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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:PIGK-TGFBR3 (FusionGDB2 ID:64831)

Fusion Gene Summary for PIGK-TGFBR3

check button Fusion gene summary
Fusion gene informationFusion gene name: PIGK-TGFBR3
Fusion gene ID: 64831
HgeneTgene
Gene symbol

PIGK

TGFBR3

Gene ID

10026

7049

Gene namephosphatidylinositol glycan anchor biosynthesis class Ktransforming growth factor beta receptor 3
SynonymsGPI8BGCAN|betaglycan
Cytomap

1p31.1

1p22.1

Type of geneprotein-codingprotein-coding
DescriptionGPI-anchor transamidaseGPI transamidase subunitGPI8 homologPIG-Kphosphatidylinositol glycan, class Kphosphatidylinositol-glycan biosynthesis class K proteintransforming growth factor beta receptor type 3TGF-beta receptor type 3TGF-beta receptor type IIITGFR-3betaglycan proteoglycantransforming growth factor beta receptor III
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000370812, ENST00000445065, 
ENST00000370813, ENST00000359130, 
ENST00000478391, 		ENST00000212355, 
ENST00000370399, ENST00000525962, 
ENST00000468996, 
Fusion gene scores* DoF score7 X 6 X 6=25210 X 9 X 9=810
# samples 710
** MAII scorelog2(7/252*10)=-1.84799690655495
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(10/810*10)=-3.01792190799726
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: PIGK [Title/Abstract] AND TGFBR3 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointPIGK(77587960)-TGFBR3(92187701), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneTGFBR3

GO:0001837

epithelial to mesenchymal transition

18184661

TgeneTGFBR3

GO:0007179

transforming growth factor beta receptor signaling pathway

12958365

TgeneTGFBR3

GO:0030509

BMP signaling pathway

18184661

TgeneTGFBR3

GO:0032354

response to follicle-stimulating hormone

14557487

TgeneTGFBR3

GO:0034695

response to prostaglandin E

14557487

TgeneTGFBR3

GO:0034699

response to luteinizing hormone

14557487

TgeneTGFBR3

GO:0051271

negative regulation of cellular component movement

17999987

TgeneTGFBR3

GO:0060317

cardiac epithelial to mesenchymal transition

18184661


check buttonFusion gene breakpoints across PIGK (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across TGFBR3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUSCTCGA-85-8582-01APIGKchr1

77587960

-TGFBR3chr1

92187701

-
ChimerDB4LUSCTCGA-85-8582PIGKchr1

77587960

-TGFBR3chr1

92187701

-
ChimerDB4LUSCTCGA-85-8582-01APIGKchr1

77587960

-TGFBR3chr1

92187701

-


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Fusion Gene ORF analysis for PIGK-TGFBR3

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000370812ENST00000212355PIGKchr1

77587960

-TGFBR3chr1

92187701

-
In-frameENST00000370812ENST00000370399PIGKchr1

77587960

-TGFBR3chr1

92187701

-
In-frameENST00000370812ENST00000525962PIGKchr1

77587960

-TGFBR3chr1

92187701

-
5CDS-intronENST00000370812ENST00000468996PIGKchr1

77587960

-TGFBR3chr1

92187701

-
In-frameENST00000445065ENST00000212355PIGKchr1

77587960

-TGFBR3chr1

92187701

-
In-frameENST00000445065ENST00000370399PIGKchr1

77587960

-TGFBR3chr1

92187701

-
In-frameENST00000445065ENST00000525962PIGKchr1

77587960

-TGFBR3chr1

92187701

-
5CDS-intronENST00000445065ENST00000468996PIGKchr1

77587960

-TGFBR3chr1

92187701

-
In-frameENST00000370813ENST00000212355PIGKchr1

77587960

-TGFBR3chr1

92187701

-
In-frameENST00000370813ENST00000370399PIGKchr1

77587960

-TGFBR3chr1

92187701

-
In-frameENST00000370813ENST00000525962PIGKchr1

77587960

-TGFBR3chr1

92187701

-
5CDS-intronENST00000370813ENST00000468996PIGKchr1

77587960

-TGFBR3chr1

92187701

-
intron-3CDSENST00000359130ENST00000212355PIGKchr1

77587960

-TGFBR3chr1

92187701

-
intron-3CDSENST00000359130ENST00000370399PIGKchr1

77587960

-TGFBR3chr1

92187701

-
intron-3CDSENST00000359130ENST00000525962PIGKchr1

77587960

-TGFBR3chr1

92187701

-
intron-intronENST00000359130ENST00000468996PIGKchr1

77587960

-TGFBR3chr1

92187701

-
intron-3CDSENST00000478391ENST00000212355PIGKchr1

77587960

-TGFBR3chr1

92187701

-
intron-3CDSENST00000478391ENST00000370399PIGKchr1

77587960

-TGFBR3chr1

92187701

-
intron-3CDSENST00000478391ENST00000525962PIGKchr1

77587960

-TGFBR3chr1

92187701

-
intron-intronENST00000478391ENST00000468996PIGKchr1

77587960

-TGFBR3chr1

92187701

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000370812PIGKchr177587960-ENST00000212355TGFBR3chr192187701-6160109592765918
ENST00000370812PIGKchr177587960-ENST00000370399TGFBR3chr192187701-4076109592762917
ENST00000370812PIGKchr177587960-ENST00000525962TGFBR3chr192187701-4075109592765918
ENST00000445065PIGKchr177587960-ENST00000212355TGFBR3chr192187701-5882817132487824
ENST00000445065PIGKchr177587960-ENST00000370399TGFBR3chr192187701-3798817132484823
ENST00000445065PIGKchr177587960-ENST00000525962TGFBR3chr192187701-3797817132487824
ENST00000370813PIGKchr177587960-ENST00000212355TGFBR3chr192187701-5936871132541842
ENST00000370813PIGKchr177587960-ENST00000370399TGFBR3chr192187701-3852871132538841
ENST00000370813PIGKchr177587960-ENST00000525962TGFBR3chr192187701-3851871132541842

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000370812ENST00000212355PIGKchr177587960-TGFBR3chr192187701-4.83E-050.9999517
ENST00000370812ENST00000370399PIGKchr177587960-TGFBR3chr192187701-0.0001603720.99983954
ENST00000370812ENST00000525962PIGKchr177587960-TGFBR3chr192187701-0.0001496490.9998503
ENST00000445065ENST00000212355PIGKchr177587960-TGFBR3chr192187701-0.0001220460.9998779
ENST00000445065ENST00000370399PIGKchr177587960-TGFBR3chr192187701-0.0003559950.99964404
ENST00000445065ENST00000525962PIGKchr177587960-TGFBR3chr192187701-0.000413510.9995865
ENST00000370813ENST00000212355PIGKchr177587960-TGFBR3chr192187701-0.0001027990.99989724
ENST00000370813ENST00000370399PIGKchr177587960-TGFBR3chr192187701-0.0003538070.9996462
ENST00000370813ENST00000525962PIGKchr177587960-TGFBR3chr192187701-0.0003628220.9996371

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Fusion Genomic Features for PIGK-TGFBR3


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for PIGK-TGFBR3


check button Go to

FGviewer for the breakpoints of chr1:77587960-chr1:92187701

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePIGKchr1:77587960chr1:92187701ENST00000370812-1011311_321357.0396.0RegionNote=Essential for GPI attachment
TgeneTGFBR3chr1:77587960chr1:92187701ENST00000212355617455_730295.0852.0DomainZP
TgeneTGFBR3chr1:77587960chr1:92187701ENST00000370399718455_730295.0851.0DomainZP
TgeneTGFBR3chr1:77587960chr1:92187701ENST00000525962516455_730295.0852.0DomainZP
TgeneTGFBR3chr1:77587960chr1:92187701ENST00000212355617810_851295.0852.0Topological domainCytoplasmic
TgeneTGFBR3chr1:77587960chr1:92187701ENST00000370399718810_851295.0851.0Topological domainCytoplasmic
TgeneTGFBR3chr1:77587960chr1:92187701ENST00000525962516810_851295.0852.0Topological domainCytoplasmic
TgeneTGFBR3chr1:77587960chr1:92187701ENST00000212355617788_809295.0852.0TransmembraneHelical
TgeneTGFBR3chr1:77587960chr1:92187701ENST00000370399718788_809295.0851.0TransmembraneHelical
TgeneTGFBR3chr1:77587960chr1:92187701ENST00000525962516788_809295.0852.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePIGKchr1:77587960chr1:92187701ENST00000370812-101128_367357.0396.0Topological domainLumenal
HgenePIGKchr1:77587960chr1:92187701ENST00000370812-1011389_395357.0396.0Topological domainCytoplasmic
HgenePIGKchr1:77587960chr1:92187701ENST00000370812-1011368_388357.0396.0TransmembraneHelical
TgeneTGFBR3chr1:77587960chr1:92187701ENST0000021235561721_787295.0852.0Topological domainExtracellular
TgeneTGFBR3chr1:77587960chr1:92187701ENST0000037039971821_787295.0851.0Topological domainExtracellular
TgeneTGFBR3chr1:77587960chr1:92187701ENST0000052596251621_787295.0852.0Topological domainExtracellular


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Fusion Gene Sequence for PIGK-TGFBR3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000370812_ENST00000212355_TCGA-85-8582-01A_PIGK_chr1_77587960_-_TGFBR3_chr1_92187701_length(transcript)=6160nt_BP=1095nt
GCGGGAAGTCTGAAGCCGGTAAACATGGCCGTCACCGACAGCCTCAGCCGGGCTGCGACTGTCTTGGCAACTGTGTTGCTCTTGTCCTTC
GGCAGCGTGGCCGCTAGTCATATCGAGGATCAAGCAGAACAATTCTTTAGAAGTGGCCATACAAACAACTGGGCTGTTCTGGTGTGTACA
TCCCGATTCTGGTTTAATTATCGACATGTTGCAAATACCCTTTCTGTTTATAGAAGTGTCAAGAGGCTAGGTATTCCTGACAGTCACATT
GTCCTAATGCTTGCAGATGATATGGCCTGTAATCCTAGAAATCCCAAACCAGCTACAGTGTTTAGTCACAAGAATATGGAACTAAATGTG
TATGGAGATGATGTGGAAGTGGATTATAGAAGTTACGAGGTAACTGTGGAGAATTTTTTACGGGTATTAACTGGGAGGATCCCACCTAGT
ACTCCTCGGTCAAAACGTCTTCTTTCTGATGACAGAAGCAATATTCTAATTTATATGACAGGGCATGGTGGAAATGGTTTCTTAAAATTT
CAAGATTCTGAAGAAATTACCAACATAGAACTCGCGGATGCTTTTGAACAAATGTGGCAGAAAAGACGCTACAATGAGCTACTGTTTATT
ATTGATACTTGCCAAGGAGCATCCATGTATGAACGATTTTATTCTCCTAACATAATGGCTCTAGCTAGTAGTCAAGTGGGAGAAGATTCA
CTCTCGCATCAACCTGATCCTGCAATTGGAGTCCATCTTATGGATAGATACACATTTTATGTCTTGGAATTTTTGGAAGAAATTAACCCA
GCTAGCCAAACTAATATGAATGACCTTTTTCAGGTATGTCCCAAAAGTCTGTGTGTGTCTACTCCTGGACATCGCACTGATCTTTTTCAG
AGGGATCCTAAAAATGTACTGATAACTGATTTCTTTGGAAGTGTACGGAAAGTGGAAATTACAACAGAGACTATTAAATTGCAACAGGAT
TCAGAAATCATGGAAAGCAGCTATAAGGAAGACCAGATGGATGAGAAACTAATGGAACCTCTGAAATATGCTGAACAACTTCCTGTAGCT
CAGATAATACACCAGGCTCCTAACAGTATTGGCTTTGGAAAAGAGAGTGAAAGATCTATGACAATGACCAAATCAATAAGAGATGACATT
CCTTCAACCCAAGGGAATCTGGTGAAGTGGGCTTTGGACAATGGCTATAGTCCAATAACTTCATACACAATGGCTCCTGTGGCTAATAGA
TTTCATCTTCGGCTTGAAAATAATGCAGAGGAGATGGGAGATGAGGAAGTCCACACTATTCCTCCTGAGCTACGGATCCTGCTGGACCCT
GGTGCCCTGCCTGCCCTGCAGAACCCGCCCATCCGGGGAGGGGAAGGCCAAAATGGAGGCCTTCCGTTTCCTTTCCCAGATATTTCCAGG
AGAGTCTGGAATGAAGAGGGAGAAGATGGGCTCCCTCGGCCAAAGGACCCTGTCATTCCCAGCATACAACTGTTTCCTGGTCTCAGAGAG
CCAGAAGAGGTGCAAGGGAGCGTGGATATTGCCCTGTCTGTCAAATGTGACAATGAGAAGATGATCGTGGCTGTAGAAAAAGATTCTTTT
CAGGCCAGTGGCTACTCGGGGATGGACGTCACCCTGTTGGATCCTACCTGCAAGGCCAAGATGAATGGCACACACTTTGTTTTGGAGTCT
CCTCTGAATGGCTGCGGTACTCGGCCCCGGTGGTCAGCCCTTGATGGTGTGGTCTACTATAACTCCATTGTGATACAGGTTCCAGCCCTT
GGGGACAGTAGTGGTTGGCCAGATGGTTATGAAGATCTGGAGTCAGGTGATAATGGATTTCCGGGAGATATGGATGAAGGAGATGCTTCC
CTGTTCACCCGACCTGAAATCGTGGTGTTTAATTGCAGCCTTCAGCAGGTGAGGAACCCCAGCAGCTTCCAGGAACAGCCCCACGGAAAC
ATCACCTTCAACATGGAGCTATACAACACTGACCTCTTTTTGGTGCCCTCCCAGGGCGTCTTCTCTGTGCCAGAGAATGGACACGTTTAT
GTTGAGGTATCTGTTACTAAGGCTGAACAAGAACTGGGATTTGCCATCCAAACGTGCTTTATCTCTCCATATTCGAACCCTGATAGGATG
TCTCATTACACCATTATTGAGAATATTTGTCCTAAAGATGAATCTGTGAAATTCTACAGTCCCAAGAGAGTGCACTTTCCTATCCCGCAA
GCTGACATGGATAAGAAGCGATTCAGCTTTGTCTTCAAGCCTGTCTTCAACACCTCACTGCTCTTTCTACAGTGTGAGCTGACGCTGTGT
ACGAAGATGGAGAAGCACCCCCAGAAGTTGCCTAAGTGTGTGCCTCCTGACGAAGCCTGCACCTCGCTGGACGCCTCGATAATCTGGGCC
ATGATGCAGAATAAGAAGACGTTCACTAAGCCCCTTGCTGTGATCCACCATGAAGCAGAATCTAAAGAAAAAGGTCCAAGCATGAAGGAA
CCAAATCCAATTTCTCCACCAATTTTCCATGGTCTGGACACCCTAACCGTGATGGGCATTGCGTTTGCAGCCTTTGTGATCGGAGCACTC
CTGACGGGGGCCTTGTGGTACATCTATTCTCACACAGGGGAGACAGCAGGAAGGCAGCAAGTCCCCACCTCCCCGCCAGCCTCGGAAAAC
AGCAGTGCTGCCCACAGCATCGGCAGCACGCAGAGCACGCCTTGCTCCAGCAGCAGCACGGCCTAGCCCAACCCAGCCCAACCCGGCCCA
ACCCAGCCCAGCCCAGCTCAGCTCAGCTACTGCCAAGGGCAGGACCAATGGCTGAGCCTCGTGTCCAGACTCAGAGGGCTGGATTTTGGT
TCCCTTGTAAAGACAGAGTGAATTTCAGTATAAAGATCACCCGTTGTATTCACCCCACACCCAGGGCTAGTATAAACATGACCCTGGGCT
TCTGTACCACACTAGAATTCATGTGAGAAAGCTAAAATGGTGGTCTTCTCCACCAGCCCCTCACAGGCTTGGGGGTTTTCAATGTGAAAC
ACATGCCAGTTTTTAAAATGCTGCTTTGTCCAGGTGAGAACATCCATAATTTGGGGCCCTGAGTTTTACCCAGACTCAAGGAGTTGGTAA
AGGGTTAATAGCCAGATAGTAGAACCAGTGAGGAGATGCGGCCAAAGATTCTTTATATCTGAACCAAGATGTAAAACAAGAAATGCTTTG
AGGCTTTCTAAGCGATCCTCCTGTCTAATTTGCACCTTTGTCTGGATGCACACTTCTGACCTTGCTGCCACAACCTGTGGGGTCTGATGT
GTCCCTTGATGGGTGCTGCCCTCAGGGACTGCACCCTGACAAGTGTTAAGGCAACATTCCTTTCTTGTGCCCTGGGCCAAAACCAATGCT
GATGACCTTATCAGCTTCCTGTTTCTTCCCATACTTGCATACACCACTGCAAAATGTCTTAATGCAAATTTTGTATTTCTTACAGGCCTA
CAGAAATTGAAAATGACCAAAATCAGGAACCACAGATTTGTGCCCATTCCTAATATTTTGTTCTGCAAATTAATGTATAATTTGAGGTGA
AATTCAGTTATAAAGTCAAGGACGAATTTGCACAGTGATATATTTCTATGTGTATGCAAGTACAAGTATATAATATGTCACCTGGCACAT
TCATTTTCTCAGTTGAAGAAGAGAAAATTTGAAAATGTCCTTATGCTTTTAGAGTTGCAACTTAAGTATATTTGGTAGGGTGAGTGTTTC
CACTCAAAATATGTCAACTTAAAAAAAAATAGGCCCTTTCATAAAAACCAAACTGTAGCAAGATGCAAATGCATGGCAAATCCTGTCGGT
CTCCAGTTGGTTATCTGAATAGTGTCACCAATTCCACCAAGACAGTGCTGAGATTGGAAAAGGGCACTCATTTGGATTGCCTTACTTCTC
TTGCCTTAAATATATCCCATATATTTAATATGTCAAAAAGGGCTTGAGGTGAATTTCATTAAATGGAATAATATGATGCCACTTTGCAGC
TAAAATAAGCTCAGTGATACCTCCTTGTTAAAAAAAAAAAAAAAAAAAAAGAATGCCAGGGGGGAATTATCATGCTAAATTATTTTACTG
CTGAAGATAGCTTCATTGCAAATTATTCTTTTTCCAGAATTTCCCCCAAACAACTTAGAATTCCATAAGTAGAACAAGATAGATTCTACC
CCCAAAATATTCATAAGCAAATCCCACTGCCCTTAAAATAAGGAAGTTATGCCTGGTTGTCTGTGAATGGAACCTCAGTAGGTAATCCTG
ATGAAGCTTAAAACCTTAGGGCAGTGTCTACATGGGAAACAAGTATGTGGAAATTGACAATCATTTTTACCAAATCGTTGAGTAATAATA
TGACTTACCTGATAGATATACACATTCAATAAGGAACATTTTTTTTTTTCAATAAGGAACATTTTAACTAAAACATTACTTTAGGGCTGA
GATTTCCAGGCTATCTACATTGATCTACTGAAAAATTTCTAGATTTCCATATACAAACGAAGAAGACATGAGTTTAGAGAATTTTTTTCC
TTTAATTTTTTTTTAACAGAAGGGTATCAGAGTGGAGGACCTAGATTACGCTACCTGTGTTTGAAAATATTGCGCTTTGCCTAACCTTCG
GTGGAATGTATTGTTTCAGCATATTCTATGTATAAAAAAGTTTAAAGATGTCTTCAAAGAAGACTAGAGTCTTTAAGTCACTTATAGCTA
TATTTTACTACAAAATTTGTGTATAAAGATATATTTAAGTGTTTTAGATAAATTTAAGTTACTCCATATGAAATGTTTAATTTCAGCTAC
TGTGAATTCTTTCGATCAGTCCTTTGCTTTTTTAAAAAATCTTTTCCATCGTGTTAAAAAGAAAATTAGCTATTAGGAGATATTAAAAGA
TTGATGTCTTAGAAGGACAGGGTTAAAACCTTCTGTAATATATTTAAATATATATTTTTAAGAGAGATGCTACATTGCCAATGATTTTAT
AAATAATTTAAAATTAATTTACAAATTTATAGATGCAAACCAAAAGATCTTTTTAAAAGAGAGAGAGAGGAAAAAAATCACCTTTTATTT
GTTTGGGTCTCATTGTCAGAATTATTATTCAGATCAAGAAATCTGTGTCGATAAAACCTAATCTCATATTGGAGAGTGAATGTCGTTAAG
TATTTCTGAAATGTTTCTAAAAAATGAACATGAAAAAAATAAGGTATTTTCTCCCTAGCTTCTCATTACAGTATTTCTAATTGCTTCACA
CTTTACAGTTTTAATACAAAGTACAAGCTCTACTTTTATAACGTGTACTACAAGTTTCTTTAAAAGTATTGTTGTATTTCAGCTGAACTC
TTGTATCTGCAGTCTTTTGTTATTTCTGCAGGCTACACCCTTAATTTGCAGAGGCCATTTTGTTGTTTGTTTGATGCTGAAGCTGTTGTT
AAAATGCCCCAAACTCCAAGGCAGATTGTCTGTATAATACGCTATAGCTTTTCACCATGTGGTGTTTACCAGCTGTTACTCTGTATTTTA
AAAAGCCAGAGATTTCTTCTGTCTAAACTGTTTCTATAGCATTTTCTAAACAAAAAAAATGGTTTTTTTCTTTGCCTTGTAATAAGATTG
TAAATCCATTTCCTGCTTGTGTTCTTAGTGGGCATGATTGTGAGTGTGTGTGGGGTGCTCACACGCGTGCCAGTCTTTTTGTACTGTAAC
TACCTCATGGTTTGAATGATGATTGTACTGCTGGTTGTGTTAACAGAGCACATTTTGTTGGGTGAGTCCTATGTGATTTTTTTCATGTTT
GTTTTATCTGGGGGTTGTTCATGAAACTGACAGATGTTTTTCTAAAAAGGACTATTATCAGTTTCCAAATACAATACTTCTCTCTTCTGG
TTTTTCCTGAATGAGCCTGATTTTGTTGCTGGTTTTCATCATCTATGAGGGTAAAACGAGTACCCTTAAAATCCCTGTGGCCAGTTTGAA
CACCCCTGTTGTATTCTTTTCTCTGTTCAGTGTGTCAGCTATTTTGTGAAGATGCTTAGATGTATAGTTTTGATAACCACAGTTTTAAAT

>In-frame_ENST00000370812_ENST00000212355_TCGA-85-8582-01A_PIGK_chr1_77587960_-_TGFBR3_chr1_92187701_length(amino acids)=918AA_start in transcript=9_stop in transcript=2765
MKPVNMAVTDSLSRAATVLATVLLLSFGSVAASHIEDQAEQFFRSGHTNNWAVLVCTSRFWFNYRHVANTLSVYRSVKRLGIPDSHIVLM
LADDMACNPRNPKPATVFSHKNMELNVYGDDVEVDYRSYEVTVENFLRVLTGRIPPSTPRSKRLLSDDRSNILIYMTGHGGNGFLKFQDS
EEITNIELADAFEQMWQKRRYNELLFIIDTCQGASMYERFYSPNIMALASSQVGEDSLSHQPDPAIGVHLMDRYTFYVLEFLEEINPASQ
TNMNDLFQVCPKSLCVSTPGHRTDLFQRDPKNVLITDFFGSVRKVEITTETIKLQQDSEIMESSYKEDQMDEKLMEPLKYAEQLPVAQII
HQAPNSIGFGKESERSMTMTKSIRDDIPSTQGNLVKWALDNGYSPITSYTMAPVANRFHLRLENNAEEMGDEEVHTIPPELRILLDPGAL
PALQNPPIRGGEGQNGGLPFPFPDISRRVWNEEGEDGLPRPKDPVIPSIQLFPGLREPEEVQGSVDIALSVKCDNEKMIVAVEKDSFQAS
GYSGMDVTLLDPTCKAKMNGTHFVLESPLNGCGTRPRWSALDGVVYYNSIVIQVPALGDSSGWPDGYEDLESGDNGFPGDMDEGDASLFT
RPEIVVFNCSLQQVRNPSSFQEQPHGNITFNMELYNTDLFLVPSQGVFSVPENGHVYVEVSVTKAEQELGFAIQTCFISPYSNPDRMSHY
TIIENICPKDESVKFYSPKRVHFPIPQADMDKKRFSFVFKPVFNTSLLFLQCELTLCTKMEKHPQKLPKCVPPDEACTSLDASIIWAMMQ
NKKTFTKPLAVIHHEAESKEKGPSMKEPNPISPPIFHGLDTLTVMGIAFAAFVIGALLTGALWYIYSHTGETAGRQQVPTSPPASENSSA

--------------------------------------------------------------
>In-frame_ENST00000370812_ENST00000370399_TCGA-85-8582-01A_PIGK_chr1_77587960_-_TGFBR3_chr1_92187701_length(transcript)=4076nt_BP=1095nt
GCGGGAAGTCTGAAGCCGGTAAACATGGCCGTCACCGACAGCCTCAGCCGGGCTGCGACTGTCTTGGCAACTGTGTTGCTCTTGTCCTTC
GGCAGCGTGGCCGCTAGTCATATCGAGGATCAAGCAGAACAATTCTTTAGAAGTGGCCATACAAACAACTGGGCTGTTCTGGTGTGTACA
TCCCGATTCTGGTTTAATTATCGACATGTTGCAAATACCCTTTCTGTTTATAGAAGTGTCAAGAGGCTAGGTATTCCTGACAGTCACATT
GTCCTAATGCTTGCAGATGATATGGCCTGTAATCCTAGAAATCCCAAACCAGCTACAGTGTTTAGTCACAAGAATATGGAACTAAATGTG
TATGGAGATGATGTGGAAGTGGATTATAGAAGTTACGAGGTAACTGTGGAGAATTTTTTACGGGTATTAACTGGGAGGATCCCACCTAGT
ACTCCTCGGTCAAAACGTCTTCTTTCTGATGACAGAAGCAATATTCTAATTTATATGACAGGGCATGGTGGAAATGGTTTCTTAAAATTT
CAAGATTCTGAAGAAATTACCAACATAGAACTCGCGGATGCTTTTGAACAAATGTGGCAGAAAAGACGCTACAATGAGCTACTGTTTATT
ATTGATACTTGCCAAGGAGCATCCATGTATGAACGATTTTATTCTCCTAACATAATGGCTCTAGCTAGTAGTCAAGTGGGAGAAGATTCA
CTCTCGCATCAACCTGATCCTGCAATTGGAGTCCATCTTATGGATAGATACACATTTTATGTCTTGGAATTTTTGGAAGAAATTAACCCA
GCTAGCCAAACTAATATGAATGACCTTTTTCAGGTATGTCCCAAAAGTCTGTGTGTGTCTACTCCTGGACATCGCACTGATCTTTTTCAG
AGGGATCCTAAAAATGTACTGATAACTGATTTCTTTGGAAGTGTACGGAAAGTGGAAATTACAACAGAGACTATTAAATTGCAACAGGAT
TCAGAAATCATGGAAAGCAGCTATAAGGAAGACCAGATGGATGAGAAACTAATGGAACCTCTGAAATATGCTGAACAACTTCCTGTAGCT
CAGATAATACACCAGGCTCCTAACAGTATTGGCTTTGGAAAAGAGAGTGAAAGATCTATGACAATGACCAAATCAATAAGAGATGACATT
CCTTCAACCCAAGGGAATCTGGTGAAGTGGGCTTTGGACAATGGCTATAGTCCAATAACTTCATACACAATGGCTCCTGTGGCTAATAGA
TTTCATCTTCGGCTTGAAAATAATGAGGAGATGGGAGATGAGGAAGTCCACACTATTCCTCCTGAGCTACGGATCCTGCTGGACCCTGGT
GCCCTGCCTGCCCTGCAGAACCCGCCCATCCGGGGAGGGGAAGGCCAAAATGGAGGCCTTCCGTTTCCTTTCCCAGATATTTCCAGGAGA
GTCTGGAATGAAGAGGGAGAAGATGGGCTCCCTCGGCCAAAGGACCCTGTCATTCCCAGCATACAACTGTTTCCTGGTCTCAGAGAGCCA
GAAGAGGTGCAAGGGAGCGTGGATATTGCCCTGTCTGTCAAATGTGACAATGAGAAGATGATCGTGGCTGTAGAAAAAGATTCTTTTCAG
GCCAGTGGCTACTCGGGGATGGACGTCACCCTGTTGGATCCTACCTGCAAGGCCAAGATGAATGGCACACACTTTGTTTTGGAGTCTCCT
CTGAATGGCTGCGGTACTCGGCCCCGGTGGTCAGCCCTTGATGGTGTGGTCTACTATAACTCCATTGTGATACAGGTTCCAGCCCTTGGG
GACAGTAGTGGTTGGCCAGATGGTTATGAAGATCTGGAGTCAGGTGATAATGGATTTCCGGGAGATATGGATGAAGGAGATGCTTCCCTG
TTCACCCGACCTGAAATCGTGGTGTTTAATTGCAGCCTTCAGCAGGTGAGGAACCCCAGCAGCTTCCAGGAACAGCCCCACGGAAACATC
ACCTTCAACATGGAGCTATACAACACTGACCTCTTTTTGGTGCCCTCCCAGGGCGTCTTCTCTGTGCCAGAGAATGGACACGTTTATGTT
GAGGTATCTGTTACTAAGGCTGAACAAGAACTGGGATTTGCCATCCAAACGTGCTTTATCTCTCCATATTCGAACCCTGATAGGATGTCT
CATTACACCATTATTGAGAATATTTGTCCTAAAGATGAATCTGTGAAATTCTACAGTCCCAAGAGAGTGCACTTTCCTATCCCGCAAGCT
GACATGGATAAGAAGCGATTCAGCTTTGTCTTCAAGCCTGTCTTCAACACCTCACTGCTCTTTCTACAGTGTGAGCTGACGCTGTGTACG
AAGATGGAGAAGCACCCCCAGAAGTTGCCTAAGTGTGTGCCTCCTGACGAAGCCTGCACCTCGCTGGACGCCTCGATAATCTGGGCCATG
ATGCAGAATAAGAAGACGTTCACTAAGCCCCTTGCTGTGATCCACCATGAAGCAGAATCTAAAGAAAAAGGTCCAAGCATGAAGGAACCA
AATCCAATTTCTCCACCAATTTTCCATGGTCTGGACACCCTAACCGTGATGGGCATTGCGTTTGCAGCCTTTGTGATCGGAGCACTCCTG
ACGGGGGCCTTGTGGTACATCTATTCTCACACAGGGGAGACAGCAGGAAGGCAGCAAGTCCCCACCTCCCCGCCAGCCTCGGAAAACAGC
AGTGCTGCCCACAGCATCGGCAGCACGCAGAGCACGCCTTGCTCCAGCAGCAGCACGGCCTAGCCCAACCCAGCCCAACCCGGCCCAACC
CAGCCCAGCCCAGCTCAGCTCAGCTACTGCCAAGGGCAGGACCAATGGCTGAGCCTCGTGTCCAGACTCAGAGGGCTGGATTTTGGTTCC
CTTGTAAAGACAGAGTGAATTTCAGTATAAAGATCACCCGTTGTATTCACCCCACACCCAGGGCTAGTATAAACATGACCCTGGGCTTCT
GTACCACACTAGAATTCATGTGAGAAAGCTAAAATGGTGGTCTTCTCCACCAGCCCCTCACAGGCTTGGGGGTTTTCAATGTGAAACACA
TGCCAGTTTTTAAAATGCTGCTTTGTCCAGGTGAGAACATCCATAATTTGGGGCCCTGAGTTTTACCCAGACTCAAGGAGTTGGTAAAGG
GTTAATAGCCAGATAGTAGAACCAGTGAGGAGATGCGGCCAAAGATTCTTTATATCTGAACCAAGATGTAAAACAAGAAATGCTTTGAGG
CTTTCTAAGCGATCCTCCTGTCTAATTTGCACCTTTGTCTGGATGCACACTTCTGACCTTGCTGCCACAACCTGTGGGGTCTGATGTGTC
CCTTGATGGGTGCTGCCCTCAGGGACTGCACCCTGACAAGTGTTAAGGCAACATTCCTTTCTTGTGCCCTGGGCCAAAACCAATGCTGAT
GACCTTATCAGCTTCCTGTTTCTTCCCATACTTGCATACACCACTGCAAAATGTCTTAATGCAAATTTTGTATTTCTTACAGGCCTACAG
AAATTGAAAATGACCAAAATCAGGAACCACAGATTTGTGCCCATTCCTAATATTTTGTTCTGCAAATTAATGTATAATTTGAGGTGAAAT
TCAGTTATAAAGTCAAGGACGAATTTGCACAGTGATATATTTCTATGTGTATGCAAGTACAAGTATATAATATGTCACCTGGCACATTCA
TTTTCTCAGTTGAAGAAGAGAAAATTTGAAAATGTCCTTATGCTTTTAGAGTTGCAACTTAAGTATATTTGGTAGGGTGAGTGTTTCCAC
TCAAAATATGTCAACTTAAAAAAAAATAGGCCCTTTCATAAAAACCAAACTGTAGCAAGATGCAAATGCATGGCAAATCCTGTCGGTCTC
CAGTTGGTTATCTGAATAGTGTCACCAATTCCACCAAGACAGTGCTGAGATTGGAAAAGGGCACTCATTTGGATTGCCTTACTTCTCTTG
CCTTAAATATATCCCATATATTTAATATGTCAAAAAGGGCTTGAGGTGAATTTCATTAAATGGAATAATATGATGCCACTTTGCAGCTAA

>In-frame_ENST00000370812_ENST00000370399_TCGA-85-8582-01A_PIGK_chr1_77587960_-_TGFBR3_chr1_92187701_length(amino acids)=917AA_start in transcript=9_stop in transcript=2762
MKPVNMAVTDSLSRAATVLATVLLLSFGSVAASHIEDQAEQFFRSGHTNNWAVLVCTSRFWFNYRHVANTLSVYRSVKRLGIPDSHIVLM
LADDMACNPRNPKPATVFSHKNMELNVYGDDVEVDYRSYEVTVENFLRVLTGRIPPSTPRSKRLLSDDRSNILIYMTGHGGNGFLKFQDS
EEITNIELADAFEQMWQKRRYNELLFIIDTCQGASMYERFYSPNIMALASSQVGEDSLSHQPDPAIGVHLMDRYTFYVLEFLEEINPASQ
TNMNDLFQVCPKSLCVSTPGHRTDLFQRDPKNVLITDFFGSVRKVEITTETIKLQQDSEIMESSYKEDQMDEKLMEPLKYAEQLPVAQII
HQAPNSIGFGKESERSMTMTKSIRDDIPSTQGNLVKWALDNGYSPITSYTMAPVANRFHLRLENNEEMGDEEVHTIPPELRILLDPGALP
ALQNPPIRGGEGQNGGLPFPFPDISRRVWNEEGEDGLPRPKDPVIPSIQLFPGLREPEEVQGSVDIALSVKCDNEKMIVAVEKDSFQASG
YSGMDVTLLDPTCKAKMNGTHFVLESPLNGCGTRPRWSALDGVVYYNSIVIQVPALGDSSGWPDGYEDLESGDNGFPGDMDEGDASLFTR
PEIVVFNCSLQQVRNPSSFQEQPHGNITFNMELYNTDLFLVPSQGVFSVPENGHVYVEVSVTKAEQELGFAIQTCFISPYSNPDRMSHYT
IIENICPKDESVKFYSPKRVHFPIPQADMDKKRFSFVFKPVFNTSLLFLQCELTLCTKMEKHPQKLPKCVPPDEACTSLDASIIWAMMQN
KKTFTKPLAVIHHEAESKEKGPSMKEPNPISPPIFHGLDTLTVMGIAFAAFVIGALLTGALWYIYSHTGETAGRQQVPTSPPASENSSAA

--------------------------------------------------------------
>In-frame_ENST00000370812_ENST00000525962_TCGA-85-8582-01A_PIGK_chr1_77587960_-_TGFBR3_chr1_92187701_length(transcript)=4075nt_BP=1095nt
GCGGGAAGTCTGAAGCCGGTAAACATGGCCGTCACCGACAGCCTCAGCCGGGCTGCGACTGTCTTGGCAACTGTGTTGCTCTTGTCCTTC
GGCAGCGTGGCCGCTAGTCATATCGAGGATCAAGCAGAACAATTCTTTAGAAGTGGCCATACAAACAACTGGGCTGTTCTGGTGTGTACA
TCCCGATTCTGGTTTAATTATCGACATGTTGCAAATACCCTTTCTGTTTATAGAAGTGTCAAGAGGCTAGGTATTCCTGACAGTCACATT
GTCCTAATGCTTGCAGATGATATGGCCTGTAATCCTAGAAATCCCAAACCAGCTACAGTGTTTAGTCACAAGAATATGGAACTAAATGTG
TATGGAGATGATGTGGAAGTGGATTATAGAAGTTACGAGGTAACTGTGGAGAATTTTTTACGGGTATTAACTGGGAGGATCCCACCTAGT
ACTCCTCGGTCAAAACGTCTTCTTTCTGATGACAGAAGCAATATTCTAATTTATATGACAGGGCATGGTGGAAATGGTTTCTTAAAATTT
CAAGATTCTGAAGAAATTACCAACATAGAACTCGCGGATGCTTTTGAACAAATGTGGCAGAAAAGACGCTACAATGAGCTACTGTTTATT
ATTGATACTTGCCAAGGAGCATCCATGTATGAACGATTTTATTCTCCTAACATAATGGCTCTAGCTAGTAGTCAAGTGGGAGAAGATTCA
CTCTCGCATCAACCTGATCCTGCAATTGGAGTCCATCTTATGGATAGATACACATTTTATGTCTTGGAATTTTTGGAAGAAATTAACCCA
GCTAGCCAAACTAATATGAATGACCTTTTTCAGGTATGTCCCAAAAGTCTGTGTGTGTCTACTCCTGGACATCGCACTGATCTTTTTCAG
AGGGATCCTAAAAATGTACTGATAACTGATTTCTTTGGAAGTGTACGGAAAGTGGAAATTACAACAGAGACTATTAAATTGCAACAGGAT
TCAGAAATCATGGAAAGCAGCTATAAGGAAGACCAGATGGATGAGAAACTAATGGAACCTCTGAAATATGCTGAACAACTTCCTGTAGCT
CAGATAATACACCAGGCTCCTAACAGTATTGGCTTTGGAAAAGAGAGTGAAAGATCTATGACAATGACCAAATCAATAAGAGATGACATT
CCTTCAACCCAAGGGAATCTGGTGAAGTGGGCTTTGGACAATGGCTATAGTCCAATAACTTCATACACAATGGCTCCTGTGGCTAATAGA
TTTCATCTTCGGCTTGAAAATAATGCAGAGGAGATGGGAGATGAGGAAGTCCACACTATTCCTCCTGAGCTACGGATCCTGCTGGACCCT
GGTGCCCTGCCTGCCCTGCAGAACCCGCCCATCCGGGGAGGGGAAGGCCAAAATGGAGGCCTTCCGTTTCCTTTCCCAGATATTTCCAGG
AGAGTCTGGAATGAAGAGGGAGAAGATGGGCTCCCTCGGCCAAAGGACCCTGTCATTCCCAGCATACAACTGTTTCCTGGTCTCAGAGAG
CCAGAAGAGGTGCAAGGGAGCGTGGATATTGCCCTGTCTGTCAAATGTGACAATGAGAAGATGATCGTGGCTGTAGAAAAAGATTCTTTT
CAGGCCAGTGGCTACTCGGGGATGGACGTCACCCTGTTGGATCCTACCTGCAAGGCCAAGATGAATGGCACACACTTTGTTTTGGAGTCT
CCTCTGAATGGCTGCGGTACTCGGCCCCGGTGGTCAGCCCTTGATGGTGTGGTCTACTATAACTCCATTGTGATACAGGTTCCAGCCCTT
GGGGACAGTAGTGGTTGGCCAGATGGTTATGAAGATCTGGAGTCAGGTGATAATGGATTTCCGGGAGATATGGATGAAGGAGATGCTTCC
CTGTTCACCCGACCTGAAATCGTGGTGTTTAATTGCAGCCTTCAGCAGGTGAGGAACCCCAGCAGCTTCCAGGAACAGCCCCACGGAAAC
ATCACCTTCAACATGGAGCTATACAACACTGACCTCTTTTTGGTGCCCTCCCAGGGCGTCTTCTCTGTGCCAGAGAATGGACACGTTTAT
GTTGAGGTATCTGTTACTAAGGCTGAACAAGAACTGGGATTTGCCATCCAAACGTGCTTTATCTCTCCATATTCGAACCCTGATAGGATG
TCTCATTACACCATTATTGAGAATATTTGTCCTAAAGATGAATCTGTGAAATTCTACAGTCCCAAGAGAGTGCACTTTCCTATCCCGCAA
GCTGACATGGATAAGAAGCGATTCAGCTTTGTCTTCAAGCCTGTCTTCAACACCTCACTGCTCTTTCTACAGTGTGAGCTGACGCTGTGT
ACGAAGATGGAGAAGCACCCCCAGAAGTTGCCTAAGTGTGTGCCTCCTGACGAAGCCTGCACCTCGCTGGACGCCTCGATAATCTGGGCC
ATGATGCAGAATAAGAAGACGTTCACTAAGCCCCTTGCTGTGATCCACCATGAAGCAGAATCTAAAGAAAAAGGTCCAAGCATGAAGGAA
CCAAATCCAATTTCTCCACCAATTTTCCATGGTCTGGACACCCTAACCGTGATGGGCATTGCGTTTGCAGCCTTTGTGATCGGAGCACTC
CTGACGGGGGCCTTGTGGTACATCTATTCTCACACAGGGGAGACAGCAGGAAGGCAGCAAGTCCCCACCTCCCCGCCAGCCTCGGAAAAC
AGCAGTGCTGCCCACAGCATCGGCAGCACGCAGAGCACGCCTTGCTCCAGCAGCAGCACGGCCTAGCCCAACCCAGCCCAACCCGGCCCA
ACCCAGCCCAGCCCAGCTCAGCTCAGCTACTGCCAAGGGCAGGACCAATGGCTGAGCCTCGTGTCCAGACTCAGAGGGCTGGATTTTGGT
TCCCTTGTAAAGACAGAGTGAATTTCAGTATAAAGATCACCCGTTGTATTCACCCCACACCCAGGGCTAGTATAAACATGACCCTGGGCT
TCTGTACCACACTAGAATTCATGTGAGAAAGCTAAAATGGTGGTCTTCTCCACCAGCCCCTCACAGGCTTGGGGGTTTTCAATGTGAAAC
ACATGCCAGTTTTTAAAATGCTGCTTTGTCCAGGTGAGAACATCCATAATTTGGGGCCCTGAGTTTTACCCAGACTCAAGGAGTTGGTAA
AGGGTTAATAGCCAGATAGTAGAACCAGTGAGGAGATGCGGCCAAAGATTCTTTATATCTGAACCAAGATGTAAAACAAGAAATGCTTTG
AGGCTTTCTAAGCGATCCTCCTGTCTAATTTGCACCTTTGTCTGGATGCACACTTCTGACCTTGCTGCCACAACCTGTGGGGTCTGATGT
GTCCCTTGATGGGTGCTGCCCTCAGGGACTGCACCCTGACAAGTGTTAAGGCAACATTCCTTTCTTGTGCCCTGGGCCAAAACCAATGCT
GATGACCTTATCAGCTTCCTGTTTCTTCCCATACTTGCATACACCACTGCAAAATGTCTTAATGCAAATTTTGTATTTCTTACAGGCCTA
CAGAAATTGAAAATGACCAAAATCAGGAACCACAGATTTGTGCCCATTCCTAATATTTTGTTCTGCAAATTAATGTATAATTTGAGGTGA
AATTCAGTTATAAAGTCAAGGACGAATTTGCACAGTGATATATTTCTATGTGTATGCAAGTACAAGTATATAATATGTCACCTGGCACAT
TCATTTTCTCAGTTGAAGAAGAGAAAATTTGAAAATGTCCTTATGCTTTTAGAGTTGCAACTTAAGTATATTTGGTAGGGTGAGTGTTTC
CACTCAAAATATGTCAACTTAAAAAAAAATAGGCCCTTTCATAAAAACCAAACTGTAGCAAGATGCAAATGCATGGCAAATCCTGTCGGT
CTCCAGTTGGTTATCTGAATAGTGTCACCAATTCCACCAAGACAGTGCTGAGATTGGAAAAGGGCACTCATTTGGATTGCCTTACTTCTC
TTGCCTTAAATATATCCCATATATTTAATATGTCAAAAAGGGCTTGAGGTGAATTTCATTAAATGGAATAATATGATGCCACTTTGCAGC

>In-frame_ENST00000370812_ENST00000525962_TCGA-85-8582-01A_PIGK_chr1_77587960_-_TGFBR3_chr1_92187701_length(amino acids)=918AA_start in transcript=9_stop in transcript=2765
MKPVNMAVTDSLSRAATVLATVLLLSFGSVAASHIEDQAEQFFRSGHTNNWAVLVCTSRFWFNYRHVANTLSVYRSVKRLGIPDSHIVLM
LADDMACNPRNPKPATVFSHKNMELNVYGDDVEVDYRSYEVTVENFLRVLTGRIPPSTPRSKRLLSDDRSNILIYMTGHGGNGFLKFQDS
EEITNIELADAFEQMWQKRRYNELLFIIDTCQGASMYERFYSPNIMALASSQVGEDSLSHQPDPAIGVHLMDRYTFYVLEFLEEINPASQ
TNMNDLFQVCPKSLCVSTPGHRTDLFQRDPKNVLITDFFGSVRKVEITTETIKLQQDSEIMESSYKEDQMDEKLMEPLKYAEQLPVAQII
HQAPNSIGFGKESERSMTMTKSIRDDIPSTQGNLVKWALDNGYSPITSYTMAPVANRFHLRLENNAEEMGDEEVHTIPPELRILLDPGAL
PALQNPPIRGGEGQNGGLPFPFPDISRRVWNEEGEDGLPRPKDPVIPSIQLFPGLREPEEVQGSVDIALSVKCDNEKMIVAVEKDSFQAS
GYSGMDVTLLDPTCKAKMNGTHFVLESPLNGCGTRPRWSALDGVVYYNSIVIQVPALGDSSGWPDGYEDLESGDNGFPGDMDEGDASLFT
RPEIVVFNCSLQQVRNPSSFQEQPHGNITFNMELYNTDLFLVPSQGVFSVPENGHVYVEVSVTKAEQELGFAIQTCFISPYSNPDRMSHY
TIIENICPKDESVKFYSPKRVHFPIPQADMDKKRFSFVFKPVFNTSLLFLQCELTLCTKMEKHPQKLPKCVPPDEACTSLDASIIWAMMQ
NKKTFTKPLAVIHHEAESKEKGPSMKEPNPISPPIFHGLDTLTVMGIAFAAFVIGALLTGALWYIYSHTGETAGRQQVPTSPPASENSSA

--------------------------------------------------------------
>In-frame_ENST00000445065_ENST00000212355_TCGA-85-8582-01A_PIGK_chr1_77587960_-_TGFBR3_chr1_92187701_length(transcript)=5882nt_BP=817nt
AGGTGCGGGAAGTCTGAAGCCGGTAAACATGGCCGTCACCGACAGCCTCAGCCGGGCTGCGACTGTCTTGGCAACTGTGTTGCTCTTGTC
CTTCGGCAGCGTGGCCGCTAGTCATATCGAGGTAACTGTGGAGAATTTTTTACGGGTATTAACTGGGAGGATCCCACCTAGTACTCCTCG
GTCAAAACGTCTTCTTTCTGATGACAGAAGCAATATTCTAATTTATATGACAGGGCATGGTGGAAATGGTTTCTTAAAATTTCAAGATTC
TGAAGAAATTACCAACATAGAACTCGCGGATGCTTTTGAACAAATGTGGCAGAAAAGACGCTACAATGAGCTACTGTTTATTATTGATAC
TTGCCAAGGAGCATCCATGTATGAACGATTTTATTCTCCTAACATAATGGCTCTAGCTAGTAGTCAAGTGGGAGAAGATTCACTCTCGCA
TCAACCTGATCCTGCAATTGGAGTCCATCTTATGGATAGATACACATTTTATGTCTTGGAATTTTTGGAAGAAATTAACCCAGCTAGCCA
AACTAATATGAATGACCTTTTTCAGGTATGTCCCAAAAGTCTGTGTGTGTCTACTCCTGGACATCGCACTGATCTTTTTCAGAGGGATCC
TAAAAATGTACTGATAACTGATTTCTTTGGAAGTGTACGGAAAGTGGAAATTACAACAGAGACTATTAAATTGCAACAGGATTCAGAAAT
CATGGAAAGCAGCTATAAGGAAGACCAGATGGATGAGAAACTAATGGAACCTCTGAAATATGCTGAACAACTTCCTGTAGCTCAGATAAT
ACACCAGGCTCCTAACAGTATTGGCTTTGGAAAAGAGAGTGAAAGATCTATGACAATGACCAAATCAATAAGAGATGACATTCCTTCAAC
CCAAGGGAATCTGGTGAAGTGGGCTTTGGACAATGGCTATAGTCCAATAACTTCATACACAATGGCTCCTGTGGCTAATAGATTTCATCT
TCGGCTTGAAAATAATGCAGAGGAGATGGGAGATGAGGAAGTCCACACTATTCCTCCTGAGCTACGGATCCTGCTGGACCCTGGTGCCCT
GCCTGCCCTGCAGAACCCGCCCATCCGGGGAGGGGAAGGCCAAAATGGAGGCCTTCCGTTTCCTTTCCCAGATATTTCCAGGAGAGTCTG
GAATGAAGAGGGAGAAGATGGGCTCCCTCGGCCAAAGGACCCTGTCATTCCCAGCATACAACTGTTTCCTGGTCTCAGAGAGCCAGAAGA
GGTGCAAGGGAGCGTGGATATTGCCCTGTCTGTCAAATGTGACAATGAGAAGATGATCGTGGCTGTAGAAAAAGATTCTTTTCAGGCCAG
TGGCTACTCGGGGATGGACGTCACCCTGTTGGATCCTACCTGCAAGGCCAAGATGAATGGCACACACTTTGTTTTGGAGTCTCCTCTGAA
TGGCTGCGGTACTCGGCCCCGGTGGTCAGCCCTTGATGGTGTGGTCTACTATAACTCCATTGTGATACAGGTTCCAGCCCTTGGGGACAG
TAGTGGTTGGCCAGATGGTTATGAAGATCTGGAGTCAGGTGATAATGGATTTCCGGGAGATATGGATGAAGGAGATGCTTCCCTGTTCAC
CCGACCTGAAATCGTGGTGTTTAATTGCAGCCTTCAGCAGGTGAGGAACCCCAGCAGCTTCCAGGAACAGCCCCACGGAAACATCACCTT
CAACATGGAGCTATACAACACTGACCTCTTTTTGGTGCCCTCCCAGGGCGTCTTCTCTGTGCCAGAGAATGGACACGTTTATGTTGAGGT
ATCTGTTACTAAGGCTGAACAAGAACTGGGATTTGCCATCCAAACGTGCTTTATCTCTCCATATTCGAACCCTGATAGGATGTCTCATTA
CACCATTATTGAGAATATTTGTCCTAAAGATGAATCTGTGAAATTCTACAGTCCCAAGAGAGTGCACTTTCCTATCCCGCAAGCTGACAT
GGATAAGAAGCGATTCAGCTTTGTCTTCAAGCCTGTCTTCAACACCTCACTGCTCTTTCTACAGTGTGAGCTGACGCTGTGTACGAAGAT
GGAGAAGCACCCCCAGAAGTTGCCTAAGTGTGTGCCTCCTGACGAAGCCTGCACCTCGCTGGACGCCTCGATAATCTGGGCCATGATGCA
GAATAAGAAGACGTTCACTAAGCCCCTTGCTGTGATCCACCATGAAGCAGAATCTAAAGAAAAAGGTCCAAGCATGAAGGAACCAAATCC
AATTTCTCCACCAATTTTCCATGGTCTGGACACCCTAACCGTGATGGGCATTGCGTTTGCAGCCTTTGTGATCGGAGCACTCCTGACGGG
GGCCTTGTGGTACATCTATTCTCACACAGGGGAGACAGCAGGAAGGCAGCAAGTCCCCACCTCCCCGCCAGCCTCGGAAAACAGCAGTGC
TGCCCACAGCATCGGCAGCACGCAGAGCACGCCTTGCTCCAGCAGCAGCACGGCCTAGCCCAACCCAGCCCAACCCGGCCCAACCCAGCC
CAGCCCAGCTCAGCTCAGCTACTGCCAAGGGCAGGACCAATGGCTGAGCCTCGTGTCCAGACTCAGAGGGCTGGATTTTGGTTCCCTTGT
AAAGACAGAGTGAATTTCAGTATAAAGATCACCCGTTGTATTCACCCCACACCCAGGGCTAGTATAAACATGACCCTGGGCTTCTGTACC
ACACTAGAATTCATGTGAGAAAGCTAAAATGGTGGTCTTCTCCACCAGCCCCTCACAGGCTTGGGGGTTTTCAATGTGAAACACATGCCA
GTTTTTAAAATGCTGCTTTGTCCAGGTGAGAACATCCATAATTTGGGGCCCTGAGTTTTACCCAGACTCAAGGAGTTGGTAAAGGGTTAA
TAGCCAGATAGTAGAACCAGTGAGGAGATGCGGCCAAAGATTCTTTATATCTGAACCAAGATGTAAAACAAGAAATGCTTTGAGGCTTTC
TAAGCGATCCTCCTGTCTAATTTGCACCTTTGTCTGGATGCACACTTCTGACCTTGCTGCCACAACCTGTGGGGTCTGATGTGTCCCTTG
ATGGGTGCTGCCCTCAGGGACTGCACCCTGACAAGTGTTAAGGCAACATTCCTTTCTTGTGCCCTGGGCCAAAACCAATGCTGATGACCT
TATCAGCTTCCTGTTTCTTCCCATACTTGCATACACCACTGCAAAATGTCTTAATGCAAATTTTGTATTTCTTACAGGCCTACAGAAATT
GAAAATGACCAAAATCAGGAACCACAGATTTGTGCCCATTCCTAATATTTTGTTCTGCAAATTAATGTATAATTTGAGGTGAAATTCAGT
TATAAAGTCAAGGACGAATTTGCACAGTGATATATTTCTATGTGTATGCAAGTACAAGTATATAATATGTCACCTGGCACATTCATTTTC
TCAGTTGAAGAAGAGAAAATTTGAAAATGTCCTTATGCTTTTAGAGTTGCAACTTAAGTATATTTGGTAGGGTGAGTGTTTCCACTCAAA
ATATGTCAACTTAAAAAAAAATAGGCCCTTTCATAAAAACCAAACTGTAGCAAGATGCAAATGCATGGCAAATCCTGTCGGTCTCCAGTT
GGTTATCTGAATAGTGTCACCAATTCCACCAAGACAGTGCTGAGATTGGAAAAGGGCACTCATTTGGATTGCCTTACTTCTCTTGCCTTA
AATATATCCCATATATTTAATATGTCAAAAAGGGCTTGAGGTGAATTTCATTAAATGGAATAATATGATGCCACTTTGCAGCTAAAATAA
GCTCAGTGATACCTCCTTGTTAAAAAAAAAAAAAAAAAAAAAGAATGCCAGGGGGGAATTATCATGCTAAATTATTTTACTGCTGAAGAT
AGCTTCATTGCAAATTATTCTTTTTCCAGAATTTCCCCCAAACAACTTAGAATTCCATAAGTAGAACAAGATAGATTCTACCCCCAAAAT
ATTCATAAGCAAATCCCACTGCCCTTAAAATAAGGAAGTTATGCCTGGTTGTCTGTGAATGGAACCTCAGTAGGTAATCCTGATGAAGCT
TAAAACCTTAGGGCAGTGTCTACATGGGAAACAAGTATGTGGAAATTGACAATCATTTTTACCAAATCGTTGAGTAATAATATGACTTAC
CTGATAGATATACACATTCAATAAGGAACATTTTTTTTTTTCAATAAGGAACATTTTAACTAAAACATTACTTTAGGGCTGAGATTTCCA
GGCTATCTACATTGATCTACTGAAAAATTTCTAGATTTCCATATACAAACGAAGAAGACATGAGTTTAGAGAATTTTTTTCCTTTAATTT
TTTTTTAACAGAAGGGTATCAGAGTGGAGGACCTAGATTACGCTACCTGTGTTTGAAAATATTGCGCTTTGCCTAACCTTCGGTGGAATG
TATTGTTTCAGCATATTCTATGTATAAAAAAGTTTAAAGATGTCTTCAAAGAAGACTAGAGTCTTTAAGTCACTTATAGCTATATTTTAC
TACAAAATTTGTGTATAAAGATATATTTAAGTGTTTTAGATAAATTTAAGTTACTCCATATGAAATGTTTAATTTCAGCTACTGTGAATT
CTTTCGATCAGTCCTTTGCTTTTTTAAAAAATCTTTTCCATCGTGTTAAAAAGAAAATTAGCTATTAGGAGATATTAAAAGATTGATGTC
TTAGAAGGACAGGGTTAAAACCTTCTGTAATATATTTAAATATATATTTTTAAGAGAGATGCTACATTGCCAATGATTTTATAAATAATT
TAAAATTAATTTACAAATTTATAGATGCAAACCAAAAGATCTTTTTAAAAGAGAGAGAGAGGAAAAAAATCACCTTTTATTTGTTTGGGT
CTCATTGTCAGAATTATTATTCAGATCAAGAAATCTGTGTCGATAAAACCTAATCTCATATTGGAGAGTGAATGTCGTTAAGTATTTCTG
AAATGTTTCTAAAAAATGAACATGAAAAAAATAAGGTATTTTCTCCCTAGCTTCTCATTACAGTATTTCTAATTGCTTCACACTTTACAG
TTTTAATACAAAGTACAAGCTCTACTTTTATAACGTGTACTACAAGTTTCTTTAAAAGTATTGTTGTATTTCAGCTGAACTCTTGTATCT
GCAGTCTTTTGTTATTTCTGCAGGCTACACCCTTAATTTGCAGAGGCCATTTTGTTGTTTGTTTGATGCTGAAGCTGTTGTTAAAATGCC
CCAAACTCCAAGGCAGATTGTCTGTATAATACGCTATAGCTTTTCACCATGTGGTGTTTACCAGCTGTTACTCTGTATTTTAAAAAGCCA
GAGATTTCTTCTGTCTAAACTGTTTCTATAGCATTTTCTAAACAAAAAAAATGGTTTTTTTCTTTGCCTTGTAATAAGATTGTAAATCCA
TTTCCTGCTTGTGTTCTTAGTGGGCATGATTGTGAGTGTGTGTGGGGTGCTCACACGCGTGCCAGTCTTTTTGTACTGTAACTACCTCAT
GGTTTGAATGATGATTGTACTGCTGGTTGTGTTAACAGAGCACATTTTGTTGGGTGAGTCCTATGTGATTTTTTTCATGTTTGTTTTATC
TGGGGGTTGTTCATGAAACTGACAGATGTTTTTCTAAAAAGGACTATTATCAGTTTCCAAATACAATACTTCTCTCTTCTGGTTTTTCCT
GAATGAGCCTGATTTTGTTGCTGGTTTTCATCATCTATGAGGGTAAAACGAGTACCCTTAAAATCCCTGTGGCCAGTTTGAACACCCCTG
TTGTATTCTTTTCTCTGTTCAGTGTGTCAGCTATTTTGTGAAGATGCTTAGATGTATAGTTTTGATAACCACAGTTTTAAATCTTTTATC

>In-frame_ENST00000445065_ENST00000212355_TCGA-85-8582-01A_PIGK_chr1_77587960_-_TGFBR3_chr1_92187701_length(amino acids)=824AA_start in transcript=13_stop in transcript=2487
MKPVNMAVTDSLSRAATVLATVLLLSFGSVAASHIEVTVENFLRVLTGRIPPSTPRSKRLLSDDRSNILIYMTGHGGNGFLKFQDSEEIT
NIELADAFEQMWQKRRYNELLFIIDTCQGASMYERFYSPNIMALASSQVGEDSLSHQPDPAIGVHLMDRYTFYVLEFLEEINPASQTNMN
DLFQVCPKSLCVSTPGHRTDLFQRDPKNVLITDFFGSVRKVEITTETIKLQQDSEIMESSYKEDQMDEKLMEPLKYAEQLPVAQIIHQAP
NSIGFGKESERSMTMTKSIRDDIPSTQGNLVKWALDNGYSPITSYTMAPVANRFHLRLENNAEEMGDEEVHTIPPELRILLDPGALPALQ
NPPIRGGEGQNGGLPFPFPDISRRVWNEEGEDGLPRPKDPVIPSIQLFPGLREPEEVQGSVDIALSVKCDNEKMIVAVEKDSFQASGYSG
MDVTLLDPTCKAKMNGTHFVLESPLNGCGTRPRWSALDGVVYYNSIVIQVPALGDSSGWPDGYEDLESGDNGFPGDMDEGDASLFTRPEI
VVFNCSLQQVRNPSSFQEQPHGNITFNMELYNTDLFLVPSQGVFSVPENGHVYVEVSVTKAEQELGFAIQTCFISPYSNPDRMSHYTIIE
NICPKDESVKFYSPKRVHFPIPQADMDKKRFSFVFKPVFNTSLLFLQCELTLCTKMEKHPQKLPKCVPPDEACTSLDASIIWAMMQNKKT
FTKPLAVIHHEAESKEKGPSMKEPNPISPPIFHGLDTLTVMGIAFAAFVIGALLTGALWYIYSHTGETAGRQQVPTSPPASENSSAAHSI

--------------------------------------------------------------
>In-frame_ENST00000445065_ENST00000370399_TCGA-85-8582-01A_PIGK_chr1_77587960_-_TGFBR3_chr1_92187701_length(transcript)=3798nt_BP=817nt
AGGTGCGGGAAGTCTGAAGCCGGTAAACATGGCCGTCACCGACAGCCTCAGCCGGGCTGCGACTGTCTTGGCAACTGTGTTGCTCTTGTC
CTTCGGCAGCGTGGCCGCTAGTCATATCGAGGTAACTGTGGAGAATTTTTTACGGGTATTAACTGGGAGGATCCCACCTAGTACTCCTCG
GTCAAAACGTCTTCTTTCTGATGACAGAAGCAATATTCTAATTTATATGACAGGGCATGGTGGAAATGGTTTCTTAAAATTTCAAGATTC
TGAAGAAATTACCAACATAGAACTCGCGGATGCTTTTGAACAAATGTGGCAGAAAAGACGCTACAATGAGCTACTGTTTATTATTGATAC
TTGCCAAGGAGCATCCATGTATGAACGATTTTATTCTCCTAACATAATGGCTCTAGCTAGTAGTCAAGTGGGAGAAGATTCACTCTCGCA
TCAACCTGATCCTGCAATTGGAGTCCATCTTATGGATAGATACACATTTTATGTCTTGGAATTTTTGGAAGAAATTAACCCAGCTAGCCA
AACTAATATGAATGACCTTTTTCAGGTATGTCCCAAAAGTCTGTGTGTGTCTACTCCTGGACATCGCACTGATCTTTTTCAGAGGGATCC
TAAAAATGTACTGATAACTGATTTCTTTGGAAGTGTACGGAAAGTGGAAATTACAACAGAGACTATTAAATTGCAACAGGATTCAGAAAT
CATGGAAAGCAGCTATAAGGAAGACCAGATGGATGAGAAACTAATGGAACCTCTGAAATATGCTGAACAACTTCCTGTAGCTCAGATAAT
ACACCAGGCTCCTAACAGTATTGGCTTTGGAAAAGAGAGTGAAAGATCTATGACAATGACCAAATCAATAAGAGATGACATTCCTTCAAC
CCAAGGGAATCTGGTGAAGTGGGCTTTGGACAATGGCTATAGTCCAATAACTTCATACACAATGGCTCCTGTGGCTAATAGATTTCATCT
TCGGCTTGAAAATAATGAGGAGATGGGAGATGAGGAAGTCCACACTATTCCTCCTGAGCTACGGATCCTGCTGGACCCTGGTGCCCTGCC
TGCCCTGCAGAACCCGCCCATCCGGGGAGGGGAAGGCCAAAATGGAGGCCTTCCGTTTCCTTTCCCAGATATTTCCAGGAGAGTCTGGAA
TGAAGAGGGAGAAGATGGGCTCCCTCGGCCAAAGGACCCTGTCATTCCCAGCATACAACTGTTTCCTGGTCTCAGAGAGCCAGAAGAGGT
GCAAGGGAGCGTGGATATTGCCCTGTCTGTCAAATGTGACAATGAGAAGATGATCGTGGCTGTAGAAAAAGATTCTTTTCAGGCCAGTGG
CTACTCGGGGATGGACGTCACCCTGTTGGATCCTACCTGCAAGGCCAAGATGAATGGCACACACTTTGTTTTGGAGTCTCCTCTGAATGG
CTGCGGTACTCGGCCCCGGTGGTCAGCCCTTGATGGTGTGGTCTACTATAACTCCATTGTGATACAGGTTCCAGCCCTTGGGGACAGTAG
TGGTTGGCCAGATGGTTATGAAGATCTGGAGTCAGGTGATAATGGATTTCCGGGAGATATGGATGAAGGAGATGCTTCCCTGTTCACCCG
ACCTGAAATCGTGGTGTTTAATTGCAGCCTTCAGCAGGTGAGGAACCCCAGCAGCTTCCAGGAACAGCCCCACGGAAACATCACCTTCAA
CATGGAGCTATACAACACTGACCTCTTTTTGGTGCCCTCCCAGGGCGTCTTCTCTGTGCCAGAGAATGGACACGTTTATGTTGAGGTATC
TGTTACTAAGGCTGAACAAGAACTGGGATTTGCCATCCAAACGTGCTTTATCTCTCCATATTCGAACCCTGATAGGATGTCTCATTACAC
CATTATTGAGAATATTTGTCCTAAAGATGAATCTGTGAAATTCTACAGTCCCAAGAGAGTGCACTTTCCTATCCCGCAAGCTGACATGGA
TAAGAAGCGATTCAGCTTTGTCTTCAAGCCTGTCTTCAACACCTCACTGCTCTTTCTACAGTGTGAGCTGACGCTGTGTACGAAGATGGA
GAAGCACCCCCAGAAGTTGCCTAAGTGTGTGCCTCCTGACGAAGCCTGCACCTCGCTGGACGCCTCGATAATCTGGGCCATGATGCAGAA
TAAGAAGACGTTCACTAAGCCCCTTGCTGTGATCCACCATGAAGCAGAATCTAAAGAAAAAGGTCCAAGCATGAAGGAACCAAATCCAAT
TTCTCCACCAATTTTCCATGGTCTGGACACCCTAACCGTGATGGGCATTGCGTTTGCAGCCTTTGTGATCGGAGCACTCCTGACGGGGGC
CTTGTGGTACATCTATTCTCACACAGGGGAGACAGCAGGAAGGCAGCAAGTCCCCACCTCCCCGCCAGCCTCGGAAAACAGCAGTGCTGC
CCACAGCATCGGCAGCACGCAGAGCACGCCTTGCTCCAGCAGCAGCACGGCCTAGCCCAACCCAGCCCAACCCGGCCCAACCCAGCCCAG
CCCAGCTCAGCTCAGCTACTGCCAAGGGCAGGACCAATGGCTGAGCCTCGTGTCCAGACTCAGAGGGCTGGATTTTGGTTCCCTTGTAAA
GACAGAGTGAATTTCAGTATAAAGATCACCCGTTGTATTCACCCCACACCCAGGGCTAGTATAAACATGACCCTGGGCTTCTGTACCACA
CTAGAATTCATGTGAGAAAGCTAAAATGGTGGTCTTCTCCACCAGCCCCTCACAGGCTTGGGGGTTTTCAATGTGAAACACATGCCAGTT
TTTAAAATGCTGCTTTGTCCAGGTGAGAACATCCATAATTTGGGGCCCTGAGTTTTACCCAGACTCAAGGAGTTGGTAAAGGGTTAATAG
CCAGATAGTAGAACCAGTGAGGAGATGCGGCCAAAGATTCTTTATATCTGAACCAAGATGTAAAACAAGAAATGCTTTGAGGCTTTCTAA
GCGATCCTCCTGTCTAATTTGCACCTTTGTCTGGATGCACACTTCTGACCTTGCTGCCACAACCTGTGGGGTCTGATGTGTCCCTTGATG
GGTGCTGCCCTCAGGGACTGCACCCTGACAAGTGTTAAGGCAACATTCCTTTCTTGTGCCCTGGGCCAAAACCAATGCTGATGACCTTAT
CAGCTTCCTGTTTCTTCCCATACTTGCATACACCACTGCAAAATGTCTTAATGCAAATTTTGTATTTCTTACAGGCCTACAGAAATTGAA
AATGACCAAAATCAGGAACCACAGATTTGTGCCCATTCCTAATATTTTGTTCTGCAAATTAATGTATAATTTGAGGTGAAATTCAGTTAT
AAAGTCAAGGACGAATTTGCACAGTGATATATTTCTATGTGTATGCAAGTACAAGTATATAATATGTCACCTGGCACATTCATTTTCTCA
GTTGAAGAAGAGAAAATTTGAAAATGTCCTTATGCTTTTAGAGTTGCAACTTAAGTATATTTGGTAGGGTGAGTGTTTCCACTCAAAATA
TGTCAACTTAAAAAAAAATAGGCCCTTTCATAAAAACCAAACTGTAGCAAGATGCAAATGCATGGCAAATCCTGTCGGTCTCCAGTTGGT
TATCTGAATAGTGTCACCAATTCCACCAAGACAGTGCTGAGATTGGAAAAGGGCACTCATTTGGATTGCCTTACTTCTCTTGCCTTAAAT
ATATCCCATATATTTAATATGTCAAAAAGGGCTTGAGGTGAATTTCATTAAATGGAATAATATGATGCCACTTTGCAGCTAAAATAAGCT

>In-frame_ENST00000445065_ENST00000370399_TCGA-85-8582-01A_PIGK_chr1_77587960_-_TGFBR3_chr1_92187701_length(amino acids)=823AA_start in transcript=13_stop in transcript=2484
MKPVNMAVTDSLSRAATVLATVLLLSFGSVAASHIEVTVENFLRVLTGRIPPSTPRSKRLLSDDRSNILIYMTGHGGNGFLKFQDSEEIT
NIELADAFEQMWQKRRYNELLFIIDTCQGASMYERFYSPNIMALASSQVGEDSLSHQPDPAIGVHLMDRYTFYVLEFLEEINPASQTNMN
DLFQVCPKSLCVSTPGHRTDLFQRDPKNVLITDFFGSVRKVEITTETIKLQQDSEIMESSYKEDQMDEKLMEPLKYAEQLPVAQIIHQAP
NSIGFGKESERSMTMTKSIRDDIPSTQGNLVKWALDNGYSPITSYTMAPVANRFHLRLENNEEMGDEEVHTIPPELRILLDPGALPALQN
PPIRGGEGQNGGLPFPFPDISRRVWNEEGEDGLPRPKDPVIPSIQLFPGLREPEEVQGSVDIALSVKCDNEKMIVAVEKDSFQASGYSGM
DVTLLDPTCKAKMNGTHFVLESPLNGCGTRPRWSALDGVVYYNSIVIQVPALGDSSGWPDGYEDLESGDNGFPGDMDEGDASLFTRPEIV
VFNCSLQQVRNPSSFQEQPHGNITFNMELYNTDLFLVPSQGVFSVPENGHVYVEVSVTKAEQELGFAIQTCFISPYSNPDRMSHYTIIEN
ICPKDESVKFYSPKRVHFPIPQADMDKKRFSFVFKPVFNTSLLFLQCELTLCTKMEKHPQKLPKCVPPDEACTSLDASIIWAMMQNKKTF
TKPLAVIHHEAESKEKGPSMKEPNPISPPIFHGLDTLTVMGIAFAAFVIGALLTGALWYIYSHTGETAGRQQVPTSPPASENSSAAHSIG

--------------------------------------------------------------
>In-frame_ENST00000445065_ENST00000525962_TCGA-85-8582-01A_PIGK_chr1_77587960_-_TGFBR3_chr1_92187701_length(transcript)=3797nt_BP=817nt
AGGTGCGGGAAGTCTGAAGCCGGTAAACATGGCCGTCACCGACAGCCTCAGCCGGGCTGCGACTGTCTTGGCAACTGTGTTGCTCTTGTC
CTTCGGCAGCGTGGCCGCTAGTCATATCGAGGTAACTGTGGAGAATTTTTTACGGGTATTAACTGGGAGGATCCCACCTAGTACTCCTCG
GTCAAAACGTCTTCTTTCTGATGACAGAAGCAATATTCTAATTTATATGACAGGGCATGGTGGAAATGGTTTCTTAAAATTTCAAGATTC
TGAAGAAATTACCAACATAGAACTCGCGGATGCTTTTGAACAAATGTGGCAGAAAAGACGCTACAATGAGCTACTGTTTATTATTGATAC
TTGCCAAGGAGCATCCATGTATGAACGATTTTATTCTCCTAACATAATGGCTCTAGCTAGTAGTCAAGTGGGAGAAGATTCACTCTCGCA
TCAACCTGATCCTGCAATTGGAGTCCATCTTATGGATAGATACACATTTTATGTCTTGGAATTTTTGGAAGAAATTAACCCAGCTAGCCA
AACTAATATGAATGACCTTTTTCAGGTATGTCCCAAAAGTCTGTGTGTGTCTACTCCTGGACATCGCACTGATCTTTTTCAGAGGGATCC
TAAAAATGTACTGATAACTGATTTCTTTGGAAGTGTACGGAAAGTGGAAATTACAACAGAGACTATTAAATTGCAACAGGATTCAGAAAT
CATGGAAAGCAGCTATAAGGAAGACCAGATGGATGAGAAACTAATGGAACCTCTGAAATATGCTGAACAACTTCCTGTAGCTCAGATAAT
ACACCAGGCTCCTAACAGTATTGGCTTTGGAAAAGAGAGTGAAAGATCTATGACAATGACCAAATCAATAAGAGATGACATTCCTTCAAC
CCAAGGGAATCTGGTGAAGTGGGCTTTGGACAATGGCTATAGTCCAATAACTTCATACACAATGGCTCCTGTGGCTAATAGATTTCATCT
TCGGCTTGAAAATAATGCAGAGGAGATGGGAGATGAGGAAGTCCACACTATTCCTCCTGAGCTACGGATCCTGCTGGACCCTGGTGCCCT
GCCTGCCCTGCAGAACCCGCCCATCCGGGGAGGGGAAGGCCAAAATGGAGGCCTTCCGTTTCCTTTCCCAGATATTTCCAGGAGAGTCTG
GAATGAAGAGGGAGAAGATGGGCTCCCTCGGCCAAAGGACCCTGTCATTCCCAGCATACAACTGTTTCCTGGTCTCAGAGAGCCAGAAGA
GGTGCAAGGGAGCGTGGATATTGCCCTGTCTGTCAAATGTGACAATGAGAAGATGATCGTGGCTGTAGAAAAAGATTCTTTTCAGGCCAG
TGGCTACTCGGGGATGGACGTCACCCTGTTGGATCCTACCTGCAAGGCCAAGATGAATGGCACACACTTTGTTTTGGAGTCTCCTCTGAA
TGGCTGCGGTACTCGGCCCCGGTGGTCAGCCCTTGATGGTGTGGTCTACTATAACTCCATTGTGATACAGGTTCCAGCCCTTGGGGACAG
TAGTGGTTGGCCAGATGGTTATGAAGATCTGGAGTCAGGTGATAATGGATTTCCGGGAGATATGGATGAAGGAGATGCTTCCCTGTTCAC
CCGACCTGAAATCGTGGTGTTTAATTGCAGCCTTCAGCAGGTGAGGAACCCCAGCAGCTTCCAGGAACAGCCCCACGGAAACATCACCTT
CAACATGGAGCTATACAACACTGACCTCTTTTTGGTGCCCTCCCAGGGCGTCTTCTCTGTGCCAGAGAATGGACACGTTTATGTTGAGGT
ATCTGTTACTAAGGCTGAACAAGAACTGGGATTTGCCATCCAAACGTGCTTTATCTCTCCATATTCGAACCCTGATAGGATGTCTCATTA
CACCATTATTGAGAATATTTGTCCTAAAGATGAATCTGTGAAATTCTACAGTCCCAAGAGAGTGCACTTTCCTATCCCGCAAGCTGACAT
GGATAAGAAGCGATTCAGCTTTGTCTTCAAGCCTGTCTTCAACACCTCACTGCTCTTTCTACAGTGTGAGCTGACGCTGTGTACGAAGAT
GGAGAAGCACCCCCAGAAGTTGCCTAAGTGTGTGCCTCCTGACGAAGCCTGCACCTCGCTGGACGCCTCGATAATCTGGGCCATGATGCA
GAATAAGAAGACGTTCACTAAGCCCCTTGCTGTGATCCACCATGAAGCAGAATCTAAAGAAAAAGGTCCAAGCATGAAGGAACCAAATCC
AATTTCTCCACCAATTTTCCATGGTCTGGACACCCTAACCGTGATGGGCATTGCGTTTGCAGCCTTTGTGATCGGAGCACTCCTGACGGG
GGCCTTGTGGTACATCTATTCTCACACAGGGGAGACAGCAGGAAGGCAGCAAGTCCCCACCTCCCCGCCAGCCTCGGAAAACAGCAGTGC
TGCCCACAGCATCGGCAGCACGCAGAGCACGCCTTGCTCCAGCAGCAGCACGGCCTAGCCCAACCCAGCCCAACCCGGCCCAACCCAGCC
CAGCCCAGCTCAGCTCAGCTACTGCCAAGGGCAGGACCAATGGCTGAGCCTCGTGTCCAGACTCAGAGGGCTGGATTTTGGTTCCCTTGT
AAAGACAGAGTGAATTTCAGTATAAAGATCACCCGTTGTATTCACCCCACACCCAGGGCTAGTATAAACATGACCCTGGGCTTCTGTACC
ACACTAGAATTCATGTGAGAAAGCTAAAATGGTGGTCTTCTCCACCAGCCCCTCACAGGCTTGGGGGTTTTCAATGTGAAACACATGCCA
GTTTTTAAAATGCTGCTTTGTCCAGGTGAGAACATCCATAATTTGGGGCCCTGAGTTTTACCCAGACTCAAGGAGTTGGTAAAGGGTTAA
TAGCCAGATAGTAGAACCAGTGAGGAGATGCGGCCAAAGATTCTTTATATCTGAACCAAGATGTAAAACAAGAAATGCTTTGAGGCTTTC
TAAGCGATCCTCCTGTCTAATTTGCACCTTTGTCTGGATGCACACTTCTGACCTTGCTGCCACAACCTGTGGGGTCTGATGTGTCCCTTG
ATGGGTGCTGCCCTCAGGGACTGCACCCTGACAAGTGTTAAGGCAACATTCCTTTCTTGTGCCCTGGGCCAAAACCAATGCTGATGACCT
TATCAGCTTCCTGTTTCTTCCCATACTTGCATACACCACTGCAAAATGTCTTAATGCAAATTTTGTATTTCTTACAGGCCTACAGAAATT
GAAAATGACCAAAATCAGGAACCACAGATTTGTGCCCATTCCTAATATTTTGTTCTGCAAATTAATGTATAATTTGAGGTGAAATTCAGT
TATAAAGTCAAGGACGAATTTGCACAGTGATATATTTCTATGTGTATGCAAGTACAAGTATATAATATGTCACCTGGCACATTCATTTTC
TCAGTTGAAGAAGAGAAAATTTGAAAATGTCCTTATGCTTTTAGAGTTGCAACTTAAGTATATTTGGTAGGGTGAGTGTTTCCACTCAAA
ATATGTCAACTTAAAAAAAAATAGGCCCTTTCATAAAAACCAAACTGTAGCAAGATGCAAATGCATGGCAAATCCTGTCGGTCTCCAGTT
GGTTATCTGAATAGTGTCACCAATTCCACCAAGACAGTGCTGAGATTGGAAAAGGGCACTCATTTGGATTGCCTTACTTCTCTTGCCTTA
AATATATCCCATATATTTAATATGTCAAAAAGGGCTTGAGGTGAATTTCATTAAATGGAATAATATGATGCCACTTTGCAGCTAAAATAA

>In-frame_ENST00000445065_ENST00000525962_TCGA-85-8582-01A_PIGK_chr1_77587960_-_TGFBR3_chr1_92187701_length(amino acids)=824AA_start in transcript=13_stop in transcript=2487
MKPVNMAVTDSLSRAATVLATVLLLSFGSVAASHIEVTVENFLRVLTGRIPPSTPRSKRLLSDDRSNILIYMTGHGGNGFLKFQDSEEIT
NIELADAFEQMWQKRRYNELLFIIDTCQGASMYERFYSPNIMALASSQVGEDSLSHQPDPAIGVHLMDRYTFYVLEFLEEINPASQTNMN
DLFQVCPKSLCVSTPGHRTDLFQRDPKNVLITDFFGSVRKVEITTETIKLQQDSEIMESSYKEDQMDEKLMEPLKYAEQLPVAQIIHQAP
NSIGFGKESERSMTMTKSIRDDIPSTQGNLVKWALDNGYSPITSYTMAPVANRFHLRLENNAEEMGDEEVHTIPPELRILLDPGALPALQ
NPPIRGGEGQNGGLPFPFPDISRRVWNEEGEDGLPRPKDPVIPSIQLFPGLREPEEVQGSVDIALSVKCDNEKMIVAVEKDSFQASGYSG
MDVTLLDPTCKAKMNGTHFVLESPLNGCGTRPRWSALDGVVYYNSIVIQVPALGDSSGWPDGYEDLESGDNGFPGDMDEGDASLFTRPEI
VVFNCSLQQVRNPSSFQEQPHGNITFNMELYNTDLFLVPSQGVFSVPENGHVYVEVSVTKAEQELGFAIQTCFISPYSNPDRMSHYTIIE
NICPKDESVKFYSPKRVHFPIPQADMDKKRFSFVFKPVFNTSLLFLQCELTLCTKMEKHPQKLPKCVPPDEACTSLDASIIWAMMQNKKT
FTKPLAVIHHEAESKEKGPSMKEPNPISPPIFHGLDTLTVMGIAFAAFVIGALLTGALWYIYSHTGETAGRQQVPTSPPASENSSAAHSI

--------------------------------------------------------------
>In-frame_ENST00000370813_ENST00000212355_TCGA-85-8582-01A_PIGK_chr1_77587960_-_TGFBR3_chr1_92187701_length(transcript)=5936nt_BP=871nt
AGGTGCGGGAAGTCTGAAGCCGGTAAACATGGCCGTCACCGACAGCCTCAGCCGGGCTGCGACTGTCTTGGCAACTGTGTTGCTCTTGTC
CTTCGGCAGCGTGGCCGCTAGTCATATCGAGGATCAAGCAGAACAATTCTTTAGAAGTGGCCATACAAACAACTGGGCTGTTCTGGTAAC
TGTGGAGAATTTTTTACGGGTATTAACTGGGAGGATCCCACCTAGTACTCCTCGGTCAAAACGTCTTCTTTCTGATGACAGAAGCAATAT
TCTAATTTATATGACAGGGCATGGTGGAAATGGTTTCTTAAAATTTCAAGATTCTGAAGAAATTACCAACATAGAACTCGCGGATGCTTT
TGAACAAATGTGGCAGAAAAGACGCTACAATGAGCTACTGTTTATTATTGATACTTGCCAAGGAGCATCCATGTATGAACGATTTTATTC
TCCTAACATAATGGCTCTAGCTAGTAGTCAAGTGGGAGAAGATTCACTCTCGCATCAACCTGATCCTGCAATTGGAGTCCATCTTATGGA
TAGATACACATTTTATGTCTTGGAATTTTTGGAAGAAATTAACCCAGCTAGCCAAACTAATATGAATGACCTTTTTCAGGTATGTCCCAA
AAGTCTGTGTGTGTCTACTCCTGGACATCGCACTGATCTTTTTCAGAGGGATCCTAAAAATGTACTGATAACTGATTTCTTTGGAAGTGT
ACGGAAAGTGGAAATTACAACAGAGACTATTAAATTGCAACAGGATTCAGAAATCATGGAAAGCAGCTATAAGGAAGACCAGATGGATGA
GAAACTAATGGAACCTCTGAAATATGCTGAACAACTTCCTGTAGCTCAGATAATACACCAGGCTCCTAACAGTATTGGCTTTGGAAAAGA
GAGTGAAAGATCTATGACAATGACCAAATCAATAAGAGATGACATTCCTTCAACCCAAGGGAATCTGGTGAAGTGGGCTTTGGACAATGG
CTATAGTCCAATAACTTCATACACAATGGCTCCTGTGGCTAATAGATTTCATCTTCGGCTTGAAAATAATGCAGAGGAGATGGGAGATGA
GGAAGTCCACACTATTCCTCCTGAGCTACGGATCCTGCTGGACCCTGGTGCCCTGCCTGCCCTGCAGAACCCGCCCATCCGGGGAGGGGA
AGGCCAAAATGGAGGCCTTCCGTTTCCTTTCCCAGATATTTCCAGGAGAGTCTGGAATGAAGAGGGAGAAGATGGGCTCCCTCGGCCAAA
GGACCCTGTCATTCCCAGCATACAACTGTTTCCTGGTCTCAGAGAGCCAGAAGAGGTGCAAGGGAGCGTGGATATTGCCCTGTCTGTCAA
ATGTGACAATGAGAAGATGATCGTGGCTGTAGAAAAAGATTCTTTTCAGGCCAGTGGCTACTCGGGGATGGACGTCACCCTGTTGGATCC
TACCTGCAAGGCCAAGATGAATGGCACACACTTTGTTTTGGAGTCTCCTCTGAATGGCTGCGGTACTCGGCCCCGGTGGTCAGCCCTTGA
TGGTGTGGTCTACTATAACTCCATTGTGATACAGGTTCCAGCCCTTGGGGACAGTAGTGGTTGGCCAGATGGTTATGAAGATCTGGAGTC
AGGTGATAATGGATTTCCGGGAGATATGGATGAAGGAGATGCTTCCCTGTTCACCCGACCTGAAATCGTGGTGTTTAATTGCAGCCTTCA
GCAGGTGAGGAACCCCAGCAGCTTCCAGGAACAGCCCCACGGAAACATCACCTTCAACATGGAGCTATACAACACTGACCTCTTTTTGGT
GCCCTCCCAGGGCGTCTTCTCTGTGCCAGAGAATGGACACGTTTATGTTGAGGTATCTGTTACTAAGGCTGAACAAGAACTGGGATTTGC
CATCCAAACGTGCTTTATCTCTCCATATTCGAACCCTGATAGGATGTCTCATTACACCATTATTGAGAATATTTGTCCTAAAGATGAATC
TGTGAAATTCTACAGTCCCAAGAGAGTGCACTTTCCTATCCCGCAAGCTGACATGGATAAGAAGCGATTCAGCTTTGTCTTCAAGCCTGT
CTTCAACACCTCACTGCTCTTTCTACAGTGTGAGCTGACGCTGTGTACGAAGATGGAGAAGCACCCCCAGAAGTTGCCTAAGTGTGTGCC
TCCTGACGAAGCCTGCACCTCGCTGGACGCCTCGATAATCTGGGCCATGATGCAGAATAAGAAGACGTTCACTAAGCCCCTTGCTGTGAT
CCACCATGAAGCAGAATCTAAAGAAAAAGGTCCAAGCATGAAGGAACCAAATCCAATTTCTCCACCAATTTTCCATGGTCTGGACACCCT
AACCGTGATGGGCATTGCGTTTGCAGCCTTTGTGATCGGAGCACTCCTGACGGGGGCCTTGTGGTACATCTATTCTCACACAGGGGAGAC
AGCAGGAAGGCAGCAAGTCCCCACCTCCCCGCCAGCCTCGGAAAACAGCAGTGCTGCCCACAGCATCGGCAGCACGCAGAGCACGCCTTG
CTCCAGCAGCAGCACGGCCTAGCCCAACCCAGCCCAACCCGGCCCAACCCAGCCCAGCCCAGCTCAGCTCAGCTACTGCCAAGGGCAGGA
CCAATGGCTGAGCCTCGTGTCCAGACTCAGAGGGCTGGATTTTGGTTCCCTTGTAAAGACAGAGTGAATTTCAGTATAAAGATCACCCGT
TGTATTCACCCCACACCCAGGGCTAGTATAAACATGACCCTGGGCTTCTGTACCACACTAGAATTCATGTGAGAAAGCTAAAATGGTGGT
CTTCTCCACCAGCCCCTCACAGGCTTGGGGGTTTTCAATGTGAAACACATGCCAGTTTTTAAAATGCTGCTTTGTCCAGGTGAGAACATC
CATAATTTGGGGCCCTGAGTTTTACCCAGACTCAAGGAGTTGGTAAAGGGTTAATAGCCAGATAGTAGAACCAGTGAGGAGATGCGGCCA
AAGATTCTTTATATCTGAACCAAGATGTAAAACAAGAAATGCTTTGAGGCTTTCTAAGCGATCCTCCTGTCTAATTTGCACCTTTGTCTG
GATGCACACTTCTGACCTTGCTGCCACAACCTGTGGGGTCTGATGTGTCCCTTGATGGGTGCTGCCCTCAGGGACTGCACCCTGACAAGT
GTTAAGGCAACATTCCTTTCTTGTGCCCTGGGCCAAAACCAATGCTGATGACCTTATCAGCTTCCTGTTTCTTCCCATACTTGCATACAC
CACTGCAAAATGTCTTAATGCAAATTTTGTATTTCTTACAGGCCTACAGAAATTGAAAATGACCAAAATCAGGAACCACAGATTTGTGCC
CATTCCTAATATTTTGTTCTGCAAATTAATGTATAATTTGAGGTGAAATTCAGTTATAAAGTCAAGGACGAATTTGCACAGTGATATATT
TCTATGTGTATGCAAGTACAAGTATATAATATGTCACCTGGCACATTCATTTTCTCAGTTGAAGAAGAGAAAATTTGAAAATGTCCTTAT
GCTTTTAGAGTTGCAACTTAAGTATATTTGGTAGGGTGAGTGTTTCCACTCAAAATATGTCAACTTAAAAAAAAATAGGCCCTTTCATAA
AAACCAAACTGTAGCAAGATGCAAATGCATGGCAAATCCTGTCGGTCTCCAGTTGGTTATCTGAATAGTGTCACCAATTCCACCAAGACA
GTGCTGAGATTGGAAAAGGGCACTCATTTGGATTGCCTTACTTCTCTTGCCTTAAATATATCCCATATATTTAATATGTCAAAAAGGGCT
TGAGGTGAATTTCATTAAATGGAATAATATGATGCCACTTTGCAGCTAAAATAAGCTCAGTGATACCTCCTTGTTAAAAAAAAAAAAAAA
AAAAAAGAATGCCAGGGGGGAATTATCATGCTAAATTATTTTACTGCTGAAGATAGCTTCATTGCAAATTATTCTTTTTCCAGAATTTCC
CCCAAACAACTTAGAATTCCATAAGTAGAACAAGATAGATTCTACCCCCAAAATATTCATAAGCAAATCCCACTGCCCTTAAAATAAGGA
AGTTATGCCTGGTTGTCTGTGAATGGAACCTCAGTAGGTAATCCTGATGAAGCTTAAAACCTTAGGGCAGTGTCTACATGGGAAACAAGT
ATGTGGAAATTGACAATCATTTTTACCAAATCGTTGAGTAATAATATGACTTACCTGATAGATATACACATTCAATAAGGAACATTTTTT
TTTTTCAATAAGGAACATTTTAACTAAAACATTACTTTAGGGCTGAGATTTCCAGGCTATCTACATTGATCTACTGAAAAATTTCTAGAT
TTCCATATACAAACGAAGAAGACATGAGTTTAGAGAATTTTTTTCCTTTAATTTTTTTTTAACAGAAGGGTATCAGAGTGGAGGACCTAG
ATTACGCTACCTGTGTTTGAAAATATTGCGCTTTGCCTAACCTTCGGTGGAATGTATTGTTTCAGCATATTCTATGTATAAAAAAGTTTA
AAGATGTCTTCAAAGAAGACTAGAGTCTTTAAGTCACTTATAGCTATATTTTACTACAAAATTTGTGTATAAAGATATATTTAAGTGTTT
TAGATAAATTTAAGTTACTCCATATGAAATGTTTAATTTCAGCTACTGTGAATTCTTTCGATCAGTCCTTTGCTTTTTTAAAAAATCTTT
TCCATCGTGTTAAAAAGAAAATTAGCTATTAGGAGATATTAAAAGATTGATGTCTTAGAAGGACAGGGTTAAAACCTTCTGTAATATATT
TAAATATATATTTTTAAGAGAGATGCTACATTGCCAATGATTTTATAAATAATTTAAAATTAATTTACAAATTTATAGATGCAAACCAAA
AGATCTTTTTAAAAGAGAGAGAGAGGAAAAAAATCACCTTTTATTTGTTTGGGTCTCATTGTCAGAATTATTATTCAGATCAAGAAATCT
GTGTCGATAAAACCTAATCTCATATTGGAGAGTGAATGTCGTTAAGTATTTCTGAAATGTTTCTAAAAAATGAACATGAAAAAAATAAGG
TATTTTCTCCCTAGCTTCTCATTACAGTATTTCTAATTGCTTCACACTTTACAGTTTTAATACAAAGTACAAGCTCTACTTTTATAACGT
GTACTACAAGTTTCTTTAAAAGTATTGTTGTATTTCAGCTGAACTCTTGTATCTGCAGTCTTTTGTTATTTCTGCAGGCTACACCCTTAA
TTTGCAGAGGCCATTTTGTTGTTTGTTTGATGCTGAAGCTGTTGTTAAAATGCCCCAAACTCCAAGGCAGATTGTCTGTATAATACGCTA
TAGCTTTTCACCATGTGGTGTTTACCAGCTGTTACTCTGTATTTTAAAAAGCCAGAGATTTCTTCTGTCTAAACTGTTTCTATAGCATTT
TCTAAACAAAAAAAATGGTTTTTTTCTTTGCCTTGTAATAAGATTGTAAATCCATTTCCTGCTTGTGTTCTTAGTGGGCATGATTGTGAG
TGTGTGTGGGGTGCTCACACGCGTGCCAGTCTTTTTGTACTGTAACTACCTCATGGTTTGAATGATGATTGTACTGCTGGTTGTGTTAAC
AGAGCACATTTTGTTGGGTGAGTCCTATGTGATTTTTTTCATGTTTGTTTTATCTGGGGGTTGTTCATGAAACTGACAGATGTTTTTCTA
AAAAGGACTATTATCAGTTTCCAAATACAATACTTCTCTCTTCTGGTTTTTCCTGAATGAGCCTGATTTTGTTGCTGGTTTTCATCATCT
ATGAGGGTAAAACGAGTACCCTTAAAATCCCTGTGGCCAGTTTGAACACCCCTGTTGTATTCTTTTCTCTGTTCAGTGTGTCAGCTATTT

>In-frame_ENST00000370813_ENST00000212355_TCGA-85-8582-01A_PIGK_chr1_77587960_-_TGFBR3_chr1_92187701_length(amino acids)=842AA_start in transcript=13_stop in transcript=2541
MKPVNMAVTDSLSRAATVLATVLLLSFGSVAASHIEDQAEQFFRSGHTNNWAVLVTVENFLRVLTGRIPPSTPRSKRLLSDDRSNILIYM
TGHGGNGFLKFQDSEEITNIELADAFEQMWQKRRYNELLFIIDTCQGASMYERFYSPNIMALASSQVGEDSLSHQPDPAIGVHLMDRYTF
YVLEFLEEINPASQTNMNDLFQVCPKSLCVSTPGHRTDLFQRDPKNVLITDFFGSVRKVEITTETIKLQQDSEIMESSYKEDQMDEKLME
PLKYAEQLPVAQIIHQAPNSIGFGKESERSMTMTKSIRDDIPSTQGNLVKWALDNGYSPITSYTMAPVANRFHLRLENNAEEMGDEEVHT
IPPELRILLDPGALPALQNPPIRGGEGQNGGLPFPFPDISRRVWNEEGEDGLPRPKDPVIPSIQLFPGLREPEEVQGSVDIALSVKCDNE
KMIVAVEKDSFQASGYSGMDVTLLDPTCKAKMNGTHFVLESPLNGCGTRPRWSALDGVVYYNSIVIQVPALGDSSGWPDGYEDLESGDNG
FPGDMDEGDASLFTRPEIVVFNCSLQQVRNPSSFQEQPHGNITFNMELYNTDLFLVPSQGVFSVPENGHVYVEVSVTKAEQELGFAIQTC
FISPYSNPDRMSHYTIIENICPKDESVKFYSPKRVHFPIPQADMDKKRFSFVFKPVFNTSLLFLQCELTLCTKMEKHPQKLPKCVPPDEA
CTSLDASIIWAMMQNKKTFTKPLAVIHHEAESKEKGPSMKEPNPISPPIFHGLDTLTVMGIAFAAFVIGALLTGALWYIYSHTGETAGRQ

--------------------------------------------------------------
>In-frame_ENST00000370813_ENST00000370399_TCGA-85-8582-01A_PIGK_chr1_77587960_-_TGFBR3_chr1_92187701_length(transcript)=3852nt_BP=871nt
AGGTGCGGGAAGTCTGAAGCCGGTAAACATGGCCGTCACCGACAGCCTCAGCCGGGCTGCGACTGTCTTGGCAACTGTGTTGCTCTTGTC
CTTCGGCAGCGTGGCCGCTAGTCATATCGAGGATCAAGCAGAACAATTCTTTAGAAGTGGCCATACAAACAACTGGGCTGTTCTGGTAAC
TGTGGAGAATTTTTTACGGGTATTAACTGGGAGGATCCCACCTAGTACTCCTCGGTCAAAACGTCTTCTTTCTGATGACAGAAGCAATAT
TCTAATTTATATGACAGGGCATGGTGGAAATGGTTTCTTAAAATTTCAAGATTCTGAAGAAATTACCAACATAGAACTCGCGGATGCTTT
TGAACAAATGTGGCAGAAAAGACGCTACAATGAGCTACTGTTTATTATTGATACTTGCCAAGGAGCATCCATGTATGAACGATTTTATTC
TCCTAACATAATGGCTCTAGCTAGTAGTCAAGTGGGAGAAGATTCACTCTCGCATCAACCTGATCCTGCAATTGGAGTCCATCTTATGGA
TAGATACACATTTTATGTCTTGGAATTTTTGGAAGAAATTAACCCAGCTAGCCAAACTAATATGAATGACCTTTTTCAGGTATGTCCCAA
AAGTCTGTGTGTGTCTACTCCTGGACATCGCACTGATCTTTTTCAGAGGGATCCTAAAAATGTACTGATAACTGATTTCTTTGGAAGTGT
ACGGAAAGTGGAAATTACAACAGAGACTATTAAATTGCAACAGGATTCAGAAATCATGGAAAGCAGCTATAAGGAAGACCAGATGGATGA
GAAACTAATGGAACCTCTGAAATATGCTGAACAACTTCCTGTAGCTCAGATAATACACCAGGCTCCTAACAGTATTGGCTTTGGAAAAGA
GAGTGAAAGATCTATGACAATGACCAAATCAATAAGAGATGACATTCCTTCAACCCAAGGGAATCTGGTGAAGTGGGCTTTGGACAATGG
CTATAGTCCAATAACTTCATACACAATGGCTCCTGTGGCTAATAGATTTCATCTTCGGCTTGAAAATAATGAGGAGATGGGAGATGAGGA
AGTCCACACTATTCCTCCTGAGCTACGGATCCTGCTGGACCCTGGTGCCCTGCCTGCCCTGCAGAACCCGCCCATCCGGGGAGGGGAAGG
CCAAAATGGAGGCCTTCCGTTTCCTTTCCCAGATATTTCCAGGAGAGTCTGGAATGAAGAGGGAGAAGATGGGCTCCCTCGGCCAAAGGA
CCCTGTCATTCCCAGCATACAACTGTTTCCTGGTCTCAGAGAGCCAGAAGAGGTGCAAGGGAGCGTGGATATTGCCCTGTCTGTCAAATG
TGACAATGAGAAGATGATCGTGGCTGTAGAAAAAGATTCTTTTCAGGCCAGTGGCTACTCGGGGATGGACGTCACCCTGTTGGATCCTAC
CTGCAAGGCCAAGATGAATGGCACACACTTTGTTTTGGAGTCTCCTCTGAATGGCTGCGGTACTCGGCCCCGGTGGTCAGCCCTTGATGG
TGTGGTCTACTATAACTCCATTGTGATACAGGTTCCAGCCCTTGGGGACAGTAGTGGTTGGCCAGATGGTTATGAAGATCTGGAGTCAGG
TGATAATGGATTTCCGGGAGATATGGATGAAGGAGATGCTTCCCTGTTCACCCGACCTGAAATCGTGGTGTTTAATTGCAGCCTTCAGCA
GGTGAGGAACCCCAGCAGCTTCCAGGAACAGCCCCACGGAAACATCACCTTCAACATGGAGCTATACAACACTGACCTCTTTTTGGTGCC
CTCCCAGGGCGTCTTCTCTGTGCCAGAGAATGGACACGTTTATGTTGAGGTATCTGTTACTAAGGCTGAACAAGAACTGGGATTTGCCAT
CCAAACGTGCTTTATCTCTCCATATTCGAACCCTGATAGGATGTCTCATTACACCATTATTGAGAATATTTGTCCTAAAGATGAATCTGT
GAAATTCTACAGTCCCAAGAGAGTGCACTTTCCTATCCCGCAAGCTGACATGGATAAGAAGCGATTCAGCTTTGTCTTCAAGCCTGTCTT
CAACACCTCACTGCTCTTTCTACAGTGTGAGCTGACGCTGTGTACGAAGATGGAGAAGCACCCCCAGAAGTTGCCTAAGTGTGTGCCTCC
TGACGAAGCCTGCACCTCGCTGGACGCCTCGATAATCTGGGCCATGATGCAGAATAAGAAGACGTTCACTAAGCCCCTTGCTGTGATCCA
CCATGAAGCAGAATCTAAAGAAAAAGGTCCAAGCATGAAGGAACCAAATCCAATTTCTCCACCAATTTTCCATGGTCTGGACACCCTAAC
CGTGATGGGCATTGCGTTTGCAGCCTTTGTGATCGGAGCACTCCTGACGGGGGCCTTGTGGTACATCTATTCTCACACAGGGGAGACAGC
AGGAAGGCAGCAAGTCCCCACCTCCCCGCCAGCCTCGGAAAACAGCAGTGCTGCCCACAGCATCGGCAGCACGCAGAGCACGCCTTGCTC
CAGCAGCAGCACGGCCTAGCCCAACCCAGCCCAACCCGGCCCAACCCAGCCCAGCCCAGCTCAGCTCAGCTACTGCCAAGGGCAGGACCA
ATGGCTGAGCCTCGTGTCCAGACTCAGAGGGCTGGATTTTGGTTCCCTTGTAAAGACAGAGTGAATTTCAGTATAAAGATCACCCGTTGT
ATTCACCCCACACCCAGGGCTAGTATAAACATGACCCTGGGCTTCTGTACCACACTAGAATTCATGTGAGAAAGCTAAAATGGTGGTCTT
CTCCACCAGCCCCTCACAGGCTTGGGGGTTTTCAATGTGAAACACATGCCAGTTTTTAAAATGCTGCTTTGTCCAGGTGAGAACATCCAT
AATTTGGGGCCCTGAGTTTTACCCAGACTCAAGGAGTTGGTAAAGGGTTAATAGCCAGATAGTAGAACCAGTGAGGAGATGCGGCCAAAG
ATTCTTTATATCTGAACCAAGATGTAAAACAAGAAATGCTTTGAGGCTTTCTAAGCGATCCTCCTGTCTAATTTGCACCTTTGTCTGGAT
GCACACTTCTGACCTTGCTGCCACAACCTGTGGGGTCTGATGTGTCCCTTGATGGGTGCTGCCCTCAGGGACTGCACCCTGACAAGTGTT
AAGGCAACATTCCTTTCTTGTGCCCTGGGCCAAAACCAATGCTGATGACCTTATCAGCTTCCTGTTTCTTCCCATACTTGCATACACCAC
TGCAAAATGTCTTAATGCAAATTTTGTATTTCTTACAGGCCTACAGAAATTGAAAATGACCAAAATCAGGAACCACAGATTTGTGCCCAT
TCCTAATATTTTGTTCTGCAAATTAATGTATAATTTGAGGTGAAATTCAGTTATAAAGTCAAGGACGAATTTGCACAGTGATATATTTCT
ATGTGTATGCAAGTACAAGTATATAATATGTCACCTGGCACATTCATTTTCTCAGTTGAAGAAGAGAAAATTTGAAAATGTCCTTATGCT
TTTAGAGTTGCAACTTAAGTATATTTGGTAGGGTGAGTGTTTCCACTCAAAATATGTCAACTTAAAAAAAAATAGGCCCTTTCATAAAAA
CCAAACTGTAGCAAGATGCAAATGCATGGCAAATCCTGTCGGTCTCCAGTTGGTTATCTGAATAGTGTCACCAATTCCACCAAGACAGTG
CTGAGATTGGAAAAGGGCACTCATTTGGATTGCCTTACTTCTCTTGCCTTAAATATATCCCATATATTTAATATGTCAAAAAGGGCTTGA

>In-frame_ENST00000370813_ENST00000370399_TCGA-85-8582-01A_PIGK_chr1_77587960_-_TGFBR3_chr1_92187701_length(amino acids)=841AA_start in transcript=13_stop in transcript=2538
MKPVNMAVTDSLSRAATVLATVLLLSFGSVAASHIEDQAEQFFRSGHTNNWAVLVTVENFLRVLTGRIPPSTPRSKRLLSDDRSNILIYM
TGHGGNGFLKFQDSEEITNIELADAFEQMWQKRRYNELLFIIDTCQGASMYERFYSPNIMALASSQVGEDSLSHQPDPAIGVHLMDRYTF
YVLEFLEEINPASQTNMNDLFQVCPKSLCVSTPGHRTDLFQRDPKNVLITDFFGSVRKVEITTETIKLQQDSEIMESSYKEDQMDEKLME
PLKYAEQLPVAQIIHQAPNSIGFGKESERSMTMTKSIRDDIPSTQGNLVKWALDNGYSPITSYTMAPVANRFHLRLENNEEMGDEEVHTI
PPELRILLDPGALPALQNPPIRGGEGQNGGLPFPFPDISRRVWNEEGEDGLPRPKDPVIPSIQLFPGLREPEEVQGSVDIALSVKCDNEK
MIVAVEKDSFQASGYSGMDVTLLDPTCKAKMNGTHFVLESPLNGCGTRPRWSALDGVVYYNSIVIQVPALGDSSGWPDGYEDLESGDNGF
PGDMDEGDASLFTRPEIVVFNCSLQQVRNPSSFQEQPHGNITFNMELYNTDLFLVPSQGVFSVPENGHVYVEVSVTKAEQELGFAIQTCF
ISPYSNPDRMSHYTIIENICPKDESVKFYSPKRVHFPIPQADMDKKRFSFVFKPVFNTSLLFLQCELTLCTKMEKHPQKLPKCVPPDEAC
TSLDASIIWAMMQNKKTFTKPLAVIHHEAESKEKGPSMKEPNPISPPIFHGLDTLTVMGIAFAAFVIGALLTGALWYIYSHTGETAGRQQ

--------------------------------------------------------------
>In-frame_ENST00000370813_ENST00000525962_TCGA-85-8582-01A_PIGK_chr1_77587960_-_TGFBR3_chr1_92187701_length(transcript)=3851nt_BP=871nt
AGGTGCGGGAAGTCTGAAGCCGGTAAACATGGCCGTCACCGACAGCCTCAGCCGGGCTGCGACTGTCTTGGCAACTGTGTTGCTCTTGTC
CTTCGGCAGCGTGGCCGCTAGTCATATCGAGGATCAAGCAGAACAATTCTTTAGAAGTGGCCATACAAACAACTGGGCTGTTCTGGTAAC
TGTGGAGAATTTTTTACGGGTATTAACTGGGAGGATCCCACCTAGTACTCCTCGGTCAAAACGTCTTCTTTCTGATGACAGAAGCAATAT
TCTAATTTATATGACAGGGCATGGTGGAAATGGTTTCTTAAAATTTCAAGATTCTGAAGAAATTACCAACATAGAACTCGCGGATGCTTT
TGAACAAATGTGGCAGAAAAGACGCTACAATGAGCTACTGTTTATTATTGATACTTGCCAAGGAGCATCCATGTATGAACGATTTTATTC
TCCTAACATAATGGCTCTAGCTAGTAGTCAAGTGGGAGAAGATTCACTCTCGCATCAACCTGATCCTGCAATTGGAGTCCATCTTATGGA
TAGATACACATTTTATGTCTTGGAATTTTTGGAAGAAATTAACCCAGCTAGCCAAACTAATATGAATGACCTTTTTCAGGTATGTCCCAA
AAGTCTGTGTGTGTCTACTCCTGGACATCGCACTGATCTTTTTCAGAGGGATCCTAAAAATGTACTGATAACTGATTTCTTTGGAAGTGT
ACGGAAAGTGGAAATTACAACAGAGACTATTAAATTGCAACAGGATTCAGAAATCATGGAAAGCAGCTATAAGGAAGACCAGATGGATGA
GAAACTAATGGAACCTCTGAAATATGCTGAACAACTTCCTGTAGCTCAGATAATACACCAGGCTCCTAACAGTATTGGCTTTGGAAAAGA
GAGTGAAAGATCTATGACAATGACCAAATCAATAAGAGATGACATTCCTTCAACCCAAGGGAATCTGGTGAAGTGGGCTTTGGACAATGG
CTATAGTCCAATAACTTCATACACAATGGCTCCTGTGGCTAATAGATTTCATCTTCGGCTTGAAAATAATGCAGAGGAGATGGGAGATGA
GGAAGTCCACACTATTCCTCCTGAGCTACGGATCCTGCTGGACCCTGGTGCCCTGCCTGCCCTGCAGAACCCGCCCATCCGGGGAGGGGA
AGGCCAAAATGGAGGCCTTCCGTTTCCTTTCCCAGATATTTCCAGGAGAGTCTGGAATGAAGAGGGAGAAGATGGGCTCCCTCGGCCAAA
GGACCCTGTCATTCCCAGCATACAACTGTTTCCTGGTCTCAGAGAGCCAGAAGAGGTGCAAGGGAGCGTGGATATTGCCCTGTCTGTCAA
ATGTGACAATGAGAAGATGATCGTGGCTGTAGAAAAAGATTCTTTTCAGGCCAGTGGCTACTCGGGGATGGACGTCACCCTGTTGGATCC
TACCTGCAAGGCCAAGATGAATGGCACACACTTTGTTTTGGAGTCTCCTCTGAATGGCTGCGGTACTCGGCCCCGGTGGTCAGCCCTTGA
TGGTGTGGTCTACTATAACTCCATTGTGATACAGGTTCCAGCCCTTGGGGACAGTAGTGGTTGGCCAGATGGTTATGAAGATCTGGAGTC
AGGTGATAATGGATTTCCGGGAGATATGGATGAAGGAGATGCTTCCCTGTTCACCCGACCTGAAATCGTGGTGTTTAATTGCAGCCTTCA
GCAGGTGAGGAACCCCAGCAGCTTCCAGGAACAGCCCCACGGAAACATCACCTTCAACATGGAGCTATACAACACTGACCTCTTTTTGGT
GCCCTCCCAGGGCGTCTTCTCTGTGCCAGAGAATGGACACGTTTATGTTGAGGTATCTGTTACTAAGGCTGAACAAGAACTGGGATTTGC
CATCCAAACGTGCTTTATCTCTCCATATTCGAACCCTGATAGGATGTCTCATTACACCATTATTGAGAATATTTGTCCTAAAGATGAATC
TGTGAAATTCTACAGTCCCAAGAGAGTGCACTTTCCTATCCCGCAAGCTGACATGGATAAGAAGCGATTCAGCTTTGTCTTCAAGCCTGT
CTTCAACACCTCACTGCTCTTTCTACAGTGTGAGCTGACGCTGTGTACGAAGATGGAGAAGCACCCCCAGAAGTTGCCTAAGTGTGTGCC
TCCTGACGAAGCCTGCACCTCGCTGGACGCCTCGATAATCTGGGCCATGATGCAGAATAAGAAGACGTTCACTAAGCCCCTTGCTGTGAT
CCACCATGAAGCAGAATCTAAAGAAAAAGGTCCAAGCATGAAGGAACCAAATCCAATTTCTCCACCAATTTTCCATGGTCTGGACACCCT
AACCGTGATGGGCATTGCGTTTGCAGCCTTTGTGATCGGAGCACTCCTGACGGGGGCCTTGTGGTACATCTATTCTCACACAGGGGAGAC
AGCAGGAAGGCAGCAAGTCCCCACCTCCCCGCCAGCCTCGGAAAACAGCAGTGCTGCCCACAGCATCGGCAGCACGCAGAGCACGCCTTG
CTCCAGCAGCAGCACGGCCTAGCCCAACCCAGCCCAACCCGGCCCAACCCAGCCCAGCCCAGCTCAGCTCAGCTACTGCCAAGGGCAGGA
CCAATGGCTGAGCCTCGTGTCCAGACTCAGAGGGCTGGATTTTGGTTCCCTTGTAAAGACAGAGTGAATTTCAGTATAAAGATCACCCGT
TGTATTCACCCCACACCCAGGGCTAGTATAAACATGACCCTGGGCTTCTGTACCACACTAGAATTCATGTGAGAAAGCTAAAATGGTGGT
CTTCTCCACCAGCCCCTCACAGGCTTGGGGGTTTTCAATGTGAAACACATGCCAGTTTTTAAAATGCTGCTTTGTCCAGGTGAGAACATC
CATAATTTGGGGCCCTGAGTTTTACCCAGACTCAAGGAGTTGGTAAAGGGTTAATAGCCAGATAGTAGAACCAGTGAGGAGATGCGGCCA
AAGATTCTTTATATCTGAACCAAGATGTAAAACAAGAAATGCTTTGAGGCTTTCTAAGCGATCCTCCTGTCTAATTTGCACCTTTGTCTG
GATGCACACTTCTGACCTTGCTGCCACAACCTGTGGGGTCTGATGTGTCCCTTGATGGGTGCTGCCCTCAGGGACTGCACCCTGACAAGT
GTTAAGGCAACATTCCTTTCTTGTGCCCTGGGCCAAAACCAATGCTGATGACCTTATCAGCTTCCTGTTTCTTCCCATACTTGCATACAC
CACTGCAAAATGTCTTAATGCAAATTTTGTATTTCTTACAGGCCTACAGAAATTGAAAATGACCAAAATCAGGAACCACAGATTTGTGCC
CATTCCTAATATTTTGTTCTGCAAATTAATGTATAATTTGAGGTGAAATTCAGTTATAAAGTCAAGGACGAATTTGCACAGTGATATATT
TCTATGTGTATGCAAGTACAAGTATATAATATGTCACCTGGCACATTCATTTTCTCAGTTGAAGAAGAGAAAATTTGAAAATGTCCTTAT
GCTTTTAGAGTTGCAACTTAAGTATATTTGGTAGGGTGAGTGTTTCCACTCAAAATATGTCAACTTAAAAAAAAATAGGCCCTTTCATAA
AAACCAAACTGTAGCAAGATGCAAATGCATGGCAAATCCTGTCGGTCTCCAGTTGGTTATCTGAATAGTGTCACCAATTCCACCAAGACA
GTGCTGAGATTGGAAAAGGGCACTCATTTGGATTGCCTTACTTCTCTTGCCTTAAATATATCCCATATATTTAATATGTCAAAAAGGGCT

>In-frame_ENST00000370813_ENST00000525962_TCGA-85-8582-01A_PIGK_chr1_77587960_-_TGFBR3_chr1_92187701_length(amino acids)=842AA_start in transcript=13_stop in transcript=2541
MKPVNMAVTDSLSRAATVLATVLLLSFGSVAASHIEDQAEQFFRSGHTNNWAVLVTVENFLRVLTGRIPPSTPRSKRLLSDDRSNILIYM
TGHGGNGFLKFQDSEEITNIELADAFEQMWQKRRYNELLFIIDTCQGASMYERFYSPNIMALASSQVGEDSLSHQPDPAIGVHLMDRYTF
YVLEFLEEINPASQTNMNDLFQVCPKSLCVSTPGHRTDLFQRDPKNVLITDFFGSVRKVEITTETIKLQQDSEIMESSYKEDQMDEKLME
PLKYAEQLPVAQIIHQAPNSIGFGKESERSMTMTKSIRDDIPSTQGNLVKWALDNGYSPITSYTMAPVANRFHLRLENNAEEMGDEEVHT
IPPELRILLDPGALPALQNPPIRGGEGQNGGLPFPFPDISRRVWNEEGEDGLPRPKDPVIPSIQLFPGLREPEEVQGSVDIALSVKCDNE
KMIVAVEKDSFQASGYSGMDVTLLDPTCKAKMNGTHFVLESPLNGCGTRPRWSALDGVVYYNSIVIQVPALGDSSGWPDGYEDLESGDNG
FPGDMDEGDASLFTRPEIVVFNCSLQQVRNPSSFQEQPHGNITFNMELYNTDLFLVPSQGVFSVPENGHVYVEVSVTKAEQELGFAIQTC
FISPYSNPDRMSHYTIIENICPKDESVKFYSPKRVHFPIPQADMDKKRFSFVFKPVFNTSLLFLQCELTLCTKMEKHPQKLPKCVPPDEA
CTSLDASIIWAMMQNKKTFTKPLAVIHHEAESKEKGPSMKEPNPISPPIFHGLDTLTVMGIAFAAFVIGALLTGALWYIYSHTGETAGRQ

--------------------------------------------------------------

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Fusion Gene PPI Analysis for PIGK-TGFBR3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneTGFBR3chr1:77587960chr1:92187701ENST00000212355617737_751295.0852.0TGF-beta ligand
TgeneTGFBR3chr1:77587960chr1:92187701ENST00000370399718737_751295.0851.0TGF-beta ligand
TgeneTGFBR3chr1:77587960chr1:92187701ENST00000525962516737_751295.0852.0TGF-beta ligand


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for PIGK-TGFBR3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for PIGK-TGFBR3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneTGFBR3C1862932ANEURYSM, INTRACRANIAL BERRY, 1 (disorder)1ORPHANET