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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:PRMT7-EXOC4 (FusionGDB2 ID:68509) |
Fusion Gene Summary for PRMT7-EXOC4 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: PRMT7-EXOC4 | Fusion gene ID: 68509 | Hgene | Tgene | Gene symbol | PRMT7 | EXOC4 | Gene ID | 54496 | 60412 |
| Gene name | protein arginine methyltransferase 7 | exocyst complex component 4 | |
| Synonyms | SBIDDS | SEC8|SEC8L1|Sec8p | |
| Cytomap | 16q22.1 | 7q33 | |
| Type of gene | protein-coding | protein-coding | |
| Description | protein arginine N-methyltransferase 7[Myelin basic protein]-arginine N-methyltransferase PRMT7histone-arginine N-methyltransferase PRMT7 | exocyst complex component 4SEC8-like 1exocyst complex component Sec8 | |
| Modification date | 20200320 | 20200320 | |
| UniProtAcc | . | Q96A65 | |
| Ensembl transtripts involved in fusion gene | ENST00000449359, ENST00000564441, ENST00000441236, ENST00000348497, ENST00000339507, | ENST00000253861, ENST00000539845, ENST00000393161, ENST00000545148, ENST00000460346, ENST00000541309, | |
| Fusion gene scores | * DoF score | 4 X 5 X 4=80 | 35 X 25 X 10=8750 |
| # samples | 4 | 39 | |
| ** MAII score | log2(4/80*10)=-1 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(39/8750*10)=-4.48773698785744 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: PRMT7 [Title/Abstract] AND EXOC4 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | PRMT7(68380183)-EXOC4(133580352), # samples:2 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | PRMT7 | GO:0016571 | histone methylation | 15494416 |
| Hgene | PRMT7 | GO:0018216 | peptidyl-arginine methylation | 15044439 |
| Fusion gene breakpoints across PRMT7 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
| Fusion gene breakpoints across EXOC4 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | SARC | TCGA-DX-A7EF-01A | PRMT7 | chr16 | 68380183 | + | EXOC4 | chr7 | 133580352 | + |
| ChimerDB4 | SARC | TCGA-DX-A7EF-01A | PRMT7 | chr16 | 68380183 | - | EXOC4 | chr7 | 133580352 | + |
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Fusion Gene ORF analysis for PRMT7-EXOC4 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000449359 | ENST00000253861 | PRMT7 | chr16 | 68380183 | + | EXOC4 | chr7 | 133580352 | + |
| In-frame | ENST00000449359 | ENST00000539845 | PRMT7 | chr16 | 68380183 | + | EXOC4 | chr7 | 133580352 | + |
| 5CDS-intron | ENST00000449359 | ENST00000393161 | PRMT7 | chr16 | 68380183 | + | EXOC4 | chr7 | 133580352 | + |
| 5CDS-intron | ENST00000449359 | ENST00000545148 | PRMT7 | chr16 | 68380183 | + | EXOC4 | chr7 | 133580352 | + |
| 5CDS-3UTR | ENST00000449359 | ENST00000460346 | PRMT7 | chr16 | 68380183 | + | EXOC4 | chr7 | 133580352 | + |
| 5CDS-intron | ENST00000449359 | ENST00000541309 | PRMT7 | chr16 | 68380183 | + | EXOC4 | chr7 | 133580352 | + |
| intron-3CDS | ENST00000564441 | ENST00000253861 | PRMT7 | chr16 | 68380183 | + | EXOC4 | chr7 | 133580352 | + |
| intron-3CDS | ENST00000564441 | ENST00000539845 | PRMT7 | chr16 | 68380183 | + | EXOC4 | chr7 | 133580352 | + |
| intron-intron | ENST00000564441 | ENST00000393161 | PRMT7 | chr16 | 68380183 | + | EXOC4 | chr7 | 133580352 | + |
| intron-intron | ENST00000564441 | ENST00000545148 | PRMT7 | chr16 | 68380183 | + | EXOC4 | chr7 | 133580352 | + |
| intron-3UTR | ENST00000564441 | ENST00000460346 | PRMT7 | chr16 | 68380183 | + | EXOC4 | chr7 | 133580352 | + |
| intron-intron | ENST00000564441 | ENST00000541309 | PRMT7 | chr16 | 68380183 | + | EXOC4 | chr7 | 133580352 | + |
| In-frame | ENST00000441236 | ENST00000253861 | PRMT7 | chr16 | 68380183 | + | EXOC4 | chr7 | 133580352 | + |
| In-frame | ENST00000441236 | ENST00000539845 | PRMT7 | chr16 | 68380183 | + | EXOC4 | chr7 | 133580352 | + |
| 5CDS-intron | ENST00000441236 | ENST00000393161 | PRMT7 | chr16 | 68380183 | + | EXOC4 | chr7 | 133580352 | + |
| 5CDS-intron | ENST00000441236 | ENST00000545148 | PRMT7 | chr16 | 68380183 | + | EXOC4 | chr7 | 133580352 | + |
| 5CDS-3UTR | ENST00000441236 | ENST00000460346 | PRMT7 | chr16 | 68380183 | + | EXOC4 | chr7 | 133580352 | + |
| 5CDS-intron | ENST00000441236 | ENST00000541309 | PRMT7 | chr16 | 68380183 | + | EXOC4 | chr7 | 133580352 | + |
| In-frame | ENST00000348497 | ENST00000253861 | PRMT7 | chr16 | 68380183 | + | EXOC4 | chr7 | 133580352 | + |
| In-frame | ENST00000348497 | ENST00000539845 | PRMT7 | chr16 | 68380183 | + | EXOC4 | chr7 | 133580352 | + |
| 5CDS-intron | ENST00000348497 | ENST00000393161 | PRMT7 | chr16 | 68380183 | + | EXOC4 | chr7 | 133580352 | + |
| 5CDS-intron | ENST00000348497 | ENST00000545148 | PRMT7 | chr16 | 68380183 | + | EXOC4 | chr7 | 133580352 | + |
| 5CDS-3UTR | ENST00000348497 | ENST00000460346 | PRMT7 | chr16 | 68380183 | + | EXOC4 | chr7 | 133580352 | + |
| 5CDS-intron | ENST00000348497 | ENST00000541309 | PRMT7 | chr16 | 68380183 | + | EXOC4 | chr7 | 133580352 | + |
| In-frame | ENST00000339507 | ENST00000253861 | PRMT7 | chr16 | 68380183 | + | EXOC4 | chr7 | 133580352 | + |
| In-frame | ENST00000339507 | ENST00000539845 | PRMT7 | chr16 | 68380183 | + | EXOC4 | chr7 | 133580352 | + |
| 5CDS-intron | ENST00000339507 | ENST00000393161 | PRMT7 | chr16 | 68380183 | + | EXOC4 | chr7 | 133580352 | + |
| 5CDS-intron | ENST00000339507 | ENST00000545148 | PRMT7 | chr16 | 68380183 | + | EXOC4 | chr7 | 133580352 | + |
| 5CDS-3UTR | ENST00000339507 | ENST00000460346 | PRMT7 | chr16 | 68380183 | + | EXOC4 | chr7 | 133580352 | + |
| 5CDS-intron | ENST00000339507 | ENST00000541309 | PRMT7 | chr16 | 68380183 | + | EXOC4 | chr7 | 133580352 | + |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000449359 | PRMT7 | chr16 | 68380183 | + | ENST00000253861 | EXOC4 | chr7 | 133580352 | + | 3590 | 1168 | 61 | 2358 | 765 |
| ENST00000449359 | PRMT7 | chr16 | 68380183 | + | ENST00000539845 | EXOC4 | chr7 | 133580352 | + | 2418 | 1168 | 61 | 2358 | 765 |
| ENST00000441236 | PRMT7 | chr16 | 68380183 | + | ENST00000253861 | EXOC4 | chr7 | 133580352 | + | 4295 | 1873 | 766 | 3063 | 765 |
| ENST00000441236 | PRMT7 | chr16 | 68380183 | + | ENST00000539845 | EXOC4 | chr7 | 133580352 | + | 3123 | 1873 | 766 | 3063 | 765 |
| ENST00000348497 | PRMT7 | chr16 | 68380183 | + | ENST00000253861 | EXOC4 | chr7 | 133580352 | + | 4223 | 1801 | 766 | 2991 | 741 |
| ENST00000348497 | PRMT7 | chr16 | 68380183 | + | ENST00000539845 | EXOC4 | chr7 | 133580352 | + | 3051 | 1801 | 766 | 2991 | 741 |
| ENST00000339507 | PRMT7 | chr16 | 68380183 | + | ENST00000253861 | EXOC4 | chr7 | 133580352 | + | 4443 | 2021 | 764 | 3211 | 815 |
| ENST00000339507 | PRMT7 | chr16 | 68380183 | + | ENST00000539845 | EXOC4 | chr7 | 133580352 | + | 3271 | 2021 | 764 | 3211 | 815 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000449359 | ENST00000253861 | PRMT7 | chr16 | 68380183 | + | EXOC4 | chr7 | 133580352 | + | 0.002868724 | 0.9971312 |
| ENST00000449359 | ENST00000539845 | PRMT7 | chr16 | 68380183 | + | EXOC4 | chr7 | 133580352 | + | 0.01093277 | 0.98906726 |
| ENST00000441236 | ENST00000253861 | PRMT7 | chr16 | 68380183 | + | EXOC4 | chr7 | 133580352 | + | 0.002816789 | 0.99718314 |
| ENST00000441236 | ENST00000539845 | PRMT7 | chr16 | 68380183 | + | EXOC4 | chr7 | 133580352 | + | 0.009519685 | 0.99048036 |
| ENST00000348497 | ENST00000253861 | PRMT7 | chr16 | 68380183 | + | EXOC4 | chr7 | 133580352 | + | 0.001876046 | 0.99812394 |
| ENST00000348497 | ENST00000539845 | PRMT7 | chr16 | 68380183 | + | EXOC4 | chr7 | 133580352 | + | 0.007518487 | 0.9924816 |
| ENST00000339507 | ENST00000253861 | PRMT7 | chr16 | 68380183 | + | EXOC4 | chr7 | 133580352 | + | 0.003184307 | 0.99681574 |
| ENST00000339507 | ENST00000539845 | PRMT7 | chr16 | 68380183 | + | EXOC4 | chr7 | 133580352 | + | 0.009334815 | 0.9906652 |
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Fusion Genomic Features for PRMT7-EXOC4 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| PRMT7 | chr16 | 68380183 | + | EXOC4 | chr7 | 133580351 | + | 2.35E-06 | 0.9999976 |
| PRMT7 | chr16 | 68380183 | + | EXOC4 | chr7 | 133580351 | + | 2.35E-06 | 0.9999976 |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for PRMT7-EXOC4 |
| Go to FGviewer for the breakpoints of chr16:68380183-chr7:133580352 - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | EXOC4 |
| FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes. | FUNCTION: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | PRMT7 | chr16:68380183 | chr7:133580352 | ENST00000339507 | + | 11 | 19 | 14_345 | 397.0 | 693.0 | Domain | SAM-dependent MTase PRMT-type 1 |
| Hgene | PRMT7 | chr16:68380183 | chr7:133580352 | ENST00000441236 | + | 10 | 18 | 14_345 | 347.0 | 643.0 | Domain | SAM-dependent MTase PRMT-type 1 |
| Hgene | PRMT7 | chr16:68380183 | chr7:133580352 | ENST00000449359 | + | 9 | 17 | 14_345 | 347.0 | 643.0 | Domain | SAM-dependent MTase PRMT-type 1 |
| Tgene | EXOC4 | chr16:68380183 | chr7:133580352 | ENST00000393161 | 0 | 10 | 32_114 | 0 | 474.0 | Coiled coil | Ontology_term=ECO:0000255 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | PRMT7 | chr16:68380183 | chr7:133580352 | ENST00000339507 | + | 11 | 19 | 358_684 | 397.0 | 693.0 | Domain | SAM-dependent MTase PRMT-type 2 |
| Hgene | PRMT7 | chr16:68380183 | chr7:133580352 | ENST00000348497 | + | 9 | 14 | 14_345 | 323.0 | 545.0 | Domain | SAM-dependent MTase PRMT-type 1 |
| Hgene | PRMT7 | chr16:68380183 | chr7:133580352 | ENST00000348497 | + | 9 | 14 | 358_684 | 323.0 | 545.0 | Domain | SAM-dependent MTase PRMT-type 2 |
| Hgene | PRMT7 | chr16:68380183 | chr7:133580352 | ENST00000441236 | + | 10 | 18 | 358_684 | 347.0 | 643.0 | Domain | SAM-dependent MTase PRMT-type 2 |
| Hgene | PRMT7 | chr16:68380183 | chr7:133580352 | ENST00000449359 | + | 9 | 17 | 358_684 | 347.0 | 643.0 | Domain | SAM-dependent MTase PRMT-type 2 |
| Tgene | EXOC4 | chr16:68380183 | chr7:133580352 | ENST00000253861 | 10 | 18 | 32_114 | 578.0 | 975.0 | Coiled coil | Ontology_term=ECO:0000255 |
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Fusion Gene Sequence for PRMT7-EXOC4 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >In-frame_ENST00000449359_ENST00000253861_TCGA-DX-A7EF-01A_PRMT7_chr16_68380183_+_EXOC4_chr7_133580352_length(transcript)=3590nt_BP=1168nt AAAAGTGGTAGCAGCGGAGGCGAGCGGAGGGTTTCCCGCGGCGGATTTCTGACAGTCAGACTTGTCCACAAGAACTCAACTGGCAAGGCT GCTTTTCTGTGCTAAAACTGGGGAGCTAGTGGGCACCATGAAGATCTTCTGCAGTCGGGCCAATCCGACCACGGGGTCTGTGGAGTGGCT GGAGGAGGATGAACACTATGATTACCACCAGGAGATTGCAAGGTCATCTTATGCAGATATGCTACATGACAAAGACAGAGTTTTCAAGCC TATGGCTGATGCTGCTGTGAAGATTGTGGAGAAAAATGGCTTTAGTGATAAGATTAAGGTTATCAACAAGCATTCCACCGAGGTGACTGT AGGTCCAGAGGGTGACATGCCATGCCGTGCCAACATCCTGGTCACAGAGTTGTTTGACACAGAGCTGATCGGGGAGGGGGCGCTGCCCTC CTATGAGCACGCACACAGGCATCTCGTGGAGGAAAATTGTGAGGCCGTGCCCCACAGAGCCACCGTCTATGCACAGCTGGTGGAGTCCGG GAGGATGTGGTCGTGGAACAAGCTATTTCCCATCCACGTGCAGACCAGCCTCGGAGAGCAGGTCATCGTCCCTCCCGTTGACGTGGAGAG CTGCCCTGGCGCACCCTCTGTCTGTGACATTCAGCTGAACCAGGTGTCACCAGCCGACTTTACAGTCCTCAGCGATGTGCTGCCCATGTT CAGCATAGACTTCAGCAAGCAAGTCAGTAGCTCAGCAGCCTGCCATAGCAGGCGGTTTGAACCTCTGACATCTGGCCGAGCTCAGGTGGT TCTCTCGTGGTGGGACATTGAAATGGACCCTGAGGGGAAGATCAAGTGCACCATGGCCCCCTTCTGGGCACACTCAGACCCAGAGGAGAT GCAGTGGCGGGACCACTGGATGCAGTGTGTGTACTTCCTGCCACAAGAGGAGCCTGTGGTGCAGGGCTCAGCGCTCTATCTGGTAGCCCA CCACGATGACTACTGCGTATGGTACAGCCTGCAGAGGACCAGCCCTGAAAAGAATGAGAGAGTCCGCCAGATGCGCCCCGTGTGTGACTG CCAGGCTCACCTGCTCTGGAACCGGCCTCGGTTTGGAGAGATCAATGACCAGGACAGAACTGATCGATACGTCCAGGCTCTGAGGACCAG CACAATCATTGTGGAGAAGACAGTTCAAGACCTCCTGAACCTGATGCATGACTTGAGTGCATATTCAGATCAATTCCTCAACATGGTGTG CGTGAAGCTCCAGGAGTACAAGGACACCTGCACTGCAGCTTACAGGGGTATTGTCCAGTCAGAAGAAAAACTTGTCATCAGTGCATCCTG GGCAAAAGATGATGATATCAGCAGACTCTTGAAATCTCTACCAAACTGGATGAATATGGCTCAACCCAAACAGCTGAGGCCAAAAAGAGA GGAGGAAGAAGATTTCATAAGGGCAGCTTTTGGCAAGGAGTCTGAAGTTCTTATTGGGAACCTGGGTGATAAATTAATCCCTCCACAAGA CATCCTTCGTGACGTCAGTGACCTCAAAGCCTTGGCCAACATGCATGAAAGCCTGGAATGGTTGGCAAGTCGAACAAAGTCAGCTTTCTC CAATCTTTCTACATCCCAGATGCTTTCTCCTGCTCAAGACAGCCACACGAACACGGATCTCCCCCCAGTGTCAGAGCAGATCATGCAGAC TCTCAGTGAACTTGCCAAATCGTTCCAGGATATGGCTGACCGCTGCTTGCTTGTCTTACATCTGGAAGTGAGGGTTCACTGTTTCCACTA TCTTATCCCTCTTGCAAAGGAGGGGAACTATGCCATTGTGGCTAATGTGGAAAGTATGGATTATGACCCCCTGGTGGTCAAGCTCAACAA AGATATCAGCGCCATTGAAGAGGCCATGAGCGCCAGCCTTCAGCAGCACAAGTTCCAGTATATCTTCGAAGGCCTGGGCCACCTGATCTC CTGCATCCTCATTAATGGTGCCCAGTACTTCAGGCGCATCAGTGAGTCTGGCATCAAGAAAATGTGTAGGAACATTTTTGTTCTTCAGCA GAATTTGACCAACATCACCATGTCGCGGGAGGCAGACCTGGACTTTGCAAGGCAGTACTACGAGATGCTTTACAACACAGCTGACGAGCT CCTGAACCTGGTGGTGGACCAGGGTGTGAAGTACACGGAGCTGGAGTACATCCACGCTCTGACCCTGCTGCACCGCAGCCAGACTGGGGT GGGGGAACTGACCACCCAGAACACGAGGCTGCAGAGGCTCAAAGAGATCATCTGCGAGCAGGCTGCCATCAAGCAAGCCACCAAGGACAA GAAGATAACTACCGTTTAGCAGGGCGTACTGCGGTTGGTGACGGGGGTCCCCTCAGTCACACTCACTTTTTTCCTTGGTATGTTATTGAG TATATTCTGAGCTTAGTTTTCTCTACAGTGATACTTTAGTGGAGAGGAGGTGTAAGGATTCTTTCTCTCTGGTTTTGGCTTTTCATATAA ATGCTAAAGGAAGGCGACAGTACAGAGTGTTTTGGTTGAACAACTACTTTAATGCAGTCAAATCTAACGGGACTAGGGTGGGATAGGGAG GAAGGTGGTATCAAATTGTTGGACTCTGAAAAACAAGTGGATGGATTACTAATATTTGATTTATTACTCAATATATATATAATTCCAGCC TTGGAAAGTAGGAAAGTAGGCTGCTACCTAACTTTTAGTCCCTTCCAAAACCATTTAGTAGGGTTCTATTACATAAACAGTAGGGTTTTT CCTCTCCTGACCTTATCCGTTTACAGTTCAATGAAATAAGTGTATGTGCATTGCTGTCTGTCTCTATTGCCAAAATCAAATAAATGGCTT CTCAGCTGCTGTTTACAACAAACTTCCCTAACCAAAACAGAACCTCTAATTTAGGGCTAGGAATAGAAGTCTTTTGATCCCAGTCCCTGG GACAGTTTTGTATGCTGTATCTTGTACACAGGTTGTAGGTTGGTTTATTGCCATTTTGTTTTATTTCTGCTGTATAAAAACCAAGAGCCA GACAATTAGACAACTATGGAGGAATGAAAGGCAATTCAAACATCTGCTTGATTCCCGCCCCGCCACCCCTAATTTCTGAGAGAATAATGG TTAGAGAACATTGCATCTCACTTGAAACATCCTTTGGGGGTAAATGATTCTTAGGTGCTCACTTGGTCTGAGCTCAGCTGAATGCAGGGA AGATGGGACAGAGTGACATTTCTCCTCTGTGCGGCCTCCAGCTGAGCCTGTCTCTGAATTGTTCCCTCCCCCGCAATGTGGGCACTTACC ATGTTCCTGGCACACTGGACCTCACCATGTCCCCCGGTCACCAGTCCTCTTGCTGCCCATGGTTCATAGGTCATAGAAGGCAGCAATGCA CTGACTGGGCCACATCTTGAAAACTCGTGGAAAGGGAAAGGGGAGGAGATGGGACTTTGACCACACACAGTGATGCCTCACACCCTGAAG >In-frame_ENST00000449359_ENST00000253861_TCGA-DX-A7EF-01A_PRMT7_chr16_68380183_+_EXOC4_chr7_133580352_length(amino acids)=765AA_start in transcript=61_stop in transcript=2358 MSTRTQLARLLFCAKTGELVGTMKIFCSRANPTTGSVEWLEEDEHYDYHQEIARSSYADMLHDKDRVFKPMADAAVKIVEKNGFSDKIKV INKHSTEVTVGPEGDMPCRANILVTELFDTELIGEGALPSYEHAHRHLVEENCEAVPHRATVYAQLVESGRMWSWNKLFPIHVQTSLGEQ VIVPPVDVESCPGAPSVCDIQLNQVSPADFTVLSDVLPMFSIDFSKQVSSSAACHSRRFEPLTSGRAQVVLSWWDIEMDPEGKIKCTMAP FWAHSDPEEMQWRDHWMQCVYFLPQEEPVVQGSALYLVAHHDDYCVWYSLQRTSPEKNERVRQMRPVCDCQAHLLWNRPRFGEINDQDRT DRYVQALRTSTIIVEKTVQDLLNLMHDLSAYSDQFLNMVCVKLQEYKDTCTAAYRGIVQSEEKLVISASWAKDDDISRLLKSLPNWMNMA QPKQLRPKREEEEDFIRAAFGKESEVLIGNLGDKLIPPQDILRDVSDLKALANMHESLEWLASRTKSAFSNLSTSQMLSPAQDSHTNTDL PPVSEQIMQTLSELAKSFQDMADRCLLVLHLEVRVHCFHYLIPLAKEGNYAIVANVESMDYDPLVVKLNKDISAIEEAMSASLQQHKFQY IFEGLGHLISCILINGAQYFRRISESGIKKMCRNIFVLQQNLTNITMSREADLDFARQYYEMLYNTADELLNLVVDQGVKYTELEYIHAL -------------------------------------------------------------- >In-frame_ENST00000449359_ENST00000539845_TCGA-DX-A7EF-01A_PRMT7_chr16_68380183_+_EXOC4_chr7_133580352_length(transcript)=2418nt_BP=1168nt AAAAGTGGTAGCAGCGGAGGCGAGCGGAGGGTTTCCCGCGGCGGATTTCTGACAGTCAGACTTGTCCACAAGAACTCAACTGGCAAGGCT GCTTTTCTGTGCTAAAACTGGGGAGCTAGTGGGCACCATGAAGATCTTCTGCAGTCGGGCCAATCCGACCACGGGGTCTGTGGAGTGGCT GGAGGAGGATGAACACTATGATTACCACCAGGAGATTGCAAGGTCATCTTATGCAGATATGCTACATGACAAAGACAGAGTTTTCAAGCC TATGGCTGATGCTGCTGTGAAGATTGTGGAGAAAAATGGCTTTAGTGATAAGATTAAGGTTATCAACAAGCATTCCACCGAGGTGACTGT AGGTCCAGAGGGTGACATGCCATGCCGTGCCAACATCCTGGTCACAGAGTTGTTTGACACAGAGCTGATCGGGGAGGGGGCGCTGCCCTC CTATGAGCACGCACACAGGCATCTCGTGGAGGAAAATTGTGAGGCCGTGCCCCACAGAGCCACCGTCTATGCACAGCTGGTGGAGTCCGG GAGGATGTGGTCGTGGAACAAGCTATTTCCCATCCACGTGCAGACCAGCCTCGGAGAGCAGGTCATCGTCCCTCCCGTTGACGTGGAGAG CTGCCCTGGCGCACCCTCTGTCTGTGACATTCAGCTGAACCAGGTGTCACCAGCCGACTTTACAGTCCTCAGCGATGTGCTGCCCATGTT CAGCATAGACTTCAGCAAGCAAGTCAGTAGCTCAGCAGCCTGCCATAGCAGGCGGTTTGAACCTCTGACATCTGGCCGAGCTCAGGTGGT TCTCTCGTGGTGGGACATTGAAATGGACCCTGAGGGGAAGATCAAGTGCACCATGGCCCCCTTCTGGGCACACTCAGACCCAGAGGAGAT GCAGTGGCGGGACCACTGGATGCAGTGTGTGTACTTCCTGCCACAAGAGGAGCCTGTGGTGCAGGGCTCAGCGCTCTATCTGGTAGCCCA CCACGATGACTACTGCGTATGGTACAGCCTGCAGAGGACCAGCCCTGAAAAGAATGAGAGAGTCCGCCAGATGCGCCCCGTGTGTGACTG CCAGGCTCACCTGCTCTGGAACCGGCCTCGGTTTGGAGAGATCAATGACCAGGACAGAACTGATCGATACGTCCAGGCTCTGAGGACCAG CACAATCATTGTGGAGAAGACAGTTCAAGACCTCCTGAACCTGATGCATGACTTGAGTGCATATTCAGATCAATTCCTCAACATGGTGTG CGTGAAGCTCCAGGAGTACAAGGACACCTGCACTGCAGCTTACAGGGGTATTGTCCAGTCAGAAGAAAAACTTGTCATCAGTGCATCCTG GGCAAAAGATGATGATATCAGCAGACTCTTGAAATCTCTACCAAACTGGATGAATATGGCTCAACCCAAACAGCTGAGGCCAAAAAGAGA GGAGGAAGAAGATTTCATAAGGGCAGCTTTTGGCAAGGAGTCTGAAGTTCTTATTGGGAACCTGGGTGATAAATTAATCCCTCCACAAGA CATCCTTCGTGACGTCAGTGACCTCAAAGCCTTGGCCAACATGCATGAAAGCCTGGAATGGTTGGCAAGTCGAACAAAGTCAGCTTTCTC CAATCTTTCTACATCCCAGATGCTTTCTCCTGCTCAAGACAGCCACACGAACACGGATCTCCCCCCAGTGTCAGAGCAGATCATGCAGAC TCTCAGTGAACTTGCCAAATCGTTCCAGGATATGGCTGACCGCTGCTTGCTTGTCTTACATCTGGAAGTGAGGGTTCACTGTTTCCACTA TCTTATCCCTCTTGCAAAGGAGGGGAACTATGCCATTGTGGCTAATGTGGAAAGTATGGATTATGACCCCCTGGTGGTCAAGCTCAACAA AGATATCAGCGCCATTGAAGAGGCCATGAGCGCCAGCCTTCAGCAGCACAAGTTCCAGTATATCTTCGAAGGCCTGGGCCACCTGATCTC CTGCATCCTCATTAATGGTGCCCAGTACTTCAGGCGCATCAGTGAGTCTGGCATCAAGAAAATGTGTAGGAACATTTTTGTTCTTCAGCA GAATTTGACCAACATCACCATGTCGCGGGAGGCAGACCTGGACTTTGCAAGGCAGTACTACGAGATGCTTTACAACACAGCTGACGAGCT CCTGAACCTGGTGGTGGACCAGGGTGTGAAGTACACGGAGCTGGAGTACATCCACGCTCTGACCCTGCTGCACCGCAGCCAGACTGGGGT GGGGGAACTGACCACCCAGAACACGAGGCTGCAGAGGCTCAAAGAGATCATCTGCGAGCAGGCTGCCATCAAGCAAGCCACCAAGGACAA >In-frame_ENST00000449359_ENST00000539845_TCGA-DX-A7EF-01A_PRMT7_chr16_68380183_+_EXOC4_chr7_133580352_length(amino acids)=765AA_start in transcript=61_stop in transcript=2358 MSTRTQLARLLFCAKTGELVGTMKIFCSRANPTTGSVEWLEEDEHYDYHQEIARSSYADMLHDKDRVFKPMADAAVKIVEKNGFSDKIKV INKHSTEVTVGPEGDMPCRANILVTELFDTELIGEGALPSYEHAHRHLVEENCEAVPHRATVYAQLVESGRMWSWNKLFPIHVQTSLGEQ VIVPPVDVESCPGAPSVCDIQLNQVSPADFTVLSDVLPMFSIDFSKQVSSSAACHSRRFEPLTSGRAQVVLSWWDIEMDPEGKIKCTMAP FWAHSDPEEMQWRDHWMQCVYFLPQEEPVVQGSALYLVAHHDDYCVWYSLQRTSPEKNERVRQMRPVCDCQAHLLWNRPRFGEINDQDRT DRYVQALRTSTIIVEKTVQDLLNLMHDLSAYSDQFLNMVCVKLQEYKDTCTAAYRGIVQSEEKLVISASWAKDDDISRLLKSLPNWMNMA QPKQLRPKREEEEDFIRAAFGKESEVLIGNLGDKLIPPQDILRDVSDLKALANMHESLEWLASRTKSAFSNLSTSQMLSPAQDSHTNTDL PPVSEQIMQTLSELAKSFQDMADRCLLVLHLEVRVHCFHYLIPLAKEGNYAIVANVESMDYDPLVVKLNKDISAIEEAMSASLQQHKFQY IFEGLGHLISCILINGAQYFRRISESGIKKMCRNIFVLQQNLTNITMSREADLDFARQYYEMLYNTADELLNLVVDQGVKYTELEYIHAL -------------------------------------------------------------- >In-frame_ENST00000441236_ENST00000253861_TCGA-DX-A7EF-01A_PRMT7_chr16_68380183_+_EXOC4_chr7_133580352_length(transcript)=4295nt_BP=1873nt CGCTTTGGGGTTCTGTGTGCAGCGAGCATGGTGTCCTTGGCACCAGGGTTTCGGCAGAGGAGCCTAGCGTGGGCCTACTTGGACTCCTCC GCGTGGGGCAGCTCGGGACACCCGGGCCTGCAGGAGAGCGGGGTTCTAGGCTGGCCCCGGCTCTGCAGTGCAGCCGGGTGCCTGCCACTC GCGGGGCTCTGTCGCAGTACTCGTGCCTGGCGCCTCCCCTCAGCCACAGAGACCGCAGTAGCTCCAACCATCGCACCCCTAACTGGGCCA CGAGTTCTCTGATTGCCAGACCTGTTGTCTTTGCCACTCACTGTTCTGAGTAATTGGAGAGTCGTGTATTCACTACACGCCAACCAGAGT GGTCCTGTAAAAGCGTAAGCCTAGTGTAGATACGCTTCTGCTTAAAACTCTTGAGTGGCTCCCAGTGCTTTTAGAACAAAATCCAAACGC CTTTCCGAAGTCGACAAGGCCCAGCTTGATTGAGCAGAAGATGTGATAGGAGATGAGGAGCGGGGGGCTTCTGCAAAAGTGCTTCGGTCG CTCAGGCTTTTGGCACATTTTGCTTATGCAACCTAGTTCTTTCTACCTTAGGGCCTTTTCTTGGGAAAGTTGGGAGTCTCACTCTGCTGC CTAGGCTGAGTGCAGTGGTGTGATCGAGGCGCACTGCAGCCTTGACCTCCTGGGCTCAAGCGATCCTCACCTCGGCCTACCGAGTAGCTG GGACTACAGGCACGCGCCACTACACTCGGATTTCTGACAGTCAGACTTGTCCACAAGAACTCAACTGGCAAGGCTGCTTTTCTGTGCTAA AACTGGGGAGCTAGTGGGCACCATGAAGATCTTCTGCAGTCGGGCCAATCCGACCACGGGGTCTGTGGAGTGGCTGGAGGAGGATGAACA CTATGATTACCACCAGGAGATTGCAAGGTCATCTTATGCAGATATGCTACATGACAAAGACAGAGTTTTCAAGCCTATGGCTGATGCTGC TGTGAAGATTGTGGAGAAAAATGGCTTTAGTGATAAGATTAAGGTTATCAACAAGCATTCCACCGAGGTGACTGTAGGTCCAGAGGGTGA CATGCCATGCCGTGCCAACATCCTGGTCACAGAGTTGTTTGACACAGAGCTGATCGGGGAGGGGGCGCTGCCCTCCTATGAGCACGCACA CAGGCATCTCGTGGAGGAAAATTGTGAGGCCGTGCCCCACAGAGCCACCGTCTATGCACAGCTGGTGGAGTCCGGGAGGATGTGGTCGTG GAACAAGCTATTTCCCATCCACGTGCAGACCAGCCTCGGAGAGCAGGTCATCGTCCCTCCCGTTGACGTGGAGAGCTGCCCTGGCGCACC CTCTGTCTGTGACATTCAGCTGAACCAGGTGTCACCAGCCGACTTTACAGTCCTCAGCGATGTGCTGCCCATGTTCAGCATAGACTTCAG CAAGCAAGTCAGTAGCTCAGCAGCCTGCCATAGCAGGCGGTTTGAACCTCTGACATCTGGCCGAGCTCAGGTGGTTCTCTCGTGGTGGGA CATTGAAATGGACCCTGAGGGGAAGATCAAGTGCACCATGGCCCCCTTCTGGGCACACTCAGACCCAGAGGAGATGCAGTGGCGGGACCA CTGGATGCAGTGTGTGTACTTCCTGCCACAAGAGGAGCCTGTGGTGCAGGGCTCAGCGCTCTATCTGGTAGCCCACCACGATGACTACTG CGTATGGTACAGCCTGCAGAGGACCAGCCCTGAAAAGAATGAGAGAGTCCGCCAGATGCGCCCCGTGTGTGACTGCCAGGCTCACCTGCT CTGGAACCGGCCTCGGTTTGGAGAGATCAATGACCAGGACAGAACTGATCGATACGTCCAGGCTCTGAGGACCAGCACAATCATTGTGGA GAAGACAGTTCAAGACCTCCTGAACCTGATGCATGACTTGAGTGCATATTCAGATCAATTCCTCAACATGGTGTGCGTGAAGCTCCAGGA GTACAAGGACACCTGCACTGCAGCTTACAGGGGTATTGTCCAGTCAGAAGAAAAACTTGTCATCAGTGCATCCTGGGCAAAAGATGATGA TATCAGCAGACTCTTGAAATCTCTACCAAACTGGATGAATATGGCTCAACCCAAACAGCTGAGGCCAAAAAGAGAGGAGGAAGAAGATTT CATAAGGGCAGCTTTTGGCAAGGAGTCTGAAGTTCTTATTGGGAACCTGGGTGATAAATTAATCCCTCCACAAGACATCCTTCGTGACGT CAGTGACCTCAAAGCCTTGGCCAACATGCATGAAAGCCTGGAATGGTTGGCAAGTCGAACAAAGTCAGCTTTCTCCAATCTTTCTACATC CCAGATGCTTTCTCCTGCTCAAGACAGCCACACGAACACGGATCTCCCCCCAGTGTCAGAGCAGATCATGCAGACTCTCAGTGAACTTGC CAAATCGTTCCAGGATATGGCTGACCGCTGCTTGCTTGTCTTACATCTGGAAGTGAGGGTTCACTGTTTCCACTATCTTATCCCTCTTGC AAAGGAGGGGAACTATGCCATTGTGGCTAATGTGGAAAGTATGGATTATGACCCCCTGGTGGTCAAGCTCAACAAAGATATCAGCGCCAT TGAAGAGGCCATGAGCGCCAGCCTTCAGCAGCACAAGTTCCAGTATATCTTCGAAGGCCTGGGCCACCTGATCTCCTGCATCCTCATTAA TGGTGCCCAGTACTTCAGGCGCATCAGTGAGTCTGGCATCAAGAAAATGTGTAGGAACATTTTTGTTCTTCAGCAGAATTTGACCAACAT CACCATGTCGCGGGAGGCAGACCTGGACTTTGCAAGGCAGTACTACGAGATGCTTTACAACACAGCTGACGAGCTCCTGAACCTGGTGGT GGACCAGGGTGTGAAGTACACGGAGCTGGAGTACATCCACGCTCTGACCCTGCTGCACCGCAGCCAGACTGGGGTGGGGGAACTGACCAC CCAGAACACGAGGCTGCAGAGGCTCAAAGAGATCATCTGCGAGCAGGCTGCCATCAAGCAAGCCACCAAGGACAAGAAGATAACTACCGT TTAGCAGGGCGTACTGCGGTTGGTGACGGGGGTCCCCTCAGTCACACTCACTTTTTTCCTTGGTATGTTATTGAGTATATTCTGAGCTTA GTTTTCTCTACAGTGATACTTTAGTGGAGAGGAGGTGTAAGGATTCTTTCTCTCTGGTTTTGGCTTTTCATATAAATGCTAAAGGAAGGC GACAGTACAGAGTGTTTTGGTTGAACAACTACTTTAATGCAGTCAAATCTAACGGGACTAGGGTGGGATAGGGAGGAAGGTGGTATCAAA TTGTTGGACTCTGAAAAACAAGTGGATGGATTACTAATATTTGATTTATTACTCAATATATATATAATTCCAGCCTTGGAAAGTAGGAAA GTAGGCTGCTACCTAACTTTTAGTCCCTTCCAAAACCATTTAGTAGGGTTCTATTACATAAACAGTAGGGTTTTTCCTCTCCTGACCTTA TCCGTTTACAGTTCAATGAAATAAGTGTATGTGCATTGCTGTCTGTCTCTATTGCCAAAATCAAATAAATGGCTTCTCAGCTGCTGTTTA CAACAAACTTCCCTAACCAAAACAGAACCTCTAATTTAGGGCTAGGAATAGAAGTCTTTTGATCCCAGTCCCTGGGACAGTTTTGTATGC TGTATCTTGTACACAGGTTGTAGGTTGGTTTATTGCCATTTTGTTTTATTTCTGCTGTATAAAAACCAAGAGCCAGACAATTAGACAACT ATGGAGGAATGAAAGGCAATTCAAACATCTGCTTGATTCCCGCCCCGCCACCCCTAATTTCTGAGAGAATAATGGTTAGAGAACATTGCA TCTCACTTGAAACATCCTTTGGGGGTAAATGATTCTTAGGTGCTCACTTGGTCTGAGCTCAGCTGAATGCAGGGAAGATGGGACAGAGTG ACATTTCTCCTCTGTGCGGCCTCCAGCTGAGCCTGTCTCTGAATTGTTCCCTCCCCCGCAATGTGGGCACTTACCATGTTCCTGGCACAC TGGACCTCACCATGTCCCCCGGTCACCAGTCCTCTTGCTGCCCATGGTTCATAGGTCATAGAAGGCAGCAATGCACTGACTGGGCCACAT CTTGAAAACTCGTGGAAAGGGAAAGGGGAGGAGATGGGACTTTGACCACACACAGTGATGCCTCACACCCTGAAGGTGGGGGATTTTGTA >In-frame_ENST00000441236_ENST00000253861_TCGA-DX-A7EF-01A_PRMT7_chr16_68380183_+_EXOC4_chr7_133580352_length(amino acids)=765AA_start in transcript=766_stop in transcript=3063 MSTRTQLARLLFCAKTGELVGTMKIFCSRANPTTGSVEWLEEDEHYDYHQEIARSSYADMLHDKDRVFKPMADAAVKIVEKNGFSDKIKV INKHSTEVTVGPEGDMPCRANILVTELFDTELIGEGALPSYEHAHRHLVEENCEAVPHRATVYAQLVESGRMWSWNKLFPIHVQTSLGEQ VIVPPVDVESCPGAPSVCDIQLNQVSPADFTVLSDVLPMFSIDFSKQVSSSAACHSRRFEPLTSGRAQVVLSWWDIEMDPEGKIKCTMAP FWAHSDPEEMQWRDHWMQCVYFLPQEEPVVQGSALYLVAHHDDYCVWYSLQRTSPEKNERVRQMRPVCDCQAHLLWNRPRFGEINDQDRT DRYVQALRTSTIIVEKTVQDLLNLMHDLSAYSDQFLNMVCVKLQEYKDTCTAAYRGIVQSEEKLVISASWAKDDDISRLLKSLPNWMNMA QPKQLRPKREEEEDFIRAAFGKESEVLIGNLGDKLIPPQDILRDVSDLKALANMHESLEWLASRTKSAFSNLSTSQMLSPAQDSHTNTDL PPVSEQIMQTLSELAKSFQDMADRCLLVLHLEVRVHCFHYLIPLAKEGNYAIVANVESMDYDPLVVKLNKDISAIEEAMSASLQQHKFQY IFEGLGHLISCILINGAQYFRRISESGIKKMCRNIFVLQQNLTNITMSREADLDFARQYYEMLYNTADELLNLVVDQGVKYTELEYIHAL -------------------------------------------------------------- >In-frame_ENST00000441236_ENST00000539845_TCGA-DX-A7EF-01A_PRMT7_chr16_68380183_+_EXOC4_chr7_133580352_length(transcript)=3123nt_BP=1873nt CGCTTTGGGGTTCTGTGTGCAGCGAGCATGGTGTCCTTGGCACCAGGGTTTCGGCAGAGGAGCCTAGCGTGGGCCTACTTGGACTCCTCC GCGTGGGGCAGCTCGGGACACCCGGGCCTGCAGGAGAGCGGGGTTCTAGGCTGGCCCCGGCTCTGCAGTGCAGCCGGGTGCCTGCCACTC GCGGGGCTCTGTCGCAGTACTCGTGCCTGGCGCCTCCCCTCAGCCACAGAGACCGCAGTAGCTCCAACCATCGCACCCCTAACTGGGCCA CGAGTTCTCTGATTGCCAGACCTGTTGTCTTTGCCACTCACTGTTCTGAGTAATTGGAGAGTCGTGTATTCACTACACGCCAACCAGAGT GGTCCTGTAAAAGCGTAAGCCTAGTGTAGATACGCTTCTGCTTAAAACTCTTGAGTGGCTCCCAGTGCTTTTAGAACAAAATCCAAACGC CTTTCCGAAGTCGACAAGGCCCAGCTTGATTGAGCAGAAGATGTGATAGGAGATGAGGAGCGGGGGGCTTCTGCAAAAGTGCTTCGGTCG CTCAGGCTTTTGGCACATTTTGCTTATGCAACCTAGTTCTTTCTACCTTAGGGCCTTTTCTTGGGAAAGTTGGGAGTCTCACTCTGCTGC CTAGGCTGAGTGCAGTGGTGTGATCGAGGCGCACTGCAGCCTTGACCTCCTGGGCTCAAGCGATCCTCACCTCGGCCTACCGAGTAGCTG GGACTACAGGCACGCGCCACTACACTCGGATTTCTGACAGTCAGACTTGTCCACAAGAACTCAACTGGCAAGGCTGCTTTTCTGTGCTAA AACTGGGGAGCTAGTGGGCACCATGAAGATCTTCTGCAGTCGGGCCAATCCGACCACGGGGTCTGTGGAGTGGCTGGAGGAGGATGAACA CTATGATTACCACCAGGAGATTGCAAGGTCATCTTATGCAGATATGCTACATGACAAAGACAGAGTTTTCAAGCCTATGGCTGATGCTGC TGTGAAGATTGTGGAGAAAAATGGCTTTAGTGATAAGATTAAGGTTATCAACAAGCATTCCACCGAGGTGACTGTAGGTCCAGAGGGTGA CATGCCATGCCGTGCCAACATCCTGGTCACAGAGTTGTTTGACACAGAGCTGATCGGGGAGGGGGCGCTGCCCTCCTATGAGCACGCACA CAGGCATCTCGTGGAGGAAAATTGTGAGGCCGTGCCCCACAGAGCCACCGTCTATGCACAGCTGGTGGAGTCCGGGAGGATGTGGTCGTG GAACAAGCTATTTCCCATCCACGTGCAGACCAGCCTCGGAGAGCAGGTCATCGTCCCTCCCGTTGACGTGGAGAGCTGCCCTGGCGCACC CTCTGTCTGTGACATTCAGCTGAACCAGGTGTCACCAGCCGACTTTACAGTCCTCAGCGATGTGCTGCCCATGTTCAGCATAGACTTCAG CAAGCAAGTCAGTAGCTCAGCAGCCTGCCATAGCAGGCGGTTTGAACCTCTGACATCTGGCCGAGCTCAGGTGGTTCTCTCGTGGTGGGA CATTGAAATGGACCCTGAGGGGAAGATCAAGTGCACCATGGCCCCCTTCTGGGCACACTCAGACCCAGAGGAGATGCAGTGGCGGGACCA CTGGATGCAGTGTGTGTACTTCCTGCCACAAGAGGAGCCTGTGGTGCAGGGCTCAGCGCTCTATCTGGTAGCCCACCACGATGACTACTG CGTATGGTACAGCCTGCAGAGGACCAGCCCTGAAAAGAATGAGAGAGTCCGCCAGATGCGCCCCGTGTGTGACTGCCAGGCTCACCTGCT CTGGAACCGGCCTCGGTTTGGAGAGATCAATGACCAGGACAGAACTGATCGATACGTCCAGGCTCTGAGGACCAGCACAATCATTGTGGA GAAGACAGTTCAAGACCTCCTGAACCTGATGCATGACTTGAGTGCATATTCAGATCAATTCCTCAACATGGTGTGCGTGAAGCTCCAGGA GTACAAGGACACCTGCACTGCAGCTTACAGGGGTATTGTCCAGTCAGAAGAAAAACTTGTCATCAGTGCATCCTGGGCAAAAGATGATGA TATCAGCAGACTCTTGAAATCTCTACCAAACTGGATGAATATGGCTCAACCCAAACAGCTGAGGCCAAAAAGAGAGGAGGAAGAAGATTT CATAAGGGCAGCTTTTGGCAAGGAGTCTGAAGTTCTTATTGGGAACCTGGGTGATAAATTAATCCCTCCACAAGACATCCTTCGTGACGT CAGTGACCTCAAAGCCTTGGCCAACATGCATGAAAGCCTGGAATGGTTGGCAAGTCGAACAAAGTCAGCTTTCTCCAATCTTTCTACATC CCAGATGCTTTCTCCTGCTCAAGACAGCCACACGAACACGGATCTCCCCCCAGTGTCAGAGCAGATCATGCAGACTCTCAGTGAACTTGC CAAATCGTTCCAGGATATGGCTGACCGCTGCTTGCTTGTCTTACATCTGGAAGTGAGGGTTCACTGTTTCCACTATCTTATCCCTCTTGC AAAGGAGGGGAACTATGCCATTGTGGCTAATGTGGAAAGTATGGATTATGACCCCCTGGTGGTCAAGCTCAACAAAGATATCAGCGCCAT TGAAGAGGCCATGAGCGCCAGCCTTCAGCAGCACAAGTTCCAGTATATCTTCGAAGGCCTGGGCCACCTGATCTCCTGCATCCTCATTAA TGGTGCCCAGTACTTCAGGCGCATCAGTGAGTCTGGCATCAAGAAAATGTGTAGGAACATTTTTGTTCTTCAGCAGAATTTGACCAACAT CACCATGTCGCGGGAGGCAGACCTGGACTTTGCAAGGCAGTACTACGAGATGCTTTACAACACAGCTGACGAGCTCCTGAACCTGGTGGT GGACCAGGGTGTGAAGTACACGGAGCTGGAGTACATCCACGCTCTGACCCTGCTGCACCGCAGCCAGACTGGGGTGGGGGAACTGACCAC CCAGAACACGAGGCTGCAGAGGCTCAAAGAGATCATCTGCGAGCAGGCTGCCATCAAGCAAGCCACCAAGGACAAGAAGATAACTACCGT >In-frame_ENST00000441236_ENST00000539845_TCGA-DX-A7EF-01A_PRMT7_chr16_68380183_+_EXOC4_chr7_133580352_length(amino acids)=765AA_start in transcript=766_stop in transcript=3063 MSTRTQLARLLFCAKTGELVGTMKIFCSRANPTTGSVEWLEEDEHYDYHQEIARSSYADMLHDKDRVFKPMADAAVKIVEKNGFSDKIKV INKHSTEVTVGPEGDMPCRANILVTELFDTELIGEGALPSYEHAHRHLVEENCEAVPHRATVYAQLVESGRMWSWNKLFPIHVQTSLGEQ VIVPPVDVESCPGAPSVCDIQLNQVSPADFTVLSDVLPMFSIDFSKQVSSSAACHSRRFEPLTSGRAQVVLSWWDIEMDPEGKIKCTMAP FWAHSDPEEMQWRDHWMQCVYFLPQEEPVVQGSALYLVAHHDDYCVWYSLQRTSPEKNERVRQMRPVCDCQAHLLWNRPRFGEINDQDRT DRYVQALRTSTIIVEKTVQDLLNLMHDLSAYSDQFLNMVCVKLQEYKDTCTAAYRGIVQSEEKLVISASWAKDDDISRLLKSLPNWMNMA QPKQLRPKREEEEDFIRAAFGKESEVLIGNLGDKLIPPQDILRDVSDLKALANMHESLEWLASRTKSAFSNLSTSQMLSPAQDSHTNTDL PPVSEQIMQTLSELAKSFQDMADRCLLVLHLEVRVHCFHYLIPLAKEGNYAIVANVESMDYDPLVVKLNKDISAIEEAMSASLQQHKFQY IFEGLGHLISCILINGAQYFRRISESGIKKMCRNIFVLQQNLTNITMSREADLDFARQYYEMLYNTADELLNLVVDQGVKYTELEYIHAL -------------------------------------------------------------- >In-frame_ENST00000348497_ENST00000253861_TCGA-DX-A7EF-01A_PRMT7_chr16_68380183_+_EXOC4_chr7_133580352_length(transcript)=4223nt_BP=1801nt CGCTTTGGGGTTCTGTGTGCAGCGAGCATGGTGTCCTTGGCACCAGGGTTTCGGCAGAGGAGCCTAGCGTGGGCCTACTTGGACTCCTCC GCGTGGGGCAGCTCGGGACACCCGGGCCTGCAGGAGAGCGGGGTTCTAGGCTGGCCCCGGCTCTGCAGTGCAGCCGGGTGCCTGCCACTC GCGGGGCTCTGTCGCAGTACTCGTGCCTGGCGCCTCCCCTCAGCCACAGAGACCGCAGTAGCTCCAACCATCGCACCCCTAACTGGGCCA CGAGTTCTCTGATTGCCAGACCTGTTGTCTTTGCCACTCACTGTTCTGAGTAATTGGAGAGTCGTGTATTCACTACACGCCAACCAGAGT GGTCCTGTAAAAGCGTAAGCCTAGTGTAGATACGCTTCTGCTTAAAACTCTTGAGTGGCTCCCAGTGCTTTTAGAACAAAATCCAAACGC CTTTCCGAAGTCGACAAGGCCCAGCTTGATTGAGCAGAAGATGTGATAGGAGATGAGGAGCGGGGGGCTTCTGCAAAAGTGCTTCGGTCG CTCAGGCTTTTGGCACATTTTGCTTATGCAACCTAGTTCTTTCTACCTTAGGGCCTTTTCTTGGGAAAGTTGGGAGTCTCACTCTGCTGC CTAGGCTGAGTGCAGTGGTGTGATCGAGGCGCACTGCAGCCTTGACCTCCTGGGCTCAAGCGATCCTCACCTCGGCCTACCGAGTAGCTG GGACTACAGGCACGCGCCACTACACTCGGATTTCTGACAGTCAGACTTGTCCACAAGAACTCAACTGGCAAGGCTGCTTTTCTGTGCTAA AACTGGGGAGCTAGTGGGCACCATGAAGATCTTCTGCAGTCGGGCCAATCCGACCACGGGGTCTGTGGAGTGGCTGGAGGAGGATGAACA CTATGATTACCACCAGGAGATTGCAAGGTCATCTTATGCAGATATGCTACATGACAAAGACAGAAATGTAAAATACTACCAAGGTATCCG GGCTGCCGTGAGCAGGGTGAAGGACAGAGGACAGAAGGCCTTGGTTCTCGACATTGGCACTGGCACGGGACTCTTGTCAATGATGGCGGT CACAGCAGGTGCCGACTTCTGCTATGCCATCGAGGAAAATTGTGAGGCCGTGCCCCACAGAGCCACCGTCTATGCACAGCTGGTGGAGTC CGGGAGGATGTGGTCGTGGAACAAGCTATTTCCCATCCACGTGCAGACCAGCCTCGGAGAGCAGGTCATCGTCCCTCCCGTTGACGTGGA GAGCTGCCCTGGCGCACCCTCTGTCTGTGACATTCAGCTGAACCAGGTGTCACCAGCCGACTTTACAGTCCTCAGCGATGTGCTGCCCAT GTTCAGCATAGACTTCAGCAAGCAAGTCAGTAGCTCAGCAGCCTGCCATAGCAGGCGGTTTGAACCTCTGACATCTGGCCGAGCTCAGGT GGTTCTCTCGTGGTGGGACATTGAAATGGACCCTGAGGGGAAGATCAAGTGCACCATGGCCCCCTTCTGGGCACACTCAGACCCAGAGGA GATGCAGTGGCGGGACCACTGGATGCAGTGTGTGTACTTCCTGCCACAAGAGGAGCCTGTGGTGCAGGGCTCAGCGCTCTATCTGGTAGC CCACCACGATGACTACTGCGTATGGTACAGCCTGCAGAGGACCAGCCCTGAAAAGAATGAGAGAGTCCGCCAGATGCGCCCCGTGTGTGA CTGCCAGGCTCACCTGCTCTGGAACCGGCCTCGGTTTGGAGAGATCAATGACCAGGACAGAACTGATCGATACGTCCAGGCTCTGAGGAC CAGCACAATCATTGTGGAGAAGACAGTTCAAGACCTCCTGAACCTGATGCATGACTTGAGTGCATATTCAGATCAATTCCTCAACATGGT GTGCGTGAAGCTCCAGGAGTACAAGGACACCTGCACTGCAGCTTACAGGGGTATTGTCCAGTCAGAAGAAAAACTTGTCATCAGTGCATC CTGGGCAAAAGATGATGATATCAGCAGACTCTTGAAATCTCTACCAAACTGGATGAATATGGCTCAACCCAAACAGCTGAGGCCAAAAAG AGAGGAGGAAGAAGATTTCATAAGGGCAGCTTTTGGCAAGGAGTCTGAAGTTCTTATTGGGAACCTGGGTGATAAATTAATCCCTCCACA AGACATCCTTCGTGACGTCAGTGACCTCAAAGCCTTGGCCAACATGCATGAAAGCCTGGAATGGTTGGCAAGTCGAACAAAGTCAGCTTT CTCCAATCTTTCTACATCCCAGATGCTTTCTCCTGCTCAAGACAGCCACACGAACACGGATCTCCCCCCAGTGTCAGAGCAGATCATGCA GACTCTCAGTGAACTTGCCAAATCGTTCCAGGATATGGCTGACCGCTGCTTGCTTGTCTTACATCTGGAAGTGAGGGTTCACTGTTTCCA CTATCTTATCCCTCTTGCAAAGGAGGGGAACTATGCCATTGTGGCTAATGTGGAAAGTATGGATTATGACCCCCTGGTGGTCAAGCTCAA CAAAGATATCAGCGCCATTGAAGAGGCCATGAGCGCCAGCCTTCAGCAGCACAAGTTCCAGTATATCTTCGAAGGCCTGGGCCACCTGAT CTCCTGCATCCTCATTAATGGTGCCCAGTACTTCAGGCGCATCAGTGAGTCTGGCATCAAGAAAATGTGTAGGAACATTTTTGTTCTTCA GCAGAATTTGACCAACATCACCATGTCGCGGGAGGCAGACCTGGACTTTGCAAGGCAGTACTACGAGATGCTTTACAACACAGCTGACGA GCTCCTGAACCTGGTGGTGGACCAGGGTGTGAAGTACACGGAGCTGGAGTACATCCACGCTCTGACCCTGCTGCACCGCAGCCAGACTGG GGTGGGGGAACTGACCACCCAGAACACGAGGCTGCAGAGGCTCAAAGAGATCATCTGCGAGCAGGCTGCCATCAAGCAAGCCACCAAGGA CAAGAAGATAACTACCGTTTAGCAGGGCGTACTGCGGTTGGTGACGGGGGTCCCCTCAGTCACACTCACTTTTTTCCTTGGTATGTTATT GAGTATATTCTGAGCTTAGTTTTCTCTACAGTGATACTTTAGTGGAGAGGAGGTGTAAGGATTCTTTCTCTCTGGTTTTGGCTTTTCATA TAAATGCTAAAGGAAGGCGACAGTACAGAGTGTTTTGGTTGAACAACTACTTTAATGCAGTCAAATCTAACGGGACTAGGGTGGGATAGG GAGGAAGGTGGTATCAAATTGTTGGACTCTGAAAAACAAGTGGATGGATTACTAATATTTGATTTATTACTCAATATATATATAATTCCA GCCTTGGAAAGTAGGAAAGTAGGCTGCTACCTAACTTTTAGTCCCTTCCAAAACCATTTAGTAGGGTTCTATTACATAAACAGTAGGGTT TTTCCTCTCCTGACCTTATCCGTTTACAGTTCAATGAAATAAGTGTATGTGCATTGCTGTCTGTCTCTATTGCCAAAATCAAATAAATGG CTTCTCAGCTGCTGTTTACAACAAACTTCCCTAACCAAAACAGAACCTCTAATTTAGGGCTAGGAATAGAAGTCTTTTGATCCCAGTCCC TGGGACAGTTTTGTATGCTGTATCTTGTACACAGGTTGTAGGTTGGTTTATTGCCATTTTGTTTTATTTCTGCTGTATAAAAACCAAGAG CCAGACAATTAGACAACTATGGAGGAATGAAAGGCAATTCAAACATCTGCTTGATTCCCGCCCCGCCACCCCTAATTTCTGAGAGAATAA TGGTTAGAGAACATTGCATCTCACTTGAAACATCCTTTGGGGGTAAATGATTCTTAGGTGCTCACTTGGTCTGAGCTCAGCTGAATGCAG GGAAGATGGGACAGAGTGACATTTCTCCTCTGTGCGGCCTCCAGCTGAGCCTGTCTCTGAATTGTTCCCTCCCCCGCAATGTGGGCACTT ACCATGTTCCTGGCACACTGGACCTCACCATGTCCCCCGGTCACCAGTCCTCTTGCTGCCCATGGTTCATAGGTCATAGAAGGCAGCAAT GCACTGACTGGGCCACATCTTGAAAACTCGTGGAAAGGGAAAGGGGAGGAGATGGGACTTTGACCACACACAGTGATGCCTCACACCCTG >In-frame_ENST00000348497_ENST00000253861_TCGA-DX-A7EF-01A_PRMT7_chr16_68380183_+_EXOC4_chr7_133580352_length(amino acids)=741AA_start in transcript=766_stop in transcript=2991 MSTRTQLARLLFCAKTGELVGTMKIFCSRANPTTGSVEWLEEDEHYDYHQEIARSSYADMLHDKDRNVKYYQGIRAAVSRVKDRGQKALV LDIGTGTGLLSMMAVTAGADFCYAIEENCEAVPHRATVYAQLVESGRMWSWNKLFPIHVQTSLGEQVIVPPVDVESCPGAPSVCDIQLNQ VSPADFTVLSDVLPMFSIDFSKQVSSSAACHSRRFEPLTSGRAQVVLSWWDIEMDPEGKIKCTMAPFWAHSDPEEMQWRDHWMQCVYFLP QEEPVVQGSALYLVAHHDDYCVWYSLQRTSPEKNERVRQMRPVCDCQAHLLWNRPRFGEINDQDRTDRYVQALRTSTIIVEKTVQDLLNL MHDLSAYSDQFLNMVCVKLQEYKDTCTAAYRGIVQSEEKLVISASWAKDDDISRLLKSLPNWMNMAQPKQLRPKREEEEDFIRAAFGKES EVLIGNLGDKLIPPQDILRDVSDLKALANMHESLEWLASRTKSAFSNLSTSQMLSPAQDSHTNTDLPPVSEQIMQTLSELAKSFQDMADR CLLVLHLEVRVHCFHYLIPLAKEGNYAIVANVESMDYDPLVVKLNKDISAIEEAMSASLQQHKFQYIFEGLGHLISCILINGAQYFRRIS ESGIKKMCRNIFVLQQNLTNITMSREADLDFARQYYEMLYNTADELLNLVVDQGVKYTELEYIHALTLLHRSQTGVGELTTQNTRLQRLK -------------------------------------------------------------- >In-frame_ENST00000348497_ENST00000539845_TCGA-DX-A7EF-01A_PRMT7_chr16_68380183_+_EXOC4_chr7_133580352_length(transcript)=3051nt_BP=1801nt CGCTTTGGGGTTCTGTGTGCAGCGAGCATGGTGTCCTTGGCACCAGGGTTTCGGCAGAGGAGCCTAGCGTGGGCCTACTTGGACTCCTCC GCGTGGGGCAGCTCGGGACACCCGGGCCTGCAGGAGAGCGGGGTTCTAGGCTGGCCCCGGCTCTGCAGTGCAGCCGGGTGCCTGCCACTC GCGGGGCTCTGTCGCAGTACTCGTGCCTGGCGCCTCCCCTCAGCCACAGAGACCGCAGTAGCTCCAACCATCGCACCCCTAACTGGGCCA CGAGTTCTCTGATTGCCAGACCTGTTGTCTTTGCCACTCACTGTTCTGAGTAATTGGAGAGTCGTGTATTCACTACACGCCAACCAGAGT GGTCCTGTAAAAGCGTAAGCCTAGTGTAGATACGCTTCTGCTTAAAACTCTTGAGTGGCTCCCAGTGCTTTTAGAACAAAATCCAAACGC CTTTCCGAAGTCGACAAGGCCCAGCTTGATTGAGCAGAAGATGTGATAGGAGATGAGGAGCGGGGGGCTTCTGCAAAAGTGCTTCGGTCG CTCAGGCTTTTGGCACATTTTGCTTATGCAACCTAGTTCTTTCTACCTTAGGGCCTTTTCTTGGGAAAGTTGGGAGTCTCACTCTGCTGC CTAGGCTGAGTGCAGTGGTGTGATCGAGGCGCACTGCAGCCTTGACCTCCTGGGCTCAAGCGATCCTCACCTCGGCCTACCGAGTAGCTG GGACTACAGGCACGCGCCACTACACTCGGATTTCTGACAGTCAGACTTGTCCACAAGAACTCAACTGGCAAGGCTGCTTTTCTGTGCTAA AACTGGGGAGCTAGTGGGCACCATGAAGATCTTCTGCAGTCGGGCCAATCCGACCACGGGGTCTGTGGAGTGGCTGGAGGAGGATGAACA CTATGATTACCACCAGGAGATTGCAAGGTCATCTTATGCAGATATGCTACATGACAAAGACAGAAATGTAAAATACTACCAAGGTATCCG GGCTGCCGTGAGCAGGGTGAAGGACAGAGGACAGAAGGCCTTGGTTCTCGACATTGGCACTGGCACGGGACTCTTGTCAATGATGGCGGT CACAGCAGGTGCCGACTTCTGCTATGCCATCGAGGAAAATTGTGAGGCCGTGCCCCACAGAGCCACCGTCTATGCACAGCTGGTGGAGTC CGGGAGGATGTGGTCGTGGAACAAGCTATTTCCCATCCACGTGCAGACCAGCCTCGGAGAGCAGGTCATCGTCCCTCCCGTTGACGTGGA GAGCTGCCCTGGCGCACCCTCTGTCTGTGACATTCAGCTGAACCAGGTGTCACCAGCCGACTTTACAGTCCTCAGCGATGTGCTGCCCAT GTTCAGCATAGACTTCAGCAAGCAAGTCAGTAGCTCAGCAGCCTGCCATAGCAGGCGGTTTGAACCTCTGACATCTGGCCGAGCTCAGGT GGTTCTCTCGTGGTGGGACATTGAAATGGACCCTGAGGGGAAGATCAAGTGCACCATGGCCCCCTTCTGGGCACACTCAGACCCAGAGGA GATGCAGTGGCGGGACCACTGGATGCAGTGTGTGTACTTCCTGCCACAAGAGGAGCCTGTGGTGCAGGGCTCAGCGCTCTATCTGGTAGC CCACCACGATGACTACTGCGTATGGTACAGCCTGCAGAGGACCAGCCCTGAAAAGAATGAGAGAGTCCGCCAGATGCGCCCCGTGTGTGA CTGCCAGGCTCACCTGCTCTGGAACCGGCCTCGGTTTGGAGAGATCAATGACCAGGACAGAACTGATCGATACGTCCAGGCTCTGAGGAC CAGCACAATCATTGTGGAGAAGACAGTTCAAGACCTCCTGAACCTGATGCATGACTTGAGTGCATATTCAGATCAATTCCTCAACATGGT GTGCGTGAAGCTCCAGGAGTACAAGGACACCTGCACTGCAGCTTACAGGGGTATTGTCCAGTCAGAAGAAAAACTTGTCATCAGTGCATC CTGGGCAAAAGATGATGATATCAGCAGACTCTTGAAATCTCTACCAAACTGGATGAATATGGCTCAACCCAAACAGCTGAGGCCAAAAAG AGAGGAGGAAGAAGATTTCATAAGGGCAGCTTTTGGCAAGGAGTCTGAAGTTCTTATTGGGAACCTGGGTGATAAATTAATCCCTCCACA AGACATCCTTCGTGACGTCAGTGACCTCAAAGCCTTGGCCAACATGCATGAAAGCCTGGAATGGTTGGCAAGTCGAACAAAGTCAGCTTT CTCCAATCTTTCTACATCCCAGATGCTTTCTCCTGCTCAAGACAGCCACACGAACACGGATCTCCCCCCAGTGTCAGAGCAGATCATGCA GACTCTCAGTGAACTTGCCAAATCGTTCCAGGATATGGCTGACCGCTGCTTGCTTGTCTTACATCTGGAAGTGAGGGTTCACTGTTTCCA CTATCTTATCCCTCTTGCAAAGGAGGGGAACTATGCCATTGTGGCTAATGTGGAAAGTATGGATTATGACCCCCTGGTGGTCAAGCTCAA CAAAGATATCAGCGCCATTGAAGAGGCCATGAGCGCCAGCCTTCAGCAGCACAAGTTCCAGTATATCTTCGAAGGCCTGGGCCACCTGAT CTCCTGCATCCTCATTAATGGTGCCCAGTACTTCAGGCGCATCAGTGAGTCTGGCATCAAGAAAATGTGTAGGAACATTTTTGTTCTTCA GCAGAATTTGACCAACATCACCATGTCGCGGGAGGCAGACCTGGACTTTGCAAGGCAGTACTACGAGATGCTTTACAACACAGCTGACGA GCTCCTGAACCTGGTGGTGGACCAGGGTGTGAAGTACACGGAGCTGGAGTACATCCACGCTCTGACCCTGCTGCACCGCAGCCAGACTGG GGTGGGGGAACTGACCACCCAGAACACGAGGCTGCAGAGGCTCAAAGAGATCATCTGCGAGCAGGCTGCCATCAAGCAAGCCACCAAGGA >In-frame_ENST00000348497_ENST00000539845_TCGA-DX-A7EF-01A_PRMT7_chr16_68380183_+_EXOC4_chr7_133580352_length(amino acids)=741AA_start in transcript=766_stop in transcript=2991 MSTRTQLARLLFCAKTGELVGTMKIFCSRANPTTGSVEWLEEDEHYDYHQEIARSSYADMLHDKDRNVKYYQGIRAAVSRVKDRGQKALV LDIGTGTGLLSMMAVTAGADFCYAIEENCEAVPHRATVYAQLVESGRMWSWNKLFPIHVQTSLGEQVIVPPVDVESCPGAPSVCDIQLNQ VSPADFTVLSDVLPMFSIDFSKQVSSSAACHSRRFEPLTSGRAQVVLSWWDIEMDPEGKIKCTMAPFWAHSDPEEMQWRDHWMQCVYFLP QEEPVVQGSALYLVAHHDDYCVWYSLQRTSPEKNERVRQMRPVCDCQAHLLWNRPRFGEINDQDRTDRYVQALRTSTIIVEKTVQDLLNL MHDLSAYSDQFLNMVCVKLQEYKDTCTAAYRGIVQSEEKLVISASWAKDDDISRLLKSLPNWMNMAQPKQLRPKREEEEDFIRAAFGKES EVLIGNLGDKLIPPQDILRDVSDLKALANMHESLEWLASRTKSAFSNLSTSQMLSPAQDSHTNTDLPPVSEQIMQTLSELAKSFQDMADR CLLVLHLEVRVHCFHYLIPLAKEGNYAIVANVESMDYDPLVVKLNKDISAIEEAMSASLQQHKFQYIFEGLGHLISCILINGAQYFRRIS ESGIKKMCRNIFVLQQNLTNITMSREADLDFARQYYEMLYNTADELLNLVVDQGVKYTELEYIHALTLLHRSQTGVGELTTQNTRLQRLK -------------------------------------------------------------- >In-frame_ENST00000339507_ENST00000253861_TCGA-DX-A7EF-01A_PRMT7_chr16_68380183_+_EXOC4_chr7_133580352_length(transcript)=4443nt_BP=2021nt CTTTGGGGTTCTGTGTGCAGCGAGCATGGTGTCCTTGGCACCAGGGTTTCGGCAGAGGAGCCTAGCGTGGGCCTACTTGGACTCCTCCGC GTGGGGCAGCTCGGGACACCCGGGCCTGCAGGAGAGCGGGGTTCTAGGCTGGCCCCGGCTCTGCAGTGCAGCCGGGTGCCTGCCACTCGC GGGGCTCTGTCGCAGTACTCGTGCCTGGCGCCTCCCCTCAGCCACAGAGACCGCAGTAGCTCCAACCATCGCACCCCTAACTGGGCCACG AGTTCTCTGATTGCCAGACCTGTTGTCTTTGCCACTCACTGTTCTGAGTAATTGGAGAGTCGTGTATTCACTACACGCCAACCAGAGTGG TCCTGTAAAAGCGTAAGCCTAGTGTAGATACGCTTCTGCTTAAAACTCTTGAGTGGCTCCCAGTGCTTTTAGAACAAAATCCAAACGCCT TTCCGAAGTCGACAAGGCCCAGCTTGATTGAGCAGAAGATGTGATAGGAGATGAGGAGCGGGGGGCTTCTGCAAAAGTGCTTCGGTCGCT CAGGCTTTTGGCACATTTTGCTTATGCAACCTAGTTCTTTCTACCTTAGGGCCTTTTCTTGGGAAAGTTGGGAGTCTCACTCTGCTGCCT AGGCTGAGTGCAGTGGTGTGATCGAGGCGCACTGCAGCCTTGACCTCCTGGGCTCAAGCGATCCTCACCTCGGCCTACCGAGTAGCTGGG ACTACAGGCACGCGCCACTACACTCGGATTTCTGACAGTCAGACTTGTCCACAAGAACTCAACTGGCAAGGCTGCTTTTCTGTGCTAAAA CTGGGGAGCTAGTGGGCACCATGAAGATCTTCTGCAGTCGGGCCAATCCGACCACGGGGTCTGTGGAGTGGCTGGAGGAGGATGAACACT ATGATTACCACCAGGAGATTGCAAGGTCATCTTATGCAGATATGCTACATGACAAAGACAGAAATGTAAAATACTACCAAGGTATCCGGG CTGCCGTGAGCAGGGTGAAGGACAGAGGACAGAAGGCCTTGGTTCTCGACATTGGCACTGGCACGGGACTCTTGTCAATGATGGCGGTCA CAGCAGGTGCCGACTTCTGCTATGCCATCGAGGTTTTCAAGCCTATGGCTGATGCTGCTGTGAAGATTGTGGAGAAAAATGGCTTTAGTG ATAAGATTAAGGTTATCAACAAGCATTCCACCGAGGTGACTGTAGGTCCAGAGGGTGACATGCCATGCCGTGCCAACATCCTGGTCACAG AGTTGTTTGACACAGAGCTGATCGGGGAGGGGGCGCTGCCCTCCTATGAGCACGCACACAGGCATCTCGTGGAGGAAAATTGTGAGGCCG TGCCCCACAGAGCCACCGTCTATGCACAGCTGGTGGAGTCCGGGAGGATGTGGTCGTGGAACAAGCTATTTCCCATCCACGTGCAGACCA GCCTCGGAGAGCAGGTCATCGTCCCTCCCGTTGACGTGGAGAGCTGCCCTGGCGCACCCTCTGTCTGTGACATTCAGCTGAACCAGGTGT CACCAGCCGACTTTACAGTCCTCAGCGATGTGCTGCCCATGTTCAGCATAGACTTCAGCAAGCAAGTCAGTAGCTCAGCAGCCTGCCATA GCAGGCGGTTTGAACCTCTGACATCTGGCCGAGCTCAGGTGGTTCTCTCGTGGTGGGACATTGAAATGGACCCTGAGGGGAAGATCAAGT GCACCATGGCCCCCTTCTGGGCACACTCAGACCCAGAGGAGATGCAGTGGCGGGACCACTGGATGCAGTGTGTGTACTTCCTGCCACAAG AGGAGCCTGTGGTGCAGGGCTCAGCGCTCTATCTGGTAGCCCACCACGATGACTACTGCGTATGGTACAGCCTGCAGAGGACCAGCCCTG AAAAGAATGAGAGAGTCCGCCAGATGCGCCCCGTGTGTGACTGCCAGGCTCACCTGCTCTGGAACCGGCCTCGGTTTGGAGAGATCAATG ACCAGGACAGAACTGATCGATACGTCCAGGCTCTGAGGACCAGCACAATCATTGTGGAGAAGACAGTTCAAGACCTCCTGAACCTGATGC ATGACTTGAGTGCATATTCAGATCAATTCCTCAACATGGTGTGCGTGAAGCTCCAGGAGTACAAGGACACCTGCACTGCAGCTTACAGGG GTATTGTCCAGTCAGAAGAAAAACTTGTCATCAGTGCATCCTGGGCAAAAGATGATGATATCAGCAGACTCTTGAAATCTCTACCAAACT GGATGAATATGGCTCAACCCAAACAGCTGAGGCCAAAAAGAGAGGAGGAAGAAGATTTCATAAGGGCAGCTTTTGGCAAGGAGTCTGAAG TTCTTATTGGGAACCTGGGTGATAAATTAATCCCTCCACAAGACATCCTTCGTGACGTCAGTGACCTCAAAGCCTTGGCCAACATGCATG AAAGCCTGGAATGGTTGGCAAGTCGAACAAAGTCAGCTTTCTCCAATCTTTCTACATCCCAGATGCTTTCTCCTGCTCAAGACAGCCACA CGAACACGGATCTCCCCCCAGTGTCAGAGCAGATCATGCAGACTCTCAGTGAACTTGCCAAATCGTTCCAGGATATGGCTGACCGCTGCT TGCTTGTCTTACATCTGGAAGTGAGGGTTCACTGTTTCCACTATCTTATCCCTCTTGCAAAGGAGGGGAACTATGCCATTGTGGCTAATG TGGAAAGTATGGATTATGACCCCCTGGTGGTCAAGCTCAACAAAGATATCAGCGCCATTGAAGAGGCCATGAGCGCCAGCCTTCAGCAGC ACAAGTTCCAGTATATCTTCGAAGGCCTGGGCCACCTGATCTCCTGCATCCTCATTAATGGTGCCCAGTACTTCAGGCGCATCAGTGAGT CTGGCATCAAGAAAATGTGTAGGAACATTTTTGTTCTTCAGCAGAATTTGACCAACATCACCATGTCGCGGGAGGCAGACCTGGACTTTG CAAGGCAGTACTACGAGATGCTTTACAACACAGCTGACGAGCTCCTGAACCTGGTGGTGGACCAGGGTGTGAAGTACACGGAGCTGGAGT ACATCCACGCTCTGACCCTGCTGCACCGCAGCCAGACTGGGGTGGGGGAACTGACCACCCAGAACACGAGGCTGCAGAGGCTCAAAGAGA TCATCTGCGAGCAGGCTGCCATCAAGCAAGCCACCAAGGACAAGAAGATAACTACCGTTTAGCAGGGCGTACTGCGGTTGGTGACGGGGG TCCCCTCAGTCACACTCACTTTTTTCCTTGGTATGTTATTGAGTATATTCTGAGCTTAGTTTTCTCTACAGTGATACTTTAGTGGAGAGG AGGTGTAAGGATTCTTTCTCTCTGGTTTTGGCTTTTCATATAAATGCTAAAGGAAGGCGACAGTACAGAGTGTTTTGGTTGAACAACTAC TTTAATGCAGTCAAATCTAACGGGACTAGGGTGGGATAGGGAGGAAGGTGGTATCAAATTGTTGGACTCTGAAAAACAAGTGGATGGATT ACTAATATTTGATTTATTACTCAATATATATATAATTCCAGCCTTGGAAAGTAGGAAAGTAGGCTGCTACCTAACTTTTAGTCCCTTCCA AAACCATTTAGTAGGGTTCTATTACATAAACAGTAGGGTTTTTCCTCTCCTGACCTTATCCGTTTACAGTTCAATGAAATAAGTGTATGT GCATTGCTGTCTGTCTCTATTGCCAAAATCAAATAAATGGCTTCTCAGCTGCTGTTTACAACAAACTTCCCTAACCAAAACAGAACCTCT AATTTAGGGCTAGGAATAGAAGTCTTTTGATCCCAGTCCCTGGGACAGTTTTGTATGCTGTATCTTGTACACAGGTTGTAGGTTGGTTTA TTGCCATTTTGTTTTATTTCTGCTGTATAAAAACCAAGAGCCAGACAATTAGACAACTATGGAGGAATGAAAGGCAATTCAAACATCTGC TTGATTCCCGCCCCGCCACCCCTAATTTCTGAGAGAATAATGGTTAGAGAACATTGCATCTCACTTGAAACATCCTTTGGGGGTAAATGA TTCTTAGGTGCTCACTTGGTCTGAGCTCAGCTGAATGCAGGGAAGATGGGACAGAGTGACATTTCTCCTCTGTGCGGCCTCCAGCTGAGC CTGTCTCTGAATTGTTCCCTCCCCCGCAATGTGGGCACTTACCATGTTCCTGGCACACTGGACCTCACCATGTCCCCCGGTCACCAGTCC TCTTGCTGCCCATGGTTCATAGGTCATAGAAGGCAGCAATGCACTGACTGGGCCACATCTTGAAAACTCGTGGAAAGGGAAAGGGGAGGA GATGGGACTTTGACCACACACAGTGATGCCTCACACCCTGAAGGTGGGGGATTTTGTACCTGTTTGTACAACTTTGGTCTTGATGGGAAA >In-frame_ENST00000339507_ENST00000253861_TCGA-DX-A7EF-01A_PRMT7_chr16_68380183_+_EXOC4_chr7_133580352_length(amino acids)=815AA_start in transcript=764_stop in transcript=3211 MSTRTQLARLLFCAKTGELVGTMKIFCSRANPTTGSVEWLEEDEHYDYHQEIARSSYADMLHDKDRNVKYYQGIRAAVSRVKDRGQKALV LDIGTGTGLLSMMAVTAGADFCYAIEVFKPMADAAVKIVEKNGFSDKIKVINKHSTEVTVGPEGDMPCRANILVTELFDTELIGEGALPS YEHAHRHLVEENCEAVPHRATVYAQLVESGRMWSWNKLFPIHVQTSLGEQVIVPPVDVESCPGAPSVCDIQLNQVSPADFTVLSDVLPMF SIDFSKQVSSSAACHSRRFEPLTSGRAQVVLSWWDIEMDPEGKIKCTMAPFWAHSDPEEMQWRDHWMQCVYFLPQEEPVVQGSALYLVAH HDDYCVWYSLQRTSPEKNERVRQMRPVCDCQAHLLWNRPRFGEINDQDRTDRYVQALRTSTIIVEKTVQDLLNLMHDLSAYSDQFLNMVC VKLQEYKDTCTAAYRGIVQSEEKLVISASWAKDDDISRLLKSLPNWMNMAQPKQLRPKREEEEDFIRAAFGKESEVLIGNLGDKLIPPQD ILRDVSDLKALANMHESLEWLASRTKSAFSNLSTSQMLSPAQDSHTNTDLPPVSEQIMQTLSELAKSFQDMADRCLLVLHLEVRVHCFHY LIPLAKEGNYAIVANVESMDYDPLVVKLNKDISAIEEAMSASLQQHKFQYIFEGLGHLISCILINGAQYFRRISESGIKKMCRNIFVLQQ NLTNITMSREADLDFARQYYEMLYNTADELLNLVVDQGVKYTELEYIHALTLLHRSQTGVGELTTQNTRLQRLKEIICEQAAIKQATKDK -------------------------------------------------------------- >In-frame_ENST00000339507_ENST00000539845_TCGA-DX-A7EF-01A_PRMT7_chr16_68380183_+_EXOC4_chr7_133580352_length(transcript)=3271nt_BP=2021nt CTTTGGGGTTCTGTGTGCAGCGAGCATGGTGTCCTTGGCACCAGGGTTTCGGCAGAGGAGCCTAGCGTGGGCCTACTTGGACTCCTCCGC GTGGGGCAGCTCGGGACACCCGGGCCTGCAGGAGAGCGGGGTTCTAGGCTGGCCCCGGCTCTGCAGTGCAGCCGGGTGCCTGCCACTCGC GGGGCTCTGTCGCAGTACTCGTGCCTGGCGCCTCCCCTCAGCCACAGAGACCGCAGTAGCTCCAACCATCGCACCCCTAACTGGGCCACG AGTTCTCTGATTGCCAGACCTGTTGTCTTTGCCACTCACTGTTCTGAGTAATTGGAGAGTCGTGTATTCACTACACGCCAACCAGAGTGG TCCTGTAAAAGCGTAAGCCTAGTGTAGATACGCTTCTGCTTAAAACTCTTGAGTGGCTCCCAGTGCTTTTAGAACAAAATCCAAACGCCT TTCCGAAGTCGACAAGGCCCAGCTTGATTGAGCAGAAGATGTGATAGGAGATGAGGAGCGGGGGGCTTCTGCAAAAGTGCTTCGGTCGCT CAGGCTTTTGGCACATTTTGCTTATGCAACCTAGTTCTTTCTACCTTAGGGCCTTTTCTTGGGAAAGTTGGGAGTCTCACTCTGCTGCCT AGGCTGAGTGCAGTGGTGTGATCGAGGCGCACTGCAGCCTTGACCTCCTGGGCTCAAGCGATCCTCACCTCGGCCTACCGAGTAGCTGGG ACTACAGGCACGCGCCACTACACTCGGATTTCTGACAGTCAGACTTGTCCACAAGAACTCAACTGGCAAGGCTGCTTTTCTGTGCTAAAA CTGGGGAGCTAGTGGGCACCATGAAGATCTTCTGCAGTCGGGCCAATCCGACCACGGGGTCTGTGGAGTGGCTGGAGGAGGATGAACACT ATGATTACCACCAGGAGATTGCAAGGTCATCTTATGCAGATATGCTACATGACAAAGACAGAAATGTAAAATACTACCAAGGTATCCGGG CTGCCGTGAGCAGGGTGAAGGACAGAGGACAGAAGGCCTTGGTTCTCGACATTGGCACTGGCACGGGACTCTTGTCAATGATGGCGGTCA CAGCAGGTGCCGACTTCTGCTATGCCATCGAGGTTTTCAAGCCTATGGCTGATGCTGCTGTGAAGATTGTGGAGAAAAATGGCTTTAGTG ATAAGATTAAGGTTATCAACAAGCATTCCACCGAGGTGACTGTAGGTCCAGAGGGTGACATGCCATGCCGTGCCAACATCCTGGTCACAG AGTTGTTTGACACAGAGCTGATCGGGGAGGGGGCGCTGCCCTCCTATGAGCACGCACACAGGCATCTCGTGGAGGAAAATTGTGAGGCCG TGCCCCACAGAGCCACCGTCTATGCACAGCTGGTGGAGTCCGGGAGGATGTGGTCGTGGAACAAGCTATTTCCCATCCACGTGCAGACCA GCCTCGGAGAGCAGGTCATCGTCCCTCCCGTTGACGTGGAGAGCTGCCCTGGCGCACCCTCTGTCTGTGACATTCAGCTGAACCAGGTGT CACCAGCCGACTTTACAGTCCTCAGCGATGTGCTGCCCATGTTCAGCATAGACTTCAGCAAGCAAGTCAGTAGCTCAGCAGCCTGCCATA GCAGGCGGTTTGAACCTCTGACATCTGGCCGAGCTCAGGTGGTTCTCTCGTGGTGGGACATTGAAATGGACCCTGAGGGGAAGATCAAGT GCACCATGGCCCCCTTCTGGGCACACTCAGACCCAGAGGAGATGCAGTGGCGGGACCACTGGATGCAGTGTGTGTACTTCCTGCCACAAG AGGAGCCTGTGGTGCAGGGCTCAGCGCTCTATCTGGTAGCCCACCACGATGACTACTGCGTATGGTACAGCCTGCAGAGGACCAGCCCTG AAAAGAATGAGAGAGTCCGCCAGATGCGCCCCGTGTGTGACTGCCAGGCTCACCTGCTCTGGAACCGGCCTCGGTTTGGAGAGATCAATG ACCAGGACAGAACTGATCGATACGTCCAGGCTCTGAGGACCAGCACAATCATTGTGGAGAAGACAGTTCAAGACCTCCTGAACCTGATGC ATGACTTGAGTGCATATTCAGATCAATTCCTCAACATGGTGTGCGTGAAGCTCCAGGAGTACAAGGACACCTGCACTGCAGCTTACAGGG GTATTGTCCAGTCAGAAGAAAAACTTGTCATCAGTGCATCCTGGGCAAAAGATGATGATATCAGCAGACTCTTGAAATCTCTACCAAACT GGATGAATATGGCTCAACCCAAACAGCTGAGGCCAAAAAGAGAGGAGGAAGAAGATTTCATAAGGGCAGCTTTTGGCAAGGAGTCTGAAG TTCTTATTGGGAACCTGGGTGATAAATTAATCCCTCCACAAGACATCCTTCGTGACGTCAGTGACCTCAAAGCCTTGGCCAACATGCATG AAAGCCTGGAATGGTTGGCAAGTCGAACAAAGTCAGCTTTCTCCAATCTTTCTACATCCCAGATGCTTTCTCCTGCTCAAGACAGCCACA CGAACACGGATCTCCCCCCAGTGTCAGAGCAGATCATGCAGACTCTCAGTGAACTTGCCAAATCGTTCCAGGATATGGCTGACCGCTGCT TGCTTGTCTTACATCTGGAAGTGAGGGTTCACTGTTTCCACTATCTTATCCCTCTTGCAAAGGAGGGGAACTATGCCATTGTGGCTAATG TGGAAAGTATGGATTATGACCCCCTGGTGGTCAAGCTCAACAAAGATATCAGCGCCATTGAAGAGGCCATGAGCGCCAGCCTTCAGCAGC ACAAGTTCCAGTATATCTTCGAAGGCCTGGGCCACCTGATCTCCTGCATCCTCATTAATGGTGCCCAGTACTTCAGGCGCATCAGTGAGT CTGGCATCAAGAAAATGTGTAGGAACATTTTTGTTCTTCAGCAGAATTTGACCAACATCACCATGTCGCGGGAGGCAGACCTGGACTTTG CAAGGCAGTACTACGAGATGCTTTACAACACAGCTGACGAGCTCCTGAACCTGGTGGTGGACCAGGGTGTGAAGTACACGGAGCTGGAGT ACATCCACGCTCTGACCCTGCTGCACCGCAGCCAGACTGGGGTGGGGGAACTGACCACCCAGAACACGAGGCTGCAGAGGCTCAAAGAGA TCATCTGCGAGCAGGCTGCCATCAAGCAAGCCACCAAGGACAAGAAGATAACTACCGTTTAGCAGGGCGTACTGCGGTTGGTGACGGGGG >In-frame_ENST00000339507_ENST00000539845_TCGA-DX-A7EF-01A_PRMT7_chr16_68380183_+_EXOC4_chr7_133580352_length(amino acids)=815AA_start in transcript=764_stop in transcript=3211 MSTRTQLARLLFCAKTGELVGTMKIFCSRANPTTGSVEWLEEDEHYDYHQEIARSSYADMLHDKDRNVKYYQGIRAAVSRVKDRGQKALV LDIGTGTGLLSMMAVTAGADFCYAIEVFKPMADAAVKIVEKNGFSDKIKVINKHSTEVTVGPEGDMPCRANILVTELFDTELIGEGALPS YEHAHRHLVEENCEAVPHRATVYAQLVESGRMWSWNKLFPIHVQTSLGEQVIVPPVDVESCPGAPSVCDIQLNQVSPADFTVLSDVLPMF SIDFSKQVSSSAACHSRRFEPLTSGRAQVVLSWWDIEMDPEGKIKCTMAPFWAHSDPEEMQWRDHWMQCVYFLPQEEPVVQGSALYLVAH HDDYCVWYSLQRTSPEKNERVRQMRPVCDCQAHLLWNRPRFGEINDQDRTDRYVQALRTSTIIVEKTVQDLLNLMHDLSAYSDQFLNMVC VKLQEYKDTCTAAYRGIVQSEEKLVISASWAKDDDISRLLKSLPNWMNMAQPKQLRPKREEEEDFIRAAFGKESEVLIGNLGDKLIPPQD ILRDVSDLKALANMHESLEWLASRTKSAFSNLSTSQMLSPAQDSHTNTDLPPVSEQIMQTLSELAKSFQDMADRCLLVLHLEVRVHCFHY LIPLAKEGNYAIVANVESMDYDPLVVKLNKDISAIEEAMSASLQQHKFQYIFEGLGHLISCILINGAQYFRRISESGIKKMCRNIFVLQQ NLTNITMSREADLDFARQYYEMLYNTADELLNLVVDQGVKYTELEYIHALTLLHRSQTGVGELTTQNTRLQRLKEIICEQAAIKQATKDK -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for PRMT7-EXOC4 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for PRMT7-EXOC4 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for PRMT7-EXOC4 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | PRMT7 | C4310689 | SHORT STATURE, BRACHYDACTYLY, INTELLECTUAL DEVELOPMENTAL DISABILITY, AND SEIZURES | 2 | GENOMICS_ENGLAND;ORPHANET;UNIPROT |
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