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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:PRKCA-CDH8 (FusionGDB2 ID:68267)

Fusion Gene Summary for PRKCA-CDH8

check button Fusion gene summary
Fusion gene informationFusion gene name: PRKCA-CDH8
Fusion gene ID: 68267
HgeneTgene
Gene symbol

PRKCA

CDH8

Gene ID

5578

1006

Gene nameprotein kinase C alphacadherin 8
SynonymsAAG6|PKC-alpha|PKCA|PKCI+/-|PKCalpha|PRKACANbla04261
Cytomap

17q24.2

16q21

Type of geneprotein-codingprotein-coding
Descriptionprotein kinase C alpha typePKC-Aaging-associated gene 6cadherin-8cadherin 8, type 2
Modification date2020032720200313
UniProtAcc.

P55286

Ensembl transtripts involved in fusion geneENST00000413366, ENST00000583361, 
ENST00000577730, ENST00000299345, 
ENST00000577390, ENST00000584337, 
ENST00000580044, 
Fusion gene scores* DoF score44 X 23 X 14=141686 X 4 X 4=96
# samples 466
** MAII scorelog2(46/14168*10)=-4.94485844580754
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(6/96*10)=-0.678071905112638
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: PRKCA [Title/Abstract] AND CDH8 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointPRKCA(64685165)-CDH8(61935377), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgenePRKCA

GO:0006468

protein phosphorylation

10770950

HgenePRKCA

GO:0035408

histone H3-T6 phosphorylation

20228790

HgenePRKCA

GO:0043536

positive regulation of blood vessel endothelial cell migration

20011604

HgenePRKCA

GO:0090330

regulation of platelet aggregation

12724315


check buttonFusion gene breakpoints across PRKCA (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across CDH8 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-AC-A5XU-01APRKCAchr17

64685165

+CDH8chr16

61935377

-
ChimerDB4BRCATCGA-AC-A5XU-01APRKCAchr17

64685165

+CDH8chr16

61935377

-
ChimerDB4BRCATCGA-AC-A5XU-01APRKCAchr17

64685165

-CDH8chr16

61935377

-


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Fusion Gene ORF analysis for PRKCA-CDH8

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000413366ENST00000577730PRKCAchr17

64685165

+CDH8chr16

61935377

-
In-frameENST00000413366ENST00000299345PRKCAchr17

64685165

+CDH8chr16

61935377

-
In-frameENST00000413366ENST00000577390PRKCAchr17

64685165

+CDH8chr16

61935377

-
In-frameENST00000413366ENST00000584337PRKCAchr17

64685165

+CDH8chr16

61935377

-
5CDS-intronENST00000413366ENST00000580044PRKCAchr17

64685165

+CDH8chr16

61935377

-
intron-3CDSENST00000583361ENST00000577730PRKCAchr17

64685165

+CDH8chr16

61935377

-
intron-3CDSENST00000583361ENST00000299345PRKCAchr17

64685165

+CDH8chr16

61935377

-
intron-3CDSENST00000583361ENST00000577390PRKCAchr17

64685165

+CDH8chr16

61935377

-
intron-3CDSENST00000583361ENST00000584337PRKCAchr17

64685165

+CDH8chr16

61935377

-
intron-intronENST00000583361ENST00000580044PRKCAchr17

64685165

+CDH8chr16

61935377

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000413366PRKCAchr1764685165+ENST00000577730CDH8chr1661935377-8502944142926970
ENST00000413366PRKCAchr1764685165+ENST00000299345CDH8chr1661935377-3465944142929971
ENST00000413366PRKCAchr1764685165+ENST00000577390CDH8chr1661935377-94589441430911025
ENST00000413366PRKCAchr1764685165+ENST00000584337CDH8chr1661935377-4156944142290758

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000413366ENST00000577730PRKCAchr1764685165+CDH8chr1661935377-0.0001032640.99989676
ENST00000413366ENST00000299345PRKCAchr1764685165+CDH8chr1661935377-0.000285820.9997142
ENST00000413366ENST00000577390PRKCAchr1764685165+CDH8chr1661935377-0.0001382230.9998617
ENST00000413366ENST00000584337PRKCAchr1764685165+CDH8chr1661935377-0.0003763660.99962366

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Fusion Genomic Features for PRKCA-CDH8


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for PRKCA-CDH8


check button Go to

FGviewer for the breakpoints of chr17:64685165-chr16:61935377

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.CDH8

P55286

FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePRKCAchr17:64685165chr16:61935377ENST00000413366+817158_275306.0673.0DomainC2
HgenePRKCAchr17:64685165chr16:61935377ENST00000413366+817101_151306.0673.0Zinc fingerPhorbol-ester/DAG-type 2
HgenePRKCAchr17:64685165chr16:61935377ENST00000413366+81736_86306.0673.0Zinc fingerPhorbol-ester/DAG-type 1
TgeneCDH8chr17:64685165chr16:61935377ENST00000577390112168_27684.0800.0DomainCadherin 2
TgeneCDH8chr17:64685165chr16:61935377ENST00000577390112277_39184.0800.0DomainCadherin 3
TgeneCDH8chr17:64685165chr16:61935377ENST00000577390112392_49484.0800.0DomainCadherin 4
TgeneCDH8chr17:64685165chr16:61935377ENST00000577390112495_61684.0800.0DomainCadherin 5
TgeneCDH8chr17:64685165chr16:61935377ENST00000577390112643_79984.0800.0Topological domainCytoplasmic
TgeneCDH8chr17:64685165chr16:61935377ENST00000577390112622_64284.0800.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePRKCAchr17:64685165chr16:61935377ENST00000413366+817339_597306.0673.0DomainProtein kinase
HgenePRKCAchr17:64685165chr16:61935377ENST00000413366+817598_668306.0673.0DomainAGC-kinase C-terminal
HgenePRKCAchr17:64685165chr16:61935377ENST00000413366+817345_353306.0673.0Nucleotide bindingATP
TgeneCDH8chr17:64685165chr16:61935377ENST0000057739011262_16784.0800.0DomainCadherin 1
TgeneCDH8chr17:64685165chr16:61935377ENST0000057739011262_62184.0800.0Topological domainExtracellular


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Fusion Gene Sequence for PRKCA-CDH8


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000413366_ENST00000577730_TCGA-AC-A5XU-01A_PRKCA_chr17_64685165_+_CDH8_chr16_61935377_length(transcript)=8502nt_BP=944nt
GAGGCAAGAGGTGGTTGGGGGGGACCATGGCTGACGTTTTCCCGGGCAACGACTCCACGGCGTCTCAGGACGTGGCCAACCGCTTCGCCC
GCAAAGGGGCGCTGAGGCAGAAGAACGTGCACGAGGTGAAGGACCACAAATTCATCGCGCGCTTCTTCAAGCAGCCCACCTTCTGCAGCC
ACTGCACCGACTTCATCTGGGGGTTTGGGAAACAAGGCTTCCAGTGCCAAGTTTGCTGTTTTGTGGTCCACAAGAGGTGCCATGAATTTG
TTACTTTTTCTTGTCCGGGTGCGGATAAGGGACCCGACACTGATGACCCCAGGAGCAAGCACAAGTTCAAAATCCACACTTACGGAAGCC
CCACCTTCTGCGATCACTGTGGGTCACTGCTCTATGGACTTATCCATCAAGGGATGAAATGTGACACCTGCGATATGAACGTTCACAAGC
AATGCGTCATCAATGTCCCCAGCCTCTGCGGAATGGATCACACTGAGAAGAGGGGGCGGATTTACCTAAAGGCTGAGGTTGCTGATGAAA
AGCTCCATGTCACAGTACGAGATGCAAAAAATCTAATCCCTATGGATCCAAACGGGCTTTCAGATCCTTATGTGAAGCTGAAACTTATTC
CTGATCCCAAGAATGAAAGCAAGCAAAAAACCAAAACCATCCGCTCCACACTAAATCCGCAGTGGAATGAGTCCTTTACATTCAAATTGA
AACCTTCAGACAAAGACCGACGACTGTCTGTAGAAATCTGGGACTGGGATCGAACAACAAGGAATGACTTCATGGGATCCCTTTCCTTTG
GAGTTTCGGAGCTGATGAAGATGCCGGCCAGTGGATGGTACAAGTTGCTTAACCAAGAAGAAGGTGAGTACTACAACGTACCCATTCCGG
AAGGGGACGAGGAAGGAAACATGGAACTCAGGCAGAAATTCGAGCTACACACAGACCTGGATCCTGGGAGCAAAAAAATCAAGTATATCC
TATCAGGTGATGGAGCTGGGACCATATTTCAAATAAATGATGTAACTGGAGATATCCATGCTATAAAAAGACTTGACCGGGAGGAAAAGG
CTGAGTATACCCTAACAGCTCAAGCAGTGGACTGGGAGACAAGCAAACCTCTGGAGCCTCCTTCTGAATTTATTATTAAAGTTCAAGACA
TCAATGACAATGCACCAGAGTTTCTTAATGGACCCTATCATGCTACTGTGCCAGAAATGTCCATTTTGGGTACATCTGTCACTAACGTCA
CTGCGACCGACGCTGATGACCCAGTTTATGGAAACAGTGCAAAGTTGGTTTATAGTATATTGGAAGGGCAGCCTTATTTTTCCATTGAGC
CTGAAACAGCTATTATAAAAACTGCCCTTCCCAACATGGACAGAGAAGCCAAGGAGGAGTACCTGGTTGTTATCCAAGCCAAAGATATGG
GTGGACACTCTGGTGGCCTGTCTGGGACCACGACACTTACAGTGACTCTTACTGATGTTAATGACAATCCTCCAAAATTTGCACAGAGCC
TGTATCACTTCTCAGTACCGGAAGATGTGGTTCTTGGCACTGCAATAGGAAGGGTGAAGGCCAATGATCAGGATATTGGTGAAAATGCAC
AGTCATCATATGATATCATCGATGGAGATGGAACAGCACTTTTTGAAATCACTTCTGATGCCCAGGCCCAGGATGGCATTATAAGGCTAA
GAAAACCTCTGGACTTTGAGACCAAAAAATCCTATACGCTAAAGGTAGAGGCAGCCAATGTCCATATTGACCCACGCTTCAGTGGCAGGG
GGCCCTTTAAAGACACGGCGACAGTCAAAATCGTGGTTGAAGATGCTGATGAGCCTCCGGTCTTCTCTTCACCGACTTACCTACTTGAAG
TTCATGAAAATGCTGCTCTAAACTCCGTGATTGGGCAAGTGACTGCTCGTGACCCTGATATCACTTCCAGTCCTATAAGGTTTTCCATCG
ACCGGCACACTGACCTGGAGAGGCAGTTCAACATTAATGCAGACGATGGGAAGATAACGCTGGCAACACCACTTGACAGAGAATTAAGTG
TATGGCACAACATAACAATCATTGCTACTGAAATTAGGAACCACAGTCAGATATCACGAGTACCTGTTGCTATTAAAGTGCTGGATGTCA
ATGACAACGCCCCTGAATTCGCATCCGAATATGAGGCATTTTTATGTGAAAATGGAAAACCCGGCCAAGTCATTCAAACTGTTAGCGCCA
TGGACAAAGATGATCCCAAAAACGGACATTATTTCTTATACAGTCTCCTTCCAGAAATGGTCAACAATCCGAATTTCACCATCAAGAAAA
ATGAAGATAATTCCCTCAGTATTTTGGCAAAGCATAATGGATTCAACCGCCAGAAGCAAGAAGTCTATCTTTTACCAATCATAATCAGTG
ATAGTGGAAATCCTCCACTGAGCAGCACTAGCACCTTGACAATCAGGGTCTGTGGCTGCAGCAATGACGGTGTCGTCCAGTCTTGCAATG
TCGAAGCTTATGTCCTTCCAATTGGACTCAGTATGGGCGCCTTAATTGCCATATTAGCATGCATCATTTTGCTGTTAGTCATCGTGGTGC
TGTTTGTAACTCTACGGCGGCATAAAAATGAACCATTAATTATCAAAGATGATGAAGACGTTCGAGAAAACATCATTCGCTACGATGATG
AAGGAGGAGGGGAGGAGGACACAGAGGCTTTTGACATTGCAACTTTACAAAATCCAGATGGAATTAATGGATTTTTACCCCGGTGGGGCT
TGCCAATTCAGTGGTGGGAGGAGAGAAATCCCATTCAAACATGCTTGTTTTCTAGAAGCAGGATTCCTCGTTCCCTCCTCTTCATCTTCT
TCCACAAGGACACAAAGATAAACTGTATCACACAGTGGACTACATAAGAGACAGATGGTTTTATTGCTAGCGCGTGAATTTATTTGTTTA
ATCCTCGAAATAAATATTTTATTGATGTCCATTAATGCTTTTATTTATTAAGGTCGGTAATCTATAGATTAAGGGGATATATGGGAAAAA
ACTAAATTATATCCATTAATAATCCTTTAGATTGTTTTATATAAATATATATACAATGAATGTTTAATACATGTACATTTTGATGAGATG
AGTATGGCAGGCAATATTATCGAAAGGAGAGCTAATAGTCTCTTTAGAGTAGAAAGTGTTATTGTAACTGGAGATGGCAGGAACAGCATC
TTCCCAGACAAACTTTTGGACTGTTTTCTATTTTGTTCATAATCCTAGTATTTGGTGTTTTTACTACAAGCACAAACATCCTAAAGTATA
TTGATTCCTGTGAATATTTAAACTCTAGACTTTTAGATACCTACATCATGCCCTGCCCAATAAACATGCTTCAATTTACCCCCACAGTTT
TAGAGCAGGAACTGATTTGTACATAATTTCACTGTTTACGTTTTTAGCACTCCTATCCCTGATCTTCATGGTGATGCACAGAATGTCTTA
GACTCCAAAAAGGAACAGCACTAGAAGATGTGAGCATATTTAATTTGTAATGCAAACCTGCCATTTAGGAGTAGAAAATGTATGATAAAA
CTCAAGTATTACATGCAGATCATTTTAATTTTCTACTTTGCTTTAATGCAATATTGTTTATTCACTCCATGTATTGTATTCAGAGAAACT
CCTGTATTGTTTCCTACTTTGTGAAATATATTTTTATAAATACCTTTGTTGTCATTAATTTTTTTTTCAATCAGTGGAAGATCTATTAAC
AGAATCATCAACTCAAACTAAAATTCTAGAATACTCAACCAAATCATCCCAAGGGTCACTTTTGTTTGTAAGACTCTTTATTATAGAGAA
ACAGAGAAGAGAAATGGCTTGCCAGTGATCACACAGCAAGATACCAGCAGGGACATAAGAGGAACATGGAACACCTAAAGGCTAGTCCAG
CTGTGTCATTTGGGTCCTTCTGGAAGCAGACGCATTGGGCAGGGAAAACCTTCAGACAAGTTTGCAGACCTAAAACTTGTAACAATAGAG
GGATTGGGAGCAGGATTTGGCAAGAGAGTCTTAGACTGCAGTGCGGACCTGGCAAAATCTCTGCCAGTCTGACAGGGGGTTCTAGAGTGA
AAACACATCCATTAAAGCAGTCAGGCTGTGGTCCTCTGTCATCTCAGTCATTGGTGCGGGGCTGCTAAGAAGAGAACGGTTTTTGACTCA
AAAGCTGAACGCACCAACTTCTAGAGGCCACCTTCACTGTGACAGAAACTGCATGTTTAAATACTATACTAACAATTTATAACTATCCGG
TGGCTTAATCAACTTTTTATTGAGTTTCTGTTGCTGAGAATAAGTCATCTTTTATGCGTATTATTACGGCTAGTGAACACTTTTTCTTGA
GGTCAAAGGGATGGTCCAACATGACTTTAAAATATACTAGGACTTGGCACAGTGTCTAAAACAAGTGCTTGGTGAATGTAAATTATTAGT
AGTAGTTGCAGTAATAACCAATAGTAATATTCCAACTATCTTACACCTTCCAAACCAAGGAGAGATTATTATGTTTTATGTATCTCTTGA
ACACCAGACTCATTTCTAGTGTACTTTGAAGTGCCCAAAGATTATAGACACACAAATATGTCTAACAGAATAATTACAGTATTTTTTAAG
GAGTATAAAATCTGTATCCTCAAATATTGGTAATCAACAGGATAATCTTCGTACAGTGGTTTCTGTGAGCAGGAGATAATGTCTGCTCTA
CTAGTTGCCCAAATATCGCCTAAGTATTCTCTTTGCCTAGGAACACAGAATGAAAGCTTGCATCTCTTGCTGACTTTCTTTGCCACCACA
GTGTCAGCATTTTGTGTTTAAAAGCCTATTTCAGGTCTTGTAACATAGAATAAAGTGACTAATACCTTGATCCTAATAAGATTGACCTAT
ACTTTTAGAGTGTCATGAATTAAACTAAAAATCTCAGGAACTATCTCTCTCTTTCTCTCTTTCTCTCTCTCTCTCTCTCTCTCTCTCACA
CACACACACACACACACACACACACACACACAACAAACAAATAAAAAACACACATTTTGACTTGAAGTTTTACTTTAGCAATAGACTTGC
CAGGACTTTCCCAACCAAAAGATATCAATAAGGTTCCTAACATTTTCTAAGATTTAAGTATCCCATGCTCAATTTGTTAAATAACACATT
TTAAAAACTTTATTGAAATGACTATATTTTTAAAGCTATGTGCATTGTTGTCTGTTTCATCAACATTGACATAGCAGAAACAAGAGTACT
CTCTGCTAAATAGAGAAGAATGATTAAGTTGGAGCCAAGTGAGACAAAGTTATCTCCCTCTGCCTACCTCACAATTCAAGGTTCCCACCT
AGGGAACTGATGCATCCCTGGGTGATTGGACACAACATGGGATCAATTCAGCCTCTACTCTGCCTATGATTTGATCAAATCATATTAGCA
AAGTGTCTCTTAAACATCCATATATGAATATTAAAGAGTATTAAGGGGGGCATTTCTTAACAATATTTTTATGAGTATAGTTATAAGTTT
CTAAACATTTATAATACGATGACTAAAATATGCTATTTTTAAATTCAAGTGTTAACCTTGCCACACAGAATTATGACTTCTAGGGTGTAA
ACTTTAAAGTGAAACTGTTTTGAAAAAAATCTGCAGTTAAGTGTATGTGTATATATAGAAGAAAAGGAAACTTAGATTTACTGGTATCAC
CAGTGAAGCAAGAATGCTTAGAAAGATACAAATGTGTCTTTGGGAGAGTCTGCTTAATCAGATGCTTAAAGTAAGACAAGTCTCTGCATG
AGACTTAGAAATCTCCTAGGAGCAGCTGGATTCCACACTGAGACTCAACAGAGTTCTGGGCTATGCTGTATTTTGGAAAAGGAAAAGCGG
GTGCTGAGAGCTAAGTAGCCAATTACTCTTTATAGCCACATAAGGACTGAAGGCAAGTAGGCCCTTCCAACAAGTTGTATTATGCGATCA
CTGGCTTTGCAGGGAATCTCACGAATGTATAACCTTCTGATTGCCTTTTTGATTGAAAGTTCCATCTGAGATCAGGGCAGTGTAACCAGT
AATAAGATTTCAAAAAAATCCCATCACTGGCACTGTCGGAAAGGCTGAGCATGACTGAAATCCTATCATTGTCAGTCAAAAAGATAAGGT
AACAGCGGGCATCACTATAAAAGCTCTATAAATGCACAACTTAAACATGAATATCAACATTAAAAAGAATATATATATCCTTATACATAT
ATTTATAAATATATTCATATATATAAATATGCACATATATACACAATTCAGTTACTGGGGATAATTTATAGTTTTAATTTTTCATCTCAT
AATCTCACGCACTGCCAACAAATTGAAATTGTGGCTCTCTGTTTTCATGAATCTAACCTTGAATTTGAAAGAAGTTGAATTGAGGGTAAA
GGGTTTTAAAAGCAGCTTTTTATTTGTGAACAGAATAATGGCTCATAATACCTGGGATTAGAATTAAATATGTCACGTTGTGAGGCTGTA
CTTAGACTTTTTAAATGTCATTGTATTTTTTTGTGGACAAAATAATTGTAGAATATACTTTGCAGGAAATACTTTTCTATATTTTTTCAA
TTTCAATACTGTTTTATTTGCTATAAAAAGTGTCTTTGCACTGTTACTCAGCCAAACAGTGTTGAATGTATTATTTGCCCTTGTAATTAT
TGCTTCTTATGATAATTGTAGAAGAGCATGTCTTTATGATCTATCATTTAAAAATACATTTATTGTCATTGTAGTTTTAGTCAACACAAA
TTTATGGATTACATGGTATACTGTTGCTATTGAAGATATTCTAGTCCTAGTATTTTGAGCACAGACCTAGCGTTATGGAGGACATAAAAT
TTAAAAATTTCCTGACTTGATGGACTATCTGAGGAAAAAGAATTTTGTCTGTCACATTTATTGAGTATCTATCAGTACAGAAATTAAGCT
ACATGGTTGATACAGAAAGATTAAATACAGTAGCATTCTCAAACTTATTTTCTTTATTTATAAAATGTACCTAATCAATCTCATAAGAAC
TAATTGTTGAATTTTTTTTTTATCTATGGATAAATACTATTTGAGTCTGGGTTTAAGTTTGGTTGATCTGACACTAAATCCCCTTAACTT
TCAACTAAACAGTTATCTCTGTAATTATGAGACTTTTGATGATAAGAAATAGAAACTAAGTTATATATAGTGCTATGGAAGTACTGAGGA
GGAAGTAAGGGACCCCATATGGGAAGACTCAAGAAGACGTCACGGTGAAATTTTCCAAAAAGATGGGAACTCAAGAATGGGTGCAACAGA
AATCACAGCTTTTCCAAATACTAAAAGGGAAAATTATAAAAAGCACCAATGGCACACTTTTGGACATTCAGAAAGATCCAGAAATTAGGT
GCTTATAGGAAACTCTAGGTTTGCCAAATTGTAGTGTTTTATGGATAGGAAAAATGAAGTTCAGAAACGTTATAAGGAATTTTCAGGGTT
AAATTACACATCAAATATGTGAGAGAAACAGAAATTACATGCTGGTATTTGGGGTCATCTCCTGAGTTGTAATGTTGTAAGTGTTTTTGT
ATGTATTCTCCTCCTTCCTTTATGTGTGGAAGTTTCATCTAGGTCTCAAGGTTAGTAGGCATTTGCTGGTGAAAATAGTGCCTTTGGGTA
CTATTTCCCCAACTTGAGTTACCTGCCACCATCTAATTCACATCTTGAATGCAAGTATTATTTCTTGCAAGTATCCCTACTAATAGATAA
TAGATATTTCTATTATTATCCACAGATTACAGAAGAGGGTTGCTAGGAGGAATATCACAAGATGCTGTCTGAAGAGAAAGACTGTGGAAA
ACCATGGCTTCAATGAACTCAGAGGTCAGGACCAGAAAAGGAAATGAGAGGTCACCAAAGCCAAATGTTAATTTCTTGGGATTTCTTCTG
TACATGCAAAGAACTTCAGGCCATCCTATGATTCCTCAAAAATAAGAGGAAAATTTTAACAATTATGCTCTAAGATGGACCATGACAATT
TAGGAGTCATTGGGATCACCCCCCAAAGCCAAATGTTAATTTCTTGGGATTTCTTCTGTACATGCAAAGAACTTCAGGCCATCCTATGAT
CCCTCACAAATAAGAGGAAGATTTTAACAATTATGCTCTAAGATGGAACATGACAATTTAGGAGTCACTGGGATCACCCCCCCCACCTTT
CCAACGTTACTCTGCTTTAACTACAAATATGTCGAATGGTTTTCTAATTTTTCTTTAACTTAACCTCTAAAGTTCGAGAGCTGTCATCTT
TGTCAAGTCTGATTGTTGAGTATGTGAATGGATGTTTTTGGCTCAATGTTAGAGCCAAAATTTATAAATAATAATTATTTATACATAATG

>In-frame_ENST00000413366_ENST00000577730_TCGA-AC-A5XU-01A_PRKCA_chr17_64685165_+_CDH8_chr16_61935377_length(amino acids)=970AA_start in transcript=14_stop in transcript=2926
MGGTMADVFPGNDSTASQDVANRFARKGALRQKNVHEVKDHKFIARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHEFVTFSC
PGADKGPDTDDPRSKHKFKIHTYGSPTFCDHCGSLLYGLIHQGMKCDTCDMNVHKQCVINVPSLCGMDHTEKRGRIYLKAEVADEKLHVT
VRDAKNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNESFTFKLKPSDKDRRLSVEIWDWDRTTRNDFMGSLSFGVSEL
MKMPASGWYKLLNQEEGEYYNVPIPEGDEEGNMELRQKFELHTDLDPGSKKIKYILSGDGAGTIFQINDVTGDIHAIKRLDREEKAEYTL
TAQAVDWETSKPLEPPSEFIIKVQDINDNAPEFLNGPYHATVPEMSILGTSVTNVTATDADDPVYGNSAKLVYSILEGQPYFSIEPETAI
IKTALPNMDREAKEEYLVVIQAKDMGGHSGGLSGTTTLTVTLTDVNDNPPKFAQSLYHFSVPEDVVLGTAIGRVKANDQDIGENAQSSYD
IIDGDGTALFEITSDAQAQDGIIRLRKPLDFETKKSYTLKVEAANVHIDPRFSGRGPFKDTATVKIVVEDADEPPVFSSPTYLLEVHENA
ALNSVIGQVTARDPDITSSPIRFSIDRHTDLERQFNINADDGKITLATPLDRELSVWHNITIIATEIRNHSQISRVPVAIKVLDVNDNAP
EFASEYEAFLCENGKPGQVIQTVSAMDKDDPKNGHYFLYSLLPEMVNNPNFTIKKNEDNSLSILAKHNGFNRQKQEVYLLPIIISDSGNP
PLSSTSTLTIRVCGCSNDGVVQSCNVEAYVLPIGLSMGALIAILACIILLLVIVVLFVTLRRHKNEPLIIKDDEDVRENIIRYDDEGGGE

--------------------------------------------------------------
>In-frame_ENST00000413366_ENST00000299345_TCGA-AC-A5XU-01A_PRKCA_chr17_64685165_+_CDH8_chr16_61935377_length(transcript)=3465nt_BP=944nt
GAGGCAAGAGGTGGTTGGGGGGGACCATGGCTGACGTTTTCCCGGGCAACGACTCCACGGCGTCTCAGGACGTGGCCAACCGCTTCGCCC
GCAAAGGGGCGCTGAGGCAGAAGAACGTGCACGAGGTGAAGGACCACAAATTCATCGCGCGCTTCTTCAAGCAGCCCACCTTCTGCAGCC
ACTGCACCGACTTCATCTGGGGGTTTGGGAAACAAGGCTTCCAGTGCCAAGTTTGCTGTTTTGTGGTCCACAAGAGGTGCCATGAATTTG
TTACTTTTTCTTGTCCGGGTGCGGATAAGGGACCCGACACTGATGACCCCAGGAGCAAGCACAAGTTCAAAATCCACACTTACGGAAGCC
CCACCTTCTGCGATCACTGTGGGTCACTGCTCTATGGACTTATCCATCAAGGGATGAAATGTGACACCTGCGATATGAACGTTCACAAGC
AATGCGTCATCAATGTCCCCAGCCTCTGCGGAATGGATCACACTGAGAAGAGGGGGCGGATTTACCTAAAGGCTGAGGTTGCTGATGAAA
AGCTCCATGTCACAGTACGAGATGCAAAAAATCTAATCCCTATGGATCCAAACGGGCTTTCAGATCCTTATGTGAAGCTGAAACTTATTC
CTGATCCCAAGAATGAAAGCAAGCAAAAAACCAAAACCATCCGCTCCACACTAAATCCGCAGTGGAATGAGTCCTTTACATTCAAATTGA
AACCTTCAGACAAAGACCGACGACTGTCTGTAGAAATCTGGGACTGGGATCGAACAACAAGGAATGACTTCATGGGATCCCTTTCCTTTG
GAGTTTCGGAGCTGATGAAGATGCCGGCCAGTGGATGGTACAAGTTGCTTAACCAAGAAGAAGGTGAGTACTACAACGTACCCATTCCGG
AAGGGGACGAGGAAGGAAACATGGAACTCAGGCAGAAATTCGAGCTACACACAGACCTGGATCCTGGGAGCAAAAAAATCAAGTATATCC
TATCAGGTGATGGAGCTGGGACCATATTTCAAATAAATGATGTAACTGGAGATATCCATGCTATAAAAAGACTTGACCGGGAGGAAAAGG
CTGAGTATACCCTAACAGCTCAAGCAGTGGACTGGGAGACAAGCAAACCTCTGGAGCCTCCTTCTGAATTTATTATTAAAGTTCAAGACA
TCAATGACAATGCACCAGAGTTTCTTAATGGACCCTATCATGCTACTGTGCCAGAAATGTCCATTTTGGGTACATCTGTCACTAACGTCA
CTGCGACCGACGCTGATGACCCAGTTTATGGAAACAGTGCAAAGTTGGTTTATAGTATATTGGAAGGGCAGCCTTATTTTTCCATTGAGC
CTGAAACAGCTATTATAAAAACTGCCCTTCCCAACATGGACAGAGAAGCCAAGGAGGAGTACCTGGTTGTTATCCAAGCCAAAGATATGG
GTGGACACTCTGGTGGCCTGTCTGGGACCACGACACTTACAGTGACTCTTACTGATGTTAATGACAATCCTCCAAAATTTGCACAGAGCC
TGTATCACTTCTCAGTACCGGAAGATGTGGTTCTTGGCACTGCAATAGGAAGGGTGAAGGCCAATGATCAGGATATTGGTGAAAATGCAC
AGTCATCATATGATATCATCGATGGAGATGGAACAGCACTTTTTGAAATCACTTCTGATGCCCAGGCCCAGGATGGCATTATAAGGCTAA
GAAAACCTCTGGACTTTGAGACCAAAAAATCCTATACGCTAAAGGTAGAGGCAGCCAATGTCCATATTGACCCACGCTTCAGTGGCAGGG
GGCCCTTTAAAGACACGGCGACAGTCAAAATCGTGGTTGAAGATGCTGATGAGCCTCCGGTCTTCTCTTCACCGACTTACCTACTTGAAG
TTCATGAAAATGCTGCTCTAAACTCCGTGATTGGGCAAGTGACTGCTCGTGACCCTGATATCACTTCCAGTCCTATAAGGTTTTCCATCG
ACCGGCACACTGACCTGGAGAGGCAGTTCAACATTAATGCAGACGATGGGAAGATAACGCTGGCAACACCACTTGACAGAGAATTAAGTG
TATGGCACAACATAACAATCATTGCTACTGAAATTAGGAACCACAGTCAGATATCACGAGTACCTGTTGCTATTAAAGTGCTGGATGTCA
ATGACAACGCCCCTGAATTCGCATCCGAATATGAGGCATTTTTATGTGAAAATGGAAAACCCGGCCAAGTCATTCAAACTGTTAGCGCCA
TGGACAAAGATGATCCCAAAAACGGACATTATTTCTTATACAGTCTCCTTCCAGAAATGGTCAACAATCCGAATTTCACCATCAAGAAAA
ATGAAGATAATTCCCTCAGTATTTTGGCAAAGCATAATGGATTCAACCGCCAGAAGCAAGAAGTCTATCTTTTACCAATCATAATCAGTG
ATAGTGGAAATCCTCCACTGAGCAGCACTAGCACCTTGACAATCAGGGTCTGTGGCTGCAGCAATGACGGTGTCGTCCAGTCTTGCAATG
TCGAAGCTTATGTCCTTCCAATTGGACTCAGTATGGGCGCCTTAATTGCCATATTAGCATGCATCATTTTGCTGTTAGTCATCGTGGTGC
TGTTTGTAACTCTACGGCGGCATAAAAATGAACCATTAATTATCAAAGATGATGAAGACGTTCGAGAAAACATCATTCGCTACGATGATG
AAGGAGGAGGGGAGGAGGACACAGAGGCTTTTGACATTGCAACTTTACAAAATCCAGATGGAATTAATGGATTTTTACCCCGTAAGGATA
TTAAACCAGATTTGCAGTTTATGCCAAGATTACAGAAGAGGGTTGCTAGGAGGAATATCACAAGATGCTGTCTGAAGAGAAAGACTGTGG
AAAACCATGGCTTCAATGAACTCAGAGGTCAGGACCAGAAAAGGAAATGAGAGGTCACCAAAGCCAAATGTTAATTTCTTGGGATTTCTT
CTGTACATGCAAAGAACTTCAGGCCATCCTATGATTCCTCAAAAATAAGAGGAAAATTTTAACAATTATGCTCTAAGATGGACCATGACA
ATTTAGGAGTCATTGGGATCACCCCCCAAAGCCAAATGTTAATTTCTTGGGATTTCTTCTGTACATGCAAAGAACTTCAGGCCATCCTAT
GATCCCTCACAAATAAGAGGAAGATTTTAACAATTATGCTCTAAGATGGAACATGACAATTTAGGAGTCACTGGGATCACCCCCCCCACC
TTTCCAACGTTACTCTGCTTTAACTACAAATATGTCGAATGGTTTTCTAATTTTTCTTTAACTTAACCTCTAAAGTTCGAGAGCTGTCAT
CTTTGTCAAGTCTGATTGTTGAGTATGTGAATGGATGTTTTTGGCTCAATGTTAGAGCCAAAATTTATAAATAATAATTATTTATACATA

>In-frame_ENST00000413366_ENST00000299345_TCGA-AC-A5XU-01A_PRKCA_chr17_64685165_+_CDH8_chr16_61935377_length(amino acids)=971AA_start in transcript=14_stop in transcript=2929
MGGTMADVFPGNDSTASQDVANRFARKGALRQKNVHEVKDHKFIARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHEFVTFSC
PGADKGPDTDDPRSKHKFKIHTYGSPTFCDHCGSLLYGLIHQGMKCDTCDMNVHKQCVINVPSLCGMDHTEKRGRIYLKAEVADEKLHVT
VRDAKNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNESFTFKLKPSDKDRRLSVEIWDWDRTTRNDFMGSLSFGVSEL
MKMPASGWYKLLNQEEGEYYNVPIPEGDEEGNMELRQKFELHTDLDPGSKKIKYILSGDGAGTIFQINDVTGDIHAIKRLDREEKAEYTL
TAQAVDWETSKPLEPPSEFIIKVQDINDNAPEFLNGPYHATVPEMSILGTSVTNVTATDADDPVYGNSAKLVYSILEGQPYFSIEPETAI
IKTALPNMDREAKEEYLVVIQAKDMGGHSGGLSGTTTLTVTLTDVNDNPPKFAQSLYHFSVPEDVVLGTAIGRVKANDQDIGENAQSSYD
IIDGDGTALFEITSDAQAQDGIIRLRKPLDFETKKSYTLKVEAANVHIDPRFSGRGPFKDTATVKIVVEDADEPPVFSSPTYLLEVHENA
ALNSVIGQVTARDPDITSSPIRFSIDRHTDLERQFNINADDGKITLATPLDRELSVWHNITIIATEIRNHSQISRVPVAIKVLDVNDNAP
EFASEYEAFLCENGKPGQVIQTVSAMDKDDPKNGHYFLYSLLPEMVNNPNFTIKKNEDNSLSILAKHNGFNRQKQEVYLLPIIISDSGNP
PLSSTSTLTIRVCGCSNDGVVQSCNVEAYVLPIGLSMGALIAILACIILLLVIVVLFVTLRRHKNEPLIIKDDEDVRENIIRYDDEGGGE

--------------------------------------------------------------
>In-frame_ENST00000413366_ENST00000577390_TCGA-AC-A5XU-01A_PRKCA_chr17_64685165_+_CDH8_chr16_61935377_length(transcript)=9458nt_BP=944nt
GAGGCAAGAGGTGGTTGGGGGGGACCATGGCTGACGTTTTCCCGGGCAACGACTCCACGGCGTCTCAGGACGTGGCCAACCGCTTCGCCC
GCAAAGGGGCGCTGAGGCAGAAGAACGTGCACGAGGTGAAGGACCACAAATTCATCGCGCGCTTCTTCAAGCAGCCCACCTTCTGCAGCC
ACTGCACCGACTTCATCTGGGGGTTTGGGAAACAAGGCTTCCAGTGCCAAGTTTGCTGTTTTGTGGTCCACAAGAGGTGCCATGAATTTG
TTACTTTTTCTTGTCCGGGTGCGGATAAGGGACCCGACACTGATGACCCCAGGAGCAAGCACAAGTTCAAAATCCACACTTACGGAAGCC
CCACCTTCTGCGATCACTGTGGGTCACTGCTCTATGGACTTATCCATCAAGGGATGAAATGTGACACCTGCGATATGAACGTTCACAAGC
AATGCGTCATCAATGTCCCCAGCCTCTGCGGAATGGATCACACTGAGAAGAGGGGGCGGATTTACCTAAAGGCTGAGGTTGCTGATGAAA
AGCTCCATGTCACAGTACGAGATGCAAAAAATCTAATCCCTATGGATCCAAACGGGCTTTCAGATCCTTATGTGAAGCTGAAACTTATTC
CTGATCCCAAGAATGAAAGCAAGCAAAAAACCAAAACCATCCGCTCCACACTAAATCCGCAGTGGAATGAGTCCTTTACATTCAAATTGA
AACCTTCAGACAAAGACCGACGACTGTCTGTAGAAATCTGGGACTGGGATCGAACAACAAGGAATGACTTCATGGGATCCCTTTCCTTTG
GAGTTTCGGAGCTGATGAAGATGCCGGCCAGTGGATGGTACAAGTTGCTTAACCAAGAAGAAGGTGAGTACTACAACGTACCCATTCCGG
AAGGGGACGAGGAAGGAAACATGGAACTCAGGCAGAAATTCGAGCTACACACAGACCTGGATCCTGGGAGCAAAAAAATCAAGTATATCC
TATCAGGTGATGGAGCTGGGACCATATTTCAAATAAATGATGTAACTGGAGATATCCATGCTATAAAAAGACTTGACCGGGAGGAAAAGG
CTGAGTATACCCTAACAGCTCAAGCAGTGGACTGGGAGACAAGCAAACCTCTGGAGCCTCCTTCTGAATTTATTATTAAAGTTCAAGACA
TCAATGACAATGCACCAGAGTTTCTTAATGGACCCTATCATGCTACTGTGCCAGAAATGTCCATTTTGGGTACATCTGTCACTAACGTCA
CTGCGACCGACGCTGATGACCCAGTTTATGGAAACAGTGCAAAGTTGGTTTATAGTATATTGGAAGGGCAGCCTTATTTTTCCATTGAGC
CTGAAACAGCTATTATAAAAACTGCCCTTCCCAACATGGACAGAGAAGCCAAGGAGGAGTACCTGGTTGTTATCCAAGCCAAAGATATGG
GTGGACACTCTGGTGGCCTGTCTGGGACCACGACACTTACAGTGACTCTTACTGATGTTAATGACAATCCTCCAAAATTTGCACAGAGCC
TGTATCACTTCTCAGTACCGGAAGATGTGGTTCTTGGCACTGCAATAGGAAGGGTGAAGGCCAATGATCAGGATATTGGTGAAAATGCAC
AGTCATCATATGATATCATCGATGGAGATGGAACAGCACTTTTTGAAATCACTTCTGATGCCCAGGCCCAGGATGGCATTATAAGGCTAA
GAAAACCTCTGGACTTTGAGACCAAAAAATCCTATACGCTAAAGGTAGAGGCAGCCAATGTCCATATTGACCCACGCTTCAGTGGCAGGG
GGCCCTTTAAAGACACGGCGACAGTCAAAATCGTGGTTGAAGATGCTGATGAGCCTCCGGTCTTCTCTTCACCGACTTACCTACTTGAAG
TTCATGAAAATGCTGCTCTAAACTCCGTGATTGGGCAAGTGACTGCTCGTGACCCTGATATCACTTCCAGTCCTATAAGGTTTTCCATCG
ACCGGCACACTGACCTGGAGAGGCAGTTCAACATTAATGCAGACGATGGGAAGATAACGCTGGCAACACCACTTGACAGAGAATTAAGTG
TATGGCACAACATAACAATCATTGCTACTGAAATTAGGAACCACAGTCAGATATCACGAGTACCTGTTGCTATTAAAGTGCTGGATGTCA
ATGACAACGCCCCTGAATTCGCATCCGAATATGAGGCATTTTTATGTGAAAATGGAAAACCCGGCCAAGTCATTCAAACTGTTAGCGCCA
TGGACAAAGATGATCCCAAAAACGGACATTATTTCTTATACAGTCTCCTTCCAGAAATGGTCAACAATCCGAATTTCACCATCAAGAAAA
ATGAAGATAATTCCCTCAGTATTTTGGCAAAGCATAATGGATTCAACCGCCAGAAGCAAGAAGTCTATCTTTTACCAATCATAATCAGTG
ATAGTGGAAATCCTCCACTGAGCAGCACTAGCACCTTGACAATCAGGGTCTGTGGCTGCAGCAATGACGGTGTCGTCCAGTCTTGCAATG
TCGAAGCTTATGTCCTTCCAATTGGACTCAGTATGGGCGCCTTAATTGCCATATTAGCATGCATCATTTTGCTGTTAGTCATCGTGGTGC
TGTTTGTAACTCTACGGCGGCATAAAAATGAACCATTAATTATCAAAGATGATGAAGACGTTCGAGAAAACATCATTCGCTACGATGATG
AAGGAGGAGGGGAGGAGGACACAGAGGCTTTTGACATTGCAACTTTACAAAATCCAGATGGAATTAATGGATTTTTACCCCGTAAGGATA
TTAAACCAGATTTGCAGTTTATGCCAAGGCAAGGGCTTGCTCCAGTTCCAAATGGTGTTGATGTCGATGAATTTATAAATGTAAGGCTGC
ATGAGGCAGATAATGATCCCACGGCCCCGCCATATGACTCCATTCAGATATATGGCTATGAAGGCCGAGGGTCAGTGGCTGGCTCCCTCA
GCTCCTTGGAGTCCACCACATCAGACTCAGACCAGAATTTTGACTACCTCAGTGACTGGGGTCCCCGCTTTAAGAGACTGGGCGAACTCT
ACTCTGTTGGTGAAAGTGACAAAGAAACTTGACAGTGGATTATAAATAAATCACTGGAACTGAGCATTCTGTAATATTCTAGGGTCACTC
CCCTTAGATACAACCAATGTGGCTATTTGTTTTAGAGGCAAGTTTAGCACCAGTCATCTATAAACTCAACCACATTTTAATGTTGAACCA
AAAAAAGATAATAAAATAAAAAAGTATATGTTAGGAGGTTATAAATCTTGTGGAGTGTGAATTAAGTATGTGGAGTGTCTAGAAGTCCTT
GGATATTTGATATTTACCTGACCACCACAGACAAAGATTGGGATCCTGGCTAATCCTTAGATAAATGGTTTAAATAGAGGAAAAAATCAT
AATTAAAAGGTGCTTTCTTAGAAAAAAAAATACGGACCTGCAAGGAATCTGCTGCTGATATGTGTCTTCTGCAAGGATTTTTATGAATGC
AAATGGTTTTTTCCCCTTCACCAATAAGGATCCCGCCACAAATGATAAAGCAATACTTGGTCTGCTGTACATTATAACTTTTTGGAGTTT
TGAGAGGCCTCCTAGATTATACAGTACGGTGACCACACATTGTACATAATTGTTGGCCCCACTCACTAGAGACTGAATAGCATCTTTAAA
TATTGTGTCGAGCCTTAAAATATTCACATGTTCGTAATCCATTCCAGGGTGGGGCTTGCCAATTCAGTGGTGGGAGGAGAGAAATCCCAT
TCAAACATGCTTGTTTTCTAGAAGCAGGATTCCTCGTTCCCTCCTCTTCATCTTCTTCCACAAGGACACAAAGATAAACTGTATCACACA
GTGGACTACATAAGAGACAGATGGTTTTATTGCTAGCGCGTGAATTTATTTGTTTAATCCTCGAAATAAATATTTTATTGATGTCCATTA
ATGCTTTTATTTATTAAGGTCGGTAATCTATAGATTAAGGGGATATATGGGAAAAAACTAAATTATATCCATTAATAATCCTTTAGATTG
TTTTATATAAATATATATACAATGAATGTTTAATACATGTACATTTTGATGAGATGAGTATGGCAGGCAATATTATCGAAAGGAGAGCTA
ATAGTCTCTTTAGAGTAGAAAGTGTTATTGTAACTGGAGATGGCAGGAACAGCATCTTCCCAGACAAACTTTTGGACTGTTTTCTATTTT
GTTCATAATCCTAGTATTTGGTGTTTTTACTACAAGCACAAACATCCTAAAGTATATTGATTCCTGTGAATATTTAAACTCTAGACTTTT
AGATACCTACATCATGCCCTGCCCAATAAACATGCTTCAATTTACCCCCACAGTTTTAGAGCAGGAACTGATTTGTACATAATTTCACTG
TTTACGTTTTTAGCACTCCTATCCCTGATCTTCATGGTGATGCACAGAATGTCTTAGACTCCAAAAAGGAACAGCACTAGAAGATGTGAG
CATATTTAATTTGTAATGCAAACCTGCCATTTAGGAGTAGAAAATGTATGATAAAACTCAAGTATTACATGCAGATCATTTTAATTTTCT
ACTTTGCTTTAATGCAATATTGTTTATTCACTCCATGTATTGTATTCAGAGAAACTCCTGTATTGTTTCCTACTTTGTGAAATATATTTT
TATAAATACCTTTGTTGTCATTAATTTTTTTTTCAATCAGTGGAAGATCTATTAACAGAATCATCAACTCAAACTAAAATTCTAGAATAC
TCAACCAAATCATCCCAAGGGTCACTTTTGTTTGTAAGACTCTTTATTATAGAGAAACAGAGAAGAGAAATGGCTTGCCAGTGATCACAC
AGCAAGATACCAGCAGGGACATAAGAGGAACATGGAACACCTAAAGGCTAGTCCAGCTGTGTCATTTGGGTCCTTCTGGAAGCAGACGCA
TTGGGCAGGGAAAACCTTCAGACAAGTTTGCAGACCTAAAACTTGTAACAATAGAGGGATTGGGAGCAGGATTTGGCAAGAGAGTCTTAG
ACTGCAGTGCGGACCTGGCAAAATCTCTGCCAGTCTGACAGGGGGTTCTAGAGTGAAAACACATCCATTAAAGCAGTCAGGCTGTGGTCC
TCTGTCATCTCAGTCATTGGTGCGGGGCTGCTAAGAAGAGAACGGTTTTTGACTCAAAAGCTGAACGCACCAACTTCTAGAGGCCACCTT
CACTGTGACAGAAACTGCATGTTTAAATACTATACTAACAATTTATAACTATCCGGTGGCTTAATCAACTTTTTATTGAGTTTCTGTTGC
TGAGAATAAGTCATCTTTTATGCGTATTATTACGGCTAGTGAACACTTTTTCTTGAGGTCAAAGGGATGGTCCAACATGACTTTAAAATA
TACTAGGACTTGGCACAGTGTCTAAAACAAGTGCTTGGTGAATGTAAATTATTAGTAGTAGTTGCAGTAATAACCAATAGTAATATTCCA
ACTATCTTACACCTTCCAAACCAAGGAGAGATTATTATGTTTTATGTATCTCTTGAACACCAGACTCATTTCTAGTGTACTTTGAAGTGC
CCAAAGATTATAGACACACAAATATGTCTAACAGAATAATTACAGTATTTTTTAAGGAGTATAAAATCTGTATCCTCAAATATTGGTAAT
CAACAGGATAATCTTCGTACAGTGGTTTCTGTGAGCAGGAGATAATGTCTGCTCTACTAGTTGCCCAAATATCGCCTAAGTATTCTCTTT
GCCTAGGAACACAGAATGAAAGCTTGCATCTCTTGCTGACTTTCTTTGCCACCACAGTGTCAGCATTTTGTGTTTAAAAGCCTATTTCAG
GTCTTGTAACATAGAATAAAGTGACTAATACCTTGATCCTAATAAGATTGACCTATACTTTTAGAGTGTCATGAATTAAACTAAAAATCT
CAGGAACTATCTCTCTCTTTCTCTCTTTCTCTCTCTCTCTCTCTCTCTCTCTCACACACACACACACACACACACACACACACACACAAC
AAACAAATAAAAAACACACATTTTGACTTGAAGTTTTACTTTAGCAATAGACTTGCCAGGACTTTCCCAACCAAAAGATATCAATAAGGT
TCCTAACATTTTCTAAGATTTAAGTATCCCATGCTCAATTTGTTAAATAACACATTTTAAAAACTTTATTGAAATGACTATATTTTTAAA
GCTATGTGCATTGTTGTCTGTTTCATCAACATTGACATAGCAGAAACAAGAGTACTCTCTGCTAAATAGAGAAGAATGATTAAGTTGGAG
CCAAGTGAGACAAAGTTATCTCCCTCTGCCTACCTCACAATTCAAGGTTCCCACCTAGGGAACTGATGCATCCCTGGGTGATTGGACACA
ACATGGGATCAATTCAGCCTCTACTCTGCCTATGATTTGATCAAATCATATTAGCAAAGTGTCTCTTAAACATCCATATATGAATATTAA
AGAGTATTAAGGGGGGCATTTCTTAACAATATTTTTATGAGTATAGTTATAAGTTTCTAAACATTTATAATACGATGACTAAAATATGCT
ATTTTTAAATTCAAGTGTTAACCTTGCCACACAGAATTATGACTTCTAGGGTGTAAACTTTAAAGTGAAACTGTTTTGAAAAAAATCTGC
AGTTAAGTGTATGTGTATATATAGAAGAAAAGGAAACTTAGATTTACTGGTATCACCAGTGAAGCAAGAATGCTTAGAAAGATACAAATG
TGTCTTTGGGAGAGTCTGCTTAATCAGATGCTTAAAGTAAGACAAGTCTCTGCATGAGACTTAGAAATCTCCTAGGAGCAGCTGGATTCC
ACACTGAGACTCAACAGAGTTCTGGGCTATGCTGTATTTTGGAAAAGGAAAAGCGGGTGCTGAGAGCTAAGTAGCCAATTACTCTTTATA
GCCACATAAGGACTGAAGGCAAGTAGGCCCTTCCAACAAGTTGTATTATGCGATCACTGGCTTTGCAGGGAATCTCACGAATGTATAACC
TTCTGATTGCCTTTTTGATTGAAAGTTCCATCTGAGATCAGGGCAGTGTAACCAGTAATAAGATTTCAAAAAAATCCCATCACTGGCACT
GTCGGAAAGGCTGAGCATGACTGAAATCCTATCATTGTCAGTCAAAAAGATAAGGTAACAGCGGGCATCACTATAAAAGCTCTATAAATG
CACAACTTAAACATGAATATCAACATTAAAAAGAATATATATATCCTTATACATATATTTATAAATATATTCATATATATAAATATGCAC
ATATATACACAATTCAGTTACTGGGGATAATTTATAGTTTTAATTTTTCATCTCATAATCTCACGCACTGCCAACAAATTGAAATTGTGG
CTCTCTGTTTTCATGAATCTAACCTTGAATTTGAAAGAAGTTGAATTGAGGGTAAAGGGTTTTAAAAGCAGCTTTTTATTTGTGAACAGA
ATAATGGCTCATAATACCTGGGATTAGAATTAAATATGTCACGTTGTGAGGCTGTACTTAGACTTTTTAAATGTCATTGTATTTTTTTGT
GGACAAAATAATTGTAGAATATACTTTGCAGGAAATACTTTTCTATATTTTTTCAATTTCAATACTGTTTTATTTGCTATAAAAAGTGTC
TTTGCACTGTTACTCAGCCAAACAGTGTTGAATGTATTATTTGCCCTTGTAATTATTGCTTCTTATGATAATTGTAGAAGAGCATGTCTT
TATGATCTATCATTTAAAAATACATTTATTGTCATTGTAGTTTTAGTCAACACAAATTTATGGATTACATGGTATACTGTTGCTATTGAA
GATATTCTAGTCCTAGTATTTTGAGCACAGACCTAGCGTTATGGAGGACATAAAATTTAAAAATTTCCTGACTTGATGGACTATCTGAGG
AAAAAGAATTTTGTCTGTCACATTTATTGAGTATCTATCAGTACAGAAATTAAGCTACATGGTTGATACAGAAAGATTAAATACAGTAGC
ATTCTCAAACTTATTTTCTTTATTTATAAAATGTACCTAATCAATCTCATAAGAACTAATTGTTGAATTTTTTTTTTATCTATGGATAAA
TACTATTTGAGTCTGGGTTTAAGTTTGGTTGATCTGACACTAAATCCCCTTAACTTTCAACTAAACAGTTATCTCTGTAATTATGAGACT
TTTGATGATAAGAAATAGAAACTAAGTTATATATAGTGCTATGGAAGTACTGAGGAGGAAGTAAGGGACCCCATATGGGAAGACTCAAGA
AGACGTCACGGTGAAATTTTCCAAAAAGATGGGAACTCAAGAATGGGTGCAACAGAAATCACAGCTTTTCCAAATACTAAAAGGGAAAAT
TATAAAAAGCACCAATGGCACACTTTTGGACATTCAGAAAGATCCAGAAATTAGGTGCTTATAGGAAACTCTAGGTTTGCCAAATTGTAG
TGTTTTATGGATAGGAAAAATGAAGTTCAGAAACGTTATAAGGAATTTTCAGGGTTAAATTACACATCAAATATGTGAGAGAAACAGAAA
TTACATGCTGGTATTTGGGGTCATCTCCTGAGTTGTAATGTTGTAAGTGTTTTTGTATGTATTCTCCTCCTTCCTTTATGTGTGGAAGTT
TCATCTAGGTCTCAAGGTTAGTAGGCATTTGCTGGTGAAAATAGTGCCTTTGGGTACTATTTCCCCAACTTGAGTTACCTGCCACCATCT
AATTCACATCTTGAATGCAAGTATTATTTCTTGCAAGTATCCCTACTAATAGATAATAGATATTTCTATTATTATCCACAGATTACAGAA
GAGGGTTGCTAGGAGGAATATCACAAGATGCTGTCTGAAGAGAAAGACTGTGGAAAACCATGGCTTCAATGAACTCAGAGGTCAGGACCA
GAAAAGGAAATGAGAGGTCACCAAAGCCAAATGTTAATTTCTTGGGATTTCTTCTGTACATGCAAAGAACTTCAGGCCATCCTATGATTC
CTCAAAAATAAGAGGAAAATTTTAACAATTATGCTCTAAGATGGACCATGACAATTTAGGAGTCATTGGGATCACCCCCCAAAGCCAAAT
GTTAATTTCTTGGGATTTCTTCTGTACATGCAAAGAACTTCAGGCCATCCTATGATCCCTCACAAATAAGAGGAAGATTTTAACAATTAT
GCTCTAAGATGGAACATGACAATTTAGGAGTCACTGGGATCACCCCCCCCACCTTTCCAACGTTACTCTGCTTTAACTACAAATATGTCG
AATGGTTTTCTAATTTTTCTTTAACTTAACCTCTAAAGTTCGAGAGCTGTCATCTTTGTCAAGTCTGATTGTTGAGTATGTGAATGGATG
TTTTTGGCTCAATGTTAGAGCCAAAATTTATAAATAATAATTATTTATACATAATGATATTGCAAATAAACTTTAAGAAAGAGCTTTAAA

>In-frame_ENST00000413366_ENST00000577390_TCGA-AC-A5XU-01A_PRKCA_chr17_64685165_+_CDH8_chr16_61935377_length(amino acids)=1025AA_start in transcript=14_stop in transcript=3091
MGGTMADVFPGNDSTASQDVANRFARKGALRQKNVHEVKDHKFIARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHEFVTFSC
PGADKGPDTDDPRSKHKFKIHTYGSPTFCDHCGSLLYGLIHQGMKCDTCDMNVHKQCVINVPSLCGMDHTEKRGRIYLKAEVADEKLHVT
VRDAKNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNESFTFKLKPSDKDRRLSVEIWDWDRTTRNDFMGSLSFGVSEL
MKMPASGWYKLLNQEEGEYYNVPIPEGDEEGNMELRQKFELHTDLDPGSKKIKYILSGDGAGTIFQINDVTGDIHAIKRLDREEKAEYTL
TAQAVDWETSKPLEPPSEFIIKVQDINDNAPEFLNGPYHATVPEMSILGTSVTNVTATDADDPVYGNSAKLVYSILEGQPYFSIEPETAI
IKTALPNMDREAKEEYLVVIQAKDMGGHSGGLSGTTTLTVTLTDVNDNPPKFAQSLYHFSVPEDVVLGTAIGRVKANDQDIGENAQSSYD
IIDGDGTALFEITSDAQAQDGIIRLRKPLDFETKKSYTLKVEAANVHIDPRFSGRGPFKDTATVKIVVEDADEPPVFSSPTYLLEVHENA
ALNSVIGQVTARDPDITSSPIRFSIDRHTDLERQFNINADDGKITLATPLDRELSVWHNITIIATEIRNHSQISRVPVAIKVLDVNDNAP
EFASEYEAFLCENGKPGQVIQTVSAMDKDDPKNGHYFLYSLLPEMVNNPNFTIKKNEDNSLSILAKHNGFNRQKQEVYLLPIIISDSGNP
PLSSTSTLTIRVCGCSNDGVVQSCNVEAYVLPIGLSMGALIAILACIILLLVIVVLFVTLRRHKNEPLIIKDDEDVRENIIRYDDEGGGE
EDTEAFDIATLQNPDGINGFLPRKDIKPDLQFMPRQGLAPVPNGVDVDEFINVRLHEADNDPTAPPYDSIQIYGYEGRGSVAGSLSSLES

--------------------------------------------------------------
>In-frame_ENST00000413366_ENST00000584337_TCGA-AC-A5XU-01A_PRKCA_chr17_64685165_+_CDH8_chr16_61935377_length(transcript)=4156nt_BP=944nt
GAGGCAAGAGGTGGTTGGGGGGGACCATGGCTGACGTTTTCCCGGGCAACGACTCCACGGCGTCTCAGGACGTGGCCAACCGCTTCGCCC
GCAAAGGGGCGCTGAGGCAGAAGAACGTGCACGAGGTGAAGGACCACAAATTCATCGCGCGCTTCTTCAAGCAGCCCACCTTCTGCAGCC
ACTGCACCGACTTCATCTGGGGGTTTGGGAAACAAGGCTTCCAGTGCCAAGTTTGCTGTTTTGTGGTCCACAAGAGGTGCCATGAATTTG
TTACTTTTTCTTGTCCGGGTGCGGATAAGGGACCCGACACTGATGACCCCAGGAGCAAGCACAAGTTCAAAATCCACACTTACGGAAGCC
CCACCTTCTGCGATCACTGTGGGTCACTGCTCTATGGACTTATCCATCAAGGGATGAAATGTGACACCTGCGATATGAACGTTCACAAGC
AATGCGTCATCAATGTCCCCAGCCTCTGCGGAATGGATCACACTGAGAAGAGGGGGCGGATTTACCTAAAGGCTGAGGTTGCTGATGAAA
AGCTCCATGTCACAGTACGAGATGCAAAAAATCTAATCCCTATGGATCCAAACGGGCTTTCAGATCCTTATGTGAAGCTGAAACTTATTC
CTGATCCCAAGAATGAAAGCAAGCAAAAAACCAAAACCATCCGCTCCACACTAAATCCGCAGTGGAATGAGTCCTTTACATTCAAATTGA
AACCTTCAGACAAAGACCGACGACTGTCTGTAGAAATCTGGGACTGGGATCGAACAACAAGGAATGACTTCATGGGATCCCTTTCCTTTG
GAGTTTCGGAGCTGATGAAGATGCCGGCCAGTGGATGGTACAAGTTGCTTAACCAAGAAGAAGGTGAGTACTACAACGTACCCATTCCGG
AAGGGGACGAGGAAGGAAACATGGAACTCAGGCAGAAATTCGAGCTACACACAGACCTGGATCCTGGGAGCAAAAAAATCAAGTATATCC
TATCAGGTGATGGAGCTGGGACCATATTTCAAATAAATGATGTAACTGGAGATATCCATGCTATAAAAAGACTTGACCGGGAGGAAAAGG
CTGAGTATACCCTAACAGCTCAAGCAGTGGACTGGGAGACAAGCAAACCTCTGGAGCCTCCTTCTGAATTTATTATTAAAGTTCAAGACA
TCAATGACAATGCACCAGAGTTTCTTAATGGACCCTATCATGCTACTGTGCCAGAAATGTCCATTTTGGGTACATCTGTCACTAACGTCA
CTGCGACCGACGCTGATGACCCAGTTTATGGAAACAGTGCAAAGTTGGTTTATAGTATATTGGAAGGGCAGCCTTATTTTTCCATTGAGC
CTGAAACAGCTATTATAAAAACTGCCCTTCCCAACATGGACAGAGAAGCCAAGGAGGAGTACCTGGTTGTTATCCAAGCCAAAGATATGG
GTGGACACTCTGGTGGCCTGTCTGGGACCACGACACTTACAGTGACTCTTACTGATGTTAATGACAATCCTCCAAAATTTGCACAGAGCC
TGTATCACTTCTCAGTACCGGAAGATGTGGTTCTTGGCACTGCAATAGGAAGGGTGAAGGCCAATGATCAGGATATTGGTGAAAATGCAC
AGTCATCATATGATATCATCGATGGAGATGGAACAGCACTTTTTGAAATCACTTCTGATGCCCAGGCCCAGGATGGCATTATAAGGCTAA
GAAAACCTCTGGACTTTGAGACCAAAAAATCCTATACGCTAAAGGTAGAGGCAGCCAATGTCCATATTGACCCACGCTTCAGTGGCAGGG
GGCCCTTTAAAGACACGGCGACAGTCAAAATCGTGGTTGAAGATGCTGATGAGCCTCCGGTCTTCTCTTCACCGACTTACCTACTTGAAG
TTCATGAAAATGCTGCTCTAAACTCCGTGATTGGGCAAGTGACTGCTCGTGACCCTGATATCACTTCCAGTCCTATAAGGTTTTCCATCG
ACCGGCACACTGACCTGGAGAGGCAGTTCAACATTAATGCAGACGATGGGAAGATAACGCTGGCAACACCACTTGACAGAGAATTAAGTG
TATGGCACAACATAACAATCATTGCTACTGAAATTAGGAACCACAGTCAGATATCACGAGTACCTGTTGCTATTAAAGTGCTGGATGTCA
ATGACAACGCCCCTGAATTCGCATCCGAATATGAGGCATTTTTATGTGAAAATGGAAAACCCGGCCAAGTAAATATCTCCATGTTGTTAA
TGCTGAATATGTTTGTATACAACTGTCTCATATTTGACTAACCTGCATTATATTGTGCATTTGCATCATTTATGATCTGCAAAGTCTCAG
GCAAGAAACACATCCAAATGGGAACAGAGAGGGAATTTTTTTTCTCCATCAGATGTTATTTCTCTTCCTACTTATGACCAAATTGGCTCC
TAAAGTGGAACAACCTGCTGTGCCACAAACCCAGAGCCAAATCACTGTCTTAAAATATCTTGGGATATGGATGATAGCAGGAGATGTCTT
AGAGTGACGGGGGCTGAATTTTTACTTTCAAATGACAAGAAGCAAGGTAAAACCTCGTGGAGAGGAGACATTTGTTTCACAGCAAACATA
TGAATACCAAATAATAGTGAAACCCAAGAAGGCCAGTGGTTTATAGAAAGTTGTAGGAAGTGAATATTGAAATCTGTAAATATGTAAATA
TATTTAGATAAACATAAGATGAACAACACGTTTTACATGTGTGTATTAGTAGAACATTTTTTGTGCCTCATATTGCATAGATGGGTCAAT
GAAAACAGAAAAAAAAGAAACATAAAGAAAGTGAGAGAGAGGGAGAAGGAAAGGGAGAGGGAGAGGGAATGGGAATGGGAGTGGGAGGAA
GGGAGGGAGGGAGAGAGAAAAAGAGGGAGGAAGAAAGGGAGGAAAATAGTTAAACAAGCAAGATGAACAGAAACAAATATCTGCTATACT
CTGAATGTCAAAATGGAAATAGCCTGTGTAAAGTTCTGCAAAACCATAAATGTAATAGATTTATTTTAACAAGGTACCAAAGTACTGTAT
GTTTAAGAAATTTATCATTTTTCAACTTCCTAATTTATTTCTGGATGGTGACATTTTAATTTAAATAAACAGCAGCTGACAGTATGACAC
TGGAGTTGTTAATCCAACTATTCTTGTGCCTCATGTGGGTGTTAGGAATTAAACTTACTATTTGCTAAGCAGCTTACCTGACAAGAGTCA
GATTTTTTCCCCCTAAAGAAAGGACTGGCACTGTAGCTGTATGCTTTATTATAAATGATCAATTTGTTACCCTCCTATAAAACAGTGGGC
ATTTCTCCGTAGACTACTCTCATGTATCTGGAGAATTAGCATTGTTTCCATCTACCAGAATAAGACACACCACACCACACACACACACAC
GCACACACACACACACGTTAAAGCTAAAATTCTAATAATAAAACTGATTAACTTTTAAACATCTAGCCATGTTCTCATCAAAGCATTCAG
CTTTAGTAGAGATATAGGTTTATTTTTATAATATTCTAACATTAGCTTAAATGTTTCCTAATTTTATCATGTGGAATTACCCCCTATCAA
TCACACGTTTTGAGCATCTTCATTTGTGATCCTTTGAGAAGGGAGTGTGTATATGTTTATATATACACATATCAATACATATCATTTACC
TAAATTGGTAGATTGAGTTGTCAGAGAGAGTTTGATCAAAATATGGCAGGTTGTTTCAAAGATATGGTTGTTGTGTGGACCAGATCATTG
CTGAGATAATGTAGCCAAATCACAGACTGGTAAGCTAGACTTTTTCAATCACATAGAGTCTGTAAAATACTTCAGAATTTAAATAAAACT
CCATTGCTCATGCAAAACTCATCAGATAAGTTCAAGGAGTCAATGACATTGATATTTCAAAAACTCAACATTGGCTTCACTTGCGTTATT
GACAAGCATGTTTCTTGGATCTCTGGGAATTTGTAGGTTTGCCCTGTGGATTTTGACTGTTTTCAAAGTTCTAATGATTTCTCAGTCGTT
CTTCTTAACTTCAGAAAAAAAAATGCATTGTTTTCTCATCTTTCCTATGCAAAACCAAAATAAAAAATTGATTCTTTGTTTTATGATTTT

>In-frame_ENST00000413366_ENST00000584337_TCGA-AC-A5XU-01A_PRKCA_chr17_64685165_+_CDH8_chr16_61935377_length(amino acids)=758AA_start in transcript=14_stop in transcript=2290
MGGTMADVFPGNDSTASQDVANRFARKGALRQKNVHEVKDHKFIARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHEFVTFSC
PGADKGPDTDDPRSKHKFKIHTYGSPTFCDHCGSLLYGLIHQGMKCDTCDMNVHKQCVINVPSLCGMDHTEKRGRIYLKAEVADEKLHVT
VRDAKNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNESFTFKLKPSDKDRRLSVEIWDWDRTTRNDFMGSLSFGVSEL
MKMPASGWYKLLNQEEGEYYNVPIPEGDEEGNMELRQKFELHTDLDPGSKKIKYILSGDGAGTIFQINDVTGDIHAIKRLDREEKAEYTL
TAQAVDWETSKPLEPPSEFIIKVQDINDNAPEFLNGPYHATVPEMSILGTSVTNVTATDADDPVYGNSAKLVYSILEGQPYFSIEPETAI
IKTALPNMDREAKEEYLVVIQAKDMGGHSGGLSGTTTLTVTLTDVNDNPPKFAQSLYHFSVPEDVVLGTAIGRVKANDQDIGENAQSSYD
IIDGDGTALFEITSDAQAQDGIIRLRKPLDFETKKSYTLKVEAANVHIDPRFSGRGPFKDTATVKIVVEDADEPPVFSSPTYLLEVHENA
ALNSVIGQVTARDPDITSSPIRFSIDRHTDLERQFNINADDGKITLATPLDRELSVWHNITIIATEIRNHSQISRVPVAIKVLDVNDNAP

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Fusion Gene PPI Analysis for PRKCA-CDH8


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for PRKCA-CDH8


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for PRKCA-CDH8


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgenePRKCAC0036341Schizophrenia2PSYGENET
HgenePRKCAC0002152Alloxan Diabetes1CTD_human
HgenePRKCAC0011853Diabetes Mellitus, Experimental1CTD_human
HgenePRKCAC0018800Cardiomegaly1CTD_human
HgenePRKCAC0021841Intestinal Neoplasms1CTD_human
HgenePRKCAC0032617Polyuria1CTD_human
HgenePRKCAC0033975Psychotic Disorders1PSYGENET
HgenePRKCAC0036337Schizoaffective Disorder1PSYGENET
HgenePRKCAC0038433Streptozotocin Diabetes1CTD_human
HgenePRKCAC0162283Nephrogenic Diabetes Insipidus1CTD_human
HgenePRKCAC0264423Asthma, Occupational1CTD_human
HgenePRKCAC0268443Acquired Nephrogenic Diabetes Insipidus1CTD_human
HgenePRKCAC0346627Intestinal Cancer1CTD_human
HgenePRKCAC0349204Nonorganic psychosis1PSYGENET
HgenePRKCAC0400966Non-alcoholic Fatty Liver Disease1CTD_human
HgenePRKCAC0677501Congenital Nephrogenic Diabetes Insipidus1CTD_human
HgenePRKCAC1383860Cardiac Hypertrophy1CTD_human
HgenePRKCAC1563705Nephrogenic Diabetes Insipidus, Type I1CTD_human
HgenePRKCAC1563706Nephrogenic Diabetes Insipidus, Type II1CTD_human
HgenePRKCAC3241937Nonalcoholic Steatohepatitis1CTD_human
HgenePRKCAC3542500ADH-Resistant Diabetes Insipidus1CTD_human
TgeneCDH8C0001973Alcoholic Intoxication, Chronic1PSYGENET