FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:PLXDC2-SYNE1 (FusionGDB2 ID:66099)

Fusion Gene Summary for PLXDC2-SYNE1

check button Fusion gene summary
Fusion gene informationFusion gene name: PLXDC2-SYNE1
Fusion gene ID: 66099
HgeneTgene
Gene symbol

PLXDC2

SYNE1

Gene ID

84898

23345

Gene nameplexin domain containing 2spectrin repeat containing nuclear envelope protein 1
SynonymsTEM7R8B|AMCM|ARCA1|C6orf98|CPG2|EDMD4|KASH1|MYNE1|Nesp1|SCAR8|dJ45H2.2
Cytomap

10p12.31

6q25.2

Type of geneprotein-codingprotein-coding
Descriptionplexin domain-containing protein 21200007L24Riktumor endothelial marker 7-related proteinnesprin-1CPG2 full lengthKASH domain-containing protein 1enaptinmyocyte nuclear envelope protein 1nesprin 1spectrin repeat containing, nuclear envelope 1synaptic nuclear envelope protein 1synaptic nuclei expressed gene 1
Modification date2020031320200320
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000377242, ENST00000377252, 
ENST00000377238, 		ENST00000367255, 
ENST00000356820, ENST00000423061, 
ENST00000448038, ENST00000341594, 
ENST00000265368, ENST00000367253, 
ENST00000367248, ENST00000413186, 
ENST00000466159, ENST00000539504, 
ENST00000347037, ENST00000354674, 
ENST00000495090, 
Fusion gene scores* DoF score19 X 12 X 11=250816 X 18 X 9=2592
# samples 1918
** MAII scorelog2(19/2508*10)=-3.72246602447109
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(18/2592*10)=-3.84799690655495
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: PLXDC2 [Title/Abstract] AND SYNE1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointPLXDC2(20290915)-SYNE1(152793548), # samples:4
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneSYNE1

GO:0007030

Golgi organization

12808039

TgeneSYNE1

GO:0042692

muscle cell differentiation

11792814

TgeneSYNE1

GO:0090286

cytoskeletal anchoring at nuclear membrane

18396275

TgeneSYNE1

GO:0090292

nuclear matrix anchoring at nuclear membrane

11801724


check buttonFusion gene breakpoints across PLXDC2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across SYNE1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-A8-A07R-01APLXDC2chr10

20290915

+SYNE1chr6

152793548

-
ChimerDB4BRCATCGA-A8-A07RPLXDC2chr10

20290915

+SYNE1chr6

152793548

-
ChimerDB4BRCATCGA-A8-A07R-01APLXDC2chr10

20290915

+SYNE1chr6

152793548

-
ChimerDB4BRCATCGA-A8-A07R-01APLXDC2chr10

20290915

-SYNE1chr6

152793548

-


Top

Fusion Gene ORF analysis for PLXDC2-SYNE1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000377242ENST00000367255PLXDC2chr10

20290915

+SYNE1chr6

152793548

-
5CDS-intronENST00000377242ENST00000356820PLXDC2chr10

20290915

+SYNE1chr6

152793548

-
5CDS-intronENST00000377242ENST00000423061PLXDC2chr10

20290915

+SYNE1chr6

152793548

-
5CDS-intronENST00000377242ENST00000448038PLXDC2chr10

20290915

+SYNE1chr6

152793548

-
5CDS-intronENST00000377242ENST00000341594PLXDC2chr10

20290915

+SYNE1chr6

152793548

-
5CDS-intronENST00000377242ENST00000265368PLXDC2chr10

20290915

+SYNE1chr6

152793548

-
5CDS-intronENST00000377242ENST00000367253PLXDC2chr10

20290915

+SYNE1chr6

152793548

-
5CDS-intronENST00000377242ENST00000367248PLXDC2chr10

20290915

+SYNE1chr6

152793548

-
5CDS-intronENST00000377242ENST00000413186PLXDC2chr10

20290915

+SYNE1chr6

152793548

-
5CDS-intronENST00000377242ENST00000466159PLXDC2chr10

20290915

+SYNE1chr6

152793548

-
5CDS-intronENST00000377242ENST00000539504PLXDC2chr10

20290915

+SYNE1chr6

152793548

-
5CDS-intronENST00000377242ENST00000347037PLXDC2chr10

20290915

+SYNE1chr6

152793548

-
5CDS-intronENST00000377242ENST00000354674PLXDC2chr10

20290915

+SYNE1chr6

152793548

-
5CDS-intronENST00000377242ENST00000495090PLXDC2chr10

20290915

+SYNE1chr6

152793548

-
In-frameENST00000377252ENST00000367255PLXDC2chr10

20290915

+SYNE1chr6

152793548

-
5CDS-intronENST00000377252ENST00000356820PLXDC2chr10

20290915

+SYNE1chr6

152793548

-
5CDS-intronENST00000377252ENST00000423061PLXDC2chr10

20290915

+SYNE1chr6

152793548

-
5CDS-intronENST00000377252ENST00000448038PLXDC2chr10

20290915

+SYNE1chr6

152793548

-
5CDS-intronENST00000377252ENST00000341594PLXDC2chr10

20290915

+SYNE1chr6

152793548

-
5CDS-intronENST00000377252ENST00000265368PLXDC2chr10

20290915

+SYNE1chr6

152793548

-
5CDS-intronENST00000377252ENST00000367253PLXDC2chr10

20290915

+SYNE1chr6

152793548

-
5CDS-intronENST00000377252ENST00000367248PLXDC2chr10

20290915

+SYNE1chr6

152793548

-
5CDS-intronENST00000377252ENST00000413186PLXDC2chr10

20290915

+SYNE1chr6

152793548

-
5CDS-intronENST00000377252ENST00000466159PLXDC2chr10

20290915

+SYNE1chr6

152793548

-
5CDS-intronENST00000377252ENST00000539504PLXDC2chr10

20290915

+SYNE1chr6

152793548

-
5CDS-intronENST00000377252ENST00000347037PLXDC2chr10

20290915

+SYNE1chr6

152793548

-
5CDS-intronENST00000377252ENST00000354674PLXDC2chr10

20290915

+SYNE1chr6

152793548

-
5CDS-intronENST00000377252ENST00000495090PLXDC2chr10

20290915

+SYNE1chr6

152793548

-
intron-3CDSENST00000377238ENST00000367255PLXDC2chr10

20290915

+SYNE1chr6

152793548

-
intron-intronENST00000377238ENST00000356820PLXDC2chr10

20290915

+SYNE1chr6

152793548

-
intron-intronENST00000377238ENST00000423061PLXDC2chr10

20290915

+SYNE1chr6

152793548

-
intron-intronENST00000377238ENST00000448038PLXDC2chr10

20290915

+SYNE1chr6

152793548

-
intron-intronENST00000377238ENST00000341594PLXDC2chr10

20290915

+SYNE1chr6

152793548

-
intron-intronENST00000377238ENST00000265368PLXDC2chr10

20290915

+SYNE1chr6

152793548

-
intron-intronENST00000377238ENST00000367253PLXDC2chr10

20290915

+SYNE1chr6

152793548

-
intron-intronENST00000377238ENST00000367248PLXDC2chr10

20290915

+SYNE1chr6

152793548

-
intron-intronENST00000377238ENST00000413186PLXDC2chr10

20290915

+SYNE1chr6

152793548

-
intron-intronENST00000377238ENST00000466159PLXDC2chr10

20290915

+SYNE1chr6

152793548

-
intron-intronENST00000377238ENST00000539504PLXDC2chr10

20290915

+SYNE1chr6

152793548

-
intron-intronENST00000377238ENST00000347037PLXDC2chr10

20290915

+SYNE1chr6

152793548

-
intron-intronENST00000377238ENST00000354674PLXDC2chr10

20290915

+SYNE1chr6

152793548

-
intron-intronENST00000377238ENST00000495090PLXDC2chr10

20290915

+SYNE1chr6

152793548

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000377242PLXDC2chr1020290915+ENST00000367255SYNE1chr6152793548-269611165841262088455
ENST00000377252PLXDC2chr1020290915+ENST00000367255SYNE1chr6152793548-269611165841262088455

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000377242ENST00000367255PLXDC2chr1020290915+SYNE1chr6152793548-0.0088954120.99110454
ENST00000377252ENST00000367255PLXDC2chr1020290915+SYNE1chr6152793548-0.0088954120.99110454

Top

Fusion Genomic Features for PLXDC2-SYNE1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

Top

Fusion Protein Features for PLXDC2-SYNE1


check button Go to

FGviewer for the breakpoints of chr10:20290915-chr6:152793548

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311368663_8729450.01726.0Compositional biasNote=Ser-rich
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131468663_8729450.08798.0Compositional biasNote=Ser-rich
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611318663_8729450.01444.0Compositional biasNote=Ser-rich
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131468663_8729457.08750.0Compositional biasNote=Ser-rich
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311368738_8797450.01726.0DomainKASH
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131468738_8797450.08798.0DomainKASH
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611318738_8797450.01444.0DomainKASH
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131468738_8797457.08750.0DomainKASH
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311361025_1122450.01726.0RepeatNote=Spectrin 8
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311361123_1246450.01726.0RepeatNote=Spectrin 9
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311361247_1335450.01726.0RepeatNote=Spectrin 10
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311361336_1444450.01726.0RepeatNote=Spectrin 11
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311361445_1550450.01726.0RepeatNote=Spectrin 12
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311361551_1653450.01726.0RepeatNote=Spectrin 13
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311361654_1763450.01726.0RepeatNote=Spectrin 14
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311361764_1879450.01726.0RepeatNote=Spectrin 15
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311361880_1976450.01726.0RepeatNote=Spectrin 16
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311361977_2081450.01726.0RepeatNote=Spectrin 17
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311362082_2195450.01726.0RepeatNote=Spectrin 18
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311362196_2303450.01726.0RepeatNote=Spectrin 19
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311362304_2401450.01726.0RepeatNote=Spectrin 20
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311362402_2513450.01726.0RepeatNote=Spectrin 21
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311362514_2619450.01726.0RepeatNote=Spectrin 22
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311362620_2731450.01726.0RepeatNote=Spectrin 23
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311362732_2838450.01726.0RepeatNote=Spectrin 24
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311362839_2962450.01726.0RepeatNote=Spectrin 25
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311362963_3062450.01726.0RepeatNote=Spectrin 26
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311363063_3171450.01726.0RepeatNote=Spectrin 27
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311363172_3275450.01726.0RepeatNote=Spectrin 28
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311363276_3387450.01726.0RepeatNote=Spectrin 29
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311363388_3490450.01726.0RepeatNote=Spectrin 30
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311363491_3593450.01726.0RepeatNote=Spectrin 31
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311363594_3720450.01726.0RepeatNote=Spectrin 32
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311363721_3814450.01726.0RepeatNote=Spectrin 33
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311363815_3920450.01726.0RepeatNote=Spectrin 34
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311363921_4028450.01726.0RepeatNote=Spectrin 35
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311364029_4139450.01726.0RepeatNote=Spectrin 36
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311364140_4235450.01726.0RepeatNote=Spectrin 37
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311364236_4339450.01726.0RepeatNote=Spectrin 38
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311364340_4451450.01726.0RepeatNote=Spectrin 39
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311364452_4560450.01726.0RepeatNote=Spectrin 40
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311364561_4669450.01726.0RepeatNote=Spectrin 41
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311364670_4776450.01726.0RepeatNote=Spectrin 42
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311364777_4882450.01726.0RepeatNote=Spectrin 43
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311364883_4991450.01726.0RepeatNote=Spectrin 44
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311364992_5099450.01726.0RepeatNote=Spectrin 45
TgeneSYNE1chr10:20290915chr6:152793548ENST000003672531136503_609450.01726.0RepeatNote=Spectrin 3
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311365100_5209450.01726.0RepeatNote=Spectrin 46
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311365210_5318450.01726.0RepeatNote=Spectrin 47
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311365319_5424450.01726.0RepeatNote=Spectrin 48
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311365425_5522450.01726.0RepeatNote=Spectrin 49
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311365523_5630450.01726.0RepeatNote=Spectrin 50
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311365631_5736450.01726.0RepeatNote=Spectrin 51
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311365737_5842450.01726.0RepeatNote=Spectrin 52
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311365962_6071450.01726.0RepeatNote=Spectrin 53
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311366072_6178450.01726.0RepeatNote=Spectrin 54
TgeneSYNE1chr10:20290915chr6:152793548ENST000003672531136610_703450.01726.0RepeatNote=Spectrin 4
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311366374_6485450.01726.0RepeatNote=Spectrin 55
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311366486_6581450.01726.0RepeatNote=Spectrin 56
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311366582_6691450.01726.0RepeatNote=Spectrin 57
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311366692_6795450.01726.0RepeatNote=Spectrin 58
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311366796_6902450.01726.0RepeatNote=Spectrin 59
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311366903_7020450.01726.0RepeatNote=Spectrin 60
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311367021_7128450.01726.0RepeatNote=Spectrin 61
TgeneSYNE1chr10:20290915chr6:152793548ENST000003672531136704_815450.01726.0RepeatNote=Spectrin 5
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311367129_7237450.01726.0RepeatNote=Spectrin 62
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311367238_7350450.01726.0RepeatNote=Spectrin 63
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311367351_7454450.01726.0RepeatNote=Spectrin 64
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311367455_7558450.01726.0RepeatNote=Spectrin 65
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311367559_7671450.01726.0RepeatNote=Spectrin 66
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311367672_7783450.01726.0RepeatNote=Spectrin 67
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311367784_7883450.01726.0RepeatNote=Spectrin 68
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311367884_7997450.01726.0RepeatNote=Spectrin 69
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311367998_8106450.01726.0RepeatNote=Spectrin 70
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311368107_8216450.01726.0RepeatNote=Spectrin 71
TgeneSYNE1chr10:20290915chr6:152793548ENST000003672531136816_923450.01726.0RepeatNote=Spectrin 6
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311368329_8438450.01726.0RepeatNote=Spectrin 72
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311368439_8548450.01726.0RepeatNote=Spectrin 73
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311368549_8666450.01726.0RepeatNote=Spectrin 74
TgeneSYNE1chr10:20290915chr6:152793548ENST000003672531136924_1024450.01726.0RepeatNote=Spectrin 7
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131461025_1122450.08798.0RepeatNote=Spectrin 8
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131461123_1246450.08798.0RepeatNote=Spectrin 9
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131461247_1335450.08798.0RepeatNote=Spectrin 10
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131461336_1444450.08798.0RepeatNote=Spectrin 11
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131461445_1550450.08798.0RepeatNote=Spectrin 12
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131461551_1653450.08798.0RepeatNote=Spectrin 13
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131461654_1763450.08798.0RepeatNote=Spectrin 14
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131461764_1879450.08798.0RepeatNote=Spectrin 15
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131461880_1976450.08798.0RepeatNote=Spectrin 16
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131461977_2081450.08798.0RepeatNote=Spectrin 17
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131462082_2195450.08798.0RepeatNote=Spectrin 18
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131462196_2303450.08798.0RepeatNote=Spectrin 19
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131462304_2401450.08798.0RepeatNote=Spectrin 20
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131462402_2513450.08798.0RepeatNote=Spectrin 21
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131462514_2619450.08798.0RepeatNote=Spectrin 22
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131462620_2731450.08798.0RepeatNote=Spectrin 23
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131462732_2838450.08798.0RepeatNote=Spectrin 24
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131462839_2962450.08798.0RepeatNote=Spectrin 25
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131462963_3062450.08798.0RepeatNote=Spectrin 26
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131463063_3171450.08798.0RepeatNote=Spectrin 27
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131463172_3275450.08798.0RepeatNote=Spectrin 28
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131463276_3387450.08798.0RepeatNote=Spectrin 29
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131463388_3490450.08798.0RepeatNote=Spectrin 30
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131463491_3593450.08798.0RepeatNote=Spectrin 31
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131463594_3720450.08798.0RepeatNote=Spectrin 32
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131463721_3814450.08798.0RepeatNote=Spectrin 33
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131463815_3920450.08798.0RepeatNote=Spectrin 34
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131463921_4028450.08798.0RepeatNote=Spectrin 35
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131464029_4139450.08798.0RepeatNote=Spectrin 36
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131464140_4235450.08798.0RepeatNote=Spectrin 37
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131464236_4339450.08798.0RepeatNote=Spectrin 38
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131464340_4451450.08798.0RepeatNote=Spectrin 39
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131464452_4560450.08798.0RepeatNote=Spectrin 40
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131464561_4669450.08798.0RepeatNote=Spectrin 41
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131464670_4776450.08798.0RepeatNote=Spectrin 42
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131464777_4882450.08798.0RepeatNote=Spectrin 43
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131464883_4991450.08798.0RepeatNote=Spectrin 44
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131464992_5099450.08798.0RepeatNote=Spectrin 45
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725513146503_609450.08798.0RepeatNote=Spectrin 3
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131465100_5209450.08798.0RepeatNote=Spectrin 46
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131465210_5318450.08798.0RepeatNote=Spectrin 47
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131465319_5424450.08798.0RepeatNote=Spectrin 48
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131465425_5522450.08798.0RepeatNote=Spectrin 49
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131465523_5630450.08798.0RepeatNote=Spectrin 50
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131465631_5736450.08798.0RepeatNote=Spectrin 51
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131465737_5842450.08798.0RepeatNote=Spectrin 52
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131465962_6071450.08798.0RepeatNote=Spectrin 53
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131466072_6178450.08798.0RepeatNote=Spectrin 54
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725513146610_703450.08798.0RepeatNote=Spectrin 4
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131466374_6485450.08798.0RepeatNote=Spectrin 55
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131466486_6581450.08798.0RepeatNote=Spectrin 56
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131466582_6691450.08798.0RepeatNote=Spectrin 57
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131466692_6795450.08798.0RepeatNote=Spectrin 58
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131466796_6902450.08798.0RepeatNote=Spectrin 59
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131466903_7020450.08798.0RepeatNote=Spectrin 60
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131467021_7128450.08798.0RepeatNote=Spectrin 61
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725513146704_815450.08798.0RepeatNote=Spectrin 5
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131467129_7237450.08798.0RepeatNote=Spectrin 62
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131467238_7350450.08798.0RepeatNote=Spectrin 63
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131467351_7454450.08798.0RepeatNote=Spectrin 64
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131467455_7558450.08798.0RepeatNote=Spectrin 65
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131467559_7671450.08798.0RepeatNote=Spectrin 66
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131467672_7783450.08798.0RepeatNote=Spectrin 67
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131467784_7883450.08798.0RepeatNote=Spectrin 68
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131467884_7997450.08798.0RepeatNote=Spectrin 69
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131467998_8106450.08798.0RepeatNote=Spectrin 70
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131468107_8216450.08798.0RepeatNote=Spectrin 71
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725513146816_923450.08798.0RepeatNote=Spectrin 6
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131468329_8438450.08798.0RepeatNote=Spectrin 72
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131468439_8548450.08798.0RepeatNote=Spectrin 73
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131468549_8666450.08798.0RepeatNote=Spectrin 74
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725513146924_1024450.08798.0RepeatNote=Spectrin 7
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611311025_1122450.01444.0RepeatNote=Spectrin 8
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611311123_1246450.01444.0RepeatNote=Spectrin 9
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611311247_1335450.01444.0RepeatNote=Spectrin 10
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611311336_1444450.01444.0RepeatNote=Spectrin 11
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611311445_1550450.01444.0RepeatNote=Spectrin 12
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611311551_1653450.01444.0RepeatNote=Spectrin 13
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611311654_1763450.01444.0RepeatNote=Spectrin 14
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611311764_1879450.01444.0RepeatNote=Spectrin 15
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611311880_1976450.01444.0RepeatNote=Spectrin 16
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611311977_2081450.01444.0RepeatNote=Spectrin 17
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611312082_2195450.01444.0RepeatNote=Spectrin 18
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611312196_2303450.01444.0RepeatNote=Spectrin 19
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611312304_2401450.01444.0RepeatNote=Spectrin 20
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611312402_2513450.01444.0RepeatNote=Spectrin 21
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611312514_2619450.01444.0RepeatNote=Spectrin 22
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611312620_2731450.01444.0RepeatNote=Spectrin 23
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611312732_2838450.01444.0RepeatNote=Spectrin 24
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611312839_2962450.01444.0RepeatNote=Spectrin 25
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611312963_3062450.01444.0RepeatNote=Spectrin 26
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611313063_3171450.01444.0RepeatNote=Spectrin 27
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611313172_3275450.01444.0RepeatNote=Spectrin 28
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611313276_3387450.01444.0RepeatNote=Spectrin 29
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611313388_3490450.01444.0RepeatNote=Spectrin 30
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611313491_3593450.01444.0RepeatNote=Spectrin 31
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611313594_3720450.01444.0RepeatNote=Spectrin 32
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611313721_3814450.01444.0RepeatNote=Spectrin 33
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611313815_3920450.01444.0RepeatNote=Spectrin 34
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611313921_4028450.01444.0RepeatNote=Spectrin 35
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611314029_4139450.01444.0RepeatNote=Spectrin 36
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611314140_4235450.01444.0RepeatNote=Spectrin 37
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611314236_4339450.01444.0RepeatNote=Spectrin 38
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611314340_4451450.01444.0RepeatNote=Spectrin 39
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611314452_4560450.01444.0RepeatNote=Spectrin 40
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611314561_4669450.01444.0RepeatNote=Spectrin 41
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611314670_4776450.01444.0RepeatNote=Spectrin 42
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611314777_4882450.01444.0RepeatNote=Spectrin 43
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611314883_4991450.01444.0RepeatNote=Spectrin 44
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611314992_5099450.01444.0RepeatNote=Spectrin 45
TgeneSYNE1chr10:20290915chr6:152793548ENST000004131861131503_609450.01444.0RepeatNote=Spectrin 3
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611315100_5209450.01444.0RepeatNote=Spectrin 46
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611315210_5318450.01444.0RepeatNote=Spectrin 47
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611315319_5424450.01444.0RepeatNote=Spectrin 48
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611315425_5522450.01444.0RepeatNote=Spectrin 49
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611315523_5630450.01444.0RepeatNote=Spectrin 50
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611315631_5736450.01444.0RepeatNote=Spectrin 51
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611315737_5842450.01444.0RepeatNote=Spectrin 52
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611315962_6071450.01444.0RepeatNote=Spectrin 53
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611316072_6178450.01444.0RepeatNote=Spectrin 54
TgeneSYNE1chr10:20290915chr6:152793548ENST000004131861131610_703450.01444.0RepeatNote=Spectrin 4
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611316374_6485450.01444.0RepeatNote=Spectrin 55
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611316486_6581450.01444.0RepeatNote=Spectrin 56
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611316582_6691450.01444.0RepeatNote=Spectrin 57
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611316692_6795450.01444.0RepeatNote=Spectrin 58
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611316796_6902450.01444.0RepeatNote=Spectrin 59
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611316903_7020450.01444.0RepeatNote=Spectrin 60
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611317021_7128450.01444.0RepeatNote=Spectrin 61
TgeneSYNE1chr10:20290915chr6:152793548ENST000004131861131704_815450.01444.0RepeatNote=Spectrin 5
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611317129_7237450.01444.0RepeatNote=Spectrin 62
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611317238_7350450.01444.0RepeatNote=Spectrin 63
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611317351_7454450.01444.0RepeatNote=Spectrin 64
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611317455_7558450.01444.0RepeatNote=Spectrin 65
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611317559_7671450.01444.0RepeatNote=Spectrin 66
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611317672_7783450.01444.0RepeatNote=Spectrin 67
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611317784_7883450.01444.0RepeatNote=Spectrin 68
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611317884_7997450.01444.0RepeatNote=Spectrin 69
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611317998_8106450.01444.0RepeatNote=Spectrin 70
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611318107_8216450.01444.0RepeatNote=Spectrin 71
TgeneSYNE1chr10:20290915chr6:152793548ENST000004131861131816_923450.01444.0RepeatNote=Spectrin 6
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611318329_8438450.01444.0RepeatNote=Spectrin 72
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611318439_8548450.01444.0RepeatNote=Spectrin 73
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611318549_8666450.01444.0RepeatNote=Spectrin 74
TgeneSYNE1chr10:20290915chr6:152793548ENST000004131861131924_1024450.01444.0RepeatNote=Spectrin 7
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131461025_1122457.08750.0RepeatNote=Spectrin 8
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131461123_1246457.08750.0RepeatNote=Spectrin 9
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131461247_1335457.08750.0RepeatNote=Spectrin 10
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131461336_1444457.08750.0RepeatNote=Spectrin 11
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131461445_1550457.08750.0RepeatNote=Spectrin 12
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131461551_1653457.08750.0RepeatNote=Spectrin 13
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131461654_1763457.08750.0RepeatNote=Spectrin 14
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131461764_1879457.08750.0RepeatNote=Spectrin 15
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131461880_1976457.08750.0RepeatNote=Spectrin 16
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131461977_2081457.08750.0RepeatNote=Spectrin 17
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131462082_2195457.08750.0RepeatNote=Spectrin 18
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131462196_2303457.08750.0RepeatNote=Spectrin 19
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131462304_2401457.08750.0RepeatNote=Spectrin 20
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131462402_2513457.08750.0RepeatNote=Spectrin 21
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131462514_2619457.08750.0RepeatNote=Spectrin 22
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131462620_2731457.08750.0RepeatNote=Spectrin 23
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131462732_2838457.08750.0RepeatNote=Spectrin 24
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131462839_2962457.08750.0RepeatNote=Spectrin 25
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131462963_3062457.08750.0RepeatNote=Spectrin 26
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131463063_3171457.08750.0RepeatNote=Spectrin 27
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131463172_3275457.08750.0RepeatNote=Spectrin 28
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131463276_3387457.08750.0RepeatNote=Spectrin 29
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131463388_3490457.08750.0RepeatNote=Spectrin 30
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131463491_3593457.08750.0RepeatNote=Spectrin 31
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131463594_3720457.08750.0RepeatNote=Spectrin 32
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131463721_3814457.08750.0RepeatNote=Spectrin 33
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131463815_3920457.08750.0RepeatNote=Spectrin 34
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131463921_4028457.08750.0RepeatNote=Spectrin 35
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131464029_4139457.08750.0RepeatNote=Spectrin 36
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131464140_4235457.08750.0RepeatNote=Spectrin 37
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131464236_4339457.08750.0RepeatNote=Spectrin 38
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131464340_4451457.08750.0RepeatNote=Spectrin 39
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131464452_4560457.08750.0RepeatNote=Spectrin 40
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131464561_4669457.08750.0RepeatNote=Spectrin 41
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131464670_4776457.08750.0RepeatNote=Spectrin 42
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131464777_4882457.08750.0RepeatNote=Spectrin 43
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131464883_4991457.08750.0RepeatNote=Spectrin 44
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131464992_5099457.08750.0RepeatNote=Spectrin 45
TgeneSYNE1chr10:20290915chr6:152793548ENST0000042306113146503_609457.08750.0RepeatNote=Spectrin 3
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131465100_5209457.08750.0RepeatNote=Spectrin 46
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131465210_5318457.08750.0RepeatNote=Spectrin 47
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131465319_5424457.08750.0RepeatNote=Spectrin 48
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131465425_5522457.08750.0RepeatNote=Spectrin 49
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131465523_5630457.08750.0RepeatNote=Spectrin 50
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131465631_5736457.08750.0RepeatNote=Spectrin 51
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131465737_5842457.08750.0RepeatNote=Spectrin 52
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131465962_6071457.08750.0RepeatNote=Spectrin 53
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131466072_6178457.08750.0RepeatNote=Spectrin 54
TgeneSYNE1chr10:20290915chr6:152793548ENST0000042306113146610_703457.08750.0RepeatNote=Spectrin 4
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131466374_6485457.08750.0RepeatNote=Spectrin 55
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131466486_6581457.08750.0RepeatNote=Spectrin 56
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131466582_6691457.08750.0RepeatNote=Spectrin 57
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131466692_6795457.08750.0RepeatNote=Spectrin 58
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131466796_6902457.08750.0RepeatNote=Spectrin 59
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131466903_7020457.08750.0RepeatNote=Spectrin 60
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131467021_7128457.08750.0RepeatNote=Spectrin 61
TgeneSYNE1chr10:20290915chr6:152793548ENST0000042306113146704_815457.08750.0RepeatNote=Spectrin 5
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131467129_7237457.08750.0RepeatNote=Spectrin 62
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131467238_7350457.08750.0RepeatNote=Spectrin 63
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131467351_7454457.08750.0RepeatNote=Spectrin 64
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131467455_7558457.08750.0RepeatNote=Spectrin 65
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131467559_7671457.08750.0RepeatNote=Spectrin 66
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131467672_7783457.08750.0RepeatNote=Spectrin 67
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131467784_7883457.08750.0RepeatNote=Spectrin 68
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131467884_7997457.08750.0RepeatNote=Spectrin 69
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131467998_8106457.08750.0RepeatNote=Spectrin 70
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131468107_8216457.08750.0RepeatNote=Spectrin 71
TgeneSYNE1chr10:20290915chr6:152793548ENST0000042306113146816_923457.08750.0RepeatNote=Spectrin 6
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131468329_8438457.08750.0RepeatNote=Spectrin 72
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131468439_8548457.08750.0RepeatNote=Spectrin 73
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131468549_8666457.08750.0RepeatNote=Spectrin 74
TgeneSYNE1chr10:20290915chr6:152793548ENST0000042306113146924_1024457.08750.0RepeatNote=Spectrin 7
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311368768_8797450.01726.0Topological domainPerinuclear space
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131468768_8797450.08798.0Topological domainPerinuclear space
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611318768_8797450.01444.0Topological domainPerinuclear space
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131468768_8797457.08750.0Topological domainPerinuclear space
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311368747_8767450.01726.0TransmembraneHelical%3B Anchor for type IV membrane protein
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131468747_8767450.08798.0TransmembraneHelical%3B Anchor for type IV membrane protein
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611318747_8767450.01444.0TransmembraneHelical%3B Anchor for type IV membrane protein
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131468747_8767457.08750.0TransmembraneHelical%3B Anchor for type IV membrane protein

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePLXDC2chr10:20290915chr6:152793548ENST00000377242+213383_427108.0481.0Compositional biasNote=Thr-rich
HgenePLXDC2chr10:20290915chr6:152793548ENST00000377252+214383_427108.0530.0Compositional biasNote=Thr-rich
HgenePLXDC2chr10:20290915chr6:152793548ENST00000377242+213327_372108.0481.0DomainNote=PSI
HgenePLXDC2chr10:20290915chr6:152793548ENST00000377252+214327_372108.0530.0DomainNote=PSI
HgenePLXDC2chr10:20290915chr6:152793548ENST00000377242+21331_454108.0481.0Topological domainExtracellular
HgenePLXDC2chr10:20290915chr6:152793548ENST00000377242+213476_529108.0481.0Topological domainCytoplasmic
HgenePLXDC2chr10:20290915chr6:152793548ENST00000377252+21431_454108.0530.0Topological domainExtracellular
HgenePLXDC2chr10:20290915chr6:152793548ENST00000377252+214476_529108.0530.0Topological domainCytoplasmic
HgenePLXDC2chr10:20290915chr6:152793548ENST00000377242+213455_475108.0481.0TransmembraneHelical
HgenePLXDC2chr10:20290915chr6:152793548ENST00000377252+214455_475108.0530.0TransmembraneHelical
TgeneSYNE1chr10:20290915chr6:152793548ENST000003672531136314_8666450.01726.0Coiled coilOntology_term=ECO:0000255
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725513146314_8666450.08798.0Coiled coilOntology_term=ECO:0000255
TgeneSYNE1chr10:20290915chr6:152793548ENST000004131861131314_8666450.01444.0Coiled coilOntology_term=ECO:0000255
TgeneSYNE1chr10:20290915chr6:152793548ENST0000042306113146314_8666457.08750.0Coiled coilOntology_term=ECO:0000255
TgeneSYNE1chr10:20290915chr6:152793548ENST000003672531136178_283450.01726.0DomainCalponin-homology (CH) 2
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367253113627_134450.01726.0DomainCalponin-homology (CH) 1
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725513146178_283450.08798.0DomainCalponin-homology (CH) 2
TgeneSYNE1chr10:20290915chr6:152793548ENST000003672551314627_134450.08798.0DomainCalponin-homology (CH) 1
TgeneSYNE1chr10:20290915chr6:152793548ENST000004131861131178_283450.01444.0DomainCalponin-homology (CH) 2
TgeneSYNE1chr10:20290915chr6:152793548ENST00000413186113127_134450.01444.0DomainCalponin-homology (CH) 1
TgeneSYNE1chr10:20290915chr6:152793548ENST0000042306113146178_283457.08750.0DomainCalponin-homology (CH) 2
TgeneSYNE1chr10:20290915chr6:152793548ENST000004230611314627_134457.08750.0DomainCalponin-homology (CH) 1
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311361_289450.01726.0RegionNote=Actin-binding
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131461_289450.08798.0RegionNote=Actin-binding
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611311_289450.01444.0RegionNote=Actin-binding
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131461_289457.08750.0RegionNote=Actin-binding
TgeneSYNE1chr10:20290915chr6:152793548ENST000003672531136314_397450.01726.0RepeatNote=Spectrin 1
TgeneSYNE1chr10:20290915chr6:152793548ENST000003672531136398_502450.01726.0RepeatNote=Spectrin 2
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725513146314_397450.08798.0RepeatNote=Spectrin 1
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725513146398_502450.08798.0RepeatNote=Spectrin 2
TgeneSYNE1chr10:20290915chr6:152793548ENST000004131861131314_397450.01444.0RepeatNote=Spectrin 1
TgeneSYNE1chr10:20290915chr6:152793548ENST000004131861131398_502450.01444.0RepeatNote=Spectrin 2
TgeneSYNE1chr10:20290915chr6:152793548ENST0000042306113146314_397457.08750.0RepeatNote=Spectrin 1
TgeneSYNE1chr10:20290915chr6:152793548ENST0000042306113146398_502457.08750.0RepeatNote=Spectrin 2
TgeneSYNE1chr10:20290915chr6:152793548ENST0000036725311361_8746450.01726.0Topological domainCytoplasmic
TgeneSYNE1chr10:20290915chr6:152793548ENST00000367255131461_8746450.08798.0Topological domainCytoplasmic
TgeneSYNE1chr10:20290915chr6:152793548ENST0000041318611311_8746450.01444.0Topological domainCytoplasmic
TgeneSYNE1chr10:20290915chr6:152793548ENST00000423061131461_8746457.08750.0Topological domainCytoplasmic


Top

Fusion Gene Sequence for PLXDC2-SYNE1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000377242_ENST00000367255_TCGA-A8-A07R-01A_PLXDC2_chr10_20290915_+_SYNE1_chr6_152793548_length(transcript)=26961nt_BP=1165nt
GGCGACGGCAGCGCCTCCTCCGCCACCAAACTCCTGGGGCTCCGCGGGGGCTTGGGGCCACCTCCTCCTGAGCCCGGAGGAACCCTCTCC
CGATAGGTTCCAGCGTGACTCCCTCCCACTCCACCCTTTTCCTTTCTTCTTCCTCTTTTTTTTTTTTTTTTTTAAACACATTTTTTTCCT
GGCTTCGGACCTCAGACTGCTGCAGCCCTAACCTTCCCAGGGCTCAGCTCTTTGGAGCTGCCCATTCCTCCGGCTGCGAGAAAGGACGCG
CGCCCTGCGTCGGGCGAAGAAAAGAAGCAAAACTTGTCGGGAGGGTTTCGTCATCAACCTCCTTCCCGCAAACCTAAACCTCCTGCCGGG
GCCATCCCTAGACAGAGGAAAGTTCCTGCAGAGCCGACCAGCCCTAGTGGATCTGGGGCAGGCAGCGGCGCTGGCTGTGGAATTAGATCT
GTTTTGAACCCAGTGGAGCGCATCGCTGGGGCTCGGAAGTCACCGTCCGCGGGCACCGGGTTGGCGCTGCCCGAGTGGAACCGACAGTTT
GCGAGCCTCGGCTGCAAGTGGCCTCTCCTCCCCGCGGTTGTTGTTCAGTGTCGGGTGAGGGCTGCGAGTGTGGCAAGTTGCAAAGAGAGC
CTCAGAGGTCCGAAGAGCGCTGCGCTCCTACTCGCGTTCGCTTCTTCCTCTTCTCGGTTCCCTACTGTGAAATCGCAGCGACATTTACAA
AGGCCTCCGGGTCCTACCGAGACCGATCCGCAGCGTTTGGCCCGGTCGTGCCTATTGCATCGGGAGCCCCCGAGCACCGGCGAAGGACTG
GCGGGTGGGGTAGGGAGGTGGCGGCGGCGGCATGGCGAGGTTCCCGAAGGCCGACCTGGCCGCTGCAGGAGTTATGTTACTTTGCCACTT
CTTCACGGACCAGTTTCAGTTCGCCGATGGGAAACCCGGAGACCAAATCCTTGATTGGCAGTATGGAGTTACTCAGGCCTTCCCTCACAC
AGAGGAGGAGGTGGAAGTTGATTCACACGCGTACAGCCACAGGTGGAAAAGAAACTTGGACTTTCTCAAGGCGGTAGACACGAACCGAGC
AAGCGTCGGCCAAGACTCTCCTGAGCCCAGAAGCTTCACAGACCTGCTGCTGGATGATGGGCAGGACAATAACACTCAGATCGAGGATCT
GCTTCAAAACACGGATGCCCACAAAAGAGCATTCCATGAAATCTACCGGACCAGGTCTGTTAACGGGATTCCAGTGCCACCTGATCAATT
AGAGGACATGGCCGAGAGGTTTCATTTTGTTTCCTCCACATCAGAGCTACACCTAATGAAAATGGAATTTTTAGAATTAAAGTACCGTCT
GCTCTCACTGCTGGTTCTTGCAGAGTCAAAGCTGAAGTCTTGGATCATTAAGTACGGGAGGAGAGAGTCAGTGGAGCAGCTTCTACAAAA
CTACGTGTCTTTTATAGAAAATAGCAAGTTCTTTGAACAATATGAGGTGACATACCAGATCTTGAAACAGACAGCTGAGATGTATGTCAA
AGCAGATGGTTCAGTGGAAGAAGCTGAGAATGTGATGAAATTCATGAATGAAACCACCGCTCAGTGGAGGAATCTCTCAGTAGAAGTGAG
GAGTGTGAGGAGCATGCTGGAAGAAGTGATCTCTAACTGGGATCGCTATGGCAATACAGTGGCTAGTCTGCAAGCCTGGCTAGAGGATGC
TGAAAAAATGCTCAATCAATCAGAAAATGCCAAAAAGGATTTTTTTCGAAATTTACCTCATTGGATTCAGCAGCATACTGCCATGAACGA
TGCTGGCAATTTTCTAATTGAAACCTGTGATGAGATGGTTTCCCGTGACCTGAAGCAGCAATTACTGTTGCTAAATGGGCGGTGGAGGGA
GTTGTTTATGGAAGTCAAGCAATATGCTCAAGCTGATGAGATGGACAGAATGAAGAAGGAATACACAGACTGTGTTGTTACCCTGTCTGC
TTTTGCAACGGAAGCCCATAAGAAACTTTCTGAACCCTTAGAAGTCTCTTTTATGAATGTCAAGCTATTAATTCAAGACTTGGAGGATAT
TGAGCAGAGGGTGCCTGTGATGGATGCCCAATACAAGATAATTACAAAGACAGCACACCTCATTACCAAAGAAAGCCCCCAAGAAGAAGG
AAAAGAAATGTTTGCGACCATGTCAAAGCTCAAAGAGCAGCTAACCAAGGTCAAAGAATGTTACTCCCCACTCCTTTATGAGTCTCAGCA
GCTGTTGATTCCGTTGGAGGAATTAGAAAAGCAGATGACGTCCTTTTATGACTCACTTGGGAAAATCAATGAAATTATCACAGTTCTTGA
GCGTGAGGCACAATCGAGTGCCCTTTTTAAACAAAAACATCAGGAACTGTTAGCTTGTCAAGAAAACTGTAAGAAAACCTTGACACTTAT
TGAGAAAGGCAGTCAAAGTGTTCAAAAGTTTGTGACCTTGAGCAACGTGTTAAAGCATTTTGATCAGACGAGGCTACAAAGACAGATTGC
AGATATTCATGTTGCTTTTCAGAGTATGGTAAAGAAAACTGGAGATTGGAAGAAGCATGTGGAAACCAACAGTCGCTTGATGAAGAAGTT
TGAGGAGTCTCGAGCAGAGTTGGAGAAGGTACTGCGGATTGCTCAGGAGGGCCTGGAGGAAAAGGGGGATCCAGAGGAGCTCCTGCGGAG
ACACACTGAGTTTTTCAGTCAGCTGGATCAGAGGGTGCTCAATGCTTTCCTGAAAGCTTGTGATGAACTCACCGACATCCTTCCAGAGCA
GGAGCAGCAGGGGCTGCAGGAAGCTGTTCGAAAGCTCCACAAACAATGGAAGGATCTTCAAGGAGAAGCCCCTTATCATTTGCTTCATCT
GAAGATTGATGTGGAGAAGAATAGGTTCTTAGCCTCTGTAGAAGAATGCAGAACTGAGCTGGATCGAGAGACCAAGCTGATGCCCCAGGA
AGGCAGTGAAAAGATAATTAAAGAGCACAGGGTTTTCTTCAGTGACAAAGGTCCTCATCATCTCTGTGAGAAAAGGTTACAGCTCATCGA
GGAACTCTGTGTGAAACTCCCAGTGCGGGACCCAGTAAGGGACACACCTGGAACCTGTCACGTGACTCTCAAAGAGCTCAGAGCTGCCAT
TGACAGCACCTACAGGAAGCTCATGGAAGACCCAGACAAGTGGAAGGACTACACTAGCAGATTCTCTGAGTTCTCATCTTGGATATCTAC
AAATGAGACACAATTAAAGGGGATCAAGGGTGAGGCCATCGATACTGCCAACCACGGAGAGGTTAAACGTGCCGTTGAAGAGATCAGAAA
TGGTGTTACCAAAAGGGGTGAGACCCTCAGCTGGCTGAAATCCAGGCTGAAAGTTTTGACAGAAGTTTCTTCTGAGAATGAAGCCCAAAA
GCAGGGAGATGAGCTGGCAAAATTATCCAGCTCTTTCAAGGCTCTTGTGACGCTGCTGTCAGAGGTTGAAAAGATGCTAAGCAATTTTGG
GGACTGTGTCCAGTACAAAGAAATAGTCAAAAATTCTCTCGAAGAATTAATTTCTGGCTCTAAAGAAGTCCAGGAACAAGCTGAGAAGAT
CTTGGATACTGAAAATCTGTTTGAAGCACAGCAGTTACTTCTTCATCACCAGCAAAAGACAAAGCGGATCTCAGCAAAGAAGAGAGATGT
GCAGCAGCAGATCGCGCAGGCGCAGCAGGGAGAAGGGGGGCTGCCTGACCGAGGCCACGAGGAGCTGCGGAAGCTGGAGAGCACACTGGA
TGGCCTGGAGCGCAGCCGGGAGAGGCAGGAACGCCGCATCCAGGTCACATTAAGAAAATGGGAGCGATTTGAAACAAACAAAGAAACAGT
AGTAAGATACCTTTTTCAAACAGGTTCCAGTCATGAACGCTTCTTGAGTTTTAGCAGTTTGGAAAGTTTATCTTCAGAACTGGAACAAAC
AAAGGAGTTTTCTAAACGGACAGAAAGTATTGCAGTCCAGGCTGAGAACCTTGTAAAGGAAGCTTCAGAGATACCGCTTGGGCCCCAAAA
TAAGCAGCTGCTTCAACAGCAGGCCAAGTCAATCAAAGAACAAGTCAAAAAATTAGAAGACACGCTTGAAGAAGATATTAAAACCATGGA
AATGGTGAAAACCAAGTGGGATCATTTTGGCAGTAATTTTGAGACTCTGTCCGTCTGGATAACTGAGAAAGAAAAAGAACTCAATGCCTT
GGAAACTTCGTCATCTGCCATGGACATGCAAATCAGCCAAATTAAGGTCACAATTCAGGAAATAGAAAGTAAGCTCAGCAGCATTGTAGG
ATTAGAAGAAGAAGCCCAGTCTTTTGCTCAGTTTGTTACCACTGGAGAATCTGCTCGAATTAAAGCCAAGTTGACACAAATAAGAAGATA
CGGGGAAGAGCTTCGAGAGCATGCACAGTGTCTGGAAGGAACAATCCTGGGACATTTATCTCAGCAGCAAAAGTTTGAAGAGAACCTTAG
AAAGATCCAGCAATCTGTGTCTGAATTTGAAGATAAACTTGCTGTTCCAATTAAAATATGTTCTTCAGCTACAGAAACATACAAAGTTCT
TCAAGAACATATGGATCTCTGCCAGGCCCTGGAGTCACTGAGCAGCGCGATCACTGCCTTCTCAGCCAGTGCCAGGAAGGTTGTGAACAG
AGATTCCTGTGTTCAGGAGGCTGCGGCTCTACAGCAGCAATACGAGGACATCCTAAGGAGGGCGAAGGAGAGACAGACGGCGCTGGAGAA
TCTGCTGGCCCACTGGCAGAGGCTAGAGAAAGAACTATCATCCTTTTTGACCTGGTTAGAGCGGGGTGAAGCTAAAGCCAGTTCCCCAGA
AATGGACATTTCTGCAGACAGAGTCAAAGTGGAAGGTGAACTTCAGTTAATACAGGCACTGCAAAATGAAGTTGTATCCCAGGCCTCATT
CTATAGCAAACTTTTGCAATTGAAGGAATCATTGTTCTCAGTAGCCTCCAAAGATGATGTGAAAATGATGAAACTACATTTGGAGCAGTT
GGATGAGAGATGGAGAGATTTACCACAGATCATTAACAAAAGGATTAATTTTCTTCAGTCTGTGGTTGCTGAACACCAGCAATTTGATGA
GCTGCTGCTTTCCTTTTCTGTCTGGATTAAACTGTTTCTCAGTGAATTACAAACTACCTCTGAGATTAGCATAATGGACCATCAAGTAGC
CCTTACTCGGCATAAGGACCACGCAGCAGAAGTAGAGAGCAAAAAGGGCGAATTGCAGAGTCTGCAGGGTCACTTAGCAAAGTTGGGTTC
TCTGGGCCGTGCTGAGGACCTCCACCTCCTGCAGGGAAAGGCTGAGGACTGCTTCCAGCTGTTTGAGGAGGCCAGCCAGGTTGTGGAGAG
GCGGCAGCTTGCCCTGTCCCATTTGGCAGAATTCCTCCAGAGCCATGCCTCTCTGTCCGGCATTCTCCGCCAGCTGAGGCAAACAGTGGA
AGCAACCAACAGTATGAATAAGAACGAGTCTGATTTGATAGAAAAGGACCTCAATGATGCTCTTCAAAATGCTAAAGCATTAGAATCTGC
TGCCGTCAGTCTGGATGGCATTCTTTCCAAAGCCCAATACCATCTGAAAATCGGGAGCTCTGAGCAAAGGACTTCCTGCAGAGCCACGGC
TGATCAGCTCTGTGGAGAGGTAGAGAGGATCCAGAACCTTCTGGGAACCAAGCAGAGTGAGGCAGATGCTCTGGCAGTGTTGAAAAAAGC
ATTCCAAGACCAGAAAGAGGAGCTTCTGAAAAGCATTGAGGACATTGAAGAAAGGACTGACAAAGAGCGATTGAAAGAACCTACCCGCCA
AGCTCTTCAGCAGAGGTTAAGAGTGTTTAATCAGCTAGAAGATGAATTGAATTCTCACGAGCATGAACTATGTTGGTTGAAAGACAAAGC
CAAGCAAATTGCCCAGAAAGATGTAGCTTTTGCACCTGAAGTTGACAGGGAGATAAACCGCTTAGAGGTCACCTGGGATGATACCAAAAG
ACTAATTCATGAAAATCAGGGTCAGTGCTGTGGACTTATTGACTTAATGAGAGAATATCAGAACCTGAAATCAGCTGTATCTAAAGTCTT
AGAAAATGCCAGCAGTGTGATTGTAACCAGAACTACCATAAAAGATCAGGAGGATCTTAAATGGGCTTTTTCCAAGCATGAAACTGCCAA
GAACAAAATGAATTACAAACAGAAAGACTTGGATAACTTTACCAGCAAAGGAAAACACTTGTTATCTGAGCTGAAGAAAATTCACAGTAG
TGATTTCAGCTTGGTGAAAACAGACATGGAGAGCACCGTGGACAAATGGCTGGATGTATCAGAGAAACTTGAAGAAAACATGGATAGGCT
GAGAGTAAGCCTGTCCATTTGGGATGATGTACTGTCAACTAGAGATGAGATTGAGGGATGGTCAAACAACTGCGTTCCACAGATGGCAGA
AAACATCAGCAACCTGGATAACCACCTCAGAGCTGAAGAACTGCTTAAAGAATTTGAGTCTGAAGTTAAAAACAAAGCATTGAGATTGGA
AGAACTGCATTCCAAAGTTAATGATCTGAAAGAATTAACTAAAAATCTAGAAACACCGCCAGACCTTCAGTTTATAGAAGCAGACTTAAT
GCAGAAACTGGAGCATGCCAAAGAAATAACTGAAGTAGCAAAAGGAACCCTGAAGGATTTCACGGCTCAAAGTACACAAGTGGAGAAGTT
TATTAATGACATAACAACATGGTTCACAAAAGTGGAAGAATCGTTGATGAACTGTGCCCAAAATGAGACTTGTGAAGCATTGAAAAAAGT
CAAGGATATACAAAAAGAACTTCAAAGTCAACAAAGCAACATCAGCTCTACCCAAGAAAATCTCAATAGCTTGTGCCGCAAGTACCACTC
AGCTGAGTTGGAGAGCCTGGGCCGTGCAATGACTGGTCTGATAAAGAAACATGAAGCCGTGAGCCAGTTGTGCTCCAAAACCCAGGCCAG
CCTGCAGGAATCTCTGGAAAAACACTTCAGTGAGTCTATGCAGGAATTCCAAGAATGGTTTTTGGGAGCAAAGGCAGCAGCAAAAGAATC
ATCAGATCGCACCGGTGACAGCAAAGTTCTAGAAGCAAAGCTCCATGATCTTCAGAACATTTTGGACTCAGTCAGTGATGGGCAGAGCAA
ACTTGATGCAGTGACTCAAGAAGGACAAACTTTGTATGCACATTTGTCTAAACAAATTGTCAGTAGCATTCAAGAACAAATCACAAAGGC
CAATGAAGAGTTTCAAGCATTTCTGAAACAATGCCTTAAAGATAAGCAGGCTCTTCAAGACTGTGCTTCAGAACTTGGAAGCTTTGAAGA
TCAGCACAGAAAACTGAACTTATGGATCCATGAAATGGAAGAAAGGTTCAATACGGAAAACTTGGGAGAGAGTAAACAGCACATTCCTGA
GAAGAAAAATGAAGTTCATAAAGTTGAAATGTTTTTGGGAGAACTGCTGGCTGCAAGAGAGTCTCTTGATAAGCTTTCCCAGAGAGGGCA
GCTTCTGAGTGAAGAAGGCCACGGTGCTGGGCAGGAGGGCCGCCTGTGTTCCCAGCTCCTCACAAGCCACCAGAACCTACTTAGAATGAC
CAAAGAGAAACTCCGGAGCTGCCAGGTGGCCCTTCAGGAGCACGAAGCCCTGGAGGAAGCACTGCAAAGCATGTGGTTCTGGGTGAAGGC
CATTCAGGACAGACTGGCCTGTGCAGAGAGCACTCTTGGGAGCAAAGACACCCTGGAGAAACGGCTGTCACAAATACAGGATATTCTCCT
GATGAAAGGTGAAGGGGAAGTTAAGTTGAATATGGCCATTGGCAAGGGGGAACAGGCCTTGAGAAGTAGCAACAAAGAAGGTCAGAGGGT
GATTCAGACTCAGTTAGAGACCCTTAAAGAAGTGTGGGCTGACATCATGAGCTCCTCCGTCCACGCTCAAAGCACTTTAGAGTCTGTGAT
TAGCCAATGGAATGACTATGTAGAGAGGAAAAACCAGTTGGAGCAGTGGATGGAATCAGTGGATCAAAAAATAGAACATCCCTTACAACC
ACAGCCAGGTCTGAAAGAGAAGTTCGTCCTGCTTGACCACCTCCAGTCCATCCTGTCTGAGGCAGAAGATCACACGAGAGCCCTTCACCG
TCTAATTGCGAAGTCCAGGGAGCTCTACGAAAAGACAGAGGATGAGTCTTTCAAGGACACAGCTCAAGAGGAGCTGAAAACACAGTTTAA
TGATATAATGACTGTTGCCAAGGAAAAAATGAGGAAAGTGGAAGAGATTGTGAAAGATCATCTAATGTATTTAGATGCGGTCCACGAGTT
CACAGATTGGCTCCATTCAGCAAAGGAAGAACTTCACCGGTGGTCAGATATGTCTGGAGATTCATCAGCCACCCAGAAAAAGTTATCAAA
AATTAAGGAGCTGATAGATTCCAGAGAGATTGGTGCAAGCCGTCTCAGCAGAGTGGAGTCGCTGGCTCCCGAAGTGAAACAGAACACAAC
TGCCAGTGGGTGTGAGCTCATGCACACGGAGATGCAGGCCCTGCGTGCCGACTGGAAGCAGTGGGAAGACAGTGTATTCCAAACGCAGAG
CTGTTTGGAGAACCTGGTCAGCCAGATGGCCCTTTCGGAGCAGGAATTCTCAGGCCAAGTGGCTCAACTGGAGCAGGCCCTGGAACAGTT
CAGTGCCCTTCTGAAAACCTGGGCTCAGCAGTTAACCCTCCTGGAAGGCAAGAACACGGATGAGGAGATAGTGGAATGCTGGCACAAAGG
ACAAGAGATACTGGATGCTTTGCAAAAAGCAGAGCCTAGAACAGAGGATCTCAAGTCTCAGCTGAATGAACTTTGTCGATTTTCCAGAGA
CCTGAGTACCTACAGTGGAAAAGTTTCTGGCTTGATTAAAGAGTATAATTGTCTTTGTTTGCAAGCATCCAAGGGCTGCCAGAATAAAGA
ACAGATTTTACAGCAAAGATTTCGAAAGGCCTTCAGGGATTTCCAGCAGTGGTTGGTTAATGCAAAAATCACTACCGCCAAGTGTTTTGA
TATACCTCAAAATATAAGTGAAGTTTCAACTAGTCTTCAGAAAATACAGGAGTTTTTGTCAGAAAGTGAAAATGGACAGCACAAGCTAAA
CATGATGCTGTCTAAAGGGGAACTTCTGAGTACCCTGCTGACCAAAGAGAAAGCGAAAGGGATCCAGGCCAAAGTTACAGCTGCAAAAGA
AGATTGGAAAAATTTTCATTCAAATCTCCACCAAAAAGAATCTGCTCTAGAGAATCTAAAGATCCAAATGAAGGACTTTGAAGTAAGTGC
TGAGCCTATCCAGGACTGGCTGAGTAAAACTGAGAAGATGGTCCATGAAAGCAGCAATCGCCTCTATGATCTGCCAGCAAAGAGGAGGGA
GCAGCAGAAGCTCCAGTCTGTCCTTGAGGAAATACACTGCTACGAGCCTCAGCTCAACAGGCTGAAAGAGAAAGCTCAGCAGCTGTGGGA
AGGACAAGCTGCCAGCAAGAGCTTTAGGCACAGAGTGTCGCAGCTGTCTTCTCAGTATCTAGCGCTAAGCAATTTAACAAAGGAGAAAGT
GTCAAGACTGGATAGAATCGTTGCAGAACACAATCAGTTCTCTCTTGGGATTAAAGAATTACAAGACTGGATGACGGATGCGATTCACAT
GCTGGATTCATACTGCCACCCGACATCCGACAAAAGTGTGCTGGACAGCAGGACGCTCAAGCTCGAGGCTCTATTATCAGTCAAACAGGA
AAAAGAGATTCAGATGAAAATGATAGTGACCAGGGGAGAATCTGTCCTTCAGAATACTTCTCCAGAAGGCATTCCCACTATTCAGCAGCA
GCTGCAGAGTGTGAAGGATATGTGGGCATCCCTTTTGTCTGCAGGGATTCGTTGTAAAAGCCAACTCGAAGGAGCTCTCTCCAAGTGGAC
AAGTTATCAGGATGGCGTTCGACAGTTCTCCGGTTGGATGGATAGTATGGAAGCCAACCTGAATGAATCAGAAAGGCAGCATGCGGAGCT
GCGGGATAAAACAACGATGCTCGGAAAAGCCAAGTTATTAAATGAAGAAGTGCTGAGTTACAGCAGCTTGCTGGAGACCATCGAAGTCAA
AGGGGCTGGCATGACAGAACACTATGTCACCCAGCTAGAACTCCAGGATCTACAGGAACGATACAGAGCCATCCAAGAGAGGGCCAAGGA
AGCCGTAACCAAGTCTGAAAAACTTGTCCGCCTGCACCAAGAGTATCAGAGAGACCTAAAGGCATTTGAAGTTTGGTTGGGGCAAGAACA
AGAAAAGCTCGACCAGTATTCAGTTCTTGAAGGTGATGCCCACACTCATGAGACAACATTGCGTGATCTTCAGGAGCTACAGGTACACTG
TGCAGAGGGGCAGGCCCTGTTGAACTCAGTGCTGCACACCAGAGAGGATGTGATCCCATCAGGTATCCCACAGGCAGAGGACCGGGCTTT
AGAGTCTCTCCGGCAAGACTGGCAGGCTTACCAGCACAGGCTGTCCGAGACTCGAACTCAGTTCAATAACGTGGTGAACAAATTGAGGCT
AATGGAGCAAAAGTTTCAGCAAGTAGATGAATGGCTCAAAACAGCAGAGGAGAAAGTTAGTCCCAGGACCAGACGTCAGTCTAACAGGGC
AACCAAGGAGATACAATTACATCAGATGAAGAAGTGGCACGAAGAAGTGACTGCATACAGAGATGAAGTTGAGGAAGTGGGAGCTAGAGC
TCAGGAGATACTGGACGAGAGCCACGTGAACAGCAGAATGGGTTGCCAGGCCACCCAGCTGACTTCCAGATACCAGGCCCTGCTTCTCCA
AGTGCTGGAACAAATAAAATTCCTGGAGGAGGAGATTCAGAGTTTGGAGGAATCAGAATCATCCCTCAGTTCCTATTCTGATTGGTATGG
CTCTACTCATAAAAACTTCAAGAATGTGGCTACCAAGATTGACAAAGTAGATACAGTAATGATGGGGAAGAAATTGAAGACGTTGGAGGT
TTTGCTCAAAGACATGGAGAAAGGTCACAGTTTGCTGAAATCAGCCCGGGAGAAAGGAGAGAGGGCTGTTAAATACTTGGAGGAAGGCGA
GGCAGAGAGGTTAAGAAAGGAGATTCATGATCACATGGAGCAGTTGAAGGAACTGACCAGCACTGTCCGGAAAGAACACATGACGCTGGA
AAAAGGTCTTCATTTAGCAAAGGAATTCTCAGATAAATGCAAAGCACTGACACAGTGGATAGCAGAATACCAGGAAATTCTACATGTTCC
TGAAGAACCCAAAATGGAATTATATGAGAAAAAAGCTCAGTTATCTAAATACAAGTCACTTCAACAAACGGTGCTGTCCCATGAACCATC
AGTAAAGTCAGTGAGAGAGAAGGGTGAAGCTCTTTTGGAACTGGTGCAGGACGTCACTTTAAAGGACAAAATAGATCAACTTCAAAGTGA
TTACCAGGACCTGTGCAGCATAGGAAAGGAGCATGTCTTCAGTCTGGAGGCGAAAGTCAAAGACCATGAAGACTACAACAGTGAGCTCCA
AGAGGTCGAAAAGTGGCTGCTGCAGATGTCTGGCAGACTGGTGGCACCTGACCTCCTGGAGACAAGCAGCCTGGAGACAATCACCCAGCA
ATTGGCCCACCACAAGGCAATGATGGAAGAAATTGCTGGTTTTGAAGACCGTTTGAACAATCTTCAAATGAAAGGTGATACTTTGATTGG
CCAATGTGCAGACCACCTGCAAGCGAAACTTAAACAAAACGTGCATGCTCATCTGCAGGGCACAAAGGACAGCTACTCAGCGATCTGCAG
CACAGCTCAGAGGATGTACCAGAGTTTGGAACACGAACTTCAGAAGCACGTCAGCCGACAAGACACCCTGCAGCAGTGCCAGGCCTGGCT
TTCTGCAGTCCAGCCGGATTTAGAGCCAAGTCCTCAACCACCTCTTAGTAGGGCAGAAGCCATTAAGCAGGTCAAACACTTCAGAGCTTT
GCAAGAGCAGGCAAGGACCTACCTAGATCTCCTTTGCTCCATGTGTGACCTGTCAAATGCTTCGGTGAAAACCACAGCAAAAGACATTCA
ACAAACAGAGCAAACGATTGAACAAAAGCTTGTCCAGGCCCAGAACTTAACTCAGGGCTGGGAAGAGATCAAGCACCTGAAGTCTGAGCT
CTGGATTTACCTGCAAGATGCTGATCAGCAACTGCAGAACATGAAGAGGAGGCACTCTGAGCTGGAGCTGAACATTGCACAGAACATGGT
TTCACAAGTTAAGGATTTTGTTAAGAAACTACAGAGCAAACAGGCATCCGTGAACACCATAATAGAAAAGGTGAATAAGTTAACAAAGAA
GGAGGAATCGCCTGAACACAAGGAAATAAATCATTTAAATGATCAGTGGCTCGATTTGTGCCGTCAGTCTAACAACCTGTGCTTGCAAAG
GGAAGAGGATCTTCAGAGAACAAGAGATTACCATGACTGTATGAATGTTGTTGAAGTGTTCCTAGAAAAATTTACTACAGAATGGGATAA
CTTGGCCAGATCTGATGCAGAGAGTACAGCTGTCCACCTGGAAGCTTTGAAAAAGTTAGCATTGGCATTGCAGGAGAGAAAGTATGCTAT
TGAAGATCTGAAAGATCAAAAGCAGAAAATGATAGAGCATCTGAATTTAGATGACAAGGAGTTAGTCAAAGAACAGACGAGTCATTTAGA
GCAACGTTGGTTTCAGCTTGAGGACCTCATTAAAAGGAAAATCCAAGTGTCAGTCACCAACTTGGAGGAGTTAAATGTGGTGCAGTCCAG
ATTTCAGGAGCTAATGGAGTGGGCAGAAGAGCAACAACCCAACATCGCCGAGGCCCTTAAGCAGAGCCCTCCTCCAGATATGGCTCAGAA
CCTTCTCATGGATCACCTGGCCATCTGCAGTGAACTGGAGGCCAAGCAGATGCTCCTGAAATCGCTTATAAAGGACGCAGACAGGGTCAT
GGCAGATCTTGGTCTCAATGAGCGACAGGTCATCCAGAAGGCTCTCTCTGATGCACAAAGCCACGTGAATTGTCTCAGTGACTTAGTGGG
CCAGCGAAGAAAGTACTTAAACAAAGCCTTGTCCGAGAAAACCCAGTTTCTCATGGCAGTGTTCCAGGCCACCAGCCAAATTCAGCAACA
TGAGCGAAAGATAATGTTCCGTGAACACATCTGTCTGTTACCAGATGATGTGAGCAAACAAGTCAAAACATGTAAGAGTGCACAAGCCAG
CCTCAAGACTTACCAAAATGAAGTCACTGGACTTTGGGCCCAGGGTCGCGAACTAATGAAGGAAGTCACAGAGCAGGAAAAGAGTGAAGT
GCTGGGGAAGCTTCAGGAATTGCAGAGTGTCTATGACAGTGTTTTACAAAAGTGCAGTCACCGGTTACAAGAACTAGAGAAGAATTTGGT
TTCTAGGAAGCATTTTAAGGAAGATTTTGATAAAGCTTGCCACTGGCTAAAACAAGCAGATATTGTTACATTTCCTGAAATCAACCTAAT
GAATGAGAGTTCTGAGCTTCATACACAACTGGCTAAATACCAAAACATTCTTGAACAATCTCCAGAATATGAAAATCTTCTACTTACGCT
GCAGAGAACTGGGCAGACCATATTACCATCGCTGAATGAAGTCGATCATTCCTACCTCAGTGAAAAGCTAAATGCTTTGCCTCGACAATT
TAATGTAATTGTTGCCTTGGCTAAAGACAAGTTCTATAAAGTCCAGGAAGCAATTCTTGCTCGGAAGGAATATGCTTCCTTGATTGAGTT
GACAACCCAGTCTCTGAGTGAACTTGAAGCCCAATTCTTGAGGATGAGCAAAGTTCCCACCGACCTGGCCGTTGAGGAGGCTCTTTCTCT
GCAAGATGGTTGCAGAGCCATTCTGGACGAGGTGGCGGGCCTTGGGGAGGCGGTGGATGAACTGAACCAGAAAAAAGAAGGTTTTCGCAG
CACAGGTCAGCCTTGGCAGCCAGACAAGATGCTGCACCTTGTCACCTTATATCACAGGCTGAAGCGACAAACAGAACAGAGGGTTAGCTT
ATTAGAAGACACCACCAGTGCTTACCAAGAACACGAGAAGATGTGCCAACAGCTGGAGAGACAACTGAAGTCTGTAAAAGAGGAGCAGTC
CAAAGTGAATGAGGAAACGCTGCCTGCAGAGGAGAAGCTCAAAATGTATCACTCCCTGGCAGGAAGTCTCCAGGACTCAGGGATTGTACT
GAAACGAGTAACCATACATCTTGAAGATCTTGCCCCACACCTTGACCCCTTGGCTTATGAGAAAGCCAGGCATCAGATCCAGTCCTGGCA
AGGGGAGTTAAAACTGTTGACTTCTGCCATTGGTGAGACGGTGACAGAATGTGAGAGCCGAATGGTGCAGAGTATAGACTTCCAGACTGA
GATGAGTCGCTCCCTGGACTGGCTGAGGAGAGTGAAGGCAGAGCTCAGTGGGCCGGTGTACCTAGACCTCAACCTGCAGGACATCCAAGA
GGAAATCAGAAAAATCCAAATTCATCAGGAAGAGGTCCAGTCCAGCTTGAGAATCATGAATGCGCTGAGTCACAAGGAAAAGGAGAAGTT
CACAAAGGCCAAGGAGCTGATTTCTGCGGATTTAGAACACAGCCTCGCTGAGCTCTCAGAGCTGGATGGAGACATCCAGGAAGCCTTACG
CACCAGACAGGCTACCTTGACTGAAATATATAGCCAGTGTCAAAGGTATTATCAGGTATTTCAAGCAGCCAATGACTGGCTTGAGGATGC
CCAAGAATTGTTACAGCTGGCAGGCAATGGCCTAGACGTGGAGAGCGCAGAGGAAAATCTCAAAAGCCACATGGAATTTTTCAGTACAGA
GGATCAGTTCCATAGTAACCTGGAGGAGCTCCACAGCCTGGTAGCCACCCTGGACCCACTCATCAAGCCAACCGGCAAAGAAGACCTAGA
ACAGAAAGTGGCTTCTCTGGAACTCAGGAGCCAGAGGATGAGCCGGGACTCTGGTGCCCAAGTGGATCTCTTGCAGAGATGCACAGCTCA
ATGGCACGATTACCAGAAAGCAAGGGAAGAGGTTATTGAATTGATGAATGATACAGAAAAGAAATTGTCTGAGTTTTCTTTGTTGAAGAC
TTCGTCTAGTCATGAAGCGGAAGAAAAATTGTCAGAACACAAGGCTTTAGTGTCAGTGGTTAACTCTTTCCATGAGAAAATTGTGGCCCT
TGAGGAAAAAGCTTCACAACTGGAGAAAACCGGAAATGATGCCAGCAAAGCCACCCTGAGCAGGTCAATGACCACCGTCTGGCAGCGCTG
GACACGCCTTCGAGCTGTGGCCCAGGACCAGGAGAAGATCCTGGAAGATGCAGTGGATGAGTGGACGGGCTTTAACAACAAGGTTAAAAA
GGCCACTGAAATGATTGATCAGCTGCAAGATAAGTTACCTGGAAGTTCAGCAGAGAAAGCATCGAAAGCAGAGCTCTTAACTCTTCTTGA
ATACCACGACACGTTCGTTCTGGAGCTGGAGCAGCAGCAGTCGGCCTTGGGCATGCTGCGGCAGCAAACCCTGAGCATGCTCCAGGATGG
AGCCGCCCCAACCCCTGGGGAAGAGCCTCCGCTCATGCAGGAAATCACCGCCATGCAAGATCGGTGCCTGAACATGCAGGAGAAAGTGAA
GACTAATGGAAAGTTGGTGAAGCAAGAGCTGAAGGACCGAGAAATGGTGGAGACTCAGATCAATTCTGTGAAATGTTGGGTTCAGGAAAC
GAAAGAATATTTAGGGAATCCAACAATAGAAATAGATGCTCAACTTGAAGAACTTCAGATTCTCCTAACAGAAGCCACAAATCACCGACA
GAACATTGAAAAAATGGCAGAAGAACAGAAGGAGAAGTACTTAGGTCTTTATACCATATTACCTTCTGAACTCTCCCTTCAGTTGGCTGA
AGTGGCGTTAGATCTAAAGATCCGAGATCAGATCCAAGACAAAATAAAAGAAGTTGAGCAGAGCAAGGCCACGAGCCAGGAACTCAGCCG
GCAAATTCAGAAGTTAGCTAAAGACCTCACAACTATTCTAACTAAGCTGAAAGCGAAGACAGATAATGTAGTTCAAGCTAAAACTGACCA
AAAGGTGCTGGGAGAGGAATTAGATGGCTGTAATTCAAAGTTAATGGAATTAGATGCAGCAGTACAGAAATTCTTGGAACAGAATGGCCA
ACTGGGTAAGCCACTGGCCAAGAAGATAGGAAAACTGACTGAACTTCACCAGCAGACCATTAGACAAGCTGAGAATCGGCTCTCCAAGCT
CAATCAGGCAGCATCACATTTAGAAGAATACAATGAAATGCTTGAATTAATTTTGAAGTGGATTGAAAAAGCTAAAGTCTTGGCTCATGG
AACTATTGCATGGAATTCTGCAAGCCAGCTTCGGGAACAATATATTTTGCATCAGACCCTGCTAGAAGAATCCAAAGAAATTGACAGTGA
GCTGGAAGCAATGACTGAGAAATTACAGTACCTCACTAGCGTGTACTGTACAGAAAAAATGTCTCAGCAAGTGGCAGAACTGGGACGGGA
GACTGAGGAGTTGCGACAGATGATCAAAATTCGTTTGCAGAACCTCCAAGATGCAGCTAAGGATATGAAAAAATTTGAAGCAGAGTTGAA
AAAGTTACAAGCTGCCTTGGAGCAAGCCCAGGCAACACTGACTTCTCCAGAAGTTGGACGTCTCAGTCTCAAGGAGCAGCTCTCTCATCG
GCAGCATTTGTTGTCTGAGATGGAGTCACTGAAGCCGAAGGTGCAAGCAGTGCAGCTCTGCCAGAGTGCCCTCCGGATCCCCGAGGATGT
GGTTGCCAGCTTACCTCTCTGTCATGCTGCTCTGCGGCTGCAGGAAGAGGCCAGCCGGCTGCAGCACACCGCCATCCAGCAGTGTAACAT
CATGCAGGAAGCTGTGGTACAATATGAACAATATGAGCAAGAAATGAAACATCTCCAGCAACTGATAGAAGGAGCTCACAGAGAGATTGA
GGATAAACCTGTTGCCACCAGTAACATACAGGAGCTGCAGGCTCAGATTTCTCGGCATGAGGAGCTGGCGCAGAAAATTAAGGGCTACCA
GGAGCAGATCGCTTCTTTGAATTCCAAGTGCAAGATGCTGACGATGAAAGCCAAGCACGCCACCATGCTGCTGACGGTGACCGAGGTCGA
GGGGCTGGCGGAAGGGACAGAGGACCTGGATGGGGAGCTCCTCCCCACGCCTTCGGCCCACCCCTCTGTGGTCATGATGACTGCAGGTCG
CTGTCACACTTTGCTGTCACCGGTCACTGAGGAGTCTGGGGAGGAGGGAACCAACAGTGAGATTTCCTCTCCACCTGCCTGTCGCTCCCC
TTCACCTGTGGCTAATACAGATGCTTCTGTTAACCAGGACATTGCATATTACCAAGCCTTGTCTGCTGAGAGGTTGCAGACAGATGCTGC
AAAAATTCACCCCAGCACATCCGCATCCCAGGAGTTCTATGAACCGGGATTGGAGCCATCCGCTACTGCCAAACTGGGTGATTTGCAGCG
TTCTTGGGAAACCTTAAAGAATGTGATCAGTGAGAAGCAGCGCACACTCTATGAAGCTTTGGAACGCCAGCAGAAGTACCAGGACTCCCT
CCAGTCCATCTCTACGAAGATGGAGGCCATTGAGCTGAAACTCAGTGAGAGCCCAGAGCCTGGCAGGAGTCCAGAAAGCCAGATGGCTGA
ACATCAGGCATTGATGGATGAGATTCTCATGCTCCAGGATGAAATCAATGAGCTCCAGTCCTCTCTCGCAGAGGAGCTGGTATCCGAGTC
TTGTGAGGCCGACCCTGCGGAGCAGCTGGCCTTGCAGTCCACGCTCACTGTCTTAGCCGAGCGAATGTCCACCATCAGGATGAAAGCCTC
GGGGAAACGGCAGCTTTTGGAGGAGAAGTTGAATGATCAGCTGGAGGAACAAAGGCAGGAACAGGCCCTGCAGAGGTATCGCTGTGAAGC
CGATGAGCTGGACAGCTGGCTCTTGAGTACCAAGGCCACTCTGGACACTGCGCTGAGTCCACCCAAGGAGCCCATGGACATGGAGGCCCA
GCTTATGGACTGCCAGAATATGCTGGTGGAAATAGAGCAGAAGGTGGTGGCTTTATCAGAACTGTCAGTCCACAATGAGAACCTGCTGCT
GGAGGGCAAAGCTCACACCAAGGACGAGGCCGAGCAGCTGGCTGGAAAGCTGAGAAGGCTCAAGGGGAGCCTGCTGGAGCTGCAGAGAGC
CCTGCATGATAAGCAGCTCAACATGCAGGGAACAGCACAGGAGAAGGAGGAGAGCGATGTTGACCTAACAGCCACGCAGAGCCCCGGCGT
CCAGGAATGGCTGGCCCAAGCTCGCACCACATGGACCCAGCAGCGGCAGAGCAGTCTCCAGCAACAAAAAGAGTTAGAACAGGAATTAGC
CGAGCAGAAGAGTCTCCTTCGCTCAGTAGCCAGTCGTGGAGAGGAGATTCTAATTCAACATTCGGCGGCAGAGACCTCTGGTGATGCTGG
CGAAAAACCTGATGTGTTATCCCAGGAGTTGGGGATGGAAGGGGAGAAATCATCCGCTGAAGACCAGATGAGAATGAAATGGGAAAGCCT
ACATCAAGAATTTAGTACCAAGCAGAAACTACTACAGAATGTTCTGGAACAGGAACAAGAGCAAGTGCTTTATAGCAGGCCAAATCGACT
CTTGTCTGGTGTGCCACTGTACAAAGGGGACGTGCCAACCCAAGATAAATCTGCAGTTACATCTTTGCTGGATGGACTGAACCAAGCCTT
CGAGGAGGTTTCATCCCAGAGTGGAGGGGCAAAGAGGCAGAGTATACACTTGGAGCAGAAGTTGTATGATGGAGTCTCAGCCACCTCTAC
TTGGTTGGATGACGTTGAAGAACGTTTATTTGTTGCCACAGCACTTTTACCAGAAGAAACAGAGACTTGTCTCTTCAACCAAGAGATTCT
TGCCAAAGACATTAAGGAAATGTCTGAAGAAATGGATAAGAACAAAAACTTGTTTTCCCAAGCTTTTCCAGAGAATGGTGATAATCGAGA
TGTTATTGAAGATACTTTGGGTTGTCTTTTGGGCAGGTTATCCTTGCTAGACTCAGTAGTGAATCAACGATGTCATCAGATGAAAGAAAG
ACTTCAGCAAATACTAAATTTCCAGAATGATCTGAAAGTGCTGTTTACATCACTGGCTGACAACAAATACATCATTCTGCAAAAACTGGC
AAATGTGTTTGAACAGCCCGTAGCAGAACAAATAGAGGCAATACAACAGGCTGAAGATGGACTCAAAGAATTTGATGCAGGAATCATTGA
ATTAAAGAGGCGTGGTGACAAGCTACAGGTCGAGCAGCCGTCCATGCAAGAACTCTCCAAGCTCCAGGACATGTATGATGAGCTGATGAT
GATCATTGGCTCCCGGAGGAGTGGTCTGAATCAGAACCTTACACTCAAGAGTCAGTATGAGAGGGCCCTACAAGATCTGGCTGACCTGCT
AGAAACTGGTCAGGAGAAGATGGCAGGAGACCAGAAAATCATCGTGTCTTCCAAAGAGGAAATCCAGCAACTACTTGACAAACATAAGGA
ATACTTTCAGGGCCTGGAATCTCATATGATCTTGACTGAAACACTCTTCAGAAAGATAATCAGCTTTGCAGTCCAAAAGGAAACCCAGTT
CCATACAGAGCTGATGGCTCAGGCTTCTGCTGTACTGAAACGGGCTCACAAGAGGGGTGTGGAGCTGGAGTACATTCTAGAGACGTGGTC
CCATCTGGATGAGGACCAGCAGGAGCTCAGCAGACAGCTGGAGGTGGTGGAAAGCAGCATCCCAAGCGTGGGTCTGGTGGAGGAGAACGA
GGACAGGCTTATTGACCGCATAACACTCTACCAGCATTTAAAATCTAGCCTTAATGAATACCAGCCCAAATTATATCAAGTATTAGATGA
TGGGAAACGACTTCTGATATCCATCAGCTGCTCAGATCTAGAAAGCCAACTAAATCAACTTGGAGAGTGCTGGCTAAGTAACACCAATAA
AATGTCTAAGGAACTTCACAGACTGGAAACAATATTGAAACACTGGACCAGATATCAAAGTGAATCTGCAGATCTAATTCACTGGTTACA
ATCTGCAAAAGACCGGCTAGAATTTTGGACTCAGCAATCTGTGACAGTCCCACAAGAGCTGGAAATGGTCCGTGATCATCTAAATGCTTT
CCTGGAGTTTTCTAAAGAAGTGGATGCCCAATCTTCCCTGAAATCATCTGTTCTGAGTACTGGAAATCAGCTCCTTCGACTAAAAAAGGT
GGACACAGCCACGCTGCGCTCTGAGCTGTCGCGCATTGATAGCCAGTGGACTGACCTGCTAACCAATATCCCAGCCGTCCAGGAGAAGCT
CCACCAGCTCCAGATGGATAAACTGCCTTCCCGCCATGCCATTTCTGAAGTCATGAGTTGGATTTCTCTAATGGAAAATGTTATTCAGAA
GGATGAAGATAATATTAAAAATTCCATAGGTTACAAGGCAATTCATGAATACCTTCAGAAATATAAGGGTTTTAAGATAGACATTAACTG
TAAACAGCTGACAGTGGATTTTGTGAACCAGTCCGTGCTACAAATCAGCAGTCAGGATGTGGAAAGTAAGCGTAGTGATAAGACTGATTT
TGCTGAGCAACTTGGAGCAATGAATAAAAGTTGGCAAATTCTGCAAGGTCTAGTAACTGAGAAGATCCAGCTGTTGGAAGGCTTATTGGA
ATCTTGGTCAGAATATGAAAATAATGTACAATGTCTGAAAACATGGTTTGAAACCCAGGAAAAGAGACTAAAACAACAGCATCGAATTGG
AGATCAGGCTTCTGTTCAAAATGCACTGAAAGACTGTCAGGATCTGGAAGATTTGATTAAAGCAAAAGAAAAAGAAGTAGAGAAAATTGA
GCAGAATGGACTTGCTTTGATTCAGAACAAGAAAGAAGACGTCTCTAGCATTGTCATGAGCACACTGCGAGAGCTCGGCCAAACCTGGGC
AAATTTAGATCACATGGTTGGACAATTAAAGATACTGCTGAAATCAGTGCTTGACCAATGGAGTAGTCACAAAGTGGCCTTTGACAAGAT
AAACAGTTACCTCATGGAGGCCAGATACTCTCTTTCCCGATTCCGTCTGCTGACTGGCTCCTTAGAAGCTGTGCAAGTTCAGGTGGACAA
TCTTCAGAATCTCCAAGATGATCTGGAAAAACAGGAAAGGAGCTTACAGAAATTTGGCTCTATCACCAACCAATTATTAAAAGAGTGTCA
CCCACCCGTGACAGAAACTCTTACCAATACACTGAAAGAAGTCAACATGAGATGGAATAACTTGCTGGAAGAGATTGCTGAGCAGCTACA
GTCCAGCAAGGCCCTACTTCAGCTTTGGCAAAGATACAAGGACTACTCCAAACAGTGTGCTTCGACAGTTCAGCAGCAGGAGGATCGAAC
CAATGAGCTGTTGAAGGCAGCCACAAACAAGGACATTGCCGATGATGAGGTTGCCACATGGATTCAAGATTGCAACGACCTCCTCAAAGG
ACTGGGCACAGTTAAAGATTCCCTCTTTTTTCTCCATGAGCTGGGAGAGCAACTGAAGCAACAAGTGGATGCTTCCGCAGCATCAGCTAT
TCAATCGGATCAACTCTCTTTGAGTCAACACTTGTGTGCCCTGGAGCAAGCTCTCTGCAAACAGCAGACTTCATTACAGGCTGGAGTTCT
TGATTATGAAACCTTTGCCAAGAGTTTAGAAGCTTTGGAGGCCTGGATAGTGGAAGCTGAAGAAATACTACAAGGGCAGGACCCTAGCCA
CTCATCTGACCTCTCCACAATCCAGGAAAGGATGGAAGAACTTAAGGGACAGATGTTAAAATTCAGCAGCATGGCTCCAGATTTAGACCG
TCTAAATGAGCTTGGATATAGGTTACCCTTGAATGATAAGGAAATCAAAAGAATGCAGAATCTGAACCGCCATTGGTCTCTGATCTCCTC
TCAGACTACAGAAAGATTCAGCAAGTTGCAGTCATTTTTGCTACAACATCAGACTTTCTTGGAAAAATGTGAAACATGGATGGAATTCCT
AGTTCAGACAGAACAAAAGTTAGCAGTAGAGATTTCAGGAAATTATCAGCACCTTTTGGAACAGCAGAGAGCACACGAGTTGTTTCAAGC
CGAGATGTTCAGTCGTCAGCAGATTTTGCACTCAATCATTATTGATGGGCAACGTCTTCTAGAACAAGGTCAAGTTGATGACAGGGATGA
ATTCAACCTGAAATTGACACTCCTCAGTAATCAATGGCAGGGAGTGATTCGCAGGGCCCAGCAGAGGCGGGGGATCATTGACAGCCAGAT
TCGCCAGTGGCAGCGCTATAGGGAGATGGCAGAAAAGCTTCGTAAATGGTTGGTTGAAGTGTCCTACCTCCCCATGAGTGGTCTCGGAAG
TGTTCCTATACCACTGCAACAAGCAAGGACCCTCTTTGATGAAGTGCAGTTCAAAGAAAAAGTGTTTCTGCGGCAACAAGGCAGCTACAT
CCTGACTGTGGAGGCTGGCAAGCAACTCCTTCTCTCGGCGGACAGTGGCGCTGAGGCCGCCTTGCAGGCCGAACTCGCTGAAATCCAAGA
GAAATGGAAATCAGCCAGCATGCGGCTGGAAGAACAGAAGAAAAAACTAGCCTTCTTGTTGAAAGACTGGGAAAAATGTGAGAAAGGAAT
AGCAGATTCCCTGGAGAAACTACGAACTTTCAAAAAGAAGCTTTCGCAGTCTCTCCCGGATCACCATGAAGAGCTCCATGCAGAACAAAT
GCGTTGCAAGGAATTAGAAAATGCAGTTGGGAGCTGGACAGATGACTTGACCCAGTTGAGCCTGCTGAAGGACACCCTCTCTGCCTATAT
CAGTGCTGATGATATCTCCATTCTTAATGAACGCGTAGAGCTTCTGCAAAGGCAGTGGGAAGAACTATGCCACCAGCTCTCCTTAAGGCG
GCAGCAAATAGGTGAAAGATTGAATGAATGGGCAGTCTTCAGTGAAAAGAACAAGGAACTCTGTGAGTGGTTGACTCAAATGGAAAGCAA
AGTTTCTCAGAATGGAGACATTCTCATTGAAGAAATGATAGAGAAGCTCAAGAAGGATTATCAAGAGGAAATTGCTATTGCTCAAGAGAA
CAAAATACAGCTCCAACAAATGGGAGAACGACTTGCTAAAGCCAGCCATGAAAGCAAAGCATCTGAGATTGAATACAAGCTGGGAAAGGT
CAACGACCGGTGGCAGCATCTCCTGGACCTCATTGCAGCCAGGGTGAAGAAGCTGAAGGAGACCCTGGTAGCCGTGCAGCAGCTTGATAA
GAACATGAGCAGCCTGAGGACCTGGCTCGCTCACATCGAGTCAGAGCTGGCCAAGCCAATAGTCTACGATTCCTGTAACTCGGAAGAAAT
ACAGAGAAAGCTTAATGAGCAGCAGGAGCTTCAGAGAGACATAGAGAAGCACAGTACAGGTGTTGCATCTGTCCTCAACCTGTGTGAAGT
CCTGCTGCACGACTGTGACGCCTGTGCCACTGATGCCGAGTGTGACTCTATACAGCAGGCTACGAGAAACCTGGACCGGCGGTGGAGAAA
CATTTGTGCTATGTCCATGGAAAGGAGGCTGAAAATCGAAGAGACGTGGCGATTGTGGCAGAAATTTCTGGATGACTATTCACGTTTTGA
AGATTGGCTGAAGTCTTCAGAAAGGACAGCTGCTTTTCCCAGCTCTTCTGGGGTGATCTATACAGTTGCCAAGGAAGAACTAAAGAAATT
TGAGGCTTTCCAGCGACAGGTCCACGAGTGCCTGACGCAGCTGGAACTGATCAACAAGCAGTACCGCCGCCTGGCCAGGGAGAACCGCAC
TGATTCAGCATGTAGCCTCAAACAGATGGTTCACGAAGGCAACCAGAGATGGGACAACCTGCAAAAGCGTGTCACCTCCATCTTGCGCAG
ACTCAAGCATTTTATTGGCCAGCGTGAGGAGTTTGAGACTGCGCGGGACAGCATTCTGGTCTGGCTCACAGAGATGGATCTGCAGCTCAC
TAATATTGAACATTTTTCTGAGTGTGATGTTCAAGCTAAAATAAAGCAACTCAAGGCCTTCCAGCAGGAAATTTCACTGAACCACAATAA
GATTGAGCAGATAATTGCCCAAGGAGAACAGCTGATAGAAAAGAGTGAGCCCTTGGATGCAGCGATCATCGAGGAGGAACTAGATGAGCT
CCGACGGTACTGCCAGGAGGTCTTCGGGCGTGTGGAAAGATACCATAAGAAACTGATCCGCCTGCCTCTCCCAGACGATGAGCACGACCT
CTCAGACAGGGAGCTGGAGCTGGAAGACTCTGCAGCTCTGTCGGACCTGCACTGGCACGACCGCTCTGCAGACAGCCTGCTTTCTCCACA
GCCTTCCTCCAATCTCTCCCTCTCGCTCGCTCAGCCCCTCCGGAGCGAGCGGTCAGGACGAGACACCCCGGCTAGTGTGGACTCCATCCC
CCTGGAGTGGGATCACGACTATGACCTCAGTCGGGACCTGGAGTCTGCAATGTCCAGAGCTCTGCCCTCTGAGGATGAAGAAGGTCAGGA
TGACAAAGATTTCTACCTCCGGGGAGCTGTTGGCTTATCAGGGGACCACAGTGCCCTAGAGTCACAGATCCGACAACTGGGCAAAGCCCT
GGATGATAGCCGTTTTCAGATACAGCAAACCGAAAATATCATTCGCAGCAAAACTCCCACGGGGCCGGAGCTAGACACCAGCTACAAAGG
CTACATGAAACTGCTGGGCGAATGCAGTAGCAGTATAGACTCCGTGAAGAGACTGGAGCACAAACTGAAGGAGGAAGAGGAGAGCCTTCC
TGGCTTTGTTAACCTGCATAGTACCGAAACCCAAACGGCTGGTGTGATTGACCGATGGGAGCTTCTCCAGGCCCAGGCATTGAGCAAGGA
GTTGAGGATGAAGCAGAACCTCCAGAAGTGGCAGCAGTTTAACTCAGACTTGAACAGCATCTGGGCCTGGCTGGGGGACACGGAGGAGGA
GTTGGAACAGCTCCAGCGTCTGGAACTCAGCACTGACATCCAGACCATCGAGCTCCAGATCAAAAAGCTCAAGGAGCTCCAGAAAGCTGT
GGACCACCGCAAAGCCATCATCCTCTCCATCAATCTCTGCAGCCCTGAGTTCACCCAGGCTGACAGCAAGGAGAGCCGGGACCTGCAGGA
TCGCTTGTCGCAGATGAATGGGCGCTGGGACCGAGTGTGCTCTCTGCTGGAGGAGTGGCGGGGCCTGCTGCAGGATGCCCTGATGCAGTG
CCAGGGTTTCCATGAAATGAGCCATGGTTTGCTTCTTATGCTGGAGAACATTGACAGAAGGAAAAATGAAATTGTCCCTATTGATTCTAA
CCTTGATGCAGAGATACTTCAGGACCATCACAAACAGCTTATGCAAATAAAGCATGAGCTGTTGGAATCCCAACTCAGAGTAGCCTCTTT
GCAAGACATGTCTTGCCAACTACTGGTGAATGCTGAAGGAACAGACTGTTTAGAAGCCAAAGAAAAAGTCCATGTTATTGGAAATCGGCT
CAAACTTCTCTTGAAGGAGGTCAGTCGTCATATCAAGGAACTGGAGAAGTTATTAGACGTGTCAAGTAGTCAGCAGGATTTGTCTTCCTG
GTCTTCTGCTGATGAACTGGACACCTCAGGGTCTGTGAGTCCCACATCAGGAAGGAGCACCCCAAACAGACAGAAAACGCCACGAGGCAA
GTGTAGTCTCTCACAGCCTGGACCCTCTGTCAGCAGTCCACATAGCAGGTCCACAAAAGGTGGCTCCGATTCCTCCCTTTCTGAGCCAGG
GCCAGGTCGGTCCGGCCGCGGCTTCCTGTTCAGAGTCCTCCGAGCAGCTCTTCCCCTTCAGCTTCTCCTGCTCCTCCTCATCGGGCTTGC
CTGCCTTGTACCAATGTCAGAGGAAGACTACAGCTGTGCCCTCTCCAACAACTTTGCCCGGTCATTCCACCCCATGCTCAGATACACGAA
TGGCCCTCCTCCACTCTGAACTAAGCAGATGCCATCTGCAGAAGTGCTGGTAGCATAAGGAGGATCGGGTCATAAGCAATCCCAAACTAC
CAACAAGAGGACCTTGATCTTGGCGAAAGCCCTCGGTGTGGCAGCTTTAGCCCTCCTCCAGATCACATGTGTGCAAATTATGGCTTCAGA
GGTGGAAGATAAACAGTGACGGGGGAACAAACAGACAACAAGAAGGTTTGGAAGAAATCTGGTTTGAGACTCTGAACCTTAGCACTAAGG
AGATTGAGTAAGGACCTCCAAAGTTCCCCGGACTCATGAATTCTGGGCCCTTGGCCCATTCTGTGCACAGCCAAGGACTTCAGTAGACCA
TCTGGGCAGCTTTCCCATGGTGCTGCTCCAACCATCAGATAAATGACCCTCCCAAGCACCATGTCAGTGTCGTACAATCTACCAACCAAC
CAGTGCTGAAGAGATTTTAGAACCTTGTAACATACAATTTTTAAGAGCTTATATGGCAGCTTCCTTTTTACCTTGTTTTCCTTTGGGGCA
TGATGTTTTAACCTTTGCTTTAGAAGCACAAGCTGTAAATCTAAAAGGCACTTTTTTTTAGAGGTATAAAGAAAAACTAGATGTAATAAA
TAAGATCATGGAAGGCTTTATGTGAAAAAAGTTGAATGTTATAGTAAAAAAAAAAAGATATTTATGTATGTACAGTTTGCTAAAGCCAAG

>In-frame_ENST00000377242_ENST00000367255_TCGA-A8-A07R-01A_PLXDC2_chr10_20290915_+_SYNE1_chr6_152793548_length(amino acids)=8455AA_start in transcript=841_stop in transcript=26208
MARFPKADLAAAGVMLLCHFFTDQFQFADGKPGDQILDWQYGVTQAFPHTEEEVEVDSHAYSHRWKRNLDFLKAVDTNRASVGQDSPEPR
SFTDLLLDDGQDNNTQIEDLLQNTDAHKRAFHEIYRTRSVNGIPVPPDQLEDMAERFHFVSSTSELHLMKMEFLELKYRLLSLLVLAESK
LKSWIIKYGRRESVEQLLQNYVSFIENSKFFEQYEVTYQILKQTAEMYVKADGSVEEAENVMKFMNETTAQWRNLSVEVRSVRSMLEEVI
SNWDRYGNTVASLQAWLEDAEKMLNQSENAKKDFFRNLPHWIQQHTAMNDAGNFLIETCDEMVSRDLKQQLLLLNGRWRELFMEVKQYAQ
ADEMDRMKKEYTDCVVTLSAFATEAHKKLSEPLEVSFMNVKLLIQDLEDIEQRVPVMDAQYKIITKTAHLITKESPQEEGKEMFATMSKL
KEQLTKVKECYSPLLYESQQLLIPLEELEKQMTSFYDSLGKINEIITVLEREAQSSALFKQKHQELLACQENCKKTLTLIEKGSQSVQKF
VTLSNVLKHFDQTRLQRQIADIHVAFQSMVKKTGDWKKHVETNSRLMKKFEESRAELEKVLRIAQEGLEEKGDPEELLRRHTEFFSQLDQ
RVLNAFLKACDELTDILPEQEQQGLQEAVRKLHKQWKDLQGEAPYHLLHLKIDVEKNRFLASVEECRTELDRETKLMPQEGSEKIIKEHR
VFFSDKGPHHLCEKRLQLIEELCVKLPVRDPVRDTPGTCHVTLKELRAAIDSTYRKLMEDPDKWKDYTSRFSEFSSWISTNETQLKGIKG
EAIDTANHGEVKRAVEEIRNGVTKRGETLSWLKSRLKVLTEVSSENEAQKQGDELAKLSSSFKALVTLLSEVEKMLSNFGDCVQYKEIVK
NSLEELISGSKEVQEQAEKILDTENLFEAQQLLLHHQQKTKRISAKKRDVQQQIAQAQQGEGGLPDRGHEELRKLESTLDGLERSRERQE
RRIQVTLRKWERFETNKETVVRYLFQTGSSHERFLSFSSLESLSSELEQTKEFSKRTESIAVQAENLVKEASEIPLGPQNKQLLQQQAKS
IKEQVKKLEDTLEEDIKTMEMVKTKWDHFGSNFETLSVWITEKEKELNALETSSSAMDMQISQIKVTIQEIESKLSSIVGLEEEAQSFAQ
FVTTGESARIKAKLTQIRRYGEELREHAQCLEGTILGHLSQQQKFEENLRKIQQSVSEFEDKLAVPIKICSSATETYKVLQEHMDLCQAL
ESLSSAITAFSASARKVVNRDSCVQEAAALQQQYEDILRRAKERQTALENLLAHWQRLEKELSSFLTWLERGEAKASSPEMDISADRVKV
EGELQLIQALQNEVVSQASFYSKLLQLKESLFSVASKDDVKMMKLHLEQLDERWRDLPQIINKRINFLQSVVAEHQQFDELLLSFSVWIK
LFLSELQTTSEISIMDHQVALTRHKDHAAEVESKKGELQSLQGHLAKLGSLGRAEDLHLLQGKAEDCFQLFEEASQVVERRQLALSHLAE
FLQSHASLSGILRQLRQTVEATNSMNKNESDLIEKDLNDALQNAKALESAAVSLDGILSKAQYHLKIGSSEQRTSCRATADQLCGEVERI
QNLLGTKQSEADALAVLKKAFQDQKEELLKSIEDIEERTDKERLKEPTRQALQQRLRVFNQLEDELNSHEHELCWLKDKAKQIAQKDVAF
APEVDREINRLEVTWDDTKRLIHENQGQCCGLIDLMREYQNLKSAVSKVLENASSVIVTRTTIKDQEDLKWAFSKHETAKNKMNYKQKDL
DNFTSKGKHLLSELKKIHSSDFSLVKTDMESTVDKWLDVSEKLEENMDRLRVSLSIWDDVLSTRDEIEGWSNNCVPQMAENISNLDNHLR
AEELLKEFESEVKNKALRLEELHSKVNDLKELTKNLETPPDLQFIEADLMQKLEHAKEITEVAKGTLKDFTAQSTQVEKFINDITTWFTK
VEESLMNCAQNETCEALKKVKDIQKELQSQQSNISSTQENLNSLCRKYHSAELESLGRAMTGLIKKHEAVSQLCSKTQASLQESLEKHFS
ESMQEFQEWFLGAKAAAKESSDRTGDSKVLEAKLHDLQNILDSVSDGQSKLDAVTQEGQTLYAHLSKQIVSSIQEQITKANEEFQAFLKQ
CLKDKQALQDCASELGSFEDQHRKLNLWIHEMEERFNTENLGESKQHIPEKKNEVHKVEMFLGELLAARESLDKLSQRGQLLSEEGHGAG
QEGRLCSQLLTSHQNLLRMTKEKLRSCQVALQEHEALEEALQSMWFWVKAIQDRLACAESTLGSKDTLEKRLSQIQDILLMKGEGEVKLN
MAIGKGEQALRSSNKEGQRVIQTQLETLKEVWADIMSSSVHAQSTLESVISQWNDYVERKNQLEQWMESVDQKIEHPLQPQPGLKEKFVL
LDHLQSILSEAEDHTRALHRLIAKSRELYEKTEDESFKDTAQEELKTQFNDIMTVAKEKMRKVEEIVKDHLMYLDAVHEFTDWLHSAKEE
LHRWSDMSGDSSATQKKLSKIKELIDSREIGASRLSRVESLAPEVKQNTTASGCELMHTEMQALRADWKQWEDSVFQTQSCLENLVSQMA
LSEQEFSGQVAQLEQALEQFSALLKTWAQQLTLLEGKNTDEEIVECWHKGQEILDALQKAEPRTEDLKSQLNELCRFSRDLSTYSGKVSG
LIKEYNCLCLQASKGCQNKEQILQQRFRKAFRDFQQWLVNAKITTAKCFDIPQNISEVSTSLQKIQEFLSESENGQHKLNMMLSKGELLS
TLLTKEKAKGIQAKVTAAKEDWKNFHSNLHQKESALENLKIQMKDFEVSAEPIQDWLSKTEKMVHESSNRLYDLPAKRREQQKLQSVLEE
IHCYEPQLNRLKEKAQQLWEGQAASKSFRHRVSQLSSQYLALSNLTKEKVSRLDRIVAEHNQFSLGIKELQDWMTDAIHMLDSYCHPTSD
KSVLDSRTLKLEALLSVKQEKEIQMKMIVTRGESVLQNTSPEGIPTIQQQLQSVKDMWASLLSAGIRCKSQLEGALSKWTSYQDGVRQFS
GWMDSMEANLNESERQHAELRDKTTMLGKAKLLNEEVLSYSSLLETIEVKGAGMTEHYVTQLELQDLQERYRAIQERAKEAVTKSEKLVR
LHQEYQRDLKAFEVWLGQEQEKLDQYSVLEGDAHTHETTLRDLQELQVHCAEGQALLNSVLHTREDVIPSGIPQAEDRALESLRQDWQAY
QHRLSETRTQFNNVVNKLRLMEQKFQQVDEWLKTAEEKVSPRTRRQSNRATKEIQLHQMKKWHEEVTAYRDEVEEVGARAQEILDESHVN
SRMGCQATQLTSRYQALLLQVLEQIKFLEEEIQSLEESESSLSSYSDWYGSTHKNFKNVATKIDKVDTVMMGKKLKTLEVLLKDMEKGHS
LLKSAREKGERAVKYLEEGEAERLRKEIHDHMEQLKELTSTVRKEHMTLEKGLHLAKEFSDKCKALTQWIAEYQEILHVPEEPKMELYEK
KAQLSKYKSLQQTVLSHEPSVKSVREKGEALLELVQDVTLKDKIDQLQSDYQDLCSIGKEHVFSLEAKVKDHEDYNSELQEVEKWLLQMS
GRLVAPDLLETSSLETITQQLAHHKAMMEEIAGFEDRLNNLQMKGDTLIGQCADHLQAKLKQNVHAHLQGTKDSYSAICSTAQRMYQSLE
HELQKHVSRQDTLQQCQAWLSAVQPDLEPSPQPPLSRAEAIKQVKHFRALQEQARTYLDLLCSMCDLSNASVKTTAKDIQQTEQTIEQKL
VQAQNLTQGWEEIKHLKSELWIYLQDADQQLQNMKRRHSELELNIAQNMVSQVKDFVKKLQSKQASVNTIIEKVNKLTKKEESPEHKEIN
HLNDQWLDLCRQSNNLCLQREEDLQRTRDYHDCMNVVEVFLEKFTTEWDNLARSDAESTAVHLEALKKLALALQERKYAIEDLKDQKQKM
IEHLNLDDKELVKEQTSHLEQRWFQLEDLIKRKIQVSVTNLEELNVVQSRFQELMEWAEEQQPNIAEALKQSPPPDMAQNLLMDHLAICS
ELEAKQMLLKSLIKDADRVMADLGLNERQVIQKALSDAQSHVNCLSDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREHI
CLLPDDVSKQVKTCKSAQASLKTYQNEVTGLWAQGRELMKEVTEQEKSEVLGKLQELQSVYDSVLQKCSHRLQELEKNLVSRKHFKEDFD
KACHWLKQADIVTFPEINLMNESSELHTQLAKYQNILEQSPEYENLLLTLQRTGQTILPSLNEVDHSYLSEKLNALPRQFNVIVALAKDK
FYKVQEAILARKEYASLIELTTQSLSELEAQFLRMSKVPTDLAVEEALSLQDGCRAILDEVAGLGEAVDELNQKKEGFRSTGQPWQPDKM
LHLVTLYHRLKRQTEQRVSLLEDTTSAYQEHEKMCQQLERQLKSVKEEQSKVNEETLPAEEKLKMYHSLAGSLQDSGIVLKRVTIHLEDL
APHLDPLAYEKARHQIQSWQGELKLLTSAIGETVTECESRMVQSIDFQTEMSRSLDWLRRVKAELSGPVYLDLNLQDIQEEIRKIQIHQE
EVQSSLRIMNALSHKEKEKFTKAKELISADLEHSLAELSELDGDIQEALRTRQATLTEIYSQCQRYYQVFQAANDWLEDAQELLQLAGNG
LDVESAEENLKSHMEFFSTEDQFHSNLEELHSLVATLDPLIKPTGKEDLEQKVASLELRSQRMSRDSGAQVDLLQRCTAQWHDYQKAREE
VIELMNDTEKKLSEFSLLKTSSSHEAEEKLSEHKALVSVVNSFHEKIVALEEKASQLEKTGNDASKATLSRSMTTVWQRWTRLRAVAQDQ
EKILEDAVDEWTGFNNKVKKATEMIDQLQDKLPGSSAEKASKAELLTLLEYHDTFVLELEQQQSALGMLRQQTLSMLQDGAAPTPGEEPP
LMQEITAMQDRCLNMQEKVKTNGKLVKQELKDREMVETQINSVKCWVQETKEYLGNPTIEIDAQLEELQILLTEATNHRQNIEKMAEEQK
EKYLGLYTILPSELSLQLAEVALDLKIRDQIQDKIKEVEQSKATSQELSRQIQKLAKDLTTILTKLKAKTDNVVQAKTDQKVLGEELDGC
NSKLMELDAAVQKFLEQNGQLGKPLAKKIGKLTELHQQTIRQAENRLSKLNQAASHLEEYNEMLELILKWIEKAKVLAHGTIAWNSASQL
REQYILHQTLLEESKEIDSELEAMTEKLQYLTSVYCTEKMSQQVAELGRETEELRQMIKIRLQNLQDAAKDMKKFEAELKKLQAALEQAQ
ATLTSPEVGRLSLKEQLSHRQHLLSEMESLKPKVQAVQLCQSALRIPEDVVASLPLCHAALRLQEEASRLQHTAIQQCNIMQEAVVQYEQ
YEQEMKHLQQLIEGAHREIEDKPVATSNIQELQAQISRHEELAQKIKGYQEQIASLNSKCKMLTMKAKHATMLLTVTEVEGLAEGTEDLD
GELLPTPSAHPSVVMMTAGRCHTLLSPVTEESGEEGTNSEISSPPACRSPSPVANTDASVNQDIAYYQALSAERLQTDAAKIHPSTSASQ
EFYEPGLEPSATAKLGDLQRSWETLKNVISEKQRTLYEALERQQKYQDSLQSISTKMEAIELKLSESPEPGRSPESQMAEHQALMDEILM
LQDEINELQSSLAEELVSESCEADPAEQLALQSTLTVLAERMSTIRMKASGKRQLLEEKLNDQLEEQRQEQALQRYRCEADELDSWLLST
KATLDTALSPPKEPMDMEAQLMDCQNMLVEIEQKVVALSELSVHNENLLLEGKAHTKDEAEQLAGKLRRLKGSLLELQRALHDKQLNMQG
TAQEKEESDVDLTATQSPGVQEWLAQARTTWTQQRQSSLQQQKELEQELAEQKSLLRSVASRGEEILIQHSAAETSGDAGEKPDVLSQEL
GMEGEKSSAEDQMRMKWESLHQEFSTKQKLLQNVLEQEQEQVLYSRPNRLLSGVPLYKGDVPTQDKSAVTSLLDGLNQAFEEVSSQSGGA
KRQSIHLEQKLYDGVSATSTWLDDVEERLFVATALLPEETETCLFNQEILAKDIKEMSEEMDKNKNLFSQAFPENGDNRDVIEDTLGCLL
GRLSLLDSVVNQRCHQMKERLQQILNFQNDLKVLFTSLADNKYIILQKLANVFEQPVAEQIEAIQQAEDGLKEFDAGIIELKRRGDKLQV
EQPSMQELSKLQDMYDELMMIIGSRRSGLNQNLTLKSQYERALQDLADLLETGQEKMAGDQKIIVSSKEEIQQLLDKHKEYFQGLESHMI
LTETLFRKIISFAVQKETQFHTELMAQASAVLKRAHKRGVELEYILETWSHLDEDQQELSRQLEVVESSIPSVGLVEENEDRLIDRITLY
QHLKSSLNEYQPKLYQVLDDGKRLLISISCSDLESQLNQLGECWLSNTNKMSKELHRLETILKHWTRYQSESADLIHWLQSAKDRLEFWT
QQSVTVPQELEMVRDHLNAFLEFSKEVDAQSSLKSSVLSTGNQLLRLKKVDTATLRSELSRIDSQWTDLLTNIPAVQEKLHQLQMDKLPS
RHAISEVMSWISLMENVIQKDEDNIKNSIGYKAIHEYLQKYKGFKIDINCKQLTVDFVNQSVLQISSQDVESKRSDKTDFAEQLGAMNKS
WQILQGLVTEKIQLLEGLLESWSEYENNVQCLKTWFETQEKRLKQQHRIGDQASVQNALKDCQDLEDLIKAKEKEVEKIEQNGLALIQNK
KEDVSSIVMSTLRELGQTWANLDHMVGQLKILLKSVLDQWSSHKVAFDKINSYLMEARYSLSRFRLLTGSLEAVQVQVDNLQNLQDDLEK
QERSLQKFGSITNQLLKECHPPVTETLTNTLKEVNMRWNNLLEEIAEQLQSSKALLQLWQRYKDYSKQCASTVQQQEDRTNELLKAATNK
DIADDEVATWIQDCNDLLKGLGTVKDSLFFLHELGEQLKQQVDASAASAIQSDQLSLSQHLCALEQALCKQQTSLQAGVLDYETFAKSLE
ALEAWIVEAEEILQGQDPSHSSDLSTIQERMEELKGQMLKFSSMAPDLDRLNELGYRLPLNDKEIKRMQNLNRHWSLISSQTTERFSKLQ
SFLLQHQTFLEKCETWMEFLVQTEQKLAVEISGNYQHLLEQQRAHELFQAEMFSRQQILHSIIIDGQRLLEQGQVDDRDEFNLKLTLLSN
QWQGVIRRAQQRRGIIDSQIRQWQRYREMAEKLRKWLVEVSYLPMSGLGSVPIPLQQARTLFDEVQFKEKVFLRQQGSYILTVEAGKQLL
LSADSGAEAALQAELAEIQEKWKSASMRLEEQKKKLAFLLKDWEKCEKGIADSLEKLRTFKKKLSQSLPDHHEELHAEQMRCKELENAVG
SWTDDLTQLSLLKDTLSAYISADDISILNERVELLQRQWEELCHQLSLRRQQIGERLNEWAVFSEKNKELCEWLTQMESKVSQNGDILIE
EMIEKLKKDYQEEIAIAQENKIQLQQMGERLAKASHESKASEIEYKLGKVNDRWQHLLDLIAARVKKLKETLVAVQQLDKNMSSLRTWLA
HIESELAKPIVYDSCNSEEIQRKLNEQQELQRDIEKHSTGVASVLNLCEVLLHDCDACATDAECDSIQQATRNLDRRWRNICAMSMERRL
KIEETWRLWQKFLDDYSRFEDWLKSSERTAAFPSSSGVIYTVAKEELKKFEAFQRQVHECLTQLELINKQYRRLARENRTDSACSLKQMV
HEGNQRWDNLQKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIEHFSECDVQAKIKQLKAFQQEISLNHNKIEQIIAQGEQ
LIEKSEPLDAAIIEEELDELRRYCQEVFGRVERYHKKLIRLPLPDDEHDLSDRELELEDSAALSDLHWHDRSADSLLSPQPSSNLSLSLA
QPLRSERSGRDTPASVDSIPLEWDHDYDLSRDLESAMSRALPSEDEEGQDDKDFYLRGAVGLSGDHSALESQIRQLGKALDDSRFQIQQT
ENIIRSKTPTGPELDTSYKGYMKLLGECSSSIDSVKRLEHKLKEEEESLPGFVNLHSTETQTAGVIDRWELLQAQALSKELRMKQNLQKW
QQFNSDLNSIWAWLGDTEEELEQLQRLELSTDIQTIELQIKKLKELQKAVDHRKAIILSINLCSPEFTQADSKESRDLQDRLSQMNGRWD
RVCSLLEEWRGLLQDALMQCQGFHEMSHGLLLMLENIDRRKNEIVPIDSNLDAEILQDHHKQLMQIKHELLESQLRVASLQDMSCQLLVN
AEGTDCLEAKEKVHVIGNRLKLLLKEVSRHIKELEKLLDVSSSQQDLSSWSSADELDTSGSVSPTSGRSTPNRQKTPRGKCSLSQPGPSV

--------------------------------------------------------------
>In-frame_ENST00000377252_ENST00000367255_TCGA-A8-A07R-01A_PLXDC2_chr10_20290915_+_SYNE1_chr6_152793548_length(transcript)=26961nt_BP=1165nt
GGCGACGGCAGCGCCTCCTCCGCCACCAAACTCCTGGGGCTCCGCGGGGGCTTGGGGCCACCTCCTCCTGAGCCCGGAGGAACCCTCTCC
CGATAGGTTCCAGCGTGACTCCCTCCCACTCCACCCTTTTCCTTTCTTCTTCCTCTTTTTTTTTTTTTTTTTTAAACACATTTTTTTCCT
GGCTTCGGACCTCAGACTGCTGCAGCCCTAACCTTCCCAGGGCTCAGCTCTTTGGAGCTGCCCATTCCTCCGGCTGCGAGAAAGGACGCG
CGCCCTGCGTCGGGCGAAGAAAAGAAGCAAAACTTGTCGGGAGGGTTTCGTCATCAACCTCCTTCCCGCAAACCTAAACCTCCTGCCGGG
GCCATCCCTAGACAGAGGAAAGTTCCTGCAGAGCCGACCAGCCCTAGTGGATCTGGGGCAGGCAGCGGCGCTGGCTGTGGAATTAGATCT
GTTTTGAACCCAGTGGAGCGCATCGCTGGGGCTCGGAAGTCACCGTCCGCGGGCACCGGGTTGGCGCTGCCCGAGTGGAACCGACAGTTT
GCGAGCCTCGGCTGCAAGTGGCCTCTCCTCCCCGCGGTTGTTGTTCAGTGTCGGGTGAGGGCTGCGAGTGTGGCAAGTTGCAAAGAGAGC
CTCAGAGGTCCGAAGAGCGCTGCGCTCCTACTCGCGTTCGCTTCTTCCTCTTCTCGGTTCCCTACTGTGAAATCGCAGCGACATTTACAA
AGGCCTCCGGGTCCTACCGAGACCGATCCGCAGCGTTTGGCCCGGTCGTGCCTATTGCATCGGGAGCCCCCGAGCACCGGCGAAGGACTG
GCGGGTGGGGTAGGGAGGTGGCGGCGGCGGCATGGCGAGGTTCCCGAAGGCCGACCTGGCCGCTGCAGGAGTTATGTTACTTTGCCACTT
CTTCACGGACCAGTTTCAGTTCGCCGATGGGAAACCCGGAGACCAAATCCTTGATTGGCAGTATGGAGTTACTCAGGCCTTCCCTCACAC
AGAGGAGGAGGTGGAAGTTGATTCACACGCGTACAGCCACAGGTGGAAAAGAAACTTGGACTTTCTCAAGGCGGTAGACACGAACCGAGC
AAGCGTCGGCCAAGACTCTCCTGAGCCCAGAAGCTTCACAGACCTGCTGCTGGATGATGGGCAGGACAATAACACTCAGATCGAGGATCT
GCTTCAAAACACGGATGCCCACAAAAGAGCATTCCATGAAATCTACCGGACCAGGTCTGTTAACGGGATTCCAGTGCCACCTGATCAATT
AGAGGACATGGCCGAGAGGTTTCATTTTGTTTCCTCCACATCAGAGCTACACCTAATGAAAATGGAATTTTTAGAATTAAAGTACCGTCT
GCTCTCACTGCTGGTTCTTGCAGAGTCAAAGCTGAAGTCTTGGATCATTAAGTACGGGAGGAGAGAGTCAGTGGAGCAGCTTCTACAAAA
CTACGTGTCTTTTATAGAAAATAGCAAGTTCTTTGAACAATATGAGGTGACATACCAGATCTTGAAACAGACAGCTGAGATGTATGTCAA
AGCAGATGGTTCAGTGGAAGAAGCTGAGAATGTGATGAAATTCATGAATGAAACCACCGCTCAGTGGAGGAATCTCTCAGTAGAAGTGAG
GAGTGTGAGGAGCATGCTGGAAGAAGTGATCTCTAACTGGGATCGCTATGGCAATACAGTGGCTAGTCTGCAAGCCTGGCTAGAGGATGC
TGAAAAAATGCTCAATCAATCAGAAAATGCCAAAAAGGATTTTTTTCGAAATTTACCTCATTGGATTCAGCAGCATACTGCCATGAACGA
TGCTGGCAATTTTCTAATTGAAACCTGTGATGAGATGGTTTCCCGTGACCTGAAGCAGCAATTACTGTTGCTAAATGGGCGGTGGAGGGA
GTTGTTTATGGAAGTCAAGCAATATGCTCAAGCTGATGAGATGGACAGAATGAAGAAGGAATACACAGACTGTGTTGTTACCCTGTCTGC
TTTTGCAACGGAAGCCCATAAGAAACTTTCTGAACCCTTAGAAGTCTCTTTTATGAATGTCAAGCTATTAATTCAAGACTTGGAGGATAT
TGAGCAGAGGGTGCCTGTGATGGATGCCCAATACAAGATAATTACAAAGACAGCACACCTCATTACCAAAGAAAGCCCCCAAGAAGAAGG
AAAAGAAATGTTTGCGACCATGTCAAAGCTCAAAGAGCAGCTAACCAAGGTCAAAGAATGTTACTCCCCACTCCTTTATGAGTCTCAGCA
GCTGTTGATTCCGTTGGAGGAATTAGAAAAGCAGATGACGTCCTTTTATGACTCACTTGGGAAAATCAATGAAATTATCACAGTTCTTGA
GCGTGAGGCACAATCGAGTGCCCTTTTTAAACAAAAACATCAGGAACTGTTAGCTTGTCAAGAAAACTGTAAGAAAACCTTGACACTTAT
TGAGAAAGGCAGTCAAAGTGTTCAAAAGTTTGTGACCTTGAGCAACGTGTTAAAGCATTTTGATCAGACGAGGCTACAAAGACAGATTGC
AGATATTCATGTTGCTTTTCAGAGTATGGTAAAGAAAACTGGAGATTGGAAGAAGCATGTGGAAACCAACAGTCGCTTGATGAAGAAGTT
TGAGGAGTCTCGAGCAGAGTTGGAGAAGGTACTGCGGATTGCTCAGGAGGGCCTGGAGGAAAAGGGGGATCCAGAGGAGCTCCTGCGGAG
ACACACTGAGTTTTTCAGTCAGCTGGATCAGAGGGTGCTCAATGCTTTCCTGAAAGCTTGTGATGAACTCACCGACATCCTTCCAGAGCA
GGAGCAGCAGGGGCTGCAGGAAGCTGTTCGAAAGCTCCACAAACAATGGAAGGATCTTCAAGGAGAAGCCCCTTATCATTTGCTTCATCT
GAAGATTGATGTGGAGAAGAATAGGTTCTTAGCCTCTGTAGAAGAATGCAGAACTGAGCTGGATCGAGAGACCAAGCTGATGCCCCAGGA
AGGCAGTGAAAAGATAATTAAAGAGCACAGGGTTTTCTTCAGTGACAAAGGTCCTCATCATCTCTGTGAGAAAAGGTTACAGCTCATCGA
GGAACTCTGTGTGAAACTCCCAGTGCGGGACCCAGTAAGGGACACACCTGGAACCTGTCACGTGACTCTCAAAGAGCTCAGAGCTGCCAT
TGACAGCACCTACAGGAAGCTCATGGAAGACCCAGACAAGTGGAAGGACTACACTAGCAGATTCTCTGAGTTCTCATCTTGGATATCTAC
AAATGAGACACAATTAAAGGGGATCAAGGGTGAGGCCATCGATACTGCCAACCACGGAGAGGTTAAACGTGCCGTTGAAGAGATCAGAAA
TGGTGTTACCAAAAGGGGTGAGACCCTCAGCTGGCTGAAATCCAGGCTGAAAGTTTTGACAGAAGTTTCTTCTGAGAATGAAGCCCAAAA
GCAGGGAGATGAGCTGGCAAAATTATCCAGCTCTTTCAAGGCTCTTGTGACGCTGCTGTCAGAGGTTGAAAAGATGCTAAGCAATTTTGG
GGACTGTGTCCAGTACAAAGAAATAGTCAAAAATTCTCTCGAAGAATTAATTTCTGGCTCTAAAGAAGTCCAGGAACAAGCTGAGAAGAT
CTTGGATACTGAAAATCTGTTTGAAGCACAGCAGTTACTTCTTCATCACCAGCAAAAGACAAAGCGGATCTCAGCAAAGAAGAGAGATGT
GCAGCAGCAGATCGCGCAGGCGCAGCAGGGAGAAGGGGGGCTGCCTGACCGAGGCCACGAGGAGCTGCGGAAGCTGGAGAGCACACTGGA
TGGCCTGGAGCGCAGCCGGGAGAGGCAGGAACGCCGCATCCAGGTCACATTAAGAAAATGGGAGCGATTTGAAACAAACAAAGAAACAGT
AGTAAGATACCTTTTTCAAACAGGTTCCAGTCATGAACGCTTCTTGAGTTTTAGCAGTTTGGAAAGTTTATCTTCAGAACTGGAACAAAC
AAAGGAGTTTTCTAAACGGACAGAAAGTATTGCAGTCCAGGCTGAGAACCTTGTAAAGGAAGCTTCAGAGATACCGCTTGGGCCCCAAAA
TAAGCAGCTGCTTCAACAGCAGGCCAAGTCAATCAAAGAACAAGTCAAAAAATTAGAAGACACGCTTGAAGAAGATATTAAAACCATGGA
AATGGTGAAAACCAAGTGGGATCATTTTGGCAGTAATTTTGAGACTCTGTCCGTCTGGATAACTGAGAAAGAAAAAGAACTCAATGCCTT
GGAAACTTCGTCATCTGCCATGGACATGCAAATCAGCCAAATTAAGGTCACAATTCAGGAAATAGAAAGTAAGCTCAGCAGCATTGTAGG
ATTAGAAGAAGAAGCCCAGTCTTTTGCTCAGTTTGTTACCACTGGAGAATCTGCTCGAATTAAAGCCAAGTTGACACAAATAAGAAGATA
CGGGGAAGAGCTTCGAGAGCATGCACAGTGTCTGGAAGGAACAATCCTGGGACATTTATCTCAGCAGCAAAAGTTTGAAGAGAACCTTAG
AAAGATCCAGCAATCTGTGTCTGAATTTGAAGATAAACTTGCTGTTCCAATTAAAATATGTTCTTCAGCTACAGAAACATACAAAGTTCT
TCAAGAACATATGGATCTCTGCCAGGCCCTGGAGTCACTGAGCAGCGCGATCACTGCCTTCTCAGCCAGTGCCAGGAAGGTTGTGAACAG
AGATTCCTGTGTTCAGGAGGCTGCGGCTCTACAGCAGCAATACGAGGACATCCTAAGGAGGGCGAAGGAGAGACAGACGGCGCTGGAGAA
TCTGCTGGCCCACTGGCAGAGGCTAGAGAAAGAACTATCATCCTTTTTGACCTGGTTAGAGCGGGGTGAAGCTAAAGCCAGTTCCCCAGA
AATGGACATTTCTGCAGACAGAGTCAAAGTGGAAGGTGAACTTCAGTTAATACAGGCACTGCAAAATGAAGTTGTATCCCAGGCCTCATT
CTATAGCAAACTTTTGCAATTGAAGGAATCATTGTTCTCAGTAGCCTCCAAAGATGATGTGAAAATGATGAAACTACATTTGGAGCAGTT
GGATGAGAGATGGAGAGATTTACCACAGATCATTAACAAAAGGATTAATTTTCTTCAGTCTGTGGTTGCTGAACACCAGCAATTTGATGA
GCTGCTGCTTTCCTTTTCTGTCTGGATTAAACTGTTTCTCAGTGAATTACAAACTACCTCTGAGATTAGCATAATGGACCATCAAGTAGC
CCTTACTCGGCATAAGGACCACGCAGCAGAAGTAGAGAGCAAAAAGGGCGAATTGCAGAGTCTGCAGGGTCACTTAGCAAAGTTGGGTTC
TCTGGGCCGTGCTGAGGACCTCCACCTCCTGCAGGGAAAGGCTGAGGACTGCTTCCAGCTGTTTGAGGAGGCCAGCCAGGTTGTGGAGAG
GCGGCAGCTTGCCCTGTCCCATTTGGCAGAATTCCTCCAGAGCCATGCCTCTCTGTCCGGCATTCTCCGCCAGCTGAGGCAAACAGTGGA
AGCAACCAACAGTATGAATAAGAACGAGTCTGATTTGATAGAAAAGGACCTCAATGATGCTCTTCAAAATGCTAAAGCATTAGAATCTGC
TGCCGTCAGTCTGGATGGCATTCTTTCCAAAGCCCAATACCATCTGAAAATCGGGAGCTCTGAGCAAAGGACTTCCTGCAGAGCCACGGC
TGATCAGCTCTGTGGAGAGGTAGAGAGGATCCAGAACCTTCTGGGAACCAAGCAGAGTGAGGCAGATGCTCTGGCAGTGTTGAAAAAAGC
ATTCCAAGACCAGAAAGAGGAGCTTCTGAAAAGCATTGAGGACATTGAAGAAAGGACTGACAAAGAGCGATTGAAAGAACCTACCCGCCA
AGCTCTTCAGCAGAGGTTAAGAGTGTTTAATCAGCTAGAAGATGAATTGAATTCTCACGAGCATGAACTATGTTGGTTGAAAGACAAAGC
CAAGCAAATTGCCCAGAAAGATGTAGCTTTTGCACCTGAAGTTGACAGGGAGATAAACCGCTTAGAGGTCACCTGGGATGATACCAAAAG
ACTAATTCATGAAAATCAGGGTCAGTGCTGTGGACTTATTGACTTAATGAGAGAATATCAGAACCTGAAATCAGCTGTATCTAAAGTCTT
AGAAAATGCCAGCAGTGTGATTGTAACCAGAACTACCATAAAAGATCAGGAGGATCTTAAATGGGCTTTTTCCAAGCATGAAACTGCCAA
GAACAAAATGAATTACAAACAGAAAGACTTGGATAACTTTACCAGCAAAGGAAAACACTTGTTATCTGAGCTGAAGAAAATTCACAGTAG
TGATTTCAGCTTGGTGAAAACAGACATGGAGAGCACCGTGGACAAATGGCTGGATGTATCAGAGAAACTTGAAGAAAACATGGATAGGCT
GAGAGTAAGCCTGTCCATTTGGGATGATGTACTGTCAACTAGAGATGAGATTGAGGGATGGTCAAACAACTGCGTTCCACAGATGGCAGA
AAACATCAGCAACCTGGATAACCACCTCAGAGCTGAAGAACTGCTTAAAGAATTTGAGTCTGAAGTTAAAAACAAAGCATTGAGATTGGA
AGAACTGCATTCCAAAGTTAATGATCTGAAAGAATTAACTAAAAATCTAGAAACACCGCCAGACCTTCAGTTTATAGAAGCAGACTTAAT
GCAGAAACTGGAGCATGCCAAAGAAATAACTGAAGTAGCAAAAGGAACCCTGAAGGATTTCACGGCTCAAAGTACACAAGTGGAGAAGTT
TATTAATGACATAACAACATGGTTCACAAAAGTGGAAGAATCGTTGATGAACTGTGCCCAAAATGAGACTTGTGAAGCATTGAAAAAAGT
CAAGGATATACAAAAAGAACTTCAAAGTCAACAAAGCAACATCAGCTCTACCCAAGAAAATCTCAATAGCTTGTGCCGCAAGTACCACTC
AGCTGAGTTGGAGAGCCTGGGCCGTGCAATGACTGGTCTGATAAAGAAACATGAAGCCGTGAGCCAGTTGTGCTCCAAAACCCAGGCCAG
CCTGCAGGAATCTCTGGAAAAACACTTCAGTGAGTCTATGCAGGAATTCCAAGAATGGTTTTTGGGAGCAAAGGCAGCAGCAAAAGAATC
ATCAGATCGCACCGGTGACAGCAAAGTTCTAGAAGCAAAGCTCCATGATCTTCAGAACATTTTGGACTCAGTCAGTGATGGGCAGAGCAA
ACTTGATGCAGTGACTCAAGAAGGACAAACTTTGTATGCACATTTGTCTAAACAAATTGTCAGTAGCATTCAAGAACAAATCACAAAGGC
CAATGAAGAGTTTCAAGCATTTCTGAAACAATGCCTTAAAGATAAGCAGGCTCTTCAAGACTGTGCTTCAGAACTTGGAAGCTTTGAAGA
TCAGCACAGAAAACTGAACTTATGGATCCATGAAATGGAAGAAAGGTTCAATACGGAAAACTTGGGAGAGAGTAAACAGCACATTCCTGA
GAAGAAAAATGAAGTTCATAAAGTTGAAATGTTTTTGGGAGAACTGCTGGCTGCAAGAGAGTCTCTTGATAAGCTTTCCCAGAGAGGGCA
GCTTCTGAGTGAAGAAGGCCACGGTGCTGGGCAGGAGGGCCGCCTGTGTTCCCAGCTCCTCACAAGCCACCAGAACCTACTTAGAATGAC
CAAAGAGAAACTCCGGAGCTGCCAGGTGGCCCTTCAGGAGCACGAAGCCCTGGAGGAAGCACTGCAAAGCATGTGGTTCTGGGTGAAGGC
CATTCAGGACAGACTGGCCTGTGCAGAGAGCACTCTTGGGAGCAAAGACACCCTGGAGAAACGGCTGTCACAAATACAGGATATTCTCCT
GATGAAAGGTGAAGGGGAAGTTAAGTTGAATATGGCCATTGGCAAGGGGGAACAGGCCTTGAGAAGTAGCAACAAAGAAGGTCAGAGGGT
GATTCAGACTCAGTTAGAGACCCTTAAAGAAGTGTGGGCTGACATCATGAGCTCCTCCGTCCACGCTCAAAGCACTTTAGAGTCTGTGAT
TAGCCAATGGAATGACTATGTAGAGAGGAAAAACCAGTTGGAGCAGTGGATGGAATCAGTGGATCAAAAAATAGAACATCCCTTACAACC
ACAGCCAGGTCTGAAAGAGAAGTTCGTCCTGCTTGACCACCTCCAGTCCATCCTGTCTGAGGCAGAAGATCACACGAGAGCCCTTCACCG
TCTAATTGCGAAGTCCAGGGAGCTCTACGAAAAGACAGAGGATGAGTCTTTCAAGGACACAGCTCAAGAGGAGCTGAAAACACAGTTTAA
TGATATAATGACTGTTGCCAAGGAAAAAATGAGGAAAGTGGAAGAGATTGTGAAAGATCATCTAATGTATTTAGATGCGGTCCACGAGTT
CACAGATTGGCTCCATTCAGCAAAGGAAGAACTTCACCGGTGGTCAGATATGTCTGGAGATTCATCAGCCACCCAGAAAAAGTTATCAAA
AATTAAGGAGCTGATAGATTCCAGAGAGATTGGTGCAAGCCGTCTCAGCAGAGTGGAGTCGCTGGCTCCCGAAGTGAAACAGAACACAAC
TGCCAGTGGGTGTGAGCTCATGCACACGGAGATGCAGGCCCTGCGTGCCGACTGGAAGCAGTGGGAAGACAGTGTATTCCAAACGCAGAG
CTGTTTGGAGAACCTGGTCAGCCAGATGGCCCTTTCGGAGCAGGAATTCTCAGGCCAAGTGGCTCAACTGGAGCAGGCCCTGGAACAGTT
CAGTGCCCTTCTGAAAACCTGGGCTCAGCAGTTAACCCTCCTGGAAGGCAAGAACACGGATGAGGAGATAGTGGAATGCTGGCACAAAGG
ACAAGAGATACTGGATGCTTTGCAAAAAGCAGAGCCTAGAACAGAGGATCTCAAGTCTCAGCTGAATGAACTTTGTCGATTTTCCAGAGA
CCTGAGTACCTACAGTGGAAAAGTTTCTGGCTTGATTAAAGAGTATAATTGTCTTTGTTTGCAAGCATCCAAGGGCTGCCAGAATAAAGA
ACAGATTTTACAGCAAAGATTTCGAAAGGCCTTCAGGGATTTCCAGCAGTGGTTGGTTAATGCAAAAATCACTACCGCCAAGTGTTTTGA
TATACCTCAAAATATAAGTGAAGTTTCAACTAGTCTTCAGAAAATACAGGAGTTTTTGTCAGAAAGTGAAAATGGACAGCACAAGCTAAA
CATGATGCTGTCTAAAGGGGAACTTCTGAGTACCCTGCTGACCAAAGAGAAAGCGAAAGGGATCCAGGCCAAAGTTACAGCTGCAAAAGA
AGATTGGAAAAATTTTCATTCAAATCTCCACCAAAAAGAATCTGCTCTAGAGAATCTAAAGATCCAAATGAAGGACTTTGAAGTAAGTGC
TGAGCCTATCCAGGACTGGCTGAGTAAAACTGAGAAGATGGTCCATGAAAGCAGCAATCGCCTCTATGATCTGCCAGCAAAGAGGAGGGA
GCAGCAGAAGCTCCAGTCTGTCCTTGAGGAAATACACTGCTACGAGCCTCAGCTCAACAGGCTGAAAGAGAAAGCTCAGCAGCTGTGGGA
AGGACAAGCTGCCAGCAAGAGCTTTAGGCACAGAGTGTCGCAGCTGTCTTCTCAGTATCTAGCGCTAAGCAATTTAACAAAGGAGAAAGT
GTCAAGACTGGATAGAATCGTTGCAGAACACAATCAGTTCTCTCTTGGGATTAAAGAATTACAAGACTGGATGACGGATGCGATTCACAT
GCTGGATTCATACTGCCACCCGACATCCGACAAAAGTGTGCTGGACAGCAGGACGCTCAAGCTCGAGGCTCTATTATCAGTCAAACAGGA
AAAAGAGATTCAGATGAAAATGATAGTGACCAGGGGAGAATCTGTCCTTCAGAATACTTCTCCAGAAGGCATTCCCACTATTCAGCAGCA
GCTGCAGAGTGTGAAGGATATGTGGGCATCCCTTTTGTCTGCAGGGATTCGTTGTAAAAGCCAACTCGAAGGAGCTCTCTCCAAGTGGAC
AAGTTATCAGGATGGCGTTCGACAGTTCTCCGGTTGGATGGATAGTATGGAAGCCAACCTGAATGAATCAGAAAGGCAGCATGCGGAGCT
GCGGGATAAAACAACGATGCTCGGAAAAGCCAAGTTATTAAATGAAGAAGTGCTGAGTTACAGCAGCTTGCTGGAGACCATCGAAGTCAA
AGGGGCTGGCATGACAGAACACTATGTCACCCAGCTAGAACTCCAGGATCTACAGGAACGATACAGAGCCATCCAAGAGAGGGCCAAGGA
AGCCGTAACCAAGTCTGAAAAACTTGTCCGCCTGCACCAAGAGTATCAGAGAGACCTAAAGGCATTTGAAGTTTGGTTGGGGCAAGAACA
AGAAAAGCTCGACCAGTATTCAGTTCTTGAAGGTGATGCCCACACTCATGAGACAACATTGCGTGATCTTCAGGAGCTACAGGTACACTG
TGCAGAGGGGCAGGCCCTGTTGAACTCAGTGCTGCACACCAGAGAGGATGTGATCCCATCAGGTATCCCACAGGCAGAGGACCGGGCTTT
AGAGTCTCTCCGGCAAGACTGGCAGGCTTACCAGCACAGGCTGTCCGAGACTCGAACTCAGTTCAATAACGTGGTGAACAAATTGAGGCT
AATGGAGCAAAAGTTTCAGCAAGTAGATGAATGGCTCAAAACAGCAGAGGAGAAAGTTAGTCCCAGGACCAGACGTCAGTCTAACAGGGC
AACCAAGGAGATACAATTACATCAGATGAAGAAGTGGCACGAAGAAGTGACTGCATACAGAGATGAAGTTGAGGAAGTGGGAGCTAGAGC
TCAGGAGATACTGGACGAGAGCCACGTGAACAGCAGAATGGGTTGCCAGGCCACCCAGCTGACTTCCAGATACCAGGCCCTGCTTCTCCA
AGTGCTGGAACAAATAAAATTCCTGGAGGAGGAGATTCAGAGTTTGGAGGAATCAGAATCATCCCTCAGTTCCTATTCTGATTGGTATGG
CTCTACTCATAAAAACTTCAAGAATGTGGCTACCAAGATTGACAAAGTAGATACAGTAATGATGGGGAAGAAATTGAAGACGTTGGAGGT
TTTGCTCAAAGACATGGAGAAAGGTCACAGTTTGCTGAAATCAGCCCGGGAGAAAGGAGAGAGGGCTGTTAAATACTTGGAGGAAGGCGA
GGCAGAGAGGTTAAGAAAGGAGATTCATGATCACATGGAGCAGTTGAAGGAACTGACCAGCACTGTCCGGAAAGAACACATGACGCTGGA
AAAAGGTCTTCATTTAGCAAAGGAATTCTCAGATAAATGCAAAGCACTGACACAGTGGATAGCAGAATACCAGGAAATTCTACATGTTCC
TGAAGAACCCAAAATGGAATTATATGAGAAAAAAGCTCAGTTATCTAAATACAAGTCACTTCAACAAACGGTGCTGTCCCATGAACCATC
AGTAAAGTCAGTGAGAGAGAAGGGTGAAGCTCTTTTGGAACTGGTGCAGGACGTCACTTTAAAGGACAAAATAGATCAACTTCAAAGTGA
TTACCAGGACCTGTGCAGCATAGGAAAGGAGCATGTCTTCAGTCTGGAGGCGAAAGTCAAAGACCATGAAGACTACAACAGTGAGCTCCA
AGAGGTCGAAAAGTGGCTGCTGCAGATGTCTGGCAGACTGGTGGCACCTGACCTCCTGGAGACAAGCAGCCTGGAGACAATCACCCAGCA
ATTGGCCCACCACAAGGCAATGATGGAAGAAATTGCTGGTTTTGAAGACCGTTTGAACAATCTTCAAATGAAAGGTGATACTTTGATTGG
CCAATGTGCAGACCACCTGCAAGCGAAACTTAAACAAAACGTGCATGCTCATCTGCAGGGCACAAAGGACAGCTACTCAGCGATCTGCAG
CACAGCTCAGAGGATGTACCAGAGTTTGGAACACGAACTTCAGAAGCACGTCAGCCGACAAGACACCCTGCAGCAGTGCCAGGCCTGGCT
TTCTGCAGTCCAGCCGGATTTAGAGCCAAGTCCTCAACCACCTCTTAGTAGGGCAGAAGCCATTAAGCAGGTCAAACACTTCAGAGCTTT
GCAAGAGCAGGCAAGGACCTACCTAGATCTCCTTTGCTCCATGTGTGACCTGTCAAATGCTTCGGTGAAAACCACAGCAAAAGACATTCA
ACAAACAGAGCAAACGATTGAACAAAAGCTTGTCCAGGCCCAGAACTTAACTCAGGGCTGGGAAGAGATCAAGCACCTGAAGTCTGAGCT
CTGGATTTACCTGCAAGATGCTGATCAGCAACTGCAGAACATGAAGAGGAGGCACTCTGAGCTGGAGCTGAACATTGCACAGAACATGGT
TTCACAAGTTAAGGATTTTGTTAAGAAACTACAGAGCAAACAGGCATCCGTGAACACCATAATAGAAAAGGTGAATAAGTTAACAAAGAA
GGAGGAATCGCCTGAACACAAGGAAATAAATCATTTAAATGATCAGTGGCTCGATTTGTGCCGTCAGTCTAACAACCTGTGCTTGCAAAG
GGAAGAGGATCTTCAGAGAACAAGAGATTACCATGACTGTATGAATGTTGTTGAAGTGTTCCTAGAAAAATTTACTACAGAATGGGATAA
CTTGGCCAGATCTGATGCAGAGAGTACAGCTGTCCACCTGGAAGCTTTGAAAAAGTTAGCATTGGCATTGCAGGAGAGAAAGTATGCTAT
TGAAGATCTGAAAGATCAAAAGCAGAAAATGATAGAGCATCTGAATTTAGATGACAAGGAGTTAGTCAAAGAACAGACGAGTCATTTAGA
GCAACGTTGGTTTCAGCTTGAGGACCTCATTAAAAGGAAAATCCAAGTGTCAGTCACCAACTTGGAGGAGTTAAATGTGGTGCAGTCCAG
ATTTCAGGAGCTAATGGAGTGGGCAGAAGAGCAACAACCCAACATCGCCGAGGCCCTTAAGCAGAGCCCTCCTCCAGATATGGCTCAGAA
CCTTCTCATGGATCACCTGGCCATCTGCAGTGAACTGGAGGCCAAGCAGATGCTCCTGAAATCGCTTATAAAGGACGCAGACAGGGTCAT
GGCAGATCTTGGTCTCAATGAGCGACAGGTCATCCAGAAGGCTCTCTCTGATGCACAAAGCCACGTGAATTGTCTCAGTGACTTAGTGGG
CCAGCGAAGAAAGTACTTAAACAAAGCCTTGTCCGAGAAAACCCAGTTTCTCATGGCAGTGTTCCAGGCCACCAGCCAAATTCAGCAACA
TGAGCGAAAGATAATGTTCCGTGAACACATCTGTCTGTTACCAGATGATGTGAGCAAACAAGTCAAAACATGTAAGAGTGCACAAGCCAG
CCTCAAGACTTACCAAAATGAAGTCACTGGACTTTGGGCCCAGGGTCGCGAACTAATGAAGGAAGTCACAGAGCAGGAAAAGAGTGAAGT
GCTGGGGAAGCTTCAGGAATTGCAGAGTGTCTATGACAGTGTTTTACAAAAGTGCAGTCACCGGTTACAAGAACTAGAGAAGAATTTGGT
TTCTAGGAAGCATTTTAAGGAAGATTTTGATAAAGCTTGCCACTGGCTAAAACAAGCAGATATTGTTACATTTCCTGAAATCAACCTAAT
GAATGAGAGTTCTGAGCTTCATACACAACTGGCTAAATACCAAAACATTCTTGAACAATCTCCAGAATATGAAAATCTTCTACTTACGCT
GCAGAGAACTGGGCAGACCATATTACCATCGCTGAATGAAGTCGATCATTCCTACCTCAGTGAAAAGCTAAATGCTTTGCCTCGACAATT
TAATGTAATTGTTGCCTTGGCTAAAGACAAGTTCTATAAAGTCCAGGAAGCAATTCTTGCTCGGAAGGAATATGCTTCCTTGATTGAGTT
GACAACCCAGTCTCTGAGTGAACTTGAAGCCCAATTCTTGAGGATGAGCAAAGTTCCCACCGACCTGGCCGTTGAGGAGGCTCTTTCTCT
GCAAGATGGTTGCAGAGCCATTCTGGACGAGGTGGCGGGCCTTGGGGAGGCGGTGGATGAACTGAACCAGAAAAAAGAAGGTTTTCGCAG
CACAGGTCAGCCTTGGCAGCCAGACAAGATGCTGCACCTTGTCACCTTATATCACAGGCTGAAGCGACAAACAGAACAGAGGGTTAGCTT
ATTAGAAGACACCACCAGTGCTTACCAAGAACACGAGAAGATGTGCCAACAGCTGGAGAGACAACTGAAGTCTGTAAAAGAGGAGCAGTC
CAAAGTGAATGAGGAAACGCTGCCTGCAGAGGAGAAGCTCAAAATGTATCACTCCCTGGCAGGAAGTCTCCAGGACTCAGGGATTGTACT
GAAACGAGTAACCATACATCTTGAAGATCTTGCCCCACACCTTGACCCCTTGGCTTATGAGAAAGCCAGGCATCAGATCCAGTCCTGGCA
AGGGGAGTTAAAACTGTTGACTTCTGCCATTGGTGAGACGGTGACAGAATGTGAGAGCCGAATGGTGCAGAGTATAGACTTCCAGACTGA
GATGAGTCGCTCCCTGGACTGGCTGAGGAGAGTGAAGGCAGAGCTCAGTGGGCCGGTGTACCTAGACCTCAACCTGCAGGACATCCAAGA
GGAAATCAGAAAAATCCAAATTCATCAGGAAGAGGTCCAGTCCAGCTTGAGAATCATGAATGCGCTGAGTCACAAGGAAAAGGAGAAGTT
CACAAAGGCCAAGGAGCTGATTTCTGCGGATTTAGAACACAGCCTCGCTGAGCTCTCAGAGCTGGATGGAGACATCCAGGAAGCCTTACG
CACCAGACAGGCTACCTTGACTGAAATATATAGCCAGTGTCAAAGGTATTATCAGGTATTTCAAGCAGCCAATGACTGGCTTGAGGATGC
CCAAGAATTGTTACAGCTGGCAGGCAATGGCCTAGACGTGGAGAGCGCAGAGGAAAATCTCAAAAGCCACATGGAATTTTTCAGTACAGA
GGATCAGTTCCATAGTAACCTGGAGGAGCTCCACAGCCTGGTAGCCACCCTGGACCCACTCATCAAGCCAACCGGCAAAGAAGACCTAGA
ACAGAAAGTGGCTTCTCTGGAACTCAGGAGCCAGAGGATGAGCCGGGACTCTGGTGCCCAAGTGGATCTCTTGCAGAGATGCACAGCTCA
ATGGCACGATTACCAGAAAGCAAGGGAAGAGGTTATTGAATTGATGAATGATACAGAAAAGAAATTGTCTGAGTTTTCTTTGTTGAAGAC
TTCGTCTAGTCATGAAGCGGAAGAAAAATTGTCAGAACACAAGGCTTTAGTGTCAGTGGTTAACTCTTTCCATGAGAAAATTGTGGCCCT
TGAGGAAAAAGCTTCACAACTGGAGAAAACCGGAAATGATGCCAGCAAAGCCACCCTGAGCAGGTCAATGACCACCGTCTGGCAGCGCTG
GACACGCCTTCGAGCTGTGGCCCAGGACCAGGAGAAGATCCTGGAAGATGCAGTGGATGAGTGGACGGGCTTTAACAACAAGGTTAAAAA
GGCCACTGAAATGATTGATCAGCTGCAAGATAAGTTACCTGGAAGTTCAGCAGAGAAAGCATCGAAAGCAGAGCTCTTAACTCTTCTTGA
ATACCACGACACGTTCGTTCTGGAGCTGGAGCAGCAGCAGTCGGCCTTGGGCATGCTGCGGCAGCAAACCCTGAGCATGCTCCAGGATGG
AGCCGCCCCAACCCCTGGGGAAGAGCCTCCGCTCATGCAGGAAATCACCGCCATGCAAGATCGGTGCCTGAACATGCAGGAGAAAGTGAA
GACTAATGGAAAGTTGGTGAAGCAAGAGCTGAAGGACCGAGAAATGGTGGAGACTCAGATCAATTCTGTGAAATGTTGGGTTCAGGAAAC
GAAAGAATATTTAGGGAATCCAACAATAGAAATAGATGCTCAACTTGAAGAACTTCAGATTCTCCTAACAGAAGCCACAAATCACCGACA
GAACATTGAAAAAATGGCAGAAGAACAGAAGGAGAAGTACTTAGGTCTTTATACCATATTACCTTCTGAACTCTCCCTTCAGTTGGCTGA
AGTGGCGTTAGATCTAAAGATCCGAGATCAGATCCAAGACAAAATAAAAGAAGTTGAGCAGAGCAAGGCCACGAGCCAGGAACTCAGCCG
GCAAATTCAGAAGTTAGCTAAAGACCTCACAACTATTCTAACTAAGCTGAAAGCGAAGACAGATAATGTAGTTCAAGCTAAAACTGACCA
AAAGGTGCTGGGAGAGGAATTAGATGGCTGTAATTCAAAGTTAATGGAATTAGATGCAGCAGTACAGAAATTCTTGGAACAGAATGGCCA
ACTGGGTAAGCCACTGGCCAAGAAGATAGGAAAACTGACTGAACTTCACCAGCAGACCATTAGACAAGCTGAGAATCGGCTCTCCAAGCT
CAATCAGGCAGCATCACATTTAGAAGAATACAATGAAATGCTTGAATTAATTTTGAAGTGGATTGAAAAAGCTAAAGTCTTGGCTCATGG
AACTATTGCATGGAATTCTGCAAGCCAGCTTCGGGAACAATATATTTTGCATCAGACCCTGCTAGAAGAATCCAAAGAAATTGACAGTGA
GCTGGAAGCAATGACTGAGAAATTACAGTACCTCACTAGCGTGTACTGTACAGAAAAAATGTCTCAGCAAGTGGCAGAACTGGGACGGGA
GACTGAGGAGTTGCGACAGATGATCAAAATTCGTTTGCAGAACCTCCAAGATGCAGCTAAGGATATGAAAAAATTTGAAGCAGAGTTGAA
AAAGTTACAAGCTGCCTTGGAGCAAGCCCAGGCAACACTGACTTCTCCAGAAGTTGGACGTCTCAGTCTCAAGGAGCAGCTCTCTCATCG
GCAGCATTTGTTGTCTGAGATGGAGTCACTGAAGCCGAAGGTGCAAGCAGTGCAGCTCTGCCAGAGTGCCCTCCGGATCCCCGAGGATGT
GGTTGCCAGCTTACCTCTCTGTCATGCTGCTCTGCGGCTGCAGGAAGAGGCCAGCCGGCTGCAGCACACCGCCATCCAGCAGTGTAACAT
CATGCAGGAAGCTGTGGTACAATATGAACAATATGAGCAAGAAATGAAACATCTCCAGCAACTGATAGAAGGAGCTCACAGAGAGATTGA
GGATAAACCTGTTGCCACCAGTAACATACAGGAGCTGCAGGCTCAGATTTCTCGGCATGAGGAGCTGGCGCAGAAAATTAAGGGCTACCA
GGAGCAGATCGCTTCTTTGAATTCCAAGTGCAAGATGCTGACGATGAAAGCCAAGCACGCCACCATGCTGCTGACGGTGACCGAGGTCGA
GGGGCTGGCGGAAGGGACAGAGGACCTGGATGGGGAGCTCCTCCCCACGCCTTCGGCCCACCCCTCTGTGGTCATGATGACTGCAGGTCG
CTGTCACACTTTGCTGTCACCGGTCACTGAGGAGTCTGGGGAGGAGGGAACCAACAGTGAGATTTCCTCTCCACCTGCCTGTCGCTCCCC
TTCACCTGTGGCTAATACAGATGCTTCTGTTAACCAGGACATTGCATATTACCAAGCCTTGTCTGCTGAGAGGTTGCAGACAGATGCTGC
AAAAATTCACCCCAGCACATCCGCATCCCAGGAGTTCTATGAACCGGGATTGGAGCCATCCGCTACTGCCAAACTGGGTGATTTGCAGCG
TTCTTGGGAAACCTTAAAGAATGTGATCAGTGAGAAGCAGCGCACACTCTATGAAGCTTTGGAACGCCAGCAGAAGTACCAGGACTCCCT
CCAGTCCATCTCTACGAAGATGGAGGCCATTGAGCTGAAACTCAGTGAGAGCCCAGAGCCTGGCAGGAGTCCAGAAAGCCAGATGGCTGA
ACATCAGGCATTGATGGATGAGATTCTCATGCTCCAGGATGAAATCAATGAGCTCCAGTCCTCTCTCGCAGAGGAGCTGGTATCCGAGTC
TTGTGAGGCCGACCCTGCGGAGCAGCTGGCCTTGCAGTCCACGCTCACTGTCTTAGCCGAGCGAATGTCCACCATCAGGATGAAAGCCTC
GGGGAAACGGCAGCTTTTGGAGGAGAAGTTGAATGATCAGCTGGAGGAACAAAGGCAGGAACAGGCCCTGCAGAGGTATCGCTGTGAAGC
CGATGAGCTGGACAGCTGGCTCTTGAGTACCAAGGCCACTCTGGACACTGCGCTGAGTCCACCCAAGGAGCCCATGGACATGGAGGCCCA
GCTTATGGACTGCCAGAATATGCTGGTGGAAATAGAGCAGAAGGTGGTGGCTTTATCAGAACTGTCAGTCCACAATGAGAACCTGCTGCT
GGAGGGCAAAGCTCACACCAAGGACGAGGCCGAGCAGCTGGCTGGAAAGCTGAGAAGGCTCAAGGGGAGCCTGCTGGAGCTGCAGAGAGC
CCTGCATGATAAGCAGCTCAACATGCAGGGAACAGCACAGGAGAAGGAGGAGAGCGATGTTGACCTAACAGCCACGCAGAGCCCCGGCGT
CCAGGAATGGCTGGCCCAAGCTCGCACCACATGGACCCAGCAGCGGCAGAGCAGTCTCCAGCAACAAAAAGAGTTAGAACAGGAATTAGC
CGAGCAGAAGAGTCTCCTTCGCTCAGTAGCCAGTCGTGGAGAGGAGATTCTAATTCAACATTCGGCGGCAGAGACCTCTGGTGATGCTGG
CGAAAAACCTGATGTGTTATCCCAGGAGTTGGGGATGGAAGGGGAGAAATCATCCGCTGAAGACCAGATGAGAATGAAATGGGAAAGCCT
ACATCAAGAATTTAGTACCAAGCAGAAACTACTACAGAATGTTCTGGAACAGGAACAAGAGCAAGTGCTTTATAGCAGGCCAAATCGACT
CTTGTCTGGTGTGCCACTGTACAAAGGGGACGTGCCAACCCAAGATAAATCTGCAGTTACATCTTTGCTGGATGGACTGAACCAAGCCTT
CGAGGAGGTTTCATCCCAGAGTGGAGGGGCAAAGAGGCAGAGTATACACTTGGAGCAGAAGTTGTATGATGGAGTCTCAGCCACCTCTAC
TTGGTTGGATGACGTTGAAGAACGTTTATTTGTTGCCACAGCACTTTTACCAGAAGAAACAGAGACTTGTCTCTTCAACCAAGAGATTCT
TGCCAAAGACATTAAGGAAATGTCTGAAGAAATGGATAAGAACAAAAACTTGTTTTCCCAAGCTTTTCCAGAGAATGGTGATAATCGAGA
TGTTATTGAAGATACTTTGGGTTGTCTTTTGGGCAGGTTATCCTTGCTAGACTCAGTAGTGAATCAACGATGTCATCAGATGAAAGAAAG
ACTTCAGCAAATACTAAATTTCCAGAATGATCTGAAAGTGCTGTTTACATCACTGGCTGACAACAAATACATCATTCTGCAAAAACTGGC
AAATGTGTTTGAACAGCCCGTAGCAGAACAAATAGAGGCAATACAACAGGCTGAAGATGGACTCAAAGAATTTGATGCAGGAATCATTGA
ATTAAAGAGGCGTGGTGACAAGCTACAGGTCGAGCAGCCGTCCATGCAAGAACTCTCCAAGCTCCAGGACATGTATGATGAGCTGATGAT
GATCATTGGCTCCCGGAGGAGTGGTCTGAATCAGAACCTTACACTCAAGAGTCAGTATGAGAGGGCCCTACAAGATCTGGCTGACCTGCT
AGAAACTGGTCAGGAGAAGATGGCAGGAGACCAGAAAATCATCGTGTCTTCCAAAGAGGAAATCCAGCAACTACTTGACAAACATAAGGA
ATACTTTCAGGGCCTGGAATCTCATATGATCTTGACTGAAACACTCTTCAGAAAGATAATCAGCTTTGCAGTCCAAAAGGAAACCCAGTT
CCATACAGAGCTGATGGCTCAGGCTTCTGCTGTACTGAAACGGGCTCACAAGAGGGGTGTGGAGCTGGAGTACATTCTAGAGACGTGGTC
CCATCTGGATGAGGACCAGCAGGAGCTCAGCAGACAGCTGGAGGTGGTGGAAAGCAGCATCCCAAGCGTGGGTCTGGTGGAGGAGAACGA
GGACAGGCTTATTGACCGCATAACACTCTACCAGCATTTAAAATCTAGCCTTAATGAATACCAGCCCAAATTATATCAAGTATTAGATGA
TGGGAAACGACTTCTGATATCCATCAGCTGCTCAGATCTAGAAAGCCAACTAAATCAACTTGGAGAGTGCTGGCTAAGTAACACCAATAA
AATGTCTAAGGAACTTCACAGACTGGAAACAATATTGAAACACTGGACCAGATATCAAAGTGAATCTGCAGATCTAATTCACTGGTTACA
ATCTGCAAAAGACCGGCTAGAATTTTGGACTCAGCAATCTGTGACAGTCCCACAAGAGCTGGAAATGGTCCGTGATCATCTAAATGCTTT
CCTGGAGTTTTCTAAAGAAGTGGATGCCCAATCTTCCCTGAAATCATCTGTTCTGAGTACTGGAAATCAGCTCCTTCGACTAAAAAAGGT
GGACACAGCCACGCTGCGCTCTGAGCTGTCGCGCATTGATAGCCAGTGGACTGACCTGCTAACCAATATCCCAGCCGTCCAGGAGAAGCT
CCACCAGCTCCAGATGGATAAACTGCCTTCCCGCCATGCCATTTCTGAAGTCATGAGTTGGATTTCTCTAATGGAAAATGTTATTCAGAA
GGATGAAGATAATATTAAAAATTCCATAGGTTACAAGGCAATTCATGAATACCTTCAGAAATATAAGGGTTTTAAGATAGACATTAACTG
TAAACAGCTGACAGTGGATTTTGTGAACCAGTCCGTGCTACAAATCAGCAGTCAGGATGTGGAAAGTAAGCGTAGTGATAAGACTGATTT
TGCTGAGCAACTTGGAGCAATGAATAAAAGTTGGCAAATTCTGCAAGGTCTAGTAACTGAGAAGATCCAGCTGTTGGAAGGCTTATTGGA
ATCTTGGTCAGAATATGAAAATAATGTACAATGTCTGAAAACATGGTTTGAAACCCAGGAAAAGAGACTAAAACAACAGCATCGAATTGG
AGATCAGGCTTCTGTTCAAAATGCACTGAAAGACTGTCAGGATCTGGAAGATTTGATTAAAGCAAAAGAAAAAGAAGTAGAGAAAATTGA
GCAGAATGGACTTGCTTTGATTCAGAACAAGAAAGAAGACGTCTCTAGCATTGTCATGAGCACACTGCGAGAGCTCGGCCAAACCTGGGC
AAATTTAGATCACATGGTTGGACAATTAAAGATACTGCTGAAATCAGTGCTTGACCAATGGAGTAGTCACAAAGTGGCCTTTGACAAGAT
AAACAGTTACCTCATGGAGGCCAGATACTCTCTTTCCCGATTCCGTCTGCTGACTGGCTCCTTAGAAGCTGTGCAAGTTCAGGTGGACAA
TCTTCAGAATCTCCAAGATGATCTGGAAAAACAGGAAAGGAGCTTACAGAAATTTGGCTCTATCACCAACCAATTATTAAAAGAGTGTCA
CCCACCCGTGACAGAAACTCTTACCAATACACTGAAAGAAGTCAACATGAGATGGAATAACTTGCTGGAAGAGATTGCTGAGCAGCTACA
GTCCAGCAAGGCCCTACTTCAGCTTTGGCAAAGATACAAGGACTACTCCAAACAGTGTGCTTCGACAGTTCAGCAGCAGGAGGATCGAAC
CAATGAGCTGTTGAAGGCAGCCACAAACAAGGACATTGCCGATGATGAGGTTGCCACATGGATTCAAGATTGCAACGACCTCCTCAAAGG
ACTGGGCACAGTTAAAGATTCCCTCTTTTTTCTCCATGAGCTGGGAGAGCAACTGAAGCAACAAGTGGATGCTTCCGCAGCATCAGCTAT
TCAATCGGATCAACTCTCTTTGAGTCAACACTTGTGTGCCCTGGAGCAAGCTCTCTGCAAACAGCAGACTTCATTACAGGCTGGAGTTCT
TGATTATGAAACCTTTGCCAAGAGTTTAGAAGCTTTGGAGGCCTGGATAGTGGAAGCTGAAGAAATACTACAAGGGCAGGACCCTAGCCA
CTCATCTGACCTCTCCACAATCCAGGAAAGGATGGAAGAACTTAAGGGACAGATGTTAAAATTCAGCAGCATGGCTCCAGATTTAGACCG
TCTAAATGAGCTTGGATATAGGTTACCCTTGAATGATAAGGAAATCAAAAGAATGCAGAATCTGAACCGCCATTGGTCTCTGATCTCCTC
TCAGACTACAGAAAGATTCAGCAAGTTGCAGTCATTTTTGCTACAACATCAGACTTTCTTGGAAAAATGTGAAACATGGATGGAATTCCT
AGTTCAGACAGAACAAAAGTTAGCAGTAGAGATTTCAGGAAATTATCAGCACCTTTTGGAACAGCAGAGAGCACACGAGTTGTTTCAAGC
CGAGATGTTCAGTCGTCAGCAGATTTTGCACTCAATCATTATTGATGGGCAACGTCTTCTAGAACAAGGTCAAGTTGATGACAGGGATGA
ATTCAACCTGAAATTGACACTCCTCAGTAATCAATGGCAGGGAGTGATTCGCAGGGCCCAGCAGAGGCGGGGGATCATTGACAGCCAGAT
TCGCCAGTGGCAGCGCTATAGGGAGATGGCAGAAAAGCTTCGTAAATGGTTGGTTGAAGTGTCCTACCTCCCCATGAGTGGTCTCGGAAG
TGTTCCTATACCACTGCAACAAGCAAGGACCCTCTTTGATGAAGTGCAGTTCAAAGAAAAAGTGTTTCTGCGGCAACAAGGCAGCTACAT
CCTGACTGTGGAGGCTGGCAAGCAACTCCTTCTCTCGGCGGACAGTGGCGCTGAGGCCGCCTTGCAGGCCGAACTCGCTGAAATCCAAGA
GAAATGGAAATCAGCCAGCATGCGGCTGGAAGAACAGAAGAAAAAACTAGCCTTCTTGTTGAAAGACTGGGAAAAATGTGAGAAAGGAAT
AGCAGATTCCCTGGAGAAACTACGAACTTTCAAAAAGAAGCTTTCGCAGTCTCTCCCGGATCACCATGAAGAGCTCCATGCAGAACAAAT
GCGTTGCAAGGAATTAGAAAATGCAGTTGGGAGCTGGACAGATGACTTGACCCAGTTGAGCCTGCTGAAGGACACCCTCTCTGCCTATAT
CAGTGCTGATGATATCTCCATTCTTAATGAACGCGTAGAGCTTCTGCAAAGGCAGTGGGAAGAACTATGCCACCAGCTCTCCTTAAGGCG
GCAGCAAATAGGTGAAAGATTGAATGAATGGGCAGTCTTCAGTGAAAAGAACAAGGAACTCTGTGAGTGGTTGACTCAAATGGAAAGCAA
AGTTTCTCAGAATGGAGACATTCTCATTGAAGAAATGATAGAGAAGCTCAAGAAGGATTATCAAGAGGAAATTGCTATTGCTCAAGAGAA
CAAAATACAGCTCCAACAAATGGGAGAACGACTTGCTAAAGCCAGCCATGAAAGCAAAGCATCTGAGATTGAATACAAGCTGGGAAAGGT
CAACGACCGGTGGCAGCATCTCCTGGACCTCATTGCAGCCAGGGTGAAGAAGCTGAAGGAGACCCTGGTAGCCGTGCAGCAGCTTGATAA
GAACATGAGCAGCCTGAGGACCTGGCTCGCTCACATCGAGTCAGAGCTGGCCAAGCCAATAGTCTACGATTCCTGTAACTCGGAAGAAAT
ACAGAGAAAGCTTAATGAGCAGCAGGAGCTTCAGAGAGACATAGAGAAGCACAGTACAGGTGTTGCATCTGTCCTCAACCTGTGTGAAGT
CCTGCTGCACGACTGTGACGCCTGTGCCACTGATGCCGAGTGTGACTCTATACAGCAGGCTACGAGAAACCTGGACCGGCGGTGGAGAAA
CATTTGTGCTATGTCCATGGAAAGGAGGCTGAAAATCGAAGAGACGTGGCGATTGTGGCAGAAATTTCTGGATGACTATTCACGTTTTGA
AGATTGGCTGAAGTCTTCAGAAAGGACAGCTGCTTTTCCCAGCTCTTCTGGGGTGATCTATACAGTTGCCAAGGAAGAACTAAAGAAATT
TGAGGCTTTCCAGCGACAGGTCCACGAGTGCCTGACGCAGCTGGAACTGATCAACAAGCAGTACCGCCGCCTGGCCAGGGAGAACCGCAC
TGATTCAGCATGTAGCCTCAAACAGATGGTTCACGAAGGCAACCAGAGATGGGACAACCTGCAAAAGCGTGTCACCTCCATCTTGCGCAG
ACTCAAGCATTTTATTGGCCAGCGTGAGGAGTTTGAGACTGCGCGGGACAGCATTCTGGTCTGGCTCACAGAGATGGATCTGCAGCTCAC
TAATATTGAACATTTTTCTGAGTGTGATGTTCAAGCTAAAATAAAGCAACTCAAGGCCTTCCAGCAGGAAATTTCACTGAACCACAATAA
GATTGAGCAGATAATTGCCCAAGGAGAACAGCTGATAGAAAAGAGTGAGCCCTTGGATGCAGCGATCATCGAGGAGGAACTAGATGAGCT
CCGACGGTACTGCCAGGAGGTCTTCGGGCGTGTGGAAAGATACCATAAGAAACTGATCCGCCTGCCTCTCCCAGACGATGAGCACGACCT
CTCAGACAGGGAGCTGGAGCTGGAAGACTCTGCAGCTCTGTCGGACCTGCACTGGCACGACCGCTCTGCAGACAGCCTGCTTTCTCCACA
GCCTTCCTCCAATCTCTCCCTCTCGCTCGCTCAGCCCCTCCGGAGCGAGCGGTCAGGACGAGACACCCCGGCTAGTGTGGACTCCATCCC
CCTGGAGTGGGATCACGACTATGACCTCAGTCGGGACCTGGAGTCTGCAATGTCCAGAGCTCTGCCCTCTGAGGATGAAGAAGGTCAGGA
TGACAAAGATTTCTACCTCCGGGGAGCTGTTGGCTTATCAGGGGACCACAGTGCCCTAGAGTCACAGATCCGACAACTGGGCAAAGCCCT
GGATGATAGCCGTTTTCAGATACAGCAAACCGAAAATATCATTCGCAGCAAAACTCCCACGGGGCCGGAGCTAGACACCAGCTACAAAGG
CTACATGAAACTGCTGGGCGAATGCAGTAGCAGTATAGACTCCGTGAAGAGACTGGAGCACAAACTGAAGGAGGAAGAGGAGAGCCTTCC
TGGCTTTGTTAACCTGCATAGTACCGAAACCCAAACGGCTGGTGTGATTGACCGATGGGAGCTTCTCCAGGCCCAGGCATTGAGCAAGGA
GTTGAGGATGAAGCAGAACCTCCAGAAGTGGCAGCAGTTTAACTCAGACTTGAACAGCATCTGGGCCTGGCTGGGGGACACGGAGGAGGA
GTTGGAACAGCTCCAGCGTCTGGAACTCAGCACTGACATCCAGACCATCGAGCTCCAGATCAAAAAGCTCAAGGAGCTCCAGAAAGCTGT
GGACCACCGCAAAGCCATCATCCTCTCCATCAATCTCTGCAGCCCTGAGTTCACCCAGGCTGACAGCAAGGAGAGCCGGGACCTGCAGGA
TCGCTTGTCGCAGATGAATGGGCGCTGGGACCGAGTGTGCTCTCTGCTGGAGGAGTGGCGGGGCCTGCTGCAGGATGCCCTGATGCAGTG
CCAGGGTTTCCATGAAATGAGCCATGGTTTGCTTCTTATGCTGGAGAACATTGACAGAAGGAAAAATGAAATTGTCCCTATTGATTCTAA
CCTTGATGCAGAGATACTTCAGGACCATCACAAACAGCTTATGCAAATAAAGCATGAGCTGTTGGAATCCCAACTCAGAGTAGCCTCTTT
GCAAGACATGTCTTGCCAACTACTGGTGAATGCTGAAGGAACAGACTGTTTAGAAGCCAAAGAAAAAGTCCATGTTATTGGAAATCGGCT
CAAACTTCTCTTGAAGGAGGTCAGTCGTCATATCAAGGAACTGGAGAAGTTATTAGACGTGTCAAGTAGTCAGCAGGATTTGTCTTCCTG
GTCTTCTGCTGATGAACTGGACACCTCAGGGTCTGTGAGTCCCACATCAGGAAGGAGCACCCCAAACAGACAGAAAACGCCACGAGGCAA
GTGTAGTCTCTCACAGCCTGGACCCTCTGTCAGCAGTCCACATAGCAGGTCCACAAAAGGTGGCTCCGATTCCTCCCTTTCTGAGCCAGG
GCCAGGTCGGTCCGGCCGCGGCTTCCTGTTCAGAGTCCTCCGAGCAGCTCTTCCCCTTCAGCTTCTCCTGCTCCTCCTCATCGGGCTTGC
CTGCCTTGTACCAATGTCAGAGGAAGACTACAGCTGTGCCCTCTCCAACAACTTTGCCCGGTCATTCCACCCCATGCTCAGATACACGAA
TGGCCCTCCTCCACTCTGAACTAAGCAGATGCCATCTGCAGAAGTGCTGGTAGCATAAGGAGGATCGGGTCATAAGCAATCCCAAACTAC
CAACAAGAGGACCTTGATCTTGGCGAAAGCCCTCGGTGTGGCAGCTTTAGCCCTCCTCCAGATCACATGTGTGCAAATTATGGCTTCAGA
GGTGGAAGATAAACAGTGACGGGGGAACAAACAGACAACAAGAAGGTTTGGAAGAAATCTGGTTTGAGACTCTGAACCTTAGCACTAAGG
AGATTGAGTAAGGACCTCCAAAGTTCCCCGGACTCATGAATTCTGGGCCCTTGGCCCATTCTGTGCACAGCCAAGGACTTCAGTAGACCA
TCTGGGCAGCTTTCCCATGGTGCTGCTCCAACCATCAGATAAATGACCCTCCCAAGCACCATGTCAGTGTCGTACAATCTACCAACCAAC
CAGTGCTGAAGAGATTTTAGAACCTTGTAACATACAATTTTTAAGAGCTTATATGGCAGCTTCCTTTTTACCTTGTTTTCCTTTGGGGCA
TGATGTTTTAACCTTTGCTTTAGAAGCACAAGCTGTAAATCTAAAAGGCACTTTTTTTTAGAGGTATAAAGAAAAACTAGATGTAATAAA
TAAGATCATGGAAGGCTTTATGTGAAAAAAGTTGAATGTTATAGTAAAAAAAAAAAGATATTTATGTATGTACAGTTTGCTAAAGCCAAG

>In-frame_ENST00000377252_ENST00000367255_TCGA-A8-A07R-01A_PLXDC2_chr10_20290915_+_SYNE1_chr6_152793548_length(amino acids)=8455AA_start in transcript=841_stop in transcript=26208
MARFPKADLAAAGVMLLCHFFTDQFQFADGKPGDQILDWQYGVTQAFPHTEEEVEVDSHAYSHRWKRNLDFLKAVDTNRASVGQDSPEPR
SFTDLLLDDGQDNNTQIEDLLQNTDAHKRAFHEIYRTRSVNGIPVPPDQLEDMAERFHFVSSTSELHLMKMEFLELKYRLLSLLVLAESK
LKSWIIKYGRRESVEQLLQNYVSFIENSKFFEQYEVTYQILKQTAEMYVKADGSVEEAENVMKFMNETTAQWRNLSVEVRSVRSMLEEVI
SNWDRYGNTVASLQAWLEDAEKMLNQSENAKKDFFRNLPHWIQQHTAMNDAGNFLIETCDEMVSRDLKQQLLLLNGRWRELFMEVKQYAQ
ADEMDRMKKEYTDCVVTLSAFATEAHKKLSEPLEVSFMNVKLLIQDLEDIEQRVPVMDAQYKIITKTAHLITKESPQEEGKEMFATMSKL
KEQLTKVKECYSPLLYESQQLLIPLEELEKQMTSFYDSLGKINEIITVLEREAQSSALFKQKHQELLACQENCKKTLTLIEKGSQSVQKF
VTLSNVLKHFDQTRLQRQIADIHVAFQSMVKKTGDWKKHVETNSRLMKKFEESRAELEKVLRIAQEGLEEKGDPEELLRRHTEFFSQLDQ
RVLNAFLKACDELTDILPEQEQQGLQEAVRKLHKQWKDLQGEAPYHLLHLKIDVEKNRFLASVEECRTELDRETKLMPQEGSEKIIKEHR
VFFSDKGPHHLCEKRLQLIEELCVKLPVRDPVRDTPGTCHVTLKELRAAIDSTYRKLMEDPDKWKDYTSRFSEFSSWISTNETQLKGIKG
EAIDTANHGEVKRAVEEIRNGVTKRGETLSWLKSRLKVLTEVSSENEAQKQGDELAKLSSSFKALVTLLSEVEKMLSNFGDCVQYKEIVK
NSLEELISGSKEVQEQAEKILDTENLFEAQQLLLHHQQKTKRISAKKRDVQQQIAQAQQGEGGLPDRGHEELRKLESTLDGLERSRERQE
RRIQVTLRKWERFETNKETVVRYLFQTGSSHERFLSFSSLESLSSELEQTKEFSKRTESIAVQAENLVKEASEIPLGPQNKQLLQQQAKS
IKEQVKKLEDTLEEDIKTMEMVKTKWDHFGSNFETLSVWITEKEKELNALETSSSAMDMQISQIKVTIQEIESKLSSIVGLEEEAQSFAQ
FVTTGESARIKAKLTQIRRYGEELREHAQCLEGTILGHLSQQQKFEENLRKIQQSVSEFEDKLAVPIKICSSATETYKVLQEHMDLCQAL
ESLSSAITAFSASARKVVNRDSCVQEAAALQQQYEDILRRAKERQTALENLLAHWQRLEKELSSFLTWLERGEAKASSPEMDISADRVKV
EGELQLIQALQNEVVSQASFYSKLLQLKESLFSVASKDDVKMMKLHLEQLDERWRDLPQIINKRINFLQSVVAEHQQFDELLLSFSVWIK
LFLSELQTTSEISIMDHQVALTRHKDHAAEVESKKGELQSLQGHLAKLGSLGRAEDLHLLQGKAEDCFQLFEEASQVVERRQLALSHLAE
FLQSHASLSGILRQLRQTVEATNSMNKNESDLIEKDLNDALQNAKALESAAVSLDGILSKAQYHLKIGSSEQRTSCRATADQLCGEVERI
QNLLGTKQSEADALAVLKKAFQDQKEELLKSIEDIEERTDKERLKEPTRQALQQRLRVFNQLEDELNSHEHELCWLKDKAKQIAQKDVAF
APEVDREINRLEVTWDDTKRLIHENQGQCCGLIDLMREYQNLKSAVSKVLENASSVIVTRTTIKDQEDLKWAFSKHETAKNKMNYKQKDL
DNFTSKGKHLLSELKKIHSSDFSLVKTDMESTVDKWLDVSEKLEENMDRLRVSLSIWDDVLSTRDEIEGWSNNCVPQMAENISNLDNHLR
AEELLKEFESEVKNKALRLEELHSKVNDLKELTKNLETPPDLQFIEADLMQKLEHAKEITEVAKGTLKDFTAQSTQVEKFINDITTWFTK
VEESLMNCAQNETCEALKKVKDIQKELQSQQSNISSTQENLNSLCRKYHSAELESLGRAMTGLIKKHEAVSQLCSKTQASLQESLEKHFS
ESMQEFQEWFLGAKAAAKESSDRTGDSKVLEAKLHDLQNILDSVSDGQSKLDAVTQEGQTLYAHLSKQIVSSIQEQITKANEEFQAFLKQ
CLKDKQALQDCASELGSFEDQHRKLNLWIHEMEERFNTENLGESKQHIPEKKNEVHKVEMFLGELLAARESLDKLSQRGQLLSEEGHGAG
QEGRLCSQLLTSHQNLLRMTKEKLRSCQVALQEHEALEEALQSMWFWVKAIQDRLACAESTLGSKDTLEKRLSQIQDILLMKGEGEVKLN
MAIGKGEQALRSSNKEGQRVIQTQLETLKEVWADIMSSSVHAQSTLESVISQWNDYVERKNQLEQWMESVDQKIEHPLQPQPGLKEKFVL
LDHLQSILSEAEDHTRALHRLIAKSRELYEKTEDESFKDTAQEELKTQFNDIMTVAKEKMRKVEEIVKDHLMYLDAVHEFTDWLHSAKEE
LHRWSDMSGDSSATQKKLSKIKELIDSREIGASRLSRVESLAPEVKQNTTASGCELMHTEMQALRADWKQWEDSVFQTQSCLENLVSQMA
LSEQEFSGQVAQLEQALEQFSALLKTWAQQLTLLEGKNTDEEIVECWHKGQEILDALQKAEPRTEDLKSQLNELCRFSRDLSTYSGKVSG
LIKEYNCLCLQASKGCQNKEQILQQRFRKAFRDFQQWLVNAKITTAKCFDIPQNISEVSTSLQKIQEFLSESENGQHKLNMMLSKGELLS
TLLTKEKAKGIQAKVTAAKEDWKNFHSNLHQKESALENLKIQMKDFEVSAEPIQDWLSKTEKMVHESSNRLYDLPAKRREQQKLQSVLEE
IHCYEPQLNRLKEKAQQLWEGQAASKSFRHRVSQLSSQYLALSNLTKEKVSRLDRIVAEHNQFSLGIKELQDWMTDAIHMLDSYCHPTSD
KSVLDSRTLKLEALLSVKQEKEIQMKMIVTRGESVLQNTSPEGIPTIQQQLQSVKDMWASLLSAGIRCKSQLEGALSKWTSYQDGVRQFS
GWMDSMEANLNESERQHAELRDKTTMLGKAKLLNEEVLSYSSLLETIEVKGAGMTEHYVTQLELQDLQERYRAIQERAKEAVTKSEKLVR
LHQEYQRDLKAFEVWLGQEQEKLDQYSVLEGDAHTHETTLRDLQELQVHCAEGQALLNSVLHTREDVIPSGIPQAEDRALESLRQDWQAY
QHRLSETRTQFNNVVNKLRLMEQKFQQVDEWLKTAEEKVSPRTRRQSNRATKEIQLHQMKKWHEEVTAYRDEVEEVGARAQEILDESHVN
SRMGCQATQLTSRYQALLLQVLEQIKFLEEEIQSLEESESSLSSYSDWYGSTHKNFKNVATKIDKVDTVMMGKKLKTLEVLLKDMEKGHS
LLKSAREKGERAVKYLEEGEAERLRKEIHDHMEQLKELTSTVRKEHMTLEKGLHLAKEFSDKCKALTQWIAEYQEILHVPEEPKMELYEK
KAQLSKYKSLQQTVLSHEPSVKSVREKGEALLELVQDVTLKDKIDQLQSDYQDLCSIGKEHVFSLEAKVKDHEDYNSELQEVEKWLLQMS
GRLVAPDLLETSSLETITQQLAHHKAMMEEIAGFEDRLNNLQMKGDTLIGQCADHLQAKLKQNVHAHLQGTKDSYSAICSTAQRMYQSLE
HELQKHVSRQDTLQQCQAWLSAVQPDLEPSPQPPLSRAEAIKQVKHFRALQEQARTYLDLLCSMCDLSNASVKTTAKDIQQTEQTIEQKL
VQAQNLTQGWEEIKHLKSELWIYLQDADQQLQNMKRRHSELELNIAQNMVSQVKDFVKKLQSKQASVNTIIEKVNKLTKKEESPEHKEIN
HLNDQWLDLCRQSNNLCLQREEDLQRTRDYHDCMNVVEVFLEKFTTEWDNLARSDAESTAVHLEALKKLALALQERKYAIEDLKDQKQKM
IEHLNLDDKELVKEQTSHLEQRWFQLEDLIKRKIQVSVTNLEELNVVQSRFQELMEWAEEQQPNIAEALKQSPPPDMAQNLLMDHLAICS
ELEAKQMLLKSLIKDADRVMADLGLNERQVIQKALSDAQSHVNCLSDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREHI
CLLPDDVSKQVKTCKSAQASLKTYQNEVTGLWAQGRELMKEVTEQEKSEVLGKLQELQSVYDSVLQKCSHRLQELEKNLVSRKHFKEDFD
KACHWLKQADIVTFPEINLMNESSELHTQLAKYQNILEQSPEYENLLLTLQRTGQTILPSLNEVDHSYLSEKLNALPRQFNVIVALAKDK
FYKVQEAILARKEYASLIELTTQSLSELEAQFLRMSKVPTDLAVEEALSLQDGCRAILDEVAGLGEAVDELNQKKEGFRSTGQPWQPDKM
LHLVTLYHRLKRQTEQRVSLLEDTTSAYQEHEKMCQQLERQLKSVKEEQSKVNEETLPAEEKLKMYHSLAGSLQDSGIVLKRVTIHLEDL
APHLDPLAYEKARHQIQSWQGELKLLTSAIGETVTECESRMVQSIDFQTEMSRSLDWLRRVKAELSGPVYLDLNLQDIQEEIRKIQIHQE
EVQSSLRIMNALSHKEKEKFTKAKELISADLEHSLAELSELDGDIQEALRTRQATLTEIYSQCQRYYQVFQAANDWLEDAQELLQLAGNG
LDVESAEENLKSHMEFFSTEDQFHSNLEELHSLVATLDPLIKPTGKEDLEQKVASLELRSQRMSRDSGAQVDLLQRCTAQWHDYQKAREE
VIELMNDTEKKLSEFSLLKTSSSHEAEEKLSEHKALVSVVNSFHEKIVALEEKASQLEKTGNDASKATLSRSMTTVWQRWTRLRAVAQDQ
EKILEDAVDEWTGFNNKVKKATEMIDQLQDKLPGSSAEKASKAELLTLLEYHDTFVLELEQQQSALGMLRQQTLSMLQDGAAPTPGEEPP
LMQEITAMQDRCLNMQEKVKTNGKLVKQELKDREMVETQINSVKCWVQETKEYLGNPTIEIDAQLEELQILLTEATNHRQNIEKMAEEQK
EKYLGLYTILPSELSLQLAEVALDLKIRDQIQDKIKEVEQSKATSQELSRQIQKLAKDLTTILTKLKAKTDNVVQAKTDQKVLGEELDGC
NSKLMELDAAVQKFLEQNGQLGKPLAKKIGKLTELHQQTIRQAENRLSKLNQAASHLEEYNEMLELILKWIEKAKVLAHGTIAWNSASQL
REQYILHQTLLEESKEIDSELEAMTEKLQYLTSVYCTEKMSQQVAELGRETEELRQMIKIRLQNLQDAAKDMKKFEAELKKLQAALEQAQ
ATLTSPEVGRLSLKEQLSHRQHLLSEMESLKPKVQAVQLCQSALRIPEDVVASLPLCHAALRLQEEASRLQHTAIQQCNIMQEAVVQYEQ
YEQEMKHLQQLIEGAHREIEDKPVATSNIQELQAQISRHEELAQKIKGYQEQIASLNSKCKMLTMKAKHATMLLTVTEVEGLAEGTEDLD
GELLPTPSAHPSVVMMTAGRCHTLLSPVTEESGEEGTNSEISSPPACRSPSPVANTDASVNQDIAYYQALSAERLQTDAAKIHPSTSASQ
EFYEPGLEPSATAKLGDLQRSWETLKNVISEKQRTLYEALERQQKYQDSLQSISTKMEAIELKLSESPEPGRSPESQMAEHQALMDEILM
LQDEINELQSSLAEELVSESCEADPAEQLALQSTLTVLAERMSTIRMKASGKRQLLEEKLNDQLEEQRQEQALQRYRCEADELDSWLLST
KATLDTALSPPKEPMDMEAQLMDCQNMLVEIEQKVVALSELSVHNENLLLEGKAHTKDEAEQLAGKLRRLKGSLLELQRALHDKQLNMQG
TAQEKEESDVDLTATQSPGVQEWLAQARTTWTQQRQSSLQQQKELEQELAEQKSLLRSVASRGEEILIQHSAAETSGDAGEKPDVLSQEL
GMEGEKSSAEDQMRMKWESLHQEFSTKQKLLQNVLEQEQEQVLYSRPNRLLSGVPLYKGDVPTQDKSAVTSLLDGLNQAFEEVSSQSGGA
KRQSIHLEQKLYDGVSATSTWLDDVEERLFVATALLPEETETCLFNQEILAKDIKEMSEEMDKNKNLFSQAFPENGDNRDVIEDTLGCLL
GRLSLLDSVVNQRCHQMKERLQQILNFQNDLKVLFTSLADNKYIILQKLANVFEQPVAEQIEAIQQAEDGLKEFDAGIIELKRRGDKLQV
EQPSMQELSKLQDMYDELMMIIGSRRSGLNQNLTLKSQYERALQDLADLLETGQEKMAGDQKIIVSSKEEIQQLLDKHKEYFQGLESHMI
LTETLFRKIISFAVQKETQFHTELMAQASAVLKRAHKRGVELEYILETWSHLDEDQQELSRQLEVVESSIPSVGLVEENEDRLIDRITLY
QHLKSSLNEYQPKLYQVLDDGKRLLISISCSDLESQLNQLGECWLSNTNKMSKELHRLETILKHWTRYQSESADLIHWLQSAKDRLEFWT
QQSVTVPQELEMVRDHLNAFLEFSKEVDAQSSLKSSVLSTGNQLLRLKKVDTATLRSELSRIDSQWTDLLTNIPAVQEKLHQLQMDKLPS
RHAISEVMSWISLMENVIQKDEDNIKNSIGYKAIHEYLQKYKGFKIDINCKQLTVDFVNQSVLQISSQDVESKRSDKTDFAEQLGAMNKS
WQILQGLVTEKIQLLEGLLESWSEYENNVQCLKTWFETQEKRLKQQHRIGDQASVQNALKDCQDLEDLIKAKEKEVEKIEQNGLALIQNK
KEDVSSIVMSTLRELGQTWANLDHMVGQLKILLKSVLDQWSSHKVAFDKINSYLMEARYSLSRFRLLTGSLEAVQVQVDNLQNLQDDLEK
QERSLQKFGSITNQLLKECHPPVTETLTNTLKEVNMRWNNLLEEIAEQLQSSKALLQLWQRYKDYSKQCASTVQQQEDRTNELLKAATNK
DIADDEVATWIQDCNDLLKGLGTVKDSLFFLHELGEQLKQQVDASAASAIQSDQLSLSQHLCALEQALCKQQTSLQAGVLDYETFAKSLE
ALEAWIVEAEEILQGQDPSHSSDLSTIQERMEELKGQMLKFSSMAPDLDRLNELGYRLPLNDKEIKRMQNLNRHWSLISSQTTERFSKLQ
SFLLQHQTFLEKCETWMEFLVQTEQKLAVEISGNYQHLLEQQRAHELFQAEMFSRQQILHSIIIDGQRLLEQGQVDDRDEFNLKLTLLSN
QWQGVIRRAQQRRGIIDSQIRQWQRYREMAEKLRKWLVEVSYLPMSGLGSVPIPLQQARTLFDEVQFKEKVFLRQQGSYILTVEAGKQLL
LSADSGAEAALQAELAEIQEKWKSASMRLEEQKKKLAFLLKDWEKCEKGIADSLEKLRTFKKKLSQSLPDHHEELHAEQMRCKELENAVG
SWTDDLTQLSLLKDTLSAYISADDISILNERVELLQRQWEELCHQLSLRRQQIGERLNEWAVFSEKNKELCEWLTQMESKVSQNGDILIE
EMIEKLKKDYQEEIAIAQENKIQLQQMGERLAKASHESKASEIEYKLGKVNDRWQHLLDLIAARVKKLKETLVAVQQLDKNMSSLRTWLA
HIESELAKPIVYDSCNSEEIQRKLNEQQELQRDIEKHSTGVASVLNLCEVLLHDCDACATDAECDSIQQATRNLDRRWRNICAMSMERRL
KIEETWRLWQKFLDDYSRFEDWLKSSERTAAFPSSSGVIYTVAKEELKKFEAFQRQVHECLTQLELINKQYRRLARENRTDSACSLKQMV
HEGNQRWDNLQKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIEHFSECDVQAKIKQLKAFQQEISLNHNKIEQIIAQGEQ
LIEKSEPLDAAIIEEELDELRRYCQEVFGRVERYHKKLIRLPLPDDEHDLSDRELELEDSAALSDLHWHDRSADSLLSPQPSSNLSLSLA
QPLRSERSGRDTPASVDSIPLEWDHDYDLSRDLESAMSRALPSEDEEGQDDKDFYLRGAVGLSGDHSALESQIRQLGKALDDSRFQIQQT
ENIIRSKTPTGPELDTSYKGYMKLLGECSSSIDSVKRLEHKLKEEEESLPGFVNLHSTETQTAGVIDRWELLQAQALSKELRMKQNLQKW
QQFNSDLNSIWAWLGDTEEELEQLQRLELSTDIQTIELQIKKLKELQKAVDHRKAIILSINLCSPEFTQADSKESRDLQDRLSQMNGRWD
RVCSLLEEWRGLLQDALMQCQGFHEMSHGLLLMLENIDRRKNEIVPIDSNLDAEILQDHHKQLMQIKHELLESQLRVASLQDMSCQLLVN
AEGTDCLEAKEKVHVIGNRLKLLLKEVSRHIKELEKLLDVSSSQQDLSSWSSADELDTSGSVSPTSGRSTPNRQKTPRGKCSLSQPGPSV

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for PLXDC2-SYNE1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for PLXDC2-SYNE1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for PLXDC2-SYNE1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneSYNE1C0005586Bipolar Disorder3PSYGENET
TgeneSYNE1C1853116SPINOCEREBELLAR ATAXIA, AUTOSOMAL RECESSIVE 8 (disorder)3CTD_human;GENOMICS_ENGLAND;ORPHANET
TgeneSYNE1C2751807Emery-Dreifuss Muscular Dystrophy 43GENOMICS_ENGLAND;UNIPROT
TgeneSYNE1C0009402Colorectal Carcinoma2CTD_human;UNIPROT
TgeneSYNE1C0009404Colorectal Neoplasms2CTD_human
TgeneSYNE1C0006142Malignant neoplasm of breast1CTD_human
TgeneSYNE1C0007758Cerebellar Ataxia1GENOMICS_ENGLAND
TgeneSYNE1C0013146Drug abuse1CTD_human
TgeneSYNE1C0013170Drug habituation1CTD_human
TgeneSYNE1C0013222Drug Use Disorders1CTD_human
TgeneSYNE1C0029231Organic Mental Disorders, Substance-Induced1CTD_human
TgeneSYNE1C0038580Substance Dependence1CTD_human
TgeneSYNE1C0038586Substance Use Disorders1CTD_human
TgeneSYNE1C0154409Recurrent major depressive episodes1PSYGENET
TgeneSYNE1C0236969Substance-Related Disorders1CTD_human
TgeneSYNE1C0678222Breast Carcinoma1CTD_human
TgeneSYNE1C0740858Substance abuse problem1CTD_human
TgeneSYNE1C1257931Mammary Neoplasms, Human1CTD_human
TgeneSYNE1C1458155Mammary Neoplasms1CTD_human
TgeneSYNE1C1510472Drug Dependence1CTD_human
TgeneSYNE1C2931822Nasopharyngeal carcinoma1CTD_human
TgeneSYNE1C3683483Autosomal Recessive Cerebellar Ataxia Type 11ORPHANET
TgeneSYNE1C3714756Intellectual Disability1GENOMICS_ENGLAND
TgeneSYNE1C4316881Prescription Drug Abuse1CTD_human
TgeneSYNE1C4704874Mammary Carcinoma, Human1CTD_human
TgeneSYNE1C4707155Autosomal recessive myogenic arthrogryposis multiplex congenita1ORPHANET