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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:PGM1-FOXJ3 (FusionGDB2 ID:64215)

Fusion Gene Summary for PGM1-FOXJ3

check button Fusion gene summary
Fusion gene informationFusion gene name: PGM1-FOXJ3
Fusion gene ID: 64215
HgeneTgene
Gene symbol

PGM1

FOXJ3

Gene ID

5236

22887

Gene namephosphoglucomutase 1forkhead box J3
SynonymsCDG1T|GSD14-
Cytomap

1p31.3

1p34.2

Type of geneprotein-codingprotein-coding
Descriptionphosphoglucomutase-1PGM 1glucose phosphomutase 1forkhead box protein J3
Modification date2020031320200313
UniProtAcc.

Q9UPW0

Ensembl transtripts involved in fusion geneENST00000371084, ENST00000540265, 
ENST00000371083, ENST00000483707, 
ENST00000372572, ENST00000372573, 
ENST00000361346, ENST00000361776, 
ENST00000545068, ENST00000372571, 
Fusion gene scores* DoF score6 X 5 X 5=1509 X 7 X 4=252
# samples 68
** MAII scorelog2(6/150*10)=-1.32192809488736
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(8/252*10)=-1.65535182861255
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: PGM1 [Title/Abstract] AND FOXJ3 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointFOXJ3(42664773)-PGM1(64095096), # samples:2
PGM1(64059405)-FOXJ3(42660735), # samples:1
Anticipated loss of major functional domain due to fusion event.FOXJ3-PGM1 seems lost the major protein functional domain in Hgene partner, which is a transcription factor due to the frame-shifted ORF.
FOXJ3-PGM1 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
FOXJ3-PGM1 seems lost the major protein functional domain in Tgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgenePGM1

GO:0006006

glucose metabolic process

25288802

TgeneFOXJ3

GO:0045944

positive regulation of transcription by RNA polymerase II

22740631


check buttonFusion gene breakpoints across PGM1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across FOXJ3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4OVTCGA-30-1891-01APGM1chr1

64059405

+FOXJ3chr1

42660735

-


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Fusion Gene ORF analysis for PGM1-FOXJ3

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000371084ENST00000372572PGM1chr1

64059405

+FOXJ3chr1

42660735

-
In-frameENST00000371084ENST00000372573PGM1chr1

64059405

+FOXJ3chr1

42660735

-
In-frameENST00000371084ENST00000361346PGM1chr1

64059405

+FOXJ3chr1

42660735

-
In-frameENST00000371084ENST00000361776PGM1chr1

64059405

+FOXJ3chr1

42660735

-
In-frameENST00000371084ENST00000545068PGM1chr1

64059405

+FOXJ3chr1

42660735

-
5CDS-intronENST00000371084ENST00000372571PGM1chr1

64059405

+FOXJ3chr1

42660735

-
intron-3CDSENST00000540265ENST00000372572PGM1chr1

64059405

+FOXJ3chr1

42660735

-
intron-3CDSENST00000540265ENST00000372573PGM1chr1

64059405

+FOXJ3chr1

42660735

-
intron-3CDSENST00000540265ENST00000361346PGM1chr1

64059405

+FOXJ3chr1

42660735

-
intron-3CDSENST00000540265ENST00000361776PGM1chr1

64059405

+FOXJ3chr1

42660735

-
intron-3CDSENST00000540265ENST00000545068PGM1chr1

64059405

+FOXJ3chr1

42660735

-
intron-intronENST00000540265ENST00000372571PGM1chr1

64059405

+FOXJ3chr1

42660735

-
intron-3CDSENST00000371083ENST00000372572PGM1chr1

64059405

+FOXJ3chr1

42660735

-
intron-3CDSENST00000371083ENST00000372573PGM1chr1

64059405

+FOXJ3chr1

42660735

-
intron-3CDSENST00000371083ENST00000361346PGM1chr1

64059405

+FOXJ3chr1

42660735

-
intron-3CDSENST00000371083ENST00000361776PGM1chr1

64059405

+FOXJ3chr1

42660735

-
intron-3CDSENST00000371083ENST00000545068PGM1chr1

64059405

+FOXJ3chr1

42660735

-
intron-intronENST00000371083ENST00000372571PGM1chr1

64059405

+FOXJ3chr1

42660735

-
intron-3CDSENST00000483707ENST00000372572PGM1chr1

64059405

+FOXJ3chr1

42660735

-
intron-3CDSENST00000483707ENST00000372573PGM1chr1

64059405

+FOXJ3chr1

42660735

-
intron-3CDSENST00000483707ENST00000361346PGM1chr1

64059405

+FOXJ3chr1

42660735

-
intron-3CDSENST00000483707ENST00000361776PGM1chr1

64059405

+FOXJ3chr1

42660735

-
intron-3CDSENST00000483707ENST00000545068PGM1chr1

64059405

+FOXJ3chr1

42660735

-
intron-intronENST00000483707ENST00000372571PGM1chr1

64059405

+FOXJ3chr1

42660735

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000371084PGM1chr164059405+ENST00000372572FOXJ3chr142660735-4740459541568504
ENST00000371084PGM1chr164059405+ENST00000372573FOXJ3chr142660735-4740459541568504
ENST00000371084PGM1chr164059405+ENST00000361346FOXJ3chr142660735-4734459541568504
ENST00000371084PGM1chr164059405+ENST00000361776FOXJ3chr142660735-4734459541568504
ENST00000371084PGM1chr164059405+ENST00000545068FOXJ3chr142660735-4730459541568504

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000371084ENST00000372572PGM1chr164059405+FOXJ3chr142660735-0.0050077350.9949923
ENST00000371084ENST00000372573PGM1chr164059405+FOXJ3chr142660735-0.0050077350.9949923
ENST00000371084ENST00000361346PGM1chr164059405+FOXJ3chr142660735-0.0050856890.9949143
ENST00000371084ENST00000361776PGM1chr164059405+FOXJ3chr142660735-0.0050856890.9949143
ENST00000371084ENST00000545068PGM1chr164059405+FOXJ3chr142660735-0.0050546360.99494535

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Fusion Genomic Features for PGM1-FOXJ3


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for PGM1-FOXJ3


check button Go to

FGviewer for the breakpoints of chr1:64059405-chr1:42660735

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.FOXJ3

Q9UPW0

FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Transcriptional activator of MEF2C involved in the regulation of adult muscle fiber type identity and skeletal muscle regeneration (By similarity). Plays an important role in spermatogenesis (By similarity). Required for the survival of spermatogonia and participates in spermatocyte meiosis (By similarity). {ECO:0000250|UniProtKB:Q8BUR3}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePGM1chr1:64059405chr1:42660735ENST00000371083+111117_1180581.0RegionSubstrate binding
HgenePGM1chr1:64059405chr1:42660735ENST00000371083+111292_2930581.0RegionSubstrate binding
HgenePGM1chr1:64059405chr1:42660735ENST00000371083+111376_3780581.0RegionSubstrate binding
HgenePGM1chr1:64059405chr1:42660735ENST00000371084+111117_11882.0563.0RegionSubstrate binding
HgenePGM1chr1:64059405chr1:42660735ENST00000371084+111292_29382.0563.0RegionSubstrate binding
HgenePGM1chr1:64059405chr1:42660735ENST00000371084+111376_37882.0563.0RegionSubstrate binding
HgenePGM1chr1:64059405chr1:42660735ENST00000540265+111117_1180366.0RegionSubstrate binding
HgenePGM1chr1:64059405chr1:42660735ENST00000540265+111292_2930366.0RegionSubstrate binding
HgenePGM1chr1:64059405chr1:42660735ENST00000540265+111376_3780366.0RegionSubstrate binding
TgeneFOXJ3chr1:64059405chr1:42660735ENST0000036134661377_168253.0623.0DNA bindingFork-head
TgeneFOXJ3chr1:64059405chr1:42660735ENST0000036177651277_168219.0589.0DNA bindingFork-head
TgeneFOXJ3chr1:64059405chr1:42660735ENST0000037257281577_168253.0623.0DNA bindingFork-head
TgeneFOXJ3chr1:64059405chr1:42660735ENST0000037257361377_168253.0623.0DNA bindingFork-head
TgeneFOXJ3chr1:64059405chr1:42660735ENST0000054506861377_168253.0623.0DNA bindingFork-head


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Fusion Gene Sequence for PGM1-FOXJ3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000371084_ENST00000372572_TCGA-30-1891-01A_PGM1_chr1_64059405_+_FOXJ3_chr1_42660735_length(transcript)=4740nt_BP=459nt
CCTTTCCCCTCCCGCCGGACCTGCCAGGAGGTGGGCTGGCGCGGAGGGAGGGCCCTGTCCCCTGTCCCTTTAAGGAGGAGGGCCAAACGC
CGGCCTAGAGTGCGGCGTAGCCCCCACCCGCCGTGCCCTCACCCCAGAGCAGCTGCAGCCTCAGCCGGCCGCCCCTCCGCCAGCCAAGTC
CGCCGCTCTGACCCCCGGCAGCAAGTCGCCACCATGGTGAAGATCGTGACAGTTAAGACCCAGGCGTACCAGGACCAGAAGCCGGGCACG
AGCGGGCTGCGGAAGCGGGTGAAGGTGTTCCAGAGCAGCGCCAACTACGCGGAGAACTTCATCCAGAGTATCATCTCCACCGTGGAGCCG
GCGCAGCGGCAGGAGGCCACGCTGGTGGTGGGCGGGGACGGCCGGTTCTACATGAAGGAGGCCATCCAGCTCATCGCTCGCATCGCTGCC
GCCAACGGGGTGACAAGCCATCCAGAATCAGTCTCTCAATCATTAACTCCTCAGCAGCAACCACAGTACAACCTTCCAGAAAGAGACAAG
CAACTACTTTTCTCAGAATATAATTTTGAAGATCTTAGTGCCTCATTTCGGAGCCTTTATAAGTCAGTTTTTGAGCAGTCACTTAGTCAA
CAAGGTTTGATGAACATCCCTTCTGAATCTTCCCAGCAGTCCCACACTTCATGTACCTATCAGCACTCTCCCAGCAGTACAGTGAGCACT
CACCCACACAGCAACCAAAGCAGCCTGTCCAACAGTCATGGCAGTGGCCTCAACACCACAGGCAGTAATTCGGTTGCACAGGTCTCACTG
TCTCACCCCCAGATGCACACACAGCCATCTCCACATCCTCCCCATCGACCGCATGGTTTACCGCAGCATCCGCAGCGTTCCCCACACCCA
GCACCACACCCACAGCAACACAGCCAGCTCCAGTCCCCTCACCCCCAGCATCCCTCTCCACATCAACACATACAGCACCATCCGAACCAT
CAGCATCAGACGTTAACACATCAGGCACCCCCACCCCCACAACAGGTATCCTGTAATTCTGGTGTTTCAAATGATTGGTATGCGACACTT
GATATGCTAAAAGAAAGCTGTCGAATTGCCAGCAGTGTTAATTGGTCAGATGTAGACCTTTCACAGTTTCAAGGTCTGATGGAGAGTATG
AGACAGGCAGATCTCAAGAACTGGTCTTTAGACCAGGTTCAGTTTGCCGATCTTTGTTCTTCTCTTAATCAGTTCTTTACACAAACTGGC
CTTATACATTCACAGAGTAATGTTCAACAAAATGTTTGTCATGGTGCCATGCATCCAACAAAACCTTCCCAACACATTGGAACAGGAAAT
TTGTACATAGATTCTAGGCAAAATCTCCCTCCTTCAGTGATGCCACCCCCTGGTTATCCTCATATCCCACAGGCACTCAGCACTCCAGGA
ACAACGATGGCAGGCCATCACAGAGCCATGAACCAGCAGCACATGATGCCTTCCCAAGCCTTCCAGATGCGGCGTTCCCTGCCTCCAGAT
GACATCCAGGATGACTTTGATTGGGATTCAATTGTGTAGGGCTTGTTTCTGCAAGACACCAGACCCTAACGTTACCTTTCTGTGCAGTGA
AGGGAAAGGTTTAAGAGAATCCAGTTGAGAAAACAAACTTGCTAATCACTTTACCAATGTTATCAAAATTACTTTTGAAGACAATCAGAA
GGATTTTAGCTGGATAACTTACTGCTTTTATCTGACCCAAGCAAGTACTACATGTTTGTCTCCCTGCCAGCTGCCCTATGTAGCTCCTAA
CTGTTGTGTGATTTGGACGGCTTTTTGCATATTTGTGTCAGTTTGATGTTAACCACAAGTGCCAGACTGATTTTTCAGACGGAGCCTATT
TTGCTGCAAGCAGTTTATATAAAGATACATATGTGTAAATATATGTACAAAAATTACTGAAAGGCTTCAGTTTTTTCTAATTGGATTATT
ATGTCTTGAAAGTTATTGTCAGTTTTTATTCCTTGTTAGGCTATTTTCTGCAGGATGCTTTTAACTGATGTAGGAAACTGAAAGGAAATA
GATTTTTTCCAAAACCCAGTTCCCCTTATTTAATCTTTTTTAGAAATGTGGGTAATGAATTCTATCTAATAAGTCAAGGAAACCAGAATT
TGACACACTCCAACAATCCGAAGGGGCATGTTGCTCCTGAGCAGCATGAAGAACTGACCAAATTGGTTTTGATGCTTGGGGGATCATAGA
GTATTTATGTCTGCTTTTCTAAATCTGCATTATAATAGCTCTAAAATTTGTTGATTGGTAAGAAATTGGGCATTGCTTGGCTCTTTAAAC
ACATCAGTGCTTCCACATTCACCTATGTATTTATTATTCAAAAGTGTCATTTTAATATTTATTGCTACCTTCTGTGAATGCTTAGCTCCT
GTCGGGTTCATTAAGGAGAAATGTGTCTGAAAGCACAGAACTATTATTATTTTTTTCTTTTTTTGAGATGGAGTCTTGCCCTGTTGCCCA
GGCTGGAGTGCAGTGGCACGATCTCGGCTCACTGCAACCTCCGCCTCCCGGGTTCAAGCAATTCTCCTGCCTCAGCCTCCCGAGTAGCTG
GGAGTGCAGGTGCACACCGCCATGCCTGGCTGATTTTTTGTATTTTAGTAGAGATGGGGTTTCACCATGTTGCCTGGGCTGGTTGCAAAC
TCTTGAGCTCAGGCAGTCTGCCTGCCTCAGCCTCCTAGAGTGCTGGGATTACAGACATGAGCCACTGCGCCTGGCCCAGCGTTACTTTTC
TTGATAAGAATTTACAGATAAGACACTCAGAGAGACATTGTGTCATTCTCTATCATCACTCCTTTTACCATGTGAATAGATTTCTCTGTC
TTGGCATTCTTGCTGATTCAGACTTATTAGTTAAATCGGATTTTTCTGGAATTTGAATCAGATTTCATTTGGGCAACAACAGCAGGGCAG
GGTTTCTAAAGCAGGTTTCCCCACTCATCTAGGTTGTCTTGAAAGGAGGATAGAGCCACTTACAGTTTTATTTGCTTCAGTGTTTAATGT
AGATATTATGTGGCCTGCTGTTTCTGTTGTCTTGTATGTCTGTGTATGCATGACATTTGGTCCCTTTCTTTGAAATGCAGCCCCTCTTAC
GGGTTTTTTAGTGGTGGTGGTTTGTTTTGTTTCATATCATATCACAGTTTGCATGGACTGATTATCTTAGTTTTATGATAAAACTAGAAG
AAATGAGGGTTTTTTTTTAATGAATAGATTTTGAATTGATTCTTTAGACCCCCCAAAAAGTGTCAGTTCTAATGGGGAAATATATTCCAT
CAAGTCAAAGAGTAATAACTGCTCACTAGTTGCTTTTTAGCATCTCTGGTCTTATCAGCCATGCTAAATCACTTTAATTAGCCTTAGTGA
TTCTATGGTTGAGTAATCTCTACTTGAACTAAACAAACATCTTTTGTTTCTGTGTGTGTGTGCTGTGTGTGAGAGTGTGCGCGCGCGTGT
GTGTGTGTGTGTTTTAATGGAGTGTTGCCTTGAATGAATCACTGGGAAGCCAGCCATGGTAAGGGCTGGTGAGGTTGGGGAGAAAGGAAG
AGCTTTATGTTTCTCTGTTGTTTGGACCCTACTTGGCATGAAAAAGGAAGCTCAGTTCCAGCCCCTTGGATCAACGAAAATCAGAGGATT
CTGGAAAGGCAGCCAACTTGCGCCTCTTAGAAGGATCAGAGGCAAGATGAGATGGCAGCCTGCAGAGTAAATGCTTGAAAAAAGAGGGGT
GATTTTCAATGGTTTGCTTAAGTCACTGTTTTCTAGACACCAAAATAGCTGTTTTGAAACTGTTTTAATTGCTTGGGTAGCAATGTGCAC
TTTAAACAATTTGGATATTGGAATGCAGTCTCATACTGAGTGATTTGAGTAGAACCACTGATGATGATTTTATAAATTGTGTGAAGCGAA
TTTCCCATTTGGCAATCATTTACTGATTTGCAGTGATGAATATTTTTATGAGAATTTAAACTTAGCAAGAATGGCCATGGAGGCAAAGCC
TTCACCCAGACCCATCCCACTCTCCTGTGATCCAGGTGGTCCAGGAGCCCAGGACAGGCCTTTTCTGTGGGCCCTGGCCAGACAGGGTTA
CCTGGTGAGGTGCAGAGAGTCCCTCTAGTGGCCATTTTGTATGGTAGTTGCTAATGCAGAACAAGTTCTGTCTTGGGCTTAAATTGACTG
AAGACTTTAGGGGGAAAGAATAGTAAATGCATGTAAACAAATGGGGACACTCTGTTCAGGAGAATAATCCGACTGGCATTTGTGGCAGTT
TTTGAAATGTAAATGTATTCATGTGTGTTCTTGTAAATACGTGTCGCTCAGATGTCCTTTGAAGTGGGAGGGAATCAATCCGGGGATAAT
TTCAAATGGAATAGAGTATTTTGATATTGTTCATTCAGAGGGTGATGTGTACATATCTATATTGTATATATGTGATGAAAATGCATTGGC
TTTTTGTGCAGATACAACCTGCTCTCTGTACTGCTGTTGGACAGTCAGTGTTTTAATGTTTCTACAGTTTTGCTATTGCACGATTTCATA
TTTTGCCTCTATGATGAACGGCAACCATTATTTGTAACTGTTTAGTGCTGTAAAGAAATATTCCAAGTGTCATTAGGATTGTTGCTGCCA

>In-frame_ENST00000371084_ENST00000372572_TCGA-30-1891-01A_PGM1_chr1_64059405_+_FOXJ3_chr1_42660735_length(amino acids)=504AA_start in transcript=54_stop in transcript=1568
MSPVPLRRRAKRRPRVRRSPHPPCPHPRAAAASAGRPSASQVRRSDPRQQVATMVKIVTVKTQAYQDQKPGTSGLRKRVKVFQSSANYAE
NFIQSIISTVEPAQRQEATLVVGGDGRFYMKEAIQLIARIAAANGVTSHPESVSQSLTPQQQPQYNLPERDKQLLFSEYNFEDLSASFRS
LYKSVFEQSLSQQGLMNIPSESSQQSHTSCTYQHSPSSTVSTHPHSNQSSLSNSHGSGLNTTGSNSVAQVSLSHPQMHTQPSPHPPHRPH
GLPQHPQRSPHPAPHPQQHSQLQSPHPQHPSPHQHIQHHPNHQHQTLTHQAPPPPQQVSCNSGVSNDWYATLDMLKESCRIASSVNWSDV
DLSQFQGLMESMRQADLKNWSLDQVQFADLCSSLNQFFTQTGLIHSQSNVQQNVCHGAMHPTKPSQHIGTGNLYIDSRQNLPPSVMPPPG

--------------------------------------------------------------
>In-frame_ENST00000371084_ENST00000372573_TCGA-30-1891-01A_PGM1_chr1_64059405_+_FOXJ3_chr1_42660735_length(transcript)=4740nt_BP=459nt
CCTTTCCCCTCCCGCCGGACCTGCCAGGAGGTGGGCTGGCGCGGAGGGAGGGCCCTGTCCCCTGTCCCTTTAAGGAGGAGGGCCAAACGC
CGGCCTAGAGTGCGGCGTAGCCCCCACCCGCCGTGCCCTCACCCCAGAGCAGCTGCAGCCTCAGCCGGCCGCCCCTCCGCCAGCCAAGTC
CGCCGCTCTGACCCCCGGCAGCAAGTCGCCACCATGGTGAAGATCGTGACAGTTAAGACCCAGGCGTACCAGGACCAGAAGCCGGGCACG
AGCGGGCTGCGGAAGCGGGTGAAGGTGTTCCAGAGCAGCGCCAACTACGCGGAGAACTTCATCCAGAGTATCATCTCCACCGTGGAGCCG
GCGCAGCGGCAGGAGGCCACGCTGGTGGTGGGCGGGGACGGCCGGTTCTACATGAAGGAGGCCATCCAGCTCATCGCTCGCATCGCTGCC
GCCAACGGGGTGACAAGCCATCCAGAATCAGTCTCTCAATCATTAACTCCTCAGCAGCAACCACAGTACAACCTTCCAGAAAGAGACAAG
CAACTACTTTTCTCAGAATATAATTTTGAAGATCTTAGTGCCTCATTTCGGAGCCTTTATAAGTCAGTTTTTGAGCAGTCACTTAGTCAA
CAAGGTTTGATGAACATCCCTTCTGAATCTTCCCAGCAGTCCCACACTTCATGTACCTATCAGCACTCTCCCAGCAGTACAGTGAGCACT
CACCCACACAGCAACCAAAGCAGCCTGTCCAACAGTCATGGCAGTGGCCTCAACACCACAGGCAGTAATTCGGTTGCACAGGTCTCACTG
TCTCACCCCCAGATGCACACACAGCCATCTCCACATCCTCCCCATCGACCGCATGGTTTACCGCAGCATCCGCAGCGTTCCCCACACCCA
GCACCACACCCACAGCAACACAGCCAGCTCCAGTCCCCTCACCCCCAGCATCCCTCTCCACATCAACACATACAGCACCATCCGAACCAT
CAGCATCAGACGTTAACACATCAGGCACCCCCACCCCCACAACAGGTATCCTGTAATTCTGGTGTTTCAAATGATTGGTATGCGACACTT
GATATGCTAAAAGAAAGCTGTCGAATTGCCAGCAGTGTTAATTGGTCAGATGTAGACCTTTCACAGTTTCAAGGTCTGATGGAGAGTATG
AGACAGGCAGATCTCAAGAACTGGTCTTTAGACCAGGTTCAGTTTGCCGATCTTTGTTCTTCTCTTAATCAGTTCTTTACACAAACTGGC
CTTATACATTCACAGAGTAATGTTCAACAAAATGTTTGTCATGGTGCCATGCATCCAACAAAACCTTCCCAACACATTGGAACAGGAAAT
TTGTACATAGATTCTAGGCAAAATCTCCCTCCTTCAGTGATGCCACCCCCTGGTTATCCTCATATCCCACAGGCACTCAGCACTCCAGGA
ACAACGATGGCAGGCCATCACAGAGCCATGAACCAGCAGCACATGATGCCTTCCCAAGCCTTCCAGATGCGGCGTTCCCTGCCTCCAGAT
GACATCCAGGATGACTTTGATTGGGATTCAATTGTGTAGGGCTTGTTTCTGCAAGACACCAGACCCTAACGTTACCTTTCTGTGCAGTGA
AGGGAAAGGTTTAAGAGAATCCAGTTGAGAAAACAAACTTGCTAATCACTTTACCAATGTTATCAAAATTACTTTTGAAGACAATCAGAA
GGATTTTAGCTGGATAACTTACTGCTTTTATCTGACCCAAGCAAGTACTACATGTTTGTCTCCCTGCCAGCTGCCCTATGTAGCTCCTAA
CTGTTGTGTGATTTGGACGGCTTTTTGCATATTTGTGTCAGTTTGATGTTAACCACAAGTGCCAGACTGATTTTTCAGACGGAGCCTATT
TTGCTGCAAGCAGTTTATATAAAGATACATATGTGTAAATATATGTACAAAAATTACTGAAAGGCTTCAGTTTTTTCTAATTGGATTATT
ATGTCTTGAAAGTTATTGTCAGTTTTTATTCCTTGTTAGGCTATTTTCTGCAGGATGCTTTTAACTGATGTAGGAAACTGAAAGGAAATA
GATTTTTTCCAAAACCCAGTTCCCCTTATTTAATCTTTTTTAGAAATGTGGGTAATGAATTCTATCTAATAAGTCAAGGAAACCAGAATT
TGACACACTCCAACAATCCGAAGGGGCATGTTGCTCCTGAGCAGCATGAAGAACTGACCAAATTGGTTTTGATGCTTGGGGGATCATAGA
GTATTTATGTCTGCTTTTCTAAATCTGCATTATAATAGCTCTAAAATTTGTTGATTGGTAAGAAATTGGGCATTGCTTGGCTCTTTAAAC
ACATCAGTGCTTCCACATTCACCTATGTATTTATTATTCAAAAGTGTCATTTTAATATTTATTGCTACCTTCTGTGAATGCTTAGCTCCT
GTCGGGTTCATTAAGGAGAAATGTGTCTGAAAGCACAGAACTATTATTATTTTTTTCTTTTTTTGAGATGGAGTCTTGCCCTGTTGCCCA
GGCTGGAGTGCAGTGGCACGATCTCGGCTCACTGCAACCTCCGCCTCCCGGGTTCAAGCAATTCTCCTGCCTCAGCCTCCCGAGTAGCTG
GGAGTGCAGGTGCACACCGCCATGCCTGGCTGATTTTTTGTATTTTAGTAGAGATGGGGTTTCACCATGTTGCCTGGGCTGGTTGCAAAC
TCTTGAGCTCAGGCAGTCTGCCTGCCTCAGCCTCCTAGAGTGCTGGGATTACAGACATGAGCCACTGCGCCTGGCCCAGCGTTACTTTTC
TTGATAAGAATTTACAGATAAGACACTCAGAGAGACATTGTGTCATTCTCTATCATCACTCCTTTTACCATGTGAATAGATTTCTCTGTC
TTGGCATTCTTGCTGATTCAGACTTATTAGTTAAATCGGATTTTTCTGGAATTTGAATCAGATTTCATTTGGGCAACAACAGCAGGGCAG
GGTTTCTAAAGCAGGTTTCCCCACTCATCTAGGTTGTCTTGAAAGGAGGATAGAGCCACTTACAGTTTTATTTGCTTCAGTGTTTAATGT
AGATATTATGTGGCCTGCTGTTTCTGTTGTCTTGTATGTCTGTGTATGCATGACATTTGGTCCCTTTCTTTGAAATGCAGCCCCTCTTAC
GGGTTTTTTAGTGGTGGTGGTTTGTTTTGTTTCATATCATATCACAGTTTGCATGGACTGATTATCTTAGTTTTATGATAAAACTAGAAG
AAATGAGGGTTTTTTTTTAATGAATAGATTTTGAATTGATTCTTTAGACCCCCCAAAAAGTGTCAGTTCTAATGGGGAAATATATTCCAT
CAAGTCAAAGAGTAATAACTGCTCACTAGTTGCTTTTTAGCATCTCTGGTCTTATCAGCCATGCTAAATCACTTTAATTAGCCTTAGTGA
TTCTATGGTTGAGTAATCTCTACTTGAACTAAACAAACATCTTTTGTTTCTGTGTGTGTGTGCTGTGTGTGAGAGTGTGCGCGCGCGTGT
GTGTGTGTGTGTTTTAATGGAGTGTTGCCTTGAATGAATCACTGGGAAGCCAGCCATGGTAAGGGCTGGTGAGGTTGGGGAGAAAGGAAG
AGCTTTATGTTTCTCTGTTGTTTGGACCCTACTTGGCATGAAAAAGGAAGCTCAGTTCCAGCCCCTTGGATCAACGAAAATCAGAGGATT
CTGGAAAGGCAGCCAACTTGCGCCTCTTAGAAGGATCAGAGGCAAGATGAGATGGCAGCCTGCAGAGTAAATGCTTGAAAAAAGAGGGGT
GATTTTCAATGGTTTGCTTAAGTCACTGTTTTCTAGACACCAAAATAGCTGTTTTGAAACTGTTTTAATTGCTTGGGTAGCAATGTGCAC
TTTAAACAATTTGGATATTGGAATGCAGTCTCATACTGAGTGATTTGAGTAGAACCACTGATGATGATTTTATAAATTGTGTGAAGCGAA
TTTCCCATTTGGCAATCATTTACTGATTTGCAGTGATGAATATTTTTATGAGAATTTAAACTTAGCAAGAATGGCCATGGAGGCAAAGCC
TTCACCCAGACCCATCCCACTCTCCTGTGATCCAGGTGGTCCAGGAGCCCAGGACAGGCCTTTTCTGTGGGCCCTGGCCAGACAGGGTTA
CCTGGTGAGGTGCAGAGAGTCCCTCTAGTGGCCATTTTGTATGGTAGTTGCTAATGCAGAACAAGTTCTGTCTTGGGCTTAAATTGACTG
AAGACTTTAGGGGGAAAGAATAGTAAATGCATGTAAACAAATGGGGACACTCTGTTCAGGAGAATAATCCGACTGGCATTTGTGGCAGTT
TTTGAAATGTAAATGTATTCATGTGTGTTCTTGTAAATACGTGTCGCTCAGATGTCCTTTGAAGTGGGAGGGAATCAATCCGGGGATAAT
TTCAAATGGAATAGAGTATTTTGATATTGTTCATTCAGAGGGTGATGTGTACATATCTATATTGTATATATGTGATGAAAATGCATTGGC
TTTTTGTGCAGATACAACCTGCTCTCTGTACTGCTGTTGGACAGTCAGTGTTTTAATGTTTCTACAGTTTTGCTATTGCACGATTTCATA
TTTTGCCTCTATGATGAACGGCAACCATTATTTGTAACTGTTTAGTGCTGTAAAGAAATATTCCAAGTGTCATTAGGATTGTTGCTGCCA

>In-frame_ENST00000371084_ENST00000372573_TCGA-30-1891-01A_PGM1_chr1_64059405_+_FOXJ3_chr1_42660735_length(amino acids)=504AA_start in transcript=54_stop in transcript=1568
MSPVPLRRRAKRRPRVRRSPHPPCPHPRAAAASAGRPSASQVRRSDPRQQVATMVKIVTVKTQAYQDQKPGTSGLRKRVKVFQSSANYAE
NFIQSIISTVEPAQRQEATLVVGGDGRFYMKEAIQLIARIAAANGVTSHPESVSQSLTPQQQPQYNLPERDKQLLFSEYNFEDLSASFRS
LYKSVFEQSLSQQGLMNIPSESSQQSHTSCTYQHSPSSTVSTHPHSNQSSLSNSHGSGLNTTGSNSVAQVSLSHPQMHTQPSPHPPHRPH
GLPQHPQRSPHPAPHPQQHSQLQSPHPQHPSPHQHIQHHPNHQHQTLTHQAPPPPQQVSCNSGVSNDWYATLDMLKESCRIASSVNWSDV
DLSQFQGLMESMRQADLKNWSLDQVQFADLCSSLNQFFTQTGLIHSQSNVQQNVCHGAMHPTKPSQHIGTGNLYIDSRQNLPPSVMPPPG

--------------------------------------------------------------
>In-frame_ENST00000371084_ENST00000361346_TCGA-30-1891-01A_PGM1_chr1_64059405_+_FOXJ3_chr1_42660735_length(transcript)=4734nt_BP=459nt
CCTTTCCCCTCCCGCCGGACCTGCCAGGAGGTGGGCTGGCGCGGAGGGAGGGCCCTGTCCCCTGTCCCTTTAAGGAGGAGGGCCAAACGC
CGGCCTAGAGTGCGGCGTAGCCCCCACCCGCCGTGCCCTCACCCCAGAGCAGCTGCAGCCTCAGCCGGCCGCCCCTCCGCCAGCCAAGTC
CGCCGCTCTGACCCCCGGCAGCAAGTCGCCACCATGGTGAAGATCGTGACAGTTAAGACCCAGGCGTACCAGGACCAGAAGCCGGGCACG
AGCGGGCTGCGGAAGCGGGTGAAGGTGTTCCAGAGCAGCGCCAACTACGCGGAGAACTTCATCCAGAGTATCATCTCCACCGTGGAGCCG
GCGCAGCGGCAGGAGGCCACGCTGGTGGTGGGCGGGGACGGCCGGTTCTACATGAAGGAGGCCATCCAGCTCATCGCTCGCATCGCTGCC
GCCAACGGGGTGACAAGCCATCCAGAATCAGTCTCTCAATCATTAACTCCTCAGCAGCAACCACAGTACAACCTTCCAGAAAGAGACAAG
CAACTACTTTTCTCAGAATATAATTTTGAAGATCTTAGTGCCTCATTTCGGAGCCTTTATAAGTCAGTTTTTGAGCAGTCACTTAGTCAA
CAAGGTTTGATGAACATCCCTTCTGAATCTTCCCAGCAGTCCCACACTTCATGTACCTATCAGCACTCTCCCAGCAGTACAGTGAGCACT
CACCCACACAGCAACCAAAGCAGCCTGTCCAACAGTCATGGCAGTGGCCTCAACACCACAGGCAGTAATTCGGTTGCACAGGTCTCACTG
TCTCACCCCCAGATGCACACACAGCCATCTCCACATCCTCCCCATCGACCGCATGGTTTACCGCAGCATCCGCAGCGTTCCCCACACCCA
GCACCACACCCACAGCAACACAGCCAGCTCCAGTCCCCTCACCCCCAGCATCCCTCTCCACATCAACACATACAGCACCATCCGAACCAT
CAGCATCAGACGTTAACACATCAGGCACCCCCACCCCCACAACAGGTATCCTGTAATTCTGGTGTTTCAAATGATTGGTATGCGACACTT
GATATGCTAAAAGAAAGCTGTCGAATTGCCAGCAGTGTTAATTGGTCAGATGTAGACCTTTCACAGTTTCAAGGTCTGATGGAGAGTATG
AGACAGGCAGATCTCAAGAACTGGTCTTTAGACCAGGTTCAGTTTGCCGATCTTTGTTCTTCTCTTAATCAGTTCTTTACACAAACTGGC
CTTATACATTCACAGAGTAATGTTCAACAAAATGTTTGTCATGGTGCCATGCATCCAACAAAACCTTCCCAACACATTGGAACAGGAAAT
TTGTACATAGATTCTAGGCAAAATCTCCCTCCTTCAGTGATGCCACCCCCTGGTTATCCTCATATCCCACAGGCACTCAGCACTCCAGGA
ACAACGATGGCAGGCCATCACAGAGCCATGAACCAGCAGCACATGATGCCTTCCCAAGCCTTCCAGATGCGGCGTTCCCTGCCTCCAGAT
GACATCCAGGATGACTTTGATTGGGATTCAATTGTGTAGGGCTTGTTTCTGCAAGACACCAGACCCTAACGTTACCTTTCTGTGCAGTGA
AGGGAAAGGTTTAAGAGAATCCAGTTGAGAAAACAAACTTGCTAATCACTTTACCAATGTTATCAAAATTACTTTTGAAGACAATCAGAA
GGATTTTAGCTGGATAACTTACTGCTTTTATCTGACCCAAGCAAGTACTACATGTTTGTCTCCCTGCCAGCTGCCCTATGTAGCTCCTAA
CTGTTGTGTGATTTGGACGGCTTTTTGCATATTTGTGTCAGTTTGATGTTAACCACAAGTGCCAGACTGATTTTTCAGACGGAGCCTATT
TTGCTGCAAGCAGTTTATATAAAGATACATATGTGTAAATATATGTACAAAAATTACTGAAAGGCTTCAGTTTTTTCTAATTGGATTATT
ATGTCTTGAAAGTTATTGTCAGTTTTTATTCCTTGTTAGGCTATTTTCTGCAGGATGCTTTTAACTGATGTAGGAAACTGAAAGGAAATA
GATTTTTTCCAAAACCCAGTTCCCCTTATTTAATCTTTTTTAGAAATGTGGGTAATGAATTCTATCTAATAAGTCAAGGAAACCAGAATT
TGACACACTCCAACAATCCGAAGGGGCATGTTGCTCCTGAGCAGCATGAAGAACTGACCAAATTGGTTTTGATGCTTGGGGGATCATAGA
GTATTTATGTCTGCTTTTCTAAATCTGCATTATAATAGCTCTAAAATTTGTTGATTGGTAAGAAATTGGGCATTGCTTGGCTCTTTAAAC
ACATCAGTGCTTCCACATTCACCTATGTATTTATTATTCAAAAGTGTCATTTTAATATTTATTGCTACCTTCTGTGAATGCTTAGCTCCT
GTCGGGTTCATTAAGGAGAAATGTGTCTGAAAGCACAGAACTATTATTATTTTTTTCTTTTTTTGAGATGGAGTCTTGCCCTGTTGCCCA
GGCTGGAGTGCAGTGGCACGATCTCGGCTCACTGCAACCTCCGCCTCCCGGGTTCAAGCAATTCTCCTGCCTCAGCCTCCCGAGTAGCTG
GGAGTGCAGGTGCACACCGCCATGCCTGGCTGATTTTTTGTATTTTAGTAGAGATGGGGTTTCACCATGTTGCCTGGGCTGGTTGCAAAC
TCTTGAGCTCAGGCAGTCTGCCTGCCTCAGCCTCCTAGAGTGCTGGGATTACAGACATGAGCCACTGCGCCTGGCCCAGCGTTACTTTTC
TTGATAAGAATTTACAGATAAGACACTCAGAGAGACATTGTGTCATTCTCTATCATCACTCCTTTTACCATGTGAATAGATTTCTCTGTC
TTGGCATTCTTGCTGATTCAGACTTATTAGTTAAATCGGATTTTTCTGGAATTTGAATCAGATTTCATTTGGGCAACAACAGCAGGGCAG
GGTTTCTAAAGCAGGTTTCCCCACTCATCTAGGTTGTCTTGAAAGGAGGATAGAGCCACTTACAGTTTTATTTGCTTCAGTGTTTAATGT
AGATATTATGTGGCCTGCTGTTTCTGTTGTCTTGTATGTCTGTGTATGCATGACATTTGGTCCCTTTCTTTGAAATGCAGCCCCTCTTAC
GGGTTTTTTAGTGGTGGTGGTTTGTTTTGTTTCATATCATATCACAGTTTGCATGGACTGATTATCTTAGTTTTATGATAAAACTAGAAG
AAATGAGGGTTTTTTTTTAATGAATAGATTTTGAATTGATTCTTTAGACCCCCCAAAAAGTGTCAGTTCTAATGGGGAAATATATTCCAT
CAAGTCAAAGAGTAATAACTGCTCACTAGTTGCTTTTTAGCATCTCTGGTCTTATCAGCCATGCTAAATCACTTTAATTAGCCTTAGTGA
TTCTATGGTTGAGTAATCTCTACTTGAACTAAACAAACATCTTTTGTTTCTGTGTGTGTGTGCTGTGTGTGAGAGTGTGCGCGCGCGTGT
GTGTGTGTGTGTTTTAATGGAGTGTTGCCTTGAATGAATCACTGGGAAGCCAGCCATGGTAAGGGCTGGTGAGGTTGGGGAGAAAGGAAG
AGCTTTATGTTTCTCTGTTGTTTGGACCCTACTTGGCATGAAAAAGGAAGCTCAGTTCCAGCCCCTTGGATCAACGAAAATCAGAGGATT
CTGGAAAGGCAGCCAACTTGCGCCTCTTAGAAGGATCAGAGGCAAGATGAGATGGCAGCCTGCAGAGTAAATGCTTGAAAAAAGAGGGGT
GATTTTCAATGGTTTGCTTAAGTCACTGTTTTCTAGACACCAAAATAGCTGTTTTGAAACTGTTTTAATTGCTTGGGTAGCAATGTGCAC
TTTAAACAATTTGGATATTGGAATGCAGTCTCATACTGAGTGATTTGAGTAGAACCACTGATGATGATTTTATAAATTGTGTGAAGCGAA
TTTCCCATTTGGCAATCATTTACTGATTTGCAGTGATGAATATTTTTATGAGAATTTAAACTTAGCAAGAATGGCCATGGAGGCAAAGCC
TTCACCCAGACCCATCCCACTCTCCTGTGATCCAGGTGGTCCAGGAGCCCAGGACAGGCCTTTTCTGTGGGCCCTGGCCAGACAGGGTTA
CCTGGTGAGGTGCAGAGAGTCCCTCTAGTGGCCATTTTGTATGGTAGTTGCTAATGCAGAACAAGTTCTGTCTTGGGCTTAAATTGACTG
AAGACTTTAGGGGGAAAGAATAGTAAATGCATGTAAACAAATGGGGACACTCTGTTCAGGAGAATAATCCGACTGGCATTTGTGGCAGTT
TTTGAAATGTAAATGTATTCATGTGTGTTCTTGTAAATACGTGTCGCTCAGATGTCCTTTGAAGTGGGAGGGAATCAATCCGGGGATAAT
TTCAAATGGAATAGAGTATTTTGATATTGTTCATTCAGAGGGTGATGTGTACATATCTATATTGTATATATGTGATGAAAATGCATTGGC
TTTTTGTGCAGATACAACCTGCTCTCTGTACTGCTGTTGGACAGTCAGTGTTTTAATGTTTCTACAGTTTTGCTATTGCACGATTTCATA
TTTTGCCTCTATGATGAACGGCAACCATTATTTGTAACTGTTTAGTGCTGTAAAGAAATATTCCAAGTGTCATTAGGATTGTTGCTGCCA

>In-frame_ENST00000371084_ENST00000361346_TCGA-30-1891-01A_PGM1_chr1_64059405_+_FOXJ3_chr1_42660735_length(amino acids)=504AA_start in transcript=54_stop in transcript=1568
MSPVPLRRRAKRRPRVRRSPHPPCPHPRAAAASAGRPSASQVRRSDPRQQVATMVKIVTVKTQAYQDQKPGTSGLRKRVKVFQSSANYAE
NFIQSIISTVEPAQRQEATLVVGGDGRFYMKEAIQLIARIAAANGVTSHPESVSQSLTPQQQPQYNLPERDKQLLFSEYNFEDLSASFRS
LYKSVFEQSLSQQGLMNIPSESSQQSHTSCTYQHSPSSTVSTHPHSNQSSLSNSHGSGLNTTGSNSVAQVSLSHPQMHTQPSPHPPHRPH
GLPQHPQRSPHPAPHPQQHSQLQSPHPQHPSPHQHIQHHPNHQHQTLTHQAPPPPQQVSCNSGVSNDWYATLDMLKESCRIASSVNWSDV
DLSQFQGLMESMRQADLKNWSLDQVQFADLCSSLNQFFTQTGLIHSQSNVQQNVCHGAMHPTKPSQHIGTGNLYIDSRQNLPPSVMPPPG

--------------------------------------------------------------
>In-frame_ENST00000371084_ENST00000361776_TCGA-30-1891-01A_PGM1_chr1_64059405_+_FOXJ3_chr1_42660735_length(transcript)=4734nt_BP=459nt
CCTTTCCCCTCCCGCCGGACCTGCCAGGAGGTGGGCTGGCGCGGAGGGAGGGCCCTGTCCCCTGTCCCTTTAAGGAGGAGGGCCAAACGC
CGGCCTAGAGTGCGGCGTAGCCCCCACCCGCCGTGCCCTCACCCCAGAGCAGCTGCAGCCTCAGCCGGCCGCCCCTCCGCCAGCCAAGTC
CGCCGCTCTGACCCCCGGCAGCAAGTCGCCACCATGGTGAAGATCGTGACAGTTAAGACCCAGGCGTACCAGGACCAGAAGCCGGGCACG
AGCGGGCTGCGGAAGCGGGTGAAGGTGTTCCAGAGCAGCGCCAACTACGCGGAGAACTTCATCCAGAGTATCATCTCCACCGTGGAGCCG
GCGCAGCGGCAGGAGGCCACGCTGGTGGTGGGCGGGGACGGCCGGTTCTACATGAAGGAGGCCATCCAGCTCATCGCTCGCATCGCTGCC
GCCAACGGGGTGACAAGCCATCCAGAATCAGTCTCTCAATCATTAACTCCTCAGCAGCAACCACAGTACAACCTTCCAGAAAGAGACAAG
CAACTACTTTTCTCAGAATATAATTTTGAAGATCTTAGTGCCTCATTTCGGAGCCTTTATAAGTCAGTTTTTGAGCAGTCACTTAGTCAA
CAAGGTTTGATGAACATCCCTTCTGAATCTTCCCAGCAGTCCCACACTTCATGTACCTATCAGCACTCTCCCAGCAGTACAGTGAGCACT
CACCCACACAGCAACCAAAGCAGCCTGTCCAACAGTCATGGCAGTGGCCTCAACACCACAGGCAGTAATTCGGTTGCACAGGTCTCACTG
TCTCACCCCCAGATGCACACACAGCCATCTCCACATCCTCCCCATCGACCGCATGGTTTACCGCAGCATCCGCAGCGTTCCCCACACCCA
GCACCACACCCACAGCAACACAGCCAGCTCCAGTCCCCTCACCCCCAGCATCCCTCTCCACATCAACACATACAGCACCATCCGAACCAT
CAGCATCAGACGTTAACACATCAGGCACCCCCACCCCCACAACAGGTATCCTGTAATTCTGGTGTTTCAAATGATTGGTATGCGACACTT
GATATGCTAAAAGAAAGCTGTCGAATTGCCAGCAGTGTTAATTGGTCAGATGTAGACCTTTCACAGTTTCAAGGTCTGATGGAGAGTATG
AGACAGGCAGATCTCAAGAACTGGTCTTTAGACCAGGTTCAGTTTGCCGATCTTTGTTCTTCTCTTAATCAGTTCTTTACACAAACTGGC
CTTATACATTCACAGAGTAATGTTCAACAAAATGTTTGTCATGGTGCCATGCATCCAACAAAACCTTCCCAACACATTGGAACAGGAAAT
TTGTACATAGATTCTAGGCAAAATCTCCCTCCTTCAGTGATGCCACCCCCTGGTTATCCTCATATCCCACAGGCACTCAGCACTCCAGGA
ACAACGATGGCAGGCCATCACAGAGCCATGAACCAGCAGCACATGATGCCTTCCCAAGCCTTCCAGATGCGGCGTTCCCTGCCTCCAGAT
GACATCCAGGATGACTTTGATTGGGATTCAATTGTGTAGGGCTTGTTTCTGCAAGACACCAGACCCTAACGTTACCTTTCTGTGCAGTGA
AGGGAAAGGTTTAAGAGAATCCAGTTGAGAAAACAAACTTGCTAATCACTTTACCAATGTTATCAAAATTACTTTTGAAGACAATCAGAA
GGATTTTAGCTGGATAACTTACTGCTTTTATCTGACCCAAGCAAGTACTACATGTTTGTCTCCCTGCCAGCTGCCCTATGTAGCTCCTAA
CTGTTGTGTGATTTGGACGGCTTTTTGCATATTTGTGTCAGTTTGATGTTAACCACAAGTGCCAGACTGATTTTTCAGACGGAGCCTATT
TTGCTGCAAGCAGTTTATATAAAGATACATATGTGTAAATATATGTACAAAAATTACTGAAAGGCTTCAGTTTTTTCTAATTGGATTATT
ATGTCTTGAAAGTTATTGTCAGTTTTTATTCCTTGTTAGGCTATTTTCTGCAGGATGCTTTTAACTGATGTAGGAAACTGAAAGGAAATA
GATTTTTTCCAAAACCCAGTTCCCCTTATTTAATCTTTTTTAGAAATGTGGGTAATGAATTCTATCTAATAAGTCAAGGAAACCAGAATT
TGACACACTCCAACAATCCGAAGGGGCATGTTGCTCCTGAGCAGCATGAAGAACTGACCAAATTGGTTTTGATGCTTGGGGGATCATAGA
GTATTTATGTCTGCTTTTCTAAATCTGCATTATAATAGCTCTAAAATTTGTTGATTGGTAAGAAATTGGGCATTGCTTGGCTCTTTAAAC
ACATCAGTGCTTCCACATTCACCTATGTATTTATTATTCAAAAGTGTCATTTTAATATTTATTGCTACCTTCTGTGAATGCTTAGCTCCT
GTCGGGTTCATTAAGGAGAAATGTGTCTGAAAGCACAGAACTATTATTATTTTTTTCTTTTTTTGAGATGGAGTCTTGCCCTGTTGCCCA
GGCTGGAGTGCAGTGGCACGATCTCGGCTCACTGCAACCTCCGCCTCCCGGGTTCAAGCAATTCTCCTGCCTCAGCCTCCCGAGTAGCTG
GGAGTGCAGGTGCACACCGCCATGCCTGGCTGATTTTTTGTATTTTAGTAGAGATGGGGTTTCACCATGTTGCCTGGGCTGGTTGCAAAC
TCTTGAGCTCAGGCAGTCTGCCTGCCTCAGCCTCCTAGAGTGCTGGGATTACAGACATGAGCCACTGCGCCTGGCCCAGCGTTACTTTTC
TTGATAAGAATTTACAGATAAGACACTCAGAGAGACATTGTGTCATTCTCTATCATCACTCCTTTTACCATGTGAATAGATTTCTCTGTC
TTGGCATTCTTGCTGATTCAGACTTATTAGTTAAATCGGATTTTTCTGGAATTTGAATCAGATTTCATTTGGGCAACAACAGCAGGGCAG
GGTTTCTAAAGCAGGTTTCCCCACTCATCTAGGTTGTCTTGAAAGGAGGATAGAGCCACTTACAGTTTTATTTGCTTCAGTGTTTAATGT
AGATATTATGTGGCCTGCTGTTTCTGTTGTCTTGTATGTCTGTGTATGCATGACATTTGGTCCCTTTCTTTGAAATGCAGCCCCTCTTAC
GGGTTTTTTAGTGGTGGTGGTTTGTTTTGTTTCATATCATATCACAGTTTGCATGGACTGATTATCTTAGTTTTATGATAAAACTAGAAG
AAATGAGGGTTTTTTTTTAATGAATAGATTTTGAATTGATTCTTTAGACCCCCCAAAAAGTGTCAGTTCTAATGGGGAAATATATTCCAT
CAAGTCAAAGAGTAATAACTGCTCACTAGTTGCTTTTTAGCATCTCTGGTCTTATCAGCCATGCTAAATCACTTTAATTAGCCTTAGTGA
TTCTATGGTTGAGTAATCTCTACTTGAACTAAACAAACATCTTTTGTTTCTGTGTGTGTGTGCTGTGTGTGAGAGTGTGCGCGCGCGTGT
GTGTGTGTGTGTTTTAATGGAGTGTTGCCTTGAATGAATCACTGGGAAGCCAGCCATGGTAAGGGCTGGTGAGGTTGGGGAGAAAGGAAG
AGCTTTATGTTTCTCTGTTGTTTGGACCCTACTTGGCATGAAAAAGGAAGCTCAGTTCCAGCCCCTTGGATCAACGAAAATCAGAGGATT
CTGGAAAGGCAGCCAACTTGCGCCTCTTAGAAGGATCAGAGGCAAGATGAGATGGCAGCCTGCAGAGTAAATGCTTGAAAAAAGAGGGGT
GATTTTCAATGGTTTGCTTAAGTCACTGTTTTCTAGACACCAAAATAGCTGTTTTGAAACTGTTTTAATTGCTTGGGTAGCAATGTGCAC
TTTAAACAATTTGGATATTGGAATGCAGTCTCATACTGAGTGATTTGAGTAGAACCACTGATGATGATTTTATAAATTGTGTGAAGCGAA
TTTCCCATTTGGCAATCATTTACTGATTTGCAGTGATGAATATTTTTATGAGAATTTAAACTTAGCAAGAATGGCCATGGAGGCAAAGCC
TTCACCCAGACCCATCCCACTCTCCTGTGATCCAGGTGGTCCAGGAGCCCAGGACAGGCCTTTTCTGTGGGCCCTGGCCAGACAGGGTTA
CCTGGTGAGGTGCAGAGAGTCCCTCTAGTGGCCATTTTGTATGGTAGTTGCTAATGCAGAACAAGTTCTGTCTTGGGCTTAAATTGACTG
AAGACTTTAGGGGGAAAGAATAGTAAATGCATGTAAACAAATGGGGACACTCTGTTCAGGAGAATAATCCGACTGGCATTTGTGGCAGTT
TTTGAAATGTAAATGTATTCATGTGTGTTCTTGTAAATACGTGTCGCTCAGATGTCCTTTGAAGTGGGAGGGAATCAATCCGGGGATAAT
TTCAAATGGAATAGAGTATTTTGATATTGTTCATTCAGAGGGTGATGTGTACATATCTATATTGTATATATGTGATGAAAATGCATTGGC
TTTTTGTGCAGATACAACCTGCTCTCTGTACTGCTGTTGGACAGTCAGTGTTTTAATGTTTCTACAGTTTTGCTATTGCACGATTTCATA
TTTTGCCTCTATGATGAACGGCAACCATTATTTGTAACTGTTTAGTGCTGTAAAGAAATATTCCAAGTGTCATTAGGATTGTTGCTGCCA

>In-frame_ENST00000371084_ENST00000361776_TCGA-30-1891-01A_PGM1_chr1_64059405_+_FOXJ3_chr1_42660735_length(amino acids)=504AA_start in transcript=54_stop in transcript=1568
MSPVPLRRRAKRRPRVRRSPHPPCPHPRAAAASAGRPSASQVRRSDPRQQVATMVKIVTVKTQAYQDQKPGTSGLRKRVKVFQSSANYAE
NFIQSIISTVEPAQRQEATLVVGGDGRFYMKEAIQLIARIAAANGVTSHPESVSQSLTPQQQPQYNLPERDKQLLFSEYNFEDLSASFRS
LYKSVFEQSLSQQGLMNIPSESSQQSHTSCTYQHSPSSTVSTHPHSNQSSLSNSHGSGLNTTGSNSVAQVSLSHPQMHTQPSPHPPHRPH
GLPQHPQRSPHPAPHPQQHSQLQSPHPQHPSPHQHIQHHPNHQHQTLTHQAPPPPQQVSCNSGVSNDWYATLDMLKESCRIASSVNWSDV
DLSQFQGLMESMRQADLKNWSLDQVQFADLCSSLNQFFTQTGLIHSQSNVQQNVCHGAMHPTKPSQHIGTGNLYIDSRQNLPPSVMPPPG

--------------------------------------------------------------
>In-frame_ENST00000371084_ENST00000545068_TCGA-30-1891-01A_PGM1_chr1_64059405_+_FOXJ3_chr1_42660735_length(transcript)=4730nt_BP=459nt
CCTTTCCCCTCCCGCCGGACCTGCCAGGAGGTGGGCTGGCGCGGAGGGAGGGCCCTGTCCCCTGTCCCTTTAAGGAGGAGGGCCAAACGC
CGGCCTAGAGTGCGGCGTAGCCCCCACCCGCCGTGCCCTCACCCCAGAGCAGCTGCAGCCTCAGCCGGCCGCCCCTCCGCCAGCCAAGTC
CGCCGCTCTGACCCCCGGCAGCAAGTCGCCACCATGGTGAAGATCGTGACAGTTAAGACCCAGGCGTACCAGGACCAGAAGCCGGGCACG
AGCGGGCTGCGGAAGCGGGTGAAGGTGTTCCAGAGCAGCGCCAACTACGCGGAGAACTTCATCCAGAGTATCATCTCCACCGTGGAGCCG
GCGCAGCGGCAGGAGGCCACGCTGGTGGTGGGCGGGGACGGCCGGTTCTACATGAAGGAGGCCATCCAGCTCATCGCTCGCATCGCTGCC
GCCAACGGGGTGACAAGCCATCCAGAATCAGTCTCTCAATCATTAACTCCTCAGCAGCAACCACAGTACAACCTTCCAGAAAGAGACAAG
CAACTACTTTTCTCAGAATATAATTTTGAAGATCTTAGTGCCTCATTTCGGAGCCTTTATAAGTCAGTTTTTGAGCAGTCACTTAGTCAA
CAAGGTTTGATGAACATCCCTTCTGAATCTTCCCAGCAGTCCCACACTTCATGTACCTATCAGCACTCTCCCAGCAGTACAGTGAGCACT
CACCCACACAGCAACCAAAGCAGCCTGTCCAACAGTCATGGCAGTGGCCTCAACACCACAGGCAGTAATTCGGTTGCACAGGTCTCACTG
TCTCACCCCCAGATGCACACACAGCCATCTCCACATCCTCCCCATCGACCGCATGGTTTACCGCAGCATCCGCAGCGTTCCCCACACCCA
GCACCACACCCACAGCAACACAGCCAGCTCCAGTCCCCTCACCCCCAGCATCCCTCTCCACATCAACACATACAGCACCATCCGAACCAT
CAGCATCAGACGTTAACACATCAGGCACCCCCACCCCCACAACAGGTATCCTGTAATTCTGGTGTTTCAAATGATTGGTATGCGACACTT
GATATGCTAAAAGAAAGCTGTCGAATTGCCAGCAGTGTTAATTGGTCAGATGTAGACCTTTCACAGTTTCAAGGTCTGATGGAGAGTATG
AGACAGGCAGATCTCAAGAACTGGTCTTTAGACCAGGTTCAGTTTGCCGATCTTTGTTCTTCTCTTAATCAGTTCTTTACACAAACTGGC
CTTATACATTCACAGAGTAATGTTCAACAAAATGTTTGTCATGGTGCCATGCATCCAACAAAACCTTCCCAACACATTGGAACAGGAAAT
TTGTACATAGATTCTAGGCAAAATCTCCCTCCTTCAGTGATGCCACCCCCTGGTTATCCTCATATCCCACAGGCACTCAGCACTCCAGGA
ACAACGATGGCAGGCCATCACAGAGCCATGAACCAGCAGCACATGATGCCTTCCCAAGCCTTCCAGATGCGGCGTTCCCTGCCTCCAGAT
GACATCCAGGATGACTTTGATTGGGATTCAATTGTGTAGGGCTTGTTTCTGCAAGACACCAGACCCTAACGTTACCTTTCTGTGCAGTGA
AGGGAAAGGTTTAAGAGAATCCAGTTGAGAAAACAAACTTGCTAATCACTTTACCAATGTTATCAAAATTACTTTTGAAGACAATCAGAA
GGATTTTAGCTGGATAACTTACTGCTTTTATCTGACCCAAGCAAGTACTACATGTTTGTCTCCCTGCCAGCTGCCCTATGTAGCTCCTAA
CTGTTGTGTGATTTGGACGGCTTTTTGCATATTTGTGTCAGTTTGATGTTAACCACAAGTGCCAGACTGATTTTTCAGACGGAGCCTATT
TTGCTGCAAGCAGTTTATATAAAGATACATATGTGTAAATATATGTACAAAAATTACTGAAAGGCTTCAGTTTTTTCTAATTGGATTATT
ATGTCTTGAAAGTTATTGTCAGTTTTTATTCCTTGTTAGGCTATTTTCTGCAGGATGCTTTTAACTGATGTAGGAAACTGAAAGGAAATA
GATTTTTTCCAAAACCCAGTTCCCCTTATTTAATCTTTTTTAGAAATGTGGGTAATGAATTCTATCTAATAAGTCAAGGAAACCAGAATT
TGACACACTCCAACAATCCGAAGGGGCATGTTGCTCCTGAGCAGCATGAAGAACTGACCAAATTGGTTTTGATGCTTGGGGGATCATAGA
GTATTTATGTCTGCTTTTCTAAATCTGCATTATAATAGCTCTAAAATTTGTTGATTGGTAAGAAATTGGGCATTGCTTGGCTCTTTAAAC
ACATCAGTGCTTCCACATTCACCTATGTATTTATTATTCAAAAGTGTCATTTTAATATTTATTGCTACCTTCTGTGAATGCTTAGCTCCT
GTCGGGTTCATTAAGGAGAAATGTGTCTGAAAGCACAGAACTATTATTATTTTTTTCTTTTTTTGAGATGGAGTCTTGCCCTGTTGCCCA
GGCTGGAGTGCAGTGGCACGATCTCGGCTCACTGCAACCTCCGCCTCCCGGGTTCAAGCAATTCTCCTGCCTCAGCCTCCCGAGTAGCTG
GGAGTGCAGGTGCACACCGCCATGCCTGGCTGATTTTTTGTATTTTAGTAGAGATGGGGTTTCACCATGTTGCCTGGGCTGGTTGCAAAC
TCTTGAGCTCAGGCAGTCTGCCTGCCTCAGCCTCCTAGAGTGCTGGGATTACAGACATGAGCCACTGCGCCTGGCCCAGCGTTACTTTTC
TTGATAAGAATTTACAGATAAGACACTCAGAGAGACATTGTGTCATTCTCTATCATCACTCCTTTTACCATGTGAATAGATTTCTCTGTC
TTGGCATTCTTGCTGATTCAGACTTATTAGTTAAATCGGATTTTTCTGGAATTTGAATCAGATTTCATTTGGGCAACAACAGCAGGGCAG
GGTTTCTAAAGCAGGTTTCCCCACTCATCTAGGTTGTCTTGAAAGGAGGATAGAGCCACTTACAGTTTTATTTGCTTCAGTGTTTAATGT
AGATATTATGTGGCCTGCTGTTTCTGTTGTCTTGTATGTCTGTGTATGCATGACATTTGGTCCCTTTCTTTGAAATGCAGCCCCTCTTAC
GGGTTTTTTAGTGGTGGTGGTTTGTTTTGTTTCATATCATATCACAGTTTGCATGGACTGATTATCTTAGTTTTATGATAAAACTAGAAG
AAATGAGGGTTTTTTTTTAATGAATAGATTTTGAATTGATTCTTTAGACCCCCCAAAAAGTGTCAGTTCTAATGGGGAAATATATTCCAT
CAAGTCAAAGAGTAATAACTGCTCACTAGTTGCTTTTTAGCATCTCTGGTCTTATCAGCCATGCTAAATCACTTTAATTAGCCTTAGTGA
TTCTATGGTTGAGTAATCTCTACTTGAACTAAACAAACATCTTTTGTTTCTGTGTGTGTGTGCTGTGTGTGAGAGTGTGCGCGCGCGTGT
GTGTGTGTGTGTTTTAATGGAGTGTTGCCTTGAATGAATCACTGGGAAGCCAGCCATGGTAAGGGCTGGTGAGGTTGGGGAGAAAGGAAG
AGCTTTATGTTTCTCTGTTGTTTGGACCCTACTTGGCATGAAAAAGGAAGCTCAGTTCCAGCCCCTTGGATCAACGAAAATCAGAGGATT
CTGGAAAGGCAGCCAACTTGCGCCTCTTAGAAGGATCAGAGGCAAGATGAGATGGCAGCCTGCAGAGTAAATGCTTGAAAAAAGAGGGGT
GATTTTCAATGGTTTGCTTAAGTCACTGTTTTCTAGACACCAAAATAGCTGTTTTGAAACTGTTTTAATTGCTTGGGTAGCAATGTGCAC
TTTAAACAATTTGGATATTGGAATGCAGTCTCATACTGAGTGATTTGAGTAGAACCACTGATGATGATTTTATAAATTGTGTGAAGCGAA
TTTCCCATTTGGCAATCATTTACTGATTTGCAGTGATGAATATTTTTATGAGAATTTAAACTTAGCAAGAATGGCCATGGAGGCAAAGCC
TTCACCCAGACCCATCCCACTCTCCTGTGATCCAGGTGGTCCAGGAGCCCAGGACAGGCCTTTTCTGTGGGCCCTGGCCAGACAGGGTTA
CCTGGTGAGGTGCAGAGAGTCCCTCTAGTGGCCATTTTGTATGGTAGTTGCTAATGCAGAACAAGTTCTGTCTTGGGCTTAAATTGACTG
AAGACTTTAGGGGGAAAGAATAGTAAATGCATGTAAACAAATGGGGACACTCTGTTCAGGAGAATAATCCGACTGGCATTTGTGGCAGTT
TTTGAAATGTAAATGTATTCATGTGTGTTCTTGTAAATACGTGTCGCTCAGATGTCCTTTGAAGTGGGAGGGAATCAATCCGGGGATAAT
TTCAAATGGAATAGAGTATTTTGATATTGTTCATTCAGAGGGTGATGTGTACATATCTATATTGTATATATGTGATGAAAATGCATTGGC
TTTTTGTGCAGATACAACCTGCTCTCTGTACTGCTGTTGGACAGTCAGTGTTTTAATGTTTCTACAGTTTTGCTATTGCACGATTTCATA
TTTTGCCTCTATGATGAACGGCAACCATTATTTGTAACTGTTTAGTGCTGTAAAGAAATATTCCAAGTGTCATTAGGATTGTTGCTGCCA

>In-frame_ENST00000371084_ENST00000545068_TCGA-30-1891-01A_PGM1_chr1_64059405_+_FOXJ3_chr1_42660735_length(amino acids)=504AA_start in transcript=54_stop in transcript=1568
MSPVPLRRRAKRRPRVRRSPHPPCPHPRAAAASAGRPSASQVRRSDPRQQVATMVKIVTVKTQAYQDQKPGTSGLRKRVKVFQSSANYAE
NFIQSIISTVEPAQRQEATLVVGGDGRFYMKEAIQLIARIAAANGVTSHPESVSQSLTPQQQPQYNLPERDKQLLFSEYNFEDLSASFRS
LYKSVFEQSLSQQGLMNIPSESSQQSHTSCTYQHSPSSTVSTHPHSNQSSLSNSHGSGLNTTGSNSVAQVSLSHPQMHTQPSPHPPHRPH
GLPQHPQRSPHPAPHPQQHSQLQSPHPQHPSPHQHIQHHPNHQHQTLTHQAPPPPQQVSCNSGVSNDWYATLDMLKESCRIASSVNWSDV
DLSQFQGLMESMRQADLKNWSLDQVQFADLCSSLNQFFTQTGLIHSQSNVQQNVCHGAMHPTKPSQHIGTGNLYIDSRQNLPPSVMPPPG

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Fusion Gene PPI Analysis for PGM1-FOXJ3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for PGM1-FOXJ3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for PGM1-FOXJ3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgenePGM1C2752015Glycogen Storage Disease XIV8CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
HgenePGM1C0017919Glycogen Storage Disease2GENOMICS_ENGLAND
HgenePGM1C3808991NGLY1 deficiency2GENOMICS_ENGLAND
HgenePGM1C0009402Colorectal Carcinoma1CTD_human
HgenePGM1C0009404Colorectal Neoplasms1CTD_human
HgenePGM1C0019193Hepatitis, Toxic1CTD_human
HgenePGM1C0151744Myocardial Ischemia1CTD_human
HgenePGM1C0860207Drug-Induced Liver Disease1CTD_human
HgenePGM1C1262760Hepatitis, Drug-Induced1CTD_human
HgenePGM1C3658290Drug-Induced Acute Liver Injury1CTD_human
HgenePGM1C4277682Chemical and Drug Induced Liver Injury1CTD_human
HgenePGM1C4279912Chemically-Induced Liver Toxicity1CTD_human