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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:PLCB2-MAPKBP1 (FusionGDB2 ID:65571)

Fusion Gene Summary for PLCB2-MAPKBP1

check button Fusion gene summary
Fusion gene informationFusion gene name: PLCB2-MAPKBP1
Fusion gene ID: 65571
HgeneTgene
Gene symbol

PLCB2

MAPKBP1

Gene ID

5330

23005

Gene namephospholipase C beta 2mitogen-activated protein kinase binding protein 1
SynonymsPLC-beta-2JNKBP-1|JNKBP1|NPHP20
Cytomap

15q15.1

15q15.1

Type of geneprotein-codingprotein-coding
Description1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2phosphoinositide phospholipase C-beta-2mitogen-activated protein kinase-binding protein 1JNK-binding protein 1
Modification date2020032020200313
UniProtAcc.

O60336

Ensembl transtripts involved in fusion geneENST00000260402, ENST00000557821, 
ENST00000456256, ENST00000543785, 
ENST00000221214, ENST00000457542, 
ENST00000260357, ENST00000456763, 
ENST00000514566, ENST00000507762, 
Fusion gene scores* DoF score5 X 5 X 3=754 X 5 X 3=60
# samples 55
** MAII scorelog2(5/75*10)=-0.584962500721156
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(5/60*10)=-0.263034405833794
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: PLCB2 [Title/Abstract] AND MAPKBP1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointPLCB2(40581473)-MAPKBP1(42092021), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across PLCB2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across MAPKBP1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4MESOTCGA-3H-AB3M-01APLCB2chr15

40581473

-MAPKBP1chr15

42092021

+


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Fusion Gene ORF analysis for PLCB2-MAPKBP1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000260402ENST00000221214PLCB2chr15

40581473

-MAPKBP1chr15

42092021

+
In-frameENST00000260402ENST00000457542PLCB2chr15

40581473

-MAPKBP1chr15

42092021

+
5CDS-intronENST00000260402ENST00000260357PLCB2chr15

40581473

-MAPKBP1chr15

42092021

+
5CDS-intronENST00000260402ENST00000456763PLCB2chr15

40581473

-MAPKBP1chr15

42092021

+
5CDS-intronENST00000260402ENST00000514566PLCB2chr15

40581473

-MAPKBP1chr15

42092021

+
5CDS-3UTRENST00000260402ENST00000507762PLCB2chr15

40581473

-MAPKBP1chr15

42092021

+
In-frameENST00000557821ENST00000221214PLCB2chr15

40581473

-MAPKBP1chr15

42092021

+
In-frameENST00000557821ENST00000457542PLCB2chr15

40581473

-MAPKBP1chr15

42092021

+
5CDS-intronENST00000557821ENST00000260357PLCB2chr15

40581473

-MAPKBP1chr15

42092021

+
5CDS-intronENST00000557821ENST00000456763PLCB2chr15

40581473

-MAPKBP1chr15

42092021

+
5CDS-intronENST00000557821ENST00000514566PLCB2chr15

40581473

-MAPKBP1chr15

42092021

+
5CDS-3UTRENST00000557821ENST00000507762PLCB2chr15

40581473

-MAPKBP1chr15

42092021

+
In-frameENST00000456256ENST00000221214PLCB2chr15

40581473

-MAPKBP1chr15

42092021

+
In-frameENST00000456256ENST00000457542PLCB2chr15

40581473

-MAPKBP1chr15

42092021

+
5CDS-intronENST00000456256ENST00000260357PLCB2chr15

40581473

-MAPKBP1chr15

42092021

+
5CDS-intronENST00000456256ENST00000456763PLCB2chr15

40581473

-MAPKBP1chr15

42092021

+
5CDS-intronENST00000456256ENST00000514566PLCB2chr15

40581473

-MAPKBP1chr15

42092021

+
5CDS-3UTRENST00000456256ENST00000507762PLCB2chr15

40581473

-MAPKBP1chr15

42092021

+
intron-3CDSENST00000543785ENST00000221214PLCB2chr15

40581473

-MAPKBP1chr15

42092021

+
intron-3CDSENST00000543785ENST00000457542PLCB2chr15

40581473

-MAPKBP1chr15

42092021

+
intron-intronENST00000543785ENST00000260357PLCB2chr15

40581473

-MAPKBP1chr15

42092021

+
intron-intronENST00000543785ENST00000456763PLCB2chr15

40581473

-MAPKBP1chr15

42092021

+
intron-intronENST00000543785ENST00000514566PLCB2chr15

40581473

-MAPKBP1chr15

42092021

+
intron-3UTRENST00000543785ENST00000507762PLCB2chr15

40581473

-MAPKBP1chr15

42092021

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000260402PLCB2chr1540581473-ENST00000221214MAPKBP1chr1542092021+10083360418176652494
ENST00000260402PLCB2chr1540581473-ENST00000457542MAPKBP1chr1542092021+10436360418180162611
ENST00000557821PLCB2chr1540581473-ENST00000221214MAPKBP1chr1542092021+998635079675682490
ENST00000557821PLCB2chr1540581473-ENST00000457542MAPKBP1chr1542092021+1033935079679192607
ENST00000456256PLCB2chr1540581473-ENST00000221214MAPKBP1chr1542092021+994134628475232479
ENST00000456256PLCB2chr1540581473-ENST00000457542MAPKBP1chr1542092021+1029434628478742596

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000260402ENST00000221214PLCB2chr1540581473-MAPKBP1chr1542092021+0.0037532790.99624676
ENST00000260402ENST00000457542PLCB2chr1540581473-MAPKBP1chr1542092021+0.0035414430.9964586
ENST00000557821ENST00000221214PLCB2chr1540581473-MAPKBP1chr1542092021+0.0034747550.9965252
ENST00000557821ENST00000457542PLCB2chr1540581473-MAPKBP1chr1542092021+0.0032766630.99672335
ENST00000456256ENST00000221214PLCB2chr1540581473-MAPKBP1chr1542092021+0.0032654790.99673444
ENST00000456256ENST00000457542PLCB2chr1540581473-MAPKBP1chr1542092021+0.0030850730.99691486

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Fusion Genomic Features for PLCB2-MAPKBP1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
PLCB2chr1540581472-MAPKBP1chr1542092020+0.0002821720.9997178
PLCB2chr1540581472-MAPKBP1chr1542092020+0.0002821720.9997178

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for PLCB2-MAPKBP1


check button Go to

FGviewer for the breakpoints of chr15:40581473-chr15:42092021

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.MAPKBP1

O60336

FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Negative regulator of NOD2 function. It down-regulates NOD2-induced processes such as activation of NF-kappa-B signaling, IL8 secretion and antibacterial response (PubMed:22700971). Involved in JNK signaling pathway (By similarity). {ECO:0000250|UniProtKB:Q6NS57, ECO:0000269|PubMed:22700971}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePLCB2chr15:40581473chr15:42092021ENST00000260402-3132500_5451118.01186.0Compositional biasNote=Glu-rich
HgenePLCB2chr15:40581473chr15:42092021ENST00000557821-3132500_5451114.01182.0Compositional biasNote=Glu-rich
HgenePLCB2chr15:40581473chr15:42092021ENST00000260402-3132312_4631118.01186.0DomainPI-PLC X-box
HgenePLCB2chr15:40581473chr15:42092021ENST00000260402-3132546_6621118.01186.0DomainPI-PLC Y-box
HgenePLCB2chr15:40581473chr15:42092021ENST00000260402-3132662_7901118.01186.0DomainC2
HgenePLCB2chr15:40581473chr15:42092021ENST00000557821-3132312_4631114.01182.0DomainPI-PLC X-box
HgenePLCB2chr15:40581473chr15:42092021ENST00000557821-3132546_6621114.01182.0DomainPI-PLC Y-box
HgenePLCB2chr15:40581473chr15:42092021ENST00000557821-3132662_7901114.01182.0DomainC2
TgeneMAPKBP1chr15:40581473chr15:42092021ENST000004567631321041_104738.01515.0Compositional biasNote=Poly-Glu
TgeneMAPKBP1chr15:40581473chr15:42092021ENST000004567631321114_111938.01515.0Compositional biasNote=Poly-Ser
TgeneMAPKBP1chr15:40581473chr15:42092021ENST000004567631321387_139038.01515.0Compositional biasNote=Poly-Pro
TgeneMAPKBP1chr15:40581473chr15:42092021ENST000004575421311041_104738.01509.0Compositional biasNote=Poly-Glu
TgeneMAPKBP1chr15:40581473chr15:42092021ENST000004575421311114_111938.01509.0Compositional biasNote=Poly-Ser
TgeneMAPKBP1chr15:40581473chr15:42092021ENST000004575421311387_139038.01509.0Compositional biasNote=Poly-Pro
TgeneMAPKBP1chr15:40581473chr15:42092021ENST000005145661301041_104738.01232.0Compositional biasNote=Poly-Glu
TgeneMAPKBP1chr15:40581473chr15:42092021ENST000005145661301114_111938.01232.0Compositional biasNote=Poly-Ser
TgeneMAPKBP1chr15:40581473chr15:42092021ENST000005145661301387_139038.01232.0Compositional biasNote=Poly-Pro
TgeneMAPKBP1chr15:40581473chr15:42092021ENST00000456763132132_17338.01515.0RepeatNote=WD 2
TgeneMAPKBP1chr15:40581473chr15:42092021ENST00000456763132175_21338.01515.0RepeatNote=WD 3
TgeneMAPKBP1chr15:40581473chr15:42092021ENST00000456763132276_31538.01515.0RepeatNote=WD 4
TgeneMAPKBP1chr15:40581473chr15:42092021ENST00000456763132342_38138.01515.0RepeatNote=WD 5
TgeneMAPKBP1chr15:40581473chr15:42092021ENST00000456763132387_43638.01515.0RepeatNote=WD 6
TgeneMAPKBP1chr15:40581473chr15:42092021ENST00000456763132477_51638.01515.0RepeatNote=WD 7
TgeneMAPKBP1chr15:40581473chr15:42092021ENST00000456763132519_56138.01515.0RepeatNote=WD 8
TgeneMAPKBP1chr15:40581473chr15:42092021ENST00000456763132565_60638.01515.0RepeatNote=WD 9
TgeneMAPKBP1chr15:40581473chr15:42092021ENST00000456763132614_65338.01515.0RepeatNote=WD 10
TgeneMAPKBP1chr15:40581473chr15:42092021ENST00000456763132659_69838.01515.0RepeatNote=WD 11
TgeneMAPKBP1chr15:40581473chr15:42092021ENST00000456763132701_74038.01515.0RepeatNote=WD 12
TgeneMAPKBP1chr15:40581473chr15:42092021ENST0000045676313288_12938.01515.0RepeatNote=WD 1
TgeneMAPKBP1chr15:40581473chr15:42092021ENST00000457542131132_17338.01509.0RepeatNote=WD 2
TgeneMAPKBP1chr15:40581473chr15:42092021ENST00000457542131175_21338.01509.0RepeatNote=WD 3
TgeneMAPKBP1chr15:40581473chr15:42092021ENST00000457542131276_31538.01509.0RepeatNote=WD 4
TgeneMAPKBP1chr15:40581473chr15:42092021ENST00000457542131342_38138.01509.0RepeatNote=WD 5
TgeneMAPKBP1chr15:40581473chr15:42092021ENST00000457542131387_43638.01509.0RepeatNote=WD 6
TgeneMAPKBP1chr15:40581473chr15:42092021ENST00000457542131477_51638.01509.0RepeatNote=WD 7
TgeneMAPKBP1chr15:40581473chr15:42092021ENST00000457542131519_56138.01509.0RepeatNote=WD 8
TgeneMAPKBP1chr15:40581473chr15:42092021ENST00000457542131565_60638.01509.0RepeatNote=WD 9
TgeneMAPKBP1chr15:40581473chr15:42092021ENST00000457542131614_65338.01509.0RepeatNote=WD 10
TgeneMAPKBP1chr15:40581473chr15:42092021ENST00000457542131659_69838.01509.0RepeatNote=WD 11
TgeneMAPKBP1chr15:40581473chr15:42092021ENST00000457542131701_74038.01509.0RepeatNote=WD 12
TgeneMAPKBP1chr15:40581473chr15:42092021ENST0000045754213188_12938.01509.0RepeatNote=WD 1
TgeneMAPKBP1chr15:40581473chr15:42092021ENST00000514566130132_17338.01232.0RepeatNote=WD 2
TgeneMAPKBP1chr15:40581473chr15:42092021ENST00000514566130175_21338.01232.0RepeatNote=WD 3
TgeneMAPKBP1chr15:40581473chr15:42092021ENST00000514566130276_31538.01232.0RepeatNote=WD 4
TgeneMAPKBP1chr15:40581473chr15:42092021ENST00000514566130342_38138.01232.0RepeatNote=WD 5
TgeneMAPKBP1chr15:40581473chr15:42092021ENST00000514566130387_43638.01232.0RepeatNote=WD 6
TgeneMAPKBP1chr15:40581473chr15:42092021ENST00000514566130477_51638.01232.0RepeatNote=WD 7
TgeneMAPKBP1chr15:40581473chr15:42092021ENST00000514566130519_56138.01232.0RepeatNote=WD 8
TgeneMAPKBP1chr15:40581473chr15:42092021ENST00000514566130565_60638.01232.0RepeatNote=WD 9
TgeneMAPKBP1chr15:40581473chr15:42092021ENST00000514566130614_65338.01232.0RepeatNote=WD 10
TgeneMAPKBP1chr15:40581473chr15:42092021ENST00000514566130659_69838.01232.0RepeatNote=WD 11
TgeneMAPKBP1chr15:40581473chr15:42092021ENST00000514566130701_74038.01232.0RepeatNote=WD 12
TgeneMAPKBP1chr15:40581473chr15:42092021ENST0000051456613088_12938.01232.0RepeatNote=WD 1

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePLCB2chr15:40581473chr15:42092021ENST00000260402-3132988_11471118.01186.0Coiled coilOntology_term=ECO:0000255
HgenePLCB2chr15:40581473chr15:42092021ENST00000557821-3132988_11471114.01182.0Coiled coilOntology_term=ECO:0000255


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Fusion Gene Sequence for PLCB2-MAPKBP1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000260402_ENST00000221214_TCGA-3H-AB3M-01A_PLCB2_chr15_40581473_-_MAPKBP1_chr15_42092021_length(transcript)=10083nt_BP=3604nt
ACAGGCCCCCATGGCAGGCAGGGCGGGTGGGAGGAGGGTGATTTACAAGGCAGATGGGCCTCTGGCTACAGCTCAGTCCTGCACTCAGCC
AGGGCCACCCCAGGGGCTATAAGAGCAACTAGATTTCTGGAGCAGCTCGGGGATGGGTGCCATTTGAGCCCAGCTTGGCTCCCCCTCCTG
GCTGGCCTCCTTCCTGCCCTTCTGCCTGCCTGTGTCTGCTGAGATTCTGCAAAGAGGAACGCTTGGCACCATGTCTCTGCTCAACCCTGT
CCTGCTGCCCCCCAAGGTGAAGGCCTATCTGAGCCAAGGGGAGCGCTTCATCAAATGGGATGATGAAACTACAGTTGCCTCTCCAGTTAT
CCTCCGTGTGGATCCTAAGGGCTACTACTTATACTGGACGTATCAAAGTAAGGAGATGGAGTTTCTGGATATCACCAGCATCCGGGATAC
TCGCTTTGGGAAGTTTGCCAAGATGCCCAAGAGCCAGAAGCTCCGGGACGTCTTCAACATGGACTTTCCTGATAACAGTTTCCTGCTGAA
GACACTCACGGTGGTGTCCGGCCCGGACATGGTGGACCTCACCTTCCACAACTTCGTCTCCTACAAGGAGAACGTGGGCAAGGCCTGGGC
TGAGGACGTACTGGCCCTAGTCAAACATCCGCTGACGGCCAACGCCTCCCGCAGCACCTTCCTGGACAAGATCCTTGTGAAGCTCAAGAT
GCAGCTCAACTCTGAAGGGAAGATTCCGGTGAAGAACTTTTTCCAGATGTTTCCTGCTGACCGCAAGCGGGTGGAAGCTGCTCTCAGTGC
CTGCCACCTCCCCAAAGGCAAAAATGACGCCATCAATCCTGAGGACTTCCCAGAACCTGTCTACAAGAGTTTCCTCATGAGCCTCTGTCC
TCGGCCAGAAATAGATGAGATCTTCACTTCTTACCATGCTAAGGCCAAACCCTACATGACGAAGGAGCACCTGACCAAATTCATCAACCA
GAAACAGCGGGACTCCCGGCTTAACTCCCTGCTGTTCCCGCCAGCACGGCCTGACCAGGTGCAGGGCCTCATCGACAAGTATGAGCCCAG
TGGCATCAATGCACAGAGGGGCCAGCTGTCACCTGAAGGCATGGTCTGGTTTCTCTGTGGGCCAGAGAACAGCGTGCTGGCCCAGGACAA
GCTGCTGCTCCACCACGACATGACGCAGCCACTCAATCATTACTTCATCAACTCGTCCCACAACACCTACCTGACAGCCGGCCAGTTCTC
AGGCCTCTCCTCGGCTGAGATGTACCGCCAGGTGCTGCTCTCTGGCTGCCGTTGCGTGGAGCTAGACTGCTGGAAGGGGAAACCCCCTGA
CGAGGAGCCCATTATCACCCATGGCTTCACCATGACCACAGACATCTTCTTCAAAGAAGCAATTGAGGCTATTGCAGAAAGCGCCTTTAA
GACCTCCCCCTATCCCATCATCCTGTCGTTTGAGAACCATGTGGACTCACCCCGCCAGCAGGCTAAGATGGCTGAGTATTGCCGGACGAT
CTTTGGGGATATGCTGCTCACAGAGCCCCTGGAAAAGTTCCCACTAAAACCAGGTGTCCCCCTGCCCAGCCCTGAGGATCTCAGGGGCAA
GATCCTCATCAAGAACAAGAAGAACCAGTTTTCTGGCCCCACCTCCTCCAGTAAGGATACTGGTGGGGAGGCTGAGGGCAGCAGCCCACC
CAGTGCCCCTGCAGGTGAGGGCACAGTGTGGGCTGGCGAGGAAGGGACTGAGCTGGAGGAGGAGGAGGTGGAAGAGGAAGAGGAGGAGGA
GTCAGGAAACCTGGATGAAGAAGAGATTAAGAAGATGCAGTCGGATGAGGGCACAGCGGGCCTGGAAGTGACGGCTTATGAGGAGATGTC
CAGCCTAGTCAATTACATCCAGCCCACCAAGTTCGTCTCCTTTGAGTTCTCTGCCCAAAAGAACCGAAGTTATGTCATCTCGTCCTTCAC
AGAGCTCAAGGCATATGACCTGCTCTCCAAGGCCTCGGTGCAGTTTGTGGACTACAACAAGCGCCAGATGAGCCGCATTTACCCCAAGGG
AACCCGCATGGACTCCTCCAACTACATGCCCCAGATGTTCTGGAATGCTGGATGCCAGATGGTTGCCCTCAACTTCCAGACGATGGACTT
GCCCATGCAGCAGAACATGGCAGTATTTGAGTTCAACGGGCAGAGCGGCTACCTCCTCAAGCATGAGTTCATGCGCCGGCCGGACAAGCA
GTTCAACCCCTTCTCAGTGGACCGCATCGACGTGGTGGTGGCCACCACCCTTTCCATTACGGTGATCTCTGGGCAGTTCCTGTCAGAACG
CAGCGTGCGCACCTATGTAGAAGTGGAGCTGTTTGGCCTTCCTGGGGACCCCAAGAGGCGCTATCGAACTAAGCTGTCACCCAGTACTAA
CTCCATCAATCCTGTCTGGAAGGAGGAGCCCTTTGTCTTTGAGAAGATCTTGATGCCTGAGCTGGCCTCCCTCAGAGTGGCTGTGATGGA
GGAAGGCAACAAGTTTCTTGGACACCGCATCATCCCCATCAATGCCCTAAATTCTGGGTACCACCACCTGTGCCTGCACAGTGAGAGCAA
CATGCCCCTCACCATGCCTGCGCTCTTCATCTTCCTGGAGATGAAGGACTACATACCTGGTGCTTGGGCAGATCTCACTGTGGCCCTCGC
CAACCCCATTAAGTTCTTCAGTGCCCATGACACGAAGTCTGTGAAGCTCAAGGAGGCCATGGGAGGTCTGCCTGAGAAGCCCTTCCCACT
GGCGAGTCCAGTTGCCAGCCAGGTCAATGGGGCGTTGGCCCCAACGAGCAATGGGTCACCAGCAGCCAGGGCCGGGGCCAGGGAAGAGGC
TATGAAAGAAGCTGCGGAGCCGCGGACCGCCAGCCTGGAGGAGCTCCGGGAGCTAAAGGGCGTGGTGAAGCTGCAGCGGCGGCACGAGAA
GGAGCTGCGAGAGTTGGAGCGGCGCGGAGCGCGGCGCTGGGAGGAGCTGCTGCAGCGGGGCGCGGCGCAGCTGGCGGAGCTCGGGCCACC
GGGCGTGGGGGGCGTCGGGGCCTGCAAGCTCGGTCCCGGCAAGGGCTCTCGCAAGAAGAGGAGCCTGCCCCGCGAGGAGAGCGCCGGAGC
CGCGCCGGGCGAGGGCCCTGAGGGCGTGGACGGGCGCGTGCGGGAGCTGAAAGACAGGCTGGAGCTGGAGCTGCTGCGGCAGGGCGAGGA
GCAGTACGAGTGCGTTCTGAAGCGCAAGGAGCAGCACGTGGCCGAGCAAATCTCCAAAATGATGGAGCTGGCCAGAGAGAAACAGGCGGC
AGAGCTGAAGGCCCTGAAGGAGACGTCGGAGAACGACACCAAAGAGATGAAGAAAAAGCTGGAGACAAAGAGACTGGAGCGGATCCAGGG
CATGACCAAAGTCACCACAGACAAGATGGCCCAGGAGAGGTTGAAGAGAGAGATTAACAACTCCCACATCCAGGAAGTAGTGCAGGTGAT
CAAGCAGATGACGGAGAACTTGGAGAGGCACCAGGAGAAGCTGGAGGAGAAGCAGGCGGCTTGCCTGGAACAGATACGGGAGATGGAAAA
GCAGGTGACCTTGGAGAAGGTGCTGGGAATTACAGTGTCTGGAGGCAGAGGACTTGCCTGTGACCCCCGATCAGGTTTAGTTGCTTACCC
AGCAGGGTGTGTGGTTGTGTTGTTCAATCCCCGGAAACACAAACAGCACCACATCCTCAACAGTTCCAGGAAAACCATCACTGCCCTTGC
CTTCTCCCCTGATGGCAAGTACTTGGTCACTGGAGAGAGTGGGCACATGCCTGCCGTGCGGGTTTGGGACGTGGCAGAGCACAGCCAGGT
GGCCGAGCTGCAGGAGCACAAGTATGGTGTGGCTTGTGTGGCCTTCTCTCCTAGCGCCAAGTACATTGTCTCTGTGGGCTACCAGCATGA
CATGATCGTCAACGTGTGGGCCTGGAAGAAAAACATTGTGGTGGCCTCCAACAAGGTGTCCAGTCGGGTGACAGCAGTGTCCTTCTCTGA
GGATTGCAGCTACTTTGTCACTGCAGGCAACCGACACATCAAATTCTGGTATCTCGATGACAGCAAGACCTCAAAGGTGAATGCCACTGT
GCCCTTGCTGGGCCGCTCAGGGCTGCTGGGAGAGCTACGGAACAACCTATTCACTGATGTGGCCTGTGGCAGAGGAAAAAAGGCGGACAG
TACCTTCTGCATCACGTCCTCAGGGCTGCTGTGCGAGTTCAGTGATCGAAGGCTTTTGGACAAGTGGGTGGAGCTGAGGGTCTACCCCGA
GGTGAAGGATAGTAACCAGGCCTGCCTGCCCCCCAGTTCCTTTATTACCTGCTCCTCAGACAACACCATCCGCCTGTGGAACACAGAGAG
CTCCGGGGTGCATGGCTCCACCCTCCACCGAAACATCCTCAGCAGTGACCTCATTAAAATCATCTATGTGGATGGGAACACCCAGGCCCT
GCTGGACACAGAGCTGCCTGGAGGAGACAAAGCTGATGCATCCCTGTTGGATCCCCGCGTGGGCATCCGCTCGGTGTGTGTCAGCCCCAA
TGGACAGCATCTAGCATCAGGGGACCGTATGGGCACACTTAGGGTGCACGAACTTCAGTCCCTGAGTGAGATGCTGAAGGTGGAGGCCCA
TGACTCTGAGATTCTGTGCCTGGAGTATTCTAAGCCAGACACAGGTCTGAAACTGCTAGCATCGGCGAGCCGGGACCGGCTGATCCATGT
GCTGGATGCCGGGCGGGAGTACAGCCTACAGCAGACGCTGGACGAACACTCATCCTCCATCACTGCTGTTAAGTTTGCAGCCAGTGATGG
GCAAGTCCGCATGATCAGCTGTGGAGCAGACAAGAGCATCTACTTCCGCACTGCGCAGAAGTCTGGAGATGGAGTGCAGTTCACACGGAC
ACACCACGTGGTGCGGAAGACGACCCTCTATGACATGGATGTGGAGCCCAGCTGGAAGTACACGGCTATCGGCTGCCAGGACCGAAATAT
TCGGATATTTAACATCAGCAGTGGAAAGCAGAAGAAGCTGTTTAAAGGGTCACAGGGTGAGGACGGCACACTCATTAAGGTGCAGACAGA
CCCCTCAGGGATCTACATTGCCACCAGCTGTTCTGACAAGAATCTCTCCATTTTTGACTTCTCCTCAGGCGAGTGCGTGGCCACCATGTT
TGGCCACTCAGAGATTGTCACTGGCATGAAATTTAGTAATGATTGTAAACATCTCATCTCTGTGTCTGGGGACAGCTGCATATTTGTGTG
GCGCCTGAGCTCTGAGATGACCATCAGCATGAGGCAGCGTCTGGCCGAGTTGCGCCAGCGTCAGCGGGGCGGCAAGCAGCAAGGACCATC
CTCTCCCCAAAGGGCTTCTGGACCCAACCGGCACCAGGCCCCATCAATGCTGTCTCCTGGACCGGCTCTCTCATCAGACAGTGACAAGGA
GGGAGAAGATGAGGGGACTGAAGAAGAACTTCCAGCACTGCCCGTCCTTGCCAAGAGTACCAAGAAGGCACTGGCCTCGGTCCCCAGCCC
AGCTTTGCCCCGAAGCCTGTCCCACTGGGAGATGAGTCGGGCACAGGAGTCCGTGGGGTTCCTGGACCCAGCTCCTGCAGCCAACCCAGG
ACCCAGAAGAAGAGGGCGCTGGGTTCAGCCAGGTGTGGAACTGAGCGTTAGATCCATGCTGGATCTGCGGCAGCTGGAAACACTGGCCCC
AAGCCTGCAGGACCCTAGCCAGGACTCGCTGGCCATCATCCCATCTGGTCCCAGGAAGCATGGGCAGGAGGCCCTTGAGACTTCACTCAC
TAGCCAGAATGAAAAGCCCCCTCGGCCTCAGGCTTCCCAACCTTGTTCCTATCCCCATATTATCCGATTATTGTCACAAGAGGAAGGGGT
CTTTGCCCAAGATCTGGAACCTGCACCCATTGAAGATGGTATTGTCTACCCGGAGCCGAGTGACAACCCCACCATGGATACCAGTGAGTT
CCAAGTGCAGGCTCCAGCCCGGGGAACTCTGGGAAGAGTGTACCCAGGCAGCAGGAGCTCAGAAAAGCACAGCCCTGACAGTGCCTGCTC
TGTGGATTACAGCAGCAGCTGCCTTTCCAGCCCGGAGCACCCCACTGAAGACTCTGAGAGCACGGAGCCCCTCAGTGTGGATGGCATCTC
CTCAGACCTTGAAGAGCCAGCTGAGGGTGATGAAGAAGAGGAAGAAGAGGAGGGAGGCATGGGCCCCTATGGGCTACAGGAGGGCAGCCC
CCAGACTCCAGACCAGGAGCAGTTTCTAAAACAGCACTTTGAGACTCTGGCCAGTGGAGCTGCTCCAGGGGCCCCAGTGCAGGTCCCAGA
GAGGTCAGAGTCTCGGAGTATCTCTTCACGATTCCTGTTGCAAGTACAGACCCGCCCACTCAGGGAACCATCCCCATCCTCCTCAAGCCT
GGCACTGATGTCGAGACCAGCCCAGGTGCCACAGGCATCTGGTGAGCAGCCGAGAGGCAATGGTGCCAATCCCCCTGGAGCACCCCCGGA
GGTGGAACCGTCCTCTGGCAACCCCAGCCCCCAGCAGGCAGCCTCTGTGCTGTTGCCACGATGCCGTCTCAACCCTGACAGCAGCTGGGC
TCCCAAGAGAGTGGCCACAGCCAGCCCCTTTTCTGGACTCCAGAAGGCCCAGTCTGTGCACAGTCTGGTGCCACAGGAAAGACATGAGGC
CAGTCTGCAGGCCCCTTCACCAGGCGCACTGCTGTCTCGGGAGATCGAAGCTCAGGATGGTCTGGGCTCCCTGCCCCCAGCTGATGGCCG
TCCGTCTCGGCCTCACTCCTATCAGAACCCCACCACCAGTTCCATGGCCAAGATATCCCGCAGTATCTCTGTTGGGGAGAACCTGGGCCT
GGTGGCTGAACCTCAAGCTCATGCCCCCATCCGAGTCTCACCACTCAGCAAGCTGGCCCTGCCCAGCCGGGCTCACCTGGTCCTGGACAT
CCCCAAACCACTGCCTGACCGTCCTACCCTGGCTGCATTCTCTCCTGTCACCAAAGGCCGGGCCCCTGGCGAGGCAGAAAAGCCTGGCTT
CCCGGTGGGCCTAGGAAAAGCTCACAGTACAACTGAGAGATGGGCCTGTTTGGGGGAGGGCACCACTCCCAAGCCTAGGACAGAGTGCCA
GGCTCATCCTGGGCCCAGCAGCCCCTGTGCCCAGCAACTGCCAGTCAGCAGCCTCTTCCAAGGCCCTGAAAACTTGCAGCCCCCACCCCC
TGAGAAGACTCCCAACCCCATGGAATGCACCAAGCCAGGGGCAGCCCTGAGCCAGGACTCAGAGCCAGCGGTGAGCCTGGAGCAGTGTGA
GCAGCTGGTGGCAGAGCTCCGCGGCAGCGTGCGCCAGGCAGTGCGGCTCTACCACTCGGTGGCTGGCTGCAAGATGCCCTCAGCAGAGCA
AAGTCGGATTGCCCAGCTCCTCAGAGACACCTTCTCTTCAGTGCGACAGGAGCTGGAAGCTGTGGCTGGGGCAGTGCTGTCCAGCCCAGG
CAGCAGCCCTGGGGCTGTGGGAGCCGAGCAGACACAGGCCCTGCTGGAGCAATACTCAGAACTGTTGCTTCGAGCCGTGGAACGGCGTAT
GGAACGCAAACTCTGAGTTCTGGAAGCCTGTCCCAAGTGAATGAATGCTCCAGCGATTCCAAACTGCAGCCCCTCTGCCCCTCACCAAAA
CCTGCGGGGCTGCTTGGAGTGGAAAGCAGGGAGCAGTGTTCAGAGGCAAAGCAGCCTTCCCAGCCGCTCCTCGTGGGGGGCCTGTATTTA
TTAATTTATTTCCCTGACTGTTGCCTCACTTCCTTGGAACTCCTGCCTCCACAGCCCCTCCAGTGGCAGGGACAGGTCTTGGGTCTTTGT
CATCTTGGTGCTGTGAGAGGTAGGAGGGCAGCCTGCCCCATCTAGGAATCTGGGAAGGGCTGGCCCTCTCTTAGAAGCCATTTGAAATTA
CTGCAGGGATTAGCTCCCTGTGGTGGAGCATACACAGGGTACTCTGGGGTCGAGGTGAGAGGTGATGTGGTATTCAGTGCCCGTCAGCCA
ACTGTGGGCCTTCACCTCTACCTGCACTTCCCCTCTCACACCAGCTGCACTCCCGTGGCTGCCAGAGCAGGGTGGTTTTCCCCAATACCT
GGAGCTCAGAAAGGCAGAGCCATCTGGCCCTCCAGGGTGTCCCCAGCCATCAGGAGACTTGAGTTGGTATTTGGACCTGAGCCCGCACAT
TCCACTCCCATTCTCCCTCCAAGAGGGGCCCAGCATTGTATTTCCCTGTGACCCCTTACTCTCCTGGCCAGAACTTGAGCCAGCTGTGGG
ATGTTGCTGCAGGACAGTAAGCCCTCACCTGGGCAAACATGAAGCTCTGGCCTCCTTTCCTCAGCCCCTTGTTCTTCCCTGTCCTCCACC
CTGGACCCCAGCCGGCTGCTGGAGCCCAGAGGCCACCTTCTCCCTGCATCCTGAATGATGCTTAGTCAGAAGCCTGTGTTGGAACATCCC
TCGTTTACGGGGCGCTGGCCTACCTCCTGAGGACCTCAGCCACAGATGAGATCACACGCATGCACGTGCACACATGTACACACACACACC
TACCTGCACAGCACGCTGTTGAGTGTTGGTTGCTAGAGTATCTGGCTGGCTGCTGTGTGCCTGGTTTCCTCACATCCTGCCTCAGCTTCA
CCACCCTGGCTTATGTGGAACACCTATCAGGGAGCAGAAAAGGGGTGCAGTACACTAAGTGAACCCAGATTCTGGATTCTTGGTGTCCAC
AGCCTAGCTGATACGAGATAGCCCATAGGACACCTGGTTTAGGTAGAAGGAGCCTCCTCAAAGGCAGTGCTGGGCACCCACGGGTGTGCT
GGATACTGGAGTTTGAGAGGAGGGAGGTGCTGGGGCCAAAGGAGACACTAGAAAAGTGGTAGATGGGACAGGTAAGTGGCAGAGGTGAGG
GGATAAGTTAGAATGTAAAAGGGCAGTAATTAGGGGTGAGGGAAAGGAGATAGGGGACCCTAGGAGGTAGAGTGGGACCATGTCGTGAGG
CAGTTGAAGAGTTGAGGAAAGGTTTTTCTGGGCCCTACTGCTCCCCTCTGCTGCAGGTAAGTCAGAGCAGCTTTACCACAGCTTCAGGCC
ACGAGAGCCCCTTCACCCGCCCTGCTGCGCCATAGGCAGAGGCTTATAAAGAAATGGGTTCTGGGCCAGGTGTGGTGGCTCAAGCCTGTA
ATCCCAGCACTTTGGGAGGCCGAGGCGGGTGGATCACCTGAGGTTAGGAGTTCGAGATCAGCCTGGCCAACATGGTGAAACCCTGTCTAC
TAAAAATAAAAAAATTAGCTGGGCGTGGTGGTGGGCGCCTGTAATCCCAGCTACTCGGGAGGTTTAGGCAGGAGAATCGCTTGAACCCTG
GAGGTGGAGGTGGAGGTTGCAGTGAGCCGAGATCGCGCCATTGCACTCCAACCTAGGTGACAAAGCTACACGCCATCTCAAAAAAAAAAA
AGAAAAAGGGTTACAAAAGGTTCCCAGCTCCGGGGCATCAGCCTGAGTGCGCTTGAGCTGCTCCAAACCTGGCCCTTCCCCACTCCTCTA
GCATCGCCACCCGCATGGCCCTGGAACTCCCGCGGCGGCGGGGGCGGGCCCGTGCCTGCTGTGCCCCGACTTCCCACACCAGCCGCGCCC
ACCGCAGGTGGGACTCAGGTTCGCCCTCTGGGCCAGGTCCTTCACGAGGAGGGAGCTACCCTTCGCCAGAAGTTTGTGAGAATGTGGCCG
CCCTTTTCCTGCCCTCTGCCCCATGTGGGTGGGGGGCCTCGTGGCCCGGCCGGCGCCCCGTCCCCTTCTGCATGTCTGAGGCCACCGGCA
ACCGCCGCCCCACTCCAGATTTGCCCCCGCCTTGTTTTGAAAGCCCCTTATTTATAACTTTTATACTTTGTGCAGGTCGCGGCGCTTCCT
GCCTCATCCTCGGCTGCATGGGGCGGGGGCGCTGTTTTTAACGTGCCCGTTTGTACTGATGTATGAACTTGTCAATAAACACAATTGTTT

>In-frame_ENST00000260402_ENST00000221214_TCGA-3H-AB3M-01A_PLCB2_chr15_40581473_-_MAPKBP1_chr15_42092021_length(amino acids)=2494AA_start in transcript=181_stop in transcript=7665
MASFLPFCLPVSAEILQRGTLGTMSLLNPVLLPPKVKAYLSQGERFIKWDDETTVASPVILRVDPKGYYLYWTYQSKEMEFLDITSIRDT
RFGKFAKMPKSQKLRDVFNMDFPDNSFLLKTLTVVSGPDMVDLTFHNFVSYKENVGKAWAEDVLALVKHPLTANASRSTFLDKILVKLKM
QLNSEGKIPVKNFFQMFPADRKRVEAALSACHLPKGKNDAINPEDFPEPVYKSFLMSLCPRPEIDEIFTSYHAKAKPYMTKEHLTKFINQ
KQRDSRLNSLLFPPARPDQVQGLIDKYEPSGINAQRGQLSPEGMVWFLCGPENSVLAQDKLLLHHDMTQPLNHYFINSSHNTYLTAGQFS
GLSSAEMYRQVLLSGCRCVELDCWKGKPPDEEPIITHGFTMTTDIFFKEAIEAIAESAFKTSPYPIILSFENHVDSPRQQAKMAEYCRTI
FGDMLLTEPLEKFPLKPGVPLPSPEDLRGKILIKNKKNQFSGPTSSSKDTGGEAEGSSPPSAPAGEGTVWAGEEGTELEEEEVEEEEEEE
SGNLDEEEIKKMQSDEGTAGLEVTAYEEMSSLVNYIQPTKFVSFEFSAQKNRSYVISSFTELKAYDLLSKASVQFVDYNKRQMSRIYPKG
TRMDSSNYMPQMFWNAGCQMVALNFQTMDLPMQQNMAVFEFNGQSGYLLKHEFMRRPDKQFNPFSVDRIDVVVATTLSITVISGQFLSER
SVRTYVEVELFGLPGDPKRRYRTKLSPSTNSINPVWKEEPFVFEKILMPELASLRVAVMEEGNKFLGHRIIPINALNSGYHHLCLHSESN
MPLTMPALFIFLEMKDYIPGAWADLTVALANPIKFFSAHDTKSVKLKEAMGGLPEKPFPLASPVASQVNGALAPTSNGSPAARAGAREEA
MKEAAEPRTASLEELRELKGVVKLQRRHEKELRELERRGARRWEELLQRGAAQLAELGPPGVGGVGACKLGPGKGSRKKRSLPREESAGA
APGEGPEGVDGRVRELKDRLELELLRQGEEQYECVLKRKEQHVAEQISKMMELAREKQAAELKALKETSENDTKEMKKKLETKRLERIQG
MTKVTTDKMAQERLKREINNSHIQEVVQVIKQMTENLERHQEKLEEKQAACLEQIREMEKQVTLEKVLGITVSGGRGLACDPRSGLVAYP
AGCVVVLFNPRKHKQHHILNSSRKTITALAFSPDGKYLVTGESGHMPAVRVWDVAEHSQVAELQEHKYGVACVAFSPSAKYIVSVGYQHD
MIVNVWAWKKNIVVASNKVSSRVTAVSFSEDCSYFVTAGNRHIKFWYLDDSKTSKVNATVPLLGRSGLLGELRNNLFTDVACGRGKKADS
TFCITSSGLLCEFSDRRLLDKWVELRVYPEVKDSNQACLPPSSFITCSSDNTIRLWNTESSGVHGSTLHRNILSSDLIKIIYVDGNTQAL
LDTELPGGDKADASLLDPRVGIRSVCVSPNGQHLASGDRMGTLRVHELQSLSEMLKVEAHDSEILCLEYSKPDTGLKLLASASRDRLIHV
LDAGREYSLQQTLDEHSSSITAVKFAASDGQVRMISCGADKSIYFRTAQKSGDGVQFTRTHHVVRKTTLYDMDVEPSWKYTAIGCQDRNI
RIFNISSGKQKKLFKGSQGEDGTLIKVQTDPSGIYIATSCSDKNLSIFDFSSGECVATMFGHSEIVTGMKFSNDCKHLISVSGDSCIFVW
RLSSEMTISMRQRLAELRQRQRGGKQQGPSSPQRASGPNRHQAPSMLSPGPALSSDSDKEGEDEGTEEELPALPVLAKSTKKALASVPSP
ALPRSLSHWEMSRAQESVGFLDPAPAANPGPRRRGRWVQPGVELSVRSMLDLRQLETLAPSLQDPSQDSLAIIPSGPRKHGQEALETSLT
SQNEKPPRPQASQPCSYPHIIRLLSQEEGVFAQDLEPAPIEDGIVYPEPSDNPTMDTSEFQVQAPARGTLGRVYPGSRSSEKHSPDSACS
VDYSSSCLSSPEHPTEDSESTEPLSVDGISSDLEEPAEGDEEEEEEEGGMGPYGLQEGSPQTPDQEQFLKQHFETLASGAAPGAPVQVPE
RSESRSISSRFLLQVQTRPLREPSPSSSSLALMSRPAQVPQASGEQPRGNGANPPGAPPEVEPSSGNPSPQQAASVLLPRCRLNPDSSWA
PKRVATASPFSGLQKAQSVHSLVPQERHEASLQAPSPGALLSREIEAQDGLGSLPPADGRPSRPHSYQNPTTSSMAKISRSISVGENLGL
VAEPQAHAPIRVSPLSKLALPSRAHLVLDIPKPLPDRPTLAAFSPVTKGRAPGEAEKPGFPVGLGKAHSTTERWACLGEGTTPKPRTECQ
AHPGPSSPCAQQLPVSSLFQGPENLQPPPPEKTPNPMECTKPGAALSQDSEPAVSLEQCEQLVAELRGSVRQAVRLYHSVAGCKMPSAEQ

--------------------------------------------------------------
>In-frame_ENST00000260402_ENST00000457542_TCGA-3H-AB3M-01A_PLCB2_chr15_40581473_-_MAPKBP1_chr15_42092021_length(transcript)=10436nt_BP=3604nt
ACAGGCCCCCATGGCAGGCAGGGCGGGTGGGAGGAGGGTGATTTACAAGGCAGATGGGCCTCTGGCTACAGCTCAGTCCTGCACTCAGCC
AGGGCCACCCCAGGGGCTATAAGAGCAACTAGATTTCTGGAGCAGCTCGGGGATGGGTGCCATTTGAGCCCAGCTTGGCTCCCCCTCCTG
GCTGGCCTCCTTCCTGCCCTTCTGCCTGCCTGTGTCTGCTGAGATTCTGCAAAGAGGAACGCTTGGCACCATGTCTCTGCTCAACCCTGT
CCTGCTGCCCCCCAAGGTGAAGGCCTATCTGAGCCAAGGGGAGCGCTTCATCAAATGGGATGATGAAACTACAGTTGCCTCTCCAGTTAT
CCTCCGTGTGGATCCTAAGGGCTACTACTTATACTGGACGTATCAAAGTAAGGAGATGGAGTTTCTGGATATCACCAGCATCCGGGATAC
TCGCTTTGGGAAGTTTGCCAAGATGCCCAAGAGCCAGAAGCTCCGGGACGTCTTCAACATGGACTTTCCTGATAACAGTTTCCTGCTGAA
GACACTCACGGTGGTGTCCGGCCCGGACATGGTGGACCTCACCTTCCACAACTTCGTCTCCTACAAGGAGAACGTGGGCAAGGCCTGGGC
TGAGGACGTACTGGCCCTAGTCAAACATCCGCTGACGGCCAACGCCTCCCGCAGCACCTTCCTGGACAAGATCCTTGTGAAGCTCAAGAT
GCAGCTCAACTCTGAAGGGAAGATTCCGGTGAAGAACTTTTTCCAGATGTTTCCTGCTGACCGCAAGCGGGTGGAAGCTGCTCTCAGTGC
CTGCCACCTCCCCAAAGGCAAAAATGACGCCATCAATCCTGAGGACTTCCCAGAACCTGTCTACAAGAGTTTCCTCATGAGCCTCTGTCC
TCGGCCAGAAATAGATGAGATCTTCACTTCTTACCATGCTAAGGCCAAACCCTACATGACGAAGGAGCACCTGACCAAATTCATCAACCA
GAAACAGCGGGACTCCCGGCTTAACTCCCTGCTGTTCCCGCCAGCACGGCCTGACCAGGTGCAGGGCCTCATCGACAAGTATGAGCCCAG
TGGCATCAATGCACAGAGGGGCCAGCTGTCACCTGAAGGCATGGTCTGGTTTCTCTGTGGGCCAGAGAACAGCGTGCTGGCCCAGGACAA
GCTGCTGCTCCACCACGACATGACGCAGCCACTCAATCATTACTTCATCAACTCGTCCCACAACACCTACCTGACAGCCGGCCAGTTCTC
AGGCCTCTCCTCGGCTGAGATGTACCGCCAGGTGCTGCTCTCTGGCTGCCGTTGCGTGGAGCTAGACTGCTGGAAGGGGAAACCCCCTGA
CGAGGAGCCCATTATCACCCATGGCTTCACCATGACCACAGACATCTTCTTCAAAGAAGCAATTGAGGCTATTGCAGAAAGCGCCTTTAA
GACCTCCCCCTATCCCATCATCCTGTCGTTTGAGAACCATGTGGACTCACCCCGCCAGCAGGCTAAGATGGCTGAGTATTGCCGGACGAT
CTTTGGGGATATGCTGCTCACAGAGCCCCTGGAAAAGTTCCCACTAAAACCAGGTGTCCCCCTGCCCAGCCCTGAGGATCTCAGGGGCAA
GATCCTCATCAAGAACAAGAAGAACCAGTTTTCTGGCCCCACCTCCTCCAGTAAGGATACTGGTGGGGAGGCTGAGGGCAGCAGCCCACC
CAGTGCCCCTGCAGGTGAGGGCACAGTGTGGGCTGGCGAGGAAGGGACTGAGCTGGAGGAGGAGGAGGTGGAAGAGGAAGAGGAGGAGGA
GTCAGGAAACCTGGATGAAGAAGAGATTAAGAAGATGCAGTCGGATGAGGGCACAGCGGGCCTGGAAGTGACGGCTTATGAGGAGATGTC
CAGCCTAGTCAATTACATCCAGCCCACCAAGTTCGTCTCCTTTGAGTTCTCTGCCCAAAAGAACCGAAGTTATGTCATCTCGTCCTTCAC
AGAGCTCAAGGCATATGACCTGCTCTCCAAGGCCTCGGTGCAGTTTGTGGACTACAACAAGCGCCAGATGAGCCGCATTTACCCCAAGGG
AACCCGCATGGACTCCTCCAACTACATGCCCCAGATGTTCTGGAATGCTGGATGCCAGATGGTTGCCCTCAACTTCCAGACGATGGACTT
GCCCATGCAGCAGAACATGGCAGTATTTGAGTTCAACGGGCAGAGCGGCTACCTCCTCAAGCATGAGTTCATGCGCCGGCCGGACAAGCA
GTTCAACCCCTTCTCAGTGGACCGCATCGACGTGGTGGTGGCCACCACCCTTTCCATTACGGTGATCTCTGGGCAGTTCCTGTCAGAACG
CAGCGTGCGCACCTATGTAGAAGTGGAGCTGTTTGGCCTTCCTGGGGACCCCAAGAGGCGCTATCGAACTAAGCTGTCACCCAGTACTAA
CTCCATCAATCCTGTCTGGAAGGAGGAGCCCTTTGTCTTTGAGAAGATCTTGATGCCTGAGCTGGCCTCCCTCAGAGTGGCTGTGATGGA
GGAAGGCAACAAGTTTCTTGGACACCGCATCATCCCCATCAATGCCCTAAATTCTGGGTACCACCACCTGTGCCTGCACAGTGAGAGCAA
CATGCCCCTCACCATGCCTGCGCTCTTCATCTTCCTGGAGATGAAGGACTACATACCTGGTGCTTGGGCAGATCTCACTGTGGCCCTCGC
CAACCCCATTAAGTTCTTCAGTGCCCATGACACGAAGTCTGTGAAGCTCAAGGAGGCCATGGGAGGTCTGCCTGAGAAGCCCTTCCCACT
GGCGAGTCCAGTTGCCAGCCAGGTCAATGGGGCGTTGGCCCCAACGAGCAATGGGTCACCAGCAGCCAGGGCCGGGGCCAGGGAAGAGGC
TATGAAAGAAGCTGCGGAGCCGCGGACCGCCAGCCTGGAGGAGCTCCGGGAGCTAAAGGGCGTGGTGAAGCTGCAGCGGCGGCACGAGAA
GGAGCTGCGAGAGTTGGAGCGGCGCGGAGCGCGGCGCTGGGAGGAGCTGCTGCAGCGGGGCGCGGCGCAGCTGGCGGAGCTCGGGCCACC
GGGCGTGGGGGGCGTCGGGGCCTGCAAGCTCGGTCCCGGCAAGGGCTCTCGCAAGAAGAGGAGCCTGCCCCGCGAGGAGAGCGCCGGAGC
CGCGCCGGGCGAGGGCCCTGAGGGCGTGGACGGGCGCGTGCGGGAGCTGAAAGACAGGCTGGAGCTGGAGCTGCTGCGGCAGGGCGAGGA
GCAGTACGAGTGCGTTCTGAAGCGCAAGGAGCAGCACGTGGCCGAGCAAATCTCCAAAATGATGGAGCTGGCCAGAGAGAAACAGGCGGC
AGAGCTGAAGGCCCTGAAGGAGACGTCGGAGAACGACACCAAAGAGATGAAGAAAAAGCTGGAGACAAAGAGACTGGAGCGGATCCAGGG
CATGACCAAAGTCACCACAGACAAGATGGCCCAGGAGAGGTTGAAGAGAGAGATTAACAACTCCCACATCCAGGAAGTAGTGCAGGTGAT
CAAGCAGATGACGGAGAACTTGGAGAGGCACCAGGAGAAGCTGGAGGAGAAGCAGGCGGCTTGCCTGGAACAGATACGGGAGATGGAAAA
GCAGGTGACCTTGGAGAAGGTGCTGGGAATTACAGTGTCTGGAGGCAGAGGACTTGCCTGTGACCCCCGATCAGGTTTAGTTGCTTACCC
AGCAGGGTGTGTGGTTGTGTTGTTCAATCCCCGGAAACACAAACAGCACCACATCCTCAACAGTTCCAGGAAAACCATCACTGCCCTTGC
CTTCTCCCCTGATGGCAAGTACTTGGTCACTGGAGAGAGTGGGCACATGCCTGCCGTGCGGGTTTGGGACGTGGCAGAGCACAGCCAGGT
GGCCGAGCTGCAGGAGCACAAGTATGGTGTGGCTTGTGTGGCCTTCTCTCCTAGCGCCAAGTACATTGTCTCTGTGGGCTACCAGCATGA
CATGATCGTCAACGTGTGGGCCTGGAAGAAAAACATTGTGGTGGCCTCCAACAAGGTGTCCAGTCGGGTGACAGCAGTGTCCTTCTCTGA
GGATTGCAGCTACTTTGTCACTGCAGGCAACCGACACATCAAATTCTGGTATCTCGATGACAGCAAGACCTCAAAGGTGAATGCCACTGT
GCCCTTGCTGGGCCGCTCAGGGCTGCTGGGAGAGCTACGGAACAACCTATTCACTGATGTGGCCTGTGGCAGAGGAAAAAAGGCGGACAG
TACCTTCTGCATCACGTCCTCAGGGCTGCTGTGCGAGTTCAGTGATCGAAGGCTTTTGGACAAGTGGGTGGAGCTGAGGACCACAGTGGC
CCACTGCATCTCTGTGAGCCAAGACTACATCTTCTGTGGCTGTGCTGATGGCACCGTGCGCCTTTTCAACCCCTCTAACCTGCACTTCCT
TAGCACCTTGCCCCGACCCCATGCTCTGGGGACAGACATTGCTAGCGTCACCGAGGCCAGTCGCCTCTTCTCTGGAGTGGCGAATGCCAG
GTATCCAGACACCATTGCCTTGACCTTTGATCCTACTAATCAGTGGCTGTCTTGTGTGTACAACGATCATAGCATTTATGTTTGGGATGT
GAGGGACCCCAAGAAAGTGGGCAAGGTGTACTCGGCTCTGTATCATTCTTCCTGCGTCTGGAGTGTGGAGGTCTACCCCGAGGTGAAGGA
TAGTAACCAGGCCTGCCTGCCCCCCAGTTCCTTTATTACCTGCTCCTCAGACAACACCATCCGCCTGTGGAACACAGAGAGCTCCGGGGT
GCATGGCTCCACCCTCCACCGAAACATCCTCAGCAGTGACCTCATTAAAATCATCTATGTGGATGGGAACACCCAGGCCCTGCTGGACAC
AGAGCTGCCTGGAGGAGACAAAGCTGATGCATCCCTGTTGGATCCCCGCGTGGGCATCCGCTCGGTGTGTGTCAGCCCCAATGGACAGCA
TCTAGCATCAGGGGACCGTATGGGCACACTTAGGGTGCACGAACTTCAGTCCCTGAGTGAGATGCTGAAGGTGGAGGCCCATGACTCTGA
GATTCTGTGCCTGGAGTATTCTAAGCCAGACACAGGTCTGAAACTGCTAGCATCGGCGAGCCGGGACCGGCTGATCCATGTGCTGGATGC
CGGGCGGGAGTACAGCCTACAGCAGACGCTGGACGAACACTCATCCTCCATCACTGCTGTTAAGTTTGCAGCCAGTGATGGGCAAGTCCG
CATGATCAGCTGTGGAGCAGACAAGAGCATCTACTTCCGCACTGCGCAGAAGTCTGGAGATGGAGTGCAGTTCACACGGACACACCACGT
GGTGCGGAAGACGACCCTCTATGACATGGATGTGGAGCCCAGCTGGAAGTACACGGCTATCGGCTGCCAGGACCGAAATATTCGGATATT
TAACATCAGCAGTGGAAAGCAGAAGAAGCTGTTTAAAGGGTCACAGGGTGAGGACGGCACACTCATTAAGGTGCAGACAGACCCCTCAGG
GATCTACATTGCCACCAGCTGTTCTGACAAGAATCTCTCCATTTTTGACTTCTCCTCAGGCGAGTGCGTGGCCACCATGTTTGGCCACTC
AGAGATTGTCACTGGCATGAAATTTAGTAATGATTGTAAACATCTCATCTCTGTGTCTGGGGACAGCTGCATATTTGTGTGGCGCCTGAG
CTCTGAGATGACCATCAGCATGAGGCAGCGTCTGGCCGAGTTGCGCCAGCGTCAGCGGGGCGGCAAGCAGCAAGGACCATCCTCTCCCCA
AAGGGCTTCTGGACCCAACCGGCACCAGGCCCCATCAATGCTGTCTCCTGGACCGGCTCTCTCATCAGACAGTGACAAGGAGGGAGAAGA
TGAGGGGACTGAAGAAGAACTTCCAGCACTGCCCGTCCTTGCCAAGAGTACCAAGAAGGCACTGGCCTCGGTCCCCAGCCCAGCTTTGCC
CCGAAGCCTGTCCCACTGGGAGATGAGTCGGGCACAGGAGTCCGTGGGGTTCCTGGACCCAGCTCCTGCAGCCAACCCAGGACCCAGAAG
AAGAGGGCGCTGGGTTCAGCCAGGTGTGGAACTGAGCGTTAGATCCATGCTGGATCTGCGGCAGCTGGAAACACTGGCCCCAAGCCTGCA
GGACCCTAGCCAGGACTCGCTGGCCATCATCCCATCTGGTCCCAGGAAGCATGGGCAGGAGGCCCTTGAGACTTCACTCACTAGCCAGAA
TGAAAAGCCCCCTCGGCCTCAGGCTTCCCAACCTTGTTCCTATCCCCATATTATCCGATTATTGTCACAAGAGGAAGGGGTCTTTGCCCA
AGATCTGGAACCTGCACCCATTGAAGATGGTATTGTCTACCCGGAGCCGAGTGACAACCCCACCATGGATACCAGTGAGTTCCAAGTGCA
GGCTCCAGCCCGGGGAACTCTGGGAAGAGTGTACCCAGGCAGCAGGAGCTCAGAAAAGCACAGCCCTGACAGTGCCTGCTCTGTGGATTA
CAGCAGCAGCTGCCTTTCCAGCCCGGAGCACCCCACTGAAGACTCTGAGAGCACGGAGCCCCTCAGTGTGGATGGCATCTCCTCAGACCT
TGAAGAGCCAGCTGAGGGTGATGAAGAAGAGGAAGAAGAGGAGGGAGGCATGGGCCCCTATGGGCTACAGGAGGGCAGCCCCCAGACTCC
AGACCAGGAGCAGTTTCTAAAACAGCACTTTGAGACTCTGGCCAGTGGAGCTGCTCCAGGGGCCCCAGTGCAGGTCCCAGAGAGGTCAGA
GTCTCGGAGTATCTCTTCACGATTCCTGTTGCAAGTACAGACCCGCCCACTCAGGGAACCATCCCCATCCTCCTCAAGCCTGGCACTGAT
GTCGAGACCAGCCCAGGTGCCACAGGCATCTGGTGAGCAGCCGAGAGGCAATGGTGCCAATCCCCCTGGAGCACCCCCGGAGGTGGAACC
GTCCTCTGGCAACCCCAGCCCCCAGCAGGCAGCCTCTGTGCTGTTGCCACGATGCCGTCTCAACCCTGACAGCAGCTGGGCTCCCAAGAG
AGTGGCCACAGCCAGCCCCTTTTCTGGACTCCAGAAGGCCCAGTCTGTGCACAGTCTGGTGCCACAGGAAAGACATGAGGCCAGTCTGCA
GGCCCCTTCACCAGGCGCACTGCTGTCTCGGGAGATCGAAGCTCAGGATGGTCTGGGCTCCCTGCCCCCAGCTGATGGCCGTCCGTCTCG
GCCTCACTCCTATCAGAACCCCACCACCAGTTCCATGGCCAAGATATCCCGCAGTATCTCTGTTGGGGAGAACCTGGGCCTGGTGGCTGA
ACCTCAAGCTCATGCCCCCATCCGAGTCTCACCACTCAGCAAGCTGGCCCTGCCCAGCCGGGCTCACCTGGTCCTGGACATCCCCAAACC
ACTGCCTGACCGTCCTACCCTGGCTGCATTCTCTCCTGTCACCAAAGGCCGGGCCCCTGGCGAGGCAGAAAAGCCTGGCTTCCCGGTGGG
CCTAGGAAAAGCTCACAGTACAACTGAGAGATGGGCCTGTTTGGGGGAGGGCACCACTCCCAAGCCTAGGACAGAGTGCCAGGCTCATCC
TGGGCCCAGCAGCCCCTGTGCCCAGCAACTGCCAGTCAGCAGCCTCTTCCAAGGCCCTGAAAACTTGCAGCCCCCACCCCCTGAGAAGAC
TCCCAACCCCATGGAATGCACCAAGCCAGGGGCAGCCCTGAGCCAGGACTCAGAGCCAGCGGTGAGCCTGGAGCAGTGTGAGCAGCTGGT
GGCAGAGCTCCGCGGCAGCGTGCGCCAGGCAGTGCGGCTCTACCACTCGGTGGCTGGCTGCAAGATGCCCTCAGCAGAGCAAAGTCGGAT
TGCCCAGCTCCTCAGAGACACCTTCTCTTCAGTGCGACAGGAGCTGGAAGCTGTGGCTGGGGCAGTGCTGTCCAGCCCAGGCAGCAGCCC
TGGGGCTGTGGGAGCCGAGCAGACACAGGCCCTGCTGGAGCAATACTCAGAACTGTTGCTTCGAGCCGTGGAACGGCGTATGGAACGCAA
ACTCTGAGTTCTGGAAGCCTGTCCCAAGTGAATGAATGCTCCAGCGATTCCAAACTGCAGCCCCTCTGCCCCTCACCAAAACCTGCGGGG
CTGCTTGGAGTGGAAAGCAGGGAGCAGTGTTCAGAGGCAAAGCAGCCTTCCCAGCCGCTCCTCGTGGGGGGCCTGTATTTATTAATTTAT
TTCCCTGACTGTTGCCTCACTTCCTTGGAACTCCTGCCTCCACAGCCCCTCCAGTGGCAGGGACAGGTCTTGGGTCTTTGTCATCTTGGT
GCTGTGAGAGGTAGGAGGGCAGCCTGCCCCATCTAGGAATCTGGGAAGGGCTGGCCCTCTCTTAGAAGCCATTTGAAATTACTGCAGGGA
TTAGCTCCCTGTGGTGGAGCATACACAGGGTACTCTGGGGTCGAGGTGAGAGGTGATGTGGTATTCAGTGCCCGTCAGCCAACTGTGGGC
CTTCACCTCTACCTGCACTTCCCCTCTCACACCAGCTGCACTCCCGTGGCTGCCAGAGCAGGGTGGTTTTCCCCAATACCTGGAGCTCAG
AAAGGCAGAGCCATCTGGCCCTCCAGGGTGTCCCCAGCCATCAGGAGACTTGAGTTGGTATTTGGACCTGAGCCCGCACATTCCACTCCC
ATTCTCCCTCCAAGAGGGGCCCAGCATTGTATTTCCCTGTGACCCCTTACTCTCCTGGCCAGAACTTGAGCCAGCTGTGGGATGTTGCTG
CAGGACAGTAAGCCCTCACCTGGGCAAACATGAAGCTCTGGCCTCCTTTCCTCAGCCCCTTGTTCTTCCCTGTCCTCCACCCTGGACCCC
AGCCGGCTGCTGGAGCCCAGAGGCCACCTTCTCCCTGCATCCTGAATGATGCTTAGTCAGAAGCCTGTGTTGGAACATCCCTCGTTTACG
GGGCGCTGGCCTACCTCCTGAGGACCTCAGCCACAGATGAGATCACACGCATGCACGTGCACACATGTACACACACACACCTACCTGCAC
AGCACGCTGTTGAGTGTTGGTTGCTAGAGTATCTGGCTGGCTGCTGTGTGCCTGGTTTCCTCACATCCTGCCTCAGCTTCACCACCCTGG
CTTATGTGGAACACCTATCAGGGAGCAGAAAAGGGGTGCAGTACACTAAGTGAACCCAGATTCTGGATTCTTGGTGTCCACAGCCTAGCT
GATACGAGATAGCCCATAGGACACCTGGTTTAGGTAGAAGGAGCCTCCTCAAAGGCAGTGCTGGGCACCCACGGGTGTGCTGGATACTGG
AGTTTGAGAGGAGGGAGGTGCTGGGGCCAAAGGAGACACTAGAAAAGTGGTAGATGGGACAGGTAAGTGGCAGAGGTGAGGGGATAAGTT
AGAATGTAAAAGGGCAGTAATTAGGGGTGAGGGAAAGGAGATAGGGGACCCTAGGAGGTAGAGTGGGACCATGTCGTGAGGCAGTTGAAG
AGTTGAGGAAAGGTTTTTCTGGGCCCTACTGCTCCCCTCTGCTGCAGGTAAGTCAGAGCAGCTTTACCACAGCTTCAGGCCACGAGAGCC
CCTTCACCCGCCCTGCTGCGCCATAGGCAGAGGCTTATAAAGAAATGGGTTCTGGGCCAGGTGTGGTGGCTCAAGCCTGTAATCCCAGCA
CTTTGGGAGGCCGAGGCGGGTGGATCACCTGAGGTTAGGAGTTCGAGATCAGCCTGGCCAACATGGTGAAACCCTGTCTACTAAAAATAA
AAAAATTAGCTGGGCGTGGTGGTGGGCGCCTGTAATCCCAGCTACTCGGGAGGTTTAGGCAGGAGAATCGCTTGAACCCTGGAGGTGGAG
GTGGAGGTTGCAGTGAGCCGAGATCGCGCCATTGCACTCCAACCTAGGTGACAAAGCTACACGCCATCTCAAAAAAAAAAAAGAAAAAGG
GTTACAAAAGGTTCCCAGCTCCGGGGCATCAGCCTGAGTGCGCTTGAGCTGCTCCAAACCTGGCCCTTCCCCACTCCTCTAGCATCGCCA
CCCGCATGGCCCTGGAACTCCCGCGGCGGCGGGGGCGGGCCCGTGCCTGCTGTGCCCCGACTTCCCACACCAGCCGCGCCCACCGCAGGT
GGGACTCAGGTTCGCCCTCTGGGCCAGGTCCTTCACGAGGAGGGAGCTACCCTTCGCCAGAAGTTTGTGAGAATGTGGCCGCCCTTTTCC
TGCCCTCTGCCCCATGTGGGTGGGGGGCCTCGTGGCCCGGCCGGCGCCCCGTCCCCTTCTGCATGTCTGAGGCCACCGGCAACCGCCGCC
CCACTCCAGATTTGCCCCCGCCTTGTTTTGAAAGCCCCTTATTTATAACTTTTATACTTTGTGCAGGTCGCGGCGCTTCCTGCCTCATCC

>In-frame_ENST00000260402_ENST00000457542_TCGA-3H-AB3M-01A_PLCB2_chr15_40581473_-_MAPKBP1_chr15_42092021_length(amino acids)=2611AA_start in transcript=181_stop in transcript=8016
MASFLPFCLPVSAEILQRGTLGTMSLLNPVLLPPKVKAYLSQGERFIKWDDETTVASPVILRVDPKGYYLYWTYQSKEMEFLDITSIRDT
RFGKFAKMPKSQKLRDVFNMDFPDNSFLLKTLTVVSGPDMVDLTFHNFVSYKENVGKAWAEDVLALVKHPLTANASRSTFLDKILVKLKM
QLNSEGKIPVKNFFQMFPADRKRVEAALSACHLPKGKNDAINPEDFPEPVYKSFLMSLCPRPEIDEIFTSYHAKAKPYMTKEHLTKFINQ
KQRDSRLNSLLFPPARPDQVQGLIDKYEPSGINAQRGQLSPEGMVWFLCGPENSVLAQDKLLLHHDMTQPLNHYFINSSHNTYLTAGQFS
GLSSAEMYRQVLLSGCRCVELDCWKGKPPDEEPIITHGFTMTTDIFFKEAIEAIAESAFKTSPYPIILSFENHVDSPRQQAKMAEYCRTI
FGDMLLTEPLEKFPLKPGVPLPSPEDLRGKILIKNKKNQFSGPTSSSKDTGGEAEGSSPPSAPAGEGTVWAGEEGTELEEEEVEEEEEEE
SGNLDEEEIKKMQSDEGTAGLEVTAYEEMSSLVNYIQPTKFVSFEFSAQKNRSYVISSFTELKAYDLLSKASVQFVDYNKRQMSRIYPKG
TRMDSSNYMPQMFWNAGCQMVALNFQTMDLPMQQNMAVFEFNGQSGYLLKHEFMRRPDKQFNPFSVDRIDVVVATTLSITVISGQFLSER
SVRTYVEVELFGLPGDPKRRYRTKLSPSTNSINPVWKEEPFVFEKILMPELASLRVAVMEEGNKFLGHRIIPINALNSGYHHLCLHSESN
MPLTMPALFIFLEMKDYIPGAWADLTVALANPIKFFSAHDTKSVKLKEAMGGLPEKPFPLASPVASQVNGALAPTSNGSPAARAGAREEA
MKEAAEPRTASLEELRELKGVVKLQRRHEKELRELERRGARRWEELLQRGAAQLAELGPPGVGGVGACKLGPGKGSRKKRSLPREESAGA
APGEGPEGVDGRVRELKDRLELELLRQGEEQYECVLKRKEQHVAEQISKMMELAREKQAAELKALKETSENDTKEMKKKLETKRLERIQG
MTKVTTDKMAQERLKREINNSHIQEVVQVIKQMTENLERHQEKLEEKQAACLEQIREMEKQVTLEKVLGITVSGGRGLACDPRSGLVAYP
AGCVVVLFNPRKHKQHHILNSSRKTITALAFSPDGKYLVTGESGHMPAVRVWDVAEHSQVAELQEHKYGVACVAFSPSAKYIVSVGYQHD
MIVNVWAWKKNIVVASNKVSSRVTAVSFSEDCSYFVTAGNRHIKFWYLDDSKTSKVNATVPLLGRSGLLGELRNNLFTDVACGRGKKADS
TFCITSSGLLCEFSDRRLLDKWVELRTTVAHCISVSQDYIFCGCADGTVRLFNPSNLHFLSTLPRPHALGTDIASVTEASRLFSGVANAR
YPDTIALTFDPTNQWLSCVYNDHSIYVWDVRDPKKVGKVYSALYHSSCVWSVEVYPEVKDSNQACLPPSSFITCSSDNTIRLWNTESSGV
HGSTLHRNILSSDLIKIIYVDGNTQALLDTELPGGDKADASLLDPRVGIRSVCVSPNGQHLASGDRMGTLRVHELQSLSEMLKVEAHDSE
ILCLEYSKPDTGLKLLASASRDRLIHVLDAGREYSLQQTLDEHSSSITAVKFAASDGQVRMISCGADKSIYFRTAQKSGDGVQFTRTHHV
VRKTTLYDMDVEPSWKYTAIGCQDRNIRIFNISSGKQKKLFKGSQGEDGTLIKVQTDPSGIYIATSCSDKNLSIFDFSSGECVATMFGHS
EIVTGMKFSNDCKHLISVSGDSCIFVWRLSSEMTISMRQRLAELRQRQRGGKQQGPSSPQRASGPNRHQAPSMLSPGPALSSDSDKEGED
EGTEEELPALPVLAKSTKKALASVPSPALPRSLSHWEMSRAQESVGFLDPAPAANPGPRRRGRWVQPGVELSVRSMLDLRQLETLAPSLQ
DPSQDSLAIIPSGPRKHGQEALETSLTSQNEKPPRPQASQPCSYPHIIRLLSQEEGVFAQDLEPAPIEDGIVYPEPSDNPTMDTSEFQVQ
APARGTLGRVYPGSRSSEKHSPDSACSVDYSSSCLSSPEHPTEDSESTEPLSVDGISSDLEEPAEGDEEEEEEEGGMGPYGLQEGSPQTP
DQEQFLKQHFETLASGAAPGAPVQVPERSESRSISSRFLLQVQTRPLREPSPSSSSLALMSRPAQVPQASGEQPRGNGANPPGAPPEVEP
SSGNPSPQQAASVLLPRCRLNPDSSWAPKRVATASPFSGLQKAQSVHSLVPQERHEASLQAPSPGALLSREIEAQDGLGSLPPADGRPSR
PHSYQNPTTSSMAKISRSISVGENLGLVAEPQAHAPIRVSPLSKLALPSRAHLVLDIPKPLPDRPTLAAFSPVTKGRAPGEAEKPGFPVG
LGKAHSTTERWACLGEGTTPKPRTECQAHPGPSSPCAQQLPVSSLFQGPENLQPPPPEKTPNPMECTKPGAALSQDSEPAVSLEQCEQLV
AELRGSVRQAVRLYHSVAGCKMPSAEQSRIAQLLRDTFSSVRQELEAVAGAVLSSPGSSPGAVGAEQTQALLEQYSELLLRAVERRMERK

--------------------------------------------------------------
>In-frame_ENST00000557821_ENST00000221214_TCGA-3H-AB3M-01A_PLCB2_chr15_40581473_-_MAPKBP1_chr15_42092021_length(transcript)=9986nt_BP=3507nt
CAGCCAGGGCCACCCCAGGGGCTATAAGAGCAACTAGATTTCTGGAGCAGCTCGGGGATGGGTGCCATTTGAGCCCAGCTTGGCTCCCCC
TCCTGGCTGGCCTCCTTCCTGCCCTTCTGCCTGCCTGTGTCTGCTGAGATTCTGCAAAGAGGAACGCTTGGCACCATGTCTCTGCTCAAC
CCTGTCCTGCTGCCCCCCAAGGTGAAGGCCTATCTGAGCCAAGGGGAGCGCTTCATCAAATGGGATGATGAAACTACAGTTGCCTCTCCA
GTTATCCTCCGTGTGGATCCTAAGGGCTACTACTTATACTGGACGTATCAAAGTAAGGAGATGGAGTTTCTGGATATCACCAGCATCCGG
GATACTCGCTTTGGGAAGTTTGCCAAGATGCCCAAGAGCCAGAAGCTCCGGGACGTCTTCAACATGGACTTTCCTGATAACAGTTTCCTG
CTGAAGACACTCACGGTGGTGTCCGGCCCGGACATGGTGGACCTCACCTTCCACAACTTCGTCTCCTACAAGGAGAACGTGGGCAAGGCC
TGGGCTGAGGACGTACTGGCCCTAGTCAAACATCCGCTGACGGCCAACGCCTCCCGCAGCACCTTCCTGGACAAGATCCTTGTGAAGCTC
AAGATGCAGCTCAACTCTGAAGGGAAGATTCCGGTGAAGAACTTTTTCCAGATGTTTCCTGCTGACCGCAAGCGGGTGGAAGCTGCTCTC
AGTGCCTGCCACCTCCCCAAAGGCAAAAATGACGCCATCAATCCTGAGGACTTCCCAGAACCTGTCTACAAGAGTTTCCTCATGAGCCTC
TGTCCTCGGCCAGAAATAGATGAGATCTTCACTTCTTACCATGCTAAGGCCAAACCCTACATGACGAAGGAGCACCTGACCAAATTCATC
AACCAGAAACAGCGGGACTCCCGGCTTAACTCCCTGCTGTTCCCGCCAGCACGGCCTGACCAGGTGCAGGGCCTCATCGACAAGTATGAG
CCCAGTGGCATCAATGCACAGAGGGGCCAGCTGTCACCTGAAGGCATGGTCTGGTTTCTCTGTGGGCCAGAGAACAGCGTGCTGGCCCAG
GACAAGCTGCTGCTCCACCACGACATGACGCAGCCACTCAATCATTACTTCATCAACTCGTCCCACAACACCTACCTGACAGCCGGCCAG
TTCTCAGGCCTCTCCTCGGCTGAGATGTACCGCCAGGTGCTGCTCTCTGGCTGCCGTTGCGTGGAGCTAGACTGCTGGAAGGGGAAACCC
CCTGACGAGGAGCCCATTATCACCCATGGCTTCACCATGACCACAGACATCTTCTTCAAAGAAGCAATTGAGGCTATTGCAGAAAGCGCC
TTTAAGACCTCCCCCTATCCCATCATCCTGTCGTTTGAGAACCATGTGGACTCACCCCGCCAGCAGGCTAAGATGGCTGAGTATTGCCGG
ACGATCTTTGGGGATATGCTGCTCACAGAGCCCCTGGAAAAGTTCCCACTAAAACCAGGTGTCCCCCTGCCCAGCCCTGAGGATCTCAGG
GGCAAGATCCTCATCAAGAACAAGAAGAACCAGTTTTCTGGCCCCACCTCCTCCAGTAAGGATACTGGTGGGGAGGCTGAGGGCAGCAGC
CCACCCAGTGCCCCTGCAGTGTGGGCTGGCGAGGAAGGGACTGAGCTGGAGGAGGAGGAGGTGGAAGAGGAAGAGGAGGAGGAGTCAGGA
AACCTGGATGAAGAAGAGATTAAGAAGATGCAGTCGGATGAGGGCACAGCGGGCCTGGAAGTGACGGCTTATGAGGAGATGTCCAGCCTA
GTCAATTACATCCAGCCCACCAAGTTCGTCTCCTTTGAGTTCTCTGCCCAAAAGAACCGAAGTTATGTCATCTCGTCCTTCACAGAGCTC
AAGGCATATGACCTGCTCTCCAAGGCCTCGGTGCAGTTTGTGGACTACAACAAGCGCCAGATGAGCCGCATTTACCCCAAGGGAACCCGC
ATGGACTCCTCCAACTACATGCCCCAGATGTTCTGGAATGCTGGATGCCAGATGGTTGCCCTCAACTTCCAGACGATGGACTTGCCCATG
CAGCAGAACATGGCAGTATTTGAGTTCAACGGGCAGAGCGGCTACCTCCTCAAGCATGAGTTCATGCGCCGGCCGGACAAGCAGTTCAAC
CCCTTCTCAGTGGACCGCATCGACGTGGTGGTGGCCACCACCCTTTCCATTACGGTGATCTCTGGGCAGTTCCTGTCAGAACGCAGCGTG
CGCACCTATGTAGAAGTGGAGCTGTTTGGCCTTCCTGGGGACCCCAAGAGGCGCTATCGAACTAAGCTGTCACCCAGTACTAACTCCATC
AATCCTGTCTGGAAGGAGGAGCCCTTTGTCTTTGAGAAGATCTTGATGCCTGAGCTGGCCTCCCTCAGAGTGGCTGTGATGGAGGAAGGC
AACAAGTTTCTTGGACACCGCATCATCCCCATCAATGCCCTAAATTCTGGGTACCACCACCTGTGCCTGCACAGTGAGAGCAACATGCCC
CTCACCATGCCTGCGCTCTTCATCTTCCTGGAGATGAAGGACTACATACCTGGTGCTTGGGCAGATCTCACTGTGGCCCTCGCCAACCCC
ATTAAGTTCTTCAGTGCCCATGACACGAAGTCTGTGAAGCTCAAGGAGGCCATGGGAGGTCTGCCTGAGAAGCCCTTCCCACTGGCGAGT
CCAGTTGCCAGCCAGGTCAATGGGGCGTTGGCCCCAACGAGCAATGGGTCACCAGCAGCCAGGGCCGGGGCCAGGGAAGAGGCTATGAAA
GAAGCTGCGGAGCCGCGGACCGCCAGCCTGGAGGAGCTCCGGGAGCTAAAGGGCGTGGTGAAGCTGCAGCGGCGGCACGAGAAGGAGCTG
CGAGAGTTGGAGCGGCGCGGAGCGCGGCGCTGGGAGGAGCTGCTGCAGCGGGGCGCGGCGCAGCTGGCGGAGCTCGGGCCACCGGGCGTG
GGGGGCGTCGGGGCCTGCAAGCTCGGTCCCGGCAAGGGCTCTCGCAAGAAGAGGAGCCTGCCCCGCGAGGAGAGCGCCGGAGCCGCGCCG
GGCGAGGGCCCTGAGGGCGTGGACGGGCGCGTGCGGGAGCTGAAAGACAGGCTGGAGCTGGAGCTGCTGCGGCAGGGCGAGGAGCAGTAC
GAGTGCGTTCTGAAGCGCAAGGAGCAGCACGTGGCCGAGCAAATCTCCAAAATGATGGAGCTGGCCAGAGAGAAACAGGCGGCAGAGCTG
AAGGCCCTGAAGGAGACGTCGGAGAACGACACCAAAGAGATGAAGAAAAAGCTGGAGACAAAGAGACTGGAGCGGATCCAGGGCATGACC
AAAGTCACCACAGACAAGATGGCCCAGGAGAGGTTGAAGAGAGAGATTAACAACTCCCACATCCAGGAAGTAGTGCAGGTGATCAAGCAG
ATGACGGAGAACTTGGAGAGGCACCAGGAGAAGCTGGAGGAGAAGCAGGCGGCTTGCCTGGAACAGATACGGGAGATGGAAAAGCAGGTG
ACCTTGGAGAAGGTGCTGGGAATTACAGTGTCTGGAGGCAGAGGACTTGCCTGTGACCCCCGATCAGGTTTAGTTGCTTACCCAGCAGGG
TGTGTGGTTGTGTTGTTCAATCCCCGGAAACACAAACAGCACCACATCCTCAACAGTTCCAGGAAAACCATCACTGCCCTTGCCTTCTCC
CCTGATGGCAAGTACTTGGTCACTGGAGAGAGTGGGCACATGCCTGCCGTGCGGGTTTGGGACGTGGCAGAGCACAGCCAGGTGGCCGAG
CTGCAGGAGCACAAGTATGGTGTGGCTTGTGTGGCCTTCTCTCCTAGCGCCAAGTACATTGTCTCTGTGGGCTACCAGCATGACATGATC
GTCAACGTGTGGGCCTGGAAGAAAAACATTGTGGTGGCCTCCAACAAGGTGTCCAGTCGGGTGACAGCAGTGTCCTTCTCTGAGGATTGC
AGCTACTTTGTCACTGCAGGCAACCGACACATCAAATTCTGGTATCTCGATGACAGCAAGACCTCAAAGGTGAATGCCACTGTGCCCTTG
CTGGGCCGCTCAGGGCTGCTGGGAGAGCTACGGAACAACCTATTCACTGATGTGGCCTGTGGCAGAGGAAAAAAGGCGGACAGTACCTTC
TGCATCACGTCCTCAGGGCTGCTGTGCGAGTTCAGTGATCGAAGGCTTTTGGACAAGTGGGTGGAGCTGAGGGTCTACCCCGAGGTGAAG
GATAGTAACCAGGCCTGCCTGCCCCCCAGTTCCTTTATTACCTGCTCCTCAGACAACACCATCCGCCTGTGGAACACAGAGAGCTCCGGG
GTGCATGGCTCCACCCTCCACCGAAACATCCTCAGCAGTGACCTCATTAAAATCATCTATGTGGATGGGAACACCCAGGCCCTGCTGGAC
ACAGAGCTGCCTGGAGGAGACAAAGCTGATGCATCCCTGTTGGATCCCCGCGTGGGCATCCGCTCGGTGTGTGTCAGCCCCAATGGACAG
CATCTAGCATCAGGGGACCGTATGGGCACACTTAGGGTGCACGAACTTCAGTCCCTGAGTGAGATGCTGAAGGTGGAGGCCCATGACTCT
GAGATTCTGTGCCTGGAGTATTCTAAGCCAGACACAGGTCTGAAACTGCTAGCATCGGCGAGCCGGGACCGGCTGATCCATGTGCTGGAT
GCCGGGCGGGAGTACAGCCTACAGCAGACGCTGGACGAACACTCATCCTCCATCACTGCTGTTAAGTTTGCAGCCAGTGATGGGCAAGTC
CGCATGATCAGCTGTGGAGCAGACAAGAGCATCTACTTCCGCACTGCGCAGAAGTCTGGAGATGGAGTGCAGTTCACACGGACACACCAC
GTGGTGCGGAAGACGACCCTCTATGACATGGATGTGGAGCCCAGCTGGAAGTACACGGCTATCGGCTGCCAGGACCGAAATATTCGGATA
TTTAACATCAGCAGTGGAAAGCAGAAGAAGCTGTTTAAAGGGTCACAGGGTGAGGACGGCACACTCATTAAGGTGCAGACAGACCCCTCA
GGGATCTACATTGCCACCAGCTGTTCTGACAAGAATCTCTCCATTTTTGACTTCTCCTCAGGCGAGTGCGTGGCCACCATGTTTGGCCAC
TCAGAGATTGTCACTGGCATGAAATTTAGTAATGATTGTAAACATCTCATCTCTGTGTCTGGGGACAGCTGCATATTTGTGTGGCGCCTG
AGCTCTGAGATGACCATCAGCATGAGGCAGCGTCTGGCCGAGTTGCGCCAGCGTCAGCGGGGCGGCAAGCAGCAAGGACCATCCTCTCCC
CAAAGGGCTTCTGGACCCAACCGGCACCAGGCCCCATCAATGCTGTCTCCTGGACCGGCTCTCTCATCAGACAGTGACAAGGAGGGAGAA
GATGAGGGGACTGAAGAAGAACTTCCAGCACTGCCCGTCCTTGCCAAGAGTACCAAGAAGGCACTGGCCTCGGTCCCCAGCCCAGCTTTG
CCCCGAAGCCTGTCCCACTGGGAGATGAGTCGGGCACAGGAGTCCGTGGGGTTCCTGGACCCAGCTCCTGCAGCCAACCCAGGACCCAGA
AGAAGAGGGCGCTGGGTTCAGCCAGGTGTGGAACTGAGCGTTAGATCCATGCTGGATCTGCGGCAGCTGGAAACACTGGCCCCAAGCCTG
CAGGACCCTAGCCAGGACTCGCTGGCCATCATCCCATCTGGTCCCAGGAAGCATGGGCAGGAGGCCCTTGAGACTTCACTCACTAGCCAG
AATGAAAAGCCCCCTCGGCCTCAGGCTTCCCAACCTTGTTCCTATCCCCATATTATCCGATTATTGTCACAAGAGGAAGGGGTCTTTGCC
CAAGATCTGGAACCTGCACCCATTGAAGATGGTATTGTCTACCCGGAGCCGAGTGACAACCCCACCATGGATACCAGTGAGTTCCAAGTG
CAGGCTCCAGCCCGGGGAACTCTGGGAAGAGTGTACCCAGGCAGCAGGAGCTCAGAAAAGCACAGCCCTGACAGTGCCTGCTCTGTGGAT
TACAGCAGCAGCTGCCTTTCCAGCCCGGAGCACCCCACTGAAGACTCTGAGAGCACGGAGCCCCTCAGTGTGGATGGCATCTCCTCAGAC
CTTGAAGAGCCAGCTGAGGGTGATGAAGAAGAGGAAGAAGAGGAGGGAGGCATGGGCCCCTATGGGCTACAGGAGGGCAGCCCCCAGACT
CCAGACCAGGAGCAGTTTCTAAAACAGCACTTTGAGACTCTGGCCAGTGGAGCTGCTCCAGGGGCCCCAGTGCAGGTCCCAGAGAGGTCA
GAGTCTCGGAGTATCTCTTCACGATTCCTGTTGCAAGTACAGACCCGCCCACTCAGGGAACCATCCCCATCCTCCTCAAGCCTGGCACTG
ATGTCGAGACCAGCCCAGGTGCCACAGGCATCTGGTGAGCAGCCGAGAGGCAATGGTGCCAATCCCCCTGGAGCACCCCCGGAGGTGGAA
CCGTCCTCTGGCAACCCCAGCCCCCAGCAGGCAGCCTCTGTGCTGTTGCCACGATGCCGTCTCAACCCTGACAGCAGCTGGGCTCCCAAG
AGAGTGGCCACAGCCAGCCCCTTTTCTGGACTCCAGAAGGCCCAGTCTGTGCACAGTCTGGTGCCACAGGAAAGACATGAGGCCAGTCTG
CAGGCCCCTTCACCAGGCGCACTGCTGTCTCGGGAGATCGAAGCTCAGGATGGTCTGGGCTCCCTGCCCCCAGCTGATGGCCGTCCGTCT
CGGCCTCACTCCTATCAGAACCCCACCACCAGTTCCATGGCCAAGATATCCCGCAGTATCTCTGTTGGGGAGAACCTGGGCCTGGTGGCT
GAACCTCAAGCTCATGCCCCCATCCGAGTCTCACCACTCAGCAAGCTGGCCCTGCCCAGCCGGGCTCACCTGGTCCTGGACATCCCCAAA
CCACTGCCTGACCGTCCTACCCTGGCTGCATTCTCTCCTGTCACCAAAGGCCGGGCCCCTGGCGAGGCAGAAAAGCCTGGCTTCCCGGTG
GGCCTAGGAAAAGCTCACAGTACAACTGAGAGATGGGCCTGTTTGGGGGAGGGCACCACTCCCAAGCCTAGGACAGAGTGCCAGGCTCAT
CCTGGGCCCAGCAGCCCCTGTGCCCAGCAACTGCCAGTCAGCAGCCTCTTCCAAGGCCCTGAAAACTTGCAGCCCCCACCCCCTGAGAAG
ACTCCCAACCCCATGGAATGCACCAAGCCAGGGGCAGCCCTGAGCCAGGACTCAGAGCCAGCGGTGAGCCTGGAGCAGTGTGAGCAGCTG
GTGGCAGAGCTCCGCGGCAGCGTGCGCCAGGCAGTGCGGCTCTACCACTCGGTGGCTGGCTGCAAGATGCCCTCAGCAGAGCAAAGTCGG
ATTGCCCAGCTCCTCAGAGACACCTTCTCTTCAGTGCGACAGGAGCTGGAAGCTGTGGCTGGGGCAGTGCTGTCCAGCCCAGGCAGCAGC
CCTGGGGCTGTGGGAGCCGAGCAGACACAGGCCCTGCTGGAGCAATACTCAGAACTGTTGCTTCGAGCCGTGGAACGGCGTATGGAACGC
AAACTCTGAGTTCTGGAAGCCTGTCCCAAGTGAATGAATGCTCCAGCGATTCCAAACTGCAGCCCCTCTGCCCCTCACCAAAACCTGCGG
GGCTGCTTGGAGTGGAAAGCAGGGAGCAGTGTTCAGAGGCAAAGCAGCCTTCCCAGCCGCTCCTCGTGGGGGGCCTGTATTTATTAATTT
ATTTCCCTGACTGTTGCCTCACTTCCTTGGAACTCCTGCCTCCACAGCCCCTCCAGTGGCAGGGACAGGTCTTGGGTCTTTGTCATCTTG
GTGCTGTGAGAGGTAGGAGGGCAGCCTGCCCCATCTAGGAATCTGGGAAGGGCTGGCCCTCTCTTAGAAGCCATTTGAAATTACTGCAGG
GATTAGCTCCCTGTGGTGGAGCATACACAGGGTACTCTGGGGTCGAGGTGAGAGGTGATGTGGTATTCAGTGCCCGTCAGCCAACTGTGG
GCCTTCACCTCTACCTGCACTTCCCCTCTCACACCAGCTGCACTCCCGTGGCTGCCAGAGCAGGGTGGTTTTCCCCAATACCTGGAGCTC
AGAAAGGCAGAGCCATCTGGCCCTCCAGGGTGTCCCCAGCCATCAGGAGACTTGAGTTGGTATTTGGACCTGAGCCCGCACATTCCACTC
CCATTCTCCCTCCAAGAGGGGCCCAGCATTGTATTTCCCTGTGACCCCTTACTCTCCTGGCCAGAACTTGAGCCAGCTGTGGGATGTTGC
TGCAGGACAGTAAGCCCTCACCTGGGCAAACATGAAGCTCTGGCCTCCTTTCCTCAGCCCCTTGTTCTTCCCTGTCCTCCACCCTGGACC
CCAGCCGGCTGCTGGAGCCCAGAGGCCACCTTCTCCCTGCATCCTGAATGATGCTTAGTCAGAAGCCTGTGTTGGAACATCCCTCGTTTA
CGGGGCGCTGGCCTACCTCCTGAGGACCTCAGCCACAGATGAGATCACACGCATGCACGTGCACACATGTACACACACACACCTACCTGC
ACAGCACGCTGTTGAGTGTTGGTTGCTAGAGTATCTGGCTGGCTGCTGTGTGCCTGGTTTCCTCACATCCTGCCTCAGCTTCACCACCCT
GGCTTATGTGGAACACCTATCAGGGAGCAGAAAAGGGGTGCAGTACACTAAGTGAACCCAGATTCTGGATTCTTGGTGTCCACAGCCTAG
CTGATACGAGATAGCCCATAGGACACCTGGTTTAGGTAGAAGGAGCCTCCTCAAAGGCAGTGCTGGGCACCCACGGGTGTGCTGGATACT
GGAGTTTGAGAGGAGGGAGGTGCTGGGGCCAAAGGAGACACTAGAAAAGTGGTAGATGGGACAGGTAAGTGGCAGAGGTGAGGGGATAAG
TTAGAATGTAAAAGGGCAGTAATTAGGGGTGAGGGAAAGGAGATAGGGGACCCTAGGAGGTAGAGTGGGACCATGTCGTGAGGCAGTTGA
AGAGTTGAGGAAAGGTTTTTCTGGGCCCTACTGCTCCCCTCTGCTGCAGGTAAGTCAGAGCAGCTTTACCACAGCTTCAGGCCACGAGAG
CCCCTTCACCCGCCCTGCTGCGCCATAGGCAGAGGCTTATAAAGAAATGGGTTCTGGGCCAGGTGTGGTGGCTCAAGCCTGTAATCCCAG
CACTTTGGGAGGCCGAGGCGGGTGGATCACCTGAGGTTAGGAGTTCGAGATCAGCCTGGCCAACATGGTGAAACCCTGTCTACTAAAAAT
AAAAAAATTAGCTGGGCGTGGTGGTGGGCGCCTGTAATCCCAGCTACTCGGGAGGTTTAGGCAGGAGAATCGCTTGAACCCTGGAGGTGG
AGGTGGAGGTTGCAGTGAGCCGAGATCGCGCCATTGCACTCCAACCTAGGTGACAAAGCTACACGCCATCTCAAAAAAAAAAAAGAAAAA
GGGTTACAAAAGGTTCCCAGCTCCGGGGCATCAGCCTGAGTGCGCTTGAGCTGCTCCAAACCTGGCCCTTCCCCACTCCTCTAGCATCGC
CACCCGCATGGCCCTGGAACTCCCGCGGCGGCGGGGGCGGGCCCGTGCCTGCTGTGCCCCGACTTCCCACACCAGCCGCGCCCACCGCAG
GTGGGACTCAGGTTCGCCCTCTGGGCCAGGTCCTTCACGAGGAGGGAGCTACCCTTCGCCAGAAGTTTGTGAGAATGTGGCCGCCCTTTT
CCTGCCCTCTGCCCCATGTGGGTGGGGGGCCTCGTGGCCCGGCCGGCGCCCCGTCCCCTTCTGCATGTCTGAGGCCACCGGCAACCGCCG
CCCCACTCCAGATTTGCCCCCGCCTTGTTTTGAAAGCCCCTTATTTATAACTTTTATACTTTGTGCAGGTCGCGGCGCTTCCTGCCTCAT

>In-frame_ENST00000557821_ENST00000221214_TCGA-3H-AB3M-01A_PLCB2_chr15_40581473_-_MAPKBP1_chr15_42092021_length(amino acids)=2490AA_start in transcript=96_stop in transcript=7568
MASFLPFCLPVSAEILQRGTLGTMSLLNPVLLPPKVKAYLSQGERFIKWDDETTVASPVILRVDPKGYYLYWTYQSKEMEFLDITSIRDT
RFGKFAKMPKSQKLRDVFNMDFPDNSFLLKTLTVVSGPDMVDLTFHNFVSYKENVGKAWAEDVLALVKHPLTANASRSTFLDKILVKLKM
QLNSEGKIPVKNFFQMFPADRKRVEAALSACHLPKGKNDAINPEDFPEPVYKSFLMSLCPRPEIDEIFTSYHAKAKPYMTKEHLTKFINQ
KQRDSRLNSLLFPPARPDQVQGLIDKYEPSGINAQRGQLSPEGMVWFLCGPENSVLAQDKLLLHHDMTQPLNHYFINSSHNTYLTAGQFS
GLSSAEMYRQVLLSGCRCVELDCWKGKPPDEEPIITHGFTMTTDIFFKEAIEAIAESAFKTSPYPIILSFENHVDSPRQQAKMAEYCRTI
FGDMLLTEPLEKFPLKPGVPLPSPEDLRGKILIKNKKNQFSGPTSSSKDTGGEAEGSSPPSAPAVWAGEEGTELEEEEVEEEEEEESGNL
DEEEIKKMQSDEGTAGLEVTAYEEMSSLVNYIQPTKFVSFEFSAQKNRSYVISSFTELKAYDLLSKASVQFVDYNKRQMSRIYPKGTRMD
SSNYMPQMFWNAGCQMVALNFQTMDLPMQQNMAVFEFNGQSGYLLKHEFMRRPDKQFNPFSVDRIDVVVATTLSITVISGQFLSERSVRT
YVEVELFGLPGDPKRRYRTKLSPSTNSINPVWKEEPFVFEKILMPELASLRVAVMEEGNKFLGHRIIPINALNSGYHHLCLHSESNMPLT
MPALFIFLEMKDYIPGAWADLTVALANPIKFFSAHDTKSVKLKEAMGGLPEKPFPLASPVASQVNGALAPTSNGSPAARAGAREEAMKEA
AEPRTASLEELRELKGVVKLQRRHEKELRELERRGARRWEELLQRGAAQLAELGPPGVGGVGACKLGPGKGSRKKRSLPREESAGAAPGE
GPEGVDGRVRELKDRLELELLRQGEEQYECVLKRKEQHVAEQISKMMELAREKQAAELKALKETSENDTKEMKKKLETKRLERIQGMTKV
TTDKMAQERLKREINNSHIQEVVQVIKQMTENLERHQEKLEEKQAACLEQIREMEKQVTLEKVLGITVSGGRGLACDPRSGLVAYPAGCV
VVLFNPRKHKQHHILNSSRKTITALAFSPDGKYLVTGESGHMPAVRVWDVAEHSQVAELQEHKYGVACVAFSPSAKYIVSVGYQHDMIVN
VWAWKKNIVVASNKVSSRVTAVSFSEDCSYFVTAGNRHIKFWYLDDSKTSKVNATVPLLGRSGLLGELRNNLFTDVACGRGKKADSTFCI
TSSGLLCEFSDRRLLDKWVELRVYPEVKDSNQACLPPSSFITCSSDNTIRLWNTESSGVHGSTLHRNILSSDLIKIIYVDGNTQALLDTE
LPGGDKADASLLDPRVGIRSVCVSPNGQHLASGDRMGTLRVHELQSLSEMLKVEAHDSEILCLEYSKPDTGLKLLASASRDRLIHVLDAG
REYSLQQTLDEHSSSITAVKFAASDGQVRMISCGADKSIYFRTAQKSGDGVQFTRTHHVVRKTTLYDMDVEPSWKYTAIGCQDRNIRIFN
ISSGKQKKLFKGSQGEDGTLIKVQTDPSGIYIATSCSDKNLSIFDFSSGECVATMFGHSEIVTGMKFSNDCKHLISVSGDSCIFVWRLSS
EMTISMRQRLAELRQRQRGGKQQGPSSPQRASGPNRHQAPSMLSPGPALSSDSDKEGEDEGTEEELPALPVLAKSTKKALASVPSPALPR
SLSHWEMSRAQESVGFLDPAPAANPGPRRRGRWVQPGVELSVRSMLDLRQLETLAPSLQDPSQDSLAIIPSGPRKHGQEALETSLTSQNE
KPPRPQASQPCSYPHIIRLLSQEEGVFAQDLEPAPIEDGIVYPEPSDNPTMDTSEFQVQAPARGTLGRVYPGSRSSEKHSPDSACSVDYS
SSCLSSPEHPTEDSESTEPLSVDGISSDLEEPAEGDEEEEEEEGGMGPYGLQEGSPQTPDQEQFLKQHFETLASGAAPGAPVQVPERSES
RSISSRFLLQVQTRPLREPSPSSSSLALMSRPAQVPQASGEQPRGNGANPPGAPPEVEPSSGNPSPQQAASVLLPRCRLNPDSSWAPKRV
ATASPFSGLQKAQSVHSLVPQERHEASLQAPSPGALLSREIEAQDGLGSLPPADGRPSRPHSYQNPTTSSMAKISRSISVGENLGLVAEP
QAHAPIRVSPLSKLALPSRAHLVLDIPKPLPDRPTLAAFSPVTKGRAPGEAEKPGFPVGLGKAHSTTERWACLGEGTTPKPRTECQAHPG
PSSPCAQQLPVSSLFQGPENLQPPPPEKTPNPMECTKPGAALSQDSEPAVSLEQCEQLVAELRGSVRQAVRLYHSVAGCKMPSAEQSRIA

--------------------------------------------------------------
>In-frame_ENST00000557821_ENST00000457542_TCGA-3H-AB3M-01A_PLCB2_chr15_40581473_-_MAPKBP1_chr15_42092021_length(transcript)=10339nt_BP=3507nt
CAGCCAGGGCCACCCCAGGGGCTATAAGAGCAACTAGATTTCTGGAGCAGCTCGGGGATGGGTGCCATTTGAGCCCAGCTTGGCTCCCCC
TCCTGGCTGGCCTCCTTCCTGCCCTTCTGCCTGCCTGTGTCTGCTGAGATTCTGCAAAGAGGAACGCTTGGCACCATGTCTCTGCTCAAC
CCTGTCCTGCTGCCCCCCAAGGTGAAGGCCTATCTGAGCCAAGGGGAGCGCTTCATCAAATGGGATGATGAAACTACAGTTGCCTCTCCA
GTTATCCTCCGTGTGGATCCTAAGGGCTACTACTTATACTGGACGTATCAAAGTAAGGAGATGGAGTTTCTGGATATCACCAGCATCCGG
GATACTCGCTTTGGGAAGTTTGCCAAGATGCCCAAGAGCCAGAAGCTCCGGGACGTCTTCAACATGGACTTTCCTGATAACAGTTTCCTG
CTGAAGACACTCACGGTGGTGTCCGGCCCGGACATGGTGGACCTCACCTTCCACAACTTCGTCTCCTACAAGGAGAACGTGGGCAAGGCC
TGGGCTGAGGACGTACTGGCCCTAGTCAAACATCCGCTGACGGCCAACGCCTCCCGCAGCACCTTCCTGGACAAGATCCTTGTGAAGCTC
AAGATGCAGCTCAACTCTGAAGGGAAGATTCCGGTGAAGAACTTTTTCCAGATGTTTCCTGCTGACCGCAAGCGGGTGGAAGCTGCTCTC
AGTGCCTGCCACCTCCCCAAAGGCAAAAATGACGCCATCAATCCTGAGGACTTCCCAGAACCTGTCTACAAGAGTTTCCTCATGAGCCTC
TGTCCTCGGCCAGAAATAGATGAGATCTTCACTTCTTACCATGCTAAGGCCAAACCCTACATGACGAAGGAGCACCTGACCAAATTCATC
AACCAGAAACAGCGGGACTCCCGGCTTAACTCCCTGCTGTTCCCGCCAGCACGGCCTGACCAGGTGCAGGGCCTCATCGACAAGTATGAG
CCCAGTGGCATCAATGCACAGAGGGGCCAGCTGTCACCTGAAGGCATGGTCTGGTTTCTCTGTGGGCCAGAGAACAGCGTGCTGGCCCAG
GACAAGCTGCTGCTCCACCACGACATGACGCAGCCACTCAATCATTACTTCATCAACTCGTCCCACAACACCTACCTGACAGCCGGCCAG
TTCTCAGGCCTCTCCTCGGCTGAGATGTACCGCCAGGTGCTGCTCTCTGGCTGCCGTTGCGTGGAGCTAGACTGCTGGAAGGGGAAACCC
CCTGACGAGGAGCCCATTATCACCCATGGCTTCACCATGACCACAGACATCTTCTTCAAAGAAGCAATTGAGGCTATTGCAGAAAGCGCC
TTTAAGACCTCCCCCTATCCCATCATCCTGTCGTTTGAGAACCATGTGGACTCACCCCGCCAGCAGGCTAAGATGGCTGAGTATTGCCGG
ACGATCTTTGGGGATATGCTGCTCACAGAGCCCCTGGAAAAGTTCCCACTAAAACCAGGTGTCCCCCTGCCCAGCCCTGAGGATCTCAGG
GGCAAGATCCTCATCAAGAACAAGAAGAACCAGTTTTCTGGCCCCACCTCCTCCAGTAAGGATACTGGTGGGGAGGCTGAGGGCAGCAGC
CCACCCAGTGCCCCTGCAGTGTGGGCTGGCGAGGAAGGGACTGAGCTGGAGGAGGAGGAGGTGGAAGAGGAAGAGGAGGAGGAGTCAGGA
AACCTGGATGAAGAAGAGATTAAGAAGATGCAGTCGGATGAGGGCACAGCGGGCCTGGAAGTGACGGCTTATGAGGAGATGTCCAGCCTA
GTCAATTACATCCAGCCCACCAAGTTCGTCTCCTTTGAGTTCTCTGCCCAAAAGAACCGAAGTTATGTCATCTCGTCCTTCACAGAGCTC
AAGGCATATGACCTGCTCTCCAAGGCCTCGGTGCAGTTTGTGGACTACAACAAGCGCCAGATGAGCCGCATTTACCCCAAGGGAACCCGC
ATGGACTCCTCCAACTACATGCCCCAGATGTTCTGGAATGCTGGATGCCAGATGGTTGCCCTCAACTTCCAGACGATGGACTTGCCCATG
CAGCAGAACATGGCAGTATTTGAGTTCAACGGGCAGAGCGGCTACCTCCTCAAGCATGAGTTCATGCGCCGGCCGGACAAGCAGTTCAAC
CCCTTCTCAGTGGACCGCATCGACGTGGTGGTGGCCACCACCCTTTCCATTACGGTGATCTCTGGGCAGTTCCTGTCAGAACGCAGCGTG
CGCACCTATGTAGAAGTGGAGCTGTTTGGCCTTCCTGGGGACCCCAAGAGGCGCTATCGAACTAAGCTGTCACCCAGTACTAACTCCATC
AATCCTGTCTGGAAGGAGGAGCCCTTTGTCTTTGAGAAGATCTTGATGCCTGAGCTGGCCTCCCTCAGAGTGGCTGTGATGGAGGAAGGC
AACAAGTTTCTTGGACACCGCATCATCCCCATCAATGCCCTAAATTCTGGGTACCACCACCTGTGCCTGCACAGTGAGAGCAACATGCCC
CTCACCATGCCTGCGCTCTTCATCTTCCTGGAGATGAAGGACTACATACCTGGTGCTTGGGCAGATCTCACTGTGGCCCTCGCCAACCCC
ATTAAGTTCTTCAGTGCCCATGACACGAAGTCTGTGAAGCTCAAGGAGGCCATGGGAGGTCTGCCTGAGAAGCCCTTCCCACTGGCGAGT
CCAGTTGCCAGCCAGGTCAATGGGGCGTTGGCCCCAACGAGCAATGGGTCACCAGCAGCCAGGGCCGGGGCCAGGGAAGAGGCTATGAAA
GAAGCTGCGGAGCCGCGGACCGCCAGCCTGGAGGAGCTCCGGGAGCTAAAGGGCGTGGTGAAGCTGCAGCGGCGGCACGAGAAGGAGCTG
CGAGAGTTGGAGCGGCGCGGAGCGCGGCGCTGGGAGGAGCTGCTGCAGCGGGGCGCGGCGCAGCTGGCGGAGCTCGGGCCACCGGGCGTG
GGGGGCGTCGGGGCCTGCAAGCTCGGTCCCGGCAAGGGCTCTCGCAAGAAGAGGAGCCTGCCCCGCGAGGAGAGCGCCGGAGCCGCGCCG
GGCGAGGGCCCTGAGGGCGTGGACGGGCGCGTGCGGGAGCTGAAAGACAGGCTGGAGCTGGAGCTGCTGCGGCAGGGCGAGGAGCAGTAC
GAGTGCGTTCTGAAGCGCAAGGAGCAGCACGTGGCCGAGCAAATCTCCAAAATGATGGAGCTGGCCAGAGAGAAACAGGCGGCAGAGCTG
AAGGCCCTGAAGGAGACGTCGGAGAACGACACCAAAGAGATGAAGAAAAAGCTGGAGACAAAGAGACTGGAGCGGATCCAGGGCATGACC
AAAGTCACCACAGACAAGATGGCCCAGGAGAGGTTGAAGAGAGAGATTAACAACTCCCACATCCAGGAAGTAGTGCAGGTGATCAAGCAG
ATGACGGAGAACTTGGAGAGGCACCAGGAGAAGCTGGAGGAGAAGCAGGCGGCTTGCCTGGAACAGATACGGGAGATGGAAAAGCAGGTG
ACCTTGGAGAAGGTGCTGGGAATTACAGTGTCTGGAGGCAGAGGACTTGCCTGTGACCCCCGATCAGGTTTAGTTGCTTACCCAGCAGGG
TGTGTGGTTGTGTTGTTCAATCCCCGGAAACACAAACAGCACCACATCCTCAACAGTTCCAGGAAAACCATCACTGCCCTTGCCTTCTCC
CCTGATGGCAAGTACTTGGTCACTGGAGAGAGTGGGCACATGCCTGCCGTGCGGGTTTGGGACGTGGCAGAGCACAGCCAGGTGGCCGAG
CTGCAGGAGCACAAGTATGGTGTGGCTTGTGTGGCCTTCTCTCCTAGCGCCAAGTACATTGTCTCTGTGGGCTACCAGCATGACATGATC
GTCAACGTGTGGGCCTGGAAGAAAAACATTGTGGTGGCCTCCAACAAGGTGTCCAGTCGGGTGACAGCAGTGTCCTTCTCTGAGGATTGC
AGCTACTTTGTCACTGCAGGCAACCGACACATCAAATTCTGGTATCTCGATGACAGCAAGACCTCAAAGGTGAATGCCACTGTGCCCTTG
CTGGGCCGCTCAGGGCTGCTGGGAGAGCTACGGAACAACCTATTCACTGATGTGGCCTGTGGCAGAGGAAAAAAGGCGGACAGTACCTTC
TGCATCACGTCCTCAGGGCTGCTGTGCGAGTTCAGTGATCGAAGGCTTTTGGACAAGTGGGTGGAGCTGAGGACCACAGTGGCCCACTGC
ATCTCTGTGAGCCAAGACTACATCTTCTGTGGCTGTGCTGATGGCACCGTGCGCCTTTTCAACCCCTCTAACCTGCACTTCCTTAGCACC
TTGCCCCGACCCCATGCTCTGGGGACAGACATTGCTAGCGTCACCGAGGCCAGTCGCCTCTTCTCTGGAGTGGCGAATGCCAGGTATCCA
GACACCATTGCCTTGACCTTTGATCCTACTAATCAGTGGCTGTCTTGTGTGTACAACGATCATAGCATTTATGTTTGGGATGTGAGGGAC
CCCAAGAAAGTGGGCAAGGTGTACTCGGCTCTGTATCATTCTTCCTGCGTCTGGAGTGTGGAGGTCTACCCCGAGGTGAAGGATAGTAAC
CAGGCCTGCCTGCCCCCCAGTTCCTTTATTACCTGCTCCTCAGACAACACCATCCGCCTGTGGAACACAGAGAGCTCCGGGGTGCATGGC
TCCACCCTCCACCGAAACATCCTCAGCAGTGACCTCATTAAAATCATCTATGTGGATGGGAACACCCAGGCCCTGCTGGACACAGAGCTG
CCTGGAGGAGACAAAGCTGATGCATCCCTGTTGGATCCCCGCGTGGGCATCCGCTCGGTGTGTGTCAGCCCCAATGGACAGCATCTAGCA
TCAGGGGACCGTATGGGCACACTTAGGGTGCACGAACTTCAGTCCCTGAGTGAGATGCTGAAGGTGGAGGCCCATGACTCTGAGATTCTG
TGCCTGGAGTATTCTAAGCCAGACACAGGTCTGAAACTGCTAGCATCGGCGAGCCGGGACCGGCTGATCCATGTGCTGGATGCCGGGCGG
GAGTACAGCCTACAGCAGACGCTGGACGAACACTCATCCTCCATCACTGCTGTTAAGTTTGCAGCCAGTGATGGGCAAGTCCGCATGATC
AGCTGTGGAGCAGACAAGAGCATCTACTTCCGCACTGCGCAGAAGTCTGGAGATGGAGTGCAGTTCACACGGACACACCACGTGGTGCGG
AAGACGACCCTCTATGACATGGATGTGGAGCCCAGCTGGAAGTACACGGCTATCGGCTGCCAGGACCGAAATATTCGGATATTTAACATC
AGCAGTGGAAAGCAGAAGAAGCTGTTTAAAGGGTCACAGGGTGAGGACGGCACACTCATTAAGGTGCAGACAGACCCCTCAGGGATCTAC
ATTGCCACCAGCTGTTCTGACAAGAATCTCTCCATTTTTGACTTCTCCTCAGGCGAGTGCGTGGCCACCATGTTTGGCCACTCAGAGATT
GTCACTGGCATGAAATTTAGTAATGATTGTAAACATCTCATCTCTGTGTCTGGGGACAGCTGCATATTTGTGTGGCGCCTGAGCTCTGAG
ATGACCATCAGCATGAGGCAGCGTCTGGCCGAGTTGCGCCAGCGTCAGCGGGGCGGCAAGCAGCAAGGACCATCCTCTCCCCAAAGGGCT
TCTGGACCCAACCGGCACCAGGCCCCATCAATGCTGTCTCCTGGACCGGCTCTCTCATCAGACAGTGACAAGGAGGGAGAAGATGAGGGG
ACTGAAGAAGAACTTCCAGCACTGCCCGTCCTTGCCAAGAGTACCAAGAAGGCACTGGCCTCGGTCCCCAGCCCAGCTTTGCCCCGAAGC
CTGTCCCACTGGGAGATGAGTCGGGCACAGGAGTCCGTGGGGTTCCTGGACCCAGCTCCTGCAGCCAACCCAGGACCCAGAAGAAGAGGG
CGCTGGGTTCAGCCAGGTGTGGAACTGAGCGTTAGATCCATGCTGGATCTGCGGCAGCTGGAAACACTGGCCCCAAGCCTGCAGGACCCT
AGCCAGGACTCGCTGGCCATCATCCCATCTGGTCCCAGGAAGCATGGGCAGGAGGCCCTTGAGACTTCACTCACTAGCCAGAATGAAAAG
CCCCCTCGGCCTCAGGCTTCCCAACCTTGTTCCTATCCCCATATTATCCGATTATTGTCACAAGAGGAAGGGGTCTTTGCCCAAGATCTG
GAACCTGCACCCATTGAAGATGGTATTGTCTACCCGGAGCCGAGTGACAACCCCACCATGGATACCAGTGAGTTCCAAGTGCAGGCTCCA
GCCCGGGGAACTCTGGGAAGAGTGTACCCAGGCAGCAGGAGCTCAGAAAAGCACAGCCCTGACAGTGCCTGCTCTGTGGATTACAGCAGC
AGCTGCCTTTCCAGCCCGGAGCACCCCACTGAAGACTCTGAGAGCACGGAGCCCCTCAGTGTGGATGGCATCTCCTCAGACCTTGAAGAG
CCAGCTGAGGGTGATGAAGAAGAGGAAGAAGAGGAGGGAGGCATGGGCCCCTATGGGCTACAGGAGGGCAGCCCCCAGACTCCAGACCAG
GAGCAGTTTCTAAAACAGCACTTTGAGACTCTGGCCAGTGGAGCTGCTCCAGGGGCCCCAGTGCAGGTCCCAGAGAGGTCAGAGTCTCGG
AGTATCTCTTCACGATTCCTGTTGCAAGTACAGACCCGCCCACTCAGGGAACCATCCCCATCCTCCTCAAGCCTGGCACTGATGTCGAGA
CCAGCCCAGGTGCCACAGGCATCTGGTGAGCAGCCGAGAGGCAATGGTGCCAATCCCCCTGGAGCACCCCCGGAGGTGGAACCGTCCTCT
GGCAACCCCAGCCCCCAGCAGGCAGCCTCTGTGCTGTTGCCACGATGCCGTCTCAACCCTGACAGCAGCTGGGCTCCCAAGAGAGTGGCC
ACAGCCAGCCCCTTTTCTGGACTCCAGAAGGCCCAGTCTGTGCACAGTCTGGTGCCACAGGAAAGACATGAGGCCAGTCTGCAGGCCCCT
TCACCAGGCGCACTGCTGTCTCGGGAGATCGAAGCTCAGGATGGTCTGGGCTCCCTGCCCCCAGCTGATGGCCGTCCGTCTCGGCCTCAC
TCCTATCAGAACCCCACCACCAGTTCCATGGCCAAGATATCCCGCAGTATCTCTGTTGGGGAGAACCTGGGCCTGGTGGCTGAACCTCAA
GCTCATGCCCCCATCCGAGTCTCACCACTCAGCAAGCTGGCCCTGCCCAGCCGGGCTCACCTGGTCCTGGACATCCCCAAACCACTGCCT
GACCGTCCTACCCTGGCTGCATTCTCTCCTGTCACCAAAGGCCGGGCCCCTGGCGAGGCAGAAAAGCCTGGCTTCCCGGTGGGCCTAGGA
AAAGCTCACAGTACAACTGAGAGATGGGCCTGTTTGGGGGAGGGCACCACTCCCAAGCCTAGGACAGAGTGCCAGGCTCATCCTGGGCCC
AGCAGCCCCTGTGCCCAGCAACTGCCAGTCAGCAGCCTCTTCCAAGGCCCTGAAAACTTGCAGCCCCCACCCCCTGAGAAGACTCCCAAC
CCCATGGAATGCACCAAGCCAGGGGCAGCCCTGAGCCAGGACTCAGAGCCAGCGGTGAGCCTGGAGCAGTGTGAGCAGCTGGTGGCAGAG
CTCCGCGGCAGCGTGCGCCAGGCAGTGCGGCTCTACCACTCGGTGGCTGGCTGCAAGATGCCCTCAGCAGAGCAAAGTCGGATTGCCCAG
CTCCTCAGAGACACCTTCTCTTCAGTGCGACAGGAGCTGGAAGCTGTGGCTGGGGCAGTGCTGTCCAGCCCAGGCAGCAGCCCTGGGGCT
GTGGGAGCCGAGCAGACACAGGCCCTGCTGGAGCAATACTCAGAACTGTTGCTTCGAGCCGTGGAACGGCGTATGGAACGCAAACTCTGA
GTTCTGGAAGCCTGTCCCAAGTGAATGAATGCTCCAGCGATTCCAAACTGCAGCCCCTCTGCCCCTCACCAAAACCTGCGGGGCTGCTTG
GAGTGGAAAGCAGGGAGCAGTGTTCAGAGGCAAAGCAGCCTTCCCAGCCGCTCCTCGTGGGGGGCCTGTATTTATTAATTTATTTCCCTG
ACTGTTGCCTCACTTCCTTGGAACTCCTGCCTCCACAGCCCCTCCAGTGGCAGGGACAGGTCTTGGGTCTTTGTCATCTTGGTGCTGTGA
GAGGTAGGAGGGCAGCCTGCCCCATCTAGGAATCTGGGAAGGGCTGGCCCTCTCTTAGAAGCCATTTGAAATTACTGCAGGGATTAGCTC
CCTGTGGTGGAGCATACACAGGGTACTCTGGGGTCGAGGTGAGAGGTGATGTGGTATTCAGTGCCCGTCAGCCAACTGTGGGCCTTCACC
TCTACCTGCACTTCCCCTCTCACACCAGCTGCACTCCCGTGGCTGCCAGAGCAGGGTGGTTTTCCCCAATACCTGGAGCTCAGAAAGGCA
GAGCCATCTGGCCCTCCAGGGTGTCCCCAGCCATCAGGAGACTTGAGTTGGTATTTGGACCTGAGCCCGCACATTCCACTCCCATTCTCC
CTCCAAGAGGGGCCCAGCATTGTATTTCCCTGTGACCCCTTACTCTCCTGGCCAGAACTTGAGCCAGCTGTGGGATGTTGCTGCAGGACA
GTAAGCCCTCACCTGGGCAAACATGAAGCTCTGGCCTCCTTTCCTCAGCCCCTTGTTCTTCCCTGTCCTCCACCCTGGACCCCAGCCGGC
TGCTGGAGCCCAGAGGCCACCTTCTCCCTGCATCCTGAATGATGCTTAGTCAGAAGCCTGTGTTGGAACATCCCTCGTTTACGGGGCGCT
GGCCTACCTCCTGAGGACCTCAGCCACAGATGAGATCACACGCATGCACGTGCACACATGTACACACACACACCTACCTGCACAGCACGC
TGTTGAGTGTTGGTTGCTAGAGTATCTGGCTGGCTGCTGTGTGCCTGGTTTCCTCACATCCTGCCTCAGCTTCACCACCCTGGCTTATGT
GGAACACCTATCAGGGAGCAGAAAAGGGGTGCAGTACACTAAGTGAACCCAGATTCTGGATTCTTGGTGTCCACAGCCTAGCTGATACGA
GATAGCCCATAGGACACCTGGTTTAGGTAGAAGGAGCCTCCTCAAAGGCAGTGCTGGGCACCCACGGGTGTGCTGGATACTGGAGTTTGA
GAGGAGGGAGGTGCTGGGGCCAAAGGAGACACTAGAAAAGTGGTAGATGGGACAGGTAAGTGGCAGAGGTGAGGGGATAAGTTAGAATGT
AAAAGGGCAGTAATTAGGGGTGAGGGAAAGGAGATAGGGGACCCTAGGAGGTAGAGTGGGACCATGTCGTGAGGCAGTTGAAGAGTTGAG
GAAAGGTTTTTCTGGGCCCTACTGCTCCCCTCTGCTGCAGGTAAGTCAGAGCAGCTTTACCACAGCTTCAGGCCACGAGAGCCCCTTCAC
CCGCCCTGCTGCGCCATAGGCAGAGGCTTATAAAGAAATGGGTTCTGGGCCAGGTGTGGTGGCTCAAGCCTGTAATCCCAGCACTTTGGG
AGGCCGAGGCGGGTGGATCACCTGAGGTTAGGAGTTCGAGATCAGCCTGGCCAACATGGTGAAACCCTGTCTACTAAAAATAAAAAAATT
AGCTGGGCGTGGTGGTGGGCGCCTGTAATCCCAGCTACTCGGGAGGTTTAGGCAGGAGAATCGCTTGAACCCTGGAGGTGGAGGTGGAGG
TTGCAGTGAGCCGAGATCGCGCCATTGCACTCCAACCTAGGTGACAAAGCTACACGCCATCTCAAAAAAAAAAAAGAAAAAGGGTTACAA
AAGGTTCCCAGCTCCGGGGCATCAGCCTGAGTGCGCTTGAGCTGCTCCAAACCTGGCCCTTCCCCACTCCTCTAGCATCGCCACCCGCAT
GGCCCTGGAACTCCCGCGGCGGCGGGGGCGGGCCCGTGCCTGCTGTGCCCCGACTTCCCACACCAGCCGCGCCCACCGCAGGTGGGACTC
AGGTTCGCCCTCTGGGCCAGGTCCTTCACGAGGAGGGAGCTACCCTTCGCCAGAAGTTTGTGAGAATGTGGCCGCCCTTTTCCTGCCCTC
TGCCCCATGTGGGTGGGGGGCCTCGTGGCCCGGCCGGCGCCCCGTCCCCTTCTGCATGTCTGAGGCCACCGGCAACCGCCGCCCCACTCC
AGATTTGCCCCCGCCTTGTTTTGAAAGCCCCTTATTTATAACTTTTATACTTTGTGCAGGTCGCGGCGCTTCCTGCCTCATCCTCGGCTG

>In-frame_ENST00000557821_ENST00000457542_TCGA-3H-AB3M-01A_PLCB2_chr15_40581473_-_MAPKBP1_chr15_42092021_length(amino acids)=2607AA_start in transcript=96_stop in transcript=7919
MASFLPFCLPVSAEILQRGTLGTMSLLNPVLLPPKVKAYLSQGERFIKWDDETTVASPVILRVDPKGYYLYWTYQSKEMEFLDITSIRDT
RFGKFAKMPKSQKLRDVFNMDFPDNSFLLKTLTVVSGPDMVDLTFHNFVSYKENVGKAWAEDVLALVKHPLTANASRSTFLDKILVKLKM
QLNSEGKIPVKNFFQMFPADRKRVEAALSACHLPKGKNDAINPEDFPEPVYKSFLMSLCPRPEIDEIFTSYHAKAKPYMTKEHLTKFINQ
KQRDSRLNSLLFPPARPDQVQGLIDKYEPSGINAQRGQLSPEGMVWFLCGPENSVLAQDKLLLHHDMTQPLNHYFINSSHNTYLTAGQFS
GLSSAEMYRQVLLSGCRCVELDCWKGKPPDEEPIITHGFTMTTDIFFKEAIEAIAESAFKTSPYPIILSFENHVDSPRQQAKMAEYCRTI
FGDMLLTEPLEKFPLKPGVPLPSPEDLRGKILIKNKKNQFSGPTSSSKDTGGEAEGSSPPSAPAVWAGEEGTELEEEEVEEEEEEESGNL
DEEEIKKMQSDEGTAGLEVTAYEEMSSLVNYIQPTKFVSFEFSAQKNRSYVISSFTELKAYDLLSKASVQFVDYNKRQMSRIYPKGTRMD
SSNYMPQMFWNAGCQMVALNFQTMDLPMQQNMAVFEFNGQSGYLLKHEFMRRPDKQFNPFSVDRIDVVVATTLSITVISGQFLSERSVRT
YVEVELFGLPGDPKRRYRTKLSPSTNSINPVWKEEPFVFEKILMPELASLRVAVMEEGNKFLGHRIIPINALNSGYHHLCLHSESNMPLT
MPALFIFLEMKDYIPGAWADLTVALANPIKFFSAHDTKSVKLKEAMGGLPEKPFPLASPVASQVNGALAPTSNGSPAARAGAREEAMKEA
AEPRTASLEELRELKGVVKLQRRHEKELRELERRGARRWEELLQRGAAQLAELGPPGVGGVGACKLGPGKGSRKKRSLPREESAGAAPGE
GPEGVDGRVRELKDRLELELLRQGEEQYECVLKRKEQHVAEQISKMMELAREKQAAELKALKETSENDTKEMKKKLETKRLERIQGMTKV
TTDKMAQERLKREINNSHIQEVVQVIKQMTENLERHQEKLEEKQAACLEQIREMEKQVTLEKVLGITVSGGRGLACDPRSGLVAYPAGCV
VVLFNPRKHKQHHILNSSRKTITALAFSPDGKYLVTGESGHMPAVRVWDVAEHSQVAELQEHKYGVACVAFSPSAKYIVSVGYQHDMIVN
VWAWKKNIVVASNKVSSRVTAVSFSEDCSYFVTAGNRHIKFWYLDDSKTSKVNATVPLLGRSGLLGELRNNLFTDVACGRGKKADSTFCI
TSSGLLCEFSDRRLLDKWVELRTTVAHCISVSQDYIFCGCADGTVRLFNPSNLHFLSTLPRPHALGTDIASVTEASRLFSGVANARYPDT
IALTFDPTNQWLSCVYNDHSIYVWDVRDPKKVGKVYSALYHSSCVWSVEVYPEVKDSNQACLPPSSFITCSSDNTIRLWNTESSGVHGST
LHRNILSSDLIKIIYVDGNTQALLDTELPGGDKADASLLDPRVGIRSVCVSPNGQHLASGDRMGTLRVHELQSLSEMLKVEAHDSEILCL
EYSKPDTGLKLLASASRDRLIHVLDAGREYSLQQTLDEHSSSITAVKFAASDGQVRMISCGADKSIYFRTAQKSGDGVQFTRTHHVVRKT
TLYDMDVEPSWKYTAIGCQDRNIRIFNISSGKQKKLFKGSQGEDGTLIKVQTDPSGIYIATSCSDKNLSIFDFSSGECVATMFGHSEIVT
GMKFSNDCKHLISVSGDSCIFVWRLSSEMTISMRQRLAELRQRQRGGKQQGPSSPQRASGPNRHQAPSMLSPGPALSSDSDKEGEDEGTE
EELPALPVLAKSTKKALASVPSPALPRSLSHWEMSRAQESVGFLDPAPAANPGPRRRGRWVQPGVELSVRSMLDLRQLETLAPSLQDPSQ
DSLAIIPSGPRKHGQEALETSLTSQNEKPPRPQASQPCSYPHIIRLLSQEEGVFAQDLEPAPIEDGIVYPEPSDNPTMDTSEFQVQAPAR
GTLGRVYPGSRSSEKHSPDSACSVDYSSSCLSSPEHPTEDSESTEPLSVDGISSDLEEPAEGDEEEEEEEGGMGPYGLQEGSPQTPDQEQ
FLKQHFETLASGAAPGAPVQVPERSESRSISSRFLLQVQTRPLREPSPSSSSLALMSRPAQVPQASGEQPRGNGANPPGAPPEVEPSSGN
PSPQQAASVLLPRCRLNPDSSWAPKRVATASPFSGLQKAQSVHSLVPQERHEASLQAPSPGALLSREIEAQDGLGSLPPADGRPSRPHSY
QNPTTSSMAKISRSISVGENLGLVAEPQAHAPIRVSPLSKLALPSRAHLVLDIPKPLPDRPTLAAFSPVTKGRAPGEAEKPGFPVGLGKA
HSTTERWACLGEGTTPKPRTECQAHPGPSSPCAQQLPVSSLFQGPENLQPPPPEKTPNPMECTKPGAALSQDSEPAVSLEQCEQLVAELR

--------------------------------------------------------------
>In-frame_ENST00000456256_ENST00000221214_TCGA-3H-AB3M-01A_PLCB2_chr15_40581473_-_MAPKBP1_chr15_42092021_length(transcript)=9941nt_BP=3462nt
CCCCAGGGGCTATAAGAGCAACTAGATTTCTGGAGCAGCTCGGGGATGGGTGCCATTTGAGCCCAGCTTGGCTCCCCCTCCTGGCTGGCC
TCCTTCCTGCCCTTCTGCCTGCCTGTGTCTGCTGAGATTCTGCAAAGAGGAACGCTTGGCACCATGTCTCTGCTCAACCCTGTCCTGCTG
CCCCCCAAGGTGAAGGCCTATCTGAGCCAAGGGGAGCGCTTCATCAAATGGGATGATGAAACTACAGTTGCCTCTCCAGTTATCCTCCGT
GTGGATCCTAAGGGCTACTACTTATACTGGACGTATCAAAGTAAGGAGATGGAGTTTCTGGATATCACCAGCATCCGGGATACTCGCTTT
GGGAAGTTTGCCAAGATGCCCAAGAGCCAGAAGCTCCGGGACGTCTTCAACATGGACTTTCCTGATAACAGTTTCCTGCTGAAGACACTC
ACGGTGGTGTCCGGCCCGGACATGGTGGACCTCACCTTCCACAACTTCGTCTCCTACAAGGAGAACGTGGGCAAGGCCTGGGCTGAGGAC
GTACTGGCCCTAGTCAAACATCCGCTGACGGCCAACGCCTCCCGCAGCACCTTCCTGGACAAGATCCTTGTGAAGCTCAAGATGCAGCTC
AACTCTGAAGGGAAGATTCCGGTGAAGAACTTTTTCCAGATGTTTCCTGCTGACCGCAAGCGGGTGGAAGCTGCTCTCAGTGCCTGCCAC
CTCCCCAAAGGCAAAAATGACGCCATCAATCCTGAGGACTTCCCAGAACCTGTCTACAAGAGTTTCCTCATGAGCCTCTGTCCTCGGCCA
GAAATAGATGAGATCTTCACTTCTTACCATGCTAAGGCCAAACCCTACATGACGAAGGAGCACCTGACCAAATTCATCAACCAGAAACAG
CGGGACTCCCGGCTTAACTCCCTGCTGTTCCCGCCAGCACGGCCTGACCAGGTGCAGGGCCTCATCGACAAGTATGAGCCCAGTGGCATC
AATGCACAGAGGGGCCAGCTGTCACCTGAAGGCATGGTCTGGTTTCTCTGTGGGCCAGAGAACAGCGTGCTGGCCCAGGACAAGCTGCTG
CTCCACCACGACATGACGCAGCCACTCAATCATTACTTCATCAACTCGTCCCACAACACCTACCTGACAGCCGGCCAGTTCTCAGGCCTC
TCCTCGGCTGAGATGTACCGCCAGGTGCTGCTCTCTGGCTGCCGTTGCGTGGAGCTAGACTGCTGGAAGGGGAAACCCCCTGACGAGGAG
CCCATTATCACCCATGGCTTCACCATGACCACAGACATCTTCTTCAAAGAAGCAATTGAGGCTATTGCAGAAAGCGCCTTTAAGACCTCC
CCCTATCCCATCATCCTGTCGTTTGAGAACCATGTGGACTCACCCCGCCAGCAGGCTAAGATGGCTGAGTATTGCCGGACGATCTTTGGG
GATATGCTGCTCACAGAGCCCCTGGAAAAGTTCCCACTAAAACCAGGTGTCCCCCTGCCCAGCCCTGAGGATCTCAGGGGCAAGATCCTC
ATCAAGAACAAGAAGAACCAGTTTTCTGGCCCCACCTCCTCCAGTAAGGATACTGGTGGGGAGGCTGAGGGCAGCAGCCCACCCAGTGCC
CCTGCAGGTGAGGGCACAGTGTGGGCTGGCGAGGAAGGGACTGAGCTGGAGGAGGAGGAGGTGGAAGAGGAAGAGGAGGAGGAGTCAGGA
AACCTGGATGAAGAAGAGATTAAGAAGATGCAGTCGGATGAGGGCACAGCGGGCCTGGAAGTGACGGCTTATGAGGAGATGTCCAGCCTA
GTCAATTACATCCAGCCCACCAAGTTCGTCTCCTTTGAGTTCTCTGCCCAAAAGAACCGAAGTTATGTCATCTCGTCCTTCACAGAGCTC
AAGGCATATGACCTGCTCTCCAAGGCCTCGGTGCAGTTTGTGGACTACAACAAGCGCCAGATGAGCCGCATTTACCCCAAGGGAACCCGC
ATGGACTCCTCCAACTACATGCCCCAGATGTTCTGGAATGCTGGATGCCAGATGGTTGCCCTCAACTTCCAGACGATGGACTTGCCCATG
CAGCAGAACATGGCAGTATTTGAGTTCAACGGGCAGAGCGGCTACCTCCTCAAGCATGAGTTCATGCGCCGGCCGGACAAGCAGTTCAAC
CCCTTCTCAGTGGACCGCATCGACGTGGTGGTGGCCACCACCCTTTCCATTACGGTGATCTCTGGGCAGTTCCTGTCAGAACGCAGCGTG
CGCACCTATGTAGAAGTGGAGCTGTTTGGCCTTCCTGGGGACCCCAAGAGGCGCTATCGAACTAAGCTGTCACCCAGTACTAACTCCATC
AATCCTGTCTGGAAGGAGGAGCCCTTTGTCTTTGAGAAGATCTTGATGCCTGAGCTGGCCTCCCTCAGAGTGGCTGTGATGGAGGAAGGC
AACAAGTTTCTTGGACACCGCATCATCCCCATCAATGCCCTAAATTCTGGGTACCACCACCTGTGCCTGCACAGTGAGAGCAACATGCCC
CTCACCATGCCTGCGCTCTTCATCTTCCTGGAGATGAAGGACTACATACCTGGTGCTTGGGCAGATCTCACTGTGGCCCTCGCCAACCCC
ATTAAGTTCTTCAGTGCCCATGACACGAAGTCTGTGAAGCTCAAGGAGGCCATGGGAGGTCTGCCTGAGAAGCCCTTCCCACTGGCGAGT
CCAGTTGCCAGCCAGGTCAATGGGGCGTTGGCCCCAACGAGCAATGGGTCACCAGAGCCGCGGACCGCCAGCCTGGAGGAGCTCCGGGAG
CTAAAGGGCGTGGTGAAGCTGCAGCGGCGGCACGAGAAGGAGCTGCGAGAGTTGGAGCGGCGCGGAGCGCGGCGCTGGGAGGAGCTGCTG
CAGCGGGGCGCGGCGCAGCTGGCGGAGCTCGGGCCACCGGGCGTGGGGGGCGTCGGGGCCTGCAAGCTCGGTCCCGGCAAGGGCTCTCGC
AAGAAGAGGAGCCTGCCCCGCGAGGAGAGCGCCGGAGCCGCGCCGGGCGAGGGCCCTGAGGGCGTGGACGGGCGCGTGCGGGAGCTGAAA
GACAGGCTGGAGCTGGAGCTGCTGCGGCAGGGCGAGGAGCAGTACGAGTGCGTTCTGAAGCGCAAGGAGCAGCACGTGGCCGAGCAAATC
TCCAAAATGATGGAGCTGGCCAGAGAGAAACAGGCGGCAGAGCTGAAGGCCCTGAAGGAGACGTCGGAGAACGACACCAAAGAGATGAAG
AAAAAGCTGGAGACAAAGAGACTGGAGCGGATCCAGGGCATGACCAAAGTCACCACAGACAAGATGGCCCAGGAGAGGTTGAAGAGAGAG
ATTAACAACTCCCACATCCAGGAAGTAGTGCAGGTGATCAAGCAGATGACGGAGAACTTGGAGAGGCACCAGGAGAAGCTGGAGGAGAAG
CAGGCGGCTTGCCTGGAACAGATACGGGAGATGGAAAAGCAGGTGACCTTGGAGAAGGTGCTGGGAATTACAGTGTCTGGAGGCAGAGGA
CTTGCCTGTGACCCCCGATCAGGTTTAGTTGCTTACCCAGCAGGGTGTGTGGTTGTGTTGTTCAATCCCCGGAAACACAAACAGCACCAC
ATCCTCAACAGTTCCAGGAAAACCATCACTGCCCTTGCCTTCTCCCCTGATGGCAAGTACTTGGTCACTGGAGAGAGTGGGCACATGCCT
GCCGTGCGGGTTTGGGACGTGGCAGAGCACAGCCAGGTGGCCGAGCTGCAGGAGCACAAGTATGGTGTGGCTTGTGTGGCCTTCTCTCCT
AGCGCCAAGTACATTGTCTCTGTGGGCTACCAGCATGACATGATCGTCAACGTGTGGGCCTGGAAGAAAAACATTGTGGTGGCCTCCAAC
AAGGTGTCCAGTCGGGTGACAGCAGTGTCCTTCTCTGAGGATTGCAGCTACTTTGTCACTGCAGGCAACCGACACATCAAATTCTGGTAT
CTCGATGACAGCAAGACCTCAAAGGTGAATGCCACTGTGCCCTTGCTGGGCCGCTCAGGGCTGCTGGGAGAGCTACGGAACAACCTATTC
ACTGATGTGGCCTGTGGCAGAGGAAAAAAGGCGGACAGTACCTTCTGCATCACGTCCTCAGGGCTGCTGTGCGAGTTCAGTGATCGAAGG
CTTTTGGACAAGTGGGTGGAGCTGAGGGTCTACCCCGAGGTGAAGGATAGTAACCAGGCCTGCCTGCCCCCCAGTTCCTTTATTACCTGC
TCCTCAGACAACACCATCCGCCTGTGGAACACAGAGAGCTCCGGGGTGCATGGCTCCACCCTCCACCGAAACATCCTCAGCAGTGACCTC
ATTAAAATCATCTATGTGGATGGGAACACCCAGGCCCTGCTGGACACAGAGCTGCCTGGAGGAGACAAAGCTGATGCATCCCTGTTGGAT
CCCCGCGTGGGCATCCGCTCGGTGTGTGTCAGCCCCAATGGACAGCATCTAGCATCAGGGGACCGTATGGGCACACTTAGGGTGCACGAA
CTTCAGTCCCTGAGTGAGATGCTGAAGGTGGAGGCCCATGACTCTGAGATTCTGTGCCTGGAGTATTCTAAGCCAGACACAGGTCTGAAA
CTGCTAGCATCGGCGAGCCGGGACCGGCTGATCCATGTGCTGGATGCCGGGCGGGAGTACAGCCTACAGCAGACGCTGGACGAACACTCA
TCCTCCATCACTGCTGTTAAGTTTGCAGCCAGTGATGGGCAAGTCCGCATGATCAGCTGTGGAGCAGACAAGAGCATCTACTTCCGCACT
GCGCAGAAGTCTGGAGATGGAGTGCAGTTCACACGGACACACCACGTGGTGCGGAAGACGACCCTCTATGACATGGATGTGGAGCCCAGC
TGGAAGTACACGGCTATCGGCTGCCAGGACCGAAATATTCGGATATTTAACATCAGCAGTGGAAAGCAGAAGAAGCTGTTTAAAGGGTCA
CAGGGTGAGGACGGCACACTCATTAAGGTGCAGACAGACCCCTCAGGGATCTACATTGCCACCAGCTGTTCTGACAAGAATCTCTCCATT
TTTGACTTCTCCTCAGGCGAGTGCGTGGCCACCATGTTTGGCCACTCAGAGATTGTCACTGGCATGAAATTTAGTAATGATTGTAAACAT
CTCATCTCTGTGTCTGGGGACAGCTGCATATTTGTGTGGCGCCTGAGCTCTGAGATGACCATCAGCATGAGGCAGCGTCTGGCCGAGTTG
CGCCAGCGTCAGCGGGGCGGCAAGCAGCAAGGACCATCCTCTCCCCAAAGGGCTTCTGGACCCAACCGGCACCAGGCCCCATCAATGCTG
TCTCCTGGACCGGCTCTCTCATCAGACAGTGACAAGGAGGGAGAAGATGAGGGGACTGAAGAAGAACTTCCAGCACTGCCCGTCCTTGCC
AAGAGTACCAAGAAGGCACTGGCCTCGGTCCCCAGCCCAGCTTTGCCCCGAAGCCTGTCCCACTGGGAGATGAGTCGGGCACAGGAGTCC
GTGGGGTTCCTGGACCCAGCTCCTGCAGCCAACCCAGGACCCAGAAGAAGAGGGCGCTGGGTTCAGCCAGGTGTGGAACTGAGCGTTAGA
TCCATGCTGGATCTGCGGCAGCTGGAAACACTGGCCCCAAGCCTGCAGGACCCTAGCCAGGACTCGCTGGCCATCATCCCATCTGGTCCC
AGGAAGCATGGGCAGGAGGCCCTTGAGACTTCACTCACTAGCCAGAATGAAAAGCCCCCTCGGCCTCAGGCTTCCCAACCTTGTTCCTAT
CCCCATATTATCCGATTATTGTCACAAGAGGAAGGGGTCTTTGCCCAAGATCTGGAACCTGCACCCATTGAAGATGGTATTGTCTACCCG
GAGCCGAGTGACAACCCCACCATGGATACCAGTGAGTTCCAAGTGCAGGCTCCAGCCCGGGGAACTCTGGGAAGAGTGTACCCAGGCAGC
AGGAGCTCAGAAAAGCACAGCCCTGACAGTGCCTGCTCTGTGGATTACAGCAGCAGCTGCCTTTCCAGCCCGGAGCACCCCACTGAAGAC
TCTGAGAGCACGGAGCCCCTCAGTGTGGATGGCATCTCCTCAGACCTTGAAGAGCCAGCTGAGGGTGATGAAGAAGAGGAAGAAGAGGAG
GGAGGCATGGGCCCCTATGGGCTACAGGAGGGCAGCCCCCAGACTCCAGACCAGGAGCAGTTTCTAAAACAGCACTTTGAGACTCTGGCC
AGTGGAGCTGCTCCAGGGGCCCCAGTGCAGGTCCCAGAGAGGTCAGAGTCTCGGAGTATCTCTTCACGATTCCTGTTGCAAGTACAGACC
CGCCCACTCAGGGAACCATCCCCATCCTCCTCAAGCCTGGCACTGATGTCGAGACCAGCCCAGGTGCCACAGGCATCTGGTGAGCAGCCG
AGAGGCAATGGTGCCAATCCCCCTGGAGCACCCCCGGAGGTGGAACCGTCCTCTGGCAACCCCAGCCCCCAGCAGGCAGCCTCTGTGCTG
TTGCCACGATGCCGTCTCAACCCTGACAGCAGCTGGGCTCCCAAGAGAGTGGCCACAGCCAGCCCCTTTTCTGGACTCCAGAAGGCCCAG
TCTGTGCACAGTCTGGTGCCACAGGAAAGACATGAGGCCAGTCTGCAGGCCCCTTCACCAGGCGCACTGCTGTCTCGGGAGATCGAAGCT
CAGGATGGTCTGGGCTCCCTGCCCCCAGCTGATGGCCGTCCGTCTCGGCCTCACTCCTATCAGAACCCCACCACCAGTTCCATGGCCAAG
ATATCCCGCAGTATCTCTGTTGGGGAGAACCTGGGCCTGGTGGCTGAACCTCAAGCTCATGCCCCCATCCGAGTCTCACCACTCAGCAAG
CTGGCCCTGCCCAGCCGGGCTCACCTGGTCCTGGACATCCCCAAACCACTGCCTGACCGTCCTACCCTGGCTGCATTCTCTCCTGTCACC
AAAGGCCGGGCCCCTGGCGAGGCAGAAAAGCCTGGCTTCCCGGTGGGCCTAGGAAAAGCTCACAGTACAACTGAGAGATGGGCCTGTTTG
GGGGAGGGCACCACTCCCAAGCCTAGGACAGAGTGCCAGGCTCATCCTGGGCCCAGCAGCCCCTGTGCCCAGCAACTGCCAGTCAGCAGC
CTCTTCCAAGGCCCTGAAAACTTGCAGCCCCCACCCCCTGAGAAGACTCCCAACCCCATGGAATGCACCAAGCCAGGGGCAGCCCTGAGC
CAGGACTCAGAGCCAGCGGTGAGCCTGGAGCAGTGTGAGCAGCTGGTGGCAGAGCTCCGCGGCAGCGTGCGCCAGGCAGTGCGGCTCTAC
CACTCGGTGGCTGGCTGCAAGATGCCCTCAGCAGAGCAAAGTCGGATTGCCCAGCTCCTCAGAGACACCTTCTCTTCAGTGCGACAGGAG
CTGGAAGCTGTGGCTGGGGCAGTGCTGTCCAGCCCAGGCAGCAGCCCTGGGGCTGTGGGAGCCGAGCAGACACAGGCCCTGCTGGAGCAA
TACTCAGAACTGTTGCTTCGAGCCGTGGAACGGCGTATGGAACGCAAACTCTGAGTTCTGGAAGCCTGTCCCAAGTGAATGAATGCTCCA
GCGATTCCAAACTGCAGCCCCTCTGCCCCTCACCAAAACCTGCGGGGCTGCTTGGAGTGGAAAGCAGGGAGCAGTGTTCAGAGGCAAAGC
AGCCTTCCCAGCCGCTCCTCGTGGGGGGCCTGTATTTATTAATTTATTTCCCTGACTGTTGCCTCACTTCCTTGGAACTCCTGCCTCCAC
AGCCCCTCCAGTGGCAGGGACAGGTCTTGGGTCTTTGTCATCTTGGTGCTGTGAGAGGTAGGAGGGCAGCCTGCCCCATCTAGGAATCTG
GGAAGGGCTGGCCCTCTCTTAGAAGCCATTTGAAATTACTGCAGGGATTAGCTCCCTGTGGTGGAGCATACACAGGGTACTCTGGGGTCG
AGGTGAGAGGTGATGTGGTATTCAGTGCCCGTCAGCCAACTGTGGGCCTTCACCTCTACCTGCACTTCCCCTCTCACACCAGCTGCACTC
CCGTGGCTGCCAGAGCAGGGTGGTTTTCCCCAATACCTGGAGCTCAGAAAGGCAGAGCCATCTGGCCCTCCAGGGTGTCCCCAGCCATCA
GGAGACTTGAGTTGGTATTTGGACCTGAGCCCGCACATTCCACTCCCATTCTCCCTCCAAGAGGGGCCCAGCATTGTATTTCCCTGTGAC
CCCTTACTCTCCTGGCCAGAACTTGAGCCAGCTGTGGGATGTTGCTGCAGGACAGTAAGCCCTCACCTGGGCAAACATGAAGCTCTGGCC
TCCTTTCCTCAGCCCCTTGTTCTTCCCTGTCCTCCACCCTGGACCCCAGCCGGCTGCTGGAGCCCAGAGGCCACCTTCTCCCTGCATCCT
GAATGATGCTTAGTCAGAAGCCTGTGTTGGAACATCCCTCGTTTACGGGGCGCTGGCCTACCTCCTGAGGACCTCAGCCACAGATGAGAT
CACACGCATGCACGTGCACACATGTACACACACACACCTACCTGCACAGCACGCTGTTGAGTGTTGGTTGCTAGAGTATCTGGCTGGCTG
CTGTGTGCCTGGTTTCCTCACATCCTGCCTCAGCTTCACCACCCTGGCTTATGTGGAACACCTATCAGGGAGCAGAAAAGGGGTGCAGTA
CACTAAGTGAACCCAGATTCTGGATTCTTGGTGTCCACAGCCTAGCTGATACGAGATAGCCCATAGGACACCTGGTTTAGGTAGAAGGAG
CCTCCTCAAAGGCAGTGCTGGGCACCCACGGGTGTGCTGGATACTGGAGTTTGAGAGGAGGGAGGTGCTGGGGCCAAAGGAGACACTAGA
AAAGTGGTAGATGGGACAGGTAAGTGGCAGAGGTGAGGGGATAAGTTAGAATGTAAAAGGGCAGTAATTAGGGGTGAGGGAAAGGAGATA
GGGGACCCTAGGAGGTAGAGTGGGACCATGTCGTGAGGCAGTTGAAGAGTTGAGGAAAGGTTTTTCTGGGCCCTACTGCTCCCCTCTGCT
GCAGGTAAGTCAGAGCAGCTTTACCACAGCTTCAGGCCACGAGAGCCCCTTCACCCGCCCTGCTGCGCCATAGGCAGAGGCTTATAAAGA
AATGGGTTCTGGGCCAGGTGTGGTGGCTCAAGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGTGGATCACCTGAGGTTAGGAGTT
CGAGATCAGCCTGGCCAACATGGTGAAACCCTGTCTACTAAAAATAAAAAAATTAGCTGGGCGTGGTGGTGGGCGCCTGTAATCCCAGCT
ACTCGGGAGGTTTAGGCAGGAGAATCGCTTGAACCCTGGAGGTGGAGGTGGAGGTTGCAGTGAGCCGAGATCGCGCCATTGCACTCCAAC
CTAGGTGACAAAGCTACACGCCATCTCAAAAAAAAAAAAGAAAAAGGGTTACAAAAGGTTCCCAGCTCCGGGGCATCAGCCTGAGTGCGC
TTGAGCTGCTCCAAACCTGGCCCTTCCCCACTCCTCTAGCATCGCCACCCGCATGGCCCTGGAACTCCCGCGGCGGCGGGGGCGGGCCCG
TGCCTGCTGTGCCCCGACTTCCCACACCAGCCGCGCCCACCGCAGGTGGGACTCAGGTTCGCCCTCTGGGCCAGGTCCTTCACGAGGAGG
GAGCTACCCTTCGCCAGAAGTTTGTGAGAATGTGGCCGCCCTTTTCCTGCCCTCTGCCCCATGTGGGTGGGGGGCCTCGTGGCCCGGCCG
GCGCCCCGTCCCCTTCTGCATGTCTGAGGCCACCGGCAACCGCCGCCCCACTCCAGATTTGCCCCCGCCTTGTTTTGAAAGCCCCTTATT
TATAACTTTTATACTTTGTGCAGGTCGCGGCGCTTCCTGCCTCATCCTCGGCTGCATGGGGCGGGGGCGCTGTTTTTAACGTGCCCGTTT

>In-frame_ENST00000456256_ENST00000221214_TCGA-3H-AB3M-01A_PLCB2_chr15_40581473_-_MAPKBP1_chr15_42092021_length(amino acids)=2479AA_start in transcript=84_stop in transcript=7523
MASFLPFCLPVSAEILQRGTLGTMSLLNPVLLPPKVKAYLSQGERFIKWDDETTVASPVILRVDPKGYYLYWTYQSKEMEFLDITSIRDT
RFGKFAKMPKSQKLRDVFNMDFPDNSFLLKTLTVVSGPDMVDLTFHNFVSYKENVGKAWAEDVLALVKHPLTANASRSTFLDKILVKLKM
QLNSEGKIPVKNFFQMFPADRKRVEAALSACHLPKGKNDAINPEDFPEPVYKSFLMSLCPRPEIDEIFTSYHAKAKPYMTKEHLTKFINQ
KQRDSRLNSLLFPPARPDQVQGLIDKYEPSGINAQRGQLSPEGMVWFLCGPENSVLAQDKLLLHHDMTQPLNHYFINSSHNTYLTAGQFS
GLSSAEMYRQVLLSGCRCVELDCWKGKPPDEEPIITHGFTMTTDIFFKEAIEAIAESAFKTSPYPIILSFENHVDSPRQQAKMAEYCRTI
FGDMLLTEPLEKFPLKPGVPLPSPEDLRGKILIKNKKNQFSGPTSSSKDTGGEAEGSSPPSAPAGEGTVWAGEEGTELEEEEVEEEEEEE
SGNLDEEEIKKMQSDEGTAGLEVTAYEEMSSLVNYIQPTKFVSFEFSAQKNRSYVISSFTELKAYDLLSKASVQFVDYNKRQMSRIYPKG
TRMDSSNYMPQMFWNAGCQMVALNFQTMDLPMQQNMAVFEFNGQSGYLLKHEFMRRPDKQFNPFSVDRIDVVVATTLSITVISGQFLSER
SVRTYVEVELFGLPGDPKRRYRTKLSPSTNSINPVWKEEPFVFEKILMPELASLRVAVMEEGNKFLGHRIIPINALNSGYHHLCLHSESN
MPLTMPALFIFLEMKDYIPGAWADLTVALANPIKFFSAHDTKSVKLKEAMGGLPEKPFPLASPVASQVNGALAPTSNGSPEPRTASLEEL
RELKGVVKLQRRHEKELRELERRGARRWEELLQRGAAQLAELGPPGVGGVGACKLGPGKGSRKKRSLPREESAGAAPGEGPEGVDGRVRE
LKDRLELELLRQGEEQYECVLKRKEQHVAEQISKMMELAREKQAAELKALKETSENDTKEMKKKLETKRLERIQGMTKVTTDKMAQERLK
REINNSHIQEVVQVIKQMTENLERHQEKLEEKQAACLEQIREMEKQVTLEKVLGITVSGGRGLACDPRSGLVAYPAGCVVVLFNPRKHKQ
HHILNSSRKTITALAFSPDGKYLVTGESGHMPAVRVWDVAEHSQVAELQEHKYGVACVAFSPSAKYIVSVGYQHDMIVNVWAWKKNIVVA
SNKVSSRVTAVSFSEDCSYFVTAGNRHIKFWYLDDSKTSKVNATVPLLGRSGLLGELRNNLFTDVACGRGKKADSTFCITSSGLLCEFSD
RRLLDKWVELRVYPEVKDSNQACLPPSSFITCSSDNTIRLWNTESSGVHGSTLHRNILSSDLIKIIYVDGNTQALLDTELPGGDKADASL
LDPRVGIRSVCVSPNGQHLASGDRMGTLRVHELQSLSEMLKVEAHDSEILCLEYSKPDTGLKLLASASRDRLIHVLDAGREYSLQQTLDE
HSSSITAVKFAASDGQVRMISCGADKSIYFRTAQKSGDGVQFTRTHHVVRKTTLYDMDVEPSWKYTAIGCQDRNIRIFNISSGKQKKLFK
GSQGEDGTLIKVQTDPSGIYIATSCSDKNLSIFDFSSGECVATMFGHSEIVTGMKFSNDCKHLISVSGDSCIFVWRLSSEMTISMRQRLA
ELRQRQRGGKQQGPSSPQRASGPNRHQAPSMLSPGPALSSDSDKEGEDEGTEEELPALPVLAKSTKKALASVPSPALPRSLSHWEMSRAQ
ESVGFLDPAPAANPGPRRRGRWVQPGVELSVRSMLDLRQLETLAPSLQDPSQDSLAIIPSGPRKHGQEALETSLTSQNEKPPRPQASQPC
SYPHIIRLLSQEEGVFAQDLEPAPIEDGIVYPEPSDNPTMDTSEFQVQAPARGTLGRVYPGSRSSEKHSPDSACSVDYSSSCLSSPEHPT
EDSESTEPLSVDGISSDLEEPAEGDEEEEEEEGGMGPYGLQEGSPQTPDQEQFLKQHFETLASGAAPGAPVQVPERSESRSISSRFLLQV
QTRPLREPSPSSSSLALMSRPAQVPQASGEQPRGNGANPPGAPPEVEPSSGNPSPQQAASVLLPRCRLNPDSSWAPKRVATASPFSGLQK
AQSVHSLVPQERHEASLQAPSPGALLSREIEAQDGLGSLPPADGRPSRPHSYQNPTTSSMAKISRSISVGENLGLVAEPQAHAPIRVSPL
SKLALPSRAHLVLDIPKPLPDRPTLAAFSPVTKGRAPGEAEKPGFPVGLGKAHSTTERWACLGEGTTPKPRTECQAHPGPSSPCAQQLPV
SSLFQGPENLQPPPPEKTPNPMECTKPGAALSQDSEPAVSLEQCEQLVAELRGSVRQAVRLYHSVAGCKMPSAEQSRIAQLLRDTFSSVR

--------------------------------------------------------------
>In-frame_ENST00000456256_ENST00000457542_TCGA-3H-AB3M-01A_PLCB2_chr15_40581473_-_MAPKBP1_chr15_42092021_length(transcript)=10294nt_BP=3462nt
CCCCAGGGGCTATAAGAGCAACTAGATTTCTGGAGCAGCTCGGGGATGGGTGCCATTTGAGCCCAGCTTGGCTCCCCCTCCTGGCTGGCC
TCCTTCCTGCCCTTCTGCCTGCCTGTGTCTGCTGAGATTCTGCAAAGAGGAACGCTTGGCACCATGTCTCTGCTCAACCCTGTCCTGCTG
CCCCCCAAGGTGAAGGCCTATCTGAGCCAAGGGGAGCGCTTCATCAAATGGGATGATGAAACTACAGTTGCCTCTCCAGTTATCCTCCGT
GTGGATCCTAAGGGCTACTACTTATACTGGACGTATCAAAGTAAGGAGATGGAGTTTCTGGATATCACCAGCATCCGGGATACTCGCTTT
GGGAAGTTTGCCAAGATGCCCAAGAGCCAGAAGCTCCGGGACGTCTTCAACATGGACTTTCCTGATAACAGTTTCCTGCTGAAGACACTC
ACGGTGGTGTCCGGCCCGGACATGGTGGACCTCACCTTCCACAACTTCGTCTCCTACAAGGAGAACGTGGGCAAGGCCTGGGCTGAGGAC
GTACTGGCCCTAGTCAAACATCCGCTGACGGCCAACGCCTCCCGCAGCACCTTCCTGGACAAGATCCTTGTGAAGCTCAAGATGCAGCTC
AACTCTGAAGGGAAGATTCCGGTGAAGAACTTTTTCCAGATGTTTCCTGCTGACCGCAAGCGGGTGGAAGCTGCTCTCAGTGCCTGCCAC
CTCCCCAAAGGCAAAAATGACGCCATCAATCCTGAGGACTTCCCAGAACCTGTCTACAAGAGTTTCCTCATGAGCCTCTGTCCTCGGCCA
GAAATAGATGAGATCTTCACTTCTTACCATGCTAAGGCCAAACCCTACATGACGAAGGAGCACCTGACCAAATTCATCAACCAGAAACAG
CGGGACTCCCGGCTTAACTCCCTGCTGTTCCCGCCAGCACGGCCTGACCAGGTGCAGGGCCTCATCGACAAGTATGAGCCCAGTGGCATC
AATGCACAGAGGGGCCAGCTGTCACCTGAAGGCATGGTCTGGTTTCTCTGTGGGCCAGAGAACAGCGTGCTGGCCCAGGACAAGCTGCTG
CTCCACCACGACATGACGCAGCCACTCAATCATTACTTCATCAACTCGTCCCACAACACCTACCTGACAGCCGGCCAGTTCTCAGGCCTC
TCCTCGGCTGAGATGTACCGCCAGGTGCTGCTCTCTGGCTGCCGTTGCGTGGAGCTAGACTGCTGGAAGGGGAAACCCCCTGACGAGGAG
CCCATTATCACCCATGGCTTCACCATGACCACAGACATCTTCTTCAAAGAAGCAATTGAGGCTATTGCAGAAAGCGCCTTTAAGACCTCC
CCCTATCCCATCATCCTGTCGTTTGAGAACCATGTGGACTCACCCCGCCAGCAGGCTAAGATGGCTGAGTATTGCCGGACGATCTTTGGG
GATATGCTGCTCACAGAGCCCCTGGAAAAGTTCCCACTAAAACCAGGTGTCCCCCTGCCCAGCCCTGAGGATCTCAGGGGCAAGATCCTC
ATCAAGAACAAGAAGAACCAGTTTTCTGGCCCCACCTCCTCCAGTAAGGATACTGGTGGGGAGGCTGAGGGCAGCAGCCCACCCAGTGCC
CCTGCAGGTGAGGGCACAGTGTGGGCTGGCGAGGAAGGGACTGAGCTGGAGGAGGAGGAGGTGGAAGAGGAAGAGGAGGAGGAGTCAGGA
AACCTGGATGAAGAAGAGATTAAGAAGATGCAGTCGGATGAGGGCACAGCGGGCCTGGAAGTGACGGCTTATGAGGAGATGTCCAGCCTA
GTCAATTACATCCAGCCCACCAAGTTCGTCTCCTTTGAGTTCTCTGCCCAAAAGAACCGAAGTTATGTCATCTCGTCCTTCACAGAGCTC
AAGGCATATGACCTGCTCTCCAAGGCCTCGGTGCAGTTTGTGGACTACAACAAGCGCCAGATGAGCCGCATTTACCCCAAGGGAACCCGC
ATGGACTCCTCCAACTACATGCCCCAGATGTTCTGGAATGCTGGATGCCAGATGGTTGCCCTCAACTTCCAGACGATGGACTTGCCCATG
CAGCAGAACATGGCAGTATTTGAGTTCAACGGGCAGAGCGGCTACCTCCTCAAGCATGAGTTCATGCGCCGGCCGGACAAGCAGTTCAAC
CCCTTCTCAGTGGACCGCATCGACGTGGTGGTGGCCACCACCCTTTCCATTACGGTGATCTCTGGGCAGTTCCTGTCAGAACGCAGCGTG
CGCACCTATGTAGAAGTGGAGCTGTTTGGCCTTCCTGGGGACCCCAAGAGGCGCTATCGAACTAAGCTGTCACCCAGTACTAACTCCATC
AATCCTGTCTGGAAGGAGGAGCCCTTTGTCTTTGAGAAGATCTTGATGCCTGAGCTGGCCTCCCTCAGAGTGGCTGTGATGGAGGAAGGC
AACAAGTTTCTTGGACACCGCATCATCCCCATCAATGCCCTAAATTCTGGGTACCACCACCTGTGCCTGCACAGTGAGAGCAACATGCCC
CTCACCATGCCTGCGCTCTTCATCTTCCTGGAGATGAAGGACTACATACCTGGTGCTTGGGCAGATCTCACTGTGGCCCTCGCCAACCCC
ATTAAGTTCTTCAGTGCCCATGACACGAAGTCTGTGAAGCTCAAGGAGGCCATGGGAGGTCTGCCTGAGAAGCCCTTCCCACTGGCGAGT
CCAGTTGCCAGCCAGGTCAATGGGGCGTTGGCCCCAACGAGCAATGGGTCACCAGAGCCGCGGACCGCCAGCCTGGAGGAGCTCCGGGAG
CTAAAGGGCGTGGTGAAGCTGCAGCGGCGGCACGAGAAGGAGCTGCGAGAGTTGGAGCGGCGCGGAGCGCGGCGCTGGGAGGAGCTGCTG
CAGCGGGGCGCGGCGCAGCTGGCGGAGCTCGGGCCACCGGGCGTGGGGGGCGTCGGGGCCTGCAAGCTCGGTCCCGGCAAGGGCTCTCGC
AAGAAGAGGAGCCTGCCCCGCGAGGAGAGCGCCGGAGCCGCGCCGGGCGAGGGCCCTGAGGGCGTGGACGGGCGCGTGCGGGAGCTGAAA
GACAGGCTGGAGCTGGAGCTGCTGCGGCAGGGCGAGGAGCAGTACGAGTGCGTTCTGAAGCGCAAGGAGCAGCACGTGGCCGAGCAAATC
TCCAAAATGATGGAGCTGGCCAGAGAGAAACAGGCGGCAGAGCTGAAGGCCCTGAAGGAGACGTCGGAGAACGACACCAAAGAGATGAAG
AAAAAGCTGGAGACAAAGAGACTGGAGCGGATCCAGGGCATGACCAAAGTCACCACAGACAAGATGGCCCAGGAGAGGTTGAAGAGAGAG
ATTAACAACTCCCACATCCAGGAAGTAGTGCAGGTGATCAAGCAGATGACGGAGAACTTGGAGAGGCACCAGGAGAAGCTGGAGGAGAAG
CAGGCGGCTTGCCTGGAACAGATACGGGAGATGGAAAAGCAGGTGACCTTGGAGAAGGTGCTGGGAATTACAGTGTCTGGAGGCAGAGGA
CTTGCCTGTGACCCCCGATCAGGTTTAGTTGCTTACCCAGCAGGGTGTGTGGTTGTGTTGTTCAATCCCCGGAAACACAAACAGCACCAC
ATCCTCAACAGTTCCAGGAAAACCATCACTGCCCTTGCCTTCTCCCCTGATGGCAAGTACTTGGTCACTGGAGAGAGTGGGCACATGCCT
GCCGTGCGGGTTTGGGACGTGGCAGAGCACAGCCAGGTGGCCGAGCTGCAGGAGCACAAGTATGGTGTGGCTTGTGTGGCCTTCTCTCCT
AGCGCCAAGTACATTGTCTCTGTGGGCTACCAGCATGACATGATCGTCAACGTGTGGGCCTGGAAGAAAAACATTGTGGTGGCCTCCAAC
AAGGTGTCCAGTCGGGTGACAGCAGTGTCCTTCTCTGAGGATTGCAGCTACTTTGTCACTGCAGGCAACCGACACATCAAATTCTGGTAT
CTCGATGACAGCAAGACCTCAAAGGTGAATGCCACTGTGCCCTTGCTGGGCCGCTCAGGGCTGCTGGGAGAGCTACGGAACAACCTATTC
ACTGATGTGGCCTGTGGCAGAGGAAAAAAGGCGGACAGTACCTTCTGCATCACGTCCTCAGGGCTGCTGTGCGAGTTCAGTGATCGAAGG
CTTTTGGACAAGTGGGTGGAGCTGAGGACCACAGTGGCCCACTGCATCTCTGTGAGCCAAGACTACATCTTCTGTGGCTGTGCTGATGGC
ACCGTGCGCCTTTTCAACCCCTCTAACCTGCACTTCCTTAGCACCTTGCCCCGACCCCATGCTCTGGGGACAGACATTGCTAGCGTCACC
GAGGCCAGTCGCCTCTTCTCTGGAGTGGCGAATGCCAGGTATCCAGACACCATTGCCTTGACCTTTGATCCTACTAATCAGTGGCTGTCT
TGTGTGTACAACGATCATAGCATTTATGTTTGGGATGTGAGGGACCCCAAGAAAGTGGGCAAGGTGTACTCGGCTCTGTATCATTCTTCC
TGCGTCTGGAGTGTGGAGGTCTACCCCGAGGTGAAGGATAGTAACCAGGCCTGCCTGCCCCCCAGTTCCTTTATTACCTGCTCCTCAGAC
AACACCATCCGCCTGTGGAACACAGAGAGCTCCGGGGTGCATGGCTCCACCCTCCACCGAAACATCCTCAGCAGTGACCTCATTAAAATC
ATCTATGTGGATGGGAACACCCAGGCCCTGCTGGACACAGAGCTGCCTGGAGGAGACAAAGCTGATGCATCCCTGTTGGATCCCCGCGTG
GGCATCCGCTCGGTGTGTGTCAGCCCCAATGGACAGCATCTAGCATCAGGGGACCGTATGGGCACACTTAGGGTGCACGAACTTCAGTCC
CTGAGTGAGATGCTGAAGGTGGAGGCCCATGACTCTGAGATTCTGTGCCTGGAGTATTCTAAGCCAGACACAGGTCTGAAACTGCTAGCA
TCGGCGAGCCGGGACCGGCTGATCCATGTGCTGGATGCCGGGCGGGAGTACAGCCTACAGCAGACGCTGGACGAACACTCATCCTCCATC
ACTGCTGTTAAGTTTGCAGCCAGTGATGGGCAAGTCCGCATGATCAGCTGTGGAGCAGACAAGAGCATCTACTTCCGCACTGCGCAGAAG
TCTGGAGATGGAGTGCAGTTCACACGGACACACCACGTGGTGCGGAAGACGACCCTCTATGACATGGATGTGGAGCCCAGCTGGAAGTAC
ACGGCTATCGGCTGCCAGGACCGAAATATTCGGATATTTAACATCAGCAGTGGAAAGCAGAAGAAGCTGTTTAAAGGGTCACAGGGTGAG
GACGGCACACTCATTAAGGTGCAGACAGACCCCTCAGGGATCTACATTGCCACCAGCTGTTCTGACAAGAATCTCTCCATTTTTGACTTC
TCCTCAGGCGAGTGCGTGGCCACCATGTTTGGCCACTCAGAGATTGTCACTGGCATGAAATTTAGTAATGATTGTAAACATCTCATCTCT
GTGTCTGGGGACAGCTGCATATTTGTGTGGCGCCTGAGCTCTGAGATGACCATCAGCATGAGGCAGCGTCTGGCCGAGTTGCGCCAGCGT
CAGCGGGGCGGCAAGCAGCAAGGACCATCCTCTCCCCAAAGGGCTTCTGGACCCAACCGGCACCAGGCCCCATCAATGCTGTCTCCTGGA
CCGGCTCTCTCATCAGACAGTGACAAGGAGGGAGAAGATGAGGGGACTGAAGAAGAACTTCCAGCACTGCCCGTCCTTGCCAAGAGTACC
AAGAAGGCACTGGCCTCGGTCCCCAGCCCAGCTTTGCCCCGAAGCCTGTCCCACTGGGAGATGAGTCGGGCACAGGAGTCCGTGGGGTTC
CTGGACCCAGCTCCTGCAGCCAACCCAGGACCCAGAAGAAGAGGGCGCTGGGTTCAGCCAGGTGTGGAACTGAGCGTTAGATCCATGCTG
GATCTGCGGCAGCTGGAAACACTGGCCCCAAGCCTGCAGGACCCTAGCCAGGACTCGCTGGCCATCATCCCATCTGGTCCCAGGAAGCAT
GGGCAGGAGGCCCTTGAGACTTCACTCACTAGCCAGAATGAAAAGCCCCCTCGGCCTCAGGCTTCCCAACCTTGTTCCTATCCCCATATT
ATCCGATTATTGTCACAAGAGGAAGGGGTCTTTGCCCAAGATCTGGAACCTGCACCCATTGAAGATGGTATTGTCTACCCGGAGCCGAGT
GACAACCCCACCATGGATACCAGTGAGTTCCAAGTGCAGGCTCCAGCCCGGGGAACTCTGGGAAGAGTGTACCCAGGCAGCAGGAGCTCA
GAAAAGCACAGCCCTGACAGTGCCTGCTCTGTGGATTACAGCAGCAGCTGCCTTTCCAGCCCGGAGCACCCCACTGAAGACTCTGAGAGC
ACGGAGCCCCTCAGTGTGGATGGCATCTCCTCAGACCTTGAAGAGCCAGCTGAGGGTGATGAAGAAGAGGAAGAAGAGGAGGGAGGCATG
GGCCCCTATGGGCTACAGGAGGGCAGCCCCCAGACTCCAGACCAGGAGCAGTTTCTAAAACAGCACTTTGAGACTCTGGCCAGTGGAGCT
GCTCCAGGGGCCCCAGTGCAGGTCCCAGAGAGGTCAGAGTCTCGGAGTATCTCTTCACGATTCCTGTTGCAAGTACAGACCCGCCCACTC
AGGGAACCATCCCCATCCTCCTCAAGCCTGGCACTGATGTCGAGACCAGCCCAGGTGCCACAGGCATCTGGTGAGCAGCCGAGAGGCAAT
GGTGCCAATCCCCCTGGAGCACCCCCGGAGGTGGAACCGTCCTCTGGCAACCCCAGCCCCCAGCAGGCAGCCTCTGTGCTGTTGCCACGA
TGCCGTCTCAACCCTGACAGCAGCTGGGCTCCCAAGAGAGTGGCCACAGCCAGCCCCTTTTCTGGACTCCAGAAGGCCCAGTCTGTGCAC
AGTCTGGTGCCACAGGAAAGACATGAGGCCAGTCTGCAGGCCCCTTCACCAGGCGCACTGCTGTCTCGGGAGATCGAAGCTCAGGATGGT
CTGGGCTCCCTGCCCCCAGCTGATGGCCGTCCGTCTCGGCCTCACTCCTATCAGAACCCCACCACCAGTTCCATGGCCAAGATATCCCGC
AGTATCTCTGTTGGGGAGAACCTGGGCCTGGTGGCTGAACCTCAAGCTCATGCCCCCATCCGAGTCTCACCACTCAGCAAGCTGGCCCTG
CCCAGCCGGGCTCACCTGGTCCTGGACATCCCCAAACCACTGCCTGACCGTCCTACCCTGGCTGCATTCTCTCCTGTCACCAAAGGCCGG
GCCCCTGGCGAGGCAGAAAAGCCTGGCTTCCCGGTGGGCCTAGGAAAAGCTCACAGTACAACTGAGAGATGGGCCTGTTTGGGGGAGGGC
ACCACTCCCAAGCCTAGGACAGAGTGCCAGGCTCATCCTGGGCCCAGCAGCCCCTGTGCCCAGCAACTGCCAGTCAGCAGCCTCTTCCAA
GGCCCTGAAAACTTGCAGCCCCCACCCCCTGAGAAGACTCCCAACCCCATGGAATGCACCAAGCCAGGGGCAGCCCTGAGCCAGGACTCA
GAGCCAGCGGTGAGCCTGGAGCAGTGTGAGCAGCTGGTGGCAGAGCTCCGCGGCAGCGTGCGCCAGGCAGTGCGGCTCTACCACTCGGTG
GCTGGCTGCAAGATGCCCTCAGCAGAGCAAAGTCGGATTGCCCAGCTCCTCAGAGACACCTTCTCTTCAGTGCGACAGGAGCTGGAAGCT
GTGGCTGGGGCAGTGCTGTCCAGCCCAGGCAGCAGCCCTGGGGCTGTGGGAGCCGAGCAGACACAGGCCCTGCTGGAGCAATACTCAGAA
CTGTTGCTTCGAGCCGTGGAACGGCGTATGGAACGCAAACTCTGAGTTCTGGAAGCCTGTCCCAAGTGAATGAATGCTCCAGCGATTCCA
AACTGCAGCCCCTCTGCCCCTCACCAAAACCTGCGGGGCTGCTTGGAGTGGAAAGCAGGGAGCAGTGTTCAGAGGCAAAGCAGCCTTCCC
AGCCGCTCCTCGTGGGGGGCCTGTATTTATTAATTTATTTCCCTGACTGTTGCCTCACTTCCTTGGAACTCCTGCCTCCACAGCCCCTCC
AGTGGCAGGGACAGGTCTTGGGTCTTTGTCATCTTGGTGCTGTGAGAGGTAGGAGGGCAGCCTGCCCCATCTAGGAATCTGGGAAGGGCT
GGCCCTCTCTTAGAAGCCATTTGAAATTACTGCAGGGATTAGCTCCCTGTGGTGGAGCATACACAGGGTACTCTGGGGTCGAGGTGAGAG
GTGATGTGGTATTCAGTGCCCGTCAGCCAACTGTGGGCCTTCACCTCTACCTGCACTTCCCCTCTCACACCAGCTGCACTCCCGTGGCTG
CCAGAGCAGGGTGGTTTTCCCCAATACCTGGAGCTCAGAAAGGCAGAGCCATCTGGCCCTCCAGGGTGTCCCCAGCCATCAGGAGACTTG
AGTTGGTATTTGGACCTGAGCCCGCACATTCCACTCCCATTCTCCCTCCAAGAGGGGCCCAGCATTGTATTTCCCTGTGACCCCTTACTC
TCCTGGCCAGAACTTGAGCCAGCTGTGGGATGTTGCTGCAGGACAGTAAGCCCTCACCTGGGCAAACATGAAGCTCTGGCCTCCTTTCCT
CAGCCCCTTGTTCTTCCCTGTCCTCCACCCTGGACCCCAGCCGGCTGCTGGAGCCCAGAGGCCACCTTCTCCCTGCATCCTGAATGATGC
TTAGTCAGAAGCCTGTGTTGGAACATCCCTCGTTTACGGGGCGCTGGCCTACCTCCTGAGGACCTCAGCCACAGATGAGATCACACGCAT
GCACGTGCACACATGTACACACACACACCTACCTGCACAGCACGCTGTTGAGTGTTGGTTGCTAGAGTATCTGGCTGGCTGCTGTGTGCC
TGGTTTCCTCACATCCTGCCTCAGCTTCACCACCCTGGCTTATGTGGAACACCTATCAGGGAGCAGAAAAGGGGTGCAGTACACTAAGTG
AACCCAGATTCTGGATTCTTGGTGTCCACAGCCTAGCTGATACGAGATAGCCCATAGGACACCTGGTTTAGGTAGAAGGAGCCTCCTCAA
AGGCAGTGCTGGGCACCCACGGGTGTGCTGGATACTGGAGTTTGAGAGGAGGGAGGTGCTGGGGCCAAAGGAGACACTAGAAAAGTGGTA
GATGGGACAGGTAAGTGGCAGAGGTGAGGGGATAAGTTAGAATGTAAAAGGGCAGTAATTAGGGGTGAGGGAAAGGAGATAGGGGACCCT
AGGAGGTAGAGTGGGACCATGTCGTGAGGCAGTTGAAGAGTTGAGGAAAGGTTTTTCTGGGCCCTACTGCTCCCCTCTGCTGCAGGTAAG
TCAGAGCAGCTTTACCACAGCTTCAGGCCACGAGAGCCCCTTCACCCGCCCTGCTGCGCCATAGGCAGAGGCTTATAAAGAAATGGGTTC
TGGGCCAGGTGTGGTGGCTCAAGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGTGGATCACCTGAGGTTAGGAGTTCGAGATCAG
CCTGGCCAACATGGTGAAACCCTGTCTACTAAAAATAAAAAAATTAGCTGGGCGTGGTGGTGGGCGCCTGTAATCCCAGCTACTCGGGAG
GTTTAGGCAGGAGAATCGCTTGAACCCTGGAGGTGGAGGTGGAGGTTGCAGTGAGCCGAGATCGCGCCATTGCACTCCAACCTAGGTGAC
AAAGCTACACGCCATCTCAAAAAAAAAAAAGAAAAAGGGTTACAAAAGGTTCCCAGCTCCGGGGCATCAGCCTGAGTGCGCTTGAGCTGC
TCCAAACCTGGCCCTTCCCCACTCCTCTAGCATCGCCACCCGCATGGCCCTGGAACTCCCGCGGCGGCGGGGGCGGGCCCGTGCCTGCTG
TGCCCCGACTTCCCACACCAGCCGCGCCCACCGCAGGTGGGACTCAGGTTCGCCCTCTGGGCCAGGTCCTTCACGAGGAGGGAGCTACCC
TTCGCCAGAAGTTTGTGAGAATGTGGCCGCCCTTTTCCTGCCCTCTGCCCCATGTGGGTGGGGGGCCTCGTGGCCCGGCCGGCGCCCCGT
CCCCTTCTGCATGTCTGAGGCCACCGGCAACCGCCGCCCCACTCCAGATTTGCCCCCGCCTTGTTTTGAAAGCCCCTTATTTATAACTTT
TATACTTTGTGCAGGTCGCGGCGCTTCCTGCCTCATCCTCGGCTGCATGGGGCGGGGGCGCTGTTTTTAACGTGCCCGTTTGTACTGATG

>In-frame_ENST00000456256_ENST00000457542_TCGA-3H-AB3M-01A_PLCB2_chr15_40581473_-_MAPKBP1_chr15_42092021_length(amino acids)=2596AA_start in transcript=84_stop in transcript=7874
MASFLPFCLPVSAEILQRGTLGTMSLLNPVLLPPKVKAYLSQGERFIKWDDETTVASPVILRVDPKGYYLYWTYQSKEMEFLDITSIRDT
RFGKFAKMPKSQKLRDVFNMDFPDNSFLLKTLTVVSGPDMVDLTFHNFVSYKENVGKAWAEDVLALVKHPLTANASRSTFLDKILVKLKM
QLNSEGKIPVKNFFQMFPADRKRVEAALSACHLPKGKNDAINPEDFPEPVYKSFLMSLCPRPEIDEIFTSYHAKAKPYMTKEHLTKFINQ
KQRDSRLNSLLFPPARPDQVQGLIDKYEPSGINAQRGQLSPEGMVWFLCGPENSVLAQDKLLLHHDMTQPLNHYFINSSHNTYLTAGQFS
GLSSAEMYRQVLLSGCRCVELDCWKGKPPDEEPIITHGFTMTTDIFFKEAIEAIAESAFKTSPYPIILSFENHVDSPRQQAKMAEYCRTI
FGDMLLTEPLEKFPLKPGVPLPSPEDLRGKILIKNKKNQFSGPTSSSKDTGGEAEGSSPPSAPAGEGTVWAGEEGTELEEEEVEEEEEEE
SGNLDEEEIKKMQSDEGTAGLEVTAYEEMSSLVNYIQPTKFVSFEFSAQKNRSYVISSFTELKAYDLLSKASVQFVDYNKRQMSRIYPKG
TRMDSSNYMPQMFWNAGCQMVALNFQTMDLPMQQNMAVFEFNGQSGYLLKHEFMRRPDKQFNPFSVDRIDVVVATTLSITVISGQFLSER
SVRTYVEVELFGLPGDPKRRYRTKLSPSTNSINPVWKEEPFVFEKILMPELASLRVAVMEEGNKFLGHRIIPINALNSGYHHLCLHSESN
MPLTMPALFIFLEMKDYIPGAWADLTVALANPIKFFSAHDTKSVKLKEAMGGLPEKPFPLASPVASQVNGALAPTSNGSPEPRTASLEEL
RELKGVVKLQRRHEKELRELERRGARRWEELLQRGAAQLAELGPPGVGGVGACKLGPGKGSRKKRSLPREESAGAAPGEGPEGVDGRVRE
LKDRLELELLRQGEEQYECVLKRKEQHVAEQISKMMELAREKQAAELKALKETSENDTKEMKKKLETKRLERIQGMTKVTTDKMAQERLK
REINNSHIQEVVQVIKQMTENLERHQEKLEEKQAACLEQIREMEKQVTLEKVLGITVSGGRGLACDPRSGLVAYPAGCVVVLFNPRKHKQ
HHILNSSRKTITALAFSPDGKYLVTGESGHMPAVRVWDVAEHSQVAELQEHKYGVACVAFSPSAKYIVSVGYQHDMIVNVWAWKKNIVVA
SNKVSSRVTAVSFSEDCSYFVTAGNRHIKFWYLDDSKTSKVNATVPLLGRSGLLGELRNNLFTDVACGRGKKADSTFCITSSGLLCEFSD
RRLLDKWVELRTTVAHCISVSQDYIFCGCADGTVRLFNPSNLHFLSTLPRPHALGTDIASVTEASRLFSGVANARYPDTIALTFDPTNQW
LSCVYNDHSIYVWDVRDPKKVGKVYSALYHSSCVWSVEVYPEVKDSNQACLPPSSFITCSSDNTIRLWNTESSGVHGSTLHRNILSSDLI
KIIYVDGNTQALLDTELPGGDKADASLLDPRVGIRSVCVSPNGQHLASGDRMGTLRVHELQSLSEMLKVEAHDSEILCLEYSKPDTGLKL
LASASRDRLIHVLDAGREYSLQQTLDEHSSSITAVKFAASDGQVRMISCGADKSIYFRTAQKSGDGVQFTRTHHVVRKTTLYDMDVEPSW
KYTAIGCQDRNIRIFNISSGKQKKLFKGSQGEDGTLIKVQTDPSGIYIATSCSDKNLSIFDFSSGECVATMFGHSEIVTGMKFSNDCKHL
ISVSGDSCIFVWRLSSEMTISMRQRLAELRQRQRGGKQQGPSSPQRASGPNRHQAPSMLSPGPALSSDSDKEGEDEGTEEELPALPVLAK
STKKALASVPSPALPRSLSHWEMSRAQESVGFLDPAPAANPGPRRRGRWVQPGVELSVRSMLDLRQLETLAPSLQDPSQDSLAIIPSGPR
KHGQEALETSLTSQNEKPPRPQASQPCSYPHIIRLLSQEEGVFAQDLEPAPIEDGIVYPEPSDNPTMDTSEFQVQAPARGTLGRVYPGSR
SSEKHSPDSACSVDYSSSCLSSPEHPTEDSESTEPLSVDGISSDLEEPAEGDEEEEEEEGGMGPYGLQEGSPQTPDQEQFLKQHFETLAS
GAAPGAPVQVPERSESRSISSRFLLQVQTRPLREPSPSSSSLALMSRPAQVPQASGEQPRGNGANPPGAPPEVEPSSGNPSPQQAASVLL
PRCRLNPDSSWAPKRVATASPFSGLQKAQSVHSLVPQERHEASLQAPSPGALLSREIEAQDGLGSLPPADGRPSRPHSYQNPTTSSMAKI
SRSISVGENLGLVAEPQAHAPIRVSPLSKLALPSRAHLVLDIPKPLPDRPTLAAFSPVTKGRAPGEAEKPGFPVGLGKAHSTTERWACLG
EGTTPKPRTECQAHPGPSSPCAQQLPVSSLFQGPENLQPPPPEKTPNPMECTKPGAALSQDSEPAVSLEQCEQLVAELRGSVRQAVRLYH

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Fusion Gene PPI Analysis for PLCB2-MAPKBP1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for PLCB2-MAPKBP1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for PLCB2-MAPKBP1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneMAPKBP1C1855681Nephronophthisis, familial juvenile1ORPHANET
TgeneMAPKBP1C4310640NEPHRONOPHTHISIS 201CTD_human;GENOMICS_ENGLAND;UNIPROT