). May inhibit KDR/VEGFR2-dependent angiogenesis; the function involves inhibition of VEGF-induced phosphorylation of the Akt signaling pathway (PubMed:21893193). In case of infection by HIV-1 virus, indirectly inhibits HIV-1 production by affecting viral Gag expression and distribution (PubMed:27784779). {ECO:0000250|UniProtKB:P12815, ECO:0000269|PubMed:16132846, ECO:0000269|PubMed:19520058, ECO:0000269|PubMed:19864416, ECO:0000269|PubMed:20691033, ECO:0000269|PubMed:21893193, ECO:0000269|PubMed:25667979, ECO:0000269|PubMed:27716508, ECO:0000269|PubMed:27784779, ECO:0000269|PubMed:27813252}.; FUNCTION: [Isoform 2]: Has a lower Ca(2+) affinity than isoform 1 (By similarity). {ECO:0000250|UniProtKB:P12815}.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePDCD6chr5:272887chr5:1282739ENST00000264933+2636_4754.333333333333336192.0Calcium binding1
HgenePDCD6chr5:272887chr5:1282739ENST00000505221+2436_4754.33333333333333670.0Calcium binding1
HgenePDCD6chr5:272887chr5:1282739ENST00000507528+2636_4754.333333333333336190.0Calcium binding1
TgeneTERTchr5:272887chr5:1282739ENST00000296820114605_935524.3333333333334445.6666666666667DomainReverse transcriptase
TgeneTERTchr5:272887chr5:1282739ENST00000310581116605_935524.33333333333341133.0DomainReverse transcriptase
TgeneTERTchr5:272887chr5:1282739ENST00000334602115605_935524.33333333333341070.0DomainReverse transcriptase
TgeneTERTchr5:272887chr5:1282739ENST0000050810418605_935524.3333333333334808.0DomainReverse transcriptase
TgeneTERTchr5:272887chr5:1282739ENST00000296820114914_928524.3333333333334445.6666666666667RegionNote=Required for oligomerization
TgeneTERTchr5:272887chr5:1282739ENST00000296820114936_1132524.3333333333334445.6666666666667RegionNote=CTE
TgeneTERTchr5:272887chr5:1282739ENST00000310581116914_928524.33333333333341133.0RegionNote=Required for oligomerization
TgeneTERTchr5:272887chr5:1282739ENST00000310581116936_1132524.33333333333341133.0RegionNote=CTE
TgeneTERTchr5:272887chr5:1282739ENST00000334602115914_928524.33333333333341070.0RegionNote=Required for oligomerization
TgeneTERTchr5:272887chr5:1282739ENST00000334602115936_1132524.33333333333341070.0RegionNote=CTE
TgeneTERTchr5:272887chr5:1282739ENST0000050810418914_928524.3333333333334808.0RegionNote=Required for oligomerization
TgeneTERTchr5:272887chr5:1282739ENST0000050810418936_1132524.3333333333334808.0RegionNote=CTE

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePDCD6chr5:272887chr5:1282739ENST00000264933+26103_11454.333333333333336192.0Calcium binding3
HgenePDCD6chr5:272887chr5:1282739ENST00000264933+2673_8454.333333333333336192.0Calcium binding2
HgenePDCD6chr5:272887chr5:1282739ENST00000505221+24103_11454.33333333333333670.0Calcium binding3
HgenePDCD6chr5:272887chr5:1282739ENST00000505221+2473_8454.33333333333333670.0Calcium binding2
HgenePDCD6chr5:272887chr5:1282739ENST00000507528+26103_11454.333333333333336190.0Calcium binding3
HgenePDCD6chr5:272887chr5:1282739ENST00000507528+2673_8454.333333333333336190.0Calcium binding2
HgenePDCD6chr5:272887chr5:1282739ENST00000264933+26126_16154.333333333333336192.0DomainEF-hand 4
HgenePDCD6chr5:272887chr5:1282739ENST00000264933+26162_19154.333333333333336192.0DomainEF-hand 5
HgenePDCD6chr5:272887chr5:1282739ENST00000264933+2623_5854.333333333333336192.0DomainEF-hand 1
HgenePDCD6chr5:272887chr5:1282739ENST00000264933+2659_8954.333333333333336192.0DomainEF-hand 2
HgenePDCD6chr5:272887chr5:1282739ENST00000264933+2690_12554.333333333333336192.0DomainEF-hand 3
HgenePDCD6chr5:272887chr5:1282739ENST00000505221+24126_16154.33333333333333670.0DomainEF-hand 4
HgenePDCD6chr5:272887chr5:1282739ENST00000505221+24162_19154.33333333333333670.0DomainEF-hand 5
HgenePDCD6chr5:272887chr5:1282739ENST00000505221+2423_5854.33333333333333670.0DomainEF-hand 1
HgenePDCD6chr5:272887chr5:1282739ENST00000505221+2459_8954.33333333333333670.0DomainEF-hand 2
HgenePDCD6chr5:272887chr5:1282739ENST00000505221+2490_12554.33333333333333670.0DomainEF-hand 3
HgenePDCD6chr5:272887chr5:1282739ENST00000507528+26126_16154.333333333333336190.0DomainEF-hand 4
HgenePDCD6chr5:272887chr5:1282739ENST00000507528+26162_19154.333333333333336190.0DomainEF-hand 5
HgenePDCD6chr5:272887chr5:1282739ENST00000507528+2623_5854.333333333333336190.0DomainEF-hand 1
HgenePDCD6chr5:272887chr5:1282739ENST00000507528+2659_8954.333333333333336190.0DomainEF-hand 2
HgenePDCD6chr5:272887chr5:1282739ENST00000507528+2690_12554.333333333333336190.0DomainEF-hand 3
TgeneTERTchr5:272887chr5:1282739ENST00000296820114222_240524.3333333333334445.6666666666667MotifNote=Bipartite nuclear localization signal
TgeneTERTchr5:272887chr5:1282739ENST00000296820114328_333524.3333333333334445.6666666666667MotifTFLY%3B involved in RNA binding
TgeneTERTchr5:272887chr5:1282739ENST00000310581116222_240524.33333333333341133.0MotifNote=Bipartite nuclear localization signal
TgeneTERTchr5:272887chr5:1282739ENST00000310581116328_333524.33333333333341133.0MotifTFLY%3B involved in RNA binding
TgeneTERTchr5:272887chr5:1282739ENST00000334602115222_240524.33333333333341070.0MotifNote=Bipartite nuclear localization signal
TgeneTERTchr5:272887chr5:1282739ENST00000334602115328_333524.33333333333341070.0MotifTFLY%3B involved in RNA binding
TgeneTERTchr5:272887chr5:1282739ENST0000050810418222_240524.3333333333334808.0MotifNote=Bipartite nuclear localization signal
TgeneTERTchr5:272887chr5:1282739ENST0000050810418328_333524.3333333333334808.0MotifTFLY%3B involved in RNA binding
TgeneTERTchr5:272887chr5:1282739ENST000002968201141_230524.3333333333334445.6666666666667RegionNote=RNA-interacting domain 1
TgeneTERTchr5:272887chr5:1282739ENST00000296820114231_324524.3333333333334445.6666666666667RegionNote=Linker
TgeneTERTchr5:272887chr5:1282739ENST00000296820114301_538524.3333333333334445.6666666666667RegionNote=Required for oligomerization
TgeneTERTchr5:272887chr5:1282739ENST00000296820114325_550524.3333333333334445.6666666666667RegionNote=RNA-interacting domain 2
TgeneTERTchr5:272887chr5:1282739ENST00000296820114376_521524.3333333333334445.6666666666667RegionNote=QFP motif
TgeneTERTchr5:272887chr5:1282739ENST00000296820114397_417524.3333333333334445.6666666666667RegionNote=CP motif
TgeneTERTchr5:272887chr5:1282739ENST0000029682011458_197524.3333333333334445.6666666666667RegionNote=GQ motif
TgeneTERTchr5:272887chr5:1282739ENST000003105811161_230524.33333333333341133.0RegionNote=RNA-interacting domain 1
TgeneTERTchr5:272887chr5:1282739ENST00000310581116231_324524.33333333333341133.0RegionNote=Linker
TgeneTERTchr5:272887chr5:1282739ENST00000310581116301_538524.33333333333341133.0RegionNote=Required for oligomerization
TgeneTERTchr5:272887chr5:1282739ENST00000310581116325_550524.33333333333341133.0RegionNote=RNA-interacting domain 2
TgeneTERTchr5:272887chr5:1282739ENST00000310581116376_521524.33333333333341133.0RegionNote=QFP motif
TgeneTERTchr5:272887chr5:1282739ENST00000310581116397_417524.33333333333341133.0RegionNote=CP motif
TgeneTERTchr5:272887chr5:1282739ENST0000031058111658_197524.33333333333341133.0RegionNote=GQ motif
TgeneTERTchr5:272887chr5:1282739ENST000003346021151_230524.33333333333341070.0RegionNote=RNA-interacting domain 1
TgeneTERTchr5:272887chr5:1282739ENST00000334602115231_324524.33333333333341070.0RegionNote=Linker
TgeneTERTchr5:272887chr5:1282739ENST00000334602115301_538524.33333333333341070.0RegionNote=Required for oligomerization
TgeneTERTchr5:272887chr5:1282739ENST00000334602115325_550524.33333333333341070.0RegionNote=RNA-interacting domain 2
TgeneTERTchr5:272887chr5:1282739ENST00000334602115376_521524.33333333333341070.0RegionNote=QFP motif
TgeneTERTchr5:272887chr5:1282739ENST00000334602115397_417524.33333333333341070.0RegionNote=CP motif
TgeneTERTchr5:272887chr5:1282739ENST0000033460211558_197524.33333333333341070.0RegionNote=GQ motif
TgeneTERTchr5:272887chr5:1282739ENST00000508104181_230524.3333333333334808.0RegionNote=RNA-interacting domain 1
TgeneTERTchr5:272887chr5:1282739ENST0000050810418231_324524.3333333333334808.0RegionNote=Linker
TgeneTERTchr5:272887chr5:1282739ENST0000050810418301_538524.3333333333334808.0RegionNote=Required for oligomerization
TgeneTERTchr5:272887chr5:1282739ENST0000050810418325_550524.3333333333334808.0RegionNote=RNA-interacting domain 2
TgeneTERTchr5:272887chr5:1282739ENST0000050810418376_521524.3333333333334808.0RegionNote=QFP motif
TgeneTERTchr5:272887chr5:1282739ENST0000050810418397_417524.3333333333334808.0RegionNote=CP motif
TgeneTERTchr5:272887chr5:1282739ENST000005081041858_197524.3333333333334808.0RegionNote=GQ motif


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Fusion Gene Sequence for PDCD6-TERT


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000264933_ENST00000310581_TCGA-BP-4991-01A_PDCD6_chr5_272887_+_TERT_chr5_1282739_length(transcript)=2650nt_BP=263nt
GATAATGCCAGGCCCTGCCCCCGGCAGAGGCGGAAGCGGAGTCGGCCTGAGAGGTCTCTCGTCGCTGCAGGCGCCTCAGCCCAGCCGCGT
GCCTTGGCCCATGGCCGCCTACTCTTACCGCCCCGGCCCTGGGGCCGGCCCTGGGCCTGCTGCAGGCGCGGCGCTGCCGGACCAGAGCTT
CCTGTGGAACGTTTTCCAGAGGGTCGATAAAGACAGGAGTGGAGTGATATCAGACACCGAGCTTCAGCAAGCTCTCTCCAACGGGGTTGG
CTGTGTTCCGGCCGCAGAGCACCGTCTGCGTGAGGAGATCCTGGCCAAGTTCCTGCACTGGCTGATGAGTGTGTACGTCGTCGAGCTGCT
CAGGTCTTTCTTTTATGTCACGGAGACCACGTTTCAAAAGAACAGGCTCTTTTTCTACCGGAAGAGTGTCTGGAGCAAGTTGCAAAGCAT
TGGAATCAGACAGCACTTGAAGAGGGTGCAGCTGCGGGAGCTGTCGGAAGCAGAGGTCAGGCAGCATCGGGAAGCCAGGCCCGCCCTGCT
GACGTCCAGACTCCGCTTCATCCCCAAGCCTGACGGGCTGCGGCCGATTGTGAACATGGACTACGTCGTGGGAGCCAGAACGTTCCGCAG
AGAAAAGAGGGCCGAGCGTCTCACCTCGAGGGTGAAGGCACTGTTCAGCGTGCTCAACTACGAGCGGGCGCGGCGCCCCGGCCTCCTGGG
CGCCTCTGTGCTGGGCCTGGACGATATCCACAGGGCCTGGCGCACCTTCGTGCTGCGTGTGCGGGCCCAGGACCCGCCGCCTGAGCTGTA
CTTTGTCAAGGTGGATGTGACGGGCGCGTACGACACCATCCCCCAGGACAGGCTCACGGAGGTCATCGCCAGCATCATCAAACCCCAGAA
CACGTACTGCGTGCGTCGGTATGCCGTGGTCCAGAAGGCCGCCCATGGGCACGTCCGCAAGGCCTTCAAGAGCCACGTCTCTACCTTGAC
AGACCTCCAGCCGTACATGCGACAGTTCGTGGCTCACCTGCAGGAGACCAGCCCGCTGAGGGATGCCGTCGTCATCGAGCAGAGCTCCTC
CCTGAATGAGGCCAGCAGTGGCCTCTTCGACGTCTTCCTACGCTTCATGTGCCACCACGCCGTGCGCATCAGGGGCAAGTCCTACGTCCA
GTGCCAGGGGATCCCGCAGGGCTCCATCCTCTCCACGCTGCTCTGCAGCCTGTGCTACGGCGACATGGAGAACAAGCTGTTTGCGGGGAT
TCGGCGGGACGGGCTGCTCCTGCGTTTGGTGGATGATTTCTTGTTGGTGACACCTCACCTCACCCACGCGAAAACCTTCCTCAGGACCCT
GGTCCGAGGTGTCCCTGAGTATGGCTGCGTGGTGAACTTGCGGAAGACAGTGGTGAACTTCCCTGTAGAAGACGAGGCCCTGGGTGGCAC
GGCTTTTGTTCAGATGCCGGCCCACGGCCTATTCCCCTGGTGCGGCCTGCTGCTGGATACCCGGACCCTGGAGGTGCAGAGCGACTACTC
CAGCTATGCCCGGACCTCCATCAGAGCCAGTCTCACCTTCAACCGCGGCTTCAAGGCTGGGAGGAACATGCGTCGCAAACTCTTTGGGGT
CTTGCGGCTGAAGTGTCACAGCCTGTTTCTGGATTTGCAGGTGAACAGCCTCCAGACGGTGTGCACCAACATCTACAAGATCCTCCTGCT
GCAGGCGTACAGGTTTCACGCATGTGTGCTGCAGCTCCCATTTCATCAGCAAGTTTGGAAGAACCCCACATTTTTCCTGCGCGTCATCTC
TGACACGGCCTCCCTCTGCTACTCCATCCTGAAAGCCAAGAACGCAGGGATGTCGCTGGGGGCCAAGGGCGCCGCCGGCCCTCTGCCCTC
CGAGGCCGTGCAGTGGCTGTGCCACCAAGCATTCCTGCTCAAGCTGACTCGACACCGTGTCACCTACGTGCCACTCCTGGGGTCACTCAG
GACAGCCCAGACGCAGCTGAGTCGGAAGCTCCCGGGGACGACGCTGACTGCCCTGGAGGCCGCAGCCAACCCGGCACTGCCCTCAGACTT
CAAGACCATCCTGGACTGATGGCCACCCGCCCACAGCCAGGCCGAGAGCAGACACCAGCAGCCCTGTCACGCCGGGCTCTACGTCCCAGG
GAGGGAGGGGCGGCCCACACCCAGGCCCGCACCGCTGGGAGTCTGAGGCCTGAGTGAGTGTTTGGCCGAGGCCTGCATGTCCGGCTGAAG
GCTGAGTGTCCGGCTGAGGCCTGAGCGAGTGTCCAGCCAAGGGCTGAGTGTCCAGCACACCTGCCGTCTTCACTTCCCCACAGGCTGGCG
CTCGGCTCCACCCCAGGGCCAGCTTTTCCTCACCAGGAGCCCGGCTTCCACTCCCCACATAGGAATAGTCCATCCCCAGATTCGCCATTG
TTCACCCCTCGCCCTGCCCTCCTTTGCCTTCCACCCCCACCATCCAGGTGGAGACCCTGAGAAGGACCCTGGGAGCTCTGGGAATTTGGA
GTGACCAAAGGTGTGCCCTGTACACAGGCGAGGACCCTGCACCTGGATGGGGGTCCCTGTGGGTCAAATTGGGGGGAGGTGCTGTGGGAG

>In-frame_ENST00000264933_ENST00000310581_TCGA-BP-4991-01A_PDCD6_chr5_272887_+_TERT_chr5_1282739_length(amino acids)=694AA_start in transcript=4_stop in transcript=2088
MPGPAPGRGGSGVGLRGLSSLQAPQPSRVPWPMAAYSYRPGPGAGPGPAAGAALPDQSFLWNVFQRVDKDRSGVISDTELQQALSNGVGC
VPAAEHRLREEILAKFLHWLMSVYVVELLRSFFYVTETTFQKNRLFFYRKSVWSKLQSIGIRQHLKRVQLRELSEAEVRQHREARPALLT
SRLRFIPKPDGLRPIVNMDYVVGARTFRREKRAERLTSRVKALFSVLNYERARRPGLLGASVLGLDDIHRAWRTFVLRVRAQDPPPELYF
VKVDVTGAYDTIPQDRLTEVIASIIKPQNTYCVRRYAVVQKAAHGHVRKAFKSHVSTLTDLQPYMRQFVAHLQETSPLRDAVVIEQSSSL
NEASSGLFDVFLRFMCHHAVRIRGKSYVQCQGIPQGSILSTLLCSLCYGDMENKLFAGIRRDGLLLRLVDDFLLVTPHLTHAKTFLRTLV
RGVPEYGCVVNLRKTVVNFPVEDEALGGTAFVQMPAHGLFPWCGLLLDTRTLEVQSDYSSYARTSIRASLTFNRGFKAGRNMRRKLFGVL
RLKCHSLFLDLQVNSLQTVCTNIYKILLLQAYRFHACVLQLPFHQQVWKNPTFFLRVISDTASLCYSILKAKNAGMSLGAKGAAGPLPSE

--------------------------------------------------------------
>In-frame_ENST00000264933_ENST00000334602_TCGA-BP-4991-01A_PDCD6_chr5_272887_+_TERT_chr5_1282739_length(transcript)=1900nt_BP=263nt
GATAATGCCAGGCCCTGCCCCCGGCAGAGGCGGAAGCGGAGTCGGCCTGAGAGGTCTCTCGTCGCTGCAGGCGCCTCAGCCCAGCCGCGT
GCCTTGGCCCATGGCCGCCTACTCTTACCGCCCCGGCCCTGGGGCCGGCCCTGGGCCTGCTGCAGGCGCGGCGCTGCCGGACCAGAGCTT
CCTGTGGAACGTTTTCCAGAGGGTCGATAAAGACAGGAGTGGAGTGATATCAGACACCGAGCTTCAGCAAGCTCTCTCCAACGGGGTTGG
CTGTGTTCCGGCCGCAGAGCACCGTCTGCGTGAGGAGATCCTGGCCAAGTTCCTGCACTGGCTGATGAGTGTGTACGTCGTCGAGCTGCT
CAGGTCTTTCTTTTATGTCACGGAGACCACGTTTCAAAAGAACAGGCTCTTTTTCTACCGGAAGAGTGTCTGGAGCAAGTTGCAAAGCAT
TGGAATCAGACAGCACTTGAAGAGGGTGCAGCTGCGGGAGCTGTCGGAAGCAGAGGTCAGGCAGCATCGGGAAGCCAGGCCCGCCCTGCT
GACGTCCAGACTCCGCTTCATCCCCAAGCCTGACGGGCTGCGGCCGATTGTGAACATGGACTACGTCGTGGGAGCCAGAACGTTCCGCAG
AGAAAAGAGGGCCGAGCGTCTCACCTCGAGGGTGAAGGCACTGTTCAGCGTGCTCAACTACGAGCGGGCGCGGCGCCCCGGCCTCCTGGG
CGCCTCTGTGCTGGGCCTGGACGATATCCACAGGGCCTGGCGCACCTTCGTGCTGCGTGTGCGGGCCCAGGACCCGCCGCCTGAGCTGTA
CTTTGTCAAGGTGGATGTGACGGGCGCGTACGACACCATCCCCCAGGACAGGCTCACGGAGGTCATCGCCAGCATCATCAAACCCCAGAA
CACGTACTGCGTGCGTCGGTATGCCGTGGTCCAGAAGGCCGCCCATGGGCACGTCCGCAAGGCCTTCAAGAGCCACGTCTCTACCTTGAC
AGACCTCCAGCCGTACATGCGACAGTTCGTGGCTCACCTGCAGGAGACCAGCCCGCTGAGGGATGCCGTCGTCATCGAGCAGAGCTCCTC
CCTGAATGAGGCCAGCAGTGGCCTCTTCGACGTCTTCCTACGCTTCATGTGCCACCACGCCGTGCGCATCAGGGGCAAGTCCTACGTCCA
GTGCCAGGGGATCCCGCAGGGCTCCATCCTCTCCACGCTGCTCTGCAGCCTGTGCTACGGCGACATGGAGAACAAGCTGTTTGCGGGGAT
TCGGCGGGACGGGCTGCTCCTGCGTTTGGTGGATGATTTCTTGTTGGTGACACCTCACCTCACCCACGCGAAAACCTTCCTCAGCTATGC
CCGGACCTCCATCAGAGCCAGTCTCACCTTCAACCGCGGCTTCAAGGCTGGGAGGAACATGCGTCGCAAACTCTTTGGGGTCTTGCGGCT
GAAGTGTCACAGCCTGTTTCTGGATTTGCAGGTGAACAGCCTCCAGACGGTGTGCACCAACATCTACAAGATCCTCCTGCTGCAGGCGTA
CAGGTTTCACGCATGTGTGCTGCAGCTCCCATTTCATCAGCAAGTTTGGAAGAACCCCACATTTTTCCTGCGCGTCATCTCTGACACGGC
CTCCCTCTGCTACTCCATCCTGAAAGCCAAGAACGCAGGGATGTCGCTGGGGGCCAAGGGCGCCGCCGGCCCTCTGCCCTCCGAGGCCGT
GCAGTGGCTGTGCCACCAAGCATTCCTGCTCAAGCTGACTCGACACCGTGTCACCTACGTGCCACTCCTGGGGTCACTCAGGACAGCCCA
GACGCAGCTGAGTCGGAAGCTCCCGGGGACGACGCTGACTGCCCTGGAGGCCGCAGCCAACCCGGCACTGCCCTCAGACTTCAAGACCAT

>In-frame_ENST00000264933_ENST00000334602_TCGA-BP-4991-01A_PDCD6_chr5_272887_+_TERT_chr5_1282739_length(amino acids)=632AA_start in transcript=4_stop in transcript=1899
MPGPAPGRGGSGVGLRGLSSLQAPQPSRVPWPMAAYSYRPGPGAGPGPAAGAALPDQSFLWNVFQRVDKDRSGVISDTELQQALSNGVGC
VPAAEHRLREEILAKFLHWLMSVYVVELLRSFFYVTETTFQKNRLFFYRKSVWSKLQSIGIRQHLKRVQLRELSEAEVRQHREARPALLT
SRLRFIPKPDGLRPIVNMDYVVGARTFRREKRAERLTSRVKALFSVLNYERARRPGLLGASVLGLDDIHRAWRTFVLRVRAQDPPPELYF
VKVDVTGAYDTIPQDRLTEVIASIIKPQNTYCVRRYAVVQKAAHGHVRKAFKSHVSTLTDLQPYMRQFVAHLQETSPLRDAVVIEQSSSL
NEASSGLFDVFLRFMCHHAVRIRGKSYVQCQGIPQGSILSTLLCSLCYGDMENKLFAGIRRDGLLLRLVDDFLLVTPHLTHAKTFLSYAR
TSIRASLTFNRGFKAGRNMRRKLFGVLRLKCHSLFLDLQVNSLQTVCTNIYKILLLQAYRFHACVLQLPFHQQVWKNPTFFLRVISDTAS
LCYSILKAKNAGMSLGAKGAAGPLPSEAVQWLCHQAFLLKLTRHRVTYVPLLGSLRTAQTQLSRKLPGTTLTALEAAANPALPSDFKTIL

--------------------------------------------------------------
>In-frame_ENST00000264933_ENST00000508104_TCGA-BP-4991-01A_PDCD6_chr5_272887_+_TERT_chr5_1282739_length(transcript)=1176nt_BP=263nt
GATAATGCCAGGCCCTGCCCCCGGCAGAGGCGGAAGCGGAGTCGGCCTGAGAGGTCTCTCGTCGCTGCAGGCGCCTCAGCCCAGCCGCGT
GCCTTGGCCCATGGCCGCCTACTCTTACCGCCCCGGCCCTGGGGCCGGCCCTGGGCCTGCTGCAGGCGCGGCGCTGCCGGACCAGAGCTT
CCTGTGGAACGTTTTCCAGAGGGTCGATAAAGACAGGAGTGGAGTGATATCAGACACCGAGCTTCAGCAAGCTCTCTCCAACGGGGTTGG
CTGTGTTCCGGCCGCAGAGCACCGTCTGCGTGAGGAGATCCTGGCCAAGTTCCTGCACTGGCTGATGAGTGTGTACGTCGTCGAGCTGCT
CAGGTCTTTCTTTTATGTCACGGAGACCACGTTTCAAAAGAACAGGCTCTTTTTCTACCGGAAGAGTGTCTGGAGCAAGTTGCAAAGCAT
TGGAATCAGACAGCACTTGAAGAGGGTGCAGCTGCGGGAGCTGTCGGAAGCAGAGGTCAGGCAGCATCGGGAAGCCAGGCCCGCCCTGCT
GACGTCCAGACTCCGCTTCATCCCCAAGCCTGACGGGCTGCGGCCGATTGTGAACATGGACTACGTCGTGGGAGCCAGAACGTTCCGCAG
AGAAAAGAGGGCCGAGCGTCTCACCTCGAGGGTGAAGGCACTGTTCAGCGTGCTCAACTACGAGCGGGCGCGGCGCCCCGGCCTCCTGGG
CGCCTCTGTGCTGGGCCTGGACGATATCCACAGGGCCTGGCGCACCTTCGTGCTGCGTGTGCGGGCCCAGGACCCGCCGCCTGAGCTGTA
CTTTGTCAAGGTGGATGTGACGGGCGCGTACGACACCATCCCCCAGGACAGGCTCACGGAGGTCATCGCCAGCATCATCAAACCCCAGAA
CACGTACTGCGTGCGTCGGTATGCCGTGGTCCAGAAGGCCGCCCATGGGCACGTCCGCAAGGCCTTCAAGAGCCACGTCCTACGTCCAGT
GCCAGGGGATCCCGCAGGGCTCCATCCTCTCCACGCTGCTCTGCAGCCTGTGCTACGGCGACATGGAGAACAAGCTGTTTGCGGGGATTC
GGCGGGACGGGCTGCTCCTGCGTTTGGTGGATGATTTCTTGTTGGTGACACCTCACCTCACCCACGCGAAAACCTTCCTCAGGTGAGGCC

>In-frame_ENST00000264933_ENST00000508104_TCGA-BP-4991-01A_PDCD6_chr5_272887_+_TERT_chr5_1282739_length(amino acids)=369AA_start in transcript=4_stop in transcript=1113
MPGPAPGRGGSGVGLRGLSSLQAPQPSRVPWPMAAYSYRPGPGAGPGPAAGAALPDQSFLWNVFQRVDKDRSGVISDTELQQALSNGVGC
VPAAEHRLREEILAKFLHWLMSVYVVELLRSFFYVTETTFQKNRLFFYRKSVWSKLQSIGIRQHLKRVQLRELSEAEVRQHREARPALLT
SRLRFIPKPDGLRPIVNMDYVVGARTFRREKRAERLTSRVKALFSVLNYERARRPGLLGASVLGLDDIHRAWRTFVLRVRAQDPPPELYF
VKVDVTGAYDTIPQDRLTEVIASIIKPQNTYCVRRYAVVQKAAHGHVRKAFKSHVLRPVPGDPAGLHPLHAALQPVLRRHGEQAVCGDSA

--------------------------------------------------------------
>In-frame_ENST00000505221_ENST00000310581_TCGA-BP-4991-01A_PDCD6_chr5_272887_+_TERT_chr5_1282739_length(transcript)=2624nt_BP=237nt
GAGGCGGAAGCGGAGTCGGCCTGAGAGGTCTCTCGTCGCTGCAGGCGCCTCAGCCCAGCCGCGTGCCTTGGCCCATGGCCGCCTACTCTT
ACCGCCCCGGCCCTGGGGCCGGCCCTGGGCCTGCTGCAGGCGCGGCGCTGCCGGACCAGAGCTTCCTGTGGAACGTTTTCCAGAGGGTCG
ATAAAGACAGGAGTGGAGTGATATCAGACACCGAGCTTCAGCAAGCTCTCTCCAACGGGGTTGGCTGTGTTCCGGCCGCAGAGCACCGTC
TGCGTGAGGAGATCCTGGCCAAGTTCCTGCACTGGCTGATGAGTGTGTACGTCGTCGAGCTGCTCAGGTCTTTCTTTTATGTCACGGAGA
CCACGTTTCAAAAGAACAGGCTCTTTTTCTACCGGAAGAGTGTCTGGAGCAAGTTGCAAAGCATTGGAATCAGACAGCACTTGAAGAGGG
TGCAGCTGCGGGAGCTGTCGGAAGCAGAGGTCAGGCAGCATCGGGAAGCCAGGCCCGCCCTGCTGACGTCCAGACTCCGCTTCATCCCCA
AGCCTGACGGGCTGCGGCCGATTGTGAACATGGACTACGTCGTGGGAGCCAGAACGTTCCGCAGAGAAAAGAGGGCCGAGCGTCTCACCT
CGAGGGTGAAGGCACTGTTCAGCGTGCTCAACTACGAGCGGGCGCGGCGCCCCGGCCTCCTGGGCGCCTCTGTGCTGGGCCTGGACGATA
TCCACAGGGCCTGGCGCACCTTCGTGCTGCGTGTGCGGGCCCAGGACCCGCCGCCTGAGCTGTACTTTGTCAAGGTGGATGTGACGGGCG
CGTACGACACCATCCCCCAGGACAGGCTCACGGAGGTCATCGCCAGCATCATCAAACCCCAGAACACGTACTGCGTGCGTCGGTATGCCG
TGGTCCAGAAGGCCGCCCATGGGCACGTCCGCAAGGCCTTCAAGAGCCACGTCTCTACCTTGACAGACCTCCAGCCGTACATGCGACAGT
TCGTGGCTCACCTGCAGGAGACCAGCCCGCTGAGGGATGCCGTCGTCATCGAGCAGAGCTCCTCCCTGAATGAGGCCAGCAGTGGCCTCT
TCGACGTCTTCCTACGCTTCATGTGCCACCACGCCGTGCGCATCAGGGGCAAGTCCTACGTCCAGTGCCAGGGGATCCCGCAGGGCTCCA
TCCTCTCCACGCTGCTCTGCAGCCTGTGCTACGGCGACATGGAGAACAAGCTGTTTGCGGGGATTCGGCGGGACGGGCTGCTCCTGCGTT
TGGTGGATGATTTCTTGTTGGTGACACCTCACCTCACCCACGCGAAAACCTTCCTCAGGACCCTGGTCCGAGGTGTCCCTGAGTATGGCT
GCGTGGTGAACTTGCGGAAGACAGTGGTGAACTTCCCTGTAGAAGACGAGGCCCTGGGTGGCACGGCTTTTGTTCAGATGCCGGCCCACG
GCCTATTCCCCTGGTGCGGCCTGCTGCTGGATACCCGGACCCTGGAGGTGCAGAGCGACTACTCCAGCTATGCCCGGACCTCCATCAGAG
CCAGTCTCACCTTCAACCGCGGCTTCAAGGCTGGGAGGAACATGCGTCGCAAACTCTTTGGGGTCTTGCGGCTGAAGTGTCACAGCCTGT
TTCTGGATTTGCAGGTGAACAGCCTCCAGACGGTGTGCACCAACATCTACAAGATCCTCCTGCTGCAGGCGTACAGGTTTCACGCATGTG
TGCTGCAGCTCCCATTTCATCAGCAAGTTTGGAAGAACCCCACATTTTTCCTGCGCGTCATCTCTGACACGGCCTCCCTCTGCTACTCCA
TCCTGAAAGCCAAGAACGCAGGGATGTCGCTGGGGGCCAAGGGCGCCGCCGGCCCTCTGCCCTCCGAGGCCGTGCAGTGGCTGTGCCACC
AAGCATTCCTGCTCAAGCTGACTCGACACCGTGTCACCTACGTGCCACTCCTGGGGTCACTCAGGACAGCCCAGACGCAGCTGAGTCGGA
AGCTCCCGGGGACGACGCTGACTGCCCTGGAGGCCGCAGCCAACCCGGCACTGCCCTCAGACTTCAAGACCATCCTGGACTGATGGCCAC
CCGCCCACAGCCAGGCCGAGAGCAGACACCAGCAGCCCTGTCACGCCGGGCTCTACGTCCCAGGGAGGGAGGGGCGGCCCACACCCAGGC
CCGCACCGCTGGGAGTCTGAGGCCTGAGTGAGTGTTTGGCCGAGGCCTGCATGTCCGGCTGAAGGCTGAGTGTCCGGCTGAGGCCTGAGC
GAGTGTCCAGCCAAGGGCTGAGTGTCCAGCACACCTGCCGTCTTCACTTCCCCACAGGCTGGCGCTCGGCTCCACCCCAGGGCCAGCTTT
TCCTCACCAGGAGCCCGGCTTCCACTCCCCACATAGGAATAGTCCATCCCCAGATTCGCCATTGTTCACCCCTCGCCCTGCCCTCCTTTG
CCTTCCACCCCCACCATCCAGGTGGAGACCCTGAGAAGGACCCTGGGAGCTCTGGGAATTTGGAGTGACCAAAGGTGTGCCCTGTACACA
GGCGAGGACCCTGCACCTGGATGGGGGTCCCTGTGGGTCAAATTGGGGGGAGGTGCTGTGGGAGTAAAATACTGAATATATGAGTTTTTC

>In-frame_ENST00000505221_ENST00000310581_TCGA-BP-4991-01A_PDCD6_chr5_272887_+_TERT_chr5_1282739_length(amino acids)=680AA_start in transcript=20_stop in transcript=2062
MRGLSSLQAPQPSRVPWPMAAYSYRPGPGAGPGPAAGAALPDQSFLWNVFQRVDKDRSGVISDTELQQALSNGVGCVPAAEHRLREEILA
KFLHWLMSVYVVELLRSFFYVTETTFQKNRLFFYRKSVWSKLQSIGIRQHLKRVQLRELSEAEVRQHREARPALLTSRLRFIPKPDGLRP
IVNMDYVVGARTFRREKRAERLTSRVKALFSVLNYERARRPGLLGASVLGLDDIHRAWRTFVLRVRAQDPPPELYFVKVDVTGAYDTIPQ
DRLTEVIASIIKPQNTYCVRRYAVVQKAAHGHVRKAFKSHVSTLTDLQPYMRQFVAHLQETSPLRDAVVIEQSSSLNEASSGLFDVFLRF
MCHHAVRIRGKSYVQCQGIPQGSILSTLLCSLCYGDMENKLFAGIRRDGLLLRLVDDFLLVTPHLTHAKTFLRTLVRGVPEYGCVVNLRK
TVVNFPVEDEALGGTAFVQMPAHGLFPWCGLLLDTRTLEVQSDYSSYARTSIRASLTFNRGFKAGRNMRRKLFGVLRLKCHSLFLDLQVN
SLQTVCTNIYKILLLQAYRFHACVLQLPFHQQVWKNPTFFLRVISDTASLCYSILKAKNAGMSLGAKGAAGPLPSEAVQWLCHQAFLLKL

--------------------------------------------------------------
>In-frame_ENST00000505221_ENST00000334602_TCGA-BP-4991-01A_PDCD6_chr5_272887_+_TERT_chr5_1282739_length(transcript)=1874nt_BP=237nt
GAGGCGGAAGCGGAGTCGGCCTGAGAGGTCTCTCGTCGCTGCAGGCGCCTCAGCCCAGCCGCGTGCCTTGGCCCATGGCCGCCTACTCTT
ACCGCCCCGGCCCTGGGGCCGGCCCTGGGCCTGCTGCAGGCGCGGCGCTGCCGGACCAGAGCTTCCTGTGGAACGTTTTCCAGAGGGTCG
ATAAAGACAGGAGTGGAGTGATATCAGACACCGAGCTTCAGCAAGCTCTCTCCAACGGGGTTGGCTGTGTTCCGGCCGCAGAGCACCGTC
TGCGTGAGGAGATCCTGGCCAAGTTCCTGCACTGGCTGATGAGTGTGTACGTCGTCGAGCTGCTCAGGTCTTTCTTTTATGTCACGGAGA
CCACGTTTCAAAAGAACAGGCTCTTTTTCTACCGGAAGAGTGTCTGGAGCAAGTTGCAAAGCATTGGAATCAGACAGCACTTGAAGAGGG
TGCAGCTGCGGGAGCTGTCGGAAGCAGAGGTCAGGCAGCATCGGGAAGCCAGGCCCGCCCTGCTGACGTCCAGACTCCGCTTCATCCCCA
AGCCTGACGGGCTGCGGCCGATTGTGAACATGGACTACGTCGTGGGAGCCAGAACGTTCCGCAGAGAAAAGAGGGCCGAGCGTCTCACCT
CGAGGGTGAAGGCACTGTTCAGCGTGCTCAACTACGAGCGGGCGCGGCGCCCCGGCCTCCTGGGCGCCTCTGTGCTGGGCCTGGACGATA
TCCACAGGGCCTGGCGCACCTTCGTGCTGCGTGTGCGGGCCCAGGACCCGCCGCCTGAGCTGTACTTTGTCAAGGTGGATGTGACGGGCG
CGTACGACACCATCCCCCAGGACAGGCTCACGGAGGTCATCGCCAGCATCATCAAACCCCAGAACACGTACTGCGTGCGTCGGTATGCCG
TGGTCCAGAAGGCCGCCCATGGGCACGTCCGCAAGGCCTTCAAGAGCCACGTCTCTACCTTGACAGACCTCCAGCCGTACATGCGACAGT
TCGTGGCTCACCTGCAGGAGACCAGCCCGCTGAGGGATGCCGTCGTCATCGAGCAGAGCTCCTCCCTGAATGAGGCCAGCAGTGGCCTCT
TCGACGTCTTCCTACGCTTCATGTGCCACCACGCCGTGCGCATCAGGGGCAAGTCCTACGTCCAGTGCCAGGGGATCCCGCAGGGCTCCA
TCCTCTCCACGCTGCTCTGCAGCCTGTGCTACGGCGACATGGAGAACAAGCTGTTTGCGGGGATTCGGCGGGACGGGCTGCTCCTGCGTT
TGGTGGATGATTTCTTGTTGGTGACACCTCACCTCACCCACGCGAAAACCTTCCTCAGCTATGCCCGGACCTCCATCAGAGCCAGTCTCA
CCTTCAACCGCGGCTTCAAGGCTGGGAGGAACATGCGTCGCAAACTCTTTGGGGTCTTGCGGCTGAAGTGTCACAGCCTGTTTCTGGATT
TGCAGGTGAACAGCCTCCAGACGGTGTGCACCAACATCTACAAGATCCTCCTGCTGCAGGCGTACAGGTTTCACGCATGTGTGCTGCAGC
TCCCATTTCATCAGCAAGTTTGGAAGAACCCCACATTTTTCCTGCGCGTCATCTCTGACACGGCCTCCCTCTGCTACTCCATCCTGAAAG
CCAAGAACGCAGGGATGTCGCTGGGGGCCAAGGGCGCCGCCGGCCCTCTGCCCTCCGAGGCCGTGCAGTGGCTGTGCCACCAAGCATTCC
TGCTCAAGCTGACTCGACACCGTGTCACCTACGTGCCACTCCTGGGGTCACTCAGGACAGCCCAGACGCAGCTGAGTCGGAAGCTCCCGG

>In-frame_ENST00000505221_ENST00000334602_TCGA-BP-4991-01A_PDCD6_chr5_272887_+_TERT_chr5_1282739_length(amino acids)=618AA_start in transcript=20_stop in transcript=1873
MRGLSSLQAPQPSRVPWPMAAYSYRPGPGAGPGPAAGAALPDQSFLWNVFQRVDKDRSGVISDTELQQALSNGVGCVPAAEHRLREEILA
KFLHWLMSVYVVELLRSFFYVTETTFQKNRLFFYRKSVWSKLQSIGIRQHLKRVQLRELSEAEVRQHREARPALLTSRLRFIPKPDGLRP
IVNMDYVVGARTFRREKRAERLTSRVKALFSVLNYERARRPGLLGASVLGLDDIHRAWRTFVLRVRAQDPPPELYFVKVDVTGAYDTIPQ
DRLTEVIASIIKPQNTYCVRRYAVVQKAAHGHVRKAFKSHVSTLTDLQPYMRQFVAHLQETSPLRDAVVIEQSSSLNEASSGLFDVFLRF
MCHHAVRIRGKSYVQCQGIPQGSILSTLLCSLCYGDMENKLFAGIRRDGLLLRLVDDFLLVTPHLTHAKTFLSYARTSIRASLTFNRGFK
AGRNMRRKLFGVLRLKCHSLFLDLQVNSLQTVCTNIYKILLLQAYRFHACVLQLPFHQQVWKNPTFFLRVISDTASLCYSILKAKNAGMS

--------------------------------------------------------------
>In-frame_ENST00000505221_ENST00000508104_TCGA-BP-4991-01A_PDCD6_chr5_272887_+_TERT_chr5_1282739_length(transcript)=1150nt_BP=237nt
GAGGCGGAAGCGGAGTCGGCCTGAGAGGTCTCTCGTCGCTGCAGGCGCCTCAGCCCAGCCGCGTGCCTTGGCCCATGGCCGCCTACTCTT
ACCGCCCCGGCCCTGGGGCCGGCCCTGGGCCTGCTGCAGGCGCGGCGCTGCCGGACCAGAGCTTCCTGTGGAACGTTTTCCAGAGGGTCG
ATAAAGACAGGAGTGGAGTGATATCAGACACCGAGCTTCAGCAAGCTCTCTCCAACGGGGTTGGCTGTGTTCCGGCCGCAGAGCACCGTC
TGCGTGAGGAGATCCTGGCCAAGTTCCTGCACTGGCTGATGAGTGTGTACGTCGTCGAGCTGCTCAGGTCTTTCTTTTATGTCACGGAGA
CCACGTTTCAAAAGAACAGGCTCTTTTTCTACCGGAAGAGTGTCTGGAGCAAGTTGCAAAGCATTGGAATCAGACAGCACTTGAAGAGGG
TGCAGCTGCGGGAGCTGTCGGAAGCAGAGGTCAGGCAGCATCGGGAAGCCAGGCCCGCCCTGCTGACGTCCAGACTCCGCTTCATCCCCA
AGCCTGACGGGCTGCGGCCGATTGTGAACATGGACTACGTCGTGGGAGCCAGAACGTTCCGCAGAGAAAAGAGGGCCGAGCGTCTCACCT
CGAGGGTGAAGGCACTGTTCAGCGTGCTCAACTACGAGCGGGCGCGGCGCCCCGGCCTCCTGGGCGCCTCTGTGCTGGGCCTGGACGATA
TCCACAGGGCCTGGCGCACCTTCGTGCTGCGTGTGCGGGCCCAGGACCCGCCGCCTGAGCTGTACTTTGTCAAGGTGGATGTGACGGGCG
CGTACGACACCATCCCCCAGGACAGGCTCACGGAGGTCATCGCCAGCATCATCAAACCCCAGAACACGTACTGCGTGCGTCGGTATGCCG
TGGTCCAGAAGGCCGCCCATGGGCACGTCCGCAAGGCCTTCAAGAGCCACGTCCTACGTCCAGTGCCAGGGGATCCCGCAGGGCTCCATC
CTCTCCACGCTGCTCTGCAGCCTGTGCTACGGCGACATGGAGAACAAGCTGTTTGCGGGGATTCGGCGGGACGGGCTGCTCCTGCGTTTG

>In-frame_ENST00000505221_ENST00000508104_TCGA-BP-4991-01A_PDCD6_chr5_272887_+_TERT_chr5_1282739_length(amino acids)=355AA_start in transcript=20_stop in transcript=1087
MRGLSSLQAPQPSRVPWPMAAYSYRPGPGAGPGPAAGAALPDQSFLWNVFQRVDKDRSGVISDTELQQALSNGVGCVPAAEHRLREEILA
KFLHWLMSVYVVELLRSFFYVTETTFQKNRLFFYRKSVWSKLQSIGIRQHLKRVQLRELSEAEVRQHREARPALLTSRLRFIPKPDGLRP
IVNMDYVVGARTFRREKRAERLTSRVKALFSVLNYERARRPGLLGASVLGLDDIHRAWRTFVLRVRAQDPPPELYFVKVDVTGAYDTIPQ

--------------------------------------------------------------
>In-frame_ENST00000509581_ENST00000310581_TCGA-BP-4991-01A_PDCD6_chr5_272887_+_TERT_chr5_1282739_length(transcript)=2614nt_BP=227nt
CGGAGTCGGCCTGAGAGGTCTCTCGTCGCTGCAGGCGCCTCAGCCCAGCCGCGTGCCTTGGCCCATGGCCGCCTACTCTTACCGCCCCGG
CCCTGGGGCCGGCCCTGGGCCTGCTGCAGGCGCGGCGCTGCCGGACCAGAGCTTCCTGTGGAACGTTTTCCAGAGGGTCGATAAAGACAG
GAGTGGAGTGATATCAGACACCGAGCTTCAGCAAGCTCTCTCCAACGGGGTTGGCTGTGTTCCGGCCGCAGAGCACCGTCTGCGTGAGGA
GATCCTGGCCAAGTTCCTGCACTGGCTGATGAGTGTGTACGTCGTCGAGCTGCTCAGGTCTTTCTTTTATGTCACGGAGACCACGTTTCA
AAAGAACAGGCTCTTTTTCTACCGGAAGAGTGTCTGGAGCAAGTTGCAAAGCATTGGAATCAGACAGCACTTGAAGAGGGTGCAGCTGCG
GGAGCTGTCGGAAGCAGAGGTCAGGCAGCATCGGGAAGCCAGGCCCGCCCTGCTGACGTCCAGACTCCGCTTCATCCCCAAGCCTGACGG
GCTGCGGCCGATTGTGAACATGGACTACGTCGTGGGAGCCAGAACGTTCCGCAGAGAAAAGAGGGCCGAGCGTCTCACCTCGAGGGTGAA
GGCACTGTTCAGCGTGCTCAACTACGAGCGGGCGCGGCGCCCCGGCCTCCTGGGCGCCTCTGTGCTGGGCCTGGACGATATCCACAGGGC
CTGGCGCACCTTCGTGCTGCGTGTGCGGGCCCAGGACCCGCCGCCTGAGCTGTACTTTGTCAAGGTGGATGTGACGGGCGCGTACGACAC
CATCCCCCAGGACAGGCTCACGGAGGTCATCGCCAGCATCATCAAACCCCAGAACACGTACTGCGTGCGTCGGTATGCCGTGGTCCAGAA
GGCCGCCCATGGGCACGTCCGCAAGGCCTTCAAGAGCCACGTCTCTACCTTGACAGACCTCCAGCCGTACATGCGACAGTTCGTGGCTCA
CCTGCAGGAGACCAGCCCGCTGAGGGATGCCGTCGTCATCGAGCAGAGCTCCTCCCTGAATGAGGCCAGCAGTGGCCTCTTCGACGTCTT
CCTACGCTTCATGTGCCACCACGCCGTGCGCATCAGGGGCAAGTCCTACGTCCAGTGCCAGGGGATCCCGCAGGGCTCCATCCTCTCCAC
GCTGCTCTGCAGCCTGTGCTACGGCGACATGGAGAACAAGCTGTTTGCGGGGATTCGGCGGGACGGGCTGCTCCTGCGTTTGGTGGATGA
TTTCTTGTTGGTGACACCTCACCTCACCCACGCGAAAACCTTCCTCAGGACCCTGGTCCGAGGTGTCCCTGAGTATGGCTGCGTGGTGAA
CTTGCGGAAGACAGTGGTGAACTTCCCTGTAGAAGACGAGGCCCTGGGTGGCACGGCTTTTGTTCAGATGCCGGCCCACGGCCTATTCCC
CTGGTGCGGCCTGCTGCTGGATACCCGGACCCTGGAGGTGCAGAGCGACTACTCCAGCTATGCCCGGACCTCCATCAGAGCCAGTCTCAC
CTTCAACCGCGGCTTCAAGGCTGGGAGGAACATGCGTCGCAAACTCTTTGGGGTCTTGCGGCTGAAGTGTCACAGCCTGTTTCTGGATTT
GCAGGTGAACAGCCTCCAGACGGTGTGCACCAACATCTACAAGATCCTCCTGCTGCAGGCGTACAGGTTTCACGCATGTGTGCTGCAGCT
CCCATTTCATCAGCAAGTTTGGAAGAACCCCACATTTTTCCTGCGCGTCATCTCTGACACGGCCTCCCTCTGCTACTCCATCCTGAAAGC
CAAGAACGCAGGGATGTCGCTGGGGGCCAAGGGCGCCGCCGGCCCTCTGCCCTCCGAGGCCGTGCAGTGGCTGTGCCACCAAGCATTCCT
GCTCAAGCTGACTCGACACCGTGTCACCTACGTGCCACTCCTGGGGTCACTCAGGACAGCCCAGACGCAGCTGAGTCGGAAGCTCCCGGG
GACGACGCTGACTGCCCTGGAGGCCGCAGCCAACCCGGCACTGCCCTCAGACTTCAAGACCATCCTGGACTGATGGCCACCCGCCCACAG
CCAGGCCGAGAGCAGACACCAGCAGCCCTGTCACGCCGGGCTCTACGTCCCAGGGAGGGAGGGGCGGCCCACACCCAGGCCCGCACCGCT
GGGAGTCTGAGGCCTGAGTGAGTGTTTGGCCGAGGCCTGCATGTCCGGCTGAAGGCTGAGTGTCCGGCTGAGGCCTGAGCGAGTGTCCAG
CCAAGGGCTGAGTGTCCAGCACACCTGCCGTCTTCACTTCCCCACAGGCTGGCGCTCGGCTCCACCCCAGGGCCAGCTTTTCCTCACCAG
GAGCCCGGCTTCCACTCCCCACATAGGAATAGTCCATCCCCAGATTCGCCATTGTTCACCCCTCGCCCTGCCCTCCTTTGCCTTCCACCC
CCACCATCCAGGTGGAGACCCTGAGAAGGACCCTGGGAGCTCTGGGAATTTGGAGTGACCAAAGGTGTGCCCTGTACACAGGCGAGGACC
CTGCACCTGGATGGGGGTCCCTGTGGGTCAAATTGGGGGGAGGTGCTGTGGGAGTAAAATACTGAATATATGAGTTTTTCAGTTTTGAAA

>In-frame_ENST00000509581_ENST00000310581_TCGA-BP-4991-01A_PDCD6_chr5_272887_+_TERT_chr5_1282739_length(amino acids)=680AA_start in transcript=10_stop in transcript=2052
MRGLSSLQAPQPSRVPWPMAAYSYRPGPGAGPGPAAGAALPDQSFLWNVFQRVDKDRSGVISDTELQQALSNGVGCVPAAEHRLREEILA
KFLHWLMSVYVVELLRSFFYVTETTFQKNRLFFYRKSVWSKLQSIGIRQHLKRVQLRELSEAEVRQHREARPALLTSRLRFIPKPDGLRP
IVNMDYVVGARTFRREKRAERLTSRVKALFSVLNYERARRPGLLGASVLGLDDIHRAWRTFVLRVRAQDPPPELYFVKVDVTGAYDTIPQ
DRLTEVIASIIKPQNTYCVRRYAVVQKAAHGHVRKAFKSHVSTLTDLQPYMRQFVAHLQETSPLRDAVVIEQSSSLNEASSGLFDVFLRF
MCHHAVRIRGKSYVQCQGIPQGSILSTLLCSLCYGDMENKLFAGIRRDGLLLRLVDDFLLVTPHLTHAKTFLRTLVRGVPEYGCVVNLRK
TVVNFPVEDEALGGTAFVQMPAHGLFPWCGLLLDTRTLEVQSDYSSYARTSIRASLTFNRGFKAGRNMRRKLFGVLRLKCHSLFLDLQVN
SLQTVCTNIYKILLLQAYRFHACVLQLPFHQQVWKNPTFFLRVISDTASLCYSILKAKNAGMSLGAKGAAGPLPSEAVQWLCHQAFLLKL

--------------------------------------------------------------
>In-frame_ENST00000509581_ENST00000334602_TCGA-BP-4991-01A_PDCD6_chr5_272887_+_TERT_chr5_1282739_length(transcript)=1864nt_BP=227nt
CGGAGTCGGCCTGAGAGGTCTCTCGTCGCTGCAGGCGCCTCAGCCCAGCCGCGTGCCTTGGCCCATGGCCGCCTACTCTTACCGCCCCGG
CCCTGGGGCCGGCCCTGGGCCTGCTGCAGGCGCGGCGCTGCCGGACCAGAGCTTCCTGTGGAACGTTTTCCAGAGGGTCGATAAAGACAG
GAGTGGAGTGATATCAGACACCGAGCTTCAGCAAGCTCTCTCCAACGGGGTTGGCTGTGTTCCGGCCGCAGAGCACCGTCTGCGTGAGGA
GATCCTGGCCAAGTTCCTGCACTGGCTGATGAGTGTGTACGTCGTCGAGCTGCTCAGGTCTTTCTTTTATGTCACGGAGACCACGTTTCA
AAAGAACAGGCTCTTTTTCTACCGGAAGAGTGTCTGGAGCAAGTTGCAAAGCATTGGAATCAGACAGCACTTGAAGAGGGTGCAGCTGCG
GGAGCTGTCGGAAGCAGAGGTCAGGCAGCATCGGGAAGCCAGGCCCGCCCTGCTGACGTCCAGACTCCGCTTCATCCCCAAGCCTGACGG
GCTGCGGCCGATTGTGAACATGGACTACGTCGTGGGAGCCAGAACGTTCCGCAGAGAAAAGAGGGCCGAGCGTCTCACCTCGAGGGTGAA
GGCACTGTTCAGCGTGCTCAACTACGAGCGGGCGCGGCGCCCCGGCCTCCTGGGCGCCTCTGTGCTGGGCCTGGACGATATCCACAGGGC
CTGGCGCACCTTCGTGCTGCGTGTGCGGGCCCAGGACCCGCCGCCTGAGCTGTACTTTGTCAAGGTGGATGTGACGGGCGCGTACGACAC
CATCCCCCAGGACAGGCTCACGGAGGTCATCGCCAGCATCATCAAACCCCAGAACACGTACTGCGTGCGTCGGTATGCCGTGGTCCAGAA
GGCCGCCCATGGGCACGTCCGCAAGGCCTTCAAGAGCCACGTCTCTACCTTGACAGACCTCCAGCCGTACATGCGACAGTTCGTGGCTCA
CCTGCAGGAGACCAGCCCGCTGAGGGATGCCGTCGTCATCGAGCAGAGCTCCTCCCTGAATGAGGCCAGCAGTGGCCTCTTCGACGTCTT
CCTACGCTTCATGTGCCACCACGCCGTGCGCATCAGGGGCAAGTCCTACGTCCAGTGCCAGGGGATCCCGCAGGGCTCCATCCTCTCCAC
GCTGCTCTGCAGCCTGTGCTACGGCGACATGGAGAACAAGCTGTTTGCGGGGATTCGGCGGGACGGGCTGCTCCTGCGTTTGGTGGATGA
TTTCTTGTTGGTGACACCTCACCTCACCCACGCGAAAACCTTCCTCAGCTATGCCCGGACCTCCATCAGAGCCAGTCTCACCTTCAACCG
CGGCTTCAAGGCTGGGAGGAACATGCGTCGCAAACTCTTTGGGGTCTTGCGGCTGAAGTGTCACAGCCTGTTTCTGGATTTGCAGGTGAA
CAGCCTCCAGACGGTGTGCACCAACATCTACAAGATCCTCCTGCTGCAGGCGTACAGGTTTCACGCATGTGTGCTGCAGCTCCCATTTCA
TCAGCAAGTTTGGAAGAACCCCACATTTTTCCTGCGCGTCATCTCTGACACGGCCTCCCTCTGCTACTCCATCCTGAAAGCCAAGAACGC
AGGGATGTCGCTGGGGGCCAAGGGCGCCGCCGGCCCTCTGCCCTCCGAGGCCGTGCAGTGGCTGTGCCACCAAGCATTCCTGCTCAAGCT
GACTCGACACCGTGTCACCTACGTGCCACTCCTGGGGTCACTCAGGACAGCCCAGACGCAGCTGAGTCGGAAGCTCCCGGGGACGACGCT

>In-frame_ENST00000509581_ENST00000334602_TCGA-BP-4991-01A_PDCD6_chr5_272887_+_TERT_chr5_1282739_length(amino acids)=618AA_start in transcript=10_stop in transcript=1863
MRGLSSLQAPQPSRVPWPMAAYSYRPGPGAGPGPAAGAALPDQSFLWNVFQRVDKDRSGVISDTELQQALSNGVGCVPAAEHRLREEILA
KFLHWLMSVYVVELLRSFFYVTETTFQKNRLFFYRKSVWSKLQSIGIRQHLKRVQLRELSEAEVRQHREARPALLTSRLRFIPKPDGLRP
IVNMDYVVGARTFRREKRAERLTSRVKALFSVLNYERARRPGLLGASVLGLDDIHRAWRTFVLRVRAQDPPPELYFVKVDVTGAYDTIPQ
DRLTEVIASIIKPQNTYCVRRYAVVQKAAHGHVRKAFKSHVSTLTDLQPYMRQFVAHLQETSPLRDAVVIEQSSSLNEASSGLFDVFLRF
MCHHAVRIRGKSYVQCQGIPQGSILSTLLCSLCYGDMENKLFAGIRRDGLLLRLVDDFLLVTPHLTHAKTFLSYARTSIRASLTFNRGFK
AGRNMRRKLFGVLRLKCHSLFLDLQVNSLQTVCTNIYKILLLQAYRFHACVLQLPFHQQVWKNPTFFLRVISDTASLCYSILKAKNAGMS

--------------------------------------------------------------
>In-frame_ENST00000509581_ENST00000508104_TCGA-BP-4991-01A_PDCD6_chr5_272887_+_TERT_chr5_1282739_length(transcript)=1140nt_BP=227nt
CGGAGTCGGCCTGAGAGGTCTCTCGTCGCTGCAGGCGCCTCAGCCCAGCCGCGTGCCTTGGCCCATGGCCGCCTACTCTTACCGCCCCGG
CCCTGGGGCCGGCCCTGGGCCTGCTGCAGGCGCGGCGCTGCCGGACCAGAGCTTCCTGTGGAACGTTTTCCAGAGGGTCGATAAAGACAG
GAGTGGAGTGATATCAGACACCGAGCTTCAGCAAGCTCTCTCCAACGGGGTTGGCTGTGTTCCGGCCGCAGAGCACCGTCTGCGTGAGGA
GATCCTGGCCAAGTTCCTGCACTGGCTGATGAGTGTGTACGTCGTCGAGCTGCTCAGGTCTTTCTTTTATGTCACGGAGACCACGTTTCA
AAAGAACAGGCTCTTTTTCTACCGGAAGAGTGTCTGGAGCAAGTTGCAAAGCATTGGAATCAGACAGCACTTGAAGAGGGTGCAGCTGCG
GGAGCTGTCGGAAGCAGAGGTCAGGCAGCATCGGGAAGCCAGGCCCGCCCTGCTGACGTCCAGACTCCGCTTCATCCCCAAGCCTGACGG
GCTGCGGCCGATTGTGAACATGGACTACGTCGTGGGAGCCAGAACGTTCCGCAGAGAAAAGAGGGCCGAGCGTCTCACCTCGAGGGTGAA
GGCACTGTTCAGCGTGCTCAACTACGAGCGGGCGCGGCGCCCCGGCCTCCTGGGCGCCTCTGTGCTGGGCCTGGACGATATCCACAGGGC
CTGGCGCACCTTCGTGCTGCGTGTGCGGGCCCAGGACCCGCCGCCTGAGCTGTACTTTGTCAAGGTGGATGTGACGGGCGCGTACGACAC
CATCCCCCAGGACAGGCTCACGGAGGTCATCGCCAGCATCATCAAACCCCAGAACACGTACTGCGTGCGTCGGTATGCCGTGGTCCAGAA
GGCCGCCCATGGGCACGTCCGCAAGGCCTTCAAGAGCCACGTCCTACGTCCAGTGCCAGGGGATCCCGCAGGGCTCCATCCTCTCCACGC
TGCTCTGCAGCCTGTGCTACGGCGACATGGAGAACAAGCTGTTTGCGGGGATTCGGCGGGACGGGCTGCTCCTGCGTTTGGTGGATGATT

>In-frame_ENST00000509581_ENST00000508104_TCGA-BP-4991-01A_PDCD6_chr5_272887_+_TERT_chr5_1282739_length(amino acids)=355AA_start in transcript=10_stop in transcript=1077
MRGLSSLQAPQPSRVPWPMAAYSYRPGPGAGPGPAAGAALPDQSFLWNVFQRVDKDRSGVISDTELQQALSNGVGCVPAAEHRLREEILA
KFLHWLMSVYVVELLRSFFYVTETTFQKNRLFFYRKSVWSKLQSIGIRQHLKRVQLRELSEAEVRQHREARPALLTSRLRFIPKPDGLRP
IVNMDYVVGARTFRREKRAERLTSRVKALFSVLNYERARRPGLLGASVLGLDDIHRAWRTFVLRVRAQDPPPELYFVKVDVTGAYDTIPQ

--------------------------------------------------------------
>In-frame_ENST00000507528_ENST00000310581_TCGA-BP-4991-01A_PDCD6_chr5_272887_+_TERT_chr5_1282739_length(transcript)=2614nt_BP=227nt
CGGAGTCGGCCTGAGAGGTCTCTCGTCGCTGCAGGCGCCTCAGCCCAGCCGCGTGCCTTGGCCCATGGCCGCCTACTCTTACCGCCCCGG
CCCTGGGGCCGGCCCTGGGCCTGCTGCAGGCGCGGCGCTGCCGGACCAGAGCTTCCTGTGGAACGTTTTCCAGAGGGTCGATAAAGACAG
GAGTGGAGTGATATCAGACACCGAGCTTCAGCAAGCTCTCTCCAACGGGGTTGGCTGTGTTCCGGCCGCAGAGCACCGTCTGCGTGAGGA
GATCCTGGCCAAGTTCCTGCACTGGCTGATGAGTGTGTACGTCGTCGAGCTGCTCAGGTCTTTCTTTTATGTCACGGAGACCACGTTTCA
AAAGAACAGGCTCTTTTTCTACCGGAAGAGTGTCTGGAGCAAGTTGCAAAGCATTGGAATCAGACAGCACTTGAAGAGGGTGCAGCTGCG
GGAGCTGTCGGAAGCAGAGGTCAGGCAGCATCGGGAAGCCAGGCCCGCCCTGCTGACGTCCAGACTCCGCTTCATCCCCAAGCCTGACGG
GCTGCGGCCGATTGTGAACATGGACTACGTCGTGGGAGCCAGAACGTTCCGCAGAGAAAAGAGGGCCGAGCGTCTCACCTCGAGGGTGAA
GGCACTGTTCAGCGTGCTCAACTACGAGCGGGCGCGGCGCCCCGGCCTCCTGGGCGCCTCTGTGCTGGGCCTGGACGATATCCACAGGGC
CTGGCGCACCTTCGTGCTGCGTGTGCGGGCCCAGGACCCGCCGCCTGAGCTGTACTTTGTCAAGGTGGATGTGACGGGCGCGTACGACAC
CATCCCCCAGGACAGGCTCACGGAGGTCATCGCCAGCATCATCAAACCCCAGAACACGTACTGCGTGCGTCGGTATGCCGTGGTCCAGAA
GGCCGCCCATGGGCACGTCCGCAAGGCCTTCAAGAGCCACGTCTCTACCTTGACAGACCTCCAGCCGTACATGCGACAGTTCGTGGCTCA
CCTGCAGGAGACCAGCCCGCTGAGGGATGCCGTCGTCATCGAGCAGAGCTCCTCCCTGAATGAGGCCAGCAGTGGCCTCTTCGACGTCTT
CCTACGCTTCATGTGCCACCACGCCGTGCGCATCAGGGGCAAGTCCTACGTCCAGTGCCAGGGGATCCCGCAGGGCTCCATCCTCTCCAC
GCTGCTCTGCAGCCTGTGCTACGGCGACATGGAGAACAAGCTGTTTGCGGGGATTCGGCGGGACGGGCTGCTCCTGCGTTTGGTGGATGA
TTTCTTGTTGGTGACACCTCACCTCACCCACGCGAAAACCTTCCTCAGGACCCTGGTCCGAGGTGTCCCTGAGTATGGCTGCGTGGTGAA
CTTGCGGAAGACAGTGGTGAACTTCCCTGTAGAAGACGAGGCCCTGGGTGGCACGGCTTTTGTTCAGATGCCGGCCCACGGCCTATTCCC
CTGGTGCGGCCTGCTGCTGGATACCCGGACCCTGGAGGTGCAGAGCGACTACTCCAGCTATGCCCGGACCTCCATCAGAGCCAGTCTCAC
CTTCAACCGCGGCTTCAAGGCTGGGAGGAACATGCGTCGCAAACTCTTTGGGGTCTTGCGGCTGAAGTGTCACAGCCTGTTTCTGGATTT
GCAGGTGAACAGCCTCCAGACGGTGTGCACCAACATCTACAAGATCCTCCTGCTGCAGGCGTACAGGTTTCACGCATGTGTGCTGCAGCT
CCCATTTCATCAGCAAGTTTGGAAGAACCCCACATTTTTCCTGCGCGTCATCTCTGACACGGCCTCCCTCTGCTACTCCATCCTGAAAGC
CAAGAACGCAGGGATGTCGCTGGGGGCCAAGGGCGCCGCCGGCCCTCTGCCCTCCGAGGCCGTGCAGTGGCTGTGCCACCAAGCATTCCT
GCTCAAGCTGACTCGACACCGTGTCACCTACGTGCCACTCCTGGGGTCACTCAGGACAGCCCAGACGCAGCTGAGTCGGAAGCTCCCGGG
GACGACGCTGACTGCCCTGGAGGCCGCAGCCAACCCGGCACTGCCCTCAGACTTCAAGACCATCCTGGACTGATGGCCACCCGCCCACAG
CCAGGCCGAGAGCAGACACCAGCAGCCCTGTCACGCCGGGCTCTACGTCCCAGGGAGGGAGGGGCGGCCCACACCCAGGCCCGCACCGCT
GGGAGTCTGAGGCCTGAGTGAGTGTTTGGCCGAGGCCTGCATGTCCGGCTGAAGGCTGAGTGTCCGGCTGAGGCCTGAGCGAGTGTCCAG
CCAAGGGCTGAGTGTCCAGCACACCTGCCGTCTTCACTTCCCCACAGGCTGGCGCTCGGCTCCACCCCAGGGCCAGCTTTTCCTCACCAG
GAGCCCGGCTTCCACTCCCCACATAGGAATAGTCCATCCCCAGATTCGCCATTGTTCACCCCTCGCCCTGCCCTCCTTTGCCTTCCACCC
CCACCATCCAGGTGGAGACCCTGAGAAGGACCCTGGGAGCTCTGGGAATTTGGAGTGACCAAAGGTGTGCCCTGTACACAGGCGAGGACC
CTGCACCTGGATGGGGGTCCCTGTGGGTCAAATTGGGGGGAGGTGCTGTGGGAGTAAAATACTGAATATATGAGTTTTTCAGTTTTGAAA

>In-frame_ENST00000507528_ENST00000310581_TCGA-BP-4991-01A_PDCD6_chr5_272887_+_TERT_chr5_1282739_length(amino acids)=680AA_start in transcript=10_stop in transcript=2052
MRGLSSLQAPQPSRVPWPMAAYSYRPGPGAGPGPAAGAALPDQSFLWNVFQRVDKDRSGVISDTELQQALSNGVGCVPAAEHRLREEILA
KFLHWLMSVYVVELLRSFFYVTETTFQKNRLFFYRKSVWSKLQSIGIRQHLKRVQLRELSEAEVRQHREARPALLTSRLRFIPKPDGLRP
IVNMDYVVGARTFRREKRAERLTSRVKALFSVLNYERARRPGLLGASVLGLDDIHRAWRTFVLRVRAQDPPPELYFVKVDVTGAYDTIPQ
DRLTEVIASIIKPQNTYCVRRYAVVQKAAHGHVRKAFKSHVSTLTDLQPYMRQFVAHLQETSPLRDAVVIEQSSSLNEASSGLFDVFLRF
MCHHAVRIRGKSYVQCQGIPQGSILSTLLCSLCYGDMENKLFAGIRRDGLLLRLVDDFLLVTPHLTHAKTFLRTLVRGVPEYGCVVNLRK
TVVNFPVEDEALGGTAFVQMPAHGLFPWCGLLLDTRTLEVQSDYSSYARTSIRASLTFNRGFKAGRNMRRKLFGVLRLKCHSLFLDLQVN
SLQTVCTNIYKILLLQAYRFHACVLQLPFHQQVWKNPTFFLRVISDTASLCYSILKAKNAGMSLGAKGAAGPLPSEAVQWLCHQAFLLKL

--------------------------------------------------------------
>In-frame_ENST00000507528_ENST00000334602_TCGA-BP-4991-01A_PDCD6_chr5_272887_+_TERT_chr5_1282739_length(transcript)=1864nt_BP=227nt
CGGAGTCGGCCTGAGAGGTCTCTCGTCGCTGCAGGCGCCTCAGCCCAGCCGCGTGCCTTGGCCCATGGCCGCCTACTCTTACCGCCCCGG
CCCTGGGGCCGGCCCTGGGCCTGCTGCAGGCGCGGCGCTGCCGGACCAGAGCTTCCTGTGGAACGTTTTCCAGAGGGTCGATAAAGACAG
GAGTGGAGTGATATCAGACACCGAGCTTCAGCAAGCTCTCTCCAACGGGGTTGGCTGTGTTCCGGCCGCAGAGCACCGTCTGCGTGAGGA
GATCCTGGCCAAGTTCCTGCACTGGCTGATGAGTGTGTACGTCGTCGAGCTGCTCAGGTCTTTCTTTTATGTCACGGAGACCACGTTTCA
AAAGAACAGGCTCTTTTTCTACCGGAAGAGTGTCTGGAGCAAGTTGCAAAGCATTGGAATCAGACAGCACTTGAAGAGGGTGCAGCTGCG
GGAGCTGTCGGAAGCAGAGGTCAGGCAGCATCGGGAAGCCAGGCCCGCCCTGCTGACGTCCAGACTCCGCTTCATCCCCAAGCCTGACGG
GCTGCGGCCGATTGTGAACATGGACTACGTCGTGGGAGCCAGAACGTTCCGCAGAGAAAAGAGGGCCGAGCGTCTCACCTCGAGGGTGAA
GGCACTGTTCAGCGTGCTCAACTACGAGCGGGCGCGGCGCCCCGGCCTCCTGGGCGCCTCTGTGCTGGGCCTGGACGATATCCACAGGGC
CTGGCGCACCTTCGTGCTGCGTGTGCGGGCCCAGGACCCGCCGCCTGAGCTGTACTTTGTCAAGGTGGATGTGACGGGCGCGTACGACAC
CATCCCCCAGGACAGGCTCACGGAGGTCATCGCCAGCATCATCAAACCCCAGAACACGTACTGCGTGCGTCGGTATGCCGTGGTCCAGAA
GGCCGCCCATGGGCACGTCCGCAAGGCCTTCAAGAGCCACGTCTCTACCTTGACAGACCTCCAGCCGTACATGCGACAGTTCGTGGCTCA
CCTGCAGGAGACCAGCCCGCTGAGGGATGCCGTCGTCATCGAGCAGAGCTCCTCCCTGAATGAGGCCAGCAGTGGCCTCTTCGACGTCTT
CCTACGCTTCATGTGCCACCACGCCGTGCGCATCAGGGGCAAGTCCTACGTCCAGTGCCAGGGGATCCCGCAGGGCTCCATCCTCTCCAC
GCTGCTCTGCAGCCTGTGCTACGGCGACATGGAGAACAAGCTGTTTGCGGGGATTCGGCGGGACGGGCTGCTCCTGCGTTTGGTGGATGA
TTTCTTGTTGGTGACACCTCACCTCACCCACGCGAAAACCTTCCTCAGCTATGCCCGGACCTCCATCAGAGCCAGTCTCACCTTCAACCG
CGGCTTCAAGGCTGGGAGGAACATGCGTCGCAAACTCTTTGGGGTCTTGCGGCTGAAGTGTCACAGCCTGTTTCTGGATTTGCAGGTGAA
CAGCCTCCAGACGGTGTGCACCAACATCTACAAGATCCTCCTGCTGCAGGCGTACAGGTTTCACGCATGTGTGCTGCAGCTCCCATTTCA
TCAGCAAGTTTGGAAGAACCCCACATTTTTCCTGCGCGTCATCTCTGACACGGCCTCCCTCTGCTACTCCATCCTGAAAGCCAAGAACGC
AGGGATGTCGCTGGGGGCCAAGGGCGCCGCCGGCCCTCTGCCCTCCGAGGCCGTGCAGTGGCTGTGCCACCAAGCATTCCTGCTCAAGCT
GACTCGACACCGTGTCACCTACGTGCCACTCCTGGGGTCACTCAGGACAGCCCAGACGCAGCTGAGTCGGAAGCTCCCGGGGACGACGCT

>In-frame_ENST00000507528_ENST00000334602_TCGA-BP-4991-01A_PDCD6_chr5_272887_+_TERT_chr5_1282739_length(amino acids)=618AA_start in transcript=10_stop in transcript=1863
MRGLSSLQAPQPSRVPWPMAAYSYRPGPGAGPGPAAGAALPDQSFLWNVFQRVDKDRSGVISDTELQQALSNGVGCVPAAEHRLREEILA
KFLHWLMSVYVVELLRSFFYVTETTFQKNRLFFYRKSVWSKLQSIGIRQHLKRVQLRELSEAEVRQHREARPALLTSRLRFIPKPDGLRP
IVNMDYVVGARTFRREKRAERLTSRVKALFSVLNYERARRPGLLGASVLGLDDIHRAWRTFVLRVRAQDPPPELYFVKVDVTGAYDTIPQ
DRLTEVIASIIKPQNTYCVRRYAVVQKAAHGHVRKAFKSHVSTLTDLQPYMRQFVAHLQETSPLRDAVVIEQSSSLNEASSGLFDVFLRF
MCHHAVRIRGKSYVQCQGIPQGSILSTLLCSLCYGDMENKLFAGIRRDGLLLRLVDDFLLVTPHLTHAKTFLSYARTSIRASLTFNRGFK
AGRNMRRKLFGVLRLKCHSLFLDLQVNSLQTVCTNIYKILLLQAYRFHACVLQLPFHQQVWKNPTFFLRVISDTASLCYSILKAKNAGMS

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>In-frame_ENST00000507528_ENST00000508104_TCGA-BP-4991-01A_PDCD6_chr5_272887_+_TERT_chr5_1282739_length(transcript)=1140nt_BP=227nt
CGGAGTCGGCCTGAGAGGTCTCTCGTCGCTGCAGGCGCCTCAGCCCAGCCGCGTGCCTTGGCCCATGGCCGCCTACTCTTACCGCCCCGG
CCCTGGGGCCGGCCCTGGGCCTGCTGCAGGCGCGGCGCTGCCGGACCAGAGCTTCCTGTGGAACGTTTTCCAGAGGGTCGATAAAGACAG
GAGTGGAGTGATATCAGACACCGAGCTTCAGCAAGCTCTCTCCAACGGGGTTGGCTGTGTTCCGGCCGCAGAGCACCGTCTGCGTGAGGA
GATCCTGGCCAAGTTCCTGCACTGGCTGATGAGTGTGTACGTCGTCGAGCTGCTCAGGTCTTTCTTTTATGTCACGGAGACCACGTTTCA
AAAGAACAGGCTCTTTTTCTACCGGAAGAGTGTCTGGAGCAAGTTGCAAAGCATTGGAATCAGACAGCACTTGAAGAGGGTGCAGCTGCG
GGAGCTGTCGGAAGCAGAGGTCAGGCAGCATCGGGAAGCCAGGCCCGCCCTGCTGACGTCCAGACTCCGCTTCATCCCCAAGCCTGACGG
GCTGCGGCCGATTGTGAACATGGACTACGTCGTGGGAGCCAGAACGTTCCGCAGAGAAAAGAGGGCCGAGCGTCTCACCTCGAGGGTGAA
GGCACTGTTCAGCGTGCTCAACTACGAGCGGGCGCGGCGCCCCGGCCTCCTGGGCGCCTCTGTGCTGGGCCTGGACGATATCCACAGGGC
CTGGCGCACCTTCGTGCTGCGTGTGCGGGCCCAGGACCCGCCGCCTGAGCTGTACTTTGTCAAGGTGGATGTGACGGGCGCGTACGACAC
CATCCCCCAGGACAGGCTCACGGAGGTCATCGCCAGCATCATCAAACCCCAGAACACGTACTGCGTGCGTCGGTATGCCGTGGTCCAGAA
GGCCGCCCATGGGCACGTCCGCAAGGCCTTCAAGAGCCACGTCCTACGTCCAGTGCCAGGGGATCCCGCAGGGCTCCATCCTCTCCACGC
TGCTCTGCAGCCTGTGCTACGGCGACATGGAGAACAAGCTGTTTGCGGGGATTCGGCGGGACGGGCTGCTCCTGCGTTTGGTGGATGATT

>In-frame_ENST00000507528_ENST00000508104_TCGA-BP-4991-01A_PDCD6_chr5_272887_+_TERT_chr5_1282739_length(amino acids)=355AA_start in transcript=10_stop in transcript=1077
MRGLSSLQAPQPSRVPWPMAAYSYRPGPGAGPGPAAGAALPDQSFLWNVFQRVDKDRSGVISDTELQQALSNGVGCVPAAEHRLREEILA
KFLHWLMSVYVVELLRSFFYVTETTFQKNRLFFYRKSVWSKLQSIGIRQHLKRVQLRELSEAEVRQHREARPALLTSRLRFIPKPDGLRP
IVNMDYVVGARTFRREKRAERLTSRVKALFSVLNYERARRPGLLGASVLGLDDIHRAWRTFVLRVRAQDPPPELYFVKVDVTGAYDTIPQ

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Fusion Gene PPI Analysis for PDCD6-TERT


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for PDCD6-TERT


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
HgenePDCD6O75340DB11348Calcium PhosphateAgonistSmall moleculeApproved
HgenePDCD6O75340DB11348Calcium PhosphateAgonistSmall moleculeApproved
HgenePDCD6O75340DB14481Calcium phosphate dihydrateSmall moleculeApproved
HgenePDCD6O75340DB14481Calcium phosphate dihydrateSmall moleculeApproved
HgenePDCD6O75340DB01593ZincSmall moleculeApproved|Investigational
HgenePDCD6O75340DB01593ZincSmall moleculeApproved|Investigational
HgenePDCD6O75340DB11093Calcium citrateAgonistSmall moleculeApproved|Investigational
HgenePDCD6O75340DB11093Calcium citrateAgonistSmall moleculeApproved|Investigational
HgenePDCD6O75340DB14487Zinc acetateSmall moleculeApproved|Investigational
HgenePDCD6O75340DB14487Zinc acetateSmall moleculeApproved|Investigational

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Related Diseases for PDCD6-TERT


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgenePDCD6C0011573Endogenous depression1PSYGENET
TgeneTERTC3151443DYSKERATOSIS CONGENITA, AUTOSOMAL DOMINANT 211CTD_human;GENOMICS_ENGLAND;UNIPROT
TgeneTERTC3553617PULMONARY FIBROSIS AND/OR BONE MARROW FAILURE, TELOMERE-RELATED, 18CTD_human;GENOMICS_ENGLAND;UNIPROT
TgeneTERTC0002874Aplastic Anemia6CTD_human;GENOMICS_ENGLAND;UNIPROT
TgeneTERTC0265965Dyskeratosis Congenita5CTD_human;GENOMICS_ENGLAND
TgeneTERTC1800706Idiopathic Pulmonary Fibrosis5CTD_human;ORPHANET
TgeneTERTC4721508Hamman-Rich Disease5CTD_human
TgeneTERTC4721509Usual Interstitial Pneumonia5CTD_human
TgeneTERTC4721952Familial Idiopathic Pulmonary Fibrosis5CTD_human
TgeneTERTC2239176Liver carcinoma4CTD_human
TgeneTERTC0023467Leukemia, Myelocytic, Acute3CTD_human;GENOMICS_ENGLAND
TgeneTERTC1148551X-Linked Dyskeratosis Congenita3CTD_human
TgeneTERTC1956346Coronary Artery Disease3CTD_human;GENOMICS_ENGLAND
TgeneTERTC0017638Glioma2CTD_human
TgeneTERTC0024121Lung Neoplasms2CTD_human
TgeneTERTC0025202melanoma2CTD_human;GENOMICS_ENGLAND
TgeneTERTC0030297Pancreatic Neoplasm2CTD_human
TgeneTERTC0033578Prostatic Neoplasms2CTD_human
TgeneTERTC0242379Malignant neoplasm of lung2CTD_human
TgeneTERTC0259783mixed gliomas2CTD_human
TgeneTERTC0334488Clear cell sarcoma of kidney2ORPHANET
TgeneTERTC0346647Malignant neoplasm of pancreas2CTD_human
TgeneTERTC0348890Aplastic anemia, idiopathic2ORPHANET
TgeneTERTC0376358Malignant neoplasm of prostate2CTD_human
TgeneTERTC0555198Malignant Glioma2CTD_human
TgeneTERTC1846142HOYERAAL-HREIDARSSON SYNDROME2CTD_human;GENOMICS_ENGLAND;ORPHANET
TgeneTERTC3554574MELANOMA, CUTANEOUS MALIGNANT, SUSCEPTIBILITY TO, 92CTD_human;GENOMICS_ENGLAND
TgeneTERTC0005684Malignant neoplasm of urinary bladder1CTD_human
TgeneTERTC0005695Bladder Neoplasm1CTD_human
TgeneTERTC0006142Malignant neoplasm of breast1CTD_human
TgeneTERTC0006826Malignant Neoplasms1CTD_human
TgeneTERTC0007131Non-Small Cell Lung Carcinoma1CTD_human
TgeneTERTC0007873Uterine Cervical Neoplasm1CTD_human
TgeneTERTC0010054Coronary Arteriosclerosis1CTD_human
TgeneTERTC0010314Cri-du-Chat Syndrome1CTD_human
TgeneTERTC0022658Kidney Diseases1CTD_human
TgeneTERTC0023448Lymphoid leukemia1CTD_human
TgeneTERTC0023473Myeloid Leukemia, Chronic1CTD_human
TgeneTERTC0023903Liver neoplasms1CTD_human
TgeneTERTC0024115Lung diseases1GENOMICS_ENGLAND
TgeneTERTC0024141Lupus Erythematosus, Systemic1CTD_human
TgeneTERTC0027022Myeloproliferative disease1CTD_human
TgeneTERTC0027651Neoplasms1CTD_human
TgeneTERTC0027819Neuroblastoma1CTD_human
TgeneTERTC0035126Reperfusion Injury1CTD_human
TgeneTERTC0040136Thyroid Neoplasm1CTD_human
TgeneTERTC0041696Unipolar Depression1PSYGENET
TgeneTERTC0085786Hamman-Rich syndrome1ORPHANET
TgeneTERTC0086692Benign Neoplasm1CTD_human
TgeneTERTC0151468Thyroid Gland Follicular Adenoma1CTD_human
TgeneTERTC0178416Hypoplastic anemia1CTD_human
TgeneTERTC0206686Adrenocortical carcinoma1CTD_human
TgeneTERTC0235874Disease Exacerbation1CTD_human
TgeneTERTC0242380Libman-Sacks Disease1CTD_human
TgeneTERTC0345904Malignant neoplasm of liver1CTD_human
TgeneTERTC0549473Thyroid carcinoma1CTD_human
TgeneTERTC0678222Breast Carcinoma1CTD_human
TgeneTERTC0919267ovarian neoplasm1CTD_human
TgeneTERTC1140680Malignant neoplasm of ovary1CTD_human
TgeneTERTC1257931Mammary Neoplasms, Human1CTD_human
TgeneTERTC1269683Major Depressive Disorder1PSYGENET
TgeneTERTC1368275Pigmented Basal Cell Carcinoma1CTD_human
TgeneTERTC1458155Mammary Neoplasms1CTD_human
TgeneTERTC2314896Familial Atypical Mole Melanoma Syndrome1ORPHANET
TgeneTERTC3151444DYSKERATOSIS CONGENITA, AUTOSOMAL RECESSIVE, 41GENOMICS_ENGLAND
TgeneTERTC4048328cervical cancer1CTD_human
TgeneTERTC4704874Mammary Carcinoma, Human1CTD_human
TgeneTERTC4721806Carcinoma, Basal Cell1CTD_human