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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:RALGAPA1-VWA5A (FusionGDB2 ID:71461)

Fusion Gene Summary for RALGAPA1-VWA5A

check button Fusion gene summary
Fusion gene informationFusion gene name: RALGAPA1-VWA5A
Fusion gene ID: 71461
HgeneTgene
Gene symbol

RALGAPA1

VWA5A

Gene ID

253959

4013

Gene nameRal GTPase activating protein catalytic subunit alpha 1von Willebrand factor A domain containing 5A
SynonymsGARNL1|GRIPE|NEDHRIT|RalGAPalpha1|TULIP1|p240BCSC-1|BCSC1|LOH11CR2A
Cytomap

14q13.2

11q24.2

Type of geneprotein-codingprotein-coding
Descriptionral GTPase-activating protein subunit alpha-1GAP-related interacting protein to E12GTPase activating Rap/RanGAP domain-like 1Ral GTPase activating protein catalytic alpha subunit 1Ral GTPase activating protein, alpha subunit 1 (catalytic)tuberin-likevon Willebrand factor A domain-containing protein 5Abreast cancer suppressor candidate 1loss of heterozygosity 11 chromosomal region 2 gene A proteinloss of heterozygosity, 11, chromosomal region 2, gene Aortholog of mouse AW551984
Modification date2020031420200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000389698, ENST00000307138, 
ENST00000258840, ENST00000382366, 
ENST00000554704, 		ENST00000456829, 
ENST00000361352, ENST00000449321, 
ENST00000392748, ENST00000360334, 
ENST00000392744, 
Fusion gene scores* DoF score5 X 5 X 3=753 X 4 X 2=24
# samples 63
** MAII scorelog2(6/75*10)=-0.321928094887362
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(3/24*10)=0.321928094887362
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: RALGAPA1 [Title/Abstract] AND VWA5A [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointRALGAPA1(36231915)-VWA5A(124007280), # samples:1
Anticipated loss of major functional domain due to fusion event.RALGAPA1-VWA5A seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
RALGAPA1-VWA5A seems lost the major protein functional domain in Tgene partner, which is a tumor suppressor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across RALGAPA1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across VWA5A (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-IN-8462RALGAPA1chr14

36231915

-VWA5Achr11

124007280

+


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Fusion Gene ORF analysis for RALGAPA1-VWA5A

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000389698ENST00000456829RALGAPA1chr14

36231915

-VWA5Achr11

124007280

+
5CDS-intronENST00000389698ENST00000361352RALGAPA1chr14

36231915

-VWA5Achr11

124007280

+
5CDS-intronENST00000389698ENST00000449321RALGAPA1chr14

36231915

-VWA5Achr11

124007280

+
5CDS-intronENST00000389698ENST00000392748RALGAPA1chr14

36231915

-VWA5Achr11

124007280

+
5CDS-intronENST00000389698ENST00000360334RALGAPA1chr14

36231915

-VWA5Achr11

124007280

+
5CDS-intronENST00000389698ENST00000392744RALGAPA1chr14

36231915

-VWA5Achr11

124007280

+
In-frameENST00000307138ENST00000456829RALGAPA1chr14

36231915

-VWA5Achr11

124007280

+
5CDS-intronENST00000307138ENST00000361352RALGAPA1chr14

36231915

-VWA5Achr11

124007280

+
5CDS-intronENST00000307138ENST00000449321RALGAPA1chr14

36231915

-VWA5Achr11

124007280

+
5CDS-intronENST00000307138ENST00000392748RALGAPA1chr14

36231915

-VWA5Achr11

124007280

+
5CDS-intronENST00000307138ENST00000360334RALGAPA1chr14

36231915

-VWA5Achr11

124007280

+
5CDS-intronENST00000307138ENST00000392744RALGAPA1chr14

36231915

-VWA5Achr11

124007280

+
Frame-shiftENST00000258840ENST00000456829RALGAPA1chr14

36231915

-VWA5Achr11

124007280

+
5CDS-intronENST00000258840ENST00000361352RALGAPA1chr14

36231915

-VWA5Achr11

124007280

+
5CDS-intronENST00000258840ENST00000449321RALGAPA1chr14

36231915

-VWA5Achr11

124007280

+
5CDS-intronENST00000258840ENST00000392748RALGAPA1chr14

36231915

-VWA5Achr11

124007280

+
5CDS-intronENST00000258840ENST00000360334RALGAPA1chr14

36231915

-VWA5Achr11

124007280

+
5CDS-intronENST00000258840ENST00000392744RALGAPA1chr14

36231915

-VWA5Achr11

124007280

+
Frame-shiftENST00000382366ENST00000456829RALGAPA1chr14

36231915

-VWA5Achr11

124007280

+
5CDS-intronENST00000382366ENST00000361352RALGAPA1chr14

36231915

-VWA5Achr11

124007280

+
5CDS-intronENST00000382366ENST00000449321RALGAPA1chr14

36231915

-VWA5Achr11

124007280

+
5CDS-intronENST00000382366ENST00000392748RALGAPA1chr14

36231915

-VWA5Achr11

124007280

+
5CDS-intronENST00000382366ENST00000360334RALGAPA1chr14

36231915

-VWA5Achr11

124007280

+
5CDS-intronENST00000382366ENST00000392744RALGAPA1chr14

36231915

-VWA5Achr11

124007280

+
intron-3CDSENST00000554704ENST00000456829RALGAPA1chr14

36231915

-VWA5Achr11

124007280

+
intron-intronENST00000554704ENST00000361352RALGAPA1chr14

36231915

-VWA5Achr11

124007280

+
intron-intronENST00000554704ENST00000449321RALGAPA1chr14

36231915

-VWA5Achr11

124007280

+
intron-intronENST00000554704ENST00000392748RALGAPA1chr14

36231915

-VWA5Achr11

124007280

+
intron-intronENST00000554704ENST00000360334RALGAPA1chr14

36231915

-VWA5Achr11

124007280

+
intron-intronENST00000554704ENST00000392744RALGAPA1chr14

36231915

-VWA5Achr11

124007280

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000307138RALGAPA1chr1436231915-ENST00000456829VWA5Achr11124007280+34518384241674416

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000307138ENST00000456829RALGAPA1chr1436231915-VWA5Achr11124007280+0.001715910.99828404

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Fusion Genomic Features for RALGAPA1-VWA5A


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
RALGAPA1chr1436231915-VWA5Achr11124007280+0.124820620.87517935
RALGAPA1chr1436231915-VWA5Achr11124007280+0.124820620.87517935

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for RALGAPA1-VWA5A


check button Go to

FGviewer for the breakpoints of chr14:36231915-chr11:124007280

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneVWA5Achr14:36231915chr11:124007280ENST000003603340141_1310777.0DomainVIT
TgeneVWA5Achr14:36231915chr11:124007280ENST00000360334014281_4620777.0DomainVWFA
TgeneVWA5Achr14:36231915chr11:124007280ENST000003613520101_1310416.0DomainVIT
TgeneVWA5Achr14:36231915chr11:124007280ENST00000361352010281_4620416.0DomainVWFA
TgeneVWA5Achr14:36231915chr11:124007280ENST000004493210111_1310416.0DomainVIT
TgeneVWA5Achr14:36231915chr11:124007280ENST00000449321011281_4620416.0DomainVWFA

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneRALGAPA1chr14:36231915chr11:124007280ENST00000258840-5421716_1744123.02337.6666666666665Coiled coilOntology_term=ECO:0000255
HgeneRALGAPA1chr14:36231915chr11:124007280ENST00000307138-5401716_1744123.02084.0Coiled coilOntology_term=ECO:0000255
HgeneRALGAPA1chr14:36231915chr11:124007280ENST00000389698-5411716_1744123.02291.0Coiled coilOntology_term=ECO:0000255
HgeneRALGAPA1chr14:36231915chr11:124007280ENST00000258840-542379_382123.02337.6666666666665Compositional biasNote=Poly-Ser
HgeneRALGAPA1chr14:36231915chr11:124007280ENST00000307138-540379_382123.02084.0Compositional biasNote=Poly-Ser
HgeneRALGAPA1chr14:36231915chr11:124007280ENST00000389698-541379_382123.02291.0Compositional biasNote=Poly-Ser
HgeneRALGAPA1chr14:36231915chr11:124007280ENST00000258840-5421796_2004123.02337.6666666666665DomainRap-GAP
HgeneRALGAPA1chr14:36231915chr11:124007280ENST00000307138-5401796_2004123.02084.0DomainRap-GAP
HgeneRALGAPA1chr14:36231915chr11:124007280ENST00000389698-5411796_2004123.02291.0DomainRap-GAP
HgeneRALGAPA1chr14:36231915chr11:124007280ENST00000258840-5421327_2035123.02337.6666666666665RegionMinimal domain that binds to TCF3/E12
HgeneRALGAPA1chr14:36231915chr11:124007280ENST00000307138-5401327_2035123.02084.0RegionMinimal domain that binds to TCF3/E12
HgeneRALGAPA1chr14:36231915chr11:124007280ENST00000389698-5411327_2035123.02291.0RegionMinimal domain that binds to TCF3/E12
TgeneVWA5Achr14:36231915chr11:124007280ENST0000039274811181_131508.0787.0DomainVIT
TgeneVWA5Achr14:36231915chr11:124007280ENST000003927481118281_462508.0787.0DomainVWFA
TgeneVWA5Achr14:36231915chr11:124007280ENST0000045682912191_131508.0787.0DomainVIT
TgeneVWA5Achr14:36231915chr11:124007280ENST000004568291219281_462508.0787.0DomainVWFA


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Fusion Gene Sequence for RALGAPA1-VWA5A


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000307138_ENST00000456829_TCGA-IN-8462_RALGAPA1_chr14_36231915_-_VWA5A_chr11_124007280_length(transcript)=3451nt_BP=838nt
ATCACTACCACACTCGTCTCCGTTTCGGCCTCTGCAGGGTGTAAGCTGCTAAAGAAGCTTCAACCTTAAGGGGGCCTCAGGGAGAGAGTT
GTGCTCCTGCCGCCGAGAGCTCCACCTTCGTGGCTCTGGGTCCGGGGCCCCGGCCTGTGGCGGCGAGCGGCGGCCGCTGGAGACGAGCGG
CGGCGGCAGGCGGCCAGCCCGGGTCTGCCTCGCTCCGTGCAGGGCCGGGAGAGGGATCCGCCATATTGGAGCTGGGGCCGAAGGTGCCTT
GGAGCCGCGGCGCGAGGCGGGTGGAGGTGGCGGCCCTGGCCTGGATCGGGAAGGAGTCGGCTCTGCCCTGGCCCGCAAGGCTGGGGAGCT
AATGAGCCTCTCTGGCTAGTCTCCTCCCCGTCCACTCCCTCCACTTTCTGCCGCCGGGACCCGGCTGGGAGCCGGCTGTGGCAGTGGCAG
TGGCAGTGGCAGCGACAGGATGTTCTCCAAGAAGCCGCACGGGGACGTGAAGAAGTCCACCCAGAAGGTGCTAGACACCAAGAAGGACGC
ACTGACTCGCCTCAAGCACCTGCGCATCGTCATCGAGAATGCAGAATCTATTGATCTTAAACAGTTTTTCGACCAACATTTTTCACATAT
ATACTATGTGTTCTTTGAAAATTTTGTGACTATTGAAGCTAGTCTTAAACAGAAAGGTCACAAGTCTCAAAGAGAGGAATTGGATGCTAT
ACTTTTTATTTTTGAGAAAATTTTACAACTTCTTCCAGAAAGAATTCATCAGCGATGGCAGTTTCATAGTATTGGATTGATTTTAAAGAA
GCTACTTCACACAGGAAACTCCTTAAAGGCAGCAGAGACAACAGGAGAAGTATGCCTCAAATATACACTCCAGGGCAAGACTTTTGAGGA
TAAGGTGACATTTCCTCTACAACCCAAGCCTGATGTCAACCTCACCATTCACCGCCTTGCTGCCAAGTCCTTGCTCCAGACCAAGGACAT
GGGCCTCAGGGAGACTCCAGCAAGTGATAAAAAAGATGCATTGAACCTTAGCCTTGAGTCTGGTGTCATAAGCTCCTTCACAGCTTTCAT
TGCTATCAATAAGGAGCTCAACAAGCCGGTTCAGGGGCCTCTGGCTCATAGGGACGTCCCAAGGCCAATTCTGTTGGGTGCTTCTGCCCC
ATTGAAGATAAAATGCCAATCAGGTTTTCGAAAGGCCTTACACTCTGACCGTCCTCCTTCTGCATCTCAGCCCAGAGGGGAACTTATGTG
TTATAAGGCCAAGACATTCCAGATGGACGATTACAGTCTCTGTGGGTTGATAAGTCACAAGGACCAGCACAGTCCAGGCTTTGGAGAGAA
TCACCTTGTGCAGCTGATTTACCACCAAAATGCAAATGGTTCCTGGGATCTGAATGAAGATCTAGCCAAGATCCTAGGTATGAGTTTGGA
AGAAATAATGGCTGCACAGCCTGCCGAGCTTGTGGATTCCTCAGGCTGGGCCACCATCCTGGCCGTGATCTGGCTGCACAGCAATGGTAA
GGACTTGAAGTGTGAATGGGAGCTTCTGGAAAGGAAGGCCGTGGCCTGGATGCGTGCCCATGCAGGCTCCACCATGCCTTCGGTTGTGAA
AGCTGCTATTACTTTCCTGAAGTCATCTGTGGATCCTGCTATCTTTGCCTTTTGAAGATACCATCCAGAAAAAGAAGTGCCTTTAATTTG
CTACTGTCATTTCCTCTAGTATCACTTTTGCTGTGATGATGTGTTCTTGTGTATTATAACTCTTTATTTTTTGCCATAAAAGTAAAGGAT
GCTTACTCCACTTCGCTTCTCTGCTCCAGGTTCACTTTGGATATGATCTTTCTTTTCCCAACATATGCCCTCAGAAAAGTGACAGTGGTC
CCAGAACCTATTCCCTTTCTTGAGGGAGTTCAAAACATTCATAGGCAGTAATGTTCCTCCCAGGGTTTCCAGGGAAACAACATGAAAAAC
AGGTGACATGAACTACAGACTAAAGATTGCAGCATTTATGTTAGAGAATGCTTGAATTAGAGAATTTTCTGCATTATCTTTGTCTGTTCA
CTTTCTATCTTATATACTTATCAGGGCCATACTGGTAAGCTTGCGTAGGAGGAGTTAGAGGGAAGTTGAAAGCCAACATCTGGATCAATG
TAATGTCAAGATCACAAAGACAGAGACTGCAGGGGTCCACTGTGAGAGGTGACACTGTTGGGGACCTTCCTGATTCATTCTTCTTGGGCT
TTGCTAGCCTGTACAACCTACATGTCTTTTCTTCCACTGCCTGAAAGACTTGGGTTGAACTATAACTGTTGGAGAGAGATGTTCCTCTTT
AATCATGAAACACCTTAAGAAGTCTATAATGCAATCCTTAGTCCTACCCTGAACCTATGTGTCCTCTAAGTCAGGCCCTGATCTAGTGCA
GTAAAGGGAAGGGTGGGCTTAATGGGAGCTTTGCCTGGGACCTGAACCTGGAGCACTTACCGCATTAGGAAGAAAGGAGCTCCCCGTAAT
CGTTCCTGACCCTTGTGTCTCATATACCCTATCCTGGTGGAAATGACCCTATTTGATATGCTGTCCCTTAAAATAACTTGTATCAATATT
AAAATGACTATTTCTACCCTTTGATGAGTAAATGCAGTGGTTCTTAAAGTGGTCTCGTCTCCCTACCCCACAATATTTTGGTACTGCCAC
TTTGGGAAGCCAAACTAGGATAGTAAATTGACCGGAACACAGTTGTGGAAATTTGACCTGAAGTTAGTGAAATAAAACTTAGTAGGGAAA
AAAAGCTTAGCAAGAGGTCTACTCCTCCATAGATTCATTTATTGAACTTACATTGGTTTTATTGTCCCTTGTTTTCTGTTCCAGCTTTTC
TGATGCCTCCACTGTTCCCATGGTATCCTGACCCTCTATCTTCTGTTGTAGGCTGACTTCTTTTATATGAAGCAAGTAAAGGATACTAAT
AAGAATACCACTGTAGAATCCTGACCATACCCTTAAATAGTTATGTGATGATGGGCAAATGATTTCACCCTCAGGCACTTAATATCCTCA
TCTGTAAAACTAAGGGATTAAACTAGAACTTTATTAACACTTTCGAGTTCCACTCAGAATTCCTAGAGGAACATCGGTGACTTTTCACTC
AGAAAGTGGGTGGACTAGGCCTGAGTTTCTTTAAGTTGTTGAGTTACCTGGTATTAGGAAGACTTGTGTGACTTGCATAGTGGACTCTAA
TCTCTCAGTCTTTCTTCCAAGTTTGTTTATGCTGAATGTGATCTGCGGAACAGGGTTGTTAGAAATGCAGCTTTTTAGAAATGCAGAATT
TTAATCGATACCAGGAACTACTTTATTTAACAAGGCTCCCAGGTATCATGCATGCACATTGAAGTTTGAAAAGTAAAGGCTTAATATTTT

>In-frame_ENST00000307138_ENST00000456829_TCGA-IN-8462_RALGAPA1_chr14_36231915_-_VWA5A_chr11_124007280_length(amino acids)=416AA_start in transcript=424_stop in transcript=1674
MGAGCGSGSGSGSDRMFSKKPHGDVKKSTQKVLDTKKDALTRLKHLRIVIENAESIDLKQFFDQHFSHIYYVFFENFVTIEASLKQKGHK
SQREELDAILFIFEKILQLLPERIHQRWQFHSIGLILKKLLHTGNSLKAAETTGEVCLKYTLQGKTFEDKVTFPLQPKPDVNLTIHRLAA
KSLLQTKDMGLRETPASDKKDALNLSLESGVISSFTAFIAINKELNKPVQGPLAHRDVPRPILLGASAPLKIKCQSGFRKALHSDRPPSA
SQPRGELMCYKAKTFQMDDYSLCGLISHKDQHSPGFGENHLVQLIYHQNANGSWDLNEDLAKILGMSLEEIMAAQPAELVDSSGWATILA

--------------------------------------------------------------

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Fusion Gene PPI Analysis for RALGAPA1-VWA5A


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for RALGAPA1-VWA5A


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for RALGAPA1-VWA5A


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneRALGAPA1C0026827Muscle hypotonia1GENOMICS_ENGLAND
HgeneRALGAPA1C3714756Intellectual Disability1GENOMICS_ENGLAND