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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ABR-NXN (FusionGDB2 ID:676)

Fusion Gene Summary for ABR-NXN

check button Fusion gene summary
Fusion gene informationFusion gene name: ABR-NXN
Fusion gene ID: 676
HgeneTgene
Gene symbol

ABR

NXN

Gene ID

29

64359

Gene nameABR activator of RhoGEF and GTPasenucleoredoxin
SynonymsMDBNRX|RRS2|TRG-4
Cytomap

17p13.3

17p13.3

Type of geneprotein-codingprotein-coding
Descriptionactive breakpoint cluster region-related proteinABR, RhoGEF and GTPase activating proteinactive BCR-relatednucleoredoxinnucleoredoxin 1
Modification date2020031320200327
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000302538, ENST00000544583, 
ENST00000572441, ENST00000574437, 
ENST00000291107, ENST00000543210, 
ENST00000536794, ENST00000573895, 
ENST00000336868, ENST00000577098, 
ENST00000575801, ENST00000538650, 
ENST00000537628, 
Fusion gene scores* DoF score23 X 15 X 14=483017 X 15 X 5=1275
# samples 3620
** MAII scorelog2(36/4830*10)=-3.74595437739346
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(20/1275*10)=-2.6724253419715
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ABR [Title/Abstract] AND NXN [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointNXN(882559)-ABR(916404), # samples:5
ABR(953290)-NXN(729318), # samples:2
Anticipated loss of major functional domain due to fusion event.ABR-NXN seems lost the major protein functional domain in Hgene partner, which is a kinase due to the frame-shifted ORF.
ABR-NXN seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneABR

GO:0090630

activation of GTPase activity

7479768


check buttonFusion gene breakpoints across ABR (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across NXN (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-OL-A66P-01AABRchr17

953290

-NXNchr17

729318

-
ChimerDB4LUADTCGA-91-6836-01AABRchr17

1082961

-NXNchr17

729318

-
ChimerDB4SKCMTCGA-D3-A3CC-06AABRchr17

953290

-NXNchr17

729318

-


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Fusion Gene ORF analysis for ABR-NXN

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000302538ENST00000336868ABRchr17

953290

-NXNchr17

729318

-
5CDS-5UTRENST00000302538ENST00000577098ABRchr17

953290

-NXNchr17

729318

-
5CDS-5UTRENST00000302538ENST00000575801ABRchr17

953290

-NXNchr17

729318

-
5CDS-intronENST00000302538ENST00000538650ABRchr17

953290

-NXNchr17

729318

-
5CDS-5UTRENST00000302538ENST00000537628ABRchr17

953290

-NXNchr17

729318

-
Frame-shiftENST00000544583ENST00000336868ABRchr17

953290

-NXNchr17

729318

-
5CDS-5UTRENST00000544583ENST00000577098ABRchr17

953290

-NXNchr17

729318

-
5CDS-5UTRENST00000544583ENST00000575801ABRchr17

953290

-NXNchr17

729318

-
5CDS-intronENST00000544583ENST00000538650ABRchr17

953290

-NXNchr17

729318

-
5CDS-5UTRENST00000544583ENST00000537628ABRchr17

953290

-NXNchr17

729318

-
intron-3CDSENST00000572441ENST00000336868ABRchr17

953290

-NXNchr17

729318

-
intron-5UTRENST00000572441ENST00000577098ABRchr17

953290

-NXNchr17

729318

-
intron-5UTRENST00000572441ENST00000575801ABRchr17

953290

-NXNchr17

729318

-
intron-intronENST00000572441ENST00000538650ABRchr17

953290

-NXNchr17

729318

-
intron-5UTRENST00000572441ENST00000537628ABRchr17

953290

-NXNchr17

729318

-
In-frameENST00000574437ENST00000336868ABRchr17

953290

-NXNchr17

729318

-
5CDS-5UTRENST00000574437ENST00000577098ABRchr17

953290

-NXNchr17

729318

-
5CDS-5UTRENST00000574437ENST00000575801ABRchr17

953290

-NXNchr17

729318

-
5CDS-intronENST00000574437ENST00000538650ABRchr17

953290

-NXNchr17

729318

-
5CDS-5UTRENST00000574437ENST00000537628ABRchr17

953290

-NXNchr17

729318

-
In-frameENST00000291107ENST00000336868ABRchr17

953290

-NXNchr17

729318

-
5CDS-5UTRENST00000291107ENST00000577098ABRchr17

953290

-NXNchr17

729318

-
5CDS-5UTRENST00000291107ENST00000575801ABRchr17

953290

-NXNchr17

729318

-
5CDS-intronENST00000291107ENST00000538650ABRchr17

953290

-NXNchr17

729318

-
5CDS-5UTRENST00000291107ENST00000537628ABRchr17

953290

-NXNchr17

729318

-
intron-3CDSENST00000543210ENST00000336868ABRchr17

953290

-NXNchr17

729318

-
intron-5UTRENST00000543210ENST00000577098ABRchr17

953290

-NXNchr17

729318

-
intron-5UTRENST00000543210ENST00000575801ABRchr17

953290

-NXNchr17

729318

-
intron-intronENST00000543210ENST00000538650ABRchr17

953290

-NXNchr17

729318

-
intron-5UTRENST00000543210ENST00000537628ABRchr17

953290

-NXNchr17

729318

-
In-frameENST00000536794ENST00000336868ABRchr17

953290

-NXNchr17

729318

-
5CDS-5UTRENST00000536794ENST00000577098ABRchr17

953290

-NXNchr17

729318

-
5CDS-5UTRENST00000536794ENST00000575801ABRchr17

953290

-NXNchr17

729318

-
5CDS-intronENST00000536794ENST00000538650ABRchr17

953290

-NXNchr17

729318

-
5CDS-5UTRENST00000536794ENST00000537628ABRchr17

953290

-NXNchr17

729318

-
intron-3CDSENST00000573895ENST00000336868ABRchr17

953290

-NXNchr17

729318

-
intron-5UTRENST00000573895ENST00000577098ABRchr17

953290

-NXNchr17

729318

-
intron-5UTRENST00000573895ENST00000575801ABRchr17

953290

-NXNchr17

729318

-
intron-intronENST00000573895ENST00000538650ABRchr17

953290

-NXNchr17

729318

-
intron-5UTRENST00000573895ENST00000537628ABRchr17

953290

-NXNchr17

729318

-
In-frameENST00000302538ENST00000336868ABRchr17

1082961

-NXNchr17

729318

-
5CDS-5UTRENST00000302538ENST00000577098ABRchr17

1082961

-NXNchr17

729318

-
5CDS-5UTRENST00000302538ENST00000575801ABRchr17

1082961

-NXNchr17

729318

-
5CDS-intronENST00000302538ENST00000538650ABRchr17

1082961

-NXNchr17

729318

-
5CDS-5UTRENST00000302538ENST00000537628ABRchr17

1082961

-NXNchr17

729318

-
intron-3CDSENST00000544583ENST00000336868ABRchr17

1082961

-NXNchr17

729318

-
intron-5UTRENST00000544583ENST00000577098ABRchr17

1082961

-NXNchr17

729318

-
intron-5UTRENST00000544583ENST00000575801ABRchr17

1082961

-NXNchr17

729318

-
intron-intronENST00000544583ENST00000538650ABRchr17

1082961

-NXNchr17

729318

-
intron-5UTRENST00000544583ENST00000537628ABRchr17

1082961

-NXNchr17

729318

-
intron-3CDSENST00000572441ENST00000336868ABRchr17

1082961

-NXNchr17

729318

-
intron-5UTRENST00000572441ENST00000577098ABRchr17

1082961

-NXNchr17

729318

-
intron-5UTRENST00000572441ENST00000575801ABRchr17

1082961

-NXNchr17

729318

-
intron-intronENST00000572441ENST00000538650ABRchr17

1082961

-NXNchr17

729318

-
intron-5UTRENST00000572441ENST00000537628ABRchr17

1082961

-NXNchr17

729318

-
intron-3CDSENST00000574437ENST00000336868ABRchr17

1082961

-NXNchr17

729318

-
intron-5UTRENST00000574437ENST00000577098ABRchr17

1082961

-NXNchr17

729318

-
intron-5UTRENST00000574437ENST00000575801ABRchr17

1082961

-NXNchr17

729318

-
intron-intronENST00000574437ENST00000538650ABRchr17

1082961

-NXNchr17

729318

-
intron-5UTRENST00000574437ENST00000537628ABRchr17

1082961

-NXNchr17

729318

-
intron-3CDSENST00000291107ENST00000336868ABRchr17

1082961

-NXNchr17

729318

-
intron-5UTRENST00000291107ENST00000577098ABRchr17

1082961

-NXNchr17

729318

-
intron-5UTRENST00000291107ENST00000575801ABRchr17

1082961

-NXNchr17

729318

-
intron-intronENST00000291107ENST00000538650ABRchr17

1082961

-NXNchr17

729318

-
intron-5UTRENST00000291107ENST00000537628ABRchr17

1082961

-NXNchr17

729318

-
intron-3CDSENST00000543210ENST00000336868ABRchr17

1082961

-NXNchr17

729318

-
intron-5UTRENST00000543210ENST00000577098ABRchr17

1082961

-NXNchr17

729318

-
intron-5UTRENST00000543210ENST00000575801ABRchr17

1082961

-NXNchr17

729318

-
intron-intronENST00000543210ENST00000538650ABRchr17

1082961

-NXNchr17

729318

-
intron-5UTRENST00000543210ENST00000537628ABRchr17

1082961

-NXNchr17

729318

-
intron-3CDSENST00000536794ENST00000336868ABRchr17

1082961

-NXNchr17

729318

-
intron-5UTRENST00000536794ENST00000577098ABRchr17

1082961

-NXNchr17

729318

-
intron-5UTRENST00000536794ENST00000575801ABRchr17

1082961

-NXNchr17

729318

-
intron-intronENST00000536794ENST00000538650ABRchr17

1082961

-NXNchr17

729318

-
intron-5UTRENST00000536794ENST00000537628ABRchr17

1082961

-NXNchr17

729318

-
intron-3CDSENST00000573895ENST00000336868ABRchr17

1082961

-NXNchr17

729318

-
intron-5UTRENST00000573895ENST00000577098ABRchr17

1082961

-NXNchr17

729318

-
intron-5UTRENST00000573895ENST00000575801ABRchr17

1082961

-NXNchr17

729318

-
intron-intronENST00000573895ENST00000538650ABRchr17

1082961

-NXNchr17

729318

-
intron-5UTRENST00000573895ENST00000537628ABRchr17

1082961

-NXNchr17

729318

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000302538ABRchr17953290-ENST00000336868NXNchr17729318-452219381472885912
ENST00000574437ABRchr17953290-ENST00000336868NXNchr17729318-470221181233065980
ENST00000291107ABRchr17953290-ENST00000336868NXNchr17729318-42961712322659875
ENST00000536794ABRchr17953290-ENST00000336868NXNchr17729318-400814241402371743
ENST00000302538ABRchr171082961-ENST00000336868NXNchr17729318-27922082981155285

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000302538ENST00000336868ABRchr17953290-NXNchr17729318-0.001393780.99860626
ENST00000574437ENST00000336868ABRchr17953290-NXNchr17729318-0.0021883150.99781173
ENST00000291107ENST00000336868ABRchr17953290-NXNchr17729318-0.0029501570.9970498
ENST00000536794ENST00000336868ABRchr17953290-NXNchr17729318-0.0100140150.989986
ENST00000302538ENST00000336868ABRchr171082961-NXNchr17729318-0.0028109580.9971891

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Fusion Genomic Features for ABR-NXN


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for ABR-NXN


check button Go to

FGviewer for the breakpoints of chr17:953290-chr17:729318

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneABRchr17:953290chr17:729318ENST00000291107-1522417_420560.0823.0Compositional biasNote=Poly-Leu
HgeneABRchr17:953290chr17:729318ENST00000302538-1623417_420597.0860.0Compositional biasNote=Poly-Leu
HgeneABRchr17:953290chr17:729318ENST00000544583-1623417_420551.0814.0Compositional biasNote=Poly-Leu
HgeneABRchr17:953290chr17:729318ENST00000574437-1522417_420551.0814.0Compositional biasNote=Poly-Leu
HgeneABRchr17:953290chr17:729318ENST00000291107-1522301_459560.0823.0DomainPH
HgeneABRchr17:953290chr17:729318ENST00000291107-152291_284560.0823.0DomainDH
HgeneABRchr17:953290chr17:729318ENST00000302538-1623301_459597.0860.0DomainPH
HgeneABRchr17:953290chr17:729318ENST00000302538-162391_284597.0860.0DomainDH
HgeneABRchr17:953290chr17:729318ENST00000544583-1623301_459551.0814.0DomainPH
HgeneABRchr17:953290chr17:729318ENST00000544583-162391_284551.0814.0DomainDH
HgeneABRchr17:953290chr17:729318ENST00000574437-1522301_459551.0814.0DomainPH
HgeneABRchr17:953290chr17:729318ENST00000574437-152291_284551.0814.0DomainDH
TgeneNXNchr17:1082961chr17:729318ENST0000033686808167_321120.0436.0DomainThioredoxin
TgeneNXNchr17:1082961chr17:729318ENST0000053762808167_3210187.0DomainThioredoxin
TgeneNXNchr17:1082961chr17:729318ENST0000057580108167_32112.0328.0DomainThioredoxin
TgeneNXNchr17:953290chr17:729318ENST0000033686808167_321120.0436.0DomainThioredoxin
TgeneNXNchr17:953290chr17:729318ENST0000053762808167_3210187.0DomainThioredoxin
TgeneNXNchr17:953290chr17:729318ENST0000057580108167_32112.0328.0DomainThioredoxin

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneABRchr17:1082961chr17:729318ENST00000291107-122417_4200823.0Compositional biasNote=Poly-Leu
HgeneABRchr17:1082961chr17:729318ENST00000302538-123417_42020.333333333333332860.0Compositional biasNote=Poly-Leu
HgeneABRchr17:1082961chr17:729318ENST00000543210-18417_4200311.0Compositional biasNote=Poly-Leu
HgeneABRchr17:1082961chr17:729318ENST00000544583-123417_4200814.0Compositional biasNote=Poly-Leu
HgeneABRchr17:1082961chr17:729318ENST00000574437-122417_4200814.0Compositional biasNote=Poly-Leu
HgeneABRchr17:953290chr17:729318ENST00000543210-18417_4200311.0Compositional biasNote=Poly-Leu
HgeneABRchr17:1082961chr17:729318ENST00000291107-122301_4590823.0DomainPH
HgeneABRchr17:1082961chr17:729318ENST00000291107-122484_6130823.0DomainC2
HgeneABRchr17:1082961chr17:729318ENST00000291107-122647_8450823.0DomainRho-GAP
HgeneABRchr17:1082961chr17:729318ENST00000291107-12291_2840823.0DomainDH
HgeneABRchr17:1082961chr17:729318ENST00000302538-123301_45920.333333333333332860.0DomainPH
HgeneABRchr17:1082961chr17:729318ENST00000302538-123484_61320.333333333333332860.0DomainC2
HgeneABRchr17:1082961chr17:729318ENST00000302538-123647_84520.333333333333332860.0DomainRho-GAP
HgeneABRchr17:1082961chr17:729318ENST00000302538-12391_28420.333333333333332860.0DomainDH
HgeneABRchr17:1082961chr17:729318ENST00000543210-18301_4590311.0DomainPH
HgeneABRchr17:1082961chr17:729318ENST00000543210-18484_6130311.0DomainC2
HgeneABRchr17:1082961chr17:729318ENST00000543210-18647_8450311.0DomainRho-GAP
HgeneABRchr17:1082961chr17:729318ENST00000543210-1891_2840311.0DomainDH
HgeneABRchr17:1082961chr17:729318ENST00000544583-123301_4590814.0DomainPH
HgeneABRchr17:1082961chr17:729318ENST00000544583-123484_6130814.0DomainC2
HgeneABRchr17:1082961chr17:729318ENST00000544583-123647_8450814.0DomainRho-GAP
HgeneABRchr17:1082961chr17:729318ENST00000544583-12391_2840814.0DomainDH
HgeneABRchr17:1082961chr17:729318ENST00000574437-122301_4590814.0DomainPH
HgeneABRchr17:1082961chr17:729318ENST00000574437-122484_6130814.0DomainC2
HgeneABRchr17:1082961chr17:729318ENST00000574437-122647_8450814.0DomainRho-GAP
HgeneABRchr17:1082961chr17:729318ENST00000574437-12291_2840814.0DomainDH
HgeneABRchr17:953290chr17:729318ENST00000291107-1522484_613560.0823.0DomainC2
HgeneABRchr17:953290chr17:729318ENST00000291107-1522647_845560.0823.0DomainRho-GAP
HgeneABRchr17:953290chr17:729318ENST00000302538-1623484_613597.0860.0DomainC2
HgeneABRchr17:953290chr17:729318ENST00000302538-1623647_845597.0860.0DomainRho-GAP
HgeneABRchr17:953290chr17:729318ENST00000543210-18301_4590311.0DomainPH
HgeneABRchr17:953290chr17:729318ENST00000543210-18484_6130311.0DomainC2
HgeneABRchr17:953290chr17:729318ENST00000543210-18647_8450311.0DomainRho-GAP
HgeneABRchr17:953290chr17:729318ENST00000543210-1891_2840311.0DomainDH
HgeneABRchr17:953290chr17:729318ENST00000544583-1623484_613551.0814.0DomainC2
HgeneABRchr17:953290chr17:729318ENST00000544583-1623647_845551.0814.0DomainRho-GAP
HgeneABRchr17:953290chr17:729318ENST00000574437-1522484_613551.0814.0DomainC2
HgeneABRchr17:953290chr17:729318ENST00000574437-1522647_845551.0814.0DomainRho-GAP


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Fusion Gene Sequence for ABR-NXN


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000302538_ENST00000336868_TCGA-OL-A66P-01A_ABR_chr17_953290_-_NXN_chr17_729318_length(transcript)=4522nt_BP=1938nt
GCCCCGCGCTCCTCCCGGGGACCTGGTTCCCGGCCTCCTCGCCCCTCCGCGCTCGCAACTTCGGCCTCCCCCGGCTCCCGCCCGCTCTCC
CTCCTTTGTTGCGCGATGAGGGTCGGGTTTCGGATCTGACCGAGCCGCCGCCGCGGGATGGAGCCGCTCAGCCACCGGGGCCTGCCGCGC
CTGTCCTGGATCGACACCCTCTACAGCAACTTCAGCTACGGGACGGACGAGTACGACGGAGAGGGGAATGAGGAGCAGAAGGGGCCCCCG
GAGGGCTCAGAGACCATGCCGTACATCGATGAGTCGCCCACCATGTCCCCGCAGCTCAGCGCCCGCAGCCAGGGCGGGGGGGATGGCGTC
TCCCCGACTCCACCTGAGGGACTGGCTCCTGGGGTGGAAGCAGGGAAAGGCCTGGAGATGAGGAAGCTGGTTCTCTCGGGGTTCTTGGCC
AGCGAAGAGATCTACATTAACCAGCTGGAAGCCCTGTTGCTGCCCATGAAACCCCTGAAGGCCACCGCCACCACCTCCCAGCCCGTGCTC
ACCATCCAGCAGATCGAGACCATCTTCTACAAGATCCAGGACATCTATGAGATCCACAAGGAGTTCTATGACAACCTGTGCCCCAAGGTG
CAACAGTGGGACAGCCAGGTCACCATGGGCCACCTCTTCCAGAAGCTGGCCAGCCAGCTCGGTGTGTACAAAGCGTTTGTCGATAACTAT
AAAGTCGCTCTGGAGACAGCTGAGAAGTGCAGCCAGTCCAACAACCAGTTCCAGAAGATCTCAGAGGAACTCAAAGTGAAAGGTCCCAAG
GACTCCAAGGACAGCCACACGTCTGTCACCATGGAAGCTCTGCTCTACAAGCCCATTGACCGGGTCACTCGGAGCACCCTAGTCCTACAC
GACCTGCTGAAGCACACACCTGTGGACCACCCCGACTACCCGCTGCTGCAGGATGCCCTCCGCATCTCCCAGAACTTCCTGTCCAGCATC
AACGAGGACATCGACCCCCGCCGGACTGCAGTGACAACGCCCAAGGGGGAGACGCGACAGCTGGTGAAGGACGGCTTCCTGGTGGAAGTG
TCAGAGAGCTCCCGGAAGCTGCGGCACGTCTTCCTCTTTACAGATGTCCTACTGTGTGCCAAGCTGAAGAAGACCTCTGCAGGGAAGCAC
CAGCAGTATGACTGTAAGTGGTACATCCCCCTGGCCGACCTGGTGTTTCCATCCCCCGAGGAGTCTGAGGCCAGCCCCCAGGTGCACCCC
TTCCCAGACCATGAGCTGGAGGACATGAAGATGAAGATCTCTGCCCTCAAGAGTGAAATCCAGAAGGAGAAAGCCAACAAAGGCCAGAGC
CGGGCCATCGAGCGCCTGAAGAAGAAGATGTTTGAGAATGAGTTCCTGCTGCTGCTCAACTCCCCCACAATCCCGTTCAGGATCCACAAT
CGGAATGGAAAGAGTTACCTGTTCCTACTGTCCTCGGACTACGAGAGGTCAGAGTGGAGAGAAGCAATTCAGAAACTACAGAAGAAGGAT
CTCCAGGCCTTTGTCCTGAGCTCAGTGGAGCTCCAGGTGCTCACAGGATCCTGTTTCAAGCTTAGGACTGTACACAACATTCCTGTCACC
AGCAATAAAGACGACGATGAGTCTCCAGGACTCTATGGCTTCCTTCATGTCATCGTCCACTCTGCCAAGGGATTTAAGCAATCAGCCAAC
CTGTACTGTACCCTGGAGGTGGATTCCTTCGGCTATTTTGTCAGCAAAGCCAAAACCAGGGTGTTCCGGGACACAGCGGAGCCCAAGTGG
GATGAGGAGTTTGAGATCGAGCTGGAGGGCTCCCAGTCCCTGAGGATCCTGTGCTATGAGAAGTGCTATGACAAGACCAAGGTCAACAAG
GACAACAATGAGATCGTGGACAAGATCATGGGCAAAGGACAGATCCAGCTCAAACTTTGGAACAAATACCGAATTTCCAACATTCCATCA
CTAATATTCCTCGACGCCACCACTGGGAAGGTTGTGTGCAGGAACGGGCTGCTGGTGATCCGAGATGACCCAGAAGGTCTGGAGTTCCCC
TGGGGACCGAAACCCTTCAGGGAAGTCATTGCAGGGCCCTTGCTTAGAAACAATGGGCAGTCTCTGGAGAGCAGCAGCCTGGAGGGGTCT
CACGTGGGCGTCTATTTCTCCGCACATTGGTGTCCGCCCTGCCGAAGCCTCACCCGGGTCCTGGTGGAATCCTACCGGAAGATCAAGGAG
GCAGGCCAGAACTTCGAGATCATCTTCGTTAGTGCAGACAGGTCGGAGGAGTCCTTCAAACAGTACTTCAGTGAGATGCCCTGGCTCGCC
GTCCCCTACACGGATGAGGCCCGGCGGTCGCGCCTCAACCGGCTGTACGGAATCCAAGGCATCCCCACGCTCATCATGCTGGACCCGCAG
GGCGAGGTGATCACGCGGCAGGGGCGGGTGGAGGTGCTGAACGACGAGGACTGCCGGGAGTTCCCCTGGCACCCCAAGCCCGTGCTGGAG
CTCTCCGACTCCAACGCCGCGCAGCTTAACGAGGGCCCCTGCCTCGTCCTTTTTGTAGATTCTGAGGATGACGGAGAGTCCGAGGCGGCC
AAGCAGCTGATTCAGCCGATAGCTGAGAAAATCATTGCCAAGTACAAAGCCAAAGAGGAGGAGGCACCCCTTCTGTTCTTCGTAGCCGGG
GAGGATGACATGACTGACTCCCTGCGAGATTACACCAACCTGCCTGAGGCTGCCCCTTTGCTCACCATCCTGGACATGTCAGCCCGGGCC
AAGTACGTGATGGACGTGGAGGAGATCACCCCCGCCATCGTGGAGGCCTTTGTGAATGACTTCCTAGCAGAGAAGCTCAAACCGGAGCCC
ATCTAGCGTGGCTCCGGCCTCCTGAGACGTTATTTAAAACTCAGCCTTCTCCTCCTCCCCCTCCTTCCTTCCGCCCTTGGACTTACCCAG
CGTGCCCCGAATCCCACCACCCAAGTGTCCAGCCTCTCTGTGGTGCCTTGTTTCTGCAGTAAACTCCTCAGCCAGCACCCTGGGGTGTGG
AATCAGCAGCGGCAGAGTCCACCGTGTTTGGAGACTCTGTTTGGGAGCACGGGATGGCCGGGGGCCCGGCCAGAGCGGGGCTGCATGGCT
TTCGCAAAGTCACTAGCTTTTGGTGAAGGATCTGCCAGGGTGTCCTGGGCAGAGTGAGCGTGGAGGGCCGGTGGGTCCCGCTCGGGCTCT
GACTCTGACGTCGGCACACACGGCCCCGGACGGCCAGAGGGGAACCGCCGGGTGACACCTGCGTGGAGGCTGAGCTGAGAAAGGGCCTCC
GCTTAGAGCTGCGGGTGAGGACGTCCTTTTCTAAGCAACACAGTCTTCCTCGGTCTGAGAGAAAAGCAGCCCACTCTTGTGTTCTCAGGC
AGGGGATCTCCAAATGCAAAAGGAAGCTTGTAGAGGTTTTTTGGGTGAGAAGAAAAATGTAGCTAAGGTAATGGTTCATATCATACAAAC
AGCTCCCACGATCCTGAAATTCTGTTAACGAATCCTTCTCTTTGGACATCTTCCCAAGAAACTTAGCCCTGAGTCCTAGGAGGAGCACCT
CTGCACCAGCACGGACCTCTCGCTCCACCCAGCTCTGTGCCCAAGGCCCCTGATCTCTGCTGAGGTGCCCACACCCACGTTCGATCACCC
CTGCCATTCCCTTTTATTTTCTTTTTTTTGAGATGGAGTCTTGCTCTGTCGCCCAGGCTGGAGTGCAGTGGCACCATCTTGGCTCACTTC
AACCTCCGCCCCCAAGGTTCAAGTGATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGCACCCGCCACCGTACCTGGCTAATT
TTTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACTCCTGACCTCAGGTGATCCACCCGCCTCGGCCTCC
CAAAGTGCTGGGATTACAGGCGTGAGCCGCCGTGCCCGGCCCCCTTTTCTTTTCAAAGCAGAACTACAAAGATGAGAAATTACCAGAAGC
CTCGCCTTTTCCTAAGCACCAGCGGAAGGAGCTGTGCCCCGGGATGGAGTGAGGGTGGAGGGCGCGTCAGCCACGGGTGGGCCTTGTGTC
GCCTTGTATCGGCCCAGGTAGGTTGTTGGCCTCTTACTTGGGCTGACCTGACCCCCGAAAGAGAAACAGACAACTCTGTTCTCAGGATTG
GGGATGGACGGCTTCGGCCAAGCGTTTTAGCCTCATTCACTCAGGCCCCACTCAGCACTCTGCCAGCCAAGACCATTGATTTGGAAAATC
CGGTCCCCACCCGCTAATGAGCTGTTGACACTGTTGTTCCTTGCTGAATTGGATTGTTGACTTGTAGTTCAGAGGCGTACAACTAGTTGG
CGATTAGACTTGTTATGTGATGTTACCAGCCTGAAATGCGATCACCCCGTAGGAAATAAAGCAGGCATCTCTGGACCTCATCCACCCTGG

>In-frame_ENST00000302538_ENST00000336868_TCGA-OL-A66P-01A_ABR_chr17_953290_-_NXN_chr17_729318_length(amino acids)=912AA_start in transcript=147_stop in transcript=2885
MEPLSHRGLPRLSWIDTLYSNFSYGTDEYDGEGNEEQKGPPEGSETMPYIDESPTMSPQLSARSQGGGDGVSPTPPEGLAPGVEAGKGLE
MRKLVLSGFLASEEIYINQLEALLLPMKPLKATATTSQPVLTIQQIETIFYKIQDIYEIHKEFYDNLCPKVQQWDSQVTMGHLFQKLASQ
LGVYKAFVDNYKVALETAEKCSQSNNQFQKISEELKVKGPKDSKDSHTSVTMEALLYKPIDRVTRSTLVLHDLLKHTPVDHPDYPLLQDA
LRISQNFLSSINEDIDPRRTAVTTPKGETRQLVKDGFLVEVSESSRKLRHVFLFTDVLLCAKLKKTSAGKHQQYDCKWYIPLADLVFPSP
EESEASPQVHPFPDHELEDMKMKISALKSEIQKEKANKGQSRAIERLKKKMFENEFLLLLNSPTIPFRIHNRNGKSYLFLLSSDYERSEW
REAIQKLQKKDLQAFVLSSVELQVLTGSCFKLRTVHNIPVTSNKDDDESPGLYGFLHVIVHSAKGFKQSANLYCTLEVDSFGYFVSKAKT
RVFRDTAEPKWDEEFEIELEGSQSLRILCYEKCYDKTKVNKDNNEIVDKIMGKGQIQLKLWNKYRISNIPSLIFLDATTGKVVCRNGLLV
IRDDPEGLEFPWGPKPFREVIAGPLLRNNGQSLESSSLEGSHVGVYFSAHWCPPCRSLTRVLVESYRKIKEAGQNFEIIFVSADRSEESF
KQYFSEMPWLAVPYTDEARRSRLNRLYGIQGIPTLIMLDPQGEVITRQGRVEVLNDEDCREFPWHPKPVLELSDSNAAQLNEGPCLVLFV
DSEDDGESEAAKQLIQPIAEKIIAKYKAKEEEAPLLFFVAGEDDMTDSLRDYTNLPEAAPLLTILDMSARAKYVMDVEEITPAIVEAFVN

--------------------------------------------------------------
>In-frame_ENST00000574437_ENST00000336868_TCGA-OL-A66P-01A_ABR_chr17_953290_-_NXN_chr17_729318_length(transcript)=4702nt_BP=2118nt
ATAAAAAGCAAAATGGTGACTCAGAGAGGAGAGTTGGAAGCGTCCTGCCTCTTGCTCCCACTGTTAATTTTTACACTTGGAATTAGGCAG
AAGGCAAAGAAAACAGCAGCTTGAAATACGCGGCTGACATGCTCTTCATCGGGTAGCAACAGCAGAGCCGCTCCTCCCCGCCTCCCAGCA
GCCCCGGAGCGGGCAGGGCCCGGTGCCTGCTGGCTCTCCCCCGCCCCTCACCAGGCCCAGGCCCCCGCACAGCCCCCGCCCGGGCCAGGC
GTGGATGGTGCGGCCGGGGCCATGGCTGCCGGGGGCCGCCGCCGGCGCCCACTACGCTACCAGTCCCTGGCAGCTCTGGTGGAGGATTCT
CAGTGGCCTTTCTTGTTCCTTGTCTCAGACTTCAGCTACGGGACGGACGAGTACGACGGAGAGGGGAATGAGGAGCAGAAGGGGCCCCCG
GAGGGCTCAGAGACCATGCCGTACATCGATGAGTCGCCCACCATGTCCCCGCAGCTCAGCGCCCGCAGCCAGGGCGGGGGGGATGGCGTC
TCCCCGACTCCACCTGAGGGACTGGCTCCTGGGGTGGAAGCAGGGAAAGGCCTGGAGATGAGGAAGCTGGTTCTCTCGGGGTTCTTGGCC
AGCGAAGAGATCTACATTAACCAGCTGGAAGCCCTGTTGCTGCCCATGAAACCCCTGAAGGCCACCGCCACCACCTCCCAGCCCGTGCTC
ACCATCCAGCAGATCGAGACCATCTTCTACAAGATCCAGGACATCTATGAGATCCACAAGGAGTTCTATGACAACCTGTGCCCCAAGGTG
CAACAGTGGGACAGCCAGGTCACCATGGGCCACCTCTTCCAGAAGCTGGCCAGCCAGCTCGGTGTGTACAAAGCGTTTGTCGATAACTAT
AAAGTCGCTCTGGAGACAGCTGAGAAGTGCAGCCAGTCCAACAACCAGTTCCAGAAGATCTCAGAGGAACTCAAAGTGAAAGGTCCCAAG
GACTCCAAGGACAGCCACACGTCTGTCACCATGGAAGCTCTGCTCTACAAGCCCATTGACCGGGTCACTCGGAGCACCCTAGTCCTACAC
GACCTGCTGAAGCACACACCTGTGGACCACCCCGACTACCCGCTGCTGCAGGATGCCCTCCGCATCTCCCAGAACTTCCTGTCCAGCATC
AACGAGGACATCGACCCCCGCCGGACTGCAGTGACAACGCCCAAGGGGGAGACGCGACAGCTGGTGAAGGACGGCTTCCTGGTGGAAGTG
TCAGAGAGCTCCCGGAAGCTGCGGCACGTCTTCCTCTTTACAGATGTCCTACTGTGTGCCAAGCTGAAGAAGACCTCTGCAGGGAAGCAC
CAGCAGTATGACTGTAAGTGGTACATCCCCCTGGCCGACCTGGTGTTTCCATCCCCCGAGGAGTCTGAGGCCAGCCCCCAGGTGCACCCC
TTCCCAGACCATGAGCTGGAGGACATGAAGATGAAGATCTCTGCCCTCAAGAGTGAAATCCAGAAGGAGAAAGCCAACAAAGGCCAGAGC
CGGGCCATCGAGCGCCTGAAGAAGAAGATGTTTGAGAATGAGTTCCTGCTGCTGCTCAACTCCCCCACAATCCCGTTCAGGATCCACAAT
CGGAATGGAAAGAGTTACCTGTTCCTACTGTCCTCGGACTACGAGAGGTCAGAGTGGAGAGAAGCAATTCAGAAACTACAGAAGAAGGAT
CTCCAGGCCTTTGTCCTGAGCTCAGTGGAGCTCCAGGTGCTCACAGGATCCTGTTTCAAGCTTAGGACTGTACACAACATTCCTGTCACC
AGCAATAAAGACGACGATGAGTCTCCAGGACTCTATGGCTTCCTTCATGTCATCGTCCACTCTGCCAAGGGATTTAAGCAATCAGCCAAC
CTGTACTGTACCCTGGAGGTGGATTCCTTCGGCTATTTTGTCAGCAAAGCCAAAACCAGGGTGTTCCGGGACACAGCGGAGCCCAAGTGG
GATGAGGAGTTTGAGATCGAGCTGGAGGGCTCCCAGTCCCTGAGGATCCTGTGCTATGAGAAGTGCTATGACAAGACCAAGGTCAACAAG
GACAACAATGAGATCGTGGACAAGATCATGGGCAAAGGACAGATCCAGCTCAAACTTTGGAACAAATACCGAATTTCCAACATTCCATCA
CTAATATTCCTCGACGCCACCACTGGGAAGGTTGTGTGCAGGAACGGGCTGCTGGTGATCCGAGATGACCCAGAAGGTCTGGAGTTCCCC
TGGGGACCGAAACCCTTCAGGGAAGTCATTGCAGGGCCCTTGCTTAGAAACAATGGGCAGTCTCTGGAGAGCAGCAGCCTGGAGGGGTCT
CACGTGGGCGTCTATTTCTCCGCACATTGGTGTCCGCCCTGCCGAAGCCTCACCCGGGTCCTGGTGGAATCCTACCGGAAGATCAAGGAG
GCAGGCCAGAACTTCGAGATCATCTTCGTTAGTGCAGACAGGTCGGAGGAGTCCTTCAAACAGTACTTCAGTGAGATGCCCTGGCTCGCC
GTCCCCTACACGGATGAGGCCCGGCGGTCGCGCCTCAACCGGCTGTACGGAATCCAAGGCATCCCCACGCTCATCATGCTGGACCCGCAG
GGCGAGGTGATCACGCGGCAGGGGCGGGTGGAGGTGCTGAACGACGAGGACTGCCGGGAGTTCCCCTGGCACCCCAAGCCCGTGCTGGAG
CTCTCCGACTCCAACGCCGCGCAGCTTAACGAGGGCCCCTGCCTCGTCCTTTTTGTAGATTCTGAGGATGACGGAGAGTCCGAGGCGGCC
AAGCAGCTGATTCAGCCGATAGCTGAGAAAATCATTGCCAAGTACAAAGCCAAAGAGGAGGAGGCACCCCTTCTGTTCTTCGTAGCCGGG
GAGGATGACATGACTGACTCCCTGCGAGATTACACCAACCTGCCTGAGGCTGCCCCTTTGCTCACCATCCTGGACATGTCAGCCCGGGCC
AAGTACGTGATGGACGTGGAGGAGATCACCCCCGCCATCGTGGAGGCCTTTGTGAATGACTTCCTAGCAGAGAAGCTCAAACCGGAGCCC
ATCTAGCGTGGCTCCGGCCTCCTGAGACGTTATTTAAAACTCAGCCTTCTCCTCCTCCCCCTCCTTCCTTCCGCCCTTGGACTTACCCAG
CGTGCCCCGAATCCCACCACCCAAGTGTCCAGCCTCTCTGTGGTGCCTTGTTTCTGCAGTAAACTCCTCAGCCAGCACCCTGGGGTGTGG
AATCAGCAGCGGCAGAGTCCACCGTGTTTGGAGACTCTGTTTGGGAGCACGGGATGGCCGGGGGCCCGGCCAGAGCGGGGCTGCATGGCT
TTCGCAAAGTCACTAGCTTTTGGTGAAGGATCTGCCAGGGTGTCCTGGGCAGAGTGAGCGTGGAGGGCCGGTGGGTCCCGCTCGGGCTCT
GACTCTGACGTCGGCACACACGGCCCCGGACGGCCAGAGGGGAACCGCCGGGTGACACCTGCGTGGAGGCTGAGCTGAGAAAGGGCCTCC
GCTTAGAGCTGCGGGTGAGGACGTCCTTTTCTAAGCAACACAGTCTTCCTCGGTCTGAGAGAAAAGCAGCCCACTCTTGTGTTCTCAGGC
AGGGGATCTCCAAATGCAAAAGGAAGCTTGTAGAGGTTTTTTGGGTGAGAAGAAAAATGTAGCTAAGGTAATGGTTCATATCATACAAAC
AGCTCCCACGATCCTGAAATTCTGTTAACGAATCCTTCTCTTTGGACATCTTCCCAAGAAACTTAGCCCTGAGTCCTAGGAGGAGCACCT
CTGCACCAGCACGGACCTCTCGCTCCACCCAGCTCTGTGCCCAAGGCCCCTGATCTCTGCTGAGGTGCCCACACCCACGTTCGATCACCC
CTGCCATTCCCTTTTATTTTCTTTTTTTTGAGATGGAGTCTTGCTCTGTCGCCCAGGCTGGAGTGCAGTGGCACCATCTTGGCTCACTTC
AACCTCCGCCCCCAAGGTTCAAGTGATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGCACCCGCCACCGTACCTGGCTAATT
TTTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACTCCTGACCTCAGGTGATCCACCCGCCTCGGCCTCC
CAAAGTGCTGGGATTACAGGCGTGAGCCGCCGTGCCCGGCCCCCTTTTCTTTTCAAAGCAGAACTACAAAGATGAGAAATTACCAGAAGC
CTCGCCTTTTCCTAAGCACCAGCGGAAGGAGCTGTGCCCCGGGATGGAGTGAGGGTGGAGGGCGCGTCAGCCACGGGTGGGCCTTGTGTC
GCCTTGTATCGGCCCAGGTAGGTTGTTGGCCTCTTACTTGGGCTGACCTGACCCCCGAAAGAGAAACAGACAACTCTGTTCTCAGGATTG
GGGATGGACGGCTTCGGCCAAGCGTTTTAGCCTCATTCACTCAGGCCCCACTCAGCACTCTGCCAGCCAAGACCATTGATTTGGAAAATC
CGGTCCCCACCCGCTAATGAGCTGTTGACACTGTTGTTCCTTGCTGAATTGGATTGTTGACTTGTAGTTCAGAGGCGTACAACTAGTTGG
CGATTAGACTTGTTATGTGATGTTACCAGCCTGAAATGCGATCACCCCGTAGGAAATAAAGCAGGCATCTCTGGACCTCATCCACCCTGG

>In-frame_ENST00000574437_ENST00000336868_TCGA-OL-A66P-01A_ABR_chr17_953290_-_NXN_chr17_729318_length(amino acids)=980AA_start in transcript=123_stop in transcript=3065
MTCSSSGSNSRAAPPRLPAAPERAGPGACWLSPAPHQAQAPAQPPPGPGVDGAAGAMAAGGRRRRPLRYQSLAALVEDSQWPFLFLVSDF
SYGTDEYDGEGNEEQKGPPEGSETMPYIDESPTMSPQLSARSQGGGDGVSPTPPEGLAPGVEAGKGLEMRKLVLSGFLASEEIYINQLEA
LLLPMKPLKATATTSQPVLTIQQIETIFYKIQDIYEIHKEFYDNLCPKVQQWDSQVTMGHLFQKLASQLGVYKAFVDNYKVALETAEKCS
QSNNQFQKISEELKVKGPKDSKDSHTSVTMEALLYKPIDRVTRSTLVLHDLLKHTPVDHPDYPLLQDALRISQNFLSSINEDIDPRRTAV
TTPKGETRQLVKDGFLVEVSESSRKLRHVFLFTDVLLCAKLKKTSAGKHQQYDCKWYIPLADLVFPSPEESEASPQVHPFPDHELEDMKM
KISALKSEIQKEKANKGQSRAIERLKKKMFENEFLLLLNSPTIPFRIHNRNGKSYLFLLSSDYERSEWREAIQKLQKKDLQAFVLSSVEL
QVLTGSCFKLRTVHNIPVTSNKDDDESPGLYGFLHVIVHSAKGFKQSANLYCTLEVDSFGYFVSKAKTRVFRDTAEPKWDEEFEIELEGS
QSLRILCYEKCYDKTKVNKDNNEIVDKIMGKGQIQLKLWNKYRISNIPSLIFLDATTGKVVCRNGLLVIRDDPEGLEFPWGPKPFREVIA
GPLLRNNGQSLESSSLEGSHVGVYFSAHWCPPCRSLTRVLVESYRKIKEAGQNFEIIFVSADRSEESFKQYFSEMPWLAVPYTDEARRSR
LNRLYGIQGIPTLIMLDPQGEVITRQGRVEVLNDEDCREFPWHPKPVLELSDSNAAQLNEGPCLVLFVDSEDDGESEAAKQLIQPIAEKI

--------------------------------------------------------------
>In-frame_ENST00000291107_ENST00000336868_TCGA-OL-A66P-01A_ABR_chr17_953290_-_NXN_chr17_729318_length(transcript)=4296nt_BP=1712nt
TTCCTGTCTGCCCTCCGCGGGCTCCGGCTGCCATGGAGGAGGAAGAGGAGGCGATAGGCTTGCTGGACAAGGTTCTGGAGGACGAAGATG
TGTTTCTCCTGGAGGAGTGCGAGCTGGGAACCCCGACCAGCCCCGGCTCAGGGTCCCCCTTCCTGGTGGCTGTGAAGGTGGAAGCAGGGA
AAGGCCTGGAGATGAGGAAGCTGGTTCTCTCGGGGTTCTTGGCCAGCGAAGAGATCTACATTAACCAGCTGGAAGCCCTGTTGCTGCCCA
TGAAACCCCTGAAGGCCACCGCCACCACCTCCCAGCCCGTGCTCACCATCCAGCAGATCGAGACCATCTTCTACAAGATCCAGGACATCT
ATGAGATCCACAAGGAGTTCTATGACAACCTGTGCCCCAAGGTGCAACAGTGGGACAGCCAGGTCACCATGGGCCACCTCTTCCAGAAGC
TGGCCAGCCAGCTCGGTGTGTACAAAGCGTTTGTCGATAACTATAAAGTCGCTCTGGAGACAGCTGAGAAGTGCAGCCAGTCCAACAACC
AGTTCCAGAAGATCTCAGAGGAACTCAAAGTGAAAGGTCCCAAGGACTCCAAGGACAGCCACACGTCTGTCACCATGGAAGCTCTGCTCT
ACAAGCCCATTGACCGGGTCACTCGGAGCACCCTAGTCCTACACGACCTGCTGAAGCACACACCTGTGGACCACCCCGACTACCCGCTGC
TGCAGGATGCCCTCCGCATCTCCCAGAACTTCCTGTCCAGCATCAACGAGGACATCGACCCCCGCCGGACTGCAGTGACAACGCCCAAGG
GGGAGACGCGACAGCTGGTGAAGGACGGCTTCCTGGTGGAAGTGTCAGAGAGCTCCCGGAAGCTGCGGCACGTCTTCCTCTTTACAGATG
TCCTACTGTGTGCCAAGCTGAAGAAGACCTCTGCAGGGAAGCACCAGCAGTATGACTGTAAGTGGTACATCCCCCTGGCCGACCTGGTGT
TTCCATCCCCCGAGGAGTCTGAGGCCAGCCCCCAGGTGCACCCCTTCCCAGACCATGAGCTGGAGGACATGAAGATGAAGATCTCTGCCC
TCAAGAGTGAAATCCAGAAGGAGAAAGCCAACAAAGGCCAGAGCCGGGCCATCGAGCGCCTGAAGAAGAAGATGTTTGAGAATGAGTTCC
TGCTGCTGCTCAACTCCCCCACAATCCCGTTCAGGATCCACAATCGGAATGGAAAGAGTTACCTGTTCCTACTGTCCTCGGACTACGAGA
GGTCAGAGTGGAGAGAAGCAATTCAGAAACTACAGAAGAAGGATCTCCAGGCCTTTGTCCTGAGCTCAGTGGAGCTCCAGGTGCTCACAG
GATCCTGTTTCAAGCTTAGGACTGTACACAACATTCCTGTCACCAGCAATAAAGACGACGATGAGTCTCCAGGACTCTATGGCTTCCTTC
ATGTCATCGTCCACTCTGCCAAGGGATTTAAGCAATCAGCCAACCTGTACTGTACCCTGGAGGTGGATTCCTTCGGCTATTTTGTCAGCA
AAGCCAAAACCAGGGTGTTCCGGGACACAGCGGAGCCCAAGTGGGATGAGGAGTTTGAGATCGAGCTGGAGGGCTCCCAGTCCCTGAGGA
TCCTGTGCTATGAGAAGTGCTATGACAAGACCAAGGTCAACAAGGACAACAATGAGATCGTGGACAAGATCATGGGCAAAGGACAGATCC
AGCTCAAACTTTGGAACAAATACCGAATTTCCAACATTCCATCACTAATATTCCTCGACGCCACCACTGGGAAGGTTGTGTGCAGGAACG
GGCTGCTGGTGATCCGAGATGACCCAGAAGGTCTGGAGTTCCCCTGGGGACCGAAACCCTTCAGGGAAGTCATTGCAGGGCCCTTGCTTA
GAAACAATGGGCAGTCTCTGGAGAGCAGCAGCCTGGAGGGGTCTCACGTGGGCGTCTATTTCTCCGCACATTGGTGTCCGCCCTGCCGAA
GCCTCACCCGGGTCCTGGTGGAATCCTACCGGAAGATCAAGGAGGCAGGCCAGAACTTCGAGATCATCTTCGTTAGTGCAGACAGGTCGG
AGGAGTCCTTCAAACAGTACTTCAGTGAGATGCCCTGGCTCGCCGTCCCCTACACGGATGAGGCCCGGCGGTCGCGCCTCAACCGGCTGT
ACGGAATCCAAGGCATCCCCACGCTCATCATGCTGGACCCGCAGGGCGAGGTGATCACGCGGCAGGGGCGGGTGGAGGTGCTGAACGACG
AGGACTGCCGGGAGTTCCCCTGGCACCCCAAGCCCGTGCTGGAGCTCTCCGACTCCAACGCCGCGCAGCTTAACGAGGGCCCCTGCCTCG
TCCTTTTTGTAGATTCTGAGGATGACGGAGAGTCCGAGGCGGCCAAGCAGCTGATTCAGCCGATAGCTGAGAAAATCATTGCCAAGTACA
AAGCCAAAGAGGAGGAGGCACCCCTTCTGTTCTTCGTAGCCGGGGAGGATGACATGACTGACTCCCTGCGAGATTACACCAACCTGCCTG
AGGCTGCCCCTTTGCTCACCATCCTGGACATGTCAGCCCGGGCCAAGTACGTGATGGACGTGGAGGAGATCACCCCCGCCATCGTGGAGG
CCTTTGTGAATGACTTCCTAGCAGAGAAGCTCAAACCGGAGCCCATCTAGCGTGGCTCCGGCCTCCTGAGACGTTATTTAAAACTCAGCC
TTCTCCTCCTCCCCCTCCTTCCTTCCGCCCTTGGACTTACCCAGCGTGCCCCGAATCCCACCACCCAAGTGTCCAGCCTCTCTGTGGTGC
CTTGTTTCTGCAGTAAACTCCTCAGCCAGCACCCTGGGGTGTGGAATCAGCAGCGGCAGAGTCCACCGTGTTTGGAGACTCTGTTTGGGA
GCACGGGATGGCCGGGGGCCCGGCCAGAGCGGGGCTGCATGGCTTTCGCAAAGTCACTAGCTTTTGGTGAAGGATCTGCCAGGGTGTCCT
GGGCAGAGTGAGCGTGGAGGGCCGGTGGGTCCCGCTCGGGCTCTGACTCTGACGTCGGCACACACGGCCCCGGACGGCCAGAGGGGAACC
GCCGGGTGACACCTGCGTGGAGGCTGAGCTGAGAAAGGGCCTCCGCTTAGAGCTGCGGGTGAGGACGTCCTTTTCTAAGCAACACAGTCT
TCCTCGGTCTGAGAGAAAAGCAGCCCACTCTTGTGTTCTCAGGCAGGGGATCTCCAAATGCAAAAGGAAGCTTGTAGAGGTTTTTTGGGT
GAGAAGAAAAATGTAGCTAAGGTAATGGTTCATATCATACAAACAGCTCCCACGATCCTGAAATTCTGTTAACGAATCCTTCTCTTTGGA
CATCTTCCCAAGAAACTTAGCCCTGAGTCCTAGGAGGAGCACCTCTGCACCAGCACGGACCTCTCGCTCCACCCAGCTCTGTGCCCAAGG
CCCCTGATCTCTGCTGAGGTGCCCACACCCACGTTCGATCACCCCTGCCATTCCCTTTTATTTTCTTTTTTTTGAGATGGAGTCTTGCTC
TGTCGCCCAGGCTGGAGTGCAGTGGCACCATCTTGGCTCACTTCAACCTCCGCCCCCAAGGTTCAAGTGATTCTCCTGCCTCAGCCTCCC
GAGTAGCTGGGATTACAGGCACCCGCCACCGTACCTGGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTGGCCAGGCTG
GTCTCGAACTCCTGACCTCAGGTGATCCACCCGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCGCCGTGCCCGGCCCCCTT
TTCTTTTCAAAGCAGAACTACAAAGATGAGAAATTACCAGAAGCCTCGCCTTTTCCTAAGCACCAGCGGAAGGAGCTGTGCCCCGGGATG
GAGTGAGGGTGGAGGGCGCGTCAGCCACGGGTGGGCCTTGTGTCGCCTTGTATCGGCCCAGGTAGGTTGTTGGCCTCTTACTTGGGCTGA
CCTGACCCCCGAAAGAGAAACAGACAACTCTGTTCTCAGGATTGGGGATGGACGGCTTCGGCCAAGCGTTTTAGCCTCATTCACTCAGGC
CCCACTCAGCACTCTGCCAGCCAAGACCATTGATTTGGAAAATCCGGTCCCCACCCGCTAATGAGCTGTTGACACTGTTGTTCCTTGCTG
AATTGGATTGTTGACTTGTAGTTCAGAGGCGTACAACTAGTTGGCGATTAGACTTGTTATGTGATGTTACCAGCCTGAAATGCGATCACC

>In-frame_ENST00000291107_ENST00000336868_TCGA-OL-A66P-01A_ABR_chr17_953290_-_NXN_chr17_729318_length(amino acids)=875AA_start in transcript=32_stop in transcript=2659
MEEEEEAIGLLDKVLEDEDVFLLEECELGTPTSPGSGSPFLVAVKVEAGKGLEMRKLVLSGFLASEEIYINQLEALLLPMKPLKATATTS
QPVLTIQQIETIFYKIQDIYEIHKEFYDNLCPKVQQWDSQVTMGHLFQKLASQLGVYKAFVDNYKVALETAEKCSQSNNQFQKISEELKV
KGPKDSKDSHTSVTMEALLYKPIDRVTRSTLVLHDLLKHTPVDHPDYPLLQDALRISQNFLSSINEDIDPRRTAVTTPKGETRQLVKDGF
LVEVSESSRKLRHVFLFTDVLLCAKLKKTSAGKHQQYDCKWYIPLADLVFPSPEESEASPQVHPFPDHELEDMKMKISALKSEIQKEKAN
KGQSRAIERLKKKMFENEFLLLLNSPTIPFRIHNRNGKSYLFLLSSDYERSEWREAIQKLQKKDLQAFVLSSVELQVLTGSCFKLRTVHN
IPVTSNKDDDESPGLYGFLHVIVHSAKGFKQSANLYCTLEVDSFGYFVSKAKTRVFRDTAEPKWDEEFEIELEGSQSLRILCYEKCYDKT
KVNKDNNEIVDKIMGKGQIQLKLWNKYRISNIPSLIFLDATTGKVVCRNGLLVIRDDPEGLEFPWGPKPFREVIAGPLLRNNGQSLESSS
LEGSHVGVYFSAHWCPPCRSLTRVLVESYRKIKEAGQNFEIIFVSADRSEESFKQYFSEMPWLAVPYTDEARRSRLNRLYGIQGIPTLIM
LDPQGEVITRQGRVEVLNDEDCREFPWHPKPVLELSDSNAAQLNEGPCLVLFVDSEDDGESEAAKQLIQPIAEKIIAKYKAKEEEAPLLF

--------------------------------------------------------------
>In-frame_ENST00000536794_ENST00000336868_TCGA-OL-A66P-01A_ABR_chr17_953290_-_NXN_chr17_729318_length(transcript)=4008nt_BP=1424nt
AGCCTCGTGCCCAGGCAGCCAGCCAGCTACAAACGTGCTCCTCTTTAGGATGCCAGCAGGCTGCTGGCTCCCTCCCTCCCTACCCCTCCT
CCCCTTCCCCTTCCCTCCTCTCCTCGCCACGCGCCTCCCTCCCCTCCCCCTTGCTGGAAGAGCACTCCGGAGCGGCTGCCCGATGCTGGA
GTCCGTGCGGCAGCATCAGCAAGGTGGCTGAGTGGCCGGGCTGCTGGTGGGCGCCGGGGAGCCTGGAGCGATGGCTGCACGCTCCCGCCG
CGGGGACAGAGGCTGCCATGGAGATTCTCCTCATTATTCGCTTCTGCTGTAACTGCACCTATGCTCTGCTCTACAAGCCCATTGACCGGG
TCACTCGGAGCACCCTAGTCCTACACGACCTGCTGAAGCACACACCTGTGGACCACCCCGACTACCCGCTGCTGCAGGATGCCCTCCGCA
TCTCCCAGAACTTCCTGTCCAGCATCAACGAGGACATCGACCCCCGCCGGACTGCAGTGACAACGCCCAAGGGGGAGACGCGACAGCTGG
TGAAGGACGGCTTCCTGGTGGAAGTGTCAGAGAGCTCCCGGAAGCTGCGGCACGTCTTCCTCTTTACAGATGTCCTACTGTGTGCCAAGC
TGAAGAAGACCTCTGCAGGGAAGCACCAGCAGTATGACTGTAAGTGGTACATCCCCCTGGCCGACCTGGTGTTTCCATCCCCCGAGGAGT
CTGAGGCCAGCCCCCAGGTGCACCCCTTCCCAGACCATGAGCTGGAGGACATGAAGATGAAGATCTCTGCCCTCAAGAGTGAAATCCAGA
AGGAGAAAGCCAACAAAGGCCAGAGCCGGGCCATCGAGCGCCTGAAGAAGAAGATGTTTGAGAATGAGTTCCTGCTGCTGCTCAACTCCC
CCACAATCCCGTTCAGGATCCACAATCGGAATGGAAAGAGTTACCTGTTCCTACTGTCCTCGGACTACGAGAGGTCAGAGTGGAGAGAAG
CAATTCAGAAACTACAGAAGAAGGATCTCCAGGCCTTTGTCCTGAGCTCAGTGGAGCTCCAGGTGCTCACAGGATCCTGTTTCAAGCTTA
GGACTGTACACAACATTCCTGTCACCAGCAATAAAGACGACGATGAGTCTCCAGGACTCTATGGCTTCCTTCATGTCATCGTCCACTCTG
CCAAGGGATTTAAGCAATCAGCCAACCTGTACTGTACCCTGGAGGTGGATTCCTTCGGCTATTTTGTCAGCAAAGCCAAAACCAGGGTGT
TCCGGGACACAGCGGAGCCCAAGTGGGATGAGGAGTTTGAGATCGAGCTGGAGGGCTCCCAGTCCCTGAGGATCCTGTGCTATGAGAAGT
GCTATGACAAGACCAAGGTCAACAAGGACAACAATGAGATCGTGGACAAGATCATGGGCAAAGGACAGATCCAGCTCAAACTTTGGAACA
AATACCGAATTTCCAACATTCCATCACTAATATTCCTCGACGCCACCACTGGGAAGGTTGTGTGCAGGAACGGGCTGCTGGTGATCCGAG
ATGACCCAGAAGGTCTGGAGTTCCCCTGGGGACCGAAACCCTTCAGGGAAGTCATTGCAGGGCCCTTGCTTAGAAACAATGGGCAGTCTC
TGGAGAGCAGCAGCCTGGAGGGGTCTCACGTGGGCGTCTATTTCTCCGCACATTGGTGTCCGCCCTGCCGAAGCCTCACCCGGGTCCTGG
TGGAATCCTACCGGAAGATCAAGGAGGCAGGCCAGAACTTCGAGATCATCTTCGTTAGTGCAGACAGGTCGGAGGAGTCCTTCAAACAGT
ACTTCAGTGAGATGCCCTGGCTCGCCGTCCCCTACACGGATGAGGCCCGGCGGTCGCGCCTCAACCGGCTGTACGGAATCCAAGGCATCC
CCACGCTCATCATGCTGGACCCGCAGGGCGAGGTGATCACGCGGCAGGGGCGGGTGGAGGTGCTGAACGACGAGGACTGCCGGGAGTTCC
CCTGGCACCCCAAGCCCGTGCTGGAGCTCTCCGACTCCAACGCCGCGCAGCTTAACGAGGGCCCCTGCCTCGTCCTTTTTGTAGATTCTG
AGGATGACGGAGAGTCCGAGGCGGCCAAGCAGCTGATTCAGCCGATAGCTGAGAAAATCATTGCCAAGTACAAAGCCAAAGAGGAGGAGG
CACCCCTTCTGTTCTTCGTAGCCGGGGAGGATGACATGACTGACTCCCTGCGAGATTACACCAACCTGCCTGAGGCTGCCCCTTTGCTCA
CCATCCTGGACATGTCAGCCCGGGCCAAGTACGTGATGGACGTGGAGGAGATCACCCCCGCCATCGTGGAGGCCTTTGTGAATGACTTCC
TAGCAGAGAAGCTCAAACCGGAGCCCATCTAGCGTGGCTCCGGCCTCCTGAGACGTTATTTAAAACTCAGCCTTCTCCTCCTCCCCCTCC
TTCCTTCCGCCCTTGGACTTACCCAGCGTGCCCCGAATCCCACCACCCAAGTGTCCAGCCTCTCTGTGGTGCCTTGTTTCTGCAGTAAAC
TCCTCAGCCAGCACCCTGGGGTGTGGAATCAGCAGCGGCAGAGTCCACCGTGTTTGGAGACTCTGTTTGGGAGCACGGGATGGCCGGGGG
CCCGGCCAGAGCGGGGCTGCATGGCTTTCGCAAAGTCACTAGCTTTTGGTGAAGGATCTGCCAGGGTGTCCTGGGCAGAGTGAGCGTGGA
GGGCCGGTGGGTCCCGCTCGGGCTCTGACTCTGACGTCGGCACACACGGCCCCGGACGGCCAGAGGGGAACCGCCGGGTGACACCTGCGT
GGAGGCTGAGCTGAGAAAGGGCCTCCGCTTAGAGCTGCGGGTGAGGACGTCCTTTTCTAAGCAACACAGTCTTCCTCGGTCTGAGAGAAA
AGCAGCCCACTCTTGTGTTCTCAGGCAGGGGATCTCCAAATGCAAAAGGAAGCTTGTAGAGGTTTTTTGGGTGAGAAGAAAAATGTAGCT
AAGGTAATGGTTCATATCATACAAACAGCTCCCACGATCCTGAAATTCTGTTAACGAATCCTTCTCTTTGGACATCTTCCCAAGAAACTT
AGCCCTGAGTCCTAGGAGGAGCACCTCTGCACCAGCACGGACCTCTCGCTCCACCCAGCTCTGTGCCCAAGGCCCCTGATCTCTGCTGAG
GTGCCCACACCCACGTTCGATCACCCCTGCCATTCCCTTTTATTTTCTTTTTTTTGAGATGGAGTCTTGCTCTGTCGCCCAGGCTGGAGT
GCAGTGGCACCATCTTGGCTCACTTCAACCTCCGCCCCCAAGGTTCAAGTGATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAG
GCACCCGCCACCGTACCTGGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACTCCTGACCT
CAGGTGATCCACCCGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCGCCGTGCCCGGCCCCCTTTTCTTTTCAAAGCAGAAC
TACAAAGATGAGAAATTACCAGAAGCCTCGCCTTTTCCTAAGCACCAGCGGAAGGAGCTGTGCCCCGGGATGGAGTGAGGGTGGAGGGCG
CGTCAGCCACGGGTGGGCCTTGTGTCGCCTTGTATCGGCCCAGGTAGGTTGTTGGCCTCTTACTTGGGCTGACCTGACCCCCGAAAGAGA
AACAGACAACTCTGTTCTCAGGATTGGGGATGGACGGCTTCGGCCAAGCGTTTTAGCCTCATTCACTCAGGCCCCACTCAGCACTCTGCC
AGCCAAGACCATTGATTTGGAAAATCCGGTCCCCACCCGCTAATGAGCTGTTGACACTGTTGTTCCTTGCTGAATTGGATTGTTGACTTG
TAGTTCAGAGGCGTACAACTAGTTGGCGATTAGACTTGTTATGTGATGTTACCAGCCTGAAATGCGATCACCCCGTAGGAAATAAAGCAG

>In-frame_ENST00000536794_ENST00000336868_TCGA-OL-A66P-01A_ABR_chr17_953290_-_NXN_chr17_729318_length(amino acids)=743AA_start in transcript=140_stop in transcript=2371
MLEEHSGAAARCWSPCGSISKVAEWPGCWWAPGSLERWLHAPAAGTEAAMEILLIIRFCCNCTYALLYKPIDRVTRSTLVLHDLLKHTPV
DHPDYPLLQDALRISQNFLSSINEDIDPRRTAVTTPKGETRQLVKDGFLVEVSESSRKLRHVFLFTDVLLCAKLKKTSAGKHQQYDCKWY
IPLADLVFPSPEESEASPQVHPFPDHELEDMKMKISALKSEIQKEKANKGQSRAIERLKKKMFENEFLLLLNSPTIPFRIHNRNGKSYLF
LLSSDYERSEWREAIQKLQKKDLQAFVLSSVELQVLTGSCFKLRTVHNIPVTSNKDDDESPGLYGFLHVIVHSAKGFKQSANLYCTLEVD
SFGYFVSKAKTRVFRDTAEPKWDEEFEIELEGSQSLRILCYEKCYDKTKVNKDNNEIVDKIMGKGQIQLKLWNKYRISNIPSLIFLDATT
GKVVCRNGLLVIRDDPEGLEFPWGPKPFREVIAGPLLRNNGQSLESSSLEGSHVGVYFSAHWCPPCRSLTRVLVESYRKIKEAGQNFEII
FVSADRSEESFKQYFSEMPWLAVPYTDEARRSRLNRLYGIQGIPTLIMLDPQGEVITRQGRVEVLNDEDCREFPWHPKPVLELSDSNAAQ
LNEGPCLVLFVDSEDDGESEAAKQLIQPIAEKIIAKYKAKEEEAPLLFFVAGEDDMTDSLRDYTNLPEAAPLLTILDMSARAKYVMDVEE

--------------------------------------------------------------
>In-frame_ENST00000302538_ENST00000336868_TCGA-91-6836-01A_ABR_chr17_1082961_-_NXN_chr17_729318_length(transcript)=2792nt_BP=208nt
GCCCCGCGCTCCTCCCGGGGACCTGGTTCCCGGCCTCCTCGCCCCTCCGCGCTCGCAACTTCGGCCTCCCCCGGCTCCCGCCCGCTCTCC
CTCCTTTGTTGCGCGATGAGGGTCGGGTTTCGGATCTGACCGAGCCGCCGCCGCGGGATGGAGCCGCTCAGCCACCGGGGCCTGCCGCGC
CTGTCCTGGATCGACACCCTCTACAGCACTCAAACTTTGGAACAAATACCGAATTTCCAACATTCCATCACTAATATTCCTCGACGCCAC
CACTGGGAAGGTTGTGTGCAGGAACGGGCTGCTGGTGATCCGAGATGACCCAGAAGGTCTGGAGTTCCCCTGGGGACCGAAACCCTTCAG
GGAAGTCATTGCAGGGCCCTTGCTTAGAAACAATGGGCAGTCTCTGGAGAGCAGCAGCCTGGAGGGGTCTCACGTGGGCGTCTATTTCTC
CGCACATTGGTGTCCGCCCTGCCGAAGCCTCACCCGGGTCCTGGTGGAATCCTACCGGAAGATCAAGGAGGCAGGCCAGAACTTCGAGAT
CATCTTCGTTAGTGCAGACAGGTCGGAGGAGTCCTTCAAACAGTACTTCAGTGAGATGCCCTGGCTCGCCGTCCCCTACACGGATGAGGC
CCGGCGGTCGCGCCTCAACCGGCTGTACGGAATCCAAGGCATCCCCACGCTCATCATGCTGGACCCGCAGGGCGAGGTGATCACGCGGCA
GGGGCGGGTGGAGGTGCTGAACGACGAGGACTGCCGGGAGTTCCCCTGGCACCCCAAGCCCGTGCTGGAGCTCTCCGACTCCAACGCCGC
GCAGCTTAACGAGGGCCCCTGCCTCGTCCTTTTTGTAGATTCTGAGGATGACGGAGAGTCCGAGGCGGCCAAGCAGCTGATTCAGCCGAT
AGCTGAGAAAATCATTGCCAAGTACAAAGCCAAAGAGGAGGAGGCACCCCTTCTGTTCTTCGTAGCCGGGGAGGATGACATGACTGACTC
CCTGCGAGATTACACCAACCTGCCTGAGGCTGCCCCTTTGCTCACCATCCTGGACATGTCAGCCCGGGCCAAGTACGTGATGGACGTGGA
GGAGATCACCCCCGCCATCGTGGAGGCCTTTGTGAATGACTTCCTAGCAGAGAAGCTCAAACCGGAGCCCATCTAGCGTGGCTCCGGCCT
CCTGAGACGTTATTTAAAACTCAGCCTTCTCCTCCTCCCCCTCCTTCCTTCCGCCCTTGGACTTACCCAGCGTGCCCCGAATCCCACCAC
CCAAGTGTCCAGCCTCTCTGTGGTGCCTTGTTTCTGCAGTAAACTCCTCAGCCAGCACCCTGGGGTGTGGAATCAGCAGCGGCAGAGTCC
ACCGTGTTTGGAGACTCTGTTTGGGAGCACGGGATGGCCGGGGGCCCGGCCAGAGCGGGGCTGCATGGCTTTCGCAAAGTCACTAGCTTT
TGGTGAAGGATCTGCCAGGGTGTCCTGGGCAGAGTGAGCGTGGAGGGCCGGTGGGTCCCGCTCGGGCTCTGACTCTGACGTCGGCACACA
CGGCCCCGGACGGCCAGAGGGGAACCGCCGGGTGACACCTGCGTGGAGGCTGAGCTGAGAAAGGGCCTCCGCTTAGAGCTGCGGGTGAGG
ACGTCCTTTTCTAAGCAACACAGTCTTCCTCGGTCTGAGAGAAAAGCAGCCCACTCTTGTGTTCTCAGGCAGGGGATCTCCAAATGCAAA
AGGAAGCTTGTAGAGGTTTTTTGGGTGAGAAGAAAAATGTAGCTAAGGTAATGGTTCATATCATACAAACAGCTCCCACGATCCTGAAAT
TCTGTTAACGAATCCTTCTCTTTGGACATCTTCCCAAGAAACTTAGCCCTGAGTCCTAGGAGGAGCACCTCTGCACCAGCACGGACCTCT
CGCTCCACCCAGCTCTGTGCCCAAGGCCCCTGATCTCTGCTGAGGTGCCCACACCCACGTTCGATCACCCCTGCCATTCCCTTTTATTTT
CTTTTTTTTGAGATGGAGTCTTGCTCTGTCGCCCAGGCTGGAGTGCAGTGGCACCATCTTGGCTCACTTCAACCTCCGCCCCCAAGGTTC
AAGTGATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGCACCCGCCACCGTACCTGGCTAATTTTTGTATTTTTAGTAGAGAT
GGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACTCCTGACCTCAGGTGATCCACCCGCCTCGGCCTCCCAAAGTGCTGGGATTACAGG
CGTGAGCCGCCGTGCCCGGCCCCCTTTTCTTTTCAAAGCAGAACTACAAAGATGAGAAATTACCAGAAGCCTCGCCTTTTCCTAAGCACC
AGCGGAAGGAGCTGTGCCCCGGGATGGAGTGAGGGTGGAGGGCGCGTCAGCCACGGGTGGGCCTTGTGTCGCCTTGTATCGGCCCAGGTA
GGTTGTTGGCCTCTTACTTGGGCTGACCTGACCCCCGAAAGAGAAACAGACAACTCTGTTCTCAGGATTGGGGATGGACGGCTTCGGCCA
AGCGTTTTAGCCTCATTCACTCAGGCCCCACTCAGCACTCTGCCAGCCAAGACCATTGATTTGGAAAATCCGGTCCCCACCCGCTAATGA
GCTGTTGACACTGTTGTTCCTTGCTGAATTGGATTGTTGACTTGTAGTTCAGAGGCGTACAACTAGTTGGCGATTAGACTTGTTATGTGA
TGTTACCAGCCTGAAATGCGATCACCCCGTAGGAAATAAAGCAGGCATCTCTGGACCTCATCCACCCTGGGCCTCTGCTGTCCTTGATCA

>In-frame_ENST00000302538_ENST00000336868_TCGA-91-6836-01A_ABR_chr17_1082961_-_NXN_chr17_729318_length(amino acids)=285AA_start in transcript=298_stop in transcript=1155
MLVIRDDPEGLEFPWGPKPFREVIAGPLLRNNGQSLESSSLEGSHVGVYFSAHWCPPCRSLTRVLVESYRKIKEAGQNFEIIFVSADRSE
ESFKQYFSEMPWLAVPYTDEARRSRLNRLYGIQGIPTLIMLDPQGEVITRQGRVEVLNDEDCREFPWHPKPVLELSDSNAAQLNEGPCLV
LFVDSEDDGESEAAKQLIQPIAEKIIAKYKAKEEEAPLLFFVAGEDDMTDSLRDYTNLPEAAPLLTILDMSARAKYVMDVEEITPAIVEA

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ABR-NXN


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ABR-NXN


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ABR-NXN


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneABRC0033578Prostatic Neoplasms1CTD_human
HgeneABRC0376358Malignant neoplasm of prostate1CTD_human
TgeneNXNC0009402Colorectal Carcinoma1CTD_human
TgeneNXNC0009404Colorectal Neoplasms1CTD_human
TgeneNXNC1849334Robinow syndrome, autosomal recessive1ORPHANET