|
Fusion Gene Summary | |
Fusion Gene ORF analysis | |
Fusion Genomic Features | |
Fusion Protein Features | |
Fusion Gene Sequence | |
Fusion Gene PPI analysis | |
Related Drugs | |
Related Diseases |
Fusion gene:PTK7-VEGFA (FusionGDB2 ID:69642) |
Fusion Gene Summary for PTK7-VEGFA |
Fusion gene summary |
Fusion gene information | Fusion gene name: PTK7-VEGFA | Fusion gene ID: 69642 | Hgene | Tgene | Gene symbol | PTK7 | VEGFA | Gene ID | 5754 | 7422 |
Gene name | protein tyrosine kinase 7 (inactive) | vascular endothelial growth factor A | |
Synonyms | CCK-4|CCK4 | MVCD1|VEGF|VPF | |
Cytomap | 6p21.1 | 6p21.1 | |
Type of gene | protein-coding | protein-coding | |
Description | inactive tyrosine-protein kinase 7PTK7 protein tyrosine kinase 7colon carcinoma kinase 4pseudo tyrosine kinase receptor 7tyrosine-protein kinase-like 7 | vascular endothelial growth factor Avascular endothelial growth factor A121vascular endothelial growth factor A165vascular permeability factor | |
Modification date | 20200322 | 20200329 | |
UniProtAcc | . | . | |
Ensembl transtripts involved in fusion gene | ENST00000230419, ENST00000349241, ENST00000345201, ENST00000352931, ENST00000481273, ENST00000476760, ENST00000471863, | ENST00000372067, ENST00000417285, ENST00000324450, ENST00000413642, ENST00000372055, ENST00000482630, ENST00000425836, ENST00000372064, ENST00000372077, ENST00000520948, ENST00000523873, ENST00000523950, ENST00000518689, ENST00000523125, ENST00000457104, ENST00000518824, ENST00000230480, | |
Fusion gene scores | * DoF score | 15 X 6 X 10=900 | 10 X 9 X 5=450 |
# samples | 14 | 13 | |
** MAII score | log2(14/900*10)=-2.68449817427207 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(13/450*10)=-1.79141337818858 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
Context | PubMed: PTK7 [Title/Abstract] AND VEGFA [Title/Abstract] AND fusion [Title/Abstract] | ||
Most frequent breakpoint | PTK7(43044305)-VEGFA(43742078), # samples:2 | ||
Anticipated loss of major functional domain due to fusion event. | PTK7-VEGFA seems lost the major protein functional domain in Hgene partner, which is a kinase due to the frame-shifted ORF. PTK7-VEGFA seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF. PTK7-VEGFA seems lost the major protein functional domain in Tgene partner, which is a tumor suppressor due to the frame-shifted ORF. |
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
Partner | Gene | GO ID | GO term | PubMed ID |
Tgene | VEGFA | GO:0000122 | negative regulation of transcription by RNA polymerase II | 18093989 |
Tgene | VEGFA | GO:0001525 | angiogenesis | 11427521|21771332 |
Tgene | VEGFA | GO:0001666 | response to hypoxia | 16490744 |
Tgene | VEGFA | GO:0001934 | positive regulation of protein phosphorylation | 18386220|19033661 |
Tgene | VEGFA | GO:0001938 | positive regulation of endothelial cell proliferation | 9202027|10022831|12714610|16489009|18386220|18577655|20497126 |
Tgene | VEGFA | GO:0002042 | cell migration involved in sprouting angiogenesis | 18059339|20660291 |
Tgene | VEGFA | GO:0002092 | positive regulation of receptor internalization | 20660291 |
Tgene | VEGFA | GO:0008284 | positive regulation of cell proliferation | 7929439 |
Tgene | VEGFA | GO:0008360 | regulation of cell shape | 7929439|10527820 |
Tgene | VEGFA | GO:0010595 | positive regulation of endothelial cell migration | 10022831|19033661 |
Tgene | VEGFA | GO:0010628 | positive regulation of gene expression | 18386220 |
Tgene | VEGFA | GO:0010629 | negative regulation of gene expression | 28977001 |
Tgene | VEGFA | GO:0010749 | regulation of nitric oxide mediated signal transduction | 16150726 |
Tgene | VEGFA | GO:0030224 | monocyte differentiation | 21149635 |
Tgene | VEGFA | GO:0030225 | macrophage differentiation | 21149635 |
Tgene | VEGFA | GO:0030335 | positive regulation of cell migration | 7929439|17470632 |
Tgene | VEGFA | GO:0030949 | positive regulation of vascular endothelial growth factor receptor signaling pathway | 1312256|7929439 |
Tgene | VEGFA | GO:0031334 | positive regulation of protein complex assembly | 16489009|19033661 |
Tgene | VEGFA | GO:0031954 | positive regulation of protein autophosphorylation | 20497126 |
Tgene | VEGFA | GO:0032147 | activation of protein kinase activity | 18059339|20497126 |
Tgene | VEGFA | GO:0032793 | positive regulation of CREB transcription factor activity | 20497126 |
Tgene | VEGFA | GO:0033138 | positive regulation of peptidyl-serine phosphorylation | 18440775|20497126 |
Tgene | VEGFA | GO:0035148 | tube formation | 19033661 |
Tgene | VEGFA | GO:0035767 | endothelial cell chemotaxis | 18440775 |
Tgene | VEGFA | GO:0035924 | cellular response to vascular endothelial growth factor stimulus | 18440775|20497126 |
Tgene | VEGFA | GO:0038033 | positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway | 18440775|20497126|21245381 |
Tgene | VEGFA | GO:0038091 | positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway | 17470632 |
Tgene | VEGFA | GO:0042531 | positive regulation of tyrosine phosphorylation of STAT protein | 19390056 |
Tgene | VEGFA | GO:0043117 | positive regulation of vascular permeability | 26598555 |
Tgene | VEGFA | GO:0043154 | negative regulation of cysteine-type endopeptidase activity involved in apoptotic process | 18386220 |
Tgene | VEGFA | GO:0043406 | positive regulation of MAP kinase activity | 18440775 |
Tgene | VEGFA | GO:0043536 | positive regulation of blood vessel endothelial cell migration | 9202027|18440775|20497126 |
Tgene | VEGFA | GO:0045766 | positive regulation of angiogenesis | 18440775|18577655|19033661|20497126 |
Tgene | VEGFA | GO:0045785 | positive regulation of cell adhesion | 19674970 |
Tgene | VEGFA | GO:0045944 | positive regulation of transcription by RNA polymerase II | 18059339 |
Tgene | VEGFA | GO:0048010 | vascular endothelial growth factor receptor signaling pathway | 21245381 |
Tgene | VEGFA | GO:0050731 | positive regulation of peptidyl-tyrosine phosphorylation | 10022831|16489009|20048167|21245381|26598555 |
Tgene | VEGFA | GO:0050918 | positive chemotaxis | 20497126 |
Tgene | VEGFA | GO:0050927 | positive regulation of positive chemotaxis | 7929439|12744932 |
Tgene | VEGFA | GO:0051272 | positive regulation of cellular component movement | 10527820|12744932 |
Tgene | VEGFA | GO:0051894 | positive regulation of focal adhesion assembly | 16489009 |
Tgene | VEGFA | GO:0071456 | cellular response to hypoxia | 10575000 |
Tgene | VEGFA | GO:0090037 | positive regulation of protein kinase C signaling | 18059339 |
Tgene | VEGFA | GO:0090050 | positive regulation of cell migration involved in sprouting angiogenesis | 20551324 |
Tgene | VEGFA | GO:0097533 | cellular stress response to acid chemical | 26299712 |
Tgene | VEGFA | GO:1900086 | positive regulation of peptidyl-tyrosine autophosphorylation | 20660291 |
Tgene | VEGFA | GO:1900745 | positive regulation of p38MAPK cascade | 18386220 |
Tgene | VEGFA | GO:1901727 | positive regulation of histone deacetylase activity | 20497126 |
Tgene | VEGFA | GO:1903141 | negative regulation of establishment of endothelial barrier | 20048167 |
Tgene | VEGFA | GO:1903392 | negative regulation of adherens junction organization | 26598555 |
Tgene | VEGFA | GO:1903572 | positive regulation of protein kinase D signaling | 20497126 |
Tgene | VEGFA | GO:1903672 | positive regulation of sprouting angiogenesis | 26299712 |
Tgene | VEGFA | GO:2000048 | negative regulation of cell-cell adhesion mediated by cadherin | 26598555 |
Fusion gene breakpoints across PTK7 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
Fusion gene breakpoints across VEGFA (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
ChimerDB4 | PRAD | TCGA-KK-A8ID-01A | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
ChimerDB4 | PRAD | TCGA-KK-A8ID | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Top |
Fusion Gene ORF analysis for PTK7-VEGFA |
Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
Frame-shift | ENST00000230419 | ENST00000372067 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000230419 | ENST00000417285 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000230419 | ENST00000324450 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000230419 | ENST00000413642 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000230419 | ENST00000372055 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000230419 | ENST00000482630 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000230419 | ENST00000425836 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000230419 | ENST00000372064 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000230419 | ENST00000372077 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000230419 | ENST00000520948 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000230419 | ENST00000523873 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000230419 | ENST00000523950 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000230419 | ENST00000518689 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000230419 | ENST00000523125 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000230419 | ENST00000457104 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000230419 | ENST00000518824 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
5CDS-5UTR | ENST00000230419 | ENST00000230480 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000349241 | ENST00000372067 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000349241 | ENST00000417285 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000349241 | ENST00000324450 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000349241 | ENST00000413642 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000349241 | ENST00000372055 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000349241 | ENST00000482630 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000349241 | ENST00000425836 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000349241 | ENST00000372064 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000349241 | ENST00000372077 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000349241 | ENST00000520948 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000349241 | ENST00000523873 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000349241 | ENST00000523950 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000349241 | ENST00000518689 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000349241 | ENST00000523125 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000349241 | ENST00000457104 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000349241 | ENST00000518824 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
5CDS-5UTR | ENST00000349241 | ENST00000230480 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000345201 | ENST00000372067 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000345201 | ENST00000417285 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000345201 | ENST00000324450 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000345201 | ENST00000413642 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000345201 | ENST00000372055 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000345201 | ENST00000482630 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000345201 | ENST00000425836 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000345201 | ENST00000372064 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000345201 | ENST00000372077 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000345201 | ENST00000520948 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000345201 | ENST00000523873 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000345201 | ENST00000523950 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000345201 | ENST00000518689 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000345201 | ENST00000523125 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000345201 | ENST00000457104 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000345201 | ENST00000518824 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
5CDS-5UTR | ENST00000345201 | ENST00000230480 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000352931 | ENST00000372067 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000352931 | ENST00000417285 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000352931 | ENST00000324450 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000352931 | ENST00000413642 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000352931 | ENST00000372055 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000352931 | ENST00000482630 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000352931 | ENST00000425836 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000352931 | ENST00000372064 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000352931 | ENST00000372077 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000352931 | ENST00000520948 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000352931 | ENST00000523873 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000352931 | ENST00000523950 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000352931 | ENST00000518689 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000352931 | ENST00000523125 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000352931 | ENST00000457104 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000352931 | ENST00000518824 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
5CDS-5UTR | ENST00000352931 | ENST00000230480 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
intron-3CDS | ENST00000481273 | ENST00000372067 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
intron-3CDS | ENST00000481273 | ENST00000417285 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
intron-3CDS | ENST00000481273 | ENST00000324450 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
intron-3CDS | ENST00000481273 | ENST00000413642 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
intron-3CDS | ENST00000481273 | ENST00000372055 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
intron-3CDS | ENST00000481273 | ENST00000482630 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
intron-3CDS | ENST00000481273 | ENST00000425836 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
intron-3CDS | ENST00000481273 | ENST00000372064 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
intron-3CDS | ENST00000481273 | ENST00000372077 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
intron-3CDS | ENST00000481273 | ENST00000520948 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
intron-3CDS | ENST00000481273 | ENST00000523873 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
intron-3CDS | ENST00000481273 | ENST00000523950 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
intron-3CDS | ENST00000481273 | ENST00000518689 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
intron-3CDS | ENST00000481273 | ENST00000523125 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
intron-3CDS | ENST00000481273 | ENST00000457104 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
intron-3CDS | ENST00000481273 | ENST00000518824 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
intron-5UTR | ENST00000481273 | ENST00000230480 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000476760 | ENST00000372067 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000476760 | ENST00000417285 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000476760 | ENST00000324450 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000476760 | ENST00000413642 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000476760 | ENST00000372055 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000476760 | ENST00000482630 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000476760 | ENST00000425836 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000476760 | ENST00000372064 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000476760 | ENST00000372077 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000476760 | ENST00000520948 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000476760 | ENST00000523873 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000476760 | ENST00000523950 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000476760 | ENST00000518689 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000476760 | ENST00000523125 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000476760 | ENST00000457104 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000476760 | ENST00000518824 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
5CDS-5UTR | ENST00000476760 | ENST00000230480 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000471863 | ENST00000372067 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000471863 | ENST00000417285 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000471863 | ENST00000324450 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000471863 | ENST00000413642 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000471863 | ENST00000372055 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000471863 | ENST00000482630 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000471863 | ENST00000425836 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000471863 | ENST00000372064 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000471863 | ENST00000372077 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000471863 | ENST00000520948 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000471863 | ENST00000523873 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000471863 | ENST00000523950 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000471863 | ENST00000518689 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000471863 | ENST00000523125 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000471863 | ENST00000457104 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
Frame-shift | ENST00000471863 | ENST00000518824 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
5CDS-5UTR | ENST00000471863 | ENST00000230480 | PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742078 | + |
ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
Top |
Fusion Genomic Features for PTK7-VEGFA |
FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742077 | + | 9.05E-06 | 0.99999094 |
PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742077 | + | 9.05E-06 | 0.99999094 |
PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742077 | + | 9.05E-06 | 0.99999094 |
PTK7 | chr6 | 43044305 | + | VEGFA | chr6 | 43742077 | + | 9.05E-06 | 0.99999094 |
Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
Top |
Fusion Protein Features for PTK7-VEGFA |
Go to FGviewer for the breakpoints of :-: - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. |
Main function of each fusion partner protein. (from UniProt) |
Hgene | Tgene |
. | . |
FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes. | FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes. |
Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
- In-frame and retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
- In-frame and not-retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
Top |
Fusion Gene Sequence for PTK7-VEGFA |
For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
Top |
Fusion Gene PPI Analysis for PTK7-VEGFA |
Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
Hgene | Hgene's interactors | Tgene | Tgene's interactors |
- Retained PPIs in in-frame fusion. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
- Lost PPIs in in-frame fusion. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
- Retained PPIs, but lost function due to frame-shift fusion. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
Top |
Related Drugs for PTK7-VEGFA |
Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
Related Diseases for PTK7-VEGFA |
Diseases associated with fusion partners. (DisGeNet 4.0) |
Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Hgene | PTK7 | C1535926 | Neurodevelopmental Disorders | 1 | CTD_human |
Tgene | VEGFA | C0011570 | Mental Depression | 5 | PSYGENET |
Tgene | VEGFA | C0011581 | Depressive disorder | 5 | PSYGENET |
Tgene | VEGFA | C0151744 | Myocardial Ischemia | 5 | CTD_human |
Tgene | VEGFA | C1269683 | Major Depressive Disorder | 5 | PSYGENET |
Tgene | VEGFA | C0033578 | Prostatic Neoplasms | 4 | CTD_human |
Tgene | VEGFA | C0376358 | Malignant neoplasm of prostate | 4 | CTD_human |
Tgene | VEGFA | C0004096 | Asthma | 3 | CTD_human |
Tgene | VEGFA | C0011884 | Diabetic Retinopathy | 3 | CTD_human |
Tgene | VEGFA | C0027627 | Neoplasm Metastasis | 3 | CTD_human |
Tgene | VEGFA | C0027659 | Neoplasms, Experimental | 3 | CTD_human |
Tgene | VEGFA | C0003865 | Arthritis, Adjuvant-Induced | 2 | CTD_human |
Tgene | VEGFA | C0005586 | Bipolar Disorder | 2 | PSYGENET |
Tgene | VEGFA | C0007137 | Squamous cell carcinoma | 2 | CTD_human |
Tgene | VEGFA | C0010054 | Coronary Arteriosclerosis | 2 | CTD_human |
Tgene | VEGFA | C0018801 | Heart failure | 2 | CTD_human |
Tgene | VEGFA | C0018802 | Congestive heart failure | 2 | CTD_human |
Tgene | VEGFA | C0022660 | Kidney Failure, Acute | 2 | CTD_human |
Tgene | VEGFA | C0023212 | Left-Sided Heart Failure | 2 | CTD_human |
Tgene | VEGFA | C0023893 | Liver Cirrhosis, Experimental | 2 | CTD_human |
Tgene | VEGFA | C0027686 | Pathologic Neovascularization | 2 | CTD_human |
Tgene | VEGFA | C0235527 | Heart Failure, Right-Sided | 2 | CTD_human |
Tgene | VEGFA | C0525045 | Mood Disorders | 2 | PSYGENET |
Tgene | VEGFA | C0971858 | Arthritis, Collagen-Induced | 2 | CTD_human |
Tgene | VEGFA | C0993582 | Arthritis, Experimental | 2 | CTD_human |
Tgene | VEGFA | C1565662 | Acute Kidney Insufficiency | 2 | CTD_human |
Tgene | VEGFA | C1956346 | Coronary Artery Disease | 2 | CTD_human |
Tgene | VEGFA | C1959583 | Myocardial Failure | 2 | CTD_human |
Tgene | VEGFA | C1961112 | Heart Decompensation | 2 | CTD_human |
Tgene | VEGFA | C2609414 | Acute kidney injury | 2 | CTD_human |
Tgene | VEGFA | C0001418 | Adenocarcinoma | 1 | CTD_human |
Tgene | VEGFA | C0002152 | Alloxan Diabetes | 1 | CTD_human |
Tgene | VEGFA | C0002395 | Alzheimer's Disease | 1 | CTD_human |
Tgene | VEGFA | C0003873 | Rheumatoid Arthritis | 1 | CTD_human |
Tgene | VEGFA | C0004153 | Atherosclerosis | 1 | CTD_human |
Tgene | VEGFA | C0006118 | Brain Neoplasms | 1 | CTD_human |
Tgene | VEGFA | C0006826 | Malignant Neoplasms | 1 | CTD_human |
Tgene | VEGFA | C0007102 | Malignant tumor of colon | 1 | CTD_human |
Tgene | VEGFA | C0007131 | Non-Small Cell Lung Carcinoma | 1 | CTD_human |
Tgene | VEGFA | C0007873 | Uterine Cervical Neoplasm | 1 | CTD_human |
Tgene | VEGFA | C0008677 | Bronchitis, Chronic | 1 | CTD_human |
Tgene | VEGFA | C0009375 | Colonic Neoplasms | 1 | CTD_human |
Tgene | VEGFA | C0010398 | Cruveilhier-Baumgarten Syndrome | 1 | CTD_human |
Tgene | VEGFA | C0011265 | Presenile dementia | 1 | CTD_human |
Tgene | VEGFA | C0011616 | Contact Dermatitis | 1 | CTD_human |
Tgene | VEGFA | C0011853 | Diabetes Mellitus, Experimental | 1 | CTD_human |
Tgene | VEGFA | C0011881 | Diabetic Nephropathy | 1 | CTD_human |
Tgene | VEGFA | C0013366 | Dyschondroplasias | 1 | CTD_human |
Tgene | VEGFA | C0014170 | Endometrial Neoplasms | 1 | CTD_human |
Tgene | VEGFA | C0014556 | Epilepsy, Temporal Lobe | 1 | CTD_human |
Tgene | VEGFA | C0014558 | Uncinate Epilepsy | 1 | CTD_human |
Tgene | VEGFA | C0017636 | Glioblastoma | 1 | CTD_human |
Tgene | VEGFA | C0017667 | Nodular glomerulosclerosis | 1 | CTD_human |
Tgene | VEGFA | C0018671 | Head and Neck Neoplasms | 1 | CTD_human |
Tgene | VEGFA | C0018675 | Head Neoplasms | 1 | CTD_human |
Tgene | VEGFA | C0018798 | Congenital Heart Defects | 1 | CTD_human |
Tgene | VEGFA | C0018799 | Heart Diseases | 1 | CTD_human |
Tgene | VEGFA | C0018923 | Hemangiosarcoma | 1 | CTD_human |
Tgene | VEGFA | C0019193 | Hepatitis, Toxic | 1 | CTD_human |
Tgene | VEGFA | C0020541 | Portal Hypertension | 1 | CTD_human |
Tgene | VEGFA | C0021368 | Inflammation | 1 | CTD_human |
Tgene | VEGFA | C0023186 | Learning Disorders | 1 | CTD_human |
Tgene | VEGFA | C0023466 | Leukemia, Monocytic, Chronic | 1 | CTD_human |
Tgene | VEGFA | C0023470 | Myeloid Leukemia | 1 | CTD_human |
Tgene | VEGFA | C0023890 | Liver Cirrhosis | 1 | CTD_human |
Tgene | VEGFA | C0024115 | Lung diseases | 1 | CTD_human |
Tgene | VEGFA | C0024440 | Macular Edema, Cystoid | 1 | CTD_human |
Tgene | VEGFA | C0025237 | Melnick-Needles Syndrome | 1 | CTD_human |
Tgene | VEGFA | C0025261 | Memory Disorders | 1 | CTD_human |
Tgene | VEGFA | C0026760 | Multiple Epiphyseal Dysplasia | 1 | CTD_human |
Tgene | VEGFA | C0027055 | Myocardial Reperfusion Injury | 1 | CTD_human |
Tgene | VEGFA | C0027533 | Neck Neoplasms | 1 | CTD_human |
Tgene | VEGFA | C0027643 | Neoplasm Recurrence, Local | 1 | CTD_human |
Tgene | VEGFA | C0027651 | Neoplasms | 1 | CTD_human |
Tgene | VEGFA | C0029422 | Osteochondrodysplasias | 1 | CTD_human |
Tgene | VEGFA | C0029463 | Osteosarcoma | 1 | CTD_human |
Tgene | VEGFA | C0030246 | Pustulosis of Palms and Soles | 1 | CTD_human |
Tgene | VEGFA | C0032927 | Precancerous Conditions | 1 | CTD_human |
Tgene | VEGFA | C0033687 | Proteinuria | 1 | CTD_human |
Tgene | VEGFA | C0033860 | Psoriasis | 1 | CTD_human |
Tgene | VEGFA | C0035228 | Respiratory Hypersensitivity | 1 | CTD_human |
Tgene | VEGFA | C0035309 | Retinal Diseases | 1 | CTD_human |
Tgene | VEGFA | C0035328 | Retinal Vein Occlusion | 1 | CTD_human |
Tgene | VEGFA | C0035412 | Rhabdomyosarcoma | 1 | CTD_human |
Tgene | VEGFA | C0036391 | Schwartz-Jampel Syndrome | 1 | CTD_human |
Tgene | VEGFA | C0038015 | Spondyloepiphyseal Dysplasia | 1 | CTD_human |
Tgene | VEGFA | C0038220 | Status Epilepticus | 1 | CTD_human |
Tgene | VEGFA | C0038358 | Gastric ulcer | 1 | CTD_human |
Tgene | VEGFA | C0038433 | Streptozotocin Diabetes | 1 | CTD_human |
Tgene | VEGFA | C0042076 | Urologic Neoplasms | 1 | CTD_human |
Tgene | VEGFA | C0085109 | Corneal Neovascularization | 1 | CTD_human |
Tgene | VEGFA | C0085605 | Liver Failure | 1 | CTD_human |
Tgene | VEGFA | C0086692 | Benign Neoplasm | 1 | CTD_human |
Tgene | VEGFA | C0153633 | Malignant neoplasm of brain | 1 | CTD_human |
Tgene | VEGFA | C0162351 | Contact hypersensitivity | 1 | CTD_human |
Tgene | VEGFA | C0178540 | Cerebral Hypoxia-Ischemia | 1 | CTD_human |
Tgene | VEGFA | C0205641 | Adenocarcinoma, Basal Cell | 1 | CTD_human |
Tgene | VEGFA | C0205642 | Adenocarcinoma, Oxyphilic | 1 | CTD_human |
Tgene | VEGFA | C0205643 | Carcinoma, Cribriform | 1 | CTD_human |
Tgene | VEGFA | C0205644 | Carcinoma, Granular Cell | 1 | CTD_human |
Tgene | VEGFA | C0205645 | Adenocarcinoma, Tubular | 1 | CTD_human |
Tgene | VEGFA | C0206726 | gliosarcoma | 1 | CTD_human |
Tgene | VEGFA | C0233794 | Memory impairment | 1 | CTD_human |
Tgene | VEGFA | C0239946 | Fibrosis, Liver | 1 | CTD_human |
Tgene | VEGFA | C0242350 | Erectile dysfunction | 1 | CTD_human |
Tgene | VEGFA | C0242383 | Age related macular degeneration | 1 | CTD_human |
Tgene | VEGFA | C0270823 | Petit mal status | 1 | CTD_human |
Tgene | VEGFA | C0271051 | Macular retinal edema | 1 | CTD_human |
Tgene | VEGFA | C0271178 | Irvine-Gass Syndrome | 1 | CTD_human |
Tgene | VEGFA | C0276496 | Familial Alzheimer Disease (FAD) | 1 | CTD_human |
Tgene | VEGFA | C0278996 | Malignant Head and Neck Neoplasm | 1 | CTD_human |
Tgene | VEGFA | C0282313 | Condition, Preneoplastic | 1 | CTD_human |
Tgene | VEGFA | C0311335 | Grand Mal Status Epilepticus | 1 | CTD_human |
Tgene | VEGFA | C0334588 | Giant Cell Glioblastoma | 1 | CTD_human |
Tgene | VEGFA | C0342257 | Complications of Diabetes Mellitus | 1 | CTD_human |
Tgene | VEGFA | C0393672 | Epilepsy, Benign Psychomotor, Childhood | 1 | CTD_human |
Tgene | VEGFA | C0393682 | Epilepsy, Lateral Temporal | 1 | CTD_human |
Tgene | VEGFA | C0393734 | Complex Partial Status Epilepticus | 1 | CTD_human |
Tgene | VEGFA | C0432272 | Van Buchem disease | 1 | CTD_human |
Tgene | VEGFA | C0476089 | Endometrial Carcinoma | 1 | CTD_human |
Tgene | VEGFA | C0494463 | Alzheimer Disease, Late Onset | 1 | CTD_human |
Tgene | VEGFA | C0496899 | Benign neoplasm of brain, unspecified | 1 | CTD_human |
Tgene | VEGFA | C0546126 | Acute Confusional Senile Dementia | 1 | CTD_human |
Tgene | VEGFA | C0600518 | Choroidal Neovascularization | 1 | CTD_human |
Tgene | VEGFA | C0678807 | prenatal alcohol exposure | 1 | PSYGENET |
Tgene | VEGFA | C0746787 | Cancer of Neck | 1 | CTD_human |
Tgene | VEGFA | C0750900 | Alzheimer's Disease, Focal Onset | 1 | CTD_human |
Tgene | VEGFA | C0750901 | Alzheimer Disease, Early Onset | 1 | CTD_human |
Tgene | VEGFA | C0750974 | Brain Tumor, Primary | 1 | CTD_human |
Tgene | VEGFA | C0750977 | Recurrent Brain Neoplasm | 1 | CTD_human |
Tgene | VEGFA | C0750979 | Primary malignant neoplasm of brain | 1 | CTD_human |
Tgene | VEGFA | C0751177 | Cancer of Head | 1 | CTD_human |
Tgene | VEGFA | C0751262 | Adult Learning Disorders | 1 | CTD_human |
Tgene | VEGFA | C0751263 | Learning Disturbance | 1 | CTD_human |
Tgene | VEGFA | C0751265 | Learning Disabilities | 1 | CTD_human |
Tgene | VEGFA | C0751292 | Age-Related Memory Disorders | 1 | CTD_human |
Tgene | VEGFA | C0751293 | Memory Disorder, Semantic | 1 | CTD_human |
Tgene | VEGFA | C0751294 | Memory Disorder, Spatial | 1 | CTD_human |
Tgene | VEGFA | C0751295 | Memory Loss | 1 | CTD_human |
Tgene | VEGFA | C0751522 | Status Epilepticus, Subclinical | 1 | CTD_human |
Tgene | VEGFA | C0751523 | Non-Convulsive Status Epilepticus | 1 | CTD_human |
Tgene | VEGFA | C0751524 | Simple Partial Status Epilepticus | 1 | CTD_human |
Tgene | VEGFA | C0751571 | Cancer of Urinary Tract | 1 | CTD_human |
Tgene | VEGFA | C0752304 | Hypoxic-Ischemic Encephalopathy | 1 | CTD_human |
Tgene | VEGFA | C0752305 | Anoxic-Ischemic Encephalopathy | 1 | CTD_human |
Tgene | VEGFA | C0752306 | Anoxia-Ischemia, Brain | 1 | CTD_human |
Tgene | VEGFA | C0752307 | Anoxia-Ischemia, Cerebral | 1 | CTD_human |
Tgene | VEGFA | C0752308 | Hypoxia-Ischemia, Brain | 1 | CTD_human |
Tgene | VEGFA | C0860207 | Drug-Induced Liver Disease | 1 | CTD_human |
Tgene | VEGFA | C0887833 | Carcinoma, Pancreatic Ductal | 1 | CTD_human |
Tgene | VEGFA | C0887900 | Upper Aerodigestive Tract Neoplasms | 1 | CTD_human |
Tgene | VEGFA | C1262760 | Hepatitis, Drug-Induced | 1 | CTD_human |
Tgene | VEGFA | C1330966 | Developmental Academic Disorder | 1 | CTD_human |
Tgene | VEGFA | C1527390 | Neoplasms, Intracranial | 1 | CTD_human |
Tgene | VEGFA | C1527411 | Thrombosis of retinal vein | 1 | CTD_human |
Tgene | VEGFA | C1563937 | Atherogenesis | 1 | CTD_human |
Tgene | VEGFA | C1621958 | Glioblastoma Multiforme | 1 | CTD_human |
Tgene | VEGFA | C2063866 | Depressive Disorder, Treatment-Resistant | 1 | PSYGENET |
Tgene | VEGFA | C2717961 | Thrombotic Microangiopathies | 1 | CTD_human |
Tgene | VEGFA | C2931852 | Clear-cell metastatic renal cell carcinoma | 1 | CTD_human |
Tgene | VEGFA | C2937358 | Cerebral Hemorrhage | 1 | CTD_human |
Tgene | VEGFA | C3541456 | Spondyloepiphyseal Dysplasia Tarda, X-Linked | 1 | CTD_human |
Tgene | VEGFA | C3658290 | Drug-Induced Acute Liver Injury | 1 | CTD_human |
Tgene | VEGFA | C4048328 | cervical cancer | 1 | CTD_human |
Tgene | VEGFA | C4277682 | Chemical and Drug Induced Liver Injury | 1 | CTD_human |
Tgene | VEGFA | C4279912 | Chemically-Induced Liver Toxicity | 1 | CTD_human |
Tgene | VEGFA | C4551479 | Schwartz-Jampel Syndrome, Type 1 | 1 | CTD_human |