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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:PRKAR1B-GNA12 (FusionGDB2 ID:68241) |
Fusion Gene Summary for PRKAR1B-GNA12 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: PRKAR1B-GNA12 | Fusion gene ID: 68241 | Hgene | Tgene | Gene symbol | PRKAR1B | GNA12 | Gene ID | 5575 | 2768 |
| Gene name | protein kinase cAMP-dependent type I regulatory subunit beta | G protein subunit alpha 12 | |
| Synonyms | PRKAR1 | NNX3|RMP|gep | |
| Cytomap | 7p22.3 | 7p22.3-p22.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | cAMP-dependent protein kinase type I-beta regulatory subunitprotein kinase, cAMP-dependent, regulatory subunit type I betaprotein kinase, cAMP-dependent, regulatory, type I, beta | guanine nucleotide-binding protein subunit alpha-12WUGSC:H_GS165O14.2g alpha-12guanine nucleotide binding protein (G protein) alpha 12 | |
| Modification date | 20200327 | 20200313 | |
| UniProtAcc | . | Q03113 | |
| Ensembl transtripts involved in fusion gene | ENST00000544935, ENST00000537384, ENST00000406797, ENST00000403562, ENST00000360274, ENST00000488474, | ENST00000275364, ENST00000544127, ENST00000491117, ENST00000407904, ENST00000407653, ENST00000396960, | |
| Fusion gene scores | * DoF score | 6 X 6 X 5=180 | 7 X 6 X 4=168 |
| # samples | 7 | 9 | |
| ** MAII score | log2(7/180*10)=-1.36257007938471 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(9/168*10)=-0.900464326449086 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: PRKAR1B [Title/Abstract] AND GNA12 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | PRKAR1B(645830)-GNA12(2773135), # samples:2 | ||
| Anticipated loss of major functional domain due to fusion event. | PRKAR1B-GNA12 seems lost the major protein functional domain in Hgene partner, which is a cell metabolism gene due to the frame-shifted ORF. PRKAR1B-GNA12 seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | PRKAR1B | GO:2000480 | negative regulation of cAMP-dependent protein kinase activity | 21812984 |
| Fusion gene breakpoints across PRKAR1B (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
| Fusion gene breakpoints across GNA12 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | OV | TCGA-24-1847-01A | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| ChimerDB4 | OV | TCGA-24-1847 | PRKAR1B | chr7 | 645829 | - | GNA12 | chr7 | 2773135 | - |
| ChimerDB4 | OV | TCGA-24-1847-01A | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
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Fusion Gene ORF analysis for PRKAR1B-GNA12 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000544935 | ENST00000275364 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-intron | ENST00000544935 | ENST00000544127 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-5UTR | ENST00000544935 | ENST00000491117 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-5UTR | ENST00000544935 | ENST00000407904 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-5UTR | ENST00000544935 | ENST00000407653 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-5UTR | ENST00000544935 | ENST00000396960 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| Frame-shift | ENST00000537384 | ENST00000275364 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-intron | ENST00000537384 | ENST00000544127 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-5UTR | ENST00000537384 | ENST00000491117 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-5UTR | ENST00000537384 | ENST00000407904 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-5UTR | ENST00000537384 | ENST00000407653 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-5UTR | ENST00000537384 | ENST00000396960 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| In-frame | ENST00000406797 | ENST00000275364 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-intron | ENST00000406797 | ENST00000544127 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-5UTR | ENST00000406797 | ENST00000491117 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-5UTR | ENST00000406797 | ENST00000407904 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-5UTR | ENST00000406797 | ENST00000407653 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-5UTR | ENST00000406797 | ENST00000396960 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| In-frame | ENST00000403562 | ENST00000275364 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-intron | ENST00000403562 | ENST00000544127 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-5UTR | ENST00000403562 | ENST00000491117 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-5UTR | ENST00000403562 | ENST00000407904 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-5UTR | ENST00000403562 | ENST00000407653 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-5UTR | ENST00000403562 | ENST00000396960 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| Frame-shift | ENST00000360274 | ENST00000275364 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-intron | ENST00000360274 | ENST00000544127 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-5UTR | ENST00000360274 | ENST00000491117 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-5UTR | ENST00000360274 | ENST00000407904 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-5UTR | ENST00000360274 | ENST00000407653 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-5UTR | ENST00000360274 | ENST00000396960 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| intron-3CDS | ENST00000488474 | ENST00000275364 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| intron-intron | ENST00000488474 | ENST00000544127 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| intron-5UTR | ENST00000488474 | ENST00000491117 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| intron-5UTR | ENST00000488474 | ENST00000407904 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| intron-5UTR | ENST00000488474 | ENST00000407653 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| intron-5UTR | ENST00000488474 | ENST00000396960 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| In-frame | ENST00000544935 | ENST00000275364 | PRKAR1B | chr7 | 645829 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-intron | ENST00000544935 | ENST00000544127 | PRKAR1B | chr7 | 645829 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-5UTR | ENST00000544935 | ENST00000491117 | PRKAR1B | chr7 | 645829 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-5UTR | ENST00000544935 | ENST00000407904 | PRKAR1B | chr7 | 645829 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-5UTR | ENST00000544935 | ENST00000407653 | PRKAR1B | chr7 | 645829 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-5UTR | ENST00000544935 | ENST00000396960 | PRKAR1B | chr7 | 645829 | - | GNA12 | chr7 | 2773135 | - |
| Frame-shift | ENST00000537384 | ENST00000275364 | PRKAR1B | chr7 | 645829 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-intron | ENST00000537384 | ENST00000544127 | PRKAR1B | chr7 | 645829 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-5UTR | ENST00000537384 | ENST00000491117 | PRKAR1B | chr7 | 645829 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-5UTR | ENST00000537384 | ENST00000407904 | PRKAR1B | chr7 | 645829 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-5UTR | ENST00000537384 | ENST00000407653 | PRKAR1B | chr7 | 645829 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-5UTR | ENST00000537384 | ENST00000396960 | PRKAR1B | chr7 | 645829 | - | GNA12 | chr7 | 2773135 | - |
| In-frame | ENST00000406797 | ENST00000275364 | PRKAR1B | chr7 | 645829 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-intron | ENST00000406797 | ENST00000544127 | PRKAR1B | chr7 | 645829 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-5UTR | ENST00000406797 | ENST00000491117 | PRKAR1B | chr7 | 645829 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-5UTR | ENST00000406797 | ENST00000407904 | PRKAR1B | chr7 | 645829 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-5UTR | ENST00000406797 | ENST00000407653 | PRKAR1B | chr7 | 645829 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-5UTR | ENST00000406797 | ENST00000396960 | PRKAR1B | chr7 | 645829 | - | GNA12 | chr7 | 2773135 | - |
| In-frame | ENST00000403562 | ENST00000275364 | PRKAR1B | chr7 | 645829 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-intron | ENST00000403562 | ENST00000544127 | PRKAR1B | chr7 | 645829 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-5UTR | ENST00000403562 | ENST00000491117 | PRKAR1B | chr7 | 645829 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-5UTR | ENST00000403562 | ENST00000407904 | PRKAR1B | chr7 | 645829 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-5UTR | ENST00000403562 | ENST00000407653 | PRKAR1B | chr7 | 645829 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-5UTR | ENST00000403562 | ENST00000396960 | PRKAR1B | chr7 | 645829 | - | GNA12 | chr7 | 2773135 | - |
| Frame-shift | ENST00000360274 | ENST00000275364 | PRKAR1B | chr7 | 645829 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-intron | ENST00000360274 | ENST00000544127 | PRKAR1B | chr7 | 645829 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-5UTR | ENST00000360274 | ENST00000491117 | PRKAR1B | chr7 | 645829 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-5UTR | ENST00000360274 | ENST00000407904 | PRKAR1B | chr7 | 645829 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-5UTR | ENST00000360274 | ENST00000407653 | PRKAR1B | chr7 | 645829 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-5UTR | ENST00000360274 | ENST00000396960 | PRKAR1B | chr7 | 645829 | - | GNA12 | chr7 | 2773135 | - |
| intron-3CDS | ENST00000488474 | ENST00000275364 | PRKAR1B | chr7 | 645829 | - | GNA12 | chr7 | 2773135 | - |
| intron-intron | ENST00000488474 | ENST00000544127 | PRKAR1B | chr7 | 645829 | - | GNA12 | chr7 | 2773135 | - |
| intron-5UTR | ENST00000488474 | ENST00000491117 | PRKAR1B | chr7 | 645829 | - | GNA12 | chr7 | 2773135 | - |
| intron-5UTR | ENST00000488474 | ENST00000407904 | PRKAR1B | chr7 | 645829 | - | GNA12 | chr7 | 2773135 | - |
| intron-5UTR | ENST00000488474 | ENST00000407653 | PRKAR1B | chr7 | 645829 | - | GNA12 | chr7 | 2773135 | - |
| intron-5UTR | ENST00000488474 | ENST00000396960 | PRKAR1B | chr7 | 645829 | - | GNA12 | chr7 | 2773135 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000544935 | PRKAR1B | chr7 | 645830 | - | ENST00000275364 | GNA12 | chr7 | 2773135 | - | 4354 | 664 | 115 | 1284 | 389 |
| ENST00000406797 | PRKAR1B | chr7 | 645830 | - | ENST00000275364 | GNA12 | chr7 | 2773135 | - | 4414 | 724 | 136 | 1344 | 402 |
| ENST00000403562 | PRKAR1B | chr7 | 645830 | - | ENST00000275364 | GNA12 | chr7 | 2773135 | - | 4322 | 632 | 83 | 1252 | 389 |
| ENST00000544935 | PRKAR1B | chr7 | 645829 | - | ENST00000275364 | GNA12 | chr7 | 2773135 | - | 4354 | 664 | 115 | 1284 | 389 |
| ENST00000406797 | PRKAR1B | chr7 | 645829 | - | ENST00000275364 | GNA12 | chr7 | 2773135 | - | 4414 | 724 | 136 | 1344 | 402 |
| ENST00000403562 | PRKAR1B | chr7 | 645829 | - | ENST00000275364 | GNA12 | chr7 | 2773135 | - | 4322 | 632 | 83 | 1252 | 389 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000544935 | ENST00000275364 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - | 0.001604088 | 0.99839586 |
| ENST00000406797 | ENST00000275364 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - | 0.001671049 | 0.998329 |
| ENST00000403562 | ENST00000275364 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - | 0.001614158 | 0.9983859 |
| ENST00000544935 | ENST00000275364 | PRKAR1B | chr7 | 645829 | - | GNA12 | chr7 | 2773135 | - | 0.001604088 | 0.99839586 |
| ENST00000406797 | ENST00000275364 | PRKAR1B | chr7 | 645829 | - | GNA12 | chr7 | 2773135 | - | 0.001671049 | 0.998329 |
| ENST00000403562 | ENST00000275364 | PRKAR1B | chr7 | 645829 | - | GNA12 | chr7 | 2773135 | - | 0.001614158 | 0.9983859 |
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Fusion Genomic Features for PRKAR1B-GNA12 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for PRKAR1B-GNA12 |
| Go to FGviewer for the breakpoints of chr7:645830-chr7:2773135 - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | GNA12 |
| FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes. | FUNCTION: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems (PubMed:22609986, PubMed:15525651, PubMed:15240885, PubMed:17565996, PubMed:12515866, PubMed:16787920, PubMed:16705036, PubMed:23762476, PubMed:27084452). Activates effector molecule RhoA by binding and activating RhoGEFs (ARHGEF12/LARG) (PubMed:15240885, PubMed:12515866, PubMed:16202387). GNA12-dependent Rho signaling subsequently regulates transcription factor AP-1 (activating protein-1) (By similarity). GNA12-dependent Rho signaling also regulates protein phosphatese 2A activation causing dephosphorylation of its target proteins (PubMed:15525651, PubMed:17565996). Promotes tumor cell invasion and metastasis by activating RhoA/ROCK signaling pathway and up-regulating proinflammatory cytokine production (PubMed:23762476, PubMed:16787920, PubMed:16705036, PubMed:27084452). Inhibits CDH1-mediated cell adhesion in process independent from Rho activation (PubMed:11976333, PubMed:16787920). Together with NAPA promotes CDH5 localization to plasma membrane (PubMed:15980433). May play a role in the control of cell migration through the TOR signaling cascade (PubMed:22609986). {ECO:0000250|UniProtKB:P27600, ECO:0000269|PubMed:11976333, ECO:0000269|PubMed:12515866, ECO:0000269|PubMed:15240885, ECO:0000269|PubMed:15525651, ECO:0000269|PubMed:15980433, ECO:0000269|PubMed:16705036, ECO:0000269|PubMed:16787920, ECO:0000269|PubMed:17565996, ECO:0000269|PubMed:22609986, ECO:0000269|PubMed:23762476, ECO:0000269|PubMed:27084452}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | PRKAR1B | chr7:645829 | chr7:2773135 | ENST00000360274 | - | 6 | 11 | 96_100 | 183.0 | 382.0 | Motif | Note=Pseudophosphorylation motif |
| Hgene | PRKAR1B | chr7:645829 | chr7:2773135 | ENST00000403562 | - | 6 | 11 | 96_100 | 183.0 | 382.0 | Motif | Note=Pseudophosphorylation motif |
| Hgene | PRKAR1B | chr7:645829 | chr7:2773135 | ENST00000406797 | - | 6 | 11 | 96_100 | 183.0 | 382.0 | Motif | Note=Pseudophosphorylation motif |
| Hgene | PRKAR1B | chr7:645829 | chr7:2773135 | ENST00000537384 | - | 6 | 11 | 96_100 | 183.0 | 382.0 | Motif | Note=Pseudophosphorylation motif |
| Hgene | PRKAR1B | chr7:645829 | chr7:2773135 | ENST00000544935 | - | 6 | 11 | 96_100 | 183.0 | 382.0 | Motif | Note=Pseudophosphorylation motif |
| Hgene | PRKAR1B | chr7:645830 | chr7:2773135 | ENST00000360274 | - | 6 | 11 | 96_100 | 183.0 | 382.0 | Motif | Note=Pseudophosphorylation motif |
| Hgene | PRKAR1B | chr7:645830 | chr7:2773135 | ENST00000403562 | - | 6 | 11 | 96_100 | 183.0 | 382.0 | Motif | Note=Pseudophosphorylation motif |
| Hgene | PRKAR1B | chr7:645830 | chr7:2773135 | ENST00000406797 | - | 6 | 11 | 96_100 | 183.0 | 382.0 | Motif | Note=Pseudophosphorylation motif |
| Hgene | PRKAR1B | chr7:645830 | chr7:2773135 | ENST00000537384 | - | 6 | 11 | 96_100 | 183.0 | 382.0 | Motif | Note=Pseudophosphorylation motif |
| Hgene | PRKAR1B | chr7:645830 | chr7:2773135 | ENST00000544935 | - | 6 | 11 | 96_100 | 183.0 | 382.0 | Motif | Note=Pseudophosphorylation motif |
| Hgene | PRKAR1B | chr7:645829 | chr7:2773135 | ENST00000360274 | - | 6 | 11 | 2_136 | 183.0 | 382.0 | Region | Note=Dimerization and phosphorylation |
| Hgene | PRKAR1B | chr7:645829 | chr7:2773135 | ENST00000403562 | - | 6 | 11 | 2_136 | 183.0 | 382.0 | Region | Note=Dimerization and phosphorylation |
| Hgene | PRKAR1B | chr7:645829 | chr7:2773135 | ENST00000406797 | - | 6 | 11 | 2_136 | 183.0 | 382.0 | Region | Note=Dimerization and phosphorylation |
| Hgene | PRKAR1B | chr7:645829 | chr7:2773135 | ENST00000537384 | - | 6 | 11 | 2_136 | 183.0 | 382.0 | Region | Note=Dimerization and phosphorylation |
| Hgene | PRKAR1B | chr7:645829 | chr7:2773135 | ENST00000544935 | - | 6 | 11 | 2_136 | 183.0 | 382.0 | Region | Note=Dimerization and phosphorylation |
| Hgene | PRKAR1B | chr7:645830 | chr7:2773135 | ENST00000360274 | - | 6 | 11 | 2_136 | 183.0 | 382.0 | Region | Note=Dimerization and phosphorylation |
| Hgene | PRKAR1B | chr7:645830 | chr7:2773135 | ENST00000403562 | - | 6 | 11 | 2_136 | 183.0 | 382.0 | Region | Note=Dimerization and phosphorylation |
| Hgene | PRKAR1B | chr7:645830 | chr7:2773135 | ENST00000406797 | - | 6 | 11 | 2_136 | 183.0 | 382.0 | Region | Note=Dimerization and phosphorylation |
| Hgene | PRKAR1B | chr7:645830 | chr7:2773135 | ENST00000537384 | - | 6 | 11 | 2_136 | 183.0 | 382.0 | Region | Note=Dimerization and phosphorylation |
| Hgene | PRKAR1B | chr7:645830 | chr7:2773135 | ENST00000544935 | - | 6 | 11 | 2_136 | 183.0 | 382.0 | Region | Note=Dimerization and phosphorylation |
| Tgene | GNA12 | chr7:645829 | chr7:2773135 | ENST00000275364 | 1 | 4 | 202_205 | 175.0 | 382.0 | Nucleotide binding | GTP | |
| Tgene | GNA12 | chr7:645829 | chr7:2773135 | ENST00000275364 | 1 | 4 | 296_299 | 175.0 | 382.0 | Nucleotide binding | GTP | |
| Tgene | GNA12 | chr7:645830 | chr7:2773135 | ENST00000275364 | 1 | 4 | 202_205 | 175.0 | 382.0 | Nucleotide binding | GTP | |
| Tgene | GNA12 | chr7:645830 | chr7:2773135 | ENST00000275364 | 1 | 4 | 296_299 | 175.0 | 382.0 | Nucleotide binding | GTP | |
| Tgene | GNA12 | chr7:645829 | chr7:2773135 | ENST00000275364 | 1 | 4 | 200_208 | 175.0 | 382.0 | Region | G2 motif | |
| Tgene | GNA12 | chr7:645829 | chr7:2773135 | ENST00000275364 | 1 | 4 | 223_232 | 175.0 | 382.0 | Region | G3 motif | |
| Tgene | GNA12 | chr7:645829 | chr7:2773135 | ENST00000275364 | 1 | 4 | 292_299 | 175.0 | 382.0 | Region | G4 motif | |
| Tgene | GNA12 | chr7:645829 | chr7:2773135 | ENST00000275364 | 1 | 4 | 351_356 | 175.0 | 382.0 | Region | G5 motif | |
| Tgene | GNA12 | chr7:645830 | chr7:2773135 | ENST00000275364 | 1 | 4 | 200_208 | 175.0 | 382.0 | Region | G2 motif | |
| Tgene | GNA12 | chr7:645830 | chr7:2773135 | ENST00000275364 | 1 | 4 | 223_232 | 175.0 | 382.0 | Region | G3 motif | |
| Tgene | GNA12 | chr7:645830 | chr7:2773135 | ENST00000275364 | 1 | 4 | 292_299 | 175.0 | 382.0 | Region | G4 motif | |
| Tgene | GNA12 | chr7:645830 | chr7:2773135 | ENST00000275364 | 1 | 4 | 351_356 | 175.0 | 382.0 | Region | G5 motif |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | PRKAR1B | chr7:645829 | chr7:2773135 | ENST00000360274 | - | 6 | 11 | 137_254 | 183.0 | 382.0 | Nucleotide binding | Note=cAMP 1 |
| Hgene | PRKAR1B | chr7:645829 | chr7:2773135 | ENST00000360274 | - | 6 | 11 | 255_381 | 183.0 | 382.0 | Nucleotide binding | Note=cAMP 2 |
| Hgene | PRKAR1B | chr7:645829 | chr7:2773135 | ENST00000403562 | - | 6 | 11 | 137_254 | 183.0 | 382.0 | Nucleotide binding | Note=cAMP 1 |
| Hgene | PRKAR1B | chr7:645829 | chr7:2773135 | ENST00000403562 | - | 6 | 11 | 255_381 | 183.0 | 382.0 | Nucleotide binding | Note=cAMP 2 |
| Hgene | PRKAR1B | chr7:645829 | chr7:2773135 | ENST00000406797 | - | 6 | 11 | 137_254 | 183.0 | 382.0 | Nucleotide binding | Note=cAMP 1 |
| Hgene | PRKAR1B | chr7:645829 | chr7:2773135 | ENST00000406797 | - | 6 | 11 | 255_381 | 183.0 | 382.0 | Nucleotide binding | Note=cAMP 2 |
| Hgene | PRKAR1B | chr7:645829 | chr7:2773135 | ENST00000537384 | - | 6 | 11 | 137_254 | 183.0 | 382.0 | Nucleotide binding | Note=cAMP 1 |
| Hgene | PRKAR1B | chr7:645829 | chr7:2773135 | ENST00000537384 | - | 6 | 11 | 255_381 | 183.0 | 382.0 | Nucleotide binding | Note=cAMP 2 |
| Hgene | PRKAR1B | chr7:645829 | chr7:2773135 | ENST00000544935 | - | 6 | 11 | 137_254 | 183.0 | 382.0 | Nucleotide binding | Note=cAMP 1 |
| Hgene | PRKAR1B | chr7:645829 | chr7:2773135 | ENST00000544935 | - | 6 | 11 | 255_381 | 183.0 | 382.0 | Nucleotide binding | Note=cAMP 2 |
| Hgene | PRKAR1B | chr7:645830 | chr7:2773135 | ENST00000360274 | - | 6 | 11 | 137_254 | 183.0 | 382.0 | Nucleotide binding | Note=cAMP 1 |
| Hgene | PRKAR1B | chr7:645830 | chr7:2773135 | ENST00000360274 | - | 6 | 11 | 255_381 | 183.0 | 382.0 | Nucleotide binding | Note=cAMP 2 |
| Hgene | PRKAR1B | chr7:645830 | chr7:2773135 | ENST00000403562 | - | 6 | 11 | 137_254 | 183.0 | 382.0 | Nucleotide binding | Note=cAMP 1 |
| Hgene | PRKAR1B | chr7:645830 | chr7:2773135 | ENST00000403562 | - | 6 | 11 | 255_381 | 183.0 | 382.0 | Nucleotide binding | Note=cAMP 2 |
| Hgene | PRKAR1B | chr7:645830 | chr7:2773135 | ENST00000406797 | - | 6 | 11 | 137_254 | 183.0 | 382.0 | Nucleotide binding | Note=cAMP 1 |
| Hgene | PRKAR1B | chr7:645830 | chr7:2773135 | ENST00000406797 | - | 6 | 11 | 255_381 | 183.0 | 382.0 | Nucleotide binding | Note=cAMP 2 |
| Hgene | PRKAR1B | chr7:645830 | chr7:2773135 | ENST00000537384 | - | 6 | 11 | 137_254 | 183.0 | 382.0 | Nucleotide binding | Note=cAMP 1 |
| Hgene | PRKAR1B | chr7:645830 | chr7:2773135 | ENST00000537384 | - | 6 | 11 | 255_381 | 183.0 | 382.0 | Nucleotide binding | Note=cAMP 2 |
| Hgene | PRKAR1B | chr7:645830 | chr7:2773135 | ENST00000544935 | - | 6 | 11 | 137_254 | 183.0 | 382.0 | Nucleotide binding | Note=cAMP 1 |
| Hgene | PRKAR1B | chr7:645830 | chr7:2773135 | ENST00000544935 | - | 6 | 11 | 255_381 | 183.0 | 382.0 | Nucleotide binding | Note=cAMP 2 |
| Tgene | GNA12 | chr7:645829 | chr7:2773135 | ENST00000275364 | 1 | 4 | 56_381 | 175.0 | 382.0 | Domain | G-alpha | |
| Tgene | GNA12 | chr7:645830 | chr7:2773135 | ENST00000275364 | 1 | 4 | 56_381 | 175.0 | 382.0 | Domain | G-alpha | |
| Tgene | GNA12 | chr7:645829 | chr7:2773135 | ENST00000275364 | 1 | 4 | 67_72 | 175.0 | 382.0 | Nucleotide binding | GTP | |
| Tgene | GNA12 | chr7:645830 | chr7:2773135 | ENST00000275364 | 1 | 4 | 67_72 | 175.0 | 382.0 | Nucleotide binding | GTP | |
| Tgene | GNA12 | chr7:645829 | chr7:2773135 | ENST00000275364 | 1 | 4 | 59_72 | 175.0 | 382.0 | Region | G1 motif | |
| Tgene | GNA12 | chr7:645830 | chr7:2773135 | ENST00000275364 | 1 | 4 | 59_72 | 175.0 | 382.0 | Region | G1 motif |
Top |
Fusion Gene Sequence for PRKAR1B-GNA12 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >In-frame_ENST00000544935_ENST00000275364_TCGA-24-1847-01A_PRKAR1B_chr7_645830_-_GNA12_chr7_2773135_length(transcript)=4354nt_BP=664nt CTCTGGCCGCTAAGGCAGAGTGAGACCCCAGGGAACGGGCGTGCTTGCTGGGTACCGGGTGTCCTGCAGAGGCAGGGATGTGATCCCCTA GGTGAAGGAAGCAGCCACCCTCGCCATGGCCTCCCCGCCCGCCTGCCCCTCGGAGGAGGACGAGAGCCTGAAGGGCTGTGAGCTGTACGT GCAGCTGCACGGGATCCAGCAGGTCCTCAAAGACTGTATCGTCCACCTCTGCATCTCCAAGCCCGAACGCCCCATGAAGTTCCTCCGGGA GCACTTCGAGAAGCTGGAGAAGGAAGAAAACAGGCAGATTTTGGCGCGGCAAAAGTCAAACTCACAGTCGGACTCCCATGATGAGGAGGT GTCGCCCACCCCCCCGAACCCTGTGGTGAAGGCCCGCCGCCGGCGAGGAGGCGTGAGTGCCGAGGTGTACACCGAGGAGGACGCCGTGTC CTACGTCAGGAAGGTGATTCCCAAGGACTACAAAACCATGACTGCGCTGGCCAAGGCCATCTCCAAGAACGTGCTCTTCGCTCACCTGGA TGACAACGAGAGGAGTGACATATTCGATGCCATGTTCCCTGTCACTCACATCGCTGGGGAGACTGTTATACAGCAAGGGAATGAAGGAGA CAACTTCTATGTCGTTGATCAAGGGGAAGTGGATGGGGAGTCGGTGAAGTACTTCCTGGACAACTTGGACCGGATCGGCCAGCTGAATTA CTTTCCTAGTAAGCAAGATATCCTGCTGGCTAGGAAAGCCACCAAGGGAATTGTGGAGCATGACTTCGTTATTAAGAAGATCCCCTTTAA GATGGTGGATGTGGGCGGCCAGCGGTCCCAGCGCCAGAAGTGGTTCCAGTGCTTCGACGGGATCACGTCCATCCTGTTCATGGTCTCCTC CAGCGAGTACGACCAGGTCCTCATGGAGGACAGGCGCACCAACCGGCTGGTGGAGTCCATGAACATCTTCGAGACCATCGTCAACAACAA GCTCTTCTTCAACGTCTCCATCATTCTCTTCCTCAACAAGATGGACCTCCTGGTGGAGAAGGTGAAGACCGTGAGCATCAAGAAGCACTT CCCGGACTTCAGGGGCGACCCGCACAGGCTGGAGGACGTCCAGCGCTACCTGGTCCAGTGCTTCGACAGGAAGAGACGGAACCGCAGCAA GCCACTCTTCCACCACTTCACCACCGCCATCGACACCGAGAACGTCCGCTTCGTGTTCCATGCTGTGAAAGACACCATCCTGCAGGAGAA CCTGAAGGACATCATGCTGCAGTGAGCGAGGAAGCCCCGGGGTTTGTCGTCGTTGAGCAGCCCCCACGGCTGTCGGTCAGACTCTTGGGT GTGTGTTGTCTGTGTGGTCCTTGAGTGGGTTTCTCGGATCCGTGCCCTGGAATACCTGGCTCAGGAATGCTGTCAGACCAGCCAGCCAGC GAGCTCTAGGCAAAAGGACATGGAAACTGTCACGTTAGCTACTGAATCCTGGGGGCGAGTGAAACTACTGAAAATCCGAGTGATGATGTT GTGAATACGGAACACCTAATCACACAGCTTGCTTTGCTTTTACAGAAACGTTCCTCTTTTTCTGACGCAGTTTAATTGAGGACCGTGTTG TGTGTGTATGTGTGTACACACGCTCTGTCTTTAATGACAGAAACACAAAAACCAGCTGGCCTTGCAGACGGCTTTTCTAACTCACAAGTC TTCCCTGAGACAGACTAACCTGAAAGCTTTGCCTAACAGTAGCTTGTAGAGATCCAGTGCACGCCGATGCTGCTAAACTCAGTGCCTGAG CCCGGCCCTGCAGCCCCAGCCGCAGTGTCTGAAGGCCACCTCCCAAAGGGAGCACGTTGCCTTTTCAAACTCCCGTGCCGATTTCCTAAG AGCCCCTAGTCCAAGCCTCTCAGATGAAGCTGAGGAGCCGTGCCTAGGATCCCTTCCCAGCTCTGAGGACGGGCTGCAGAGCTCTGCAGG TGTGGATTCACCTTACGCCCCTACAGCAGGCTCAGCCCTTCCCACCCTGCCCCATGCCCAGCAGCACAACACGGAGTGAGACAGGATGCC CACGGTGACTGCCGCTCCGTCCGTGCACACACAGCGGTGCTCTTCTCCCCTTAGCCACCCACTGCCCAACCCAACGGCAAAGACACAGAA ACCAGGTCCCCTTGCAGACGGCTCTCCCATCTTCCTGCAAGTCATCTGCTCACACACAGTTGGCAGCACATAGCGTTTCCTTCTTTCAGA AACATTCCTCTTCTGGGGCTTCAGAAAGCTGGCAAGGCCACTAGCAGAGCTTTTGTTAATGCCCCAGCTGCTTGGCGAGCTAACAGCTGA CCTTTCGGGAAGCCCACAGACGCTGGAGGAATCTTGAGTTTCTCCAAACTGCCGCTCCACCAGTGCCTTTGGACAGCCGTGCCTGTTCGC CGCTCTCCCTAAGTCTGATTCTCATCGAGGCCCCTCGCTTCTATGACTGTGCTTGCAGAAGAGTAAACACTCTCGGATGCCGCTGTCCTG GGGGAGCCCGCGGGAGCCTGTGAATGTTGATACGAGCTGGCCAGTCCTGGGCCCAGCTCACTTGTCCAGCTACCTGCCAGGTGGCTTTCA CTGTGTTTAAAATACATTGCATTCCAAGCTGGTCCCCTCTGTGTATCACTCTACTGAGAAATCCTGCCTAGTGTGTTTTGGGATGTGTCC TAGCATTTACAAGAAAATGAAAAGCGTCCTCTTAATTGGCACCCGAATGTTGCTGTGGCTCAGTCACATATCCCAGGGCCCTCGTCCCGA GGCCGTGCTGCCCCGAGCCCCGAGCCCCTCTGCAGCTCACCCTTGGCTTGTTTTCCGCAAACCCGGTAAACGCAAGCCCTTGGGGCAGAT GCAGAAGCAGAAGAGGGAGGGGAAACCTGCCTCTGGGTCACCCTGTTAGCACAGCGTTCTCATCGGGAGACAGCATGGAACTCTCTCTCG CAGTGCTCGAGGCTGTGTGTCAGTGTTTGCTGGGCTTGTGGCTCCTTTTTTGGCTGGATAAAGAAGTCGCTGTTTTTGTACTGCTTCTGT GGCTCTTCACAGACCTCACGGATGTGACCGGAGATGAGTGCCGATGACCACGTTTTAAAGGAGAAAGAGAGCTCCTGGTGGGGCCCTCGG GGTGGTCTCAGGTCCCATTTGCAGTCTGCAACAGTGACGCGCAGCCCGGTCCGGAGCGTGGTGAGCTTTGTTTGCCTTCTGGGTCAGCTT TCGCTGTGTCTCCTGTGTGTGTTAGAATCCAGAGCCCAGAGGAAGTGCAAGCGGGTCCTCCGCCAACGGGGAGAGCCTCTTCGCGGCGCT GTTGGCGACAGCAGCGCTGTGATTCGCGTAGCAGGGGAGTTGTTTGAAACACCTTCCTGAGTAGTCCGGCCTTGTCAATGAGTGCTTGTT TTCCTTTAAACAGTCTGACATATTTACTCGTCACTTTCAAACCAGAAGCATGAGAGGAAGGAGATATTGTGGGGTCCGTTTAACTCGATA GAAAGCGCAGGGGGATGGCCCCCGGCGCGGGCTCTTGACCCGCTCAGCGCTGACCCCACCGCCCTGGCCGAGGCACTTGGCCTTGCTGAG CTGGACTTCCTCCTCCTCCTCCTCATGACCGGGGTGAATTAGAACGTTTTTAAAGACACCCCCTTCCAAATTCTGTAACACATTGTAATT GGAGAAGAAGGAAACTCTGCAAGGCTAAACTGTCATTCACAACTTGGCTACACATAGACTCTAGTCAGTTTTGTCTCCAGAACCTTAGGC TTTTGTATTTTTTAATTTTAATTTCACTGTTAATCCTTATTGTCTTTTTTATTAAGATGTTGGAAAAGCAGGAGGTAGTTGTGCCTCAAT TATTGCAAAAATGTAACAATAAAGTTCCTCAAAATAAGATCTGTTCCTCATAGCTATACTGTGTACACATAAGACGCATATAGGGTTTTA CTGAAATCTATTTTTAACTCTTATGTTCGTAGAGAAATTGTTTCAAGGATTTTGAGTCATAGGTCTGTAATTTATAGAGATCTCTAGAAT TCTTATTGTAATTTTCCTACTTCTTTGATAAAAGAAAAATAAGTCAGATTGTTAACTCCAAGATTGAAAAAAAAAACTCTTGAAAGAAGA TTATTAGTTGTAACTAATTTAGGGGTTCTGGGCACAGACATCTAACCTGGTATTGTAAGGCAGAGGCTCCCATTGGAATGGTAGTGGTCC GGGTCAGTTGTTCATGGTGTAAGCTTTGCACAGTGTATTAACATTGGGAGGGTCTGGCTTGAAAATTTGGCCACCCTCAGCCTCTGAATG >In-frame_ENST00000544935_ENST00000275364_TCGA-24-1847-01A_PRKAR1B_chr7_645830_-_GNA12_chr7_2773135_length(amino acids)=389AA_start in transcript=115_stop in transcript=1284 MASPPACPSEEDESLKGCELYVQLHGIQQVLKDCIVHLCISKPERPMKFLREHFEKLEKEENRQILARQKSNSQSDSHDEEVSPTPPNPV VKARRRRGGVSAEVYTEEDAVSYVRKVIPKDYKTMTALAKAISKNVLFAHLDDNERSDIFDAMFPVTHIAGETVIQQGNEGDNFYVVDQG EVDGESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLM EDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRLEDVQRYLVQCFDRKRRNRSKPLFHHFTT -------------------------------------------------------------- >In-frame_ENST00000406797_ENST00000275364_TCGA-24-1847-01A_PRKAR1B_chr7_645830_-_GNA12_chr7_2773135_length(transcript)=4414nt_BP=724nt AGTTTCTGCCGCCGCCACCCTGGCAGGATGGGGCAACGGTGTGCGGTAGGAGGATGAGGTTGATTCCCTTTCCTGCAGGGCTGGGCTTGT GGGTTAGGACCGTCACCAAGAGGCTCCTCCTAGGCCTCCGTGACCTCTGGATCCCCAAGAAAGGAAGGAAGCAGCCACCCTCGCCATGGC CTCCCCGCCCGCCTGCCCCTCGGAGGAGGACGAGAGCCTGAAGGGCTGTGAGCTGTACGTGCAGCTGCACGGGATCCAGCAGGTCCTCAA AGACTGTATCGTCCACCTCTGCATCTCCAAGCCCGAACGCCCCATGAAGTTCCTCCGGGAGCACTTCGAGAAGCTGGAGAAGGAAGAAAA CAGGCAGATTTTGGCGCGGCAAAAGTCAAACTCACAGTCGGACTCCCATGATGAGGAGGTGTCGCCCACCCCCCCGAACCCTGTGGTGAA GGCCCGCCGCCGGCGAGGAGGCGTGAGTGCCGAGGTGTACACCGAGGAGGACGCCGTGTCCTACGTCAGGAAGGTGATTCCCAAGGACTA CAAAACCATGACTGCGCTGGCCAAGGCCATCTCCAAGAACGTGCTCTTCGCTCACCTGGATGACAACGAGAGGAGTGACATATTCGATGC CATGTTCCCTGTCACTCACATCGCTGGGGAGACTGTTATACAGCAAGGGAATGAAGGAGACAACTTCTATGTCGTTGATCAAGGGGAAGT GGATGGGGAGTCGGTGAAGTACTTCCTGGACAACTTGGACCGGATCGGCCAGCTGAATTACTTTCCTAGTAAGCAAGATATCCTGCTGGC TAGGAAAGCCACCAAGGGAATTGTGGAGCATGACTTCGTTATTAAGAAGATCCCCTTTAAGATGGTGGATGTGGGCGGCCAGCGGTCCCA GCGCCAGAAGTGGTTCCAGTGCTTCGACGGGATCACGTCCATCCTGTTCATGGTCTCCTCCAGCGAGTACGACCAGGTCCTCATGGAGGA CAGGCGCACCAACCGGCTGGTGGAGTCCATGAACATCTTCGAGACCATCGTCAACAACAAGCTCTTCTTCAACGTCTCCATCATTCTCTT CCTCAACAAGATGGACCTCCTGGTGGAGAAGGTGAAGACCGTGAGCATCAAGAAGCACTTCCCGGACTTCAGGGGCGACCCGCACAGGCT GGAGGACGTCCAGCGCTACCTGGTCCAGTGCTTCGACAGGAAGAGACGGAACCGCAGCAAGCCACTCTTCCACCACTTCACCACCGCCAT CGACACCGAGAACGTCCGCTTCGTGTTCCATGCTGTGAAAGACACCATCCTGCAGGAGAACCTGAAGGACATCATGCTGCAGTGAGCGAG GAAGCCCCGGGGTTTGTCGTCGTTGAGCAGCCCCCACGGCTGTCGGTCAGACTCTTGGGTGTGTGTTGTCTGTGTGGTCCTTGAGTGGGT TTCTCGGATCCGTGCCCTGGAATACCTGGCTCAGGAATGCTGTCAGACCAGCCAGCCAGCGAGCTCTAGGCAAAAGGACATGGAAACTGT CACGTTAGCTACTGAATCCTGGGGGCGAGTGAAACTACTGAAAATCCGAGTGATGATGTTGTGAATACGGAACACCTAATCACACAGCTT GCTTTGCTTTTACAGAAACGTTCCTCTTTTTCTGACGCAGTTTAATTGAGGACCGTGTTGTGTGTGTATGTGTGTACACACGCTCTGTCT TTAATGACAGAAACACAAAAACCAGCTGGCCTTGCAGACGGCTTTTCTAACTCACAAGTCTTCCCTGAGACAGACTAACCTGAAAGCTTT GCCTAACAGTAGCTTGTAGAGATCCAGTGCACGCCGATGCTGCTAAACTCAGTGCCTGAGCCCGGCCCTGCAGCCCCAGCCGCAGTGTCT GAAGGCCACCTCCCAAAGGGAGCACGTTGCCTTTTCAAACTCCCGTGCCGATTTCCTAAGAGCCCCTAGTCCAAGCCTCTCAGATGAAGC TGAGGAGCCGTGCCTAGGATCCCTTCCCAGCTCTGAGGACGGGCTGCAGAGCTCTGCAGGTGTGGATTCACCTTACGCCCCTACAGCAGG CTCAGCCCTTCCCACCCTGCCCCATGCCCAGCAGCACAACACGGAGTGAGACAGGATGCCCACGGTGACTGCCGCTCCGTCCGTGCACAC ACAGCGGTGCTCTTCTCCCCTTAGCCACCCACTGCCCAACCCAACGGCAAAGACACAGAAACCAGGTCCCCTTGCAGACGGCTCTCCCAT CTTCCTGCAAGTCATCTGCTCACACACAGTTGGCAGCACATAGCGTTTCCTTCTTTCAGAAACATTCCTCTTCTGGGGCTTCAGAAAGCT GGCAAGGCCACTAGCAGAGCTTTTGTTAATGCCCCAGCTGCTTGGCGAGCTAACAGCTGACCTTTCGGGAAGCCCACAGACGCTGGAGGA ATCTTGAGTTTCTCCAAACTGCCGCTCCACCAGTGCCTTTGGACAGCCGTGCCTGTTCGCCGCTCTCCCTAAGTCTGATTCTCATCGAGG CCCCTCGCTTCTATGACTGTGCTTGCAGAAGAGTAAACACTCTCGGATGCCGCTGTCCTGGGGGAGCCCGCGGGAGCCTGTGAATGTTGA TACGAGCTGGCCAGTCCTGGGCCCAGCTCACTTGTCCAGCTACCTGCCAGGTGGCTTTCACTGTGTTTAAAATACATTGCATTCCAAGCT GGTCCCCTCTGTGTATCACTCTACTGAGAAATCCTGCCTAGTGTGTTTTGGGATGTGTCCTAGCATTTACAAGAAAATGAAAAGCGTCCT CTTAATTGGCACCCGAATGTTGCTGTGGCTCAGTCACATATCCCAGGGCCCTCGTCCCGAGGCCGTGCTGCCCCGAGCCCCGAGCCCCTC TGCAGCTCACCCTTGGCTTGTTTTCCGCAAACCCGGTAAACGCAAGCCCTTGGGGCAGATGCAGAAGCAGAAGAGGGAGGGGAAACCTGC CTCTGGGTCACCCTGTTAGCACAGCGTTCTCATCGGGAGACAGCATGGAACTCTCTCTCGCAGTGCTCGAGGCTGTGTGTCAGTGTTTGC TGGGCTTGTGGCTCCTTTTTTGGCTGGATAAAGAAGTCGCTGTTTTTGTACTGCTTCTGTGGCTCTTCACAGACCTCACGGATGTGACCG GAGATGAGTGCCGATGACCACGTTTTAAAGGAGAAAGAGAGCTCCTGGTGGGGCCCTCGGGGTGGTCTCAGGTCCCATTTGCAGTCTGCA ACAGTGACGCGCAGCCCGGTCCGGAGCGTGGTGAGCTTTGTTTGCCTTCTGGGTCAGCTTTCGCTGTGTCTCCTGTGTGTGTTAGAATCC AGAGCCCAGAGGAAGTGCAAGCGGGTCCTCCGCCAACGGGGAGAGCCTCTTCGCGGCGCTGTTGGCGACAGCAGCGCTGTGATTCGCGTA GCAGGGGAGTTGTTTGAAACACCTTCCTGAGTAGTCCGGCCTTGTCAATGAGTGCTTGTTTTCCTTTAAACAGTCTGACATATTTACTCG TCACTTTCAAACCAGAAGCATGAGAGGAAGGAGATATTGTGGGGTCCGTTTAACTCGATAGAAAGCGCAGGGGGATGGCCCCCGGCGCGG GCTCTTGACCCGCTCAGCGCTGACCCCACCGCCCTGGCCGAGGCACTTGGCCTTGCTGAGCTGGACTTCCTCCTCCTCCTCCTCATGACC GGGGTGAATTAGAACGTTTTTAAAGACACCCCCTTCCAAATTCTGTAACACATTGTAATTGGAGAAGAAGGAAACTCTGCAAGGCTAAAC TGTCATTCACAACTTGGCTACACATAGACTCTAGTCAGTTTTGTCTCCAGAACCTTAGGCTTTTGTATTTTTTAATTTTAATTTCACTGT TAATCCTTATTGTCTTTTTTATTAAGATGTTGGAAAAGCAGGAGGTAGTTGTGCCTCAATTATTGCAAAAATGTAACAATAAAGTTCCTC AAAATAAGATCTGTTCCTCATAGCTATACTGTGTACACATAAGACGCATATAGGGTTTTACTGAAATCTATTTTTAACTCTTATGTTCGT AGAGAAATTGTTTCAAGGATTTTGAGTCATAGGTCTGTAATTTATAGAGATCTCTAGAATTCTTATTGTAATTTTCCTACTTCTTTGATA AAAGAAAAATAAGTCAGATTGTTAACTCCAAGATTGAAAAAAAAAACTCTTGAAAGAAGATTATTAGTTGTAACTAATTTAGGGGTTCTG GGCACAGACATCTAACCTGGTATTGTAAGGCAGAGGCTCCCATTGGAATGGTAGTGGTCCGGGTCAGTTGTTCATGGTGTAAGCTTTGCA CAGTGTATTAACATTGGGAGGGTCTGGCTTGAAAATTTGGCCACCCTCAGCCTCTGAATGTTTATTAAAATAAATTTAGTCTTTCTTTGC >In-frame_ENST00000406797_ENST00000275364_TCGA-24-1847-01A_PRKAR1B_chr7_645830_-_GNA12_chr7_2773135_length(amino acids)=402AA_start in transcript=136_stop in transcript=1344 MDPQERKEAATLAMASPPACPSEEDESLKGCELYVQLHGIQQVLKDCIVHLCISKPERPMKFLREHFEKLEKEENRQILARQKSNSQSDS HDEEVSPTPPNPVVKARRRRGGVSAEVYTEEDAVSYVRKVIPKDYKTMTALAKAISKNVLFAHLDDNERSDIFDAMFPVTHIAGETVIQQ GNEGDNFYVVDQGEVDGESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSIL FMVSSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRLEDVQRYLVQCFDRKR -------------------------------------------------------------- >In-frame_ENST00000403562_ENST00000275364_TCGA-24-1847-01A_PRKAR1B_chr7_645830_-_GNA12_chr7_2773135_length(transcript)=4322nt_BP=632nt GTGAGGGCCAAGCAGGAACAGGGGTCACGGGGCAAGGAGCACGTGGCAGCGCAGGAAACAGGAAGGAAGCAGCCACCCTCGCCATGGCCT CCCCGCCCGCCTGCCCCTCGGAGGAGGACGAGAGCCTGAAGGGCTGTGAGCTGTACGTGCAGCTGCACGGGATCCAGCAGGTCCTCAAAG ACTGTATCGTCCACCTCTGCATCTCCAAGCCCGAACGCCCCATGAAGTTCCTCCGGGAGCACTTCGAGAAGCTGGAGAAGGAAGAAAACA GGCAGATTTTGGCGCGGCAAAAGTCAAACTCACAGTCGGACTCCCATGATGAGGAGGTGTCGCCCACCCCCCCGAACCCTGTGGTGAAGG CCCGCCGCCGGCGAGGAGGCGTGAGTGCCGAGGTGTACACCGAGGAGGACGCCGTGTCCTACGTCAGGAAGGTGATTCCCAAGGACTACA AAACCATGACTGCGCTGGCCAAGGCCATCTCCAAGAACGTGCTCTTCGCTCACCTGGATGACAACGAGAGGAGTGACATATTCGATGCCA TGTTCCCTGTCACTCACATCGCTGGGGAGACTGTTATACAGCAAGGGAATGAAGGAGACAACTTCTATGTCGTTGATCAAGGGGAAGTGG ATGGGGAGTCGGTGAAGTACTTCCTGGACAACTTGGACCGGATCGGCCAGCTGAATTACTTTCCTAGTAAGCAAGATATCCTGCTGGCTA GGAAAGCCACCAAGGGAATTGTGGAGCATGACTTCGTTATTAAGAAGATCCCCTTTAAGATGGTGGATGTGGGCGGCCAGCGGTCCCAGC GCCAGAAGTGGTTCCAGTGCTTCGACGGGATCACGTCCATCCTGTTCATGGTCTCCTCCAGCGAGTACGACCAGGTCCTCATGGAGGACA GGCGCACCAACCGGCTGGTGGAGTCCATGAACATCTTCGAGACCATCGTCAACAACAAGCTCTTCTTCAACGTCTCCATCATTCTCTTCC TCAACAAGATGGACCTCCTGGTGGAGAAGGTGAAGACCGTGAGCATCAAGAAGCACTTCCCGGACTTCAGGGGCGACCCGCACAGGCTGG AGGACGTCCAGCGCTACCTGGTCCAGTGCTTCGACAGGAAGAGACGGAACCGCAGCAAGCCACTCTTCCACCACTTCACCACCGCCATCG ACACCGAGAACGTCCGCTTCGTGTTCCATGCTGTGAAAGACACCATCCTGCAGGAGAACCTGAAGGACATCATGCTGCAGTGAGCGAGGA AGCCCCGGGGTTTGTCGTCGTTGAGCAGCCCCCACGGCTGTCGGTCAGACTCTTGGGTGTGTGTTGTCTGTGTGGTCCTTGAGTGGGTTT CTCGGATCCGTGCCCTGGAATACCTGGCTCAGGAATGCTGTCAGACCAGCCAGCCAGCGAGCTCTAGGCAAAAGGACATGGAAACTGTCA CGTTAGCTACTGAATCCTGGGGGCGAGTGAAACTACTGAAAATCCGAGTGATGATGTTGTGAATACGGAACACCTAATCACACAGCTTGC TTTGCTTTTACAGAAACGTTCCTCTTTTTCTGACGCAGTTTAATTGAGGACCGTGTTGTGTGTGTATGTGTGTACACACGCTCTGTCTTT AATGACAGAAACACAAAAACCAGCTGGCCTTGCAGACGGCTTTTCTAACTCACAAGTCTTCCCTGAGACAGACTAACCTGAAAGCTTTGC CTAACAGTAGCTTGTAGAGATCCAGTGCACGCCGATGCTGCTAAACTCAGTGCCTGAGCCCGGCCCTGCAGCCCCAGCCGCAGTGTCTGA AGGCCACCTCCCAAAGGGAGCACGTTGCCTTTTCAAACTCCCGTGCCGATTTCCTAAGAGCCCCTAGTCCAAGCCTCTCAGATGAAGCTG AGGAGCCGTGCCTAGGATCCCTTCCCAGCTCTGAGGACGGGCTGCAGAGCTCTGCAGGTGTGGATTCACCTTACGCCCCTACAGCAGGCT CAGCCCTTCCCACCCTGCCCCATGCCCAGCAGCACAACACGGAGTGAGACAGGATGCCCACGGTGACTGCCGCTCCGTCCGTGCACACAC AGCGGTGCTCTTCTCCCCTTAGCCACCCACTGCCCAACCCAACGGCAAAGACACAGAAACCAGGTCCCCTTGCAGACGGCTCTCCCATCT TCCTGCAAGTCATCTGCTCACACACAGTTGGCAGCACATAGCGTTTCCTTCTTTCAGAAACATTCCTCTTCTGGGGCTTCAGAAAGCTGG CAAGGCCACTAGCAGAGCTTTTGTTAATGCCCCAGCTGCTTGGCGAGCTAACAGCTGACCTTTCGGGAAGCCCACAGACGCTGGAGGAAT CTTGAGTTTCTCCAAACTGCCGCTCCACCAGTGCCTTTGGACAGCCGTGCCTGTTCGCCGCTCTCCCTAAGTCTGATTCTCATCGAGGCC CCTCGCTTCTATGACTGTGCTTGCAGAAGAGTAAACACTCTCGGATGCCGCTGTCCTGGGGGAGCCCGCGGGAGCCTGTGAATGTTGATA CGAGCTGGCCAGTCCTGGGCCCAGCTCACTTGTCCAGCTACCTGCCAGGTGGCTTTCACTGTGTTTAAAATACATTGCATTCCAAGCTGG TCCCCTCTGTGTATCACTCTACTGAGAAATCCTGCCTAGTGTGTTTTGGGATGTGTCCTAGCATTTACAAGAAAATGAAAAGCGTCCTCT TAATTGGCACCCGAATGTTGCTGTGGCTCAGTCACATATCCCAGGGCCCTCGTCCCGAGGCCGTGCTGCCCCGAGCCCCGAGCCCCTCTG CAGCTCACCCTTGGCTTGTTTTCCGCAAACCCGGTAAACGCAAGCCCTTGGGGCAGATGCAGAAGCAGAAGAGGGAGGGGAAACCTGCCT CTGGGTCACCCTGTTAGCACAGCGTTCTCATCGGGAGACAGCATGGAACTCTCTCTCGCAGTGCTCGAGGCTGTGTGTCAGTGTTTGCTG GGCTTGTGGCTCCTTTTTTGGCTGGATAAAGAAGTCGCTGTTTTTGTACTGCTTCTGTGGCTCTTCACAGACCTCACGGATGTGACCGGA GATGAGTGCCGATGACCACGTTTTAAAGGAGAAAGAGAGCTCCTGGTGGGGCCCTCGGGGTGGTCTCAGGTCCCATTTGCAGTCTGCAAC AGTGACGCGCAGCCCGGTCCGGAGCGTGGTGAGCTTTGTTTGCCTTCTGGGTCAGCTTTCGCTGTGTCTCCTGTGTGTGTTAGAATCCAG AGCCCAGAGGAAGTGCAAGCGGGTCCTCCGCCAACGGGGAGAGCCTCTTCGCGGCGCTGTTGGCGACAGCAGCGCTGTGATTCGCGTAGC AGGGGAGTTGTTTGAAACACCTTCCTGAGTAGTCCGGCCTTGTCAATGAGTGCTTGTTTTCCTTTAAACAGTCTGACATATTTACTCGTC ACTTTCAAACCAGAAGCATGAGAGGAAGGAGATATTGTGGGGTCCGTTTAACTCGATAGAAAGCGCAGGGGGATGGCCCCCGGCGCGGGC TCTTGACCCGCTCAGCGCTGACCCCACCGCCCTGGCCGAGGCACTTGGCCTTGCTGAGCTGGACTTCCTCCTCCTCCTCCTCATGACCGG GGTGAATTAGAACGTTTTTAAAGACACCCCCTTCCAAATTCTGTAACACATTGTAATTGGAGAAGAAGGAAACTCTGCAAGGCTAAACTG TCATTCACAACTTGGCTACACATAGACTCTAGTCAGTTTTGTCTCCAGAACCTTAGGCTTTTGTATTTTTTAATTTTAATTTCACTGTTA ATCCTTATTGTCTTTTTTATTAAGATGTTGGAAAAGCAGGAGGTAGTTGTGCCTCAATTATTGCAAAAATGTAACAATAAAGTTCCTCAA AATAAGATCTGTTCCTCATAGCTATACTGTGTACACATAAGACGCATATAGGGTTTTACTGAAATCTATTTTTAACTCTTATGTTCGTAG AGAAATTGTTTCAAGGATTTTGAGTCATAGGTCTGTAATTTATAGAGATCTCTAGAATTCTTATTGTAATTTTCCTACTTCTTTGATAAA AGAAAAATAAGTCAGATTGTTAACTCCAAGATTGAAAAAAAAAACTCTTGAAAGAAGATTATTAGTTGTAACTAATTTAGGGGTTCTGGG CACAGACATCTAACCTGGTATTGTAAGGCAGAGGCTCCCATTGGAATGGTAGTGGTCCGGGTCAGTTGTTCATGGTGTAAGCTTTGCACA GTGTATTAACATTGGGAGGGTCTGGCTTGAAAATTTGGCCACCCTCAGCCTCTGAATGTTTATTAAAATAAATTTAGTCTTTCTTTGCTT >In-frame_ENST00000403562_ENST00000275364_TCGA-24-1847-01A_PRKAR1B_chr7_645830_-_GNA12_chr7_2773135_length(amino acids)=389AA_start in transcript=83_stop in transcript=1252 MASPPACPSEEDESLKGCELYVQLHGIQQVLKDCIVHLCISKPERPMKFLREHFEKLEKEENRQILARQKSNSQSDSHDEEVSPTPPNPV VKARRRRGGVSAEVYTEEDAVSYVRKVIPKDYKTMTALAKAISKNVLFAHLDDNERSDIFDAMFPVTHIAGETVIQQGNEGDNFYVVDQG EVDGESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLM EDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRLEDVQRYLVQCFDRKRRNRSKPLFHHFTT -------------------------------------------------------------- >In-frame_ENST00000544935_ENST00000275364_TCGA-24-1847_PRKAR1B_chr7_645829_-_GNA12_chr7_2773135_length(transcript)=4354nt_BP=664nt CTCTGGCCGCTAAGGCAGAGTGAGACCCCAGGGAACGGGCGTGCTTGCTGGGTACCGGGTGTCCTGCAGAGGCAGGGATGTGATCCCCTA GGTGAAGGAAGCAGCCACCCTCGCCATGGCCTCCCCGCCCGCCTGCCCCTCGGAGGAGGACGAGAGCCTGAAGGGCTGTGAGCTGTACGT GCAGCTGCACGGGATCCAGCAGGTCCTCAAAGACTGTATCGTCCACCTCTGCATCTCCAAGCCCGAACGCCCCATGAAGTTCCTCCGGGA GCACTTCGAGAAGCTGGAGAAGGAAGAAAACAGGCAGATTTTGGCGCGGCAAAAGTCAAACTCACAGTCGGACTCCCATGATGAGGAGGT GTCGCCCACCCCCCCGAACCCTGTGGTGAAGGCCCGCCGCCGGCGAGGAGGCGTGAGTGCCGAGGTGTACACCGAGGAGGACGCCGTGTC CTACGTCAGGAAGGTGATTCCCAAGGACTACAAAACCATGACTGCGCTGGCCAAGGCCATCTCCAAGAACGTGCTCTTCGCTCACCTGGA TGACAACGAGAGGAGTGACATATTCGATGCCATGTTCCCTGTCACTCACATCGCTGGGGAGACTGTTATACAGCAAGGGAATGAAGGAGA CAACTTCTATGTCGTTGATCAAGGGGAAGTGGATGGGGAGTCGGTGAAGTACTTCCTGGACAACTTGGACCGGATCGGCCAGCTGAATTA CTTTCCTAGTAAGCAAGATATCCTGCTGGCTAGGAAAGCCACCAAGGGAATTGTGGAGCATGACTTCGTTATTAAGAAGATCCCCTTTAA GATGGTGGATGTGGGCGGCCAGCGGTCCCAGCGCCAGAAGTGGTTCCAGTGCTTCGACGGGATCACGTCCATCCTGTTCATGGTCTCCTC CAGCGAGTACGACCAGGTCCTCATGGAGGACAGGCGCACCAACCGGCTGGTGGAGTCCATGAACATCTTCGAGACCATCGTCAACAACAA GCTCTTCTTCAACGTCTCCATCATTCTCTTCCTCAACAAGATGGACCTCCTGGTGGAGAAGGTGAAGACCGTGAGCATCAAGAAGCACTT CCCGGACTTCAGGGGCGACCCGCACAGGCTGGAGGACGTCCAGCGCTACCTGGTCCAGTGCTTCGACAGGAAGAGACGGAACCGCAGCAA GCCACTCTTCCACCACTTCACCACCGCCATCGACACCGAGAACGTCCGCTTCGTGTTCCATGCTGTGAAAGACACCATCCTGCAGGAGAA CCTGAAGGACATCATGCTGCAGTGAGCGAGGAAGCCCCGGGGTTTGTCGTCGTTGAGCAGCCCCCACGGCTGTCGGTCAGACTCTTGGGT GTGTGTTGTCTGTGTGGTCCTTGAGTGGGTTTCTCGGATCCGTGCCCTGGAATACCTGGCTCAGGAATGCTGTCAGACCAGCCAGCCAGC GAGCTCTAGGCAAAAGGACATGGAAACTGTCACGTTAGCTACTGAATCCTGGGGGCGAGTGAAACTACTGAAAATCCGAGTGATGATGTT GTGAATACGGAACACCTAATCACACAGCTTGCTTTGCTTTTACAGAAACGTTCCTCTTTTTCTGACGCAGTTTAATTGAGGACCGTGTTG TGTGTGTATGTGTGTACACACGCTCTGTCTTTAATGACAGAAACACAAAAACCAGCTGGCCTTGCAGACGGCTTTTCTAACTCACAAGTC TTCCCTGAGACAGACTAACCTGAAAGCTTTGCCTAACAGTAGCTTGTAGAGATCCAGTGCACGCCGATGCTGCTAAACTCAGTGCCTGAG CCCGGCCCTGCAGCCCCAGCCGCAGTGTCTGAAGGCCACCTCCCAAAGGGAGCACGTTGCCTTTTCAAACTCCCGTGCCGATTTCCTAAG AGCCCCTAGTCCAAGCCTCTCAGATGAAGCTGAGGAGCCGTGCCTAGGATCCCTTCCCAGCTCTGAGGACGGGCTGCAGAGCTCTGCAGG TGTGGATTCACCTTACGCCCCTACAGCAGGCTCAGCCCTTCCCACCCTGCCCCATGCCCAGCAGCACAACACGGAGTGAGACAGGATGCC CACGGTGACTGCCGCTCCGTCCGTGCACACACAGCGGTGCTCTTCTCCCCTTAGCCACCCACTGCCCAACCCAACGGCAAAGACACAGAA ACCAGGTCCCCTTGCAGACGGCTCTCCCATCTTCCTGCAAGTCATCTGCTCACACACAGTTGGCAGCACATAGCGTTTCCTTCTTTCAGA AACATTCCTCTTCTGGGGCTTCAGAAAGCTGGCAAGGCCACTAGCAGAGCTTTTGTTAATGCCCCAGCTGCTTGGCGAGCTAACAGCTGA CCTTTCGGGAAGCCCACAGACGCTGGAGGAATCTTGAGTTTCTCCAAACTGCCGCTCCACCAGTGCCTTTGGACAGCCGTGCCTGTTCGC CGCTCTCCCTAAGTCTGATTCTCATCGAGGCCCCTCGCTTCTATGACTGTGCTTGCAGAAGAGTAAACACTCTCGGATGCCGCTGTCCTG GGGGAGCCCGCGGGAGCCTGTGAATGTTGATACGAGCTGGCCAGTCCTGGGCCCAGCTCACTTGTCCAGCTACCTGCCAGGTGGCTTTCA CTGTGTTTAAAATACATTGCATTCCAAGCTGGTCCCCTCTGTGTATCACTCTACTGAGAAATCCTGCCTAGTGTGTTTTGGGATGTGTCC TAGCATTTACAAGAAAATGAAAAGCGTCCTCTTAATTGGCACCCGAATGTTGCTGTGGCTCAGTCACATATCCCAGGGCCCTCGTCCCGA GGCCGTGCTGCCCCGAGCCCCGAGCCCCTCTGCAGCTCACCCTTGGCTTGTTTTCCGCAAACCCGGTAAACGCAAGCCCTTGGGGCAGAT GCAGAAGCAGAAGAGGGAGGGGAAACCTGCCTCTGGGTCACCCTGTTAGCACAGCGTTCTCATCGGGAGACAGCATGGAACTCTCTCTCG CAGTGCTCGAGGCTGTGTGTCAGTGTTTGCTGGGCTTGTGGCTCCTTTTTTGGCTGGATAAAGAAGTCGCTGTTTTTGTACTGCTTCTGT GGCTCTTCACAGACCTCACGGATGTGACCGGAGATGAGTGCCGATGACCACGTTTTAAAGGAGAAAGAGAGCTCCTGGTGGGGCCCTCGG GGTGGTCTCAGGTCCCATTTGCAGTCTGCAACAGTGACGCGCAGCCCGGTCCGGAGCGTGGTGAGCTTTGTTTGCCTTCTGGGTCAGCTT TCGCTGTGTCTCCTGTGTGTGTTAGAATCCAGAGCCCAGAGGAAGTGCAAGCGGGTCCTCCGCCAACGGGGAGAGCCTCTTCGCGGCGCT GTTGGCGACAGCAGCGCTGTGATTCGCGTAGCAGGGGAGTTGTTTGAAACACCTTCCTGAGTAGTCCGGCCTTGTCAATGAGTGCTTGTT TTCCTTTAAACAGTCTGACATATTTACTCGTCACTTTCAAACCAGAAGCATGAGAGGAAGGAGATATTGTGGGGTCCGTTTAACTCGATA GAAAGCGCAGGGGGATGGCCCCCGGCGCGGGCTCTTGACCCGCTCAGCGCTGACCCCACCGCCCTGGCCGAGGCACTTGGCCTTGCTGAG CTGGACTTCCTCCTCCTCCTCCTCATGACCGGGGTGAATTAGAACGTTTTTAAAGACACCCCCTTCCAAATTCTGTAACACATTGTAATT GGAGAAGAAGGAAACTCTGCAAGGCTAAACTGTCATTCACAACTTGGCTACACATAGACTCTAGTCAGTTTTGTCTCCAGAACCTTAGGC TTTTGTATTTTTTAATTTTAATTTCACTGTTAATCCTTATTGTCTTTTTTATTAAGATGTTGGAAAAGCAGGAGGTAGTTGTGCCTCAAT TATTGCAAAAATGTAACAATAAAGTTCCTCAAAATAAGATCTGTTCCTCATAGCTATACTGTGTACACATAAGACGCATATAGGGTTTTA CTGAAATCTATTTTTAACTCTTATGTTCGTAGAGAAATTGTTTCAAGGATTTTGAGTCATAGGTCTGTAATTTATAGAGATCTCTAGAAT TCTTATTGTAATTTTCCTACTTCTTTGATAAAAGAAAAATAAGTCAGATTGTTAACTCCAAGATTGAAAAAAAAAACTCTTGAAAGAAGA TTATTAGTTGTAACTAATTTAGGGGTTCTGGGCACAGACATCTAACCTGGTATTGTAAGGCAGAGGCTCCCATTGGAATGGTAGTGGTCC GGGTCAGTTGTTCATGGTGTAAGCTTTGCACAGTGTATTAACATTGGGAGGGTCTGGCTTGAAAATTTGGCCACCCTCAGCCTCTGAATG >In-frame_ENST00000544935_ENST00000275364_TCGA-24-1847_PRKAR1B_chr7_645829_-_GNA12_chr7_2773135_length(amino acids)=389AA_start in transcript=115_stop in transcript=1284 MASPPACPSEEDESLKGCELYVQLHGIQQVLKDCIVHLCISKPERPMKFLREHFEKLEKEENRQILARQKSNSQSDSHDEEVSPTPPNPV VKARRRRGGVSAEVYTEEDAVSYVRKVIPKDYKTMTALAKAISKNVLFAHLDDNERSDIFDAMFPVTHIAGETVIQQGNEGDNFYVVDQG EVDGESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLM EDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRLEDVQRYLVQCFDRKRRNRSKPLFHHFTT -------------------------------------------------------------- >In-frame_ENST00000406797_ENST00000275364_TCGA-24-1847_PRKAR1B_chr7_645829_-_GNA12_chr7_2773135_length(transcript)=4414nt_BP=724nt AGTTTCTGCCGCCGCCACCCTGGCAGGATGGGGCAACGGTGTGCGGTAGGAGGATGAGGTTGATTCCCTTTCCTGCAGGGCTGGGCTTGT GGGTTAGGACCGTCACCAAGAGGCTCCTCCTAGGCCTCCGTGACCTCTGGATCCCCAAGAAAGGAAGGAAGCAGCCACCCTCGCCATGGC CTCCCCGCCCGCCTGCCCCTCGGAGGAGGACGAGAGCCTGAAGGGCTGTGAGCTGTACGTGCAGCTGCACGGGATCCAGCAGGTCCTCAA AGACTGTATCGTCCACCTCTGCATCTCCAAGCCCGAACGCCCCATGAAGTTCCTCCGGGAGCACTTCGAGAAGCTGGAGAAGGAAGAAAA CAGGCAGATTTTGGCGCGGCAAAAGTCAAACTCACAGTCGGACTCCCATGATGAGGAGGTGTCGCCCACCCCCCCGAACCCTGTGGTGAA GGCCCGCCGCCGGCGAGGAGGCGTGAGTGCCGAGGTGTACACCGAGGAGGACGCCGTGTCCTACGTCAGGAAGGTGATTCCCAAGGACTA CAAAACCATGACTGCGCTGGCCAAGGCCATCTCCAAGAACGTGCTCTTCGCTCACCTGGATGACAACGAGAGGAGTGACATATTCGATGC CATGTTCCCTGTCACTCACATCGCTGGGGAGACTGTTATACAGCAAGGGAATGAAGGAGACAACTTCTATGTCGTTGATCAAGGGGAAGT GGATGGGGAGTCGGTGAAGTACTTCCTGGACAACTTGGACCGGATCGGCCAGCTGAATTACTTTCCTAGTAAGCAAGATATCCTGCTGGC TAGGAAAGCCACCAAGGGAATTGTGGAGCATGACTTCGTTATTAAGAAGATCCCCTTTAAGATGGTGGATGTGGGCGGCCAGCGGTCCCA GCGCCAGAAGTGGTTCCAGTGCTTCGACGGGATCACGTCCATCCTGTTCATGGTCTCCTCCAGCGAGTACGACCAGGTCCTCATGGAGGA CAGGCGCACCAACCGGCTGGTGGAGTCCATGAACATCTTCGAGACCATCGTCAACAACAAGCTCTTCTTCAACGTCTCCATCATTCTCTT CCTCAACAAGATGGACCTCCTGGTGGAGAAGGTGAAGACCGTGAGCATCAAGAAGCACTTCCCGGACTTCAGGGGCGACCCGCACAGGCT GGAGGACGTCCAGCGCTACCTGGTCCAGTGCTTCGACAGGAAGAGACGGAACCGCAGCAAGCCACTCTTCCACCACTTCACCACCGCCAT CGACACCGAGAACGTCCGCTTCGTGTTCCATGCTGTGAAAGACACCATCCTGCAGGAGAACCTGAAGGACATCATGCTGCAGTGAGCGAG GAAGCCCCGGGGTTTGTCGTCGTTGAGCAGCCCCCACGGCTGTCGGTCAGACTCTTGGGTGTGTGTTGTCTGTGTGGTCCTTGAGTGGGT TTCTCGGATCCGTGCCCTGGAATACCTGGCTCAGGAATGCTGTCAGACCAGCCAGCCAGCGAGCTCTAGGCAAAAGGACATGGAAACTGT CACGTTAGCTACTGAATCCTGGGGGCGAGTGAAACTACTGAAAATCCGAGTGATGATGTTGTGAATACGGAACACCTAATCACACAGCTT GCTTTGCTTTTACAGAAACGTTCCTCTTTTTCTGACGCAGTTTAATTGAGGACCGTGTTGTGTGTGTATGTGTGTACACACGCTCTGTCT TTAATGACAGAAACACAAAAACCAGCTGGCCTTGCAGACGGCTTTTCTAACTCACAAGTCTTCCCTGAGACAGACTAACCTGAAAGCTTT GCCTAACAGTAGCTTGTAGAGATCCAGTGCACGCCGATGCTGCTAAACTCAGTGCCTGAGCCCGGCCCTGCAGCCCCAGCCGCAGTGTCT GAAGGCCACCTCCCAAAGGGAGCACGTTGCCTTTTCAAACTCCCGTGCCGATTTCCTAAGAGCCCCTAGTCCAAGCCTCTCAGATGAAGC TGAGGAGCCGTGCCTAGGATCCCTTCCCAGCTCTGAGGACGGGCTGCAGAGCTCTGCAGGTGTGGATTCACCTTACGCCCCTACAGCAGG CTCAGCCCTTCCCACCCTGCCCCATGCCCAGCAGCACAACACGGAGTGAGACAGGATGCCCACGGTGACTGCCGCTCCGTCCGTGCACAC ACAGCGGTGCTCTTCTCCCCTTAGCCACCCACTGCCCAACCCAACGGCAAAGACACAGAAACCAGGTCCCCTTGCAGACGGCTCTCCCAT CTTCCTGCAAGTCATCTGCTCACACACAGTTGGCAGCACATAGCGTTTCCTTCTTTCAGAAACATTCCTCTTCTGGGGCTTCAGAAAGCT GGCAAGGCCACTAGCAGAGCTTTTGTTAATGCCCCAGCTGCTTGGCGAGCTAACAGCTGACCTTTCGGGAAGCCCACAGACGCTGGAGGA ATCTTGAGTTTCTCCAAACTGCCGCTCCACCAGTGCCTTTGGACAGCCGTGCCTGTTCGCCGCTCTCCCTAAGTCTGATTCTCATCGAGG CCCCTCGCTTCTATGACTGTGCTTGCAGAAGAGTAAACACTCTCGGATGCCGCTGTCCTGGGGGAGCCCGCGGGAGCCTGTGAATGTTGA TACGAGCTGGCCAGTCCTGGGCCCAGCTCACTTGTCCAGCTACCTGCCAGGTGGCTTTCACTGTGTTTAAAATACATTGCATTCCAAGCT GGTCCCCTCTGTGTATCACTCTACTGAGAAATCCTGCCTAGTGTGTTTTGGGATGTGTCCTAGCATTTACAAGAAAATGAAAAGCGTCCT CTTAATTGGCACCCGAATGTTGCTGTGGCTCAGTCACATATCCCAGGGCCCTCGTCCCGAGGCCGTGCTGCCCCGAGCCCCGAGCCCCTC TGCAGCTCACCCTTGGCTTGTTTTCCGCAAACCCGGTAAACGCAAGCCCTTGGGGCAGATGCAGAAGCAGAAGAGGGAGGGGAAACCTGC CTCTGGGTCACCCTGTTAGCACAGCGTTCTCATCGGGAGACAGCATGGAACTCTCTCTCGCAGTGCTCGAGGCTGTGTGTCAGTGTTTGC TGGGCTTGTGGCTCCTTTTTTGGCTGGATAAAGAAGTCGCTGTTTTTGTACTGCTTCTGTGGCTCTTCACAGACCTCACGGATGTGACCG GAGATGAGTGCCGATGACCACGTTTTAAAGGAGAAAGAGAGCTCCTGGTGGGGCCCTCGGGGTGGTCTCAGGTCCCATTTGCAGTCTGCA ACAGTGACGCGCAGCCCGGTCCGGAGCGTGGTGAGCTTTGTTTGCCTTCTGGGTCAGCTTTCGCTGTGTCTCCTGTGTGTGTTAGAATCC AGAGCCCAGAGGAAGTGCAAGCGGGTCCTCCGCCAACGGGGAGAGCCTCTTCGCGGCGCTGTTGGCGACAGCAGCGCTGTGATTCGCGTA GCAGGGGAGTTGTTTGAAACACCTTCCTGAGTAGTCCGGCCTTGTCAATGAGTGCTTGTTTTCCTTTAAACAGTCTGACATATTTACTCG TCACTTTCAAACCAGAAGCATGAGAGGAAGGAGATATTGTGGGGTCCGTTTAACTCGATAGAAAGCGCAGGGGGATGGCCCCCGGCGCGG GCTCTTGACCCGCTCAGCGCTGACCCCACCGCCCTGGCCGAGGCACTTGGCCTTGCTGAGCTGGACTTCCTCCTCCTCCTCCTCATGACC GGGGTGAATTAGAACGTTTTTAAAGACACCCCCTTCCAAATTCTGTAACACATTGTAATTGGAGAAGAAGGAAACTCTGCAAGGCTAAAC TGTCATTCACAACTTGGCTACACATAGACTCTAGTCAGTTTTGTCTCCAGAACCTTAGGCTTTTGTATTTTTTAATTTTAATTTCACTGT TAATCCTTATTGTCTTTTTTATTAAGATGTTGGAAAAGCAGGAGGTAGTTGTGCCTCAATTATTGCAAAAATGTAACAATAAAGTTCCTC AAAATAAGATCTGTTCCTCATAGCTATACTGTGTACACATAAGACGCATATAGGGTTTTACTGAAATCTATTTTTAACTCTTATGTTCGT AGAGAAATTGTTTCAAGGATTTTGAGTCATAGGTCTGTAATTTATAGAGATCTCTAGAATTCTTATTGTAATTTTCCTACTTCTTTGATA AAAGAAAAATAAGTCAGATTGTTAACTCCAAGATTGAAAAAAAAAACTCTTGAAAGAAGATTATTAGTTGTAACTAATTTAGGGGTTCTG GGCACAGACATCTAACCTGGTATTGTAAGGCAGAGGCTCCCATTGGAATGGTAGTGGTCCGGGTCAGTTGTTCATGGTGTAAGCTTTGCA CAGTGTATTAACATTGGGAGGGTCTGGCTTGAAAATTTGGCCACCCTCAGCCTCTGAATGTTTATTAAAATAAATTTAGTCTTTCTTTGC >In-frame_ENST00000406797_ENST00000275364_TCGA-24-1847_PRKAR1B_chr7_645829_-_GNA12_chr7_2773135_length(amino acids)=402AA_start in transcript=136_stop in transcript=1344 MDPQERKEAATLAMASPPACPSEEDESLKGCELYVQLHGIQQVLKDCIVHLCISKPERPMKFLREHFEKLEKEENRQILARQKSNSQSDS HDEEVSPTPPNPVVKARRRRGGVSAEVYTEEDAVSYVRKVIPKDYKTMTALAKAISKNVLFAHLDDNERSDIFDAMFPVTHIAGETVIQQ GNEGDNFYVVDQGEVDGESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSIL FMVSSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRLEDVQRYLVQCFDRKR -------------------------------------------------------------- >In-frame_ENST00000403562_ENST00000275364_TCGA-24-1847_PRKAR1B_chr7_645829_-_GNA12_chr7_2773135_length(transcript)=4322nt_BP=632nt GTGAGGGCCAAGCAGGAACAGGGGTCACGGGGCAAGGAGCACGTGGCAGCGCAGGAAACAGGAAGGAAGCAGCCACCCTCGCCATGGCCT CCCCGCCCGCCTGCCCCTCGGAGGAGGACGAGAGCCTGAAGGGCTGTGAGCTGTACGTGCAGCTGCACGGGATCCAGCAGGTCCTCAAAG ACTGTATCGTCCACCTCTGCATCTCCAAGCCCGAACGCCCCATGAAGTTCCTCCGGGAGCACTTCGAGAAGCTGGAGAAGGAAGAAAACA GGCAGATTTTGGCGCGGCAAAAGTCAAACTCACAGTCGGACTCCCATGATGAGGAGGTGTCGCCCACCCCCCCGAACCCTGTGGTGAAGG CCCGCCGCCGGCGAGGAGGCGTGAGTGCCGAGGTGTACACCGAGGAGGACGCCGTGTCCTACGTCAGGAAGGTGATTCCCAAGGACTACA AAACCATGACTGCGCTGGCCAAGGCCATCTCCAAGAACGTGCTCTTCGCTCACCTGGATGACAACGAGAGGAGTGACATATTCGATGCCA TGTTCCCTGTCACTCACATCGCTGGGGAGACTGTTATACAGCAAGGGAATGAAGGAGACAACTTCTATGTCGTTGATCAAGGGGAAGTGG ATGGGGAGTCGGTGAAGTACTTCCTGGACAACTTGGACCGGATCGGCCAGCTGAATTACTTTCCTAGTAAGCAAGATATCCTGCTGGCTA GGAAAGCCACCAAGGGAATTGTGGAGCATGACTTCGTTATTAAGAAGATCCCCTTTAAGATGGTGGATGTGGGCGGCCAGCGGTCCCAGC GCCAGAAGTGGTTCCAGTGCTTCGACGGGATCACGTCCATCCTGTTCATGGTCTCCTCCAGCGAGTACGACCAGGTCCTCATGGAGGACA GGCGCACCAACCGGCTGGTGGAGTCCATGAACATCTTCGAGACCATCGTCAACAACAAGCTCTTCTTCAACGTCTCCATCATTCTCTTCC TCAACAAGATGGACCTCCTGGTGGAGAAGGTGAAGACCGTGAGCATCAAGAAGCACTTCCCGGACTTCAGGGGCGACCCGCACAGGCTGG AGGACGTCCAGCGCTACCTGGTCCAGTGCTTCGACAGGAAGAGACGGAACCGCAGCAAGCCACTCTTCCACCACTTCACCACCGCCATCG ACACCGAGAACGTCCGCTTCGTGTTCCATGCTGTGAAAGACACCATCCTGCAGGAGAACCTGAAGGACATCATGCTGCAGTGAGCGAGGA AGCCCCGGGGTTTGTCGTCGTTGAGCAGCCCCCACGGCTGTCGGTCAGACTCTTGGGTGTGTGTTGTCTGTGTGGTCCTTGAGTGGGTTT CTCGGATCCGTGCCCTGGAATACCTGGCTCAGGAATGCTGTCAGACCAGCCAGCCAGCGAGCTCTAGGCAAAAGGACATGGAAACTGTCA CGTTAGCTACTGAATCCTGGGGGCGAGTGAAACTACTGAAAATCCGAGTGATGATGTTGTGAATACGGAACACCTAATCACACAGCTTGC TTTGCTTTTACAGAAACGTTCCTCTTTTTCTGACGCAGTTTAATTGAGGACCGTGTTGTGTGTGTATGTGTGTACACACGCTCTGTCTTT AATGACAGAAACACAAAAACCAGCTGGCCTTGCAGACGGCTTTTCTAACTCACAAGTCTTCCCTGAGACAGACTAACCTGAAAGCTTTGC CTAACAGTAGCTTGTAGAGATCCAGTGCACGCCGATGCTGCTAAACTCAGTGCCTGAGCCCGGCCCTGCAGCCCCAGCCGCAGTGTCTGA AGGCCACCTCCCAAAGGGAGCACGTTGCCTTTTCAAACTCCCGTGCCGATTTCCTAAGAGCCCCTAGTCCAAGCCTCTCAGATGAAGCTG AGGAGCCGTGCCTAGGATCCCTTCCCAGCTCTGAGGACGGGCTGCAGAGCTCTGCAGGTGTGGATTCACCTTACGCCCCTACAGCAGGCT CAGCCCTTCCCACCCTGCCCCATGCCCAGCAGCACAACACGGAGTGAGACAGGATGCCCACGGTGACTGCCGCTCCGTCCGTGCACACAC AGCGGTGCTCTTCTCCCCTTAGCCACCCACTGCCCAACCCAACGGCAAAGACACAGAAACCAGGTCCCCTTGCAGACGGCTCTCCCATCT TCCTGCAAGTCATCTGCTCACACACAGTTGGCAGCACATAGCGTTTCCTTCTTTCAGAAACATTCCTCTTCTGGGGCTTCAGAAAGCTGG CAAGGCCACTAGCAGAGCTTTTGTTAATGCCCCAGCTGCTTGGCGAGCTAACAGCTGACCTTTCGGGAAGCCCACAGACGCTGGAGGAAT CTTGAGTTTCTCCAAACTGCCGCTCCACCAGTGCCTTTGGACAGCCGTGCCTGTTCGCCGCTCTCCCTAAGTCTGATTCTCATCGAGGCC CCTCGCTTCTATGACTGTGCTTGCAGAAGAGTAAACACTCTCGGATGCCGCTGTCCTGGGGGAGCCCGCGGGAGCCTGTGAATGTTGATA CGAGCTGGCCAGTCCTGGGCCCAGCTCACTTGTCCAGCTACCTGCCAGGTGGCTTTCACTGTGTTTAAAATACATTGCATTCCAAGCTGG TCCCCTCTGTGTATCACTCTACTGAGAAATCCTGCCTAGTGTGTTTTGGGATGTGTCCTAGCATTTACAAGAAAATGAAAAGCGTCCTCT TAATTGGCACCCGAATGTTGCTGTGGCTCAGTCACATATCCCAGGGCCCTCGTCCCGAGGCCGTGCTGCCCCGAGCCCCGAGCCCCTCTG CAGCTCACCCTTGGCTTGTTTTCCGCAAACCCGGTAAACGCAAGCCCTTGGGGCAGATGCAGAAGCAGAAGAGGGAGGGGAAACCTGCCT CTGGGTCACCCTGTTAGCACAGCGTTCTCATCGGGAGACAGCATGGAACTCTCTCTCGCAGTGCTCGAGGCTGTGTGTCAGTGTTTGCTG GGCTTGTGGCTCCTTTTTTGGCTGGATAAAGAAGTCGCTGTTTTTGTACTGCTTCTGTGGCTCTTCACAGACCTCACGGATGTGACCGGA GATGAGTGCCGATGACCACGTTTTAAAGGAGAAAGAGAGCTCCTGGTGGGGCCCTCGGGGTGGTCTCAGGTCCCATTTGCAGTCTGCAAC AGTGACGCGCAGCCCGGTCCGGAGCGTGGTGAGCTTTGTTTGCCTTCTGGGTCAGCTTTCGCTGTGTCTCCTGTGTGTGTTAGAATCCAG AGCCCAGAGGAAGTGCAAGCGGGTCCTCCGCCAACGGGGAGAGCCTCTTCGCGGCGCTGTTGGCGACAGCAGCGCTGTGATTCGCGTAGC AGGGGAGTTGTTTGAAACACCTTCCTGAGTAGTCCGGCCTTGTCAATGAGTGCTTGTTTTCCTTTAAACAGTCTGACATATTTACTCGTC ACTTTCAAACCAGAAGCATGAGAGGAAGGAGATATTGTGGGGTCCGTTTAACTCGATAGAAAGCGCAGGGGGATGGCCCCCGGCGCGGGC TCTTGACCCGCTCAGCGCTGACCCCACCGCCCTGGCCGAGGCACTTGGCCTTGCTGAGCTGGACTTCCTCCTCCTCCTCCTCATGACCGG GGTGAATTAGAACGTTTTTAAAGACACCCCCTTCCAAATTCTGTAACACATTGTAATTGGAGAAGAAGGAAACTCTGCAAGGCTAAACTG TCATTCACAACTTGGCTACACATAGACTCTAGTCAGTTTTGTCTCCAGAACCTTAGGCTTTTGTATTTTTTAATTTTAATTTCACTGTTA ATCCTTATTGTCTTTTTTATTAAGATGTTGGAAAAGCAGGAGGTAGTTGTGCCTCAATTATTGCAAAAATGTAACAATAAAGTTCCTCAA AATAAGATCTGTTCCTCATAGCTATACTGTGTACACATAAGACGCATATAGGGTTTTACTGAAATCTATTTTTAACTCTTATGTTCGTAG AGAAATTGTTTCAAGGATTTTGAGTCATAGGTCTGTAATTTATAGAGATCTCTAGAATTCTTATTGTAATTTTCCTACTTCTTTGATAAA AGAAAAATAAGTCAGATTGTTAACTCCAAGATTGAAAAAAAAAACTCTTGAAAGAAGATTATTAGTTGTAACTAATTTAGGGGTTCTGGG CACAGACATCTAACCTGGTATTGTAAGGCAGAGGCTCCCATTGGAATGGTAGTGGTCCGGGTCAGTTGTTCATGGTGTAAGCTTTGCACA GTGTATTAACATTGGGAGGGTCTGGCTTGAAAATTTGGCCACCCTCAGCCTCTGAATGTTTATTAAAATAAATTTAGTCTTTCTTTGCTT >In-frame_ENST00000403562_ENST00000275364_TCGA-24-1847_PRKAR1B_chr7_645829_-_GNA12_chr7_2773135_length(amino acids)=389AA_start in transcript=83_stop in transcript=1252 MASPPACPSEEDESLKGCELYVQLHGIQQVLKDCIVHLCISKPERPMKFLREHFEKLEKEENRQILARQKSNSQSDSHDEEVSPTPPNPV VKARRRRGGVSAEVYTEEDAVSYVRKVIPKDYKTMTALAKAISKNVLFAHLDDNERSDIFDAMFPVTHIAGETVIQQGNEGDNFYVVDQG EVDGESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLM EDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRLEDVQRYLVQCFDRKRRNRSKPLFHHFTT -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for PRKAR1B-GNA12 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for PRKAR1B-GNA12 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for PRKAR1B-GNA12 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | PRKAR1B | C4751505 | PRKAR1B-related neurodegenerative dementia with intermediate filaments | 2 | ORPHANET |
| Tgene | GNA12 | C0009324 | Ulcerative Colitis | 1 | CTD_human |
| Tgene | GNA12 | C0033975 | Psychotic Disorders | 1 | PSYGENET |
| Tgene | GNA12 | C0151744 | Myocardial Ischemia | 1 | CTD_human |
| Tgene | GNA12 | C0349204 | Nonorganic psychosis | 1 | PSYGENET |
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