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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ARHGEF7-TEX29 (FusionGDB2 ID:6459)

Fusion Gene Summary for ARHGEF7-TEX29

check button Fusion gene summary
Fusion gene informationFusion gene name: ARHGEF7-TEX29
Fusion gene ID: 6459
HgeneTgene
Gene symbol

ARHGEF7

TEX29

Gene ID

8874

121793

Gene nameRho guanine nucleotide exchange factor 7testis expressed 29
SynonymsBETA-PIX|COOL-1|COOL1|Nbla10314|P50|P50BP|P85|P85COOL1|P85SPR|PAK3|PIXBC13orf16|bA474D23.1
Cytomap

13q34

13q34

Type of geneprotein-codingprotein-coding
Descriptionrho guanine nucleotide exchange factor 7PAK-interacting exchange factor betaRho guanine nucleotide exchange factor (GEF) 7SH3 domain-containing proline-rich proteintestis-expressed protein 29testis-expressed sequence 29 protein
Modification date2020032720200313
UniProtAcc

Q14155

.
Ensembl transtripts involved in fusion geneENST00000317133, ENST00000375741, 
ENST00000375739, ENST00000370623, 
ENST00000544132, ENST00000218789, 
ENST00000375736, ENST00000426073, 
ENST00000375737, ENST00000375723, 
ENST00000478679, ENST00000483189, 
ENST00000283547, 
Fusion gene scores* DoF score25 X 17 X 12=51004 X 4 X 4=64
# samples 264
** MAII scorelog2(26/5100*10)=-4.29391371871777
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/64*10)=-0.678071905112638
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ARHGEF7 [Title/Abstract] AND TEX29 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointARHGEF7(111870227)-TEX29(111980530), # samples:1
ARHGEF7(111870227)-TEX29(111992210), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneARHGEF7

GO:0043547

positive regulation of GTPase activity

21048939


check buttonFusion gene breakpoints across ARHGEF7 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across TEX29 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4UCECTCGA-A5-A0G5-01AARHGEF7chr13

111870227

+TEX29chr13

111980530

+
ChimerDB4UCECTCGA-A5-A0G5-01AARHGEF7chr13

111870227

+TEX29chr13

111992210

+


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Fusion Gene ORF analysis for ARHGEF7-TEX29

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000317133ENST00000283547ARHGEF7chr13

111870227

+TEX29chr13

111980530

+
In-frameENST00000375741ENST00000283547ARHGEF7chr13

111870227

+TEX29chr13

111980530

+
In-frameENST00000375739ENST00000283547ARHGEF7chr13

111870227

+TEX29chr13

111980530

+
In-frameENST00000370623ENST00000283547ARHGEF7chr13

111870227

+TEX29chr13

111980530

+
5UTR-3CDSENST00000544132ENST00000283547ARHGEF7chr13

111870227

+TEX29chr13

111980530

+
In-frameENST00000218789ENST00000283547ARHGEF7chr13

111870227

+TEX29chr13

111980530

+
In-frameENST00000375736ENST00000283547ARHGEF7chr13

111870227

+TEX29chr13

111980530

+
In-frameENST00000426073ENST00000283547ARHGEF7chr13

111870227

+TEX29chr13

111980530

+
In-frameENST00000375737ENST00000283547ARHGEF7chr13

111870227

+TEX29chr13

111980530

+
In-frameENST00000375723ENST00000283547ARHGEF7chr13

111870227

+TEX29chr13

111980530

+
intron-3CDSENST00000478679ENST00000283547ARHGEF7chr13

111870227

+TEX29chr13

111980530

+
intron-3CDSENST00000483189ENST00000283547ARHGEF7chr13

111870227

+TEX29chr13

111980530

+
In-frameENST00000317133ENST00000283547ARHGEF7chr13

111870227

+TEX29chr13

111992210

+
In-frameENST00000375741ENST00000283547ARHGEF7chr13

111870227

+TEX29chr13

111992210

+
In-frameENST00000375739ENST00000283547ARHGEF7chr13

111870227

+TEX29chr13

111992210

+
In-frameENST00000370623ENST00000283547ARHGEF7chr13

111870227

+TEX29chr13

111992210

+
5UTR-3CDSENST00000544132ENST00000283547ARHGEF7chr13

111870227

+TEX29chr13

111992210

+
In-frameENST00000218789ENST00000283547ARHGEF7chr13

111870227

+TEX29chr13

111992210

+
In-frameENST00000375736ENST00000283547ARHGEF7chr13

111870227

+TEX29chr13

111992210

+
In-frameENST00000426073ENST00000283547ARHGEF7chr13

111870227

+TEX29chr13

111992210

+
In-frameENST00000375737ENST00000283547ARHGEF7chr13

111870227

+TEX29chr13

111992210

+
In-frameENST00000375723ENST00000283547ARHGEF7chr13

111870227

+TEX29chr13

111992210

+
intron-3CDSENST00000478679ENST00000283547ARHGEF7chr13

111870227

+TEX29chr13

111992210

+
intron-3CDSENST00000483189ENST00000283547ARHGEF7chr13

111870227

+TEX29chr13

111992210

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000317133ARHGEF7chr13111870227+ENST00000283547TEX29chr13111980530+210015787101975421
ENST00000375741ARHGEF7chr13111870227+ENST00000283547TEX29chr13111980530+1505983521380442
ENST00000375739ARHGEF7chr13111870227+ENST00000283547TEX29chr13111980530+1355833521230392
ENST00000370623ARHGEF7chr13111870227+ENST00000283547TEX29chr13111980530+9764540851283
ENST00000218789ARHGEF7chr13111870227+ENST00000283547TEX29chr13111980530+1218696411093350
ENST00000375736ARHGEF7chr13111870227+ENST00000283547TEX29chr13111980530+1194672171069350
ENST00000426073ARHGEF7chr13111870227+ENST00000283547TEX29chr13111980530+1077555155952265
ENST00000375737ARHGEF7chr13111870227+ENST00000283547TEX29chr13111980530+99046814865283
ENST00000375723ARHGEF7chr13111870227+ENST00000283547TEX29chr13111980530+94041818815265
ENST00000317133ARHGEF7chr13111870227+ENST00000283547TEX29chr13111992210+198915787101864384
ENST00000375741ARHGEF7chr13111870227+ENST00000283547TEX29chr13111992210+1394983521269405
ENST00000375739ARHGEF7chr13111870227+ENST00000283547TEX29chr13111992210+1244833521119355
ENST00000370623ARHGEF7chr13111870227+ENST00000283547TEX29chr13111992210+8654540740246
ENST00000218789ARHGEF7chr13111870227+ENST00000283547TEX29chr13111992210+110769641982313
ENST00000375736ARHGEF7chr13111870227+ENST00000283547TEX29chr13111992210+108367217958313
ENST00000426073ARHGEF7chr13111870227+ENST00000283547TEX29chr13111992210+966555155841228
ENST00000375737ARHGEF7chr13111870227+ENST00000283547TEX29chr13111992210+87946814754246
ENST00000375723ARHGEF7chr13111870227+ENST00000283547TEX29chr13111992210+82941818704228

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000317133ENST00000283547ARHGEF7chr13111870227+TEX29chr13111980530+0.0031007380.99689925
ENST00000375741ENST00000283547ARHGEF7chr13111870227+TEX29chr13111980530+0.0048442050.9951558
ENST00000375739ENST00000283547ARHGEF7chr13111870227+TEX29chr13111980530+0.003577390.9964226
ENST00000370623ENST00000283547ARHGEF7chr13111870227+TEX29chr13111980530+0.0046379680.9953621
ENST00000218789ENST00000283547ARHGEF7chr13111870227+TEX29chr13111980530+0.0058647270.99413526
ENST00000375736ENST00000283547ARHGEF7chr13111870227+TEX29chr13111980530+0.0054472930.9945528
ENST00000426073ENST00000283547ARHGEF7chr13111870227+TEX29chr13111980530+0.002309470.99769056
ENST00000375737ENST00000283547ARHGEF7chr13111870227+TEX29chr13111980530+0.0027744630.9972255
ENST00000375723ENST00000283547ARHGEF7chr13111870227+TEX29chr13111980530+0.0030459670.9969541
ENST00000317133ENST00000283547ARHGEF7chr13111870227+TEX29chr13111992210+0.0031621430.99683785
ENST00000375741ENST00000283547ARHGEF7chr13111870227+TEX29chr13111992210+0.0043165610.99568343
ENST00000375739ENST00000283547ARHGEF7chr13111870227+TEX29chr13111992210+0.0037070450.9962929
ENST00000370623ENST00000283547ARHGEF7chr13111870227+TEX29chr13111992210+0.0108779460.9891221
ENST00000218789ENST00000283547ARHGEF7chr13111870227+TEX29chr13111992210+0.0081770050.991823
ENST00000375736ENST00000283547ARHGEF7chr13111870227+TEX29chr13111992210+0.0068387920.9931612
ENST00000426073ENST00000283547ARHGEF7chr13111870227+TEX29chr13111992210+0.0045955120.9954045
ENST00000375737ENST00000283547ARHGEF7chr13111870227+TEX29chr13111992210+0.004096210.9959038
ENST00000375723ENST00000283547ARHGEF7chr13111870227+TEX29chr13111992210+0.0050853130.99491465

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Fusion Genomic Features for ARHGEF7-TEX29


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ARHGEF7chr13111870227+TEX29chr13111980529+1.31E-050.9999869
ARHGEF7chr13111870227+TEX29chr13111992209+3.23E-060.9999968
ARHGEF7chr13111870227+TEX29chr13111980529+1.31E-050.9999869
ARHGEF7chr13111870227+TEX29chr13111992209+3.23E-060.9999968

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for ARHGEF7-TEX29


check button Go to

FGviewer for the breakpoints of chr13:111870227-chr13:111980530

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ARHGEF7

Q14155

.
FUNCTION: Acts as a RAC1 guanine nucleotide exchange factor (GEF) and can induce membrane ruffling. Functions in cell migration, attachment and cell spreading. Promotes targeting of RAC1 to focal adhesions (By similarity). May function as a positive regulator of apoptosis. Downstream of NMDA receptors and CaMKK-CaMK1 signaling cascade, promotes the formation of spines and synapses in hippocampal neurons. {ECO:0000250, ECO:0000269|PubMed:18184567, ECO:0000269|PubMed:18716323, ECO:0000269|PubMed:19041750}.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneARHGEF7chr13:111870227chr13:111980530ENST00000317133+5191_133223.33333333333334783.0DomainCalponin-homology (CH)
HgeneARHGEF7chr13:111870227chr13:111980530ENST00000370623+3191_133151.33333333333334732.0DomainCalponin-homology (CH)
HgeneARHGEF7chr13:111870227chr13:111980530ENST00000375739+4181_133194.33333333333334754.0DomainCalponin-homology (CH)
HgeneARHGEF7chr13:111870227chr13:111980530ENST00000375741+620184_243244.33333333333334804.0DomainSH3
HgeneARHGEF7chr13:111870227chr13:111980530ENST00000375741+6201_133244.33333333333334804.0DomainCalponin-homology (CH)
HgeneARHGEF7chr13:111870227chr13:111992210ENST00000317133+5191_133223.33333333333334783.0DomainCalponin-homology (CH)
HgeneARHGEF7chr13:111870227chr13:111992210ENST00000370623+3191_133151.33333333333334732.0DomainCalponin-homology (CH)
HgeneARHGEF7chr13:111870227chr13:111992210ENST00000375739+4181_133194.33333333333334754.0DomainCalponin-homology (CH)
HgeneARHGEF7chr13:111870227chr13:111992210ENST00000375741+620184_243244.33333333333334804.0DomainSH3
HgeneARHGEF7chr13:111870227chr13:111992210ENST00000375741+6201_133244.33333333333334804.0DomainCalponin-homology (CH)
TgeneTEX29chr13:111870227chr13:111980530ENST000002835471678_15119.333333333333332152.0Topological domainCytoplasmic
TgeneTEX29chr13:111870227chr13:111992210ENST000002835472678_15156.333333333333336152.0Topological domainCytoplasmic
TgeneTEX29chr13:111870227chr13:111980530ENST000002835471657_7719.333333333333332152.0TransmembraneHelical
TgeneTEX29chr13:111870227chr13:111992210ENST000002835472657_7756.333333333333336152.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneARHGEF7chr13:111870227chr13:111980530ENST00000317133+519184_243223.33333333333334783.0DomainSH3
HgeneARHGEF7chr13:111870227chr13:111980530ENST00000317133+519271_451223.33333333333334783.0DomainDH
HgeneARHGEF7chr13:111870227chr13:111980530ENST00000317133+519473_578223.33333333333334783.0DomainPH
HgeneARHGEF7chr13:111870227chr13:111980530ENST00000370623+319184_243151.33333333333334732.0DomainSH3
HgeneARHGEF7chr13:111870227chr13:111980530ENST00000370623+319271_451151.33333333333334732.0DomainDH
HgeneARHGEF7chr13:111870227chr13:111980530ENST00000370623+319473_578151.33333333333334732.0DomainPH
HgeneARHGEF7chr13:111870227chr13:111980530ENST00000375723+317184_24366.33333333333333626.0DomainSH3
HgeneARHGEF7chr13:111870227chr13:111980530ENST00000375723+3171_13366.33333333333333626.0DomainCalponin-homology (CH)
HgeneARHGEF7chr13:111870227chr13:111980530ENST00000375723+317271_45166.33333333333333626.0DomainDH
HgeneARHGEF7chr13:111870227chr13:111980530ENST00000375723+317473_57866.33333333333333626.0DomainPH
HgeneARHGEF7chr13:111870227chr13:111980530ENST00000375736+420184_24366.33333333333333647.0DomainSH3
HgeneARHGEF7chr13:111870227chr13:111980530ENST00000375736+4201_13366.33333333333333647.0DomainCalponin-homology (CH)
HgeneARHGEF7chr13:111870227chr13:111980530ENST00000375736+420271_45166.33333333333333647.0DomainDH
HgeneARHGEF7chr13:111870227chr13:111980530ENST00000375736+420473_57866.33333333333333647.0DomainPH
HgeneARHGEF7chr13:111870227chr13:111980530ENST00000375739+418184_243194.33333333333334754.0DomainSH3
HgeneARHGEF7chr13:111870227chr13:111980530ENST00000375739+418271_451194.33333333333334754.0DomainDH
HgeneARHGEF7chr13:111870227chr13:111980530ENST00000375739+418473_578194.33333333333334754.0DomainPH
HgeneARHGEF7chr13:111870227chr13:111980530ENST00000375741+620271_451244.33333333333334804.0DomainDH
HgeneARHGEF7chr13:111870227chr13:111980530ENST00000375741+620473_578244.33333333333334804.0DomainPH
HgeneARHGEF7chr13:111870227chr13:111980530ENST00000426073+420184_24366.33333333333333647.0DomainSH3
HgeneARHGEF7chr13:111870227chr13:111980530ENST00000426073+4201_13366.33333333333333647.0DomainCalponin-homology (CH)
HgeneARHGEF7chr13:111870227chr13:111980530ENST00000426073+420271_45166.33333333333333647.0DomainDH
HgeneARHGEF7chr13:111870227chr13:111980530ENST00000426073+420473_57866.33333333333333647.0DomainPH
HgeneARHGEF7chr13:111870227chr13:111992210ENST00000317133+519184_243223.33333333333334783.0DomainSH3
HgeneARHGEF7chr13:111870227chr13:111992210ENST00000317133+519271_451223.33333333333334783.0DomainDH
HgeneARHGEF7chr13:111870227chr13:111992210ENST00000317133+519473_578223.33333333333334783.0DomainPH
HgeneARHGEF7chr13:111870227chr13:111992210ENST00000370623+319184_243151.33333333333334732.0DomainSH3
HgeneARHGEF7chr13:111870227chr13:111992210ENST00000370623+319271_451151.33333333333334732.0DomainDH
HgeneARHGEF7chr13:111870227chr13:111992210ENST00000370623+319473_578151.33333333333334732.0DomainPH
HgeneARHGEF7chr13:111870227chr13:111992210ENST00000375723+317184_24366.33333333333333626.0DomainSH3
HgeneARHGEF7chr13:111870227chr13:111992210ENST00000375723+3171_13366.33333333333333626.0DomainCalponin-homology (CH)
HgeneARHGEF7chr13:111870227chr13:111992210ENST00000375723+317271_45166.33333333333333626.0DomainDH
HgeneARHGEF7chr13:111870227chr13:111992210ENST00000375723+317473_57866.33333333333333626.0DomainPH
HgeneARHGEF7chr13:111870227chr13:111992210ENST00000375736+420184_24366.33333333333333647.0DomainSH3
HgeneARHGEF7chr13:111870227chr13:111992210ENST00000375736+4201_13366.33333333333333647.0DomainCalponin-homology (CH)
HgeneARHGEF7chr13:111870227chr13:111992210ENST00000375736+420271_45166.33333333333333647.0DomainDH
HgeneARHGEF7chr13:111870227chr13:111992210ENST00000375736+420473_57866.33333333333333647.0DomainPH
HgeneARHGEF7chr13:111870227chr13:111992210ENST00000375739+418184_243194.33333333333334754.0DomainSH3
HgeneARHGEF7chr13:111870227chr13:111992210ENST00000375739+418271_451194.33333333333334754.0DomainDH
HgeneARHGEF7chr13:111870227chr13:111992210ENST00000375739+418473_578194.33333333333334754.0DomainPH
HgeneARHGEF7chr13:111870227chr13:111992210ENST00000375741+620271_451244.33333333333334804.0DomainDH
HgeneARHGEF7chr13:111870227chr13:111992210ENST00000375741+620473_578244.33333333333334804.0DomainPH
HgeneARHGEF7chr13:111870227chr13:111992210ENST00000426073+420184_24366.33333333333333647.0DomainSH3
HgeneARHGEF7chr13:111870227chr13:111992210ENST00000426073+4201_13366.33333333333333647.0DomainCalponin-homology (CH)
HgeneARHGEF7chr13:111870227chr13:111992210ENST00000426073+420271_45166.33333333333333647.0DomainDH
HgeneARHGEF7chr13:111870227chr13:111992210ENST00000426073+420473_57866.33333333333333647.0DomainPH
TgeneTEX29chr13:111870227chr13:111980530ENST00000283547161_5619.333333333333332152.0Topological domainExtracellular
TgeneTEX29chr13:111870227chr13:111992210ENST00000283547261_5656.333333333333336152.0Topological domainExtracellular


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Fusion Gene Sequence for ARHGEF7-TEX29


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000317133_ENST00000283547_TCGA-A5-A0G5-01A_ARHGEF7_chr13_111870227_+_TEX29_chr13_111980530_length(transcript)=2100nt_BP=1578nt
CCCCGAGACGCAGCCAGGCGCCCGGCCCGGCCCGGCCCGGCCCTCTGCACAGCCCCACTTCAGGCCACGCCGTTTCCTTGACCTTCCCCC
GGCAGGGTCTGAAGCGTCACCGTCCGTCTAGAGCAGAGTCGCGCAGGCCCCTGCCCTGCCGGTGAGGTCGGCGCCGCGCTCCGGAGAGTC
GGTTCCTCCCGATTCAGACCCATATGGCTTCAGATGGAACCATCATTTCTGTTCCGTCATGACCGGCTTGCAAGGTAGCAAAGCGAAACA
AACGTCTCGTTTTCAGCCTGTCCCCGCCACCTTGAAATAAAACCGGCAAAAATAAAAAGAGCATTCTGGGAAGTACTTCATCATTTCAAC
GCTCACGAATTCAAAACATAAACAAAGGCTTCCGAGTGCCCCGGCCAGGGGCGCGGGGCGCACGGCGGGCCCGGGGCAGGTAAGCGCAGG
TGCGCGCCCGCCCCCACCCCCGGCTCCCTCCCCATCCGCTCCCCGCTCCCCTTCCCCTTTCCCTTCCCCGCCCGCTCCCAGCCGCCGCCG
CCGCCCCGCGCACGGCCTGGAGCGGAGGCTGCGCAGGGCGCGGGGCGGCGCGGGCCGGGCGCGGGCCGGGCGGACGGCCGCGTCTTTCTT
CTCCTGGCGGTGATGTCATTGGGCGACGGCGGCCGAGGCCGGGGGGCGGCGGCGGGCGCCCGCAGGTTCCCGAGCCGCTCCTGAGAAGGC
GCCTGACAGCGGGCCGGGGCGCACGGAGAAGCGGGCCGGGCCGGACCTGCTGGGCCGCGCCGAGCCAATCGCCGGCGCCGGCCGCTCGAT
GGGCGAGGCGGCGGCGGCGGCGGCGGGGGCCGCGGGCCGGGCCGCCGCTCCGAGGTGAAGGCGCGCGCCCCTCCCCGCCTGCCTCCCGGG
CCGCAGCGATGAATTCCGCCGAGCAAACCGTTACGTGGCTCATCACTCTGGGGGTGCTGGAGTCGCCCAAAAAAACCATCTCGGACCCGG
AGGGCTTTCTGCAGGCGTCGCTGAAGGATGGGGTGGTCCTCTGCAGGCTGCTGGAGCGCCTGCTCCCCGGGACCATCGAGAAAGTCTACC
CCGAGCCCCGGAGCGAGAGCGAGTGCCTGAGCAACATCCGCGAGTTCCTGCGCGGCTGCGGGGCTTCCCTGCGGCTGGAGACGTTTGATG
CAAATGATTTGTATCAGGGGCAGAATTTTAACAAGGTCCTCAGTTCCTTAGTGACTCTAAATAAAGTAACAGCAGACATCGGGCTGGGGA
GTGACTCCGTGTGTGCCCGGCCCTCGTCTCACCGCATAAAGTCTTTTGACTCCCTTGGATCACAGTCTTTGCACACTCGGACTTCAAAAC
TGTTCCAGGGCCAGTATCGGAGTTTGGACATGACCGATAATAGCAACAATCAACTGGTAGTAAGAGCAAAGTTTAACTTCCAGCAGACCA
ATGAGGACGAGCTTTCCTTCTCAAAAGGAGACGTCATCCATGTCACCCGTGTGGAAGAGGGAGGCTGGTGGGAGGGCACACTCAACGGCC
GGACCGGCTGGTTCCCCAGCAACTACGTGCGCGAGGTCAAGGCCAGCGTGTGTGACGTTCCTCTGTATGACATTTGTGACTACAACGTCT
CCAGGGACCGATGCCAGGAGCTCGGGTGCTGCTTCTACGAAGGCGTCTGCTACAAGAAAGCGGTTCCCATTTACATCCACGTGTTCTCTG
CCTTGATTGTGATCATCGCTGGGGCCTTCGTCATCACCATCATCTACAGAGTCATTCAGGAGAGCAGGAAAGAAAAGGCCATCCCTGTGG
ATGTCGCGCTGCCACAGAAGTCCAGCGAAAAGGCGGAGTTGGCCTCATCCAGCAGCAAGTTAGGGCTGAAGCCTGCGAGTCCTGGGCCTC
CAAGTGCTGGGCCCTCGATGAAGAGTGACGAGGATAAGGATGATGTAACAGGGACAATAACAGAAGCCGAAGAAACTGAGGACTGACTGA
GACGCATGAAGAAGTGGAGATTGTCAGAATTATCCAAATGAAATGGTACAGCAGGTGCACTGTTAACAGTGTGATGGAATGACCACCCAA

>In-frame_ENST00000317133_ENST00000283547_TCGA-A5-A0G5-01A_ARHGEF7_chr13_111870227_+_TEX29_chr13_111980530_length(amino acids)=421AA_start in transcript=710_stop in transcript=1975
MRRRLTAGRGARRSGPGRTCWAAPSQSPAPAARWARRRRRRRGPRAGPPLRGEGARPSPPASRAAAMNSAEQTVTWLITLGVLESPKKTI
SDPEGFLQASLKDGVVLCRLLERLLPGTIEKVYPEPRSESECLSNIREFLRGCGASLRLETFDANDLYQGQNFNKVLSSLVTLNKVTADI
GLGSDSVCARPSSHRIKSFDSLGSQSLHTRTSKLFQGQYRSLDMTDNSNNQLVVRAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGT
LNGRTGWFPSNYVREVKASVCDVPLYDICDYNVSRDRCQELGCCFYEGVCYKKAVPIYIHVFSALIVIIAGAFVITIIYRVIQESRKEKA

--------------------------------------------------------------
>In-frame_ENST00000375741_ENST00000283547_TCGA-A5-A0G5-01A_ARHGEF7_chr13_111870227_+_TEX29_chr13_111980530_length(transcript)=1505nt_BP=983nt
GCGGCCGAGGCCGGGGGGCGGCGGCGGGCGCCCGCAGGTTCCCGAGCCGCTCCTGAGAAGGCGCCTGACAGCGGGCCGGGGCGCACGGAG
AAGCGGGCCGGGCCGGACCTGCTGGGCCGCGCCGAGCCAATCGCCGGCGCCGGCCGCTCGATGGGCGAGGCGGCGGCGGCGGCGGCGGGG
GCCGCGGGCCGGGCCGCCGCTCCGAGGTGAAGGCGCGCGCCCCTCCCCGCCTGCCTCCCGGGCCGCAGCGATGAATTCCGCCGAGCAAAC
CGTTACGTGGCTCATCACTCTGGGGGTGCTGGAGTCGCCCAAAAAAACCATCTCGGACCCGGAGGGCTTTCTGCAGGCGTCGCTGAAGGA
TGGGGTGGTCCTCTGCAGGCTGCTGGAGCGCCTGCTCCCCGGGACCATCGAGAAAGTCTACCCCGAGCCCCGGAGCGAGAGCGAGTGCCT
GAGCAACATCCGCGAGTTCCTGCGCGGCTGCGGGGCTTCCCTGCGGCTGGAGCTCCTGTTTCCTCCTTCCCAGCCTCCTCAGCATCTGGT
AACCACCATTCTCTTGTCTGCTTCTACGTTTGATGCAAATGATTTGTATCAGGGGCAGAATTTTAACAAGGTCCTCAGTTCCTTAGTGAC
TCTAAATAAAGTAACAGCAGACATCGGGCTGGGGAGTGACTCCGTGTGTGCCCGGCCCTCGTCTCACCGCATAAAGTCTTTTGACTCCCT
TGGATCACAGTCTTTGCACACTCGGACTTCAAAACTGTTCCAGGGCCAGTATCGGAGTTTGGACATGACCGATAATAGCAACAATCAACT
GGTAGTAAGAGCAAAGTTTAACTTCCAGCAGACCAATGAGGACGAGCTTTCCTTCTCAAAAGGAGACGTCATCCATGTCACCCGTGTGGA
AGAGGGAGGCTGGTGGGAGGGCACACTCAACGGCCGGACCGGCTGGTTCCCCAGCAACTACGTGCGCGAGGTCAAGGCCAGCGTGTGTGA
CGTTCCTCTGTATGACATTTGTGACTACAACGTCTCCAGGGACCGATGCCAGGAGCTCGGGTGCTGCTTCTACGAAGGCGTCTGCTACAA
GAAAGCGGTTCCCATTTACATCCACGTGTTCTCTGCCTTGATTGTGATCATCGCTGGGGCCTTCGTCATCACCATCATCTACAGAGTCAT
TCAGGAGAGCAGGAAAGAAAAGGCCATCCCTGTGGATGTCGCGCTGCCACAGAAGTCCAGCGAAAAGGCGGAGTTGGCCTCATCCAGCAG
CAAGTTAGGGCTGAAGCCTGCGAGTCCTGGGCCTCCAAGTGCTGGGCCCTCGATGAAGAGTGACGAGGATAAGGATGATGTAACAGGGAC
AATAACAGAAGCCGAAGAAACTGAGGACTGACTGAGACGCATGAAGAAGTGGAGATTGTCAGAATTATCCAAATGAAATGGTACAGCAGG

>In-frame_ENST00000375741_ENST00000283547_TCGA-A5-A0G5-01A_ARHGEF7_chr13_111870227_+_TEX29_chr13_111980530_length(amino acids)=442AA_start in transcript=52_stop in transcript=1380
MRRRLTAGRGARRSGPGRTCWAAPSQSPAPAARWARRRRRRRGPRAGPPLRGEGARPSPPASRAAAMNSAEQTVTWLITLGVLESPKKTI
SDPEGFLQASLKDGVVLCRLLERLLPGTIEKVYPEPRSESECLSNIREFLRGCGASLRLELLFPPSQPPQHLVTTILLSASTFDANDLYQ
GQNFNKVLSSLVTLNKVTADIGLGSDSVCARPSSHRIKSFDSLGSQSLHTRTSKLFQGQYRSLDMTDNSNNQLVVRAKFNFQQTNEDELS
FSKGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYVREVKASVCDVPLYDICDYNVSRDRCQELGCCFYEGVCYKKAVPIYIHVFSALIVII

--------------------------------------------------------------
>In-frame_ENST00000375739_ENST00000283547_TCGA-A5-A0G5-01A_ARHGEF7_chr13_111870227_+_TEX29_chr13_111980530_length(transcript)=1355nt_BP=833nt
GCGGCCGAGGCCGGGGGGCGGCGGCGGGCGCCCGCAGGTTCCCGAGCCGCTCCTGAGAAGGCGCCTGACAGCGGGCCGGGGCGCACGGAG
AAGCGGGCCGGGCCGGACCTGCTGGGCCGCGCCGAGCCAATCGCCGGCGCCGGCCGCTCGATGGGCGAGGCGGCGGCGGCGGCGGCGGGG
GCCGCGGGCCGGGCCGCCGCTCCGAGGTGAAGGCGCGCGCCCCTCCCCGCCTGCCTCCCGGGCCGCAGCGATGAATTCCGCCGAGCAAAC
CGTTACGTGGCTCATCACTCTGGGGGTGCTGGAGTCGCCCAAAAAAACCATCTCGGACCCGGAGGGCTTTCTGCAGGCGTCGCTGAAGGA
TGGGGTGGTCCTCTGCAGGCTGCTGGAGCGCCTGCTCCCCGGGACCATCGAGAAAACGTTTGATGCAAATGATTTGTATCAGGGGCAGAA
TTTTAACAAGGTCCTCAGTTCCTTAGTGACTCTAAATAAAGTAACAGCAGACATCGGGCTGGGGAGTGACTCCGTGTGTGCCCGGCCCTC
GTCTCACCGCATAAAGTCTTTTGACTCCCTTGGATCACAGTCTTTGCACACTCGGACTTCAAAACTGTTCCAGGGCCAGTATCGGAGTTT
GGACATGACCGATAATAGCAACAATCAACTGGTAGTAAGAGCAAAGTTTAACTTCCAGCAGACCAATGAGGACGAGCTTTCCTTCTCAAA
AGGAGACGTCATCCATGTCACCCGTGTGGAAGAGGGAGGCTGGTGGGAGGGCACACTCAACGGCCGGACCGGCTGGTTCCCCAGCAACTA
CGTGCGCGAGGTCAAGGCCAGCGTGTGTGACGTTCCTCTGTATGACATTTGTGACTACAACGTCTCCAGGGACCGATGCCAGGAGCTCGG
GTGCTGCTTCTACGAAGGCGTCTGCTACAAGAAAGCGGTTCCCATTTACATCCACGTGTTCTCTGCCTTGATTGTGATCATCGCTGGGGC
CTTCGTCATCACCATCATCTACAGAGTCATTCAGGAGAGCAGGAAAGAAAAGGCCATCCCTGTGGATGTCGCGCTGCCACAGAAGTCCAG
CGAAAAGGCGGAGTTGGCCTCATCCAGCAGCAAGTTAGGGCTGAAGCCTGCGAGTCCTGGGCCTCCAAGTGCTGGGCCCTCGATGAAGAG
TGACGAGGATAAGGATGATGTAACAGGGACAATAACAGAAGCCGAAGAAACTGAGGACTGACTGAGACGCATGAAGAAGTGGAGATTGTC
AGAATTATCCAAATGAAATGGTACAGCAGGTGCACTGTTAACAGTGTGATGGAATGACCACCCAAAGAGAAAAAAATAAAGGTATTTTGA

>In-frame_ENST00000375739_ENST00000283547_TCGA-A5-A0G5-01A_ARHGEF7_chr13_111870227_+_TEX29_chr13_111980530_length(amino acids)=392AA_start in transcript=52_stop in transcript=1230
MRRRLTAGRGARRSGPGRTCWAAPSQSPAPAARWARRRRRRRGPRAGPPLRGEGARPSPPASRAAAMNSAEQTVTWLITLGVLESPKKTI
SDPEGFLQASLKDGVVLCRLLERLLPGTIEKTFDANDLYQGQNFNKVLSSLVTLNKVTADIGLGSDSVCARPSSHRIKSFDSLGSQSLHT
RTSKLFQGQYRSLDMTDNSNNQLVVRAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYVREVKASVCDVPLYDIC
DYNVSRDRCQELGCCFYEGVCYKKAVPIYIHVFSALIVIIAGAFVITIIYRVIQESRKEKAIPVDVALPQKSSEKAELASSSSKLGLKPA

--------------------------------------------------------------
>In-frame_ENST00000370623_ENST00000283547_TCGA-A5-A0G5-01A_ARHGEF7_chr13_111870227_+_TEX29_chr13_111980530_length(transcript)=976nt_BP=454nt
ATGAATTCCGCCGAGCAAACCGTTACGTGGCTCATCACTCTGGGGGTGCTGGAGTCGCCCAAAAAAACCATCTCGGACCCGGAGGGCTTT
CTGCAGGCGTCGCTGAAGGATGGGGTGGTCCTCTGCAGGCTGCTGGAGCGCCTGCTCCCCGGGACCATCGAGAAAGTCTACCCCGAGCCC
CGGAGCGAGAGCGAGTGCCTGAGCAACATCCGCGAGTTCCTGCGCGGCTGCGGGGCTTCCCTGCGGCTGGAGGACATGACCGATAATAGC
AACAATCAACTGGTAGTAAGAGCAAAGTTTAACTTCCAGCAGACCAATGAGGACGAGCTTTCCTTCTCAAAAGGAGACGTCATCCATGTC
ACCCGTGTGGAAGAGGGAGGCTGGTGGGAGGGCACACTCAACGGCCGGACCGGCTGGTTCCCCAGCAACTACGTGCGCGAGGTCAAGGCC
AGCGTGTGTGACGTTCCTCTGTATGACATTTGTGACTACAACGTCTCCAGGGACCGATGCCAGGAGCTCGGGTGCTGCTTCTACGAAGGC
GTCTGCTACAAGAAAGCGGTTCCCATTTACATCCACGTGTTCTCTGCCTTGATTGTGATCATCGCTGGGGCCTTCGTCATCACCATCATC
TACAGAGTCATTCAGGAGAGCAGGAAAGAAAAGGCCATCCCTGTGGATGTCGCGCTGCCACAGAAGTCCAGCGAAAAGGCGGAGTTGGCC
TCATCCAGCAGCAAGTTAGGGCTGAAGCCTGCGAGTCCTGGGCCTCCAAGTGCTGGGCCCTCGATGAAGAGTGACGAGGATAAGGATGAT
GTAACAGGGACAATAACAGAAGCCGAAGAAACTGAGGACTGACTGAGACGCATGAAGAAGTGGAGATTGTCAGAATTATCCAAATGAAAT

>In-frame_ENST00000370623_ENST00000283547_TCGA-A5-A0G5-01A_ARHGEF7_chr13_111870227_+_TEX29_chr13_111980530_length(amino acids)=283AA_start in transcript=0_stop in transcript=851
MNSAEQTVTWLITLGVLESPKKTISDPEGFLQASLKDGVVLCRLLERLLPGTIEKVYPEPRSESECLSNIREFLRGCGASLRLEDMTDNS
NNQLVVRAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYVREVKASVCDVPLYDICDYNVSRDRCQELGCCFYEG
VCYKKAVPIYIHVFSALIVIIAGAFVITIIYRVIQESRKEKAIPVDVALPQKSSEKAELASSSSKLGLKPASPGPPSAGPSMKSDEDKDD

--------------------------------------------------------------
>In-frame_ENST00000218789_ENST00000283547_TCGA-A5-A0G5-01A_ARHGEF7_chr13_111870227_+_TEX29_chr13_111980530_length(transcript)=1218nt_BP=696nt
AAAAAAGGGTGAGGAGAAGCAGCGGCTGAGCGGGTTGGCATCTGGGGCAGCGGGCTCGCTCCAGGCCGTCGGGGGCCGCTCGCCAGCGTC
GCCCGCTGTGTTGGGAGCGCGGGCCGTGGGCGTCGCTCGGCCTTGTCCGCGGCGTCCCCGCTGCCGGCCACGGCGCTCAGCGCTTGTGCT
CTGTATTGCAGGTCTACCCCGAGCCCCGGAGCGAGAGCGAGTGCCTGAGCAACATCCGCGAGTTCCTGCGCGGCTGCGGGGCTTCCCTGC
GGCTGGAGACGTTTGATGCAAATGATTTGTATCAGGGGCAGAATTTTAACAAGGTCCTCAGTTCCTTAGTGACTCTAAATAAAGTAACAG
CAGACATCGGGCTGGGGAGTGACTCCGTGTGTGCCCGGCCCTCGTCTCACCGCATAAAGTCTTTTGACTCCCTTGGATCACAGTCTTTGC
ACACTCGGACTTCAAAACTGTTCCAGGGCCAGTATCGGAGTTTGGACATGACCGATAATAGCAACAATCAACTGGTAGTAAGAGCAAAGT
TTAACTTCCAGCAGACCAATGAGGACGAGCTTTCCTTCTCAAAAGGAGACGTCATCCATGTCACCCGTGTGGAAGAGGGAGGCTGGTGGG
AGGGCACACTCAACGGCCGGACCGGCTGGTTCCCCAGCAACTACGTGCGCGAGGTCAAGGCCAGCGTGTGTGACGTTCCTCTGTATGACA
TTTGTGACTACAACGTCTCCAGGGACCGATGCCAGGAGCTCGGGTGCTGCTTCTACGAAGGCGTCTGCTACAAGAAAGCGGTTCCCATTT
ACATCCACGTGTTCTCTGCCTTGATTGTGATCATCGCTGGGGCCTTCGTCATCACCATCATCTACAGAGTCATTCAGGAGAGCAGGAAAG
AAAAGGCCATCCCTGTGGATGTCGCGCTGCCACAGAAGTCCAGCGAAAAGGCGGAGTTGGCCTCATCCAGCAGCAAGTTAGGGCTGAAGC
CTGCGAGTCCTGGGCCTCCAAGTGCTGGGCCCTCGATGAAGAGTGACGAGGATAAGGATGATGTAACAGGGACAATAACAGAAGCCGAAG
AAACTGAGGACTGACTGAGACGCATGAAGAAGTGGAGATTGTCAGAATTATCCAAATGAAATGGTACAGCAGGTGCACTGTTAACAGTGT

>In-frame_ENST00000218789_ENST00000283547_TCGA-A5-A0G5-01A_ARHGEF7_chr13_111870227_+_TEX29_chr13_111980530_length(amino acids)=350AA_start in transcript=41_stop in transcript=1093
MGQRARSRPSGAARQRRPLCWERGPWASLGLVRGVPAAGHGAQRLCSVLQVYPEPRSESECLSNIREFLRGCGASLRLETFDANDLYQGQ
NFNKVLSSLVTLNKVTADIGLGSDSVCARPSSHRIKSFDSLGSQSLHTRTSKLFQGQYRSLDMTDNSNNQLVVRAKFNFQQTNEDELSFS
KGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYVREVKASVCDVPLYDICDYNVSRDRCQELGCCFYEGVCYKKAVPIYIHVFSALIVIIAG

--------------------------------------------------------------
>In-frame_ENST00000375736_ENST00000283547_TCGA-A5-A0G5-01A_ARHGEF7_chr13_111870227_+_TEX29_chr13_111980530_length(transcript)=1194nt_BP=672nt
GCTGAGCGGGTTGGCATCTGGGGCAGCGGGCTCGCTCCAGGCCGTCGGGGGCCGCTCGCCAGCGTCGCCCGCTGTGTTGGGAGCGCGGGC
CGTGGGCGTCGCTCGGCCTTGTCCGCGGCGTCCCCGCTGCCGGCCACGGCGCTCAGCGCTTGTGCTCTGTATTGCAGGTCTACCCCGAGC
CCCGGAGCGAGAGCGAGTGCCTGAGCAACATCCGCGAGTTCCTGCGCGGCTGCGGGGCTTCCCTGCGGCTGGAGACGTTTGATGCAAATG
ATTTGTATCAGGGGCAGAATTTTAACAAGGTCCTCAGTTCCTTAGTGACTCTAAATAAAGTAACAGCAGACATCGGGCTGGGGAGTGACT
CCGTGTGTGCCCGGCCCTCGTCTCACCGCATAAAGTCTTTTGACTCCCTTGGATCACAGTCTTTGCACACTCGGACTTCAAAACTGTTCC
AGGGCCAGTATCGGAGTTTGGACATGACCGATAATAGCAACAATCAACTGGTAGTAAGAGCAAAGTTTAACTTCCAGCAGACCAATGAGG
ACGAGCTTTCCTTCTCAAAAGGAGACGTCATCCATGTCACCCGTGTGGAAGAGGGAGGCTGGTGGGAGGGCACACTCAACGGCCGGACCG
GCTGGTTCCCCAGCAACTACGTGCGCGAGGTCAAGGCCAGCGTGTGTGACGTTCCTCTGTATGACATTTGTGACTACAACGTCTCCAGGG
ACCGATGCCAGGAGCTCGGGTGCTGCTTCTACGAAGGCGTCTGCTACAAGAAAGCGGTTCCCATTTACATCCACGTGTTCTCTGCCTTGA
TTGTGATCATCGCTGGGGCCTTCGTCATCACCATCATCTACAGAGTCATTCAGGAGAGCAGGAAAGAAAAGGCCATCCCTGTGGATGTCG
CGCTGCCACAGAAGTCCAGCGAAAAGGCGGAGTTGGCCTCATCCAGCAGCAAGTTAGGGCTGAAGCCTGCGAGTCCTGGGCCTCCAAGTG
CTGGGCCCTCGATGAAGAGTGACGAGGATAAGGATGATGTAACAGGGACAATAACAGAAGCCGAAGAAACTGAGGACTGACTGAGACGCA
TGAAGAAGTGGAGATTGTCAGAATTATCCAAATGAAATGGTACAGCAGGTGCACTGTTAACAGTGTGATGGAATGACCACCCAAAGAGAA

>In-frame_ENST00000375736_ENST00000283547_TCGA-A5-A0G5-01A_ARHGEF7_chr13_111870227_+_TEX29_chr13_111980530_length(amino acids)=350AA_start in transcript=17_stop in transcript=1069
MGQRARSRPSGAARQRRPLCWERGPWASLGLVRGVPAAGHGAQRLCSVLQVYPEPRSESECLSNIREFLRGCGASLRLETFDANDLYQGQ
NFNKVLSSLVTLNKVTADIGLGSDSVCARPSSHRIKSFDSLGSQSLHTRTSKLFQGQYRSLDMTDNSNNQLVVRAKFNFQQTNEDELSFS
KGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYVREVKASVCDVPLYDICDYNVSRDRCQELGCCFYEGVCYKKAVPIYIHVFSALIVIIAG

--------------------------------------------------------------
>In-frame_ENST00000426073_ENST00000283547_TCGA-A5-A0G5-01A_ARHGEF7_chr13_111870227_+_TEX29_chr13_111980530_length(transcript)=1077nt_BP=555nt
GATGGTGGAAAGTGAGGAGAAGCAAAAAGACGACTACTTCTTTCCCCATTTCCCGGTCTGGTCTTTTTGGGGTCTACTACGTAGAGGTGC
ATCAGCCAGCGCTACCATGGAGGCAGGAGGCATTCTTTTGCTCTCGTACGTTTGATGCAAATGATTTGTATCAGGGGCAGAATTTTAACA
AGGTCCTCAGTTCCTTAGTGACTCTAAATAAAGTAACAGCAGACATCGGGCTGGGGAGTGACTCCGTGTGTGCCCGGCCCTCGTCTCACC
GCATAAAGTCTTTTGACTCCCTTGGATCACAGTCTTTGCACACTCGGACTTCAAAACTGTTCCAGGGCCAGTATCGGAGTTTGGACATGA
CCGATAATAGCAACAATCAACTGGTAGTAAGAGCAAAGTTTAACTTCCAGCAGACCAATGAGGACGAGCTTTCCTTCTCAAAAGGAGACG
TCATCCATGTCACCCGTGTGGAAGAGGGAGGCTGGTGGGAGGGCACACTCAACGGCCGGACCGGCTGGTTCCCCAGCAACTACGTGCGCG
AGGTCAAGGCCAGCGTGTGTGACGTTCCTCTGTATGACATTTGTGACTACAACGTCTCCAGGGACCGATGCCAGGAGCTCGGGTGCTGCT
TCTACGAAGGCGTCTGCTACAAGAAAGCGGTTCCCATTTACATCCACGTGTTCTCTGCCTTGATTGTGATCATCGCTGGGGCCTTCGTCA
TCACCATCATCTACAGAGTCATTCAGGAGAGCAGGAAAGAAAAGGCCATCCCTGTGGATGTCGCGCTGCCACAGAAGTCCAGCGAAAAGG
CGGAGTTGGCCTCATCCAGCAGCAAGTTAGGGCTGAAGCCTGCGAGTCCTGGGCCTCCAAGTGCTGGGCCCTCGATGAAGAGTGACGAGG
ATAAGGATGATGTAACAGGGACAATAACAGAAGCCGAAGAAACTGAGGACTGACTGAGACGCATGAAGAAGTGGAGATTGTCAGAATTAT

>In-frame_ENST00000426073_ENST00000283547_TCGA-A5-A0G5-01A_ARHGEF7_chr13_111870227_+_TEX29_chr13_111980530_length(amino acids)=265AA_start in transcript=155_stop in transcript=952
MYQGQNFNKVLSSLVTLNKVTADIGLGSDSVCARPSSHRIKSFDSLGSQSLHTRTSKLFQGQYRSLDMTDNSNNQLVVRAKFNFQQTNED
ELSFSKGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYVREVKASVCDVPLYDICDYNVSRDRCQELGCCFYEGVCYKKAVPIYIHVFSALI

--------------------------------------------------------------
>In-frame_ENST00000375737_ENST00000283547_TCGA-A5-A0G5-01A_ARHGEF7_chr13_111870227_+_TEX29_chr13_111980530_length(transcript)=990nt_BP=468nt
CACATCCTGTTATTCTGGGTTTTGTGACTTGCTGCCTTGCCACTATGAAGACGTTTGATGCAAATGATTTGTATCAGGGGCAGAATTTTA
ACAAGGTCCTCAGTTCCTTAGTGACTCTAAATAAAGTAACAGCAGACATCGGGCTGGGGAGTGACTCCGTGTGTGCCCGGCCCTCGTCTC
ACCGCATAAAGTCTTTTGACTCCCTTGGATCACAGTCTTTGCACACTCGGACTTCAAAACTGTTCCAGGGCCAGTATCGGAGTTTGGACA
TGACCGATAATAGCAACAATCAACTGGTAGTAAGAGCAAAGTTTAACTTCCAGCAGACCAATGAGGACGAGCTTTCCTTCTCAAAAGGAG
ACGTCATCCATGTCACCCGTGTGGAAGAGGGAGGCTGGTGGGAGGGCACACTCAACGGCCGGACCGGCTGGTTCCCCAGCAACTACGTGC
GCGAGGTCAAGGCCAGCGTGTGTGACGTTCCTCTGTATGACATTTGTGACTACAACGTCTCCAGGGACCGATGCCAGGAGCTCGGGTGCT
GCTTCTACGAAGGCGTCTGCTACAAGAAAGCGGTTCCCATTTACATCCACGTGTTCTCTGCCTTGATTGTGATCATCGCTGGGGCCTTCG
TCATCACCATCATCTACAGAGTCATTCAGGAGAGCAGGAAAGAAAAGGCCATCCCTGTGGATGTCGCGCTGCCACAGAAGTCCAGCGAAA
AGGCGGAGTTGGCCTCATCCAGCAGCAAGTTAGGGCTGAAGCCTGCGAGTCCTGGGCCTCCAAGTGCTGGGCCCTCGATGAAGAGTGACG
AGGATAAGGATGATGTAACAGGGACAATAACAGAAGCCGAAGAAACTGAGGACTGACTGAGACGCATGAAGAAGTGGAGATTGTCAGAAT
TATCCAAATGAAATGGTACAGCAGGTGCACTGTTAACAGTGTGATGGAATGACCACCCAAAGAGAAAAAAATAAAGGTATTTTGAAAATT

>In-frame_ENST00000375737_ENST00000283547_TCGA-A5-A0G5-01A_ARHGEF7_chr13_111870227_+_TEX29_chr13_111980530_length(amino acids)=283AA_start in transcript=14_stop in transcript=865
MGFVTCCLATMKTFDANDLYQGQNFNKVLSSLVTLNKVTADIGLGSDSVCARPSSHRIKSFDSLGSQSLHTRTSKLFQGQYRSLDMTDNS
NNQLVVRAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYVREVKASVCDVPLYDICDYNVSRDRCQELGCCFYEG
VCYKKAVPIYIHVFSALIVIIAGAFVITIIYRVIQESRKEKAIPVDVALPQKSSEKAELASSSSKLGLKPASPGPPSAGPSMKSDEDKDD

--------------------------------------------------------------
>In-frame_ENST00000375723_ENST00000283547_TCGA-A5-A0G5-01A_ARHGEF7_chr13_111870227_+_TEX29_chr13_111980530_length(transcript)=940nt_BP=418nt
ACGTTTGATGCAAATGATTTGTATCAGGGGCAGAATTTTAACAAGGTCCTCAGTTCCTTAGTGACTCTAAATAAAGTAACAGCAGACATC
GGGCTGGGGAGTGACTCCGTGTGTGCCCGGCCCTCGTCTCACCGCATAAAGTCTTTTGACTCCCTTGGATCACAGTCTTTGCACACTCGG
ACTTCAAAACTGTTCCAGGGCCAGTATCGGAGTTTGGACATGACCGATAATAGCAACAATCAACTGGTAGTAAGAGCAAAGTTTAACTTC
CAGCAGACCAATGAGGACGAGCTTTCCTTCTCAAAAGGAGACGTCATCCATGTCACCCGTGTGGAAGAGGGAGGCTGGTGGGAGGGCACA
CTCAACGGCCGGACCGGCTGGTTCCCCAGCAACTACGTGCGCGAGGTCAAGGCCAGCGTGTGTGACGTTCCTCTGTATGACATTTGTGAC
TACAACGTCTCCAGGGACCGATGCCAGGAGCTCGGGTGCTGCTTCTACGAAGGCGTCTGCTACAAGAAAGCGGTTCCCATTTACATCCAC
GTGTTCTCTGCCTTGATTGTGATCATCGCTGGGGCCTTCGTCATCACCATCATCTACAGAGTCATTCAGGAGAGCAGGAAAGAAAAGGCC
ATCCCTGTGGATGTCGCGCTGCCACAGAAGTCCAGCGAAAAGGCGGAGTTGGCCTCATCCAGCAGCAAGTTAGGGCTGAAGCCTGCGAGT
CCTGGGCCTCCAAGTGCTGGGCCCTCGATGAAGAGTGACGAGGATAAGGATGATGTAACAGGGACAATAACAGAAGCCGAAGAAACTGAG
GACTGACTGAGACGCATGAAGAAGTGGAGATTGTCAGAATTATCCAAATGAAATGGTACAGCAGGTGCACTGTTAACAGTGTGATGGAAT

>In-frame_ENST00000375723_ENST00000283547_TCGA-A5-A0G5-01A_ARHGEF7_chr13_111870227_+_TEX29_chr13_111980530_length(amino acids)=265AA_start in transcript=18_stop in transcript=815
MYQGQNFNKVLSSLVTLNKVTADIGLGSDSVCARPSSHRIKSFDSLGSQSLHTRTSKLFQGQYRSLDMTDNSNNQLVVRAKFNFQQTNED
ELSFSKGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYVREVKASVCDVPLYDICDYNVSRDRCQELGCCFYEGVCYKKAVPIYIHVFSALI

--------------------------------------------------------------
>In-frame_ENST00000317133_ENST00000283547_TCGA-A5-A0G5-01A_ARHGEF7_chr13_111870227_+_TEX29_chr13_111992210_length(transcript)=1989nt_BP=1578nt
CCCCGAGACGCAGCCAGGCGCCCGGCCCGGCCCGGCCCGGCCCTCTGCACAGCCCCACTTCAGGCCACGCCGTTTCCTTGACCTTCCCCC
GGCAGGGTCTGAAGCGTCACCGTCCGTCTAGAGCAGAGTCGCGCAGGCCCCTGCCCTGCCGGTGAGGTCGGCGCCGCGCTCCGGAGAGTC
GGTTCCTCCCGATTCAGACCCATATGGCTTCAGATGGAACCATCATTTCTGTTCCGTCATGACCGGCTTGCAAGGTAGCAAAGCGAAACA
AACGTCTCGTTTTCAGCCTGTCCCCGCCACCTTGAAATAAAACCGGCAAAAATAAAAAGAGCATTCTGGGAAGTACTTCATCATTTCAAC
GCTCACGAATTCAAAACATAAACAAAGGCTTCCGAGTGCCCCGGCCAGGGGCGCGGGGCGCACGGCGGGCCCGGGGCAGGTAAGCGCAGG
TGCGCGCCCGCCCCCACCCCCGGCTCCCTCCCCATCCGCTCCCCGCTCCCCTTCCCCTTTCCCTTCCCCGCCCGCTCCCAGCCGCCGCCG
CCGCCCCGCGCACGGCCTGGAGCGGAGGCTGCGCAGGGCGCGGGGCGGCGCGGGCCGGGCGCGGGCCGGGCGGACGGCCGCGTCTTTCTT
CTCCTGGCGGTGATGTCATTGGGCGACGGCGGCCGAGGCCGGGGGGCGGCGGCGGGCGCCCGCAGGTTCCCGAGCCGCTCCTGAGAAGGC
GCCTGACAGCGGGCCGGGGCGCACGGAGAAGCGGGCCGGGCCGGACCTGCTGGGCCGCGCCGAGCCAATCGCCGGCGCCGGCCGCTCGAT
GGGCGAGGCGGCGGCGGCGGCGGCGGGGGCCGCGGGCCGGGCCGCCGCTCCGAGGTGAAGGCGCGCGCCCCTCCCCGCCTGCCTCCCGGG
CCGCAGCGATGAATTCCGCCGAGCAAACCGTTACGTGGCTCATCACTCTGGGGGTGCTGGAGTCGCCCAAAAAAACCATCTCGGACCCGG
AGGGCTTTCTGCAGGCGTCGCTGAAGGATGGGGTGGTCCTCTGCAGGCTGCTGGAGCGCCTGCTCCCCGGGACCATCGAGAAAGTCTACC
CCGAGCCCCGGAGCGAGAGCGAGTGCCTGAGCAACATCCGCGAGTTCCTGCGCGGCTGCGGGGCTTCCCTGCGGCTGGAGACGTTTGATG
CAAATGATTTGTATCAGGGGCAGAATTTTAACAAGGTCCTCAGTTCCTTAGTGACTCTAAATAAAGTAACAGCAGACATCGGGCTGGGGA
GTGACTCCGTGTGTGCCCGGCCCTCGTCTCACCGCATAAAGTCTTTTGACTCCCTTGGATCACAGTCTTTGCACACTCGGACTTCAAAAC
TGTTCCAGGGCCAGTATCGGAGTTTGGACATGACCGATAATAGCAACAATCAACTGGTAGTAAGAGCAAAGTTTAACTTCCAGCAGACCA
ATGAGGACGAGCTTTCCTTCTCAAAAGGAGACGTCATCCATGTCACCCGTGTGGAAGAGGGAGGCTGGTGGGAGGGCACACTCAACGGCC
GGACCGGCTGGTTCCCCAGCAACTACGTGCGCGAGGTCAAGGCCAGCGTTTACATCCACGTGTTCTCTGCCTTGATTGTGATCATCGCTG
GGGCCTTCGTCATCACCATCATCTACAGAGTCATTCAGGAGAGCAGGAAAGAAAAGGCCATCCCTGTGGATGTCGCGCTGCCACAGAAGT
CCAGCGAAAAGGCGGAGTTGGCCTCATCCAGCAGCAAGTTAGGGCTGAAGCCTGCGAGTCCTGGGCCTCCAAGTGCTGGGCCCTCGATGA
AGAGTGACGAGGATAAGGATGATGTAACAGGGACAATAACAGAAGCCGAAGAAACTGAGGACTGACTGAGACGCATGAAGAAGTGGAGAT
TGTCAGAATTATCCAAATGAAATGGTACAGCAGGTGCACTGTTAACAGTGTGATGGAATGACCACCCAAAGAGAAAAAAATAAAGGTATT

>In-frame_ENST00000317133_ENST00000283547_TCGA-A5-A0G5-01A_ARHGEF7_chr13_111870227_+_TEX29_chr13_111992210_length(amino acids)=384AA_start in transcript=710_stop in transcript=1864
MRRRLTAGRGARRSGPGRTCWAAPSQSPAPAARWARRRRRRRGPRAGPPLRGEGARPSPPASRAAAMNSAEQTVTWLITLGVLESPKKTI
SDPEGFLQASLKDGVVLCRLLERLLPGTIEKVYPEPRSESECLSNIREFLRGCGASLRLETFDANDLYQGQNFNKVLSSLVTLNKVTADI
GLGSDSVCARPSSHRIKSFDSLGSQSLHTRTSKLFQGQYRSLDMTDNSNNQLVVRAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGT
LNGRTGWFPSNYVREVKASVYIHVFSALIVIIAGAFVITIIYRVIQESRKEKAIPVDVALPQKSSEKAELASSSSKLGLKPASPGPPSAG

--------------------------------------------------------------
>In-frame_ENST00000375741_ENST00000283547_TCGA-A5-A0G5-01A_ARHGEF7_chr13_111870227_+_TEX29_chr13_111992210_length(transcript)=1394nt_BP=983nt
GCGGCCGAGGCCGGGGGGCGGCGGCGGGCGCCCGCAGGTTCCCGAGCCGCTCCTGAGAAGGCGCCTGACAGCGGGCCGGGGCGCACGGAG
AAGCGGGCCGGGCCGGACCTGCTGGGCCGCGCCGAGCCAATCGCCGGCGCCGGCCGCTCGATGGGCGAGGCGGCGGCGGCGGCGGCGGGG
GCCGCGGGCCGGGCCGCCGCTCCGAGGTGAAGGCGCGCGCCCCTCCCCGCCTGCCTCCCGGGCCGCAGCGATGAATTCCGCCGAGCAAAC
CGTTACGTGGCTCATCACTCTGGGGGTGCTGGAGTCGCCCAAAAAAACCATCTCGGACCCGGAGGGCTTTCTGCAGGCGTCGCTGAAGGA
TGGGGTGGTCCTCTGCAGGCTGCTGGAGCGCCTGCTCCCCGGGACCATCGAGAAAGTCTACCCCGAGCCCCGGAGCGAGAGCGAGTGCCT
GAGCAACATCCGCGAGTTCCTGCGCGGCTGCGGGGCTTCCCTGCGGCTGGAGCTCCTGTTTCCTCCTTCCCAGCCTCCTCAGCATCTGGT
AACCACCATTCTCTTGTCTGCTTCTACGTTTGATGCAAATGATTTGTATCAGGGGCAGAATTTTAACAAGGTCCTCAGTTCCTTAGTGAC
TCTAAATAAAGTAACAGCAGACATCGGGCTGGGGAGTGACTCCGTGTGTGCCCGGCCCTCGTCTCACCGCATAAAGTCTTTTGACTCCCT
TGGATCACAGTCTTTGCACACTCGGACTTCAAAACTGTTCCAGGGCCAGTATCGGAGTTTGGACATGACCGATAATAGCAACAATCAACT
GGTAGTAAGAGCAAAGTTTAACTTCCAGCAGACCAATGAGGACGAGCTTTCCTTCTCAAAAGGAGACGTCATCCATGTCACCCGTGTGGA
AGAGGGAGGCTGGTGGGAGGGCACACTCAACGGCCGGACCGGCTGGTTCCCCAGCAACTACGTGCGCGAGGTCAAGGCCAGCGTTTACAT
CCACGTGTTCTCTGCCTTGATTGTGATCATCGCTGGGGCCTTCGTCATCACCATCATCTACAGAGTCATTCAGGAGAGCAGGAAAGAAAA
GGCCATCCCTGTGGATGTCGCGCTGCCACAGAAGTCCAGCGAAAAGGCGGAGTTGGCCTCATCCAGCAGCAAGTTAGGGCTGAAGCCTGC
GAGTCCTGGGCCTCCAAGTGCTGGGCCCTCGATGAAGAGTGACGAGGATAAGGATGATGTAACAGGGACAATAACAGAAGCCGAAGAAAC
TGAGGACTGACTGAGACGCATGAAGAAGTGGAGATTGTCAGAATTATCCAAATGAAATGGTACAGCAGGTGCACTGTTAACAGTGTGATG

>In-frame_ENST00000375741_ENST00000283547_TCGA-A5-A0G5-01A_ARHGEF7_chr13_111870227_+_TEX29_chr13_111992210_length(amino acids)=405AA_start in transcript=52_stop in transcript=1269
MRRRLTAGRGARRSGPGRTCWAAPSQSPAPAARWARRRRRRRGPRAGPPLRGEGARPSPPASRAAAMNSAEQTVTWLITLGVLESPKKTI
SDPEGFLQASLKDGVVLCRLLERLLPGTIEKVYPEPRSESECLSNIREFLRGCGASLRLELLFPPSQPPQHLVTTILLSASTFDANDLYQ
GQNFNKVLSSLVTLNKVTADIGLGSDSVCARPSSHRIKSFDSLGSQSLHTRTSKLFQGQYRSLDMTDNSNNQLVVRAKFNFQQTNEDELS
FSKGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYVREVKASVYIHVFSALIVIIAGAFVITIIYRVIQESRKEKAIPVDVALPQKSSEKAE

--------------------------------------------------------------
>In-frame_ENST00000375739_ENST00000283547_TCGA-A5-A0G5-01A_ARHGEF7_chr13_111870227_+_TEX29_chr13_111992210_length(transcript)=1244nt_BP=833nt
GCGGCCGAGGCCGGGGGGCGGCGGCGGGCGCCCGCAGGTTCCCGAGCCGCTCCTGAGAAGGCGCCTGACAGCGGGCCGGGGCGCACGGAG
AAGCGGGCCGGGCCGGACCTGCTGGGCCGCGCCGAGCCAATCGCCGGCGCCGGCCGCTCGATGGGCGAGGCGGCGGCGGCGGCGGCGGGG
GCCGCGGGCCGGGCCGCCGCTCCGAGGTGAAGGCGCGCGCCCCTCCCCGCCTGCCTCCCGGGCCGCAGCGATGAATTCCGCCGAGCAAAC
CGTTACGTGGCTCATCACTCTGGGGGTGCTGGAGTCGCCCAAAAAAACCATCTCGGACCCGGAGGGCTTTCTGCAGGCGTCGCTGAAGGA
TGGGGTGGTCCTCTGCAGGCTGCTGGAGCGCCTGCTCCCCGGGACCATCGAGAAAACGTTTGATGCAAATGATTTGTATCAGGGGCAGAA
TTTTAACAAGGTCCTCAGTTCCTTAGTGACTCTAAATAAAGTAACAGCAGACATCGGGCTGGGGAGTGACTCCGTGTGTGCCCGGCCCTC
GTCTCACCGCATAAAGTCTTTTGACTCCCTTGGATCACAGTCTTTGCACACTCGGACTTCAAAACTGTTCCAGGGCCAGTATCGGAGTTT
GGACATGACCGATAATAGCAACAATCAACTGGTAGTAAGAGCAAAGTTTAACTTCCAGCAGACCAATGAGGACGAGCTTTCCTTCTCAAA
AGGAGACGTCATCCATGTCACCCGTGTGGAAGAGGGAGGCTGGTGGGAGGGCACACTCAACGGCCGGACCGGCTGGTTCCCCAGCAACTA
CGTGCGCGAGGTCAAGGCCAGCGTTTACATCCACGTGTTCTCTGCCTTGATTGTGATCATCGCTGGGGCCTTCGTCATCACCATCATCTA
CAGAGTCATTCAGGAGAGCAGGAAAGAAAAGGCCATCCCTGTGGATGTCGCGCTGCCACAGAAGTCCAGCGAAAAGGCGGAGTTGGCCTC
ATCCAGCAGCAAGTTAGGGCTGAAGCCTGCGAGTCCTGGGCCTCCAAGTGCTGGGCCCTCGATGAAGAGTGACGAGGATAAGGATGATGT
AACAGGGACAATAACAGAAGCCGAAGAAACTGAGGACTGACTGAGACGCATGAAGAAGTGGAGATTGTCAGAATTATCCAAATGAAATGG

>In-frame_ENST00000375739_ENST00000283547_TCGA-A5-A0G5-01A_ARHGEF7_chr13_111870227_+_TEX29_chr13_111992210_length(amino acids)=355AA_start in transcript=52_stop in transcript=1119
MRRRLTAGRGARRSGPGRTCWAAPSQSPAPAARWARRRRRRRGPRAGPPLRGEGARPSPPASRAAAMNSAEQTVTWLITLGVLESPKKTI
SDPEGFLQASLKDGVVLCRLLERLLPGTIEKTFDANDLYQGQNFNKVLSSLVTLNKVTADIGLGSDSVCARPSSHRIKSFDSLGSQSLHT
RTSKLFQGQYRSLDMTDNSNNQLVVRAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYVREVKASVYIHVFSALI

--------------------------------------------------------------
>In-frame_ENST00000370623_ENST00000283547_TCGA-A5-A0G5-01A_ARHGEF7_chr13_111870227_+_TEX29_chr13_111992210_length(transcript)=865nt_BP=454nt
ATGAATTCCGCCGAGCAAACCGTTACGTGGCTCATCACTCTGGGGGTGCTGGAGTCGCCCAAAAAAACCATCTCGGACCCGGAGGGCTTT
CTGCAGGCGTCGCTGAAGGATGGGGTGGTCCTCTGCAGGCTGCTGGAGCGCCTGCTCCCCGGGACCATCGAGAAAGTCTACCCCGAGCCC
CGGAGCGAGAGCGAGTGCCTGAGCAACATCCGCGAGTTCCTGCGCGGCTGCGGGGCTTCCCTGCGGCTGGAGGACATGACCGATAATAGC
AACAATCAACTGGTAGTAAGAGCAAAGTTTAACTTCCAGCAGACCAATGAGGACGAGCTTTCCTTCTCAAAAGGAGACGTCATCCATGTC
ACCCGTGTGGAAGAGGGAGGCTGGTGGGAGGGCACACTCAACGGCCGGACCGGCTGGTTCCCCAGCAACTACGTGCGCGAGGTCAAGGCC
AGCGTTTACATCCACGTGTTCTCTGCCTTGATTGTGATCATCGCTGGGGCCTTCGTCATCACCATCATCTACAGAGTCATTCAGGAGAGC
AGGAAAGAAAAGGCCATCCCTGTGGATGTCGCGCTGCCACAGAAGTCCAGCGAAAAGGCGGAGTTGGCCTCATCCAGCAGCAAGTTAGGG
CTGAAGCCTGCGAGTCCTGGGCCTCCAAGTGCTGGGCCCTCGATGAAGAGTGACGAGGATAAGGATGATGTAACAGGGACAATAACAGAA
GCCGAAGAAACTGAGGACTGACTGAGACGCATGAAGAAGTGGAGATTGTCAGAATTATCCAAATGAAATGGTACAGCAGGTGCACTGTTA

>In-frame_ENST00000370623_ENST00000283547_TCGA-A5-A0G5-01A_ARHGEF7_chr13_111870227_+_TEX29_chr13_111992210_length(amino acids)=246AA_start in transcript=0_stop in transcript=740
MNSAEQTVTWLITLGVLESPKKTISDPEGFLQASLKDGVVLCRLLERLLPGTIEKVYPEPRSESECLSNIREFLRGCGASLRLEDMTDNS
NNQLVVRAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYVREVKASVYIHVFSALIVIIAGAFVITIIYRVIQES

--------------------------------------------------------------
>In-frame_ENST00000218789_ENST00000283547_TCGA-A5-A0G5-01A_ARHGEF7_chr13_111870227_+_TEX29_chr13_111992210_length(transcript)=1107nt_BP=696nt
AAAAAAGGGTGAGGAGAAGCAGCGGCTGAGCGGGTTGGCATCTGGGGCAGCGGGCTCGCTCCAGGCCGTCGGGGGCCGCTCGCCAGCGTC
GCCCGCTGTGTTGGGAGCGCGGGCCGTGGGCGTCGCTCGGCCTTGTCCGCGGCGTCCCCGCTGCCGGCCACGGCGCTCAGCGCTTGTGCT
CTGTATTGCAGGTCTACCCCGAGCCCCGGAGCGAGAGCGAGTGCCTGAGCAACATCCGCGAGTTCCTGCGCGGCTGCGGGGCTTCCCTGC
GGCTGGAGACGTTTGATGCAAATGATTTGTATCAGGGGCAGAATTTTAACAAGGTCCTCAGTTCCTTAGTGACTCTAAATAAAGTAACAG
CAGACATCGGGCTGGGGAGTGACTCCGTGTGTGCCCGGCCCTCGTCTCACCGCATAAAGTCTTTTGACTCCCTTGGATCACAGTCTTTGC
ACACTCGGACTTCAAAACTGTTCCAGGGCCAGTATCGGAGTTTGGACATGACCGATAATAGCAACAATCAACTGGTAGTAAGAGCAAAGT
TTAACTTCCAGCAGACCAATGAGGACGAGCTTTCCTTCTCAAAAGGAGACGTCATCCATGTCACCCGTGTGGAAGAGGGAGGCTGGTGGG
AGGGCACACTCAACGGCCGGACCGGCTGGTTCCCCAGCAACTACGTGCGCGAGGTCAAGGCCAGCGTTTACATCCACGTGTTCTCTGCCT
TGATTGTGATCATCGCTGGGGCCTTCGTCATCACCATCATCTACAGAGTCATTCAGGAGAGCAGGAAAGAAAAGGCCATCCCTGTGGATG
TCGCGCTGCCACAGAAGTCCAGCGAAAAGGCGGAGTTGGCCTCATCCAGCAGCAAGTTAGGGCTGAAGCCTGCGAGTCCTGGGCCTCCAA
GTGCTGGGCCCTCGATGAAGAGTGACGAGGATAAGGATGATGTAACAGGGACAATAACAGAAGCCGAAGAAACTGAGGACTGACTGAGAC
GCATGAAGAAGTGGAGATTGTCAGAATTATCCAAATGAAATGGTACAGCAGGTGCACTGTTAACAGTGTGATGGAATGACCACCCAAAGA

>In-frame_ENST00000218789_ENST00000283547_TCGA-A5-A0G5-01A_ARHGEF7_chr13_111870227_+_TEX29_chr13_111992210_length(amino acids)=313AA_start in transcript=41_stop in transcript=982
MGQRARSRPSGAARQRRPLCWERGPWASLGLVRGVPAAGHGAQRLCSVLQVYPEPRSESECLSNIREFLRGCGASLRLETFDANDLYQGQ
NFNKVLSSLVTLNKVTADIGLGSDSVCARPSSHRIKSFDSLGSQSLHTRTSKLFQGQYRSLDMTDNSNNQLVVRAKFNFQQTNEDELSFS
KGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYVREVKASVYIHVFSALIVIIAGAFVITIIYRVIQESRKEKAIPVDVALPQKSSEKAELA

--------------------------------------------------------------
>In-frame_ENST00000375736_ENST00000283547_TCGA-A5-A0G5-01A_ARHGEF7_chr13_111870227_+_TEX29_chr13_111992210_length(transcript)=1083nt_BP=672nt
GCTGAGCGGGTTGGCATCTGGGGCAGCGGGCTCGCTCCAGGCCGTCGGGGGCCGCTCGCCAGCGTCGCCCGCTGTGTTGGGAGCGCGGGC
CGTGGGCGTCGCTCGGCCTTGTCCGCGGCGTCCCCGCTGCCGGCCACGGCGCTCAGCGCTTGTGCTCTGTATTGCAGGTCTACCCCGAGC
CCCGGAGCGAGAGCGAGTGCCTGAGCAACATCCGCGAGTTCCTGCGCGGCTGCGGGGCTTCCCTGCGGCTGGAGACGTTTGATGCAAATG
ATTTGTATCAGGGGCAGAATTTTAACAAGGTCCTCAGTTCCTTAGTGACTCTAAATAAAGTAACAGCAGACATCGGGCTGGGGAGTGACT
CCGTGTGTGCCCGGCCCTCGTCTCACCGCATAAAGTCTTTTGACTCCCTTGGATCACAGTCTTTGCACACTCGGACTTCAAAACTGTTCC
AGGGCCAGTATCGGAGTTTGGACATGACCGATAATAGCAACAATCAACTGGTAGTAAGAGCAAAGTTTAACTTCCAGCAGACCAATGAGG
ACGAGCTTTCCTTCTCAAAAGGAGACGTCATCCATGTCACCCGTGTGGAAGAGGGAGGCTGGTGGGAGGGCACACTCAACGGCCGGACCG
GCTGGTTCCCCAGCAACTACGTGCGCGAGGTCAAGGCCAGCGTTTACATCCACGTGTTCTCTGCCTTGATTGTGATCATCGCTGGGGCCT
TCGTCATCACCATCATCTACAGAGTCATTCAGGAGAGCAGGAAAGAAAAGGCCATCCCTGTGGATGTCGCGCTGCCACAGAAGTCCAGCG
AAAAGGCGGAGTTGGCCTCATCCAGCAGCAAGTTAGGGCTGAAGCCTGCGAGTCCTGGGCCTCCAAGTGCTGGGCCCTCGATGAAGAGTG
ACGAGGATAAGGATGATGTAACAGGGACAATAACAGAAGCCGAAGAAACTGAGGACTGACTGAGACGCATGAAGAAGTGGAGATTGTCAG
AATTATCCAAATGAAATGGTACAGCAGGTGCACTGTTAACAGTGTGATGGAATGACCACCCAAAGAGAAAAAAATAAAGGTATTTTGAAA

>In-frame_ENST00000375736_ENST00000283547_TCGA-A5-A0G5-01A_ARHGEF7_chr13_111870227_+_TEX29_chr13_111992210_length(amino acids)=313AA_start in transcript=17_stop in transcript=958
MGQRARSRPSGAARQRRPLCWERGPWASLGLVRGVPAAGHGAQRLCSVLQVYPEPRSESECLSNIREFLRGCGASLRLETFDANDLYQGQ
NFNKVLSSLVTLNKVTADIGLGSDSVCARPSSHRIKSFDSLGSQSLHTRTSKLFQGQYRSLDMTDNSNNQLVVRAKFNFQQTNEDELSFS
KGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYVREVKASVYIHVFSALIVIIAGAFVITIIYRVIQESRKEKAIPVDVALPQKSSEKAELA

--------------------------------------------------------------
>In-frame_ENST00000426073_ENST00000283547_TCGA-A5-A0G5-01A_ARHGEF7_chr13_111870227_+_TEX29_chr13_111992210_length(transcript)=966nt_BP=555nt
GATGGTGGAAAGTGAGGAGAAGCAAAAAGACGACTACTTCTTTCCCCATTTCCCGGTCTGGTCTTTTTGGGGTCTACTACGTAGAGGTGC
ATCAGCCAGCGCTACCATGGAGGCAGGAGGCATTCTTTTGCTCTCGTACGTTTGATGCAAATGATTTGTATCAGGGGCAGAATTTTAACA
AGGTCCTCAGTTCCTTAGTGACTCTAAATAAAGTAACAGCAGACATCGGGCTGGGGAGTGACTCCGTGTGTGCCCGGCCCTCGTCTCACC
GCATAAAGTCTTTTGACTCCCTTGGATCACAGTCTTTGCACACTCGGACTTCAAAACTGTTCCAGGGCCAGTATCGGAGTTTGGACATGA
CCGATAATAGCAACAATCAACTGGTAGTAAGAGCAAAGTTTAACTTCCAGCAGACCAATGAGGACGAGCTTTCCTTCTCAAAAGGAGACG
TCATCCATGTCACCCGTGTGGAAGAGGGAGGCTGGTGGGAGGGCACACTCAACGGCCGGACCGGCTGGTTCCCCAGCAACTACGTGCGCG
AGGTCAAGGCCAGCGTTTACATCCACGTGTTCTCTGCCTTGATTGTGATCATCGCTGGGGCCTTCGTCATCACCATCATCTACAGAGTCA
TTCAGGAGAGCAGGAAAGAAAAGGCCATCCCTGTGGATGTCGCGCTGCCACAGAAGTCCAGCGAAAAGGCGGAGTTGGCCTCATCCAGCA
GCAAGTTAGGGCTGAAGCCTGCGAGTCCTGGGCCTCCAAGTGCTGGGCCCTCGATGAAGAGTGACGAGGATAAGGATGATGTAACAGGGA
CAATAACAGAAGCCGAAGAAACTGAGGACTGACTGAGACGCATGAAGAAGTGGAGATTGTCAGAATTATCCAAATGAAATGGTACAGCAG

>In-frame_ENST00000426073_ENST00000283547_TCGA-A5-A0G5-01A_ARHGEF7_chr13_111870227_+_TEX29_chr13_111992210_length(amino acids)=228AA_start in transcript=155_stop in transcript=841
MYQGQNFNKVLSSLVTLNKVTADIGLGSDSVCARPSSHRIKSFDSLGSQSLHTRTSKLFQGQYRSLDMTDNSNNQLVVRAKFNFQQTNED
ELSFSKGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYVREVKASVYIHVFSALIVIIAGAFVITIIYRVIQESRKEKAIPVDVALPQKSSE

--------------------------------------------------------------
>In-frame_ENST00000375737_ENST00000283547_TCGA-A5-A0G5-01A_ARHGEF7_chr13_111870227_+_TEX29_chr13_111992210_length(transcript)=879nt_BP=468nt
CACATCCTGTTATTCTGGGTTTTGTGACTTGCTGCCTTGCCACTATGAAGACGTTTGATGCAAATGATTTGTATCAGGGGCAGAATTTTA
ACAAGGTCCTCAGTTCCTTAGTGACTCTAAATAAAGTAACAGCAGACATCGGGCTGGGGAGTGACTCCGTGTGTGCCCGGCCCTCGTCTC
ACCGCATAAAGTCTTTTGACTCCCTTGGATCACAGTCTTTGCACACTCGGACTTCAAAACTGTTCCAGGGCCAGTATCGGAGTTTGGACA
TGACCGATAATAGCAACAATCAACTGGTAGTAAGAGCAAAGTTTAACTTCCAGCAGACCAATGAGGACGAGCTTTCCTTCTCAAAAGGAG
ACGTCATCCATGTCACCCGTGTGGAAGAGGGAGGCTGGTGGGAGGGCACACTCAACGGCCGGACCGGCTGGTTCCCCAGCAACTACGTGC
GCGAGGTCAAGGCCAGCGTTTACATCCACGTGTTCTCTGCCTTGATTGTGATCATCGCTGGGGCCTTCGTCATCACCATCATCTACAGAG
TCATTCAGGAGAGCAGGAAAGAAAAGGCCATCCCTGTGGATGTCGCGCTGCCACAGAAGTCCAGCGAAAAGGCGGAGTTGGCCTCATCCA
GCAGCAAGTTAGGGCTGAAGCCTGCGAGTCCTGGGCCTCCAAGTGCTGGGCCCTCGATGAAGAGTGACGAGGATAAGGATGATGTAACAG
GGACAATAACAGAAGCCGAAGAAACTGAGGACTGACTGAGACGCATGAAGAAGTGGAGATTGTCAGAATTATCCAAATGAAATGGTACAG

>In-frame_ENST00000375737_ENST00000283547_TCGA-A5-A0G5-01A_ARHGEF7_chr13_111870227_+_TEX29_chr13_111992210_length(amino acids)=246AA_start in transcript=14_stop in transcript=754
MGFVTCCLATMKTFDANDLYQGQNFNKVLSSLVTLNKVTADIGLGSDSVCARPSSHRIKSFDSLGSQSLHTRTSKLFQGQYRSLDMTDNS
NNQLVVRAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYVREVKASVYIHVFSALIVIIAGAFVITIIYRVIQES

--------------------------------------------------------------
>In-frame_ENST00000375723_ENST00000283547_TCGA-A5-A0G5-01A_ARHGEF7_chr13_111870227_+_TEX29_chr13_111992210_length(transcript)=829nt_BP=418nt
ACGTTTGATGCAAATGATTTGTATCAGGGGCAGAATTTTAACAAGGTCCTCAGTTCCTTAGTGACTCTAAATAAAGTAACAGCAGACATC
GGGCTGGGGAGTGACTCCGTGTGTGCCCGGCCCTCGTCTCACCGCATAAAGTCTTTTGACTCCCTTGGATCACAGTCTTTGCACACTCGG
ACTTCAAAACTGTTCCAGGGCCAGTATCGGAGTTTGGACATGACCGATAATAGCAACAATCAACTGGTAGTAAGAGCAAAGTTTAACTTC
CAGCAGACCAATGAGGACGAGCTTTCCTTCTCAAAAGGAGACGTCATCCATGTCACCCGTGTGGAAGAGGGAGGCTGGTGGGAGGGCACA
CTCAACGGCCGGACCGGCTGGTTCCCCAGCAACTACGTGCGCGAGGTCAAGGCCAGCGTTTACATCCACGTGTTCTCTGCCTTGATTGTG
ATCATCGCTGGGGCCTTCGTCATCACCATCATCTACAGAGTCATTCAGGAGAGCAGGAAAGAAAAGGCCATCCCTGTGGATGTCGCGCTG
CCACAGAAGTCCAGCGAAAAGGCGGAGTTGGCCTCATCCAGCAGCAAGTTAGGGCTGAAGCCTGCGAGTCCTGGGCCTCCAAGTGCTGGG
CCCTCGATGAAGAGTGACGAGGATAAGGATGATGTAACAGGGACAATAACAGAAGCCGAAGAAACTGAGGACTGACTGAGACGCATGAAG
AAGTGGAGATTGTCAGAATTATCCAAATGAAATGGTACAGCAGGTGCACTGTTAACAGTGTGATGGAATGACCACCCAAAGAGAAAAAAA

>In-frame_ENST00000375723_ENST00000283547_TCGA-A5-A0G5-01A_ARHGEF7_chr13_111870227_+_TEX29_chr13_111992210_length(amino acids)=228AA_start in transcript=18_stop in transcript=704
MYQGQNFNKVLSSLVTLNKVTADIGLGSDSVCARPSSHRIKSFDSLGSQSLHTRTSKLFQGQYRSLDMTDNSNNQLVVRAKFNFQQTNED
ELSFSKGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYVREVKASVYIHVFSALIVIIAGAFVITIIYRVIQESRKEKAIPVDVALPQKSSE

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ARHGEF7-TEX29


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ARHGEF7-TEX29


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ARHGEF7-TEX29


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource