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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:PTPRF-PHF20 (FusionGDB2 ID:69947)

Fusion Gene Summary for PTPRF-PHF20

check button Fusion gene summary
Fusion gene informationFusion gene name: PTPRF-PHF20
Fusion gene ID: 69947
HgeneTgene
Gene symbol

PTPRF

PHF20

Gene ID

5792

51230

Gene nameprotein tyrosine phosphatase receptor type FPHD finger protein 20
SynonymsBNAH2|LARC20orf104|GLEA2|HCA58|NZF|TDRD20A|TZP
Cytomap

1p34.2

20q11.22-q11.23

Type of geneprotein-codingprotein-coding
Descriptionreceptor-type tyrosine-protein phosphatase FLCA-homologleukocyte antigen-related (LAR) PTP receptorleukocyte antigen-related tyrosine phosphataseleukocyte common antigen relatedprotein tyrosine phosphatase, receptor type, F polypeptidereceptor-linkePHD finger protein 20glioma-expressed antigen 2hepatocellular carcinoma-associated antigen 58novel zinc finger proteintranscription factor TZPtudor domain containing 20A
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000359947, ENST00000438120, 
ENST00000372413, ENST00000372414, 
ENST00000422171, ENST00000496447, 
ENST00000374012, ENST00000439301, 
ENST00000481202, 
Fusion gene scores* DoF score22 X 15 X 12=396026 X 25 X 15=9750
# samples 2432
** MAII scorelog2(24/3960*10)=-4.04439411935845
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(32/9750*10)=-4.92925840863697
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: PTPRF [Title/Abstract] AND PHF20 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointPTPRF(44044591)-PHF20(34487292), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgenePTPRF

GO:0099560

synaptic membrane adhesion

26321637

TgenePHF20

GO:0043981

histone H4-K5 acetylation

20018852

TgenePHF20

GO:0043982

histone H4-K8 acetylation

20018852

TgenePHF20

GO:0043984

histone H4-K16 acetylation

20018852


check buttonFusion gene breakpoints across PTPRF (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across PHF20 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4OVTCGA-61-2111-01APTPRFchr1

44044591

+PHF20chr20

34487292

+
ChimerDB4OVTCGA-61-2111-01APTPRFchr1

44044591

+PHF20chr20

34487292

+


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Fusion Gene ORF analysis for PTPRF-PHF20

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000359947ENST00000374012PTPRFchr1

44044591

+PHF20chr20

34487292

+
5CDS-3UTRENST00000359947ENST00000439301PTPRFchr1

44044591

+PHF20chr20

34487292

+
5CDS-3UTRENST00000359947ENST00000481202PTPRFchr1

44044591

+PHF20chr20

34487292

+
In-frameENST00000438120ENST00000374012PTPRFchr1

44044591

+PHF20chr20

34487292

+
5CDS-3UTRENST00000438120ENST00000439301PTPRFchr1

44044591

+PHF20chr20

34487292

+
5CDS-3UTRENST00000438120ENST00000481202PTPRFchr1

44044591

+PHF20chr20

34487292

+
In-frameENST00000372413ENST00000374012PTPRFchr1

44044591

+PHF20chr20

34487292

+
5CDS-3UTRENST00000372413ENST00000439301PTPRFchr1

44044591

+PHF20chr20

34487292

+
5CDS-3UTRENST00000372413ENST00000481202PTPRFchr1

44044591

+PHF20chr20

34487292

+
In-frameENST00000372414ENST00000374012PTPRFchr1

44044591

+PHF20chr20

34487292

+
5CDS-3UTRENST00000372414ENST00000439301PTPRFchr1

44044591

+PHF20chr20

34487292

+
5CDS-3UTRENST00000372414ENST00000481202PTPRFchr1

44044591

+PHF20chr20

34487292

+
intron-3CDSENST00000422171ENST00000374012PTPRFchr1

44044591

+PHF20chr20

34487292

+
intron-3UTRENST00000422171ENST00000439301PTPRFchr1

44044591

+PHF20chr20

34487292

+
intron-3UTRENST00000422171ENST00000481202PTPRFchr1

44044591

+PHF20chr20

34487292

+
intron-3CDSENST00000496447ENST00000374012PTPRFchr1

44044591

+PHF20chr20

34487292

+
intron-3UTRENST00000496447ENST00000439301PTPRFchr1

44044591

+PHF20chr20

34487292

+
intron-3UTRENST00000496447ENST00000481202PTPRFchr1

44044591

+PHF20chr20

34487292

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000359947PTPRFchr144044591+ENST00000374012PHF20chr2034487292+553010193102775821
ENST00000438120PTPRFchr144044591+ENST00000374012PHF20chr2034487292+551610052962761821
ENST00000372413PTPRFchr144044591+ENST00000374012PHF20chr2034487292+5236725162481821
ENST00000372414PTPRFchr144044591+ENST00000374012PHF20chr2034487292+5236725162481821

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000359947ENST00000374012PTPRFchr144044591+PHF20chr2034487292+0.0020277880.9979722
ENST00000438120ENST00000374012PTPRFchr144044591+PHF20chr2034487292+0.0020274850.99797255
ENST00000372413ENST00000374012PTPRFchr144044591+PHF20chr2034487292+0.0014496780.99855036
ENST00000372414ENST00000374012PTPRFchr144044591+PHF20chr2034487292+0.0014496780.99855036

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Fusion Genomic Features for PTPRF-PHF20


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
PTPRFchr144044591+PHF20chr2034487291+2.20E-050.99997807
PTPRFchr144044591+PHF20chr2034487291+2.20E-050.99997807

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for PTPRF-PHF20


check button Go to

FGviewer for the breakpoints of chr1:44044591-chr20:34487292

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePTPRFchr1:44044591chr20:34487292ENST00000359947+734135_224226.333333333333341908.0DomainNote=Ig-like C2-type 2
HgenePTPRFchr1:44044591chr20:34487292ENST00000359947+73433_123226.333333333333341908.0DomainNote=Ig-like C2-type 1
HgenePTPRFchr1:44044591chr20:34487292ENST00000372413+531135_224226.333333333333341899.0DomainNote=Ig-like C2-type 2
HgenePTPRFchr1:44044591chr20:34487292ENST00000372413+53133_123226.333333333333341899.0DomainNote=Ig-like C2-type 1
HgenePTPRFchr1:44044591chr20:34487292ENST00000372414+532135_224226.333333333333341908.0DomainNote=Ig-like C2-type 2
HgenePTPRFchr1:44044591chr20:34487292ENST00000372414+53233_123226.333333333333341908.0DomainNote=Ig-like C2-type 1
HgenePTPRFchr1:44044591chr20:34487292ENST00000438120+733135_224226.333333333333341899.0DomainNote=Ig-like C2-type 2
HgenePTPRFchr1:44044591chr20:34487292ENST00000438120+73333_123226.333333333333341899.0DomainNote=Ig-like C2-type 1
HgenePTPRFchr1:44044591chr20:34487292ENST00000359947+73468_77226.333333333333341908.0RegionHeparin-binding
HgenePTPRFchr1:44044591chr20:34487292ENST00000372413+53168_77226.333333333333341899.0RegionHeparin-binding
HgenePTPRFchr1:44044591chr20:34487292ENST00000372414+53268_77226.333333333333341908.0RegionHeparin-binding
HgenePTPRFchr1:44044591chr20:34487292ENST00000438120+73368_77226.333333333333341899.0RegionHeparin-binding
TgenePHF20chr1:44044591chr20:34487292ENST00000374012818523_552427.33333333333331013.0Compositional biasNote=Lys-rich
TgenePHF20chr1:44044591chr20:34487292ENST00000439301919523_552405.66666666666671356.0Compositional biasNote=Lys-rich
TgenePHF20chr1:44044591chr20:34487292ENST00000374012818452_477427.33333333333331013.0Zinc fingerC2H2-type
TgenePHF20chr1:44044591chr20:34487292ENST00000374012818654_700427.33333333333331013.0Zinc fingerNote=PHD-type
TgenePHF20chr1:44044591chr20:34487292ENST00000439301919452_477405.66666666666671356.0Zinc fingerC2H2-type
TgenePHF20chr1:44044591chr20:34487292ENST00000439301919654_700405.66666666666671356.0Zinc fingerNote=PHD-type

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePTPRFchr1:44044591chr20:34487292ENST00000359947+7341014_1098226.333333333333341908.0DomainFibronectin type-III 8
HgenePTPRFchr1:44044591chr20:34487292ENST00000359947+7341352_1607226.333333333333341908.0DomainTyrosine-protein phosphatase 1
HgenePTPRFchr1:44044591chr20:34487292ENST00000359947+7341639_1898226.333333333333341908.0DomainTyrosine-protein phosphatase 2
HgenePTPRFchr1:44044591chr20:34487292ENST00000359947+734232_314226.333333333333341908.0DomainNote=Ig-like C2-type 3
HgenePTPRFchr1:44044591chr20:34487292ENST00000359947+734321_411226.333333333333341908.0DomainFibronectin type-III 1
HgenePTPRFchr1:44044591chr20:34487292ENST00000359947+734416_510226.333333333333341908.0DomainFibronectin type-III 2
HgenePTPRFchr1:44044591chr20:34487292ENST00000359947+734514_604226.333333333333341908.0DomainFibronectin type-III 3
HgenePTPRFchr1:44044591chr20:34487292ENST00000359947+734609_706226.333333333333341908.0DomainFibronectin type-III 4
HgenePTPRFchr1:44044591chr20:34487292ENST00000359947+734711_819226.333333333333341908.0DomainFibronectin type-III 5
HgenePTPRFchr1:44044591chr20:34487292ENST00000359947+734820_914226.333333333333341908.0DomainFibronectin type-III 6
HgenePTPRFchr1:44044591chr20:34487292ENST00000359947+734918_1010226.333333333333341908.0DomainFibronectin type-III 7
HgenePTPRFchr1:44044591chr20:34487292ENST00000372413+5311014_1098226.333333333333341899.0DomainFibronectin type-III 8
HgenePTPRFchr1:44044591chr20:34487292ENST00000372413+5311352_1607226.333333333333341899.0DomainTyrosine-protein phosphatase 1
HgenePTPRFchr1:44044591chr20:34487292ENST00000372413+5311639_1898226.333333333333341899.0DomainTyrosine-protein phosphatase 2
HgenePTPRFchr1:44044591chr20:34487292ENST00000372413+531232_314226.333333333333341899.0DomainNote=Ig-like C2-type 3
HgenePTPRFchr1:44044591chr20:34487292ENST00000372413+531321_411226.333333333333341899.0DomainFibronectin type-III 1
HgenePTPRFchr1:44044591chr20:34487292ENST00000372413+531416_510226.333333333333341899.0DomainFibronectin type-III 2
HgenePTPRFchr1:44044591chr20:34487292ENST00000372413+531514_604226.333333333333341899.0DomainFibronectin type-III 3
HgenePTPRFchr1:44044591chr20:34487292ENST00000372413+531609_706226.333333333333341899.0DomainFibronectin type-III 4
HgenePTPRFchr1:44044591chr20:34487292ENST00000372413+531711_819226.333333333333341899.0DomainFibronectin type-III 5
HgenePTPRFchr1:44044591chr20:34487292ENST00000372413+531820_914226.333333333333341899.0DomainFibronectin type-III 6
HgenePTPRFchr1:44044591chr20:34487292ENST00000372413+531918_1010226.333333333333341899.0DomainFibronectin type-III 7
HgenePTPRFchr1:44044591chr20:34487292ENST00000372414+5321014_1098226.333333333333341908.0DomainFibronectin type-III 8
HgenePTPRFchr1:44044591chr20:34487292ENST00000372414+5321352_1607226.333333333333341908.0DomainTyrosine-protein phosphatase 1
HgenePTPRFchr1:44044591chr20:34487292ENST00000372414+5321639_1898226.333333333333341908.0DomainTyrosine-protein phosphatase 2
HgenePTPRFchr1:44044591chr20:34487292ENST00000372414+532232_314226.333333333333341908.0DomainNote=Ig-like C2-type 3
HgenePTPRFchr1:44044591chr20:34487292ENST00000372414+532321_411226.333333333333341908.0DomainFibronectin type-III 1
HgenePTPRFchr1:44044591chr20:34487292ENST00000372414+532416_510226.333333333333341908.0DomainFibronectin type-III 2
HgenePTPRFchr1:44044591chr20:34487292ENST00000372414+532514_604226.333333333333341908.0DomainFibronectin type-III 3
HgenePTPRFchr1:44044591chr20:34487292ENST00000372414+532609_706226.333333333333341908.0DomainFibronectin type-III 4
HgenePTPRFchr1:44044591chr20:34487292ENST00000372414+532711_819226.333333333333341908.0DomainFibronectin type-III 5
HgenePTPRFchr1:44044591chr20:34487292ENST00000372414+532820_914226.333333333333341908.0DomainFibronectin type-III 6
HgenePTPRFchr1:44044591chr20:34487292ENST00000372414+532918_1010226.333333333333341908.0DomainFibronectin type-III 7
HgenePTPRFchr1:44044591chr20:34487292ENST00000438120+7331014_1098226.333333333333341899.0DomainFibronectin type-III 8
HgenePTPRFchr1:44044591chr20:34487292ENST00000438120+7331352_1607226.333333333333341899.0DomainTyrosine-protein phosphatase 1
HgenePTPRFchr1:44044591chr20:34487292ENST00000438120+7331639_1898226.333333333333341899.0DomainTyrosine-protein phosphatase 2
HgenePTPRFchr1:44044591chr20:34487292ENST00000438120+733232_314226.333333333333341899.0DomainNote=Ig-like C2-type 3
HgenePTPRFchr1:44044591chr20:34487292ENST00000438120+733321_411226.333333333333341899.0DomainFibronectin type-III 1
HgenePTPRFchr1:44044591chr20:34487292ENST00000438120+733416_510226.333333333333341899.0DomainFibronectin type-III 2
HgenePTPRFchr1:44044591chr20:34487292ENST00000438120+733514_604226.333333333333341899.0DomainFibronectin type-III 3
HgenePTPRFchr1:44044591chr20:34487292ENST00000438120+733609_706226.333333333333341899.0DomainFibronectin type-III 4
HgenePTPRFchr1:44044591chr20:34487292ENST00000438120+733711_819226.333333333333341899.0DomainFibronectin type-III 5
HgenePTPRFchr1:44044591chr20:34487292ENST00000438120+733820_914226.333333333333341899.0DomainFibronectin type-III 6
HgenePTPRFchr1:44044591chr20:34487292ENST00000438120+733918_1010226.333333333333341899.0DomainFibronectin type-III 7
HgenePTPRFchr1:44044591chr20:34487292ENST00000359947+7341548_1554226.333333333333341908.0RegionSubstrate binding
HgenePTPRFchr1:44044591chr20:34487292ENST00000372413+5311548_1554226.333333333333341899.0RegionSubstrate binding
HgenePTPRFchr1:44044591chr20:34487292ENST00000372414+5321548_1554226.333333333333341908.0RegionSubstrate binding
HgenePTPRFchr1:44044591chr20:34487292ENST00000438120+7331548_1554226.333333333333341899.0RegionSubstrate binding
HgenePTPRFchr1:44044591chr20:34487292ENST00000359947+7341285_1907226.333333333333341908.0Topological domainCytoplasmic
HgenePTPRFchr1:44044591chr20:34487292ENST00000359947+73430_1263226.333333333333341908.0Topological domainExtracellular
HgenePTPRFchr1:44044591chr20:34487292ENST00000372413+5311285_1907226.333333333333341899.0Topological domainCytoplasmic
HgenePTPRFchr1:44044591chr20:34487292ENST00000372413+53130_1263226.333333333333341899.0Topological domainExtracellular
HgenePTPRFchr1:44044591chr20:34487292ENST00000372414+5321285_1907226.333333333333341908.0Topological domainCytoplasmic
HgenePTPRFchr1:44044591chr20:34487292ENST00000372414+53230_1263226.333333333333341908.0Topological domainExtracellular
HgenePTPRFchr1:44044591chr20:34487292ENST00000438120+7331285_1907226.333333333333341899.0Topological domainCytoplasmic
HgenePTPRFchr1:44044591chr20:34487292ENST00000438120+73330_1263226.333333333333341899.0Topological domainExtracellular
HgenePTPRFchr1:44044591chr20:34487292ENST00000359947+7341264_1284226.333333333333341908.0TransmembraneHelical
HgenePTPRFchr1:44044591chr20:34487292ENST00000372413+5311264_1284226.333333333333341899.0TransmembraneHelical
HgenePTPRFchr1:44044591chr20:34487292ENST00000372414+5321264_1284226.333333333333341908.0TransmembraneHelical
HgenePTPRFchr1:44044591chr20:34487292ENST00000438120+7331264_1284226.333333333333341899.0TransmembraneHelical
TgenePHF20chr1:44044591chr20:34487292ENST00000374012818162_221427.33333333333331013.0Compositional biasNote=Lys-rich
TgenePHF20chr1:44044591chr20:34487292ENST00000439301919162_221405.66666666666671356.0Compositional biasNote=Lys-rich
TgenePHF20chr1:44044591chr20:34487292ENST00000374012818257_269427.33333333333331013.0DNA bindingNote=A.T hook
TgenePHF20chr1:44044591chr20:34487292ENST00000439301919257_269405.66666666666671356.0DNA bindingNote=A.T hook
TgenePHF20chr1:44044591chr20:34487292ENST000003740128184_69427.33333333333331013.0DomainNote=Tudor 1
TgenePHF20chr1:44044591chr20:34487292ENST0000037401281883_147427.33333333333331013.0DomainNote=Tudor 2
TgenePHF20chr1:44044591chr20:34487292ENST000004393019194_69405.66666666666671356.0DomainNote=Tudor 1
TgenePHF20chr1:44044591chr20:34487292ENST0000043930191983_147405.66666666666671356.0DomainNote=Tudor 2


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Fusion Gene Sequence for PTPRF-PHF20


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000359947_ENST00000374012_TCGA-61-2111-01A_PTPRF_chr1_44044591_+_PHF20_chr20_34487292_length(transcript)=5530nt_BP=1019nt
CGGGAGCGGCGGGAGCGGTGGCGGCGGCAGAGGCGGCGGCTCCAGCTTCGGCTCCGGCTCGGGCTCGGGCTCCGGCTCCGGCTCCGGCTC
CGGCTCCAGCTCGGGTGGCGGTGGCGGGAGCGGGACCAGGTGGAGGCGGCGGCGGCAGAGGAGTGGGAGCAGCGGCCCTAGCGGCTTGCG
GGGGGACATGCGGACCGACGGCCCCTGGATAGGCGGAAGGAGTGGAGGCCCTGGTGCCCGGCCCTTGGTGCTGAGTATCCAGCAAGAGTG
ACCGGGGTGAAGAAGCAAAGACTCGGTTGATTGTCCTGGGCTGTGGCTGGCTGTGGAGCTAGAGCCCTGGATGGCCCCTGAGCCAGCCCC
AGGGAGGACGATGGTGCCCCTTGTGCCTGCACTGGTGATGCTTGGTTTGGTGGCAGGCGCCCATGGTGACAGCAAACCTGTCTTCATTAA
AGTCCCTGAGGACCAGACTGGGCTGTCAGGAGGGGTAGCCTCCTTCGTGTGCCAAGCTACAGGAGAACCCAAGCCGCGCATCACATGGAT
GAAGAAGGGGAAGAAAGTCAGCTCCCAGCGCTTCGAGGTCATTGAGTTTGATGATGGGGCAGGGTCAGTGCTTCGGATCCAGCCATTGCG
GGTGCAGCGAGATGAAGCCATCTATGAGTGTACAGCTACTAACAGCCTGGGTGAGATCAACACTAGTGCCAAGCTCTCAGTGCTCGAAGA
GGAACAGCTGCCCCCTGGGTTCCCTTCCATCGACATGGGGCCTCAGCTGAAGGTGGTGGAGAAGGCACGCACAGCCACCATGCTATGTGC
CGCAGGCGGAAATCCAGACCCTGAGATTTCTTGGTTCAAGGACTTCCTTCCTGTAGACCCTGCCACGAGCAACGGCCGCATCAAGCAGCT
GCGTTCAGGTGCCTTGCAGATAGAGAGCAGTGAGGAATCCGACCAAGGCAAGTACGAGTGTGTGGCGACCAACTCGGCAGGCACACGTTA
CTCAGCCCCTGCGAACCTGTATGTGCGAGTAACAAATACTTTTAAGAAAACAGATGATTTTGGGTCATCTAATGCACCAGCTGTCGACCT
AGACCATAAGTTTAGATGCAAAGTTGTGGACTGTTTAAAATTTTTCCGCAAAGCCAAACTGTTGCACTATCACATGAAGTATTTCCATGG
AATGGAGAAGTCACTGGAGCCAGAAGAGAGCCCGGGAAAGAGGCATGTCCAAACCAGGGGCCCTTCAGCTTCAGACAAGCCCAGCCAGGA
GACCCTGACCAGGAAGCGGGTCTCTGCCAGTTCCCCAACTACAAAAGACAAGGAAAAGAATAAAGAGAAGAAATTCAAGGAGTTTGTGAG
AGTGAAGCCAAAGAAGAAAAAGAAAAAGAAAAAGAAAACCAAACCTGAATGCCCCTGCAGTGAGGAGATCAGTGACACCTCCCAGGAACC
TTCTCCACCCAAGGCATTTGCTGTTACCAGGTGTGGGTCCTCACACAAGCCAGGGGTCCATATGAGCCCGCAGCTTCATGGCCCAGAATC
TGGACACCACAAAGGGAAAGTGAAAGCATTGGAGGAGGATAATTTGAGTGAGTCCTCTTCTGAGAGCTTTCTCTGGAGTGATGATGAGTA
TGGCCAAGATGTGGATGTGACCACCAACCCAGATGAGGAACTTGATGGGGATGACCGCTATGACTTCGAGGTGGTCCGCTGCATCTGTGA
GGTCCAGGAGGAAAATGACTTCATGATTCAGTGTGAAGAGTGCCAGTGCTGGCAGCATGGGGTCTGCATGGGATTACTGGAAGAAAATGT
GCCCGAGAAATACACCTGTTATGTTTGCCAAGACCCTCCAGGTCAGAGGCCTGGCTTCAAGTACTGGTATGACAAGGAGTGGCTGAGCAG
GGGACATATGCATGGCCTGGCATTTCTAGAAGAGAACTACTCCCATCAGAATGCCAAGAAGATCGTGGCCACCCACCAGCTTCTTGGTGA
TGTGCAGAGAGTGATTGAGGTTCTGCATGGCCTGCAGCTCAAGATGAGCATCTTGCAAAGCCGGGAGCATCCTGATCTGCCGCTGTGGTG
CCAGCCTTGGAAACAGCACTCAGGGGAGGGGAGATCTCATTTCAGAAACATCCCTGTCACTGACACCAGGAGCAAGGAGGAAGCTCCAAG
CTATAGAACTTTGAACGGGGCAGTGGAGAAGCCCAGGCCCCTGGCCCTGCCCCTGCCGCGTTCTGTGGAGGAATCCTATATCACCAGTGA
GCATTGCTACCAGAAGCCCCGCGCCTATTACCCTGCCGTGGAGCAGAAGCTGGTGGTGGAGACGAGGGGCTCTGCCCTCGACGATGCGGT
CAACCCCCTCCATGAGAACGGCGATGATTCCCTTTCCCCGCGCCTGGGCTGGCCTCTAGACCAAGACAGGAGCAAGGGGGACAGTGACCC
CAAACCCGGCTCCCCAAAGGTGAAGGAATATGTCTCCAAAAAGGCCCTACCAGAAGAAGCCCCTGCTCGGAAGCTGCTGGACAGAGGTGG
AGAGGGGCTGCTGAGCTCCCAGCACCAGTGGCAGTTTAACCTGCTGACCCATGTGGAATCTCTTCAGGATGAAGTTACGCACAGGATGGA
CTCCATTGAGAAGGAGTTGGATGTGTTGGAGAGCTGGCTGGACTACACTGGGGAACTGGAGCCCCCTGAGCCGCTGGCCAGGCTTCCGCA
GCTCAAGCATTGTATCAAGCAGCTGCTGATGGACCTGGGCAAGGTGCAGCAGATCGCCCTCTGCTGCTCAACATGAAACTGGGCACCCAA
AACTCATGGGGGCACAATCCTGGGGCACCTGCAGGAGGAGCTTCGCATATTTAAATAAATAAACCTAGCATGCTGAATGCACGTGACACC
GACTGACTTCAGGGATCTGGGCCAGGAGTGTGGTGGACATTGGACAAAGAGGCCATTTTGGCTGCGGGAGGACACTCTGATCTCGAAGCC
TGCCATAAAGGTAGCAAATAGACTCTTGGGATTCCCCTCTTCTGTGCACATCGTTGAATGAAGAGAGTCTTTTTGCACAAACTTCACTTG
AAATTGTGCCACTGATGATAAACGGAATGAGAGCCAAAAAAGTTTAGTTGGAGACAGTTGTAAATTCAATTTGGAGTTTATTTAATTGAC
TTTTCTATCACGTTGGGGCACATGCCAACTCCCTGGTTTCTTCCTGGCATGGTGTTTGGGCAGCAGGCATCATTTTCCTTTTCTAGCTTC
ATAGGAATATTGTGAGCTCACCATGCTGTGGAGGTTGGGAAAGAGCAGAGTCTTGGCTGCCCTGCTTTCTCCTTAGGACTCTTCACTTTT
CTCACCACATCTCTTGCATGACTTCATGGTACTGGGGACAAGTTTGTATGCCTTCACCCCAGAGCTGGCTGGGTTATGGCTTTTGTAGCA
GAGCCCATACAGCCTATGGAAGAACTAGAATCTCACTCACAGTAATAAGAATCTAGGAGGAATTCCAAACCGAAGCAGGCAGGGTCTGGA
ACCCAAAGGACAGCATTTTCTACCCACTTCTTAATATTGACAGCTTCCCCGTTCTATTTAATGTCCAAAAATGTTTCCCAAAATTTCAAA
CTCTTTCACTGTAAAGATTTGTTACAAAGAATGTGGTTTGGGGAATTACCTTATTTTATATTGTTGTAAACAAACTTCAAATTCTACATG
TGCGACTTTTCTCCTTCCTGAAGGGTGTTTAGTAGTCAGCGTTTTCAGAATTGTTTTGTTACTATACTTTAACATTTTACATTTCCTGTT
TGTATTATTTTGTGAGAGCAAGGTGATCATGCTGCTTAAGGTCCAGGTACAACCTATTTGTACCTTTTGAGACAATATTTGTGTTACTTT
TGCAGGTTACGGTTCCACATGTAATTGCTATATTTTGTTTTGTTTTTCCTTACTAGGCAAAGTTAAAATGTTCCATGCTTTGAGGAGTGA
CCCATTTCACTACTTTGTTTTCTTATCACTAAAGGCAAAAATCAAAGCACAGTTGTCCATTAACACTTATAAGTTAATTATGGGTTTATG
AGTCTGTAATGTTATATGCTGCAAACATTTACTATGTAAACGTGAAGTAGCCAATAATATCTCAATAGTAGTAACAGTATCTTTAGCGAC
CTTTGGAATAGTTAAGCACAGGTCATTGTGGACATGAATTCAGGCCTCTGTACTAAAATCTATTTCAGGGAATGTTCTGTCTAGTGATTT
GCTCACCATTTGATATATAATGAATTATAGGACAAGTATAAGCTGATCTGCTATAGCTGTCCATCAGAGAGAATACACGTGGCTATAACA
TCTATAACAAAACGACGATTCCTCTACAAGAGGCTGTTTCTCACTGCTAACGTTGGTGTTTCTGGCGTGGGAAGAAATGCACAGGCGTGC
ATGGCATGCACGTTCAGACAGCTGCATTGTAAGAGTTCTGTCATGCAGTCTGAAAAGGGAAGAAACAGGATGGCTTTCTGTAGCCACACC
TGTGAGGCGTGATGATTGTTGTATTATTAGATTACTGATTTTTCTTTTCTGAAAATACATTTGAGTTTTAATCACATCTGTGGAAGCTGT
AACTTTTAAGGTAGTCAATTTCATGTCTTGTTCAACGATGTAAGCAGAAACTGAATTGCCCTAATTTTGCCAACTGGCCATTATTGGGAT
TATTGTTTAAATTTTTGGTAAAGGAAGTAATCTCCTTTCATTCATTGTGACTTTTGTTCTTAGGGAAGCAGAGAAGACTCCCCAAGTTCT
TATAACCTCATTGTGCTTCCCTAATTTAAAGCCATGTTGAGGGGCTCCATTCCCAATTCCTGGGTCAAGGTGAATTAACCCTATGTTGGA
GCACTGGAAACCGTTATTTGCAAACATTGCTGTTACCATTTAGAAATATGTGCACTATCAGCTGGGTGCAGTGGCTCACGTCTGTAATCC
CAGCACTTTGGGAGGCCGAGGCAGGTGGATCACCTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACAGGGTGAAACCCCGTCTCTACTA
AAAGTACAAAAATTAGCTGGGCGTGGTGGCGGACGCCTGTAATCTCAGCTACTTGGGAGGCTGAAGCAGGAGAGGTGCTGGAACCTGGGA
GGCGGAGGTTGAAGTGAGCCGAGATTGCGCTATTGCACTCCAGCTCGGGCGACAACTGCAAGACTCCATCTCAAAAAAATAAAAATAAAA
GAAAAGAAAGAAATATGTGCACTACCTAAGTTTTGTCTTTAGAAAAACTATCCACCTATAAAAAATTACCTTGACAAAAATAGTTCCGGT
TTGACTAATCATTTTGTTTCTTTAAGTGGTAAGTGTATGCAAGGTGGATCCTTGATGAGCCAACATTGCACTGTGGATACATATCTATGT
TTACGCGCTATTAGAACAGAAGGCGCTGTATATAGAAATGTTGCTTTGAAGCAATATTTGCAAAACACGCAGACTTCTGTATCTGTATTT

>In-frame_ENST00000359947_ENST00000374012_TCGA-61-2111-01A_PTPRF_chr1_44044591_+_PHF20_chr20_34487292_length(amino acids)=821AA_start in transcript=310_stop in transcript=2775
MWLAVELEPWMAPEPAPGRTMVPLVPALVMLGLVAGAHGDSKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEV
IEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNPDPEISWFK
DFLPVDPATSNGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPANLYVRVTNTFKKTDDFGSSNAPAVDLDHKFRCKVVDCLK
FFRKAKLLHYHMKYFHGMEKSLEPEESPGKRHVQTRGPSASDKPSQETLTRKRVSASSPTTKDKEKNKEKKFKEFVRVKPKKKKKKKKKT
KPECPCSEEISDTSQEPSPPKAFAVTRCGSSHKPGVHMSPQLHGPESGHHKGKVKALEEDNLSESSSESFLWSDDEYGQDVDVTTNPDEE
LDGDDRYDFEVVRCICEVQEENDFMIQCEECQCWQHGVCMGLLEENVPEKYTCYVCQDPPGQRPGFKYWYDKEWLSRGHMHGLAFLEENY
SHQNAKKIVATHQLLGDVQRVIEVLHGLQLKMSILQSREHPDLPLWCQPWKQHSGEGRSHFRNIPVTDTRSKEEAPSYRTLNGAVEKPRP
LALPLPRSVEESYITSEHCYQKPRAYYPAVEQKLVVETRGSALDDAVNPLHENGDDSLSPRLGWPLDQDRSKGDSDPKPGSPKVKEYVSK
KALPEEAPARKLLDRGGEGLLSSQHQWQFNLLTHVESLQDEVTHRMDSIEKELDVLESWLDYTGELEPPEPLARLPQLKHCIKQLLMDLG

--------------------------------------------------------------
>In-frame_ENST00000438120_ENST00000374012_TCGA-61-2111-01A_PTPRF_chr1_44044591_+_PHF20_chr20_34487292_length(transcript)=5516nt_BP=1005nt
GCGGTGGCGGCGGCAGAGGCGGCGGCTCCAGCTTCGGCTCCGGCTCGGGCTCGGGCTCCGGCTCCGGCTCCGGCTCCGGCTCCAGCTCGG
GTGGCGGTGGCGGGAGCGGGACCAGGTGGAGGCGGCGGCGGCAGAGGAGTGGGAGCAGCGGCCCTAGCGGCTTGCGGGGGGACATGCGGA
CCGACGGCCCCTGGATAGGCGGAAGGAGTGGAGGCCCTGGTGCCCGGCCCTTGGTGCTGAGTATCCAGCAAGAGTGACCGGGGTGAAGAA
GCAAAGACTCGGTTGATTGTCCTGGGCTGTGGCTGGCTGTGGAGCTAGAGCCCTGGATGGCCCCTGAGCCAGCCCCAGGGAGGACGATGG
TGCCCCTTGTGCCTGCACTGGTGATGCTTGGTTTGGTGGCAGGCGCCCATGGTGACAGCAAACCTGTCTTCATTAAAGTCCCTGAGGACC
AGACTGGGCTGTCAGGAGGGGTAGCCTCCTTCGTGTGCCAAGCTACAGGAGAACCCAAGCCGCGCATCACATGGATGAAGAAGGGGAAGA
AAGTCAGCTCCCAGCGCTTCGAGGTCATTGAGTTTGATGATGGGGCAGGGTCAGTGCTTCGGATCCAGCCATTGCGGGTGCAGCGAGATG
AAGCCATCTATGAGTGTACAGCTACTAACAGCCTGGGTGAGATCAACACTAGTGCCAAGCTCTCAGTGCTCGAAGAGGAACAGCTGCCCC
CTGGGTTCCCTTCCATCGACATGGGGCCTCAGCTGAAGGTGGTGGAGAAGGCACGCACAGCCACCATGCTATGTGCCGCAGGCGGAAATC
CAGACCCTGAGATTTCTTGGTTCAAGGACTTCCTTCCTGTAGACCCTGCCACGAGCAACGGCCGCATCAAGCAGCTGCGTTCAGGTGCCT
TGCAGATAGAGAGCAGTGAGGAATCCGACCAAGGCAAGTACGAGTGTGTGGCGACCAACTCGGCAGGCACACGTTACTCAGCCCCTGCGA
ACCTGTATGTGCGAGTAACAAATACTTTTAAGAAAACAGATGATTTTGGGTCATCTAATGCACCAGCTGTCGACCTAGACCATAAGTTTA
GATGCAAAGTTGTGGACTGTTTAAAATTTTTCCGCAAAGCCAAACTGTTGCACTATCACATGAAGTATTTCCATGGAATGGAGAAGTCAC
TGGAGCCAGAAGAGAGCCCGGGAAAGAGGCATGTCCAAACCAGGGGCCCTTCAGCTTCAGACAAGCCCAGCCAGGAGACCCTGACCAGGA
AGCGGGTCTCTGCCAGTTCCCCAACTACAAAAGACAAGGAAAAGAATAAAGAGAAGAAATTCAAGGAGTTTGTGAGAGTGAAGCCAAAGA
AGAAAAAGAAAAAGAAAAAGAAAACCAAACCTGAATGCCCCTGCAGTGAGGAGATCAGTGACACCTCCCAGGAACCTTCTCCACCCAAGG
CATTTGCTGTTACCAGGTGTGGGTCCTCACACAAGCCAGGGGTCCATATGAGCCCGCAGCTTCATGGCCCAGAATCTGGACACCACAAAG
GGAAAGTGAAAGCATTGGAGGAGGATAATTTGAGTGAGTCCTCTTCTGAGAGCTTTCTCTGGAGTGATGATGAGTATGGCCAAGATGTGG
ATGTGACCACCAACCCAGATGAGGAACTTGATGGGGATGACCGCTATGACTTCGAGGTGGTCCGCTGCATCTGTGAGGTCCAGGAGGAAA
ATGACTTCATGATTCAGTGTGAAGAGTGCCAGTGCTGGCAGCATGGGGTCTGCATGGGATTACTGGAAGAAAATGTGCCCGAGAAATACA
CCTGTTATGTTTGCCAAGACCCTCCAGGTCAGAGGCCTGGCTTCAAGTACTGGTATGACAAGGAGTGGCTGAGCAGGGGACATATGCATG
GCCTGGCATTTCTAGAAGAGAACTACTCCCATCAGAATGCCAAGAAGATCGTGGCCACCCACCAGCTTCTTGGTGATGTGCAGAGAGTGA
TTGAGGTTCTGCATGGCCTGCAGCTCAAGATGAGCATCTTGCAAAGCCGGGAGCATCCTGATCTGCCGCTGTGGTGCCAGCCTTGGAAAC
AGCACTCAGGGGAGGGGAGATCTCATTTCAGAAACATCCCTGTCACTGACACCAGGAGCAAGGAGGAAGCTCCAAGCTATAGAACTTTGA
ACGGGGCAGTGGAGAAGCCCAGGCCCCTGGCCCTGCCCCTGCCGCGTTCTGTGGAGGAATCCTATATCACCAGTGAGCATTGCTACCAGA
AGCCCCGCGCCTATTACCCTGCCGTGGAGCAGAAGCTGGTGGTGGAGACGAGGGGCTCTGCCCTCGACGATGCGGTCAACCCCCTCCATG
AGAACGGCGATGATTCCCTTTCCCCGCGCCTGGGCTGGCCTCTAGACCAAGACAGGAGCAAGGGGGACAGTGACCCCAAACCCGGCTCCC
CAAAGGTGAAGGAATATGTCTCCAAAAAGGCCCTACCAGAAGAAGCCCCTGCTCGGAAGCTGCTGGACAGAGGTGGAGAGGGGCTGCTGA
GCTCCCAGCACCAGTGGCAGTTTAACCTGCTGACCCATGTGGAATCTCTTCAGGATGAAGTTACGCACAGGATGGACTCCATTGAGAAGG
AGTTGGATGTGTTGGAGAGCTGGCTGGACTACACTGGGGAACTGGAGCCCCCTGAGCCGCTGGCCAGGCTTCCGCAGCTCAAGCATTGTA
TCAAGCAGCTGCTGATGGACCTGGGCAAGGTGCAGCAGATCGCCCTCTGCTGCTCAACATGAAACTGGGCACCCAAAACTCATGGGGGCA
CAATCCTGGGGCACCTGCAGGAGGAGCTTCGCATATTTAAATAAATAAACCTAGCATGCTGAATGCACGTGACACCGACTGACTTCAGGG
ATCTGGGCCAGGAGTGTGGTGGACATTGGACAAAGAGGCCATTTTGGCTGCGGGAGGACACTCTGATCTCGAAGCCTGCCATAAAGGTAG
CAAATAGACTCTTGGGATTCCCCTCTTCTGTGCACATCGTTGAATGAAGAGAGTCTTTTTGCACAAACTTCACTTGAAATTGTGCCACTG
ATGATAAACGGAATGAGAGCCAAAAAAGTTTAGTTGGAGACAGTTGTAAATTCAATTTGGAGTTTATTTAATTGACTTTTCTATCACGTT
GGGGCACATGCCAACTCCCTGGTTTCTTCCTGGCATGGTGTTTGGGCAGCAGGCATCATTTTCCTTTTCTAGCTTCATAGGAATATTGTG
AGCTCACCATGCTGTGGAGGTTGGGAAAGAGCAGAGTCTTGGCTGCCCTGCTTTCTCCTTAGGACTCTTCACTTTTCTCACCACATCTCT
TGCATGACTTCATGGTACTGGGGACAAGTTTGTATGCCTTCACCCCAGAGCTGGCTGGGTTATGGCTTTTGTAGCAGAGCCCATACAGCC
TATGGAAGAACTAGAATCTCACTCACAGTAATAAGAATCTAGGAGGAATTCCAAACCGAAGCAGGCAGGGTCTGGAACCCAAAGGACAGC
ATTTTCTACCCACTTCTTAATATTGACAGCTTCCCCGTTCTATTTAATGTCCAAAAATGTTTCCCAAAATTTCAAACTCTTTCACTGTAA
AGATTTGTTACAAAGAATGTGGTTTGGGGAATTACCTTATTTTATATTGTTGTAAACAAACTTCAAATTCTACATGTGCGACTTTTCTCC
TTCCTGAAGGGTGTTTAGTAGTCAGCGTTTTCAGAATTGTTTTGTTACTATACTTTAACATTTTACATTTCCTGTTTGTATTATTTTGTG
AGAGCAAGGTGATCATGCTGCTTAAGGTCCAGGTACAACCTATTTGTACCTTTTGAGACAATATTTGTGTTACTTTTGCAGGTTACGGTT
CCACATGTAATTGCTATATTTTGTTTTGTTTTTCCTTACTAGGCAAAGTTAAAATGTTCCATGCTTTGAGGAGTGACCCATTTCACTACT
TTGTTTTCTTATCACTAAAGGCAAAAATCAAAGCACAGTTGTCCATTAACACTTATAAGTTAATTATGGGTTTATGAGTCTGTAATGTTA
TATGCTGCAAACATTTACTATGTAAACGTGAAGTAGCCAATAATATCTCAATAGTAGTAACAGTATCTTTAGCGACCTTTGGAATAGTTA
AGCACAGGTCATTGTGGACATGAATTCAGGCCTCTGTACTAAAATCTATTTCAGGGAATGTTCTGTCTAGTGATTTGCTCACCATTTGAT
ATATAATGAATTATAGGACAAGTATAAGCTGATCTGCTATAGCTGTCCATCAGAGAGAATACACGTGGCTATAACATCTATAACAAAACG
ACGATTCCTCTACAAGAGGCTGTTTCTCACTGCTAACGTTGGTGTTTCTGGCGTGGGAAGAAATGCACAGGCGTGCATGGCATGCACGTT
CAGACAGCTGCATTGTAAGAGTTCTGTCATGCAGTCTGAAAAGGGAAGAAACAGGATGGCTTTCTGTAGCCACACCTGTGAGGCGTGATG
ATTGTTGTATTATTAGATTACTGATTTTTCTTTTCTGAAAATACATTTGAGTTTTAATCACATCTGTGGAAGCTGTAACTTTTAAGGTAG
TCAATTTCATGTCTTGTTCAACGATGTAAGCAGAAACTGAATTGCCCTAATTTTGCCAACTGGCCATTATTGGGATTATTGTTTAAATTT
TTGGTAAAGGAAGTAATCTCCTTTCATTCATTGTGACTTTTGTTCTTAGGGAAGCAGAGAAGACTCCCCAAGTTCTTATAACCTCATTGT
GCTTCCCTAATTTAAAGCCATGTTGAGGGGCTCCATTCCCAATTCCTGGGTCAAGGTGAATTAACCCTATGTTGGAGCACTGGAAACCGT
TATTTGCAAACATTGCTGTTACCATTTAGAAATATGTGCACTATCAGCTGGGTGCAGTGGCTCACGTCTGTAATCCCAGCACTTTGGGAG
GCCGAGGCAGGTGGATCACCTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACAGGGTGAAACCCCGTCTCTACTAAAAGTACAAAAATT
AGCTGGGCGTGGTGGCGGACGCCTGTAATCTCAGCTACTTGGGAGGCTGAAGCAGGAGAGGTGCTGGAACCTGGGAGGCGGAGGTTGAAG
TGAGCCGAGATTGCGCTATTGCACTCCAGCTCGGGCGACAACTGCAAGACTCCATCTCAAAAAAATAAAAATAAAAGAAAAGAAAGAAAT
ATGTGCACTACCTAAGTTTTGTCTTTAGAAAAACTATCCACCTATAAAAAATTACCTTGACAAAAATAGTTCCGGTTTGACTAATCATTT
TGTTTCTTTAAGTGGTAAGTGTATGCAAGGTGGATCCTTGATGAGCCAACATTGCACTGTGGATACATATCTATGTTTACGCGCTATTAG
AACAGAAGGCGCTGTATATAGAAATGTTGCTTTGAAGCAATATTTGCAAAACACGCAGACTTCTGTATCTGTATTTGGAAAAAATAAAAC

>In-frame_ENST00000438120_ENST00000374012_TCGA-61-2111-01A_PTPRF_chr1_44044591_+_PHF20_chr20_34487292_length(amino acids)=821AA_start in transcript=296_stop in transcript=2761
MWLAVELEPWMAPEPAPGRTMVPLVPALVMLGLVAGAHGDSKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEV
IEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNPDPEISWFK
DFLPVDPATSNGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPANLYVRVTNTFKKTDDFGSSNAPAVDLDHKFRCKVVDCLK
FFRKAKLLHYHMKYFHGMEKSLEPEESPGKRHVQTRGPSASDKPSQETLTRKRVSASSPTTKDKEKNKEKKFKEFVRVKPKKKKKKKKKT
KPECPCSEEISDTSQEPSPPKAFAVTRCGSSHKPGVHMSPQLHGPESGHHKGKVKALEEDNLSESSSESFLWSDDEYGQDVDVTTNPDEE
LDGDDRYDFEVVRCICEVQEENDFMIQCEECQCWQHGVCMGLLEENVPEKYTCYVCQDPPGQRPGFKYWYDKEWLSRGHMHGLAFLEENY
SHQNAKKIVATHQLLGDVQRVIEVLHGLQLKMSILQSREHPDLPLWCQPWKQHSGEGRSHFRNIPVTDTRSKEEAPSYRTLNGAVEKPRP
LALPLPRSVEESYITSEHCYQKPRAYYPAVEQKLVVETRGSALDDAVNPLHENGDDSLSPRLGWPLDQDRSKGDSDPKPGSPKVKEYVSK
KALPEEAPARKLLDRGGEGLLSSQHQWQFNLLTHVESLQDEVTHRMDSIEKELDVLESWLDYTGELEPPEPLARLPQLKHCIKQLLMDLG

--------------------------------------------------------------
>In-frame_ENST00000372413_ENST00000374012_TCGA-61-2111-01A_PTPRF_chr1_44044591_+_PHF20_chr20_34487292_length(transcript)=5236nt_BP=725nt
GGTTGATTGTCCTGGGCTGTGGCTGGCTGTGGAGCTAGAGCCCTGGATGGCCCCTGAGCCAGCCCCAGGGAGGACGATGGTGCCCCTTGT
GCCTGCACTGGTGATGCTTGGTTTGGTGGCAGGCGCCCATGGTGACAGCAAACCTGTCTTCATTAAAGTCCCTGAGGACCAGACTGGGCT
GTCAGGAGGGGTAGCCTCCTTCGTGTGCCAAGCTACAGGAGAACCCAAGCCGCGCATCACATGGATGAAGAAGGGGAAGAAAGTCAGCTC
CCAGCGCTTCGAGGTCATTGAGTTTGATGATGGGGCAGGGTCAGTGCTTCGGATCCAGCCATTGCGGGTGCAGCGAGATGAAGCCATCTA
TGAGTGTACAGCTACTAACAGCCTGGGTGAGATCAACACTAGTGCCAAGCTCTCAGTGCTCGAAGAGGAACAGCTGCCCCCTGGGTTCCC
TTCCATCGACATGGGGCCTCAGCTGAAGGTGGTGGAGAAGGCACGCACAGCCACCATGCTATGTGCCGCAGGCGGAAATCCAGACCCTGA
GATTTCTTGGTTCAAGGACTTCCTTCCTGTAGACCCTGCCACGAGCAACGGCCGCATCAAGCAGCTGCGTTCAGGTGCCTTGCAGATAGA
GAGCAGTGAGGAATCCGACCAAGGCAAGTACGAGTGTGTGGCGACCAACTCGGCAGGCACACGTTACTCAGCCCCTGCGAACCTGTATGT
GCGAGTAACAAATACTTTTAAGAAAACAGATGATTTTGGGTCATCTAATGCACCAGCTGTCGACCTAGACCATAAGTTTAGATGCAAAGT
TGTGGACTGTTTAAAATTTTTCCGCAAAGCCAAACTGTTGCACTATCACATGAAGTATTTCCATGGAATGGAGAAGTCACTGGAGCCAGA
AGAGAGCCCGGGAAAGAGGCATGTCCAAACCAGGGGCCCTTCAGCTTCAGACAAGCCCAGCCAGGAGACCCTGACCAGGAAGCGGGTCTC
TGCCAGTTCCCCAACTACAAAAGACAAGGAAAAGAATAAAGAGAAGAAATTCAAGGAGTTTGTGAGAGTGAAGCCAAAGAAGAAAAAGAA
AAAGAAAAAGAAAACCAAACCTGAATGCCCCTGCAGTGAGGAGATCAGTGACACCTCCCAGGAACCTTCTCCACCCAAGGCATTTGCTGT
TACCAGGTGTGGGTCCTCACACAAGCCAGGGGTCCATATGAGCCCGCAGCTTCATGGCCCAGAATCTGGACACCACAAAGGGAAAGTGAA
AGCATTGGAGGAGGATAATTTGAGTGAGTCCTCTTCTGAGAGCTTTCTCTGGAGTGATGATGAGTATGGCCAAGATGTGGATGTGACCAC
CAACCCAGATGAGGAACTTGATGGGGATGACCGCTATGACTTCGAGGTGGTCCGCTGCATCTGTGAGGTCCAGGAGGAAAATGACTTCAT
GATTCAGTGTGAAGAGTGCCAGTGCTGGCAGCATGGGGTCTGCATGGGATTACTGGAAGAAAATGTGCCCGAGAAATACACCTGTTATGT
TTGCCAAGACCCTCCAGGTCAGAGGCCTGGCTTCAAGTACTGGTATGACAAGGAGTGGCTGAGCAGGGGACATATGCATGGCCTGGCATT
TCTAGAAGAGAACTACTCCCATCAGAATGCCAAGAAGATCGTGGCCACCCACCAGCTTCTTGGTGATGTGCAGAGAGTGATTGAGGTTCT
GCATGGCCTGCAGCTCAAGATGAGCATCTTGCAAAGCCGGGAGCATCCTGATCTGCCGCTGTGGTGCCAGCCTTGGAAACAGCACTCAGG
GGAGGGGAGATCTCATTTCAGAAACATCCCTGTCACTGACACCAGGAGCAAGGAGGAAGCTCCAAGCTATAGAACTTTGAACGGGGCAGT
GGAGAAGCCCAGGCCCCTGGCCCTGCCCCTGCCGCGTTCTGTGGAGGAATCCTATATCACCAGTGAGCATTGCTACCAGAAGCCCCGCGC
CTATTACCCTGCCGTGGAGCAGAAGCTGGTGGTGGAGACGAGGGGCTCTGCCCTCGACGATGCGGTCAACCCCCTCCATGAGAACGGCGA
TGATTCCCTTTCCCCGCGCCTGGGCTGGCCTCTAGACCAAGACAGGAGCAAGGGGGACAGTGACCCCAAACCCGGCTCCCCAAAGGTGAA
GGAATATGTCTCCAAAAAGGCCCTACCAGAAGAAGCCCCTGCTCGGAAGCTGCTGGACAGAGGTGGAGAGGGGCTGCTGAGCTCCCAGCA
CCAGTGGCAGTTTAACCTGCTGACCCATGTGGAATCTCTTCAGGATGAAGTTACGCACAGGATGGACTCCATTGAGAAGGAGTTGGATGT
GTTGGAGAGCTGGCTGGACTACACTGGGGAACTGGAGCCCCCTGAGCCGCTGGCCAGGCTTCCGCAGCTCAAGCATTGTATCAAGCAGCT
GCTGATGGACCTGGGCAAGGTGCAGCAGATCGCCCTCTGCTGCTCAACATGAAACTGGGCACCCAAAACTCATGGGGGCACAATCCTGGG
GCACCTGCAGGAGGAGCTTCGCATATTTAAATAAATAAACCTAGCATGCTGAATGCACGTGACACCGACTGACTTCAGGGATCTGGGCCA
GGAGTGTGGTGGACATTGGACAAAGAGGCCATTTTGGCTGCGGGAGGACACTCTGATCTCGAAGCCTGCCATAAAGGTAGCAAATAGACT
CTTGGGATTCCCCTCTTCTGTGCACATCGTTGAATGAAGAGAGTCTTTTTGCACAAACTTCACTTGAAATTGTGCCACTGATGATAAACG
GAATGAGAGCCAAAAAAGTTTAGTTGGAGACAGTTGTAAATTCAATTTGGAGTTTATTTAATTGACTTTTCTATCACGTTGGGGCACATG
CCAACTCCCTGGTTTCTTCCTGGCATGGTGTTTGGGCAGCAGGCATCATTTTCCTTTTCTAGCTTCATAGGAATATTGTGAGCTCACCAT
GCTGTGGAGGTTGGGAAAGAGCAGAGTCTTGGCTGCCCTGCTTTCTCCTTAGGACTCTTCACTTTTCTCACCACATCTCTTGCATGACTT
CATGGTACTGGGGACAAGTTTGTATGCCTTCACCCCAGAGCTGGCTGGGTTATGGCTTTTGTAGCAGAGCCCATACAGCCTATGGAAGAA
CTAGAATCTCACTCACAGTAATAAGAATCTAGGAGGAATTCCAAACCGAAGCAGGCAGGGTCTGGAACCCAAAGGACAGCATTTTCTACC
CACTTCTTAATATTGACAGCTTCCCCGTTCTATTTAATGTCCAAAAATGTTTCCCAAAATTTCAAACTCTTTCACTGTAAAGATTTGTTA
CAAAGAATGTGGTTTGGGGAATTACCTTATTTTATATTGTTGTAAACAAACTTCAAATTCTACATGTGCGACTTTTCTCCTTCCTGAAGG
GTGTTTAGTAGTCAGCGTTTTCAGAATTGTTTTGTTACTATACTTTAACATTTTACATTTCCTGTTTGTATTATTTTGTGAGAGCAAGGT
GATCATGCTGCTTAAGGTCCAGGTACAACCTATTTGTACCTTTTGAGACAATATTTGTGTTACTTTTGCAGGTTACGGTTCCACATGTAA
TTGCTATATTTTGTTTTGTTTTTCCTTACTAGGCAAAGTTAAAATGTTCCATGCTTTGAGGAGTGACCCATTTCACTACTTTGTTTTCTT
ATCACTAAAGGCAAAAATCAAAGCACAGTTGTCCATTAACACTTATAAGTTAATTATGGGTTTATGAGTCTGTAATGTTATATGCTGCAA
ACATTTACTATGTAAACGTGAAGTAGCCAATAATATCTCAATAGTAGTAACAGTATCTTTAGCGACCTTTGGAATAGTTAAGCACAGGTC
ATTGTGGACATGAATTCAGGCCTCTGTACTAAAATCTATTTCAGGGAATGTTCTGTCTAGTGATTTGCTCACCATTTGATATATAATGAA
TTATAGGACAAGTATAAGCTGATCTGCTATAGCTGTCCATCAGAGAGAATACACGTGGCTATAACATCTATAACAAAACGACGATTCCTC
TACAAGAGGCTGTTTCTCACTGCTAACGTTGGTGTTTCTGGCGTGGGAAGAAATGCACAGGCGTGCATGGCATGCACGTTCAGACAGCTG
CATTGTAAGAGTTCTGTCATGCAGTCTGAAAAGGGAAGAAACAGGATGGCTTTCTGTAGCCACACCTGTGAGGCGTGATGATTGTTGTAT
TATTAGATTACTGATTTTTCTTTTCTGAAAATACATTTGAGTTTTAATCACATCTGTGGAAGCTGTAACTTTTAAGGTAGTCAATTTCAT
GTCTTGTTCAACGATGTAAGCAGAAACTGAATTGCCCTAATTTTGCCAACTGGCCATTATTGGGATTATTGTTTAAATTTTTGGTAAAGG
AAGTAATCTCCTTTCATTCATTGTGACTTTTGTTCTTAGGGAAGCAGAGAAGACTCCCCAAGTTCTTATAACCTCATTGTGCTTCCCTAA
TTTAAAGCCATGTTGAGGGGCTCCATTCCCAATTCCTGGGTCAAGGTGAATTAACCCTATGTTGGAGCACTGGAAACCGTTATTTGCAAA
CATTGCTGTTACCATTTAGAAATATGTGCACTATCAGCTGGGTGCAGTGGCTCACGTCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAG
GTGGATCACCTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACAGGGTGAAACCCCGTCTCTACTAAAAGTACAAAAATTAGCTGGGCGT
GGTGGCGGACGCCTGTAATCTCAGCTACTTGGGAGGCTGAAGCAGGAGAGGTGCTGGAACCTGGGAGGCGGAGGTTGAAGTGAGCCGAGA
TTGCGCTATTGCACTCCAGCTCGGGCGACAACTGCAAGACTCCATCTCAAAAAAATAAAAATAAAAGAAAAGAAAGAAATATGTGCACTA
CCTAAGTTTTGTCTTTAGAAAAACTATCCACCTATAAAAAATTACCTTGACAAAAATAGTTCCGGTTTGACTAATCATTTTGTTTCTTTA
AGTGGTAAGTGTATGCAAGGTGGATCCTTGATGAGCCAACATTGCACTGTGGATACATATCTATGTTTACGCGCTATTAGAACAGAAGGC
GCTGTATATAGAAATGTTGCTTTGAAGCAATATTTGCAAAACACGCAGACTTCTGTATCTGTATTTGGAAAAAATAAAACAGGTTCTTGT

>In-frame_ENST00000372413_ENST00000374012_TCGA-61-2111-01A_PTPRF_chr1_44044591_+_PHF20_chr20_34487292_length(amino acids)=821AA_start in transcript=16_stop in transcript=2481
MWLAVELEPWMAPEPAPGRTMVPLVPALVMLGLVAGAHGDSKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEV
IEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNPDPEISWFK
DFLPVDPATSNGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPANLYVRVTNTFKKTDDFGSSNAPAVDLDHKFRCKVVDCLK
FFRKAKLLHYHMKYFHGMEKSLEPEESPGKRHVQTRGPSASDKPSQETLTRKRVSASSPTTKDKEKNKEKKFKEFVRVKPKKKKKKKKKT
KPECPCSEEISDTSQEPSPPKAFAVTRCGSSHKPGVHMSPQLHGPESGHHKGKVKALEEDNLSESSSESFLWSDDEYGQDVDVTTNPDEE
LDGDDRYDFEVVRCICEVQEENDFMIQCEECQCWQHGVCMGLLEENVPEKYTCYVCQDPPGQRPGFKYWYDKEWLSRGHMHGLAFLEENY
SHQNAKKIVATHQLLGDVQRVIEVLHGLQLKMSILQSREHPDLPLWCQPWKQHSGEGRSHFRNIPVTDTRSKEEAPSYRTLNGAVEKPRP
LALPLPRSVEESYITSEHCYQKPRAYYPAVEQKLVVETRGSALDDAVNPLHENGDDSLSPRLGWPLDQDRSKGDSDPKPGSPKVKEYVSK
KALPEEAPARKLLDRGGEGLLSSQHQWQFNLLTHVESLQDEVTHRMDSIEKELDVLESWLDYTGELEPPEPLARLPQLKHCIKQLLMDLG

--------------------------------------------------------------
>In-frame_ENST00000372414_ENST00000374012_TCGA-61-2111-01A_PTPRF_chr1_44044591_+_PHF20_chr20_34487292_length(transcript)=5236nt_BP=725nt
GGTTGATTGTCCTGGGCTGTGGCTGGCTGTGGAGCTAGAGCCCTGGATGGCCCCTGAGCCAGCCCCAGGGAGGACGATGGTGCCCCTTGT
GCCTGCACTGGTGATGCTTGGTTTGGTGGCAGGCGCCCATGGTGACAGCAAACCTGTCTTCATTAAAGTCCCTGAGGACCAGACTGGGCT
GTCAGGAGGGGTAGCCTCCTTCGTGTGCCAAGCTACAGGAGAACCCAAGCCGCGCATCACATGGATGAAGAAGGGGAAGAAAGTCAGCTC
CCAGCGCTTCGAGGTCATTGAGTTTGATGATGGGGCAGGGTCAGTGCTTCGGATCCAGCCATTGCGGGTGCAGCGAGATGAAGCCATCTA
TGAGTGTACAGCTACTAACAGCCTGGGTGAGATCAACACTAGTGCCAAGCTCTCAGTGCTCGAAGAGGAACAGCTGCCCCCTGGGTTCCC
TTCCATCGACATGGGGCCTCAGCTGAAGGTGGTGGAGAAGGCACGCACAGCCACCATGCTATGTGCCGCAGGCGGAAATCCAGACCCTGA
GATTTCTTGGTTCAAGGACTTCCTTCCTGTAGACCCTGCCACGAGCAACGGCCGCATCAAGCAGCTGCGTTCAGGTGCCTTGCAGATAGA
GAGCAGTGAGGAATCCGACCAAGGCAAGTACGAGTGTGTGGCGACCAACTCGGCAGGCACACGTTACTCAGCCCCTGCGAACCTGTATGT
GCGAGTAACAAATACTTTTAAGAAAACAGATGATTTTGGGTCATCTAATGCACCAGCTGTCGACCTAGACCATAAGTTTAGATGCAAAGT
TGTGGACTGTTTAAAATTTTTCCGCAAAGCCAAACTGTTGCACTATCACATGAAGTATTTCCATGGAATGGAGAAGTCACTGGAGCCAGA
AGAGAGCCCGGGAAAGAGGCATGTCCAAACCAGGGGCCCTTCAGCTTCAGACAAGCCCAGCCAGGAGACCCTGACCAGGAAGCGGGTCTC
TGCCAGTTCCCCAACTACAAAAGACAAGGAAAAGAATAAAGAGAAGAAATTCAAGGAGTTTGTGAGAGTGAAGCCAAAGAAGAAAAAGAA
AAAGAAAAAGAAAACCAAACCTGAATGCCCCTGCAGTGAGGAGATCAGTGACACCTCCCAGGAACCTTCTCCACCCAAGGCATTTGCTGT
TACCAGGTGTGGGTCCTCACACAAGCCAGGGGTCCATATGAGCCCGCAGCTTCATGGCCCAGAATCTGGACACCACAAAGGGAAAGTGAA
AGCATTGGAGGAGGATAATTTGAGTGAGTCCTCTTCTGAGAGCTTTCTCTGGAGTGATGATGAGTATGGCCAAGATGTGGATGTGACCAC
CAACCCAGATGAGGAACTTGATGGGGATGACCGCTATGACTTCGAGGTGGTCCGCTGCATCTGTGAGGTCCAGGAGGAAAATGACTTCAT
GATTCAGTGTGAAGAGTGCCAGTGCTGGCAGCATGGGGTCTGCATGGGATTACTGGAAGAAAATGTGCCCGAGAAATACACCTGTTATGT
TTGCCAAGACCCTCCAGGTCAGAGGCCTGGCTTCAAGTACTGGTATGACAAGGAGTGGCTGAGCAGGGGACATATGCATGGCCTGGCATT
TCTAGAAGAGAACTACTCCCATCAGAATGCCAAGAAGATCGTGGCCACCCACCAGCTTCTTGGTGATGTGCAGAGAGTGATTGAGGTTCT
GCATGGCCTGCAGCTCAAGATGAGCATCTTGCAAAGCCGGGAGCATCCTGATCTGCCGCTGTGGTGCCAGCCTTGGAAACAGCACTCAGG
GGAGGGGAGATCTCATTTCAGAAACATCCCTGTCACTGACACCAGGAGCAAGGAGGAAGCTCCAAGCTATAGAACTTTGAACGGGGCAGT
GGAGAAGCCCAGGCCCCTGGCCCTGCCCCTGCCGCGTTCTGTGGAGGAATCCTATATCACCAGTGAGCATTGCTACCAGAAGCCCCGCGC
CTATTACCCTGCCGTGGAGCAGAAGCTGGTGGTGGAGACGAGGGGCTCTGCCCTCGACGATGCGGTCAACCCCCTCCATGAGAACGGCGA
TGATTCCCTTTCCCCGCGCCTGGGCTGGCCTCTAGACCAAGACAGGAGCAAGGGGGACAGTGACCCCAAACCCGGCTCCCCAAAGGTGAA
GGAATATGTCTCCAAAAAGGCCCTACCAGAAGAAGCCCCTGCTCGGAAGCTGCTGGACAGAGGTGGAGAGGGGCTGCTGAGCTCCCAGCA
CCAGTGGCAGTTTAACCTGCTGACCCATGTGGAATCTCTTCAGGATGAAGTTACGCACAGGATGGACTCCATTGAGAAGGAGTTGGATGT
GTTGGAGAGCTGGCTGGACTACACTGGGGAACTGGAGCCCCCTGAGCCGCTGGCCAGGCTTCCGCAGCTCAAGCATTGTATCAAGCAGCT
GCTGATGGACCTGGGCAAGGTGCAGCAGATCGCCCTCTGCTGCTCAACATGAAACTGGGCACCCAAAACTCATGGGGGCACAATCCTGGG
GCACCTGCAGGAGGAGCTTCGCATATTTAAATAAATAAACCTAGCATGCTGAATGCACGTGACACCGACTGACTTCAGGGATCTGGGCCA
GGAGTGTGGTGGACATTGGACAAAGAGGCCATTTTGGCTGCGGGAGGACACTCTGATCTCGAAGCCTGCCATAAAGGTAGCAAATAGACT
CTTGGGATTCCCCTCTTCTGTGCACATCGTTGAATGAAGAGAGTCTTTTTGCACAAACTTCACTTGAAATTGTGCCACTGATGATAAACG
GAATGAGAGCCAAAAAAGTTTAGTTGGAGACAGTTGTAAATTCAATTTGGAGTTTATTTAATTGACTTTTCTATCACGTTGGGGCACATG
CCAACTCCCTGGTTTCTTCCTGGCATGGTGTTTGGGCAGCAGGCATCATTTTCCTTTTCTAGCTTCATAGGAATATTGTGAGCTCACCAT
GCTGTGGAGGTTGGGAAAGAGCAGAGTCTTGGCTGCCCTGCTTTCTCCTTAGGACTCTTCACTTTTCTCACCACATCTCTTGCATGACTT
CATGGTACTGGGGACAAGTTTGTATGCCTTCACCCCAGAGCTGGCTGGGTTATGGCTTTTGTAGCAGAGCCCATACAGCCTATGGAAGAA
CTAGAATCTCACTCACAGTAATAAGAATCTAGGAGGAATTCCAAACCGAAGCAGGCAGGGTCTGGAACCCAAAGGACAGCATTTTCTACC
CACTTCTTAATATTGACAGCTTCCCCGTTCTATTTAATGTCCAAAAATGTTTCCCAAAATTTCAAACTCTTTCACTGTAAAGATTTGTTA
CAAAGAATGTGGTTTGGGGAATTACCTTATTTTATATTGTTGTAAACAAACTTCAAATTCTACATGTGCGACTTTTCTCCTTCCTGAAGG
GTGTTTAGTAGTCAGCGTTTTCAGAATTGTTTTGTTACTATACTTTAACATTTTACATTTCCTGTTTGTATTATTTTGTGAGAGCAAGGT
GATCATGCTGCTTAAGGTCCAGGTACAACCTATTTGTACCTTTTGAGACAATATTTGTGTTACTTTTGCAGGTTACGGTTCCACATGTAA
TTGCTATATTTTGTTTTGTTTTTCCTTACTAGGCAAAGTTAAAATGTTCCATGCTTTGAGGAGTGACCCATTTCACTACTTTGTTTTCTT
ATCACTAAAGGCAAAAATCAAAGCACAGTTGTCCATTAACACTTATAAGTTAATTATGGGTTTATGAGTCTGTAATGTTATATGCTGCAA
ACATTTACTATGTAAACGTGAAGTAGCCAATAATATCTCAATAGTAGTAACAGTATCTTTAGCGACCTTTGGAATAGTTAAGCACAGGTC
ATTGTGGACATGAATTCAGGCCTCTGTACTAAAATCTATTTCAGGGAATGTTCTGTCTAGTGATTTGCTCACCATTTGATATATAATGAA
TTATAGGACAAGTATAAGCTGATCTGCTATAGCTGTCCATCAGAGAGAATACACGTGGCTATAACATCTATAACAAAACGACGATTCCTC
TACAAGAGGCTGTTTCTCACTGCTAACGTTGGTGTTTCTGGCGTGGGAAGAAATGCACAGGCGTGCATGGCATGCACGTTCAGACAGCTG
CATTGTAAGAGTTCTGTCATGCAGTCTGAAAAGGGAAGAAACAGGATGGCTTTCTGTAGCCACACCTGTGAGGCGTGATGATTGTTGTAT
TATTAGATTACTGATTTTTCTTTTCTGAAAATACATTTGAGTTTTAATCACATCTGTGGAAGCTGTAACTTTTAAGGTAGTCAATTTCAT
GTCTTGTTCAACGATGTAAGCAGAAACTGAATTGCCCTAATTTTGCCAACTGGCCATTATTGGGATTATTGTTTAAATTTTTGGTAAAGG
AAGTAATCTCCTTTCATTCATTGTGACTTTTGTTCTTAGGGAAGCAGAGAAGACTCCCCAAGTTCTTATAACCTCATTGTGCTTCCCTAA
TTTAAAGCCATGTTGAGGGGCTCCATTCCCAATTCCTGGGTCAAGGTGAATTAACCCTATGTTGGAGCACTGGAAACCGTTATTTGCAAA
CATTGCTGTTACCATTTAGAAATATGTGCACTATCAGCTGGGTGCAGTGGCTCACGTCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAG
GTGGATCACCTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACAGGGTGAAACCCCGTCTCTACTAAAAGTACAAAAATTAGCTGGGCGT
GGTGGCGGACGCCTGTAATCTCAGCTACTTGGGAGGCTGAAGCAGGAGAGGTGCTGGAACCTGGGAGGCGGAGGTTGAAGTGAGCCGAGA
TTGCGCTATTGCACTCCAGCTCGGGCGACAACTGCAAGACTCCATCTCAAAAAAATAAAAATAAAAGAAAAGAAAGAAATATGTGCACTA
CCTAAGTTTTGTCTTTAGAAAAACTATCCACCTATAAAAAATTACCTTGACAAAAATAGTTCCGGTTTGACTAATCATTTTGTTTCTTTA
AGTGGTAAGTGTATGCAAGGTGGATCCTTGATGAGCCAACATTGCACTGTGGATACATATCTATGTTTACGCGCTATTAGAACAGAAGGC
GCTGTATATAGAAATGTTGCTTTGAAGCAATATTTGCAAAACACGCAGACTTCTGTATCTGTATTTGGAAAAAATAAAACAGGTTCTTGT

>In-frame_ENST00000372414_ENST00000374012_TCGA-61-2111-01A_PTPRF_chr1_44044591_+_PHF20_chr20_34487292_length(amino acids)=821AA_start in transcript=16_stop in transcript=2481
MWLAVELEPWMAPEPAPGRTMVPLVPALVMLGLVAGAHGDSKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEV
IEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNPDPEISWFK
DFLPVDPATSNGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPANLYVRVTNTFKKTDDFGSSNAPAVDLDHKFRCKVVDCLK
FFRKAKLLHYHMKYFHGMEKSLEPEESPGKRHVQTRGPSASDKPSQETLTRKRVSASSPTTKDKEKNKEKKFKEFVRVKPKKKKKKKKKT
KPECPCSEEISDTSQEPSPPKAFAVTRCGSSHKPGVHMSPQLHGPESGHHKGKVKALEEDNLSESSSESFLWSDDEYGQDVDVTTNPDEE
LDGDDRYDFEVVRCICEVQEENDFMIQCEECQCWQHGVCMGLLEENVPEKYTCYVCQDPPGQRPGFKYWYDKEWLSRGHMHGLAFLEENY
SHQNAKKIVATHQLLGDVQRVIEVLHGLQLKMSILQSREHPDLPLWCQPWKQHSGEGRSHFRNIPVTDTRSKEEAPSYRTLNGAVEKPRP
LALPLPRSVEESYITSEHCYQKPRAYYPAVEQKLVVETRGSALDDAVNPLHENGDDSLSPRLGWPLDQDRSKGDSDPKPGSPKVKEYVSK
KALPEEAPARKLLDRGGEGLLSSQHQWQFNLLTHVESLQDEVTHRMDSIEKELDVLESWLDYTGELEPPEPLARLPQLKHCIKQLLMDLG

--------------------------------------------------------------

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Fusion Gene PPI Analysis for PTPRF-PHF20


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for PTPRF-PHF20


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for PTPRF-PHF20


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgenePTPRFC0024623Malignant neoplasm of stomach1CTD_human
HgenePTPRFC0038356Stomach Neoplasms1CTD_human
HgenePTPRFC0175755Congenital absent nipple1GENOMICS_ENGLAND
HgenePTPRFC0235874Disease Exacerbation1CTD_human
HgenePTPRFC0345967Malignant mesothelioma1CTD_human
HgenePTPRFC0432357Congenital absence of breast with absent nipple1ORPHANET
HgenePTPRFC1708349Hereditary Diffuse Gastric Cancer1CTD_human