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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:PDE4D-KHDRBS3 (FusionGDB2 ID:63324)

Fusion Gene Summary for PDE4D-KHDRBS3

check button Fusion gene summary
Fusion gene informationFusion gene name: PDE4D-KHDRBS3
Fusion gene ID: 63324
HgeneTgene
Gene symbol

PDE4D

KHDRBS3

Gene ID

5144

10656

Gene namephosphodiesterase 4DKH RNA binding domain containing, signal transduction associated 3
SynonymsACRDYS2|DPDE3|HSPDE4D|PDE43|PDE4DN2|STRK1Etle|SALP|SLM-2|SLM2|T-STAR|TSTAR|etoile
Cytomap

5q11.2-q12.1

8q24.23

Type of geneprotein-codingprotein-coding
DescriptioncAMP-specific 3',5'-cyclic phosphodiesterase 4DcAMP-specific phosphodiesterase PDE4D6phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila)testicular tissue protein Li 136KH domain-containing, RNA-binding, signal transduction-associated protein 3KH domain containing, RNA binding, signal transduction associated 3RNA-binding protein T-StarSam68-like phosphotyrosine protein, T-STARsam68-like mammalian protein 2
Modification date2020031320200313
UniProtAcc.

O75525

Ensembl transtripts involved in fusion geneENST00000340635, ENST00000360047, 
ENST00000507116, ENST00000502484, 
ENST00000546160, ENST00000502575, 
ENST00000358923, ENST00000503258, 
ENST00000405755, ENST00000317118, 
ENST00000503947, 		ENST00000355849, 
ENST00000520981, ENST00000522578, 
Fusion gene scores* DoF score40 X 32 X 12=1536011 X 10 X 10=1100
# samples 5614
** MAII scorelog2(56/15360*10)=-4.77760757866355
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(14/1100*10)=-2.97400479146706
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: PDE4D [Title/Abstract] AND KHDRBS3 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointPDE4D(58476421)-KHDRBS3(136533480), # samples:3
Anticipated loss of major functional domain due to fusion event.PDE4D-KHDRBS3 seems lost the major protein functional domain in Hgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
PDE4D-KHDRBS3 seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across PDE4D (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across KHDRBS3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUSCTCGA-63-A5MY-01APDE4Dchr5

58476421

-KHDRBS3chr8

136533480

+
ChimerDB4LUSCTCGA-63-A5MYPDE4Dchr5

58476421

-KHDRBS3chr8

136533480

+
ChimerDB4LUSCTCGA-63-A5MY-01APDE4Dchr5

58476421

-KHDRBS3chr8

136533480

+


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Fusion Gene ORF analysis for PDE4D-KHDRBS3

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000340635ENST00000355849PDE4Dchr5

58476421

-KHDRBS3chr8

136533480

+
In-frameENST00000340635ENST00000520981PDE4Dchr5

58476421

-KHDRBS3chr8

136533480

+
5CDS-intronENST00000340635ENST00000522578PDE4Dchr5

58476421

-KHDRBS3chr8

136533480

+
In-frameENST00000360047ENST00000355849PDE4Dchr5

58476421

-KHDRBS3chr8

136533480

+
In-frameENST00000360047ENST00000520981PDE4Dchr5

58476421

-KHDRBS3chr8

136533480

+
5CDS-intronENST00000360047ENST00000522578PDE4Dchr5

58476421

-KHDRBS3chr8

136533480

+
In-frameENST00000507116ENST00000355849PDE4Dchr5

58476421

-KHDRBS3chr8

136533480

+
In-frameENST00000507116ENST00000520981PDE4Dchr5

58476421

-KHDRBS3chr8

136533480

+
5CDS-intronENST00000507116ENST00000522578PDE4Dchr5

58476421

-KHDRBS3chr8

136533480

+
Frame-shiftENST00000502484ENST00000355849PDE4Dchr5

58476421

-KHDRBS3chr8

136533480

+
Frame-shiftENST00000502484ENST00000520981PDE4Dchr5

58476421

-KHDRBS3chr8

136533480

+
5CDS-intronENST00000502484ENST00000522578PDE4Dchr5

58476421

-KHDRBS3chr8

136533480

+
In-frameENST00000546160ENST00000355849PDE4Dchr5

58476421

-KHDRBS3chr8

136533480

+
In-frameENST00000546160ENST00000520981PDE4Dchr5

58476421

-KHDRBS3chr8

136533480

+
5CDS-intronENST00000546160ENST00000522578PDE4Dchr5

58476421

-KHDRBS3chr8

136533480

+
In-frameENST00000502575ENST00000355849PDE4Dchr5

58476421

-KHDRBS3chr8

136533480

+
In-frameENST00000502575ENST00000520981PDE4Dchr5

58476421

-KHDRBS3chr8

136533480

+
5CDS-intronENST00000502575ENST00000522578PDE4Dchr5

58476421

-KHDRBS3chr8

136533480

+
intron-3CDSENST00000358923ENST00000355849PDE4Dchr5

58476421

-KHDRBS3chr8

136533480

+
intron-3CDSENST00000358923ENST00000520981PDE4Dchr5

58476421

-KHDRBS3chr8

136533480

+
intron-intronENST00000358923ENST00000522578PDE4Dchr5

58476421

-KHDRBS3chr8

136533480

+
In-frameENST00000503258ENST00000355849PDE4Dchr5

58476421

-KHDRBS3chr8

136533480

+
In-frameENST00000503258ENST00000520981PDE4Dchr5

58476421

-KHDRBS3chr8

136533480

+
5CDS-intronENST00000503258ENST00000522578PDE4Dchr5

58476421

-KHDRBS3chr8

136533480

+
In-frameENST00000405755ENST00000355849PDE4Dchr5

58476421

-KHDRBS3chr8

136533480

+
In-frameENST00000405755ENST00000520981PDE4Dchr5

58476421

-KHDRBS3chr8

136533480

+
5CDS-intronENST00000405755ENST00000522578PDE4Dchr5

58476421

-KHDRBS3chr8

136533480

+
intron-3CDSENST00000317118ENST00000355849PDE4Dchr5

58476421

-KHDRBS3chr8

136533480

+
intron-3CDSENST00000317118ENST00000520981PDE4Dchr5

58476421

-KHDRBS3chr8

136533480

+
intron-intronENST00000317118ENST00000522578PDE4Dchr5

58476421

-KHDRBS3chr8

136533480

+
5UTR-3CDSENST00000503947ENST00000355849PDE4Dchr5

58476421

-KHDRBS3chr8

136533480

+
5UTR-3CDSENST00000503947ENST00000520981PDE4Dchr5

58476421

-KHDRBS3chr8

136533480

+
5UTR-intronENST00000503947ENST00000522578PDE4Dchr5

58476421

-KHDRBS3chr8

136533480

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000340635PDE4Dchr558476421-ENST00000355849KHDRBS3chr8136533480+24639841761936586
ENST00000340635PDE4Dchr558476421-ENST00000520981KHDRBS3chr8136533480+18639841761336386
ENST00000360047PDE4Dchr558476421-ENST00000355849KHDRBS3chr8136533480+2003524311476481
ENST00000360047PDE4Dchr558476421-ENST00000520981KHDRBS3chr8136533480+140352431876281
ENST00000507116PDE4Dchr558476421-ENST00000355849KHDRBS3chr8136533480+223175271704565
ENST00000507116PDE4Dchr558476421-ENST00000520981KHDRBS3chr8136533480+163175271104365
ENST00000546160PDE4Dchr558476421-ENST00000355849KHDRBS3chr8136533480+210462501577525
ENST00000546160PDE4Dchr558476421-ENST00000520981KHDRBS3chr8136533480+15046250977325
ENST00000502575PDE4Dchr558476421-ENST00000355849KHDRBS3chr8136533480+2222743491695548
ENST00000502575PDE4Dchr558476421-ENST00000520981KHDRBS3chr8136533480+1622743491095348
ENST00000503258PDE4Dchr558476421-ENST00000355849KHDRBS3chr8136533480+261411357172087456
ENST00000503258PDE4Dchr558476421-ENST00000520981KHDRBS3chr8136533480+201411357171487256
ENST00000405755PDE4Dchr558476421-ENST00000355849KHDRBS3chr8136533480+20505711021523473
ENST00000405755PDE4Dchr558476421-ENST00000520981KHDRBS3chr8136533480+1450571102923273

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000340635ENST00000355849PDE4Dchr558476421-KHDRBS3chr8136533480+0.0032126490.9967873
ENST00000340635ENST00000520981PDE4Dchr558476421-KHDRBS3chr8136533480+0.0023090820.9976909
ENST00000360047ENST00000355849PDE4Dchr558476421-KHDRBS3chr8136533480+0.0001871440.9998129
ENST00000360047ENST00000520981PDE4Dchr558476421-KHDRBS3chr8136533480+0.0002449320.9997551
ENST00000507116ENST00000355849PDE4Dchr558476421-KHDRBS3chr8136533480+0.0006896820.9993104
ENST00000507116ENST00000520981PDE4Dchr558476421-KHDRBS3chr8136533480+0.0002772010.9997228
ENST00000546160ENST00000355849PDE4Dchr558476421-KHDRBS3chr8136533480+0.0001977020.9998023
ENST00000546160ENST00000520981PDE4Dchr558476421-KHDRBS3chr8136533480+0.0001144280.99988556
ENST00000502575ENST00000355849PDE4Dchr558476421-KHDRBS3chr8136533480+0.0006672630.9993327
ENST00000502575ENST00000520981PDE4Dchr558476421-KHDRBS3chr8136533480+0.0002518720.9997482
ENST00000503258ENST00000355849PDE4Dchr558476421-KHDRBS3chr8136533480+0.0002028230.99979717
ENST00000503258ENST00000520981PDE4Dchr558476421-KHDRBS3chr8136533480+0.0007002460.99929976
ENST00000405755ENST00000355849PDE4Dchr558476421-KHDRBS3chr8136533480+0.0001997180.99980026
ENST00000405755ENST00000520981PDE4Dchr558476421-KHDRBS3chr8136533480+0.0002089550.9997911

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Fusion Genomic Features for PDE4D-KHDRBS3


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
PDE4Dchr558476420-KHDRBS3chr8136533479+3.10E-050.999969
PDE4Dchr558476420-KHDRBS3chr8136533479+3.10E-050.999969
PDE4Dchr558476420-KHDRBS3chr8136533479+3.10E-050.999969
PDE4Dchr558476420-KHDRBS3chr8136533479+3.10E-050.999969

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for PDE4D-KHDRBS3


check button Go to

FGviewer for the breakpoints of chr5:58476421-chr8:136533480

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.KHDRBS3

O75525

FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Binds preferentially to the 5'-[AU]UAAA-3' motif in vitro. Binds optimally to RNA containing 5'-[AU]UAA-3' as a bipartite motif spaced by more than 15 nucleotides. Binds poly(A). RNA-binding abilities are down-regulated by tyrosine kinase PTK6 (PubMed:10564820, PubMed:19561594, PubMed:26758068). Involved in splice site selection of vascular endothelial growth factor (PubMed:15901763). In vitro regulates CD44 alternative splicing by direct binding to purine-rich exonic enhancer (By similarity). Can regulate alternative splicing of neurexins NRXN1-3 in the laminin G-like domain 6 containing the evolutionary conserved neurexin alternative spliced segment 4 (AS4) involved in neurexin selective targeting to postsynaptic partners such as neuroligins and LRRTM family members (PubMed:26758068). Targeted, cell-type specific splicing regulation of NRXN1 at AS4 is involved in neuronal glutamatergic synapse function and plasticity (By similarity). May regulate expression of KHDRBS2/SLIM-1 in defined brain neuron populations by modifying its alternative splicing (By similarity). Can bind FABP9 mRNA (By similarity). May play a role as a negative regulator of cell growth. Inhibits cell proliferation. {ECO:0000250|UniProtKB:Q9JLP1, ECO:0000250|UniProtKB:Q9R226, ECO:0000269|PubMed:10564820, ECO:0000269|PubMed:15901763, ECO:0000269|PubMed:19561594, ECO:0000269|PubMed:26758068}.; FUNCTION: (Microbial infection) Involved in post-transcriptional regulation of HIV-1 gene expression. {ECO:0000269|PubMed:11741900}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePDE4Dchr5:58476421chr8:136533480ENST00000340635-51542_88269.3333333333333810.0Compositional biasNote=Pro-rich
HgenePDE4Dchr5:58476421chr8:136533480ENST00000360047-51542_88133.33333333333334674.0Compositional biasNote=Pro-rich
HgenePDE4Dchr5:58476421chr8:136533480ENST00000405755-51542_88147.33333333333334688.0Compositional biasNote=Pro-rich
HgenePDE4Dchr5:58476421chr8:136533480ENST00000502484-71742_88208.33333333333334749.0Compositional biasNote=Pro-rich
HgenePDE4Dchr5:58476421chr8:136533480ENST00000502575-5642_88205.33333333333334220.0Compositional biasNote=Pro-rich
HgenePDE4Dchr5:58476421chr8:136533480ENST00000503258-51542_88139.33333333333334680.0Compositional biasNote=Pro-rich
HgenePDE4Dchr5:58476421chr8:136533480ENST00000507116-51542_88205.33333333333334746.0Compositional biasNote=Pro-rich
HgenePDE4Dchr5:58476421chr8:136533480ENST00000546160-61642_88208.33333333333334749.0Compositional biasNote=Pro-rich
TgeneKHDRBS3chr5:58476421chr8:136533480ENST0000035584909250_26129.333333333333332347.0Compositional biasNote=Pro-rich
TgeneKHDRBS3chr5:58476421chr8:136533480ENST0000035584909266_31629.333333333333332347.0Compositional biasNote=Tyr-rich
TgeneKHDRBS3chr5:58476421chr8:136533480ENST000003558490961_12729.333333333333332347.0DomainNote=KH

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePDE4Dchr5:58476421chr8:136533480ENST00000317118-11042_880519.0Compositional biasNote=Pro-rich
HgenePDE4Dchr5:58476421chr8:136533480ENST00000358923-11142_880508.0Compositional biasNote=Pro-rich
HgenePDE4Dchr5:58476421chr8:136533480ENST00000317118-110386_7150519.0DomainPDEase
HgenePDE4Dchr5:58476421chr8:136533480ENST00000340635-515386_715269.3333333333333810.0DomainPDEase
HgenePDE4Dchr5:58476421chr8:136533480ENST00000358923-111386_7150508.0DomainPDEase
HgenePDE4Dchr5:58476421chr8:136533480ENST00000360047-515386_715133.33333333333334674.0DomainPDEase
HgenePDE4Dchr5:58476421chr8:136533480ENST00000405755-515386_715147.33333333333334688.0DomainPDEase
HgenePDE4Dchr5:58476421chr8:136533480ENST00000502484-717386_715208.33333333333334749.0DomainPDEase
HgenePDE4Dchr5:58476421chr8:136533480ENST00000502575-56386_715205.33333333333334220.0DomainPDEase
HgenePDE4Dchr5:58476421chr8:136533480ENST00000503258-515386_715139.33333333333334680.0DomainPDEase
HgenePDE4Dchr5:58476421chr8:136533480ENST00000507116-515386_715205.33333333333334746.0DomainPDEase
HgenePDE4Dchr5:58476421chr8:136533480ENST00000546160-616386_715208.33333333333334749.0DomainPDEase
HgenePDE4Dchr5:58476421chr8:136533480ENST00000317118-110462_4660519.0Nucleotide bindingcAMP
HgenePDE4Dchr5:58476421chr8:136533480ENST00000340635-515462_466269.3333333333333810.0Nucleotide bindingcAMP
HgenePDE4Dchr5:58476421chr8:136533480ENST00000358923-111462_4660508.0Nucleotide bindingcAMP
HgenePDE4Dchr5:58476421chr8:136533480ENST00000360047-515462_466133.33333333333334674.0Nucleotide bindingcAMP
HgenePDE4Dchr5:58476421chr8:136533480ENST00000405755-515462_466147.33333333333334688.0Nucleotide bindingcAMP
HgenePDE4Dchr5:58476421chr8:136533480ENST00000502484-717462_466208.33333333333334749.0Nucleotide bindingcAMP
HgenePDE4Dchr5:58476421chr8:136533480ENST00000502575-56462_466205.33333333333334220.0Nucleotide bindingcAMP
HgenePDE4Dchr5:58476421chr8:136533480ENST00000503258-515462_466139.33333333333334680.0Nucleotide bindingcAMP
HgenePDE4Dchr5:58476421chr8:136533480ENST00000507116-515462_466205.33333333333334746.0Nucleotide bindingcAMP
HgenePDE4Dchr5:58476421chr8:136533480ENST00000546160-616462_466208.33333333333334749.0Nucleotide bindingcAMP
TgeneKHDRBS3chr5:58476421chr8:136533480ENST00000355849091_16029.333333333333332347.0RegionInvolved in homodimerization


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Fusion Gene Sequence for PDE4D-KHDRBS3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000340635_ENST00000355849_TCGA-63-A5MY-01A_PDE4D_chr5_58476421_-_KHDRBS3_chr8_136533480_length(transcript)=2463nt_BP=984nt
GGGCCCCCTCTCGGTAGCCCTGAGGCTCTGGCGCCTTCAAGTGAGAAGCTAAGCACCAGCCTCTGCTGGGCTGCAGAAGCGGCGGCGGCG
GCAGCAGCAGCAGCAGCATCAGGAAGGCGCTCGGGCCAGCGCGGTGAACCCGGGCTGGGCAGCAGGTCGCGGAGCCGCGAGCCAGGATGG
AGGCAGAGGGCAGCAGCGCGCCGGCCCGGGCGGGCAGCGGAGAGGGCAGCGACAGCGCCGGCGGGGCCACGCTCAAAGCCCCCAAGCATC
TCTGGAGGCACGAGCAGCACCACCAGTACCCGCTCCGGCAGCCCCAGTTCCGCCTCCTGCATCCCCATCACCACCTGCCCCCGCCGCCGC
CACCCTCGCCCCAGCCCCAGCCCCAGTGTCCGCTACAGCCGCCGCCGCCGCCCCCCCTGCCGCCGCCCCCGCCGCCGCCCGGGGCTGCCC
GCGGCCGCTACGCCTCGAGCGGGGCCACCGGCCGCGTCCGGCATCGCGGCTACTCGGACACCGAGCGCTACCTGTACTGTCGCGCCATGG
ACCGCACCTCCTACGCGGTGGAGACCGGCCACCGGCCCGGCCTGAAGAAATCCAGGATGTCCTGGCCCTCCTCGTTCCAGGGACTCAGGC
GTTTTGATGTGGACAATGGCACATCTGCGGGACGGAGTCCCTTGGATCCCATGACCAGCCCAGGATCCGGGCTAATTCTCCAAGCAAATT
TTGTCCACAGTCAACGACGGGAGTCCTTCCTGTATCGATCCGACAGCGATTATGACCTCTCTCCAAAGTCTATGTCCCGGAACTCCTCCA
TTGCCAGTGATATACACGGAGATGACTTGATTGTGACTCCATTTGCTCAGGTCTTGGCCAGTCTGCGAACTGTACGAAACAACTTTGCTG
CATTAACTAATTTGCAAGATCGAGCACCTAGCAAAAGATCACCCATGTGCAACCAACCATCCATCAACAAAGCCACCATAACAGAAATAG
AAAAGTTTCAAAAAGGAGAAGGCAAGGATGAAGAAAAGTACATCGATGTGGTGATTAATAAGAACATGAAGCTGGGACAGAAAGTGTTAA
TTCCCGTAAAACAGTTCCCTAAGTTCAACTTTGTGGGGAAACTTTTGGGTCCACGTGGCAATTCTCTGAAGCGTTTACAAGAAGAAACCT
TGACAAAAATGTCCATCCTTGGGAAAGGTTCCATGAGAGACAAGGCCAAGGAAGAAGAGTTGAGGAAAAGTGGAGAAGCGAAGTACTTCC
ATCTCAATGATGATCTCCATGTTCTCATTGAAGTGTTTGCCCCACCTGCAGAAGCTTATGCCAGGATGGGACATGCTTTGGAAGAAATCA
AAAAGTTCCTCATCCCTGATTATAATGATGAGATCAGGCAAGCACAGCTCCAGGAGTTAACATATTTGAATGGTGGTTCAGAAAATGCAG
ATGTTCCAGTGGTTCGAGGGAAACCCACCTTGCGTACAAGAGGTGTACCAGCCCCAGCAATAACCAGGGGAAGGGGAGGAGTTACAGCCC
GGCCAGTTGGAGTTGTAGTACCACGAGGGACGCCAACTCCCAGAGGAGTCCTGTCCACCCGAGGGCCAGTGAGTCGGGGAAGAGGACTTC
TCACTCCCAGAGCAAGAGGAGTCCCCCCAACTGGGTACAGACCTCCACCGCCACCCCCGACACAAGAGACTTATGGAGAATATGACTATG
ATGATGGATATGGCACTGCTTATGATGAACAGAGTTATGATTCCTATGATAACAGCTATAGCACCCCAGCCCAAAGTGGTGCTGATTACT
ATGATTACGGACATGGACTCAGTGAGGAGACTTATGATTCCTACGGGCAAGAAGAGTGGACTAACTCAAGACACAAGGCACCTTCAGCGA
GGACAGCAAAGGGCGTCTACAGAGACCAGCCATATGGCAGATACTGATTGTACTGTCTGATGTTGTGAAATAGCCAATCTCCACCAGTCC
TGTATACTGTTCAAAGTAATTTTTTTCTATGAACAATCCCTTTTTAAATAAATCAGAATGCTTAAAATCTGAATGGATGGAACTTAAAAC
TACTTTGTTGAAACATCAACCTGGGCAGAAAAAAAAAAAAAAAGACATGTAAAATTTTGTTATTTCCAGTCTGTATATGAAAAAATAGGT
CATCAAAAGGAAAAAAAATAACTTTGATTAACTAGTGTTAAACAAAAAATAGGTTTACTAAATATGTTAATCTATTCTTTTAACATAAGC
CTCACCTTTCATTTTAAAGGTTTCCATAGAATTTAGTTATTTTATCTTTCAGCCATATGCTAGTTTTTTTTTCTCTTGCCAACATGCGTA
AAAAGGGAAGCCAATTACAAGTGCAAATAATGTGGTATTCTTTTGTAACTCAAGTCTTGAAATGTTCTGTAGTGTTAAGCAAAGTCTCCT

>In-frame_ENST00000340635_ENST00000355849_TCGA-63-A5MY-01A_PDE4D_chr5_58476421_-_KHDRBS3_chr8_136533480_length(amino acids)=586AA_start in transcript=176_stop in transcript=1936
MEAEGSSAPARAGSGEGSDSAGGATLKAPKHLWRHEQHHQYPLRQPQFRLLHPHHHLPPPPPPSPQPQPQCPLQPPPPPPLPPPPPPPGA
ARGRYASSGATGRVRHRGYSDTERYLYCRAMDRTSYAVETGHRPGLKKSRMSWPSSFQGLRRFDVDNGTSAGRSPLDPMTSPGSGLILQA
NFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITE
IEKFQKGEGKDEEKYIDVVINKNMKLGQKVLIPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRKSGEAKY
FHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFLIPDYNDEIRQAQLQELTYLNGGSENADVPVVRGKPTLRTRGVPAPAITRGRGGVT
ARPVGVVVPRGTPTPRGVLSTRGPVSRGRGLLTPRARGVPPTGYRPPPPPPTQETYGEYDYDDGYGTAYDEQSYDSYDNSYSTPAQSGAD

--------------------------------------------------------------
>In-frame_ENST00000340635_ENST00000520981_TCGA-63-A5MY-01A_PDE4D_chr5_58476421_-_KHDRBS3_chr8_136533480_length(transcript)=1863nt_BP=984nt
GGGCCCCCTCTCGGTAGCCCTGAGGCTCTGGCGCCTTCAAGTGAGAAGCTAAGCACCAGCCTCTGCTGGGCTGCAGAAGCGGCGGCGGCG
GCAGCAGCAGCAGCAGCATCAGGAAGGCGCTCGGGCCAGCGCGGTGAACCCGGGCTGGGCAGCAGGTCGCGGAGCCGCGAGCCAGGATGG
AGGCAGAGGGCAGCAGCGCGCCGGCCCGGGCGGGCAGCGGAGAGGGCAGCGACAGCGCCGGCGGGGCCACGCTCAAAGCCCCCAAGCATC
TCTGGAGGCACGAGCAGCACCACCAGTACCCGCTCCGGCAGCCCCAGTTCCGCCTCCTGCATCCCCATCACCACCTGCCCCCGCCGCCGC
CACCCTCGCCCCAGCCCCAGCCCCAGTGTCCGCTACAGCCGCCGCCGCCGCCCCCCCTGCCGCCGCCCCCGCCGCCGCCCGGGGCTGCCC
GCGGCCGCTACGCCTCGAGCGGGGCCACCGGCCGCGTCCGGCATCGCGGCTACTCGGACACCGAGCGCTACCTGTACTGTCGCGCCATGG
ACCGCACCTCCTACGCGGTGGAGACCGGCCACCGGCCCGGCCTGAAGAAATCCAGGATGTCCTGGCCCTCCTCGTTCCAGGGACTCAGGC
GTTTTGATGTGGACAATGGCACATCTGCGGGACGGAGTCCCTTGGATCCCATGACCAGCCCAGGATCCGGGCTAATTCTCCAAGCAAATT
TTGTCCACAGTCAACGACGGGAGTCCTTCCTGTATCGATCCGACAGCGATTATGACCTCTCTCCAAAGTCTATGTCCCGGAACTCCTCCA
TTGCCAGTGATATACACGGAGATGACTTGATTGTGACTCCATTTGCTCAGGTCTTGGCCAGTCTGCGAACTGTACGAAACAACTTTGCTG
CATTAACTAATTTGCAAGATCGAGCACCTAGCAAAAGATCACCCATGTGCAACCAACCATCCATCAACAAAGCCACCATAACAGAAATAG
AAAAGTTTCAAAAAGGAGAAGGCAAGGATGAAGAAAAGTACATCGATGTGGTGATTAATAAGAACATGAAGCTGGGACAGAAAGTGTTAA
TTCCCGTAAAACAGTTCCCTAAGGACTATGATGATGGATATGGCACTGCTTATGATGAACAGAGTTATGATTCCTATGATAACAGCTATA
GCACCCCAGCCCAAAGTGGTGCTGATTACTATGATTACGGACATGGACTCAGTGAGGAGACTTATGATTCCTACGGGCAAGAAGAGTGGA
CTAACTCAAGACACAAGGCACCTTCAGCGAGGACAGCAAAGGGCGTCTACAGAGACCAGCCATATGGCAGATACTGATTGTACTGTCTGA
TGTTGTGAAATAGCCAATCTCCACCAGTCCTGTATACTGTTCAAAGTAATTTTTTTCTATGAACAATCCCTTTTTAAATAAATCAGAATG
CTTAAAATCTGAATGGATGGAACTTAAAACTACTTTGTTGAAACATCAACCTGGGCAGAAAAAAAAAAAAAAAGACATGTAAAATTTTGT
TATTTCCAGTCTGTATATGAAAAAATAGGTCATCAAAAGGAAAAAAAATAACTTTGATTAACTAGTGTTAAACAAAAAATAGGTTTACTA
AATATGTTAATCTATTCTTTTAACATAAGCCTCACCTTTCATTTTAAAGGTTTCCATAGAATTTAGTTATTTTATCTTTCAGCCATATGC
TAGTTTTTTTTTCTCTTGCCAACATGCGTAAAAAGGGAAGCCAATTACAAGTGCAAATAATGTGGTATTCTTTTGTAACTCAAGTCTTGA

>In-frame_ENST00000340635_ENST00000520981_TCGA-63-A5MY-01A_PDE4D_chr5_58476421_-_KHDRBS3_chr8_136533480_length(amino acids)=386AA_start in transcript=176_stop in transcript=1336
MEAEGSSAPARAGSGEGSDSAGGATLKAPKHLWRHEQHHQYPLRQPQFRLLHPHHHLPPPPPPSPQPQPQCPLQPPPPPPLPPPPPPPGA
ARGRYASSGATGRVRHRGYSDTERYLYCRAMDRTSYAVETGHRPGLKKSRMSWPSSFQGLRRFDVDNGTSAGRSPLDPMTSPGSGLILQA
NFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITE
IEKFQKGEGKDEEKYIDVVINKNMKLGQKVLIPVKQFPKDYDDGYGTAYDEQSYDSYDNSYSTPAQSGADYYDYGHGLSEETYDSYGQEE

--------------------------------------------------------------
>In-frame_ENST00000360047_ENST00000355849_TCGA-63-A5MY-01A_PDE4D_chr5_58476421_-_KHDRBS3_chr8_136533480_length(transcript)=2003nt_BP=524nt
CAATACTTGTTGCAATAATTGCCCACGATAGCTGCTCAAACAAGAGAGTTGGAATTCATCTGTAAAAATCACTACATGTAACGTAGGAGA
CAAGAAAAATATTAATGACAGAAGATCTGCGAACATGATGCACGTGAATAATTTTCCCTTTAGAAGGCATTCCTGGATATGTTTTGATGT
GGACAATGGCACATCTGCGGGACGGAGTCCCTTGGATCCCATGACCAGCCCAGGATCCGGGCTAATTCTCCAAGCAAATTTTGTCCACAG
TCAACGACGGGAGTCCTTCCTGTATCGATCCGACAGCGATTATGACCTCTCTCCAAAGTCTATGTCCCGGAACTCCTCCATTGCCAGTGA
TATACACGGAGATGACTTGATTGTGACTCCATTTGCTCAGGTCTTGGCCAGTCTGCGAACTGTACGAAACAACTTTGCTGCATTAACTAA
TTTGCAAGATCGAGCACCTAGCAAAAGATCACCCATGTGCAACCAACCATCCATCAACAAAGCCACCATAACAGAAATAGAAAAGTTTCA
AAAAGGAGAAGGCAAGGATGAAGAAAAGTACATCGATGTGGTGATTAATAAGAACATGAAGCTGGGACAGAAAGTGTTAATTCCCGTAAA
ACAGTTCCCTAAGTTCAACTTTGTGGGGAAACTTTTGGGTCCACGTGGCAATTCTCTGAAGCGTTTACAAGAAGAAACCTTGACAAAAAT
GTCCATCCTTGGGAAAGGTTCCATGAGAGACAAGGCCAAGGAAGAAGAGTTGAGGAAAAGTGGAGAAGCGAAGTACTTCCATCTCAATGA
TGATCTCCATGTTCTCATTGAAGTGTTTGCCCCACCTGCAGAAGCTTATGCCAGGATGGGACATGCTTTGGAAGAAATCAAAAAGTTCCT
CATCCCTGATTATAATGATGAGATCAGGCAAGCACAGCTCCAGGAGTTAACATATTTGAATGGTGGTTCAGAAAATGCAGATGTTCCAGT
GGTTCGAGGGAAACCCACCTTGCGTACAAGAGGTGTACCAGCCCCAGCAATAACCAGGGGAAGGGGAGGAGTTACAGCCCGGCCAGTTGG
AGTTGTAGTACCACGAGGGACGCCAACTCCCAGAGGAGTCCTGTCCACCCGAGGGCCAGTGAGTCGGGGAAGAGGACTTCTCACTCCCAG
AGCAAGAGGAGTCCCCCCAACTGGGTACAGACCTCCACCGCCACCCCCGACACAAGAGACTTATGGAGAATATGACTATGATGATGGATA
TGGCACTGCTTATGATGAACAGAGTTATGATTCCTATGATAACAGCTATAGCACCCCAGCCCAAAGTGGTGCTGATTACTATGATTACGG
ACATGGACTCAGTGAGGAGACTTATGATTCCTACGGGCAAGAAGAGTGGACTAACTCAAGACACAAGGCACCTTCAGCGAGGACAGCAAA
GGGCGTCTACAGAGACCAGCCATATGGCAGATACTGATTGTACTGTCTGATGTTGTGAAATAGCCAATCTCCACCAGTCCTGTATACTGT
TCAAAGTAATTTTTTTCTATGAACAATCCCTTTTTAAATAAATCAGAATGCTTAAAATCTGAATGGATGGAACTTAAAACTACTTTGTTG
AAACATCAACCTGGGCAGAAAAAAAAAAAAAAAGACATGTAAAATTTTGTTATTTCCAGTCTGTATATGAAAAAATAGGTCATCAAAAGG
AAAAAAAATAACTTTGATTAACTAGTGTTAAACAAAAAATAGGTTTACTAAATATGTTAATCTATTCTTTTAACATAAGCCTCACCTTTC
ATTTTAAAGGTTTCCATAGAATTTAGTTATTTTATCTTTCAGCCATATGCTAGTTTTTTTTTCTCTTGCCAACATGCGTAAAAAGGGAAG
CCAATTACAAGTGCAAATAATGTGGTATTCTTTTGTAACTCAAGTCTTGAAATGTTCTGTAGTGTTAAGCAAAGTCTCCTCTTGCTTGAT

>In-frame_ENST00000360047_ENST00000355849_TCGA-63-A5MY-01A_PDE4D_chr5_58476421_-_KHDRBS3_chr8_136533480_length(amino acids)=481AA_start in transcript=31_stop in transcript=1476
MLKQESWNSSVKITTCNVGDKKNINDRRSANMMHVNNFPFRRHSWICFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRS
DSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEIEKFQKGEGKDEEKY
IDVVINKNMKLGQKVLIPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRKSGEAKYFHLNDDLHVLIEVFA
PPAEAYARMGHALEEIKKFLIPDYNDEIRQAQLQELTYLNGGSENADVPVVRGKPTLRTRGVPAPAITRGRGGVTARPVGVVVPRGTPTP
RGVLSTRGPVSRGRGLLTPRARGVPPTGYRPPPPPPTQETYGEYDYDDGYGTAYDEQSYDSYDNSYSTPAQSGADYYDYGHGLSEETYDS

--------------------------------------------------------------
>In-frame_ENST00000360047_ENST00000520981_TCGA-63-A5MY-01A_PDE4D_chr5_58476421_-_KHDRBS3_chr8_136533480_length(transcript)=1403nt_BP=524nt
CAATACTTGTTGCAATAATTGCCCACGATAGCTGCTCAAACAAGAGAGTTGGAATTCATCTGTAAAAATCACTACATGTAACGTAGGAGA
CAAGAAAAATATTAATGACAGAAGATCTGCGAACATGATGCACGTGAATAATTTTCCCTTTAGAAGGCATTCCTGGATATGTTTTGATGT
GGACAATGGCACATCTGCGGGACGGAGTCCCTTGGATCCCATGACCAGCCCAGGATCCGGGCTAATTCTCCAAGCAAATTTTGTCCACAG
TCAACGACGGGAGTCCTTCCTGTATCGATCCGACAGCGATTATGACCTCTCTCCAAAGTCTATGTCCCGGAACTCCTCCATTGCCAGTGA
TATACACGGAGATGACTTGATTGTGACTCCATTTGCTCAGGTCTTGGCCAGTCTGCGAACTGTACGAAACAACTTTGCTGCATTAACTAA
TTTGCAAGATCGAGCACCTAGCAAAAGATCACCCATGTGCAACCAACCATCCATCAACAAAGCCACCATAACAGAAATAGAAAAGTTTCA
AAAAGGAGAAGGCAAGGATGAAGAAAAGTACATCGATGTGGTGATTAATAAGAACATGAAGCTGGGACAGAAAGTGTTAATTCCCGTAAA
ACAGTTCCCTAAGGACTATGATGATGGATATGGCACTGCTTATGATGAACAGAGTTATGATTCCTATGATAACAGCTATAGCACCCCAGC
CCAAAGTGGTGCTGATTACTATGATTACGGACATGGACTCAGTGAGGAGACTTATGATTCCTACGGGCAAGAAGAGTGGACTAACTCAAG
ACACAAGGCACCTTCAGCGAGGACAGCAAAGGGCGTCTACAGAGACCAGCCATATGGCAGATACTGATTGTACTGTCTGATGTTGTGAAA
TAGCCAATCTCCACCAGTCCTGTATACTGTTCAAAGTAATTTTTTTCTATGAACAATCCCTTTTTAAATAAATCAGAATGCTTAAAATCT
GAATGGATGGAACTTAAAACTACTTTGTTGAAACATCAACCTGGGCAGAAAAAAAAAAAAAAAGACATGTAAAATTTTGTTATTTCCAGT
CTGTATATGAAAAAATAGGTCATCAAAAGGAAAAAAAATAACTTTGATTAACTAGTGTTAAACAAAAAATAGGTTTACTAAATATGTTAA
TCTATTCTTTTAACATAAGCCTCACCTTTCATTTTAAAGGTTTCCATAGAATTTAGTTATTTTATCTTTCAGCCATATGCTAGTTTTTTT
TTCTCTTGCCAACATGCGTAAAAAGGGAAGCCAATTACAAGTGCAAATAATGTGGTATTCTTTTGTAACTCAAGTCTTGAAATGTTCTGT

>In-frame_ENST00000360047_ENST00000520981_TCGA-63-A5MY-01A_PDE4D_chr5_58476421_-_KHDRBS3_chr8_136533480_length(amino acids)=281AA_start in transcript=31_stop in transcript=876
MLKQESWNSSVKITTCNVGDKKNINDRRSANMMHVNNFPFRRHSWICFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRS
DSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEIEKFQKGEGKDEEKY
IDVVINKNMKLGQKVLIPVKQFPKDYDDGYGTAYDEQSYDSYDNSYSTPAQSGADYYDYGHGLSEETYDSYGQEEWTNSRHKAPSARTAK

--------------------------------------------------------------
>In-frame_ENST00000507116_ENST00000355849_TCGA-63-A5MY-01A_PDE4D_chr5_58476421_-_KHDRBS3_chr8_136533480_length(transcript)=2231nt_BP=752nt
AGAGAGACTGAGGCAGGCGACTGAATGCACTAACAGCAGCAGGCTCAGACCTGCTTCCCTGGACATTTCCGGGACCGTGAGCGAGGGAAC
CACGTTGCCCTGGATTCTTGCCAGCTGTACAAAGTTGACCAGGAAAATGGCTCAGCAGACAAGCCCGGACACTTTAACAGTACCTGAAGT
GGATAATCCGCATTGTCCAAACCCGTGGCTGAACGAAGACCTTGTGAAATCCTTGCGAGAAAACCTGTTGCAGCATGAGAAGTCCAAGAC
AGCGAGGAAATCGGTTTCTCCCAAGCTCTCTCCAGTGATCTCTCCGAGAAATTCCCCCAGGCTTCTGCGCAGAATGCTTCTCAGCAGCAA
CATCCCCAAACAGCGGCGTTTCACGGTGGCACATACATGTTTTGATGTGGACAATGGCACATCTGCGGGACGGAGTCCCTTGGATCCCAT
GACCAGCCCAGGATCCGGGCTAATTCTCCAAGCAAATTTTGTCCACAGTCAACGACGGGAGTCCTTCCTGTATCGATCCGACAGCGATTA
TGACCTCTCTCCAAAGTCTATGTCCCGGAACTCCTCCATTGCCAGTGATATACACGGAGATGACTTGATTGTGACTCCATTTGCTCAGGT
CTTGGCCAGTCTGCGAACTGTACGAAACAACTTTGCTGCATTAACTAATTTGCAAGATCGAGCACCTAGCAAAAGATCACCCATGTGCAA
CCAACCATCCATCAACAAAGCCACCATAACAGAAATAGAAAAGTTTCAAAAAGGAGAAGGCAAGGATGAAGAAAAGTACATCGATGTGGT
GATTAATAAGAACATGAAGCTGGGACAGAAAGTGTTAATTCCCGTAAAACAGTTCCCTAAGTTCAACTTTGTGGGGAAACTTTTGGGTCC
ACGTGGCAATTCTCTGAAGCGTTTACAAGAAGAAACCTTGACAAAAATGTCCATCCTTGGGAAAGGTTCCATGAGAGACAAGGCCAAGGA
AGAAGAGTTGAGGAAAAGTGGAGAAGCGAAGTACTTCCATCTCAATGATGATCTCCATGTTCTCATTGAAGTGTTTGCCCCACCTGCAGA
AGCTTATGCCAGGATGGGACATGCTTTGGAAGAAATCAAAAAGTTCCTCATCCCTGATTATAATGATGAGATCAGGCAAGCACAGCTCCA
GGAGTTAACATATTTGAATGGTGGTTCAGAAAATGCAGATGTTCCAGTGGTTCGAGGGAAACCCACCTTGCGTACAAGAGGTGTACCAGC
CCCAGCAATAACCAGGGGAAGGGGAGGAGTTACAGCCCGGCCAGTTGGAGTTGTAGTACCACGAGGGACGCCAACTCCCAGAGGAGTCCT
GTCCACCCGAGGGCCAGTGAGTCGGGGAAGAGGACTTCTCACTCCCAGAGCAAGAGGAGTCCCCCCAACTGGGTACAGACCTCCACCGCC
ACCCCCGACACAAGAGACTTATGGAGAATATGACTATGATGATGGATATGGCACTGCTTATGATGAACAGAGTTATGATTCCTATGATAA
CAGCTATAGCACCCCAGCCCAAAGTGGTGCTGATTACTATGATTACGGACATGGACTCAGTGAGGAGACTTATGATTCCTACGGGCAAGA
AGAGTGGACTAACTCAAGACACAAGGCACCTTCAGCGAGGACAGCAAAGGGCGTCTACAGAGACCAGCCATATGGCAGATACTGATTGTA
CTGTCTGATGTTGTGAAATAGCCAATCTCCACCAGTCCTGTATACTGTTCAAAGTAATTTTTTTCTATGAACAATCCCTTTTTAAATAAA
TCAGAATGCTTAAAATCTGAATGGATGGAACTTAAAACTACTTTGTTGAAACATCAACCTGGGCAGAAAAAAAAAAAAAAAGACATGTAA
AATTTTGTTATTTCCAGTCTGTATATGAAAAAATAGGTCATCAAAAGGAAAAAAAATAACTTTGATTAACTAGTGTTAAACAAAAAATAG
GTTTACTAAATATGTTAATCTATTCTTTTAACATAAGCCTCACCTTTCATTTTAAAGGTTTCCATAGAATTTAGTTATTTTATCTTTCAG
CCATATGCTAGTTTTTTTTTCTCTTGCCAACATGCGTAAAAAGGGAAGCCAATTACAAGTGCAAATAATGTGGTATTCTTTTGTAACTCA

>In-frame_ENST00000507116_ENST00000355849_TCGA-63-A5MY-01A_PDE4D_chr5_58476421_-_KHDRBS3_chr8_136533480_length(amino acids)=565AA_start in transcript=7_stop in transcript=1704
MRQATECTNSSRLRPASLDISGTVSEGTTLPWILASCTKLTRKMAQQTSPDTLTVPEVDNPHCPNPWLNEDLVKSLRENLLQHEKSKTAR
KSVSPKLSPVISPRNSPRLLRRMLLSSNIPKQRRFTVAHTCFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDL
SPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEIEKFQKGEGKDEEKYIDVVIN
KNMKLGQKVLIPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRKSGEAKYFHLNDDLHVLIEVFAPPAEAY
ARMGHALEEIKKFLIPDYNDEIRQAQLQELTYLNGGSENADVPVVRGKPTLRTRGVPAPAITRGRGGVTARPVGVVVPRGTPTPRGVLST
RGPVSRGRGLLTPRARGVPPTGYRPPPPPPTQETYGEYDYDDGYGTAYDEQSYDSYDNSYSTPAQSGADYYDYGHGLSEETYDSYGQEEW

--------------------------------------------------------------
>In-frame_ENST00000507116_ENST00000520981_TCGA-63-A5MY-01A_PDE4D_chr5_58476421_-_KHDRBS3_chr8_136533480_length(transcript)=1631nt_BP=752nt
AGAGAGACTGAGGCAGGCGACTGAATGCACTAACAGCAGCAGGCTCAGACCTGCTTCCCTGGACATTTCCGGGACCGTGAGCGAGGGAAC
CACGTTGCCCTGGATTCTTGCCAGCTGTACAAAGTTGACCAGGAAAATGGCTCAGCAGACAAGCCCGGACACTTTAACAGTACCTGAAGT
GGATAATCCGCATTGTCCAAACCCGTGGCTGAACGAAGACCTTGTGAAATCCTTGCGAGAAAACCTGTTGCAGCATGAGAAGTCCAAGAC
AGCGAGGAAATCGGTTTCTCCCAAGCTCTCTCCAGTGATCTCTCCGAGAAATTCCCCCAGGCTTCTGCGCAGAATGCTTCTCAGCAGCAA
CATCCCCAAACAGCGGCGTTTCACGGTGGCACATACATGTTTTGATGTGGACAATGGCACATCTGCGGGACGGAGTCCCTTGGATCCCAT
GACCAGCCCAGGATCCGGGCTAATTCTCCAAGCAAATTTTGTCCACAGTCAACGACGGGAGTCCTTCCTGTATCGATCCGACAGCGATTA
TGACCTCTCTCCAAAGTCTATGTCCCGGAACTCCTCCATTGCCAGTGATATACACGGAGATGACTTGATTGTGACTCCATTTGCTCAGGT
CTTGGCCAGTCTGCGAACTGTACGAAACAACTTTGCTGCATTAACTAATTTGCAAGATCGAGCACCTAGCAAAAGATCACCCATGTGCAA
CCAACCATCCATCAACAAAGCCACCATAACAGAAATAGAAAAGTTTCAAAAAGGAGAAGGCAAGGATGAAGAAAAGTACATCGATGTGGT
GATTAATAAGAACATGAAGCTGGGACAGAAAGTGTTAATTCCCGTAAAACAGTTCCCTAAGGACTATGATGATGGATATGGCACTGCTTA
TGATGAACAGAGTTATGATTCCTATGATAACAGCTATAGCACCCCAGCCCAAAGTGGTGCTGATTACTATGATTACGGACATGGACTCAG
TGAGGAGACTTATGATTCCTACGGGCAAGAAGAGTGGACTAACTCAAGACACAAGGCACCTTCAGCGAGGACAGCAAAGGGCGTCTACAG
AGACCAGCCATATGGCAGATACTGATTGTACTGTCTGATGTTGTGAAATAGCCAATCTCCACCAGTCCTGTATACTGTTCAAAGTAATTT
TTTTCTATGAACAATCCCTTTTTAAATAAATCAGAATGCTTAAAATCTGAATGGATGGAACTTAAAACTACTTTGTTGAAACATCAACCT
GGGCAGAAAAAAAAAAAAAAAGACATGTAAAATTTTGTTATTTCCAGTCTGTATATGAAAAAATAGGTCATCAAAAGGAAAAAAAATAAC
TTTGATTAACTAGTGTTAAACAAAAAATAGGTTTACTAAATATGTTAATCTATTCTTTTAACATAAGCCTCACCTTTCATTTTAAAGGTT
TCCATAGAATTTAGTTATTTTATCTTTCAGCCATATGCTAGTTTTTTTTTCTCTTGCCAACATGCGTAAAAAGGGAAGCCAATTACAAGT
GCAAATAATGTGGTATTCTTTTGTAACTCAAGTCTTGAAATGTTCTGTAGTGTTAAGCAAAGTCTCCTCTTGCTTGATACTAAATAAACT

>In-frame_ENST00000507116_ENST00000520981_TCGA-63-A5MY-01A_PDE4D_chr5_58476421_-_KHDRBS3_chr8_136533480_length(amino acids)=365AA_start in transcript=7_stop in transcript=1104
MRQATECTNSSRLRPASLDISGTVSEGTTLPWILASCTKLTRKMAQQTSPDTLTVPEVDNPHCPNPWLNEDLVKSLRENLLQHEKSKTAR
KSVSPKLSPVISPRNSPRLLRRMLLSSNIPKQRRFTVAHTCFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDL
SPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEIEKFQKGEGKDEEKYIDVVIN
KNMKLGQKVLIPVKQFPKDYDDGYGTAYDEQSYDSYDNSYSTPAQSGADYYDYGHGLSEETYDSYGQEEWTNSRHKAPSARTAKGVYRDQ

--------------------------------------------------------------
>In-frame_ENST00000546160_ENST00000355849_TCGA-63-A5MY-01A_PDE4D_chr5_58476421_-_KHDRBS3_chr8_136533480_length(transcript)=2104nt_BP=625nt
ATGAAAAGAAATACCTGTGATTTGCTTTCTCGGAGCAAAAGTGCCTCTGAGGAAACACTACATTCCAGTAATGAAGAGGAAGACCCTTTC
CGCGGAATGGAACCCTATCTTGTCCGGAGACTTTCATGTCGCAATATTCAGCTTCCCCCTCTCGCCTTCAGACAGTTGGAACAAGCTGAC
TTGAAAAGTGAATCAGAGAACATTCAACGACCAACCAGCCTCCCCCTGAAGATTCTGCCGCTGATTGCTATCACTTCTGCAGAATCCAGT
GGTTTTGATGTGGACAATGGCACATCTGCGGGACGGAGTCCCTTGGATCCCATGACCAGCCCAGGATCCGGGCTAATTCTCCAAGCAAAT
TTTGTCCACAGTCAACGACGGGAGTCCTTCCTGTATCGATCCGACAGCGATTATGACCTCTCTCCAAAGTCTATGTCCCGGAACTCCTCC
ATTGCCAGTGATATACACGGAGATGACTTGATTGTGACTCCATTTGCTCAGGTCTTGGCCAGTCTGCGAACTGTACGAAACAACTTTGCT
GCATTAACTAATTTGCAAGATCGAGCACCTAGCAAAAGATCACCCATGTGCAACCAACCATCCATCAACAAAGCCACCATAACAGAAATA
GAAAAGTTTCAAAAAGGAGAAGGCAAGGATGAAGAAAAGTACATCGATGTGGTGATTAATAAGAACATGAAGCTGGGACAGAAAGTGTTA
ATTCCCGTAAAACAGTTCCCTAAGTTCAACTTTGTGGGGAAACTTTTGGGTCCACGTGGCAATTCTCTGAAGCGTTTACAAGAAGAAACC
TTGACAAAAATGTCCATCCTTGGGAAAGGTTCCATGAGAGACAAGGCCAAGGAAGAAGAGTTGAGGAAAAGTGGAGAAGCGAAGTACTTC
CATCTCAATGATGATCTCCATGTTCTCATTGAAGTGTTTGCCCCACCTGCAGAAGCTTATGCCAGGATGGGACATGCTTTGGAAGAAATC
AAAAAGTTCCTCATCCCTGATTATAATGATGAGATCAGGCAAGCACAGCTCCAGGAGTTAACATATTTGAATGGTGGTTCAGAAAATGCA
GATGTTCCAGTGGTTCGAGGGAAACCCACCTTGCGTACAAGAGGTGTACCAGCCCCAGCAATAACCAGGGGAAGGGGAGGAGTTACAGCC
CGGCCAGTTGGAGTTGTAGTACCACGAGGGACGCCAACTCCCAGAGGAGTCCTGTCCACCCGAGGGCCAGTGAGTCGGGGAAGAGGACTT
CTCACTCCCAGAGCAAGAGGAGTCCCCCCAACTGGGTACAGACCTCCACCGCCACCCCCGACACAAGAGACTTATGGAGAATATGACTAT
GATGATGGATATGGCACTGCTTATGATGAACAGAGTTATGATTCCTATGATAACAGCTATAGCACCCCAGCCCAAAGTGGTGCTGATTAC
TATGATTACGGACATGGACTCAGTGAGGAGACTTATGATTCCTACGGGCAAGAAGAGTGGACTAACTCAAGACACAAGGCACCTTCAGCG
AGGACAGCAAAGGGCGTCTACAGAGACCAGCCATATGGCAGATACTGATTGTACTGTCTGATGTTGTGAAATAGCCAATCTCCACCAGTC
CTGTATACTGTTCAAAGTAATTTTTTTCTATGAACAATCCCTTTTTAAATAAATCAGAATGCTTAAAATCTGAATGGATGGAACTTAAAA
CTACTTTGTTGAAACATCAACCTGGGCAGAAAAAAAAAAAAAAAGACATGTAAAATTTTGTTATTTCCAGTCTGTATATGAAAAAATAGG
TCATCAAAAGGAAAAAAAATAACTTTGATTAACTAGTGTTAAACAAAAAATAGGTTTACTAAATATGTTAATCTATTCTTTTAACATAAG
CCTCACCTTTCATTTTAAAGGTTTCCATAGAATTTAGTTATTTTATCTTTCAGCCATATGCTAGTTTTTTTTTCTCTTGCCAACATGCGT
AAAAAGGGAAGCCAATTACAAGTGCAAATAATGTGGTATTCTTTTGTAACTCAAGTCTTGAAATGTTCTGTAGTGTTAAGCAAAGTCTCC

>In-frame_ENST00000546160_ENST00000355849_TCGA-63-A5MY-01A_PDE4D_chr5_58476421_-_KHDRBS3_chr8_136533480_length(amino acids)=525AA_start in transcript=0_stop in transcript=1577
MKRNTCDLLSRSKSASEETLHSSNEEEDPFRGMEPYLVRRLSCRNIQLPPLAFRQLEQADLKSESENIQRPTSLPLKILPLIAITSAESS
GFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFA
ALTNLQDRAPSKRSPMCNQPSINKATITEIEKFQKGEGKDEEKYIDVVINKNMKLGQKVLIPVKQFPKFNFVGKLLGPRGNSLKRLQEET
LTKMSILGKGSMRDKAKEEELRKSGEAKYFHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFLIPDYNDEIRQAQLQELTYLNGGSENA
DVPVVRGKPTLRTRGVPAPAITRGRGGVTARPVGVVVPRGTPTPRGVLSTRGPVSRGRGLLTPRARGVPPTGYRPPPPPPTQETYGEYDY

--------------------------------------------------------------
>In-frame_ENST00000546160_ENST00000520981_TCGA-63-A5MY-01A_PDE4D_chr5_58476421_-_KHDRBS3_chr8_136533480_length(transcript)=1504nt_BP=625nt
ATGAAAAGAAATACCTGTGATTTGCTTTCTCGGAGCAAAAGTGCCTCTGAGGAAACACTACATTCCAGTAATGAAGAGGAAGACCCTTTC
CGCGGAATGGAACCCTATCTTGTCCGGAGACTTTCATGTCGCAATATTCAGCTTCCCCCTCTCGCCTTCAGACAGTTGGAACAAGCTGAC
TTGAAAAGTGAATCAGAGAACATTCAACGACCAACCAGCCTCCCCCTGAAGATTCTGCCGCTGATTGCTATCACTTCTGCAGAATCCAGT
GGTTTTGATGTGGACAATGGCACATCTGCGGGACGGAGTCCCTTGGATCCCATGACCAGCCCAGGATCCGGGCTAATTCTCCAAGCAAAT
TTTGTCCACAGTCAACGACGGGAGTCCTTCCTGTATCGATCCGACAGCGATTATGACCTCTCTCCAAAGTCTATGTCCCGGAACTCCTCC
ATTGCCAGTGATATACACGGAGATGACTTGATTGTGACTCCATTTGCTCAGGTCTTGGCCAGTCTGCGAACTGTACGAAACAACTTTGCT
GCATTAACTAATTTGCAAGATCGAGCACCTAGCAAAAGATCACCCATGTGCAACCAACCATCCATCAACAAAGCCACCATAACAGAAATA
GAAAAGTTTCAAAAAGGAGAAGGCAAGGATGAAGAAAAGTACATCGATGTGGTGATTAATAAGAACATGAAGCTGGGACAGAAAGTGTTA
ATTCCCGTAAAACAGTTCCCTAAGGACTATGATGATGGATATGGCACTGCTTATGATGAACAGAGTTATGATTCCTATGATAACAGCTAT
AGCACCCCAGCCCAAAGTGGTGCTGATTACTATGATTACGGACATGGACTCAGTGAGGAGACTTATGATTCCTACGGGCAAGAAGAGTGG
ACTAACTCAAGACACAAGGCACCTTCAGCGAGGACAGCAAAGGGCGTCTACAGAGACCAGCCATATGGCAGATACTGATTGTACTGTCTG
ATGTTGTGAAATAGCCAATCTCCACCAGTCCTGTATACTGTTCAAAGTAATTTTTTTCTATGAACAATCCCTTTTTAAATAAATCAGAAT
GCTTAAAATCTGAATGGATGGAACTTAAAACTACTTTGTTGAAACATCAACCTGGGCAGAAAAAAAAAAAAAAAGACATGTAAAATTTTG
TTATTTCCAGTCTGTATATGAAAAAATAGGTCATCAAAAGGAAAAAAAATAACTTTGATTAACTAGTGTTAAACAAAAAATAGGTTTACT
AAATATGTTAATCTATTCTTTTAACATAAGCCTCACCTTTCATTTTAAAGGTTTCCATAGAATTTAGTTATTTTATCTTTCAGCCATATG
CTAGTTTTTTTTTCTCTTGCCAACATGCGTAAAAAGGGAAGCCAATTACAAGTGCAAATAATGTGGTATTCTTTTGTAACTCAAGTCTTG

>In-frame_ENST00000546160_ENST00000520981_TCGA-63-A5MY-01A_PDE4D_chr5_58476421_-_KHDRBS3_chr8_136533480_length(amino acids)=325AA_start in transcript=0_stop in transcript=977
MKRNTCDLLSRSKSASEETLHSSNEEEDPFRGMEPYLVRRLSCRNIQLPPLAFRQLEQADLKSESENIQRPTSLPLKILPLIAITSAESS
GFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFA
ALTNLQDRAPSKRSPMCNQPSINKATITEIEKFQKGEGKDEEKYIDVVINKNMKLGQKVLIPVKQFPKDYDDGYGTAYDEQSYDSYDNSY

--------------------------------------------------------------
>In-frame_ENST00000502575_ENST00000355849_TCGA-63-A5MY-01A_PDE4D_chr5_58476421_-_KHDRBS3_chr8_136533480_length(transcript)=2222nt_BP=743nt
GAGGCAGGCGACTGAATGCACTAACAGCAGCAGGCTCAGACCTGCTTCCCTGGACATTTCCGGGACCGTGAGCGAGGGAACCACGTTGCC
CTGGATTCTTGCCAGCTGTACAAAGTTGACCAGGAAAATGGCTCAGCAGACAAGCCCGGACACTTTAACAGTACCTGAAGTGGATAATCC
GCATTGTCCAAACCCGTGGCTGAACGAAGACCTTGTGAAATCCTTGCGAGAAAACCTGTTGCAGCATGAGAAGTCCAAGACAGCGAGGAA
ATCGGTTTCTCCCAAGCTCTCTCCAGTGATCTCTCCGAGAAATTCCCCCAGGCTTCTGCGCAGAATGCTTCTCAGCAGCAACATCCCCAA
ACAGCGGCGTTTCACGGTGGCACATACATGTTTTGATGTGGACAATGGCACATCTGCGGGACGGAGTCCCTTGGATCCCATGACCAGCCC
AGGATCCGGGCTAATTCTCCAAGCAAATTTTGTCCACAGTCAACGACGGGAGTCCTTCCTGTATCGATCCGACAGCGATTATGACCTCTC
TCCAAAGTCTATGTCCCGGAACTCCTCCATTGCCAGTGATATACACGGAGATGACTTGATTGTGACTCCATTTGCTCAGGTCTTGGCCAG
TCTGCGAACTGTACGAAACAACTTTGCTGCATTAACTAATTTGCAAGATCGAGCACCTAGCAAAAGATCACCCATGTGCAACCAACCATC
CATCAACAAAGCCACCATAACAGAAATAGAAAAGTTTCAAAAAGGAGAAGGCAAGGATGAAGAAAAGTACATCGATGTGGTGATTAATAA
GAACATGAAGCTGGGACAGAAAGTGTTAATTCCCGTAAAACAGTTCCCTAAGTTCAACTTTGTGGGGAAACTTTTGGGTCCACGTGGCAA
TTCTCTGAAGCGTTTACAAGAAGAAACCTTGACAAAAATGTCCATCCTTGGGAAAGGTTCCATGAGAGACAAGGCCAAGGAAGAAGAGTT
GAGGAAAAGTGGAGAAGCGAAGTACTTCCATCTCAATGATGATCTCCATGTTCTCATTGAAGTGTTTGCCCCACCTGCAGAAGCTTATGC
CAGGATGGGACATGCTTTGGAAGAAATCAAAAAGTTCCTCATCCCTGATTATAATGATGAGATCAGGCAAGCACAGCTCCAGGAGTTAAC
ATATTTGAATGGTGGTTCAGAAAATGCAGATGTTCCAGTGGTTCGAGGGAAACCCACCTTGCGTACAAGAGGTGTACCAGCCCCAGCAAT
AACCAGGGGAAGGGGAGGAGTTACAGCCCGGCCAGTTGGAGTTGTAGTACCACGAGGGACGCCAACTCCCAGAGGAGTCCTGTCCACCCG
AGGGCCAGTGAGTCGGGGAAGAGGACTTCTCACTCCCAGAGCAAGAGGAGTCCCCCCAACTGGGTACAGACCTCCACCGCCACCCCCGAC
ACAAGAGACTTATGGAGAATATGACTATGATGATGGATATGGCACTGCTTATGATGAACAGAGTTATGATTCCTATGATAACAGCTATAG
CACCCCAGCCCAAAGTGGTGCTGATTACTATGATTACGGACATGGACTCAGTGAGGAGACTTATGATTCCTACGGGCAAGAAGAGTGGAC
TAACTCAAGACACAAGGCACCTTCAGCGAGGACAGCAAAGGGCGTCTACAGAGACCAGCCATATGGCAGATACTGATTGTACTGTCTGAT
GTTGTGAAATAGCCAATCTCCACCAGTCCTGTATACTGTTCAAAGTAATTTTTTTCTATGAACAATCCCTTTTTAAATAAATCAGAATGC
TTAAAATCTGAATGGATGGAACTTAAAACTACTTTGTTGAAACATCAACCTGGGCAGAAAAAAAAAAAAAAAGACATGTAAAATTTTGTT
ATTTCCAGTCTGTATATGAAAAAATAGGTCATCAAAAGGAAAAAAAATAACTTTGATTAACTAGTGTTAAACAAAAAATAGGTTTACTAA
ATATGTTAATCTATTCTTTTAACATAAGCCTCACCTTTCATTTTAAAGGTTTCCATAGAATTTAGTTATTTTATCTTTCAGCCATATGCT
AGTTTTTTTTTCTCTTGCCAACATGCGTAAAAAGGGAAGCCAATTACAAGTGCAAATAATGTGGTATTCTTTTGTAACTCAAGTCTTGAA

>In-frame_ENST00000502575_ENST00000355849_TCGA-63-A5MY-01A_PDE4D_chr5_58476421_-_KHDRBS3_chr8_136533480_length(amino acids)=548AA_start in transcript=49_stop in transcript=1695
MDISGTVSEGTTLPWILASCTKLTRKMAQQTSPDTLTVPEVDNPHCPNPWLNEDLVKSLRENLLQHEKSKTARKSVSPKLSPVISPRNSP
RLLRRMLLSSNIPKQRRFTVAHTCFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHG
DDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEIEKFQKGEGKDEEKYIDVVINKNMKLGQKVLIPVKQFP
KFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRKSGEAKYFHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFLIPD
YNDEIRQAQLQELTYLNGGSENADVPVVRGKPTLRTRGVPAPAITRGRGGVTARPVGVVVPRGTPTPRGVLSTRGPVSRGRGLLTPRARG
VPPTGYRPPPPPPTQETYGEYDYDDGYGTAYDEQSYDSYDNSYSTPAQSGADYYDYGHGLSEETYDSYGQEEWTNSRHKAPSARTAKGVY

--------------------------------------------------------------
>In-frame_ENST00000502575_ENST00000520981_TCGA-63-A5MY-01A_PDE4D_chr5_58476421_-_KHDRBS3_chr8_136533480_length(transcript)=1622nt_BP=743nt
GAGGCAGGCGACTGAATGCACTAACAGCAGCAGGCTCAGACCTGCTTCCCTGGACATTTCCGGGACCGTGAGCGAGGGAACCACGTTGCC
CTGGATTCTTGCCAGCTGTACAAAGTTGACCAGGAAAATGGCTCAGCAGACAAGCCCGGACACTTTAACAGTACCTGAAGTGGATAATCC
GCATTGTCCAAACCCGTGGCTGAACGAAGACCTTGTGAAATCCTTGCGAGAAAACCTGTTGCAGCATGAGAAGTCCAAGACAGCGAGGAA
ATCGGTTTCTCCCAAGCTCTCTCCAGTGATCTCTCCGAGAAATTCCCCCAGGCTTCTGCGCAGAATGCTTCTCAGCAGCAACATCCCCAA
ACAGCGGCGTTTCACGGTGGCACATACATGTTTTGATGTGGACAATGGCACATCTGCGGGACGGAGTCCCTTGGATCCCATGACCAGCCC
AGGATCCGGGCTAATTCTCCAAGCAAATTTTGTCCACAGTCAACGACGGGAGTCCTTCCTGTATCGATCCGACAGCGATTATGACCTCTC
TCCAAAGTCTATGTCCCGGAACTCCTCCATTGCCAGTGATATACACGGAGATGACTTGATTGTGACTCCATTTGCTCAGGTCTTGGCCAG
TCTGCGAACTGTACGAAACAACTTTGCTGCATTAACTAATTTGCAAGATCGAGCACCTAGCAAAAGATCACCCATGTGCAACCAACCATC
CATCAACAAAGCCACCATAACAGAAATAGAAAAGTTTCAAAAAGGAGAAGGCAAGGATGAAGAAAAGTACATCGATGTGGTGATTAATAA
GAACATGAAGCTGGGACAGAAAGTGTTAATTCCCGTAAAACAGTTCCCTAAGGACTATGATGATGGATATGGCACTGCTTATGATGAACA
GAGTTATGATTCCTATGATAACAGCTATAGCACCCCAGCCCAAAGTGGTGCTGATTACTATGATTACGGACATGGACTCAGTGAGGAGAC
TTATGATTCCTACGGGCAAGAAGAGTGGACTAACTCAAGACACAAGGCACCTTCAGCGAGGACAGCAAAGGGCGTCTACAGAGACCAGCC
ATATGGCAGATACTGATTGTACTGTCTGATGTTGTGAAATAGCCAATCTCCACCAGTCCTGTATACTGTTCAAAGTAATTTTTTTCTATG
AACAATCCCTTTTTAAATAAATCAGAATGCTTAAAATCTGAATGGATGGAACTTAAAACTACTTTGTTGAAACATCAACCTGGGCAGAAA
AAAAAAAAAAAAGACATGTAAAATTTTGTTATTTCCAGTCTGTATATGAAAAAATAGGTCATCAAAAGGAAAAAAAATAACTTTGATTAA
CTAGTGTTAAACAAAAAATAGGTTTACTAAATATGTTAATCTATTCTTTTAACATAAGCCTCACCTTTCATTTTAAAGGTTTCCATAGAA
TTTAGTTATTTTATCTTTCAGCCATATGCTAGTTTTTTTTTCTCTTGCCAACATGCGTAAAAAGGGAAGCCAATTACAAGTGCAAATAAT
GTGGTATTCTTTTGTAACTCAAGTCTTGAAATGTTCTGTAGTGTTAAGCAAAGTCTCCTCTTGCTTGATACTAAATAAACTTTTGAAAGA

>In-frame_ENST00000502575_ENST00000520981_TCGA-63-A5MY-01A_PDE4D_chr5_58476421_-_KHDRBS3_chr8_136533480_length(amino acids)=348AA_start in transcript=49_stop in transcript=1095
MDISGTVSEGTTLPWILASCTKLTRKMAQQTSPDTLTVPEVDNPHCPNPWLNEDLVKSLRENLLQHEKSKTARKSVSPKLSPVISPRNSP
RLLRRMLLSSNIPKQRRFTVAHTCFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHG
DDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEIEKFQKGEGKDEEKYIDVVINKNMKLGQKVLIPVKQFP

--------------------------------------------------------------
>In-frame_ENST00000503258_ENST00000355849_TCGA-63-A5MY-01A_PDE4D_chr5_58476421_-_KHDRBS3_chr8_136533480_length(transcript)=2614nt_BP=1135nt
TTCTCACTGCCCTGCGGTGTTTTGAACTGCCTTCTTACAGACGTCATACAGCCCTTGAGGAATAGTTTCTGCCTGGTGAGATTGAATGAT
AGTTCTCATTCACAAAACCCTGGATTCTAAGCAGGGACACACAGAAATTACTTTCGCAGGTAAATCAGCCCACCCAGCCAAAGTGTGGAG
AGATTTGTTCCTTGGCTGACTTCTTTGCTCCACGGAGAGGAGTGTTTTCCTGTGCTTGCCCTGAAATGGAACTTCCTTGACAGCTCTCCC
GTGTTACAGTACCTCCCGGTCATTTTCTTTTTCTCTCTCTCTACCTGCGCTCTTCGAGTGTCAGAAACCTTTAAAGCTGTTACTATGGAA
TTGCAAAAAAGAGATCAAGTGACTCTTTCACTATGCTGGTTTCCCTTGTGACCCAGATGAAGAATCAATTCAGAATTCAGTTCCTCCCTT
GGCATTGCAAGACACAGAAGAAACTGTCACTTCCTAACAGCCTAGTACTGGAGTAAATTCAGTATGAAGGAAGAAAGCGCTCCTGCGTGT
TAGAACCTTGCCCATGAGCTGGACCGAGGACAGGAGATGGACTCCAGGAAAATTGGATTTCTTCAAGCAGCCTCCCTTGGAAATGGAATA
TCTTTAAAATCTTCTTTGCAGAAAGACAGTTAGAATGTATTAATCAGAATAGTTGAAGACTTATTTTCCTTTTTATTTTTTTTCAAAATG
AGCATTATTATGAAGCCAAGATCCCGATCTACAAGTTCCCTAAGGACTGCAGAGGCAGTTTGTTTTGATGTGGACAATGGCACATCTGCG
GGACGGAGTCCCTTGGATCCCATGACCAGCCCAGGATCCGGGCTAATTCTCCAAGCAAATTTTGTCCACAGTCAACGACGGGAGTCCTTC
CTGTATCGATCCGACAGCGATTATGACCTCTCTCCAAAGTCTATGTCCCGGAACTCCTCCATTGCCAGTGATATACACGGAGATGACTTG
ATTGTGACTCCATTTGCTCAGGTCTTGGCCAGTCTGCGAACTGTACGAAACAACTTTGCTGCATTAACTAATTTGCAAGATCGAGCACCT
AGCAAAAGATCACCCATGTGCAACCAACCATCCATCAACAAAGCCACCATAACAGAAATAGAAAAGTTTCAAAAAGGAGAAGGCAAGGAT
GAAGAAAAGTACATCGATGTGGTGATTAATAAGAACATGAAGCTGGGACAGAAAGTGTTAATTCCCGTAAAACAGTTCCCTAAGTTCAAC
TTTGTGGGGAAACTTTTGGGTCCACGTGGCAATTCTCTGAAGCGTTTACAAGAAGAAACCTTGACAAAAATGTCCATCCTTGGGAAAGGT
TCCATGAGAGACAAGGCCAAGGAAGAAGAGTTGAGGAAAAGTGGAGAAGCGAAGTACTTCCATCTCAATGATGATCTCCATGTTCTCATT
GAAGTGTTTGCCCCACCTGCAGAAGCTTATGCCAGGATGGGACATGCTTTGGAAGAAATCAAAAAGTTCCTCATCCCTGATTATAATGAT
GAGATCAGGCAAGCACAGCTCCAGGAGTTAACATATTTGAATGGTGGTTCAGAAAATGCAGATGTTCCAGTGGTTCGAGGGAAACCCACC
TTGCGTACAAGAGGTGTACCAGCCCCAGCAATAACCAGGGGAAGGGGAGGAGTTACAGCCCGGCCAGTTGGAGTTGTAGTACCACGAGGG
ACGCCAACTCCCAGAGGAGTCCTGTCCACCCGAGGGCCAGTGAGTCGGGGAAGAGGACTTCTCACTCCCAGAGCAAGAGGAGTCCCCCCA
ACTGGGTACAGACCTCCACCGCCACCCCCGACACAAGAGACTTATGGAGAATATGACTATGATGATGGATATGGCACTGCTTATGATGAA
CAGAGTTATGATTCCTATGATAACAGCTATAGCACCCCAGCCCAAAGTGGTGCTGATTACTATGATTACGGACATGGACTCAGTGAGGAG
ACTTATGATTCCTACGGGCAAGAAGAGTGGACTAACTCAAGACACAAGGCACCTTCAGCGAGGACAGCAAAGGGCGTCTACAGAGACCAG
CCATATGGCAGATACTGATTGTACTGTCTGATGTTGTGAAATAGCCAATCTCCACCAGTCCTGTATACTGTTCAAAGTAATTTTTTTCTA
TGAACAATCCCTTTTTAAATAAATCAGAATGCTTAAAATCTGAATGGATGGAACTTAAAACTACTTTGTTGAAACATCAACCTGGGCAGA
AAAAAAAAAAAAAAGACATGTAAAATTTTGTTATTTCCAGTCTGTATATGAAAAAATAGGTCATCAAAAGGAAAAAAAATAACTTTGATT
AACTAGTGTTAAACAAAAAATAGGTTTACTAAATATGTTAATCTATTCTTTTAACATAAGCCTCACCTTTCATTTTAAAGGTTTCCATAG
AATTTAGTTATTTTATCTTTCAGCCATATGCTAGTTTTTTTTTCTCTTGCCAACATGCGTAAAAAGGGAAGCCAATTACAAGTGCAAATA
ATGTGGTATTCTTTTGTAACTCAAGTCTTGAAATGTTCTGTAGTGTTAAGCAAAGTCTCCTCTTGCTTGATACTAAATAAACTTTTGAAA

>In-frame_ENST00000503258_ENST00000355849_TCGA-63-A5MY-01A_PDE4D_chr5_58476421_-_KHDRBS3_chr8_136533480_length(amino acids)=456AA_start in transcript=717_stop in transcript=2087
MSIIMKPRSRSTSSLRTAEAVCFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDD
LIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEIEKFQKGEGKDEEKYIDVVINKNMKLGQKVLIPVKQFPKF
NFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRKSGEAKYFHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFLIPDYN
DEIRQAQLQELTYLNGGSENADVPVVRGKPTLRTRGVPAPAITRGRGGVTARPVGVVVPRGTPTPRGVLSTRGPVSRGRGLLTPRARGVP
PTGYRPPPPPPTQETYGEYDYDDGYGTAYDEQSYDSYDNSYSTPAQSGADYYDYGHGLSEETYDSYGQEEWTNSRHKAPSARTAKGVYRD

--------------------------------------------------------------
>In-frame_ENST00000503258_ENST00000520981_TCGA-63-A5MY-01A_PDE4D_chr5_58476421_-_KHDRBS3_chr8_136533480_length(transcript)=2014nt_BP=1135nt
TTCTCACTGCCCTGCGGTGTTTTGAACTGCCTTCTTACAGACGTCATACAGCCCTTGAGGAATAGTTTCTGCCTGGTGAGATTGAATGAT
AGTTCTCATTCACAAAACCCTGGATTCTAAGCAGGGACACACAGAAATTACTTTCGCAGGTAAATCAGCCCACCCAGCCAAAGTGTGGAG
AGATTTGTTCCTTGGCTGACTTCTTTGCTCCACGGAGAGGAGTGTTTTCCTGTGCTTGCCCTGAAATGGAACTTCCTTGACAGCTCTCCC
GTGTTACAGTACCTCCCGGTCATTTTCTTTTTCTCTCTCTCTACCTGCGCTCTTCGAGTGTCAGAAACCTTTAAAGCTGTTACTATGGAA
TTGCAAAAAAGAGATCAAGTGACTCTTTCACTATGCTGGTTTCCCTTGTGACCCAGATGAAGAATCAATTCAGAATTCAGTTCCTCCCTT
GGCATTGCAAGACACAGAAGAAACTGTCACTTCCTAACAGCCTAGTACTGGAGTAAATTCAGTATGAAGGAAGAAAGCGCTCCTGCGTGT
TAGAACCTTGCCCATGAGCTGGACCGAGGACAGGAGATGGACTCCAGGAAAATTGGATTTCTTCAAGCAGCCTCCCTTGGAAATGGAATA
TCTTTAAAATCTTCTTTGCAGAAAGACAGTTAGAATGTATTAATCAGAATAGTTGAAGACTTATTTTCCTTTTTATTTTTTTTCAAAATG
AGCATTATTATGAAGCCAAGATCCCGATCTACAAGTTCCCTAAGGACTGCAGAGGCAGTTTGTTTTGATGTGGACAATGGCACATCTGCG
GGACGGAGTCCCTTGGATCCCATGACCAGCCCAGGATCCGGGCTAATTCTCCAAGCAAATTTTGTCCACAGTCAACGACGGGAGTCCTTC
CTGTATCGATCCGACAGCGATTATGACCTCTCTCCAAAGTCTATGTCCCGGAACTCCTCCATTGCCAGTGATATACACGGAGATGACTTG
ATTGTGACTCCATTTGCTCAGGTCTTGGCCAGTCTGCGAACTGTACGAAACAACTTTGCTGCATTAACTAATTTGCAAGATCGAGCACCT
AGCAAAAGATCACCCATGTGCAACCAACCATCCATCAACAAAGCCACCATAACAGAAATAGAAAAGTTTCAAAAAGGAGAAGGCAAGGAT
GAAGAAAAGTACATCGATGTGGTGATTAATAAGAACATGAAGCTGGGACAGAAAGTGTTAATTCCCGTAAAACAGTTCCCTAAGGACTAT
GATGATGGATATGGCACTGCTTATGATGAACAGAGTTATGATTCCTATGATAACAGCTATAGCACCCCAGCCCAAAGTGGTGCTGATTAC
TATGATTACGGACATGGACTCAGTGAGGAGACTTATGATTCCTACGGGCAAGAAGAGTGGACTAACTCAAGACACAAGGCACCTTCAGCG
AGGACAGCAAAGGGCGTCTACAGAGACCAGCCATATGGCAGATACTGATTGTACTGTCTGATGTTGTGAAATAGCCAATCTCCACCAGTC
CTGTATACTGTTCAAAGTAATTTTTTTCTATGAACAATCCCTTTTTAAATAAATCAGAATGCTTAAAATCTGAATGGATGGAACTTAAAA
CTACTTTGTTGAAACATCAACCTGGGCAGAAAAAAAAAAAAAAAGACATGTAAAATTTTGTTATTTCCAGTCTGTATATGAAAAAATAGG
TCATCAAAAGGAAAAAAAATAACTTTGATTAACTAGTGTTAAACAAAAAATAGGTTTACTAAATATGTTAATCTATTCTTTTAACATAAG
CCTCACCTTTCATTTTAAAGGTTTCCATAGAATTTAGTTATTTTATCTTTCAGCCATATGCTAGTTTTTTTTTCTCTTGCCAACATGCGT
AAAAAGGGAAGCCAATTACAAGTGCAAATAATGTGGTATTCTTTTGTAACTCAAGTCTTGAAATGTTCTGTAGTGTTAAGCAAAGTCTCC

>In-frame_ENST00000503258_ENST00000520981_TCGA-63-A5MY-01A_PDE4D_chr5_58476421_-_KHDRBS3_chr8_136533480_length(amino acids)=256AA_start in transcript=717_stop in transcript=1487
MSIIMKPRSRSTSSLRTAEAVCFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDD
LIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEIEKFQKGEGKDEEKYIDVVINKNMKLGQKVLIPVKQFPKD

--------------------------------------------------------------
>In-frame_ENST00000405755_ENST00000355849_TCGA-63-A5MY-01A_PDE4D_chr5_58476421_-_KHDRBS3_chr8_136533480_length(transcript)=2050nt_BP=571nt
ACTGCACAAAGGAAATGCCCTCACTCAGCTACAAGTGCCTCCTGCTCCGTGCGGGGCCTCAGGGCCCCAGAGCCCCGCACCAGCTCTGAC
TTCTCGTGGTTCCTGGGGATCTTGGCATCGTCCTTAAAAATGGCTTTTGTTTGGGATCCTCTGGGAGCCACGGTGCCAGGACCATCTACA
AGAGCCAAATCAAGATTGCGTTTCTCAAAGTCCTACAGTTTTGATGTGGACAATGGCACATCTGCGGGACGGAGTCCCTTGGATCCCATG
ACCAGCCCAGGATCCGGGCTAATTCTCCAAGCAAATTTTGTCCACAGTCAACGACGGGAGTCCTTCCTGTATCGATCCGACAGCGATTAT
GACCTCTCTCCAAAGTCTATGTCCCGGAACTCCTCCATTGCCAGTGATATACACGGAGATGACTTGATTGTGACTCCATTTGCTCAGGTC
TTGGCCAGTCTGCGAACTGTACGAAACAACTTTGCTGCATTAACTAATTTGCAAGATCGAGCACCTAGCAAAAGATCACCCATGTGCAAC
CAACCATCCATCAACAAAGCCACCATAACAGAAATAGAAAAGTTTCAAAAAGGAGAAGGCAAGGATGAAGAAAAGTACATCGATGTGGTG
ATTAATAAGAACATGAAGCTGGGACAGAAAGTGTTAATTCCCGTAAAACAGTTCCCTAAGTTCAACTTTGTGGGGAAACTTTTGGGTCCA
CGTGGCAATTCTCTGAAGCGTTTACAAGAAGAAACCTTGACAAAAATGTCCATCCTTGGGAAAGGTTCCATGAGAGACAAGGCCAAGGAA
GAAGAGTTGAGGAAAAGTGGAGAAGCGAAGTACTTCCATCTCAATGATGATCTCCATGTTCTCATTGAAGTGTTTGCCCCACCTGCAGAA
GCTTATGCCAGGATGGGACATGCTTTGGAAGAAATCAAAAAGTTCCTCATCCCTGATTATAATGATGAGATCAGGCAAGCACAGCTCCAG
GAGTTAACATATTTGAATGGTGGTTCAGAAAATGCAGATGTTCCAGTGGTTCGAGGGAAACCCACCTTGCGTACAAGAGGTGTACCAGCC
CCAGCAATAACCAGGGGAAGGGGAGGAGTTACAGCCCGGCCAGTTGGAGTTGTAGTACCACGAGGGACGCCAACTCCCAGAGGAGTCCTG
TCCACCCGAGGGCCAGTGAGTCGGGGAAGAGGACTTCTCACTCCCAGAGCAAGAGGAGTCCCCCCAACTGGGTACAGACCTCCACCGCCA
CCCCCGACACAAGAGACTTATGGAGAATATGACTATGATGATGGATATGGCACTGCTTATGATGAACAGAGTTATGATTCCTATGATAAC
AGCTATAGCACCCCAGCCCAAAGTGGTGCTGATTACTATGATTACGGACATGGACTCAGTGAGGAGACTTATGATTCCTACGGGCAAGAA
GAGTGGACTAACTCAAGACACAAGGCACCTTCAGCGAGGACAGCAAAGGGCGTCTACAGAGACCAGCCATATGGCAGATACTGATTGTAC
TGTCTGATGTTGTGAAATAGCCAATCTCCACCAGTCCTGTATACTGTTCAAAGTAATTTTTTTCTATGAACAATCCCTTTTTAAATAAAT
CAGAATGCTTAAAATCTGAATGGATGGAACTTAAAACTACTTTGTTGAAACATCAACCTGGGCAGAAAAAAAAAAAAAAAGACATGTAAA
ATTTTGTTATTTCCAGTCTGTATATGAAAAAATAGGTCATCAAAAGGAAAAAAAATAACTTTGATTAACTAGTGTTAAACAAAAAATAGG
TTTACTAAATATGTTAATCTATTCTTTTAACATAAGCCTCACCTTTCATTTTAAAGGTTTCCATAGAATTTAGTTATTTTATCTTTCAGC
CATATGCTAGTTTTTTTTTCTCTTGCCAACATGCGTAAAAAGGGAAGCCAATTACAAGTGCAAATAATGTGGTATTCTTTTGTAACTCAA

>In-frame_ENST00000405755_ENST00000355849_TCGA-63-A5MY-01A_PDE4D_chr5_58476421_-_KHDRBS3_chr8_136533480_length(amino acids)=473AA_start in transcript=102_stop in transcript=1523
MGILASSLKMAFVWDPLGATVPGPSTRAKSRLRFSKSYSFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSP
KSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEIEKFQKGEGKDEEKYIDVVINKN
MKLGQKVLIPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRKSGEAKYFHLNDDLHVLIEVFAPPAEAYAR
MGHALEEIKKFLIPDYNDEIRQAQLQELTYLNGGSENADVPVVRGKPTLRTRGVPAPAITRGRGGVTARPVGVVVPRGTPTPRGVLSTRG
PVSRGRGLLTPRARGVPPTGYRPPPPPPTQETYGEYDYDDGYGTAYDEQSYDSYDNSYSTPAQSGADYYDYGHGLSEETYDSYGQEEWTN

--------------------------------------------------------------
>In-frame_ENST00000405755_ENST00000520981_TCGA-63-A5MY-01A_PDE4D_chr5_58476421_-_KHDRBS3_chr8_136533480_length(transcript)=1450nt_BP=571nt
ACTGCACAAAGGAAATGCCCTCACTCAGCTACAAGTGCCTCCTGCTCCGTGCGGGGCCTCAGGGCCCCAGAGCCCCGCACCAGCTCTGAC
TTCTCGTGGTTCCTGGGGATCTTGGCATCGTCCTTAAAAATGGCTTTTGTTTGGGATCCTCTGGGAGCCACGGTGCCAGGACCATCTACA
AGAGCCAAATCAAGATTGCGTTTCTCAAAGTCCTACAGTTTTGATGTGGACAATGGCACATCTGCGGGACGGAGTCCCTTGGATCCCATG
ACCAGCCCAGGATCCGGGCTAATTCTCCAAGCAAATTTTGTCCACAGTCAACGACGGGAGTCCTTCCTGTATCGATCCGACAGCGATTAT
GACCTCTCTCCAAAGTCTATGTCCCGGAACTCCTCCATTGCCAGTGATATACACGGAGATGACTTGATTGTGACTCCATTTGCTCAGGTC
TTGGCCAGTCTGCGAACTGTACGAAACAACTTTGCTGCATTAACTAATTTGCAAGATCGAGCACCTAGCAAAAGATCACCCATGTGCAAC
CAACCATCCATCAACAAAGCCACCATAACAGAAATAGAAAAGTTTCAAAAAGGAGAAGGCAAGGATGAAGAAAAGTACATCGATGTGGTG
ATTAATAAGAACATGAAGCTGGGACAGAAAGTGTTAATTCCCGTAAAACAGTTCCCTAAGGACTATGATGATGGATATGGCACTGCTTAT
GATGAACAGAGTTATGATTCCTATGATAACAGCTATAGCACCCCAGCCCAAAGTGGTGCTGATTACTATGATTACGGACATGGACTCAGT
GAGGAGACTTATGATTCCTACGGGCAAGAAGAGTGGACTAACTCAAGACACAAGGCACCTTCAGCGAGGACAGCAAAGGGCGTCTACAGA
GACCAGCCATATGGCAGATACTGATTGTACTGTCTGATGTTGTGAAATAGCCAATCTCCACCAGTCCTGTATACTGTTCAAAGTAATTTT
TTTCTATGAACAATCCCTTTTTAAATAAATCAGAATGCTTAAAATCTGAATGGATGGAACTTAAAACTACTTTGTTGAAACATCAACCTG
GGCAGAAAAAAAAAAAAAAAGACATGTAAAATTTTGTTATTTCCAGTCTGTATATGAAAAAATAGGTCATCAAAAGGAAAAAAAATAACT
TTGATTAACTAGTGTTAAACAAAAAATAGGTTTACTAAATATGTTAATCTATTCTTTTAACATAAGCCTCACCTTTCATTTTAAAGGTTT
CCATAGAATTTAGTTATTTTATCTTTCAGCCATATGCTAGTTTTTTTTTCTCTTGCCAACATGCGTAAAAAGGGAAGCCAATTACAAGTG
CAAATAATGTGGTATTCTTTTGTAACTCAAGTCTTGAAATGTTCTGTAGTGTTAAGCAAAGTCTCCTCTTGCTTGATACTAAATAAACTT

>In-frame_ENST00000405755_ENST00000520981_TCGA-63-A5MY-01A_PDE4D_chr5_58476421_-_KHDRBS3_chr8_136533480_length(amino acids)=273AA_start in transcript=102_stop in transcript=923
MGILASSLKMAFVWDPLGATVPGPSTRAKSRLRFSKSYSFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSP
KSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEIEKFQKGEGKDEEKYIDVVINKN
MKLGQKVLIPVKQFPKDYDDGYGTAYDEQSYDSYDNSYSTPAQSGADYYDYGHGLSEETYDSYGQEEWTNSRHKAPSARTAKGVYRDQPY

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Fusion Gene PPI Analysis for PDE4D-KHDRBS3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for PDE4D-KHDRBS3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for PDE4D-KHDRBS3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgenePDE4DC3553250ACRODYSOSTOSIS 2 WITH OR WITHOUT HORMONE RESISTANCE4CTD_human;GENOMICS_ENGLAND;UNIPROT
HgenePDE4DC0011581Depressive disorder3PSYGENET
HgenePDE4DC0004096Asthma2CTD_human
HgenePDE4DC0011570Mental Depression2PSYGENET
HgenePDE4DC0033578Prostatic Neoplasms2CTD_human
HgenePDE4DC0220659Acrodysostosis2CTD_human;GENOMICS_ENGLAND;ORPHANET
HgenePDE4DC0376358Malignant neoplasm of prostate2CTD_human
HgenePDE4DC0036341Schizophrenia1PSYGENET
HgenePDE4DC0236733Amphetamine-Related Disorders1CTD_human
HgenePDE4DC0236804Amphetamine Addiction1CTD_human
HgenePDE4DC0236807Amphetamine Abuse1CTD_human
HgenePDE4DC3276228ACRODYSOSTOSIS 1 WITH OR WITHOUT HORMONE RESISTANCE1CTD_human;GENOMICS_ENGLAND