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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:PPFIA1-RHOD (FusionGDB2 ID:66997)

Fusion Gene Summary for PPFIA1-RHOD

check button Fusion gene summary
Fusion gene informationFusion gene name: PPFIA1-RHOD
Fusion gene ID: 66997
HgeneTgene
Gene symbol

PPFIA1

RHOD

Gene ID

8500

29984

Gene namePTPRF interacting protein alpha 1ras homolog family member D
SynonymsLIP.1|LIP1|LIPRINARHD|RHOHP1|RHOM|Rho
Cytomap

11q13.3

11q13.2

Type of geneprotein-codingprotein-coding
Descriptionliprin-alpha-1LAR-interacting protein 1LIP-1Liprin-alpha1protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1rho-related GTP-binding protein RhoDRho-related protein HP1ras homolog Dras homolog gene family, member Aras homolog gene family, member D
Modification date2020032720200313
UniProtAcc.

GRK7

Ensembl transtripts involved in fusion geneENST00000253925, ENST00000389547, 
ENST00000530548, 		ENST00000308831, 
ENST00000533360, ENST00000532559, 
Fusion gene scores* DoF score44 X 20 X 15=1320010 X 6 X 6=360
# samples 6015
** MAII scorelog2(60/13200*10)=-4.4594316186373
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(15/360*10)=-1.26303440583379
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: PPFIA1 [Title/Abstract] AND RHOD [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointPPFIA1(70118542)-RHOD(66833367), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across PPFIA1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across RHOD (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-EW-A1J3-01APPFIA1chr11

70118542

+RHODchr11

66833367

+
ChimerDB4BRCATCGA-EW-A1J3PPFIA1chr11

70118542

+RHODchr11

66833366

+
ChimerDB4BRCATCGA-EW-A1J3-01APPFIA1chr11

70118542

+RHODchr11

66833367

+
ChimerDB4BRCATCGA-EW-A1J3-01APPFIA1chr11

70118542

-RHODchr11

66833367

+
ChimerDB4BRCATCGA-EW-A1J3-01APPFIA1chr11

70118541

+RHODchr11

66833366

+


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Fusion Gene ORF analysis for PPFIA1-RHOD

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000253925ENST00000308831PPFIA1chr11

70118542

+RHODchr11

66833367

+
In-frameENST00000253925ENST00000533360PPFIA1chr11

70118542

+RHODchr11

66833367

+
5CDS-intronENST00000253925ENST00000532559PPFIA1chr11

70118542

+RHODchr11

66833367

+
In-frameENST00000389547ENST00000308831PPFIA1chr11

70118542

+RHODchr11

66833367

+
In-frameENST00000389547ENST00000533360PPFIA1chr11

70118542

+RHODchr11

66833367

+
5CDS-intronENST00000389547ENST00000532559PPFIA1chr11

70118542

+RHODchr11

66833367

+
intron-3CDSENST00000530548ENST00000308831PPFIA1chr11

70118542

+RHODchr11

66833367

+
intron-3CDSENST00000530548ENST00000533360PPFIA1chr11

70118542

+RHODchr11

66833367

+
intron-intronENST00000530548ENST00000532559PPFIA1chr11

70118542

+RHODchr11

66833367

+
In-frameENST00000253925ENST00000308831PPFIA1chr11

70118542

+RHODchr11

66833366

+
In-frameENST00000253925ENST00000533360PPFIA1chr11

70118542

+RHODchr11

66833366

+
5CDS-intronENST00000253925ENST00000532559PPFIA1chr11

70118542

+RHODchr11

66833366

+
In-frameENST00000389547ENST00000308831PPFIA1chr11

70118542

+RHODchr11

66833366

+
In-frameENST00000389547ENST00000533360PPFIA1chr11

70118542

+RHODchr11

66833366

+
5CDS-intronENST00000389547ENST00000532559PPFIA1chr11

70118542

+RHODchr11

66833366

+
intron-3CDSENST00000530548ENST00000308831PPFIA1chr11

70118542

+RHODchr11

66833366

+
intron-3CDSENST00000530548ENST00000533360PPFIA1chr11

70118542

+RHODchr11

66833366

+
intron-intronENST00000530548ENST00000532559PPFIA1chr11

70118542

+RHODchr11

66833366

+
In-frameENST00000253925ENST00000308831PPFIA1chr11

70118541

+RHODchr11

66833366

+
In-frameENST00000253925ENST00000533360PPFIA1chr11

70118541

+RHODchr11

66833366

+
5CDS-intronENST00000253925ENST00000532559PPFIA1chr11

70118541

+RHODchr11

66833366

+
In-frameENST00000389547ENST00000308831PPFIA1chr11

70118541

+RHODchr11

66833366

+
In-frameENST00000389547ENST00000533360PPFIA1chr11

70118541

+RHODchr11

66833366

+
5CDS-intronENST00000389547ENST00000532559PPFIA1chr11

70118541

+RHODchr11

66833366

+
intron-3CDSENST00000530548ENST00000308831PPFIA1chr11

70118541

+RHODchr11

66833366

+
intron-3CDSENST00000530548ENST00000533360PPFIA1chr11

70118541

+RHODchr11

66833366

+
intron-intronENST00000530548ENST00000532559PPFIA1chr11

70118541

+RHODchr11

66833366

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000253925PPFIA1chr1170118542+ENST00000308831RHODchr1166833367+139147965979304
ENST00000253925PPFIA1chr1170118542+ENST00000533360RHODchr1166833367+90647965703212
ENST00000389547PPFIA1chr1170118542+ENST00000308831RHODchr1166833367+137446248962304
ENST00000389547PPFIA1chr1170118542+ENST00000533360RHODchr1166833367+88946248686212
ENST00000253925PPFIA1chr1170118542+ENST00000308831RHODchr1166833366+139147965979304
ENST00000253925PPFIA1chr1170118542+ENST00000533360RHODchr1166833366+90647965703212
ENST00000389547PPFIA1chr1170118542+ENST00000308831RHODchr1166833366+137446248962304
ENST00000389547PPFIA1chr1170118542+ENST00000533360RHODchr1166833366+88946248686212
ENST00000253925PPFIA1chr1170118541+ENST00000308831RHODchr1166833366+139147965979304
ENST00000253925PPFIA1chr1170118541+ENST00000533360RHODchr1166833366+90647965703212
ENST00000389547PPFIA1chr1170118541+ENST00000308831RHODchr1166833366+137446248962304
ENST00000389547PPFIA1chr1170118541+ENST00000533360RHODchr1166833366+88946248686212

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000253925ENST00000308831PPFIA1chr1170118542+RHODchr1166833367+0.0312789860.96872103
ENST00000253925ENST00000533360PPFIA1chr1170118542+RHODchr1166833367+0.0103285860.98967135
ENST00000389547ENST00000308831PPFIA1chr1170118542+RHODchr1166833367+0.0291160330.9708839
ENST00000389547ENST00000533360PPFIA1chr1170118542+RHODchr1166833367+0.0083670630.99163294
ENST00000253925ENST00000308831PPFIA1chr1170118542+RHODchr1166833366+0.0312789860.96872103
ENST00000253925ENST00000533360PPFIA1chr1170118542+RHODchr1166833366+0.0103285860.98967135
ENST00000389547ENST00000308831PPFIA1chr1170118542+RHODchr1166833366+0.0291160330.9708839
ENST00000389547ENST00000533360PPFIA1chr1170118542+RHODchr1166833366+0.0083670630.99163294
ENST00000253925ENST00000308831PPFIA1chr1170118541+RHODchr1166833366+0.0312789860.96872103
ENST00000253925ENST00000533360PPFIA1chr1170118541+RHODchr1166833366+0.0103285860.98967135
ENST00000389547ENST00000308831PPFIA1chr1170118541+RHODchr1166833366+0.0291160330.9708839
ENST00000389547ENST00000533360PPFIA1chr1170118541+RHODchr1166833366+0.0083670630.99163294

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Fusion Genomic Features for PPFIA1-RHOD


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
PPFIA1chr1170118542+RHODchr1166833366+2.53E-121
PPFIA1chr1170118542+RHODchr1166833366+2.53E-121
PPFIA1chr1170118542+RHODchr1166833366+2.53E-121
PPFIA1chr1170118542+RHODchr1166833366+2.53E-121

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for PPFIA1-RHOD


check button Go to

FGviewer for the breakpoints of chr11:70118542-chr11:66833367

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.RHOD

GRK7

FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.553

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePPFIA1chr11:70118541chr11:66833366ENST00000253925+22817_2588.01597.3333333333333Compositional biasNote=Poly-Gly
HgenePPFIA1chr11:70118541chr11:66833366ENST00000389547+22617_2588.01186.0Compositional biasNote=Poly-Gly
HgenePPFIA1chr11:70118542chr11:66833366ENST00000253925+22817_2588.01597.3333333333333Compositional biasNote=Poly-Gly
HgenePPFIA1chr11:70118542chr11:66833366ENST00000389547+22617_2588.01186.0Compositional biasNote=Poly-Gly
HgenePPFIA1chr11:70118542chr11:66833367ENST00000253925+22817_2588.01597.3333333333333Compositional biasNote=Poly-Gly
HgenePPFIA1chr11:70118542chr11:66833367ENST00000389547+22617_2588.01186.0Compositional biasNote=Poly-Gly
TgeneRHODchr11:70118541chr11:66833366ENST000003088310546_5444.0211.0MotifEffector region
TgeneRHODchr11:70118542chr11:66833366ENST000003088310546_5444.0211.0MotifEffector region
TgeneRHODchr11:70118542chr11:66833367ENST000003088310546_5444.0211.0MotifEffector region
TgeneRHODchr11:70118541chr11:66833366ENST0000030883105129_13244.0211.0Nucleotide bindingGTP
TgeneRHODchr11:70118541chr11:66833366ENST000003088310571_7544.0211.0Nucleotide bindingGTP
TgeneRHODchr11:70118542chr11:66833366ENST0000030883105129_13244.0211.0Nucleotide bindingGTP
TgeneRHODchr11:70118542chr11:66833366ENST000003088310571_7544.0211.0Nucleotide bindingGTP
TgeneRHODchr11:70118542chr11:66833367ENST0000030883105129_13244.0211.0Nucleotide bindingGTP
TgeneRHODchr11:70118542chr11:66833367ENST000003088310571_7544.0211.0Nucleotide bindingGTP

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePPFIA1chr11:70118541chr11:66833366ENST00000253925+2281021_105088.01597.3333333333333Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118541chr11:66833366ENST00000253925+228176_21488.01597.3333333333333Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118541chr11:66833366ENST00000253925+228249_52188.01597.3333333333333Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118541chr11:66833366ENST00000253925+22834_14188.01597.3333333333333Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118541chr11:66833366ENST00000253925+228623_66988.01597.3333333333333Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118541chr11:66833366ENST00000253925+228847_87188.01597.3333333333333Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118541chr11:66833366ENST00000389547+2261021_105088.01186.0Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118541chr11:66833366ENST00000389547+226176_21488.01186.0Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118541chr11:66833366ENST00000389547+226249_52188.01186.0Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118541chr11:66833366ENST00000389547+22634_14188.01186.0Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118541chr11:66833366ENST00000389547+226623_66988.01186.0Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118541chr11:66833366ENST00000389547+226847_87188.01186.0Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:66833366ENST00000253925+2281021_105088.01597.3333333333333Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:66833366ENST00000253925+228176_21488.01597.3333333333333Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:66833366ENST00000253925+228249_52188.01597.3333333333333Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:66833366ENST00000253925+22834_14188.01597.3333333333333Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:66833366ENST00000253925+228623_66988.01597.3333333333333Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:66833366ENST00000253925+228847_87188.01597.3333333333333Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:66833366ENST00000389547+2261021_105088.01186.0Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:66833366ENST00000389547+226176_21488.01186.0Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:66833366ENST00000389547+226249_52188.01186.0Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:66833366ENST00000389547+22634_14188.01186.0Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:66833366ENST00000389547+226623_66988.01186.0Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:66833366ENST00000389547+226847_87188.01186.0Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:66833367ENST00000253925+2281021_105088.01597.3333333333333Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:66833367ENST00000253925+228176_21488.01597.3333333333333Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:66833367ENST00000253925+228249_52188.01597.3333333333333Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:66833367ENST00000253925+22834_14188.01597.3333333333333Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:66833367ENST00000253925+228623_66988.01597.3333333333333Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:66833367ENST00000253925+228847_87188.01597.3333333333333Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:66833367ENST00000389547+2261021_105088.01186.0Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:66833367ENST00000389547+226176_21488.01186.0Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:66833367ENST00000389547+226249_52188.01186.0Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:66833367ENST00000389547+22634_14188.01186.0Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:66833367ENST00000389547+226623_66988.01186.0Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:66833367ENST00000389547+226847_87188.01186.0Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118541chr11:66833366ENST00000253925+2281051_112088.01597.3333333333333DomainSAM 3
HgenePPFIA1chr11:70118541chr11:66833366ENST00000253925+228878_94488.01597.3333333333333DomainSAM 1
HgenePPFIA1chr11:70118541chr11:66833366ENST00000253925+228963_102788.01597.3333333333333DomainSAM 2
HgenePPFIA1chr11:70118541chr11:66833366ENST00000389547+2261051_112088.01186.0DomainSAM 3
HgenePPFIA1chr11:70118541chr11:66833366ENST00000389547+226878_94488.01186.0DomainSAM 1
HgenePPFIA1chr11:70118541chr11:66833366ENST00000389547+226963_102788.01186.0DomainSAM 2
HgenePPFIA1chr11:70118542chr11:66833366ENST00000253925+2281051_112088.01597.3333333333333DomainSAM 3
HgenePPFIA1chr11:70118542chr11:66833366ENST00000253925+228878_94488.01597.3333333333333DomainSAM 1
HgenePPFIA1chr11:70118542chr11:66833366ENST00000253925+228963_102788.01597.3333333333333DomainSAM 2
HgenePPFIA1chr11:70118542chr11:66833366ENST00000389547+2261051_112088.01186.0DomainSAM 3
HgenePPFIA1chr11:70118542chr11:66833366ENST00000389547+226878_94488.01186.0DomainSAM 1
HgenePPFIA1chr11:70118542chr11:66833366ENST00000389547+226963_102788.01186.0DomainSAM 2
HgenePPFIA1chr11:70118542chr11:66833367ENST00000253925+2281051_112088.01597.3333333333333DomainSAM 3
HgenePPFIA1chr11:70118542chr11:66833367ENST00000253925+228878_94488.01597.3333333333333DomainSAM 1
HgenePPFIA1chr11:70118542chr11:66833367ENST00000253925+228963_102788.01597.3333333333333DomainSAM 2
HgenePPFIA1chr11:70118542chr11:66833367ENST00000389547+2261051_112088.01186.0DomainSAM 3
HgenePPFIA1chr11:70118542chr11:66833367ENST00000389547+226878_94488.01186.0DomainSAM 1
HgenePPFIA1chr11:70118542chr11:66833367ENST00000389547+226963_102788.01186.0DomainSAM 2
TgeneRHODchr11:70118541chr11:66833366ENST000003088310524_3144.0211.0Nucleotide bindingGTP
TgeneRHODchr11:70118542chr11:66833366ENST000003088310524_3144.0211.0Nucleotide bindingGTP
TgeneRHODchr11:70118542chr11:66833367ENST000003088310524_3144.0211.0Nucleotide bindingGTP


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Fusion Gene Sequence for PPFIA1-RHOD


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000253925_ENST00000308831_TCGA-EW-A1J3-01A_PPFIA1_chr11_70118542_+_RHOD_chr11_66833367_length(transcript)=1391nt_BP=479nt
GCCGCGCAGCCGGGCCCGCTCCTCCTCCGCTCCGCCAGTGTCCGGCCGCGGGCCGGCCTTAGTGACTGGGGCGGCGGGCCCCGGGGCCGC
GGCGTGGGGCGGGCAGGCGGACGCCGGCCGCGGGCTGCTTTCGTCGGCTCCCAAGCTCTCCCGGAGCGAGCAGCCGCCCGCGAGCCGCCG
CGGAGCCTCCTCGCCCGCTCCCGCCGGCGAGCAAGATGATGTGCGAGGTGATGCCGACCATCAGCGAAGCAGAAGGCCCCCCTGGAGGAG
GTGGAGGCCATGGTTCCGGCTCCCCTTCACAGCCAGATGCAGATTCACATTTTGAACAGTTGATGGTCTCCATGCTAGAAGAAAGGGACC
GCCTTCTTGATACACTGAGAGAGACTCAAGAAACGCTGGCCTTAACCCAGGGGAAGTTACACGAGGTTGGTCATGAAAGAGATTCCTTGC
AGAGACAGCTCAACACGGCACTTCCACAGAGCTACACCCCCACGGTGTTTGAGCGGTACATGGTCAACCTGCAAGTGAAAGGCAAACCTG
TGCACCTCCACATCTGGGACACAGCAGGGCAAGATGACTATGACCGCCTGCGGCCCCTGTTCTACCCTGACGCCAGCGTCCTGCTGCTTT
GCTTCGATGTCACCAGCCCGAACAGCTTTGACAACATCTTTAACCGGTGGTACCCAGAAGTGAATCATTTCTGCAAGAAGGTACCCATCA
TCGTCGTGGGCTGCAAGACTGACCTGTGCAAGGACAAATCACTGGTGAACAAGCTCCGAAGAAACGGATTGGAGCCTGTGACCTACCACA
GGGGCCAGGAGATGGCGAGGTCCGTGGGCGCGGTGGCCTACCTCGAGTGCTCGGCTCGGCTCCATGACAACGTCCACGCCGTCTTCCAGG
AGGCCGCCGAGGTGGCCCTCAGCAGCCGCGGTCGCAACTTCTGGCGGCGGATTACCCAGGGCTTTTGCGTGGTGACCTGAGCGGCTCGGG
GCGTCCCAGCGACGCGGGAAGGGGCAGGGCGCTGACCTGCTGCTGAGCTGGCTGGGCTGGACCCGGTCCCTAGGCTGTGACCGCCGAACT
CCACTGCAACAGACGGGCGCCACCAAAGCCAGGCCCTGAGGCCTGGGAGTCCTGGACTGAGAAAGGGGGTTCCTGGGCCCACCTGCTCTG
TGTAGGGCTCGTCCTGCGGTGCCCGAGAATCACTCGCTAACCCCTATGCCCGGTCCCGGACCGACATCCTGGAGCCGCCTGTGCAGCCTG
ATGCCCCCTCGTGGCTGCTCCCAGGGCTGCACCTGCCAGGACCTAATGTTCTTAGGTCCCTCTGGCCAGAACCCACACCCGGCCCCTTCC

>In-frame_ENST00000253925_ENST00000308831_TCGA-EW-A1J3-01A_PPFIA1_chr11_70118542_+_RHOD_chr11_66833367_length(amino acids)=304AA_start in transcript=65_stop in transcript=979
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQSYTPTVFERYMVNLQVKGKPVHLHIWDTAGQDDYDRLRPLFY
PDASVLLLCFDVTSPNSFDNIFNRWYPEVNHFCKKVPIIVVGCKTDLCKDKSLVNKLRRNGLEPVTYHRGQEMARSVGAVAYLECSARLH

--------------------------------------------------------------
>In-frame_ENST00000253925_ENST00000533360_TCGA-EW-A1J3-01A_PPFIA1_chr11_70118542_+_RHOD_chr11_66833367_length(transcript)=906nt_BP=479nt
GCCGCGCAGCCGGGCCCGCTCCTCCTCCGCTCCGCCAGTGTCCGGCCGCGGGCCGGCCTTAGTGACTGGGGCGGCGGGCCCCGGGGCCGC
GGCGTGGGGCGGGCAGGCGGACGCCGGCCGCGGGCTGCTTTCGTCGGCTCCCAAGCTCTCCCGGAGCGAGCAGCCGCCCGCGAGCCGCCG
CGGAGCCTCCTCGCCCGCTCCCGCCGGCGAGCAAGATGATGTGCGAGGTGATGCCGACCATCAGCGAAGCAGAAGGCCCCCCTGGAGGAG
GTGGAGGCCATGGTTCCGGCTCCCCTTCACAGCCAGATGCAGATTCACATTTTGAACAGTTGATGGTCTCCATGCTAGAAGAAAGGGACC
GCCTTCTTGATACACTGAGAGAGACTCAAGAAACGCTGGCCTTAACCCAGGGGAAGTTACACGAGGTTGGTCATGAAAGAGATTCCTTGC
AGAGACAGCTCAACACGGCACTTCCACAGAGCTACACCCCCACGGTGTTTGAGCGGTACATGGTCAACCTGCAAGTGAAAGGCAAACCTG
TGCACCTCCACATCTGGGACACAGCAGGGCAAGATGACTATGACCGCCTGCGGCCCCTGTTCTACCCTGACGCCAGCGTCCTGCTGCTTT
GCTTCGATGTCACCAGCCCGAACAGCTTTGACAACATCTTTAACCGGTTTCTCCCTAGGTGCTGGCTTTGCTGATTATCCATATCAGAGC
TCAGGCTGGGGAGCAAGAGAGTGGTCCACTGAGAGGGCCAGAACTCTCCAGGGCTCACACATGCCCCCCACATGCCCCCTCGCCCCCCTG
CAGTGGTACCCAGAAGTGAATCATTTCTGCAAGAAGGTACCCATCATCGTCGTGGGCTGCAAGACTGACCTGTGCAAGGACAAATCACTG

>In-frame_ENST00000253925_ENST00000533360_TCGA-EW-A1J3-01A_PPFIA1_chr11_70118542_+_RHOD_chr11_66833367_length(amino acids)=212AA_start in transcript=65_stop in transcript=703
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQSYTPTVFERYMVNLQVKGKPVHLHIWDTAGQDDYDRLRPLFY

--------------------------------------------------------------
>In-frame_ENST00000389547_ENST00000308831_TCGA-EW-A1J3-01A_PPFIA1_chr11_70118542_+_RHOD_chr11_66833367_length(transcript)=1374nt_BP=462nt
GCTCCTCCTCCGCTCCGCCAGTGTCCGGCCGCGGGCCGGCCTTAGTGACTGGGGCGGCGGGCCCCGGGGCCGCGGCGTGGGGCGGGCAGG
CGGACGCCGGCCGCGGGCTGCTTTCGTCGGCTCCCAAGCTCTCCCGGAGCGAGCAGCCGCCCGCGAGCCGCCGCGGAGCCTCCTCGCCCG
CTCCCGCCGGCGAGCAAGATGATGTGCGAGGTGATGCCGACCATCAGCGAAGCAGAAGGCCCCCCTGGAGGAGGTGGAGGCCATGGTTCC
GGCTCCCCTTCACAGCCAGATGCAGATTCACATTTTGAACAGTTGATGGTCTCCATGCTAGAAGAAAGGGACCGCCTTCTTGATACACTG
AGAGAGACTCAAGAAACGCTGGCCTTAACCCAGGGGAAGTTACACGAGGTTGGTCATGAAAGAGATTCCTTGCAGAGACAGCTCAACACG
GCACTTCCACAGAGCTACACCCCCACGGTGTTTGAGCGGTACATGGTCAACCTGCAAGTGAAAGGCAAACCTGTGCACCTCCACATCTGG
GACACAGCAGGGCAAGATGACTATGACCGCCTGCGGCCCCTGTTCTACCCTGACGCCAGCGTCCTGCTGCTTTGCTTCGATGTCACCAGC
CCGAACAGCTTTGACAACATCTTTAACCGGTGGTACCCAGAAGTGAATCATTTCTGCAAGAAGGTACCCATCATCGTCGTGGGCTGCAAG
ACTGACCTGTGCAAGGACAAATCACTGGTGAACAAGCTCCGAAGAAACGGATTGGAGCCTGTGACCTACCACAGGGGCCAGGAGATGGCG
AGGTCCGTGGGCGCGGTGGCCTACCTCGAGTGCTCGGCTCGGCTCCATGACAACGTCCACGCCGTCTTCCAGGAGGCCGCCGAGGTGGCC
CTCAGCAGCCGCGGTCGCAACTTCTGGCGGCGGATTACCCAGGGCTTTTGCGTGGTGACCTGAGCGGCTCGGGGCGTCCCAGCGACGCGG
GAAGGGGCAGGGCGCTGACCTGCTGCTGAGCTGGCTGGGCTGGACCCGGTCCCTAGGCTGTGACCGCCGAACTCCACTGCAACAGACGGG
CGCCACCAAAGCCAGGCCCTGAGGCCTGGGAGTCCTGGACTGAGAAAGGGGGTTCCTGGGCCCACCTGCTCTGTGTAGGGCTCGTCCTGC
GGTGCCCGAGAATCACTCGCTAACCCCTATGCCCGGTCCCGGACCGACATCCTGGAGCCGCCTGTGCAGCCTGATGCCCCCTCGTGGCTG
CTCCCAGGGCTGCACCTGCCAGGACCTAATGTTCTTAGGTCCCTCTGGCCAGAACCCACACCCGGCCCCTTCCCACCTGTCATACTGGTA

>In-frame_ENST00000389547_ENST00000308831_TCGA-EW-A1J3-01A_PPFIA1_chr11_70118542_+_RHOD_chr11_66833367_length(amino acids)=304AA_start in transcript=48_stop in transcript=962
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQSYTPTVFERYMVNLQVKGKPVHLHIWDTAGQDDYDRLRPLFY
PDASVLLLCFDVTSPNSFDNIFNRWYPEVNHFCKKVPIIVVGCKTDLCKDKSLVNKLRRNGLEPVTYHRGQEMARSVGAVAYLECSARLH

--------------------------------------------------------------
>In-frame_ENST00000389547_ENST00000533360_TCGA-EW-A1J3-01A_PPFIA1_chr11_70118542_+_RHOD_chr11_66833367_length(transcript)=889nt_BP=462nt
GCTCCTCCTCCGCTCCGCCAGTGTCCGGCCGCGGGCCGGCCTTAGTGACTGGGGCGGCGGGCCCCGGGGCCGCGGCGTGGGGCGGGCAGG
CGGACGCCGGCCGCGGGCTGCTTTCGTCGGCTCCCAAGCTCTCCCGGAGCGAGCAGCCGCCCGCGAGCCGCCGCGGAGCCTCCTCGCCCG
CTCCCGCCGGCGAGCAAGATGATGTGCGAGGTGATGCCGACCATCAGCGAAGCAGAAGGCCCCCCTGGAGGAGGTGGAGGCCATGGTTCC
GGCTCCCCTTCACAGCCAGATGCAGATTCACATTTTGAACAGTTGATGGTCTCCATGCTAGAAGAAAGGGACCGCCTTCTTGATACACTG
AGAGAGACTCAAGAAACGCTGGCCTTAACCCAGGGGAAGTTACACGAGGTTGGTCATGAAAGAGATTCCTTGCAGAGACAGCTCAACACG
GCACTTCCACAGAGCTACACCCCCACGGTGTTTGAGCGGTACATGGTCAACCTGCAAGTGAAAGGCAAACCTGTGCACCTCCACATCTGG
GACACAGCAGGGCAAGATGACTATGACCGCCTGCGGCCCCTGTTCTACCCTGACGCCAGCGTCCTGCTGCTTTGCTTCGATGTCACCAGC
CCGAACAGCTTTGACAACATCTTTAACCGGTTTCTCCCTAGGTGCTGGCTTTGCTGATTATCCATATCAGAGCTCAGGCTGGGGAGCAAG
AGAGTGGTCCACTGAGAGGGCCAGAACTCTCCAGGGCTCACACATGCCCCCCACATGCCCCCTCGCCCCCCTGCAGTGGTACCCAGAAGT

>In-frame_ENST00000389547_ENST00000533360_TCGA-EW-A1J3-01A_PPFIA1_chr11_70118542_+_RHOD_chr11_66833367_length(amino acids)=212AA_start in transcript=48_stop in transcript=686
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQSYTPTVFERYMVNLQVKGKPVHLHIWDTAGQDDYDRLRPLFY

--------------------------------------------------------------
>In-frame_ENST00000253925_ENST00000308831_TCGA-EW-A1J3_PPFIA1_chr11_70118542_+_RHOD_chr11_66833366_length(transcript)=1391nt_BP=479nt
GCCGCGCAGCCGGGCCCGCTCCTCCTCCGCTCCGCCAGTGTCCGGCCGCGGGCCGGCCTTAGTGACTGGGGCGGCGGGCCCCGGGGCCGC
GGCGTGGGGCGGGCAGGCGGACGCCGGCCGCGGGCTGCTTTCGTCGGCTCCCAAGCTCTCCCGGAGCGAGCAGCCGCCCGCGAGCCGCCG
CGGAGCCTCCTCGCCCGCTCCCGCCGGCGAGCAAGATGATGTGCGAGGTGATGCCGACCATCAGCGAAGCAGAAGGCCCCCCTGGAGGAG
GTGGAGGCCATGGTTCCGGCTCCCCTTCACAGCCAGATGCAGATTCACATTTTGAACAGTTGATGGTCTCCATGCTAGAAGAAAGGGACC
GCCTTCTTGATACACTGAGAGAGACTCAAGAAACGCTGGCCTTAACCCAGGGGAAGTTACACGAGGTTGGTCATGAAAGAGATTCCTTGC
AGAGACAGCTCAACACGGCACTTCCACAGAGCTACACCCCCACGGTGTTTGAGCGGTACATGGTCAACCTGCAAGTGAAAGGCAAACCTG
TGCACCTCCACATCTGGGACACAGCAGGGCAAGATGACTATGACCGCCTGCGGCCCCTGTTCTACCCTGACGCCAGCGTCCTGCTGCTTT
GCTTCGATGTCACCAGCCCGAACAGCTTTGACAACATCTTTAACCGGTGGTACCCAGAAGTGAATCATTTCTGCAAGAAGGTACCCATCA
TCGTCGTGGGCTGCAAGACTGACCTGTGCAAGGACAAATCACTGGTGAACAAGCTCCGAAGAAACGGATTGGAGCCTGTGACCTACCACA
GGGGCCAGGAGATGGCGAGGTCCGTGGGCGCGGTGGCCTACCTCGAGTGCTCGGCTCGGCTCCATGACAACGTCCACGCCGTCTTCCAGG
AGGCCGCCGAGGTGGCCCTCAGCAGCCGCGGTCGCAACTTCTGGCGGCGGATTACCCAGGGCTTTTGCGTGGTGACCTGAGCGGCTCGGG
GCGTCCCAGCGACGCGGGAAGGGGCAGGGCGCTGACCTGCTGCTGAGCTGGCTGGGCTGGACCCGGTCCCTAGGCTGTGACCGCCGAACT
CCACTGCAACAGACGGGCGCCACCAAAGCCAGGCCCTGAGGCCTGGGAGTCCTGGACTGAGAAAGGGGGTTCCTGGGCCCACCTGCTCTG
TGTAGGGCTCGTCCTGCGGTGCCCGAGAATCACTCGCTAACCCCTATGCCCGGTCCCGGACCGACATCCTGGAGCCGCCTGTGCAGCCTG
ATGCCCCCTCGTGGCTGCTCCCAGGGCTGCACCTGCCAGGACCTAATGTTCTTAGGTCCCTCTGGCCAGAACCCACACCCGGCCCCTTCC

>In-frame_ENST00000253925_ENST00000308831_TCGA-EW-A1J3_PPFIA1_chr11_70118542_+_RHOD_chr11_66833366_length(amino acids)=304AA_start in transcript=65_stop in transcript=979
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQSYTPTVFERYMVNLQVKGKPVHLHIWDTAGQDDYDRLRPLFY
PDASVLLLCFDVTSPNSFDNIFNRWYPEVNHFCKKVPIIVVGCKTDLCKDKSLVNKLRRNGLEPVTYHRGQEMARSVGAVAYLECSARLH

--------------------------------------------------------------
>In-frame_ENST00000253925_ENST00000533360_TCGA-EW-A1J3_PPFIA1_chr11_70118542_+_RHOD_chr11_66833366_length(transcript)=906nt_BP=479nt
GCCGCGCAGCCGGGCCCGCTCCTCCTCCGCTCCGCCAGTGTCCGGCCGCGGGCCGGCCTTAGTGACTGGGGCGGCGGGCCCCGGGGCCGC
GGCGTGGGGCGGGCAGGCGGACGCCGGCCGCGGGCTGCTTTCGTCGGCTCCCAAGCTCTCCCGGAGCGAGCAGCCGCCCGCGAGCCGCCG
CGGAGCCTCCTCGCCCGCTCCCGCCGGCGAGCAAGATGATGTGCGAGGTGATGCCGACCATCAGCGAAGCAGAAGGCCCCCCTGGAGGAG
GTGGAGGCCATGGTTCCGGCTCCCCTTCACAGCCAGATGCAGATTCACATTTTGAACAGTTGATGGTCTCCATGCTAGAAGAAAGGGACC
GCCTTCTTGATACACTGAGAGAGACTCAAGAAACGCTGGCCTTAACCCAGGGGAAGTTACACGAGGTTGGTCATGAAAGAGATTCCTTGC
AGAGACAGCTCAACACGGCACTTCCACAGAGCTACACCCCCACGGTGTTTGAGCGGTACATGGTCAACCTGCAAGTGAAAGGCAAACCTG
TGCACCTCCACATCTGGGACACAGCAGGGCAAGATGACTATGACCGCCTGCGGCCCCTGTTCTACCCTGACGCCAGCGTCCTGCTGCTTT
GCTTCGATGTCACCAGCCCGAACAGCTTTGACAACATCTTTAACCGGTTTCTCCCTAGGTGCTGGCTTTGCTGATTATCCATATCAGAGC
TCAGGCTGGGGAGCAAGAGAGTGGTCCACTGAGAGGGCCAGAACTCTCCAGGGCTCACACATGCCCCCCACATGCCCCCTCGCCCCCCTG
CAGTGGTACCCAGAAGTGAATCATTTCTGCAAGAAGGTACCCATCATCGTCGTGGGCTGCAAGACTGACCTGTGCAAGGACAAATCACTG

>In-frame_ENST00000253925_ENST00000533360_TCGA-EW-A1J3_PPFIA1_chr11_70118542_+_RHOD_chr11_66833366_length(amino acids)=212AA_start in transcript=65_stop in transcript=703
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQSYTPTVFERYMVNLQVKGKPVHLHIWDTAGQDDYDRLRPLFY

--------------------------------------------------------------
>In-frame_ENST00000389547_ENST00000308831_TCGA-EW-A1J3_PPFIA1_chr11_70118542_+_RHOD_chr11_66833366_length(transcript)=1374nt_BP=462nt
GCTCCTCCTCCGCTCCGCCAGTGTCCGGCCGCGGGCCGGCCTTAGTGACTGGGGCGGCGGGCCCCGGGGCCGCGGCGTGGGGCGGGCAGG
CGGACGCCGGCCGCGGGCTGCTTTCGTCGGCTCCCAAGCTCTCCCGGAGCGAGCAGCCGCCCGCGAGCCGCCGCGGAGCCTCCTCGCCCG
CTCCCGCCGGCGAGCAAGATGATGTGCGAGGTGATGCCGACCATCAGCGAAGCAGAAGGCCCCCCTGGAGGAGGTGGAGGCCATGGTTCC
GGCTCCCCTTCACAGCCAGATGCAGATTCACATTTTGAACAGTTGATGGTCTCCATGCTAGAAGAAAGGGACCGCCTTCTTGATACACTG
AGAGAGACTCAAGAAACGCTGGCCTTAACCCAGGGGAAGTTACACGAGGTTGGTCATGAAAGAGATTCCTTGCAGAGACAGCTCAACACG
GCACTTCCACAGAGCTACACCCCCACGGTGTTTGAGCGGTACATGGTCAACCTGCAAGTGAAAGGCAAACCTGTGCACCTCCACATCTGG
GACACAGCAGGGCAAGATGACTATGACCGCCTGCGGCCCCTGTTCTACCCTGACGCCAGCGTCCTGCTGCTTTGCTTCGATGTCACCAGC
CCGAACAGCTTTGACAACATCTTTAACCGGTGGTACCCAGAAGTGAATCATTTCTGCAAGAAGGTACCCATCATCGTCGTGGGCTGCAAG
ACTGACCTGTGCAAGGACAAATCACTGGTGAACAAGCTCCGAAGAAACGGATTGGAGCCTGTGACCTACCACAGGGGCCAGGAGATGGCG
AGGTCCGTGGGCGCGGTGGCCTACCTCGAGTGCTCGGCTCGGCTCCATGACAACGTCCACGCCGTCTTCCAGGAGGCCGCCGAGGTGGCC
CTCAGCAGCCGCGGTCGCAACTTCTGGCGGCGGATTACCCAGGGCTTTTGCGTGGTGACCTGAGCGGCTCGGGGCGTCCCAGCGACGCGG
GAAGGGGCAGGGCGCTGACCTGCTGCTGAGCTGGCTGGGCTGGACCCGGTCCCTAGGCTGTGACCGCCGAACTCCACTGCAACAGACGGG
CGCCACCAAAGCCAGGCCCTGAGGCCTGGGAGTCCTGGACTGAGAAAGGGGGTTCCTGGGCCCACCTGCTCTGTGTAGGGCTCGTCCTGC
GGTGCCCGAGAATCACTCGCTAACCCCTATGCCCGGTCCCGGACCGACATCCTGGAGCCGCCTGTGCAGCCTGATGCCCCCTCGTGGCTG
CTCCCAGGGCTGCACCTGCCAGGACCTAATGTTCTTAGGTCCCTCTGGCCAGAACCCACACCCGGCCCCTTCCCACCTGTCATACTGGTA

>In-frame_ENST00000389547_ENST00000308831_TCGA-EW-A1J3_PPFIA1_chr11_70118542_+_RHOD_chr11_66833366_length(amino acids)=304AA_start in transcript=48_stop in transcript=962
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQSYTPTVFERYMVNLQVKGKPVHLHIWDTAGQDDYDRLRPLFY
PDASVLLLCFDVTSPNSFDNIFNRWYPEVNHFCKKVPIIVVGCKTDLCKDKSLVNKLRRNGLEPVTYHRGQEMARSVGAVAYLECSARLH

--------------------------------------------------------------
>In-frame_ENST00000389547_ENST00000533360_TCGA-EW-A1J3_PPFIA1_chr11_70118542_+_RHOD_chr11_66833366_length(transcript)=889nt_BP=462nt
GCTCCTCCTCCGCTCCGCCAGTGTCCGGCCGCGGGCCGGCCTTAGTGACTGGGGCGGCGGGCCCCGGGGCCGCGGCGTGGGGCGGGCAGG
CGGACGCCGGCCGCGGGCTGCTTTCGTCGGCTCCCAAGCTCTCCCGGAGCGAGCAGCCGCCCGCGAGCCGCCGCGGAGCCTCCTCGCCCG
CTCCCGCCGGCGAGCAAGATGATGTGCGAGGTGATGCCGACCATCAGCGAAGCAGAAGGCCCCCCTGGAGGAGGTGGAGGCCATGGTTCC
GGCTCCCCTTCACAGCCAGATGCAGATTCACATTTTGAACAGTTGATGGTCTCCATGCTAGAAGAAAGGGACCGCCTTCTTGATACACTG
AGAGAGACTCAAGAAACGCTGGCCTTAACCCAGGGGAAGTTACACGAGGTTGGTCATGAAAGAGATTCCTTGCAGAGACAGCTCAACACG
GCACTTCCACAGAGCTACACCCCCACGGTGTTTGAGCGGTACATGGTCAACCTGCAAGTGAAAGGCAAACCTGTGCACCTCCACATCTGG
GACACAGCAGGGCAAGATGACTATGACCGCCTGCGGCCCCTGTTCTACCCTGACGCCAGCGTCCTGCTGCTTTGCTTCGATGTCACCAGC
CCGAACAGCTTTGACAACATCTTTAACCGGTTTCTCCCTAGGTGCTGGCTTTGCTGATTATCCATATCAGAGCTCAGGCTGGGGAGCAAG
AGAGTGGTCCACTGAGAGGGCCAGAACTCTCCAGGGCTCACACATGCCCCCCACATGCCCCCTCGCCCCCCTGCAGTGGTACCCAGAAGT

>In-frame_ENST00000389547_ENST00000533360_TCGA-EW-A1J3_PPFIA1_chr11_70118542_+_RHOD_chr11_66833366_length(amino acids)=212AA_start in transcript=48_stop in transcript=686
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQSYTPTVFERYMVNLQVKGKPVHLHIWDTAGQDDYDRLRPLFY

--------------------------------------------------------------
>In-frame_ENST00000253925_ENST00000308831_TCGA-EW-A1J3-01A_PPFIA1_chr11_70118541_+_RHOD_chr11_66833366_length(transcript)=1391nt_BP=479nt
GCCGCGCAGCCGGGCCCGCTCCTCCTCCGCTCCGCCAGTGTCCGGCCGCGGGCCGGCCTTAGTGACTGGGGCGGCGGGCCCCGGGGCCGC
GGCGTGGGGCGGGCAGGCGGACGCCGGCCGCGGGCTGCTTTCGTCGGCTCCCAAGCTCTCCCGGAGCGAGCAGCCGCCCGCGAGCCGCCG
CGGAGCCTCCTCGCCCGCTCCCGCCGGCGAGCAAGATGATGTGCGAGGTGATGCCGACCATCAGCGAAGCAGAAGGCCCCCCTGGAGGAG
GTGGAGGCCATGGTTCCGGCTCCCCTTCACAGCCAGATGCAGATTCACATTTTGAACAGTTGATGGTCTCCATGCTAGAAGAAAGGGACC
GCCTTCTTGATACACTGAGAGAGACTCAAGAAACGCTGGCCTTAACCCAGGGGAAGTTACACGAGGTTGGTCATGAAAGAGATTCCTTGC
AGAGACAGCTCAACACGGCACTTCCACAGAGCTACACCCCCACGGTGTTTGAGCGGTACATGGTCAACCTGCAAGTGAAAGGCAAACCTG
TGCACCTCCACATCTGGGACACAGCAGGGCAAGATGACTATGACCGCCTGCGGCCCCTGTTCTACCCTGACGCCAGCGTCCTGCTGCTTT
GCTTCGATGTCACCAGCCCGAACAGCTTTGACAACATCTTTAACCGGTGGTACCCAGAAGTGAATCATTTCTGCAAGAAGGTACCCATCA
TCGTCGTGGGCTGCAAGACTGACCTGTGCAAGGACAAATCACTGGTGAACAAGCTCCGAAGAAACGGATTGGAGCCTGTGACCTACCACA
GGGGCCAGGAGATGGCGAGGTCCGTGGGCGCGGTGGCCTACCTCGAGTGCTCGGCTCGGCTCCATGACAACGTCCACGCCGTCTTCCAGG
AGGCCGCCGAGGTGGCCCTCAGCAGCCGCGGTCGCAACTTCTGGCGGCGGATTACCCAGGGCTTTTGCGTGGTGACCTGAGCGGCTCGGG
GCGTCCCAGCGACGCGGGAAGGGGCAGGGCGCTGACCTGCTGCTGAGCTGGCTGGGCTGGACCCGGTCCCTAGGCTGTGACCGCCGAACT
CCACTGCAACAGACGGGCGCCACCAAAGCCAGGCCCTGAGGCCTGGGAGTCCTGGACTGAGAAAGGGGGTTCCTGGGCCCACCTGCTCTG
TGTAGGGCTCGTCCTGCGGTGCCCGAGAATCACTCGCTAACCCCTATGCCCGGTCCCGGACCGACATCCTGGAGCCGCCTGTGCAGCCTG
ATGCCCCCTCGTGGCTGCTCCCAGGGCTGCACCTGCCAGGACCTAATGTTCTTAGGTCCCTCTGGCCAGAACCCACACCCGGCCCCTTCC

>In-frame_ENST00000253925_ENST00000308831_TCGA-EW-A1J3-01A_PPFIA1_chr11_70118541_+_RHOD_chr11_66833366_length(amino acids)=304AA_start in transcript=65_stop in transcript=979
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQSYTPTVFERYMVNLQVKGKPVHLHIWDTAGQDDYDRLRPLFY
PDASVLLLCFDVTSPNSFDNIFNRWYPEVNHFCKKVPIIVVGCKTDLCKDKSLVNKLRRNGLEPVTYHRGQEMARSVGAVAYLECSARLH

--------------------------------------------------------------
>In-frame_ENST00000253925_ENST00000533360_TCGA-EW-A1J3-01A_PPFIA1_chr11_70118541_+_RHOD_chr11_66833366_length(transcript)=906nt_BP=479nt
GCCGCGCAGCCGGGCCCGCTCCTCCTCCGCTCCGCCAGTGTCCGGCCGCGGGCCGGCCTTAGTGACTGGGGCGGCGGGCCCCGGGGCCGC
GGCGTGGGGCGGGCAGGCGGACGCCGGCCGCGGGCTGCTTTCGTCGGCTCCCAAGCTCTCCCGGAGCGAGCAGCCGCCCGCGAGCCGCCG
CGGAGCCTCCTCGCCCGCTCCCGCCGGCGAGCAAGATGATGTGCGAGGTGATGCCGACCATCAGCGAAGCAGAAGGCCCCCCTGGAGGAG
GTGGAGGCCATGGTTCCGGCTCCCCTTCACAGCCAGATGCAGATTCACATTTTGAACAGTTGATGGTCTCCATGCTAGAAGAAAGGGACC
GCCTTCTTGATACACTGAGAGAGACTCAAGAAACGCTGGCCTTAACCCAGGGGAAGTTACACGAGGTTGGTCATGAAAGAGATTCCTTGC
AGAGACAGCTCAACACGGCACTTCCACAGAGCTACACCCCCACGGTGTTTGAGCGGTACATGGTCAACCTGCAAGTGAAAGGCAAACCTG
TGCACCTCCACATCTGGGACACAGCAGGGCAAGATGACTATGACCGCCTGCGGCCCCTGTTCTACCCTGACGCCAGCGTCCTGCTGCTTT
GCTTCGATGTCACCAGCCCGAACAGCTTTGACAACATCTTTAACCGGTTTCTCCCTAGGTGCTGGCTTTGCTGATTATCCATATCAGAGC
TCAGGCTGGGGAGCAAGAGAGTGGTCCACTGAGAGGGCCAGAACTCTCCAGGGCTCACACATGCCCCCCACATGCCCCCTCGCCCCCCTG
CAGTGGTACCCAGAAGTGAATCATTTCTGCAAGAAGGTACCCATCATCGTCGTGGGCTGCAAGACTGACCTGTGCAAGGACAAATCACTG

>In-frame_ENST00000253925_ENST00000533360_TCGA-EW-A1J3-01A_PPFIA1_chr11_70118541_+_RHOD_chr11_66833366_length(amino acids)=212AA_start in transcript=65_stop in transcript=703
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQSYTPTVFERYMVNLQVKGKPVHLHIWDTAGQDDYDRLRPLFY

--------------------------------------------------------------
>In-frame_ENST00000389547_ENST00000308831_TCGA-EW-A1J3-01A_PPFIA1_chr11_70118541_+_RHOD_chr11_66833366_length(transcript)=1374nt_BP=462nt
GCTCCTCCTCCGCTCCGCCAGTGTCCGGCCGCGGGCCGGCCTTAGTGACTGGGGCGGCGGGCCCCGGGGCCGCGGCGTGGGGCGGGCAGG
CGGACGCCGGCCGCGGGCTGCTTTCGTCGGCTCCCAAGCTCTCCCGGAGCGAGCAGCCGCCCGCGAGCCGCCGCGGAGCCTCCTCGCCCG
CTCCCGCCGGCGAGCAAGATGATGTGCGAGGTGATGCCGACCATCAGCGAAGCAGAAGGCCCCCCTGGAGGAGGTGGAGGCCATGGTTCC
GGCTCCCCTTCACAGCCAGATGCAGATTCACATTTTGAACAGTTGATGGTCTCCATGCTAGAAGAAAGGGACCGCCTTCTTGATACACTG
AGAGAGACTCAAGAAACGCTGGCCTTAACCCAGGGGAAGTTACACGAGGTTGGTCATGAAAGAGATTCCTTGCAGAGACAGCTCAACACG
GCACTTCCACAGAGCTACACCCCCACGGTGTTTGAGCGGTACATGGTCAACCTGCAAGTGAAAGGCAAACCTGTGCACCTCCACATCTGG
GACACAGCAGGGCAAGATGACTATGACCGCCTGCGGCCCCTGTTCTACCCTGACGCCAGCGTCCTGCTGCTTTGCTTCGATGTCACCAGC
CCGAACAGCTTTGACAACATCTTTAACCGGTGGTACCCAGAAGTGAATCATTTCTGCAAGAAGGTACCCATCATCGTCGTGGGCTGCAAG
ACTGACCTGTGCAAGGACAAATCACTGGTGAACAAGCTCCGAAGAAACGGATTGGAGCCTGTGACCTACCACAGGGGCCAGGAGATGGCG
AGGTCCGTGGGCGCGGTGGCCTACCTCGAGTGCTCGGCTCGGCTCCATGACAACGTCCACGCCGTCTTCCAGGAGGCCGCCGAGGTGGCC
CTCAGCAGCCGCGGTCGCAACTTCTGGCGGCGGATTACCCAGGGCTTTTGCGTGGTGACCTGAGCGGCTCGGGGCGTCCCAGCGACGCGG
GAAGGGGCAGGGCGCTGACCTGCTGCTGAGCTGGCTGGGCTGGACCCGGTCCCTAGGCTGTGACCGCCGAACTCCACTGCAACAGACGGG
CGCCACCAAAGCCAGGCCCTGAGGCCTGGGAGTCCTGGACTGAGAAAGGGGGTTCCTGGGCCCACCTGCTCTGTGTAGGGCTCGTCCTGC
GGTGCCCGAGAATCACTCGCTAACCCCTATGCCCGGTCCCGGACCGACATCCTGGAGCCGCCTGTGCAGCCTGATGCCCCCTCGTGGCTG
CTCCCAGGGCTGCACCTGCCAGGACCTAATGTTCTTAGGTCCCTCTGGCCAGAACCCACACCCGGCCCCTTCCCACCTGTCATACTGGTA

>In-frame_ENST00000389547_ENST00000308831_TCGA-EW-A1J3-01A_PPFIA1_chr11_70118541_+_RHOD_chr11_66833366_length(amino acids)=304AA_start in transcript=48_stop in transcript=962
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQSYTPTVFERYMVNLQVKGKPVHLHIWDTAGQDDYDRLRPLFY
PDASVLLLCFDVTSPNSFDNIFNRWYPEVNHFCKKVPIIVVGCKTDLCKDKSLVNKLRRNGLEPVTYHRGQEMARSVGAVAYLECSARLH

--------------------------------------------------------------
>In-frame_ENST00000389547_ENST00000533360_TCGA-EW-A1J3-01A_PPFIA1_chr11_70118541_+_RHOD_chr11_66833366_length(transcript)=889nt_BP=462nt
GCTCCTCCTCCGCTCCGCCAGTGTCCGGCCGCGGGCCGGCCTTAGTGACTGGGGCGGCGGGCCCCGGGGCCGCGGCGTGGGGCGGGCAGG
CGGACGCCGGCCGCGGGCTGCTTTCGTCGGCTCCCAAGCTCTCCCGGAGCGAGCAGCCGCCCGCGAGCCGCCGCGGAGCCTCCTCGCCCG
CTCCCGCCGGCGAGCAAGATGATGTGCGAGGTGATGCCGACCATCAGCGAAGCAGAAGGCCCCCCTGGAGGAGGTGGAGGCCATGGTTCC
GGCTCCCCTTCACAGCCAGATGCAGATTCACATTTTGAACAGTTGATGGTCTCCATGCTAGAAGAAAGGGACCGCCTTCTTGATACACTG
AGAGAGACTCAAGAAACGCTGGCCTTAACCCAGGGGAAGTTACACGAGGTTGGTCATGAAAGAGATTCCTTGCAGAGACAGCTCAACACG
GCACTTCCACAGAGCTACACCCCCACGGTGTTTGAGCGGTACATGGTCAACCTGCAAGTGAAAGGCAAACCTGTGCACCTCCACATCTGG
GACACAGCAGGGCAAGATGACTATGACCGCCTGCGGCCCCTGTTCTACCCTGACGCCAGCGTCCTGCTGCTTTGCTTCGATGTCACCAGC
CCGAACAGCTTTGACAACATCTTTAACCGGTTTCTCCCTAGGTGCTGGCTTTGCTGATTATCCATATCAGAGCTCAGGCTGGGGAGCAAG
AGAGTGGTCCACTGAGAGGGCCAGAACTCTCCAGGGCTCACACATGCCCCCCACATGCCCCCTCGCCCCCCTGCAGTGGTACCCAGAAGT

>In-frame_ENST00000389547_ENST00000533360_TCGA-EW-A1J3-01A_PPFIA1_chr11_70118541_+_RHOD_chr11_66833366_length(amino acids)=212AA_start in transcript=48_stop in transcript=686
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQSYTPTVFERYMVNLQVKGKPVHLHIWDTAGQDDYDRLRPLFY

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Fusion Gene PPI Analysis for PPFIA1-RHOD


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for PPFIA1-RHOD


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for PPFIA1-RHOD


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource