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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:PHC3-NFKBIL1 (FusionGDB2 ID:64339)

Fusion Gene Summary for PHC3-NFKBIL1

check button Fusion gene summary
Fusion gene informationFusion gene name: PHC3-NFKBIL1
Fusion gene ID: 64339
HgeneTgene
Gene symbol

PHC3

NFKBIL1

Gene ID

80012

4795

Gene namepolyhomeotic homolog 3NFKB inhibitor like 1
SynonymsEDR3|HPH3IKBL|NFKBIL
Cytomap

3q26.2

6p21.33

Type of geneprotein-codingprotein-coding
Descriptionpolyhomeotic-like protein 3early development regulator 3early development regulatory protein 3homolog of polyhomeotic 3polyhomeotic like 3NF-kappa-B inhibitor-like protein 1I-kappa-B-like proteinikappaBLinhibitor of kappa B-like proteinnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000495893, ENST00000494943, 
ENST00000467570, ENST00000474275, 
ENST00000497658, ENST00000481639, 
ENST00000376148, ENST00000376145, 
ENST00000434332, ENST00000419122, 
ENST00000414391, ENST00000496344, 
ENST00000455376, ENST00000430501, 
ENST00000460420, ENST00000442947, 
ENST00000421396, ENST00000464328, 
ENST00000400279, ENST00000400285, 
ENST00000383500, ENST00000466313, 
ENST00000432160, ENST00000451911, 
ENST00000480619, ENST00000428467, 
ENST00000424652, ENST00000419623, 
Fusion gene scores* DoF score15 X 15 X 11=24751 X 1 X 1=1
# samples 201
** MAII scorelog2(20/2475*10)=-3.62935662007961
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(1/1*10)=3.32192809488736
Context

PubMed: PHC3 [Title/Abstract] AND NFKBIL1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointPHC3(169889161)-NFKBIL1(31515940), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneNFKBIL1

GO:0031665

negative regulation of lipopolysaccharide-mediated signaling pathway

20829348

TgeneNFKBIL1

GO:0032088

negative regulation of NF-kappaB transcription factor activity

20829348

TgeneNFKBIL1

GO:0034122

negative regulation of toll-like receptor signaling pathway

20829348

TgeneNFKBIL1

GO:0071222

cellular response to lipopolysaccharide

20829348


check buttonFusion gene breakpoints across PHC3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across NFKBIL1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4UCSTCGA-NA-A4QX-01APHC3chr3

169889161

-NFKBIL1chr6

31515940

+
ChimerDB4UCSTCGA-NA-A4QXPHC3chr3

169889161

-NFKBIL1chr6

31515940

+
ChimerDB4UCSTCGA-NA-A4QX-01APHC3chr3

169889161

-NFKBIL1chr6

31515940

+


Top

Fusion Gene ORF analysis for PHC3-NFKBIL1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000495893ENST00000376148PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
In-frameENST00000495893ENST00000376145PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000495893ENST00000434332PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000495893ENST00000419122PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000495893ENST00000414391PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000495893ENST00000496344PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000495893ENST00000455376PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000495893ENST00000430501PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000495893ENST00000460420PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000495893ENST00000442947PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000495893ENST00000421396PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000495893ENST00000464328PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000495893ENST00000400279PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000495893ENST00000400285PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000495893ENST00000383500PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000495893ENST00000466313PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000495893ENST00000432160PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000495893ENST00000451911PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000495893ENST00000480619PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000495893ENST00000428467PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000495893ENST00000424652PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000495893ENST00000419623PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
In-frameENST00000494943ENST00000376148PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
In-frameENST00000494943ENST00000376145PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000494943ENST00000434332PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000494943ENST00000419122PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000494943ENST00000414391PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000494943ENST00000496344PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000494943ENST00000455376PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000494943ENST00000430501PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000494943ENST00000460420PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000494943ENST00000442947PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000494943ENST00000421396PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000494943ENST00000464328PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000494943ENST00000400279PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000494943ENST00000400285PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000494943ENST00000383500PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000494943ENST00000466313PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000494943ENST00000432160PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000494943ENST00000451911PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000494943ENST00000480619PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000494943ENST00000428467PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000494943ENST00000424652PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000494943ENST00000419623PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
In-frameENST00000467570ENST00000376148PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
In-frameENST00000467570ENST00000376145PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000467570ENST00000434332PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000467570ENST00000419122PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000467570ENST00000414391PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000467570ENST00000496344PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000467570ENST00000455376PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000467570ENST00000430501PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000467570ENST00000460420PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000467570ENST00000442947PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000467570ENST00000421396PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000467570ENST00000464328PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000467570ENST00000400279PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000467570ENST00000400285PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000467570ENST00000383500PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000467570ENST00000466313PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000467570ENST00000432160PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000467570ENST00000451911PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000467570ENST00000480619PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000467570ENST00000428467PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000467570ENST00000424652PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000467570ENST00000419623PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
In-frameENST00000474275ENST00000376148PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
In-frameENST00000474275ENST00000376145PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000474275ENST00000434332PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000474275ENST00000419122PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000474275ENST00000414391PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000474275ENST00000496344PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000474275ENST00000455376PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000474275ENST00000430501PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000474275ENST00000460420PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000474275ENST00000442947PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000474275ENST00000421396PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000474275ENST00000464328PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000474275ENST00000400279PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000474275ENST00000400285PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000474275ENST00000383500PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000474275ENST00000466313PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000474275ENST00000432160PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000474275ENST00000451911PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000474275ENST00000480619PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000474275ENST00000428467PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000474275ENST00000424652PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
5CDS-intronENST00000474275ENST00000419623PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
intron-3CDSENST00000497658ENST00000376148PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
intron-3CDSENST00000497658ENST00000376145PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
intron-intronENST00000497658ENST00000434332PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
intron-intronENST00000497658ENST00000419122PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
intron-intronENST00000497658ENST00000414391PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
intron-intronENST00000497658ENST00000496344PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
intron-intronENST00000497658ENST00000455376PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
intron-intronENST00000497658ENST00000430501PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
intron-intronENST00000497658ENST00000460420PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
intron-intronENST00000497658ENST00000442947PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
intron-intronENST00000497658ENST00000421396PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
intron-intronENST00000497658ENST00000464328PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
intron-intronENST00000497658ENST00000400279PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
intron-intronENST00000497658ENST00000400285PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
intron-intronENST00000497658ENST00000383500PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
intron-intronENST00000497658ENST00000466313PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
intron-intronENST00000497658ENST00000432160PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
intron-intronENST00000497658ENST00000451911PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
intron-intronENST00000497658ENST00000480619PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
intron-intronENST00000497658ENST00000428467PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
intron-intronENST00000497658ENST00000424652PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
intron-intronENST00000497658ENST00000419623PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
intron-3CDSENST00000481639ENST00000376148PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
intron-3CDSENST00000481639ENST00000376145PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
intron-intronENST00000481639ENST00000434332PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
intron-intronENST00000481639ENST00000419122PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
intron-intronENST00000481639ENST00000414391PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
intron-intronENST00000481639ENST00000496344PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
intron-intronENST00000481639ENST00000455376PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
intron-intronENST00000481639ENST00000430501PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
intron-intronENST00000481639ENST00000460420PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
intron-intronENST00000481639ENST00000442947PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
intron-intronENST00000481639ENST00000421396PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
intron-intronENST00000481639ENST00000464328PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
intron-intronENST00000481639ENST00000400279PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
intron-intronENST00000481639ENST00000400285PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
intron-intronENST00000481639ENST00000383500PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
intron-intronENST00000481639ENST00000466313PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
intron-intronENST00000481639ENST00000432160PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
intron-intronENST00000481639ENST00000451911PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
intron-intronENST00000481639ENST00000480619PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
intron-intronENST00000481639ENST00000428467PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
intron-intronENST00000481639ENST00000424652PHC3chr3

169889161

-NFKBIL1chr6

31515940

+
intron-intronENST00000481639ENST00000419623PHC3chr3

169889161

-NFKBIL1chr6

31515940

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000495893PHC3chr3169889161-ENST00000376148NFKBIL1chr631515940+1753446321534500
ENST00000495893PHC3chr3169889161-ENST00000376145NFKBIL1chr631515940+1708446321489485
ENST00000494943PHC3chr3169889161-ENST00000376148NFKBIL1chr631515940+1754447691535488
ENST00000494943PHC3chr3169889161-ENST00000376145NFKBIL1chr631515940+1709447691490473
ENST00000467570PHC3chr3169889161-ENST00000376148NFKBIL1chr631515940+1755448341536500
ENST00000467570PHC3chr3169889161-ENST00000376145NFKBIL1chr631515940+1710448341491485
ENST00000474275PHC3chr3169889161-ENST00000376148NFKBIL1chr631515940+1737430641518484
ENST00000474275PHC3chr3169889161-ENST00000376145NFKBIL1chr631515940+1692430641473469

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000495893ENST00000376148PHC3chr3169889161-NFKBIL1chr631515940+0.169723380.83027655
ENST00000495893ENST00000376145PHC3chr3169889161-NFKBIL1chr631515940+0.182895990.81710404
ENST00000494943ENST00000376148PHC3chr3169889161-NFKBIL1chr631515940+0.178371440.8216285
ENST00000494943ENST00000376145PHC3chr3169889161-NFKBIL1chr631515940+0.185922150.81407785
ENST00000467570ENST00000376148PHC3chr3169889161-NFKBIL1chr631515940+0.166652750.8333472
ENST00000467570ENST00000376145PHC3chr3169889161-NFKBIL1chr631515940+0.178094520.8219055
ENST00000474275ENST00000376148PHC3chr3169889161-NFKBIL1chr631515940+0.189889580.81011045
ENST00000474275ENST00000376145PHC3chr3169889161-NFKBIL1chr631515940+0.202250780.7977493

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Fusion Genomic Features for PHC3-NFKBIL1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
PHC3chr3169889160-NFKBIL1chr631515939+1.51E-111
PHC3chr3169889160-NFKBIL1chr631515939+1.51E-111
PHC3chr3169889160-NFKBIL1chr631515939+1.51E-111
PHC3chr3169889160-NFKBIL1chr631515939+1.51E-111

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for PHC3-NFKBIL1


check button Go to

FGviewer for the breakpoints of chr3:169889161-chr6:31515940

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePHC3chr3:169889161chr6:31515940ENST00000474275-4519_26122.0187.0Compositional biasNote=Poly-Thr
HgenePHC3chr3:169889161chr6:31515940ENST00000494943-41519_26126.0984.0Compositional biasNote=Poly-Thr
HgenePHC3chr3:169889161chr6:31515940ENST00000495893-41519_26138.0996.0Compositional biasNote=Poly-Thr
TgeneNFKBIL1chr3:169889161chr6:31515940ENST000003761480464_9319.0382.0RepeatNote=ANK 1
TgeneNFKBIL1chr3:169889161chr6:31515940ENST000003761480497_13019.0382.0RepeatNote=ANK 2
TgeneNFKBIL1chr3:169889161chr6:31515940ENST000003835000464_930367.0RepeatNote=ANK 1
TgeneNFKBIL1chr3:169889161chr6:31515940ENST000003835000497_1300367.0RepeatNote=ANK 2
TgeneNFKBIL1chr3:169889161chr6:31515940ENST000004002790464_930359.0RepeatNote=ANK 1
TgeneNFKBIL1chr3:169889161chr6:31515940ENST000004002790497_1300359.0RepeatNote=ANK 2
TgeneNFKBIL1chr3:169889161chr6:31515940ENST000004002850464_930382.0RepeatNote=ANK 1
TgeneNFKBIL1chr3:169889161chr6:31515940ENST000004002850497_1300382.0RepeatNote=ANK 2
TgeneNFKBIL1chr3:169889161chr6:31515940ENST000004143910464_930367.0RepeatNote=ANK 1
TgeneNFKBIL1chr3:169889161chr6:31515940ENST000004143910497_1300367.0RepeatNote=ANK 2
TgeneNFKBIL1chr3:169889161chr6:31515940ENST000004191220464_930382.0RepeatNote=ANK 1
TgeneNFKBIL1chr3:169889161chr6:31515940ENST000004191220497_1300382.0RepeatNote=ANK 2
TgeneNFKBIL1chr3:169889161chr6:31515940ENST000004196230464_930367.0RepeatNote=ANK 1
TgeneNFKBIL1chr3:169889161chr6:31515940ENST000004196230497_1300367.0RepeatNote=ANK 2
TgeneNFKBIL1chr3:169889161chr6:31515940ENST000004213960464_930367.0RepeatNote=ANK 1
TgeneNFKBIL1chr3:169889161chr6:31515940ENST000004213960497_1300367.0RepeatNote=ANK 2
TgeneNFKBIL1chr3:169889161chr6:31515940ENST000004246520464_930382.0RepeatNote=ANK 1
TgeneNFKBIL1chr3:169889161chr6:31515940ENST000004246520497_1300382.0RepeatNote=ANK 2
TgeneNFKBIL1chr3:169889161chr6:31515940ENST000004284670464_930359.0RepeatNote=ANK 1
TgeneNFKBIL1chr3:169889161chr6:31515940ENST000004284670497_1300359.0RepeatNote=ANK 2
TgeneNFKBIL1chr3:169889161chr6:31515940ENST000004305010464_930367.0RepeatNote=ANK 1
TgeneNFKBIL1chr3:169889161chr6:31515940ENST000004305010497_1300367.0RepeatNote=ANK 2
TgeneNFKBIL1chr3:169889161chr6:31515940ENST000004321600464_930382.0RepeatNote=ANK 1
TgeneNFKBIL1chr3:169889161chr6:31515940ENST000004321600497_1300382.0RepeatNote=ANK 2
TgeneNFKBIL1chr3:169889161chr6:31515940ENST000004343320464_930359.0RepeatNote=ANK 1
TgeneNFKBIL1chr3:169889161chr6:31515940ENST000004343320497_1300359.0RepeatNote=ANK 2
TgeneNFKBIL1chr3:169889161chr6:31515940ENST000004429470464_930382.0RepeatNote=ANK 1
TgeneNFKBIL1chr3:169889161chr6:31515940ENST000004429470497_1300382.0RepeatNote=ANK 2
TgeneNFKBIL1chr3:169889161chr6:31515940ENST000004519110464_930367.0RepeatNote=ANK 1
TgeneNFKBIL1chr3:169889161chr6:31515940ENST000004519110497_1300367.0RepeatNote=ANK 2
TgeneNFKBIL1chr3:169889161chr6:31515940ENST000004553760464_930382.0RepeatNote=ANK 1
TgeneNFKBIL1chr3:169889161chr6:31515940ENST000004553760497_1300382.0RepeatNote=ANK 2

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePHC3chr3:169889161chr6:31515940ENST00000474275-45324_539122.0187.0Compositional biasNote=Gln-rich
HgenePHC3chr3:169889161chr6:31515940ENST00000474275-45346_670122.0187.0Compositional biasNote=Pro-rich
HgenePHC3chr3:169889161chr6:31515940ENST00000474275-4589_287122.0187.0Compositional biasNote=Ser-rich
HgenePHC3chr3:169889161chr6:31515940ENST00000494943-415324_539126.0984.0Compositional biasNote=Gln-rich
HgenePHC3chr3:169889161chr6:31515940ENST00000494943-415346_670126.0984.0Compositional biasNote=Pro-rich
HgenePHC3chr3:169889161chr6:31515940ENST00000494943-41589_287126.0984.0Compositional biasNote=Ser-rich
HgenePHC3chr3:169889161chr6:31515940ENST00000495893-415324_539138.0996.0Compositional biasNote=Gln-rich
HgenePHC3chr3:169889161chr6:31515940ENST00000495893-415346_670138.0996.0Compositional biasNote=Pro-rich
HgenePHC3chr3:169889161chr6:31515940ENST00000495893-41589_287138.0996.0Compositional biasNote=Ser-rich
HgenePHC3chr3:169889161chr6:31515940ENST00000497658-1419_260152.0Compositional biasNote=Poly-Thr
HgenePHC3chr3:169889161chr6:31515940ENST00000497658-14324_5390152.0Compositional biasNote=Gln-rich
HgenePHC3chr3:169889161chr6:31515940ENST00000497658-14346_6700152.0Compositional biasNote=Pro-rich
HgenePHC3chr3:169889161chr6:31515940ENST00000497658-1489_2870152.0Compositional biasNote=Ser-rich
HgenePHC3chr3:169889161chr6:31515940ENST00000474275-45919_983122.0187.0DomainSAM
HgenePHC3chr3:169889161chr6:31515940ENST00000494943-415919_983126.0984.0DomainSAM
HgenePHC3chr3:169889161chr6:31515940ENST00000495893-415919_983138.0996.0DomainSAM
HgenePHC3chr3:169889161chr6:31515940ENST00000497658-14919_9830152.0DomainSAM
HgenePHC3chr3:169889161chr6:31515940ENST00000474275-45691_720122.0187.0MotifNote=HD1
HgenePHC3chr3:169889161chr6:31515940ENST00000494943-415691_720126.0984.0MotifNote=HD1
HgenePHC3chr3:169889161chr6:31515940ENST00000495893-415691_720138.0996.0MotifNote=HD1
HgenePHC3chr3:169889161chr6:31515940ENST00000497658-14691_7200152.0MotifNote=HD1
HgenePHC3chr3:169889161chr6:31515940ENST00000474275-45776_810122.0187.0Zinc fingerFCS-type
HgenePHC3chr3:169889161chr6:31515940ENST00000494943-415776_810126.0984.0Zinc fingerFCS-type
HgenePHC3chr3:169889161chr6:31515940ENST00000495893-415776_810138.0996.0Zinc fingerFCS-type
HgenePHC3chr3:169889161chr6:31515940ENST00000497658-14776_8100152.0Zinc fingerFCS-type


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Fusion Gene Sequence for PHC3-NFKBIL1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000495893_ENST00000376148_TCGA-NA-A4QX-01A_PHC3_chr3_169889161_-_NFKBIL1_chr6_31515940_length(transcript)=1753nt_BP=446nt
GCGCAGCCCATGTTAGTGATGGAGGAGAGAAGATGGCGGAAGCGGAATTTAAGGACCATAGTACAGCTATGGATACTGAACCAAACCCGG
GAACATCTTCTGTGTCAACAACAACCAGCAGTACCACCACCACCACCATCACCACTTCCTCCTCTCGAATGCAGCAGCCACAGATCTCTG
TCTACAGTGGTTCAGACCGACATGCTGTACAGGTAATTCAACAGGCATTGCATCGGCCCCCCAGCTCAGCTGCTCAGTACCTTCAGCAAA
TGTATGCAGCCCAACAACAGCACTTGATGCTGCATACTGCAGCTCTTCAGCAGCAGCATTTAAGCAGCTCCCAGCTTCAGAGCCTTGCTG
CTGTTCAGGCAAGTTTGTCCAGTGGAAGACCATCTACATCTCCCACAGGAAGTGTCACACAGCAGTCAAGTATGTCCCAAACGTCTCCCA
AGAGTTCCATGGCCTCCACTTCCCGCCGCCAACGCCGAGAACGTCGCTTTCGTCGTTACTTGTCTGCAGGACGGCTGGTCCGGGCCCAGG
CCCTCCTCCAGCGACACCCAGGCCTCGATGTAGATGCTGGGCAGCCCCCACCACTGCACCGGGCCTGTGCCCGCCACGATGCCCCTGCCC
TGTGCCTGCTGCTTCGGCTCGGGGCTGACCCTGCCCACCAGGACCGCCATGGGGACACGGCACTGCATGCTGCTGCCCGCCAGGGCCCAG
ATGCCTACACCGATTTCTTCCTCCCGCTGCTAAGCCGCTGTCCCTCCGCCATGGGAATAAAGAATAAGGATGGGGAGACCCCTGGCCAAA
TTTTGGGCTGGGGACCCCCCTGGGATTCTGCTGAAGAGGAGGAAGAAGATGATGCCTCCAAGGAGCGGGAATGGAGACAGAAGCTCCAGG
GTGAGCTGGAGGACGAGTGGCAGGAAGTCATGGGGAGGTTTGAAGGTGATGCCTCCCATGAAACCCAGGAACCTGAGTCCTTCTCAGCCT
GGTCAGATCGCCTGGCCCGGGAACATGCCCAGAAGTGCCAGCAGCAGCAGCGAGAAGCAGAGGGATCCCGTCGACCCCCACGTGCTGAGG
GCTCCAGCCAGAGCTGGCGACAGCAGGAGGAGGAGCAGCGGCTCTTCAGGGAGCGAGCCCGGGCCAAGGAGGAAGAGCTGCGTGAGAGCC
GAGCCAGGAGGGCGCAGGAGGCTCTAGGGGACCGAGAACCCAAGCCAACCAGGGCCGGGCCCAGGGAAGAGCACCCCAGAGGAGCGGGGA
GGGGCAGCCTCTGGCGATTTGGTGATGTGCCCTGGCCCTGCCCTGGGGGAGGGGACCCAGAGGCCATGGCTGCAGCCCTGGTGGCCAGGG
GCCCCCCTTTGGAGGAACAGGGGGCTCTGAGGAGGTACTTGAGGGTCCAGCAGGTCCGCTGGCACCCTGACCGCTTCCTGCAGCGATTCC
GAAGCCAGATTGAGACCTGGGAGCTGGGCCGTGTGATGGGAGCAGTGACAGCCCTTTCTCAGGCCCTGAATCGCCATGCAGAGGCCCTCA
AGTGACCCTAGGGAAGAAGCAAGAAACTTCGGGGCTGCAGCCTCAGGATGAGGCAGAAGGAAGGGTAAGGGAAAGGATGGGGACCACAAG
GAAGAGCCAGGTGCTGCTCAGCAGAGGATATGGGTGGGAGCGAAAGTTGTAACAAGTGGGGGTGGGGGGTGCGGGCCGCCACCACTGCTC

>In-frame_ENST00000495893_ENST00000376148_TCGA-NA-A4QX-01A_PHC3_chr3_169889161_-_NFKBIL1_chr6_31515940_length(amino acids)=500AA_start in transcript=32_stop in transcript=1534
MAEAEFKDHSTAMDTEPNPGTSSVSTTTSSTTTTTITTSSSRMQQPQISVYSGSDRHAVQVIQQALHRPPSSAAQYLQQMYAAQQQHLML
HTAALQQQHLSSSQLQSLAAVQASLSSGRPSTSPTGSVTQQSSMSQTSPKSSMASTSRRQRRERRFRRYLSAGRLVRAQALLQRHPGLDV
DAGQPPPLHRACARHDAPALCLLLRLGADPAHQDRHGDTALHAAARQGPDAYTDFFLPLLSRCPSAMGIKNKDGETPGQILGWGPPWDSA
EEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQEE
EQRLFRERARAKEEELRESRARRAQEALGDREPKPTRAGPREEHPRGAGRGSLWRFGDVPWPCPGGGDPEAMAAALVARGPPLEEQGALR

--------------------------------------------------------------
>In-frame_ENST00000495893_ENST00000376145_TCGA-NA-A4QX-01A_PHC3_chr3_169889161_-_NFKBIL1_chr6_31515940_length(transcript)=1708nt_BP=446nt
GCGCAGCCCATGTTAGTGATGGAGGAGAGAAGATGGCGGAAGCGGAATTTAAGGACCATAGTACAGCTATGGATACTGAACCAAACCCGG
GAACATCTTCTGTGTCAACAACAACCAGCAGTACCACCACCACCACCATCACCACTTCCTCCTCTCGAATGCAGCAGCCACAGATCTCTG
TCTACAGTGGTTCAGACCGACATGCTGTACAGGTAATTCAACAGGCATTGCATCGGCCCCCCAGCTCAGCTGCTCAGTACCTTCAGCAAA
TGTATGCAGCCCAACAACAGCACTTGATGCTGCATACTGCAGCTCTTCAGCAGCAGCATTTAAGCAGCTCCCAGCTTCAGAGCCTTGCTG
CTGTTCAGGCAAGTTTGTCCAGTGGAAGACCATCTACATCTCCCACAGGAAGTGTCACACAGCAGTCAAGTATGTCCCAAACGTCTCCCA
AGAGTTCCATGGCCTCCACTTCCCGCCGCCAACGCCGAGAACGTCGCTTTCGTCGTTACTTGTCTGCAGGACGGCTGGTCCGGGCCCAGG
CCCTCCTCCAGCGACACCCAGGCCTCGATGTAGATGCTGGGCAGCCCCCACCACTGCACCGGGCCTGTGCCCGCCACGATGCCCCTGCCC
TGTGCCTGCTGCTTCGGCTCGGGGCTGACCCTGCCCACCAGGACCGCCATGGGGACACGGCACTGCATGCTGCTGCCCGCCAGGGCCCAG
ATGCCTACACCGATTTCTTCCTCCCGCTGCTAAGCCGCTGTCCCTCCGCCATGGGAATAAAGAATAAGGATGGGGAGACCCCTGGCCAAA
TTTTGGGCTGGGGACCCCCCTGGGATTCTGCTGAAGAGGAGGAAGAAGATGATGCCTCCAAGGAGCGGGAATGGAGACAGAAGCTCCAGG
GTGATGCCTCCCATGAAACCCAGGAACCTGAGTCCTTCTCAGCCTGGTCAGATCGCCTGGCCCGGGAACATGCCCAGAAGTGCCAGCAGC
AGCAGCGAGAAGCAGAGGGATCCCGTCGACCCCCACGTGCTGAGGGCTCCAGCCAGAGCTGGCGACAGCAGGAGGAGGAGCAGCGGCTCT
TCAGGGAGCGAGCCCGGGCCAAGGAGGAAGAGCTGCGTGAGAGCCGAGCCAGGAGGGCGCAGGAGGCTCTAGGGGACCGAGAACCCAAGC
CAACCAGGGCCGGGCCCAGGGAAGAGCACCCCAGAGGAGCGGGGAGGGGCAGCCTCTGGCGATTTGGTGATGTGCCCTGGCCCTGCCCTG
GGGGAGGGGACCCAGAGGCCATGGCTGCAGCCCTGGTGGCCAGGGGCCCCCCTTTGGAGGAACAGGGGGCTCTGAGGAGGTACTTGAGGG
TCCAGCAGGTCCGCTGGCACCCTGACCGCTTCCTGCAGCGATTCCGAAGCCAGATTGAGACCTGGGAGCTGGGCCGTGTGATGGGAGCAG
TGACAGCCCTTTCTCAGGCCCTGAATCGCCATGCAGAGGCCCTCAAGTGACCCTAGGGAAGAAGCAAGAAACTTCGGGGCTGCAGCCTCA
GGATGAGGCAGAAGGAAGGGTAAGGGAAAGGATGGGGACCACAAGGAAGAGCCAGGTGCTGCTCAGCAGAGGATATGGGTGGGAGCGAAA

>In-frame_ENST00000495893_ENST00000376145_TCGA-NA-A4QX-01A_PHC3_chr3_169889161_-_NFKBIL1_chr6_31515940_length(amino acids)=485AA_start in transcript=32_stop in transcript=1489
MAEAEFKDHSTAMDTEPNPGTSSVSTTTSSTTTTTITTSSSRMQQPQISVYSGSDRHAVQVIQQALHRPPSSAAQYLQQMYAAQQQHLML
HTAALQQQHLSSSQLQSLAAVQASLSSGRPSTSPTGSVTQQSSMSQTSPKSSMASTSRRQRRERRFRRYLSAGRLVRAQALLQRHPGLDV
DAGQPPPLHRACARHDAPALCLLLRLGADPAHQDRHGDTALHAAARQGPDAYTDFFLPLLSRCPSAMGIKNKDGETPGQILGWGPPWDSA
EEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEE
LRESRARRAQEALGDREPKPTRAGPREEHPRGAGRGSLWRFGDVPWPCPGGGDPEAMAAALVARGPPLEEQGALRRYLRVQQVRWHPDRF

--------------------------------------------------------------
>In-frame_ENST00000494943_ENST00000376148_TCGA-NA-A4QX-01A_PHC3_chr3_169889161_-_NFKBIL1_chr6_31515940_length(transcript)=1754nt_BP=447nt
AGTGATGGAGGAGAGAAGATGGCGGAAGCGGAGTGAGTGACTAGATGATTTAAGGACCATAGTACAGCTATGGATACTGAACCAAACCCG
GGAACATCTTCTGTGTCAACAACAACCAGCAGTACCACCACCACCACCATCACCACTTCCTCCTCTCGAATGCAGCAGCCACAGATCTCT
GTCTACAGTGGTTCAGACCGACATGCTGTACAGGTAATTCAACAGGCATTGCATCGGCCCCCCAGCTCAGCTGCTCAGTACCTTCAGCAA
ATGTATGCAGCCCAACAACAGCACTTGATGCTGCATACTGCAGCTCTTCAGCAGCAGCATTTAAGCAGCTCCCAGCTTCAGAGCCTTGCT
GCTGTTCAGGCAAGTTTGTCCAGTGGAAGACCATCTACATCTCCCACAGGAAGTGTCACACAGCAGTCAAGTATGTCCCAAACGTCTCCC
AAGAGTTCCATGGCCTCCACTTCCCGCCGCCAACGCCGAGAACGTCGCTTTCGTCGTTACTTGTCTGCAGGACGGCTGGTCCGGGCCCAG
GCCCTCCTCCAGCGACACCCAGGCCTCGATGTAGATGCTGGGCAGCCCCCACCACTGCACCGGGCCTGTGCCCGCCACGATGCCCCTGCC
CTGTGCCTGCTGCTTCGGCTCGGGGCTGACCCTGCCCACCAGGACCGCCATGGGGACACGGCACTGCATGCTGCTGCCCGCCAGGGCCCA
GATGCCTACACCGATTTCTTCCTCCCGCTGCTAAGCCGCTGTCCCTCCGCCATGGGAATAAAGAATAAGGATGGGGAGACCCCTGGCCAA
ATTTTGGGCTGGGGACCCCCCTGGGATTCTGCTGAAGAGGAGGAAGAAGATGATGCCTCCAAGGAGCGGGAATGGAGACAGAAGCTCCAG
GGTGAGCTGGAGGACGAGTGGCAGGAAGTCATGGGGAGGTTTGAAGGTGATGCCTCCCATGAAACCCAGGAACCTGAGTCCTTCTCAGCC
TGGTCAGATCGCCTGGCCCGGGAACATGCCCAGAAGTGCCAGCAGCAGCAGCGAGAAGCAGAGGGATCCCGTCGACCCCCACGTGCTGAG
GGCTCCAGCCAGAGCTGGCGACAGCAGGAGGAGGAGCAGCGGCTCTTCAGGGAGCGAGCCCGGGCCAAGGAGGAAGAGCTGCGTGAGAGC
CGAGCCAGGAGGGCGCAGGAGGCTCTAGGGGACCGAGAACCCAAGCCAACCAGGGCCGGGCCCAGGGAAGAGCACCCCAGAGGAGCGGGG
AGGGGCAGCCTCTGGCGATTTGGTGATGTGCCCTGGCCCTGCCCTGGGGGAGGGGACCCAGAGGCCATGGCTGCAGCCCTGGTGGCCAGG
GGCCCCCCTTTGGAGGAACAGGGGGCTCTGAGGAGGTACTTGAGGGTCCAGCAGGTCCGCTGGCACCCTGACCGCTTCCTGCAGCGATTC
CGAAGCCAGATTGAGACCTGGGAGCTGGGCCGTGTGATGGGAGCAGTGACAGCCCTTTCTCAGGCCCTGAATCGCCATGCAGAGGCCCTC
AAGTGACCCTAGGGAAGAAGCAAGAAACTTCGGGGCTGCAGCCTCAGGATGAGGCAGAAGGAAGGGTAAGGGAAAGGATGGGGACCACAA
GGAAGAGCCAGGTGCTGCTCAGCAGAGGATATGGGTGGGAGCGAAAGTTGTAACAAGTGGGGGTGGGGGGTGCGGGCCGCCACCACTGCT

>In-frame_ENST00000494943_ENST00000376148_TCGA-NA-A4QX-01A_PHC3_chr3_169889161_-_NFKBIL1_chr6_31515940_length(amino acids)=488AA_start in transcript=69_stop in transcript=1535
MDTEPNPGTSSVSTTTSSTTTTTITTSSSRMQQPQISVYSGSDRHAVQVIQQALHRPPSSAAQYLQQMYAAQQQHLMLHTAALQQQHLSS
SQLQSLAAVQASLSSGRPSTSPTGSVTQQSSMSQTSPKSSMASTSRRQRRERRFRRYLSAGRLVRAQALLQRHPGLDVDAGQPPPLHRAC
ARHDAPALCLLLRLGADPAHQDRHGDTALHAAARQGPDAYTDFFLPLLSRCPSAMGIKNKDGETPGQILGWGPPWDSAEEEEEDDASKER
EWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAK
EEELRESRARRAQEALGDREPKPTRAGPREEHPRGAGRGSLWRFGDVPWPCPGGGDPEAMAAALVARGPPLEEQGALRRYLRVQQVRWHP

--------------------------------------------------------------
>In-frame_ENST00000494943_ENST00000376145_TCGA-NA-A4QX-01A_PHC3_chr3_169889161_-_NFKBIL1_chr6_31515940_length(transcript)=1709nt_BP=447nt
AGTGATGGAGGAGAGAAGATGGCGGAAGCGGAGTGAGTGACTAGATGATTTAAGGACCATAGTACAGCTATGGATACTGAACCAAACCCG
GGAACATCTTCTGTGTCAACAACAACCAGCAGTACCACCACCACCACCATCACCACTTCCTCCTCTCGAATGCAGCAGCCACAGATCTCT
GTCTACAGTGGTTCAGACCGACATGCTGTACAGGTAATTCAACAGGCATTGCATCGGCCCCCCAGCTCAGCTGCTCAGTACCTTCAGCAA
ATGTATGCAGCCCAACAACAGCACTTGATGCTGCATACTGCAGCTCTTCAGCAGCAGCATTTAAGCAGCTCCCAGCTTCAGAGCCTTGCT
GCTGTTCAGGCAAGTTTGTCCAGTGGAAGACCATCTACATCTCCCACAGGAAGTGTCACACAGCAGTCAAGTATGTCCCAAACGTCTCCC
AAGAGTTCCATGGCCTCCACTTCCCGCCGCCAACGCCGAGAACGTCGCTTTCGTCGTTACTTGTCTGCAGGACGGCTGGTCCGGGCCCAG
GCCCTCCTCCAGCGACACCCAGGCCTCGATGTAGATGCTGGGCAGCCCCCACCACTGCACCGGGCCTGTGCCCGCCACGATGCCCCTGCC
CTGTGCCTGCTGCTTCGGCTCGGGGCTGACCCTGCCCACCAGGACCGCCATGGGGACACGGCACTGCATGCTGCTGCCCGCCAGGGCCCA
GATGCCTACACCGATTTCTTCCTCCCGCTGCTAAGCCGCTGTCCCTCCGCCATGGGAATAAAGAATAAGGATGGGGAGACCCCTGGCCAA
ATTTTGGGCTGGGGACCCCCCTGGGATTCTGCTGAAGAGGAGGAAGAAGATGATGCCTCCAAGGAGCGGGAATGGAGACAGAAGCTCCAG
GGTGATGCCTCCCATGAAACCCAGGAACCTGAGTCCTTCTCAGCCTGGTCAGATCGCCTGGCCCGGGAACATGCCCAGAAGTGCCAGCAG
CAGCAGCGAGAAGCAGAGGGATCCCGTCGACCCCCACGTGCTGAGGGCTCCAGCCAGAGCTGGCGACAGCAGGAGGAGGAGCAGCGGCTC
TTCAGGGAGCGAGCCCGGGCCAAGGAGGAAGAGCTGCGTGAGAGCCGAGCCAGGAGGGCGCAGGAGGCTCTAGGGGACCGAGAACCCAAG
CCAACCAGGGCCGGGCCCAGGGAAGAGCACCCCAGAGGAGCGGGGAGGGGCAGCCTCTGGCGATTTGGTGATGTGCCCTGGCCCTGCCCT
GGGGGAGGGGACCCAGAGGCCATGGCTGCAGCCCTGGTGGCCAGGGGCCCCCCTTTGGAGGAACAGGGGGCTCTGAGGAGGTACTTGAGG
GTCCAGCAGGTCCGCTGGCACCCTGACCGCTTCCTGCAGCGATTCCGAAGCCAGATTGAGACCTGGGAGCTGGGCCGTGTGATGGGAGCA
GTGACAGCCCTTTCTCAGGCCCTGAATCGCCATGCAGAGGCCCTCAAGTGACCCTAGGGAAGAAGCAAGAAACTTCGGGGCTGCAGCCTC
AGGATGAGGCAGAAGGAAGGGTAAGGGAAAGGATGGGGACCACAAGGAAGAGCCAGGTGCTGCTCAGCAGAGGATATGGGTGGGAGCGAA

>In-frame_ENST00000494943_ENST00000376145_TCGA-NA-A4QX-01A_PHC3_chr3_169889161_-_NFKBIL1_chr6_31515940_length(amino acids)=473AA_start in transcript=69_stop in transcript=1490
MDTEPNPGTSSVSTTTSSTTTTTITTSSSRMQQPQISVYSGSDRHAVQVIQQALHRPPSSAAQYLQQMYAAQQQHLMLHTAALQQQHLSS
SQLQSLAAVQASLSSGRPSTSPTGSVTQQSSMSQTSPKSSMASTSRRQRRERRFRRYLSAGRLVRAQALLQRHPGLDVDAGQPPPLHRAC
ARHDAPALCLLLRLGADPAHQDRHGDTALHAAARQGPDAYTDFFLPLLSRCPSAMGIKNKDGETPGQILGWGPPWDSAEEEEEDDASKER
EWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEA
LGDREPKPTRAGPREEHPRGAGRGSLWRFGDVPWPCPGGGDPEAMAAALVARGPPLEEQGALRRYLRVQQVRWHPDRFLQRFRSQIETWE

--------------------------------------------------------------
>In-frame_ENST00000467570_ENST00000376148_TCGA-NA-A4QX-01A_PHC3_chr3_169889161_-_NFKBIL1_chr6_31515940_length(transcript)=1755nt_BP=448nt
ATGCGCAGCCCATGTTAGTGATGGAGGAGAGAAGATGGCGGAAGCGGAATTTAAGGACCATAGTACAGCTATGGATACTGAACCAAACCC
GGGAACATCTTCTGTGTCAACAACAACCAGCAGTACCACCACCACCACCATCACCACTTCCTCCTCTCGAATGCAGCAGCCACAGATCTC
TGTCTACAGTGGTTCAGACCGACATGCTGTACAGGTAATTCAACAGGCATTGCATCGGCCCCCCAGCTCAGCTGCTCAGTACCTTCAGCA
AATGTATGCAGCCCAACAACAGCACTTGATGCTGCATACTGCAGCTCTTCAGCAGCAGCATTTAAGCAGCTCCCAGCTTCAGAGCCTTGC
TGCTGTTCAGGCAAGTTTGTCCAGTGGAAGACCATCTACATCTCCCACAGGAAGTGTCACACAGCAGTCAAGTATGTCCCAAACGTCTCC
CAAGAGTTCCATGGCCTCCACTTCCCGCCGCCAACGCCGAGAACGTCGCTTTCGTCGTTACTTGTCTGCAGGACGGCTGGTCCGGGCCCA
GGCCCTCCTCCAGCGACACCCAGGCCTCGATGTAGATGCTGGGCAGCCCCCACCACTGCACCGGGCCTGTGCCCGCCACGATGCCCCTGC
CCTGTGCCTGCTGCTTCGGCTCGGGGCTGACCCTGCCCACCAGGACCGCCATGGGGACACGGCACTGCATGCTGCTGCCCGCCAGGGCCC
AGATGCCTACACCGATTTCTTCCTCCCGCTGCTAAGCCGCTGTCCCTCCGCCATGGGAATAAAGAATAAGGATGGGGAGACCCCTGGCCA
AATTTTGGGCTGGGGACCCCCCTGGGATTCTGCTGAAGAGGAGGAAGAAGATGATGCCTCCAAGGAGCGGGAATGGAGACAGAAGCTCCA
GGGTGAGCTGGAGGACGAGTGGCAGGAAGTCATGGGGAGGTTTGAAGGTGATGCCTCCCATGAAACCCAGGAACCTGAGTCCTTCTCAGC
CTGGTCAGATCGCCTGGCCCGGGAACATGCCCAGAAGTGCCAGCAGCAGCAGCGAGAAGCAGAGGGATCCCGTCGACCCCCACGTGCTGA
GGGCTCCAGCCAGAGCTGGCGACAGCAGGAGGAGGAGCAGCGGCTCTTCAGGGAGCGAGCCCGGGCCAAGGAGGAAGAGCTGCGTGAGAG
CCGAGCCAGGAGGGCGCAGGAGGCTCTAGGGGACCGAGAACCCAAGCCAACCAGGGCCGGGCCCAGGGAAGAGCACCCCAGAGGAGCGGG
GAGGGGCAGCCTCTGGCGATTTGGTGATGTGCCCTGGCCCTGCCCTGGGGGAGGGGACCCAGAGGCCATGGCTGCAGCCCTGGTGGCCAG
GGGCCCCCCTTTGGAGGAACAGGGGGCTCTGAGGAGGTACTTGAGGGTCCAGCAGGTCCGCTGGCACCCTGACCGCTTCCTGCAGCGATT
CCGAAGCCAGATTGAGACCTGGGAGCTGGGCCGTGTGATGGGAGCAGTGACAGCCCTTTCTCAGGCCCTGAATCGCCATGCAGAGGCCCT
CAAGTGACCCTAGGGAAGAAGCAAGAAACTTCGGGGCTGCAGCCTCAGGATGAGGCAGAAGGAAGGGTAAGGGAAAGGATGGGGACCACA
AGGAAGAGCCAGGTGCTGCTCAGCAGAGGATATGGGTGGGAGCGAAAGTTGTAACAAGTGGGGGTGGGGGGTGCGGGCCGCCACCACTGC

>In-frame_ENST00000467570_ENST00000376148_TCGA-NA-A4QX-01A_PHC3_chr3_169889161_-_NFKBIL1_chr6_31515940_length(amino acids)=500AA_start in transcript=34_stop in transcript=1536
MAEAEFKDHSTAMDTEPNPGTSSVSTTTSSTTTTTITTSSSRMQQPQISVYSGSDRHAVQVIQQALHRPPSSAAQYLQQMYAAQQQHLML
HTAALQQQHLSSSQLQSLAAVQASLSSGRPSTSPTGSVTQQSSMSQTSPKSSMASTSRRQRRERRFRRYLSAGRLVRAQALLQRHPGLDV
DAGQPPPLHRACARHDAPALCLLLRLGADPAHQDRHGDTALHAAARQGPDAYTDFFLPLLSRCPSAMGIKNKDGETPGQILGWGPPWDSA
EEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQEE
EQRLFRERARAKEEELRESRARRAQEALGDREPKPTRAGPREEHPRGAGRGSLWRFGDVPWPCPGGGDPEAMAAALVARGPPLEEQGALR

--------------------------------------------------------------
>In-frame_ENST00000467570_ENST00000376145_TCGA-NA-A4QX-01A_PHC3_chr3_169889161_-_NFKBIL1_chr6_31515940_length(transcript)=1710nt_BP=448nt
ATGCGCAGCCCATGTTAGTGATGGAGGAGAGAAGATGGCGGAAGCGGAATTTAAGGACCATAGTACAGCTATGGATACTGAACCAAACCC
GGGAACATCTTCTGTGTCAACAACAACCAGCAGTACCACCACCACCACCATCACCACTTCCTCCTCTCGAATGCAGCAGCCACAGATCTC
TGTCTACAGTGGTTCAGACCGACATGCTGTACAGGTAATTCAACAGGCATTGCATCGGCCCCCCAGCTCAGCTGCTCAGTACCTTCAGCA
AATGTATGCAGCCCAACAACAGCACTTGATGCTGCATACTGCAGCTCTTCAGCAGCAGCATTTAAGCAGCTCCCAGCTTCAGAGCCTTGC
TGCTGTTCAGGCAAGTTTGTCCAGTGGAAGACCATCTACATCTCCCACAGGAAGTGTCACACAGCAGTCAAGTATGTCCCAAACGTCTCC
CAAGAGTTCCATGGCCTCCACTTCCCGCCGCCAACGCCGAGAACGTCGCTTTCGTCGTTACTTGTCTGCAGGACGGCTGGTCCGGGCCCA
GGCCCTCCTCCAGCGACACCCAGGCCTCGATGTAGATGCTGGGCAGCCCCCACCACTGCACCGGGCCTGTGCCCGCCACGATGCCCCTGC
CCTGTGCCTGCTGCTTCGGCTCGGGGCTGACCCTGCCCACCAGGACCGCCATGGGGACACGGCACTGCATGCTGCTGCCCGCCAGGGCCC
AGATGCCTACACCGATTTCTTCCTCCCGCTGCTAAGCCGCTGTCCCTCCGCCATGGGAATAAAGAATAAGGATGGGGAGACCCCTGGCCA
AATTTTGGGCTGGGGACCCCCCTGGGATTCTGCTGAAGAGGAGGAAGAAGATGATGCCTCCAAGGAGCGGGAATGGAGACAGAAGCTCCA
GGGTGATGCCTCCCATGAAACCCAGGAACCTGAGTCCTTCTCAGCCTGGTCAGATCGCCTGGCCCGGGAACATGCCCAGAAGTGCCAGCA
GCAGCAGCGAGAAGCAGAGGGATCCCGTCGACCCCCACGTGCTGAGGGCTCCAGCCAGAGCTGGCGACAGCAGGAGGAGGAGCAGCGGCT
CTTCAGGGAGCGAGCCCGGGCCAAGGAGGAAGAGCTGCGTGAGAGCCGAGCCAGGAGGGCGCAGGAGGCTCTAGGGGACCGAGAACCCAA
GCCAACCAGGGCCGGGCCCAGGGAAGAGCACCCCAGAGGAGCGGGGAGGGGCAGCCTCTGGCGATTTGGTGATGTGCCCTGGCCCTGCCC
TGGGGGAGGGGACCCAGAGGCCATGGCTGCAGCCCTGGTGGCCAGGGGCCCCCCTTTGGAGGAACAGGGGGCTCTGAGGAGGTACTTGAG
GGTCCAGCAGGTCCGCTGGCACCCTGACCGCTTCCTGCAGCGATTCCGAAGCCAGATTGAGACCTGGGAGCTGGGCCGTGTGATGGGAGC
AGTGACAGCCCTTTCTCAGGCCCTGAATCGCCATGCAGAGGCCCTCAAGTGACCCTAGGGAAGAAGCAAGAAACTTCGGGGCTGCAGCCT
CAGGATGAGGCAGAAGGAAGGGTAAGGGAAAGGATGGGGACCACAAGGAAGAGCCAGGTGCTGCTCAGCAGAGGATATGGGTGGGAGCGA
AAGTTGTAACAAGTGGGGGTGGGGGGTGCGGGCCGCCACCACTGCTCCTTGACTCTGCCGTTTCCTAATAAGACCTGGTTCCACATCTCA

>In-frame_ENST00000467570_ENST00000376145_TCGA-NA-A4QX-01A_PHC3_chr3_169889161_-_NFKBIL1_chr6_31515940_length(amino acids)=485AA_start in transcript=34_stop in transcript=1491
MAEAEFKDHSTAMDTEPNPGTSSVSTTTSSTTTTTITTSSSRMQQPQISVYSGSDRHAVQVIQQALHRPPSSAAQYLQQMYAAQQQHLML
HTAALQQQHLSSSQLQSLAAVQASLSSGRPSTSPTGSVTQQSSMSQTSPKSSMASTSRRQRRERRFRRYLSAGRLVRAQALLQRHPGLDV
DAGQPPPLHRACARHDAPALCLLLRLGADPAHQDRHGDTALHAAARQGPDAYTDFFLPLLSRCPSAMGIKNKDGETPGQILGWGPPWDSA
EEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEE
LRESRARRAQEALGDREPKPTRAGPREEHPRGAGRGSLWRFGDVPWPCPGGGDPEAMAAALVARGPPLEEQGALRRYLRVQQVRWHPDRF

--------------------------------------------------------------
>In-frame_ENST00000474275_ENST00000376148_TCGA-NA-A4QX-01A_PHC3_chr3_169889161_-_NFKBIL1_chr6_31515940_length(transcript)=1737nt_BP=430nt
TGGAGGAGAGAAGATGGCGGAAGCGGAGTGAGTGACTAGATGATTTAAGGACCATAGTACAGCTATGGATACTGAACCAAACCCGGGAAC
ATCTTCTGTGTCAACAACAACCAGCAGTACCACCACCACCACCATCACCACTTCCTCCTCTCGAATGCAGCAGCCACAGATCTCTGTCTA
CAGTGGTTCAGACCGACATGCTGTACAGGCATTGCATCGGCCCCCCAGCTCAGCTGCTCAGTACCTTCAGCAAATGTATGCAGCCCAACA
ACAGCACTTGATGCTGCATACTGCAGCTCTTCAGCAGCAGCATTTAAGCAGCTCCCAGCTTCAGAGCCTTGCTGCTGTTCAGGCAAGTTT
GTCCAGTGGAAGACCATCTACATCTCCCACAGGAAGTGTCACACAGCAGTCAAGTATGTCCCAAACGTCTCCCAAGAGTTCCATGGCCTC
CACTTCCCGCCGCCAACGCCGAGAACGTCGCTTTCGTCGTTACTTGTCTGCAGGACGGCTGGTCCGGGCCCAGGCCCTCCTCCAGCGACA
CCCAGGCCTCGATGTAGATGCTGGGCAGCCCCCACCACTGCACCGGGCCTGTGCCCGCCACGATGCCCCTGCCCTGTGCCTGCTGCTTCG
GCTCGGGGCTGACCCTGCCCACCAGGACCGCCATGGGGACACGGCACTGCATGCTGCTGCCCGCCAGGGCCCAGATGCCTACACCGATTT
CTTCCTCCCGCTGCTAAGCCGCTGTCCCTCCGCCATGGGAATAAAGAATAAGGATGGGGAGACCCCTGGCCAAATTTTGGGCTGGGGACC
CCCCTGGGATTCTGCTGAAGAGGAGGAAGAAGATGATGCCTCCAAGGAGCGGGAATGGAGACAGAAGCTCCAGGGTGAGCTGGAGGACGA
GTGGCAGGAAGTCATGGGGAGGTTTGAAGGTGATGCCTCCCATGAAACCCAGGAACCTGAGTCCTTCTCAGCCTGGTCAGATCGCCTGGC
CCGGGAACATGCCCAGAAGTGCCAGCAGCAGCAGCGAGAAGCAGAGGGATCCCGTCGACCCCCACGTGCTGAGGGCTCCAGCCAGAGCTG
GCGACAGCAGGAGGAGGAGCAGCGGCTCTTCAGGGAGCGAGCCCGGGCCAAGGAGGAAGAGCTGCGTGAGAGCCGAGCCAGGAGGGCGCA
GGAGGCTCTAGGGGACCGAGAACCCAAGCCAACCAGGGCCGGGCCCAGGGAAGAGCACCCCAGAGGAGCGGGGAGGGGCAGCCTCTGGCG
ATTTGGTGATGTGCCCTGGCCCTGCCCTGGGGGAGGGGACCCAGAGGCCATGGCTGCAGCCCTGGTGGCCAGGGGCCCCCCTTTGGAGGA
ACAGGGGGCTCTGAGGAGGTACTTGAGGGTCCAGCAGGTCCGCTGGCACCCTGACCGCTTCCTGCAGCGATTCCGAAGCCAGATTGAGAC
CTGGGAGCTGGGCCGTGTGATGGGAGCAGTGACAGCCCTTTCTCAGGCCCTGAATCGCCATGCAGAGGCCCTCAAGTGACCCTAGGGAAG
AAGCAAGAAACTTCGGGGCTGCAGCCTCAGGATGAGGCAGAAGGAAGGGTAAGGGAAAGGATGGGGACCACAAGGAAGAGCCAGGTGCTG
CTCAGCAGAGGATATGGGTGGGAGCGAAAGTTGTAACAAGTGGGGGTGGGGGGTGCGGGCCGCCACCACTGCTCCTTGACTCTGCCGTTT

>In-frame_ENST00000474275_ENST00000376148_TCGA-NA-A4QX-01A_PHC3_chr3_169889161_-_NFKBIL1_chr6_31515940_length(amino acids)=484AA_start in transcript=64_stop in transcript=1518
MDTEPNPGTSSVSTTTSSTTTTTITTSSSRMQQPQISVYSGSDRHAVQALHRPPSSAAQYLQQMYAAQQQHLMLHTAALQQQHLSSSQLQ
SLAAVQASLSSGRPSTSPTGSVTQQSSMSQTSPKSSMASTSRRQRRERRFRRYLSAGRLVRAQALLQRHPGLDVDAGQPPPLHRACARHD
APALCLLLRLGADPAHQDRHGDTALHAAARQGPDAYTDFFLPLLSRCPSAMGIKNKDGETPGQILGWGPPWDSAEEEEEDDASKEREWRQ
KLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEEL
RESRARRAQEALGDREPKPTRAGPREEHPRGAGRGSLWRFGDVPWPCPGGGDPEAMAAALVARGPPLEEQGALRRYLRVQQVRWHPDRFL

--------------------------------------------------------------
>In-frame_ENST00000474275_ENST00000376145_TCGA-NA-A4QX-01A_PHC3_chr3_169889161_-_NFKBIL1_chr6_31515940_length(transcript)=1692nt_BP=430nt
TGGAGGAGAGAAGATGGCGGAAGCGGAGTGAGTGACTAGATGATTTAAGGACCATAGTACAGCTATGGATACTGAACCAAACCCGGGAAC
ATCTTCTGTGTCAACAACAACCAGCAGTACCACCACCACCACCATCACCACTTCCTCCTCTCGAATGCAGCAGCCACAGATCTCTGTCTA
CAGTGGTTCAGACCGACATGCTGTACAGGCATTGCATCGGCCCCCCAGCTCAGCTGCTCAGTACCTTCAGCAAATGTATGCAGCCCAACA
ACAGCACTTGATGCTGCATACTGCAGCTCTTCAGCAGCAGCATTTAAGCAGCTCCCAGCTTCAGAGCCTTGCTGCTGTTCAGGCAAGTTT
GTCCAGTGGAAGACCATCTACATCTCCCACAGGAAGTGTCACACAGCAGTCAAGTATGTCCCAAACGTCTCCCAAGAGTTCCATGGCCTC
CACTTCCCGCCGCCAACGCCGAGAACGTCGCTTTCGTCGTTACTTGTCTGCAGGACGGCTGGTCCGGGCCCAGGCCCTCCTCCAGCGACA
CCCAGGCCTCGATGTAGATGCTGGGCAGCCCCCACCACTGCACCGGGCCTGTGCCCGCCACGATGCCCCTGCCCTGTGCCTGCTGCTTCG
GCTCGGGGCTGACCCTGCCCACCAGGACCGCCATGGGGACACGGCACTGCATGCTGCTGCCCGCCAGGGCCCAGATGCCTACACCGATTT
CTTCCTCCCGCTGCTAAGCCGCTGTCCCTCCGCCATGGGAATAAAGAATAAGGATGGGGAGACCCCTGGCCAAATTTTGGGCTGGGGACC
CCCCTGGGATTCTGCTGAAGAGGAGGAAGAAGATGATGCCTCCAAGGAGCGGGAATGGAGACAGAAGCTCCAGGGTGATGCCTCCCATGA
AACCCAGGAACCTGAGTCCTTCTCAGCCTGGTCAGATCGCCTGGCCCGGGAACATGCCCAGAAGTGCCAGCAGCAGCAGCGAGAAGCAGA
GGGATCCCGTCGACCCCCACGTGCTGAGGGCTCCAGCCAGAGCTGGCGACAGCAGGAGGAGGAGCAGCGGCTCTTCAGGGAGCGAGCCCG
GGCCAAGGAGGAAGAGCTGCGTGAGAGCCGAGCCAGGAGGGCGCAGGAGGCTCTAGGGGACCGAGAACCCAAGCCAACCAGGGCCGGGCC
CAGGGAAGAGCACCCCAGAGGAGCGGGGAGGGGCAGCCTCTGGCGATTTGGTGATGTGCCCTGGCCCTGCCCTGGGGGAGGGGACCCAGA
GGCCATGGCTGCAGCCCTGGTGGCCAGGGGCCCCCCTTTGGAGGAACAGGGGGCTCTGAGGAGGTACTTGAGGGTCCAGCAGGTCCGCTG
GCACCCTGACCGCTTCCTGCAGCGATTCCGAAGCCAGATTGAGACCTGGGAGCTGGGCCGTGTGATGGGAGCAGTGACAGCCCTTTCTCA
GGCCCTGAATCGCCATGCAGAGGCCCTCAAGTGACCCTAGGGAAGAAGCAAGAAACTTCGGGGCTGCAGCCTCAGGATGAGGCAGAAGGA
AGGGTAAGGGAAAGGATGGGGACCACAAGGAAGAGCCAGGTGCTGCTCAGCAGAGGATATGGGTGGGAGCGAAAGTTGTAACAAGTGGGG

>In-frame_ENST00000474275_ENST00000376145_TCGA-NA-A4QX-01A_PHC3_chr3_169889161_-_NFKBIL1_chr6_31515940_length(amino acids)=469AA_start in transcript=64_stop in transcript=1473
MDTEPNPGTSSVSTTTSSTTTTTITTSSSRMQQPQISVYSGSDRHAVQALHRPPSSAAQYLQQMYAAQQQHLMLHTAALQQQHLSSSQLQ
SLAAVQASLSSGRPSTSPTGSVTQQSSMSQTSPKSSMASTSRRQRRERRFRRYLSAGRLVRAQALLQRHPGLDVDAGQPPPLHRACARHD
APALCLLLRLGADPAHQDRHGDTALHAAARQGPDAYTDFFLPLLSRCPSAMGIKNKDGETPGQILGWGPPWDSAEEEEEDDASKEREWRQ
KLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGDR
EPKPTRAGPREEHPRGAGRGSLWRFGDVPWPCPGGGDPEAMAAALVARGPPLEEQGALRRYLRVQQVRWHPDRFLQRFRSQIETWELGRV

--------------------------------------------------------------

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Fusion Gene PPI Analysis for PHC3-NFKBIL1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for PHC3-NFKBIL1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for PHC3-NFKBIL1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource